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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= bmte10c23
         (364 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_Q03393 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase...   117   6e-26
UniRef50_P48611 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase...   114   5e-25
UniRef50_UPI0000585023 Cluster: PREDICTED: hypothetical protein;...   109   2e-23
UniRef50_Q1ZXI0 Cluster: 6-pyruvoyltetrahydropterin synthase; n=...    99   1e-20
UniRef50_Q60PJ1 Cluster: Putative uncharacterized protein CBG222...    85   3e-16
UniRef50_Q2PY17 Cluster: 6-pyruvoyl-tetrahydropterin synthase; n...    78   4e-14
UniRef50_Q26EI1 Cluster: 6-pyruvoyl-tetrahydropterin synthase; n...    72   3e-12
UniRef50_P80081 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase...    72   3e-12
UniRef50_A3XR13 Cluster: 6-pyruvoyltetrahydropterin synthase; n=...    69   3e-11
UniRef50_Q9WXP5 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase...    66   1e-10
UniRef50_Q1IPI9 Cluster: 6-pyruvoyl tetrahydropterin synthase; n...    66   2e-10
UniRef50_Q675S7 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase...    64   7e-10
UniRef50_Q0I727 Cluster: 6-pyruvoyl-tetrahydropterin synthase ho...    63   2e-09
UniRef50_Q5KZY1 Cluster: 6-pyruvoyltetrahydropterin synthase; n=...    62   4e-09
UniRef50_Q8KEA7 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase...    59   2e-08
UniRef50_Q6ARY1 Cluster: Related to 6-pyruvoyl tetrahydropterin ...    57   1e-07
UniRef50_Q1IPJ0 Cluster: 6-pyruvoyl tetrahydropterin synthase; n...    56   3e-07
UniRef50_Q31FT9 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase...    54   6e-07
UniRef50_A1ZSU4 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase...    54   1e-06
UniRef50_Q0LLP6 Cluster: Putative uncharacterized protein; n=1; ...    50   1e-05
UniRef50_Q028J7 Cluster: Putative uncharacterized protein; n=1; ...    49   2e-05
UniRef50_Q2IJB0 Cluster: 6-pyruvoyl tetrahydropterin synthase; n...    46   2e-04
UniRef50_Q8R7N5 Cluster: 6-pyruvoyl-tetrahydropterin synthase; n...    46   3e-04
UniRef50_P65872 Cluster: Putative 6-pyruvoyl tetrahydrobiopterin...    44   6e-04
UniRef50_Q89SC1 Cluster: Bll2482 protein; n=6; Bradyrhizobiaceae...    43   0.001
UniRef50_A6EFM8 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase...    43   0.001
UniRef50_Q0BPQ0 Cluster: Queuosine biosynthesis protein queD; n=...    42   0.004
UniRef50_Q2LVK6 Cluster: Queuosine biosynthesis protein; n=5; Pr...    41   0.006
UniRef50_A0PNB2 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase...    41   0.006
UniRef50_Q98AM2 Cluster: Mll8751 protein; n=5; Proteobacteria|Re...    40   0.014
UniRef50_Q1IHK8 Cluster: Putative uncharacterized protein; n=2; ...    40   0.014
UniRef50_Q64Q92 Cluster: 6-pyruvoyl-tetrahydropterin synthase; n...    40   0.018
UniRef50_Q4LA59 Cluster: Similar to 6-pyruvoyl tetrahydropterin ...    38   0.072
UniRef50_Q1GPS3 Cluster: Putative uncharacterized protein; n=4; ...    37   0.13 
UniRef50_A1HNF1 Cluster: Putative uncharacterized protein; n=1; ...    36   0.17 
UniRef50_A0LE55 Cluster: Putative uncharacterized protein; n=3; ...    36   0.17 
UniRef50_Q4A0G7 Cluster: Putative 6-pyruvoyl tetrahydrobiopterin...    36   0.22 
UniRef50_Q6MLN9 Cluster: 6-pyruvoyltetrahydropterin synthase; n=...    36   0.29 
UniRef50_Q8TS49 Cluster: 6-pyruvoyltetrahydropterin synthase; n=...    36   0.29 
UniRef50_A4EHB1 Cluster: 6-pyruvoyl tetrahydropterin synthase; n...    35   0.51 
UniRef50_Q81TC6 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase...    34   0.89 
UniRef50_A6GHT7 Cluster: Putative uncharacterized protein; n=1; ...    34   0.89 
UniRef50_Q9UYV0 Cluster: PtpS-like 6-pyruvoyl-tetrahydropterin s...    34   0.89 
UniRef50_Q469A8 Cluster: 6-pyruvoyltetrahydropterin synthase; n=...    33   1.6  
UniRef50_Q1D8H8 Cluster: Putative uncharacterized protein; n=1; ...    33   2.1  
UniRef50_Q890G9 Cluster: Putative uncharacterized protein lp_005...    32   2.7  
UniRef50_Q3ZW85 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase...    32   2.7  
UniRef50_Q5E2Z0 Cluster: Putative uncharacterized protein; n=1; ...    31   6.3  
UniRef50_Q1NNT9 Cluster: Putative uncharacterized protein; n=3; ...    31   6.3  
UniRef50_A2Q2N7 Cluster: Putative uncharacterized protein; n=1; ...    31   6.3  
UniRef50_A7AMF5 Cluster: Rab7; n=2; Babesia bovis|Rep: Rab7 - Ba...    31   6.3  
UniRef50_A3LY22 Cluster: Predicted protein; n=1; Pichia stipitis...    31   6.3  
UniRef50_A1RYM7 Cluster: Extracellular solute-binding protein, f...    31   6.3  
UniRef50_UPI000023CB0A Cluster: hypothetical protein FG02847.1; ...    31   8.3  
UniRef50_Q54JY9 Cluster: Putative uncharacterized protein; n=1; ...    31   8.3  
UniRef50_Q4YBM6 Cluster: Putative uncharacterized protein; n=6; ...    31   8.3  
UniRef50_Q4Q2S9 Cluster: Putative uncharacterized protein; n=3; ...    31   8.3  

>UniRef50_Q03393 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase;
           n=35; Eumetazoa|Rep: 6-pyruvoyl tetrahydrobiopterin
           synthase - Homo sapiens (Human)
          Length = 145

 Score =  117 bits (282), Expect = 6e-26
 Identities = 51/89 (57%), Positives = 70/89 (78%)
 Frame = +3

Query: 96  LVTVKGPVDPQXGMVMNITDLKKYIKTAXLEPLDHKNLDNDVPYFKTMASTTENVAIYVW 275
           +VTV G +DP  GMVMN+ DLKKY++ A ++PLDHKNLD DVPYF  + STTENVA+Y+W
Sbjct: 56  VVTVHGEIDPATGMVMNLADLKKYMEEAIMQPLDHKNLDMDVPYFADVVSTTENVAVYIW 115

Query: 276 DQLQRIMEKPQLLHEVKILETEKNHVVYR 362
           D LQ+++    +L++VK+ ET+ N VVY+
Sbjct: 116 DNLQKVL-PVGVLYKVKVYETDNNIVVYK 143


>UniRef50_P48611 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase;
           n=5; Endopterygota|Rep: 6-pyruvoyl tetrahydrobiopterin
           synthase - Drosophila melanogaster (Fruit fly)
          Length = 168

 Score =  114 bits (274), Expect = 5e-25
 Identities = 49/88 (55%), Positives = 69/88 (78%)
 Frame = +3

Query: 99  VTVKGPVDPQXGMVMNITDLKKYIKTAXLEPLDHKNLDNDVPYFKTMASTTENVAIYVWD 278
           +TV+GP+D + GMV+NIT+LK+ I+T  ++ LDHKNLD DV YF    STTEN+A+Y+WD
Sbjct: 52  ITVRGPIDRRTGMVLNITELKEAIETVIMKRLDHKNLDKDVEYFANTPSTTENLAVYIWD 111

Query: 279 QLQRIMEKPQLLHEVKILETEKNHVVYR 362
            ++  ++KP+LL+EVKI ET KN + YR
Sbjct: 112 NIRLQLKKPELLYEVKIHETPKNIISYR 139


>UniRef50_UPI0000585023 Cluster: PREDICTED: hypothetical protein;
           n=2; Strongylocentrotus purpuratus|Rep: PREDICTED:
           hypothetical protein - Strongylocentrotus purpuratus
          Length = 149

 Score =  109 bits (261), Expect = 2e-23
 Identities = 48/88 (54%), Positives = 65/88 (73%)
 Frame = +3

Query: 99  VTVKGPVDPQXGMVMNITDLKKYIKTAXLEPLDHKNLDNDVPYFKTMASTTENVAIYVWD 278
           +T++G V P  GMVMNI+DLK Y+K   L+ LDHKNLD DV YF++  ST EN+AI++WD
Sbjct: 60  LTLRGKVYPVTGMVMNISDLKTYMKNGFLDLLDHKNLDKDVNYFRSNVSTVENIAIFIWD 119

Query: 279 QLQRIMEKPQLLHEVKILETEKNHVVYR 362
           ++ + +  P LL EVK+ ET+KN  VYR
Sbjct: 120 RMAKCLPDPSLLFEVKVHETDKNIAVYR 147


>UniRef50_Q1ZXI0 Cluster: 6-pyruvoyltetrahydropterin synthase; n=1;
           Dictyostelium discoideum AX4|Rep:
           6-pyruvoyltetrahydropterin synthase - Dictyostelium
           discoideum AX4
          Length = 135

 Score =   99 bits (238), Expect = 1e-20
 Identities = 47/88 (53%), Positives = 64/88 (72%)
 Frame = +3

Query: 99  VTVKGPVDPQXGMVMNITDLKKYIKTAXLEPLDHKNLDNDVPYFKTMASTTENVAIYVWD 278
           V++KG V    GM MNIT+LK+ +K   ++ LDHKNL+NDVP  K + +TTEN++I++WD
Sbjct: 48  VSIKGAVKEDIGMFMNITELKEILKEKVMDKLDHKNLENDVPELKGIVTTTENLSIFIWD 107

Query: 279 QLQRIMEKPQLLHEVKILETEKNHVVYR 362
           QL   ++    L+EVKILETE N VVYR
Sbjct: 108 QLFPSLK--DFLYEVKILETENNFVVYR 133


>UniRef50_Q60PJ1 Cluster: Putative uncharacterized protein CBG22232;
           n=1; Caenorhabditis briggsae|Rep: Putative
           uncharacterized protein CBG22232 - Caenorhabditis
           briggsae
          Length = 137

 Score = 85.4 bits (202), Expect = 3e-16
 Identities = 40/88 (45%), Positives = 59/88 (67%)
 Frame = +3

Query: 99  VTVKGPVDPQXGMVMNITDLKKYIKTAXLEPLDHKNLDNDVPYFKTMASTTENVAIYVWD 278
           V ++G VDP  GMV ++  LKK +    L+ +DH+NLD DV +FKT  ST+ENVAIY++ 
Sbjct: 49  VKLRGEVDPVSGMVYDLAKLKKEMNLV-LDTVDHRNLDKDVEFFKTTVSTSENVAIYMYQ 107

Query: 279 QLQRIMEKPQLLHEVKILETEKNHVVYR 362
           +L+ +M  P +L++  I ET KN   Y+
Sbjct: 108 KLKSVMSNPSVLYKCTIEETPKNVFTYK 135


>UniRef50_Q2PY17 Cluster: 6-pyruvoyl-tetrahydropterin synthase; n=2;
           Bacteria|Rep: 6-pyruvoyl-tetrahydropterin synthase -
           uncultured marine bacterium Ant39E11
          Length = 137

 Score = 78.2 bits (184), Expect = 4e-14
 Identities = 36/89 (40%), Positives = 59/89 (66%), Gaps = 1/89 (1%)
 Frame = +3

Query: 96  LVTVKGPVDPQXGMVMNITDLKKYIKTAXLEPLDHKNLDNDVPYFKTMASTTENVAIYVW 275
           +VTVKG V+   G VMN+ DLK  + +  ++ +DH+NL++DVP+ + +  +TEN+A+  W
Sbjct: 46  IVTVKGEVNTDTGFVMNMVDLKAIMDSEIIQHVDHRNLNHDVPFMQGIMPSTENLAMIFW 105

Query: 276 DQLQ-RIMEKPQLLHEVKILETEKNHVVY 359
            Q++  I +    LH ++I+ETE N V Y
Sbjct: 106 QQIEGPIAKHGAALHCIRIVETENNMVEY 134


>UniRef50_Q26EI1 Cluster: 6-pyruvoyl-tetrahydropterin synthase; n=5;
           Bacteroidetes|Rep: 6-pyruvoyl-tetrahydropterin synthase
           - Flavobacteria bacterium BBFL7
          Length = 136

 Score = 72.1 bits (169), Expect = 3e-12
 Identities = 34/88 (38%), Positives = 58/88 (65%)
 Frame = +3

Query: 99  VTVKGPVDPQXGMVMNITDLKKYIKTAXLEPLDHKNLDNDVPYFKTMASTTENVAIYVWD 278
           V V G VDP+ G ++++  LK  IK+   +  DHKNL+ +VP FKT+  T EN+A  +++
Sbjct: 48  VGVTGKVDPETGYLIDLKILKDVIKSEVEDAFDHKNLNVEVPEFKTLNPTAENIAYVIYN 107

Query: 279 QLQRIMEKPQLLHEVKILETEKNHVVYR 362
           +++  ++    + E+K+ ETE+N VVY+
Sbjct: 108 KIKAKLDSKYDI-EIKLYETERNFVVYK 134


>UniRef50_P80081 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase;
           n=1; Salmo salar|Rep: 6-pyruvoyl tetrahydrobiopterin
           synthase - Salmo salar (Atlantic salmon)
          Length = 103

 Score = 72.1 bits (169), Expect = 3e-12
 Identities = 39/76 (51%), Positives = 53/76 (69%)
 Frame = +3

Query: 135 MVMNITDLKKYIKTAXLEPLDHKNLDNDVPYFKTMASTTENVAIYVWDQLQRIMEKPQLL 314
           +VMNIT++K++I+     PLDHKNLD DVPYF  +     NVA+Y+ D + + +    LL
Sbjct: 34  LVMNITNIKEHIEEVI--PLDHKNLDKDVPYFANV-----NVAVYIXDNMVKQL-PANLL 85

Query: 315 HEVKILETEKNHVVYR 362
           +EVKI ET+KN VVYR
Sbjct: 86  YEVKIHETDKNIVVYR 101


>UniRef50_A3XR13 Cluster: 6-pyruvoyltetrahydropterin synthase; n=13;
           Bacteroidetes|Rep: 6-pyruvoyltetrahydropterin synthase -
           Leeuwenhoekiella blandensis MED217
          Length = 137

 Score = 68.9 bits (161), Expect = 3e-11
 Identities = 33/88 (37%), Positives = 53/88 (60%)
 Frame = +3

Query: 96  LVTVKGPVDPQXGMVMNITDLKKYIKTAXLEPLDHKNLDNDVPYFKTMASTTENVAIYVW 275
           +V V G +DP+ G V+++  LK  IK+   EP DHKNL+ DV  F  +  T EN+ + ++
Sbjct: 48  IVAVTGEIDPKTGFVIDLKVLKDLIKSEVEEPFDHKNLNLDVAEFSQLNPTAENICVVIY 107

Query: 276 DQLQRIMEKPQLLHEVKILETEKNHVVY 359
           D+L+  ++  +   EV + ET +N V Y
Sbjct: 108 DRLKAKLD-AKFAIEVTLYETPRNSVTY 134


>UniRef50_Q9WXP5 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase,
           putative; n=9; Bacteria|Rep: 6-pyruvoyl
           tetrahydrobiopterin synthase, putative - Thermotoga
           maritima
          Length = 120

 Score = 66.5 bits (155), Expect = 1e-10
 Identities = 39/90 (43%), Positives = 59/90 (65%), Gaps = 1/90 (1%)
 Frame = +3

Query: 96  LVTVKGPVDPQXGMVMNITDLKKYIKTAXLEPLDHKNLDNDVPYFKTMASTTENVAIYVW 275
           +V ++GP++ +  MVM+  +LKK ++   +  LDH  L ND+  F     TTE VAI++W
Sbjct: 33  VVKIEGPLNEEE-MVMDFAELKKIVEELVISKLDHSYL-NDM--FDQ--PTTERVAIWIW 86

Query: 276 DQLQRIMEKPQL-LHEVKILETEKNHVVYR 362
           DQL + MEK  + LHE+++ ETE + VVYR
Sbjct: 87  DQLSKEMEKRGVRLHEIELWETETSGVVYR 116


>UniRef50_Q1IPI9 Cluster: 6-pyruvoyl tetrahydropterin synthase; n=2;
           Acidobacteria|Rep: 6-pyruvoyl tetrahydropterin synthase
           - Acidobacteria bacterium (strain Ellin345)
          Length = 137

 Score = 66.1 bits (154), Expect = 2e-10
 Identities = 32/87 (36%), Positives = 53/87 (60%)
 Frame = +3

Query: 99  VTVKGPVDPQXGMVMNITDLKKYIKTAXLEPLDHKNLDNDVPYFKTMASTTENVAIYVWD 278
           VTVKG VD   G V+++  LK+ +    ++ +DH+ L+++VP FK+   TTEN+AI +W 
Sbjct: 48  VTVKGTVDATTGFVVDLKQLKEIMNREVVDAMDHRYLNHEVPEFKSQIPTTENIAIAIWK 107

Query: 279 QLQRIMEKPQLLHEVKILETEKNHVVY 359
           +L+  +   + LH V++ E     V Y
Sbjct: 108 RLEGKLHVAK-LHRVRLYEMHDLWVDY 133


>UniRef50_Q675S7 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase;
           n=1; Oikopleura dioica|Rep: 6-pyruvoyl
           tetrahydrobiopterin synthase - Oikopleura dioica
           (Tunicate)
          Length = 136

 Score = 64.1 bits (149), Expect = 7e-10
 Identities = 35/84 (41%), Positives = 52/84 (61%), Gaps = 1/84 (1%)
 Frame = +3

Query: 105 VKGPVDPQXGMVMNITDLKKYIKTAXLEPLDHKNLDNDVPYFKTMASTTENVAIYVWDQL 284
           ++G +  + GMVMN+ DLK  +    L  LDH+N+D DV YFK + ST ENVA +++ QL
Sbjct: 50  IEGEIIKETGMVMNLVDLKVAMWKV-LSQLDHRNVDKDVEYFKNVPSTAENVAQWIFIQL 108

Query: 285 -QRIMEKPQLLHEVKILETEKNHV 353
            Q +      L ++ + ET+KN V
Sbjct: 109 SQELPTGSYHLKKIILDETDKNRV 132


>UniRef50_Q0I727 Cluster: 6-pyruvoyl-tetrahydropterin synthase
           homolog; n=35; Cyanobacteria|Rep:
           6-pyruvoyl-tetrahydropterin synthase homolog -
           Synechococcus sp. (strain CC9311)
          Length = 306

 Score = 62.9 bits (146), Expect = 2e-09
 Identities = 29/84 (34%), Positives = 50/84 (59%), Gaps = 1/84 (1%)
 Frame = +3

Query: 99  VTVKGPVDPQXGMVMNITDLKKYIKTAXLEPLDHKNLDNDVPYFKTMASTTENVAIYVWD 278
           VTV+G +DP+ GMV ++  L++ +    +EP DH  L+ DV +F     T EN+A+++ D
Sbjct: 199 VTVRGSIDPRTGMVCDLAALQRLVSDLVVEPFDHTFLNKDVAHFADCVPTAENIALHIVD 258

Query: 279 QLQR-IMEKPQLLHEVKILETEKN 347
           +L   +      LH+V++ E+  N
Sbjct: 259 RLTTPVRAIGAQLHKVRLQESPNN 282


>UniRef50_Q5KZY1 Cluster: 6-pyruvoyltetrahydropterin synthase; n=6;
           Bacteria|Rep: 6-pyruvoyltetrahydropterin synthase -
           Geobacillus kaustophilus
          Length = 134

 Score = 61.7 bits (143), Expect = 4e-09
 Identities = 31/87 (35%), Positives = 49/87 (56%)
 Frame = +3

Query: 99  VTVKGPVDPQXGMVMNITDLKKYIKTAXLEPLDHKNLDNDVPYFKTMASTTENVAIYVWD 278
           VTV G  DP  GMV+N+ +L + +    L   DHK+L+ D   FK +  T EN+ I +W+
Sbjct: 44  VTVIGKPDPITGMVVNLAELDEIVNREVLVKFDHKHLNLDTDEFKQINPTAENIVIVIWE 103

Query: 279 QLQRIMEKPQLLHEVKILETEKNHVVY 359
            L   +     L+++ + ET+KN+  Y
Sbjct: 104 LLAPHLSS---LYKIGLWETQKNYFEY 127


>UniRef50_Q8KEA7 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase,
           putative; n=10; Chlorobiaceae|Rep: 6-pyruvoyl
           tetrahydrobiopterin synthase, putative - Chlorobium
           tepidum
          Length = 149

 Score = 59.3 bits (137), Expect = 2e-08
 Identities = 32/95 (33%), Positives = 55/95 (57%), Gaps = 4/95 (4%)
 Frame = +3

Query: 90  LFLVTVKGPVDPQXGMVMNITDLKKYIKTAXLEPLDHKNLDNDVPYFKTMASTTENVAIY 269
           L  +T+ G +D + G + ++ +LKK ++   +   DH++L+++V        TTE +A+ 
Sbjct: 53  LLEITLSGIIDRKTGYLFDLKELKKILEEEIVARFDHRHLNHEVNELAGHVPTTEILAVI 112

Query: 270 VWD----QLQRIMEKPQLLHEVKILETEKNHVVYR 362
           VW+    +L+ I ++   LHEV I ET KN V YR
Sbjct: 113 VWEILDSRLKTITKQEVSLHEVIIHETGKNSVTYR 147


>UniRef50_Q6ARY1 Cluster: Related to 6-pyruvoyl tetrahydropterin
           synthase; n=1; Desulfotalea psychrophila|Rep: Related to
           6-pyruvoyl tetrahydropterin synthase - Desulfotalea
           psychrophila
          Length = 136

 Score = 56.8 bits (131), Expect = 1e-07
 Identities = 31/90 (34%), Positives = 56/90 (62%), Gaps = 1/90 (1%)
 Frame = +3

Query: 72  TYCIIILFLVTVKGPVDPQXGMVMNITDLKKYIKTAXLEPLDHKNLDNDVPYFKTMASTT 251
           TYC+ I    T+ G V P  GMV+N TDLK+ ++   +   DH +L N++  ++ + +T 
Sbjct: 42  TYCLRI----TITGKVQPN-GMVLNFTDLKQIVEEKIIARYDHSHL-NELEEYRDLPTTA 95

Query: 252 ENVAIYVWDQLQRIMEKPQL-LHEVKILET 338
           EN+++Y++  L   ++K ++ L EV++ ET
Sbjct: 96  ENMSLYIFKVLAACLKKQKVTLTEVQLYET 125


>UniRef50_Q1IPJ0 Cluster: 6-pyruvoyl tetrahydropterin synthase; n=1;
           Acidobacteria bacterium Ellin345|Rep: 6-pyruvoyl
           tetrahydropterin synthase - Acidobacteria bacterium
           (strain Ellin345)
          Length = 135

 Score = 55.6 bits (128), Expect = 3e-07
 Identities = 30/83 (36%), Positives = 51/83 (61%)
 Frame = +3

Query: 99  VTVKGPVDPQXGMVMNITDLKKYIKTAXLEPLDHKNLDNDVPYFKTMASTTENVAIYVWD 278
           VTV G V P  GMV N+ D+ + ++   LE  DH+NL N +  F+ +  TTEN+ + +++
Sbjct: 48  VTVGGQVAPDTGMVYNLADVDRVVRKHILERYDHQNL-NCLKEFQELVPTTENLCLAIFE 106

Query: 279 QLQRIMEKPQLLHEVKILETEKN 347
            L+R + +   L +V++ ET +N
Sbjct: 107 ILKRNLAEIH-LDKVRLEETSQN 128


>UniRef50_Q31FT9 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase;
           n=3; Gammaproteobacteria|Rep: 6-pyruvoyl
           tetrahydrobiopterin synthase - Thiomicrospira crunogena
           (strain XCL-2)
          Length = 125

 Score = 54.4 bits (125), Expect = 6e-07
 Identities = 31/88 (35%), Positives = 49/88 (55%), Gaps = 1/88 (1%)
 Frame = +3

Query: 99  VTVKGPVDPQXGMVMNITDLKKYIKTAXLEPLDHKNLDNDVPYFKTMASTTENVAIYVWD 278
           V V G      GM+++  ++K++ K    E LDH  L ND P+FK    T EN+A Y++ 
Sbjct: 38  VQVVGDKLNDIGMLVDFKEIKRHAKEVISE-LDHTFL-NDHPHFKEKNPTAENIAEYIYK 95

Query: 279 QL-QRIMEKPQLLHEVKILETEKNHVVY 359
           Q+ QRI      +H + + E ++N V+Y
Sbjct: 96  QIQQRIQSSTVKMHSLTVWENDRNCVIY 123


>UniRef50_A1ZSU4 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase;
           n=3; Flexibacteraceae|Rep: 6-pyruvoyl
           tetrahydrobiopterin synthase - Microscilla marina ATCC
           23134
          Length = 158

 Score = 53.6 bits (123), Expect = 1e-06
 Identities = 31/91 (34%), Positives = 51/91 (56%), Gaps = 3/91 (3%)
 Frame = +3

Query: 96  LVTVKGPVDPQXGMVMNITDLKKYIKTAXLEPLDHKNLDNDVPYFKTMASTTENVAIYVW 275
           +VTVKG  D + GMV++   L K ++   +E + +KNL+ DV +      + E + I  W
Sbjct: 46  VVTVKGMPDLETGMVIDYKVLSKIVRREIIEKVHYKNLNLDVDFLAGKMPSCEILIIEFW 105

Query: 276 DQLQRIM--EKPQ-LLHEVKILETEKNHVVY 359
            +L   +  E P+  LH +K++ET+ N V Y
Sbjct: 106 KRLAPAIQQESPRTTLHHLKLVETKNNSVEY 136


>UniRef50_Q0LLP6 Cluster: Putative uncharacterized protein; n=1;
           Herpetosiphon aurantiacus ATCC 23779|Rep: Putative
           uncharacterized protein - Herpetosiphon aurantiacus ATCC
           23779
          Length = 133

 Score = 50.0 bits (114), Expect = 1e-05
 Identities = 32/94 (34%), Positives = 53/94 (56%), Gaps = 6/94 (6%)
 Frame = +3

Query: 90  LFLVTVKGPVDP-----QXGMVMNITDLKKYIKTAXLEPLDHKNLDNDVPYFKTMASTTE 254
           L  V+V+G + P       GMV+++  +K+ +    +  +DH NL ND   F ++ ST E
Sbjct: 33  LLEVSVRGLIQPTRGQSDDGMVIDLEQIKQLVNEIIIARVDHYNL-ND---FLSVPSTAE 88

Query: 255 NVAIYVWDQL-QRIMEKPQLLHEVKILETEKNHV 353
           N+A ++WDQL Q+  E   LL  +++ ET   +V
Sbjct: 89  NIAHWMWDQLEQQAPEFAALLWRIRLWETASGYV 122


>UniRef50_Q028J7 Cluster: Putative uncharacterized protein; n=1;
           Solibacter usitatus Ellin6076|Rep: Putative
           uncharacterized protein - Solibacter usitatus (strain
           Ellin6076)
          Length = 141

 Score = 49.2 bits (112), Expect = 2e-05
 Identities = 26/88 (29%), Positives = 50/88 (56%), Gaps = 5/88 (5%)
 Frame = +3

Query: 99  VTVKGPVDPQXGMVMNITDLKKYIKTAXLEPLDHKNLDNDVPYFKTMASTTENVAIYVWD 278
           V+V+GPVD   G  ++I  L + ++   ++P DH+NL+ +V  F    +T+EN+   +  
Sbjct: 44  VSVRGPVDEATGRTVDIVLLDELVRREVVQPFDHRNLNAEVDAFTKAVATSENLGFEICR 103

Query: 279 QLQRIMEKP-----QLLHEVKILETEKN 347
           +L+R  ++        L +++I ET +N
Sbjct: 104 RLKRNWKEVFPGEWPKLEKIRIGETARN 131


>UniRef50_Q2IJB0 Cluster: 6-pyruvoyl tetrahydropterin synthase; n=2;
           Anaeromyxobacter|Rep: 6-pyruvoyl tetrahydropterin
           synthase - Anaeromyxobacter dehalogenans (strain 2CP-C)
          Length = 129

 Score = 46.4 bits (105), Expect = 2e-04
 Identities = 29/90 (32%), Positives = 48/90 (53%)
 Frame = +3

Query: 93  FLVTVKGPVDPQXGMVMNITDLKKYIKTAXLEPLDHKNLDNDVPYFKTMASTTENVAIYV 272
           F V ++G VDP  GM+ +  D+K+ +    L  +DH+ L NDV        T EN+A ++
Sbjct: 43  FFVALEGEVDPATGMIADFGDVKRIVAEHVLARVDHRTL-NDV----LDNPTAENIARWM 97

Query: 273 WDQLQRIMEKPQLLHEVKILETEKNHVVYR 362
           W+ L+  +     L E+++ E   + V YR
Sbjct: 98  WEVLEPHLAG---LCEIRLYEIPDSCVTYR 124


>UniRef50_Q8R7N5 Cluster: 6-pyruvoyl-tetrahydropterin synthase; n=3;
           Clostridia|Rep: 6-pyruvoyl-tetrahydropterin synthase -
           Thermoanaerobacter tengcongensis
          Length = 122

 Score = 45.6 bits (103), Expect = 3e-04
 Identities = 28/81 (34%), Positives = 49/81 (60%), Gaps = 1/81 (1%)
 Frame = +3

Query: 99  VTVKGPVDPQXGMVMNITDLKKYIKTAXLEPLDHKNLDNDVPYFKTMASTTENVAIYVWD 278
           VTV+G  D + GMV++   LK+ +    ++ LDHK L N+V  F T   T EN+ +++W 
Sbjct: 34  VTVEGYPDEE-GMVLDFVKLKEIVNEKIIKKLDHKYL-NEVLGFNT---TCENILLWMWK 88

Query: 279 QLQRIMEKPQL-LHEVKILET 338
           +L+  ++ P   L+++ + ET
Sbjct: 89  ELEGELKGPNYKLYKLTLWET 109


>UniRef50_P65872 Cluster: Putative 6-pyruvoyl tetrahydrobiopterin
           synthase; n=24; Proteobacteria|Rep: Putative 6-pyruvoyl
           tetrahydrobiopterin synthase - Shigella flexneri
          Length = 121

 Score = 44.4 bits (100), Expect = 6e-04
 Identities = 29/86 (33%), Positives = 46/86 (53%)
 Frame = +3

Query: 105 VKGPVDPQXGMVMNITDLKKYIKTAXLEPLDHKNLDNDVPYFKTMASTTENVAIYVWDQL 284
           + G VDP  G +++  +LK   K    E LDH  L ND+P  +    T+E +A ++WDQ+
Sbjct: 41  ITGEVDPHTGWIIDFAELKAAFKPTY-ERLDHHYL-NDIPGLEN--PTSEVLAKWIWDQV 96

Query: 285 QRIMEKPQLLHEVKILETEKNHVVYR 362
           + ++    LL  V + ET     +YR
Sbjct: 97  KPVV---PLLSAVMVKETCTAGCIYR 119


>UniRef50_Q89SC1 Cluster: Bll2482 protein; n=6;
           Bradyrhizobiaceae|Rep: Bll2482 protein - Bradyrhizobium
           japonicum
          Length = 121

 Score = 43.2 bits (97), Expect = 0.001
 Identities = 26/65 (40%), Positives = 40/65 (61%)
 Frame = +3

Query: 99  VTVKGPVDPQXGMVMNITDLKKYIKTAXLEPLDHKNLDNDVPYFKTMASTTENVAIYVWD 278
           VTV+G  DP+ GMV+++  L++ I+   L  LDHK L+      K    T EN++ +VW+
Sbjct: 37  VTVRGTPDPETGMVVDLGLLQRAIEDVRL-TLDHKFLNKIEALGK---PTLENLSRFVWE 92

Query: 279 QLQRI 293
           +LQ I
Sbjct: 93  RLQHI 97


>UniRef50_A6EFM8 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase,
           putative; n=1; Pedobacter sp. BAL39|Rep: 6-pyruvoyl
           tetrahydrobiopterin synthase, putative - Pedobacter sp.
           BAL39
          Length = 117

 Score = 43.2 bits (97), Expect = 0.001
 Identities = 26/87 (29%), Positives = 50/87 (57%)
 Frame = +3

Query: 99  VTVKGPVDPQXGMVMNITDLKKYIKTAXLEPLDHKNLDNDVPYFKTMASTTENVAIYVWD 278
           V + G  DP  G V +  DLK+ I+   ++ LDH+ L ND+P  +    T+EN+++++W 
Sbjct: 36  VYLSGTPDPHSGWVADFGDLKRGIQ-PFVDLLDHRLL-NDIPGLEN--PTSENLSVWLWQ 91

Query: 279 QLQRIMEKPQLLHEVKILETEKNHVVY 359
           +++ +      L ++++ ET    V+Y
Sbjct: 92  KIKPVF---PALAKIELSETPGTGVIY 115


>UniRef50_Q0BPQ0 Cluster: Queuosine biosynthesis protein queD; n=1;
           Granulibacter bethesdensis CGDNIH1|Rep: Queuosine
           biosynthesis protein queD - Granulobacter bethesdensis
           (strain ATCC BAA-1260 / CGDNIH1)
          Length = 130

 Score = 41.5 bits (93), Expect = 0.004
 Identities = 23/62 (37%), Positives = 39/62 (62%)
 Frame = +3

Query: 99  VTVKGPVDPQXGMVMNITDLKKYIKTAXLEPLDHKNLDNDVPYFKTMASTTENVAIYVWD 278
           V ++G VDP  GM+M++  L++ +  A  + LDH+ LD +VP      +T EN+A+++W 
Sbjct: 47  VVLRGGVDPDSGMLMDLGLLQRKM-NAVRDALDHRLLD-EVP--GLAPATMENIALFIWR 102

Query: 279 QL 284
            L
Sbjct: 103 HL 104


>UniRef50_Q2LVK6 Cluster: Queuosine biosynthesis protein; n=5;
           Proteobacteria|Rep: Queuosine biosynthesis protein -
           Syntrophus aciditrophicus (strain SB)
          Length = 159

 Score = 41.1 bits (92), Expect = 0.006
 Identities = 25/89 (28%), Positives = 53/89 (59%), Gaps = 1/89 (1%)
 Frame = +3

Query: 99  VTVKGPVDPQXGMVMNITDLKKYIKTAXLEPLDHKNLDNDVPYFKTMASTTENVAIYVWD 278
           VTV+     + G+ ++  ++K+ ++ A L  LDH NL N++P F  +  ++EN+A ++++
Sbjct: 71  VTVECEELNEIGIGIDFREVKQSVREA-LHRLDHVNL-NELPQFCDINPSSENIARHLYN 128

Query: 279 QLQRIMEKPQL-LHEVKILETEKNHVVYR 362
           +L R +   ++ +  V++ ET  +   YR
Sbjct: 129 ELSRKLNTEKIRVSRVRVSETPTSKASYR 157


>UniRef50_A0PNB2 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase;
           n=2; Actinomycetales|Rep: 6-pyruvoyl tetrahydrobiopterin
           synthase - Mycobacterium ulcerans (strain Agy99)
          Length = 160

 Score = 41.1 bits (92), Expect = 0.006
 Identities = 24/86 (27%), Positives = 48/86 (55%)
 Frame = +3

Query: 105 VKGPVDPQXGMVMNITDLKKYIKTAXLEPLDHKNLDNDVPYFKTMASTTENVAIYVWDQL 284
           V+GPVDP+ G +++   +K   K   +  LDH  L N++   +    T+E +++++W +L
Sbjct: 42  VEGPVDPRAGWIVDFGKIKDACKPV-IARLDHYYL-NEIDGLEN--PTSEQLSMWIWREL 97

Query: 285 QRIMEKPQLLHEVKILETEKNHVVYR 362
             ++  P ++  V + ET  +  +YR
Sbjct: 98  ATLL--PMMMSAVSVSETCSSGCMYR 121


>UniRef50_Q98AM2 Cluster: Mll8751 protein; n=5; Proteobacteria|Rep:
           Mll8751 protein - Rhizobium loti (Mesorhizobium loti)
          Length = 117

 Score = 39.9 bits (89), Expect = 0.014
 Identities = 20/64 (31%), Positives = 39/64 (60%)
 Frame = +3

Query: 105 VKGPVDPQXGMVMNITDLKKYIKTAXLEPLDHKNLDNDVPYFKTMASTTENVAIYVWDQL 284
           ++GPVDP  G V++  D++  +    L+ LDH+ L N++        T EN+A+++W+Q 
Sbjct: 38  LEGPVDPDTGFVIDFFDVEA-VFGPLLQRLDHQYL-NEIEGLDN--PTAENIAVWIWNQT 93

Query: 285 QRIM 296
           + ++
Sbjct: 94  KPLL 97


>UniRef50_Q1IHK8 Cluster: Putative uncharacterized protein; n=2;
           Acidobacteria|Rep: Putative uncharacterized protein -
           Acidobacteria bacterium (strain Ellin345)
          Length = 125

 Score = 39.9 bits (89), Expect = 0.014
 Identities = 20/66 (30%), Positives = 39/66 (59%)
 Frame = +3

Query: 99  VTVKGPVDPQXGMVMNITDLKKYIKTAXLEPLDHKNLDNDVPYFKTMASTTENVAIYVWD 278
           VT++G      G++++  DLK  +K   ++ LDH+ + ND+P F  +  + EN+A Y +D
Sbjct: 35  VTLQGRELDHAGLLLDFKDLKVVMKPV-VDYLDHQMM-NDIPPFNEVNPSAENIARYFYD 92

Query: 279 QLQRIM 296
           +  + +
Sbjct: 93  ECNKFL 98


>UniRef50_Q64Q92 Cluster: 6-pyruvoyl-tetrahydropterin synthase; n=5;
           Bacteroidales|Rep: 6-pyruvoyl-tetrahydropterin synthase
           - Bacteroides fragilis
          Length = 110

 Score = 39.5 bits (88), Expect = 0.018
 Identities = 27/76 (35%), Positives = 45/76 (59%)
 Frame = +3

Query: 132 GMVMNITDLKKYIKTAXLEPLDHKNLDNDVPYFKTMASTTENVAIYVWDQLQRIMEKPQL 311
           GMV++ T +K+ +K    E LDH+NL+  +P+      T EN+A +V  Q+      PQ 
Sbjct: 47  GMVVDFTQIKQAVK----EKLDHRNLNEVLPF----NPTAENIARWVCKQI------PQ- 91

Query: 312 LHEVKILETEKNHVVY 359
            ++V++ E+E N V+Y
Sbjct: 92  CYKVEVQESEANTVIY 107


>UniRef50_Q4LA59 Cluster: Similar to 6-pyruvoyl tetrahydropterin
           synthase; n=1; Staphylococcus haemolyticus JCSC1435|Rep:
           Similar to 6-pyruvoyl tetrahydropterin synthase -
           Staphylococcus haemolyticus (strain JCSC1435)
          Length = 143

 Score = 37.5 bits (83), Expect = 0.072
 Identities = 23/87 (26%), Positives = 48/87 (55%), Gaps = 2/87 (2%)
 Frame = +3

Query: 99  VTVKGPV-DPQXGMVMNITDLKKYIKTAXLEP-LDHKNLDNDVPYFKTMASTTENVAIYV 272
           V V  P+ D   G+  N  D    I    +EP L+H+ ++  +P    M +T EN+A+++
Sbjct: 54  VDVLSPIGDYGLGLDFNEVDA---IYNKVIEPKLNHQLINETLP---DMNTTAENIAMWI 107

Query: 273 WDQLQRIMEKPQLLHEVKILETEKNHV 353
           WD+ ++ +     ++ +++ ET+++ V
Sbjct: 108 WDEFEQHLPGEHCMYALQLFETDRHGV 134


>UniRef50_Q1GPS3 Cluster: Putative uncharacterized protein; n=4;
           Proteobacteria|Rep: Putative uncharacterized protein -
           Sphingopyxis alaskensis (Sphingomonas alaskensis)
          Length = 124

 Score = 36.7 bits (81), Expect = 0.13
 Identities = 22/64 (34%), Positives = 41/64 (64%), Gaps = 2/64 (3%)
 Frame = +3

Query: 99  VTVKGPVDPQXGMVMNITDLKKYIKTAXLEPLDHKNLD--NDVPYFKTMASTTENVAIYV 272
           VTV+G  DP  GM++++  L++ ++ A  + LDH+ LD  ND+       +T EN++ ++
Sbjct: 37  VTVRGRPDPATGMIVDLGLLERSMEDAR-DALDHRFLDEINDLG-----PATMENLSRWI 90

Query: 273 WDQL 284
           W++L
Sbjct: 91  WNRL 94


>UniRef50_A1HNF1 Cluster: Putative uncharacterized protein; n=1;
           Thermosinus carboxydivorans Nor1|Rep: Putative
           uncharacterized protein - Thermosinus carboxydivorans
           Nor1
          Length = 130

 Score = 36.3 bits (80), Expect = 0.17
 Identities = 23/78 (29%), Positives = 43/78 (55%), Gaps = 1/78 (1%)
 Frame = +3

Query: 123 PQXGMVMNITDLKKYIKTAXLEPLDHKNLDNDVPYFKTMASTTENVAIYVWDQLQRIMEK 302
           P+ GMV++   L   IK   ++ LDHK L++  P+      T+EN+A +++ +L  I+  
Sbjct: 53  PEDGMVIDFGRLSALIKDRVVDKLDHKVLNDCFPF----RPTSENMARHIFIELSAILAN 108

Query: 303 PQL-LHEVKILETEKNHV 353
             + +  V + ET  ++V
Sbjct: 109 EDVNVVRVVLWETPTSYV 126


>UniRef50_A0LE55 Cluster: Putative uncharacterized protein; n=3;
           Deltaproteobacteria|Rep: Putative uncharacterized
           protein - Syntrophobacter fumaroxidans (strain DSM 10017
           / MPOB)
          Length = 127

 Score = 36.3 bits (80), Expect = 0.17
 Identities = 20/82 (24%), Positives = 48/82 (58%), Gaps = 1/82 (1%)
 Frame = +3

Query: 99  VTVKGPVDPQXGMVMNITDLKKYIKTAXLEPLDHKNLDNDVPYFKTMASTTENVAIYVWD 278
           + ++G    + G++++  ++K+  + A L  +DH  L N++P+F     ++EN+A Y+++
Sbjct: 39  IVLRGTELNEIGVLVDFGEVKQATR-ALLSEVDHHYL-NEIPFFADRNPSSENIARYLFE 96

Query: 279 QLQRIMEKPQL-LHEVKILETE 341
           +L    +  +L L+ V   E++
Sbjct: 97  RLAEKFDNDKLRLYRVSAWESD 118


>UniRef50_Q4A0G7 Cluster: Putative 6-pyruvoyl tetrahydrobiopterin
           synthase; n=1; Staphylococcus saprophyticus subsp.
           saprophyticus ATCC 15305|Rep: Putative 6-pyruvoyl
           tetrahydrobiopterin synthase - Staphylococcus
           saprophyticus subsp. saprophyticus (strain ATCC 15305
           /DSM 20229)
          Length = 142

 Score = 35.9 bits (79), Expect = 0.22
 Identities = 19/88 (21%), Positives = 43/88 (48%)
 Frame = +3

Query: 93  FLVTVKGPVDPQXGMVMNITDLKKYIKTAXLEPLDHKNLDNDVPYFKTMASTTENVAIYV 272
           F + +   +D   G+ M+  ++ K  +      +D + ++  +P   T   T EN+AI++
Sbjct: 51  FNIEILSSIDAY-GLAMDFNEVDKLYEREIAPYIDGQLVNETLPEMNT---TAENIAIWI 106

Query: 273 WDQLQRIMEKPQLLHEVKILETEKNHVV 356
           W Q  + + +   L +++  ET+   +V
Sbjct: 107 WHQFNKHLPENNSLQKLEFFETDTQGLV 134


>UniRef50_Q6MLN9 Cluster: 6-pyruvoyltetrahydropterin synthase; n=1;
           Bdellovibrio bacteriovorus|Rep:
           6-pyruvoyltetrahydropterin synthase - Bdellovibrio
           bacteriovorus
          Length = 129

 Score = 35.5 bits (78), Expect = 0.29
 Identities = 14/40 (35%), Positives = 27/40 (67%)
 Frame = +3

Query: 192 LDHKNLDNDVPYFKTMASTTENVAIYVWDQLQRIMEKPQL 311
           LDH++L+  +P FKT   TTEN+ +Y  ++L+  ++  ++
Sbjct: 73  LDHEHLNFVIPEFKTNIPTTENICLYFLEKLKSQVKSEEI 112


>UniRef50_Q8TS49 Cluster: 6-pyruvoyltetrahydropterin synthase; n=3;
           cellular organisms|Rep: 6-pyruvoyltetrahydropterin
           synthase - Methanosarcina acetivorans
          Length = 123

 Score = 35.5 bits (78), Expect = 0.29
 Identities = 24/89 (26%), Positives = 48/89 (53%), Gaps = 2/89 (2%)
 Frame = +3

Query: 99  VTVKGPVDPQXGMVMNITDLKKYIKTAXLEPLDHKNLDNDVPYFK-TMASTTENVAIYVW 275
           V V G      G++M+  +LK+ + +   + LDH N  N++ YF      ++EN+A+Y+ 
Sbjct: 35  VCVAGEKLNDAGIMMDFGELKQNV-SEITKTLDH-NFLNELDYFDDNNPPSSENIAVYIA 92

Query: 276 DQLQRIMEKPQL-LHEVKILETEKNHVVY 359
           + L+ +++ P++ +  V   E+E     Y
Sbjct: 93  NSLKAMLKDPEIRVASVTAWESENACATY 121


>UniRef50_A4EHB1 Cluster: 6-pyruvoyl tetrahydropterin synthase; n=6;
           Bacteria|Rep: 6-pyruvoyl tetrahydropterin synthase -
           Roseobacter sp. CCS2
          Length = 131

 Score = 34.7 bits (76), Expect = 0.51
 Identities = 16/35 (45%), Positives = 24/35 (68%)
 Frame = +3

Query: 183 LEPLDHKNLDNDVPYFKTMASTTENVAIYVWDQLQ 287
           L+PL + NLD +VP FK   +TTE +  ++W QL+
Sbjct: 63  LKPLKYANLD-EVPAFKGKITTTEFLCHHIWQQLR 96


>UniRef50_Q81TC6 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase,
           putative; n=18; Bacilli|Rep: 6-pyruvoyl
           tetrahydrobiopterin synthase, putative - Bacillus
           anthracis
          Length = 163

 Score = 33.9 bits (74), Expect = 0.89
 Identities = 16/67 (23%), Positives = 36/67 (53%)
 Frame = +3

Query: 126 QXGMVMNITDLKKYIKTAXLEPLDHKNLDNDVPYFKTMASTTENVAIYVWDQLQRIMEKP 305
           + G+ ++  D+K+  K      LDH+ L+  +P    M +T EN+ +++++++   + K 
Sbjct: 73  EIGLAIDFGDIKEIWKNEIEIYLDHRYLNETLP---AMNTTAENMVVWIYEKMAEALTKD 129

Query: 306 QLLHEVK 326
              +E K
Sbjct: 130 NRANEYK 136


>UniRef50_A6GHT7 Cluster: Putative uncharacterized protein; n=1;
           Plesiocystis pacifica SIR-1|Rep: Putative
           uncharacterized protein - Plesiocystis pacifica SIR-1
          Length = 129

 Score = 33.9 bits (74), Expect = 0.89
 Identities = 20/61 (32%), Positives = 36/61 (59%), Gaps = 5/61 (8%)
 Frame = +3

Query: 192 LDHKNLDNDVPYFKTMASTTENVAIYVWDQLQRIM-----EKPQLLHEVKILETEKNHVV 356
           +DH+ L N++P F  +  T E++A Y+++ L R +     E+ QL   + + ETE++ V 
Sbjct: 68  IDHRFL-NEIPPFTEVNPTAEHIAAYIYEGLARRLAELAGERVQLA-AITVWETERDSVT 125

Query: 357 Y 359
           Y
Sbjct: 126 Y 126


>UniRef50_Q9UYV0 Cluster: PtpS-like 6-pyruvoyl-tetrahydropterin
           synthase; n=4; Thermococcaceae|Rep: PtpS-like
           6-pyruvoyl-tetrahydropterin synthase - Pyrococcus abyssi
          Length = 115

 Score = 33.9 bits (74), Expect = 0.89
 Identities = 25/85 (29%), Positives = 46/85 (54%)
 Frame = +3

Query: 99  VTVKGPVDPQXGMVMNITDLKKYIKTAXLEPLDHKNLDNDVPYFKTMASTTENVAIYVWD 278
           V V+G +  + G +M+ T+L+K +     E L+H+NL+     F     TTENVA+++ +
Sbjct: 35  VAVEGEI--KRGYIMDFTELRKIVDDIVKE-LNHRNLNK---IFDN--PTTENVALWIAE 86

Query: 279 QLQRIMEKPQLLHEVKILETEKNHV 353
           +++  +     L  V + E + N V
Sbjct: 87  KVEEKLPHKVKLKRVVLWEGKDNGV 111


>UniRef50_Q469A8 Cluster: 6-pyruvoyltetrahydropterin synthase; n=1;
           Methanosarcina barkeri str. Fusaro|Rep:
           6-pyruvoyltetrahydropterin synthase - Methanosarcina
           barkeri (strain Fusaro / DSM 804)
          Length = 112

 Score = 33.1 bits (72), Expect = 1.6
 Identities = 20/72 (27%), Positives = 42/72 (58%), Gaps = 1/72 (1%)
 Frame = +3

Query: 99  VTVKGPVDPQXGMVMNITDLKKYIKTAXLEPLDHKNLDNDVPYFK-TMASTTENVAIYVW 275
           V V G    + G++++  +LK+ + +  +  LDH N  N++ YF  +   ++EN+A Y+ 
Sbjct: 35  VCVAGEKLNEAGVLVDFGELKQKV-SEIVTRLDH-NFLNELEYFNDSNPPSSENIAQYIA 92

Query: 276 DQLQRIMEKPQL 311
             LQ +++ P++
Sbjct: 93  TSLQTMLKDPEI 104


>UniRef50_Q1D8H8 Cluster: Putative uncharacterized protein; n=1;
           Myxococcus xanthus DK 1622|Rep: Putative uncharacterized
           protein - Myxococcus xanthus (strain DK 1622)
          Length = 209

 Score = 32.7 bits (71), Expect = 2.1
 Identities = 24/80 (30%), Positives = 38/80 (47%)
 Frame = +3

Query: 99  VTVKGPVDPQXGMVMNITDLKKYIKTAXLEPLDHKNLDNDVPYFKTMASTTENVAIYVWD 278
           V VK        ++++  DL+  I     E L   N+ N+ PYFKT+  T E V  YV+ 
Sbjct: 118 VWVKARALNHWDVIIDFKDLQDIIVRVCRE-LHDTNI-NEHPYFKTVNCTAERVTEYVFK 175

Query: 279 QLQRIMEKPQLLHEVKILET 338
           Q++  + +   L  V +  T
Sbjct: 176 QVESGLPEGVTLDRVHLRRT 195


>UniRef50_Q890G9 Cluster: Putative uncharacterized protein lp_0052;
           n=1; Lactobacillus plantarum|Rep: Putative
           uncharacterized protein lp_0052 - Lactobacillus
           plantarum
          Length = 122

 Score = 32.3 bits (70), Expect = 2.7
 Identities = 18/48 (37%), Positives = 30/48 (62%)
 Frame = +3

Query: 153 DLKKYIKTAXLEPLDHKNLDNDVPYFKTMASTTENVAIYVWDQLQRIM 296
           D++K +  A L+ L  K L ND+P FKT+  T ENV  Y++ ++ + +
Sbjct: 51  DIEKNLHQA-LDELSGKFL-NDLPEFKTVNPTVENVTEYLFTKIDKTL 96


>UniRef50_Q3ZW85 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase;
           n=3; Dehalococcoides|Rep: 6-pyruvoyl tetrahydrobiopterin
           synthase - Dehalococcoides sp. (strain CBDB1)
          Length = 123

 Score = 32.3 bits (70), Expect = 2.7
 Identities = 24/85 (28%), Positives = 47/85 (55%), Gaps = 1/85 (1%)
 Frame = +3

Query: 111 GPVDPQXGMVMNITDLKKYIKTAXLEPLDHKNLDNDVPYFKTMASTTENVAIYVWDQLQR 290
           G +D + GM  + + LK  +    L+  DH  L ND+  F  +  + EN+A  ++D+L+ 
Sbjct: 40  GELD-ECGMGADFSLLKTRLNEV-LQSYDHTCL-NDLTPFDNINPSAENIAKDIYDKLKT 96

Query: 291 IMEKPQL-LHEVKILETEKNHVVYR 362
           ++ K  + L  V++ E+  + V+Y+
Sbjct: 97  VINKKGVELWGVEVWESPDSSVLYQ 121


>UniRef50_Q5E2Z0 Cluster: Putative uncharacterized protein; n=1;
           Vibrio fischeri ES114|Rep: Putative uncharacterized
           protein - Vibrio fischeri (strain ATCC 700601 / ES114)
          Length = 59

 Score = 31.1 bits (67), Expect = 6.3
 Identities = 15/41 (36%), Positives = 26/41 (63%)
 Frame = +3

Query: 213 NDVPYFKTMASTTENVAIYVWDQLQRIMEKPQLLHEVKILE 335
           ND+   KT  +T +  A  +W +++ I ++ QLLHE+K L+
Sbjct: 7   NDILATKT-TTTKKKQAKRLWREIEEIQDRRQLLHELKELD 46


>UniRef50_Q1NNT9 Cluster: Putative uncharacterized protein; n=3;
           Bacteria|Rep: Putative uncharacterized protein - delta
           proteobacterium MLMS-1
          Length = 154

 Score = 31.1 bits (67), Expect = 6.3
 Identities = 19/72 (26%), Positives = 37/72 (51%)
 Frame = +3

Query: 99  VTVKGPVDPQXGMVMNITDLKKYIKTAXLEPLDHKNLDNDVPYFKTMASTTENVAIYVWD 278
           V + GP   + G +++I +L   +     E  + + L ND+P F  +  + EN+A  +W 
Sbjct: 62  VALDGPELNEHGFLVDIVELAGNLDLVQ-EAYEDRIL-NDLPEFAGLNPSIENLARLIWQ 119

Query: 279 QLQRIMEKPQLL 314
           +L ++    +LL
Sbjct: 120 RLSQLPASDKLL 131


>UniRef50_A2Q2N7 Cluster: Putative uncharacterized protein; n=1;
           Medicago truncatula|Rep: Putative uncharacterized
           protein - Medicago truncatula (Barrel medic)
          Length = 169

 Score = 31.1 bits (67), Expect = 6.3
 Identities = 18/71 (25%), Positives = 37/71 (52%), Gaps = 2/71 (2%)
 Frame = +3

Query: 141 MNITDLKKYIKTAXLEPLDHKNLDNDVPYFKTMASTTENVAIYVWDQLQRIMEK--PQLL 314
           M++ D+ K++KT   E   H+  D ++     + S +EN + +V + L   ++K  PQ +
Sbjct: 12  MDVFDMIKHLKTLYQEQARHERFDWELAIDLILQSLSENFSHFVMNLLMNEIDKFLPQHV 71

Query: 315 HEVKILETEKN 347
             ++ +E   N
Sbjct: 72  SMLRTVERNMN 82


>UniRef50_A7AMF5 Cluster: Rab7; n=2; Babesia bovis|Rep: Rab7 -
           Babesia bovis
          Length = 233

 Score = 31.1 bits (67), Expect = 6.3
 Identities = 22/85 (25%), Positives = 42/85 (49%), Gaps = 3/85 (3%)
 Frame = +3

Query: 93  FLVTVKGPVDPQX---GMVMNITDLKKYIKTAXLEPLDHKNLDNDVPYFKTMASTTENVA 263
           FL+ V+ P DP+     ++ N  D     K +  +  +    +ND+P+F+T A T +NVA
Sbjct: 123 FLIQVE-PKDPESFPFALIGNKVDDVANRKVSANKATNWCKANNDIPHFETSAKTAQNVA 181

Query: 264 IYVWDQLQRIMEKPQLLHEVKILET 338
               +  ++ + +     E+ I +T
Sbjct: 182 AAFMEIAKKAVMRDTQDDEIYIPDT 206


>UniRef50_A3LY22 Cluster: Predicted protein; n=1; Pichia
           stipitis|Rep: Predicted protein - Pichia stipitis
           (Yeast)
          Length = 531

 Score = 31.1 bits (67), Expect = 6.3
 Identities = 13/42 (30%), Positives = 23/42 (54%)
 Frame = +3

Query: 201 KNLDNDVPYFKTMASTTENVAIYVWDQLQRIMEKPQLLHEVK 326
           K +D ++ Y++   S TE  +    DQ+  I E   +LH+V+
Sbjct: 27  KEIDGEIQYWQKRVSQTETTSEAARDQINDIFELADVLHDVQ 68


>UniRef50_A1RYM7 Cluster: Extracellular solute-binding protein,
           family 3 precursor; n=1; Thermofilum pendens Hrk 5|Rep:
           Extracellular solute-binding protein, family 3 precursor
           - Thermofilum pendens (strain Hrk 5)
          Length = 279

 Score = 31.1 bits (67), Expect = 6.3
 Identities = 16/34 (47%), Positives = 17/34 (50%)
 Frame = -1

Query: 265 IATFSVVLAIVLKYGTSLSKFLWSSGSRXAVFMY 164
           IA F  V A+ L  GTSL  FLW S S      Y
Sbjct: 11  IAKFLAVFAVGLLLGTSLGYFLWHSASTTQTVSY 44


>UniRef50_UPI000023CB0A Cluster: hypothetical protein FG02847.1;
           n=1; Gibberella zeae PH-1|Rep: hypothetical protein
           FG02847.1 - Gibberella zeae PH-1
          Length = 1398

 Score = 30.7 bits (66), Expect = 8.3
 Identities = 19/67 (28%), Positives = 31/67 (46%)
 Frame = -3

Query: 302 FFHYSLKLVPDIYCDIFCSTCHSFEVWNIII*ILMVEWFQXGCFYVFLEVSYIHHHTXLR 123
           F+H S + +     D+   T +   V+N++I  +     + G F+ F   SY+       
Sbjct: 535 FYHQSAQAIASYIIDLPYKTANMI-VFNLLIYFMSNLRREAGSFFFFCLTSYLTTLVMSC 593

Query: 122 IYRTLYC 102
           IYRTL C
Sbjct: 594 IYRTLAC 600


>UniRef50_Q54JY9 Cluster: Putative uncharacterized protein; n=1;
           Dictyostelium discoideum AX4|Rep: Putative
           uncharacterized protein - Dictyostelium discoideum AX4
          Length = 706

 Score = 30.7 bits (66), Expect = 8.3
 Identities = 19/56 (33%), Positives = 29/56 (51%)
 Frame = +3

Query: 192 LDHKNLDNDVPYFKTMASTTENVAIYVWDQLQRIMEKPQLLHEVKILETEKNHVVY 359
           L+ K+ DN  PY   +  +T+    ++W + Q+I EK QL      LE + N  VY
Sbjct: 308 LNLKDADNKTPYELALTRSTDPCIAFLW-KAQKI-EKKQLTKGKSSLELQDNANVY 361


>UniRef50_Q4YBM6 Cluster: Putative uncharacterized protein; n=6;
            Plasmodium (Vinckeia)|Rep: Putative uncharacterized
            protein - Plasmodium berghei
          Length = 1594

 Score = 30.7 bits (66), Expect = 8.3
 Identities = 14/48 (29%), Positives = 24/48 (50%)
 Frame = +3

Query: 159  KKYIKTAXLEPLDHKNLDNDVPYFKTMASTTENVAIYVWDQLQRIMEK 302
            K Y+K    E +   N    + YF+ M  T +N AI +++ +Q I  +
Sbjct: 1313 KNYLKLNSYENIISHNEKTGLNYFEYMCKTNDNDAIIIFNNIQNIFRR 1360


>UniRef50_Q4Q2S9 Cluster: Putative uncharacterized protein; n=3;
           Leishmania|Rep: Putative uncharacterized protein -
           Leishmania major
          Length = 910

 Score = 30.7 bits (66), Expect = 8.3
 Identities = 12/39 (30%), Positives = 23/39 (58%)
 Frame = +3

Query: 237 MASTTENVAIYVWDQLQRIMEKPQLLHEVKILETEKNHV 353
           + S   +V   + D L  +ME+ ++L  +++LET K H+
Sbjct: 447 LGSAVHSVETSIMDDLSIVMERTEVLAALRVLETVKQHL 485


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 312,729,081
Number of Sequences: 1657284
Number of extensions: 5555570
Number of successful extensions: 13587
Number of sequences better than 10.0: 57
Number of HSP's better than 10.0 without gapping: 13338
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 13570
length of database: 575,637,011
effective HSP length: 90
effective length of database: 426,481,451
effective search space used: 12794443530
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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