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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= bmte10h19
         (676 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

U97669-1|AAB91371.1| 2321|Homo sapiens Notch3 protein.                 33   1.2  
AF058900-1|AAC14346.1| 2321|Homo sapiens Notch3 protein.               33   1.2  
AC004663-1|AAC15789.1| 2281|Homo sapiens Notch 3 protein.              33   1.2  
AB209447-1|BAD92684.1| 1289|Homo sapiens Notch homolog 3 variant...    33   1.2  
BC063856-1|AAH63856.1|  319|Homo sapiens sprouty homolog 1, anta...    32   2.1  
AY590694-1|AAT06102.1|  316|Homo sapiens sprouty 1 protein.            32   2.1  
AY192146-1|AAP20102.1|  319|Homo sapiens sprouty 1 protein protein.    32   2.1  
M75161-1|AAA58617.1|  593|Homo sapiens granulin protein.               30   6.5  
M73980-1|AAA60614.1| 2444|Homo sapiens TAN1 protein.                   30   8.6  
AL592301-5|CAI13934.1| 2555|Homo sapiens Notch homolog 1, transl...    30   8.6  
AL354671-1|CAI16149.1| 2555|Homo sapiens Notch homolog 1, transl...    30   8.6  
AF308602-1|AAG33848.1| 2556|Homo sapiens NOTCH 1 protein.              30   8.6  

>U97669-1|AAB91371.1| 2321|Homo sapiens Notch3 protein.
          Length = 2321

 Score = 32.7 bits (71), Expect = 1.2
 Identities = 31/101 (30%), Positives = 38/101 (37%), Gaps = 20/101 (19%)
 Frame = +3

Query: 339 TCQECPS---CACPSDF------NPSTP-SMYDCRKYGHCLPSNDLITRFECLPNF---- 476
           TC   P    C CP+ +      NP+ P +   CR  G C  S DL     CLP F    
Sbjct: 173 TCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQN 232

Query: 477 -PTGI-----FRCTTGETLGSGADKGCCYQCPEYFAYQHMT 581
               +      RC  G T   G +   C QCP  +  Q  T
Sbjct: 233 CEVNVDDCPGHRCLNGGTCVDGVNTYNC-QCPPEWTGQFCT 272


>AF058900-1|AAC14346.1| 2321|Homo sapiens Notch3 protein.
          Length = 2321

 Score = 32.7 bits (71), Expect = 1.2
 Identities = 31/101 (30%), Positives = 38/101 (37%), Gaps = 20/101 (19%)
 Frame = +3

Query: 339 TCQECPS---CACPSDF------NPSTP-SMYDCRKYGHCLPSNDLITRFECLPNF---- 476
           TC   P    C CP+ +      NP+ P +   CR  G C  S DL     CLP F    
Sbjct: 173 TCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQN 232

Query: 477 -PTGI-----FRCTTGETLGSGADKGCCYQCPEYFAYQHMT 581
               +      RC  G T   G +   C QCP  +  Q  T
Sbjct: 233 CEVNVDDCPGHRCLNGGTCVDGVNTYNC-QCPPEWTGQFCT 272


>AC004663-1|AAC15789.1| 2281|Homo sapiens Notch 3 protein.
          Length = 2281

 Score = 32.7 bits (71), Expect = 1.2
 Identities = 31/101 (30%), Positives = 38/101 (37%), Gaps = 20/101 (19%)
 Frame = +3

Query: 339 TCQECPS---CACPSDF------NPSTP-SMYDCRKYGHCLPSNDLITRFECLPNF---- 476
           TC   P    C CP+ +      NP+ P +   CR  G C  S DL     CLP F    
Sbjct: 133 TCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQN 192

Query: 477 -PTGI-----FRCTTGETLGSGADKGCCYQCPEYFAYQHMT 581
               +      RC  G T   G +   C QCP  +  Q  T
Sbjct: 193 CEVNVDDCPGHRCLNGGTCVDGVNTYNC-QCPPEWTGQFCT 232


>AB209447-1|BAD92684.1| 1289|Homo sapiens Notch homolog 3 variant
           protein.
          Length = 1289

 Score = 32.7 bits (71), Expect = 1.2
 Identities = 31/101 (30%), Positives = 38/101 (37%), Gaps = 20/101 (19%)
 Frame = +3

Query: 339 TCQECPS---CACPSDF------NPSTP-SMYDCRKYGHCLPSNDLITRFECLPNF---- 476
           TC   P    C CP+ +      NP+ P +   CR  G C  S DL     CLP F    
Sbjct: 176 TCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQN 235

Query: 477 -PTGI-----FRCTTGETLGSGADKGCCYQCPEYFAYQHMT 581
               +      RC  G T   G +   C QCP  +  Q  T
Sbjct: 236 CEVNVDDCPGHRCLNGGTCVDGVNTYNC-QCPPEWTGQFCT 275


>BC063856-1|AAH63856.1|  319|Homo sapiens sprouty homolog 1,
           antagonist of FGF signaling (Drosophila) protein.
          Length = 319

 Score = 31.9 bits (69), Expect = 2.1
 Identities = 25/92 (27%), Positives = 37/92 (40%), Gaps = 6/92 (6%)
 Frame = +3

Query: 330 NKETCQECPSCACPSDFNPST-PSMYDCRKYGHCLPSNDLITRFECLPNFPTGIF-RCTT 503
           +K  C++C  C C     P T PS   C +   CL S + +  +        GIF  C+ 
Sbjct: 177 HKFICEQCGKCKCGECTAPRTLPSCLACNR--QCLCSAESMVEYGTCMCLVKGIFYHCSN 234

Query: 504 GETLGSGADKGC-CYQ---CPEYFAYQHMTFY 587
            +   S +D  C C Q   C  Y     M+ +
Sbjct: 235 DDEGDSYSDNPCSCSQSHCCSRYLCMGAMSLF 266


>AY590694-1|AAT06102.1|  316|Homo sapiens sprouty 1 protein.
          Length = 316

 Score = 31.9 bits (69), Expect = 2.1
 Identities = 25/92 (27%), Positives = 37/92 (40%), Gaps = 6/92 (6%)
 Frame = +3

Query: 330 NKETCQECPSCACPSDFNPST-PSMYDCRKYGHCLPSNDLITRFECLPNFPTGIF-RCTT 503
           +K  C++C  C C     P T PS   C +   CL S + +  +        GIF  C+ 
Sbjct: 174 HKFICEQCGKCKCGECTAPRTLPSCLACNR--QCLCSAESMVEYGTCMCLVKGIFYHCSN 231

Query: 504 GETLGSGADKGC-CYQ---CPEYFAYQHMTFY 587
            +   S +D  C C Q   C  Y     M+ +
Sbjct: 232 DDEGDSYSDNPCSCSQSHCCSRYLCMGAMSLF 263


>AY192146-1|AAP20102.1|  319|Homo sapiens sprouty 1 protein protein.
          Length = 319

 Score = 31.9 bits (69), Expect = 2.1
 Identities = 25/92 (27%), Positives = 37/92 (40%), Gaps = 6/92 (6%)
 Frame = +3

Query: 330 NKETCQECPSCACPSDFNPST-PSMYDCRKYGHCLPSNDLITRFECLPNFPTGIF-RCTT 503
           +K  C++C  C C     P T PS   C +   CL S + +  +        GIF  C+ 
Sbjct: 177 HKFICEQCGKCKCGECTAPRTLPSCLACNR--QCLCSAESMVEYGTCMCLVKGIFYHCSN 234

Query: 504 GETLGSGADKGC-CYQ---CPEYFAYQHMTFY 587
            +   S +D  C C Q   C  Y     M+ +
Sbjct: 235 DDEGDSYSDNPCSCSQSHCCSRYLCMGAMSLF 266


>M75161-1|AAA58617.1|  593|Homo sapiens granulin protein.
          Length = 593

 Score = 30.3 bits (65), Expect = 6.5
 Identities = 12/43 (27%), Positives = 17/43 (39%)
 Frame = +3

Query: 342 CQECPSCACPSDFNPSTPSMYDCRKYGHCLPSNDLITRFECLP 470
           C   P   C SD     P  Y C   G C   ++++   E +P
Sbjct: 388 CCPIPEAVCCSDHQHCCPQRYTCVAEGQCQRGSEIVAGLEKMP 430


>M73980-1|AAA60614.1| 2444|Homo sapiens TAN1 protein.
          Length = 2444

 Score = 29.9 bits (64), Expect = 8.6
 Identities = 15/41 (36%), Positives = 21/41 (51%)
 Frame = +3

Query: 354 PSCACPSDFNPSTPSMYDCRKYGHCLPSNDLITRFECLPNF 476
           P+C  P  + P +PS   C+  G C P+ D+     CLP F
Sbjct: 213 PNCERP--YVPCSPS--PCQNGGTCRPTGDVTHECACLPGF 249


>AL592301-5|CAI13934.1| 2555|Homo sapiens Notch homolog 1,
           translocation-associated (Drosophila) protein.
          Length = 2555

 Score = 29.9 bits (64), Expect = 8.6
 Identities = 15/41 (36%), Positives = 21/41 (51%)
 Frame = +3

Query: 354 PSCACPSDFNPSTPSMYDCRKYGHCLPSNDLITRFECLPNF 476
           P+C  P  + P +PS   C+  G C P+ D+     CLP F
Sbjct: 213 PNCERP--YVPCSPS--PCQNGGTCRPTGDVTHECACLPGF 249


>AL354671-1|CAI16149.1| 2555|Homo sapiens Notch homolog 1,
           translocation-associated (Drosophila) protein.
          Length = 2555

 Score = 29.9 bits (64), Expect = 8.6
 Identities = 15/41 (36%), Positives = 21/41 (51%)
 Frame = +3

Query: 354 PSCACPSDFNPSTPSMYDCRKYGHCLPSNDLITRFECLPNF 476
           P+C  P  + P +PS   C+  G C P+ D+     CLP F
Sbjct: 213 PNCERP--YVPCSPS--PCQNGGTCRPTGDVTHECACLPGF 249


>AF308602-1|AAG33848.1| 2556|Homo sapiens NOTCH 1 protein.
          Length = 2556

 Score = 29.9 bits (64), Expect = 8.6
 Identities = 15/41 (36%), Positives = 21/41 (51%)
 Frame = +3

Query: 354 PSCACPSDFNPSTPSMYDCRKYGHCLPSNDLITRFECLPNF 476
           P+C  P  + P +PS   C+  G C P+ D+     CLP F
Sbjct: 213 PNCERP--YVPCSPS--PCQNGGTCRPTGDVTHECACLPGF 249


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 87,507,438
Number of Sequences: 237096
Number of extensions: 1808508
Number of successful extensions: 3119
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 2998
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3114
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 7615267504
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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