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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= bmte10h14
         (673 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_Q4RFE2 Cluster: Chromosome 8 SCAF15119, whole genome sh...   149   5e-35
UniRef50_Q28BZ2 Cluster: Histidine triad nucleotide binding prot...   146   4e-34
UniRef50_UPI0000D55AC3 Cluster: PREDICTED: similar to histidine ...   135   8e-31
UniRef50_A7SFV5 Cluster: Predicted protein; n=1; Nematostella ve...   135   8e-31
UniRef50_UPI00015B4104 Cluster: PREDICTED: hypothetical protein;...   132   7e-30
UniRef50_Q16YN6 Cluster: Protein kinase C inhibitor, putative; n...   128   1e-28
UniRef50_Q9NQE9 Cluster: Histidine triad nucleotide binding prot...   128   1e-28
UniRef50_UPI0000DB7407 Cluster: PREDICTED: similar to histidine ...   121   1e-26
UniRef50_Q4RR26 Cluster: Chromosome 14 SCAF15003, whole genome s...   118   2e-25
UniRef50_Q6IIA4 Cluster: HDC19222; n=1; Drosophila melanogaster|...   112   6e-24
UniRef50_UPI0000E47ACB Cluster: PREDICTED: hypothetical protein,...   108   1e-22
UniRef50_Q9VQ59 Cluster: CG15362-PA; n=3; Sophophora|Rep: CG1536...   100   4e-20
UniRef50_Q0V966 Cluster: Zgc:136256; n=4; Danio rerio|Rep: Zgc:1...    99   5e-20
UniRef50_Q01IH1 Cluster: OSIGBa0159I10.14 protein; n=6; Magnolio...    97   3e-19
UniRef50_Q84VV6 Cluster: At4g16566; n=2; Arabidopsis thaliana|Re...    94   2e-18
UniRef50_UPI00006CEB92 Cluster: HIT domain containing protein; n...    88   2e-16
UniRef50_Q4PA08 Cluster: Putative uncharacterized protein; n=1; ...    84   3e-15
UniRef50_Q18227 Cluster: Putative uncharacterized protein; n=2; ...    80   6e-14
UniRef50_Q83DE2 Cluster: HIT family protein; n=24; Bacteria|Rep:...    73   5e-12
UniRef50_Q54DF5 Cluster: Putative uncharacterized protein; n=1; ...    71   3e-11
UniRef50_UPI00006CC86C Cluster: HIT domain containing protein; n...    69   8e-11
UniRef50_O66536 Cluster: Uncharacterized HIT-like protein aq_141...    66   7e-10
UniRef50_A6VZM3 Cluster: Histidine triad (HIT) protein; n=4; Pro...    65   1e-09
UniRef50_A6T373 Cluster: HIT family protein; n=20; Betaproteobac...    65   1e-09
UniRef50_UPI0000D55BA8 Cluster: PREDICTED: similar to aprataxin;...    64   3e-09
UniRef50_Q8KGB0 Cluster: HIT family protein; n=10; Bacteria|Rep:...    63   5e-09
UniRef50_A5K5T5 Cluster: Protein kinase C inhibitor, putative; n...    63   5e-09
UniRef50_Q1CY35 Cluster: HIT domain protein; n=3; Bacteria|Rep: ...    63   7e-09
UniRef50_Q5R0G3 Cluster: HIT family hydrolase; n=20; Proteobacte...    62   9e-09
UniRef50_Q55V28 Cluster: Putative uncharacterized protein; n=1; ...    62   9e-09
UniRef50_Q7W2X6 Cluster: MttA/Hcf106 family protein; n=30; Burkh...    62   2e-08
UniRef50_Q5WBH5 Cluster: Histidine triad protein involved in cel...    62   2e-08
UniRef50_Q892R5 Cluster: Hit family protein; n=16; Bacteria|Rep:...    61   2e-08
UniRef50_Q182D4 Cluster: Histidine triad nucleotide-binding prot...    61   2e-08
UniRef50_Q3J6P8 Cluster: Histidine triad (HIT) protein; n=5; Pro...    61   3e-08
UniRef50_Q9BX68 Cluster: Histidine triad nucleotide-binding prot...    60   6e-08
UniRef50_Q2F5W9 Cluster: Protein kinase C inhibitor; n=3; Endopt...    59   8e-08
UniRef50_Q8F673 Cluster: HIT family hydrolase; n=6; cellular org...    59   1e-07
UniRef50_Q1YR93 Cluster: Protein kinase C inhibitor; n=2; Gammap...    59   1e-07
UniRef50_A7HMY4 Cluster: Histidine triad (HIT) protein; n=2; The...    59   1e-07
UniRef50_Q5TVU2 Cluster: ENSANGP00000027488; n=1; Anopheles gamb...    59   1e-07
UniRef50_A7A616 Cluster: Putative uncharacterized protein; n=2; ...    58   1e-07
UniRef50_O07817 Cluster: Protein hitA; n=7; Betaproteobacteria|R...    58   1e-07
UniRef50_Q7K6B1 Cluster: Protein kinase c inhibitor-like protein...    58   2e-07
UniRef50_UPI00015B4880 Cluster: PREDICTED: similar to FHA-HIT; n...    58   3e-07
UniRef50_A3DF72 Cluster: Histidine triad (HIT) protein; n=2; Clo...    58   3e-07
UniRef50_Q5Z134 Cluster: Putative uncharacterized protein; n=1; ...    57   3e-07
UniRef50_Q74MW7 Cluster: NEQ519; n=1; Nanoarchaeum equitans|Rep:...    57   3e-07
UniRef50_P61799 Cluster: Aprataxin; n=21; Deuterostomia|Rep: Apr...    57   3e-07
UniRef50_P61802 Cluster: Aprataxin; n=1; Ciona intestinalis|Rep:...    57   4e-07
UniRef50_Q4JN62 Cluster: Predicted protein kinase C inhibitor ch...    56   6e-07
UniRef50_UPI000038E073 Cluster: hypothetical protein Faci_030002...    56   1e-06
UniRef50_A7H6R9 Cluster: Histidine triad (HIT) protein; n=14; Ba...    56   1e-06
UniRef50_Q7PTZ0 Cluster: ENSANGP00000012901; n=2; Anopheles gamb...    56   1e-06
UniRef50_Q8PVK5 Cluster: Hit-like protein; n=4; Methanosarcinace...    56   1e-06
UniRef50_Q58276 Cluster: Uncharacterized HIT-like protein MJ0866...    55   1e-06
UniRef50_UPI0000D555E3 Cluster: PREDICTED: similar to Hypothetic...    55   2e-06
UniRef50_Q5K261 Cluster: Putative uncharacterized protein pkci; ...    55   2e-06
UniRef50_Q6MTB0 Cluster: Histidine triad protein; n=2; Mycoplasm...    54   2e-06
UniRef50_Q9HIK0 Cluster: Cell-cycle regulation histidine triad (...    54   4e-06
UniRef50_A3HAI2 Cluster: Histidine triad (HIT) protein; n=2; The...    54   4e-06
UniRef50_P0ACE9 Cluster: HIT-like protein ycfF; n=109; Bacteria|...    53   5e-06
UniRef50_P32084 Cluster: Uncharacterized HIT-like protein Synpcc...    53   5e-06
UniRef50_A7FTJ1 Cluster: HIT family protein; n=4; Clostridium bo...    53   7e-06
UniRef50_P49773 Cluster: Histidine triad nucleotide-binding prot...    53   7e-06
UniRef50_UPI000155CE00 Cluster: PREDICTED: similar to aprataxin;...    52   1e-05
UniRef50_Q4LEG8 Cluster: Histidine triad protein; n=1; unculture...    52   1e-05
UniRef50_Q2LVF0 Cluster: Hit family hydrolase; n=1; Syntrophus a...    52   1e-05
UniRef50_Q558W0 Cluster: Putative uncharacterized protein; n=3; ...    52   1e-05
UniRef50_A0BUI5 Cluster: Chromosome undetermined scaffold_129, w...    52   1e-05
UniRef50_P94252 Cluster: Uncharacterized HIT-like protein BB_037...    52   1e-05
UniRef50_Q1MR92 Cluster: 141aa long hypothetical histidine triad...    52   2e-05
UniRef50_Q7Z2E3 Cluster: Aprataxin; n=44; Euteleostomi|Rep: Apra...    52   2e-05
UniRef50_Q67LQ3 Cluster: HIT family protein; n=1; Symbiobacteriu...    51   2e-05
UniRef50_A1SHY4 Cluster: Histidine triad (HIT) protein precursor...    51   2e-05
UniRef50_Q970Y2 Cluster: 141aa long hypothetical histidine triad...    51   2e-05
UniRef50_A4FZK6 Cluster: Histidine triad (HIT) protein; n=5; Met...    51   2e-05
UniRef50_UPI000050FA96 Cluster: COG0537: Diadenosine tetraphosph...    51   3e-05
UniRef50_A5GQU3 Cluster: HIT family hydrolase; n=10; Bacteria|Re...    50   4e-05
UniRef50_A0W3X6 Cluster: Histidine triad (HIT) protein; n=3; Bac...    50   4e-05
UniRef50_A7AQA5 Cluster: HIT domain containing protein; n=1; Bab...    50   4e-05
UniRef50_Q11066 Cluster: Uncharacterized HIT-like protein Rv1262...    50   4e-05
UniRef50_Q023M8 Cluster: Histidine triad (HIT) protein; n=2; Bac...    50   5e-05
UniRef50_A4F9S9 Cluster: Protein kinase C inhibitor; n=3; Actino...    50   5e-05
UniRef50_A1G4L9 Cluster: Histidine triad (HIT) protein; n=3; Bac...    50   5e-05
UniRef50_Q5TX49 Cluster: ENSANGP00000029056; n=1; Anopheles gamb...    50   5e-05
UniRef50_Q65J74 Cluster: Putative uncharacterized protein; n=1; ...    50   7e-05
UniRef50_Q4K6N7 Cluster: HIT family protein; n=1; Pseudomonas fl...    50   7e-05
UniRef50_A0LM74 Cluster: Histidine triad (HIT) protein; n=1; Syn...    50   7e-05
UniRef50_Q83MZ3 Cluster: HIT-like protein; n=2; Tropheryma whipp...    49   9e-05
UniRef50_Q6L1V3 Cluster: Asymmetrical bis(5'-nucleosyl)-tetrapho...    49   9e-05
UniRef50_O07513 Cluster: Protein hit; n=16; Bacillaceae|Rep: Pro...    49   9e-05
UniRef50_Q7R1Q2 Cluster: GLP_28_16821_16420; n=1; Giardia lambli...    49   1e-04
UniRef50_Q7NAX8 Cluster: Hit-like; n=1; Mycoplasma gallisepticum...    48   2e-04
UniRef50_Q4P3W7 Cluster: Putative uncharacterized protein; n=1; ...    48   2e-04
UniRef50_P73481 Cluster: Uncharacterized HIT-like protein slr123...    48   2e-04
UniRef50_Q9K9A6 Cluster: Cell-cycle regulation histidine triad; ...    48   2e-04
UniRef50_Q88X03 Cluster: Cell-cycle regulation histidine triad p...    48   2e-04
UniRef50_A3EUM2 Cluster: Histidine triad protein; n=1; Leptospir...    48   2e-04
UniRef50_UPI000050FB45 Cluster: COG0537: Diadenosine tetraphosph...    48   3e-04
UniRef50_Q3W573 Cluster: Histidine triad (HIT) protein; n=3; Act...    48   3e-04
UniRef50_Q02WI9 Cluster: Diadenosine tetraphosphate (Ap4A) hydro...    48   3e-04
UniRef50_A0LCF6 Cluster: Histidine triad (HIT) protein; n=3; Bac...    48   3e-04
UniRef50_UPI00015C430C Cluster: HIT family protein; n=1; Strepto...    47   4e-04
UniRef50_Q98RK0 Cluster: HIT-LIKE PROTEIN; n=2; Mycoplasma|Rep: ...    47   4e-04
UniRef50_Q727L0 Cluster: HIT family protein; n=2; Deltaproteobac...    47   4e-04
UniRef50_Q2BQP2 Cluster: HIT domain protein; n=1; Neptuniibacter...    47   4e-04
UniRef50_Q1FG87 Cluster: Histidine triad (HIT) protein; n=5; Clo...    47   4e-04
UniRef50_A6PM84 Cluster: Histidine triad (HIT) protein; n=1; Vic...    47   4e-04
UniRef50_A5Z767 Cluster: Putative uncharacterized protein; n=1; ...    47   4e-04
UniRef50_Q4N9V7 Cluster: Protein kinase C interacting protein 1,...    47   4e-04
UniRef50_Q16F08 Cluster: Putative uncharacterized protein; n=2; ...    47   4e-04
UniRef50_Q8K9I9 Cluster: Uncharacterized HIT-like protein BUsg_3...    47   4e-04
UniRef50_Q8EW55 Cluster: Histidine triad protein HIT; n=1; Mycop...    47   5e-04
UniRef50_Q8DK69 Cluster: Histidine triad nucleotide-binding prot...    47   5e-04
UniRef50_A7D556 Cluster: Histidine triad (HIT) protein; n=1; Hal...    47   5e-04
UniRef50_UPI00003C03A1 Cluster: PREDICTED: similar to aprataxin;...    46   6e-04
UniRef50_Q6A7Y9 Cluster: Putative cell-cycle regulation histidin...    46   6e-04
UniRef50_Q4FMD8 Cluster: Diadenosine tetraphosphate (Ap4A) hydro...    46   6e-04
UniRef50_Q93IL6 Cluster: Histidine nucleotide-binding protein; n...    46   6e-04
UniRef50_Q2BE03 Cluster: Cell-cycle regulation histidine triad, ...    46   6e-04
UniRef50_Q5KLA4 Cluster: Hydrolase, putative; n=2; Dikarya|Rep: ...    46   6e-04
UniRef50_A7BYS1 Cluster: HIT family protein; n=2; Proteobacteria...    46   8e-04
UniRef50_Q9V017 Cluster: Histidine triad (HIT) protein; n=4; The...    46   8e-04
UniRef50_Q5UZ82 Cluster: Histidine triad protein; n=4; Halobacte...    46   8e-04
UniRef50_Q74I95 Cluster: Hit protein; n=5; Lactobacillus|Rep: Hi...    46   0.001
UniRef50_A4J7H7 Cluster: Histidine triad (HIT) protein; n=4; cel...    46   0.001
UniRef50_Q74ND2 Cluster: NEQ213; n=1; Nanoarchaeum equitans|Rep:...    46   0.001
UniRef50_Q7W2C9 Cluster: Histidine triad protein; n=4; Proteobac...    45   0.001
UniRef50_Q6AEC2 Cluster: Putative uncharacterized protein; n=3; ...    45   0.001
UniRef50_Q702F5 Cluster: Putative HIT superfamily hydrolase; n=1...    45   0.001
UniRef50_P42856 Cluster: 14 kDa zinc-binding protein; n=11; Euka...    45   0.001
UniRef50_A0RUN5 Cluster: Diadenosine tetraphosphate hydrolase; n...    45   0.002
UniRef50_Q9ZDL1 Cluster: Uncharacterized HIT-like protein RP317;...    45   0.002
UniRef50_Q6I3E1 Cluster: HIT family protein; n=9; Bacillus cereu...    44   0.003
UniRef50_A7H3E9 Cluster: HIT family protein; n=11; Campylobacter...    44   0.003
UniRef50_A6WDH4 Cluster: Histidine triad (HIT) protein; n=2; Act...    44   0.003
UniRef50_A1AWF6 Cluster: Histidine triad (HIT) protein; n=1; Can...    44   0.003
UniRef50_A1RXN8 Cluster: Histidine triad (HIT) protein; n=1; The...    44   0.003
UniRef50_P49774 Cluster: Uncharacterized HIT-like protein ML2237...    44   0.003
UniRef50_Q9PQL9 Cluster: Probable HIT protein; n=1; Ureaplasma p...    44   0.003
UniRef50_Q9SA09 Cluster: F28K20.9 protein; n=7; Magnoliophyta|Re...    44   0.003
UniRef50_A5BDT4 Cluster: Putative uncharacterized protein; n=2; ...    44   0.003
UniRef50_Q0VNN6 Cluster: HIT family protein; n=1; Alcanivorax bo...    44   0.004
UniRef50_A6FN65 Cluster: HIT family protein; n=1; Roseobacter sp...    44   0.004
UniRef50_A1VWA8 Cluster: Histidine triad (HIT) protein; n=5; cel...    44   0.004
UniRef50_A0B7E7 Cluster: Histidine triad (HIT) protein; n=1; Met...    44   0.004
UniRef50_Q97S70 Cluster: HIT family protein; n=37; Streptococcac...    43   0.006
UniRef50_Q6F1M1 Cluster: Putative nucleotidyl hydrolase/transfer...    43   0.006
UniRef50_Q0LZX4 Cluster: Histidine triad (HIT) protein precursor...    43   0.006
UniRef50_A5KTI5 Cluster: Histidine triad (HIT) protein; n=1; can...    43   0.006
UniRef50_A6DMK8 Cluster: Hit-like protein; n=1; Lentisphaera ara...    43   0.008
UniRef50_A5KT99 Cluster: Histidine triad (HIT) protein; n=2; can...    43   0.008
UniRef50_A4XT81 Cluster: Histidine triad (HIT) protein; n=7; Pse...    43   0.008
UniRef50_Q9PK09 Cluster: Uncharacterized HIT-like protein TC_066...    43   0.008
UniRef50_Q28QE4 Cluster: Histidine triad (HIT) protein; n=1; Jan...    42   0.010
UniRef50_A1SG63 Cluster: Histidine triad (HIT) protein; n=3; Act...    42   0.010
UniRef50_A0YDE8 Cluster: Probable HIT family protein; n=1; marin...    42   0.010
UniRef50_Q4DJ40 Cluster: Adenosine 5'-monophosphoramidase, putat...    42   0.010
UniRef50_Q9KDM3 Cluster: Hit-like protein involved in cell-cycle...    42   0.014
UniRef50_Q8SRE4 Cluster: HIT FAMILY PROTEIN; n=1; Encephalitozoo...    42   0.014
UniRef50_A1RYX9 Cluster: Histidine triad (HIT) protein; n=1; The...    42   0.014
UniRef50_P95937 Cluster: Uncharacterized HIT-like protein SSO216...    42   0.018
UniRef50_P75504 Cluster: Uncharacterized 16.1 kDa HIT-like prote...    42   0.018
UniRef50_Q8FTW3 Cluster: Putative uncharacterized protein; n=1; ...    41   0.024
UniRef50_Q9JN38 Cluster: Putative HIT-like protein; n=2; Mycopla...    41   0.024
UniRef50_A1VGI9 Cluster: Histidine triad (HIT) protein; n=2; Des...    41   0.024
UniRef50_Q9Y8Y9 Cluster: HIT family protein; n=1; Aeropyrum pern...    41   0.024
UniRef50_Q8YU88 Cluster: All2466 protein; n=5; Cyanobacteria|Rep...    41   0.031
UniRef50_Q4FXZ6 Cluster: Putative uncharacterized protein; n=5; ...    41   0.031
UniRef50_Q5Z2D6 Cluster: Putative uncharacterized protein; n=1; ...    40   0.041
UniRef50_Q2LT70 Cluster: Hypothetical cytosolic protein; n=1; Sy...    40   0.041
UniRef50_Q6SI40 Cluster: HIT family protein; n=1; uncultured bac...    40   0.041
UniRef50_A4YEP9 Cluster: Histidine triad (HIT) protein; n=1; Met...    40   0.041
UniRef50_Q88TZ2 Cluster: Cell-cycle regulation histidine triad p...    40   0.055
UniRef50_Q2YZP9 Cluster: Putative uncharacterized protein; n=2; ...    40   0.055
UniRef50_A4VSJ7 Cluster: Diadenosine tetraphosphate (Ap4A) hydro...    40   0.055
UniRef50_Q8ZTP1 Cluster: HIT family protein; n=4; Pyrobaculum|Re...    40   0.055
UniRef50_P32083 Cluster: Uncharacterized 13.1 kDa HIT-like prote...    40   0.055
UniRef50_Q8MSG8 Cluster: Aprataxin-like protein; n=6; Sophophora...    40   0.055
UniRef50_Q9RTX9 Cluster: Hit family protein; n=2; Deinococcus|Re...    40   0.072
UniRef50_Q5CSR7 Cluster: Histidine triad (HIT) family zinc bindi...    40   0.072
UniRef50_Q6YPU5 Cluster: Diadenosine tetraphosphate hydrolase; n...    39   0.096
UniRef50_Q6NFF8 Cluster: HIT family protein; n=4; Corynebacteriu...    39   0.096
UniRef50_A6G534 Cluster: HIT-family protein; n=1; Plesiocystis p...    39   0.096
UniRef50_Q57WA7 Cluster: Putative uncharacterized protein; n=1; ...    39   0.096
UniRef50_Q04344 Cluster: Hit family protein 1; n=22; Dikarya|Rep...    39   0.096
UniRef50_A7R099 Cluster: Chromosome undetermined scaffold_300, w...    39   0.13 
UniRef50_A7TKH2 Cluster: Putative uncharacterized protein; n=1; ...    39   0.13 
UniRef50_P64382 Cluster: Uncharacterized HIT-like protein HP_040...    39   0.13 
UniRef50_Q1V185 Cluster: Histidine triad (HIT) protein; n=3; Bac...    38   0.17 
UniRef50_Q1QBU6 Cluster: Histidine triad (HIT) protein; n=2; Psy...    38   0.17 
UniRef50_A7BDL4 Cluster: Putative uncharacterized protein; n=1; ...    38   0.17 
UniRef50_A6DCA2 Cluster: Histidine triad (HIT) protein; n=1; Cam...    38   0.17 
UniRef50_A5I340 Cluster: Hit family protein; n=4; Clostridium bo...    38   0.17 
UniRef50_A5CF29 Cluster: Protein kinase C inhibitor 1; n=1; Orie...    38   0.17 
UniRef50_A6S7H6 Cluster: Predicted protein; n=2; Sclerotiniaceae...    38   0.17 
UniRef50_Q7MKL5 Cluster: Diadenosine tetraphosphate hydrolase; n...    38   0.22 
UniRef50_Q31N56 Cluster: Putative uncharacterized protein; n=2; ...    38   0.22 
UniRef50_A2E0S0 Cluster: HIT domain containing protein; n=1; Tri...    38   0.22 
UniRef50_UPI0000DBEF88 Cluster: UPI0000DBEF88 related cluster; n...    38   0.29 
UniRef50_A6Q3Z1 Cluster: Histidine triad family protein; n=16; E...    38   0.29 
UniRef50_A5UPG3 Cluster: Histidine triad (HIT) protein; n=5; Chl...    38   0.29 
UniRef50_A0RX45 Cluster: Asymmetrical bis(5'-nucleosyl)-tetrapho...    38   0.29 
UniRef50_Q3A4F7 Cluster: HIT (HINT, histidine triad) family prot...    37   0.39 
UniRef50_Q10MW4 Cluster: Basic helix-loop-helix, putative, expre...    37   0.39 
UniRef50_A1RZ81 Cluster: Galactose-1-phosphate uridylyltransfera...    37   0.39 
UniRef50_Q03D63 Cluster: Diadenosine tetraphosphate (Ap4A) hydro...    37   0.51 
UniRef50_Q5B6X2 Cluster: Putative uncharacterized protein; n=2; ...    37   0.51 
UniRef50_Q979C0 Cluster: Histidine triad protein [HIT]; n=3; The...    37   0.51 
UniRef50_Q8YHI2 Cluster: BIS(5'-NUCLEOSYL)-TETRAPHOSPHATASE; n=2...    36   0.67 
UniRef50_Q7M8Z0 Cluster: HIT-FAMILY PROTEIN; n=12; Epsilonproteo...    36   0.67 
UniRef50_Q3K5R5 Cluster: Histidine triad (HIT) protein; n=9; Bac...    36   0.67 
UniRef50_A3HA11 Cluster: Histidine triad (HIT) protein; n=1; Cal...    36   0.89 
UniRef50_A3H762 Cluster: Galactose-1-phosphate uridylyltransfera...    36   0.89 
UniRef50_P49776 Cluster: Bis(5'-nucleosyl)-tetraphosphatase [asy...    36   0.89 
UniRef50_A1WAF8 Cluster: Histidine triad (HIT) protein; n=5; Bet...    36   1.2  
UniRef50_Q3E2P9 Cluster: Galactose-1-phosphate uridylyltransfera...    35   1.6  
UniRef50_A4AKY1 Cluster: Putative uncharacterized protein; n=1; ...    35   1.6  
UniRef50_A7QKZ8 Cluster: Chromosome chr8 scaffold_115, whole gen...    35   2.1  
UniRef50_Q8F4J7 Cluster: HIT family hydrolase; n=4; Leptospira|R...    34   2.7  
UniRef50_Q5GT45 Cluster: HIT family hydrolase; n=4; Rickettsiale...    34   2.7  
UniRef50_Q03WU6 Cluster: Diadenosine tetraphosphate (Ap4A) hydro...    34   2.7  
UniRef50_O76463 Cluster: Nitrilase and fragile histidine triad f...    34   2.7  
UniRef50_Q1IUV2 Cluster: Galactose-1-phosphate uridylyltransfera...    34   3.6  
UniRef50_Q9V2L0 Cluster: Hit histidine triad protein; n=6; Archa...    34   3.6  
UniRef50_A3DN62 Cluster: Histidine triad (HIT) protein; n=1; Sta...    34   3.6  
UniRef50_Q83GK4 Cluster: Putative uncharacterized protein; n=3; ...    33   4.8  
UniRef50_Q74CH2 Cluster: HIT family protein; n=3; Desulfuromonad...    33   4.8  
UniRef50_A4BW57 Cluster: HIT family protein; n=14; Bacteroidetes...    33   4.8  
UniRef50_A2TZ69 Cluster: Putative cell-cycle regulation histidin...    33   4.8  
UniRef50_Q23921 Cluster: Protein pkiA; n=4; Dictyostelium discoi...    33   4.8  
UniRef50_Q6AQ03 Cluster: Putative uncharacterized protein; n=1; ...    33   6.3  
UniRef50_A5UUJ2 Cluster: Putative uncharacterized protein precur...    33   6.3  
UniRef50_A0LI77 Cluster: Type III restriction enzyme, res subuni...    33   6.3  
UniRef50_A7I5E0 Cluster: Histidine triad (HIT) protein; n=1; Can...    33   6.3  
UniRef50_Q6MP02 Cluster: Hit family hydrolase; n=1; Bdellovibrio...    33   8.3  
UniRef50_Q560L7 Cluster: Putative uncharacterized protein; n=2; ...    33   8.3  

>UniRef50_Q4RFE2 Cluster: Chromosome 8 SCAF15119, whole genome
           shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 8
           SCAF15119, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 166

 Score =  149 bits (362), Expect = 5e-35
 Identities = 62/131 (47%), Positives = 93/131 (70%), Gaps = 1/131 (0%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           CIFC I NK   TE+L+ D E+  FRDI+P +  H L +P +H+ + KSL+     L+ R
Sbjct: 29  CIFCKIVNKELETELLHCDGEISCFRDIRPGAPHHYLVVPTKHVGNCKSLSKEHVPLVQR 88

Query: 421 MMSISRELLSKNNLS-IEDARFGYHWPPFRSVKHLHLHTIAPESEMGFIGRVIFKKNSYW 597
           M+ + +E+L KN+++ + DARFG+HWPPF SV HLHLH +AP S+MGF+ R+I++ NSYW
Sbjct: 89  MVELGKEILQKNDVTDLSDARFGFHWPPFCSVTHLHLHVLAPASQMGFMSRLIYRLNSYW 148

Query: 598 FVSPEYVASIL 630
           F++ + +  +L
Sbjct: 149 FITADQLIQLL 159


>UniRef50_Q28BZ2 Cluster: Histidine triad nucleotide binding protein
           3; n=2; Tetrapoda|Rep: Histidine triad nucleotide
           binding protein 3 - Xenopus tropicalis (Western clawed
           frog) (Silurana tropicalis)
          Length = 153

 Score =  146 bits (354), Expect = 4e-34
 Identities = 60/126 (47%), Positives = 90/126 (71%), Gaps = 2/126 (1%)
 Frame = +1

Query: 241 CIFCNIANKLE-GTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLN 417
           CIFC IANK E G E+L+ DD++  F+DI+PA   H L +PK+H+   K+LT    +L+ 
Sbjct: 19  CIFCRIANKQESGAELLHSDDDLVCFKDIRPAVTHHYLVVPKKHVGTCKTLTKDHVQLIK 78

Query: 418 RMMSISRELLSKNNLS-IEDARFGYHWPPFRSVKHLHLHTIAPESEMGFIGRVIFKKNSY 594
            MM + +  L KNN++ +ED R G+H+PPF S+ HLHLH +AP S++GF+ R+I++ NSY
Sbjct: 79  TMMEVGKSTLQKNNVTDLEDIRLGFHYPPFCSISHLHLHVLAPASQLGFLSRMIYRVNSY 138

Query: 595 WFVSPE 612
           WF++ +
Sbjct: 139 WFITAD 144


>UniRef50_UPI0000D55AC3 Cluster: PREDICTED: similar to histidine
           triad protein 4; n=1; Tribolium castaneum|Rep:
           PREDICTED: similar to histidine triad protein 4 -
           Tribolium castaneum
          Length = 138

 Score =  135 bits (327), Expect = 8e-31
 Identities = 57/126 (45%), Positives = 85/126 (67%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           CIFC I +     EI ++DD++ +F+DIKPAS+ H L +PK HI +V SL+     L+N 
Sbjct: 4   CIFCKIISGDAPAEIFHQDDKMIIFKDIKPASKHHFLAVPKEHIPNVNSLSKNQIPLIND 63

Query: 421 MMSISRELLSKNNLSIEDARFGYHWPPFRSVKHLHLHTIAPESEMGFIGRVIFKKNSYWF 600
           +++ S+++L+    +++D R G+H PPF SV HLHLH I+P SEM FI   +FK NS+WF
Sbjct: 64  LIAKSKQVLADKGGNLDDTRLGFHLPPFNSVSHLHLHIISPVSEMSFISSFVFKPNSWWF 123

Query: 601 VSPEYV 618
            S + +
Sbjct: 124 TSVDQI 129


>UniRef50_A7SFV5 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 163

 Score =  135 bits (327), Expect = 8e-31
 Identities = 53/126 (42%), Positives = 86/126 (68%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           C+FC I++K + T I+YED+E   F+D++PA+  H L IPK+H  + KSLT  D  L+ +
Sbjct: 11  CVFCKISSKEQETRIIYEDEETLTFKDLRPATDHHYLVIPKQHYGNPKSLTGDDLPLVEK 70

Query: 421 MMSISRELLSKNNLSIEDARFGYHWPPFRSVKHLHLHTIAPESEMGFIGRVIFKKNSYWF 600
           +M + +++L + N + ED   G+HWPPF S++HLHLH I+  S+M F  R I++  S+WF
Sbjct: 71  LMDVGKKVLVQQNANTEDTVIGFHWPPFNSIQHLHLHVISDASQMRFASRHIYRPGSWWF 130

Query: 601 VSPEYV 618
            + +++
Sbjct: 131 ATVDWM 136


>UniRef50_UPI00015B4104 Cluster: PREDICTED: hypothetical protein;
           n=1; Nasonia vitripennis|Rep: PREDICTED: hypothetical
           protein - Nasonia vitripennis
          Length = 144

 Score =  132 bits (319), Expect = 7e-30
 Identities = 60/128 (46%), Positives = 79/128 (61%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           C+FC I  K E    +YEDD V   +DI PAS  H L IPK HI + K L    +EL ++
Sbjct: 11  CVFCKILKKEEPGVNIYEDDHVACIKDINPASDHHYLIIPKNHIVNAKVLNKEHEELYDK 70

Query: 421 MMSISRELLSKNNLSIEDARFGYHWPPFRSVKHLHLHTIAPESEMGFIGRVIFKKNSYWF 600
           M++    ++ K  L     R G+HWPPF +V HLHLH I+P  +MGFI  ++FK NS+WF
Sbjct: 71  MVATVDTIVDKLGLVKNSTRTGFHWPPFTTVGHLHLHVISPVEKMGFIKNMMFKPNSHWF 130

Query: 601 VSPEYVAS 624
           VS +YV S
Sbjct: 131 VSTDYVKS 138


>UniRef50_Q16YN6 Cluster: Protein kinase C inhibitor, putative; n=2;
           Culicidae|Rep: Protein kinase C inhibitor, putative -
           Aedes aegypti (Yellowfever mosquito)
          Length = 154

 Score =  128 bits (309), Expect = 1e-28
 Identities = 53/128 (41%), Positives = 84/128 (65%), Gaps = 2/128 (1%)
 Frame = +1

Query: 241 CIFCNIANKLE-GTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLN 417
           CIFC I    +    I+YE++ +C+F+DI+PA+  H+L +PK H++DV+SLT A++ LL+
Sbjct: 12  CIFCKIVTGQDPNASIVYENERICIFKDIRPAAEHHLLAVPKYHLDDVRSLTEAERPLLD 71

Query: 418 RM-MSISRELLSKNNLSIEDARFGYHWPPFRSVKHLHLHTIAPESEMGFIGRVIFKKNSY 594
            M   +   L  +  + + +  FG+H PPF +VKHLH+H + P   MGFI R+IF+ NS 
Sbjct: 72  EMRQELGNVLKDQFQVDLAEVLFGFHVPPFTTVKHLHMHGMGPVGSMGFISRMIFRPNSM 131

Query: 595 WFVSPEYV 618
           WF + + +
Sbjct: 132 WFKTDQTI 139


>UniRef50_Q9NQE9 Cluster: Histidine triad nucleotide binding protein
           3; n=22; Euteleostomi|Rep: Histidine triad nucleotide
           binding protein 3 - Homo sapiens (Human)
          Length = 182

 Score =  128 bits (309), Expect = 1e-28
 Identities = 50/129 (38%), Positives = 91/129 (70%), Gaps = 3/129 (2%)
 Frame = +1

Query: 241 CIFCNIANKLE-GTEILY-EDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELL 414
           C+FC IA + + GTE+L+ E++++  F+DIKPA+  H L +PK+HI + ++L     EL+
Sbjct: 48  CVFCRIAGRQDPGTELLHCENEDLICFKDIKPAATHHYLVVPKKHIGNCRTLRKDQVELV 107

Query: 415 NRMMSISRELLSKNNLS-IEDARFGYHWPPFRSVKHLHLHTIAPESEMGFIGRVIFKKNS 591
             M+++ + +L +NN +   + R G+H PPF S+ HLHLH +AP  ++GF+ +++++ NS
Sbjct: 108 ENMVTVGKTILERNNFTDFTNVRMGFHMPPFCSISHLHLHVLAPVDQLGFLSKLVYRVNS 167

Query: 592 YWFVSPEYV 618
           YWF++ +++
Sbjct: 168 YWFITADHL 176


>UniRef50_UPI0000DB7407 Cluster: PREDICTED: similar to histidine
           triad protein 4; n=2; Apis mellifera|Rep: PREDICTED:
           similar to histidine triad protein 4 - Apis mellifera
          Length = 140

 Score =  121 bits (292), Expect = 1e-26
 Identities = 56/130 (43%), Positives = 76/130 (58%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           CIFC+I N  E +E +YED+ V   +DI P S  H L +PK HI + K L     EL ++
Sbjct: 7   CIFCDIINNKEPSEKIYEDNYVTCIKDIHPVSTHHYLILPKEHIRNAKQLKPEHSELYDK 66

Query: 421 MMSISRELLSKNNLSIEDARFGYHWPPFRSVKHLHLHTIAPESEMGFIGRVIFKKNSYWF 600
           M++    +  K  L     R G+HWPPF +V HLHLH I+P S + F  R +++  S WF
Sbjct: 67  MLAAIDIISQKQGLDRAVTRTGFHWPPFNTVSHLHLHVISPISNIKFYKRYMYEPGSCWF 126

Query: 601 VSPEYVASIL 630
           VS +YV S L
Sbjct: 127 VSTDYVKSRL 136


>UniRef50_Q4RR26 Cluster: Chromosome 14 SCAF15003, whole genome
           shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 14
           SCAF15003, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 277

 Score =  118 bits (283), Expect = 2e-25
 Identities = 50/123 (40%), Positives = 79/123 (64%), Gaps = 1/123 (0%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           C FC IA+K   TEIL+ D+E+  FRD+KP +  H L + +RHI++ + L +    L+ R
Sbjct: 155 CPFCQIADKQTNTEILFSDEELLCFRDVKPGAETHFLVVTRRHIDNCRMLQTQHIPLVER 214

Query: 421 MMSISRELLSKNNL-SIEDARFGYHWPPFRSVKHLHLHTIAPESEMGFIGRVIFKKNSYW 597
           M+ ++R +L +N + + ED R G+H PPF SV HLHLH + P S+M    ++ +   S+W
Sbjct: 215 MVEVARSVLEENKVHNSEDNRMGFHLPPFTSVPHLHLHVLCPASKMNVRAQLRYGPQSHW 274

Query: 598 FVS 606
           F++
Sbjct: 275 FIT 277



 Score = 75.8 bits (178), Expect = 9e-13
 Identities = 35/89 (39%), Positives = 52/89 (58%), Gaps = 1/89 (1%)
 Frame = +1

Query: 292 EDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLS-I 468
           +D ++  F+DI PA+  H L +P  HI    SL     +L+ RM  + R +L    ++ +
Sbjct: 1   QDKDLVCFKDIYPAAPHHYLVVPVPHIISCHSLQRRHVKLVERMAEMGRAVLRDQGITDL 60

Query: 469 EDARFGYHWPPFRSVKHLHLHTIAPESEM 555
            D R G+H PPF SV HLHLH +AP S++
Sbjct: 61  SDIRLGFHQPPFTSVHHLHLHVLAPASQI 89


>UniRef50_Q6IIA4 Cluster: HDC19222; n=1; Drosophila
           melanogaster|Rep: HDC19222 - Drosophila melanogaster
           (Fruit fly)
          Length = 139

 Score =  112 bits (270), Expect = 6e-24
 Identities = 49/121 (40%), Positives = 80/121 (66%), Gaps = 1/121 (0%)
 Frame = +1

Query: 241 CIFCNIAN-KLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLN 417
           CIFC I++ ++  T +  E+D+  +F+DIKPAS+ H L + K+H   +K L  +   L+ 
Sbjct: 6   CIFCLISDGRIPSTVLEVENDDFVIFQDIKPASQHHYLAVTKKHYASLKDLNKSHDSLVQ 65

Query: 418 RMMSISRELLSKNNLSIEDARFGYHWPPFRSVKHLHLHTIAPESEMGFIGRVIFKKNSYW 597
            M +  ++LL    +S++DA FG+H PPF +VKHLH+H I+P ++M F+ ++IF+  S W
Sbjct: 66  LMENALKDLLVSKGVSVDDALFGFHLPPFITVKHLHMHAISPRTQMTFLSKMIFRP-SVW 124

Query: 598 F 600
           F
Sbjct: 125 F 125


>UniRef50_UPI0000E47ACB Cluster: PREDICTED: hypothetical protein,
           partial; n=1; Strongylocentrotus purpuratus|Rep:
           PREDICTED: hypothetical protein, partial -
           Strongylocentrotus purpuratus
          Length = 104

 Score =  108 bits (260), Expect = 1e-22
 Identities = 43/104 (41%), Positives = 67/104 (64%)
 Frame = +1

Query: 295 DDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLSIED 474
           ++  CVF DI+P+++ H+L IPK H  +VKSL      L+  +  +   +L     +I D
Sbjct: 1   NEAACVFHDIRPSTKEHLLIIPKSHHGNVKSLDKCQIPLVQYLYQVGEAVLEARGGNIAD 60

Query: 475 ARFGYHWPPFRSVKHLHLHTIAPESEMGFIGRVIFKKNSYWFVS 606
           AR G+HWPPF ++ HLHLH + P SEM  +G+++ + NS+WFV+
Sbjct: 61  ARVGFHWPPFNTIDHLHLHVVYPTSEMNLLGKIMNRPNSFWFVT 104


>UniRef50_Q9VQ59 Cluster: CG15362-PA; n=3; Sophophora|Rep:
           CG15362-PA - Drosophila melanogaster (Fruit fly)
          Length = 168

 Score =  100 bits (239), Expect = 4e-20
 Identities = 48/122 (39%), Positives = 71/122 (58%), Gaps = 2/122 (1%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYE--DDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELL 414
           C FC+ A++ +G   + E   DE  +F+D  PA+R H L IPK H + +K+L  +   L+
Sbjct: 33  CFFCDFAHRRQGPPPILEVETDEYVIFKDKYPAARLHYLAIPKEHFDSLKALNKSHVGLV 92

Query: 415 NRMMSISRELLSKNNLSIEDARFGYHWPPFRSVKHLHLHTIAPESEMGFIGRVIFKKNSY 594
            RM     E L   N+  ++A  G+H PPF SV+HLHLH I P ++M F  ++ F   S+
Sbjct: 93  RRMEQGMMEFLRSQNVDPKEAIVGFHLPPFISVRHLHLHGIFPPADMSFGNKISFMP-SF 151

Query: 595 WF 600
           WF
Sbjct: 152 WF 153


>UniRef50_Q0V966 Cluster: Zgc:136256; n=4; Danio rerio|Rep:
           Zgc:136256 - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 160

 Score =   99 bits (238), Expect = 5e-20
 Identities = 53/133 (39%), Positives = 77/133 (57%), Gaps = 2/133 (1%)
 Frame = +1

Query: 241 CIFCNIANKLEG-TEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLN 417
           CIFC IA   +  TEIL ED++   FRDI P +  H L IPK+HI    SL + D  L+ 
Sbjct: 23  CIFCTIAKGDDRYTEILAEDEDFVCFRDINPGAPHHYLVIPKKHIYSCLSLYADDISLVR 82

Query: 418 RMMSISRELLSKNNLS-IEDARFGYHWPPFRSVKHLHLHTIAPESEMGFIGRVIFKKNSY 594
            M  + R +L  NN++ ++D   G+H PP+ +V HLHL+ +AP S++      I K  + 
Sbjct: 83  AMAEMGRNVLKANNVTDLKDISLGFHVPPYITVPHLHLYVLAPYSQL--YKWAINKFRTN 140

Query: 595 WFVSPEYVASILM 633
           W+++ E    ILM
Sbjct: 141 WYINEEKTVEILM 153


>UniRef50_Q01IH1 Cluster: OSIGBa0159I10.14 protein; n=6;
           Magnoliophyta|Rep: OSIGBa0159I10.14 protein - Oryza
           sativa (Rice)
          Length = 141

 Score = 97.5 bits (232), Expect = 3e-19
 Identities = 46/104 (44%), Positives = 68/104 (65%), Gaps = 4/104 (3%)
 Frame = +1

Query: 241 CIFCNIANKLEG--TEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSL--TSADKE 408
           C+FC IA +     T +LY DD V  F+DI P++  H L IP  HI  V +L  T+ D +
Sbjct: 5   CVFCPIARRDPACNTVLLYSDDRVMAFKDINPSAFRHYLVIPIEHIPTVNNLQRTTEDHQ 64

Query: 409 LLNRMMSISRELLSKNNLSIEDARFGYHWPPFRSVKHLHLHTIA 540
           L++ M+++ R+LL+++  + E+ RFG+H PPF SV HLHLH +A
Sbjct: 65  LVSHMLAVGRDLLNRDAPNSEEQRFGFHQPPFNSVDHLHLHCLA 108


>UniRef50_Q84VV6 Cluster: At4g16566; n=2; Arabidopsis thaliana|Rep:
           At4g16566 - Arabidopsis thaliana (Mouse-ear cress)
          Length = 146

 Score = 94.3 bits (224), Expect = 2e-18
 Identities = 48/103 (46%), Positives = 64/103 (62%), Gaps = 3/103 (2%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKE--LL 414
           CIFC I      T +L+ D++V  F+DIKPA++ H L IPK HI  V  L   D++  L+
Sbjct: 8   CIFCEIVRNPTTTRLLHTDEKVIAFQDIKPAAQRHYLVIPKEHIPTVNDLQRRDEDYSLV 67

Query: 415 NRMMSISRELLSKN-NLSIEDARFGYHWPPFRSVKHLHLHTIA 540
             M+S+ ++LL K+   SI   RFG+H PPF SV HLHLH  A
Sbjct: 68  RHMLSVGQQLLQKDAPQSIH--RFGFHQPPFNSVDHLHLHCFA 108


>UniRef50_UPI00006CEB92 Cluster: HIT domain containing protein; n=1;
           Tetrahymena thermophila SB210|Rep: HIT domain containing
           protein - Tetrahymena thermophila SB210
          Length = 142

 Score = 87.8 bits (208), Expect = 2e-16
 Identities = 45/114 (39%), Positives = 63/114 (55%), Gaps = 1/114 (0%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPAS-RFHILTIPKRHIEDVKSLTSADKELLN 417
           CIFC I +        YEDDE+  F DI  AS + HIL  PKRHI++V  L   D EL+ 
Sbjct: 9   CIFCQIRDSKGNQAPFYEDDEIFAFEDINIASSKRHILICPKRHIKNVNELNYLDIELVK 68

Query: 418 RMMSISRELLSKNNLSIEDARFGYHWPPFRSVKHLHLHTIAPESEMGFIGRVIF 579
           R+  +  + L +++ + +  RFGYH PP  S+ HLHLH         F  ++I+
Sbjct: 69  RLEQVGIQTLQESHPN-QQYRFGYHSPPLNSIDHLHLHGFVLPISNCFNNKIIY 121


>UniRef50_Q4PA08 Cluster: Putative uncharacterized protein; n=1;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 196

 Score = 83.8 bits (198), Expect = 3e-15
 Identities = 41/102 (40%), Positives = 63/102 (61%), Gaps = 3/102 (2%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           C+FCN+    +   I+ ED+++  F D  P +  H+L IP+ HI +V+SLT    EL+ +
Sbjct: 47  CVFCNVTP--DRFRIVIEDEKLICFTDRSPGAAIHLLVIPRNHIANVQSLTHNHTELVRQ 104

Query: 421 MMSISR---ELLSKNNLSIEDARFGYHWPPFRSVKHLHLHTI 537
           M ++     +L+S +N + E  RFG+H PP RSV HLHLH +
Sbjct: 105 MQALGNKALDLVSTSNCAPE-RRFGFHIPPIRSVDHLHLHCL 145


>UniRef50_Q18227 Cluster: Putative uncharacterized protein; n=2;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 175

 Score = 79.8 bits (188), Expect = 6e-14
 Identities = 47/117 (40%), Positives = 62/117 (52%), Gaps = 7/117 (5%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           C FC+I    +  + L E+    V  DIKP ++ H L + K+HI     LT AD  LL  
Sbjct: 11  CKFCDIVKNKKELQ-LKENKSCVVINDIKPKAKNHYLVLSKQHIAKPTDLTVADVPLLEE 69

Query: 421 MMSISRELLSKNNL------SIEDA-RFGYHWPPFRSVKHLHLHTIAPESEMGFIGR 570
           M    RELL ++        ++ED  R G+H PP  SV HLH+H I P S+MG I R
Sbjct: 70  MEKTGRELLREHLKKKGEADTVEDMLRIGFHLPPLLSVHHLHMHIIYPISDMGLISR 126


>UniRef50_Q83DE2 Cluster: HIT family protein; n=24; Bacteria|Rep:
           HIT family protein - Coxiella burnetii
          Length = 113

 Score = 73.3 bits (172), Expect = 5e-12
 Identities = 37/101 (36%), Positives = 57/101 (56%), Gaps = 2/101 (1%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           C+FC IA K E  E++YED +V  F D  P +  HIL IP RHIE +  +T  D++LL  
Sbjct: 4   CVFCKIA-KGEIGELIYEDKQVVAFNDAAPQAPIHILVIPHRHIETINDVTPGDEDLLGH 62

Query: 421 MMSISRELLSKNNLSIEDAR--FGYHWPPFRSVKHLHLHTI 537
           M+ ++  L    N++ +  R     +    ++V H+HLH +
Sbjct: 63  MVVVATRLAHDKNMAADGYRLVMNCNRNGGQAVFHIHLHLL 103


>UniRef50_Q54DF5 Cluster: Putative uncharacterized protein; n=1;
           Dictyostelium discoideum AX4|Rep: Putative
           uncharacterized protein - Dictyostelium discoideum AX4
          Length = 166

 Score = 70.9 bits (166), Expect = 3e-11
 Identities = 42/118 (35%), Positives = 63/118 (53%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           C FC+  N     +I++++  V VF D  P +  H L  P+ HI  +K+LT  D  +L  
Sbjct: 37  CPFCDYPND----KIIFQN--VIVFNDRTPKATVHYLICPREHIVSIKTLTQKDIPVLVE 90

Query: 421 MMSISRELLSKNNLSIEDARFGYHWPPFRSVKHLHLHTIAPESEMGFIGRVIFKKNSY 594
           M  ++ +L+++          G+H PPF SVKHLHLH + P     F  +  FKK+SY
Sbjct: 91  MKQVADQLIAEKFPGQSGIVLGFHSPPFYSVKHLHLHLLVPP----FTPK--FKKHSY 142


>UniRef50_UPI00006CC86C Cluster: HIT domain containing protein; n=1;
           Tetrahymena thermophila SB210|Rep: HIT domain containing
           protein - Tetrahymena thermophila SB210
          Length = 181

 Score = 69.3 bits (162), Expect = 8e-11
 Identities = 37/100 (37%), Positives = 59/100 (59%), Gaps = 1/100 (1%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPAS-RFHILTIPKRHIEDVKSLTSADKELLN 417
           C FC+I    +   I++++D V    DI  AS + HIL  P +HIE+   LTS D +LL+
Sbjct: 7   CEFCDILQNKKNL-IIFQNDIVFAIEDIDLASSQRHILVCPIKHIENSSYLTSNDLQLLD 65

Query: 418 RMMSISRELLSKNNLSIEDARFGYHWPPFRSVKHLHLHTI 537
            +  +  ++L K++   ++ ++GYH PP  S+ HLH H I
Sbjct: 66  EIHKVCEQILQKSHPG-KEYKYGYHIPPHVSIDHLHYHGI 104


>UniRef50_O66536 Cluster: Uncharacterized HIT-like protein aq_141;
           n=9; Bacteria|Rep: Uncharacterized HIT-like protein
           aq_141 - Aquifex aeolicus
          Length = 121

 Score = 66.1 bits (154), Expect = 7e-10
 Identities = 38/106 (35%), Positives = 56/106 (52%), Gaps = 7/106 (6%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           CIFC I       + +YEDD+V  F DI P +  HIL IPK+HI  +++L   D+ L+  
Sbjct: 6   CIFCKIVRGEVPAKKVYEDDKVLAFHDINPVAPVHILIIPKKHIMGIQTLEPEDECLVGH 65

Query: 421 MMSISRELLSKNNLS-IEDARFGYHW------PPFRSVKHLHLHTI 537
           M  ++R++     ++  E+   GY           +SV HLHLH I
Sbjct: 66  MFYVARKIAEDLGIAPDENLNKGYRLVFNVGKDAGQSVFHLHLHLI 111


>UniRef50_A6VZM3 Cluster: Histidine triad (HIT) protein; n=4;
           Proteobacteria|Rep: Histidine triad (HIT) protein -
           Marinomonas sp. MWYL1
          Length = 113

 Score = 65.3 bits (152), Expect = 1e-09
 Identities = 31/101 (30%), Positives = 52/101 (51%), Gaps = 2/101 (1%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           C+FC I        IL+EDD+V  F DI P +  H L IPKRHI  +  LT  D  ++ +
Sbjct: 3   CLFCKIVKGDIPANILFEDDDVIAFEDIMPKAPTHFLVIPKRHISTLNDLTDEDAPVVGK 62

Query: 421 MMSISRELLSKNNLSIEDARFGYHWPPF--RSVKHLHLHTI 537
           + + + ++  +  +S    R   +      ++V H+H+H +
Sbjct: 63  LQTTAAKIAKQKGISNAGYRVVMNCNEMGGQTVYHIHMHVL 103


>UniRef50_A6T373 Cluster: HIT family protein; n=20;
           Betaproteobacteria|Rep: HIT family protein -
           Janthinobacterium sp. (strain Marseille) (Minibacterium
           massiliensis)
          Length = 128

 Score = 65.3 bits (152), Expect = 1e-09
 Identities = 28/74 (37%), Positives = 44/74 (59%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           CIFC IA K    +I+YEDD++  F DI PA+  H L IPK+H+  +   T+ D  LL +
Sbjct: 8   CIFCKIAAKQIPAQIIYEDDDLLAFNDINPAAPVHFLIIPKKHVATLADCTTEDAALLGK 67

Query: 421 MMSISRELLSKNNL 462
           +  ++ +L  +  +
Sbjct: 68  ISLLAPKLAQEQGV 81


>UniRef50_UPI0000D55BA8 Cluster: PREDICTED: similar to aprataxin;
           n=1; Tribolium castaneum|Rep: PREDICTED: similar to
           aprataxin - Tribolium castaneum
          Length = 199

 Score = 64.1 bits (149), Expect = 3e-09
 Identities = 31/84 (36%), Positives = 47/84 (55%)
 Frame = +1

Query: 295 DDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLSIED 474
           DD + + RD  P ++FH L +PK  I  +KS+TS    LL  M  ++ EL+S++      
Sbjct: 41  DDLIHIIRDKYPKAKFHYLVLPKEDITSIKSVTSTHLSLLKHMEQVALELISRDKHKEST 100

Query: 475 ARFGYHWPPFRSVKHLHLHTIAPE 546
            + GYH  P  S+  LHLH I+ +
Sbjct: 101 FKIGYHAEP--SMSRLHLHVISDD 122


>UniRef50_Q8KGB0 Cluster: HIT family protein; n=10; Bacteria|Rep:
           HIT family protein - Chlorobium tepidum
          Length = 128

 Score = 63.3 bits (147), Expect = 5e-09
 Identities = 37/117 (31%), Positives = 56/117 (47%), Gaps = 5/117 (4%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           CIFC IA       ++Y++D V  F DI P +  H+L IP  HI  +  L   D E+  +
Sbjct: 8   CIFCKIATGHIPANLVYKNDHVAAFHDINPVAPIHVLIIPLEHIRSLSDLKDGDSEIAAQ 67

Query: 421 MMSISRELLSKNNLSIEDAR--FGYHWPPFRSVKHLHLHTIAPESEMG---FIGRVI 576
           ++  +R +  K  +     R  F       +SV H+H H I  ++ MG   F GR +
Sbjct: 68  ILLAARIVAEKTGVLESGYRLVFNNGEDALQSVGHIHAHLIGGKT-MGWPPFAGREV 123


>UniRef50_A5K5T5 Cluster: Protein kinase C inhibitor, putative; n=5;
           cellular organisms|Rep: Protein kinase C inhibitor,
           putative - Plasmodium vivax
          Length = 185

 Score = 63.3 bits (147), Expect = 5e-09
 Identities = 42/104 (40%), Positives = 58/104 (55%), Gaps = 5/104 (4%)
 Frame = +1

Query: 244 IFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSAD---KELL 414
           IF  IA K    +++YEDD+V  F DI P +  HIL IPK   + +  L+ A+   KE+L
Sbjct: 76  IFGKIARKEVKVDLVYEDDKVLAFNDINPQAPVHILVIPKMR-DGLTRLSKAEERHKEIL 134

Query: 415 NRMMSISRELLSKNNLSIEDARFGYHWPP--FRSVKHLHLHTIA 540
             MM    E++ KNNL   D R   +  P   +SV +LHLH +A
Sbjct: 135 GHMMWAVSEIVKKNNLG--DFRLVVNNGPEACQSVYYLHLHILA 176


>UniRef50_Q1CY35 Cluster: HIT domain protein; n=3; Bacteria|Rep: HIT
           domain protein - Myxococcus xanthus (strain DK 1622)
          Length = 116

 Score = 62.9 bits (146), Expect = 7e-09
 Identities = 33/106 (31%), Positives = 55/106 (51%), Gaps = 6/106 (5%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           C+FC I + L   +++Y DD    F DI P +  H+L IP +HI  V  +T+ D+EL+  
Sbjct: 4   CLFCKIRDGLIPAKVVYRDDVCVAFEDINPQAPTHVLFIPHKHIPTVNDITTEDRELVGH 63

Query: 421 MMSISRELLSKNNLSIEDARFGY------HWPPFRSVKHLHLHTIA 540
           +   + ++  +   +  D   GY      H    ++V H+HLH +A
Sbjct: 64  LFIAAAKVAQERGHA--DPSDGYRVVMNTHAHAGQTVFHIHLHLLA 107


>UniRef50_Q5R0G3 Cluster: HIT family hydrolase; n=20;
           Proteobacteria|Rep: HIT family hydrolase - Idiomarina
           loihiensis
          Length = 122

 Score = 62.5 bits (145), Expect = 9e-09
 Identities = 33/108 (30%), Positives = 60/108 (55%), Gaps = 2/108 (1%)
 Frame = +1

Query: 244 IFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRM 423
           IF  I N+    +I+YEDD+   F+DI P + FH L IPK+ I     +   +  L+  +
Sbjct: 6   IFTKIINRDIPADIIYEDDKALAFKDINPQAPFHCLIIPKQPIATANDINEDNAGLVGHL 65

Query: 424 MSISRELLSKNNLSIEDARFGYHWPPF--RSVKHLHLHTIAPESEMGF 561
             ++ +L +++N S +  R   +   +  ++V H+HLH +A + +MG+
Sbjct: 66  YVVAAKLAAEHNFSQDGYRLVMNCNEYGGQTVYHIHLHMLAGK-QMGW 112


>UniRef50_Q55V28 Cluster: Putative uncharacterized protein; n=1;
           Filobasidiella neoformans|Rep: Putative uncharacterized
           protein - Cryptococcus neoformans (Filobasidiella
           neoformans)
          Length = 127

 Score = 62.5 bits (145), Expect = 9e-09
 Identities = 40/121 (33%), Positives = 60/121 (49%), Gaps = 8/121 (6%)
 Frame = +1

Query: 292 EDDEVCVFRDIKPASRFHILTIPKRHI-EDVKSLTSADKELLNRMMSISRELLSKNNLSI 468
           +D E+  F D  P +  H+L IP+ H+   V+ LT     LL+ M ++SR L+     S 
Sbjct: 2   QDQELIAFHDRTPRAVTHLLIIPRSHVASSVRQLTHEHLPLLDSMAALSRTLVP----SK 57

Query: 469 EDARFGYHWPPFRSVKHLHLHTIAPESEMGFIGRVIFKKNSY-------WFVSPEYVASI 627
              + G+H PPF SV H+HLH  +      FIG+  +   +Y       WFV+ E   + 
Sbjct: 58  PTPKLGFHIPPFSSVPHIHLHVFS--GPHTFIGKFKYPVTTYAAGKGLGWFVTIEQARNT 115

Query: 628 L 630
           L
Sbjct: 116 L 116


>UniRef50_Q7W2X6 Cluster: MttA/Hcf106 family protein; n=30;
           Burkholderiales|Rep: MttA/Hcf106 family protein -
           Bordetella parapertussis
          Length = 122

 Score = 61.7 bits (143), Expect = 2e-08
 Identities = 27/72 (37%), Positives = 41/72 (56%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           CIFC IA      + ++EDDE   F DI PA+  H+L IP+RH+  ++ +   D + L R
Sbjct: 5   CIFCKIARGEIPAKKVFEDDEFVAFHDINPAAPVHLLLIPRRHVVSLQDIAEGDADWLGR 64

Query: 421 MMSISRELLSKN 456
           M  ++  L + N
Sbjct: 65  MTVLASRLAAGN 76


>UniRef50_Q5WBH5 Cluster: Histidine triad protein involved in
           cell-cycle regulation; n=1; Bacillus clausii
           KSM-K16|Rep: Histidine triad protein involved in
           cell-cycle regulation - Bacillus clausii (strain
           KSM-K16)
          Length = 134

 Score = 61.7 bits (143), Expect = 2e-08
 Identities = 34/99 (34%), Positives = 57/99 (57%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           C+FC IANK   + I+YED++   F DI+P +  H+L IPKRH E + +L   ++E ++ 
Sbjct: 3   CLFCAIANKEVKSHIVYEDEQAIAFLDIQPINPGHMLVIPKRHQEALHTL--GEQEYIDV 60

Query: 421 MMSISRELLSKNNLSIEDARFGYHWPPFRSVKHLHLHTI 537
           M ++ R L  + + ++   + G     F    HLH+H +
Sbjct: 61  MKAV-RRLSKQVDDTLRPKKVGVAIAGFDQA-HLHVHIV 97


>UniRef50_Q892R5 Cluster: Hit family protein; n=16; Bacteria|Rep:
           Hit family protein - Clostridium tetani
          Length = 114

 Score = 61.3 bits (142), Expect = 2e-08
 Identities = 29/101 (28%), Positives = 59/101 (58%), Gaps = 2/101 (1%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           CIFC I      +E +YED+ +  F+DI P++  H+L IPK+HI+++  L+  D ++++ 
Sbjct: 4   CIFCKIVKGDIPSEKVYEDELILAFKDISPSAPTHVLVIPKKHIKNLNELSDNDAKIISH 63

Query: 421 MMSISRELLSKNNLSIEDARFGYHW--PPFRSVKHLHLHTI 537
           +    +EL  + +++ +  R   +      ++V+H+H H +
Sbjct: 64  IYIKIKELAQQLDINEKGYRVVTNCGEQGGQTVEHIHFHLL 104


>UniRef50_Q182D4 Cluster: Histidine triad nucleotide-binding
           protein; n=7; Bacteria|Rep: Histidine triad
           nucleotide-binding protein - Clostridium difficile
           (strain 630)
          Length = 116

 Score = 61.3 bits (142), Expect = 2e-08
 Identities = 30/103 (29%), Positives = 54/103 (52%), Gaps = 3/103 (2%)
 Frame = +1

Query: 241 CIFCNIAN-KLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLN 417
           CIFC IAN ++  T++ YEDD V  F D+ P + +HIL +PK+H + +  +   + ++++
Sbjct: 3   CIFCKIANGEIPSTKV-YEDDRVLAFNDLNPVAPYHILVVPKKHYDSLIDIPDKEMDIVS 61

Query: 418 RMMSISRELLSKNNLSIEDARF--GYHWPPFRSVKHLHLHTIA 540
            +  +  ++  +        R          + VKHLH H +A
Sbjct: 62  HIHVVINKIAKEKGFDQTGFRVINNCGSDGGQEVKHLHYHILA 104


>UniRef50_Q3J6P8 Cluster: Histidine triad (HIT) protein; n=5;
           Proteobacteria|Rep: Histidine triad (HIT) protein -
           Nitrosococcus oceani (strain ATCC 19707 / NCIMB 11848)
          Length = 115

 Score = 60.9 bits (141), Expect = 3e-08
 Identities = 33/113 (29%), Positives = 55/113 (48%), Gaps = 6/113 (5%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           CIFC I       +++YEDD+V  F DI P ++ H+L +P+ HI  ++ L    + L++ 
Sbjct: 8   CIFCKIIEGELPAKVVYEDDQVIAFEDIHPKAKIHLLLVPRSHISSLEQLEVKHEALISH 67

Query: 421 MMSISRELLSKNNLS------IEDARFGYHWPPFRSVKHLHLHTIAPESEMGF 561
           ++ +  +L  +  L       I   R G      + V HLH+H +      GF
Sbjct: 68  LLLLLPDLARRQGLQDGFRTIINTGRGG-----GQEVDHLHIHLLGGSQLPGF 115


>UniRef50_Q9BX68 Cluster: Histidine triad nucleotide-binding protein
           2; n=61; cellular organisms|Rep: Histidine triad
           nucleotide-binding protein 2 - Homo sapiens (Human)
          Length = 163

 Score = 59.7 bits (138), Expect = 6e-08
 Identities = 33/104 (31%), Positives = 52/104 (50%), Gaps = 6/104 (5%)
 Frame = +1

Query: 244 IFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRM 423
           IF  I +K    +ILYED +  VFRD+ P +  H L IPK+ I  +      D++LL  +
Sbjct: 55  IFSRILDKSLPADILYEDQQCLVFRDVAPQAPVHFLVIPKKPIPRISQAEEEDQQLLGHL 114

Query: 424 MSISRELLSKNNLS------IEDARFGYHWPPFRSVKHLHLHTI 537
           + ++++      L       I D + G      +SV HLH+H +
Sbjct: 115 LLVAKQTAKAEGLGDGYRLVINDGKLG-----AQSVYHLHIHVL 153


>UniRef50_Q2F5W9 Cluster: Protein kinase C inhibitor; n=3;
           Endopterygota|Rep: Protein kinase C inhibitor - Bombyx
           mori (Silk moth)
          Length = 162

 Score = 59.3 bits (137), Expect = 8e-08
 Identities = 37/106 (34%), Positives = 53/106 (50%)
 Frame = +1

Query: 244 IFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRM 423
           IF  I +K    +I+YEDD    F DI P +  H L IPKR I  ++   + D ELL  +
Sbjct: 55  IFDKIISKEIRADIIYEDDLCLAFNDIAPQAPVHFLVIPKRRIARLQDAENNDNELLGHL 114

Query: 424 MSISRELLSKNNLSIEDARFGYHWPPFRSVKHLHLHTIAPESEMGF 561
           M ++R L ++   S             +SV HLHLH +    +MG+
Sbjct: 115 MLVARSLGAQRAPSGWRLVVNNGKDGAQSVYHLHLHVLGGR-QMGW 159


>UniRef50_Q8F673 Cluster: HIT family hydrolase; n=6; cellular
           organisms|Rep: HIT family hydrolase - Leptospira
           interrogans
          Length = 122

 Score = 58.8 bits (136), Expect = 1e-07
 Identities = 30/102 (29%), Positives = 52/102 (50%), Gaps = 2/102 (1%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           CIFC I  K   +++++E+DE+  F DI P +  HI+ IPK+HI  +  + + D  LL  
Sbjct: 12  CIFCKIIRKEIPSKVVFENDEILAFYDISPQAPVHIVFIPKKHIPSLSEIENEDSHLLGN 71

Query: 421 MMSISRELLSKNNLSIEDARFGYHWPP--FRSVKHLHLHTIA 540
           ++   R+       +    R   +      ++V H+H H +A
Sbjct: 72  ILLQIRDTAKNLGFAENGYRVVNNTGKNGGQTVFHIHFHLLA 113


>UniRef50_Q1YR93 Cluster: Protein kinase C inhibitor; n=2;
           Gammaproteobacteria|Rep: Protein kinase C inhibitor -
           gamma proteobacterium HTCC2207
          Length = 120

 Score = 58.8 bits (136), Expect = 1e-07
 Identities = 36/104 (34%), Positives = 54/104 (51%), Gaps = 2/104 (1%)
 Frame = +1

Query: 244 IFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRM 423
           +F  I N+    EILYEDD+  V  DI P +  H+L IP++ I  +     ADK LL  +
Sbjct: 8   LFTRIINREIPAEILYEDDKCIVINDISPQAPIHMLVIPRQPIAKLADAIEADKALLGHL 67

Query: 424 MSISRELLSKNNLSIEDARFGYH--WPPFRSVKHLHLHTIAPES 549
           M ++ E+  +  +  E  R   +      ++V HLHLH +A  S
Sbjct: 68  MWVAGEVARQAGVE-EAFRLVVNNGRAAGQTVFHLHLHVLADPS 110


>UniRef50_A7HMY4 Cluster: Histidine triad (HIT) protein; n=2;
           Thermotogaceae|Rep: Histidine triad (HIT) protein -
           Fervidobacterium nodosum Rt17-B1
          Length = 111

 Score = 58.8 bits (136), Expect = 1e-07
 Identities = 29/109 (26%), Positives = 55/109 (50%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           C+FC I +    +E +YED++  V +DI+P +  H+L I K+HI  +  L+  D + + +
Sbjct: 4   CVFCKIIDGQIPSEKVYEDNDFIVIKDIRPVAPVHLLAIYKKHIATINDLSEEDSKNMWK 63

Query: 421 MMSISRELLSKNNLSIEDARFGYHWPPFRSVKHLHLHTIAPESEMGFIG 567
           +  + +++    NL              + V H+H H I    ++G +G
Sbjct: 64  LFEVIKKVTKDQNLESYRIVQNNGKDAGQEVHHIHFHIIGGR-KLGALG 111


>UniRef50_Q5TVU2 Cluster: ENSANGP00000027488; n=1; Anopheles gambiae
           str. PEST|Rep: ENSANGP00000027488 - Anopheles gambiae
           str. PEST
          Length = 121

 Score = 58.8 bits (136), Expect = 1e-07
 Identities = 26/77 (33%), Positives = 44/77 (57%)
 Frame = +1

Query: 316 RDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLSIEDARFGYHW 495
           RD+ P +R+H L +P+++I  +  LT  D  LL  M  +++ ++ +  L  +   FGYH 
Sbjct: 27  RDLYPKARYHFLVLPRKNINTLHELTIDDVALLKDMYGLAQSVIKEGGLDTKQFNFGYHL 86

Query: 496 PPFRSVKHLHLHTIAPE 546
            P   +K LHLH I+ +
Sbjct: 87  KP--HMKRLHLHVISKD 101


>UniRef50_A7A616 Cluster: Putative uncharacterized protein; n=2;
           Bifidobacterium adolescentis|Rep: Putative
           uncharacterized protein - Bifidobacterium adolescentis
           L2-32
          Length = 124

 Score = 58.4 bits (135), Expect = 1e-07
 Identities = 28/102 (27%), Positives = 49/102 (48%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           C+FC I      +E +YEDD    F+DI P ++ H+L +P++H  +V  L   D   L  
Sbjct: 19  CLFCKIIAGEIPSEKVYEDDATYAFKDINPKAKVHVLIVPRKHYANVAELAKEDPAQLAH 78

Query: 421 MMSISRELLSKNNLSIEDARFGYHWPPFRSVKHLHLHTIAPE 546
           M  +++++  +         F       ++V H+H H +  E
Sbjct: 79  MAEVAQKIADQEFHGAFRLIFNTGIDAGQTVFHVHAHVLTGE 120


>UniRef50_O07817 Cluster: Protein hitA; n=7; Betaproteobacteria|Rep:
           Protein hitA - Neisseria gonorrhoeae
          Length = 107

 Score = 58.4 bits (135), Expect = 1e-07
 Identities = 28/75 (37%), Positives = 41/75 (54%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           CIFC IA K    + +YED E+  F+DI PA+  H+L IPK H + +       + LL +
Sbjct: 4   CIFCKIAAKEIPAQTVYEDGEMVCFKDINPAAPLHLLLIPKVHFDSLAHAAPEHQPLLGK 63

Query: 421 MMSISRELLSKNNLS 465
           MM    E+   + L+
Sbjct: 64  MMLKVPEIAKASGLT 78


>UniRef50_Q7K6B1 Cluster: Protein kinase c inhibitor-like protein,
           putative; n=3; Plasmodium|Rep: Protein kinase c
           inhibitor-like protein, putative - Plasmodium falciparum
           (isolate 3D7)
          Length = 130

 Score = 58.0 bits (134), Expect = 2e-07
 Identities = 39/104 (37%), Positives = 57/104 (54%), Gaps = 5/104 (4%)
 Frame = +1

Query: 244 IFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSAD---KELL 414
           IF  IA      + +YEDD+V  F DI P +  HI+ IPKR  + +  L+ A+   KE+L
Sbjct: 21  IFGKIARGEVPVDAVYEDDKVIAFNDIYPQAPVHIIVIPKRR-DGLTRLSKAEEKHKEIL 79

Query: 415 NRMMSISRELLSKNNLSIEDARFGYHWPP--FRSVKHLHLHTIA 540
             +M    E++ KNNL   D R   +  P   +S+ +LHLH +A
Sbjct: 80  GHLMWAVAEIVRKNNLG--DFRLVVNNGPEACQSIYYLHLHILA 121


>UniRef50_UPI00015B4880 Cluster: PREDICTED: similar to FHA-HIT; n=1;
           Nasonia vitripennis|Rep: PREDICTED: similar to FHA-HIT -
           Nasonia vitripennis
          Length = 205

 Score = 57.6 bits (133), Expect = 3e-07
 Identities = 39/115 (33%), Positives = 60/115 (52%), Gaps = 4/115 (3%)
 Frame = +1

Query: 292 EDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLSIE 471
           EDD + V +D  P +RFH L +PK+ I  +  +T  D ELL  M +I+ + +  +    +
Sbjct: 48  EDDRIAVIKDKYPKARFHYLVLPKKDISTISEVTRDDIELLQHMENIANKFVDIH----K 103

Query: 472 DARF--GYHWPPFRSVKHLHLHTIAPESEMGFIGRVIFKKNSYW--FVSPEYVAS 624
           D  F  GYH  P  S+  LHLH I+ +    F  R + K   +W  F +P ++ S
Sbjct: 104 DYEFLVGYHAIP--SMHRLHLHVISTD----FDSRCL-KTKQHWNSFTTPYFLPS 151


>UniRef50_A3DF72 Cluster: Histidine triad (HIT) protein; n=2;
           Clostridium thermocellum|Rep: Histidine triad (HIT)
           protein - Clostridium thermocellum (strain ATCC 27405 /
           DSM 1237)
          Length = 114

 Score = 57.6 bits (133), Expect = 3e-07
 Identities = 23/58 (39%), Positives = 36/58 (62%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELL 414
           C+FC I  +   + I YED+ V   +DI PA+  H+L IPK HI +VK +  ++ ++L
Sbjct: 4   CVFCKIIKRELPSTIYYEDERVIAIKDINPAAPVHVLIIPKEHIANVKEINESNAQIL 61


>UniRef50_Q5Z134 Cluster: Putative uncharacterized protein; n=1;
           Nocardia farcinica|Rep: Putative uncharacterized protein
           - Nocardia farcinica
          Length = 150

 Score = 57.2 bits (132), Expect = 3e-07
 Identities = 34/104 (32%), Positives = 50/104 (48%), Gaps = 5/104 (4%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           C+FC I         +YED+ +C F DI+P +R H L IPKRH      L   D EL   
Sbjct: 8   CVFCRIVAGAAPATKVYEDETLCAFLDIRPIARGHTLVIPKRH---AAGLPDLDPELGAA 64

Query: 421 MMSISREL---LSKNNLSIEDARFGYH--WPPFRSVKHLHLHTI 537
           M   +  +   + +  L+ + A    +     F++V H+HLH I
Sbjct: 65  MFRAAHRIALAMRRGGLAADGANLVLNDGRAAFQTVGHVHLHVI 108


>UniRef50_Q74MW7 Cluster: NEQ519; n=1; Nanoarchaeum equitans|Rep:
           NEQ519 - Nanoarchaeum equitans
          Length = 129

 Score = 57.2 bits (132), Expect = 3e-07
 Identities = 34/106 (32%), Positives = 53/106 (50%), Gaps = 2/106 (1%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           CIFC I NK     I+YEDD V    DI P ++ H L IPK+H+  +K L+   +E   +
Sbjct: 2   CIFCKIINKEIPAYIVYEDDFVIAILDIYPMAKGHTLVIPKKHVTRLKELS---EEEAKK 58

Query: 421 MMSISRELLSKNNLSIEDARFGYHWPP--FRSVKHLHLHTIAPESE 552
           + +  ++++ K      D     +  P   + + HLH+H I    E
Sbjct: 59  LFAGLKKVIEKIEKISPDYNIIINQGPKAGQEIDHLHIHIIPRTGE 104


>UniRef50_P61799 Cluster: Aprataxin; n=21; Deuterostomia|Rep:
           Aprataxin - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 324

 Score = 57.2 bits (132), Expect = 3e-07
 Identities = 30/88 (34%), Positives = 50/88 (56%), Gaps = 1/88 (1%)
 Frame = +1

Query: 286 LYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSK-NNL 462
           +Y+DD V V +D  P +R+H L +P + I  +K+L S   ELL  M  ++ +++ +  + 
Sbjct: 164 VYKDDSVVVIKDKYPKARYHWLVLPWQSISSLKALRSEHVELLKHMQRVADQMVEQCPDA 223

Query: 463 SIEDARFGYHWPPFRSVKHLHLHTIAPE 546
                R GYH  P  S+ H+HLH I+ +
Sbjct: 224 HKLSFRLGYHAIP--SMSHVHLHVISQD 249


>UniRef50_P61802 Cluster: Aprataxin; n=1; Ciona intestinalis|Rep:
           Aprataxin - Ciona intestinalis (Transparent sea squirt)
          Length = 380

 Score = 56.8 bits (131), Expect = 4e-07
 Identities = 30/107 (28%), Positives = 58/107 (54%), Gaps = 2/107 (1%)
 Frame = +1

Query: 283 ILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLS--KN 456
           ++ ED+++ V +D  P +++H L +PK  I   K+L++ + ELL  ++ + +EL +  K+
Sbjct: 219 VVKEDEQIVVIKDKYPKAKYHWLILPKDSISSTKNLSTDNIELLKHILKVGQELAAEVKD 278

Query: 457 NLSIEDARFGYHWPPFRSVKHLHLHTIAPESEMGFIGRVIFKKNSYW 597
                + RFGYH     S+  +H+H I+ + +        FK   +W
Sbjct: 279 KQPDVEFRFGYH--AVASMSQMHMHVISQDFQSS-----SFKTKKHW 318


>UniRef50_Q4JN62 Cluster: Predicted protein kinase C inhibitor
           chPKCI; n=1; uncultured bacterium BAC13K9BAC|Rep:
           Predicted protein kinase C inhibitor chPKCI - uncultured
           bacterium BAC13K9BAC
          Length = 114

 Score = 56.4 bits (130), Expect = 6e-07
 Identities = 31/100 (31%), Positives = 51/100 (51%), Gaps = 1/100 (1%)
 Frame = +1

Query: 244 IFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLT-SADKELLNR 420
           +F  I NK   + I+YED    +  DI P +  H L IPK+ I+ +  L  + DK++L  
Sbjct: 6   VFQQIINKEIPSNIIYEDQLCIIIEDISPQAPIHYLAIPKKMIKGISDLNDNEDKDILGH 65

Query: 421 MMSISRELLSKNNLSIEDARFGYHWPPFRSVKHLHLHTIA 540
           MM   +  ++K N++             ++V HLH+H +A
Sbjct: 66  MMISIKNQMTKMNINDYRLVINNGSEAGQTVFHLHIHILA 105


>UniRef50_UPI000038E073 Cluster: hypothetical protein Faci_03000287;
           n=1; Ferroplasma acidarmanus fer1|Rep: hypothetical
           protein Faci_03000287 - Ferroplasma acidarmanus fer1
          Length = 137

 Score = 55.6 bits (128), Expect = 1e-06
 Identities = 32/100 (32%), Positives = 50/100 (50%), Gaps = 1/100 (1%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADK-ELLN 417
           CIFC+I N    +  +YE ++   F DI P S  HIL IPK H +D+  + S    E + 
Sbjct: 2   CIFCDIVNDKVKSHKIYETNKTLAFLDIHPISNGHILVIPKEHYKDIYEMDSNILIETIK 61

Query: 418 RMMSISRELLSKNNLSIEDARFGYHWPPFRSVKHLHLHTI 537
            + +I+  L  K N++  +          ++V H H+H I
Sbjct: 62  TVKAITGILKDKLNINAVNIMNSNGEIANQTVFHYHIHVI 101


>UniRef50_A7H6R9 Cluster: Histidine triad (HIT) protein; n=14;
           Bacteria|Rep: Histidine triad (HIT) protein -
           Anaeromyxobacter sp. Fw109-5
          Length = 114

 Score = 55.6 bits (128), Expect = 1e-06
 Identities = 25/101 (24%), Positives = 48/101 (47%), Gaps = 2/101 (1%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           C+FC I  K    +I++ED +   F D+ P +  H+L +P++H+  +  L   D  L+ +
Sbjct: 4   CLFCKIVAKTLPAKIVHEDADTVAFEDLNPQAPTHVLIVPRKHVATMVDLAPEDDALVGK 63

Query: 421 MMSISRELLSKNNLSIEDAR--FGYHWPPFRSVKHLHLHTI 537
           +      +     +     R    ++    +SV H+HLH +
Sbjct: 64  LFRAGAAIAKARGIDGPGYRVVMNHNRDAGQSVFHIHLHVL 104


>UniRef50_Q7PTZ0 Cluster: ENSANGP00000012901; n=2; Anopheles gambiae
           str. PEST|Rep: ENSANGP00000012901 - Anopheles gambiae
           str. PEST
          Length = 130

 Score = 55.6 bits (128), Expect = 1e-06
 Identities = 28/87 (32%), Positives = 45/87 (51%)
 Frame = +1

Query: 286 LYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLS 465
           L+  D   V +D  P +  H L +P + I+ V  L+S D  LL  M  +  + +    L+
Sbjct: 21  LFVSDLAVVIKDKYPKALHHFLVLPWKDIDSVYDLSSDDDGLLQNMYELGLKAIGTTGLT 80

Query: 466 IEDARFGYHWPPFRSVKHLHLHTIAPE 546
           ++   FGYH  P  S++ LHLH I+ +
Sbjct: 81  VDRFDFGYHMKP--SMRRLHLHVISKD 105


>UniRef50_Q8PVK5 Cluster: Hit-like protein; n=4;
           Methanosarcinaceae|Rep: Hit-like protein -
           Methanosarcina mazei (Methanosarcina frisia)
          Length = 155

 Score = 55.6 bits (128), Expect = 1e-06
 Identities = 34/103 (33%), Positives = 51/103 (49%), Gaps = 4/103 (3%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           C+FC I +    ++ +YEDD VC F DI PAS  H L  PK+H     S T    E   R
Sbjct: 9   CLFCKIISGEIPSKKVYEDDAVCAFLDIYPASEGHTLIAPKKHF---NSFTDMGAEDTAR 65

Query: 421 MMSISRELLS--KNNLSIEDARFGYHWPPF--RSVKHLHLHTI 537
           +   +R++ +  +   S E +  G +      + V H+H+H I
Sbjct: 66  LFEAARKITAAVEKAFSAEGSNIGINNGEVAGQEVPHVHVHVI 108


>UniRef50_Q58276 Cluster: Uncharacterized HIT-like protein MJ0866;
           n=1; Methanocaldococcus jannaschii|Rep: Uncharacterized
           HIT-like protein MJ0866 - Methanococcus jannaschii
          Length = 129

 Score = 55.2 bits (127), Expect = 1e-06
 Identities = 32/101 (31%), Positives = 48/101 (47%), Gaps = 2/101 (1%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           CIFC I N     +++YED+ V  F DI P ++ H L +PK+H E    +   D EL N 
Sbjct: 2   CIFCKIINGEIPAKVVYEDEHVLAFLDINPRNKGHTLVVPKKHYERFDEM--PDDELCNF 59

Query: 421 MMSISR--ELLSKNNLSIEDARFGYHWPPFRSVKHLHLHTI 537
           +  + +  E+L K      +          + V H+H H I
Sbjct: 60  IKGVKKTVEVLKKLGFDGYNIVNNNGRVAGQEVNHVHFHII 100


>UniRef50_UPI0000D555E3 Cluster: PREDICTED: similar to Hypothetical
           HIT-like protein F21C3.3; n=3; Coelomata|Rep: PREDICTED:
           similar to Hypothetical HIT-like protein F21C3.3 -
           Tribolium castaneum
          Length = 156

 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 35/103 (33%), Positives = 54/103 (52%), Gaps = 5/103 (4%)
 Frame = +1

Query: 244 IFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADK----EL 411
           IF  I +K    +I+YEDD+   F D+ P +  H L IPK+ I  + S+  +DK    EL
Sbjct: 49  IFDKIISKEIPADIIYEDDKCLAFNDVNPQAPVHFLVIPKQRIPMLDSVKDSDKDIMAEL 108

Query: 412 LNRMMSISRELLSKN-NLSIEDARFGYHWPPFRSVKHLHLHTI 537
           + R   +++E L     L I + + G      +SV HLH+H +
Sbjct: 109 VLRAQKLAKERLPNGYRLVINNGKQG-----CQSVYHLHIHIL 146


>UniRef50_Q5K261 Cluster: Putative uncharacterized protein pkci;
           n=3; cellular organisms|Rep: Putative uncharacterized
           protein pkci - Guillardia theta (Cryptomonas phi)
          Length = 181

 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 30/101 (29%), Positives = 54/101 (53%), Gaps = 2/101 (1%)
 Frame = +1

Query: 244 IFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRH--IEDVKSLTSADKELLN 417
           IF  I  K   +++++EDD+V VF+DI P +  H+L IPKR   +  ++  T+  + +L 
Sbjct: 72  IFDKIVAKSIPSQVVFEDDKVLVFKDINPQAPTHLLVIPKRRETLSQLRFATAEHEGILG 131

Query: 418 RMMSISRELLSKNNLSIEDARFGYHWPPFRSVKHLHLHTIA 540
            M+++  ++ S+  L              + V HLH+H +A
Sbjct: 132 HMLAVVAKVASEEGLGDYRLVVNDGRGAGQEVFHLHMHVLA 172


>UniRef50_Q6MTB0 Cluster: Histidine triad protein; n=2;
           Mycoplasma|Rep: Histidine triad protein - Mycoplasma
           mycoides subsp. mycoides SC
          Length = 132

 Score = 54.4 bits (125), Expect = 2e-06
 Identities = 33/113 (29%), Positives = 57/113 (50%), Gaps = 5/113 (4%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           C+FC I N+   +  +YE++ V  F D++P S  H+L IPK+H E   + ++ D + L  
Sbjct: 3   CLFCKIINQEIPSYKIYENEYVYSFLDVRPVSNGHLLIIPKKHFE---NFSACDDKYLQE 59

Query: 421 MMSISRELLSKNNLSIEDARFGY----HWPPFRSVKHLHLHTIAP-ESEMGFI 564
           ++   + L++     +  A F Y         ++V H H H +   E E GF+
Sbjct: 60  VILAKKHLVNLLKEKLNPAGFNYLSNEQAISGQTVLHYHEHIMPKYEKEKGFL 112


>UniRef50_Q9HIK0 Cluster: Cell-cycle regulation histidine triad
           (HIT) related protein; n=2; Thermoplasma|Rep: Cell-cycle
           regulation histidine triad (HIT) related protein -
           Thermoplasma acidophilum
          Length = 160

 Score = 53.6 bits (123), Expect = 4e-06
 Identities = 31/119 (26%), Positives = 58/119 (48%), Gaps = 1/119 (0%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           C FC+I +    +EI+Y D+    F D KP  + H L +P++H  D+ ++   D  L   
Sbjct: 20  CKFCDIISGKTASEIVYSDENFVAFLDYKPLFKGHTLLVPRKHFADIYAMD--DLTLSKM 77

Query: 421 MMSISRELLSKNNLSIEDARF-GYHWPPFRSVKHLHLHTIAPESEMGFIGRVIFKKNSY 594
           M +++   ++    +  D  F   +    +SV H+H+H +  + + G  G   + + SY
Sbjct: 78  MKTVTIISMAVERATGSDGTFIAINNKVSQSVPHVHVHIVPRKHKDGLKG-FFWPRQSY 135


>UniRef50_A3HAI2 Cluster: Histidine triad (HIT) protein; n=2;
           Thermoprotei|Rep: Histidine triad (HIT) protein -
           Caldivirga maquilingensis IC-167
          Length = 151

 Score = 53.6 bits (123), Expect = 4e-06
 Identities = 33/104 (31%), Positives = 54/104 (51%), Gaps = 5/104 (4%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           CIFC I  +     ++YEDD+V    D  P ++ HIL +PKRH  D+  +     E L +
Sbjct: 4   CIFCRIIGREAPGHVVYEDDDVIAILDKYPINKGHILVMPKRHYRDIFEI---PPEALCK 60

Query: 421 MMSISRELLSK---NNLSIEDARFGYHWPPF--RSVKHLHLHTI 537
           +M +++ L+++   N L  +  R   +  P   + V H H+H I
Sbjct: 61  VMKVAK-LMARAVVNGLKADGVRLIQNNGPSAGQVVFHFHVHVI 103


>UniRef50_P0ACE9 Cluster: HIT-like protein ycfF; n=109;
           Bacteria|Rep: HIT-like protein ycfF - Shigella flexneri
          Length = 119

 Score = 53.2 bits (122), Expect = 5e-06
 Identities = 28/100 (28%), Positives = 54/100 (54%), Gaps = 2/100 (2%)
 Frame = +1

Query: 244 IFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRM 423
           IF  I  +   ++I+Y+DD V  FRDI P +  HIL IP   I  V  +++  ++ L RM
Sbjct: 6   IFSKIIRREIPSDIVYQDDLVTAFRDISPQAPTHILIIPNILIPTVNDVSAEHEQALGRM 65

Query: 424 MSISRELLSKNNLSIEDAR--FGYHWPPFRSVKHLHLHTI 537
           ++++ ++  +  ++ +  R     +    + V H+H+H +
Sbjct: 66  ITVAAKIAEQEGIAEDGYRLIMNTNRHGGQEVYHIHMHLL 105


>UniRef50_P32084 Cluster: Uncharacterized HIT-like protein
           Synpcc7942_1390; n=22; cellular organisms|Rep:
           Uncharacterized HIT-like protein Synpcc7942_1390 -
           Synechococcus sp. (strain PCC 7942) (Anacystis nidulans
           R2)
          Length = 114

 Score = 53.2 bits (122), Expect = 5e-06
 Identities = 32/104 (30%), Positives = 54/104 (51%), Gaps = 2/104 (1%)
 Frame = +1

Query: 244 IFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRM 423
           IF  I  +    +I+YEDD    FRD+ P +  HIL IPK+ I ++   T+  + LL  +
Sbjct: 6   IFGKIIRREIPADIVYEDDLCLAFRDVAPQAPVHILVIPKQPIANLLEATAEHQALLGHL 65

Query: 424 MSISRELLSKNNLSIEDARFGYHWPPF--RSVKHLHLHTIAPES 549
           +   + + ++  L+ E  R   +  P   ++V HLH+H +   S
Sbjct: 66  LLTVKAIAAQEGLT-EGYRTVINTGPAGGQTVYHLHIHLLGGRS 108


>UniRef50_A7FTJ1 Cluster: HIT family protein; n=4; Clostridium
           botulinum|Rep: HIT family protein - Clostridium
           botulinum (strain ATCC 19397 / Type A)
          Length = 142

 Score = 52.8 bits (121), Expect = 7e-06
 Identities = 30/99 (30%), Positives = 48/99 (48%), Gaps = 2/99 (2%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           C FC I NK +   I+Y++D VC F   +P +  H+L  PK+H  D   L   D E    
Sbjct: 8   CNFCKIINKEKKANIVYQNDLVCCFLAEEPINEGHMLIAPKKHYLD---LDQMDDETAIE 64

Query: 421 MMSISRELLS--KNNLSIEDARFGYHWPPFRSVKHLHLH 531
           +M +S+ ++   K+    +      +   F +V H H+H
Sbjct: 65  IMKVSKIMVKVLKDTYKSDGYSIMQNGGSFNNVGHYHMH 103


>UniRef50_P49773 Cluster: Histidine triad nucleotide-binding protein
           1; n=46; cellular organisms|Rep: Histidine triad
           nucleotide-binding protein 1 - Homo sapiens (Human)
          Length = 126

 Score = 52.8 bits (121), Expect = 7e-06
 Identities = 31/100 (31%), Positives = 49/100 (49%), Gaps = 2/100 (2%)
 Frame = +1

Query: 244 IFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRM 423
           IF  I  K    +I++EDD    F DI P +  H L IPK+HI  +      D+ LL  +
Sbjct: 18  IFGKIIRKEIPAKIIFEDDRCLAFHDISPQAPTHFLVIPKKHISQISVAEDDDESLLGHL 77

Query: 424 MSISRELLSKNNLSIEDARFGYH--WPPFRSVKHLHLHTI 537
           M + ++  +   L+ +  R   +      +SV H+HLH +
Sbjct: 78  MIVGKKCAADLGLN-KGYRMVVNEGSDGGQSVYHVHLHVL 116


>UniRef50_UPI000155CE00 Cluster: PREDICTED: similar to aprataxin;
           n=1; Ornithorhynchus anatinus|Rep: PREDICTED: similar to
           aprataxin - Ornithorhynchus anatinus
          Length = 408

 Score = 52.4 bits (120), Expect = 1e-05
 Identities = 28/89 (31%), Positives = 53/89 (59%), Gaps = 2/89 (2%)
 Frame = +1

Query: 286 LYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLS 465
           +Y+D++V V +D  P +R H L +P   I  ++++T    ELL  M ++ ++ L+++ + 
Sbjct: 194 VYKDEKVVVIKDKYPKARNHWLVLPWESIASLRAVTREHLELLKHMQAVGKK-LTQDCID 252

Query: 466 IEDARF--GYHWPPFRSVKHLHLHTIAPE 546
            +  +F  GYH  P  S+ H+HLH I+ +
Sbjct: 253 SDRLQFRMGYHAIP--SMSHIHLHVISQD 279


>UniRef50_Q4LEG8 Cluster: Histidine triad protein; n=1; uncultured
           crenarchaeote 45-H-12|Rep: Histidine triad protein -
           uncultured crenarchaeote 45-H-12
          Length = 161

 Score = 52.4 bits (120), Expect = 1e-05
 Identities = 28/100 (28%), Positives = 47/100 (47%), Gaps = 1/100 (1%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           C+FC I        ++YEDD + VF D  P S  H L IPKRH   +  + S D  +L  
Sbjct: 15  CVFCLIVEGKRDAAVVYEDDAMMVFMDKYPISNGHTLVIPKRHYTTILDMESRDVGMLFA 74

Query: 421 MM-SISRELLSKNNLSIEDARFGYHWPPFRSVKHLHLHTI 537
           ++  +++ +++  N               + V H+H+H +
Sbjct: 75  LVHKVAKAVVNALNAQGFSIAQNNGKVAHQVVPHVHVHIV 114


>UniRef50_Q2LVF0 Cluster: Hit family hydrolase; n=1; Syntrophus
           aciditrophicus SB|Rep: Hit family hydrolase - Syntrophus
           aciditrophicus (strain SB)
          Length = 116

 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 27/101 (26%), Positives = 47/101 (46%), Gaps = 2/101 (1%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           C+FC+I         +YEDD V  F DI P +  H++ +PKRHI     ++      L  
Sbjct: 5   CLFCSIVKGEIPCARIYEDDHVLAFEDIHPMAPVHVVVVPKRHISTFMDVSDDTMAYLMS 64

Query: 421 MMSISRELLSKNNLSIEDAR--FGYHWPPFRSVKHLHLHTI 537
           MM+ ++++     +  +  R          + + HLH+H +
Sbjct: 65  MMTAAQKIAKLKAIDEKGFRTVINCKEEGGQVIFHLHMHLL 105


>UniRef50_Q558W0 Cluster: Putative uncharacterized protein; n=3;
           Dictyostelium discoideum|Rep: Putative uncharacterized
           protein - Dictyostelium discoideum AX4
          Length = 390

 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 37/125 (29%), Positives = 59/125 (47%), Gaps = 8/125 (6%)
 Frame = +1

Query: 247 FCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMM 426
           FCN         +LY DD+     D  P ++ H L IP+  I  +  LT +   +L  M 
Sbjct: 233 FCNKPESFLDV-VLYYDDKTVAVLDKYPKAKHHYLVIPRVEINTLDELTPSFIPMLEHMY 291

Query: 427 SIS----RELLSK----NNLSIEDARFGYHWPPFRSVKHLHLHTIAPESEMGFIGRVIFK 582
           +++     E++SK    +NL   D + G+H  P  S+K LHLH I+ +    ++     K
Sbjct: 292 NVADAIINEIISKDNDDDNLKKSDFKLGFHAIP--SMKRLHLHIISNDYNTKYL-----K 344

Query: 583 KNSYW 597
            N +W
Sbjct: 345 NNKHW 349


>UniRef50_A0BUI5 Cluster: Chromosome undetermined scaffold_129,
           whole genome shotgun sequence; n=1; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_129,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 117

 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 32/111 (28%), Positives = 55/111 (49%), Gaps = 5/111 (4%)
 Frame = +1

Query: 244 IFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRM 423
           +F  I  +    +I+YED     F DI P ++ H+L IPK H++ + + +     LL  +
Sbjct: 11  VFEKIIKRQIPAKIIYEDKHCLAFEDINPKAKVHVLVIPKEHLDRLSNASEQHINLLGNL 70

Query: 424 M----SISREL-LSKNNLSIEDARFGYHWPPFRSVKHLHLHTIAPESEMGF 561
           M     + ++L L    + I D + G      ++V HLH H ++ E+  GF
Sbjct: 71  MYAVNRVGKQLQLEGYRVIINDGQKG-----GQTVFHLHAHILSGENLTGF 116


>UniRef50_P94252 Cluster: Uncharacterized HIT-like protein BB_0379;
           n=4; Borrelia burgdorferi group|Rep: Uncharacterized
           HIT-like protein BB_0379 - Borrelia burgdorferi (Lyme
           disease spirochete)
          Length = 139

 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 39/113 (34%), Positives = 52/113 (46%), Gaps = 6/113 (5%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           CIFC I NK   +  +YEDD V  F DI P +  H L IPK H E   SL + D +   R
Sbjct: 4   CIFCKIINKELPSYKVYEDDLVLAFLDINPLTVGHTLVIPKEHSE---SLLNMDDKFNER 60

Query: 421 MMSISREL---LSKNNLSIEDARFGYH---WPPFRSVKHLHLHTIAPESEMGF 561
           ++ + +++   L + N SI      Y        + V H H H I      GF
Sbjct: 61  VLKVCKKISNALKRINSSIYGGINIYSALGAGAGQEVFHTHFHVIPRFKNDGF 113


>UniRef50_Q1MR92 Cluster: 141aa long hypothetical histidine triad
           nucleotide-binding protein; n=1; Lawsonia
           intracellularis PHE/MN1-00|Rep: 141aa long hypothetical
           histidine triad nucleotide-binding protein - Lawsonia
           intracellularis (strain PHE/MN1-00)
          Length = 146

 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 36/121 (29%), Positives = 54/121 (44%), Gaps = 3/121 (2%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSL-TSADKELLN 417
           CIFCNI  K      +Y  D      DI P ++ H L +P +H+E +  +  S   +LL+
Sbjct: 9   CIFCNIIQKKIPCVSIYNSDNFIALLDINPVNKGHTLIVPTQHVETMFDIDPSLGTDLLS 68

Query: 418 RMMSISRELLSKNNLSIEDARFGYHWPPFRSVKHLHLHTIAPESEMGFIG--RVIFKKNS 591
            M  I   ++   N    +     +    + V HLH H I P     FIG  R+ ++K  
Sbjct: 69  IMQHIGPAIMKATNAEGVNVIQNNYVAAGQEVPHLHWH-IIPR----FIGDSRIRWEKGK 123

Query: 592 Y 594
           Y
Sbjct: 124 Y 124


>UniRef50_Q7Z2E3 Cluster: Aprataxin; n=44; Euteleostomi|Rep:
           Aprataxin - Homo sapiens (Human)
          Length = 356

 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 28/88 (31%), Positives = 48/88 (54%), Gaps = 1/88 (1%)
 Frame = +1

Query: 286 LYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRE-LLSKNNL 462
           +Y+D++V V +D  P +R+H L +P   I  +K++     ELL  M ++  + ++     
Sbjct: 196 VYKDEQVVVIKDKYPKARYHWLVLPWTSISSLKAVAREHLELLKHMHTVGEKVIVDFAGS 255

Query: 463 SIEDARFGYHWPPFRSVKHLHLHTIAPE 546
           S    R GYH  P  S+ H+HLH I+ +
Sbjct: 256 SKLRFRLGYHAIP--SMSHVHLHVISQD 281


>UniRef50_Q67LQ3 Cluster: HIT family protein; n=1; Symbiobacterium
           thermophilum|Rep: HIT family protein - Symbiobacterium
           thermophilum
          Length = 339

 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 26/62 (41%), Positives = 36/62 (58%), Gaps = 1/62 (1%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTS-ADKELLN 417
           C+FC IA   E + + YED     F +I+ A+  H+L IPKRH+E V  L S  D +L  
Sbjct: 201 CLFCRIATGGEASRV-YEDPYTLAFMNIRQANPGHVLVIPKRHVEQVFDLDSDLDSDLAG 259

Query: 418 RM 423
           R+
Sbjct: 260 RL 261


>UniRef50_A1SHY4 Cluster: Histidine triad (HIT) protein precursor;
           n=4; Actinobacteridae|Rep: Histidine triad (HIT) protein
           precursor - Nocardioides sp. (strain BAA-499 / JS614)
          Length = 112

 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 27/101 (26%), Positives = 49/101 (48%), Gaps = 1/101 (0%)
 Frame = +1

Query: 241 CIFCNI-ANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLN 417
           C+FC I A  + G E+++  +    FRDI P +  H+L +P+ H  +   L +AD +   
Sbjct: 4   CLFCKIVAGDIPG-EVVHTTERTVAFRDIDPKAPTHVLVVPRDHYTNAAELAAADPQATA 62

Query: 418 RMMSISRELLSKNNLSIEDARFGYHWPPFRSVKHLHLHTIA 540
            +++ +  + +    +     F       +SV H HLH +A
Sbjct: 63  ELVTTAAAVAAAEGYADYRIVFNTGAEAGQSVFHTHLHLLA 103


>UniRef50_Q970Y2 Cluster: 141aa long hypothetical histidine triad
           nucleotide-binding protein; n=1; Sulfolobus
           tokodaii|Rep: 141aa long hypothetical histidine triad
           nucleotide-binding protein - Sulfolobus tokodaii
          Length = 141

 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 30/102 (29%), Positives = 50/102 (49%), Gaps = 3/102 (2%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           CIFC I      ++ +YED E+  F DI P ++ H+L IPK H E++       KE L +
Sbjct: 6   CIFCKIVKGEIKSQKVYEDQEIMAFLDINPVNKGHVLVIPKDHYENI---FDVPKEKLGK 62

Query: 421 MMSISREL---LSKNNLSIEDARFGYHWPPFRSVKHLHLHTI 537
           ++ + +++   L K      +          + + HLH+H I
Sbjct: 63  VIEVVQKVAIALRKMGADGVNIVSNNGKAAEQHIFHLHIHVI 104


>UniRef50_A4FZK6 Cluster: Histidine triad (HIT) protein; n=5;
           Methanococcus|Rep: Histidine triad (HIT) protein -
           Methanococcus maripaludis
          Length = 130

 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 34/110 (30%), Positives = 48/110 (43%), Gaps = 3/110 (2%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           CIFC+I        I+YEDD+   F D  P +  H L IPK H E    L    KEL   
Sbjct: 2   CIFCDIVKGDIPARIIYEDDKFLAFMDAFPRAVGHTLIIPKEHFETFDEL---PKELACE 58

Query: 421 MMSISRELLSK-NNLSIEDARF--GYHWPPFRSVKHLHLHTIAPESEMGF 561
           MM++  +++ K   L ++             + V H+H H I      G+
Sbjct: 59  MMAVIHKIVKKLEKLEMDGYNLLNNNKQVSGQEVPHVHFHIIPRYENEGY 108


>UniRef50_UPI000050FA96 Cluster: COG0537: Diadenosine tetraphosphate
           (Ap4A) hydrolase and other HIT family hydrolases; n=1;
           Brevibacterium linens BL2|Rep: COG0537: Diadenosine
           tetraphosphate (Ap4A) hydrolase and other HIT family
           hydrolases - Brevibacterium linens BL2
          Length = 134

 Score = 50.8 bits (116), Expect = 3e-05
 Identities = 29/97 (29%), Positives = 52/97 (53%), Gaps = 1/97 (1%)
 Frame = +1

Query: 244 IFCNIAN-KLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           IF  I N ++ GT  +Y+DD    F D+ P +  H + +P+   E++     AD++LL+ 
Sbjct: 4   IFTKIINGEIPGT-FVYQDDLCVAFLDVSPMTEGHTMVVPR---EEISHWIDADQDLLDH 59

Query: 421 MMSISRELLSKNNLSIEDARFGYHWPPFRSVKHLHLH 531
           +M++SR++      + +  R G     +  V HLH+H
Sbjct: 60  LMAVSRKVGRAQQEAFDCERIGVMIQGY-EVPHLHIH 95


>UniRef50_A5GQU3 Cluster: HIT family hydrolase; n=10; Bacteria|Rep:
           HIT family hydrolase - Synechococcus sp. (strain RCC307)
          Length = 234

 Score = 50.4 bits (115), Expect = 4e-05
 Identities = 24/86 (27%), Positives = 44/86 (51%)
 Frame = +1

Query: 280 EILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNN 459
           E ++ED+    F DI+P +  H+L IP++HI  +K    +D  LL  ++ ++ ++  +  
Sbjct: 139 ERIHEDEHCIAFADIQPQAPVHLLVIPRQHIPSLKEAQPSDSALLGHLLLVAAKVAKEAG 198

Query: 460 LSIEDARFGYHWPPFRSVKHLHLHTI 537
           L              ++V HLH+H I
Sbjct: 199 LQDWRTVINTGAEAGQTVFHLHVHVI 224


>UniRef50_A0W3X6 Cluster: Histidine triad (HIT) protein; n=3;
           Bacteria|Rep: Histidine triad (HIT) protein - Geobacter
           lovleyi SZ
          Length = 114

 Score = 50.4 bits (115), Expect = 4e-05
 Identities = 30/101 (29%), Positives = 48/101 (47%), Gaps = 1/101 (0%)
 Frame = +1

Query: 247 FCN-IANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRM 423
           +C+ I   L    +  ++D V  F    P    H++ +PKRHIE + SL  +D ELL  +
Sbjct: 9   YCDKILKGLLEVPVYLQNDRVFAFYHTNPLWEHHVVLLPKRHIESLISLEESDNELLLEL 68

Query: 424 MSISRELLSKNNLSIEDARFGYHWPPFRSVKHLHLHTIAPE 546
           M  ++ + +         R   +   ++S KHLH H  A E
Sbjct: 69  MRTAKLIAADFMARFGACRVYTNLGTYQSSKHLHWHIGAGE 109


>UniRef50_A7AQA5 Cluster: HIT domain containing protein; n=1;
           Babesia bovis|Rep: HIT domain containing protein -
           Babesia bovis
          Length = 180

 Score = 50.4 bits (115), Expect = 4e-05
 Identities = 28/87 (32%), Positives = 42/87 (48%), Gaps = 2/87 (2%)
 Frame = +1

Query: 286 LYEDDEVCVFRDIKPASRFHILTIPKRH--IEDVKSLTSADKELLNRMMSISRELLSKNN 459
           +YED+ +  F DIKP +  H L IPKRH  +  + + T A  ++L  MM    E+    N
Sbjct: 85  VYEDEHILAFHDIKPVAPVHFLVIPKRHAGLTRLSNATDAHAKILGYMMVKVAEITRSLN 144

Query: 460 LSIEDARFGYHWPPFRSVKHLHLHTIA 540
           +              + + HLH+H IA
Sbjct: 145 IGDYRLVINDGAGAGQQIFHLHMHVIA 171


>UniRef50_Q11066 Cluster: Uncharacterized HIT-like protein
           Rv1262c/MT1300; n=17; Mycobacterium|Rep: Uncharacterized
           HIT-like protein Rv1262c/MT1300 - Mycobacterium
           tuberculosis
          Length = 144

 Score = 50.4 bits (115), Expect = 4e-05
 Identities = 35/112 (31%), Positives = 52/112 (46%), Gaps = 9/112 (8%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           C+FC I         +YED       DI+P +R H L +PKRH  D   LT    E L  
Sbjct: 3   CVFCAIIAGEAPAIRIYEDGGYLAILDIRPFTRGHTLVLPKRHTVD---LTDTPPEALAD 59

Query: 421 MMSISR---------ELLSKNNLSIEDARFGYHWPPFRSVKHLHLHTIAPES 549
           M++I +         +L    +++I D R       F++V H+HLH + P +
Sbjct: 60  MVAIGQRIARAARATKLADATHIAINDGR-----AAFQTVFHVHLHVLPPRN 106


>UniRef50_Q023M8 Cluster: Histidine triad (HIT) protein; n=2;
           Bacteria|Rep: Histidine triad (HIT) protein - Solibacter
           usitatus (strain Ellin6076)
          Length = 146

 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 31/111 (27%), Positives = 52/111 (46%), Gaps = 2/111 (1%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           C+FC IA       ++YE +E+  F D +P    H L IP+ H E   +LT   ++ +  
Sbjct: 10  CVFCQIAAGTLPAAVVYETEELVAFLDTRPLFPGHCLLIPRPHFE---TLTELPEDRVTP 66

Query: 421 MMSISRELLS--KNNLSIEDARFGYHWPPFRSVKHLHLHTIAPESEMGFIG 567
           + + +R L S  +     E +    +    +SV HLH+H +    + G  G
Sbjct: 67  LFAAARMLTSAVETAFDAEGSFVAINNRVSQSVPHLHVHIVPRRRKDGLKG 117


>UniRef50_A4F9S9 Cluster: Protein kinase C inhibitor; n=3;
           Actinomycetales|Rep: Protein kinase C inhibitor -
           Saccharopolyspora erythraea (strain NRRL 23338)
          Length = 123

 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 25/98 (25%), Positives = 47/98 (47%), Gaps = 2/98 (2%)
 Frame = +1

Query: 280 EILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNN 459
           +++ E D V   RDI P +  H+L +PK    +   L + D +LL  ++ ++ E+     
Sbjct: 21  DVVRETDRVIAIRDINPQAPTHVLVVPKTRYRNAAELAAKDPDLLAEVVRVAGEVAESEG 80

Query: 460 LSIEDAR--FGYHWPPFRSVKHLHLHTIAPESEMGFIG 567
           ++    R  F  +    +++ H+HLH +  E   G  G
Sbjct: 81  IAESGYRLLFNTNSDAGQTIFHVHLHLLGGERMGGLTG 118


>UniRef50_A1G4L9 Cluster: Histidine triad (HIT) protein; n=3;
           Bacteria|Rep: Histidine triad (HIT) protein -
           Salinispora arenicola CNS205
          Length = 113

 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 22/83 (26%), Positives = 44/83 (53%)
 Frame = +1

Query: 283 ILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNL 462
           ++ E ++V  F   +P    HI+ +PKRH+  +  L  A ++LL+R++ + R++ ++   
Sbjct: 19  VVVETEDVLAFEHTRPFWPVHIVVVPKRHVPSLVDLGDASRDLLHRVIEVVRQVAARVER 78

Query: 463 SIEDARFGYHWPPFRSVKHLHLH 531
                R   +   ++  KHLH H
Sbjct: 79  EQGACRVLTNLGRYQDSKHLHFH 101


>UniRef50_Q5TX49 Cluster: ENSANGP00000029056; n=1; Anopheles gambiae
           str. PEST|Rep: ENSANGP00000029056 - Anopheles gambiae
           str. PEST
          Length = 153

 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 31/100 (31%), Positives = 50/100 (50%), Gaps = 2/100 (2%)
 Frame = +1

Query: 244 IFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRM 423
           IF  I  K    +++YED++   F D+ P +  H L IPK  I+ +++ T    ELL  +
Sbjct: 46  IFDKIIKKQIPADVIYEDEKCIAFNDVAPQAPVHFLVIPKNKIDKLENSTPNQTELLGHL 105

Query: 424 MSISREL-LSKNNLSIE-DARFGYHWPPFRSVKHLHLHTI 537
           + ++ +L  SK           G H    ++V H+HLH I
Sbjct: 106 LHVAGQLGKSKAPKGFRLVINNGDH--GCQTVYHIHLHVI 143


>UniRef50_Q65J74 Cluster: Putative uncharacterized protein; n=1;
           Bacillus licheniformis ATCC 14580|Rep: Putative
           uncharacterized protein - Bacillus licheniformis (strain
           DSM 13 / ATCC 14580)
          Length = 142

 Score = 49.6 bits (113), Expect = 7e-05
 Identities = 27/101 (26%), Positives = 46/101 (45%), Gaps = 2/101 (1%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTS--ADKELL 414
           CIFC I ++   +  +Y+ D V  F DI P +  H L IP +HIE +  +       E++
Sbjct: 8   CIFCEIVSRKISSFEVYKTDYVTAFLDINPVTNGHTLIIPNKHIERLDHINDPHLSNEIM 67

Query: 415 NRMMSISRELLSKNNLSIEDARFGYHWPPFRSVKHLHLHTI 537
           + ++ + + L+                   + +KHLH H I
Sbjct: 68  DSLIKVPQLLIQSGICDDYTILSDNGHFAQQDIKHLHFHVI 108


>UniRef50_Q4K6N7 Cluster: HIT family protein; n=1; Pseudomonas
           fluorescens Pf-5|Rep: HIT family protein - Pseudomonas
           fluorescens (strain Pf-5 / ATCC BAA-477)
          Length = 158

 Score = 49.6 bits (113), Expect = 7e-05
 Identities = 29/116 (25%), Positives = 52/116 (44%), Gaps = 4/116 (3%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           CIFC IA       ++Y D+    F D+ P    H+L IP++H+E ++ L    ++ L +
Sbjct: 3   CIFCQIAAGTLPAALVYRDEHCMAFMDVHPLGEGHLLLIPQQHVEKLEQLPGFIRQHLYQ 62

Query: 421 MMSISRELLSKNNLSIEDARFGYH--WPPFRSVKHLHLHTIAPE--SEMGFIGRVI 576
           +         +    +E      +      + + H HLH I  +    +GF GR++
Sbjct: 63  VFDGLLAAQRRAGYGVEGTHLLVNDGRATNQHIPHAHLHLIPRKRGDGLGFAGRLL 118


>UniRef50_A0LM74 Cluster: Histidine triad (HIT) protein; n=1;
           Syntrophobacter fumaroxidans MPOB|Rep: Histidine triad
           (HIT) protein - Syntrophobacter fumaroxidans (strain DSM
           10017 / MPOB)
          Length = 136

 Score = 49.6 bits (113), Expect = 7e-05
 Identities = 31/108 (28%), Positives = 44/108 (40%), Gaps = 1/108 (0%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKE-LLN 417
           CIFC I         +YEDD V  F DI P +R H L +PKRH   +  +   D E  + 
Sbjct: 4   CIFCQIIQGQLPCARIYEDDRVLSFLDINPVARGHALVVPKRHYSTLFHIPPEDLEACIV 63

Query: 418 RMMSISRELLSKNNLSIEDARFGYHWPPFRSVKHLHLHTIAPESEMGF 561
               +   +      S  +     +    + + H HLH I   +  GF
Sbjct: 64  AAKRVGAAVFKGVGASGLNVLQNNYRAAGQLIDHFHLHLIPRHAHDGF 111


>UniRef50_Q83MZ3 Cluster: HIT-like protein; n=2; Tropheryma
           whipplei|Rep: HIT-like protein - Tropheryma whipplei
           (strain Twist) (Whipple's bacillus)
          Length = 107

 Score = 49.2 bits (112), Expect = 9e-05
 Identities = 32/102 (31%), Positives = 51/102 (50%)
 Frame = +1

Query: 244 IFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRM 423
           IF  I N+    EIL+EDDE     DI P ++ H L I K   +DV      D   +N++
Sbjct: 4   IFTRIINREVPAEILFEDDEFICIEDIAPKAKIHYLVIAKHPWKDVTEAVRDDPLFVNKI 63

Query: 424 MSISRELLSKNNLSIEDARFGYHWPPFRSVKHLHLHTIAPES 549
           ++I+   L+K+  S     F       ++V H+H H ++ E+
Sbjct: 64  LAIAVR-LTKDFGSQFRLIFNTGALVGQTVFHVHAHILSGEA 104


>UniRef50_Q6L1V3 Cluster: Asymmetrical
           bis(5'-nucleosyl)-tetraphosphatase; n=2;
           Thermoplasmatales|Rep: Asymmetrical
           bis(5'-nucleosyl)-tetraphosphatase - Picrophilus
           torridus
          Length = 141

 Score = 49.2 bits (112), Expect = 9e-05
 Identities = 20/50 (40%), Positives = 27/50 (54%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSL 390
           C+FC    K      +YEDD+V  F D  P    HIL IP+ H +D+ S+
Sbjct: 6   CVFCREIIKKRNAAFVYEDDDVVAFMDNAPIDNGHILVIPREHYQDIFSI 55


>UniRef50_O07513 Cluster: Protein hit; n=16; Bacillaceae|Rep:
           Protein hit - Bacillus subtilis
          Length = 145

 Score = 49.2 bits (112), Expect = 9e-05
 Identities = 36/107 (33%), Positives = 52/107 (48%), Gaps = 8/107 (7%)
 Frame = +1

Query: 241 CIFCNI-ANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLT-SADKELL 414
           CIFC I A  +   ++ YED+ V  F DI   ++ H L IPK HIE+V   T    K+  
Sbjct: 7   CIFCKIIAGDIPSAKV-YEDEHVLAFLDISQVTKGHTLVIPKTHIENVYEFTDELAKQYF 65

Query: 415 NRMMSISR------ELLSKNNLSIEDARFGYHWPPFRSVKHLHLHTI 537
           + +  I+R      E +  N L+    + G      +SV H H+H I
Sbjct: 66  HAVPKIARAIRDEFEPIGLNTLNNNGEKAG------QSVFHYHMHII 106


>UniRef50_Q7R1Q2 Cluster: GLP_28_16821_16420; n=1; Giardia lamblia
           ATCC 50803|Rep: GLP_28_16821_16420 - Giardia lamblia
           ATCC 50803
          Length = 133

 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 30/100 (30%), Positives = 45/100 (45%), Gaps = 1/100 (1%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLN- 417
           CIFC+I  +   +E +YED+ V  F DI P++  H + IPK H      L  A    L  
Sbjct: 2   CIFCSIVARDVPSEAVYEDEHVLAFLDIMPSAPGHCVVIPKYHAALFHELPPASAAALGA 61

Query: 418 RMMSISRELLSKNNLSIEDARFGYHWPPFRSVKHLHLHTI 537
            ++ +S  L+     S  +          + V H+H H I
Sbjct: 62  ALVKVSGALIKAMECSCYNIVNNNGPEAGQEVPHVHFHII 101


>UniRef50_Q7NAX8 Cluster: Hit-like; n=1; Mycoplasma
           gallisepticum|Rep: Hit-like - Mycoplasma gallisepticum
          Length = 146

 Score = 48.4 bits (110), Expect = 2e-04
 Identities = 26/101 (25%), Positives = 45/101 (44%), Gaps = 2/101 (1%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           C+FC I N      ++ ++D    F D  P S  H L IPK+H +D       +   +  
Sbjct: 16  CVFCKIINNEIQAHVVAQNDLAIAFLDAFPVSNGHTLVIPKKHHQDFSRTPKEEMHAVTD 75

Query: 421 MMSISRELLSKNNLSIEDARFGYHWPPF--RSVKHLHLHTI 537
           +     +LL +++L++    +  +      + V H HLH I
Sbjct: 76  LAQEVVKLLDRSDLNVHGYNYLSNQASIAGQEVFHFHLHII 116


>UniRef50_Q4P3W7 Cluster: Putative uncharacterized protein; n=1;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 240

 Score = 48.4 bits (110), Expect = 2e-04
 Identities = 23/76 (30%), Positives = 33/76 (43%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           C FC I        I+YED+    F DI P  R H L +PK+H+E V  L       L+ 
Sbjct: 54  CAFCRIIAGQSAAYIVYEDEHNLAFLDILPLRRGHTLVVPKKHVEQVSHLDQQTAAWLSN 113

Query: 421 MMSISRELLSKNNLSI 468
            +  +   + K    +
Sbjct: 114 ALVQTTRAVGKGEFHV 129


>UniRef50_P73481 Cluster: Uncharacterized HIT-like protein slr1234;
           n=8; cellular organisms|Rep: Uncharacterized HIT-like
           protein slr1234 - Synechocystis sp. (strain PCC 6803)
          Length = 114

 Score = 48.4 bits (110), Expect = 2e-04
 Identities = 27/99 (27%), Positives = 49/99 (49%), Gaps = 1/99 (1%)
 Frame = +1

Query: 244 IFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRM 423
           IF  I  +     I+YEDD    F+D+ P +  H+L IPK+ +  + + T  D  LL  +
Sbjct: 6   IFSKIIRREIPAAIVYEDDLCLAFKDVNPQAPVHVLLIPKKPLPQLSAATPEDHALLGHL 65

Query: 424 MSISRELLSKNNLSIEDARFGYHWPPF-RSVKHLHLHTI 537
           +  ++E+ +   +  +      +     ++V HLHLH +
Sbjct: 66  LLKAKEVAADLGIGDQFRLVINNGAEVGQTVFHLHLHIL 104


>UniRef50_Q9K9A6 Cluster: Cell-cycle regulation histidine triad;
           n=2; Bacillus|Rep: Cell-cycle regulation histidine triad
           - Bacillus halodurans
          Length = 169

 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 29/109 (26%), Positives = 46/109 (42%), Gaps = 2/109 (1%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           C  C +ANK     ++YED  VC   D  P    H L  PK H+ +++ +       + +
Sbjct: 28  CTGCMLANKQRPVHVVYEDQLVCGILDHDPFHEGHTLLFPKAHVIEIEDVNQKTANAIMK 87

Query: 421 MMSISRELLSK--NNLSIEDARFGYHWPPFRSVKHLHLHTIAPESEMGF 561
            ++I  + +    N   I   + G     F  + H H+H I  E E  F
Sbjct: 88  GVTIVVKAIKALYNPAGITICQNG---GEFNDLDHYHIHVIPREREPSF 133


>UniRef50_Q88X03 Cluster: Cell-cycle regulation histidine triad
           protein; n=26; Bacilli|Rep: Cell-cycle regulation
           histidine triad protein - Lactobacillus plantarum
          Length = 150

 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 38/130 (29%), Positives = 60/130 (46%), Gaps = 5/130 (3%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLN- 417
           CIFC I      +  +YEDD V  F DI   +  H L +PK H+ D+      D++L + 
Sbjct: 12  CIFCKIIKGDIPSYTVYEDDMVKAFLDISQGTPGHTLVVPKTHVADI---FGYDRDLASI 68

Query: 418 ---RMMSISREL-LSKNNLSIEDARFGYHWPPFRSVKHLHLHTIAPESEMGFIGRVIFKK 585
              R+  I+R +  +  N+   +         ++SV H H H I   S+     R+IFK 
Sbjct: 69  VFARIPEIARAIKATDENIIGMNIVNNNGAVAYQSVFHSHFHLIPRYSDKDDF-RMIFKD 127

Query: 586 NSYWFVSPEY 615
           N+  +   +Y
Sbjct: 128 NAKKYDETDY 137


>UniRef50_A3EUM2 Cluster: Histidine triad protein; n=1;
           Leptospirillum sp. Group II UBA|Rep: Histidine triad
           protein - Leptospirillum sp. Group II UBA
          Length = 118

 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 32/104 (30%), Positives = 55/104 (52%), Gaps = 5/104 (4%)
 Frame = +1

Query: 241 CIFCNIAN-KLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSAD-KELL 414
           CIFC I N ++   +IL E D V +  D+ P + FH L + +RH+ D+ +L   D  EL+
Sbjct: 6   CIFCRILNGEIPSKKILEEADGVAIL-DVNPQAPFHALVLSRRHVGDMATLLKVDGGELV 64

Query: 415 -NRMMSISRELLSKNNLSIEDARFGYHW--PPFRSVKHLHLHTI 537
             ++M ++  +     LS +  R   +      ++V HLH+H +
Sbjct: 65  AGKLMRMAVNVARDAGLSPDGYRVVINTGNNGGQTVAHLHVHVL 108


>UniRef50_UPI000050FB45 Cluster: COG0537: Diadenosine tetraphosphate
           (Ap4A) hydrolase and other HIT family hydrolases; n=1;
           Brevibacterium linens BL2|Rep: COG0537: Diadenosine
           tetraphosphate (Ap4A) hydrolase and other HIT family
           hydrolases - Brevibacterium linens BL2
          Length = 144

 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 22/55 (40%), Positives = 33/55 (60%), Gaps = 1/55 (1%)
 Frame = +1

Query: 241 CIFCNI-ANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSAD 402
           C+FC I A  + G ++  E +    F DI+P S  H+L +PKRH  D++ + SAD
Sbjct: 5   CLFCGIVAGDVPGAKVA-ETETTYAFMDIQPGSDGHLLVVPKRHSTDLRDIPSAD 58


>UniRef50_Q3W573 Cluster: Histidine triad (HIT) protein; n=3;
           Actinomycetales|Rep: Histidine triad (HIT) protein -
           Frankia sp. EAN1pec
          Length = 148

 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 28/102 (27%), Positives = 49/102 (48%), Gaps = 5/102 (4%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           C+FC I ++     I++EDD    F D +P +  H+L IPK H   ++ L   D+ +  +
Sbjct: 10  CVFCAIVHRGTAASIIHEDDTALAFMDHRPVTPGHLLVIPKAHAVGLEDL---DERVGTQ 66

Query: 421 MMSISREL---LSKNNLSIEDAR--FGYHWPPFRSVKHLHLH 531
           +  ++  L   L ++ L  E            F+ + H+HLH
Sbjct: 67  VWLVAHRLGRALRRSGLRCEGVNLFLADGEAAFQEIFHVHLH 108


>UniRef50_Q02WI9 Cluster: Diadenosine tetraphosphate (Ap4A)
           hydrolase related HIT family hydrolase; n=5;
           Firmicutes|Rep: Diadenosine tetraphosphate (Ap4A)
           hydrolase related HIT family hydrolase - Lactococcus
           lactis subsp. cremoris (strain SK11)
          Length = 122

 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 27/100 (27%), Positives = 48/100 (48%), Gaps = 1/100 (1%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           C FC + +K+      +E++    F D  P S  HIL  PKRH+     LT  ++E +  
Sbjct: 4   CPFCEVKDKV------FENELAQAFYDAYPVSEGHILITPKRHVASYFELTKYEREAIEE 57

Query: 421 MMSISRELLSKN-NLSIEDARFGYHWPPFRSVKHLHLHTI 537
           ++ +S+  L +N + +  +          ++V H H+H I
Sbjct: 58  LLELSKSHLDENFHANAYNIGINVGHAAGQTVFHCHVHLI 97


>UniRef50_A0LCF6 Cluster: Histidine triad (HIT) protein; n=3;
           Bacteria|Rep: Histidine triad (HIT) protein -
           Magnetococcus sp. (strain MC-1)
          Length = 117

 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 26/101 (25%), Positives = 47/101 (46%), Gaps = 2/101 (1%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           C+FC I         +YED+ V  FRDI P +  H+L IPK+HI  +  +    + ++  
Sbjct: 5   CLFCKIVAGTIPCNKVYEDELVLAFRDIHPQAPEHVLVIPKQHIATLDDVQVQARAVMGH 64

Query: 421 MMSISRELLSKNNLSIEDAR--FGYHWPPFRSVKHLHLHTI 537
           +M  +  +     ++ +  R          + V H+H+H +
Sbjct: 65  LMERTAHVARLIGVAEKGYRTLINTRGDGGQEVYHIHVHIL 105


>UniRef50_UPI00015C430C Cluster: HIT family protein; n=1;
           Streptococcus gordonii str. Challis substr. CH1|Rep: HIT
           family protein - Streptococcus gordonii str. Challis
           substr. CH1
          Length = 173

 Score = 47.2 bits (107), Expect = 4e-04
 Identities = 27/101 (26%), Positives = 51/101 (50%), Gaps = 2/101 (1%)
 Frame = +1

Query: 241 CIFCNI-ANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLT-SADKELL 414
           CIFC I A  +   ++ YED+ V  F DI   +  H L +PK+H  ++  +  S+  +L 
Sbjct: 39  CIFCKIIAGDIPAAKV-YEDEAVLAFLDISQVTPGHTLVVPKQHFRNLLDMDGSSSSQLF 97

Query: 415 NRMMSISRELLSKNNLSIEDARFGYHWPPFRSVKHLHLHTI 537
            R+  I+R+++   + +  +          ++V H H+H +
Sbjct: 98  ERVPQIARKVMKVTDAAGMNIINNNEEIAGQTVFHTHVHLV 138


>UniRef50_Q98RK0 Cluster: HIT-LIKE PROTEIN; n=2; Mycoplasma|Rep:
           HIT-LIKE PROTEIN - Mycoplasma pulmonis
          Length = 116

 Score = 47.2 bits (107), Expect = 4e-04
 Identities = 30/102 (29%), Positives = 51/102 (50%), Gaps = 4/102 (3%)
 Frame = +1

Query: 244 IFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRM 423
           IF  I ++ E  +I+YEDD+     D  P +  H L IPK+H  ++K +   +++ +N +
Sbjct: 8   IFKKIIDRKEPAQIIYEDDQAIAIMDKFPYNPGHFLVIPKKHSTNLKDI---EEQSINHL 64

Query: 424 MSISRELLSK--NNLSIEDAR--FGYHWPPFRSVKHLHLHTI 537
           M I+ +L  +   N   ED +          + V H H+H I
Sbjct: 65  MKIAIKLAKEKIENKEFEDFKLIINNGEKAGQVVYHTHIHII 106


>UniRef50_Q727L0 Cluster: HIT family protein; n=2;
           Deltaproteobacteria|Rep: HIT family protein -
           Desulfovibrio vulgaris (strain Hildenborough / ATCC
           29579 / NCIMB8303)
          Length = 142

 Score = 47.2 bits (107), Expect = 4e-04
 Identities = 30/101 (29%), Positives = 49/101 (48%), Gaps = 2/101 (1%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           CIFC + +      ++ E+      RD    +  H+L IPKRH ED  SLT A+K   + 
Sbjct: 10  CIFCALQHS---PHMVRENATCYAIRDKYAVTEGHLLIIPKRHTEDYFSLTQAEKRDADA 66

Query: 421 MMSISRELLSKNNLSIEDARFGYHW--PPFRSVKHLHLHTI 537
           ++   R+ L+  + SI     G +      +++ H H+H I
Sbjct: 67  LLRELRDELASADASISGFNVGVNCGEDAGQTIFHAHIHLI 107


>UniRef50_Q2BQP2 Cluster: HIT domain protein; n=1; Neptuniibacter
           caesariensis|Rep: HIT domain protein - Neptuniibacter
           caesariensis
          Length = 84

 Score = 47.2 bits (107), Expect = 4e-04
 Identities = 23/67 (34%), Positives = 37/67 (55%)
 Frame = +1

Query: 244 IFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRM 423
           +FC IA   E  E +Y+D+    F+D  P +  H+L IP +HI ++  L  A   L+  +
Sbjct: 1   MFCCIARGEEAAECVYQDEYRVAFKDRAPKAPVHLLVIPCQHIRNLNDLREAGAALVAHL 60

Query: 424 MSISREL 444
           +  SR+L
Sbjct: 61  VLKSRKL 67


>UniRef50_Q1FG87 Cluster: Histidine triad (HIT) protein; n=5;
           Clostridiales|Rep: Histidine triad (HIT) protein -
           Clostridium phytofermentans ISDg
          Length = 138

 Score = 47.2 bits (107), Expect = 4e-04
 Identities = 23/68 (33%), Positives = 40/68 (58%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           CIFC +A+    +  +YEDD      DI PAS+ H L +PK+H  ++  L   +   ++R
Sbjct: 6   CIFCKLASGEFQSATVYEDDLFRAILDISPASKGHTLLLPKKHAANLFELEEPE---VSR 62

Query: 421 MMSISREL 444
            +S++++L
Sbjct: 63  ALSVAKKL 70


>UniRef50_A6PM84 Cluster: Histidine triad (HIT) protein; n=1;
           Victivallis vadensis ATCC BAA-548|Rep: Histidine triad
           (HIT) protein - Victivallis vadensis ATCC BAA-548
          Length = 142

 Score = 47.2 bits (107), Expect = 4e-04
 Identities = 35/111 (31%), Positives = 45/111 (40%), Gaps = 4/111 (3%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           CIFC IA        +YED+ V  F DI P +  H L IPK H E   ++  A      R
Sbjct: 4   CIFCKIAAGEIPAVKIYEDELVLAFLDIGPINFGHTLVIPKEHHESSSTIPEA---TAGR 60

Query: 421 MMSISRELLSKNNLSIEDARFGYHWPPFRS----VKHLHLHTIAPESEMGF 561
           M  I   +       ++   F  H     +    V H HLH +    E GF
Sbjct: 61  MFHIGSRIGIALRRELDYDAFNLHLADGTAAGQVVPHAHLHVVPRGVEDGF 111


>UniRef50_A5Z767 Cluster: Putative uncharacterized protein; n=1;
           Eubacterium ventriosum ATCC 27560|Rep: Putative
           uncharacterized protein - Eubacterium ventriosum ATCC
           27560
          Length = 136

 Score = 47.2 bits (107), Expect = 4e-04
 Identities = 35/103 (33%), Positives = 50/103 (48%), Gaps = 4/103 (3%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           CIFC IA     +  L+EDD+V V  D  PA+  H L IPK H  +V  +   D ELL  
Sbjct: 4   CIFCKIAGGEIPSITLFEDDKVKVIFDAGPATVGHALVIPKSHAANVFEI---DDELLAH 60

Query: 421 MMSISRELLS--KNNLSIEDARFGYHWPPF--RSVKHLHLHTI 537
              +++++ +  K     E      +      +SV HLH+H I
Sbjct: 61  AHIVAKKVATALKEATGCEGVNILQNNGEIAGQSVFHLHIHVI 103


>UniRef50_Q4N9V7 Cluster: Protein kinase C interacting protein 1,
           putative; n=2; Theileria|Rep: Protein kinase C
           interacting protein 1, putative - Theileria parva
          Length = 180

 Score = 47.2 bits (107), Expect = 4e-04
 Identities = 30/89 (33%), Positives = 48/89 (53%), Gaps = 4/89 (4%)
 Frame = +1

Query: 286 LYEDDEVCVFRDIKPASRFHILTIPKR--HIEDVKSLTSADKELLNRMMSISRELLSKNN 459
           +YEDD V  F DI+PAS  HIL IPK    +  +   T   +++L  M+  +  +  +NN
Sbjct: 85  VYEDDLVLAFYDIQPASPSHILIIPKEMDGLASLSDATERHEKVLGHMLVKAAHIAKENN 144

Query: 460 LSIEDARFGYHWPP--FRSVKHLHLHTIA 540
           L   D R   +  P   ++V +LH+H ++
Sbjct: 145 LG--DFRVVINSGPGALQTVFYLHMHLMS 171


>UniRef50_Q16F08 Cluster: Putative uncharacterized protein; n=2;
           Aedes aegypti|Rep: Putative uncharacterized protein -
           Aedes aegypti (Yellowfever mosquito)
          Length = 188

 Score = 47.2 bits (107), Expect = 4e-04
 Identities = 24/79 (30%), Positives = 40/79 (50%)
 Frame = +1

Query: 310 VFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLSIEDARFGY 489
           V RD  P +R H L +P  +I++V  L      LL  M  ++++ +  N    ++   G+
Sbjct: 30  VIRDKYPKARHHFLVLPWANIDNVYELIPVHIPLLKEMFQLAKQAIELNRCHQKEFAMGF 89

Query: 490 HWPPFRSVKHLHLHTIAPE 546
           H  P  S+  LHLH I+ +
Sbjct: 90  HMRP--SMHRLHLHVISKD 106


>UniRef50_Q8K9I9 Cluster: Uncharacterized HIT-like protein BUsg_345;
           n=4; Enterobacteriaceae|Rep: Uncharacterized HIT-like
           protein BUsg_345 - Buchnera aphidicola subsp. Schizaphis
           graminum
          Length = 115

 Score = 47.2 bits (107), Expect = 4e-04
 Identities = 25/103 (24%), Positives = 48/103 (46%), Gaps = 2/103 (1%)
 Frame = +1

Query: 244 IFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRM 423
           IF  I  +   T I+Y+D  V  F DI P +  HI+ IP   I+ +  +   +K +   M
Sbjct: 7   IFQKIIKRETSTHIIYQDKIVTAFEDIAPKAPIHIIVIPNIFIKTLNDINQKNKNIFAHM 66

Query: 424 MSISRELLSKNNLSIEDAR--FGYHWPPFRSVKHLHLHTIAPE 546
           + I+ ++     +S +  +     +    + + +LH+H +  E
Sbjct: 67  LYIAVKIAKNKKISEDGYKIVMNCNKNGGQEINYLHMHLLGGE 109


>UniRef50_Q8EW55 Cluster: Histidine triad protein HIT; n=1;
           Mycoplasma penetrans|Rep: Histidine triad protein HIT -
           Mycoplasma penetrans
          Length = 145

 Score = 46.8 bits (106), Expect = 5e-04
 Identities = 25/68 (36%), Positives = 37/68 (54%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           C+FC I NK   + I+ E+     F DI PAS  H L IPK+H  D   L   D+  L  
Sbjct: 9   CLFCKIVNKEIPSNIVDENAYALAFLDISPASDGHTLVIPKKHCID---LVHCDELYLKE 65

Query: 421 MMSISREL 444
            +S+++++
Sbjct: 66  TISLAKKV 73


>UniRef50_Q8DK69 Cluster: Histidine triad nucleotide-binding
           protein; n=15; Bacteria|Rep: Histidine triad
           nucleotide-binding protein - Synechococcus elongatus
           (Thermosynechococcus elongatus)
          Length = 114

 Score = 46.8 bits (106), Expect = 5e-04
 Identities = 29/100 (29%), Positives = 48/100 (48%), Gaps = 2/100 (2%)
 Frame = +1

Query: 244 IFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRM 423
           IF  I  +    +I++ED+    FRDI P +  HIL IPK+ I  +      D  +L  +
Sbjct: 6   IFSRIIRREIPADIVHEDELCLAFRDINPQAPVHILVIPKKPIPQLSLAEPEDHRVLGHL 65

Query: 424 MSISRELLSKNNLSIEDARFGYHWPP--FRSVKHLHLHTI 537
           +  ++ +     L+    R   +  P   ++V HLHLH +
Sbjct: 66  LLTAKRIAEAEGLT-NGYRVVINNGPDGGQTVYHLHLHLL 104


>UniRef50_A7D556 Cluster: Histidine triad (HIT) protein; n=1;
           Halorubrum lacusprofundi ATCC 49239|Rep: Histidine triad
           (HIT) protein - Halorubrum lacusprofundi ATCC 49239
          Length = 152

 Score = 46.8 bits (106), Expect = 5e-04
 Identities = 31/103 (30%), Positives = 49/103 (47%), Gaps = 4/103 (3%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           CIFC+I +       ++E D+V  F D  P +  H L IPK H + V  L   D +L + 
Sbjct: 14  CIFCSIVDGDIPARTVHETDDVLAFLDANPLAPGHTLVIPKAHAQHVGDL---DDDLASD 70

Query: 421 MMSISRELLSKNNLSI--EDARFGYH--WPPFRSVKHLHLHTI 537
           + +   EL  +   ++  E A  G +      + V H+H+H I
Sbjct: 71  LFAAVTELTPRVQAAVDAEGANVGINDGEAAGQEVPHVHVHVI 113


>UniRef50_UPI00003C03A1 Cluster: PREDICTED: similar to aprataxin;
           n=1; Apis mellifera|Rep: PREDICTED: similar to aprataxin
           - Apis mellifera
          Length = 194

 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 29/85 (34%), Positives = 47/85 (55%)
 Frame = +1

Query: 292 EDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLSIE 471
           EDD++ V +D  P ++ H L IPK  I  +  +   +++LL  M +I+ + L+K +   E
Sbjct: 37  EDDKIIVIKDKYPKAQNHYLIIPKIDIPSLWHVKKENEDLLLHMHAIAED-LTKEHKEFE 95

Query: 472 DARFGYHWPPFRSVKHLHLHTIAPE 546
               GYH  P  S+  LHLH I+ +
Sbjct: 96  -FLIGYHAVP--SMHRLHLHVISTD 117


>UniRef50_Q6A7Y9 Cluster: Putative cell-cycle regulation histidine
           triad protein; n=1; Propionibacterium acnes|Rep:
           Putative cell-cycle regulation histidine triad protein -
           Propionibacterium acnes
          Length = 136

 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 29/99 (29%), Positives = 43/99 (43%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           C+FC+IA       I+  DD    F DI+P    H L IP+RH+  V         +   
Sbjct: 3   CLFCSIAAGDIPATIIDSDDASVAFLDIEPFQDGHTLVIPRRHVTSVLDDDGELGRISPM 62

Query: 421 MMSISRELLSKNNLSIEDARFGYHWPPFRSVKHLHLHTI 537
           +  ++R L+     S  +          +SV HLH+H I
Sbjct: 63  VTKVARRLVDSLGASGVNVVSNAGEVAGQSVHHLHVHVI 101


>UniRef50_Q4FMD8 Cluster: Diadenosine tetraphosphate (Ap4A)
           hydrolase and other HIT family hydrolases; n=3;
           Bacteria|Rep: Diadenosine tetraphosphate (Ap4A)
           hydrolase and other HIT family hydrolases - Pelagibacter
           ubique
          Length = 144

 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 35/125 (28%), Positives = 56/125 (44%), Gaps = 7/125 (5%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           C+FCN  +K  G  +  E+D      D  P S FH L IPKRH+ D   L   +    N 
Sbjct: 20  CLFCN--SKQSG--LAAENDLAYASYDTYPVSEFHCLIIPKRHVVDYFDLNDDEVIACNN 75

Query: 421 MMSISRELLSKNNLSIEDARFGYHWPPF--RSVKHLHLHTIA-----PESEMGFIGRVIF 579
           ++   +E +   + +++    G +      +S+ H H+H I       ++  G +  VI 
Sbjct: 76  LIKQIKEEILLKDPAVKGFNIGTNAGVIAGQSILHCHIHLIPRREGDVDNPQGGVRSVIP 135

Query: 580 KKNSY 594
           KK  Y
Sbjct: 136 KKQHY 140


>UniRef50_Q93IL6 Cluster: Histidine nucleotide-binding protein; n=3;
           Thermus thermophilus|Rep: Histidine nucleotide-binding
           protein - Thermus thermophilus
          Length = 107

 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 19/56 (33%), Positives = 32/56 (57%), Gaps = 1/56 (1%)
 Frame = +1

Query: 241 CIFCNI-ANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADK 405
           C+FC I A +L   ++ YED+    F DI+P +  H+L +PK H+E +      ++
Sbjct: 3   CVFCRIIAGELPSKKV-YEDEGFVAFHDIRPKAPVHVLVVPKEHVEKLSDYPDTEE 57


>UniRef50_Q2BE03 Cluster: Cell-cycle regulation histidine triad, Hit
           family protein; n=1; Bacillus sp. NRRL B-14911|Rep:
           Cell-cycle regulation histidine triad, Hit family
           protein - Bacillus sp. NRRL B-14911
          Length = 146

 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 28/111 (25%), Positives = 50/111 (45%), Gaps = 4/111 (3%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           C+ C +A+K E   I+YE++ +    D  P    H+L +PK+H E++  L       + R
Sbjct: 4   CLGCRLAHKSEPVFIIYENNLISCILDHDPFGEGHVLILPKKHAEELTDLDEESAVAVFR 63

Query: 421 ----MMSISRELLSKNNLSIEDARFGYHWPPFRSVKHLHLHTIAPESEMGF 561
               + ++ + L   + +++   R G     F  + H HLH I       F
Sbjct: 64  AAQHLSTVIKRLYKPDGITLCQKR-GI----FNDLNHFHLHVIPRRQRQPF 109


>UniRef50_Q5KLA4 Cluster: Hydrolase, putative; n=2; Dikarya|Rep:
           Hydrolase, putative - Cryptococcus neoformans
           (Filobasidiella neoformans)
          Length = 140

 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 29/106 (27%), Positives = 45/106 (42%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           CIFC I      +  L E + V  F D+ P +R H L IPK+H     + T    E +  
Sbjct: 7   CIFCKIIKGEIPSMKLLETESVFAFMDVGPIARGHCLVIPKQH---AATFTELPDEAMVD 63

Query: 421 MMSISRELLSKNNLSIEDARFGYHWPPFRSVKHLHLHTIAPESEMG 558
           ++   ++L +       +       P  + V H+H H I   +E G
Sbjct: 64  ILPTCKKLAAATGAENYNILQNNGRPAHQVVDHVHFHVIPKPAEAG 109


>UniRef50_A7BYS1 Cluster: HIT family protein; n=2;
           Proteobacteria|Rep: HIT family protein - Beggiatoa sp.
           PS
          Length = 125

 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 31/100 (31%), Positives = 48/100 (48%), Gaps = 1/100 (1%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSAD-KELLN 417
           C FC++ +K    +I+++D+ V   RD  P S  H L IPKRHI  +   T+ + + LLN
Sbjct: 5   CPFCHLDDK----QIIFQDEFVFTIRDGFPISSAHTLIIPKRHIASLFDATNKEQRALLN 60

Query: 418 RMMSISRELLSKNNLSIEDARFGYHWPPFRSVKHLHLHTI 537
            +     EL         +          ++V HLH+H I
Sbjct: 61  ALQFTKTELDQIYKPDGYNIGLNDGLAAGQTVMHLHIHLI 100


>UniRef50_Q9V017 Cluster: Histidine triad (HIT) protein; n=4;
           Thermococcaceae|Rep: Histidine triad (HIT) protein -
           Pyrococcus abyssi
          Length = 147

 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 30/101 (29%), Positives = 53/101 (52%), Gaps = 2/101 (1%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           C FC+   K E   ++YED  + +  D  PA+  H+L +PKRH+  + +LT  +K  L +
Sbjct: 3   CPFCH--PKPEN--VVYEDKFIRILLDNYPANPGHLLVVPKRHVTSIGNLTEDEKLALLK 58

Query: 421 MMSISRELLSKNNLSIEDARFGYH--WPPFRSVKHLHLHTI 537
            + ++ + L K  L  +    G +      ++V H+H+H I
Sbjct: 59  GIELAVKAL-KRALKADGFNVGINIGKAAGQTVDHIHIHVI 98


>UniRef50_Q5UZ82 Cluster: Histidine triad protein; n=4;
           Halobacteriaceae|Rep: Histidine triad protein -
           Haloarcula marismortui (Halobacterium marismortui)
          Length = 142

 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 36/104 (34%), Positives = 48/104 (46%), Gaps = 5/104 (4%)
 Frame = +1

Query: 241 CIFCNI-ANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLN 417
           CIFC I A  + G  + YEDD V  F D  P S  H L IPK H E +   T AD  + +
Sbjct: 5   CIFCQIVAGDIPGRTV-YEDDTVLAFLDANPLSPGHTLVIPKAHHERLND-TPAD--VAS 60

Query: 418 RMMSISRELLSKNNLSIE----DARFGYHWPPFRSVKHLHLHTI 537
            +MS   EL+     +++       F       + V H+H H I
Sbjct: 61  AVMSTLHELVPAVESAVDAPASTVAFNNGEVAGQEVPHVHGHII 104


>UniRef50_Q74I95 Cluster: Hit protein; n=5; Lactobacillus|Rep: Hit
           protein - Lactobacillus johnsonii
          Length = 144

 Score = 45.6 bits (103), Expect = 0.001
 Identities = 26/106 (24%), Positives = 50/106 (47%), Gaps = 2/106 (1%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           C+FC I      +  ++E+D+V  F DI   ++ H L IPK+H+ +    +  D     +
Sbjct: 8   CLFCKIIRGEIPSYTVFENDDVKAFLDISQVTKGHTLIIPKKHLVNFFDYSQEDAARFLQ 67

Query: 421 MMSISRELLSKNNLSIEDARFGYHWPPF--RSVKHLHLHTIAPESE 552
            + +  + + K++ +I+      +      + V H H+H I   SE
Sbjct: 68  YIPVIAQAIKKSDPTIKGLNVEVNNGEIAGQVVMHSHIHLIPRRSE 113


>UniRef50_A4J7H7 Cluster: Histidine triad (HIT) protein; n=4;
           cellular organisms|Rep: Histidine triad (HIT) protein -
           Desulfotomaculum reducens MI-1
          Length = 169

 Score = 45.6 bits (103), Expect = 0.001
 Identities = 23/60 (38%), Positives = 34/60 (56%), Gaps = 2/60 (3%)
 Frame = +1

Query: 241 CIFCNIANKLEGTE--ILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELL 414
           CIFC   N  +  E  ++Y  D+  V  ++ P +  H+L  PKRH+ D+  LT  D+ELL
Sbjct: 20  CIFCEKLNSDQDEENLVIYRGDKTFVIMNLYPYNNGHLLIAPKRHVGDITELT--DEELL 77


>UniRef50_Q74ND2 Cluster: NEQ213; n=1; Nanoarchaeum equitans|Rep:
           NEQ213 - Nanoarchaeum equitans
          Length = 188

 Score = 45.6 bits (103), Expect = 0.001
 Identities = 23/65 (35%), Positives = 40/65 (61%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           C+FC IA+    +  +YED+++ V  DI PA    +L IPK+H+  +  L   D+E+L++
Sbjct: 3   CLFCAIASGQIPSYKIYEDNDLVVVLDIYPAHPGQLLIIPKQHVTFIWEL---DREILHK 59

Query: 421 MMSIS 435
           ++  S
Sbjct: 60  ILEAS 64


>UniRef50_Q7W2C9 Cluster: Histidine triad protein; n=4;
           Proteobacteria|Rep: Histidine triad protein - Bordetella
           parapertussis
          Length = 145

 Score = 45.2 bits (102), Expect = 0.001
 Identities = 26/123 (21%), Positives = 50/123 (40%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           C+FC I+ +     ++++D  +  F DI P    H+L IP++H    + + +   +L   
Sbjct: 5   CLFCRISREEIPAHVIHQDSRLLAFLDIHPVRPGHVLIIPRQHYPYFEDMPA---DLAGH 61

Query: 421 MMSISRELLSKNNLSIEDARFGYHWPPFRSVKHLHLHTIAPESEMGFIGRVIFKKNSYWF 600
           ++++ + L           R G+ +     V H H H I              ++    F
Sbjct: 62  ILNLGQRLARHMKRLYSVERVGFAFTGIH-VAHAHAHLIPMHHPQDVTSTQYIEQKDLTF 120

Query: 601 VSP 609
           V P
Sbjct: 121 VMP 123


>UniRef50_Q6AEC2 Cluster: Putative uncharacterized protein; n=3;
           Actinobacteria (class)|Rep: Putative uncharacterized
           protein - Leifsonia xyli subsp. xyli
          Length = 132

 Score = 45.2 bits (102), Expect = 0.001
 Identities = 23/88 (26%), Positives = 46/88 (52%), Gaps = 1/88 (1%)
 Frame = +1

Query: 280 EILYEDDEVCVFRDIKPASRFHILTIPKR-HIEDVKSLTSADKELLNRMMSISRELLSKN 456
           +++Y+ + +  F+DI P +  H+L +PK     DV  L + D ELL  +++ +R L +++
Sbjct: 31  DVVYDGERLIAFKDIAPQAPVHLLVVPKTDQYRDVVELAAGDPELLAELVATARSLAAEH 90

Query: 457 NLSIEDARFGYHWPPFRSVKHLHLHTIA 540
                   F       ++V H+H H ++
Sbjct: 91  ADGDFRLIFNTGANAGQTVFHVHAHVLS 118


>UniRef50_Q702F5 Cluster: Putative HIT superfamily hydrolase; n=1;
           uncultured crenarchaeote|Rep: Putative HIT superfamily
           hydrolase - uncultured crenarchaeote
          Length = 146

 Score = 45.2 bits (102), Expect = 0.001
 Identities = 28/108 (25%), Positives = 47/108 (43%), Gaps = 2/108 (1%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           CIFCNIA  +    I+ E++    F D  P  R H L   K H   ++ + S +   L  
Sbjct: 10  CIFCNIAKYITKARIISENEHAVAFLDAFPLRRGHTLVATKMHWVKLQEINSDEIVALFG 69

Query: 421 MMSISRELLSKNNLSIEDARFGYH--WPPFRSVKHLHLHTIAPESEMG 558
           ++S+  + L K  +         H      + + HLH+H +  + + G
Sbjct: 70  LVSLVADALEK-GMDANATLIAIHNGKQAGQEIPHLHVHILPRKRDDG 116


>UniRef50_P42856 Cluster: 14 kDa zinc-binding protein; n=11;
           Eukaryota|Rep: 14 kDa zinc-binding protein - Zea mays
           (Maize)
          Length = 128

 Score = 45.2 bits (102), Expect = 0.001
 Identities = 31/103 (30%), Positives = 55/103 (53%), Gaps = 5/103 (4%)
 Frame = +1

Query: 244 IFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADK---ELL 414
           IF  I  K   + ++YED++V  FRDI P +  HIL IPK   + +  L  A++   E+L
Sbjct: 18  IFDKIIKKEIPSTVVYEDEKVLAFRDINPQAPTHILIIPKVK-DGLTGLAKAEERHIEIL 76

Query: 415 NRMMSISRELLSKNNLSIEDARFGYHWPP--FRSVKHLHLHTI 537
             ++ +++ +  +  L  +  R   +  P   +SV H+H+H +
Sbjct: 77  GYLLYVAKVVAKQEGLE-DGYRVVINDGPSGCQSVYHIHVHLL 118


>UniRef50_A0RUN5 Cluster: Diadenosine tetraphosphate hydrolase; n=4;
           Crenarchaeota|Rep: Diadenosine tetraphosphate hydrolase
           - Cenarchaeum symbiosum
          Length = 138

 Score = 44.8 bits (101), Expect = 0.002
 Identities = 30/108 (27%), Positives = 51/108 (47%), Gaps = 4/108 (3%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADK----E 408
           C+FC IA+      I+ E      F D  P +R H L IPK H E ++ +  ++     E
Sbjct: 6   CVFCKIASGELPARIISETGNTIAFMDAFPVARGHSLVIPKGHYERMQEIPESENADLFE 65

Query: 409 LLNRMMSISRELLSKNNLSIEDARFGYHWPPFRSVKHLHLHTIAPESE 552
           ++ R+++   E+     +++ + R        + V H H+H I P SE
Sbjct: 66  VVRRVVARVDEMGGSTLVALHNGR-----GSGQEVPHAHVHLI-PRSE 107


>UniRef50_Q9ZDL1 Cluster: Uncharacterized HIT-like protein RP317;
           n=13; Rickettsiales|Rep: Uncharacterized HIT-like
           protein RP317 - Rickettsia prowazekii
          Length = 120

 Score = 44.8 bits (101), Expect = 0.002
 Identities = 28/110 (25%), Positives = 50/110 (45%), Gaps = 3/110 (2%)
 Frame = +1

Query: 244 IFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPK-RHIEDVKSLTSADKELLNR 420
           +F  I  K    EI+YED ++  F+DI P +  HI+ IPK  +I+    ++ A  + +  
Sbjct: 7   VFAKIITKNLPAEIIYEDKQILAFKDIAPIAPVHIIVIPKNEYIDYTDFISKASIDEIKH 66

Query: 421 MMSISRELLSKNNLSIEDARF--GYHWPPFRSVKHLHLHTIAPESEMGFI 564
             S   ++ ++  L     R          +++ H H H I  +  +G I
Sbjct: 67  FFSKIADIANEAGLDKVGYRLITNKGEKSGQTIFHFHFHIIGGKKLIGLI 116


>UniRef50_Q6I3E1 Cluster: HIT family protein; n=9; Bacillus cereus
           group|Rep: HIT family protein - Bacillus anthracis
          Length = 145

 Score = 44.4 bits (100), Expect = 0.003
 Identities = 28/108 (25%), Positives = 47/108 (43%), Gaps = 1/108 (0%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTS-ADKELLN 417
           C+ C +A   E    +YEDD V  F D +P    H L +PK+H+ +V  L     K +++
Sbjct: 4   CLGCRLAGGEEKIYKVYEDDYVTCFLDHEPFYTGHTLIVPKQHVVEVDELDDVVAKSIMD 63

Query: 418 RMMSISRELLSKNNLSIEDARFGYHWPPFRSVKHLHLHTIAPESEMGF 561
               I++ +  K     +      +   F  + H H+H +    E  F
Sbjct: 64  ASKLITKAI--KLLYKPDGVTVCQNGGIFNELTHYHMHVVPRYKERSF 109


>UniRef50_A7H3E9 Cluster: HIT family protein; n=11;
           Campylobacter|Rep: HIT family protein - Campylobacter
           jejuni subsp. doylei 269.97
          Length = 121

 Score = 44.4 bits (100), Expect = 0.003
 Identities = 24/63 (38%), Positives = 35/63 (55%)
 Frame = +1

Query: 256 IANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSIS 435
           +  KL   ++L E D+   F DI P +  HIL IPK+H +D +     D EL+ +M S  
Sbjct: 11  VEGKLPCNKVL-ESDDFLAFHDIAPKAPIHILIIPKKHFKDFQEF---DPELMAKMTSFI 66

Query: 436 REL 444
           +EL
Sbjct: 67  QEL 69


>UniRef50_A6WDH4 Cluster: Histidine triad (HIT) protein; n=2;
           Actinomycetales|Rep: Histidine triad (HIT) protein -
           Kineococcus radiotolerans SRS30216
          Length = 121

 Score = 44.4 bits (100), Expect = 0.003
 Identities = 25/94 (26%), Positives = 46/94 (48%)
 Frame = +1

Query: 256 IANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSIS 435
           +A ++  T I++ DD V  F D+ P +  H+L IP+   E+V  L +A    L R++ ++
Sbjct: 19  VAGEVPAT-IVHSDDLVVAFEDVNPQAPVHVLVIPRERHENVAQLAAAAPATLARLVEVA 77

Query: 436 RELLSKNNLSIEDARFGYHWPPFRSVKHLHLHTI 537
           + +  +         F       +SV H+H H +
Sbjct: 78  QRIADERCGGEYRLVFNTGTAVGQSVFHVHGHVL 111


>UniRef50_A1AWF6 Cluster: Histidine triad (HIT) protein; n=1;
           Candidatus Ruthia magnifica str. Cm (Calyptogena
           magnifica)|Rep: Histidine triad (HIT) protein - Ruthia
           magnifica subsp. Calyptogena magnifica
          Length = 130

 Score = 44.4 bits (100), Expect = 0.003
 Identities = 32/126 (25%), Positives = 57/126 (45%), Gaps = 7/126 (5%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           C+FC ++ +     I+ + D    F D  P S  H L +PKRH+     +T  ++  + +
Sbjct: 5   CLFCQLSEE----RIIGQCDLTITFLDSYPVSPGHTLIVPKRHVATYFDITEQEQNAIAK 60

Query: 421 MMSISRELLSKNNLSIEDARFGYHWPPF--RSVKHLHLHTIA-----PESEMGFIGRVIF 579
            +  S+ +L +   S +    G +      +S+ HLH+H I       ++  G +  VI 
Sbjct: 61  AIQKSKLILDE-EFSPDGFNIGMNNGEVAGQSIMHLHVHMIPRYKNDVKNPKGGVRWVIS 119

Query: 580 KKNSYW 597
            K  YW
Sbjct: 120 NKADYW 125


>UniRef50_A1RXN8 Cluster: Histidine triad (HIT) protein; n=1;
           Thermofilum pendens Hrk 5|Rep: Histidine triad (HIT)
           protein - Thermofilum pendens (strain Hrk 5)
          Length = 167

 Score = 44.4 bits (100), Expect = 0.003
 Identities = 28/104 (26%), Positives = 50/104 (48%), Gaps = 5/104 (4%)
 Frame = +1

Query: 241 CIFCNI--ANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELL 414
           C  C    +++LE   ++Y+ +++ V  +  P +  H+L  P RH+ D   L+  +   L
Sbjct: 24  CFICKAVESSELEENLVVYKGEKIIVMLNRYPYNTGHLLVAPTRHVADFSQLSDEELFSL 83

Query: 415 NRMMSISRELLSKNNLSIEDARFGYHWPPFRSV---KHLHLHTI 537
            + +S+S ELL K  LS +    G +           HLH+H +
Sbjct: 84  AKAVSLSLELL-KKALSPDGFNVGVNLGRVAGAGLESHLHVHVV 126


>UniRef50_P49774 Cluster: Uncharacterized HIT-like protein ML2237;
           n=23; Actinomycetales|Rep: Uncharacterized HIT-like
           protein ML2237 - Mycobacterium leprae
          Length = 134

 Score = 44.4 bits (100), Expect = 0.003
 Identities = 32/107 (29%), Positives = 52/107 (48%), Gaps = 1/107 (0%)
 Frame = +1

Query: 244 IFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRM 423
           IF  I N+      +YEDD+V  F  I+P ++ H L +P   I+  +++   D  +  R+
Sbjct: 4   IFTKIINRELPGRFVYEDDDVVAFLTIEPMTQGHTLVVPCAEIDQWQNV---DPAIFGRV 60

Query: 424 MSISRELLSKNNLSIEDA-RFGYHWPPFRSVKHLHLHTIAPESEMGF 561
           +++S +L+ K      +A R G     F  V HLH+H     S   F
Sbjct: 61  IAVS-QLIGKGVCRAFNAERAGVIIAGF-EVPHLHIHVFPTHSLSNF 105


>UniRef50_Q9PQL9 Cluster: Probable HIT protein; n=1; Ureaplasma
           parvum|Rep: Probable HIT protein - Ureaplasma parvum
           (Ureaplasma urealyticum biotype 1)
          Length = 152

 Score = 44.0 bits (99), Expect = 0.003
 Identities = 37/118 (31%), Positives = 56/118 (47%), Gaps = 6/118 (5%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           CIFC I      ++I+ E++      DI+PAS  H+L IPK+H  +  SLT  D   L+ 
Sbjct: 4   CIFCKILKGEIISKIIDENEFAIAILDIQPASDGHMLIIPKKHYRNF-SLT--DPIYLDG 60

Query: 421 MMSISREL-LSKNNLSIEDARFGYHWPPFRS----VKHLHLHTIAPESE-MGFIGRVI 576
           MM +++ +      +      F Y      S    + H HLH I  +S   GF+ + I
Sbjct: 61  MMRLAKNMTFVLEEVFPNVLGFNYLMNSNSSAGQVIMHTHLHIIPKQSNGRGFVFKAI 118


>UniRef50_Q9SA09 Cluster: F28K20.9 protein; n=7; Magnoliophyta|Rep:
           F28K20.9 protein - Arabidopsis thaliana (Mouse-ear
           cress)
          Length = 214

 Score = 44.0 bits (99), Expect = 0.003
 Identities = 26/76 (34%), Positives = 42/76 (55%), Gaps = 3/76 (3%)
 Frame = +1

Query: 244 IFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADK---ELL 414
           IF  I  K   ++I+YED+ V  FRDI P +  H+L IPK   + + SL  A+    E+L
Sbjct: 77  IFDKIIAKEIPSDIVYEDENVLAFRDINPQAPVHVLVIPKLR-DGLTSLGKAEPRHVEVL 135

Query: 415 NRMMSISRELLSKNNL 462
            +++  S+ +  K  +
Sbjct: 136 GQLLHASKIVAEKEGI 151


>UniRef50_A5BDT4 Cluster: Putative uncharacterized protein; n=2;
           cellular organisms|Rep: Putative uncharacterized protein
           - Vitis vinifera (Grape)
          Length = 420

 Score = 44.0 bits (99), Expect = 0.003
 Identities = 22/40 (55%), Positives = 25/40 (62%)
 Frame = +1

Query: 244 IFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPK 363
           IF  I NK     I+YEDD+V  FRDI P +  HIL IPK
Sbjct: 50  IFDKIINKEIPATIVYEDDKVLAFRDIAPQAPTHILLIPK 89


>UniRef50_Q0VNN6 Cluster: HIT family protein; n=1; Alcanivorax
           borkumensis SK2|Rep: HIT family protein - Alcanivorax
           borkumensis (strain SK2 / ATCC 700651 / DSM 11573)
          Length = 150

 Score = 43.6 bits (98), Expect = 0.004
 Identities = 23/69 (33%), Positives = 35/69 (50%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           CIFC I        ++YEDD   V  D+ P    H L IP++H E +  L   D  + +R
Sbjct: 4   CIFCQIQAGTLPASVVYEDDLALVILDLFPIREAHCLVIPRQH-ESL--LEGLDAAVTHR 60

Query: 421 MMSISRELL 447
           +M ++R  +
Sbjct: 61  LMDLARRTI 69


>UniRef50_A6FN65 Cluster: HIT family protein; n=1; Roseobacter sp.
           AzwK-3b|Rep: HIT family protein - Roseobacter sp.
           AzwK-3b
          Length = 332

 Score = 43.6 bits (98), Expect = 0.004
 Identities = 33/126 (26%), Positives = 58/126 (46%), Gaps = 8/126 (6%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCV-FRDIKPASRFHILTIPKRHIEDVKSLTSADKELLN 417
           C+FC +      T+ +  ++E+CV  RD  P +  H L IPKRH+ D   L   +   + 
Sbjct: 212 CVFCELP-----TQRIVAENELCVAIRDGFPVTPMHTLIIPKRHVADYFDLYQPELNAIQ 266

Query: 418 RMMSISRELLSKNNLSIEDARFGYH--WPPFRSVKHLHLHTIA-----PESEMGFIGRVI 576
            M+   R  ++  + +++    G +      +++ H+H+H I       E   G +  VI
Sbjct: 267 TMLVEQRRQITAADDTVKGFNVGVNAGSDAGQTIFHVHVHLIPRRAGDVERPRGGVRGVI 326

Query: 577 FKKNSY 594
             K SY
Sbjct: 327 PDKQSY 332


>UniRef50_A1VWA8 Cluster: Histidine triad (HIT) protein; n=5;
           cellular organisms|Rep: Histidine triad (HIT) protein -
           Polaromonas naphthalenivorans (strain CJ2)
          Length = 133

 Score = 43.6 bits (98), Expect = 0.004
 Identities = 36/130 (27%), Positives = 58/130 (44%), Gaps = 11/130 (8%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           C FC     L  + I+ E+    +  D  P S  H L IPKRH+     +T+ ++E L  
Sbjct: 10  CPFCT----LPASRIVEENAHAVLILDGYPVSPGHSLVIPKRHVRSFFEVTAPEREALFA 65

Query: 421 MMSISRELLSKN------NLSIEDARFGYHWPPFRSVKHLHLHTIA-----PESEMGFIG 567
           ++  ++EL+++       N+ I D          ++V HLH+H I           G + 
Sbjct: 66  LLDRAKELVAEQHRPDGYNIGINDGA-----AAGQTVPHLHIHLIPRYDGDQLDPRGGVR 120

Query: 568 RVIFKKNSYW 597
            VI +K  YW
Sbjct: 121 WVIPEKADYW 130


>UniRef50_A0B7E7 Cluster: Histidine triad (HIT) protein; n=1;
           Methanosaeta thermophila PT|Rep: Histidine triad (HIT)
           protein - Methanosaeta thermophila (strain DSM 6194 /
           PT) (Methanothrixthermophila (strain DSM 6194 / PT))
          Length = 141

 Score = 43.6 bits (98), Expect = 0.004
 Identities = 19/44 (43%), Positives = 24/44 (54%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHI 372
           C+FC I    E   I+ ED+      DI P +R H L IPKRH+
Sbjct: 5   CVFCRIVRGDEPAHIIDEDELSMAILDINPLARGHCLVIPKRHV 48


>UniRef50_Q97S70 Cluster: HIT family protein; n=37;
           Streptococcaceae|Rep: HIT family protein - Streptococcus
           pneumoniae
          Length = 136

 Score = 43.2 bits (97), Expect = 0.006
 Identities = 23/101 (22%), Positives = 52/101 (51%), Gaps = 2/101 (1%)
 Frame = +1

Query: 241 CIFCNI-ANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSL-TSADKELL 414
           CIFC I A ++  +++ YED++V  F DI   +  H L +PK H  ++  +  ++  +L 
Sbjct: 4   CIFCKIIAGEIPASKV-YEDEQVLAFLDISQVTLGHTLVVPKEHYRNLLEMDATSASQLF 62

Query: 415 NRMMSISRELLSKNNLSIEDARFGYHWPPFRSVKHLHLHTI 537
            ++  ++++++     +  +          ++V H H+H +
Sbjct: 63  AQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHLV 103


>UniRef50_Q6F1M1 Cluster: Putative nucleotidyl
           hydrolase/transferase; n=2; Entomoplasmatales|Rep:
           Putative nucleotidyl hydrolase/transferase - Mesoplasma
           florum (Acholeplasma florum)
          Length = 135

 Score = 43.2 bits (97), Expect = 0.006
 Identities = 27/111 (24%), Positives = 51/111 (45%), Gaps = 3/111 (2%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           CIFC I  +   +  +YE++ V  F DI P S  H L IPK H E++ +        +++
Sbjct: 4   CIFCKIIKQEIPSYKIYENEYVYAFLDINPVSDGHALVIPKVHAENLSTTPDLYLSEVSK 63

Query: 421 MMSISRELLSKNNLSIEDARFGYHWPPF--RSVKHLHLHTIAP-ESEMGFI 564
              +  ++L +    ++   +  +      + V H H H +   + + GF+
Sbjct: 64  AKKVVAQILQEKLKGVKGFNYVSNQEAIAKQVVFHYHEHILPKFKEDEGFL 114


>UniRef50_Q0LZX4 Cluster: Histidine triad (HIT) protein precursor;
           n=2; Alphaproteobacteria|Rep: Histidine triad (HIT)
           protein precursor - Caulobacter sp. K31
          Length = 455

 Score = 43.2 bits (97), Expect = 0.006
 Identities = 26/86 (30%), Positives = 43/86 (50%), Gaps = 2/86 (2%)
 Frame = +1

Query: 286 LYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISREL--LSKNN 459
           +YEDD+V  F D  PA   H+L I K      ++L     + L+R+M+++  +     + 
Sbjct: 336 VYEDDQVLAFMDYAPAEPGHVLVISK--TSKARNLLEISPQDLSRIMAVAARVGQAQVDG 393

Query: 460 LSIEDARFGYHWPPFRSVKHLHLHTI 537
           L +E      +    +SV HLH+H I
Sbjct: 394 LGVEGFTIVQNNGVGQSVPHLHIHVI 419


>UniRef50_A5KTI5 Cluster: Histidine triad (HIT) protein; n=1;
           candidate division TM7 genomosp. GTL1|Rep: Histidine
           triad (HIT) protein - candidate division TM7 genomosp.
           GTL1
          Length = 131

 Score = 43.2 bits (97), Expect = 0.006
 Identities = 24/84 (28%), Positives = 43/84 (51%)
 Frame = +1

Query: 286 LYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLS 465
           +YEDD++  F DI PA   H L + K+ ++  + L     EL  ++M++ ++L    +  
Sbjct: 19  IYEDDDIFAFLDIYPAQPGHTLVVTKQQLDRFEELPD---ELYQKLMAVVKKLAKHLHQM 75

Query: 466 IEDARFGYHWPPFRSVKHLHLHTI 537
           ++  R       F  V H+H+H I
Sbjct: 76  LKVERITMKVEGF-DVHHVHIHLI 98


>UniRef50_A6DMK8 Cluster: Hit-like protein; n=1; Lentisphaera
           araneosa HTCC2155|Rep: Hit-like protein - Lentisphaera
           araneosa HTCC2155
          Length = 138

 Score = 42.7 bits (96), Expect = 0.008
 Identities = 20/68 (29%), Positives = 35/68 (51%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           CI+C I+   E  +I+Y+DD  C F    P +  HI+     H     SLT  + E  ++
Sbjct: 4   CIYCKISEHREHADIVYQDDTFCAFLHPTPINHGHIILTASAH---CTSLTLLEDETYSK 60

Query: 421 MMSISREL 444
           +  ++R++
Sbjct: 61  LHCLARKI 68


>UniRef50_A5KT99 Cluster: Histidine triad (HIT) protein; n=2;
           candidate division TM7 genomosp. GTL1|Rep: Histidine
           triad (HIT) protein - candidate division TM7 genomosp.
           GTL1
          Length = 497

 Score = 42.7 bits (96), Expect = 0.008
 Identities = 28/101 (27%), Positives = 52/101 (51%), Gaps = 2/101 (1%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           C+FC++ +K     I+YE + V +   +      H++ IP+RH+   K LTS + E + +
Sbjct: 31  CVFCDLRDKY----IIYEKNGVALTIILFAYIDGHLMIIPRRHVVSPKELTSLEWETIRK 86

Query: 421 MMSISRELLSKNNLSIEDARFGYH--WPPFRSVKHLHLHTI 537
            M I+++++ K    I+  +F          +V H+H H I
Sbjct: 87  FMYIAKKII-KQVHGIKGVQFVQKDGLDAQSTVGHVHYHGI 126


>UniRef50_A4XT81 Cluster: Histidine triad (HIT) protein; n=7;
           Pseudomonas aeruginosa group|Rep: Histidine triad (HIT)
           protein - Pseudomonas mendocina ymp
          Length = 148

 Score = 42.7 bits (96), Expect = 0.008
 Identities = 31/101 (30%), Positives = 43/101 (42%), Gaps = 2/101 (1%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           C+FC IA        LYED++  V  DI P    H+L + + H   +K L +A +E L  
Sbjct: 3   CVFCAIAAGQLPAHKLYEDEDFIVLLDIFPMRPAHVLIVSRVHAPYLKDLPAAARERLLA 62

Query: 421 MMSISRELLSKNNLSIEDARFGYHWPP--FRSVKHLHLHTI 537
           +       L       E      +  P   + V HLHLH I
Sbjct: 63  LADKVAAALRVAGHGREGINLLINDGPDSNQHVPHLHLHLI 103


>UniRef50_Q9PK09 Cluster: Uncharacterized HIT-like protein TC_0664;
           n=9; Chlamydiales|Rep: Uncharacterized HIT-like protein
           TC_0664 - Chlamydia muridarum
          Length = 126

 Score = 42.7 bits (96), Expect = 0.008
 Identities = 27/87 (31%), Positives = 44/87 (50%), Gaps = 3/87 (3%)
 Frame = +1

Query: 286 LYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLS 465
           ++ED+   V +D  P +  H+L IPK+HIE ++ + S D  LL+    I +  L   +  
Sbjct: 33  VFEDENFIVIKDKFPQAPVHLLIIPKKHIEKLQDMQSDDFSLLSEAGKIIQ--LMARDFG 90

Query: 466 IEDAR---FGYHWPPFRSVKHLHLHTI 537
           IE+             +SV HLH+H +
Sbjct: 91  IENGYRVVINNGLEGGQSVFHLHIHLL 117


>UniRef50_Q28QE4 Cluster: Histidine triad (HIT) protein; n=1;
           Jannaschia sp. CCS1|Rep: Histidine triad (HIT) protein -
           Jannaschia sp. (strain CCS1)
          Length = 146

 Score = 42.3 bits (95), Expect = 0.010
 Identities = 29/100 (29%), Positives = 46/100 (46%), Gaps = 1/100 (1%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           C+FC I    E   I+++D+    F  ++P      + IPK HI+     T    +L   
Sbjct: 5   CVFCRIIAGTEPASIVHDDESCLAFMILRPIREGAFIVIPKVHID---HFTDLPDDLAAH 61

Query: 421 MMSISRELLSKNNLSIEDA-RFGYHWPPFRSVKHLHLHTI 537
           +M I++    +  LS+  A R GY    F  V H HL+ +
Sbjct: 62  LMIIAQR-YGRGLLSLTPATRIGYVVHGF-GVPHAHLNVV 99


>UniRef50_A1SG63 Cluster: Histidine triad (HIT) protein; n=3;
           Actinomycetales|Rep: Histidine triad (HIT) protein -
           Nocardioides sp. (strain BAA-499 / JS614)
          Length = 142

 Score = 42.3 bits (95), Expect = 0.010
 Identities = 24/101 (23%), Positives = 50/101 (49%), Gaps = 2/101 (1%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           C+FC I       +++ E+ EV  F D +P  + H L +P+ H+  +  L +    L + 
Sbjct: 5   CVFCGIVAGEVPADLVLEETEVLGFLDRRPLFKGHTLLVPREHVVTLPDLPA---RLRDP 61

Query: 421 MMSISRELLS--KNNLSIEDARFGYHWPPFRSVKHLHLHTI 537
            ++ ++ L +  ++ L  + +    +    +SV HLH+H +
Sbjct: 62  YLAAAQRLATAMRDGLGAQGSFVAVNNVVSQSVAHLHVHVV 102


>UniRef50_A0YDE8 Cluster: Probable HIT family protein; n=1; marine
           gamma proteobacterium HTCC2143|Rep: Probable HIT family
           protein - marine gamma proteobacterium HTCC2143
          Length = 172

 Score = 42.3 bits (95), Expect = 0.010
 Identities = 20/53 (37%), Positives = 26/53 (49%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSA 399
           CIFC I         ++EDD    F DI PA+  H+L + K H  D+   T A
Sbjct: 39  CIFCQIVQGNAPCHKVHEDDLTITFLDIFPATAGHLLIVTKEHFSDLLEATPA 91


>UniRef50_Q4DJ40 Cluster: Adenosine 5'-monophosphoramidase,
           putative; n=6; Trypanosomatidae|Rep: Adenosine
           5'-monophosphoramidase, putative - Trypanosoma cruzi
          Length = 141

 Score = 42.3 bits (95), Expect = 0.010
 Identities = 32/108 (29%), Positives = 47/108 (43%), Gaps = 4/108 (3%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIE---DVKSLTSADKEL 411
           CIFC I         + E   V  F DI P SR H+L +PK H E    V+  T+AD  +
Sbjct: 4   CIFCKIVEGSIPCHRVAETARVLAFVDINPLSRGHLLIVPKAHAEFLHQVEPETAADLGV 63

Query: 412 LNRMMSISRELLSKNNLSIE-DARFGYHWPPFRSVKHLHLHTIAPESE 552
           +  M  I+R +  +     + +          + V H+H H I   +E
Sbjct: 64  M--MAKIARVVAGEGEPKTQYNVLQNNGKLAHQEVPHVHFHIIPKRNE 109


>UniRef50_Q9KDM3 Cluster: Hit-like protein involved in cell-cycle
           regulation; n=7; Bacilli|Rep: Hit-like protein involved
           in cell-cycle regulation - Bacillus halodurans
          Length = 142

 Score = 41.9 bits (94), Expect = 0.014
 Identities = 21/51 (41%), Positives = 27/51 (52%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLT 393
           CIFC I      +  +YEDD V  F DI   ++ H L IPK H  +V  L+
Sbjct: 7   CIFCKIIAGEIPSATVYEDDHVYAFLDISQVTKGHTLVIPKVHKRNVFELS 57


>UniRef50_Q8SRE4 Cluster: HIT FAMILY PROTEIN; n=1; Encephalitozoon
           cuniculi|Rep: HIT FAMILY PROTEIN - Encephalitozoon
           cuniculi
          Length = 131

 Score = 41.9 bits (94), Expect = 0.014
 Identities = 31/99 (31%), Positives = 43/99 (43%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           CIFC +  K  G  I+YE D +    D  P S+ H L IPK H      L +   E L+ 
Sbjct: 4   CIFCTLYRK--GANIIYETDRLFALIDRYPLSKGHFLVIPKAH---HPYLHNYKPEELSG 58

Query: 421 MMSISRELLSKNNLSIEDARFGYHWPPFRSVKHLHLHTI 537
           ++   R L+ K     E      +    + V H+H H I
Sbjct: 59  VLDTIRHLVQK--FGFERYNILQNNGNHQEVFHVHFHVI 95


>UniRef50_A1RYX9 Cluster: Histidine triad (HIT) protein; n=1;
           Thermofilum pendens Hrk 5|Rep: Histidine triad (HIT)
           protein - Thermofilum pendens (strain Hrk 5)
          Length = 139

 Score = 41.9 bits (94), Expect = 0.014
 Identities = 28/103 (27%), Positives = 44/103 (42%), Gaps = 4/103 (3%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           C+FC I         +Y    V VF D  P +R H L +PK H  DV     A  ++L+ 
Sbjct: 4   CVFCRIVRGQLDAHFVYVGGRVVVFLDKYPVTRGHALVVPKDHYRDV---FDAPGDVLSE 60

Query: 421 MMSISR--ELLSKNNLSIEDARFGYH--WPPFRSVKHLHLHTI 537
           M+ +++   L  +  L     R   +      + + H H+H I
Sbjct: 61  MVFVAKVVALAQREALGARGVRLVMNSGREAGQEIFHAHMHVI 103


>UniRef50_P95937 Cluster: Uncharacterized HIT-like protein SSO2163;
           n=2; Sulfolobus|Rep: Uncharacterized HIT-like protein
           SSO2163 - Sulfolobus solfataricus
          Length = 139

 Score = 41.5 bits (93), Expect = 0.018
 Identities = 18/46 (39%), Positives = 25/46 (54%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIED 378
           CIFCNI    +   I+Y +D V  F D  P +  H L +P+ H E+
Sbjct: 2   CIFCNIVEGRDHGYIVYSNDRVVAFLDKFPITPGHTLVVPRTHYEN 47


>UniRef50_P75504 Cluster: Uncharacterized 16.1 kDa HIT-like protein;
           n=2; Mycoplasma|Rep: Uncharacterized 16.1 kDa HIT-like
           protein - Mycoplasma pneumoniae
          Length = 144

 Score = 41.5 bits (93), Expect = 0.018
 Identities = 30/110 (27%), Positives = 49/110 (44%), Gaps = 4/110 (3%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           CIFC I      +  + E++    F D  P +  H L IPK+H     + +S D E L  
Sbjct: 12  CIFCGIVEGNVKSFKVGENEHAFAFLDAFPVADGHTLVIPKKH---AVNYSSTDDESLKA 68

Query: 421 MMSISRELLSKNNLSIEDARFGY----HWPPFRSVKHLHLHTIAPESEMG 558
           +  +++E+  K    ++ A   Y         + V H H+H + P+ E G
Sbjct: 69  VSLLAKEMALKLQQRLQPAGLNYVVNEGAKAGQEVFHYHMH-VVPKYETG 117


>UniRef50_Q8FTW3 Cluster: Putative uncharacterized protein; n=1;
           Corynebacterium efficiens|Rep: Putative uncharacterized
           protein - Corynebacterium efficiens
          Length = 333

 Score = 41.1 bits (92), Expect = 0.024
 Identities = 27/104 (25%), Positives = 47/104 (45%), Gaps = 5/104 (4%)
 Frame = +1

Query: 241 CIFCNI-ANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLN 417
           C FC I A        +Y +D V  F   +PA+  H L +P RH+E+V  L + +   L+
Sbjct: 17  CAFCTIIAGHDPDVREVYRNDHVVAFHPTEPATLGHTLVVPHRHVENVWDLAAEEANHLS 76

Query: 418 R----MMSISRELLSKNNLSIEDARFGYHWPPFRSVKHLHLHTI 537
           +    +    R  +    L+I  +         +++ HLH+H +
Sbjct: 77  QAVLLLSDAVRAAVHPEGLNIIQSN---GEAATQTIPHLHVHLV 117


>UniRef50_Q9JN38 Cluster: Putative HIT-like protein; n=2; Mycoplasma
           hominis|Rep: Putative HIT-like protein - Mycoplasma
           hominis
          Length = 106

 Score = 41.1 bits (92), Expect = 0.024
 Identities = 24/70 (34%), Positives = 35/70 (50%)
 Frame = +1

Query: 244 IFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRM 423
           IF  I  +    +I+YED++   F DIKP  + H L   K H     +L   D + L+ +
Sbjct: 5   IFEKIITREIPAKIIYEDEKFIAFEDIKPVDKGHFLVTVKNH---ATNLYDIDDQTLSSL 61

Query: 424 MSISRELLSK 453
           +  SREL  K
Sbjct: 62  ILKSRELALK 71


>UniRef50_A1VGI9 Cluster: Histidine triad (HIT) protein; n=2;
           Desulfovibrio vulgaris subsp. vulgaris|Rep: Histidine
           triad (HIT) protein - Desulfovibrio vulgaris subsp.
           vulgaris (strain DP4)
          Length = 139

 Score = 41.1 bits (92), Expect = 0.024
 Identities = 19/43 (44%), Positives = 21/43 (48%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRH 369
           CIFC I         LY DD V  F DI P  R H L +P+ H
Sbjct: 6   CIFCKIIRGEIPCAQLYADDHVISFMDIGPVKRGHALVVPREH 48


>UniRef50_Q9Y8Y9 Cluster: HIT family protein; n=1; Aeropyrum
           pernix|Rep: HIT family protein - Aeropyrum pernix
          Length = 149

 Score = 41.1 bits (92), Expect = 0.024
 Identities = 18/47 (38%), Positives = 25/47 (53%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDV 381
           CIFC I         +Y+ + V VF D  PAS+ H+L +P  H E +
Sbjct: 3   CIFCRIVKGEAEAYTVYKGNGVTVFLDRYPASKGHLLVVPDEHYESI 49


>UniRef50_Q8YU88 Cluster: All2466 protein; n=5; Cyanobacteria|Rep:
           All2466 protein - Anabaena sp. (strain PCC 7120)
          Length = 284

 Score = 40.7 bits (91), Expect = 0.031
 Identities = 24/69 (34%), Positives = 34/69 (49%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           CIFCN    L+   +L E        D  P S+ HIL IPKRH+ D   L   ++     
Sbjct: 166 CIFCNPHKNLK---LLTESATAYAIFDGYPISKGHILVIPKRHVSDYFELPQKEQSACWL 222

Query: 421 MMSISRELL 447
           M++ ++E L
Sbjct: 223 MVNKAQEFL 231


>UniRef50_Q4FXZ6 Cluster: Putative uncharacterized protein; n=5;
           Trypanosomatidae|Rep: Putative uncharacterized protein -
           Leishmania major strain Friedlin
          Length = 409

 Score = 40.7 bits (91), Expect = 0.031
 Identities = 27/98 (27%), Positives = 47/98 (47%), Gaps = 7/98 (7%)
 Frame = +1

Query: 274 GTEILYEDDEVCVFRDIKPASRFHILTIP-KRHIEDVKSLTSADKELLNRMMSISRELLS 450
           G+ +LY+DD   +  D  P S  H L +P    ++ + +LT  D  LL  M+ +  E + 
Sbjct: 229 GSSLLYKDDVCVLVNDAFPKSMVHCLVMPLDLRLQSLNALTKKDAPLLRHMLHVGDEYVR 288

Query: 451 KNNLSIEDA----RF--GYHWPPFRSVKHLHLHTIAPE 546
               ++       RF  G+H  P  S+  LH+H ++ +
Sbjct: 289 YLKTAVPHTYTARRFIAGFHALP--SLPMLHMHVLSTD 324


>UniRef50_Q5Z2D6 Cluster: Putative uncharacterized protein; n=1;
           Nocardia farcinica|Rep: Putative uncharacterized protein
           - Nocardia farcinica
          Length = 200

 Score = 40.3 bits (90), Expect = 0.041
 Identities = 29/111 (26%), Positives = 50/111 (45%), Gaps = 5/111 (4%)
 Frame = +1

Query: 244 IFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRM 423
           IF +I         +YED +V  F DI+P +  H+L +PK      +SL   D  +  ++
Sbjct: 60  IFSDIIAGRAPASTVYEDSDVLAFMDIRPMTPGHLLVVPK---VPARSLAELDPAIGGKL 116

Query: 424 MSISREL---LSKNNLSIEDARF--GYHWPPFRSVKHLHLHTIAPESEMGF 561
             + ++L   L  + ++ +   F         + V H+HLH I   +  GF
Sbjct: 117 FQVGQKLAAALRASEVACDGVNFFLADGVAAGQEVFHVHLHVIPRTAGDGF 167


>UniRef50_Q2LT70 Cluster: Hypothetical cytosolic protein; n=1;
           Syntrophus aciditrophicus SB|Rep: Hypothetical cytosolic
           protein - Syntrophus aciditrophicus (strain SB)
          Length = 164

 Score = 40.3 bits (90), Expect = 0.041
 Identities = 23/72 (31%), Positives = 39/72 (54%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           CIFCN+  K +  +I Y ++      D+ P +  H L +P RHIE +  LT    E+L +
Sbjct: 8   CIFCNMIAKND-YDIFYRNELFVAVVDVCPKNVGHFLILPVRHIESIYELTG--DEIL-Q 63

Query: 421 MMSISRELLSKN 456
              ++ +++S N
Sbjct: 64  FNKVALDIMSNN 75


>UniRef50_Q6SI40 Cluster: HIT family protein; n=1; uncultured
           bacterium 105|Rep: HIT family protein - uncultured
           bacterium 105
          Length = 167

 Score = 40.3 bits (90), Expect = 0.041
 Identities = 18/72 (25%), Positives = 40/72 (55%), Gaps = 1/72 (1%)
 Frame = +1

Query: 241 CIFCNI-ANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLN 417
           CIFC I  +  E T +LY+ +   +  ++ P S  H++ +PKRH+  + + T  ++  + 
Sbjct: 22  CIFCEILTDNSESTLLLYQGETCFIQLNLYPYSPGHLMVVPKRHLPSLTAATVQERMEII 81

Query: 418 RMMSISRELLSK 453
            + +++   L++
Sbjct: 82  TLTALAEVALTE 93


>UniRef50_A4YEP9 Cluster: Histidine triad (HIT) protein; n=1;
           Metallosphaera sedula DSM 5348|Rep: Histidine triad
           (HIT) protein - Metallosphaera sedula DSM 5348
          Length = 145

 Score = 40.3 bits (90), Expect = 0.041
 Identities = 16/47 (34%), Positives = 26/47 (55%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDV 381
           C+FC+I +  E    +Y D+E+    D  P++  H L +P RH  D+
Sbjct: 2   CLFCSIISGAEHGYFVYRDNEISAILDKYPSAPGHTLVMPNRHYNDL 48


>UniRef50_Q88TZ2 Cluster: Cell-cycle regulation histidine triad
           protein; n=4; Lactobacillales|Rep: Cell-cycle regulation
           histidine triad protein - Lactobacillus plantarum
          Length = 122

 Score = 39.9 bits (89), Expect = 0.055
 Identities = 28/101 (27%), Positives = 46/101 (45%), Gaps = 2/101 (1%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           CIFC      +    + E+D    F D KP S  H+L IPK H      + +A +  +  
Sbjct: 3   CIFC------QPLPYILENDLAAAFFDKKPVSPGHLLIIPKAHYATYFDVPTATRNAMLA 56

Query: 421 MMSISRELLSKNNLSIEDARFGYHWPPF--RSVKHLHLHTI 537
           +++ ++  L  +N   +    G +  P   ++V H HLH I
Sbjct: 57  LLTQAKAYLDAHN-HPDGYNIGINVDPAAGQTVMHCHLHLI 96


>UniRef50_Q2YZP9 Cluster: Putative uncharacterized protein; n=2;
           Deltaproteobacteria|Rep: Putative uncharacterized
           protein - uncultured delta proteobacterium
          Length = 162

 Score = 39.9 bits (89), Expect = 0.055
 Identities = 27/101 (26%), Positives = 46/101 (45%), Gaps = 2/101 (1%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADK-ELLN 417
           CIFC  + + +   +LY+   V V  +  P    H++ IP RH+   + LT  ++ E+ N
Sbjct: 21  CIFCKCSVRCDEF-VLYDGKNVFVMMNKYPYVNGHLMIIPNRHVGKYEELTQVERIEIFN 79

Query: 418 RMMSISRELLSKNNLSIEDARFGYHWPPFRSV-KHLHLHTI 537
            + +  + L    N S  +            V +H+HLH I
Sbjct: 80  LLETAIKALRESLNPSGFNVGMNIGKAAGAGVEEHIHLHVI 120


>UniRef50_A4VSJ7 Cluster: Diadenosine tetraphosphate (Ap4A)
           hydrolase and other HIT family hydrolases; n=12;
           Streptococcus|Rep: Diadenosine tetraphosphate (Ap4A)
           hydrolase and other HIT family hydrolases -
           Streptococcus suis (strain 05ZYH33)
          Length = 137

 Score = 39.9 bits (89), Expect = 0.055
 Identities = 29/107 (27%), Positives = 48/107 (44%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           CIFC+   ++E  +ILY+ +   V  DI P    H+L I K H + +  +    +  L+ 
Sbjct: 15  CIFCH---QIEEIDILYQTEYFKVVWDIDPIQTGHLLIISKDHYDTLSQVPPTIRYELSD 71

Query: 421 MMSISRELLSKNNLSIEDARFGYHWPPFRSVKHLHLHTIAPESEMGF 561
           +     E L +  L+I+      +   F +  H H+H I      GF
Sbjct: 72  LEVFLTEKLCQ-TLAIDGVTTACNDRLFNAGTHFHVHLIPRFRSDGF 117


>UniRef50_Q8ZTP1 Cluster: HIT family protein; n=4; Pyrobaculum|Rep:
           HIT family protein - Pyrobaculum aerophilum
          Length = 137

 Score = 39.9 bits (89), Expect = 0.055
 Identities = 18/47 (38%), Positives = 25/47 (53%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDV 381
           CIFC I         +YED+E  V  D  PAS  H+L + K+H  ++
Sbjct: 3   CIFCKIIRGEAPAWKVYEDEEFVVILDKYPASYGHVLVVSKKHFTNI 49


>UniRef50_P32083 Cluster: Uncharacterized 13.1 kDa HIT-like protein
           in P37 5'region; n=5; Mycoplasma|Rep: Uncharacterized
           13.1 kDa HIT-like protein in P37 5'region - Mycoplasma
           hyorhinis
          Length = 111

 Score = 39.9 bits (89), Expect = 0.055
 Identities = 25/99 (25%), Positives = 45/99 (45%), Gaps = 1/99 (1%)
 Frame = +1

Query: 244 IFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSAD-KELLNR 420
           +F  I  + E   ILYEDD+V  F D    ++ H L +PK +  ++ S++  D   L+ +
Sbjct: 8   LFLKIIKREEPATILYEDDKVIAFLDKYAHTKGHFLVVPKNYSRNLFSISDEDLSYLIVK 67

Query: 421 MMSISRELLSKNNLSIEDARFGYHWPPFRSVKHLHLHTI 537
               + + + K   +             +S+ H H+H I
Sbjct: 68  AREFALQEIKKLGATGFKLLINNEPDAEQSIFHTHVHII 106


>UniRef50_Q8MSG8 Cluster: Aprataxin-like protein; n=6;
           Sophophora|Rep: Aprataxin-like protein - Drosophila
           melanogaster (Fruit fly)
          Length = 662

 Score = 39.9 bits (89), Expect = 0.055
 Identities = 21/88 (23%), Positives = 41/88 (46%)
 Frame = +1

Query: 283 ILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNL 462
           ++   +   V  D  P ++ H L +P   I  +  L  +   LL  +  ++R ++    +
Sbjct: 17  LIISSEIAVVIADKFPKAQHHYLVLPLADIPSIFHLNRSHLSLLEELHLLARNVVEVKGV 76

Query: 463 SIEDARFGYHWPPFRSVKHLHLHTIAPE 546
             +D   G+H  P  S++ LHLH I+ +
Sbjct: 77  RWQDFNVGFHAEP--SMQRLHLHVISKD 102


>UniRef50_Q9RTX9 Cluster: Hit family protein; n=2; Deinococcus|Rep:
           Hit family protein - Deinococcus radiodurans
          Length = 118

 Score = 39.5 bits (88), Expect = 0.072
 Identities = 26/90 (28%), Positives = 42/90 (46%), Gaps = 2/90 (2%)
 Frame = +1

Query: 277 TEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADK--ELLNRMMSISRELLS 450
           ++++YEDD+    +DI P +  H+L IPKR    V  +T   +   L  +   I+RE   
Sbjct: 24  SQVVYEDDDYIAIKDIAPKAPIHLLVIPKRVTTRVDEITDPLEMGRLWLKATEIAREQAP 83

Query: 451 KNNLSIEDARFGYHWPPFRSVKHLHLHTIA 540
              L +     G      + V H H+H +A
Sbjct: 84  DYRLVVNCGAGG-----GQMVFHTHIHILA 108


>UniRef50_Q5CSR7 Cluster: Histidine triad (HIT) family zinc binding
           protein; n=3; Alveolata|Rep: Histidine triad (HIT)
           family zinc binding protein - Cryptosporidium parvum
           Iowa II
          Length = 130

 Score = 39.5 bits (88), Expect = 0.072
 Identities = 25/88 (28%), Positives = 43/88 (48%), Gaps = 4/88 (4%)
 Frame = +1

Query: 286 LYEDDEVCVFRDIKPASRFHILTIPKRH--IEDVKSLTSADKELLNRMMSISRELLSKNN 459
           +YEDD    F DI P +  H L +PK+   +  +   T   KE+L  +M  ++  +    
Sbjct: 35  IYEDDLCISFHDINPVAPVHALLVPKKRSGLTRLSKATETHKEILGHLM--TKVPVVAKL 92

Query: 460 LSIEDARFGYH--WPPFRSVKHLHLHTI 537
           L ++D R   +      ++V HLH+H +
Sbjct: 93  LDLDDFRIVINDGESSCQTVFHLHIHIL 120


>UniRef50_Q6YPU5 Cluster: Diadenosine tetraphosphate hydrolase; n=2;
           Candidatus Phytoplasma asteris|Rep: Diadenosine
           tetraphosphate hydrolase - Onion yellows phytoplasma
          Length = 153

 Score = 39.1 bits (87), Expect = 0.096
 Identities = 32/125 (25%), Positives = 51/125 (40%), Gaps = 1/125 (0%)
 Frame = +1

Query: 244 IFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSL-TSADKELLNR 420
           IF  I  K     +LYED+ V  F DI  A++ H L +PK+   D+  +       L   
Sbjct: 18  IFTKIIKKQVPGYLLYEDNLVVAFLDIAQATKGHTLVVPKQEYRDILMMPEDVFAHLFKV 77

Query: 421 MMSISRELLSKNNLSIEDARFGYHWPPFRSVKHLHLHTIAPESEMGFIGRVIFKKNSYWF 600
           +  IS+ L+        +          ++V H H+H I    E      ++FK N+   
Sbjct: 78  VHQISKALMDVFQAQGINLLNNNGKVAGQTVFHYHVHLIPRFDEKEI--NLVFKNNASLM 135

Query: 601 VSPEY 615
              +Y
Sbjct: 136 FPQDY 140


>UniRef50_Q6NFF8 Cluster: HIT family protein; n=4;
           Corynebacterium|Rep: HIT family protein -
           Corynebacterium diphtheriae
          Length = 141

 Score = 39.1 bits (87), Expect = 0.096
 Identities = 26/105 (24%), Positives = 48/105 (45%)
 Frame = +1

Query: 244 IFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRM 423
           +F  I N       +Y D  +  F  I+P +  H+L +P   +++V   T  + EL   +
Sbjct: 4   VFTKIINGDLPGRFVYRDAHIVAFLTIEPLAYGHVLVVP---VKEVDKWTDLEPELWTEL 60

Query: 424 MSISRELLSKNNLSIEDARFGYHWPPFRSVKHLHLHTIAPESEMG 558
            +++ ++      + +  R GY    F  V H H+H + P  +MG
Sbjct: 61  NAVALKVGQAVVSAFDAPRAGYIIAGF-DVPHTHIH-VFPAGKMG 103


>UniRef50_A6G534 Cluster: HIT-family protein; n=1; Plesiocystis
           pacifica SIR-1|Rep: HIT-family protein - Plesiocystis
           pacifica SIR-1
          Length = 141

 Score = 39.1 bits (87), Expect = 0.096
 Identities = 25/92 (27%), Positives = 41/92 (44%), Gaps = 1/92 (1%)
 Frame = +1

Query: 286 LYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMM-SISRELLSKNNL 462
           +YEDD+V  F DI P +  H L IPK+    +  L       L R +  ++R +++   +
Sbjct: 20  VYEDDQVLAFLDIAPLAPGHTLVIPKQRRAFLHELDDEVAAALGRALPRVARAVMAATGV 79

Query: 463 SIEDARFGYHWPPFRSVKHLHLHTIAPESEMG 558
              +          ++V H+H H I    E G
Sbjct: 80  PEYNVLQNNGSSAHQAVFHVHFHIIPRVGEHG 111


>UniRef50_Q57WA7 Cluster: Putative uncharacterized protein; n=1;
           Trypanosoma brucei|Rep: Putative uncharacterized protein
           - Trypanosoma brucei
          Length = 258

 Score = 39.1 bits (87), Expect = 0.096
 Identities = 28/98 (28%), Positives = 46/98 (46%), Gaps = 10/98 (10%)
 Frame = +1

Query: 277 TEILYEDDEVCVFRDIKPASRFHILTIP-KRHIEDVKSLTSADKELLNRMMSI------- 432
           + +LY+D +  +  D  P SR H L IP    ++ + +L      LL  +M +       
Sbjct: 70  SHVLYKDPQCIIVNDAYPKSRLHCLVIPLDLSLDSLSALRPNHVPLLQHLMEVAEQYVQF 129

Query: 433 SRELLSKNNLSIEDARF--GYHWPPFRSVKHLHLHTIA 540
           +RE  + N   I+   F  G+H  P  S+  LH+H I+
Sbjct: 130 TREDAASNEAGIQALSFMTGFHSLP--SLPQLHMHLIS 165


>UniRef50_Q04344 Cluster: Hit family protein 1; n=22; Dikarya|Rep:
           Hit family protein 1 - Saccharomyces cerevisiae (Baker's
           yeast)
          Length = 158

 Score = 39.1 bits (87), Expect = 0.096
 Identities = 30/104 (28%), Positives = 38/104 (36%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           CIFC I      +  L E      F DI+P +  H L IPK H      L     E L  
Sbjct: 25  CIFCKIIKSEIPSFKLIETKYSYAFLDIQPTAEGHALIIPKYH---GAKLHDIPDEFLTD 81

Query: 421 MMSISRELLSKNNLSIEDARFGYHWPPFRSVKHLHLHTIAPESE 552
            M I++ L     L   +          + V H+H H I    E
Sbjct: 82  AMPIAKRLAKAMKLDTYNVLQNNGKIAHQEVDHVHFHLIPKRDE 125


>UniRef50_A7R099 Cluster: Chromosome undetermined scaffold_300,
           whole genome shotgun sequence; n=4; core
           eudicotyledons|Rep: Chromosome undetermined
           scaffold_300, whole genome shotgun sequence - Vitis
           vinifera (Grape)
          Length = 195

 Score = 38.7 bits (86), Expect = 0.13
 Identities = 25/100 (25%), Positives = 39/100 (39%), Gaps = 1/100 (1%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVK-SLTSADKELLN 417
           C+FC I         LYEDD      D  P S  H L IPK H   ++ +  S    + +
Sbjct: 41  CVFCKIIRGQSPALKLYEDDMCLCILDTHPLSHGHSLIIPKSHFSSLEMTPPSVVAAMCS 100

Query: 418 RMMSISRELLSKNNLSIEDARFGYHWPPFRSVKHLHLHTI 537
           ++  IS  ++        +          + + H H+H I
Sbjct: 101 KVPFISNAIMKATGCDSFNLLVNNGAAAGQVIFHTHIHII 140


>UniRef50_A7TKH2 Cluster: Putative uncharacterized protein; n=1;
           Vanderwaltozyma polyspora DSM 70294|Rep: Putative
           uncharacterized protein - Vanderwaltozyma polyspora DSM
           70294
          Length = 308

 Score = 38.7 bits (86), Expect = 0.13
 Identities = 27/102 (26%), Positives = 51/102 (50%), Gaps = 10/102 (9%)
 Frame = +1

Query: 262 NKLEGTEILYEDDEVCVFRDIK----PASRFHILTIPKRHIEDVKSLTSADK---ELLNR 420
           N  E   ++Y+DD++ +  D+K        F++++I KR  +D+ SL   +K   E LN 
Sbjct: 150 NGAESDRVVYQDDDMVILPDMKWDGENMDAFYLVSILKR--KDILSLRDINKNHYEFLNG 207

Query: 421 MMSISRELLSK---NNLSIEDARFGYHWPPFRSVKHLHLHTI 537
           +    ++++ K   N +  +  R   H+ P  S  H H+H +
Sbjct: 208 ISERIKDIIPKKYNNEIKSDQLRIFIHYQP--SYYHFHIHIV 247


>UniRef50_P64382 Cluster: Uncharacterized HIT-like protein HP_0404;
           n=4; Helicobacter|Rep: Uncharacterized HIT-like protein
           HP_0404 - Helicobacter pylori (Campylobacter pylori)
          Length = 104

 Score = 38.7 bits (86), Expect = 0.13
 Identities = 24/87 (27%), Positives = 42/87 (48%), Gaps = 2/87 (2%)
 Frame = +1

Query: 286 LYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLS 465
           + E++    F DI P ++ H L IPK+ I+D   +T    EL+ +M S   E++ K  + 
Sbjct: 17  ILENERFLSFYDINPKAKVHALVIPKQSIQDFNGIT---PELMAQMTSFIFEVVEKLGIK 73

Query: 466 IEDARF--GYHWPPFRSVKHLHLHTIA 540
            +  +          + V HLH H ++
Sbjct: 74  EKGYKLLTNVGKNAGQEVMHLHFHILS 100


>UniRef50_Q1V185 Cluster: Histidine triad (HIT) protein; n=3;
           Bacteria|Rep: Histidine triad (HIT) protein - Candidatus
           Pelagibacter ubique HTCC1002
          Length = 121

 Score = 38.3 bits (85), Expect = 0.17
 Identities = 31/109 (28%), Positives = 49/109 (44%), Gaps = 8/109 (7%)
 Frame = +1

Query: 244 IFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLT--SADKELLN 417
           IF  I  K    + ++E++ V  F DI P  + H L IPK    D+      ++D+E++ 
Sbjct: 8   IFAKILRKEIPCKKIFENEYVLSFHDISPQKKIHALVIPKGEYIDLDDFNARASDQEIIA 67

Query: 418 RMMSISRELLSKNNLSIEDARFGYH------WPPFRSVKHLHLHTIAPE 546
              +IS E+    N+S +  + GY           + V HLH H    E
Sbjct: 68  LSKAIS-EVSKILNISTDTGK-GYRALTNLSEDGGQEVPHLHFHLFGGE 114


>UniRef50_Q1QBU6 Cluster: Histidine triad (HIT) protein; n=2;
           Psychrobacter|Rep: Histidine triad (HIT) protein -
           Psychrobacter cryohalolentis (strain K5)
          Length = 146

 Score = 38.3 bits (85), Expect = 0.17
 Identities = 25/91 (27%), Positives = 44/91 (48%), Gaps = 7/91 (7%)
 Frame = +1

Query: 286 LYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSL----TSADKELLNRMMSISRELLSK 453
           +YEDD+   F DI P ++ H+L IPK+   D+  L     +A      ++M   R++ ++
Sbjct: 29  VYEDDKTLAFMDIMPQAKGHVLVIPKQKAVDLADLEPEYAAAVLMTAKKVMEAQRQVFNR 88

Query: 454 N---NLSIEDARFGYHWPPFRSVKHLHLHTI 537
                + +  A  G      ++V H H+H I
Sbjct: 89  EGIVQMQLNGAEAG------QTVFHYHVHLI 113


>UniRef50_A7BDL4 Cluster: Putative uncharacterized protein; n=1;
           Actinomyces odontolyticus ATCC 17982|Rep: Putative
           uncharacterized protein - Actinomyces odontolyticus ATCC
           17982
          Length = 148

 Score = 38.3 bits (85), Expect = 0.17
 Identities = 27/103 (26%), Positives = 44/103 (42%)
 Frame = +1

Query: 244 IFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRM 423
           IF NI   +     ++ DD    F  I+P S  H+L +P+   +   + T A  ++   +
Sbjct: 4   IFDNIITGVWPGRFVWADDVCVAFATIEPTSPGHVLVVPRTAYD---AWTDAPSDVAAHL 60

Query: 424 MSISRELLSKNNLSIEDARFGYHWPPFRSVKHLHLHTIAPESE 552
           M+++R +      +    R G     F  V H HLH I    E
Sbjct: 61  MTVARTIGLAQKAAFGVPRAGLAIAGF-EVPHTHLHVIPLRDE 102


>UniRef50_A6DCA2 Cluster: Histidine triad (HIT) protein; n=1;
           Caminibacter mediatlanticus TB-2|Rep: Histidine triad
           (HIT) protein - Caminibacter mediatlanticus TB-2
          Length = 160

 Score = 38.3 bits (85), Expect = 0.17
 Identities = 21/58 (36%), Positives = 30/58 (51%), Gaps = 4/58 (6%)
 Frame = +1

Query: 241 CIFCNIANKLE---GTEILYEDDEVCVF-RDIKPASRFHILTIPKRHIEDVKSLTSAD 402
           C+FC IA   E     E+ Y DD +C F  +  P +  H + IP RHI + + LT  +
Sbjct: 20  CVFCEIAKSSEFDDENEVFYRDD-ICYFVMNRFPYNPGHFMIIPNRHIANYEDLTDEE 76


>UniRef50_A5I340 Cluster: Hit family protein; n=4; Clostridium
           botulinum|Rep: Hit family protein - Clostridium
           botulinum A str. ATCC 3502
          Length = 125

 Score = 38.3 bits (85), Expect = 0.17
 Identities = 31/105 (29%), Positives = 47/105 (44%), Gaps = 6/105 (5%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           C+FCN       TEI+ E+       D  P +  H L I KRH     S   A +E +  
Sbjct: 4   CVFCNY----NSTEIIAENRVAFAILDKFPVNEGHTLIISKRHF---NSFFEATEEEVKG 56

Query: 421 MMSISRELLSKNNLSIEDARFGYH------WPPFRSVKHLHLHTI 537
           + S+  E+  K  L I+    GY+      +   +++ HLH+H I
Sbjct: 57  IYSLMHEV--KEMLDIQYEPTGYNVGVNIGYDAGQTIMHLHIHLI 99


>UniRef50_A5CF29 Cluster: Protein kinase C inhibitor 1; n=1;
           Orientia tsutsugamushi Boryong|Rep: Protein kinase C
           inhibitor 1 - Orientia tsutsugamushi (strain Boryong)
           (Rickettsia tsutsugamushi)
          Length = 123

 Score = 38.3 bits (85), Expect = 0.17
 Identities = 25/102 (24%), Positives = 43/102 (42%), Gaps = 3/102 (2%)
 Frame = +1

Query: 244 IFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPK-RHIEDVKSLTSADKELLNR 420
           +F  I        I+Y+D+++  F DI P S  HIL IP   +I+    L+ A  + +  
Sbjct: 15  VFAKILRNELSANIVYKDNKILAFHDINPISSTHILVIPNGEYIDYCDFLSKASPDDICH 74

Query: 421 MMSISRELLSKNNLSIEDARFGYH--WPPFRSVKHLHLHTIA 540
             S    ++ +  L     +   H      + + H H H I+
Sbjct: 75  YFSTINSMVKQFKLDQSGFKLVTHNGKGGGQEIPHFHTHIIS 116


>UniRef50_A6S7H6 Cluster: Predicted protein; n=2;
           Sclerotiniaceae|Rep: Predicted protein - Botryotinia
           fuckeliana B05.10
          Length = 220

 Score = 38.3 bits (85), Expect = 0.17
 Identities = 20/54 (37%), Positives = 29/54 (53%)
 Frame = +1

Query: 286 LYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELL 447
           LYE ++V  F DI P SR H L IPK H E    L     + L  ++ + ++L+
Sbjct: 111 LYESEKVLAFLDINPLSRGHALVIPKHHGE---KLVDIPDDQLEEILPVVKKLV 161


>UniRef50_Q7MKL5 Cluster: Diadenosine tetraphosphate hydrolase; n=7;
           Gammaproteobacteria|Rep: Diadenosine tetraphosphate
           hydrolase - Vibrio vulnificus (strain YJ016)
          Length = 138

 Score = 37.9 bits (84), Expect = 0.22
 Identities = 25/97 (25%), Positives = 41/97 (42%), Gaps = 5/97 (5%)
 Frame = +1

Query: 256 IANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSIS 435
           I N+   + I+YE D+V  F D  P +  HIL  PK      ++     + +L  +  ++
Sbjct: 13  IVNREIDSVIVYESDQVIAFADHDPINFGHILICPK---AQYRTFIDLPESVLFEITDVA 69

Query: 436 RELLSKNNLSIEDARFGY-----HWPPFRSVKHLHLH 531
           R+L  +          G+       P F  + H HLH
Sbjct: 70  RDLYKRIEAKFNPDGIGFMQNNGEAPHFNELDHYHLH 106


>UniRef50_Q31N56 Cluster: Putative uncharacterized protein; n=2;
           Synechococcus elongatus|Rep: Putative uncharacterized
           protein - Synechococcus sp. (strain PCC 7942) (Anacystis
           nidulans R2)
          Length = 142

 Score = 37.9 bits (84), Expect = 0.22
 Identities = 20/58 (34%), Positives = 32/58 (55%)
 Frame = +1

Query: 280 EILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSK 453
           E+L E+D    FRD  P S  H L +PKR +  +  L +A+ +    +++I R LL +
Sbjct: 15  ELLAENDWAVAFRDRYPVSPGHSLVVPKRAVGSLFELPTAEFQASWELVAIVRSLLQQ 72


>UniRef50_A2E0S0 Cluster: HIT domain containing protein; n=1;
           Trichomonas vaginalis G3|Rep: HIT domain containing
           protein - Trichomonas vaginalis G3
          Length = 135

 Score = 37.9 bits (84), Expect = 0.22
 Identities = 27/88 (30%), Positives = 44/88 (50%), Gaps = 3/88 (3%)
 Frame = +1

Query: 283 ILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADK-ELLNRMMSISRELLSKNN 459
           I YE +    F +++PA   H+L  PKR ++    LT A+K +LLN    + R+ + K +
Sbjct: 18  IFYESELSFAFVNLRPACEGHVLISPKRVVQFFDLLTDAEKLDLLNTATHV-RDTM-KAS 75

Query: 460 LSIEDARFGYHWPPF--RSVKHLHLHTI 537
           +  E         P   ++V H+H H I
Sbjct: 76  MHTEGCAMTIQDGPAAGQTVPHVHFHVI 103


>UniRef50_UPI0000DBEF88 Cluster: UPI0000DBEF88 related cluster; n=1;
           Rattus norvegicus|Rep: UPI0000DBEF88 UniRef100 entry -
           Rattus norvegicus
          Length = 133

 Score = 37.5 bits (83), Expect = 0.29
 Identities = 30/108 (27%), Positives = 49/108 (45%), Gaps = 10/108 (9%)
 Frame = +1

Query: 244 IFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHI-------EDVKSLTSAD 402
           IF  I  K    +I+ ED +   F+ I P    H L IPK+HI       E++  ++ AD
Sbjct: 18  IFSKIICKEIPAKIVLEDYQCLAFQGISPQVPTHFLVIPKKHINIFNEKKENISQISEAD 77

Query: 403 ---KELLNRMMSISRELLSKNNLSIEDARFGYHWPPFRSVKHLHLHTI 537
              + LL  +M + ++      L ++           +SV H+HLH +
Sbjct: 78  DDNESLLGHLMIVGKKCAV--YLGLKHWMVVNECVDGQSVYHIHLHVL 123


>UniRef50_A6Q3Z1 Cluster: Histidine triad family protein; n=16;
           Epsilonproteobacteria|Rep: Histidine triad family
           protein - Nitratiruptor sp. (strain SB155-2)
          Length = 165

 Score = 37.5 bits (83), Expect = 0.29
 Identities = 26/105 (24%), Positives = 48/105 (45%), Gaps = 6/105 (5%)
 Frame = +1

Query: 241 CIFCNIANKLEGTE---ILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKEL 411
           C+FC +    E  E   +LY      V  +  P +  H + IP +HI+++++L+    E 
Sbjct: 22  CVFCYVVEHPEEDEELGVLYRAKYSFVVMNKYPYTPGHFMVIPNQHIDNLENLSEEAWEE 81

Query: 412 LNRMMSISRELLSKNNLSIEDARFGYHWPPFRS---VKHLHLHTI 537
           ++R+      LL K+ L  E    G +          +H+H+H +
Sbjct: 82  MSRLTKRGVALL-KDVLHAEGVNIGMNLGAAAGAGIAEHIHMHLV 125


>UniRef50_A5UPG3 Cluster: Histidine triad (HIT) protein; n=5;
           Chloroflexi (class)|Rep: Histidine triad (HIT) protein -
           Roseiflexus sp. RS-1
          Length = 138

 Score = 37.5 bits (83), Expect = 0.29
 Identities = 17/32 (53%), Positives = 19/32 (59%)
 Frame = +1

Query: 286 LYEDDEVCVFRDIKPASRFHILTIPKRHIEDV 381
           +YEDDE   F DI PASR H L I K    D+
Sbjct: 18  VYEDDETLAFMDINPASRGHTLVICKEEHPDI 49


>UniRef50_A0RX45 Cluster: Asymmetrical
           bis(5'-nucleosyl)-tetraphosphatase; n=2;
           Thermoprotei|Rep: Asymmetrical
           bis(5'-nucleosyl)-tetraphosphatase - Cenarchaeum
           symbiosum
          Length = 141

 Score = 37.5 bits (83), Expect = 0.29
 Identities = 25/100 (25%), Positives = 39/100 (39%), Gaps = 1/100 (1%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSL-TSADKELLN 417
           CIFC I         +Y D       D  P    H L IP+ H E +  +   A  +L +
Sbjct: 4   CIFCEIIRGGRRGAFVYRDGGAIAILDKYPIDLGHCLVIPREHHETIGEMDPRAVGDLFS 63

Query: 418 RMMSISRELLSKNNLSIEDARFGYHWPPFRSVKHLHLHTI 537
           R+  I+R +++                  + V H+H+H I
Sbjct: 64  RVPKIARAVVAGTGADAFSIAQNNGRAARQIVPHVHIHII 103


>UniRef50_Q3A4F7 Cluster: HIT (HINT, histidine triad) family
           protein; n=1; Pelobacter carbinolicus DSM 2380|Rep: HIT
           (HINT, histidine triad) family protein - Pelobacter
           carbinolicus (strain DSM 2380 / Gra Bd 1)
          Length = 165

 Score = 37.1 bits (82), Expect = 0.39
 Identities = 23/82 (28%), Positives = 41/82 (50%), Gaps = 6/82 (7%)
 Frame = +1

Query: 241 CIFC--NIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADK--- 405
           C+FC  +I  +     IL+  + V V  +  P +  H+L  P RH+ D+  L SA++   
Sbjct: 24  CVFCVRDIQGEDAQRLILWRGEHVFVVMNKYPYTNGHLLIAPYRHVPDILDLESAEEVEM 83

Query: 406 -ELLNRMMSISRELLSKNNLSI 468
            +LL +   + +E L  +  +I
Sbjct: 84  FQLLRKCRRVLQECLKPHGFNI 105


>UniRef50_Q10MW4 Cluster: Basic helix-loop-helix, putative,
           expressed; n=4; Oryza sativa|Rep: Basic
           helix-loop-helix, putative, expressed - Oryza sativa
           subsp. japonica (Rice)
          Length = 572

 Score = 37.1 bits (82), Expect = 0.39
 Identities = 31/102 (30%), Positives = 48/102 (47%), Gaps = 7/102 (6%)
 Frame = +1

Query: 262 NKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKE---LLNRMMSI 432
           N      +L   D+  V  D+ P ++ H+L + ++  + + SL    KE   LL RM S 
Sbjct: 381 NYKNSDSLLEISDDFVVLNDLYPKAKRHVLVVSRK--DGLDSLADVKKEHLPLLRRMHSA 438

Query: 433 SRELLSKNNLSIEDA----RFGYHWPPFRSVKHLHLHTIAPE 546
             +   K     ED+    R GYH  P  S++ LHLH I+ +
Sbjct: 439 GVKWAQK--FLEEDSSLVFRLGYHSVP--SMRQLHLHIISQD 476


>UniRef50_A1RZ81 Cluster: Galactose-1-phosphate uridylyltransferase;
           n=1; Thermofilum pendens Hrk 5|Rep:
           Galactose-1-phosphate uridylyltransferase - Thermofilum
           pendens (strain Hrk 5)
          Length = 338

 Score = 37.1 bits (82), Expect = 0.39
 Identities = 25/101 (24%), Positives = 47/101 (46%), Gaps = 4/101 (3%)
 Frame = +1

Query: 241 CIFCNIAN--KLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELL 414
           C+FC++      EG   +YE++   VF        + +   PKRH+  + +L+S ++  L
Sbjct: 175 CLFCHVLELEAEEGARTVYENEHFLVFLPFFAMWPYELHVYPKRHVGSLNTLSSDERVSL 234

Query: 415 NRMMSISRELLSKNNLSIEDARF--GYHWPPFRSVKHLHLH 531
              + ++  + + N+L      +   +H  P R    LHLH
Sbjct: 235 ADALRVT--VAAYNSLFGFSLPYIMVFHQSPCRDEGSLHLH 273


>UniRef50_Q03D63 Cluster: Diadenosine tetraphosphate (Ap4A)
           hydrolase related HIT family hydrolase; n=1; Pediococcus
           pentosaceus ATCC 25745|Rep: Diadenosine tetraphosphate
           (Ap4A) hydrolase related HIT family hydrolase -
           Pediococcus pentosaceus (strain ATCC 25745 / 183-1w)
          Length = 132

 Score = 36.7 bits (81), Expect = 0.51
 Identities = 23/100 (23%), Positives = 43/100 (43%), Gaps = 1/100 (1%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           C+FC    +    + + E+     F D  P S+ H L +PKRH+  +  L   ++  +  
Sbjct: 7   CVFCQKTKE----DYIVENKLAASFLDFYPVSKGHTLIVPKRHVRQLWELNEEERHAIFT 62

Query: 421 MMSISRELL-SKNNLSIEDARFGYHWPPFRSVKHLHLHTI 537
           ++  ++ +L  K      +          +SV H H+H I
Sbjct: 63  LVEKNKAILDQKYQPDGYNVVVNSGAAAGQSVFHCHIHLI 102


>UniRef50_Q5B6X2 Cluster: Putative uncharacterized protein; n=2;
           Trichocomaceae|Rep: Putative uncharacterized protein -
           Emericella nidulans (Aspergillus nidulans)
          Length = 188

 Score = 36.7 bits (81), Expect = 0.51
 Identities = 16/28 (57%), Positives = 19/28 (67%)
 Frame = +1

Query: 286 LYEDDEVCVFRDIKPASRFHILTIPKRH 369
           L+E D+V  F DI+P SR H L IPK H
Sbjct: 31  LFESDKVFAFLDIQPLSRGHALVIPKYH 58


>UniRef50_Q979C0 Cluster: Histidine triad protein [HIT]; n=3;
           Thermoplasma|Rep: Histidine triad protein [HIT] -
           Thermoplasma volcanium
          Length = 157

 Score = 36.7 bits (81), Expect = 0.51
 Identities = 21/80 (26%), Positives = 38/80 (47%), Gaps = 4/80 (5%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRH---IEDVKSLTSAD-KE 408
           C+FC    +     ++ E++    F D  P    H+L IPKRH   I D+      + ++
Sbjct: 12  CVFCTEIIQKRNAAVVAENEYTIAFMDKAPVEPGHVLVIPKRHFINIFDIDDFYYIEVQK 71

Query: 409 LLNRMMSISRELLSKNNLSI 468
           ++ R+     E LS + L++
Sbjct: 72  MVKRVSKAVLEALSADALNV 91


>UniRef50_Q8YHI2 Cluster: BIS(5'-NUCLEOSYL)-TETRAPHOSPHATASE; n=29;
           Proteobacteria|Rep: BIS(5'-NUCLEOSYL)-TETRAPHOSPHATASE -
           Brucella melitensis
          Length = 149

 Score = 36.3 bits (80), Expect = 0.67
 Identities = 23/89 (25%), Positives = 46/89 (51%), Gaps = 5/89 (5%)
 Frame = +1

Query: 286 LYEDDEVCVFRDIKPASRFHILTIPK---RHIEDVKSLTSADK-ELLNRMMSISRELLSK 453
           +YE D V  F D+ P  + H L +PK   R++ D +  T AD  + + ++ +  ++  + 
Sbjct: 33  VYETDSVVAFMDVMPQGKGHTLVVPKAPSRNLLDARPETLADVIQAVQKIANAVKKAFNA 92

Query: 454 NNLSIEDARFGYHWPPF-RSVKHLHLHTI 537
           + +++      ++ P   ++V HLH H I
Sbjct: 93  DGVTV----MQFNEPASGQTVYHLHFHVI 117


>UniRef50_Q7M8Z0 Cluster: HIT-FAMILY PROTEIN; n=12;
           Epsilonproteobacteria|Rep: HIT-FAMILY PROTEIN -
           Wolinella succinogenes
          Length = 120

 Score = 36.3 bits (80), Expect = 0.67
 Identities = 23/88 (26%), Positives = 41/88 (46%), Gaps = 4/88 (4%)
 Frame = +1

Query: 286 LYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLS 465
           ++E+ +   F DI P +  H+L IPK+     +S    D   +  M S  +E+  K  L 
Sbjct: 17  VHENSDFLAFHDINPKAPIHVLAIPKK---CARSFQEVDPSWMGGMTSFIQEVARK--LG 71

Query: 466 IEDARF----GYHWPPFRSVKHLHLHTI 537
           +++A +       +   + V HLH H +
Sbjct: 72  LDEAGYRVITNIGYDGGQEVPHLHFHIL 99


>UniRef50_Q3K5R5 Cluster: Histidine triad (HIT) protein; n=9;
           Bacteria|Rep: Histidine triad (HIT) protein -
           Pseudomonas fluorescens (strain PfO-1)
          Length = 154

 Score = 36.3 bits (80), Expect = 0.67
 Identities = 24/95 (25%), Positives = 42/95 (44%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           CIFC+IA+      +++E +    F  I P +    + IPK H     +   +D+ L   
Sbjct: 3   CIFCDIASGKAPAHVIWESESHLAFLSICPNTPGFTVVIPKAHASSY-AFAQSDQALTEL 61

Query: 421 MMSISRELLSKNNLSIEDARFGYHWPPFRSVKHLH 525
            ++     L  ++   + AR G  +  +  V HLH
Sbjct: 62  TLAAKAVALLLDSALPDVARTGMMFEGY-GVDHLH 95


>UniRef50_A3HA11 Cluster: Histidine triad (HIT) protein; n=1;
           Caldivirga maquilingensis IC-167|Rep: Histidine triad
           (HIT) protein - Caldivirga maquilingensis IC-167
          Length = 177

 Score = 35.9 bits (79), Expect = 0.89
 Identities = 21/74 (28%), Positives = 34/74 (45%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           C  C   N  +   ++Y  +   V  +  P +R H+L  PKRH+  +  LT  D+EL+  
Sbjct: 26  CFMCRAVNSNDEL-VVYRGNYCIVIMNKYPYNRGHLLIAPKRHVPGIVDLT--DEELMEC 82

Query: 421 MMSISRELLSKNNL 462
            M I     + + L
Sbjct: 83  AMLIKASTCALSEL 96


>UniRef50_A3H762 Cluster: Galactose-1-phosphate uridylyltransferase;
           n=4; Archaea|Rep: Galactose-1-phosphate
           uridylyltransferase - Caldivirga maquilingensis IC-167
          Length = 327

 Score = 35.9 bits (79), Expect = 0.89
 Identities = 24/101 (23%), Positives = 47/101 (46%), Gaps = 4/101 (3%)
 Frame = +1

Query: 241 CIFCNIANKLE--GTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELL 414
           C+ C+I ++    G  +LY + E  V +       + I  IP+RH++ +  LT  D EL+
Sbjct: 172 CLLCSILDEEVKLGERVLYTNGEFYVVKPYYSMWPYEIHVIPRRHVQKMTQLT--DDELV 229

Query: 415 NRMMSISRELLSKNNLSIEDARF--GYHWPPFRSVKHLHLH 531
               ++       +N+   D  +   +H  P ++ +  H+H
Sbjct: 230 KLADALRVTTAMLDNVLGRDMPYIMAFHQGPVKNDESYHMH 270


>UniRef50_P49776 Cluster: Bis(5'-nucleosyl)-tetraphosphatase
           [asymmetrical]; n=1; Schizosaccharomyces pombe|Rep:
           Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] -
           Schizosaccharomyces pombe (Fission yeast)
          Length = 182

 Score = 35.9 bits (79), Expect = 0.89
 Identities = 22/97 (22%), Positives = 45/97 (46%), Gaps = 1/97 (1%)
 Frame = +1

Query: 274 GTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSAD-KELLNRMMSISRELLS 450
           G+++ Y       F ++KP    H+L IP+R +  +K LT ++  +L   +  + + +  
Sbjct: 13  GSQVFYRTKLSAAFVNLKPILPGHVLVIPQRAVPRLKDLTPSELTDLFTSVRKVQQVIEK 72

Query: 451 KNNLSIEDARFGYHWPPFRSVKHLHLHTIAPESEMGF 561
             + S  +          ++V H+H+H I P  +  F
Sbjct: 73  VFSASASNIGIQDGVDAGQTVPHVHVH-IIPRKKADF 108


>UniRef50_A1WAF8 Cluster: Histidine triad (HIT) protein; n=5;
           Betaproteobacteria|Rep: Histidine triad (HIT) protein -
           Acidovorax sp. (strain JS42)
          Length = 143

 Score = 35.5 bits (78), Expect = 1.2
 Identities = 28/111 (25%), Positives = 45/111 (40%), Gaps = 5/111 (4%)
 Frame = +1

Query: 241 CIFCN-IANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELL- 414
           CIFC  +A ++   ++ YED     F DI   +  H+L   KRH   +   T  +   L 
Sbjct: 11  CIFCRLVAGEIPSAKV-YEDALTIAFMDIGQVTPGHVLVATKRHAATLLDTTPEEAAALM 69

Query: 415 ---NRMMSISRELLSKNNLSIEDARFGYHWPPFRSVKHLHLHTIAPESEMG 558
               R+    R       L++  A         ++V H+HLH +    + G
Sbjct: 70  QTARRVALAVRTAFDPPGLTLLQANGALGG---QTVAHVHLHVVPRHEDDG 117


>UniRef50_Q3E2P9 Cluster: Galactose-1-phosphate uridylyltransferase;
           n=2; Chloroflexus|Rep: Galactose-1-phosphate
           uridylyltransferase - Chloroflexus aurantiacus J-10-fl
          Length = 329

 Score = 35.1 bits (77), Expect = 1.6
 Identities = 22/83 (26%), Positives = 41/83 (49%), Gaps = 2/83 (2%)
 Frame = +1

Query: 241 CIFCN-IANKLEGTE-ILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELL 414
           C+FC  +A++L   E I+Y +D+   F     +S FHI  +P++H      +  A+   L
Sbjct: 195 CVFCTMLADELAQRERIVYANDDFVAFVLYAASSPFHIWVLPRKHRASFFHIAEAE---L 251

Query: 415 NRMMSISRELLSKNNLSIEDARF 483
           + +  + RE+  +    + D  F
Sbjct: 252 DGLADVVREVFHRLYYRLNDPDF 274


>UniRef50_A4AKY1 Cluster: Putative uncharacterized protein; n=1;
           marine actinobacterium PHSC20C1|Rep: Putative
           uncharacterized protein - marine actinobacterium
           PHSC20C1
          Length = 153

 Score = 35.1 bits (77), Expect = 1.6
 Identities = 26/96 (27%), Positives = 39/96 (40%)
 Frame = +1

Query: 244 IFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRM 423
           IF  I N       ++ DD +     I+P    H+L IP+  I+    L   D+EL   +
Sbjct: 4   IFTEILNGRSPGRFIWADDRLFAILTIEPRKPGHVLVIPRVEIDRWSEL---DEELAMHI 60

Query: 424 MSISRELLSKNNLSIEDARFGYHWPPFRSVKHLHLH 531
             + R +           R G  +  +R V H HLH
Sbjct: 61  FRVGRLIGLAQREEWNADRVGLMFEGYR-VPHAHLH 95


>UniRef50_A7QKZ8 Cluster: Chromosome chr8 scaffold_115, whole genome
           shotgun sequence; n=2; Vitis vinifera|Rep: Chromosome
           chr8 scaffold_115, whole genome shotgun sequence - Vitis
           vinifera (Grape)
          Length = 738

 Score = 34.7 bits (76), Expect = 2.1
 Identities = 23/88 (26%), Positives = 46/88 (52%), Gaps = 5/88 (5%)
 Frame = +1

Query: 298 DEVCVFRDIKPASRFHILTIPKRH-IEDVKSLTSADKELLNRMMSI----SRELLSKNNL 462
           D+V V  D+ P ++ H+L + +   ++ +  +     +LL  M ++    + + L ++ L
Sbjct: 559 DDVVVLNDLYPKAQRHLLVLARSEGLDCLADVGGEHLQLLRTMHAVGLKWAEKFLCEDEL 618

Query: 463 SIEDARFGYHWPPFRSVKHLHLHTIAPE 546
            +   R GYH  P  S++ LHLH I+ +
Sbjct: 619 LV--FRIGYHSAP--SMRQLHLHVISQD 642


>UniRef50_Q8F4J7 Cluster: HIT family hydrolase; n=4; Leptospira|Rep:
           HIT family hydrolase - Leptospira interrogans
          Length = 176

 Score = 34.3 bits (75), Expect = 2.7
 Identities = 31/136 (22%), Positives = 53/136 (38%), Gaps = 5/136 (3%)
 Frame = +1

Query: 172 EPENQLFVXXXXXXXXXXXXXXXCIFCNIANKLEGTEILY--EDDEVCVFRDIKPASRFH 345
           EP   LF                CI C I  K      L   E +   V  ++ P +  H
Sbjct: 14  EPRKNLFSIHKLDYARGKRPDVDCILCGICRKDPEVPNLTVAETNFTIVSVNLYPYNPGH 73

Query: 346 ILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLSIEDARFGYHWPPFR--SVKH 519
           ++  PKRHI   + LT  +   ++   ++    + K   +++    GY+       S+ H
Sbjct: 74  LIVFPKRHILSYEELTKEEAMEIHE-GTVKAISILKKLWNVQGFNLGYNLGKNSGGSIPH 132

Query: 520 LHLHTIAP-ESEMGFI 564
           +H H +    +E GF+
Sbjct: 133 IHEHIVPRFPNEAGFL 148


>UniRef50_Q5GT45 Cluster: HIT family hydrolase; n=4;
           Rickettsiales|Rep: HIT family hydrolase - Wolbachia sp.
           subsp. Brugia malayi (strain TRS)
          Length = 122

 Score = 34.3 bits (75), Expect = 2.7
 Identities = 25/87 (28%), Positives = 39/87 (44%), Gaps = 3/87 (3%)
 Frame = +1

Query: 286 LYEDDEVCVFRDIKPASRFHILTIPK-RHIEDVKSLTSADKELLNRMMSISRELLSKNNL 462
           +YED++V  F D  P +  HIL +PK ++I     +  A  E +       RE+  K NL
Sbjct: 25  VYEDEDVLAFYDKYPDAPVHILVVPKSQYISYDDFIFKASAEEIVGFFKTVREITYKYNL 84

Query: 463 SIEDARFGYHWPP--FRSVKHLHLHTI 537
                R   +      + V H H+H +
Sbjct: 85  EKTGYRLVTNCGENGEQVVPHFHMHIL 111


>UniRef50_Q03WU6 Cluster: Diadenosine tetraphosphate (Ap4A)
           hydrolase related HIT family hydrolase; n=1; Leuconostoc
           mesenteroides subsp. mesenteroides ATCC 8293|Rep:
           Diadenosine tetraphosphate (Ap4A) hydrolase related HIT
           family hydrolase - Leuconostoc mesenteroides subsp.
           mesenteroides (strain ATCC 8293 /NCDO 523)
          Length = 140

 Score = 34.3 bits (75), Expect = 2.7
 Identities = 15/59 (25%), Positives = 35/59 (59%), Gaps = 1/59 (1%)
 Frame = +1

Query: 286 LYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSL-TSADKELLNRMMSISRELLSKNN 459
           +YED++V  F DI   +  H L +PK++++++        K++L ++  I+R + + ++
Sbjct: 17  VYEDEDVLAFLDISQVTPGHTLVVPKKNVDNIFDYDDETAKKVLLKLPVIARAIKASDD 75


>UniRef50_O76463 Cluster: Nitrilase and fragile histidine triad
           fusion protein NitFhit [Includes:
           Bis(5'-adenosyl)-triphosphatase (EC 3.6.1.29)
           (Diadenosine 5',5'''-P1,P3-triphosphate hydrolase)
           (Dinucleosidetriphosphatase) (AP3A hydrolase) (AP3Aase);
           Nitrilase homolog (EC 3.5.-.-)]; n=4; Bilateria|Rep:
           Nitrilase and fragile histidine triad fusion protein
           NitFhit [Includes: Bis(5'-adenosyl)-triphosphatase (EC
           3.6.1.29) (Diadenosine 5',5'''-P1,P3-triphosphate
           hydrolase) (Dinucleosidetriphosphatase) (AP3A hydrolase)
           (AP3Aase); Nitrilase homolog (EC 3.5.-.-)] -
           Caenorhabditis elegans
          Length = 440

 Score = 34.3 bits (75), Expect = 2.7
 Identities = 29/111 (26%), Positives = 49/111 (44%), Gaps = 1/111 (0%)
 Frame = +1

Query: 283 ILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSK-NN 459
           I Y      VF ++KP +  H+L  PKR +  +  LT A+   L  +    + +L K +N
Sbjct: 311 IFYSTPHSFVFVNLKPVTDGHVLVSPKRVVPRLTDLTDAETADLFIVAKKVQAMLEKHHN 370

Query: 460 LSIEDARFGYHWPPFRSVKHLHLHTIAPESEMGFIGRVIFKKNSYWFVSPE 612
           ++             ++V H+H+H I P     F    I++K +     PE
Sbjct: 371 VTSTTICVQDGKDAGQTVPHVHIH-ILPRRAGDFGDNEIYQKLASHDKEPE 420


>UniRef50_Q1IUV2 Cluster: Galactose-1-phosphate uridylyltransferase;
           n=11; Bacteria|Rep: Galactose-1-phosphate
           uridylyltransferase - Acidobacteria bacterium (strain
           Ellin345)
          Length = 344

 Score = 33.9 bits (74), Expect = 3.6
 Identities = 24/103 (23%), Positives = 47/103 (45%), Gaps = 6/103 (5%)
 Frame = +1

Query: 241 CIFCNIANKLE--GTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELL 414
           C++C+I  +    G  I+ E+D         P   F    +PKRH    ++ +S   + L
Sbjct: 199 CVYCDIIRQETEAGVRIIAENDSFVTLAPYAPRFPFETWVMPKRHESAFENASSKTYQDL 258

Query: 415 NRMMSISRELLSKNNLSIEDARFG--YHWPPFR--SVKHLHLH 531
            R +   ++LL K++  +++  +    H  P +  ++ H H H
Sbjct: 259 ARAL---KQLLMKSDRVLDNPAYNLVIHSAPIQDPALDHFHWH 298


>UniRef50_Q9V2L0 Cluster: Hit histidine triad protein; n=6;
           Archaea|Rep: Hit histidine triad protein - Pyrococcus
           abyssi
          Length = 185

 Score = 33.9 bits (74), Expect = 3.6
 Identities = 18/63 (28%), Positives = 31/63 (49%), Gaps = 2/63 (3%)
 Frame = +1

Query: 241 CIFCNIANKLEGTE--ILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELL 414
           CIFC+   +    E  ILY      +  +  P +  H++  P RH+  ++ LT  ++E+L
Sbjct: 38  CIFCDFPKENRDRERLILYRGKHAFIIMNNYPYNPGHVMVAPYRHVASIEDLT--EEEML 95

Query: 415 NRM 423
             M
Sbjct: 96  EIM 98


>UniRef50_A3DN62 Cluster: Histidine triad (HIT) protein; n=1;
           Staphylothermus marinus F1|Rep: Histidine triad (HIT)
           protein - Staphylothermus marinus (strain ATCC 43588 /
           DSM 3639 / F1)
          Length = 160

 Score = 33.9 bits (74), Expect = 3.6
 Identities = 23/81 (28%), Positives = 40/81 (49%), Gaps = 5/81 (6%)
 Frame = +1

Query: 241 CIFCNIANKLEGTE-ILYEDDEVCVFRDIKPASRFHILTIPKRH---IEDVK-SLTSADK 405
           CIFC +  K +    I+Y      V  +  P +  H+L +P +H   IED++  + +   
Sbjct: 24  CIFCELPKKKDNEAYIVYRGKYSYVVLNAYPYNSGHLLIVPYKHTPSIEDLEPEILTEMI 83

Query: 406 ELLNRMMSISRELLSKNNLSI 468
           ELLNR +   R+  + +  +I
Sbjct: 84  ELLNRSIKALRKSFTPDGFNI 104


>UniRef50_Q83GK4 Cluster: Putative uncharacterized protein; n=3;
           Micrococcineae|Rep: Putative uncharacterized protein -
           Tropheryma whipplei (strain Twist) (Whipple's bacillus)
          Length = 178

 Score = 33.5 bits (73), Expect = 4.8
 Identities = 30/103 (29%), Positives = 42/103 (40%), Gaps = 4/103 (3%)
 Frame = +1

Query: 241 CIFCNIANKL-EGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLN 417
           C FC+   K  E   I+Y  D   V  ++ P +  H L  P RHI     L S+D+ L  
Sbjct: 39  CPFCSAYRKTDEEGLIVYRGDLSYVVMNLYPYNSGHTLVCPYRHIA-TYDLASSDEILEM 97

Query: 418 RMMSISRELLSKNNLSIEDARFGYHWPPFRS---VKHLHLHTI 537
            ++     L+SK  L  E    G +           HLH H +
Sbjct: 98  GLLLQKAILVSKRVLGCEGFNIGINQGRVAGAGIAGHLHQHIV 140


>UniRef50_Q74CH2 Cluster: HIT family protein; n=3;
           Desulfuromonadales|Rep: HIT family protein - Geobacter
           sulfurreducens
          Length = 162

 Score = 33.5 bits (73), Expect = 4.8
 Identities = 30/117 (25%), Positives = 49/117 (41%), Gaps = 6/117 (5%)
 Frame = +1

Query: 241 CIFCNIANKLEGTE--ILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELL 414
           CIFC    +    E  IL+      V  +  P +  H++  P RH  D+ SL+ A+   L
Sbjct: 21  CIFCPGNGQASDRERLILHRTPLSLVMLNRYPYTNGHLMVAPLRHTADMDSLSDAEMLDL 80

Query: 415 NRMMSISRELLSKNNLSIEDARFGYHWPPFRSV---KHLHLHTIAP-ESEMGFIGRV 573
            R + + R +L ++  S      G +           HLH+H +     +  F+G V
Sbjct: 81  FRTVRLCRSIL-RDAASPNGYNIGINLGKAAGAGVDDHLHIHVVPRWNGDTNFMGVV 136


>UniRef50_A4BW57 Cluster: HIT family protein; n=14;
           Bacteroidetes|Rep: HIT family protein - Polaribacter
           irgensii 23-P
          Length = 131

 Score = 33.5 bits (73), Expect = 4.8
 Identities = 25/91 (27%), Positives = 43/91 (47%)
 Frame = +1

Query: 292 EDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNLSIE 471
           E+D    F DI P ++ H L +PK  +E+ K +    ++  ++++  S  +      +I 
Sbjct: 19  ENDNFIAFLDINPNAKGHALVVPK--VEENK-IFGLSRDAYHQLLDFSYTVAKSLEKAIS 75

Query: 472 DARFGYHWPPFRSVKHLHLHTIAPESEMGFI 564
             R G        V H+H+H I P +EM  I
Sbjct: 76  CKRVGMSIIGL-EVPHVHVHLI-PLNEMADI 104


>UniRef50_A2TZ69 Cluster: Putative cell-cycle regulation histidine
           triad protein; n=1; Polaribacter dokdonensis MED152|Rep:
           Putative cell-cycle regulation histidine triad protein -
           Polaribacter dokdonensis MED152
          Length = 121

 Score = 33.5 bits (73), Expect = 4.8
 Identities = 23/94 (24%), Positives = 46/94 (48%), Gaps = 2/94 (2%)
 Frame = +1

Query: 262 NKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRE 441
           N++    I++ ++   + +D  P S  H+L I K   +D   L+  +KE L +M+  +++
Sbjct: 5   NQIPKERIIFNNELFFIIKDKFPVSPGHLLIISKGIKKDFFELSLEEKEKLPKMIDKAKQ 64

Query: 442 LLSKNNLSIEDARFGYHW--PPFRSVKHLHLHTI 537
           L+ K   + +    G +      ++V H H H I
Sbjct: 65  LI-KQEYNPDGYNIGMNCGDSAGQTVFHFHCHII 97


>UniRef50_Q23921 Cluster: Protein pkiA; n=4; Dictyostelium
           discoideum|Rep: Protein pkiA - Dictyostelium discoideum
           (Slime mold)
          Length = 172

 Score = 33.5 bits (73), Expect = 4.8
 Identities = 23/86 (26%), Positives = 37/86 (43%), Gaps = 5/86 (5%)
 Frame = +1

Query: 289 YEDDEVCV-FRDIKPASRFHILTIPKRHIEDVKSLTSAD----KELLNRMMSISRELLSK 453
           + DDE C+   DI P +  H+L IPK  +  +  + + D    KE +  +MS    + S 
Sbjct: 83  FYDDEYCIAIEDINPQAPVHLLVIPKLAVGGLSDVANVDLEKYKESMGHIMSKIHHIASL 142

Query: 454 NNLSIEDARFGYHWPPFRSVKHLHLH 531
                            +SV+ LH+H
Sbjct: 143 KGADSYRLVINEGVLGQQSVRWLHIH 168


>UniRef50_Q6AQ03 Cluster: Putative uncharacterized protein; n=1;
           Desulfotalea psychrophila|Rep: Putative uncharacterized
           protein - Desulfotalea psychrophila
          Length = 169

 Score = 33.1 bits (72), Expect = 6.3
 Identities = 20/66 (30%), Positives = 33/66 (50%), Gaps = 4/66 (6%)
 Frame = +1

Query: 283 ILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKE----LLNRMMSISRELLS 450
           +LY D EV V  +  P +  H+L  P RHI  +  L+  +      ++ R  +I ++L S
Sbjct: 39  LLYRDSEVIVLLNRFPYANGHLLVAPIRHIACLTELSDGESYALMLMVKRSAAIIKQLFS 98

Query: 451 KNNLSI 468
              L+I
Sbjct: 99  PAGLNI 104


>UniRef50_A5UUJ2 Cluster: Putative uncharacterized protein
           precursor; n=4; Chloroflexaceae|Rep: Putative
           uncharacterized protein precursor - Roseiflexus sp. RS-1
          Length = 113

 Score = 33.1 bits (72), Expect = 6.3
 Identities = 15/48 (31%), Positives = 27/48 (56%)
 Frame = +1

Query: 319 DIKPASRFHILTIPKRHIEDVKSLTSADKELLNRMMSISRELLSKNNL 462
           +I+P     ILT+PK H +    +T   +  L +  S+ REL+ +++L
Sbjct: 56  EIEPGDTLEILTVPKTHGQTNGEITYPSRIRLTKASSLRRELVRRSSL 103


>UniRef50_A0LI77 Cluster: Type III restriction enzyme, res subunit;
           n=2; Deltaproteobacteria|Rep: Type III restriction
           enzyme, res subunit - Syntrophobacter fumaroxidans
           (strain DSM 10017 / MPOB)
          Length = 1077

 Score = 33.1 bits (72), Expect = 6.3
 Identities = 27/100 (27%), Positives = 42/100 (42%), Gaps = 1/100 (1%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELLNR 420
           C FC+     +   + YE   V    D  P +  H L +PKRH+      T  ++E L  
Sbjct: 6   CPFCSP----DDHRVFYEGKLVFALWDGFPVAPGHALLVPKRHVATWFDATPEEREELLA 61

Query: 421 MMSISRE-LLSKNNLSIEDARFGYHWPPFRSVKHLHLHTI 537
              + R+ +LS    +  +          ++V HLHLH I
Sbjct: 62  ATEVVRDHILSHFEPAGFNLGINIGTAAGQTVFHLHLHVI 101


>UniRef50_A7I5E0 Cluster: Histidine triad (HIT) protein; n=1;
           Candidatus Methanoregula boonei 6A8|Rep: Histidine triad
           (HIT) protein - Methanoregula boonei (strain 6A8)
          Length = 149

 Score = 33.1 bits (72), Expect = 6.3
 Identities = 21/73 (28%), Positives = 39/73 (53%), Gaps = 1/73 (1%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEILYEDDEVCVFR-DIKPASRFHILTIPKRHIEDVKSLTSADKELLN 417
           C FCN   +    EI+  +D +C  R D  PAS+ H+L +P RH     S+T  ++  + 
Sbjct: 6   CPFCNPLAE----EIVARND-LCYARWDRFPASKGHLLVLPFRHTPYFFSMTKEERREMI 60

Query: 418 RMMSISRELLSKN 456
            ++   ++++ +N
Sbjct: 61  ALIEACKQVIEEN 73


>UniRef50_Q6MP02 Cluster: Hit family hydrolase; n=1; Bdellovibrio
           bacteriovorus|Rep: Hit family hydrolase - Bdellovibrio
           bacteriovorus
          Length = 164

 Score = 32.7 bits (71), Expect = 8.3
 Identities = 17/73 (23%), Positives = 36/73 (49%), Gaps = 2/73 (2%)
 Frame = +1

Query: 241 CIFCNIANKLEGTEIL--YEDDEVCVFRDIKPASRFHILTIPKRHIEDVKSLTSADKELL 414
           C+FC  + +    E L  ++     V  +  P +  H+L +PKRH  D+  L+  +   L
Sbjct: 24  CVFCRASEEKVSFETLCVFKSKHSMVVLNKFPYNSGHLLVLPKRHCGDLLKLSDDEYHDL 83

Query: 415 NRMMSISRELLSK 453
             ++ ++ + L++
Sbjct: 84  QNVIRLTMQALNE 96


>UniRef50_Q560L7 Cluster: Putative uncharacterized protein; n=2;
           Filobasidiella neoformans|Rep: Putative uncharacterized
           protein - Cryptococcus neoformans (Filobasidiella
           neoformans)
          Length = 367

 Score = 32.7 bits (71), Expect = 8.3
 Identities = 18/80 (22%), Positives = 41/80 (51%), Gaps = 5/80 (6%)
 Frame = +1

Query: 262 NKLEGTEILYEDDEVCVFRDIKPASRF-----HILTIPKRHIEDVKSLTSADKELLNRMM 426
           N++ G EI+Y D ++ V++  +   R      HI+ +   H++ V    ++D  LL+ ++
Sbjct: 76  NRVGGREIVYHDKDITVYK-AEGKERLCQGGRHIIIVVNEHLQSVYEFGASDIPLLSHIL 134

Query: 427 SISRELLSKNNLSIEDARFG 486
             + ++L+    + +D   G
Sbjct: 135 DTAAQILNSVAAAGDDLESG 154


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 606,407,015
Number of Sequences: 1657284
Number of extensions: 11278137
Number of successful extensions: 21800
Number of sequences better than 10.0: 238
Number of HSP's better than 10.0 without gapping: 21268
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 21757
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 51652897375
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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