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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= bmte10e11
         (681 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_UPI0000D55663 Cluster: PREDICTED: similar to CG6906-PA;...   147   2e-34
UniRef50_Q17F02 Cluster: Carbonic anhydrase, putative; n=2; Culi...   140   2e-32
UniRef50_UPI00015B587C Cluster: PREDICTED: similar to carbonic a...    95   1e-18
UniRef50_Q17AD2 Cluster: Carbonic anhydrase; n=2; Culicidae|Rep:...    92   1e-17
UniRef50_A3FFY2 Cluster: Glycosyl-phosphatidylinositol-linked ca...    90   5e-17
UniRef50_Q1HR09 Cluster: Carbonic anhydrase; n=3; Coelomata|Rep:...    89   1e-16
UniRef50_Q9VTU8 Cluster: CG6906-PA; n=2; Sophophora|Rep: CG6906-...    87   3e-16
UniRef50_Q4V4S9 Cluster: IP11239p; n=3; Sophophora|Rep: IP11239p...    87   3e-16
UniRef50_UPI00015B6360 Cluster: PREDICTED: similar to carbonic a...    87   5e-16
UniRef50_UPI0000DB7CE2 Cluster: PREDICTED: similar to CG6074-PA;...    81   2e-14
UniRef50_Q17N62 Cluster: Carbonic anhydrase II, putative; n=1; A...    76   7e-13
UniRef50_UPI0000DB7BA3 Cluster: PREDICTED: similar to Carbonic a...    76   9e-13
UniRef50_UPI00003C0BC4 Cluster: PREDICTED: similar to CG12309-PA...    76   9e-13
UniRef50_A7S2D8 Cluster: Predicted protein; n=1; Nematostella ve...    75   1e-12
UniRef50_Q6NWD3 Cluster: LOC407683 protein; n=4; Danio rerio|Rep...    75   2e-12
UniRef50_Q10462 Cluster: Putative carbonic anhydrase 5 precursor...    75   2e-12
UniRef50_Q28XJ3 Cluster: GA11547-PA; n=1; Drosophila pseudoobscu...    74   3e-12
UniRef50_Q2HZX8 Cluster: Carbonic anhydrase FCA-b; n=2; Fungia s...    73   6e-12
UniRef50_UPI000155CD20 Cluster: PREDICTED: hypothetical protein;...    72   1e-11
UniRef50_UPI00015B6049 Cluster: PREDICTED: similar to carbonic a...    71   2e-11
UniRef50_UPI00015B4702 Cluster: PREDICTED: similar to IP11339p; ...    71   2e-11
UniRef50_UPI0000EB41E1 Cluster: Carbonic anhydrase 5A, mitochond...    71   2e-11
UniRef50_Q7QBY3 Cluster: ENSANGP00000001278; n=1; Anopheles gamb...    71   3e-11
UniRef50_UPI0000D55660 Cluster: PREDICTED: similar to CG12309-PA...    71   3e-11
UniRef50_Q9W3C8 Cluster: CG11284-PA; n=7; Diptera|Rep: CG11284-P...    70   5e-11
UniRef50_Q8MS78 Cluster: LP05719p; n=1; Drosophila melanogaster|...    70   6e-11
UniRef50_Q9VB76 Cluster: CG6074-PA; n=6; Diptera|Rep: CG6074-PA ...    69   8e-11
UniRef50_Q4RVK0 Cluster: Chromosome 15 SCAF14992, whole genome s...    69   1e-10
UniRef50_A7SKA8 Cluster: Predicted protein; n=2; Nematostella ve...    69   1e-10
UniRef50_UPI0000F2CC28 Cluster: PREDICTED: similar to Car15 prot...    68   2e-10
UniRef50_P43166 Cluster: Carbonic anhydrase 7; n=15; Euteleostom...    68   2e-10
UniRef50_UPI00015B54D1 Cluster: PREDICTED: similar to carbonic a...    67   3e-10
UniRef50_UPI00005A4B0A Cluster: PREDICTED: similar to carbonic a...    67   4e-10
UniRef50_UPI0000660174 Cluster: Carbonic anhydrase 5A, mitochond...    65   2e-09
UniRef50_Q16RN8 Cluster: Carbonic anhydrase II, putative; n=1; A...    65   2e-09
UniRef50_UPI0000E48172 Cluster: PREDICTED: hypothetical protein;...    64   3e-09
UniRef50_UPI000024BB46 Cluster: PREDICTED: similar to carbonic a...    64   3e-09
UniRef50_Q0IHN2 Cluster: Car15 protein; n=3; Xenopus tropicalis|...    64   3e-09
UniRef50_Q4VPE4 Cluster: Carbonic anhydrase precursor; n=13; Tri...    64   3e-09
UniRef50_Q9Y2D0 Cluster: Carbonic anhydrase 5B, mitochondrial pr...    64   3e-09
UniRef50_Q8N1Q1 Cluster: Carbonic anhydrase 13; n=133; Vertebrat...    64   3e-09
UniRef50_UPI0000E46DA6 Cluster: PREDICTED: similar to Carbonic a...    64   4e-09
UniRef50_Q16W62 Cluster: Carbonic anhydrase II, putative; n=3; A...    64   4e-09
UniRef50_Q8V4Y0 Cluster: Cell surface-binding protein; n=32; Ort...    64   4e-09
UniRef50_UPI0000DB7206 Cluster: PREDICTED: similar to CG3940-PA;...    63   5e-09
UniRef50_Q9V9Y7 Cluster: CG18672-PA; n=1; Drosophila melanogaste...    63   5e-09
UniRef50_Q0QBU7 Cluster: Carbonic anhydrase; n=4; Echinoida|Rep:...    62   1e-08
UniRef50_P35219 Cluster: Carbonic anhydrase-related protein; n=2...    62   1e-08
UniRef50_Q99N23 Cluster: Carbonic anhydrase 15 precursor; n=4; E...    62   1e-08
UniRef50_Q27504 Cluster: Putative carbonic anhydrase 3; n=2; Cae...    61   3e-08
UniRef50_Q4FCT9 Cluster: Carbonic anhydrase 4; n=1; Squalus acan...    60   4e-08
UniRef50_Q9XZG6 Cluster: Carbonic anhydrase; n=1; Anthopleura el...    60   4e-08
UniRef50_UPI0000D55661 Cluster: PREDICTED: similar to CG11284-PA...    60   5e-08
UniRef50_UPI0000ECA9F1 Cluster: UPI0000ECA9F1 related cluster; n...    60   5e-08
UniRef50_Q9V396 Cluster: CG7820-PA; n=9; Endopterygota|Rep: CG78...    60   5e-08
UniRef50_Q9W2Q2 Cluster: CG9235-PA; n=3; Sophophora|Rep: CG9235-...    60   6e-08
UniRef50_Q9VH26 Cluster: CG3940-PA; n=3; Sophophora|Rep: CG3940-...    60   6e-08
UniRef50_Q8IMV4 Cluster: CG10899-PA, isoform A; n=5; Sophophora|...    60   6e-08
UniRef50_Q6WLH6 Cluster: Carbonic anhydrase; n=2; Anopheles gamb...    60   6e-08
UniRef50_Q16RN9 Cluster: Carbonic anhydrase II, putative; n=1; A...    59   9e-08
UniRef50_UPI0000E48EBE Cluster: PREDICTED: hypothetical protein;...    59   1e-07
UniRef50_UPI0000E21B4D Cluster: PREDICTED: hypothetical protein ...    58   1e-07
UniRef50_UPI000044959A Cluster: PREDICTED: similar to carbonic a...    58   1e-07
UniRef50_P23280 Cluster: Carbonic anhydrase 6 precursor; n=11; E...    58   1e-07
UniRef50_Q1LY76 Cluster: Novel protein; n=4; Clupeocephala|Rep: ...    58   2e-07
UniRef50_UPI0000E47C8E Cluster: PREDICTED: similar to CG7820-PA;...    56   6e-07
UniRef50_Q4RRY2 Cluster: Chromosome 7 SCAF15001, whole genome sh...    56   6e-07
UniRef50_Q9W3P7 Cluster: CG1402-PA; n=3; Endopterygota|Rep: CG14...    56   6e-07
UniRef50_Q29QI5 Cluster: IP04174p; n=4; Endopterygota|Rep: IP041...    56   6e-07
UniRef50_UPI00015B6431 Cluster: PREDICTED: similar to CG1402-PA;...    56   8e-07
UniRef50_Q4SLF0 Cluster: Chromosome 7 SCAF14557, whole genome sh...    56   8e-07
UniRef50_UPI0000D575C0 Cluster: PREDICTED: similar to CG5379-PA;...    56   1e-06
UniRef50_Q4S1J8 Cluster: Chromosome 6 SCAF14768, whole genome sh...    56   1e-06
UniRef50_Q32LW3 Cluster: LOC553246 protein; n=7; Clupeocephala|R...    56   1e-06
UniRef50_Q9Q8L7 Cluster: M83L; n=2; Leporipoxvirus|Rep: M83L - M...    55   1e-06
UniRef50_Q5DFH8 Cluster: SJCHGC06606 protein; n=1; Schistosoma j...    55   1e-06
UniRef50_A3FFY1 Cluster: Cytoplasmic carbonic anydrase; n=1; Cal...    55   1e-06
UniRef50_Q16790 Cluster: Carbonic anhydrase 9 precursor; n=21; T...    55   2e-06
UniRef50_Q21614 Cluster: Putative uncharacterized protein cah-4;...    54   4e-06
UniRef50_A7SHT0 Cluster: Predicted protein; n=1; Nematostella ve...    54   4e-06
UniRef50_Q4SLZ9 Cluster: Chromosome 13 SCAF14555, whole genome s...    53   6e-06
UniRef50_Q9W316 Cluster: CG32698-PA; n=5; Endopterygota|Rep: CG3...    53   6e-06
UniRef50_O02637 Cluster: Carbonic anhydrase protein 6; n=3; Rhab...    52   1e-05
UniRef50_Q8MPH8 Cluster: Carbonic anhydrase; n=1; Riftia pachypt...    52   1e-05
UniRef50_P18761 Cluster: Carbonic anhydrase 6 precursor; n=11; E...    52   1e-05
UniRef50_Q98936 Cluster: Receptor-type tyrosine-protein phosphat...    52   2e-05
UniRef50_A1L3H6 Cluster: LOC100037010 protein; n=4; Xenopus|Rep:...    51   2e-05
UniRef50_Q6NZJ2 Cluster: Car10 protein; n=16; Euteleostomi|Rep: ...    51   2e-05
UniRef50_UPI0000F2BCDF Cluster: PREDICTED: similar to carbonic a...    51   3e-05
UniRef50_UPI0000586D72 Cluster: PREDICTED: similar to Chain A, C...    50   4e-05
UniRef50_UPI00004D5334 Cluster: Carbonic anhydrase 4 precursor (...    50   5e-05
UniRef50_Q4SWK8 Cluster: Chromosome undetermined SCAF13612, whol...    50   5e-05
UniRef50_Q7LZP1 Cluster: Carbonate dehydratase; n=1; Galeocerdo ...    50   7e-05
UniRef50_Q1ECZ8 Cluster: Zgc:158584; n=10; Danio rerio|Rep: Zgc:...    49   9e-05
UniRef50_Q18932 Cluster: Putative carbonic anhydrase-like protei...    49   9e-05
UniRef50_Q7SYW3 Cluster: MGC64443 protein; n=3; Xenopus|Rep: MGC...    49   1e-04
UniRef50_Q4SZW1 Cluster: Chromosome undetermined SCAF11462, whol...    49   1e-04
UniRef50_P23470 Cluster: Receptor-type tyrosine-protein phosphat...    49   1e-04
UniRef50_UPI0000F2BDC6 Cluster: PREDICTED: similar to Carbonic a...    48   2e-04
UniRef50_UPI000065D5A1 Cluster: Carbonic anhydrase 6 precursor (...    48   2e-04
UniRef50_Q20781 Cluster: Putative carbonic anhydrase-like protei...    48   3e-04
UniRef50_UPI000065EB91 Cluster: Homolog of Homo sapiens "Splice ...    47   5e-04
UniRef50_Q9ULX7 Cluster: Carbonic anhydrase 14 precursor; n=17; ...    46   6e-04
UniRef50_A7S762 Cluster: Predicted protein; n=1; Nematostella ve...    46   9e-04
UniRef50_A6YCJ0 Cluster: Astrosclerin-2; n=3; Astrosclera willey...    46   9e-04
UniRef50_Q3B7E6 Cluster: Zgc:123188; n=2; Danio rerio|Rep: Zgc:1...    46   0.001
UniRef50_A3KNU9 Cluster: Si:ch211-258f14.6 protein; n=5; Danio r...    46   0.001
UniRef50_UPI0000E1EBDB Cluster: PREDICTED: carbonic anhydrase XI...    45   0.001
UniRef50_UPI000069EFAD Cluster: UPI000069EFAD related cluster; n...    45   0.002
UniRef50_UPI0000ECAF42 Cluster: Carbonic anhydrase 12 precursor ...    45   0.002
UniRef50_Q4T8T1 Cluster: Chromosome undetermined SCAF7729, whole...    45   0.002
UniRef50_A6QR78 Cluster: Carbonic anhydrase 1; n=2; Nematostella...    44   0.003
UniRef50_A6QR75 Cluster: Carbonic anhydrase 1; n=1; Amphimedon q...    44   0.003
UniRef50_UPI0001555A70 Cluster: PREDICTED: hypothetical protein;...    44   0.005
UniRef50_UPI0000F21610 Cluster: PREDICTED: similar to protein ty...    44   0.005
UniRef50_UPI00005A2CD6 Cluster: PREDICTED: similar to Receptor-t...    43   0.006
UniRef50_UPI00006C1B11 Cluster: PREDICTED: similar to carbonic a...    43   0.008
UniRef50_O43570 Cluster: Carbonic anhydrase 12 precursor; n=37; ...    43   0.008
UniRef50_UPI00015A4051 Cluster: hypothetical protein LOC406461; ...    42   0.011
UniRef50_Q7SZR2 Cluster: Zgc:77106; n=7; Clupeocephala|Rep: Zgc:...    42   0.011
UniRef50_Q28ZR2 Cluster: GA13586-PA; n=1; Drosophila pseudoobscu...    42   0.018
UniRef50_Q62656 Cluster: Receptor-type tyrosine-protein phosphat...    42   0.018
UniRef50_UPI0000E249D6 Cluster: PREDICTED: carbonic anhydrase IV...    41   0.024
UniRef50_P23471-2 Cluster: Isoform Short of P23471 ; n=6; Tetrap...    40   0.042
UniRef50_Q4SE53 Cluster: Chromosome undetermined SCAF14625, whol...    40   0.042
UniRef50_P23471 Cluster: Receptor-type tyrosine-protein phosphat...    40   0.042
UniRef50_O75493 Cluster: Carbonic anhydrase-related protein 11 p...    40   0.042
UniRef50_UPI0000ECD15B Cluster: Carbonic anhydrase 1 (EC 4.2.1.1...    40   0.074
UniRef50_A5FDD4 Cluster: Putative uncharacterized protein precur...    39   0.098
UniRef50_P22748 Cluster: Carbonic anhydrase 4 precursor; n=15; E...    39   0.098
UniRef50_O93587 Cluster: Carbonic anhydrase; n=5; Percomorpha|Re...    38   0.17 
UniRef50_A6QR76 Cluster: Carbonic anhydrase 2; n=1; Amphimedon q...    36   0.69 
UniRef50_UPI0000EB222F Cluster: UPI0000EB222F related cluster; n...    36   1.2  
UniRef50_A6QR77 Cluster: Carbonic anhydrase 3; n=1; Amphimedon q...    36   1.2  
UniRef50_UPI0000ECC003 Cluster: UPI0000ECC003 related cluster; n...    35   1.6  
UniRef50_Q3U3I1 Cluster: NOD-derived CD11c +ve dendritic cells c...    35   1.6  
UniRef50_A0E1X6 Cluster: Chromosome undetermined scaffold_74, wh...    34   2.8  
UniRef50_Q6FQK5 Cluster: Candida glabrata strain CBS138 chromoso...    34   3.7  
UniRef50_Q1DMJ1 Cluster: Predicted protein; n=1; Coccidioides im...    33   6.4  
UniRef50_Q5BY01 Cluster: SJCHGC07514 protein; n=1; Schistosoma j...    33   8.5  
UniRef50_Q7S1M6 Cluster: Putative uncharacterized protein NCU092...    33   8.5  

>UniRef50_UPI0000D55663 Cluster: PREDICTED: similar to CG6906-PA;
           n=1; Tribolium castaneum|Rep: PREDICTED: similar to
           CG6906-PA - Tribolium castaneum
          Length = 266

 Score =  147 bits (357), Expect = 2e-34
 Identities = 60/136 (44%), Positives = 95/136 (69%)
 Frame = +1

Query: 214 QWIYYWSDFEGHLPTPINVSITGSIPYTCPELKWYNFDVFPHKVKLSNTGYTVLIGAKWK 393
           ++I   +D E    +PI+++I+ +     P L W++ D+ P K+K++N+GYT+++ AKW 
Sbjct: 11  RYIQTLTDTETVYESPIDINISKTKEIQVPPLTWHHLDLPPKKMKVTNSGYTLILSAKWH 70

Query: 394 AERPYLEGGPFQDKHIFSQIHFHWGADMMEGSDHTVDDRRYPGEMQVTFFRSEYMTQEEA 573
            ERPY+ GGP    ++FSQ+HFHWG +  EGS+HT+D  RYP EM V FF++ Y+TQE A
Sbjct: 71  QERPYISGGPLLGNYVFSQLHFHWGKNDGEGSEHTIDGVRYPIEMHVVFFKANYLTQESA 130

Query: 574 LRHPDGVVMICYLIKV 621
           L+  DG+V++ Y+ K+
Sbjct: 131 LKEKDGIVVLVYMFKL 146


>UniRef50_Q17F02 Cluster: Carbonic anhydrase, putative; n=2;
           Culicidae|Rep: Carbonic anhydrase, putative - Aedes
           aegypti (Yellowfever mosquito)
          Length = 328

 Score =  140 bits (340), Expect = 2e-32
 Identities = 61/131 (46%), Positives = 87/131 (66%), Gaps = 1/131 (0%)
 Frame = +1

Query: 241 EGHLPTPINVSITGSIPYTCPELKWYNFDVFPHKVKLSNTGYTVLIGAKW-KAERPYLEG 417
           E  LP+PI+++I  +   T P+L W+ +D  P K+KL+NTG TV++ AKW ++  PYLEG
Sbjct: 39  EAWLPSPIDININCAEKLTLPDLLWHGYDTLPSKIKLTNTGETVILSAKWPESAIPYLEG 98

Query: 418 GPFQDKHIFSQIHFHWGADMMEGSDHTVDDRRYPGEMQVTFFRSEYMTQEEALRHPDGVV 597
           GP + +++FSQ+HFHWG   ++GS HT+D    P EM V  F + Y TQEEAL+H  GVV
Sbjct: 99  GPLEGRYVFSQLHFHWGNTAVDGSAHTIDKAHLPLEMHVIHFNTNYETQEEALQHVGGVV 158

Query: 598 MICYLIKVVRS 630
            + Y   +  S
Sbjct: 159 SLVYFFNLKSS 169


>UniRef50_UPI00015B587C Cluster: PREDICTED: similar to carbonic
           anhydrase; n=1; Nasonia vitripennis|Rep: PREDICTED:
           similar to carbonic anhydrase - Nasonia vitripennis
          Length = 308

 Score = 95.1 bits (226), Expect = 1e-18
 Identities = 44/138 (31%), Positives = 75/138 (54%), Gaps = 3/138 (2%)
 Frame = +1

Query: 217 WIYYWSDFEGHLPTPINVSITG--SIPYTCPELKWYNFDVFPHKVKLSNTGYTVLIGAKW 390
           W+  +    G   +PIN+ +     +    P L  Y +D  P K+ ++N G++V +   W
Sbjct: 58  WLADFPICSGPRQSPINIELQDVKMMESKRPPLGRYGYDTRPKKMTITNNGHSVQLSGVW 117

Query: 391 KA-ERPYLEGGPFQDKHIFSQIHFHWGADMMEGSDHTVDDRRYPGEMQVTFFRSEYMTQE 567
            A + P + GGP    +  +Q+HFHWGAD   GS+HTV +  +P EM +  ++  Y    
Sbjct: 118 PARDTPTVYGGPLTGLYELAQVHFHWGADNDAGSEHTVANHSFPLEMHMVHWKKAYQNIS 177

Query: 568 EALRHPDGVVMICYLIKV 621
           EA++H DG+ ++ YL+ +
Sbjct: 178 EAIKHDDGIAVLGYLLSL 195


>UniRef50_Q17AD2 Cluster: Carbonic anhydrase; n=2; Culicidae|Rep:
           Carbonic anhydrase - Aedes aegypti (Yellowfever
           mosquito)
          Length = 347

 Score = 91.9 bits (218), Expect = 1e-17
 Identities = 43/135 (31%), Positives = 71/135 (52%)
 Frame = +1

Query: 217 WIYYWSDFEGHLPTPINVSITGSIPYTCPELKWYNFDVFPHKVKLSNTGYTVLIGAKWKA 396
           W   ++   G   +PIN++         P L +  FDV P +  L+N G+TV +  K   
Sbjct: 36  WGEQYNSCTGKHQSPININSLDVKKVNLPPLIFDGFDVPPQQTNLTNNGHTVAVTMK-SD 94

Query: 397 ERPYLEGGPFQDKHIFSQIHFHWGADMMEGSDHTVDDRRYPGEMQVTFFRSEYMTQEEAL 576
             P + GGP    + +SQ+HFHWG +   GS+  +D+  +P E+ V FF+ +Y   + AL
Sbjct: 95  HIPTISGGPLNGTYQYSQLHFHWGDNDTFGSEDMIDNHIFPMELHVVFFKQDYRNAKTAL 154

Query: 577 RHPDGVVMICYLIKV 621
            H DG+ ++ +  +V
Sbjct: 155 EHSDGLTVLAFFYEV 169


>UniRef50_A3FFY2 Cluster: Glycosyl-phosphatidylinositol-linked
           carbonic anhydrase; n=1; Callinectes sapidus|Rep:
           Glycosyl-phosphatidylinositol-linked carbonic anhydrase
           - Callinectes sapidus (Blue crab)
          Length = 308

 Score = 89.8 bits (213), Expect = 5e-17
 Identities = 42/145 (28%), Positives = 78/145 (53%)
 Frame = +1

Query: 202 YGTLQWIYYWSDFEGHLPTPINVSITGSIPYTCPELKWYNFDVFPHKVKLSNTGYTVLIG 381
           +G L W   +    G+  +PIN+            L   N++  P ++++ N G++  + 
Sbjct: 32  HGPLHWGSMFQSCAGNRQSPINIETLNVKQEYWKPLLLKNYEKAPSRMRVKNNGHSAQVE 91

Query: 382 AKWKAERPYLEGGPFQDKHIFSQIHFHWGADMMEGSDHTVDDRRYPGEMQVTFFRSEYMT 561
               A  P + GG  + ++IF+Q HFHWGAD   GS+HT+D  RYP E+ +  ++  Y T
Sbjct: 92  ID-AAVAPRVTGGGLKGEYIFAQFHFHWGADSTLGSEHTIDGVRYPMELHMVHYKGSYGT 150

Query: 562 QEEALRHPDGVVMICYLIKVVRSES 636
             EA++  DG+ ++  +++V  +++
Sbjct: 151 LGEAVKRRDGLAVLGVMLEVSSNDN 175


>UniRef50_Q1HR09 Cluster: Carbonic anhydrase; n=3; Coelomata|Rep:
           Carbonic anhydrase - Aedes aegypti (Yellowfever
           mosquito)
          Length = 379

 Score = 88.6 bits (210), Expect = 1e-16
 Identities = 36/91 (39%), Positives = 55/91 (60%), Gaps = 1/91 (1%)
 Frame = +1

Query: 334 PHKVKLSNTGYTVLIGAKWK-AERPYLEGGPFQDKHIFSQIHFHWGADMMEGSDHTVDDR 510
           P  ++L N G++      W+  ERPY+ GGP + K+ F Q HFHWGA+   GS+H +D  
Sbjct: 174 PQSIRLQNDGHSAKFTYVWRNGERPYIRGGPLKTKYYFEQFHFHWGANSSVGSEHVLDFH 233

Query: 511 RYPGEMQVTFFRSEYMTQEEALRHPDGVVMI 603
           RYP E+ + F+ + Y + EEA    DG+ ++
Sbjct: 234 RYPMELHLLFYNALYSSFEEARSEVDGLAVV 264


>UniRef50_Q9VTU8 Cluster: CG6906-PA; n=2; Sophophora|Rep: CG6906-PA
           - Drosophila melanogaster (Fruit fly)
          Length = 335

 Score = 87.4 bits (207), Expect = 3e-16
 Identities = 42/145 (28%), Positives = 75/145 (51%), Gaps = 5/145 (3%)
 Frame = +1

Query: 202 YGTLQWIYYWSDFEGHLPTPINVSITGSIPYTCPELKWYNFDVFPHKVKLSNTGYTVLIG 381
           +G   W   ++   G   +PIN+    ++    P+L+++NF V P  ++++N G+TVL+ 
Sbjct: 34  HGPEHWSEDYARCSGKHQSPINIDQVSAVEKKFPKLEFFNFKVVPDNLQMTNNGHTVLVK 93

Query: 382 AKWKAER-PYLEGGPFQDK----HIFSQIHFHWGADMMEGSDHTVDDRRYPGEMQVTFFR 546
             +  +  P + GGP  +K    + F Q HFHWG +   GS+  +++R YP E+ V    
Sbjct: 94  MSYNEDEIPSVRGGPLAEKTPLGYQFEQFHFHWGENDTIGSEDLINNRAYPAELHVVLRN 153

Query: 547 SEYMTQEEALRHPDGVVMICYLIKV 621
            EY     AL    G+ ++ +  +V
Sbjct: 154 LEYPDFASALDKDHGIAVMAFFFQV 178


>UniRef50_Q4V4S9 Cluster: IP11239p; n=3; Sophophora|Rep: IP11239p -
           Drosophila melanogaster (Fruit fly)
          Length = 303

 Score = 87.4 bits (207), Expect = 3e-16
 Identities = 46/142 (32%), Positives = 78/142 (54%), Gaps = 3/142 (2%)
 Frame = +1

Query: 214 QWIYYWSDFEGHLPTPINVSITGSIPYTCPELKWYNFD-VFPHKVKLSNTGYTV--LIGA 384
           +W   + +  G   +PI +S   +IP   P L +  +D  F   V + N+G+TV   +  
Sbjct: 35  RWPEKYPNCGGSEQSPIAISRRKAIPLNLPPLIFALYDEFFDELVTIRNSGHTVEFKVPT 94

Query: 385 KWKAERPYLEGGPFQDKHIFSQIHFHWGADMMEGSDHTVDDRRYPGEMQVTFFRSEYMTQ 564
                +PY+ GG  +D +    +HFHWG+   +GS+H ++ RR+  EM +    ++Y+  
Sbjct: 95  TIYGVKPYVTGGLLRDCYDAEAVHFHWGSPESKGSEHLLNGRRFDLEMHIVHRNTKYLNL 154

Query: 565 EEALRHPDGVVMICYLIKVVRS 630
           EEA+++ DGV ++  L KVVRS
Sbjct: 155 EEAVKYSDGVTVLAVLFKVVRS 176


>UniRef50_UPI00015B6360 Cluster: PREDICTED: similar to carbonic
           anhydrase; n=1; Nasonia vitripennis|Rep: PREDICTED:
           similar to carbonic anhydrase - Nasonia vitripennis
          Length = 350

 Score = 86.6 bits (205), Expect = 5e-16
 Identities = 39/139 (28%), Positives = 71/139 (51%)
 Frame = +1

Query: 202 YGTLQWIYYWSDFEGHLPTPINVSITGSIPYTCPELKWYNFDVFPHKVKLSNTGYTVLIG 381
           +G   W   +    G   +PIN+          P L +   D+ P KV L N G+T L+ 
Sbjct: 49  HGPAHWAEDYDTCFGKHQSPINILEHDVRDTNLPPLLFSGLDL-PRKVYLVNNGHTALLH 107

Query: 382 AKWKAERPYLEGGPFQDKHIFSQIHFHWGADMMEGSDHTVDDRRYPGEMQVTFFRSEYMT 561
           A   +E+ Y+ GGP    ++F Q+HFHWG +  EGS+  +++  +  E+   F++ +Y +
Sbjct: 108 ASKDSEKAYMSGGPLNGTYVFEQLHFHWGENDREGSEDLINNHSFAMELHAVFYKDDYGS 167

Query: 562 QEEALRHPDGVVMICYLIK 618
              A+ + DG+ ++ +  +
Sbjct: 168 MNGAVAYRDGLAVLAFFFE 186


>UniRef50_UPI0000DB7CE2 Cluster: PREDICTED: similar to CG6074-PA;
           n=1; Apis mellifera|Rep: PREDICTED: similar to CG6074-PA
           - Apis mellifera
          Length = 296

 Score = 81.0 bits (191), Expect = 2e-14
 Identities = 44/134 (32%), Positives = 70/134 (52%), Gaps = 5/134 (3%)
 Frame = +1

Query: 217 WIYYWSDFEGHLPTPINVSITGSIPYTCPELKWYNF-DVFPHKVKLSNTGYTVLIGAKWK 393
           WI  +    G L +PI++S   SIP   P L+   + D  P+ + L N G++V+I    +
Sbjct: 25  WIQNFKLCGGKLQSPIHISSFKSIPLPLPALETIGYHDFLPNPLYLKNNGHSVVININNR 84

Query: 394 AER--PYLEGGPFQ--DKHIFSQIHFHWGADMMEGSDHTVDDRRYPGEMQVTFFRSEYMT 561
            E+  PY+ GG      ++    +HFHWGA   +GS+H ++  RYP EM +      Y  
Sbjct: 85  FEKRLPYIFGGSLNVNQEYEIDHLHFHWGAKNNKGSEHILNGVRYPMEMHIVHKNKIYSN 144

Query: 562 QEEALRHPDGVVMI 603
              AL + DG+V++
Sbjct: 145 LSNALNYKDGLVVL 158


>UniRef50_Q17N62 Cluster: Carbonic anhydrase II, putative; n=1;
           Aedes aegypti|Rep: Carbonic anhydrase II, putative -
           Aedes aegypti (Yellowfever mosquito)
          Length = 273

 Score = 76.2 bits (179), Expect = 7e-13
 Identities = 48/147 (32%), Positives = 76/147 (51%), Gaps = 3/147 (2%)
 Frame = +1

Query: 205 GTLQW--IYYWSDFEGHLPTPINVSITGSIPYTCPELKWYNFDVFPHKVKLSNTGYTVLI 378
           G  QW  I  + D +   P  ++  +  ++    P L+  N    P KV++ N G+TV+ 
Sbjct: 29  GVEQWGLISKFCDGDRQSPIDLDSKLVQTVAEGKP-LELTNVCENPTKVRVHNNGHTVIF 87

Query: 379 GAKWKAERPY-LEGGPFQDKHIFSQIHFHWGADMMEGSDHTVDDRRYPGEMQVTFFRSEY 555
              + A +   L+GGP +    FS +HFHWGA+      HTVD  R+P EM + F+  EY
Sbjct: 88  SLTYPASKGVILQGGPLEGTFKFSSLHFHWGAE------HTVDMERFPLEMHMVFYNQEY 141

Query: 556 MTQEEALRHPDGVVMICYLIKVVRSES 636
            +  +A   P+G+ ++ Y   V RSE+
Sbjct: 142 GSVHKAQFQPNGLAVLGYFF-VERSEA 167


>UniRef50_UPI0000DB7BA3 Cluster: PREDICTED: similar to Carbonic
           anhydrase 2 CG6906-PA, partial; n=1; Apis mellifera|Rep:
           PREDICTED: similar to Carbonic anhydrase 2 CG6906-PA,
           partial - Apis mellifera
          Length = 164

 Score = 75.8 bits (178), Expect = 9e-13
 Identities = 36/136 (26%), Positives = 73/136 (53%)
 Frame = +1

Query: 205 GTLQWIYYWSDFEGHLPTPINVSITGSIPYTCPELKWYNFDVFPHKVKLSNTGYTVLIGA 384
           G   W   +    G   +PI++        T P+L++ + +   H   + N G+TV+I +
Sbjct: 29  GPSHWGDEYKQCIGKFQSPIDIEEKDVTNMTFPKLQFSDTEN-SHVAYMINNGHTVMIRS 87

Query: 385 KWKAERPYLEGGPFQDKHIFSQIHFHWGADMMEGSDHTVDDRRYPGEMQVTFFRSEYMTQ 564
            +  + P + GGP  + ++F Q+HFHWG +   GS+  +++R +  E+   F++ +Y + 
Sbjct: 88  -FDPDLPTISGGPINNTYVFQQLHFHWGQNDNLGSEDLINNRSFSMELHAVFWKKQYGSY 146

Query: 565 EEALRHPDGVVMICYL 612
           ++A  + DG+ ++ YL
Sbjct: 147 DKATEYSDGLTVLGYL 162


>UniRef50_UPI00003C0BC4 Cluster: PREDICTED: similar to CG12309-PA;
           n=2; Apocrita|Rep: PREDICTED: similar to CG12309-PA -
           Apis mellifera
          Length = 293

 Score = 75.8 bits (178), Expect = 9e-13
 Identities = 39/148 (26%), Positives = 74/148 (50%), Gaps = 4/148 (2%)
 Frame = +1

Query: 205 GTLQWIYYWSDFEGHLPTPINVSITGSIPYTCPE-LKWYNFDVFPHKVKLSNTGYTVLIG 381
           G   W   + D  G   +PINV+   ++     E L+W  +D  P  + ++N    V++ 
Sbjct: 44  GPHMWKLLYPDSNGGNQSPINVTTQLAVVVQPSEPLRWSGYDKGPLSMTITNNENNVVLN 103

Query: 382 AKWK-AERPYLEGGPFQDKHIFSQIHFHWGADMMEGSDHTVDDRRYPGEMQVTFFRSEYM 558
             W    RPY++GG     +    + FHWG    EGS+HT D  R+P E+QV   +  + 
Sbjct: 104 TMWSNTTRPYIQGGCLTSVYDLCSMVFHWGHSNEEGSEHTFDYVRFPMELQVWHIKRGFN 163

Query: 559 TQEEAL--RHPDGVVMICYLIKVVRSES 636
           +  +A+  +  DG++++ +  ++  +++
Sbjct: 164 SLLDAITAKENDGILIVSFFFQITNADN 191


>UniRef50_A7S2D8 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 234

 Score = 75.4 bits (177), Expect = 1e-12
 Identities = 44/126 (34%), Positives = 63/126 (50%), Gaps = 3/126 (2%)
 Frame = +1

Query: 244 GHLPTPIN-VSITGSIPYTCPELKWYNFDVFPHKVKLSNTGYTVLIGAKWKAE--RPYLE 414
           G   +PI+ VS       T P +K  ++D F  K KL+NTG++V    +  A    P + 
Sbjct: 15  GKRQSPIDIVSNETKFDSTIPPVK-VHYDPFT-KGKLTNTGHSVSFSGESDASVPTPDIT 72

Query: 415 GGPFQDKHIFSQIHFHWGADMMEGSDHTVDDRRYPGEMQVTFFRSEYMTQEEALRHPDGV 594
            GP   K+ F+Q HFHWG D  EGS+H VD + YP EM +  + S+      +    D  
Sbjct: 73  SGPLSHKYKFAQFHFHWGKDEKEGSEHRVDGKMYPSEMHIVHYNSDLYKDAASAMSSDNK 132

Query: 595 VMICYL 612
             +C L
Sbjct: 133 DGLCVL 138


>UniRef50_Q6NWD3 Cluster: LOC407683 protein; n=4; Danio rerio|Rep:
           LOC407683 protein - Danio rerio (Zebrafish) (Brachydanio
           rerio)
          Length = 309

 Score = 74.9 bits (176), Expect = 2e-12
 Identities = 43/141 (30%), Positives = 71/141 (50%), Gaps = 2/141 (1%)
 Frame = +1

Query: 205 GTLQWIYYWSDFEGHLPTPINVSITGSIPYTCPELKWYNFDVFPHKVKLS--NTGYTVLI 378
           G  QW   ++   G   +PIN+ IT  + Y  P+L  + FD       +S  N G++   
Sbjct: 35  GPSQWKINYTSCGGQKQSPINI-ITSKVKYD-PKLTSFIFDGHEDAFNMSVENHGHSAHF 92

Query: 379 GAKWKAERPYLEGGPFQDKHIFSQIHFHWGADMMEGSDHTVDDRRYPGEMQVTFFRSEYM 558
                A   +L GG  + K+   Q H HWG +  +GS+H+VD  RYP E+ + +   EY+
Sbjct: 93  TLPPSA---HLSGGGLKGKYKAVQFHLHWGENGSQGSEHSVDGERYPMELHIVYIGEEYI 149

Query: 559 TQEEALRHPDGVVMICYLIKV 621
              +AL++  GV ++ +  +V
Sbjct: 150 NLTKALQNSTGVAVLAFFFEV 170


>UniRef50_Q10462 Cluster: Putative carbonic anhydrase 5 precursor;
           n=1; Caenorhabditis elegans|Rep: Putative carbonic
           anhydrase 5 precursor - Caenorhabditis elegans
          Length = 310

 Score = 74.5 bits (175), Expect = 2e-12
 Identities = 34/101 (33%), Positives = 60/101 (59%), Gaps = 2/101 (1%)
 Frame = +1

Query: 307 LKWYNFDVFPHKVKLSNTGYTVLIGA--KWKAERPYLEGGPFQDKHIFSQIHFHWGADMM 480
           + + N+D+   K++LSNTG T+  G    W+ ++P ++GG  + ++  +Q H HWG +  
Sbjct: 67  MHFLNYDM-DGKIELSNTGRTLFAGGFESWQHKQPMIQGGGLKHRYKLAQFHLHWGQNDA 125

Query: 481 EGSDHTVDDRRYPGEMQVTFFRSEYMTQEEALRHPDGVVMI 603
            GS+H +    YP E+ +   R E +T +EAL  PDG+ ++
Sbjct: 126 VGSEHAMGSLHYPAELHLVHVR-EGLTLKEALSRPDGLAVV 165


>UniRef50_Q28XJ3 Cluster: GA11547-PA; n=1; Drosophila
           pseudoobscura|Rep: GA11547-PA - Drosophila pseudoobscura
           (Fruit fly)
          Length = 580

 Score = 74.1 bits (174), Expect = 3e-12
 Identities = 34/104 (32%), Positives = 57/104 (54%), Gaps = 1/104 (0%)
 Frame = +1

Query: 256 TPINVSITGSIPYTCPEL-KWYNFDVFPHKVKLSNTGYTVLIGAKWKAERPYLEGGPFQD 432
           +PIN+      P    EL  W ++D  P  +++ NTG+T+++ A++    P + G     
Sbjct: 102 SPINIDDRQLSPMAIRELLNWNHYDELPASIQVENTGHTLILRAQFHGNTPTISGADLLA 161

Query: 433 KHIFSQIHFHWGADMMEGSDHTVDDRRYPGEMQVTFFRSEYMTQ 564
            + F ++ FHWG    EGS+HT + R++P EMQV    S  M++
Sbjct: 162 SYTFVEVRFHWGWCNSEGSEHTFNHRKFPMEMQVMHRASSGMSR 205


>UniRef50_Q2HZX8 Cluster: Carbonic anhydrase FCA-b; n=2; Fungia
           scutaria|Rep: Carbonic anhydrase FCA-b - Fungia scutaria
          Length = 225

 Score = 72.9 bits (171), Expect = 6e-12
 Identities = 36/142 (25%), Positives = 78/142 (54%), Gaps = 2/142 (1%)
 Frame = +1

Query: 217 WIYYWSDFEGHLPTPINVSITGSIPYTCPELKWYNFDVFPHKV-KLSNTGYTVLIGAKWK 393
           W +++ D  GH  +P+N+    ++          N++  P+ + KL N G++  I A + 
Sbjct: 38  WAHHYPDCAGHKQSPVNIVPKQTVFDAGLADLTINYE--PNVLAKLENNGHS--IQASFL 93

Query: 394 AERPYLEGGPFQDKHIFSQIHFHWGADMMEGSDHTVDDRRYPGEMQVTFFRSE-YMTQEE 570
             +  + GG    +   +Q+HFHWG++ + GS+H ++ R+YP E+ +  + +E Y     
Sbjct: 94  TGKSNISGGGLPSRFQTAQLHFHWGSENLRGSEHQINGRKYPMEIHIVHYNAEKYPNAST 153

Query: 571 ALRHPDGVVMICYLIKVVRSES 636
           A++ PDG+ ++  L+++  +++
Sbjct: 154 AMKKPDGLAVLGILVELQANDN 175


>UniRef50_UPI000155CD20 Cluster: PREDICTED: hypothetical protein;
           n=2; Mammalia|Rep: PREDICTED: hypothetical protein -
           Ornithorhynchus anatinus
          Length = 436

 Score = 72.1 bits (169), Expect = 1e-11
 Identities = 31/92 (33%), Positives = 54/92 (58%)
 Frame = +1

Query: 346 KLSNTGYTVLIGAKWKAERPYLEGGPFQDKHIFSQIHFHWGADMMEGSDHTVDDRRYPGE 525
           ++ N G+   +  +  A+R  L+GGP    +   Q HFHWG+   +GS+HTVD  +Y  E
Sbjct: 234 RVVNNGHAFNVEFEDSADRSVLKGGPLSGTYRLIQFHFHWGSCDDKGSEHTVDGVKYAAE 293

Query: 526 MQVTFFRSEYMTQEEALRHPDGVVMICYLIKV 621
           + +  + ++Y    EA++HPDG+ ++   +KV
Sbjct: 294 LHLVHWNTKYGKFGEAVKHPDGLAVLGVFLKV 325


>UniRef50_UPI00015B6049 Cluster: PREDICTED: similar to carbonic
           anhydrase 6; n=1; Nasonia vitripennis|Rep: PREDICTED:
           similar to carbonic anhydrase 6 - Nasonia vitripennis
          Length = 280

 Score = 71.3 bits (167), Expect = 2e-11
 Identities = 29/106 (27%), Positives = 56/106 (52%), Gaps = 1/106 (0%)
 Frame = +1

Query: 307 LKWYNFDVFPHKVKLSNTGYTVLIGAKWKAERPYLEGGPFQDK-HIFSQIHFHWGADMME 483
           L++ N+   P +  ++N G+T+ +   W+A  P + G  F D+ + FS  H HWG     
Sbjct: 65  LQFLNYTARPRQFSVNNEGHTIQLTGAWQANAPSITGSVFSDEVYTFSNAHVHWGTQDTN 124

Query: 484 GSDHTVDDRRYPGEMQVTFFRSEYMTQEEALRHPDGVVMICYLIKV 621
           G++H+++ +++  E+ +     +Y    EA    DG+ +I  L +V
Sbjct: 125 GTEHSINGQKFACELHLVHINRKYRNLTEATNRSDGIAVIGVLFQV 170


>UniRef50_UPI00015B4702 Cluster: PREDICTED: similar to IP11339p;
           n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
           IP11339p - Nasonia vitripennis
          Length = 301

 Score = 71.3 bits (167), Expect = 2e-11
 Identities = 31/108 (28%), Positives = 60/108 (55%), Gaps = 1/108 (0%)
 Frame = +1

Query: 301 PELKWYNFDVFPHKVKLSNTGYTVLIGAKWKAERPYLEGGPFQ-DKHIFSQIHFHWGADM 477
           P +++ N+ + P  V + N G+T  +  KW    PY+ G     +K+ F  +H HWG   
Sbjct: 62  PPIEFMNYHLKPIVVNILNDGHTANLTGKWSNGIPYVTGDLVNGEKYNFLDLHAHWGKGQ 121

Query: 478 MEGSDHTVDDRRYPGEMQVTFFRSEYMTQEEALRHPDGVVMICYLIKV 621
            +G++H+++ +R+  E+ +    S+Y    +AL + DGV+++  L +V
Sbjct: 122 DDGTEHSINGQRFSAELHLVHVNSKYKDLAQALNYVDGVLVVGLLFEV 169


>UniRef50_UPI0000EB41E1 Cluster: Carbonic anhydrase 5A,
           mitochondrial precursor (EC 4.2.1.1) (Carbonic anhydrase
           VA) (Carbonate dehydratase VA) (CA-VA).; n=1; Canis
           lupus familiaris|Rep: Carbonic anhydrase 5A,
           mitochondrial precursor (EC 4.2.1.1) (Carbonic anhydrase
           VA) (Carbonate dehydratase VA) (CA-VA). - Canis
           familiaris
          Length = 227

 Score = 71.3 bits (167), Expect = 2e-11
 Identities = 34/93 (36%), Positives = 51/93 (54%), Gaps = 1/93 (1%)
 Frame = +1

Query: 355 NTGYTVLIGAKWKAERPYLEGGPFQDKHIFSQIHFHWGADMMEGSDHTVDDRRYPGEMQV 534
           NTGY   +      E   + GGP ++ +   Q HFHWGA    GS+HTVDDR YP E+ +
Sbjct: 48  NTGYFFQVEFDDSTEGSGISGGPLENHYRLKQFHFHWGAANAWGSEHTVDDRAYPAELHL 107

Query: 535 TFFRS-EYMTQEEALRHPDGVVMICYLIKVVRS 630
             + S +Y   +EA+   +GV +I   ++  R+
Sbjct: 108 VHWNSVKYQNYKEAIMGENGVAVIGVFLQGARA 140


>UniRef50_Q7QBY3 Cluster: ENSANGP00000001278; n=1; Anopheles gambiae
           str. PEST|Rep: ENSANGP00000001278 - Anopheles gambiae
           str. PEST
          Length = 278

 Score = 70.9 bits (166), Expect = 3e-11
 Identities = 28/79 (35%), Positives = 45/79 (56%)
 Frame = +1

Query: 400 RPYLEGGPFQDKHIFSQIHFHWGADMMEGSDHTVDDRRYPGEMQVTFFRSEYMTQEEALR 579
           RP + GGP +  + F Q+HFHWG +  EGS+H ++  R+P E+ + F+   Y +  EA  
Sbjct: 96  RPMMRGGPLKTAYFFEQMHFHWGPNNSEGSEHRINGERFPLEVHLVFYNGLYQSLAEAAG 155

Query: 580 HPDGVVMICYLIKVVRSES 636
             DG+ ++ +   VV   S
Sbjct: 156 EVDGLAVVGFFYDVVPGSS 174


>UniRef50_UPI0000D55660 Cluster: PREDICTED: similar to CG12309-PA;
           n=1; Tribolium castaneum|Rep: PREDICTED: similar to
           CG12309-PA - Tribolium castaneum
          Length = 296

 Score = 70.5 bits (165), Expect = 3e-11
 Identities = 46/145 (31%), Positives = 72/145 (49%), Gaps = 6/145 (4%)
 Frame = +1

Query: 205 GTLQWIYYWSDFEGHLPTPINV-SITGSIPYT---CPELKWYNFDVFPHKVKLSNTGYTV 372
           G   W Y +    G   +PIN+ S+   +  T    P      + + P ++KL N GYTV
Sbjct: 46  GPNTWKYRFQ-IRGENQSPINILSVCAVVVPTETIAPLDFTSEYHITPQEMKLLNDGYTV 104

Query: 373 LIGAKWK-AERPYLEGGPFQDKHIFSQIHFHWGADMMEGSDHTVDDRRYPGEMQVTFFRS 549
           +I + W    +P + GGP  D++    I F WG +  EGS+H +D RRY  E+QVT+ + 
Sbjct: 105 VIYSTWSNGRKPTVCGGPLCDEYKLFSIRFRWGPNDEEGSEHMIDMRRYAMELQVTYNKC 164

Query: 550 EYMTQEEALR-HPDGVVMICYLIKV 621
                + A       V++I Y+ +V
Sbjct: 165 SCKCTDMAKSIKTCAVIIISYMFEV 189


>UniRef50_Q9W3C8 Cluster: CG11284-PA; n=7; Diptera|Rep: CG11284-PA -
           Drosophila melanogaster (Fruit fly)
          Length = 250

 Score = 70.1 bits (164), Expect = 5e-11
 Identities = 30/103 (29%), Positives = 54/103 (52%), Gaps = 1/103 (0%)
 Frame = +1

Query: 346 KLSNTGYTVLIGAKWKAERPYLEGGPF-QDKHIFSQIHFHWGADMMEGSDHTVDDRRYPG 522
           ++ NTG + ++    + ++PY+ GG   QD ++F Q+HFHW      G +HT++  +Y  
Sbjct: 36  RVQNTGTSAMVTFSKRKQQPYIIGGALEQDMYVFEQLHFHWSDCDESGCEHTLEGMKYSM 95

Query: 523 EMQVTFFRSEYMTQEEALRHPDGVVMICYLIKVVRSES*QTFK 651
           E     + S+Y    EA   PDG+ ++ + I+    +    FK
Sbjct: 96  EAHAVHYNSKYKDFTEAKNKPDGLAVVAFFIQACGEKDCPEFK 138


>UniRef50_Q8MS78 Cluster: LP05719p; n=1; Drosophila
           melanogaster|Rep: LP05719p - Drosophila melanogaster
           (Fruit fly)
          Length = 527

 Score = 69.7 bits (163), Expect = 6e-11
 Identities = 28/76 (36%), Positives = 45/76 (59%)
 Frame = +1

Query: 307 LKWYNFDVFPHKVKLSNTGYTVLIGAKWKAERPYLEGGPFQDKHIFSQIHFHWGADMMEG 486
           L W ++D  P  + L NTG T+++ A++    P + G      + F ++ FHWG    EG
Sbjct: 131 LSWNHYDDLPASITLENTGQTLILRAQFHGNAPTISGADLLASYTFLELRFHWGWCNSEG 190

Query: 487 SDHTVDDRRYPGEMQV 534
           S+HT++ R++P EMQV
Sbjct: 191 SEHTINHRKFPLEMQV 206


>UniRef50_Q9VB76 Cluster: CG6074-PA; n=6; Diptera|Rep: CG6074-PA -
           Drosophila melanogaster (Fruit fly)
          Length = 311

 Score = 69.3 bits (162), Expect = 8e-11
 Identities = 39/148 (26%), Positives = 66/148 (44%), Gaps = 8/148 (5%)
 Frame = +1

Query: 214 QWIYYWSDFEGHLPTPINVSITGSIPYTCPELKWYNF-DVFPHKVKLSNTGYTVLIGA-K 387
           +W  +     G   +PI ++ + +     P +    + ++ P+ +K+ N G+TV I   K
Sbjct: 34  RWARHHGHCAGKTQSPIAITTSRTTAIHMPAVDMIGYHNLLPYPLKMINNGHTVSITIPK 93

Query: 388 WKAER------PYLEGGPFQDKHIFSQIHFHWGADMMEGSDHTVDDRRYPGEMQVTFFRS 549
                      PY+ G     +     +HFHWG     GS+H ++D RY  EM +     
Sbjct: 94  VNVTEVGEDFLPYIRGAKLPGEFEVEGLHFHWGDKNNRGSEHVINDIRYTMEMHIVHRNK 153

Query: 550 EYMTQEEALRHPDGVVMICYLIKVVRSE 633
           +Y T  EAL HPDG  ++ +   +   E
Sbjct: 154 KYATIGEALNHPDGAAVLGFFFNLDEDE 181


>UniRef50_Q4RVK0 Cluster: Chromosome 15 SCAF14992, whole genome
           shotgun sequence; n=3; Tetraodontidae|Rep: Chromosome 15
           SCAF14992, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 323

 Score = 68.5 bits (160), Expect = 1e-10
 Identities = 39/128 (30%), Positives = 67/128 (52%), Gaps = 1/128 (0%)
 Frame = +1

Query: 241 EGHLPTPINVSITG-SIPYTCPELKWYNFDVFPHKVKLSNTGYTVLIGAKWKAERPYLEG 417
           +G   +PIN+      +        +  FD      ++ NTG+TV      K +   + G
Sbjct: 48  DGERQSPINIEKKSVEVDENLESFTFTKFDDKHAIEQIVNTGHTVK--CTLKQDTVEISG 105

Query: 418 GPFQDKHIFSQIHFHWGADMMEGSDHTVDDRRYPGEMQVTFFRSEYMTQEEALRHPDGVV 597
           G  +  +   Q HFHWG+ + +GS+HTVD  RYP EM +   R + +T +EA++ PDG+ 
Sbjct: 106 GSLEHVYSTLQFHFHWGS-VTDGSEHTVDSHRYPMEMHIVSKRKD-LTLDEAVQTPDGLA 163

Query: 598 MICYLIKV 621
           ++ + I++
Sbjct: 164 VLGFFIEM 171


>UniRef50_A7SKA8 Cluster: Predicted protein; n=2; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 250

 Score = 68.5 bits (160), Expect = 1e-10
 Identities = 39/143 (27%), Positives = 70/143 (48%), Gaps = 4/143 (2%)
 Frame = +1

Query: 205 GTLQWIYYWSDFEGHLPTPINVSITGSIPY--TCPELKWYNFDVFP--HKVKLSNTGYTV 372
           G  +W   +S   G   +PI++ IT S+ +  +  EL++ NFD  P   K+ L N G+  
Sbjct: 1   GPSKWSSSFSQCNGSSQSPIDI-ITSSVAFDQSLGELQFVNFDTIPTGSKISLKNNGHAF 59

Query: 373 LIGAKWKAERPYLEGGPFQDKHIFSQIHFHWGADMMEGSDHTVDDRRYPGEMQVTFFRSE 552
            +     A    + GG     +   Q H HWG+   +GS+H +D + + G + +  + ++
Sbjct: 60  QVNML-SAGTFTVSGGGLGATYSTVQFHLHWGSKNEQGSEHLIDGKAFAGAIHIVSYNTK 118

Query: 553 YMTQEEALRHPDGVVMICYLIKV 621
           Y     A+   DG+ ++  L+KV
Sbjct: 119 YPNISAAVDKSDGLAVVGILLKV 141


>UniRef50_UPI0000F2CC28 Cluster: PREDICTED: similar to Car15
           protein; n=2; Amniota|Rep: PREDICTED: similar to Car15
           protein - Monodelphis domestica
          Length = 437

 Score = 67.7 bits (158), Expect = 2e-10
 Identities = 32/99 (32%), Positives = 52/99 (52%), Gaps = 2/99 (2%)
 Frame = +1

Query: 346 KLSNTGYTVLIGAKWKAERPYL--EGGPFQDKHIFSQIHFHWGADMMEGSDHTVDDRRYP 519
           +L N G+TV +  +    +  L  +GG     +   Q+HFHWG+    GS+HT+D +R P
Sbjct: 200 RLLNNGHTVELSLEGAGGQGQLCIQGGGLSHSYCALQLHFHWGSPTSNGSEHTLDGQRQP 259

Query: 520 GEMQVTFFRSEYMTQEEALRHPDGVVMICYLIKVVRSES 636
            EM V    + Y +  EA  HP G+ ++ +  KV   ++
Sbjct: 260 MEMHVVHMNTLYQSLGEARGHPRGLAVLAFFFKVQNKDN 298


>UniRef50_P43166 Cluster: Carbonic anhydrase 7; n=15;
           Euteleostomi|Rep: Carbonic anhydrase 7 - Homo sapiens
           (Human)
          Length = 264

 Score = 67.7 bits (158), Expect = 2e-10
 Identities = 38/135 (28%), Positives = 66/135 (48%), Gaps = 2/135 (1%)
 Frame = +1

Query: 205 GTLQWIYYWSDFEGHLPTPINVSITGSIPYTCPELKWYNFDVFP-HKVKLSNTGYTVLIG 381
           G   W   +   +G   +PIN+ I+    Y+ P L+           + ++N G++V + 
Sbjct: 14  GPSHWHKLYPIAQGDRQSPINI-ISSQAVYS-PSLQPLELSYEACMSLSITNNGHSVQVD 71

Query: 382 AKWKAERPYLEGGPFQDKHIFSQIHFHWGADMMEGSDHTVDDRRYPGEMQVTFFRS-EYM 558
                +R  + GGP +  +   Q HFHWG     GS+HTVD + +P E+ +  + + +Y 
Sbjct: 72  FNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSELHLVHWNAKKYS 131

Query: 559 TQEEALRHPDGVVMI 603
           T  EA   PDG+ ++
Sbjct: 132 TFGEAASAPDGLAVV 146


>UniRef50_UPI00015B54D1 Cluster: PREDICTED: similar to carbonic
           anhydrase; n=1; Nasonia vitripennis|Rep: PREDICTED:
           similar to carbonic anhydrase - Nasonia vitripennis
          Length = 306

 Score = 67.3 bits (157), Expect = 3e-10
 Identities = 37/139 (26%), Positives = 63/139 (45%), Gaps = 6/139 (4%)
 Frame = +1

Query: 205 GTLQWIYYWSDFEGHLPTPINVSITGSIPYTCPELKWYNF-DVFPHKVKLSNTGYTVLIG 381
           G   W+  +    G   +P+ ++ + S+    P L+   + D     +   N G+TV + 
Sbjct: 30  GQHYWVKEYPQCAGFWQSPVIIAASRSVTLPLPALEMIGYHDFLSLPLIFKNNGHTVSVR 89

Query: 382 AKWKAER---PYLEGGPFQDKHIFS--QIHFHWGADMMEGSDHTVDDRRYPGEMQVTFFR 546
            K +      PY+ G   ++   +     HFHWG     GS+H +   RYP EM +    
Sbjct: 90  VKHEFTHRRFPYIFGALLKENEEYELESFHFHWGLKNSRGSEHVLHGTRYPMEMHLIHRN 149

Query: 547 SEYMTQEEALRHPDGVVMI 603
           ++Y   E ALRH DG+ ++
Sbjct: 150 TKYPNLENALRHEDGLTVL 168


>UniRef50_UPI00005A4B0A Cluster: PREDICTED: similar to carbonic
           anhydrase 15; n=1; Canis lupus familiaris|Rep:
           PREDICTED: similar to carbonic anhydrase 15 - Canis
           familiaris
          Length = 305

 Score = 66.9 bits (156), Expect = 4e-10
 Identities = 45/146 (30%), Positives = 66/146 (45%), Gaps = 6/146 (4%)
 Frame = +1

Query: 196 PLYGTLQWIYYWSDFEGHLPTPINVSITGSIPYTCPELKWYNFDVF----PHKVKLSNTG 363
           P  G   W        G   +PIN+ +   +    P L  + F  +    P    L N G
Sbjct: 32  PKCGPTHWKEMAPACGGPAQSPINIDL--HLVQQDPALGPFIFQGYHSAPPGPWTLENDG 89

Query: 364 YTVLIGAKWKAE-RPYLEGGPFQ-DKHIFSQIHFHWGADMMEGSDHTVDDRRYPGEMQVT 537
           +TVL+      + R  + G       +   Q+HFHWG     GS+H+VD +RYP EM V 
Sbjct: 90  HTVLLRMDTDPQSRLEIRGAGLPLPAYRALQLHFHWGGPGRAGSEHSVDGQRYPMEMHVV 149

Query: 538 FFRSEYMTQEEALRHPDGVVMICYLI 615
              + Y + EEA  HPDG+ ++  L+
Sbjct: 150 HMNTRYQSIEEARSHPDGLAVLAVLL 175


>UniRef50_UPI0000660174 Cluster: Carbonic anhydrase 5A,
           mitochondrial precursor (EC 4.2.1.1) (Carbonic anhydrase
           VA) (Carbonate dehydratase VA) (CA-VA).; n=3;
           Clupeocephala|Rep: Carbonic anhydrase 5A, mitochondrial
           precursor (EC 4.2.1.1) (Carbonic anhydrase VA)
           (Carbonate dehydratase VA) (CA-VA). - Takifugu rubripes
          Length = 181

 Score = 64.9 bits (151), Expect = 2e-09
 Identities = 35/95 (36%), Positives = 51/95 (53%), Gaps = 1/95 (1%)
 Frame = +1

Query: 244 GHLPTPINVSITGSIPYTCPELKWYNFDVFPHKVK-LSNTGYTVLIGAKWKAERPYLEGG 420
           GH  +PI++ +  S+  +   LK    D  P   + + N GY+ L+     A++  L+GG
Sbjct: 59  GHCQSPIDIVVRKSVFDSA--LKPLATDYDPETCQQIWNNGYSFLVEYDDSADKSTLKGG 116

Query: 421 PFQDKHIFSQIHFHWGADMMEGSDHTVDDRRYPGE 525
           P QD+    Q HFHWG     GS+HTVD R +P E
Sbjct: 117 PLQDQFRLCQFHFHWGESNAWGSEHTVDRRLFPAE 151


>UniRef50_Q16RN8 Cluster: Carbonic anhydrase II, putative; n=1;
           Aedes aegypti|Rep: Carbonic anhydrase II, putative -
           Aedes aegypti (Yellowfever mosquito)
          Length = 284

 Score = 64.9 bits (151), Expect = 2e-09
 Identities = 38/139 (27%), Positives = 68/139 (48%), Gaps = 6/139 (4%)
 Frame = +1

Query: 205 GTLQWIYYWSDFEGHLPTPINVSITGSIP-YTCPELKWYNFDVFPHKVKLSNTGYTVLIG 381
           G  +W   + +  G + +PI +S   + P +    L+  N+ + P +V ++N G   +  
Sbjct: 31  GESEWGNMYPECNGTMQSPIPLSAMTARPGFETQPLEIANYQLDPTQVIVNNDGKLAIYR 90

Query: 382 AKWKA-ERPYLEGGPFQDKHIFSQIHFHWGADMMEGSDHTVDD----RRYPGEMQVTFFR 546
            ++   E   + GGP Q    F  +HFHWGA    GS+H +D     +R+  EM + FF 
Sbjct: 91  FEFPGGENVTIRGGPLQGIFQFDSLHFHWGAASDRGSEHVIDSMTGRKRFAMEMHLVFFN 150

Query: 547 SEYMTQEEALRHPDGVVMI 603
             Y + +EA    +G+ ++
Sbjct: 151 QIYGSFQEAAPSENGLAVL 169


>UniRef50_UPI0000E48172 Cluster: PREDICTED: hypothetical protein;
           n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
           hypothetical protein - Strongylocentrotus purpuratus
          Length = 303

 Score = 64.1 bits (149), Expect = 3e-09
 Identities = 35/144 (24%), Positives = 69/144 (47%), Gaps = 7/144 (4%)
 Frame = +1

Query: 226 YWSDFEGHL-----PTPINVSITGSIPYTCPELKWYNFDVFPHKVKLSNTGYTV-LIGAK 387
           +W D  G        +PIN+    +           ++D     V + N G+ + ++ + 
Sbjct: 40  FWKDIPGSFCGDSSQSPINIDTKKTSDIGLAPFNLQSYDT-TKPVTIENNGHALEVVLSN 98

Query: 388 WKAERPY-LEGGPFQDKHIFSQIHFHWGADMMEGSDHTVDDRRYPGEMQVTFFRSEYMTQ 564
              E  Y + GG         Q HFH+G++ M+GS+HTVD +RYP +M +  + + Y + 
Sbjct: 99  GAGEGQYDITGGGLNGTFRAVQFHFHFGSNDMKGSEHTVDGKRYPADMHIVHYDTAYGSV 158

Query: 565 EEALRHPDGVVMICYLIKVVRSES 636
            EA++   G+ ++ + ++V   ++
Sbjct: 159 NEAIKKKGGIAVLGFFLEVSEDDN 182


>UniRef50_UPI000024BB46 Cluster: PREDICTED: similar to carbonic
           anhydrase 9; n=2; Danio rerio|Rep: PREDICTED: similar to
           carbonic anhydrase 9 - Danio rerio
          Length = 384

 Score = 64.1 bits (149), Expect = 3e-09
 Identities = 36/132 (27%), Positives = 65/132 (49%), Gaps = 3/132 (2%)
 Frame = +1

Query: 217 WIYYWSDFEGHLPTPINVSITGSIPYT--CPELKWYNFDVF-PHKVKLSNTGYTVLIGAK 387
           W+  +    G   +PIN+  T  + +    P ++   +D+   H + L N G+T+ +   
Sbjct: 52  WLSAFEHCGGKSQSPINID-THKVLHEPRLPPIQLDGYDLTGSHSLTLLNNGHTLQLSLP 110

Query: 388 WKAERPYLEGGPFQDKHIFSQIHFHWGADMMEGSDHTVDDRRYPGEMQVTFFRSEYMTQE 567
                  +  G F   ++ +Q+HFHWG   + GS+HT+D+  YP E+ V  + S+Y    
Sbjct: 111 SSMR---IRRG-FDQVYVAAQLHFHWGTTEVPGSEHTIDNIHYPAEIHVVHYNSKYANLT 166

Query: 568 EALRHPDGVVMI 603
           EA    DG+ ++
Sbjct: 167 EAASKADGLAVL 178


>UniRef50_Q0IHN2 Cluster: Car15 protein; n=3; Xenopus
           tropicalis|Rep: Car15 protein - Xenopus tropicalis
           (Western clawed frog) (Silurana tropicalis)
          Length = 310

 Score = 64.1 bits (149), Expect = 3e-09
 Identities = 30/116 (25%), Positives = 61/116 (52%), Gaps = 4/116 (3%)
 Frame = +1

Query: 334 PHKVKLSNTGYTVLIGAKWKAERPY--LEGGPFQDKHIFSQIHFHWGADMMEGSDHTVDD 507
           P + KL N G++VL+    +  + +  + G    + +   Q HFHWG+   +GS+H +D 
Sbjct: 67  PGRWKLINDGHSVLLSLSGEVIQSHVNISGAGLPNTYRALQFHFHWGSSTRDGSEHLMDG 126

Query: 508 RRYPGEMQVTFFRSEYMTQEEALRHPDGVVMICYLIKV--VRSES*QTFKLGSRRI 669
           ++YP E+ +    ++Y +  EA + P G+ ++ +   V  + + S  T + G + +
Sbjct: 127 KQYPMELHIVHMNAKYQSITEAKKDPQGLAVLGFFFTVSEIDNPSYNTLEAGMKNV 182


>UniRef50_Q4VPE4 Cluster: Carbonic anhydrase precursor; n=13;
           Tridacna gigas|Rep: Carbonic anhydrase precursor -
           Tridacna gigas
          Length = 600

 Score = 64.1 bits (149), Expect = 3e-09
 Identities = 37/145 (25%), Positives = 72/145 (49%), Gaps = 6/145 (4%)
 Frame = +1

Query: 205 GTLQWIYYWSDFEGHLPTPINVSITGSIPYTCPELKWYNFDVFPHKV------KLSNTGY 366
           G   W    S   G+  +PI++   G + Y  P L  +N   +   +      +L+N G+
Sbjct: 30  GPAAWNNIASICNGNRQSPISIPY-GHVTYD-PSLTSFNLTGYDDTMTSSGPLQLTNNGH 87

Query: 367 TVLIGAKWKAERPYLEGGPFQDKHIFSQIHFHWGADMMEGSDHTVDDRRYPGEMQVTFFR 546
           TV++     A    + GG    ++  +Q+H+HWGAD   GS+H +D+R  P E+ +  ++
Sbjct: 88  TVVLNVN-TANATKMSGGGLDGEYYAAQLHYHWGADDSVGSEHAIDNRYSPLEVHLVHYK 146

Query: 547 SEYMTQEEALRHPDGVVMICYLIKV 621
           +   +    L+  DG+ ++ +L ++
Sbjct: 147 ASAGSVSAGLQSGDGLAVLGFLFEI 171



 Score = 60.9 bits (141), Expect = 3e-08
 Identities = 34/146 (23%), Positives = 68/146 (46%), Gaps = 7/146 (4%)
 Frame = +1

Query: 205 GTLQWIYYWSDFEGHLPTPINVSITGSIPYT-------CPELKWYNFDVFPHKVKLSNTG 363
           G   W  Y++   G   +PI++    S+             L++ N+D   + + + N G
Sbjct: 304 GVDSWSTYYATCSGKKQSPIDIPAVTSVKVAQFDSNKGLDTLEFINYDQTINGI-IKNNG 362

Query: 364 YTVLIGAKWKAERPYLEGGPFQDKHIFSQIHFHWGADMMEGSDHTVDDRRYPGEMQVTFF 543
           +T+ +      +  Y+  G    +   +Q HFHWG +  EGS+HT + R+YP E+ +  +
Sbjct: 363 HTIQVDVN--NDNIYIHKGDLVGRFKVAQFHFHWGRNNNEGSEHTHNGRKYPLELHIVHY 420

Query: 544 RSEYMTQEEALRHPDGVVMICYLIKV 621
              Y +  +A    DG+ ++ +  ++
Sbjct: 421 NESYGSLAKAAGMFDGLAVVGFWFEI 446


>UniRef50_Q9Y2D0 Cluster: Carbonic anhydrase 5B, mitochondrial
           precursor; n=31; Tetrapoda|Rep: Carbonic anhydrase 5B,
           mitochondrial precursor - Homo sapiens (Human)
          Length = 317

 Score = 64.1 bits (149), Expect = 3e-09
 Identities = 37/128 (28%), Positives = 65/128 (50%), Gaps = 2/128 (1%)
 Frame = +1

Query: 244 GHLPTPINVSITGSIPYTCPELKWYNFDVFPHK-VKLSNTGYTVLIGAKWKAERPYLEGG 420
           G   +PIN+    S+ Y  P LK       P   + + N GY+ L+  +   ++  ++GG
Sbjct: 61  GDRQSPINIRWRDSV-YD-PGLKPLTISYDPATCLHVWNNGYSFLVEFEDSTDKSVIKGG 118

Query: 421 PFQDKHIFSQIHFHWGADMMEGSDHTVDDRRYPGEMQVTFFRS-EYMTQEEALRHPDGVV 597
           P +  +   Q HFHWGA    GS+HTVD + +P E+ +  + +  +   E+A    +G+ 
Sbjct: 119 PLEHNYRLKQFHFHWGAIDAWGSEHTVDSKCFPAELHLVHWNAVRFENFEDAALEENGLA 178

Query: 598 MICYLIKV 621
           +I   +K+
Sbjct: 179 VIGVFLKL 186


>UniRef50_Q8N1Q1 Cluster: Carbonic anhydrase 13; n=133;
           Vertebrata|Rep: Carbonic anhydrase 13 - Homo sapiens
           (Human)
          Length = 262

 Score = 64.1 bits (149), Expect = 3e-09
 Identities = 37/141 (26%), Positives = 66/141 (46%), Gaps = 2/141 (1%)
 Frame = +1

Query: 205 GTLQWIYYWSDFEGHLPTPINVSITGSIPYTCPELKWYNFDVFPHKVKL-SNTGYTVLIG 381
           G + W  ++   +G   +PI +  T  + Y    L+  +    P   K+ SN+G++  + 
Sbjct: 13  GPIHWKEFFPIADGDQQSPIEIK-TKEVKYDS-SLRPLSIKYDPSSAKIISNSGHSFNVD 70

Query: 382 AKWKAERPYLEGGPFQDKHIFSQIHFHWGADMMEGSDHTVDDRRYPGEMQVTFFRSE-YM 558
                 +  L GGP    +   Q+H HWG+    GS+H VD   Y  E+ V  + S+ Y 
Sbjct: 71  FDDTENKSVLRGGPLTGSYRLRQVHLHWGSADDHGSEHIVDGVSYAAELHVVHWNSDKYP 130

Query: 559 TQEEALRHPDGVVMICYLIKV 621
           +  EA   PDG+ ++   +++
Sbjct: 131 SFVEAAHEPDGLAVLGVFLQI 151


>UniRef50_UPI0000E46DA6 Cluster: PREDICTED: similar to Carbonic
           anhydrase 8; n=1; Strongylocentrotus purpuratus|Rep:
           PREDICTED: similar to Carbonic anhydrase 8 -
           Strongylocentrotus purpuratus
          Length = 312

 Score = 63.7 bits (148), Expect = 4e-09
 Identities = 46/150 (30%), Positives = 73/150 (48%), Gaps = 6/150 (4%)
 Frame = +1

Query: 205 GTLQWIYYWSDFEGHLPTPINVSITGSI---PYTCPELKWYNFDVFPHKVKLSNTGYTVL 375
           GT +W  ++ +  G   +PI+++   ++       P L+  N+ +      L NTG  + 
Sbjct: 54  GTAEWGIHFQEANGDCQSPIDINSREAVYREGLNQPPLE-VNYALC-RDCDLINTGTGIQ 111

Query: 376 IGAKWKAERPYLEGGPFQDKHIF--SQIHFHWGADMMEGSDHTVDDRRYPGEMQVTFFRS 549
           I  K+K   P L GGP      F  +   FHWG     GS+HTV+ + YP E+ +  + S
Sbjct: 112 IIFKYK---PVLSGGPLPQNSKFELAACAFHWGQKDDRGSEHTVNFKAYPMELHLIHWNS 168

Query: 550 E-YMTQEEALRHPDGVVMICYLIKVVRSES 636
             Y T EEA+  P G+ +I   I+V R  +
Sbjct: 169 STYSTLEEAMGKPHGISIIALFIQVGREHA 198


>UniRef50_Q16W62 Cluster: Carbonic anhydrase II, putative; n=3;
           Aedes aegypti|Rep: Carbonic anhydrase II, putative -
           Aedes aegypti (Yellowfever mosquito)
          Length = 315

 Score = 63.7 bits (148), Expect = 4e-09
 Identities = 35/126 (27%), Positives = 62/126 (49%)
 Frame = +1

Query: 244 GHLPTPINVSITGSIPYTCPELKWYNFDVFPHKVKLSNTGYTVLIGAKWKAERPYLEGGP 423
           G   +PI++++  ++    P+  + N+D       L N G+T+ + A   +   Y  GG 
Sbjct: 53  GRRQSPIDLNMKAAVKGAYPQFVFDNYDQVMRNASLVNNGHTIQVYAGEVSASVY--GGG 110

Query: 424 FQDKHIFSQIHFHWGADMMEGSDHTVDDRRYPGEMQVTFFRSEYMTQEEALRHPDGVVMI 603
            ++K+I  Q HFHW       S+HT+ D+RY  E+ +    S+Y +  +A     GV ++
Sbjct: 111 LRNKYILEQFHFHWS------SEHTIADQRYALEVHLVHRNSKYASLTDAAAEKGGVAVL 164

Query: 604 CYLIKV 621
             L  V
Sbjct: 165 AVLFHV 170


>UniRef50_Q8V4Y0 Cluster: Cell surface-binding protein; n=32;
           Orthopoxvirus|Rep: Cell surface-binding protein -
           Monkeypox virus
          Length = 304

 Score = 63.7 bits (148), Expect = 4e-09
 Identities = 38/124 (30%), Positives = 65/124 (52%), Gaps = 2/124 (1%)
 Frame = +1

Query: 256 TPINVSITGSIPYTCPELKWYNFDVFPHK-VKLSNTGYTVLIGAKWKAERPYLEGGPFQD 432
           +PIN+    +I  T   LK  +      K   + NTG  V I  K      Y+ GG   +
Sbjct: 6   SPINIETKKAISDT--RLKTLDIHYNESKPTTIQNTGKLVRINFKGG----YISGGFLPN 59

Query: 433 KHIFSQIHFHWGADMMEGSDHTVDDRRYPGEMQVTFF-RSEYMTQEEALRHPDGVVMICY 609
           +++ S IH +WG +   GS+H +D  +Y GE+ +  + + +Y + EEA +H DG+++I  
Sbjct: 60  EYVLSTIHIYWGKEDDYGSNHLIDVYKYSGEINLVHWNKKKYSSYEEAKKHDDGIIIIAI 119

Query: 610 LIKV 621
            ++V
Sbjct: 120 FLQV 123


>UniRef50_UPI0000DB7206 Cluster: PREDICTED: similar to CG3940-PA;
           n=2; Apis mellifera|Rep: PREDICTED: similar to CG3940-PA
           - Apis mellifera
          Length = 491

 Score = 63.3 bits (147), Expect = 5e-09
 Identities = 37/134 (27%), Positives = 65/134 (48%), Gaps = 2/134 (1%)
 Frame = +1

Query: 226 YWSDF--EGHLPTPINVSITGSIPYTCPELKWYNFDVFPHKVKLSNTGYTVLIGAKWKAE 399
           YW      G   +PIN+    +      ELK+  +D F  + K++N G++V +  +    
Sbjct: 60  YWPGLCVTGKKQSPINIVTEDTFNTDIGELKFIRYD-FAFECKITNNGHSVQL--QLSGV 116

Query: 400 RPYLEGGPFQDKHIFSQIHFHWGADMMEGSDHTVDDRRYPGEMQVTFFRSEYMTQEEALR 579
             +LEG   +  +I  QIHFHW A      +HTVD+ R   E+    ++ +Y     A +
Sbjct: 117 PVHLEGANLESTYILEQIHFHWPA------EHTVDNNRDALELHFVHYKEQYGNTSAASK 170

Query: 580 HPDGVVMICYLIKV 621
           H +G+ ++  L ++
Sbjct: 171 HENGIAVVATLFEL 184


>UniRef50_Q9V9Y7 Cluster: CG18672-PA; n=1; Drosophila
           melanogaster|Rep: CG18672-PA - Drosophila melanogaster
           (Fruit fly)
          Length = 235

 Score = 63.3 bits (147), Expect = 5e-09
 Identities = 21/79 (26%), Positives = 46/79 (58%)
 Frame = +1

Query: 400 RPYLEGGPFQDKHIFSQIHFHWGADMMEGSDHTVDDRRYPGEMQVTFFRSEYMTQEEALR 579
           +P++ GG  + ++    +HFHWG+    GS+H ++ RR+  E+ +     +Y    +A+R
Sbjct: 46  KPFITGGRLKGRYYADGLHFHWGSYKSRGSEHLINKRRFDAEIHIVHRNEKYRNIAQAVR 105

Query: 580 HPDGVVMICYLIKVVRSES 636
             DG+ ++  ++ +VR ++
Sbjct: 106 QKDGLAVVAIMVAIVRKDN 124


>UniRef50_Q0QBU7 Cluster: Carbonic anhydrase; n=4; Echinoida|Rep:
           Carbonic anhydrase - Strongylocentrotus purpuratus
           (Purple sea urchin)
          Length = 182

 Score = 62.1 bits (144), Expect = 1e-08
 Identities = 27/72 (37%), Positives = 45/72 (62%), Gaps = 2/72 (2%)
 Frame = +1

Query: 409 LEGG--PFQDKHIFSQIHFHWGADMMEGSDHTVDDRRYPGEMQVTFFRSEYMTQEEALRH 582
           L+GG  PF  K   +Q+HFHWG     GS+HT+D R +  E+ +  + ++Y T  EA++ 
Sbjct: 7   LKGGGLPFDAKP--AQLHFHWGTTPERGSEHTIDGRPFSAELHLVHYNAKYRTIAEAVKQ 64

Query: 583 PDGVVMICYLIK 618
           PDG+ ++ + I+
Sbjct: 65  PDGLAVLGFFIQ 76


>UniRef50_P35219 Cluster: Carbonic anhydrase-related protein; n=20;
           Euteleostomi|Rep: Carbonic anhydrase-related protein -
           Homo sapiens (Human)
          Length = 290

 Score = 62.1 bits (144), Expect = 1e-08
 Identities = 42/160 (26%), Positives = 79/160 (49%), Gaps = 7/160 (4%)
 Frame = +1

Query: 163 KETPNEEAEKVPLYGT---LQWIYYWSDFEGHLPTPINV-SITGSIPYTCPELKWYNFDV 330
           KE   EE E+   +G    ++W   + D  G   +PIN+ S       +  +++     V
Sbjct: 16  KEEDEEEEEEGVEWGYEEGVEWGLVFPDANGEYQSPINLNSREARYDPSLLDVRLSPNYV 75

Query: 331 FPHKVKLSNTGYTVLIGAKWKAERPYLEGGPFQDKHIFS--QIHFHWGADMMEGSDHTVD 504
                +++N G+T+ +  K K+    L GGP    H F   ++ FHWG +   GS+HTV+
Sbjct: 76  VCRDCEVTNDGHTIQVILKSKS---VLSGGPLPQGHEFELYEVRFHWGRENQRGSEHTVN 132

Query: 505 DRRYPGEMQVTFFRSE-YMTQEEALRHPDGVVMICYLIKV 621
            + +P E+ +  + S  + + +EA+  P G+ +I   +++
Sbjct: 133 FKAFPMELHLIHWNSTLFGSIDEAVGKPHGIAIIALFVQI 172


>UniRef50_Q99N23 Cluster: Carbonic anhydrase 15 precursor; n=4;
           Eutheria|Rep: Carbonic anhydrase 15 precursor - Mus
           musculus (Mouse)
          Length = 324

 Score = 62.1 bits (144), Expect = 1e-08
 Identities = 39/144 (27%), Positives = 66/144 (45%), Gaps = 4/144 (2%)
 Frame = +1

Query: 196 PLYGTLQWIYYWSDFEGHLPTPINVSIT-GSIPYTCPELKWYNFDVFPHKV-KLSNTGYT 369
           P  G   W        G   +PIN+ +      YT     +  +D  P     L N G+T
Sbjct: 32  PKCGPAHWKELAPACGGPTQSPINIDLRLVQRDYTLKPFIFQGYDSAPQDPWVLENDGHT 91

Query: 370 VLIGAKWKAER-PYLEG-GPFQDKHIFSQIHFHWGADMMEGSDHTVDDRRYPGEMQVTFF 543
           VL+      +  P + G G    ++   Q+HFHWG+   +GS+H++D++    EM +   
Sbjct: 92  VLLRVNSCQQNCPAIRGAGLPSPEYRLLQLHFHWGSPGHQGSEHSLDEKHGSMEMHMVHM 151

Query: 544 RSEYMTQEEALRHPDGVVMICYLI 615
            ++Y + E+A   PDG  ++  L+
Sbjct: 152 NTKYQSMEDARSQPDGFAILAVLL 175


>UniRef50_Q27504 Cluster: Putative carbonic anhydrase 3; n=2;
           Caenorhabditis|Rep: Putative carbonic anhydrase 3 -
           Caenorhabditis elegans
          Length = 246

 Score = 60.9 bits (141), Expect = 3e-08
 Identities = 32/99 (32%), Positives = 54/99 (54%), Gaps = 2/99 (2%)
 Frame = +1

Query: 244 GHLPTPINVSITGSIPY--TCPELKWYNFDVFPHKVKLSNTGYTVLIGAKWKAERPYLEG 417
           G   +PIN+ + G +    T   +K+ N+D  P +  + N G++V +  + ++E P + G
Sbjct: 21  GQHQSPINIDL-GEVERKDTHDGIKFVNYD-HPIQGDIVNNGHSVQMTPELRSEHPEIYG 78

Query: 418 GPFQDKHIFSQIHFHWGADMMEGSDHTVDDRRYPGEMQV 534
           G     +   Q HFHWG +  EGS+HT+   RYP E+ +
Sbjct: 79  GGLDQVYRLVQYHFHWGENDNEGSEHTLGGLRYPAELHL 117


>UniRef50_Q4FCT9 Cluster: Carbonic anhydrase 4; n=1; Squalus
           acanthias|Rep: Carbonic anhydrase 4 - Squalus acanthias
           (Spiny dogfish)
          Length = 306

 Score = 60.5 bits (140), Expect = 4e-08
 Identities = 24/91 (26%), Positives = 51/91 (56%)
 Frame = +1

Query: 340 KVKLSNTGYTVLIGAKWKAERPYLEGGPFQDKHIFSQIHFHWGADMMEGSDHTVDDRRYP 519
           K  ++N G++V +  K       ++GG   +++   Q H+HWG  +  GS+HT+D  +YP
Sbjct: 81  KWTITNNGHSVQVTLKGDIA---IKGGDLPNRYKAVQFHYHWGTKVDPGSEHTIDGEQYP 137

Query: 520 GEMQVTFFRSEYMTQEEALRHPDGVVMICYL 612
            E+ +     +Y    +A++ P+G+ ++ ++
Sbjct: 138 MELHIVHMNEKYSDINDAVKDPEGLAVLGFM 168


>UniRef50_Q9XZG6 Cluster: Carbonic anhydrase; n=1; Anthopleura
           elegantissima|Rep: Carbonic anhydrase - Anthopleura
           elegantissima (Sea anemone)
          Length = 261

 Score = 60.5 bits (140), Expect = 4e-08
 Identities = 26/92 (28%), Positives = 52/92 (56%), Gaps = 1/92 (1%)
 Frame = +1

Query: 349 LSNTGYTVLIGAKWKAERPYLEGGPFQDKHIFSQIHFHWGADMMEGSDHTVDDRRYPGEM 528
           ++N GY+++I  K  +E   L GGP +  + F Q HFHWG     GS+H +D + +P E+
Sbjct: 62  VTNNGYSLVISRK-TSEGTNLSGGPLEHNYRFEQFHFHWGKTSGSGSEHLLDGKAFPAEL 120

Query: 529 QVTFFRSE-YMTQEEALRHPDGVVMICYLIKV 621
            +  + ++ + +  EA    +G+ ++   +++
Sbjct: 121 HLVHWNTDLFSSFGEAASSKNGLAVLGAFVQI 152


>UniRef50_UPI0000D55661 Cluster: PREDICTED: similar to CG11284-PA;
           n=1; Tribolium castaneum|Rep: PREDICTED: similar to
           CG11284-PA - Tribolium castaneum
          Length = 268

 Score = 60.1 bits (139), Expect = 5e-08
 Identities = 29/110 (26%), Positives = 52/110 (47%), Gaps = 1/110 (0%)
 Frame = +1

Query: 349 LSNTGYTVLIGAKWKAERPYLEGGPF-QDKHIFSQIHFHWGADMMEGSDHTVDDRRYPGE 525
           L+N G+T  +  +   E P L GGP  +D++IF Q+HFHW  D   G +H  + + +  E
Sbjct: 57  LNNNGFTATLRFQ-NREMPVLVGGPLHEDQYIFEQLHFHWSDDDHSGCEHIFEGQAFSME 115

Query: 526 MQVTFFRSEYMTQEEALRHPDGVVMICYLIKVVRSES*QTFKLGSRRILK 675
                +  +Y   + A    DG+ ++ + +K    +    F   +  + K
Sbjct: 116 AHAVHYNKKYGDFKNAADRHDGLAVVAFFLKATDDDEHPCFNKMTEAVKK 165


>UniRef50_UPI0000ECA9F1 Cluster: UPI0000ECA9F1 related cluster; n=1;
           Gallus gallus|Rep: UPI0000ECA9F1 UniRef100 entry -
           Gallus gallus
          Length = 257

 Score = 60.1 bits (139), Expect = 5e-08
 Identities = 29/93 (31%), Positives = 49/93 (52%), Gaps = 1/93 (1%)
 Frame = +1

Query: 334 PHKVKLSNTGYTVLIGAKWKAERPYLEGGPFQDKHIFSQIHFHWGADMMEGSDHTVDDRR 513
           P  V L +    + + ++  AE   + GG    ++   Q+HFHWG+    GS+HTVD ++
Sbjct: 81  PSPVPLLSFAVMLSLESEPGAEHIAISGGGLPGRYRALQLHFHWGSLSTNGSEHTVDGQQ 140

Query: 514 YPGEMQVTFFRSEYMTQEEALRHPDGVVMI-CY 609
            P E+ +     +Y T  EA  HP G+ ++ C+
Sbjct: 141 LPMELHIVHINVKYRTLGEAKGHPSGLAVLGCF 173


>UniRef50_Q9V396 Cluster: CG7820-PA; n=9; Endopterygota|Rep:
           CG7820-PA - Drosophila melanogaster (Fruit fly)
          Length = 270

 Score = 60.1 bits (139), Expect = 5e-08
 Identities = 43/144 (29%), Positives = 64/144 (44%), Gaps = 6/144 (4%)
 Frame = +1

Query: 205 GTLQWIYYWSDFEGHLPTPINVSIT----GSIPYTCPELKWYNFDVFPHKVKLSNTGYTV 372
           G   W   +    GH  +P++++ +    GS     P LKW    V  H   L N GY  
Sbjct: 12  GPAHWAKEYPQASGHRQSPVDITPSSAKKGSELNVAP-LKWKY--VPEHTKSLVNPGYCW 68

Query: 373 LIGAKWKAERPYLEGGPFQDKHI-FSQIHFHWGADMMEGSDHTVDDRRYPGEMQVTFFR- 546
            +          L GGP  D+     Q H HWG    +GS+HTVD   Y GE+ +  +  
Sbjct: 69  RVDVNGADSE--LTGGPLGDQIFKLEQFHCHWGCTDSKGSEHTVDGVSYSGELHLVHWNT 126

Query: 547 SEYMTQEEALRHPDGVVMICYLIK 618
           ++Y +  EA   PDG+ ++   +K
Sbjct: 127 TKYKSFGEAAAAPDGLAVLGVFLK 150


>UniRef50_Q9W2Q2 Cluster: CG9235-PA; n=3; Sophophora|Rep: CG9235-PA
           - Drosophila melanogaster (Fruit fly)
          Length = 332

 Score = 59.7 bits (138), Expect = 6e-08
 Identities = 34/120 (28%), Positives = 57/120 (47%), Gaps = 1/120 (0%)
 Frame = +1

Query: 256 TPINVSITG-SIPYTCPELKWYNFDVFPHKVKLSNTGYTVLIGAKWKAERPYLEGGPFQD 432
           +PIN+ +    I Y    L W +++  P  ++L N G+T+++ A +    P ++GG    
Sbjct: 101 SPINIDMNCVEINYFDTPLIWSHYNSIPLGIRLENNGHTLILRAAFPERTPSIDGGDLLG 160

Query: 433 KHIFSQIHFHWGADMMEGSDHTVDDRRYPGEMQVTFFRSEYMTQEEALRHPDGVVMICYL 612
           +  F +I F W      GS+HT+D    P EMQ      +     +      GV+MI Y+
Sbjct: 161 RFDFREISFRWSWASSLGSEHTLDHHHSPLEMQCLHTDGDGC---DGCSSSQGVLMISYM 217


>UniRef50_Q9VH26 Cluster: CG3940-PA; n=3; Sophophora|Rep: CG3940-PA
           - Drosophila melanogaster (Fruit fly)
          Length = 304

 Score = 59.7 bits (138), Expect = 6e-08
 Identities = 36/126 (28%), Positives = 60/126 (47%)
 Frame = +1

Query: 244 GHLPTPINVSITGSIPYTCPELKWYNFDVFPHKVKLSNTGYTVLIGAKWKAERPYLEGGP 423
           G   +PIN+ + G++      LK+ N+D     +++ N G+++ +   +  E   L GG 
Sbjct: 45  GKKQSPINLHVKGALKGEFDALKFENYDEHQKNLRMVNNGHSIQLSG-FDHELT-LSGGA 102

Query: 424 FQDKHIFSQIHFHWGADMMEGSDHTVDDRRYPGEMQVTFFRSEYMTQEEALRHPDGVVMI 603
                +  QIH HW       S+HT++D RYP E+ +    + Y     A    DG+V+I
Sbjct: 103 LLQDFVVEQIHMHWW------SEHTINDIRYPLEVHIVHRNTIYPNMTMAANFKDGIVVI 156

Query: 604 CYLIKV 621
             L  V
Sbjct: 157 GVLYHV 162


>UniRef50_Q8IMV4 Cluster: CG10899-PA, isoform A; n=5;
           Sophophora|Rep: CG10899-PA, isoform A - Drosophila
           melanogaster (Fruit fly)
          Length = 279

 Score = 59.7 bits (138), Expect = 6e-08
 Identities = 39/144 (27%), Positives = 69/144 (47%), Gaps = 5/144 (3%)
 Frame = +1

Query: 229 WSDFEGHLPTPINVSITGSIPYTCPELKWYNFDV-FPHKVKLSNTGYTVL--IGAKWKAE 399
           W+   G   +PI +    +I    P+LK+ N+       + + N G TVL  I       
Sbjct: 30  WNVKCGERQSPIALWSCNAITCNVPKLKFLNYHKSLCDPLSVINNGLTVLMRIPKTVDGS 89

Query: 400 RPYLEGGPFQDKHIFS--QIHFHWGADMMEGSDHTVDDRRYPGEMQVTFFRSEYMTQEEA 573
           RP L     + + +F   Q+HFHWG+ + +GS+H +D   Y GE+ +    + Y + +EA
Sbjct: 90  RPSLCIST-EGQQVFEADQLHFHWGSALSKGSEHCLDGNYYDGEVHIVHKNASYKSNKEA 148

Query: 574 LRHPDGVVMICYLIKVVRSES*QT 645
              P+G  ++   I+ +   + +T
Sbjct: 149 GLQPNGFAVLALFIRNLEDPNIET 172


>UniRef50_Q6WLH6 Cluster: Carbonic anhydrase; n=2; Anopheles
           gambiae|Rep: Carbonic anhydrase - Anopheles gambiae
           (African malaria mosquito)
          Length = 309

 Score = 59.7 bits (138), Expect = 6e-08
 Identities = 34/126 (26%), Positives = 68/126 (53%)
 Frame = +1

Query: 244 GHLPTPINVSITGSIPYTCPELKWYNFDVFPHKVKLSNTGYTVLIGAKWKAERPYLEGGP 423
           G   +PI+++I  ++      L + N+ +   + +++NTG+++ I  +  A    ++GG 
Sbjct: 47  GRRQSPIDLTIAAAVRGQFAPLFFSNYMLPLKQPRVTNTGHSIQINNRDSAIT--MQGGG 104

Query: 424 FQDKHIFSQIHFHWGADMMEGSDHTVDDRRYPGEMQVTFFRSEYMTQEEALRHPDGVVMI 603
              + +  Q+HFHWG      S+HT+DD RY  E+ +    + Y + E+A++  +GV ++
Sbjct: 105 LGGRFVLDQMHFHWG------SEHTLDDTRYGLELHLVHHDTRYASLEDAVQARNGVAVL 158

Query: 604 CYLIKV 621
             L  V
Sbjct: 159 GVLFHV 164


>UniRef50_Q16RN9 Cluster: Carbonic anhydrase II, putative; n=1;
           Aedes aegypti|Rep: Carbonic anhydrase II, putative -
           Aedes aegypti (Yellowfever mosquito)
          Length = 340

 Score = 59.3 bits (137), Expect = 9e-08
 Identities = 40/145 (27%), Positives = 66/145 (45%), Gaps = 2/145 (1%)
 Frame = +1

Query: 202 YGTLQWIYYWSDFEGHLPTPINVSITGSIPYTCPE-LKWYNFDVFPHKVKLSNTGYTVLI 378
           YG   W    +  EG   +PIN+    S+       L+       P  + + N G     
Sbjct: 95  YGPSNWGALNATCEGMYQSPINLIANRSVIVQQKRALELKGSRNVPMAMVVENEGGAAAF 154

Query: 379 GAKWKA-ERPYLEGGPFQDKHIFSQIHFHWGADMMEGSDHTVDDRRYPGEMQVTFFRSEY 555
             +++  E+P L GGP + +++F Q H+H G      S+HT D +RY  EM + F+   Y
Sbjct: 155 FPEFRTNEQPRLRGGPLRGEYLFYQFHYHLG------SEHTFDKKRYSAEMHLVFYNELY 208

Query: 556 MTQEEALRHPDGVVMICYLIKVVRS 630
            + + A    +GV +I     V++S
Sbjct: 209 GSFKAARDQANGVAVIALTFDVLKS 233


>UniRef50_UPI0000E48EBE Cluster: PREDICTED: hypothetical protein;
           n=2; Strongylocentrotus purpuratus|Rep: PREDICTED:
           hypothetical protein - Strongylocentrotus purpuratus
          Length = 239

 Score = 58.8 bits (136), Expect = 1e-07
 Identities = 26/75 (34%), Positives = 45/75 (60%), Gaps = 1/75 (1%)
 Frame = +1

Query: 406 YLEGGPFQDKHIFSQIHFHWGADMMEGSDHTVDDRRYPGEMQVTFFRSE-YMTQEEALRH 582
           Y+  GP   ++   +I  H+G +   GS+HTV  R +PGE+Q+ FF  + Y +  +A + 
Sbjct: 107 YISRGPLSYRYRLVEIRLHFGGENTHGSEHTVGGRAFPGELQLIFFNDDLYDSYGQAEKS 166

Query: 583 PDGVVMICYLIKVVR 627
           P+G+ ++   IKVV+
Sbjct: 167 PNGLAIMGLFIKVVK 181


>UniRef50_UPI0000E21B4D Cluster: PREDICTED: hypothetical protein
           isoform 1; n=1; Pan troglodytes|Rep: PREDICTED:
           hypothetical protein isoform 1 - Pan troglodytes
          Length = 208

 Score = 58.4 bits (135), Expect = 1e-07
 Identities = 33/108 (30%), Positives = 52/108 (48%), Gaps = 1/108 (0%)
 Frame = +1

Query: 205 GTLQWIYYWSDFEGHLPTPINVSITGSIPYTCPELKWYNFDVFPHKVK-LSNTGYTVLIG 381
           G  QW   +    G+  +P+++  + +   T   LK  +    P   K + N G++  + 
Sbjct: 13  GPEQWSKLYPIANGNNQSPVDIKTSETKHDT--SLKPISVSYNPATAKEIINVGHSFHVN 70

Query: 382 AKWKAERPYLEGGPFQDKHIFSQIHFHWGADMMEGSDHTVDDRRYPGE 525
            +    R  L+GGPF D +   Q HFHWG+    GS+HTVD  +Y  E
Sbjct: 71  FEDNDNRSVLKGGPFSDSYRLFQFHFHWGSTNEHGSEHTVDGVKYSAE 118


>UniRef50_UPI000044959A Cluster: PREDICTED: similar to carbonic
           anhydrase 4; n=1; Gallus gallus|Rep: PREDICTED: similar
           to carbonic anhydrase 4 - Gallus gallus
          Length = 316

 Score = 58.4 bits (135), Expect = 1e-07
 Identities = 34/134 (25%), Positives = 66/134 (49%), Gaps = 7/134 (5%)
 Frame = +1

Query: 241 EGHLPTPINVSITGSIPYT--CPELKWYNFDVF-PHKVKLSNTGYTVLIGAKWKAERPYL 411
           +G   +PIN+ +T ++ Y      L + N+DV    K K+ N G+TV +     +  P +
Sbjct: 50  KGSKQSPINI-VTKNVIYNKNLTPLHFENYDVKGSSKWKIENNGHTVKVTL---STNPKI 105

Query: 412 EGGPFQDKHIFSQIHFHWGADMME----GSDHTVDDRRYPGEMQVTFFRSEYMTQEEALR 579
            GG  + K+   + H HWG    +    GS+H++D  +   E+ +   R + +   +A  
Sbjct: 106 GGGGLKRKYKAIEFHLHWGVQEEQLYFPGSEHSIDGEKQAMELHIVHIREDVLNLADAKN 165

Query: 580 HPDGVVMICYLIKV 621
             DG+ ++ + +K+
Sbjct: 166 FTDGIAVLAFFVKI 179


>UniRef50_P23280 Cluster: Carbonic anhydrase 6 precursor; n=11;
           Eutheria|Rep: Carbonic anhydrase 6 precursor - Homo
           sapiens (Human)
          Length = 308

 Score = 58.4 bits (135), Expect = 1e-07
 Identities = 40/140 (28%), Positives = 66/140 (47%), Gaps = 5/140 (3%)
 Frame = +1

Query: 217 WIYYWSDFEGHLPTPINVSITGSIPYTCPELKWYN---FDVFPHKVKLSNTGYTVLIGAK 387
           W  ++    G   +PIN+  T  + Y  P LK  N   ++    +  + N G+TV I   
Sbjct: 35  WPQHYPACGGQRQSPINLQRT-KVRYN-PSLKGLNMTGYETQAGEFPMVNNGHTVQISLP 92

Query: 388 WKAERPYLEGGPFQDKHIFSQIHFHWGADMME--GSDHTVDDRRYPGEMQVTFFRSEYMT 561
                   +G  +    I  Q+HFHWG    E  GS+HTVD  R+  E+ +  + S+Y +
Sbjct: 93  STMRMTVADGTVY----IAQQMHFHWGGASSEISGSEHTVDGIRHVIEIHIVHYNSKYKS 148

Query: 562 QEEALRHPDGVVMICYLIKV 621
            + A   PDG+ ++   ++V
Sbjct: 149 YDIAQDAPDGLAVLAAFVEV 168


>UniRef50_Q1LY76 Cluster: Novel protein; n=4; Clupeocephala|Rep:
           Novel protein - Danio rerio (Zebrafish) (Brachydanio
           rerio)
          Length = 288

 Score = 58.0 bits (134), Expect = 2e-07
 Identities = 34/124 (27%), Positives = 63/124 (50%), Gaps = 2/124 (1%)
 Frame = +1

Query: 256 TPINVSITGSIPYTCPELKWYNFDVFPHKVK--LSNTGYTVLIGAKWKAERPYLEGGPFQ 429
           +PIN+       ++   L+ + F++  HK +  L+N G++V++      +   + GG   
Sbjct: 50  SPINLDHHLMKNHSLDSLQLHGFNL-THKGQWWLTNQGHSVVLEV---GDGMQVSGGGLP 105

Query: 430 DKHIFSQIHFHWGADMMEGSDHTVDDRRYPGEMQVTFFRSEYMTQEEALRHPDGVVMICY 609
             +   Q+HFHWG+    GS+HT+D  R+P EM +   +S +     AL  P G+ ++  
Sbjct: 106 ATYRTFQLHFHWGSVSSNGSEHTLDHLRFPMEMHIVNIKSTHPNLTSALEDPTGIAVLGV 165

Query: 610 LIKV 621
            + V
Sbjct: 166 FVDV 169


>UniRef50_UPI0000E47C8E Cluster: PREDICTED: similar to CG7820-PA;
           n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
           similar to CG7820-PA - Strongylocentrotus purpuratus
          Length = 266

 Score = 56.4 bits (130), Expect = 6e-07
 Identities = 35/141 (24%), Positives = 66/141 (46%), Gaps = 2/141 (1%)
 Frame = +1

Query: 205 GTLQWIYYWSDFEGHLPTPINVSITGSIPYTCPELKWYNFDVFPHKVK-LSNTGYTVLIG 381
           G   W   +    G   +PI+++ T +   T    +       P + K L N G+T  + 
Sbjct: 11  GPAHWHESFPQAGGKRQSPIDINTTDARFDTALVDRPLKISYDPSRTKALVNNGHTFRVD 70

Query: 382 AKWKAERPYLEGGPFQDKHIFSQIHFHWGADMMEGSDHTVDDRRYPGEMQVTFFRS-EYM 558
               A    L GGP +D +   Q H HWG +  EG++HT++ ++Y  E+ +  + + ++ 
Sbjct: 71  ID--ACDYNLSGGPLEDNYQLVQFHAHWGKEDKEGAEHTINGKQYAAEIHLVHWNTGQFK 128

Query: 559 TQEEALRHPDGVVMICYLIKV 621
              +A++   G+ ++   IKV
Sbjct: 129 AVSDAIKCDKGIAVLGSFIKV 149


>UniRef50_Q4RRY2 Cluster: Chromosome 7 SCAF15001, whole genome
           shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 7
           SCAF15001, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 268

 Score = 56.4 bits (130), Expect = 6e-07
 Identities = 23/70 (32%), Positives = 37/70 (52%)
 Frame = +1

Query: 409 LEGGPFQDKHIFSQIHFHWGADMMEGSDHTVDDRRYPGEMQVTFFRSEYMTQEEALRHPD 588
           L GG    ++  +Q HFHWG     GS+HT+D  R+P EM +   +  Y +  EA     
Sbjct: 62  LTGGGLSGQYRAAQFHFHWGGRGRPGSEHTIDGERFPMEMHIVHIKEPYGSLAEAEHDMA 121

Query: 589 GVVMICYLIK 618
           G+ ++ +L +
Sbjct: 122 GIALLAFLFE 131


>UniRef50_Q9W3P7 Cluster: CG1402-PA; n=3; Endopterygota|Rep:
           CG1402-PA - Drosophila melanogaster (Fruit fly)
          Length = 321

 Score = 56.4 bits (130), Expect = 6e-07
 Identities = 29/99 (29%), Positives = 52/99 (52%), Gaps = 4/99 (4%)
 Frame = +1

Query: 337 HKVK--LSNTGYTVLIGA-KWKAERPYLEGGPFQDKHIFSQIHFHWGADMMEGSDHTVDD 507
           HKV   L NTG +++    K   +   + GGP   ++ F +I+ H+G + + GS+H +  
Sbjct: 78  HKVSGTLHNTGQSLVFRVDKDTKQHVNISGGPLAYRYQFEEIYIHYGTENVRGSEHFIQG 137

Query: 508 RRYPGEMQVTFFRSE-YMTQEEALRHPDGVVMICYLIKV 621
             +PGE+Q+  F  E Y    EA     G+V +  ++++
Sbjct: 138 YSFPGEIQIYGFNKELYHNMSEAQHKSQGIVGLSLMVQI 176


>UniRef50_Q29QI5 Cluster: IP04174p; n=4; Endopterygota|Rep: IP04174p
           - Drosophila melanogaster (Fruit fly)
          Length = 333

 Score = 56.4 bits (130), Expect = 6e-07
 Identities = 29/99 (29%), Positives = 52/99 (52%), Gaps = 4/99 (4%)
 Frame = +1

Query: 337 HKVK--LSNTGYTVLIGA-KWKAERPYLEGGPFQDKHIFSQIHFHWGADMMEGSDHTVDD 507
           HKV   L NTG +++    K   +   + GGP   ++ F +I+ H+G + + GS+H +  
Sbjct: 90  HKVSGTLHNTGQSLVFRVDKDTKQHVNISGGPLAYRYQFEEIYIHYGTENVRGSEHFIQG 149

Query: 508 RRYPGEMQVTFFRSE-YMTQEEALRHPDGVVMICYLIKV 621
             +PGE+Q+  F  E Y    EA     G+V +  ++++
Sbjct: 150 YSFPGEIQIYGFNKELYHNMSEAQHKSQGIVGLSLMVQI 188


>UniRef50_UPI00015B6431 Cluster: PREDICTED: similar to CG1402-PA;
           n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
           CG1402-PA - Nasonia vitripennis
          Length = 488

 Score = 56.0 bits (129), Expect = 8e-07
 Identities = 39/131 (29%), Positives = 68/131 (51%), Gaps = 4/131 (3%)
 Frame = +1

Query: 241 EGHLPTPINVSITGSIPYTCPELKWYNFDVFPHKVK--LSNTGYTVLIGAKWKAE-RPYL 411
           +G   +PIN+     + +  P L+  + D   HKV   L NTG  ++  A  +++ R  +
Sbjct: 172 KGRRQSPINIE-PDKLLFD-PHLRPVHVD--KHKVSGHLHNTGQFLVFRADKESKVRVNI 227

Query: 412 EGGPFQDKHIFSQIHFHWGADMMEGSDHTVDDRRYPGEMQVTFFRSE-YMTQEEALRHPD 588
            GGP    + F +I+ H+G D   GS+H V++  +P E+Q+  F +E Y    EA     
Sbjct: 228 TGGPLAYHYQFEEIYIHYGQDDNHGSEHRVNNYAFPAEIQLYGFNAELYHNMSEAQHKSQ 287

Query: 589 GVVMICYLIKV 621
           G+V I  ++++
Sbjct: 288 GLVAISLMVQL 298


>UniRef50_Q4SLF0 Cluster: Chromosome 7 SCAF14557, whole genome
           shotgun sequence; n=6; Clupeocephala|Rep: Chromosome 7
           SCAF14557, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 358

 Score = 56.0 bits (129), Expect = 8e-07
 Identities = 32/122 (26%), Positives = 57/122 (46%), Gaps = 2/122 (1%)
 Frame = +1

Query: 244 GHLPTPINVSITGSIPYTCPELKWYNFDVFPHKVK--LSNTGYTVLIGAKWKAERPYLEG 417
           G   +PINV    ++  +   L  + FD +    +  + N G++V +     +    + G
Sbjct: 50  GSYQSPINVVTKKAVKDS--RLTAFQFDNYQQIFRGTIKNNGHSVQVDVPHLS---IISG 104

Query: 418 GPFQDKHIFSQIHFHWGADMMEGSDHTVDDRRYPGEMQVTFFRSEYMTQEEALRHPDGVV 597
           G     +   Q H HWG++   GS+HT+D  +YP E+ +   +  Y     AL  P+GV 
Sbjct: 105 GGLTTSYKAVQFHLHWGSNGGPGSEHTIDGEQYPMELHIVHMKHHYTDLTTALADPEGVA 164

Query: 598 MI 603
           ++
Sbjct: 165 VL 166


>UniRef50_UPI0000D575C0 Cluster: PREDICTED: similar to CG5379-PA;
           n=1; Tribolium castaneum|Rep: PREDICTED: similar to
           CG5379-PA - Tribolium castaneum
          Length = 298

 Score = 55.6 bits (128), Expect = 1e-06
 Identities = 32/121 (26%), Positives = 61/121 (50%)
 Frame = +1

Query: 241 EGHLPTPINVSITGSIPYTCPELKWYNFDVFPHKVKLSNTGYTVLIGAKWKAERPYLEGG 420
           +G   +PIN+S   +     P   +  +D   ++ ++ N+G+T  I  K  A +P + GG
Sbjct: 40  KGKQQSPINLSRQMATETLFPSFIFEYYDEI-YRAEIKNSGHTAQIQLK-VAVKPKVSGG 97

Query: 421 PFQDKHIFSQIHFHWGADMMEGSDHTVDDRRYPGEMQVTFFRSEYMTQEEALRHPDGVVM 600
                ++   +HFHW       S+HT+++ R+P E+ +  + S   +  EAL+   GV +
Sbjct: 98  GLLSTYVLDNMHFHWN------SEHTINEERFPLELHLVHYDSTKKSLAEALKVKGGVAV 151

Query: 601 I 603
           +
Sbjct: 152 L 152


>UniRef50_Q4S1J8 Cluster: Chromosome 6 SCAF14768, whole genome
           shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
           Chromosome 6 SCAF14768, whole genome shotgun sequence -
           Tetraodon nigroviridis (Green puffer)
          Length = 292

 Score = 55.6 bits (128), Expect = 1e-06
 Identities = 25/89 (28%), Positives = 45/89 (50%)
 Frame = +1

Query: 355 NTGYTVLIGAKWKAERPYLEGGPFQDKHIFSQIHFHWGADMMEGSDHTVDDRRYPGEMQV 534
           N G++  +      +   L  GP    +   Q HFHWGA   +GS+HTV  R +P E+ +
Sbjct: 61  NNGHSFQVTFADDRDSSTLTEGPITGIYRLKQFHFHWGASDDKGSEHTVAGRMFPAELHL 120

Query: 535 TFFRSEYMTQEEALRHPDGVVMICYLIKV 621
             + ++Y +  EA    DG+ ++   +++
Sbjct: 121 VHWNTKYGSFGEAASQADGLAVVGVFLQI 149


>UniRef50_Q32LW3 Cluster: LOC553246 protein; n=7; Clupeocephala|Rep:
           LOC553246 protein - Danio rerio (Zebrafish) (Brachydanio
           rerio)
          Length = 324

 Score = 55.6 bits (128), Expect = 1e-06
 Identities = 25/83 (30%), Positives = 43/83 (51%)
 Frame = +1

Query: 355 NTGYTVLIGAKWKAERPYLEGGPFQDKHIFSQIHFHWGADMMEGSDHTVDDRRYPGEMQV 534
           N G+TV I      +R  + G      +   Q+H HWG +   GS+HT+D  ++P E+ +
Sbjct: 106 NNGHTVQINLP---DRAKINGANLGSTYKAQQLHLHWGKNGGPGSEHTIDGEKFPMELHI 162

Query: 535 TFFRSEYMTQEEALRHPDGVVMI 603
              + EY + E+A+    GV ++
Sbjct: 163 VHIKEEYNSLEQAVGDSSGVAVL 185


>UniRef50_Q9Q8L7 Cluster: M83L; n=2; Leporipoxvirus|Rep: M83L -
           Myxoma virus
          Length = 286

 Score = 55.2 bits (127), Expect = 1e-06
 Identities = 23/70 (32%), Positives = 43/70 (61%)
 Frame = +1

Query: 409 LEGGPFQDKHIFSQIHFHWGADMMEGSDHTVDDRRYPGEMQVTFFRSEYMTQEEALRHPD 588
           L+GGP + K++ S++ F WG      S+H+V+   Y GE+Q+  +  +Y   ++A ++ D
Sbjct: 54  LQGGPLKSKYVLSELSFRWGR-----SEHSVNGAYYVGEVQMVHWNLKYANYDDARKYKD 108

Query: 589 GVVMICYLIK 618
           GVV++   +K
Sbjct: 109 GVVILAVFLK 118


>UniRef50_Q5DFH8 Cluster: SJCHGC06606 protein; n=1; Schistosoma
           japonicum|Rep: SJCHGC06606 protein - Schistosoma
           japonicum (Blood fluke)
          Length = 288

 Score = 55.2 bits (127), Expect = 1e-06
 Identities = 22/76 (28%), Positives = 41/76 (53%)
 Frame = +1

Query: 409 LEGGPFQDKHIFSQIHFHWGADMMEGSDHTVDDRRYPGEMQVTFFRSEYMTQEEALRHPD 588
           L GGP   ++  +Q H HWG+    GS+H ++    P E+   F  ++Y T E A+ + D
Sbjct: 74  LSGGPLTSEYKLAQFHLHWGSGNNWGSEHMINGISCPAELHCVFINTKYGTMETAITYSD 133

Query: 589 GVVMICYLIKVVRSES 636
           G+ ++    ++ +S +
Sbjct: 134 GLSVVGVFFQLGKSSN 149


>UniRef50_A3FFY1 Cluster: Cytoplasmic carbonic anydrase; n=1;
           Callinectes sapidus|Rep: Cytoplasmic carbonic anydrase -
           Callinectes sapidus (Blue crab)
          Length = 271

 Score = 55.2 bits (127), Expect = 1e-06
 Identities = 28/81 (34%), Positives = 44/81 (54%), Gaps = 6/81 (7%)
 Frame = +1

Query: 379 GAKWKAE----RPYLEGGPF-QDKHIFSQIHFHWGADMMEGSDHTVDDRRYPGEMQVTFF 543
           GA WKA+    R  L GGP   D+++  Q H HWG     GS+HTVD   YP E+ +  +
Sbjct: 62  GASWKAQIGSGRSSLRGGPLGDDEYVLEQFHPHWGKTNERGSEHTVDGTCYPAELHLVHW 121

Query: 544 -RSEYMTQEEALRHPDGVVMI 603
            +S++ +  +A     G+ ++
Sbjct: 122 NKSKFSSFAQAAASEGGLAVL 142


>UniRef50_Q16790 Cluster: Carbonic anhydrase 9 precursor; n=21;
           Theria|Rep: Carbonic anhydrase 9 precursor - Homo
           sapiens (Human)
          Length = 459

 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 38/162 (23%), Positives = 71/162 (43%), Gaps = 3/162 (1%)
 Frame = +1

Query: 142 EPKTDEVKETPNEEAEKVPLYGTLQWIYYWSDFEGHLPTPINV--SITGSIPYTCP-ELK 312
           EP+ +  ++   ++       G   W        G   +P+++   +    P   P EL 
Sbjct: 124 EPQNNAHRDKEGDDQSHWRYGGDPPWPRVSPACAGRFQSPVDIRPQLAAFCPALRPLELL 183

Query: 313 WYNFDVFPHKVKLSNTGYTVLIGAKWKAERPYLEGGPFQDKHIFSQIHFHWGADMMEGSD 492
            +     P +++L N G++V +      E      GP ++     Q+H HWGA    GS+
Sbjct: 184 GFQLPPLP-ELRLRNNGHSVQLTLPPGLEMAL---GPGREYRAL-QLHLHWGAAGRPGSE 238

Query: 493 HTVDDRRYPGEMQVTFFRSEYMTQEEALRHPDGVVMICYLIK 618
           HTV+  R+P E+ V    + +   +EAL  P G+ ++   ++
Sbjct: 239 HTVEGHRFPAEIHVVHLSTAFARVDEALGRPGGLAVLAAFLE 280


>UniRef50_Q21614 Cluster: Putative uncharacterized protein cah-4;
           n=3; Caenorhabditis|Rep: Putative uncharacterized
           protein cah-4 - Caenorhabditis elegans
          Length = 280

 Score = 53.6 bits (123), Expect = 4e-06
 Identities = 21/62 (33%), Positives = 36/62 (58%)
 Frame = +1

Query: 433 KHIFSQIHFHWGADMMEGSDHTVDDRRYPGEMQVTFFRSEYMTQEEALRHPDGVVMICYL 612
           K   +Q H HWG++  EGS+H +D ++  GE+   F+ + Y +   AL  PDG+ ++   
Sbjct: 114 KFALAQFHAHWGSNSKEGSEHFLDGKQLSGEVHFVFWNTSYESFNVALSKPDGLAVVGVF 173

Query: 613 IK 618
           +K
Sbjct: 174 LK 175


>UniRef50_A7SHT0 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 222

 Score = 53.6 bits (123), Expect = 4e-06
 Identities = 36/144 (25%), Positives = 69/144 (47%), Gaps = 4/144 (2%)
 Frame = +1

Query: 205 GTLQWIYYWSDFEGHLPTPINVSITGSIPYTCPELKWY--NFDVFPHKVK--LSNTGYTV 372
           G   W   + + +G   +PIN+ +T  +       ++   NF+ +   +   LSN G T+
Sbjct: 1   GPDDWASAYPECKGLAQSPINI-VTSKVTRVSRPFRYMKINFNNYNGGLACFLSNDGKTL 59

Query: 373 LIGAKWKAERPYLEGGPFQDKHIFSQIHFHWGADMMEGSDHTVDDRRYPGEMQVTFFRSE 552
               +        +G    D++    + FH+G +   GS+H VD RR+PGE+Q+ F  ++
Sbjct: 60  DFKVR--------QGLDPHDRYQLETVRFHFGCNDWLGSEHAVDGRRHPGEIQMIFHNTK 111

Query: 553 YMTQEEALRHPDGVVMICYLIKVV 624
           Y    +A    DG++++   ++ V
Sbjct: 112 YSNVSDAADKSDGLLVVAAFMRKV 135


>UniRef50_Q4SLZ9 Cluster: Chromosome 13 SCAF14555, whole genome
           shotgun sequence; n=7; Clupeocephala|Rep: Chromosome 13
           SCAF14555, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 229

 Score = 53.2 bits (122), Expect = 6e-06
 Identities = 38/130 (29%), Positives = 67/130 (51%), Gaps = 4/130 (3%)
 Frame = +1

Query: 244 GHLPTPINV-SITGSIPYTCPELKWYNFDVFPHK-VKLSNTGYTVLIGAKWKAERPYLEG 417
           G   +PIN+ S       T   +   N+++ P++ + L N G++  I    K    YL G
Sbjct: 30  GAFQSPINIMSDLMRFDPTLRPVDVRNYNLSPNEQLTLGNNGHSAQISLPSKM---YLLG 86

Query: 418 GPFQDKHIFSQIHFHWGADMM-EGSDHTVDDRRYPGEMQVTFFRSE-YMTQEEALRHPDG 591
                ++  +Q+HFHWG+     GS+H V++++Y  EM +  F S+ Y +   A+   DG
Sbjct: 87  --LHHRYSAAQLHFHWGSSSSPAGSEHMVNNKQYAAEMHIVHFNSDKYSSISMAVDKSDG 144

Query: 592 VVMICYLIKV 621
           + ++  LI+V
Sbjct: 145 LAVLGVLIEV 154


>UniRef50_Q9W316 Cluster: CG32698-PA; n=5; Endopterygota|Rep:
           CG32698-PA - Drosophila melanogaster (Fruit fly)
          Length = 327

 Score = 53.2 bits (122), Expect = 6e-06
 Identities = 31/116 (26%), Positives = 58/116 (50%), Gaps = 9/116 (7%)
 Frame = +1

Query: 301 PELKWYNFDVFPHKVKLSNTGYTVLIGAKWKAERPY--------LEGGPFQDKHIFSQIH 456
           P L+  + D       ++NTG++V+  A       Y        + GGP   ++ F +IH
Sbjct: 71  PNLRPMHIDKHRISGLITNTGHSVIFTAGNDTVANYDGMQTPVNISGGPLSYRYRFHEIH 130

Query: 457 FHWGADMMEGSDHTVDDRRYPGEMQVTFFRSE-YMTQEEALRHPDGVVMICYLIKV 621
            H+G +   GS+H+V+   +P E+Q+  + S+ Y    +AL    G+V +  L+++
Sbjct: 131 MHYGLNDQFGSEHSVEGYTFPAEIQIFGYNSQLYANFSDALNRAQGIVGVSILLQL 186


>UniRef50_O02637 Cluster: Carbonic anhydrase protein 6; n=3;
           Rhabditida|Rep: Carbonic anhydrase protein 6 -
           Caenorhabditis elegans
          Length = 319

 Score = 52.4 bits (120), Expect = 1e-05
 Identities = 19/63 (30%), Positives = 36/63 (57%)
 Frame = +1

Query: 427 QDKHIFSQIHFHWGADMMEGSDHTVDDRRYPGEMQVTFFRSEYMTQEEALRHPDGVVMIC 606
           ++++    ++FHW  + M GS+HT+    Y GEM +    + + T  +AL+ P+GV+ I 
Sbjct: 126 EEQYHLDAVNFHWATEPMNGSEHTIGGVGYAGEMHLIHRNTRFATMADALKQPNGVIAIA 185

Query: 607 YLI 615
             +
Sbjct: 186 VFL 188


>UniRef50_Q8MPH8 Cluster: Carbonic anhydrase; n=1; Riftia
           pachyptila|Rep: Carbonic anhydrase - Riftia pachyptila
           (Tube worm)
          Length = 243

 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 21/71 (29%), Positives = 40/71 (56%), Gaps = 1/71 (1%)
 Frame = +1

Query: 409 LEGGPFQDKHIFSQIHFHWGADMMEGSDHTVDDRRYPGEMQVTFFR-SEYMTQEEALRHP 585
           L GGP  +++  +  HFHW     EGS+HTV  + Y  E  +  +  ++Y + ++A++  
Sbjct: 71  LSGGPLGNEYKAASFHFHWSKTSAEGSEHTVAGKAYAAEAHIVHYNAAKYASFQDAVKAD 130

Query: 586 DGVVMICYLIK 618
           DG+ ++   I+
Sbjct: 131 DGLAVLATFIQ 141


>UniRef50_P18761 Cluster: Carbonic anhydrase 6 precursor; n=11;
           Euarchontoglires|Rep: Carbonic anhydrase 6 precursor -
           Mus musculus (Mouse)
          Length = 317

 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 42/144 (29%), Positives = 61/144 (42%), Gaps = 5/144 (3%)
 Frame = +1

Query: 205 GTLQWIYYWSDFEGHLPTPINVSITGSIPYTCPELK---WYNFDVFPHKVKLSNTGYTVL 375
           G  QW   +    G   +PI+V  T  + +  P LK     N++    +  ++N G+TV 
Sbjct: 30  GESQWSEQYPSCGGERQSPIDVK-TEEVMFN-PSLKPLSLVNYEKENLEFTMTNNGHTVS 87

Query: 376 IGAKWKAERPYLEGGPFQDKHIFSQIHFHWGADMME--GSDHTVDDRRYPGEMQVTFFRS 549
           I           +G  F  K      HFHWG    E  GS+HT+D  R   E     F  
Sbjct: 88  IDLPPSMYLETSDGTEFISK----AFHFHWGGRDWELSGSEHTIDGIRSIMEAHFVHFNK 143

Query: 550 EYMTQEEALRHPDGVVMICYLIKV 621
           EY T E A    +G+ ++  L K+
Sbjct: 144 EYGTYENAKDQKNGLAVLAVLFKI 167


>UniRef50_Q98936 Cluster: Receptor-type tyrosine-protein phosphatase
           gamma precursor; n=9; Amniota|Rep: Receptor-type
           tyrosine-protein phosphatase gamma precursor - Gallus
           gallus (Chicken)
          Length = 1422

 Score = 51.6 bits (118), Expect = 2e-05
 Identities = 34/120 (28%), Positives = 58/120 (48%), Gaps = 3/120 (2%)
 Frame = +1

Query: 202 YGTLQWIYYWSDFEGHLPTPIN-VSITGSIPYTCPELKWYNFD-VFPHKVKLSNTGYTVL 375
           YG   W+       G   +PI+ V     + Y   EL+   FD    +K  + NTG TV 
Sbjct: 66  YGPEHWVTSSEKCGGSHQSPIDIVDHQAHVLYEYQELQLDGFDNESSNKTWMKNTGKTVA 125

Query: 376 IGAKWKAERPYLEGGPFQDKHIFSQIHFHWG-ADMMEGSDHTVDDRRYPGEMQVTFFRSE 552
           I  K   +  ++ G     +    ++ FHWG ++   GS+H+++ +R+P EMQ+ F+  +
Sbjct: 126 ILLK---DDYFVSGAGLPGRFKAEKVEFHWGQSNGSAGSEHSINGKRFPVEMQIYFYNPD 182


>UniRef50_A1L3H6 Cluster: LOC100037010 protein; n=4; Xenopus|Rep:
           LOC100037010 protein - Xenopus laevis (African clawed
           frog)
          Length = 337

 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 30/93 (32%), Positives = 50/93 (53%), Gaps = 2/93 (2%)
 Frame = +1

Query: 349 LSNTGYTVLIGAKWKAERPYLEGGPFQDKHIFSQIHFHWGADMM-EGSDHTVDDRRYPGE 525
           LSN G+TV +          +E  PF   +  SQ+H HWG     +GS+H ++ +R+ GE
Sbjct: 80  LSNNGHTVQMSL---VPTMKIEIEPFH--YTASQLHLHWGQKSTPKGSEHCIEGKRFAGE 134

Query: 526 MQVTFFRSE-YMTQEEALRHPDGVVMICYLIKV 621
           + V  + S+ Y     A++  DG+ ++  LI+V
Sbjct: 135 VHVVHYNSDKYADLSTAMKESDGLAVLGILIEV 167


>UniRef50_Q6NZJ2 Cluster: Car10 protein; n=16; Euteleostomi|Rep:
           Car10 protein - Mus musculus (Mouse)
          Length = 304

 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 23/74 (31%), Positives = 42/74 (56%), Gaps = 1/74 (1%)
 Frame = +1

Query: 418 GPFQDKHIFSQIHFHWGADMMEGSDHTVDDRRYPGEMQVTFFRSE-YMTQEEALRHPDGV 594
           GP    H   +I  H+G++  +GS+H ++ + + GE+Q+  +  E Y    EA + P+G+
Sbjct: 96  GPMTYSHRLEEIRLHFGSEDSQGSEHLLNGQAFSGEVQLIHYNHELYTNVTEAAKSPNGL 155

Query: 595 VMICYLIKVVRSES 636
           V++   IKV  S +
Sbjct: 156 VVVSIFIKVSDSSN 169


>UniRef50_UPI0000F2BCDF Cluster: PREDICTED: similar to carbonic
           anhydrase IV; n=1; Monodelphis domestica|Rep: PREDICTED:
           similar to carbonic anhydrase IV - Monodelphis domestica
          Length = 237

 Score = 50.8 bits (116), Expect = 3e-05
 Identities = 26/100 (26%), Positives = 50/100 (50%), Gaps = 2/100 (2%)
 Frame = +1

Query: 241 EGHLPTPINVSITGSI--PYTCPELKWYNFDVFPHKVKLSNTGYTVLIGAKWKAERPYLE 414
           +G   +P+N+ I+ ++  P      K+ ++D   H   + N GYT+ +      +   + 
Sbjct: 32  KGFKQSPVNIVISNALSDPRLKVNFKYIDYDG-QHPWTIVNNGYTISVDLN---DTIKIS 87

Query: 415 GGPFQDKHIFSQIHFHWGADMMEGSDHTVDDRRYPGEMQV 534
           GG  +D +    + FHW   + +GS+HT++ + YP E  V
Sbjct: 88  GGGLEDTYRAMYVQFHWSDSLRKGSEHTINGKTYPMESHV 127


>UniRef50_UPI0000586D72 Cluster: PREDICTED: similar to Chain A,
           Crystal Structure Of The Extracellular Domain Of Murine
           Carbonic Anhydrase Xiv; n=6; Strongylocentrotus
           purpuratus|Rep: PREDICTED: similar to Chain A, Crystal
           Structure Of The Extracellular Domain Of Murine Carbonic
           Anhydrase Xiv - Strongylocentrotus purpuratus
          Length = 331

 Score = 50.4 bits (115), Expect = 4e-05
 Identities = 32/135 (23%), Positives = 61/135 (45%), Gaps = 4/135 (2%)
 Frame = +1

Query: 244 GHLPTPINVSITGSIPYTCPELKWYNFDVFPHKVKLSNTGYTVLIGAKWKAERPY-LEGG 420
           G   +PIN++ + +       L    +      +++ N G+ + +      E  Y L GG
Sbjct: 42  GTSQSPININTSIATHIDLGSLSPDGYTEANPNLEIVNNGHGITVQLHEAVEAFYTLSGG 101

Query: 421 PFQDKHIFSQIHFHWGADMMEGSDHTVDDRRYPGEMQVTFF-RSEYMTQEEALR--HPDG 591
                +  SQ HFHWG+   +GS+H ++   +P E+ +  + R++Y     AL     D 
Sbjct: 102 GLPTTYTASQFHFHWGSINSQGSEHLINSNAFPAELHMVHYDRAKYANLGAALTSLQWDA 161

Query: 592 VVMICYLIKVVRSES 636
           V  +  +I++   E+
Sbjct: 162 VTAVGVMIQIGEDEN 176


>UniRef50_UPI00004D5334 Cluster: Carbonic anhydrase 4 precursor (EC
           4.2.1.1) (Carbonic anhydrase IV) (Carbonate dehydratase
           IV) (CA-IV).; n=1; Xenopus tropicalis|Rep: Carbonic
           anhydrase 4 precursor (EC 4.2.1.1) (Carbonic anhydrase
           IV) (Carbonate dehydratase IV) (CA-IV). - Xenopus
           tropicalis
          Length = 276

 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 35/127 (27%), Positives = 57/127 (44%), Gaps = 3/127 (2%)
 Frame = +1

Query: 244 GHLPTPINVSITGSIPYTCPELKWYNFDVFPHKVKL---SNTGYTVLIGAKWKAERPYLE 414
           G   +PIN+ +  S+ Y    L  + F  +    KL   +N G+TV +     A    L 
Sbjct: 20  GSRQSPINI-VDASVQYNA-SLGTFTFTNYSDSSKLLLLNNPGHTVEVQL---ASGVTLS 74

Query: 415 GGPFQDKHIFSQIHFHWGADMMEGSDHTVDDRRYPGEMQVTFFRSEYMTQEEALRHPDGV 594
           GG     +     HFHWG     GS+H +  R++P EM +   ++  M    A + P G+
Sbjct: 75  GGGLLSTYSAVAFHFHWGNTSQNGSEHQLGGRQFPMEMHIVHTKNG-MNLTAAKQDPTGI 133

Query: 595 VMICYLI 615
            ++ + I
Sbjct: 134 AVLGFFI 140


>UniRef50_Q4SWK8 Cluster: Chromosome undetermined SCAF13612, whole
           genome shotgun sequence; n=1; Tetraodon
           nigroviridis|Rep: Chromosome undetermined SCAF13612,
           whole genome shotgun sequence - Tetraodon nigroviridis
           (Green puffer)
          Length = 186

 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 30/112 (26%), Positives = 49/112 (43%), Gaps = 1/112 (0%)
 Frame = +1

Query: 196 PLYGTLQWIYYWSDFEGHLPTPINVSITGSIPYTCPELKWYNFDVFPHKVK-LSNTGYTV 372
           P  G  +W   +   +G   +PIN+ +     Y  P LK           K + N G++ 
Sbjct: 9   PTNGPDKWAKDFPLADGPRQSPINI-VPAEAQYD-PSLKGLKLKYDQSNAKGILNNGHSF 66

Query: 373 LIGAKWKAERPYLEGGPFQDKHIFSQIHFHWGADMMEGSDHTVDDRRYPGEM 528
            +      +   L GGP    +   Q HFHWG     GS+HT+++ ++P E+
Sbjct: 67  QVDFVDDTDSSTLTGGPITGTYRLKQFHFHWGGSDDRGSEHTINNVKFPCEV 118


>UniRef50_Q7LZP1 Cluster: Carbonate dehydratase; n=1; Galeocerdo
           cuvier|Rep: Carbonate dehydratase - Galeocerdo cuvier
           (Tiger shark)
          Length = 200

 Score = 49.6 bits (113), Expect = 7e-05
 Identities = 26/74 (35%), Positives = 38/74 (51%)
 Frame = +1

Query: 409 LEGGPFQDKHIFSQIHFHWGADMMEGSDHTVDDRRYPGEMQVTFFRSEYMTQEEALRHPD 588
           L GGP   +    Q HFHWGA    GS+H +D + Y  E+ +     +Y    EAL+ PD
Sbjct: 31  LTGGPLCGR----QFHFHWGASDTHGSEHILDGKTYAAELHLV--HEKYSDFAEALKAPD 84

Query: 589 GVVMICYLIKVVRS 630
           G+ +   ++ V  S
Sbjct: 85  GLAVXGVMLXVCDS 98


>UniRef50_Q1ECZ8 Cluster: Zgc:158584; n=10; Danio rerio|Rep:
           Zgc:158584 - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 336

 Score = 49.2 bits (112), Expect = 9e-05
 Identities = 28/107 (26%), Positives = 52/107 (48%), Gaps = 3/107 (2%)
 Frame = +1

Query: 244 GHLPTPINVSITGSI--PYTCPELKWYNFDVFPHKVKLSNTGYTVLIGAKWKAERPYLEG 417
           G   +PIN+ +T  +       +  +  FD     + ++N+G +V++      E   ++G
Sbjct: 60  GSSQSPINI-VTAQVLENSNLTQFNFTGFDANTTFISMANSGISVVVTLD--EEIMSVQG 116

Query: 418 GPFQDKHIFSQIHFHWG-ADMMEGSDHTVDDRRYPGEMQVTFFRSEY 555
           G     ++  Q H HWG +    GS+HTVD ++Y  E+ +    S+Y
Sbjct: 117 GDLPGLYVSKQFHLHWGNSSSFPGSEHTVDGKQYAMELHIVNVHSKY 163


>UniRef50_Q18932 Cluster: Putative carbonic anhydrase-like protein 2
           precursor; n=2; Caenorhabditis|Rep: Putative carbonic
           anhydrase-like protein 2 precursor - Caenorhabditis
           elegans
          Length = 337

 Score = 49.2 bits (112), Expect = 9e-05
 Identities = 39/137 (28%), Positives = 66/137 (48%), Gaps = 6/137 (4%)
 Frame = +1

Query: 244 GHLPTPINVSITGSIPYTCPELKWYNFDVFPHKVKLSNTGYTVLIGAKWKAERPYLE--G 417
           G + +P+N+     + Y  P L   N +    +    NTG   ++  K    RP +   G
Sbjct: 33  GQMQSPVNID-PSQLLYD-PHLMPINIEGNIVEAVFENTGQLPVVTVKDLPNRPTINITG 90

Query: 418 GPFQD-KHIFSQIHFHWG-ADMME-GSDHTVDDRRYPGEMQVTFFRSE-YMTQEEALRHP 585
           GP    ++   QI  H+G AD  E GS+HTVD  R+P E+Q+  + S  Y     A+  P
Sbjct: 91  GPTMPYRYKLHQISVHFGRADEGEKGSEHTVDRVRFPAEIQLLAYNSALYPNFSVAMTSP 150

Query: 586 DGVVMICYLIKVVRSES 636
            G++ +  ++ + ++ S
Sbjct: 151 RGLLAVSVIVDIGKTTS 167


>UniRef50_Q7SYW3 Cluster: MGC64443 protein; n=3; Xenopus|Rep:
           MGC64443 protein - Xenopus laevis (African clawed frog)
          Length = 312

 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 25/98 (25%), Positives = 48/98 (48%), Gaps = 1/98 (1%)
 Frame = +1

Query: 256 TPINVSITGSI-PYTCPELKWYNFDVFPHKVKLSNTGYTVLIGAKWKAERPYLEGGPFQD 432
           +PIN+    ++   +  E    ++ V   ++ ++N G++  +      E   + GG    
Sbjct: 60  SPINILTKKAVFMESLKEFDLKSYGVSIRQLNVTNNGHSAQVDLPPGIE---ISGGGLSG 116

Query: 433 KHIFSQIHFHWGADMMEGSDHTVDDRRYPGEMQVTFFR 546
            +   Q HFHWG++   GS+HT+D  +YP E+ +   R
Sbjct: 117 TYDAIQFHFHWGSEEFPGSEHTIDGEKYPMELHIVHRR 154


>UniRef50_Q4SZW1 Cluster: Chromosome undetermined SCAF11462, whole
           genome shotgun sequence; n=8; Euteleostomi|Rep:
           Chromosome undetermined SCAF11462, whole genome shotgun
           sequence - Tetraodon nigroviridis (Green puffer)
          Length = 526

 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 32/105 (30%), Positives = 52/105 (49%), Gaps = 3/105 (2%)
 Frame = +1

Query: 304 ELKWYNFDVFPHKVKLSNTGYTVLIGAKWKAERPYLEGGPFQDKHIFSQIHFHWGADMME 483
           +L+   +D       ++N G+TV I           EG P   K+   Q+H HWG   +E
Sbjct: 68  QLELSGYDAQQGTFLMTNNGHTVQIDLP--PTMVITEGLP--GKYTAVQMHLHWGGWDLE 123

Query: 484 --GSDHTVDDRRYPGEMQVTFFRSE-YMTQEEALRHPDGVVMICY 609
             G++HT+D  RY  E+ V  + S+ Y +  EA   PDG+ ++ +
Sbjct: 124 ASGAEHTIDGVRYMAELHVVHYNSDKYKSFIEARDKPDGLAVLAF 168


>UniRef50_P23470 Cluster: Receptor-type tyrosine-protein phosphatase
           gamma precursor; n=33; Euteleostomi|Rep: Receptor-type
           tyrosine-protein phosphatase gamma precursor - Homo
           sapiens (Human)
          Length = 1445

 Score = 48.8 bits (111), Expect = 1e-04
 Identities = 33/120 (27%), Positives = 57/120 (47%), Gaps = 3/120 (2%)
 Frame = +1

Query: 202 YGTLQWIYYWSDFEGHLPTPINV-SITGSIPYTCPELKWYNFD-VFPHKVKLSNTGYTVL 375
           YG   W+       G   +PI++      +     EL+   FD    +K  + NTG TV 
Sbjct: 66  YGPEHWVTSSVSCGGRHQSPIDILDQYARVGEEYQELQLDGFDNESSNKTWMKNTGKTVA 125

Query: 376 IGAKWKAERPYLEGGPFQDKHIFSQIHFHWG-ADMMEGSDHTVDDRRYPGEMQVTFFRSE 552
           I  K   +  ++ G     +    ++ FHWG ++   GS+H+++ RR+P EMQ+ F+  +
Sbjct: 126 ILLK---DDYFVSGAGLPGRFKAEKVEFHWGHSNGSAGSEHSINGRRFPVEMQIFFYNPD 182


>UniRef50_UPI0000F2BDC6 Cluster: PREDICTED: similar to Carbonic
           anhydrase 4 precursor (Carbonic anhydrase IV) (Carbonate
           dehydratase IV) (CA-IV), partial; n=1; Monodelphis
           domestica|Rep: PREDICTED: similar to Carbonic anhydrase
           4 precursor (Carbonic anhydrase IV) (Carbonate
           dehydratase IV) (CA-IV), partial - Monodelphis domestica
          Length = 277

 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 30/113 (26%), Positives = 54/113 (47%), Gaps = 2/113 (1%)
 Frame = +1

Query: 256 TPINVSITGSIP--YTCPELKWYNFDVFPHKVKLSNTGYTVLIGAKWKAERPYLEGGPFQ 429
           +PIN+ IT  I   Y+  + K+  +D+   +  + N GYT+ +     A+   + GG   
Sbjct: 14  SPINI-ITKQIKLNYSLVDFKFSGYDL-KQETFIKNNGYTIKMPLPDSAK---ISGGGLS 68

Query: 430 DKHIFSQIHFHWGADMMEGSDHTVDDRRYPGEMQVTFFRSEYMTQEEALRHPD 588
             +   + H HW   + +GS+HT+D + +  EM V   + ++     AL   D
Sbjct: 69  GTYKGVESHLHWSDSVDKGSEHTIDGKAFAMEMHVIHMKEKFANLSMALASSD 121


>UniRef50_UPI000065D5A1 Cluster: Carbonic anhydrase 6 precursor (EC
           4.2.1.1) (Carbonic anhydrase VI) (Carbonate dehydratase
           VI) (CA-VI) (Secreted carbonic anhydrase) (Salivary
           carbonic anhydrase).; n=3; Clupeocephala|Rep: Carbonic
           anhydrase 6 precursor (EC 4.2.1.1) (Carbonic anhydrase
           VI) (Carbonate dehydratase VI) (CA-VI) (Secreted
           carbonic anhydrase) (Salivary carbonic anhydrase). -
           Takifugu rubripes
          Length = 528

 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 30/90 (33%), Positives = 47/90 (52%), Gaps = 3/90 (3%)
 Frame = +1

Query: 349 LSNTGYTVLIGAKWKAERPYLEGGPFQDKHIFSQIHFHWGADMME--GSDHTVDDRRYPG 522
           ++N G+TV I           EG P   K+   Q+H HWG   +E  G++HT+D  RY  
Sbjct: 84  MTNNGHTVQIDLP--PTMMITEGLP--GKYTAVQMHLHWGGWDLEASGAEHTIDGIRYMA 139

Query: 523 EMQVTFFRSE-YMTQEEALRHPDGVVMICY 609
           E+ V  + S+ Y +  EA   PDG+ ++ +
Sbjct: 140 ELHVVHYNSDKYKSFIEARDKPDGLAVLAF 169


>UniRef50_Q20781 Cluster: Putative carbonic anhydrase-like protein 1
           precursor; n=2; Caenorhabditis|Rep: Putative carbonic
           anhydrase-like protein 1 precursor - Caenorhabditis
           elegans
          Length = 365

 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 25/91 (27%), Positives = 48/91 (52%), Gaps = 4/91 (4%)
 Frame = +1

Query: 355 NTGYTVLIGAKWKAERPYLE--GGPFQD-KHIFSQIHFHWGADMMEGSDHTVDDRRYPGE 525
           NTG  V +   + +++P +    GP    ++   +I FH G     GS+HT++ RR+P E
Sbjct: 153 NTGQMVRVRIGYSSKKPSVNITSGPLYGYRYRVQRIDFHMGRKNENGSEHTINGRRFPME 212

Query: 526 MQVTFFRSE-YMTQEEALRHPDGVVMICYLI 615
           +Q+  + ++ Y     A + P G+ ++  L+
Sbjct: 213 VQLVAYNTDLYPNFTSASKSPHGIAILSVLV 243


>UniRef50_UPI000065EB91 Cluster: Homolog of Homo sapiens "Splice
           Isoform Long of Receptor-type tyrosine-protein
           phosphatase zeta precursor; n=1; Takifugu rubripes|Rep:
           Homolog of Homo sapiens "Splice Isoform Long of
           Receptor-type tyrosine-protein phosphatase zeta
           precursor - Takifugu rubripes
          Length = 1506

 Score = 46.8 bits (106), Expect = 5e-04
 Identities = 24/80 (30%), Positives = 43/80 (53%), Gaps = 3/80 (3%)
 Frame = +1

Query: 406 YLEGGPFQDKHIFSQIHFHWGA--DMMEGSDHTVDDRRYPGEMQVTFFRSEYM-TQEEAL 576
           Y+ GG  + K    +I FHWG      EGS+H+VD  +YP EMQ+  ++  +  + +E++
Sbjct: 102 YIGGGSLRSKFKVGRITFHWGRCNASTEGSEHSVDGVKYPLEMQIYCYQPHHFHSLDESI 161

Query: 577 RHPDGVVMICYLIKVVRSES 636
           +    +V +  L +    E+
Sbjct: 162 KAGGRIVALAVLFETSSQEN 181


>UniRef50_Q9ULX7 Cluster: Carbonic anhydrase 14 precursor; n=17;
           Tetrapoda|Rep: Carbonic anhydrase 14 precursor - Homo
           sapiens (Human)
          Length = 337

 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 37/145 (25%), Positives = 68/145 (46%), Gaps = 5/145 (3%)
 Frame = +1

Query: 202 YGTLQWIYYWSDFEGHLPTPINVSITGSIPYT--CPELKWYNFDV-FPHKVKLSNTGYTV 372
           +G   W   + +   +  +PI++  T S+ +    P L+ + +D      + L N G+TV
Sbjct: 28  HGQDHWPASYPECGNNAQSPIDIQ-TDSVTFDPDLPALQPHGYDQPGTEPLDLHNNGHTV 86

Query: 373 LIGAKWKAERPYLEGGPFQDKHIFSQIHFHWG-ADMMEGSDHTVDDRRYPGEMQVTFFRS 549
            +         YL G P   K++ +Q+H HWG      GS+H ++      E+ +  + S
Sbjct: 87  QLSLP---STLYLGGLP--RKYVAAQLHLHWGQKGSPGGSEHQINSEATFAELHIVHYDS 141

Query: 550 E-YMTQEEALRHPDGVVMICYLIKV 621
           + Y +  EA   P G+ ++  LI+V
Sbjct: 142 DSYDSLSEAAERPQGLAVLGILIEV 166


>UniRef50_A7S762 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 251

 Score = 46.0 bits (104), Expect = 9e-04
 Identities = 32/141 (22%), Positives = 64/141 (45%), Gaps = 2/141 (1%)
 Frame = +1

Query: 205 GTLQWIYYWSDFEGHLPTPINVSITGSIPYTCPELKWYNFDVFPHKVKLSNTGYTVLIGA 384
           G L+W   +   E    +PI++        +     W  ++   +   L+N G T+ +  
Sbjct: 1   GPLRWHKCYIGAEPGHQSPIDIVTKDVTQDSSLGSLWNTYEPVANST-LTNDGRTLQL-- 57

Query: 385 KWKAERPYLEGGPFQDKHIFSQIHFHWGA-DMMEGSDHTVDDRRYPGEMQVTFF-RSEYM 558
            +      L GGP  D++  + I FHW A +   GS+H +D + +  E+Q+  + +++Y 
Sbjct: 58  TFANNNNVLSGGPLTDEYQLAMIKFHWAATEESAGSEHMIDSQGHAIEVQLVHWNKTKYR 117

Query: 559 TQEEALRHPDGVVMICYLIKV 621
              EA+    G+ ++    +V
Sbjct: 118 NIGEAITGEQGICILAVFFQV 138


>UniRef50_A6YCJ0 Cluster: Astrosclerin-2; n=3; Astrosclera
           willeyana|Rep: Astrosclerin-2 - Astrosclera willeyana
          Length = 292

 Score = 46.0 bits (104), Expect = 9e-04
 Identities = 16/28 (57%), Positives = 20/28 (71%)
 Frame = +1

Query: 448 QIHFHWGADMMEGSDHTVDDRRYPGEMQ 531
           Q HFHWG D  EGS+H +DD +Y  E+Q
Sbjct: 108 QFHFHWGRDSSEGSEHQIDDEQYSAEIQ 135


>UniRef50_Q3B7E6 Cluster: Zgc:123188; n=2; Danio rerio|Rep:
           Zgc:123188 - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 259

 Score = 45.6 bits (103), Expect = 0.001
 Identities = 37/145 (25%), Positives = 67/145 (46%), Gaps = 7/145 (4%)
 Frame = +1

Query: 205 GTLQWIYYWSDFEGHLPTPINVSITGSI--PYTCP-ELKWYNFDVFPHKVKLSNTGYTVL 375
           G  +WI ++ +  G   +P+NV  + ++  P   P +   YN         LSN G+TV 
Sbjct: 33  GQPEWIEFFPECGGFNQSPVNVDTSQTLHDPTLIPVQPMGYN-QPGRRPFILSNNGHTV- 90

Query: 376 IGAKWKAERPYLEG-GPFQDKHIFSQIHFHWG--ADMMEGSDHTVDDRRYPGEMQVTFFR 546
                +   P+  G G     +   Q+H HWG    +  GS+HT++ +    E+ +  + 
Sbjct: 91  -----QMTLPHWMGVGGLPSHYSAVQLHLHWGNGVGIATGSEHTINGQSTSAELHIVHYN 145

Query: 547 SE-YMTQEEALRHPDGVVMICYLIK 618
           +E Y    EA+   +G+ ++  LI+
Sbjct: 146 TEVYANLPEAMMQKNGLAVLGILIE 170


>UniRef50_A3KNU9 Cluster: Si:ch211-258f14.6 protein; n=5; Danio
           rerio|Rep: Si:ch211-258f14.6 protein - Danio rerio
           (Zebrafish) (Brachydanio rerio)
          Length = 515

 Score = 45.6 bits (103), Expect = 0.001
 Identities = 26/93 (27%), Positives = 48/93 (51%), Gaps = 3/93 (3%)
 Frame = +1

Query: 349 LSNTGYTVLIGAKWKAERPYLEGGPFQDKHIFSQIHFHWGA--DMMEGSDHTVDDRRYPG 522
           ++N G TV+IG        ++ GG  + +    +I FHWG      +GS+H+++  R+P 
Sbjct: 112 ITNDGKTVVIGLN---SEYFISGGGLRSRFKVGRITFHWGRCNATSDGSEHSLNGNRFPL 168

Query: 523 EMQVTFFRS-EYMTQEEALRHPDGVVMICYLIK 618
           EMQ+  F   E+ + +EA+     +  +  L +
Sbjct: 169 EMQIYCFDDLEFESIDEAMSSGGKIAAVAVLFE 201


>UniRef50_UPI0000E1EBDB Cluster: PREDICTED: carbonic anhydrase XIV
           isoform 4; n=1; Pan troglodytes|Rep: PREDICTED: carbonic
           anhydrase XIV isoform 4 - Pan troglodytes
          Length = 313

 Score = 45.2 bits (102), Expect = 0.001
 Identities = 36/144 (25%), Positives = 67/144 (46%), Gaps = 5/144 (3%)
 Frame = +1

Query: 202 YGTLQWIYYWSDFEGHLPTPINVSITGSIPYT--CPELKWYNFDV-FPHKVKLSNTGYTV 372
           +G   W   + +   +  +PI++  T S+ +    P L+ + +D      + L N G+TV
Sbjct: 28  HGQDHWPASYPECGNNAQSPIDIQ-TDSVTFDPDLPALQPHGYDQPGTEPLDLHNNGHTV 86

Query: 373 LIGAKWKAERPYLEGGPFQDKHIFSQIHFHWG-ADMMEGSDHTVDDRRYPGEMQVTFFRS 549
            +         YL G P   K++ +Q+H HWG      GS+H ++      E+ +  + S
Sbjct: 87  QLSLP---STLYLGGLP--RKYVAAQLHLHWGQKGSPGGSEHQINSEATVAELHIVHYDS 141

Query: 550 E-YMTQEEALRHPDGVVMICYLIK 618
           + Y +  EA   P G+ ++  LI+
Sbjct: 142 DSYDSLSEAAEKPQGLAVLGILIE 165


>UniRef50_UPI000069EFAD Cluster: UPI000069EFAD related cluster; n=1;
           Xenopus tropicalis|Rep: UPI000069EFAD UniRef100 entry -
           Xenopus tropicalis
          Length = 261

 Score = 44.8 bits (101), Expect = 0.002
 Identities = 25/94 (26%), Positives = 46/94 (48%), Gaps = 2/94 (2%)
 Frame = +1

Query: 346 KLSNTGYTVLIGAKWKAERPYLEGGPFQDKHIFSQIHFHWGAD--MMEGSDHTVDDRRYP 519
           +L+N G++V +    K     L G    D +  +  H H+G       GS+H ++   +P
Sbjct: 59  ELTNNGHSVEVTLTSKYT---LSGAGLTDAYTLAGFHIHFGNSNPTFGGSEHQINGNAFP 115

Query: 520 GEMQVTFFRSEYMTQEEALRHPDGVVMICYLIKV 621
            E+   F+ S+Y+   EA +  DG+ ++  L +V
Sbjct: 116 LEVHFVFYNSKYIDLTEAKQQSDGLAVVGVLFQV 149


>UniRef50_UPI0000ECAF42 Cluster: Carbonic anhydrase 12 precursor (EC
           4.2.1.1) (Carbonic anhydrase XII) (Carbonate dehydratase
           XII) (CA-XII) (Tumor antigen HOM-RCC-3.1.3).; n=2;
           Amniota|Rep: Carbonic anhydrase 12 precursor (EC
           4.2.1.1) (Carbonic anhydrase XII) (Carbonate dehydratase
           XII) (CA-XII) (Tumor antigen HOM-RCC-3.1.3). - Gallus
           gallus
          Length = 199

 Score = 44.8 bits (101), Expect = 0.002
 Identities = 25/93 (26%), Positives = 50/93 (53%), Gaps = 2/93 (2%)
 Frame = +1

Query: 349 LSNTGYTVLIGAKWKAERPYLEGGPFQDKHIFSQIHFHWG-ADMMEGSDHTVDDRRYPGE 525
           L+N G++V +     +   ++   PF+  +  SQ+H HWG  +  EGS+HTV  + +  E
Sbjct: 91  LTNNGHSVKMHL---SPTMHIRNLPFE--YTASQLHLHWGNRNKSEGSEHTVSGKHFAAE 145

Query: 526 MQVTFFRSE-YMTQEEALRHPDGVVMICYLIKV 621
           + +  + SE Y     A+   +G+ ++  L+++
Sbjct: 146 VHIVHYNSEKYPDIAAAMDKANGLAVLAILLEI 178


>UniRef50_Q4T8T1 Cluster: Chromosome undetermined SCAF7729, whole
           genome shotgun sequence; n=1; Tetraodon
           nigroviridis|Rep: Chromosome undetermined SCAF7729,
           whole genome shotgun sequence - Tetraodon nigroviridis
           (Green puffer)
          Length = 331

 Score = 44.8 bits (101), Expect = 0.002
 Identities = 25/80 (31%), Positives = 39/80 (48%), Gaps = 2/80 (2%)
 Frame = +1

Query: 355 NTGYTVLIGAKWKAERPYLEGGPFQDKHIFS--QIHFHWGADMMEGSDHTVDDRRYPGEM 528
           N G+TV I  + K+    + GGP    H +   ++ FHWG +   GS+HTV+ + +P E 
Sbjct: 51  NDGHTVRILLRSKS---VVAGGPLPSGHEYELHEVRFHWGKENQRGSEHTVNFKAFPMES 107

Query: 529 QVTFFRSEYMTQEEALRHPD 588
           +    R        A+  PD
Sbjct: 108 KPVCSRGRTSGSTTAVAPPD 127


>UniRef50_A6QR78 Cluster: Carbonic anhydrase 1; n=2; Nematostella
           vectensis|Rep: Carbonic anhydrase 1 - Nematostella
           vectensis
          Length = 299

 Score = 44.4 bits (100), Expect = 0.003
 Identities = 36/144 (25%), Positives = 68/144 (47%), Gaps = 6/144 (4%)
 Frame = +1

Query: 205 GTLQWIYYWSDFEGHLPTPINVSITGSIPY----TCPELKWYNF-DVFPHKVKLSNTGYT 369
           G   W  ++    G + +PIN++ T    Y    T  ++K+ N  DV    + +++ G+ 
Sbjct: 40  GPSTWPNHFPHCGGKMQSPININ-TEEAKYDGSLTDLDIKYPNTTDV----LLVNHHGHA 94

Query: 370 VLIGAKWKAERPYLE-GGPFQDKHIFSQIHFHWGADMMEGSDHTVDDRRYPGEMQVTFFR 546
             I A   +  P++  G     ++  +Q HFH G+  ++GS+H +   +YP EM +  + 
Sbjct: 95  --IEADILSSEPFVATGADLSSRYRLAQFHFHVGSSDIQGSEHHIHGVKYPLEMHLVHYN 152

Query: 547 SEYMTQEEALRHPDGVVMICYLIK 618
            +Y     A    DG+ +I  L +
Sbjct: 153 DKYPNASSAQGLLDGLAVISVLFE 176


>UniRef50_A6QR75 Cluster: Carbonic anhydrase 1; n=1; Amphimedon
           queenslandica|Rep: Carbonic anhydrase 1 - Amphimedon
           queenslandica
          Length = 282

 Score = 44.0 bits (99), Expect = 0.003
 Identities = 35/104 (33%), Positives = 46/104 (44%), Gaps = 5/104 (4%)
 Frame = +1

Query: 244 GH-LPTPINV--SITGSIPYTCPELKWYNF-DVFPHKVKLSNTGYTVLIGAKWKAERPYL 411
           GH L +PIN+  S+  +   +   LK   + DV      L N G+T+           YL
Sbjct: 53  GHNLQSPINILSSLAANTDESVAPLKMCGWCDV--RSGTLKNNGHTLKFTPSQYGSDAYL 110

Query: 412 EGGPFQDKHIFSQIHFHWGADMME-GSDHTVDDRRYPGEMQVTF 540
                 +   F Q HFHWG    + GS+HTVD   Y GEM   F
Sbjct: 111 SSRN-HNSFKFLQFHFHWGPKNTKVGSEHTVDGGAYNGEMHFVF 153


>UniRef50_UPI0001555A70 Cluster: PREDICTED: hypothetical protein;
           n=1; Ornithorhynchus anatinus|Rep: PREDICTED:
           hypothetical protein - Ornithorhynchus anatinus
          Length = 422

 Score = 43.6 bits (98), Expect = 0.005
 Identities = 29/130 (22%), Positives = 60/130 (46%), Gaps = 4/130 (3%)
 Frame = +1

Query: 244 GHLPTPINVSITGSIP---YTCPELKWYNFDVFPHKVKLSNTGYTVLIGAKWKAERPYLE 414
           G   +P+ +    S+P   +   E+  Y     P  +K++N G++  +  +  A   +L 
Sbjct: 92  GRRQSPVALWADRSVPASHFKVLEMSGYENPTLP--IKVTNDGHSANVNLRPGA---WLS 146

Query: 415 GGPFQDKHIFSQIHFHWGADM-MEGSDHTVDDRRYPGEMQVTFFRSEYMTQEEALRHPDG 591
           GG     +     H HWG  +   G++H ++  R   E+ V   + + +   +A++  DG
Sbjct: 147 GGGLSGNYTAQSFHLHWGKGLNFPGAEHLLEGTRASMELHVVHTK-DGLPMNKAVKLKDG 205

Query: 592 VVMICYLIKV 621
           VV++ ++  V
Sbjct: 206 VVVLAFMTNV 215


>UniRef50_UPI0000F21610 Cluster: PREDICTED: similar to protein
           tyrosine phosphatase, receptor-type, Z polypeptide 1,;
           n=2; Danio rerio|Rep: PREDICTED: similar to protein
           tyrosine phosphatase, receptor-type, Z polypeptide 1, -
           Danio rerio
          Length = 1814

 Score = 43.6 bits (98), Expect = 0.005
 Identities = 26/93 (27%), Positives = 45/93 (48%), Gaps = 3/93 (3%)
 Frame = +1

Query: 349 LSNTGYTVLIGAKWKAERPYLEGGPFQDKHIFSQIHFHWGA--DMMEGSDHTVDDRRYPG 522
           + N G TV I    +    Y+ GG  + K    +I FHWG      +GS+H ++  +YP 
Sbjct: 84  VKNDGKTVAIDVGGEF---YVSGGGLRSKFKVGRISFHWGLCNASSDGSEHGLNGEKYPL 140

Query: 523 EMQVTFFRSEYMTQ-EEALRHPDGVVMICYLIK 618
           EMQ+  + ++  +  +EA R    +  +  L +
Sbjct: 141 EMQIYCYEADVFSDLDEAFREGGKITALAVLFE 173


>UniRef50_UPI00005A2CD6 Cluster: PREDICTED: similar to Receptor-type
           tyrosine-protein phosphatase zeta precursor
           (R-PTP-zeta); n=1; Canis lupus familiaris|Rep:
           PREDICTED: similar to Receptor-type tyrosine-protein
           phosphatase zeta precursor (R-PTP-zeta) - Canis
           familiaris
          Length = 1926

 Score = 43.2 bits (97), Expect = 0.006
 Identities = 31/99 (31%), Positives = 52/99 (52%), Gaps = 3/99 (3%)
 Frame = +1

Query: 349 LSNTGYTVLIGAKWKAERPYLEGGPFQDKHIFSQIHFHWGADMM--EGSDHTVDDRRYPG 522
           + NTG TV I          L GG  +     S+I FHWG   M  EGS+H+++ +++P 
Sbjct: 112 IHNTGKTVEINL---TNDYRLSGGVSEMVFKASKISFHWGKCNMSSEGSEHSLEGQKFPL 168

Query: 523 EMQVTFFRSE-YMTQEEALRHPDGVVMICYLIKVVRSES 636
           EMQ+  F ++ + + EEA++    +  +  L +V   E+
Sbjct: 169 EMQIYCFDADRFSSFEEAVKAKGKLRALSVLFEVGMEEN 207


>UniRef50_UPI00006C1B11 Cluster: PREDICTED: similar to carbonic
           anhydrase 15; n=2; Homo sapiens|Rep: PREDICTED: similar
           to carbonic anhydrase 15 - Homo sapiens
          Length = 362

 Score = 42.7 bits (96), Expect = 0.008
 Identities = 20/52 (38%), Positives = 30/52 (57%), Gaps = 3/52 (5%)
 Frame = +1

Query: 448 QIHFH---WGADMMEGSDHTVDDRRYPGEMQVTFFRSEYMTQEEALRHPDGV 594
           Q+HF+   WG      S+H++D +R   EM V    ++Y + EEA RH DG+
Sbjct: 172 QLHFNCRRWGGPRRADSEHSLDRQRQAMEMHVVHSNTKYQSMEEAPRHGDGL 223


>UniRef50_O43570 Cluster: Carbonic anhydrase 12 precursor; n=37;
           Amniota|Rep: Carbonic anhydrase 12 precursor - Homo
           sapiens (Human)
          Length = 354

 Score = 42.7 bits (96), Expect = 0.008
 Identities = 33/144 (22%), Positives = 65/144 (45%), Gaps = 5/144 (3%)
 Frame = +1

Query: 205 GTLQWIYYWSDFEGHLPTPINVS---ITGSIPYTCPELKWYNFDVFPHKVKLSNTGYTVL 375
           G   W   +    G L +PI++    +      T  E + YN      +  L+N G++V 
Sbjct: 39  GENSWSKKYPSCGGLLQSPIDLHSDILQYDASLTPLEFQGYNLSA-NKQFLLTNNGHSVK 97

Query: 376 IGAKWKAERPYLEGGPFQDKHIFSQIHFHWG-ADMMEGSDHTVDDRRYPGEMQVTFFRSE 552
           +         +++G   Q ++  +Q+H HWG  +   GS+HTV  + +  E+ +  + S+
Sbjct: 98  LNLP---SDMHIQG--LQSRYSATQLHLHWGNPNDPHGSEHTVSGQHFAAELHIVHYNSD 152

Query: 553 -YMTQEEALRHPDGVVMICYLIKV 621
            Y     A    +G+ ++  LI++
Sbjct: 153 LYPDASTASNKSEGLAVLAVLIEM 176


>UniRef50_UPI00015A4051 Cluster: hypothetical protein LOC406461;
           n=1; Danio rerio|Rep: hypothetical protein LOC406461 -
           Danio rerio
          Length = 292

 Score = 42.3 bits (95), Expect = 0.011
 Identities = 20/63 (31%), Positives = 34/63 (53%), Gaps = 1/63 (1%)
 Frame = +1

Query: 349 LSNTGYTVLIGAKWKAERPYLEGGPFQDKHIFSQIHFHWG-ADMMEGSDHTVDDRRYPGE 525
           + NTG ++ +    K  R  + GG    +   ++ H HWG    M GS+HTV+ +R+P E
Sbjct: 69  IKNTGTSIQVTLDPKKMR--VAGGNLPGRFASTEFHLHWGNGSAMPGSEHTVNGKRFPME 126

Query: 526 MQV 534
           + +
Sbjct: 127 LHI 129


>UniRef50_Q7SZR2 Cluster: Zgc:77106; n=7; Clupeocephala|Rep:
           Zgc:77106 - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 305

 Score = 42.3 bits (95), Expect = 0.011
 Identities = 20/63 (31%), Positives = 34/63 (53%), Gaps = 1/63 (1%)
 Frame = +1

Query: 349 LSNTGYTVLIGAKWKAERPYLEGGPFQDKHIFSQIHFHWG-ADMMEGSDHTVDDRRYPGE 525
           + NTG ++ +    K  R  + GG    +   ++ H HWG    M GS+HTV+ +R+P E
Sbjct: 69  IKNTGTSIQVTLDPKKMR--VAGGNLPGRFASTEFHLHWGNGSAMPGSEHTVNGKRFPME 126

Query: 526 MQV 534
           + +
Sbjct: 127 LHI 129


>UniRef50_Q28ZR2 Cluster: GA13586-PA; n=1; Drosophila
           pseudoobscura|Rep: GA13586-PA - Drosophila pseudoobscura
           (Fruit fly)
          Length = 286

 Score = 41.5 bits (93), Expect = 0.018
 Identities = 29/96 (30%), Positives = 45/96 (46%), Gaps = 2/96 (2%)
 Frame = +1

Query: 253 PTPINVSITGSIPYTCPEL-KWYNFDVFPHKVKLSNTGYTVLIGAKWKAER-PYLEGGPF 426
           PTPIN+  + +       L  W ++D  P  + L N G TV++    +    P L GG  
Sbjct: 64  PTPINIVRSMARKMELGSLLDWKHYDDMPLAMLLENNGSTVILRICCEPYLVPQLSGGDL 123

Query: 427 QDKHIFSQIHFHWGADMMEGSDHTVDDRRYPGEMQV 534
             ++ F +  F WG    E   H++D  ++  EMQV
Sbjct: 124 PGEYHFVEACFKWGPLRAE---HSIDSMKFSLEMQV 156


>UniRef50_Q62656 Cluster: Receptor-type tyrosine-protein phosphatase
           zeta precursor; n=13; Amniota|Rep: Receptor-type
           tyrosine-protein phosphatase zeta precursor - Rattus
           norvegicus (Rat)
          Length = 2316

 Score = 41.5 bits (93), Expect = 0.018
 Identities = 26/80 (32%), Positives = 45/80 (56%), Gaps = 3/80 (3%)
 Frame = +1

Query: 349 LSNTGYTVLIGAKWKAERPYLEGGPFQDKHIFSQIHFHWGADMM--EGSDHTVDDRRYPG 522
           + NTG TV I         YL GG  +     S++ FHWG   +  EGS+H+++ +++P 
Sbjct: 95  IHNTGKTVEINL---TNDYYLSGGLSEKVFKASKMTFHWGKCNVSSEGSEHSLEGQKFPL 151

Query: 523 EMQVTFFRSE-YMTQEEALR 579
           EMQ+  F ++ + + EE ++
Sbjct: 152 EMQIYCFDADRFSSFEETVK 171


>UniRef50_UPI0000E249D6 Cluster: PREDICTED: carbonic anhydrase IV
           isoform 2; n=1; Pan troglodytes|Rep: PREDICTED: carbonic
           anhydrase IV isoform 2 - Pan troglodytes
          Length = 336

 Score = 41.1 bits (92), Expect = 0.024
 Identities = 22/95 (23%), Positives = 49/95 (51%), Gaps = 2/95 (2%)
 Frame = +1

Query: 349 LSNTGYTVLIGAKWKAERPYLEGGPFQDKHIFSQIHFHWGADMMEGSDHTVDDRRYPGEM 528
           + N G++V++  + KA    + GG     +   Q+H HW     +GS+H++D   +  EM
Sbjct: 83  VQNNGHSVMMLLENKAS---ISGGGLPAPYQAKQLHLHWSDLPYKGSEHSLDGEHFAMEM 139

Query: 529 QVTFFRSEYMTQ--EEALRHPDGVVMICYLIKVVR 627
            +   + +  ++  +EA    D + ++ +L+++ R
Sbjct: 140 HIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEIGR 174


>UniRef50_P23471-2 Cluster: Isoform Short of P23471 ; n=6;
           Tetrapoda|Rep: Isoform Short of P23471 - Homo sapiens
           (Human)
          Length = 1454

 Score = 40.3 bits (90), Expect = 0.042
 Identities = 29/99 (29%), Positives = 52/99 (52%), Gaps = 3/99 (3%)
 Frame = +1

Query: 349 LSNTGYTVLIGAKWKAERPYLEGGPFQDKHIFSQIHFHWGADMM--EGSDHTVDDRRYPG 522
           + NTG TV I          + GG  +     S+I FHWG   M  +GS+H+++ +++P 
Sbjct: 95  IHNTGKTVEINL---TNDYRVSGGVSEMVFKASKITFHWGKCNMSSDGSEHSLEGQKFPL 151

Query: 523 EMQVTFFRSE-YMTQEEALRHPDGVVMICYLIKVVRSES 636
           EMQ+  F ++ + + EEA++    +  +  L +V   E+
Sbjct: 152 EMQIYCFDADRFSSFEEAVKGKGKLRALSILFEVGTEEN 190


>UniRef50_Q4SE53 Cluster: Chromosome undetermined SCAF14625, whole
           genome shotgun sequence; n=1; Tetraodon
           nigroviridis|Rep: Chromosome undetermined SCAF14625,
           whole genome shotgun sequence - Tetraodon nigroviridis
           (Green puffer)
          Length = 1553

 Score = 40.3 bits (90), Expect = 0.042
 Identities = 22/77 (28%), Positives = 41/77 (53%), Gaps = 5/77 (6%)
 Frame = +1

Query: 406 YLEGGPFQDKHIFSQIHFHWGA--DMMEGSDHTVDDRRYPGE--MQVTFFRSE-YMTQEE 570
           Y+ GG  + K    +I FHWG      +GS+H+VD  RYP E  MQ+  ++ +   + +E
Sbjct: 104 YVSGGALRSKFKVGRITFHWGRCNASTDGSEHSVDGARYPLEVGMQIYCYQPQSSQSLDE 163

Query: 571 ALRHPDGVVMICYLIKV 621
           +++    +  +  L ++
Sbjct: 164 SIKAGGRIAALAVLFEI 180


>UniRef50_P23471 Cluster: Receptor-type tyrosine-protein phosphatase
           zeta precursor; n=10; Euarchontoglires|Rep:
           Receptor-type tyrosine-protein phosphatase zeta
           precursor - Homo sapiens (Human)
          Length = 2314

 Score = 40.3 bits (90), Expect = 0.042
 Identities = 29/99 (29%), Positives = 52/99 (52%), Gaps = 3/99 (3%)
 Frame = +1

Query: 349 LSNTGYTVLIGAKWKAERPYLEGGPFQDKHIFSQIHFHWGADMM--EGSDHTVDDRRYPG 522
           + NTG TV I          + GG  +     S+I FHWG   M  +GS+H+++ +++P 
Sbjct: 95  IHNTGKTVEINL---TNDYRVSGGVSEMVFKASKITFHWGKCNMSSDGSEHSLEGQKFPL 151

Query: 523 EMQVTFFRSE-YMTQEEALRHPDGVVMICYLIKVVRSES 636
           EMQ+  F ++ + + EEA++    +  +  L +V   E+
Sbjct: 152 EMQIYCFDADRFSSFEEAVKGKGKLRALSILFEVGTEEN 190


>UniRef50_O75493 Cluster: Carbonic anhydrase-related protein 11
           precursor; n=49; Euteleostomi|Rep: Carbonic
           anhydrase-related protein 11 precursor - Homo sapiens
           (Human)
          Length = 328

 Score = 40.3 bits (90), Expect = 0.042
 Identities = 23/84 (27%), Positives = 41/84 (48%), Gaps = 3/84 (3%)
 Frame = +1

Query: 394 AERPYLE--GGPFQDKHIFSQIHFHWGADMMEGSDHTVDDRRYPGEMQVTFFRSE-YMTQ 564
           A RP +   GGP    H  S++   +GA    GS+H ++ + +  E+Q+  F  E Y   
Sbjct: 112 APRPVVNVSGGPLLYSHRLSELRLLFGARDGAGSEHQINHQGFSAEVQLIHFNQELYGNF 171

Query: 565 EEALRHPDGVVMICYLIKVVRSES 636
             A R P+G+ ++   + V  + +
Sbjct: 172 SAASRGPNGLAILSLFVNVASTSN 195


>UniRef50_UPI0000ECD15B Cluster: Carbonic anhydrase 1 (EC 4.2.1.1)
           (Carbonic anhydrase I) (Carbonate dehydratase I)
           (CA-I).; n=1; Gallus gallus|Rep: Carbonic anhydrase 1
           (EC 4.2.1.1) (Carbonic anhydrase I) (Carbonate
           dehydratase I) (CA-I). - Gallus gallus
          Length = 183

 Score = 39.5 bits (88), Expect = 0.074
 Identities = 18/69 (26%), Positives = 36/69 (52%)
 Frame = +1

Query: 346 KLSNTGYTVLIGAKWKAERPYLEGGPFQDKHIFSQIHFHWGADMMEGSDHTVDDRRYPGE 525
           ++ N G++  +  + ++ +  L GG   + +   Q HF+W     +GS+HT D ++   E
Sbjct: 38  EIFNVGHSFHVDFEDRSNQSVLTGGYVAETYRLWQFHFYWHQTDEQGSEHTRDGKKCASE 97

Query: 526 MQVTFFRSE 552
           + V  + SE
Sbjct: 98  LHVINWNSE 106


>UniRef50_A5FDD4 Cluster: Putative uncharacterized protein precursor;
            n=1; Flavobacterium johnsoniae UW101|Rep: Putative
            uncharacterized protein precursor - Flavobacterium
            johnsoniae UW101
          Length = 1163

 Score = 39.1 bits (87), Expect = 0.098
 Identities = 19/53 (35%), Positives = 30/53 (56%)
 Frame = +1

Query: 220  IYYWSDFEGHLPTPINVSITGSIPYTCPELKWYNFDVFPHKVKLSNTGYTVLI 378
            I+Y S  EG      N ++T +IP TCP++    + V P+   LS +GY+V +
Sbjct: 867  IHYTSSIEGPHDICENQTVTYTIPGTCPDIPVIQWSVTPNLTILSTSGYSVTV 919


>UniRef50_P22748 Cluster: Carbonic anhydrase 4 precursor; n=15;
           Eutheria|Rep: Carbonic anhydrase 4 precursor - Homo
           sapiens (Human)
          Length = 312

 Score = 39.1 bits (87), Expect = 0.098
 Identities = 21/92 (22%), Positives = 47/92 (51%), Gaps = 2/92 (2%)
 Frame = +1

Query: 349 LSNTGYTVLIGAKWKAERPYLEGGPFQDKHIFSQIHFHWGADMMEGSDHTVDDRRYPGEM 528
           + N G++V++  + KA    + GG     +   Q+H HW     +GS+H++D   +  EM
Sbjct: 83  VQNNGHSVMMLLENKAS---ISGGGLPAPYQAKQLHLHWSDLPYKGSEHSLDGEHFAMEM 139

Query: 529 QVTFFRSEYMTQ--EEALRHPDGVVMICYLIK 618
            +   + +  ++  +EA    D + ++ +L++
Sbjct: 140 HIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVE 171


>UniRef50_O93587 Cluster: Carbonic anhydrase; n=5; Percomorpha|Rep:
           Carbonic anhydrase - Platichthys flesus (European
           flounder)
          Length = 259

 Score = 38.3 bits (85), Expect = 0.17
 Identities = 18/56 (32%), Positives = 27/56 (48%)
 Frame = +1

Query: 334 PHKVKLSNTGYTVLIGAKWKAERPYLEGGPFQDKHIFSQIHFHWGADMMEGSDHTV 501
           P    + N G++  +      +   L+ GP    +   Q HFHWGA   +GS+HTV
Sbjct: 52  PTARSILNNGHSFQVTFIDDTDSSTLKDGPISGVYRLKQFHFHWGACDEKGSEHTV 107


>UniRef50_A6QR76 Cluster: Carbonic anhydrase 2; n=1; Amphimedon
           queenslandica|Rep: Carbonic anhydrase 2 - Amphimedon
           queenslandica
          Length = 279

 Score = 36.3 bits (80), Expect = 0.69
 Identities = 19/61 (31%), Positives = 26/61 (42%)
 Frame = +1

Query: 436 HIFSQIHFHWGADMMEGSDHTVDDRRYPGEMQVTFFRSEYMTQEEALRHPDGVVMICYLI 615
           +I  Q HFHWG     GS+H VD   Y  E+   F   +          PD   ++  L+
Sbjct: 115 YILRQFHFHWGDQPGCGSEHLVDGSSYDAELH--FVHEKESPTSNVPNAPDQFAVLGVLL 172

Query: 616 K 618
           K
Sbjct: 173 K 173


>UniRef50_UPI0000EB222F Cluster: UPI0000EB222F related cluster; n=1;
           Canis lupus familiaris|Rep: UPI0000EB222F UniRef100
           entry - Canis familiaris
          Length = 160

 Score = 35.5 bits (78), Expect = 1.2
 Identities = 12/40 (30%), Positives = 24/40 (60%)
 Frame = +1

Query: 409 LEGGPFQDKHIFSQIHFHWGADMMEGSDHTVDDRRYPGEM 528
           + GGP    H   +I  H+G++  +GS+H ++ + + GE+
Sbjct: 17  ISGGPMTYSHRLEEIRLHFGSEDSQGSEHLLNGQAFSGEV 56


>UniRef50_A6QR77 Cluster: Carbonic anhydrase 3; n=1; Amphimedon
           queenslandica|Rep: Carbonic anhydrase 3 - Amphimedon
           queenslandica
          Length = 295

 Score = 35.5 bits (78), Expect = 1.2
 Identities = 28/110 (25%), Positives = 52/110 (47%), Gaps = 4/110 (3%)
 Frame = +1

Query: 211 LQWIYYWSDF-EGHLPTPINVSITGSIP---YTCPELKWYNFDVFPHKVKLSNTGYTVLI 378
           + W   +  F  G   +PI++ IT ++     T   L+  N+D   +   L+N G+T+  
Sbjct: 28  IAWNSLFGSFCSGGRQSPIDI-ITRNVQGGNSTLTPLRMTNWDTSVNGYVLNN-GHTLKF 85

Query: 379 GAKWKAERPYLEGGPFQDKHIFSQIHFHWGADMMEGSDHTVDDRRYPGEM 528
                +    ++   F   +   Q HFHWG + M GS++ V++  + GE+
Sbjct: 86  SPSSASSEARVQ--TFISTYKLLQFHFHWGPNNMVGSENKVNNTFFSGEL 133


>UniRef50_UPI0000ECC003 Cluster: UPI0000ECC003 related cluster; n=1;
           Gallus gallus|Rep: UPI0000ECC003 UniRef100 entry -
           Gallus gallus
          Length = 304

 Score = 35.1 bits (77), Expect = 1.6
 Identities = 25/90 (27%), Positives = 43/90 (47%), Gaps = 3/90 (3%)
 Frame = +1

Query: 214 QWIYYWSDFEGHLPTPINVSITGSI--PYTCP-ELKWYNFDVFPHKVKLSNTGYTVLIGA 384
           QW  ++    G + +PIN++   +I  P   P +L  Y+       + L N G+TV++  
Sbjct: 15  QWAKHFPACSGTMQSPININTETTIFSPQLRPIQLSGYSLPA-SQMLALKNNGHTVVLKL 73

Query: 385 KWKAERPYLEGGPFQDKHIFSQIHFHWGAD 474
               E   + GG +  ++   Q+H HWG D
Sbjct: 74  P---ESLAITGG-YAQQYRAVQLHLHWGXD 99


>UniRef50_Q3U3I1 Cluster: NOD-derived CD11c +ve dendritic cells
           cDNA, RIKEN full-length enriched library,
           clone:F630105N05 product:carbonic anhydrase 4, full
           insert sequence; n=3; Murinae|Rep: NOD-derived CD11c +ve
           dendritic cells cDNA, RIKEN full-length enriched
           library, clone:F630105N05 product:carbonic anhydrase 4,
           full insert sequence - Mus musculus (Mouse)
          Length = 315

 Score = 35.1 bits (77), Expect = 1.6
 Identities = 13/40 (32%), Positives = 21/40 (52%)
 Frame = +1

Query: 415 GGPFQDKHIFSQIHFHWGADMMEGSDHTVDDRRYPGEMQV 534
           GG    ++   Q+H HW      GS+H++D R +  EM +
Sbjct: 101 GGDLPARYEAVQLHLHWSNGNDNGSEHSIDGRHFAMEMHI 140


>UniRef50_A0E1X6 Cluster: Chromosome undetermined scaffold_74, whole
           genome shotgun sequence; n=3; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_74,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 642

 Score = 34.3 bits (75), Expect = 2.8
 Identities = 20/54 (37%), Positives = 28/54 (51%), Gaps = 4/54 (7%)
 Frame = -3

Query: 637 RIHSVQPLSNNISLQLRRGD----AELPPASCTQIGRTLPAFHQDTFYRRLCGH 488
           +I   +PL NN SL+ R+ D     E+ P +C QI   +P   Q + YR   GH
Sbjct: 321 KIQDFKPLINNHSLKKRKDDHILTTEVLPQNCLQIKECIPTPDQRSQYRISLGH 374


>UniRef50_Q6FQK5 Cluster: Candida glabrata strain CBS138 chromosome
           I complete sequence; n=1; Candida glabrata|Rep: Candida
           glabrata strain CBS138 chromosome I complete sequence -
           Candida glabrata (Yeast) (Torulopsis glabrata)
          Length = 724

 Score = 33.9 bits (74), Expect = 3.7
 Identities = 21/67 (31%), Positives = 37/67 (55%), Gaps = 1/67 (1%)
 Frame = -1

Query: 678 ILENPSTTQLKCLSGFTPYNLYQITYHYNSVG-VTQSFLLRHVLRSEERYLHFTRIPSIV 502
           I+ N + +Q K + G + Y+L   T +YN +    ++++     +   RY H ++IP+IV
Sbjct: 44  IIPNAAASQRKSIIGQSDYDLANGTTNYNDLANEARNYVAIPQEQLLHRYEHDSQIPTIV 103

Query: 501 DCVVTAL 481
           D  VT L
Sbjct: 104 DTNVTKL 110


>UniRef50_Q1DMJ1 Cluster: Predicted protein; n=1; Coccidioides
           immitis|Rep: Predicted protein - Coccidioides immitis
          Length = 348

 Score = 33.1 bits (72), Expect = 6.4
 Identities = 16/52 (30%), Positives = 26/52 (50%), Gaps = 1/52 (1%)
 Frame = +1

Query: 388 WKAERPYLEGGPFQDKHIFSQIHFHWGADMMEGSDHTVDDRR-YPGEMQVTF 540
           +K  +P  E G FQD + F  +H +W  D  +     + DR+ Y  ++Q  F
Sbjct: 294 YKHIQPIFEKGHFQDSNFFLMMHKYWSRDASDLPVQKITDRKAYLDKLQEAF 345


>UniRef50_Q5BY01 Cluster: SJCHGC07514 protein; n=1; Schistosoma
           japonicum|Rep: SJCHGC07514 protein - Schistosoma
           japonicum (Blood fluke)
          Length = 204

 Score = 32.7 bits (71), Expect = 8.5
 Identities = 29/123 (23%), Positives = 51/123 (41%), Gaps = 3/123 (2%)
 Frame = +1

Query: 229 WSD-FEGHLPTPINVSITGSI-PYTCPELKWYNFDVFPHKVKLSNTGYTVLIGAKWKAER 402
           WS  ++G + +PIN+S    +       L+    D     V++ NTG  + I       +
Sbjct: 83  WSACYQGKMQSPINISTKHLVFDSNLRPLRILGSDK-EIDVEMVNTGQDLQIKILDSTTQ 141

Query: 403 PYLEGGPFQDKHIFSQIHFHWGADMMEGSDHTVDDRRYPGEMQVTFFRSE-YMTQEEALR 579
                GP    +    +   +G++   GSDH ++   +P E+Q+  F    Y     AL 
Sbjct: 142 IVFSEGPLTYDYELFGVLIKFGSESNRGSDHQINGITFPAELQLYAFNFVLYQNFSTALS 201

Query: 580 HPD 588
            P+
Sbjct: 202 KPN 204


>UniRef50_Q7S1M6 Cluster: Putative uncharacterized protein
           NCU09281.1; n=2; Sordariales|Rep: Putative
           uncharacterized protein NCU09281.1 - Neurospora crassa
          Length = 880

 Score = 32.7 bits (71), Expect = 8.5
 Identities = 15/57 (26%), Positives = 27/57 (47%)
 Frame = +1

Query: 250 LPTPINVSITGSIPYTCPELKWYNFDVFPHKVKLSNTGYTVLIGAKWKAERPYLEGG 420
           L +P+      S+ +  P+ KWY+F    H++  ++ G   + G  W     Y+ GG
Sbjct: 707 LVSPVVEDDAHSVTFYLPQGKWYDFFTH-HRIDQTSAGTVTVSGVGWDQIPVYIRGG 762


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 715,751,570
Number of Sequences: 1657284
Number of extensions: 15287673
Number of successful extensions: 39833
Number of sequences better than 10.0: 141
Number of HSP's better than 10.0 without gapping: 38205
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 39778
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 52892566912
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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