Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= bmte10b05
(716 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q7PCV3 Cluster: ENSANGP00000031808; n=9; Endopterygota|... 303 3e-81
UniRef50_P45376 Cluster: Aldose reductase; n=21; Bilateria|Rep: ... 292 7e-78
UniRef50_P15121 Cluster: Aldose reductase; n=72; Eumetazoa|Rep: ... 283 2e-75
UniRef50_Q2LZ66 Cluster: GA19341-PA; n=2; Endopterygota|Rep: GA1... 281 1e-74
UniRef50_Q9VTL0 Cluster: CG6083-PA; n=4; Diptera|Rep: CG6083-PA ... 276 3e-73
UniRef50_Q8CI22 Cluster: 2310005E10Rik protein; n=30; Tetrapoda|... 274 2e-72
UniRef50_UPI00015B56A2 Cluster: PREDICTED: similar to GA10458-PA... 258 1e-67
UniRef50_P14550 Cluster: Alcohol dehydrogenase [NADP+]; n=44; Bi... 256 4e-67
UniRef50_Q9NAI5 Cluster: Putative uncharacterized protein; n=3; ... 250 3e-65
UniRef50_Q7QK25 Cluster: ENSANGP00000019775; n=2; Anopheles gamb... 249 6e-65
UniRef50_Q17DN0 Cluster: Aldo-keto reductase; n=5; Culicidae|Rep... 245 7e-64
UniRef50_Q96JD6 Cluster: Aldo-keto reductase family 1 member C-l... 235 1e-60
UniRef50_A7SIT3 Cluster: Predicted protein; n=1; Nematostella ve... 234 1e-60
UniRef50_UPI00015B56A3 Cluster: PREDICTED: similar to aldo-keto ... 233 3e-60
UniRef50_Q0VGY1 Cluster: 3-alpha-hydroxysteroid dehydrogenase; n... 232 6e-60
UniRef50_UPI0000588153 Cluster: PREDICTED: hypothetical protein;... 232 7e-60
UniRef50_Q54B70 Cluster: Aldehyde reductase; n=2; Dictyostelium ... 230 3e-59
UniRef50_A5KSS3 Cluster: Aldehyde reductase; n=1; candidate divi... 229 5e-59
UniRef50_Q0PGJ6 Cluster: Aldo-keto reductase; n=32; Magnoliophyt... 227 3e-58
UniRef50_A2QBD7 Cluster: Catalytic activity: an alcohol + NADP(+... 225 6e-58
UniRef50_Q2S340 Cluster: Aldehyde reductase; n=10; Bacteria|Rep:... 224 1e-57
UniRef50_UPI000065D0BD Cluster: Homolog of Homo sapiens "AKR1B1 ... 224 2e-57
UniRef50_UPI0000E4A7CE Cluster: PREDICTED: similar to LOC553452 ... 223 3e-57
UniRef50_Q8K023 Cluster: Aldo-keto reductase family 1 member C18... 223 5e-57
UniRef50_Q7JVH6 Cluster: LD24696p; n=2; Sophophora|Rep: LD24696p... 222 6e-57
UniRef50_Q5BKE9 Cluster: LOC594893 protein; n=5; Xenopus tropica... 221 2e-56
UniRef50_Q8VC28 Cluster: Aldo-keto reductase family 1 member C13... 217 2e-55
UniRef50_Q7QVQ9 Cluster: GLP_302_44328_45269; n=1; Giardia lambl... 213 3e-54
UniRef50_P51857 Cluster: 3-oxo-5-beta-steroid 4-dehydrogenase (E... 213 4e-54
UniRef50_Q55FL3 Cluster: Aldo-keto reductase; n=2; Dictyostelium... 212 8e-54
UniRef50_Q2V420 Cluster: Uncharacterized protein At2g37770.1; n=... 209 5e-53
UniRef50_UPI0000498F1F Cluster: oxidoreductase, aldo/keto reduct... 208 1e-52
UniRef50_Q10494 Cluster: Probable oxidoreductase C26F1.07; n=2; ... 208 1e-52
UniRef50_P27800 Cluster: Aldehyde reductase 1; n=18; root|Rep: A... 208 1e-52
UniRef50_Q0IBY6 Cluster: Alcohol dehydrogenase; n=2; Chroococcal... 207 2e-52
UniRef50_A3U9Y0 Cluster: Aldehyde reductase; n=5; Bacteroidetes|... 207 2e-52
UniRef50_A2R6Z3 Cluster: Catalytic activity: an alcohol + NADP(+... 206 4e-52
UniRef50_Q96UH3 Cluster: Aldehyde reductase; n=13; Pezizomycotin... 204 2e-51
UniRef50_UPI0000D9A956 Cluster: PREDICTED: similar to aldo-keto ... 198 8e-50
UniRef50_P38715 Cluster: NADPH-dependent aldose reductase GRE3; ... 198 8e-50
UniRef50_Q7ZWA4 Cluster: Zgc:56622; n=6; cellular organisms|Rep:... 198 1e-49
UniRef50_Q22352 Cluster: Putative uncharacterized protein T08H10... 197 3e-49
UniRef50_Q7ZA52 Cluster: Aldose reductase; n=6; Pezizomycotina|R... 195 8e-49
UniRef50_A4RQH8 Cluster: Predicted protein; n=2; Ostreococcus|Re... 195 1e-48
UniRef50_Q9VHX4 Cluster: CG2767-PA; n=4; Endopterygota|Rep: CG27... 195 1e-48
UniRef50_Q8SSK6 Cluster: ALDOSE REDUCTASE; n=1; Encephalitozoon ... 193 3e-48
UniRef50_Q2UGR1 Cluster: Aldo/keto reductase family proteins; n=... 193 3e-48
UniRef50_UPI0000E45E29 Cluster: PREDICTED: similar to aldose red... 192 6e-48
UniRef50_Q96JD6-2 Cluster: Isoform 2 of Q96JD6 ; n=4; Catarrhini... 190 4e-47
UniRef50_A7PNI3 Cluster: Chromosome chr1 scaffold_22, whole geno... 190 4e-47
UniRef50_Q9Y020 Cluster: 3-dehydroecdysone 3beta-reductase precu... 190 4e-47
UniRef50_A2EYY6 Cluster: Oxidoreductase, aldo/keto reductase fam... 189 5e-47
UniRef50_Q1YPE5 Cluster: Aldehyde reductase; n=7; Bacteria|Rep: ... 189 7e-47
UniRef50_Q16K66 Cluster: Aldo-keto reductase; n=2; Aedes aegypti... 188 1e-46
UniRef50_A2QVE5 Cluster: Similarity: shows similarity to several... 188 2e-46
UniRef50_Q9U2J5 Cluster: Putative uncharacterized protein; n=2; ... 186 5e-46
UniRef50_UPI0000499B0E Cluster: oxidoreductase, aldo/keto reduct... 186 6e-46
UniRef50_Q1IN88 Cluster: Aldehyde reductase; n=5; Bacteria|Rep: ... 185 8e-46
UniRef50_Q4PAT5 Cluster: Putative uncharacterized protein; n=1; ... 185 8e-46
UniRef50_Q6TY50 Cluster: Reductase 2; n=10; Magnoliophyta|Rep: R... 184 3e-45
UniRef50_Q5KI95 Cluster: Aldo-keto reductase, putative; n=14; Di... 184 3e-45
UniRef50_Q41399 Cluster: Chalcone reductase; n=4; eudicotyledons... 183 4e-45
UniRef50_A2EHN6 Cluster: Oxidoreductase, aldo/keto reductase fam... 182 6e-45
UniRef50_Q17G72 Cluster: Aldo-keto reductase; n=9; Endopterygota... 181 1e-44
UniRef50_P26690 Cluster: NAD(P)H-dependent 6'-deoxychalcone synt... 180 2e-44
UniRef50_Q01J82 Cluster: OSIGBa0152K17.5 protein; n=28; Magnolio... 180 3e-44
UniRef50_A2FPE2 Cluster: Oxidoreductase, aldo/keto reductase fam... 180 3e-44
UniRef50_Q7PLK6 Cluster: CG40064-PA; n=1; Drosophila melanogaste... 180 4e-44
UniRef50_Q6RZX1 Cluster: Gld1; n=22; Pezizomycotina|Rep: Gld1 - ... 180 4e-44
UniRef50_P23901 Cluster: Aldose reductase; n=9; Poaceae|Rep: Ald... 178 1e-43
UniRef50_Q6CFG7 Cluster: Yarrowia lipolytica chromosome B of str... 177 2e-43
UniRef50_UPI00015B4B22 Cluster: PREDICTED: similar to GA15457-PA... 177 2e-43
UniRef50_A5E082 Cluster: GCY protein; n=4; Saccharomycetales|Rep... 177 3e-43
UniRef50_Q03TW0 Cluster: Aldo/keto reductase of diketogulonate r... 176 5e-43
UniRef50_Q0CLQ2 Cluster: Putative uncharacterized protein; n=1; ... 176 5e-43
UniRef50_A1D4E3 Cluster: D-xylose reductase (Xyl1), putative; n=... 176 5e-43
UniRef50_P38115 Cluster: D-arabinose dehydrogenase [NAD(P)+] hea... 176 5e-43
UniRef50_Q1U9L6 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 175 7e-43
UniRef50_Q9FJK0 Cluster: Aldose reductase-like protein; n=3; cor... 175 9e-43
UniRef50_A6ESC0 Cluster: ARA1; n=1; unidentified eubacterium SCB... 174 2e-42
UniRef50_Q8WRT0 Cluster: 3-dehydrecdysone 3b-reductase; n=1; Tri... 174 2e-42
UniRef50_P22045 Cluster: Probable reductase; n=101; cellular org... 174 2e-42
UniRef50_UPI000023D0F1 Cluster: hypothetical protein FG03517.1; ... 173 4e-42
UniRef50_P14065 Cluster: Protein GCY; n=13; Saccharomycetales|Re... 173 4e-42
UniRef50_Q8J0K1 Cluster: 4-dihydromethyltrisporate dehydrogenase... 171 2e-41
UniRef50_Q05KR9 Cluster: Benzil reductase; n=5; Bacillales|Rep: ... 170 3e-41
UniRef50_UPI0000519CC2 Cluster: PREDICTED: similar to CG2767-PA;... 169 6e-41
UniRef50_Q7PM68 Cluster: ENSANGP00000014386; n=1; Anopheles gamb... 169 8e-41
UniRef50_Q6C2L0 Cluster: Yarrowia lipolytica chromosome F of str... 168 1e-40
UniRef50_P28475 Cluster: NADP-dependent D-sorbitol-6-phosphate d... 168 1e-40
UniRef50_Q8F1G4 Cluster: Aldehyde reductase; n=8; Bacteria|Rep: ... 167 2e-40
UniRef50_Q41E86 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 167 2e-40
UniRef50_A6W8E7 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 167 2e-40
UniRef50_UPI00015B40FA Cluster: PREDICTED: similar to CG2767-PA;... 167 3e-40
UniRef50_Q23320 Cluster: Putative uncharacterized protein; n=4; ... 167 3e-40
UniRef50_Q9HGY0 Cluster: Glycerol dehydrogenase; n=8; Saccharomy... 167 3e-40
UniRef50_Q68ST9 Cluster: Reductase AKOR2; n=2; Pleurotus djamor|... 166 6e-40
UniRef50_Q7R2T6 Cluster: GLP_291_56367_57278; n=1; Giardia lambl... 165 7e-40
UniRef50_A6RKL9 Cluster: Putative uncharacterized protein; n=3; ... 165 7e-40
UniRef50_UPI0000D56CE5 Cluster: PREDICTED: similar to CG6084-PA,... 165 1e-39
UniRef50_Q03PG5 Cluster: Aldo/keto reductase of diketogulonate r... 165 1e-39
UniRef50_A2QL02 Cluster: Putative frameshift; n=1; Aspergillus n... 165 1e-39
UniRef50_Q5HR31 Cluster: Oxidoreductase, aldo/keto reductase fam... 164 2e-39
UniRef50_A3C1Z7 Cluster: Putative uncharacterized protein; n=2; ... 164 2e-39
UniRef50_Q4Q5N9 Cluster: Prostaglandin f synthase, putative; n=7... 163 5e-39
UniRef50_Q5T2L2 Cluster: Aldo-keto reductase family 1 member C-l... 163 5e-39
UniRef50_Q838E0 Cluster: Oxidoreductase, aldo/keto reductase fam... 162 7e-39
UniRef50_UPI00015B5BD7 Cluster: PREDICTED: similar to aldo-keto ... 162 9e-39
UniRef50_UPI00015B4912 Cluster: PREDICTED: similar to aldo-keto ... 161 2e-38
UniRef50_A3LTU8 Cluster: D-arabinose dehydrogenase; n=5; Sacchar... 161 2e-38
UniRef50_A7CWF9 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: ... 160 3e-38
UniRef50_Q01HB5 Cluster: OSIGBa0136O08-OSIGBa0153H12.9 protein; ... 159 5e-38
UniRef50_Q4PDR0 Cluster: Putative uncharacterized protein; n=1; ... 159 5e-38
UniRef50_Q9ZBW7 Cluster: Putative oxidoreductase; n=2; Actinomyc... 159 6e-38
UniRef50_Q7G764 Cluster: Probable NAD(P)H-dependent oxidoreducta... 159 6e-38
UniRef50_UPI00006CD296 Cluster: oxidoreductase, aldo/keto reduct... 158 1e-37
UniRef50_Q7N0E4 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 158 1e-37
UniRef50_Q968S3 Cluster: Aldoketoreductase-like protein; n=1; Or... 158 1e-37
UniRef50_Q7G765 Cluster: Probable NAD(P)H-dependent oxidoreducta... 157 3e-37
UniRef50_Q4FY75 Cluster: Aldo-keto reductase-like protein; n=5; ... 157 3e-37
UniRef50_Q4P4P1 Cluster: Putative uncharacterized protein; n=1; ... 155 8e-37
UniRef50_A2QB88 Cluster: Contig An01c0460, complete genome. prec... 155 1e-36
UniRef50_Q5FK98 Cluster: Oxidoreductase; n=8; Lactobacillales|Re... 152 7e-36
UniRef50_A6LZ55 Cluster: 2,5-didehydrogluconate reductase; n=1; ... 152 7e-36
UniRef50_A6WDZ5 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:... 151 1e-35
UniRef50_P06632 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 149 7e-35
UniRef50_Q1VRG6 Cluster: YvgN; n=1; Psychroflexus torquis ATCC 7... 147 3e-34
UniRef50_Q24C22 Cluster: Oxidoreductase, aldo/keto reductase fam... 147 3e-34
UniRef50_Q4PHK0 Cluster: Putative uncharacterized protein; n=1; ... 147 3e-34
UniRef50_Q7NB44 Cluster: ARA1; n=3; Firmicutes|Rep: ARA1 - Mycop... 146 4e-34
UniRef50_A0JX62 Cluster: 2,5-didehydrogluconate reductase; n=9; ... 146 4e-34
UniRef50_Q88SL1 Cluster: Oxidoreductase; n=51; Lactobacillales|R... 146 5e-34
UniRef50_A6NPD6 Cluster: Putative uncharacterized protein; n=3; ... 145 8e-34
UniRef50_Q5FT75 Cluster: Putative 2,5-diketo-D-gluconic acid red... 145 1e-33
UniRef50_Q6NII7 Cluster: Putative oxidoreductase; n=2; Corynebac... 144 1e-33
UniRef50_Q18483 Cluster: Putative uncharacterized protein; n=2; ... 144 1e-33
UniRef50_Q9X0A2 Cluster: Oxidoreductase, aldo/keto reductase fam... 144 2e-33
UniRef50_Q03XK0 Cluster: Aldo/keto reductase of diketogulonate r... 144 2e-33
UniRef50_Q83N50 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 144 3e-33
UniRef50_A7CUW0 Cluster: 2,5-didehydrogluconate reductase; n=6; ... 144 3e-33
UniRef50_A0JRJ6 Cluster: Aldo/keto reductase; n=2; Micrococcinea... 144 3e-33
UniRef50_Q3E9M9 Cluster: Uncharacterized protein At5g01670.2; n=... 144 3e-33
UniRef50_UPI00006CCCD7 Cluster: oxidoreductase, aldo/keto reduct... 143 3e-33
UniRef50_Q5TNP1 Cluster: ENSANGP00000029046; n=2; Culicidae|Rep:... 143 3e-33
UniRef50_A7ALH6 Cluster: Putative uncharacterized protein; n=1; ... 143 4e-33
UniRef50_P47137 Cluster: Probable oxidoreductase YJR096W; n=8; S... 143 4e-33
UniRef50_A5ZYE6 Cluster: Putative uncharacterized protein; n=1; ... 142 6e-33
UniRef50_A5VK30 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 142 6e-33
UniRef50_A2UAH0 Cluster: Aldo/keto reductase; n=1; Bacillus coag... 141 1e-32
UniRef50_Q8ZI40 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 141 1e-32
UniRef50_Q235V6 Cluster: Oxidoreductase, aldo/keto reductase fam... 141 2e-32
UniRef50_Q2U219 Cluster: Aldo/keto reductase family proteins; n=... 140 2e-32
UniRef50_O13848 Cluster: NADH/NADPH dependent indole-3-acetaldeh... 140 2e-32
UniRef50_Q1DLF1 Cluster: Putative uncharacterized protein; n=1; ... 140 3e-32
UniRef50_UPI0000DB6EE9 Cluster: PREDICTED: similar to C35D10.6; ... 140 4e-32
UniRef50_Q28P63 Cluster: Aldo/keto reductase; n=4; Rhodobacterac... 140 4e-32
UniRef50_A7BA05 Cluster: Putative uncharacterized protein; n=1; ... 139 7e-32
UniRef50_Q17568 Cluster: Putative uncharacterized protein; n=1; ... 139 7e-32
UniRef50_Q929C8 Cluster: Lin2349 protein; n=12; Listeria|Rep: Li... 138 1e-31
UniRef50_Q1RFP0 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 138 1e-31
UniRef50_Q5FKI1 Cluster: Reductase-dehydrogenase; n=1; Lactobaci... 138 2e-31
UniRef50_Q17DN1 Cluster: Aldo-keto reductase; n=1; Aedes aegypti... 138 2e-31
UniRef50_Q5XJM7 Cluster: Zgc:101765; n=5; Eumetazoa|Rep: Zgc:101... 137 2e-31
UniRef50_Q7VG53 Cluster: Aldo-keto reductase; n=28; Bacteria|Rep... 137 3e-31
UniRef50_A5PDA8 Cluster: Putative oxidoreductase protein; n=1; E... 136 4e-31
UniRef50_Q6WGK4 Cluster: Aldose reductase; n=1; Pristionchus pac... 136 4e-31
UniRef50_Q4JX70 Cluster: Putative oxidoreductase; n=1; Corynebac... 136 5e-31
UniRef50_Q043M4 Cluster: Aldo/keto reductase of diketogulonate r... 136 5e-31
UniRef50_A3UJS6 Cluster: Oxidoreductase; n=3; Alphaproteobacteri... 136 5e-31
UniRef50_A7RRF6 Cluster: Predicted protein; n=2; Nematostella ve... 136 5e-31
UniRef50_Q5BLA6 Cluster: Zgc:110782; n=2; Danio rerio|Rep: Zgc:1... 136 7e-31
UniRef50_Q02198 Cluster: Morphine 6-dehydrogenase; n=5; Bacteria... 136 7e-31
UniRef50_Q8ET73 Cluster: 2,5-diketo-D-gluconate reductase; n=12;... 135 1e-30
UniRef50_A0JRJ3 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 135 1e-30
UniRef50_Q5V6N9 Cluster: Alcohol dehydrogenase; n=2; Halobacteri... 135 1e-30
UniRef50_Q9A2X8 Cluster: Oxidoreductase, aldo/keto reductase fam... 133 4e-30
UniRef50_Q11BF8 Cluster: Aldo/keto reductase; n=12; Bacteria|Rep... 133 4e-30
UniRef50_Q4WUF7 Cluster: Aldo-keto reductase, putative; n=3; Pez... 132 6e-30
UniRef50_Q88TV9 Cluster: Oxidoreductase; n=4; Lactobacillus|Rep:... 132 1e-29
UniRef50_Q568D7 Cluster: Zgc:110366; n=7; Euteleostomi|Rep: Zgc:... 131 1e-29
UniRef50_A1UEC5 Cluster: 2,5-didehydrogluconate reductase; n=20;... 131 1e-29
UniRef50_Q5UX52 Cluster: Oxidoreductase aldo/keto reductase fami... 131 1e-29
UniRef50_Q890A0 Cluster: Oxidoreductase; n=6; Lactobacillales|Re... 131 2e-29
UniRef50_Q5FLI5 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: ... 131 2e-29
UniRef50_O14088 Cluster: Xylose and arabinose reductase; n=1; Sc... 131 2e-29
UniRef50_A5AD50 Cluster: Putative uncharacterized protein; n=3; ... 130 3e-29
UniRef50_A6RMS0 Cluster: Putative uncharacterized protein; n=1; ... 130 3e-29
UniRef50_P82125 Cluster: 1,5-anhydro-D-fructose reductase; n=1; ... 106 3e-29
UniRef50_A7D761 Cluster: Aldo/keto reductase; n=2; Halobacteriac... 129 6e-29
UniRef50_Q54NR2 Cluster: Aldo-keto reductase; n=3; Dictyostelium... 128 1e-28
UniRef50_Q6F7K7 Cluster: 2,5-diketo-D-gluconate reductase; n=20;... 128 1e-28
UniRef50_A2RMU6 Cluster: Oxidoreductase, aldo/keto reductase fam... 128 1e-28
UniRef50_Q89JN4 Cluster: Oxidoreductase; n=8; Rhizobiales|Rep: O... 128 2e-28
UniRef50_Q6CEJ0 Cluster: Yarrowia lipolytica chromosome B of str... 128 2e-28
UniRef50_Q1Q8W8 Cluster: Aldo/keto reductase; n=1; Psychrobacter... 127 2e-28
UniRef50_A6SI80 Cluster: Putative uncharacterized protein; n=1; ... 127 3e-28
UniRef50_Q927E1 Cluster: Lin2848 protein; n=13; Listeria|Rep: Li... 126 4e-28
UniRef50_Q7M4N1 Cluster: Dihydrodiol dehydrogenase DD2; n=2; Hom... 77 4e-28
UniRef50_Q7WSY4 Cluster: Putative aldo-keto reductase; n=1; Prop... 126 5e-28
UniRef50_Q00XM4 Cluster: Aldo/keto reductase family proteins; n=... 126 5e-28
UniRef50_Q03X85 Cluster: Aldo/keto reductase of diketogulonate r... 125 1e-27
UniRef50_Q6U5V3 Cluster: Putative uncharacterized protein; n=1; ... 124 2e-27
UniRef50_Q15NA5 Cluster: Aldo/keto reductase; n=2; Gammaproteoba... 124 2e-27
UniRef50_Q8G7K9 Cluster: Dehydrogenase or reductase protein; n=4... 123 5e-27
UniRef50_A6VNW9 Cluster: Aldo/keto reductase precursor; n=1; Act... 123 5e-27
UniRef50_A7P424 Cluster: Chromosome chr1 scaffold_5, whole genom... 123 5e-27
UniRef50_Q9C1X5 Cluster: Xylose and arabinose reductase; n=1; Sc... 123 5e-27
UniRef50_Q4WP69 Cluster: Aldehyde reductase, putative; n=1; Aspe... 123 5e-27
UniRef50_UPI00006CA3CB Cluster: oxidoreductase, aldo/keto reduct... 122 7e-27
UniRef50_Q09632 Cluster: Probable oxidoreductase ZK1290.5; n=2; ... 122 7e-27
UniRef50_P70883 Cluster: AkrI; n=1; Butyrivibrio fibrisolvens|Re... 122 9e-27
UniRef50_A1CAM7 Cluster: Aldo-keto reductase, putative; n=9; Dik... 122 9e-27
UniRef50_P91997 Cluster: Putative uncharacterized protein; n=4; ... 122 1e-26
UniRef50_Q5V398 Cluster: Oxidoreductase aldo/keto reductase fami... 120 3e-26
UniRef50_Q572D2 Cluster: Aldo-keto reductase, putative; n=1; Phy... 120 5e-26
UniRef50_P15339 Cluster: 2,5-diketo-D-gluconic acid reductase B;... 120 5e-26
UniRef50_Q03U37 Cluster: Aldo/keto reductase of diketogulonate r... 119 6e-26
UniRef50_A7BES9 Cluster: Putative uncharacterized protein; n=1; ... 119 6e-26
UniRef50_Q8EUH6 Cluster: Oxidoreductase; n=1; Mycoplasma penetra... 119 8e-26
UniRef50_A3WP89 Cluster: Aldo/keto reductase; n=1; Idiomarina ba... 119 8e-26
UniRef50_Q9P734 Cluster: Related to 2, 5-diketo-D-gluconic acid ... 119 8e-26
UniRef50_Q9ZUJ6 Cluster: T2K10.1 protein; n=16; core eudicotyled... 118 2e-25
UniRef50_Q4PE96 Cluster: Putative uncharacterized protein; n=1; ... 118 2e-25
UniRef50_Q927P9 Cluster: Lin2739 protein; n=12; Bacteria|Rep: Li... 117 3e-25
UniRef50_Q1M4Z6 Cluster: Putative aldo-keto reductase/oxidase; n... 117 3e-25
UniRef50_Q7VHE1 Cluster: Putative uncharacterized protein; n=1; ... 116 4e-25
UniRef50_Q5KD52 Cluster: Oxidoreductase, putative; n=1; Filobasi... 116 4e-25
UniRef50_A3VHZ9 Cluster: Oxidoreductase; n=1; Rhodobacterales ba... 116 6e-25
UniRef50_A0L1A2 Cluster: Aldo/keto reductase; n=8; Gammaproteoba... 116 6e-25
UniRef50_A0AWM8 Cluster: Aldo/keto reductase; n=4; Actinomycetal... 116 6e-25
UniRef50_A5DRJ6 Cluster: Putative uncharacterized protein; n=4; ... 116 6e-25
UniRef50_Q5V663 Cluster: Aldehyde reductase; n=6; Halobacteriace... 116 6e-25
UniRef50_Q0SFM4 Cluster: Probable 2,5-didehydrogluconate reducta... 115 1e-24
UniRef50_Q4V008 Cluster: Oxidoreductase; n=4; Proteobacteria|Rep... 114 2e-24
UniRef50_A4YQ04 Cluster: 2,5-diketo-D-gluconate reductase B; n=1... 114 2e-24
UniRef50_Q5FK99 Cluster: Oxidoreductase aldo-keto reductase fami... 113 3e-24
UniRef50_Q4DJ59 Cluster: Aldo/keto reductase, putative; n=2; Try... 113 5e-24
UniRef50_A7TLC4 Cluster: Putative uncharacterized protein; n=1; ... 112 9e-24
UniRef50_Q5UYI9 Cluster: Oxidoreductase; n=1; Haloarcula marismo... 111 1e-23
UniRef50_Q5K8C5 Cluster: Aldo-keto reductase, putative; n=1; Fil... 111 2e-23
UniRef50_Q8Y463 Cluster: Lmo2592 protein; n=40; Bacteria|Rep: Lm... 111 2e-23
UniRef50_Q7XY49 Cluster: Mannose 6-phosphate reductase; n=1; Gri... 110 3e-23
UniRef50_A3VRL4 Cluster: Putative uncharacterized protein; n=1; ... 109 5e-23
UniRef50_Q21274 Cluster: Putative uncharacterized protein; n=1; ... 109 7e-23
UniRef50_Q5KKZ8 Cluster: Aldo-keto reductase, putative; n=2; Fil... 109 7e-23
UniRef50_Q9X265 Cluster: Oxidoreductase, aldo/keto reductase fam... 108 1e-22
UniRef50_Q0CK00 Cluster: Predicted protein; n=1; Aspergillus ter... 108 2e-22
UniRef50_Q5NLW3 Cluster: Putative oxidoreductase; n=1; Zymomonas... 107 4e-22
UniRef50_Q75E75 Cluster: ABL209Cp; n=1; Eremothecium gossypii|Re... 106 6e-22
UniRef50_A7SGW6 Cluster: Predicted protein; n=1; Nematostella ve... 105 8e-22
UniRef50_Q5B034 Cluster: Putative uncharacterized protein; n=1; ... 105 8e-22
UniRef50_A5BF24 Cluster: Putative uncharacterized protein; n=1; ... 105 1e-21
UniRef50_Q8ZH36 Cluster: 2,5-diketo-D-gluconic acid reductase B;... 104 3e-21
UniRef50_Q8EVT8 Cluster: Oxidoreductase-aldo/keto reductase fami... 103 6e-21
UniRef50_Q3CZS2 Cluster: Oxidoreductase, aldo/keto reductase fam... 103 6e-21
UniRef50_A3JU52 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 102 1e-20
UniRef50_Q9HM42 Cluster: Alcohol dehydrogenase related protein; ... 102 1e-20
UniRef50_Q6L139 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 102 1e-20
UniRef50_Q11B35 Cluster: Aldo/keto reductase; n=1; Mesorhizobium... 101 2e-20
UniRef50_A3T261 Cluster: Putative uncharacterized protein; n=1; ... 100 3e-20
UniRef50_Q013C5 Cluster: Glycerol dehydrogenase, putative; n=2; ... 100 3e-20
UniRef50_Q59Z55 Cluster: Potential aldo/keto reductase; n=6; Sac... 100 3e-20
UniRef50_A7D6Q0 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 100 3e-20
UniRef50_Q9P6D3 Cluster: Related to aldo-keto reductase YPR1; n=... 99 5e-20
UniRef50_Q5KCN9 Cluster: Putative uncharacterized protein; n=1; ... 99 5e-20
UniRef50_Q2H7A8 Cluster: Putative uncharacterized protein; n=1; ... 99 5e-20
UniRef50_UPI000023DF27 Cluster: hypothetical protein FG07276.1; ... 99 9e-20
UniRef50_Q07551 Cluster: NADPH-dependent alpha-keto amide reduct... 99 9e-20
UniRef50_Q64UK5 Cluster: Aldo/keto reductase family oxidoreducta... 98 2e-19
UniRef50_Q11DV1 Cluster: Aldo/keto reductase; n=10; Alphaproteob... 98 2e-19
UniRef50_Q8EVS8 Cluster: Oxidoreductase; n=1; Mycoplasma penetra... 97 3e-19
UniRef50_Q76L37 Cluster: Conjugated polyketone reductase C1; n=3... 97 4e-19
UniRef50_Q979I4 Cluster: Aldo / keto reductase; n=3; Archaea|Rep... 97 5e-19
UniRef50_Q2BBN7 Cluster: YvgN; n=1; Bacillus sp. NRRL B-14911|Re... 96 7e-19
UniRef50_A6QXT4 Cluster: Predicted protein; n=1; Ajellomyces cap... 96 7e-19
UniRef50_Q76L36 Cluster: Conjugated polyketone reductase C2; n=1... 95 1e-18
UniRef50_A4FEB9 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 95 2e-18
UniRef50_Q61U89 Cluster: Putative uncharacterized protein CBG054... 95 2e-18
UniRef50_A7D6I8 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 95 2e-18
UniRef50_Q0DHN0 Cluster: Os05g0456200 protein; n=2; Oryza sativa... 94 3e-18
UniRef50_Q4JCC1 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 94 4e-18
UniRef50_A6PR52 Cluster: Aldo/keto reductase; n=1; Victivallis v... 91 3e-17
UniRef50_A7D7K7 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 90 4e-17
UniRef50_A7RUA2 Cluster: Predicted protein; n=1; Nematostella ve... 89 8e-17
UniRef50_Q14LA8 Cluster: Putative aldo/keto reductase oxidoreduc... 89 1e-16
UniRef50_Q97U17 Cluster: Oxidoreductase, aldo/keto reductase fam... 89 1e-16
UniRef50_Q1PV10 Cluster: Putative uncharacterized protein; n=1; ... 88 2e-16
UniRef50_Q14LU6 Cluster: Putative aldo/keto reductase oxidoreduc... 88 2e-16
UniRef50_Q4P1G1 Cluster: Putative uncharacterized protein; n=1; ... 88 2e-16
UniRef50_Q68A33 Cluster: Aldo-keto reductase 1a; n=1; Ciona inte... 87 3e-16
UniRef50_Q4WI64 Cluster: Aldehyde reductase, putative; n=22; Pez... 87 3e-16
UniRef50_UPI00005A2CCB Cluster: PREDICTED: similar to Aldose red... 87 5e-16
UniRef50_Q4WF80 Cluster: Glycerol dehydrogenase (GCY1), putative... 87 5e-16
UniRef50_A3LWP0 Cluster: Aldo/keto reductase; n=7; Saccharomycet... 87 5e-16
UniRef50_Q2CAL9 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 86 7e-16
UniRef50_Q6CGE9 Cluster: Similar to sp|P47137 Saccharomyces cere... 85 2e-15
UniRef50_A3H9Y8 Cluster: Aldo/keto reductase; n=2; Caldivirga ma... 85 2e-15
UniRef50_A7EW94 Cluster: Putative uncharacterized protein; n=1; ... 84 3e-15
UniRef50_UPI000155CAC7 Cluster: PREDICTED: hypothetical protein;... 83 7e-15
UniRef50_Q2H1Q3 Cluster: Putative uncharacterized protein; n=1; ... 83 9e-15
UniRef50_Q9USV2 Cluster: Xylose and arabinose reductase; n=2; Sc... 82 1e-14
UniRef50_Q59ZT1 Cluster: Putative uncharacterized protein; n=1; ... 82 1e-14
UniRef50_Q4Q973 Cluster: Aldo/keto reductase, putative; n=3; Lei... 81 3e-14
UniRef50_Q16CS5 Cluster: 2,5-diketo-D-gluconic acid reductase B,... 81 4e-14
UniRef50_Q89RG2 Cluster: Aldo/keto reductase; n=11; Bacteria|Rep... 80 6e-14
UniRef50_A1RB46 Cluster: 2,5-diketo-D-gluconate reductase; n=1; ... 80 6e-14
UniRef50_UPI000038E317 Cluster: hypothetical protein Faci_030017... 79 8e-14
UniRef50_Q5V1M9 Cluster: Oxidoreductase aldo/keto reductase fami... 79 1e-13
UniRef50_Q9V2P1 Cluster: Myo-inositol degradation; n=5; Archaea|... 78 2e-13
UniRef50_Q5B5R6 Cluster: Putative uncharacterized protein; n=1; ... 78 2e-13
UniRef50_P91021 Cluster: Putative uncharacterized protein; n=1; ... 76 8e-13
UniRef50_Q97UV9 Cluster: Oxidoreductase; n=1; Sulfolobus solfata... 76 1e-12
UniRef50_UPI00005F9591 Cluster: COG0656: Aldo/keto reductases, r... 73 9e-12
UniRef50_A6R5B4 Cluster: NAD(P)H-dependent D-xylose reductase; n... 73 9e-12
UniRef50_P76234 Cluster: Uncharacterized protein yeaE; n=39; Bac... 72 1e-11
UniRef50_Q8DK16 Cluster: Tlr1054 protein; n=6; Cyanobacteria|Rep... 71 3e-11
UniRef50_Q97V56 Cluster: Dehydrogenase; n=8; Thermoprotei|Rep: D... 71 3e-11
UniRef50_Q8EUX1 Cluster: Aldo/keto reductase family oxidoreducta... 71 4e-11
UniRef50_Q5KKC5 Cluster: Putative uncharacterized protein; n=2; ... 71 4e-11
UniRef50_A7LSN6 Cluster: Putative uncharacterized protein; n=3; ... 70 5e-11
UniRef50_A4R217 Cluster: Putative uncharacterized protein; n=1; ... 70 7e-11
UniRef50_A2G4I3 Cluster: Oxidoreductase, aldo/keto reductase fam... 68 2e-10
UniRef50_Q7NK63 Cluster: Gll1617 protein; n=1; Gloeobacter viola... 68 3e-10
UniRef50_Q5FHT2 Cluster: Aldehyde reductase; n=4; Lactobacillus|... 67 4e-10
UniRef50_A6RYK4 Cluster: Putative uncharacterized protein; n=1; ... 67 5e-10
UniRef50_Q64W37 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 66 6e-10
UniRef50_Q6CWB9 Cluster: Similarities with sp|Q12458 Saccharomyc... 66 1e-09
UniRef50_Q03BE0 Cluster: Aldo/keto reductase family enzyme; n=5;... 65 2e-09
UniRef50_UPI000023DA24 Cluster: hypothetical protein FG10036.1; ... 64 2e-09
UniRef50_A7RPK2 Cluster: Predicted protein; n=1; Nematostella ve... 64 3e-09
UniRef50_A5BYJ4 Cluster: Putative uncharacterized protein; n=1; ... 63 6e-09
UniRef50_Q55FL2 Cluster: Putative uncharacterized protein; n=1; ... 63 6e-09
UniRef50_A7HEV1 Cluster: Aldo/keto reductase; n=13; Bacteria|Rep... 63 8e-09
UniRef50_Q8PN61 Cluster: Oxidoreductase; n=5; Proteobacteria|Rep... 62 1e-08
UniRef50_Q5ZTU6 Cluster: D-xylose reductase III; n=5; Legionella... 62 1e-08
UniRef50_Q18903 Cluster: Putative uncharacterized protein C56G3.... 62 1e-08
UniRef50_UPI0001556575 Cluster: PREDICTED: similar to Aldo-keto ... 62 2e-08
UniRef50_Q21EY6 Cluster: Aldo/keto reductase; n=1; Saccharophagu... 62 2e-08
UniRef50_Q0UQ60 Cluster: Putative uncharacterized protein; n=1; ... 62 2e-08
UniRef50_Q660Z5 Cluster: Aldose reductase, putative; n=3; Borrel... 61 2e-08
UniRef50_Q0GU15 Cluster: ORF28; n=3; Bacteria|Rep: ORF28 - Lacto... 61 2e-08
UniRef50_Q4Q5X1 Cluster: Aldehyde reductase, putative; n=75; cel... 61 2e-08
UniRef50_A1S0T5 Cluster: Aldo/keto reductase; n=2; Thermoprotei|... 61 2e-08
UniRef50_A7PNT1 Cluster: Chromosome chr8 scaffold_23, whole geno... 61 3e-08
UniRef50_Q8ZU65 Cluster: Aldo-keto reductase, putative; n=4; The... 61 3e-08
UniRef50_A3DNU7 Cluster: Aldo/keto reductase; n=3; Desulfurococc... 61 3e-08
UniRef50_UPI0000DAE567 Cluster: hypothetical protein Rgryl_01000... 60 7e-08
UniRef50_A6QVW8 Cluster: Predicted protein; n=1; Ajellomyces cap... 60 7e-08
UniRef50_A1CLD1 Cluster: Gamma-cysteine synthetase regulatory su... 60 7e-08
UniRef50_A3U5K6 Cluster: Oxidoreductase, aldo/keto reductase fam... 58 2e-07
UniRef50_A6BIJ0 Cluster: Putative uncharacterized protein; n=1; ... 58 2e-07
UniRef50_UPI00015BB020 Cluster: aldo/keto reductase; n=1; Ignico... 58 3e-07
UniRef50_Q8YAN3 Cluster: Lmo0084 protein; n=11; Listeria monocyt... 58 3e-07
UniRef50_Q87SA8 Cluster: Oxidoreductase Tas, aldo/keto reductase... 57 4e-07
UniRef50_Q5BC40 Cluster: Putative uncharacterized protein; n=1; ... 57 5e-07
UniRef50_Q6GIV4 Cluster: Aldo/keto reductase family protein; n=1... 56 7e-07
UniRef50_Q2JHT1 Cluster: Aldo/keto reductase Tas; n=25; cellular... 56 7e-07
UniRef50_Q1IQ78 Cluster: Aldo/keto reductase; n=1; Acidobacteria... 56 9e-07
UniRef50_Q03UP2 Cluster: Aryl-alcohol dehydrogenase family enzym... 56 9e-07
UniRef50_Q03UP0 Cluster: Aryl-alcohol dehydrogenase family enzym... 56 9e-07
UniRef50_Q93KW0 Cluster: Putative oxidoreductase; n=1; Streptomy... 56 1e-06
UniRef50_Q55ML8 Cluster: Putative uncharacterized protein; n=2; ... 56 1e-06
UniRef50_A6W292 Cluster: Aldo/keto reductase; n=9; Bacteria|Rep:... 55 2e-06
UniRef50_A4IJ00 Cluster: LOC548351 protein; n=1; Xenopus tropica... 55 2e-06
UniRef50_Q81RN9 Cluster: Oxidoreductase, aldo/keto reductase fam... 55 2e-06
UniRef50_A0RYR0 Cluster: Oxidoreductase; n=2; cellular organisms... 55 2e-06
UniRef50_Q94A68 Cluster: Uncharacterized oxidoreductase At1g0669... 54 3e-06
UniRef50_P0A9T5 Cluster: Protein tas; n=88; Bacteria|Rep: Protei... 54 3e-06
UniRef50_A7B2Y7 Cluster: Putative uncharacterized protein; n=1; ... 54 4e-06
UniRef50_A2WWZ1 Cluster: Putative uncharacterized protein; n=1; ... 54 4e-06
UniRef50_A3H7G3 Cluster: Aldo/keto reductase; n=2; Caldivirga ma... 54 4e-06
UniRef50_A0LJ47 Cluster: Aldo/keto reductase; n=1; Syntrophobact... 53 6e-06
UniRef50_Q60BI7 Cluster: Oxidoreductase, aldo/keto reductase fam... 53 8e-06
UniRef50_Q1U6R9 Cluster: Aldo/keto reductase; n=25; Bacilli|Rep:... 53 8e-06
UniRef50_UPI0000611A01 Cluster: PREDICTED: similar to MGC80525 p... 52 1e-05
UniRef50_P46905 Cluster: Uncharacterized oxidoreductase yccK; n=... 52 1e-05
UniRef50_A2UBC7 Cluster: Aldo/keto reductase; n=3; cellular orga... 52 2e-05
UniRef50_A2FJN9 Cluster: Putative uncharacterized protein; n=4; ... 52 2e-05
UniRef50_Q88SS2 Cluster: Oxidoreductase; n=13; Firmicutes|Rep: O... 51 2e-05
UniRef50_Q2BBT9 Cluster: Probable oxidoreductase protein; n=2; B... 51 2e-05
UniRef50_A1RA11 Cluster: Oxidoreductase, aldo/keto reductase fam... 51 2e-05
UniRef50_A7T149 Cluster: Predicted protein; n=1; Nematostella ve... 51 3e-05
UniRef50_Q872E2 Cluster: Related to gamma-glutamylcysteine synth... 51 3e-05
UniRef50_Q3ZWR6 Cluster: Oxidoreductase, aldo reductase; n=3; De... 50 4e-05
UniRef50_A0Y7Y8 Cluster: Aldo/keto reductase; n=1; marine gamma ... 50 4e-05
UniRef50_Q9X0R5 Cluster: Oxidoreductase, aldo/keto reductase fam... 50 6e-05
UniRef50_Q1VSU3 Cluster: Aryl-alcohol dehydrogenase; n=1; Psychr... 50 6e-05
UniRef50_A6SUJ2 Cluster: Uncharacterized conserved protein; n=2;... 50 6e-05
UniRef50_Q9ZUX0 Cluster: Expressed protein; n=11; cellular organ... 50 6e-05
UniRef50_Q09D95 Cluster: Ydhf chain A; n=1; Stigmatella aurantia... 50 8e-05
UniRef50_A6X3I0 Cluster: Aldo/keto reductase; n=3; Bacteria|Rep:... 50 8e-05
UniRef50_A4M6J9 Cluster: Aldo/keto reductase; n=1; Petrotoga mob... 50 8e-05
UniRef50_Q33BE9 Cluster: Aldo/keto reductase, putative; n=1; Ory... 50 8e-05
UniRef50_A0QHX8 Cluster: General stress protein 69; n=2; Mycobac... 49 1e-04
UniRef50_Q9SAC2 Cluster: T16B5.5 protein; n=23; Magnoliophyta|Re... 49 1e-04
UniRef50_Q5V3K3 Cluster: Oxidoreductase aldo/keto reductase fami... 49 1e-04
UniRef50_P80874 Cluster: General stress protein 69; n=16; cellul... 49 1e-04
UniRef50_A5FAZ9 Cluster: Aldo/keto reductase; n=1; Flavobacteriu... 48 2e-04
UniRef50_Q9C2J8 Cluster: Related to D-xylose reductase II, III p... 48 2e-04
UniRef50_Q21F89 Cluster: Aldo/keto reductase; n=1; Saccharophagu... 48 2e-04
UniRef50_Q966L2 Cluster: Putative uncharacterized protein; n=2; ... 48 2e-04
UniRef50_Q8UIN0 Cluster: Oxidoreductase; n=3; Alphaproteobacteri... 48 3e-04
UniRef50_Q3WEJ4 Cluster: Aldo/keto reductase; n=9; Bacteria|Rep:... 48 3e-04
UniRef50_A6AKU1 Cluster: Aldo/keto reductase; n=2; Gammaproteoba... 48 3e-04
UniRef50_A0YC40 Cluster: Putative uncharacterized protein; n=1; ... 48 3e-04
UniRef50_Q84M96 Cluster: At1g60680; n=19; cellular organisms|Rep... 48 3e-04
UniRef50_Q5KQ01 Cluster: Pyridoxal reductase, putative; n=2; Fil... 48 3e-04
UniRef50_Q82JL9 Cluster: Putative oxidoreductase; n=2; Streptomy... 47 4e-04
UniRef50_Q2JB77 Cluster: Aldo/keto reductase; n=1; Frankia sp. C... 47 5e-04
UniRef50_Q41CR8 Cluster: Aldo/keto reductase; n=1; Exiguobacteri... 47 5e-04
UniRef50_Q03I00 Cluster: Aryl-alcohol dehydrogenase related enzy... 47 5e-04
UniRef50_Q016B0 Cluster: COG0667: Predicted oxidoreductases; n=4... 47 5e-04
UniRef50_Q8ID61 Cluster: Aldo-keto reductase, putative; n=6; Pla... 47 5e-04
UniRef50_A0RWV1 Cluster: Oxidoreductase; n=4; Thermoprotei|Rep: ... 40 7e-04
UniRef50_UPI0000D9C1BD Cluster: PREDICTED: similar to aldo-keto ... 46 7e-04
UniRef50_UPI0000447325 Cluster: PREDICTED: similar to aldo-keto ... 46 7e-04
UniRef50_Q986W6 Cluster: Mlr7180 protein; n=4; Alphaproteobacter... 46 7e-04
UniRef50_Q2SL81 Cluster: Predicted oxidoreductase; n=10; Bacteri... 46 7e-04
UniRef50_P93818 Cluster: F19P19.12 protein; n=4; Arabidopsis tha... 46 7e-04
UniRef50_Q6L0T3 Cluster: Oxidoreductase; n=2; Thermoplasmatales|... 46 7e-04
UniRef50_Q0AL14 Cluster: Aldo/keto reductase; n=1; Maricaulis ma... 46 0.001
UniRef50_A0K1H5 Cluster: Aldo/keto reductase; n=6; Actinomycetal... 46 0.001
UniRef50_UPI000023DAA9 Cluster: hypothetical protein FG00321.1; ... 46 0.001
UniRef50_Q64UJ6 Cluster: Putative aldo/keto reductase; n=3; Bact... 46 0.001
UniRef50_Q31SB1 Cluster: Putative uncharacterized protein; n=2; ... 46 0.001
UniRef50_Q8Y5Q1 Cluster: Lmo2005 protein; n=34; cellular organis... 45 0.002
UniRef50_A7HAM2 Cluster: Aldo/keto reductase; n=9; cellular orga... 45 0.002
UniRef50_A1RAH7 Cluster: Oxidoreductase, aldo/keto reductase fam... 45 0.002
UniRef50_A7D5V2 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 45 0.002
UniRef50_Q8EVP7 Cluster: Putative oxidoreductase; n=3; Bacteria|... 45 0.002
UniRef50_Q391C9 Cluster: Aldo/keto reductase; n=10; Proteobacter... 45 0.002
UniRef50_Q08NK7 Cluster: Aldo/keto reductase; n=1; Stigmatella a... 45 0.002
UniRef50_Q2FGN2 Cluster: Oxidoreductase, aldo/keto reductase fam... 44 0.003
UniRef50_O94246 Cluster: Glutamate-cysteine ligase regulatory su... 44 0.003
UniRef50_A7BLU0 Cluster: Aldo/keto reductase family; n=1; Beggia... 44 0.004
UniRef50_A1ZPI5 Cluster: Oxidoreductase; n=1; Microscilla marina... 44 0.004
UniRef50_A1B5W4 Cluster: Aldo/keto reductase; n=1; Paracoccus de... 44 0.004
UniRef50_Q5KPU6 Cluster: Putative uncharacterized protein; n=2; ... 44 0.004
UniRef50_Q8ZXA1 Cluster: Aldo-keto reductase family protein; n=3... 44 0.004
UniRef50_P40690 Cluster: Aldo-keto reductase; n=4; Piroplasmida|... 44 0.004
UniRef50_Q7D001 Cluster: AGR_C_2023p; n=14; Proteobacteria|Rep: ... 44 0.005
UniRef50_Q6NKP1 Cluster: At5g53580; n=18; cellular organisms|Rep... 44 0.005
UniRef50_A7PU13 Cluster: Chromosome chr7 scaffold_31, whole geno... 44 0.005
UniRef50_Q6TRS1 Cluster: Oxidoreductase; n=1; Ustilago maydis|Re... 44 0.005
UniRef50_Q97UJ7 Cluster: Oxidoreductase; n=4; Archaea|Rep: Oxido... 44 0.005
UniRef50_P42972 Cluster: Uncharacterized oxidoreductase ycsN; n=... 44 0.005
UniRef50_Q1FHF4 Cluster: Aldo/keto reductase:4Fe-4S ferredoxin, ... 43 0.007
UniRef50_A6WAE5 Cluster: Aldo/keto reductase; n=1; Kineococcus r... 43 0.007
UniRef50_A0YSM3 Cluster: Probable oxidoreductase; n=1; Lyngbya s... 43 0.007
UniRef50_A6XQ31 Cluster: Putative uncharacterized protein; n=1; ... 43 0.007
UniRef50_A6SJ74 Cluster: Putative uncharacterized protein; n=1; ... 43 0.007
UniRef50_A3LSR5 Cluster: D-threo-aldose 1-dehydrogenase; n=5; Sa... 43 0.007
UniRef50_A2BKU2 Cluster: Universally conserved protein; n=2; Des... 43 0.007
UniRef50_P49249 Cluster: IN2-2 protein; n=6; Magnoliophyta|Rep: ... 43 0.007
UniRef50_UPI0000DB6B5C Cluster: PREDICTED: similar to glutamate-... 43 0.009
UniRef50_A6LWU9 Cluster: Aldo/keto reductase; n=3; Clostridium|R... 43 0.009
UniRef50_Q17N98 Cluster: Gamma-glutamylcysteine synthetase, puta... 43 0.009
UniRef50_Q8PVL5 Cluster: Oxidoreductase, ALDO/KETO reductase fam... 43 0.009
UniRef50_Q2NEM6 Cluster: Putative oxidoreductase; n=1; Methanosp... 43 0.009
UniRef50_Q9QWA5 Cluster: Aldose reductase; n=5; Euarchontoglires... 42 0.011
UniRef50_Q8G7F7 Cluster: Possible oxidoreductase of the aldo/ket... 42 0.011
UniRef50_Q2SPS9 Cluster: Predicted oxidoreductase; n=5; Gammapro... 42 0.011
UniRef50_Q2AI49 Cluster: Aldo/keto reductase; n=1; Halothermothr... 42 0.011
UniRef50_Q096Q3 Cluster: Oxidoreductase, aldo reductase; n=1; St... 42 0.011
UniRef50_Q04TM6 Cluster: Aryl-alcohol dehydrogenase-related oxid... 42 0.011
UniRef50_A5VEK4 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:... 42 0.011
UniRef50_A0ZMD5 Cluster: Tas; n=1; Nodularia spumigena CCY 9414|... 42 0.011
UniRef50_Q2NGB6 Cluster: Predicted oxidoreductase; n=1; Methanos... 42 0.011
UniRef50_Q97RL3 Cluster: Oxidoreductase, aldo/keto reductase fam... 42 0.015
UniRef50_Q11BU4 Cluster: Aldo/keto reductase; n=11; Proteobacter... 42 0.015
UniRef50_A6VXX8 Cluster: Aldo/keto reductase; n=2; Marinomonas|R... 42 0.015
UniRef50_A5Z5D1 Cluster: Putative uncharacterized protein; n=4; ... 42 0.015
UniRef50_A0VU33 Cluster: Aldo/keto reductase; n=1; Dinoroseobact... 42 0.015
UniRef50_A0QWF1 Cluster: Aldo/keto reductase; n=1; Mycobacterium... 42 0.015
UniRef50_Q28R03 Cluster: Aldo/keto reductase; n=4; Alphaproteoba... 42 0.020
UniRef50_A1SGJ5 Cluster: Aldo/keto reductase precursor; n=1; Noc... 42 0.020
UniRef50_A0Q648 Cluster: Aldo/keto reductase family protein; n=1... 42 0.020
UniRef50_Q2H7Q3 Cluster: Putative uncharacterized protein; n=1; ... 42 0.020
UniRef50_Q9YBV5 Cluster: Putative uncharacterized protein; n=1; ... 42 0.020
UniRef50_Q98IA6 Cluster: Aryl-alcohol dehydrogenase; n=1; Mesorh... 41 0.027
UniRef50_Q88TP1 Cluster: Oxidoreductase; n=3; Bacteria|Rep: Oxid... 41 0.027
UniRef50_A4A767 Cluster: Aldo/keto reductase/Endoribonuclease L-... 41 0.027
UniRef50_A0LHW7 Cluster: Aldo/keto reductase precursor; n=1; Syn... 41 0.027
UniRef50_A3H9H5 Cluster: Aldo/keto reductase; n=2; Archaea|Rep: ... 41 0.027
UniRef50_Q88T82 Cluster: Oxidoreductase; n=18; Bacteria|Rep: Oxi... 41 0.035
UniRef50_Q3I1P2 Cluster: Aldo-keto oxidoreductase; n=6; Bacteria... 41 0.035
UniRef50_Q034L5 Cluster: Aryl-alcohol dehydrogenase related enzy... 41 0.035
UniRef50_A5GMY9 Cluster: Aldo/keto reductase family protein; n=2... 41 0.035
UniRef50_Q4QEB9 Cluster: Protein kinase, putative; n=3; Leishman... 41 0.035
UniRef50_Q2UT23 Cluster: Voltage-gated shaker-like K+ channel; n... 41 0.035
UniRef50_A6S357 Cluster: Putative uncharacterized protein; n=2; ... 41 0.035
UniRef50_P49261 Cluster: Rho beta-crystallin; n=1; Lepidodactylu... 41 0.035
UniRef50_Q8G5I8 Cluster: Possible oxidoreductase in aldo-keto re... 40 0.046
UniRef50_Q08P32 Cluster: Aldo/keto reductase; n=3; Proteobacteri... 40 0.046
UniRef50_A6C9W8 Cluster: Aldo/keto reductase; n=2; Planctomyceta... 40 0.046
UniRef50_A0JZE6 Cluster: Aldo/keto reductase; n=1; Arthrobacter ... 40 0.046
UniRef50_Q6WN58 Cluster: Glutamate-cysteine ligase modifier subu... 40 0.046
UniRef50_P82810 Cluster: Morphine 6-dehydrogenase; n=1; Oryctola... 40 0.046
UniRef50_Q4TC86 Cluster: Chromosome undetermined SCAF7044, whole... 40 0.061
UniRef50_Q9PCQ5 Cluster: Sugar-phosphate dehydrogenase; n=23; Ba... 40 0.061
>UniRef50_Q7PCV3 Cluster: ENSANGP00000031808; n=9;
Endopterygota|Rep: ENSANGP00000031808 - Anopheles
gambiae str. PEST
Length = 316
Score = 303 bits (743), Expect = 3e-81
Identities = 137/214 (64%), Positives = 160/214 (74%), Gaps = 1/214 (0%)
Frame = +1
Query: 73 VPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 252
VP F N P+ GLGTW S PG+V QAVKDAID+GYRHIDCA+VY NE EVGE I +
Sbjct: 6 VPNAIFKNGNSIPMFGLGTWNSPPGQVAQAVKDAIDVGYRHIDCAHVYQNEHEVGEGIAA 65
Query: 253 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGS 432
KI EGVV REDLF+TSKLWNTFHRPDLV GA + TL NL + YLDLYLIHWP Y+E
Sbjct: 66 KIAEGVVKREDLFVTSKLWNTFHRPDLVEGACKTTLQNLKLDYLDLYLIHWPVGYQEGTE 125
Query: 433 LFPTDQSGK-IQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVV 609
LFP GK FSD DYVDTW ME LV GLV++IGVSNFN+KQ++R+L A + P
Sbjct: 126 LFPMGPDGKTFLFSDADYVDTWPEMEKLVDAGLVRNIGVSNFNAKQVQRVLDVARIPPAT 185
Query: 610 NQVECHPYLNQKRLKEFCEARGVKITAYSPLGSP 711
NQ+ECHPYL+Q ++ FC +G+ +TAYSPLGSP
Sbjct: 186 NQIECHPYLHQSKITTFCAEKGIIVTAYSPLGSP 219
>UniRef50_P45376 Cluster: Aldose reductase; n=21; Bilateria|Rep:
Aldose reductase - Mus musculus (Mouse)
Length = 316
Score = 292 bits (716), Expect = 7e-78
Identities = 134/213 (62%), Positives = 161/213 (75%), Gaps = 2/213 (0%)
Frame = +1
Query: 82 VEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 261
+E NN K P LGLGTWKS PG+VT+AVK AID+GYRHIDCA VY NEKEVG A+ K+K
Sbjct: 5 LELNNGTKMPTLGLGTWKSPPGQVTEAVKVAIDLGYRHIDCAQVYQNEKEVGVALQEKLK 64
Query: 262 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 441
E VV R+DLFI SKLW TFH +V+GA Q+TL +L + YLDLYLIHWP +K FP
Sbjct: 65 EQVVKRQDLFIVSKLWCTFHDKSMVKGAFQKTLSDLQLDYLDLYLIHWPTGFKPGPDYFP 124
Query: 442 TDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATV--KPVVNQ 615
D SG + SD D+VDTW AME LV EGLVK+IGVSNFN Q+ER+L + KP VNQ
Sbjct: 125 LDASGNVIPSDTDFVDTWTAMEQLVDEGLVKTIGVSNFNPLQIERILNKPGLKYKPAVNQ 184
Query: 616 VECHPYLNQKRLKEFCEARGVKITAYSPLGSPD 714
+ECHPYL Q++L E+C ++G+ +TAYSPLGSPD
Sbjct: 185 IECHPYLTQEKLIEYCHSKGIVVTAYSPLGSPD 217
>UniRef50_P15121 Cluster: Aldose reductase; n=72; Eumetazoa|Rep:
Aldose reductase - Homo sapiens (Human)
Length = 316
Score = 283 bits (695), Expect = 2e-75
Identities = 128/210 (60%), Positives = 160/210 (76%), Gaps = 2/210 (0%)
Frame = +1
Query: 91 NNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 270
NN K PILGLGTWKS PG+VT+AVK AID+GYRHIDCA+VY NE EVG AI K++E V
Sbjct: 8 NNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQV 67
Query: 271 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQ 450
V RE+LFI SKLW T+H LV+GA Q+TL +L + YLDLYLIHWP +K FP D+
Sbjct: 68 VKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDE 127
Query: 451 SGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATV--KPVVNQVEC 624
SG + SD + +DTW AME LV EGLVK+IG+SNFN Q+E +L + KP VNQ+EC
Sbjct: 128 SGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQIEC 187
Query: 625 HPYLNQKRLKEFCEARGVKITAYSPLGSPD 714
HPYL Q++L ++C+++G+ +TAYSPLGSPD
Sbjct: 188 HPYLTQEKLIQYCQSKGIVVTAYSPLGSPD 217
>UniRef50_Q2LZ66 Cluster: GA19341-PA; n=2; Endopterygota|Rep:
GA19341-PA - Drosophila pseudoobscura (Fruit fly)
Length = 315
Score = 281 bits (689), Expect = 1e-74
Identities = 129/214 (60%), Positives = 158/214 (73%), Gaps = 1/214 (0%)
Frame = +1
Query: 70 SVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAIT 249
S P ++ P++GLGTW+S P V QAVKDAIDIGYRH DCA++YGNE VG AI
Sbjct: 2 STPSFLLSSGRNMPMVGLGTWRSPPEVVAQAVKDAIDIGYRHFDCAHIYGNELHVGVAIR 61
Query: 250 SKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDG 429
KI+EG+VTR++LFITSKLWNTFH+P+LVR A + +L NL + YLDLYL+HWP AYK
Sbjct: 62 EKIQEGLVTRDELFITSKLWNTFHKPELVRAACETSLRNLGIDYLDLYLMHWPMAYKSGD 121
Query: 430 SLFPT-DQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPV 606
+L+PT +GK F D+DY+DTWKAME LV GLV +IGVSNFN KQ+ RLL A +KPV
Sbjct: 122 NLYPTCPDTGKAVFEDIDYLDTWKAMEDLVDSGLVNAIGVSNFNEKQINRLLCLAKLKPV 181
Query: 607 VNQVECHPYLNQKRLKEFCEARGVKITAYSPLGS 708
+ Q+ECHPYL QK L C + +TAYS LGS
Sbjct: 182 MLQIECHPYLRQKSLITLCYDNAIGVTAYSSLGS 215
>UniRef50_Q9VTL0 Cluster: CG6083-PA; n=4; Diptera|Rep: CG6083-PA -
Drosophila melanogaster (Fruit fly)
Length = 322
Score = 276 bits (677), Expect = 3e-73
Identities = 129/215 (60%), Positives = 160/215 (74%), Gaps = 2/215 (0%)
Frame = +1
Query: 70 SVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAIT 249
S P +N P+LGLGTW+S P VTQAVKDAIDIGYRH DCA++YGNE +VG A+
Sbjct: 2 STPNFLLSNGKNMPMLGLGTWRSPPEVVTQAVKDAIDIGYRHFDCAHIYGNEAQVGAALR 61
Query: 250 SKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKE-D 426
K+ EGVVTR++LFITSKLWNT H+PDLVR A + ++ NL V+YL+LYL+HWP AYK
Sbjct: 62 EKMDEGVVTRDELFITSKLWNTHHKPDLVRPACETSIRNLGVKYLNLYLMHWPMAYKSGS 121
Query: 427 GSLFPT-DQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKP 603
+L+PT + K F D+DYVDTW+AME LV EGL ++IGVSNFN +Q+ RLL A +KP
Sbjct: 122 DNLYPTCPDTNKAAFEDIDYVDTWRAMENLVDEGLCQAIGVSNFNEQQMNRLLSVAKLKP 181
Query: 604 VVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGS 708
VV Q+ECHPYL+QK L C + +TAYS LGS
Sbjct: 182 VVLQIECHPYLSQKPLITLCYDNAIAVTAYSCLGS 216
>UniRef50_Q8CI22 Cluster: 2310005E10Rik protein; n=30;
Tetrapoda|Rep: 2310005E10Rik protein - Mus musculus
(Mouse)
Length = 316
Score = 274 bits (671), Expect = 2e-72
Identities = 128/214 (59%), Positives = 153/214 (71%), Gaps = 2/214 (0%)
Frame = +1
Query: 79 FVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 258
FV K PI+GLGTWKS P +V +AVK AID GYRHIDCAYVY NE EVGEAI KI
Sbjct: 4 FVTLLTGAKMPIVGLGTWKSPPAKVREAVKVAIDAGYRHIDCAYVYQNESEVGEAIQEKI 63
Query: 259 KEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLF 438
+E V REDLFI SKLW+TF LV+ A Q TL +L + YLDLYLIHWPQ ++
Sbjct: 64 QEKAVKREDLFIVSKLWSTFFEKSLVKKAFQNTLSDLKLDYLDLYLIHWPQGFQSGNVFL 123
Query: 439 PTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATV--KPVVN 612
PTD G I S ++D W+AME LV +GLVK++GVSNFN Q+ERLL + KPV N
Sbjct: 124 PTDDKGSILSSKYTFLDAWEAMEELVDQGLVKALGVSNFNHFQIERLLNKPGLKHKPVTN 183
Query: 613 QVECHPYLNQKRLKEFCEARGVKITAYSPLGSPD 714
QVECHPYL Q++L ++C ++G+ ITAYSPLGSPD
Sbjct: 184 QVECHPYLTQEKLTQYCHSKGITITAYSPLGSPD 217
>UniRef50_UPI00015B56A2 Cluster: PREDICTED: similar to GA10458-PA;
n=2; Nasonia vitripennis|Rep: PREDICTED: similar to
GA10458-PA - Nasonia vitripennis
Length = 569
Score = 258 bits (631), Expect = 1e-67
Identities = 115/213 (53%), Positives = 155/213 (72%)
Frame = +1
Query: 73 VPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 252
VP V FN+ K P++GLGT+ SKPGEV +AVK AI++GYRH+D A+ Y NEKE+G AI
Sbjct: 3 VPTVTFNDGYKMPMIGLGTFLSKPGEVAEAVKYAIEVGYRHVDTAFFYENEKEIGSAIRE 62
Query: 253 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGS 432
KI +G + RED+F+T+KLW H+ D V A +++L+NL Y+DL+L+HWP A+K +
Sbjct: 63 KINDGTIKREDIFVTTKLWCNSHKEDEVVPACKKSLENLGFDYIDLFLVHWPFAFKSGDA 122
Query: 433 LFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVN 612
L P D +GKI+FSD DY++TWK ME ++GL +SIG+SNFNS+Q+ RLL A +KPV N
Sbjct: 123 LTPRDAAGKIEFSDTDYLETWKGMEECKRQGLARSIGLSNFNSEQIARLLSSAKIKPVNN 182
Query: 613 QVECHPYLNQKRLKEFCEARGVKITAYSPLGSP 711
QVE LNQK L EFC+ + +T +SPLG P
Sbjct: 183 QVEVTMNLNQKPLIEFCKKHEITVTGFSPLGRP 215
Score = 188 bits (458), Expect = 1e-46
Identities = 92/176 (52%), Positives = 120/176 (68%), Gaps = 1/176 (0%)
Frame = +1
Query: 187 YRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDN 366
YRHID AY+Y NEK +G AI KIK+G V REDLF+T+KL H+ V A +++L++
Sbjct: 301 YRHIDTAYLYDNEKYIGNAIREKIKDGTVKREDLFVTTKLSYYAHKESEVVPACKQSLND 360
Query: 367 LNVQYLDLYLIHWP-QAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIG 543
L + Y+DLYLIHWP + Y + SGK+ SD DY++TWK ME ++GL +SIG
Sbjct: 361 LGLDYIDLYLIHWPIRRYFRHNK----NASGKLLLSDTDYLETWKGMEECKRQGLARSIG 416
Query: 544 VSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSP 711
VSNFNS+Q+ RLL+ A +KPV NQVE LNQK L EFC+ + +T YSPLG P
Sbjct: 417 VSNFNSEQITRLLEAAKIKPVNNQVEVSLKLNQKALIEFCKKHDITVTGYSPLGRP 472
>UniRef50_P14550 Cluster: Alcohol dehydrogenase [NADP+]; n=44;
Bilateria|Rep: Alcohol dehydrogenase [NADP+] - Homo
sapiens (Human)
Length = 325
Score = 256 bits (627), Expect = 4e-67
Identities = 113/205 (55%), Positives = 154/205 (75%), Gaps = 1/205 (0%)
Frame = +1
Query: 103 KCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEG-VVTR 279
K P++GLGTWKS+PG+V AVK A+ +GYRHIDCA +YGNE E+GEA+ + G V R
Sbjct: 13 KMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPGKAVPR 72
Query: 280 EDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGK 459
E+LF+TSKLWNT H P+ V AL++TL +L ++YLDLYL+HWP A++ + FP + G
Sbjct: 73 EELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADGT 132
Query: 460 IQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLN 639
I + Y +TWKA+E LV +GLV+++G+SNFNS+Q++ +L A+V+P V QVECHPYL
Sbjct: 133 ICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLA 192
Query: 640 QKRLKEFCEARGVKITAYSPLGSPD 714
Q L C+ARG+++TAYSPLGS D
Sbjct: 193 QNELIAHCQARGLEVTAYSPLGSSD 217
>UniRef50_Q9NAI5 Cluster: Putative uncharacterized protein; n=3;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 316
Score = 250 bits (611), Expect = 3e-65
Identities = 110/213 (51%), Positives = 146/213 (68%)
Frame = +1
Query: 73 VPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 252
V ++ N+ P +GLGTW+SKPGEV A+K A+ GYRHIDCA+VY N+KEVGEA+
Sbjct: 2 VQSLKLNSGYSIPAIGLGTWQSKPGEVAAAIKTAVAAGYRHIDCAHVYQNQKEVGEALKE 61
Query: 253 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGS 432
+ EG V RE+LFITSK+WNTFH + L +L + Y+DL LIHWPQ Y E
Sbjct: 62 ILDEGKVKREELFITSKVWNTFHSEAKAHENIDIILSDLQLSYVDLMLIHWPQGYAEGAE 121
Query: 433 LFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVN 612
LFP ++GK+++SDVDY++TWKA E K G +SIG+SNF Q++R+ A VKP
Sbjct: 122 LFPAGENGKMRYSDVDYLETWKAFEAAQKAGKCRSIGLSNFTHSQIQRVWDAAEVKPACL 181
Query: 613 QVECHPYLNQKRLKEFCEARGVKITAYSPLGSP 711
QVE HPY Q +L+EFC+ +G+ + YSPLG+P
Sbjct: 182 QVELHPYFTQVKLREFCKEKGIVVVGYSPLGNP 214
>UniRef50_Q7QK25 Cluster: ENSANGP00000019775; n=2; Anopheles gambiae
str. PEST|Rep: ENSANGP00000019775 - Anopheles gambiae
str. PEST
Length = 319
Score = 249 bits (609), Expect = 6e-65
Identities = 116/220 (52%), Positives = 159/220 (72%), Gaps = 5/220 (2%)
Frame = +1
Query: 67 SSVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAI 246
+ VP V F+N + P+LG GT+ ++ G+ + VK AID+GYRHID A++Y NE E+G+AI
Sbjct: 3 TQVPTVRFSNGYEIPVLGYGTYLAQKGQCVELVKKAIDLGYRHIDTAFLYENEVEIGQAI 62
Query: 247 TSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKED 426
KI EGV+ RED+F+T+KLWNTFH P V A + + D L++ Y+DL+L+H P +
Sbjct: 63 RDKIAEGVIRREDVFVTTKLWNTFHDPQHVEEAFRRSFDMLDIGYIDLFLMHSPMGVQFS 122
Query: 427 G----SLFPTDQSGKIQFSDVDYVDTWKAMEPLVKE-GLVKSIGVSNFNSKQLERLLQHA 591
G + P D +G + FSDVDYV+TWKAME LV G V+SIG+SNFNS+Q+ER+LQ A
Sbjct: 123 GYEYADMQPKDAAGNMLFSDVDYVETWKAMEKLVTAGGRVRSIGLSNFNSEQIERILQIA 182
Query: 592 TVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSP 711
TVKPV NQVE +P +Q++L FC+ARG+ +TAY P+G P
Sbjct: 183 TVKPVNNQVEANPGYDQRKLIAFCQARGITVTAYGPMGRP 222
>UniRef50_Q17DN0 Cluster: Aldo-keto reductase; n=5; Culicidae|Rep:
Aldo-keto reductase - Aedes aegypti (Yellowfever
mosquito)
Length = 324
Score = 245 bits (600), Expect = 7e-64
Identities = 121/217 (55%), Positives = 152/217 (70%), Gaps = 4/217 (1%)
Frame = +1
Query: 73 VPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 252
+P V+ NN L+ P +GLGT SK E +AV AID G+RHID AY Y NE VG AI +
Sbjct: 6 IPTVKLNNGLEMPAIGLGTSMSKGDECCKAVMTAIDEGFRHIDTAYNYRNEDVVGRAIRA 65
Query: 253 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDG- 429
KI+EGVVTRE+LF+T+KLWNTFH PD V A ++L++L + Y+DL+LIH P Y+ +G
Sbjct: 66 KIEEGVVTREELFVTTKLWNTFHHPDHVPMAFGKSLEHLGLDYVDLFLIHMPFGYEFNGW 125
Query: 430 ---SLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVK 600
P D +G + SD DYVDTWKAME L++ G V SIGVSNFNS+QLER+L + VK
Sbjct: 126 DPEKRTPLDDNGNVLCSDDDYVDTWKAMEKLLESGRVHSIGVSNFNSEQLERILANCRVK 185
Query: 601 PVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSP 711
PV NQVEC +NQK L EFC R + +TA+SP G P
Sbjct: 186 PVTNQVECSARINQKLLIEFCMERDIVVTAHSPFGRP 222
>UniRef50_Q96JD6 Cluster: Aldo-keto reductase family 1 member C-like
protein 2; n=37; Euteleostomi|Rep: Aldo-keto reductase
family 1 member C-like protein 2 - Homo sapiens (Human)
Length = 320
Score = 235 bits (574), Expect = 1e-60
Identities = 118/220 (53%), Positives = 145/220 (65%), Gaps = 21/220 (9%)
Frame = +1
Query: 109 PILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 288
P +GL +WK+ PG+VT+AVK+AID GYRH DCAY Y NE+EVG I KIKEG V REDL
Sbjct: 5 PAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDL 64
Query: 289 FITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKED--------GSL--- 435
FI +KLW T H+ LV A +++L L + YLDLYLIHWP +K L
Sbjct: 65 FIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSFC 124
Query: 436 --------FPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHA 591
P D+S + SD D++DTW+AME LV GLVK+IGVSNFN +QLERLL
Sbjct: 125 LSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKP 184
Query: 592 TV--KPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLG 705
+ KP+ NQ+ECHPYL QK L FC++R V +TAY PLG
Sbjct: 185 GLRFKPLTNQIECHPYLTQKNLISFCQSRDVSVTAYRPLG 224
>UniRef50_A7SIT3 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 323
Score = 234 bits (573), Expect = 1e-60
Identities = 111/211 (52%), Positives = 148/211 (70%)
Frame = +1
Query: 79 FVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 258
F + N P + LGTW+S EV AV+ AI++GYRHIDCA +YGNE E+GEA++ +
Sbjct: 7 FCKLNTGASIPAMALGTWQSSKEEVGNAVRLAIELGYRHIDCAEIYGNEGEIGEALSEVL 66
Query: 259 KEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLF 438
EG V RE+LF+TSKLW H PD V A Q TL NL + YLDLYLIH P A+K+ L
Sbjct: 67 TEGKVKREELFVTSKLWCDSHHPDDVLPACQATLKNLQLDYLDLYLIHIPVAFKKGVRLP 126
Query: 439 PTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQV 618
+ G I ++ +TW+AME LV +GL K+IGVSNF+ K+L +LL+ A++ P NQV
Sbjct: 127 HSIAEGIIGYTPEGVQNTWQAMEGLVAKGLCKAIGVSNFSVKRLNKLLETASIVPACNQV 186
Query: 619 ECHPYLNQKRLKEFCEARGVKITAYSPLGSP 711
E HPYL Q++LKEFC+++G+ +TAYSPLG+P
Sbjct: 187 ELHPYLPQEKLKEFCDSKGILLTAYSPLGNP 217
>UniRef50_UPI00015B56A3 Cluster: PREDICTED: similar to aldo-keto
reductase; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to aldo-keto reductase - Nasonia vitripennis
Length = 321
Score = 233 bits (570), Expect = 3e-60
Identities = 105/205 (51%), Positives = 142/205 (69%), Gaps = 2/205 (0%)
Frame = +1
Query: 103 KCPILGLGTWK--SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVT 276
K P+LGLGTW+ + P EV AVK AID GYRH DCA YGNE E+G+AI KI +GVV
Sbjct: 15 KVPVLGLGTWQGGNDPDEVENAVKLAIDAGYRHFDCASFYGNEAEIGKAIQEKIDQGVVK 74
Query: 277 REDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSG 456
REDLF+ +K+WN + +LV A + +L L + Y+DLYL+HWP +Y
Sbjct: 75 REDLFVVTKVWNDERKQELVVAACKRSLKKLGLGYIDLYLVHWPFSYPILYQYIVLPTYN 134
Query: 457 KIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYL 636
+ +VDY++TW+ ME +K GL +SIGVSNFNS+QL RLL+ A++KPV+NQ+E H L
Sbjct: 135 AVTLDEVDYIETWRGMEECIKLGLTRSIGVSNFNSQQLTRLLESASIKPVMNQIELHINL 194
Query: 637 NQKRLKEFCEARGVKITAYSPLGSP 711
NQK+L+EFC ++ + +T YSP G+P
Sbjct: 195 NQKKLREFCASKSIAVTGYSPFGAP 219
>UniRef50_Q0VGY1 Cluster: 3-alpha-hydroxysteroid dehydrogenase;
n=13; Tetrapoda|Rep: 3-alpha-hydroxysteroid
dehydrogenase - Xenopus tropicalis (Western clawed frog)
(Silurana tropicalis)
Length = 324
Score = 232 bits (568), Expect = 6e-60
Identities = 109/215 (50%), Positives = 147/215 (68%), Gaps = 5/215 (2%)
Frame = +1
Query: 79 FVEFNNELKCPILGLGTW---KSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAIT 249
+VE N+ K P++G GT+ K + K AID+GYRHIDCA++YGNE+EVG AI
Sbjct: 8 YVELNDGHKMPVIGFGTYAPPKFPKSLAEEGTKVAIDVGYRHIDCAFLYGNEEEVGRAIR 67
Query: 250 SKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDG 429
+KI +G V RED+F T KLW+T H P+ VR AL+++L +L + Y+DL++IH P +K
Sbjct: 68 AKIADGTVKREDVFYTGKLWSTSHTPERVRPALEKSLKDLQLDYMDLFIIHMPMEFKPGD 127
Query: 430 SLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATV--KP 603
LFP D++GK + + D DTWKA+E GLV+SIGVSNFN KQLE +L + KP
Sbjct: 128 DLFPADENGKFIYHNTDLRDTWKALEKCKDAGLVRSIGVSNFNHKQLELILNMPGLKYKP 187
Query: 604 VVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGS 708
V NQVECH YLNQ +L EFC+++ + + YS LGS
Sbjct: 188 VCNQVECHVYLNQSKLLEFCKSKDIVLVGYSVLGS 222
>UniRef50_UPI0000588153 Cluster: PREDICTED: hypothetical protein;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 333
Score = 232 bits (567), Expect = 7e-60
Identities = 106/204 (51%), Positives = 141/204 (69%), Gaps = 2/204 (0%)
Frame = +1
Query: 109 PILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 288
P++GLGTWK K EV A+ A+D GYRH DCA +YGNEKEVG A+ ++ + RED+
Sbjct: 14 PLVGLGTWKLKADEVAGAIGAAVDAGYRHFDCALIYGNEKEVGVALREAMQRLGLKREDV 73
Query: 289 FITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGS--LFPTDQSGKI 462
FIT+K+WNTFH + V +L +L + Y+DLY++HWP ++ G +FP ++G I
Sbjct: 74 FITTKVWNTFHAKEDVAECFNRSLTDLQLDYIDLYIMHWPLGFQNLGPTVMFPRTETGDI 133
Query: 463 QFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQ 642
+SDV Y++TW AME LVK G KS+G+SNFNSKQL+ +LQH+TV P V QVE HP+L Q
Sbjct: 134 VYSDVHYLETWSAMEDLVKTGKCKSLGLSNFNSKQLDDVLQHSTVPPSVLQVESHPFLPQ 193
Query: 643 KRLKEFCEARGVKITAYSPLGSPD 714
L FC R V ++AYSPLG D
Sbjct: 194 VELLNFCRERSVVVSAYSPLGCGD 217
>UniRef50_Q54B70 Cluster: Aldehyde reductase; n=2; Dictyostelium
discoideum|Rep: Aldehyde reductase - Dictyostelium
discoideum AX4
Length = 297
Score = 230 bits (562), Expect = 3e-59
Identities = 113/212 (53%), Positives = 147/212 (69%), Gaps = 1/212 (0%)
Frame = +1
Query: 76 PFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSK 255
P + ++ K P++G GTWK++ V +AV+ A+D GYRHIDCA VY NEKEVGEA T K
Sbjct: 3 PSFKLSSGHKIPLVGFGTWKAETTLVGKAVEVALDAGYRHIDCAAVYLNEKEVGEAFTKK 62
Query: 256 IK-EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGS 432
E V RED+FITSKLWNTFH+ + VR AL+ TL +L +QYLDLYL+HWP A++ +
Sbjct: 63 FTTEATVKREDVFITSKLWNTFHKKEHVRPALERTLSDLGLQYLDLYLVHWPVAFEYTSN 122
Query: 433 LFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVN 612
T SG Q V +TW+ ME LV GLVKSIG+SNFN + L +L +A +KP N
Sbjct: 123 DIQT--SGSTQ-EFVSIRETWEEMEKLVDAGLVKSIGLSNFNVQGLMEVLSYARIKPAAN 179
Query: 613 QVECHPYLNQKRLKEFCEARGVKITAYSPLGS 708
QVE HP+L+Q LK+FC+ + +TAYSPLG+
Sbjct: 180 QVELHPFLSQPELKKFCDKHNIHLTAYSPLGN 211
>UniRef50_A5KSS3 Cluster: Aldehyde reductase; n=1; candidate
division TM7 genomosp. GTL1|Rep: Aldehyde reductase -
candidate division TM7 genomosp. GTL1
Length = 299
Score = 229 bits (560), Expect = 5e-59
Identities = 107/207 (51%), Positives = 140/207 (67%)
Frame = +1
Query: 94 NELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVV 273
N+ P+LG GTW+ G V+ AI GYRHIDCA +YGNEKEVGE I I +GVV
Sbjct: 8 NKQTLPLLGYGTWELPTGTTADLVETAIKAGYRHIDCAMIYGNEKEVGEGIRRTIDQGVV 67
Query: 274 TREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQS 453
REDLF+TSKLWNT H V A ++TL++L + YLDLYLIHW A++ +L P D
Sbjct: 68 KREDLFVTSKLWNTDHAQVDVGVACRKTLNDLGLDYLDLYLIHWGVAFEHGDNLEPLDDD 127
Query: 454 GKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPY 633
G +FS + +TW+AME LV++GLVKS+GV+NF + L LL +A +KP V+Q+E HPY
Sbjct: 128 GVAKFSFISMKETWQAMEELVEQGLVKSMGVANFTAPMLLDLLSYAKIKPAVHQIELHPY 187
Query: 634 LNQKRLKEFCEARGVKITAYSPLGSPD 714
L Q L FC ++ + +TAYSP GS +
Sbjct: 188 LAQNDLVAFCYSQNIAVTAYSPFGSTE 214
>UniRef50_Q0PGJ6 Cluster: Aldo-keto reductase; n=32;
Magnoliophyta|Rep: Aldo-keto reductase - Arabidopsis
thaliana (Mouse-ear cress)
Length = 315
Score = 227 bits (554), Expect = 3e-58
Identities = 111/215 (51%), Positives = 145/215 (67%)
Frame = +1
Query: 67 SSVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAI 246
+++ F + N K P +GLGTW++ PG V AV A+ IGYRHIDCA +YGNEKE+G +
Sbjct: 3 NAITFFKLNTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGAVL 62
Query: 247 TSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKED 426
++ VV REDLFITSKLW T H P V AL TL +L ++Y+DLYLIHWP K+
Sbjct: 63 KKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKK- 121
Query: 427 GSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPV 606
GS+ ++ VD TWKAME L G ++IGVSNF++K+L LL+ A V P
Sbjct: 122 GSVGIKPEN----LLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVPPA 177
Query: 607 VNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSP 711
VNQVECHP Q +L+EFC+++GV ++AYSPLGSP
Sbjct: 178 VNQVECHPSWRQTKLQEFCKSKGVHLSAYSPLGSP 212
>UniRef50_A2QBD7 Cluster: Catalytic activity: an alcohol + NADP(+)
<=> an aldehyde + NADPH; n=4; Trichocomaceae|Rep:
Catalytic activity: an alcohol + NADP(+) <=> an aldehyde
+ NADPH - Aspergillus niger
Length = 323
Score = 225 bits (551), Expect = 6e-58
Identities = 109/215 (50%), Positives = 142/215 (66%)
Frame = +1
Query: 64 MSSVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEA 243
MS N K P +G GTW++KP EV AV+ A+ GYRHIDCA +Y NE EVG
Sbjct: 1 MSLPSHFTINTGAKIPAVGFGTWQAKPLEVENAVEVALREGYRHIDCAAIYRNETEVGNG 60
Query: 244 ITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKE 423
I K GV RE++FIT KLWNT H P+ V AL +TL +L V YLDLYL+HWP A+K
Sbjct: 61 IR---KSGV-PREEIFITGKLWNTKHAPEDVEPALDKTLQDLGVAYLDLYLMHWPCAFKG 116
Query: 424 DGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKP 603
FP + G +++DY+ T++AME L+ G V++IGVSNFN ++LE LL +V P
Sbjct: 117 GDKWFPLNDDGVFDLANIDYITTYRAMEKLLATGKVRAIGVSNFNIRRLEELLGQVSVVP 176
Query: 604 VVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGS 708
VNQ+E HPYL Q L +FC+++G+ I AYSPLG+
Sbjct: 177 AVNQIEAHPYLQQPDLLQFCQSKGILIEAYSPLGN 211
>UniRef50_Q2S340 Cluster: Aldehyde reductase; n=10; Bacteria|Rep:
Aldehyde reductase - Salinibacter ruber (strain DSM
13855)
Length = 321
Score = 224 bits (548), Expect = 1e-57
Identities = 106/211 (50%), Positives = 138/211 (65%)
Frame = +1
Query: 82 VEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 261
+ F N + P++GLGTWKS PGEV +AV A++ GYRH+DCA +Y NE EVG A++
Sbjct: 4 ISFENGDEMPMIGLGTWKSPPGEVYEAVTTALEAGYRHVDCAPIYKNETEVGAALSDSFD 63
Query: 262 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 441
G + R+D+++TSKLWN H PD VR AL++TL +L + LDLYLIHWP A + + FP
Sbjct: 64 AGGIRRDDVWVTSKLWNNAHHPDDVRPALEQTLSDLRLDALDLYLIHWPVALQPEVD-FP 122
Query: 442 TDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVE 621
+ V +TW AME L K+GLV+ IGVSNF+ L+ +L V+P +NQVE
Sbjct: 123 ESPDDFVSPEAVPLTETWAAMEALKKDGLVRHIGVSNFSVPNLQMILDAGEVRPEMNQVE 182
Query: 622 CHPYLNQKRLKEFCEARGVKITAYSPLGSPD 714
HPYL Q L F EA + ITAYSPLGS D
Sbjct: 183 MHPYLPQPELVSFAEAHNIPITAYSPLGSGD 213
>UniRef50_UPI000065D0BD Cluster: Homolog of Homo sapiens "AKR1B1
protein.; n=1; Takifugu rubripes|Rep: Homolog of Homo
sapiens "AKR1B1 protein. - Takifugu rubripes
Length = 330
Score = 224 bits (547), Expect = 2e-57
Identities = 113/240 (47%), Positives = 151/240 (62%), Gaps = 26/240 (10%)
Frame = +1
Query: 73 VPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 252
+P V N P+LGLGTWKS G T+AVK AI GYRHID AYVY NE EVG + +
Sbjct: 2 IPSVTLNTGALMPVLGLGTWKSGKGVTTEAVKVAIGAGYRHIDTAYVYENETEVGAGVQA 61
Query: 253 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQ------- 411
I +GVV RE+LFI SKLW TFH P LVRGA ++TL +LN+ Y+DLYL+H+P
Sbjct: 62 MIDQGVVKREELFIVSKLWCTFHTPSLVRGACEKTLSSLNLDYVDLYLMHFPMGALSATL 121
Query: 412 -----------AYKEDGSL------FPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSI 540
+++ L FP D+ ++ ++DTW+AME LV +GL K+I
Sbjct: 122 DLTSLTDVIPTVFRDFSPLQPGEDPFPLDEHNQLICDGTSFLDTWEAMEELVDDGLAKAI 181
Query: 541 GVSNFNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPD 714
G+SNFN Q+E +L + KP NQ+ECHP+LNQ++L FC +RG+ +TA++ LGS D
Sbjct: 182 GISNFNKDQIEAVLNKPGLKHKPATNQIECHPHLNQEKLIHFCRSRGISVTAFACLGSAD 241
>UniRef50_UPI0000E4A7CE Cluster: PREDICTED: similar to LOC553452
protein; n=6; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to LOC553452 protein -
Strongylocentrotus purpuratus
Length = 321
Score = 223 bits (545), Expect = 3e-57
Identities = 106/206 (51%), Positives = 141/206 (68%), Gaps = 2/206 (0%)
Frame = +1
Query: 103 KCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRE 282
K P+LG GTW+ KP EV + ++ AID GYRHID A +YGNEK VG+ I +KI +G + RE
Sbjct: 15 KLPLLGFGTWQIKPEEVGRVIETAIDCGYRHIDEASLYGNEKGVGDGIKAKIDDGTIKRE 74
Query: 283 DLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKI 462
DLF+TSKLW T P V + +++L +L + YLDL+LIH P + FP D +G
Sbjct: 75 DLFVTSKLWVTDSHPSRVEPSCRQSLSDLGLAYLDLFLIHCPTSAVGGKGPFPMDDNGLF 134
Query: 463 QFSD-VDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVN-QVECHPYL 636
D +DYVDTW+ ME LV +GLV++IGVSNF Q++R+L P+ N QVECHP+L
Sbjct: 135 IGDDTIDYVDTWRIMESLVDKGLVRAIGVSNFTVAQIQRVLDLPPKYPIANVQVECHPFL 194
Query: 637 NQKRLKEFCEARGVKITAYSPLGSPD 714
Q L EFC+ +G+ +TAYSPLGSP+
Sbjct: 195 AQNELIEFCKKQGITVTAYSPLGSPE 220
>UniRef50_Q8K023 Cluster: Aldo-keto reductase family 1 member C18;
n=72; Tetrapoda|Rep: Aldo-keto reductase family 1 member
C18 - Mus musculus (Mouse)
Length = 323
Score = 223 bits (544), Expect = 5e-57
Identities = 105/219 (47%), Positives = 147/219 (67%), Gaps = 5/219 (2%)
Frame = +1
Query: 67 SSVPFVEFNNELKCPILGLGTWKSKPG---EVTQAVKDAIDIGYRHIDCAYVYGNEKEVG 237
S + +E N+ P+LG GT+ ++ + ++ K AID+G+ HIDC+++Y NE+E+G
Sbjct: 3 SKIQKIELNDGHSIPVLGFGTYATEEHLKKKSMESTKIAIDVGFCHIDCSHLYQNEEEIG 62
Query: 238 EAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAY 417
+AI SKI++G V RED+F TSKLW+T HRP+LVR +L+ +L LN+ Y+DLYLIH+P +
Sbjct: 63 QAILSKIEDGTVKREDIFYTSKLWSTSHRPELVRPSLENSLRKLNLDYVDLYLIHFPVSL 122
Query: 418 KEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATV 597
K L P D+ G + F VD DTW+AME GL KSIGVSNFN +QLE +L +
Sbjct: 123 KPGNELLPKDEHGNLIFDTVDLCDTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGL 182
Query: 598 --KPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGS 708
KPV NQVECH YLNQ +L +C+ + + AY LG+
Sbjct: 183 KYKPVCNQVECHLYLNQSKLLAYCKMNDIVLVAYGALGT 221
>UniRef50_Q7JVH6 Cluster: LD24696p; n=2; Sophophora|Rep: LD24696p -
Drosophila melanogaster (Fruit fly)
Length = 311
Score = 222 bits (543), Expect = 6e-57
Identities = 103/212 (48%), Positives = 143/212 (67%)
Frame = +1
Query: 76 PFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSK 255
P + NN + P LGLGTWKS + + + A+D+GYRH+D A+VY NE EVG+AI+ K
Sbjct: 6 PTIRLNNGREMPTLGLGTWKSFESDAYHSTRHALDVGYRHLDTAFVYENEAEVGQAISEK 65
Query: 256 IKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSL 435
I EGVVTRE++F+T+KL H P LV A + +L NL ++Y+DLYL+H P K
Sbjct: 66 IAEGVVTREEVFVTTKLGGIHHDPALVERACRLSLSNLGLEYVDLYLMHMPVGQKFHND- 124
Query: 436 FPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQ 615
++ G ++ +DVDY+DTW+ ME LV GL +SIG+SNFN+ Q ER+L + ++PVVNQ
Sbjct: 125 --SNVHGTLELTDVDYLDTWREMEKLVDLGLTRSIGLSNFNAAQTERVLANCRIRPVVNQ 182
Query: 616 VECHPYLNQKRLKEFCEARGVKITAYSPLGSP 711
VECHP Q++L+E + G+ I AY PL P
Sbjct: 183 VECHPGFQQRQLREHAKRHGLVICAYCPLARP 214
>UniRef50_Q5BKE9 Cluster: LOC594893 protein; n=5; Xenopus
tropicalis|Rep: LOC594893 protein - Xenopus tropicalis
(Western clawed frog) (Silurana tropicalis)
Length = 345
Score = 221 bits (539), Expect = 2e-56
Identities = 103/198 (52%), Positives = 136/198 (68%), Gaps = 2/198 (1%)
Frame = +1
Query: 124 GTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDLFITSK 303
GT KS +V A K A+D+GYRH+D A++Y +E VG+A K +G + REDLF TSK
Sbjct: 47 GTEKSFIDDVRVATKMALDLGYRHVDGAFLYSSETGVGQAFREKFADGTLKREDLFYTSK 106
Query: 304 LWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDY 483
LWNTFH+P LVR AL++TL L + Y+DLYLIH P ++K LFP ++ G F D
Sbjct: 107 LWNTFHQPHLVRPALEKTLSFLQMDYVDLYLIHMPMSFKPAEELFPKNEDGTCAFDQPDL 166
Query: 484 VDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATV--KPVVNQVECHPYLNQKRLKE 657
+ TW+A+E GLVKSIGVSNFN +QLE +L + KPV NQ+ECHPYLNQK++ E
Sbjct: 167 LQTWQALEECRDAGLVKSIGVSNFNRRQLEMILNKPGLKYKPVCNQIECHPYLNQKQMLE 226
Query: 658 FCEARGVKITAYSPLGSP 711
FC+++ + + AY LGSP
Sbjct: 227 FCKSKDIVVVAYGVLGSP 244
>UniRef50_Q8VC28 Cluster: Aldo-keto reductase family 1 member C13;
n=11; Theria|Rep: Aldo-keto reductase family 1 member
C13 - Mus musculus (Mouse)
Length = 323
Score = 217 bits (530), Expect = 2e-55
Identities = 104/214 (48%), Positives = 147/214 (68%), Gaps = 5/214 (2%)
Frame = +1
Query: 82 VEFNNELKCPILGLGTWKSKPGEVTQAVKDA---IDIGYRHIDCAYVYGNEKEVGEAITS 252
V+ N+ P LG GT+K K +++++ A +D+GYRH+D AY Y E+E+G+AI S
Sbjct: 8 VKLNDGHLIPALGFGTYKPKEVPKSKSLEAACLALDVGYRHVDTAYAYQVEEEIGQAIQS 67
Query: 253 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGS 432
KIK GVV REDLFIT+KLW T RP+LV+ AL+++L L + Y+DLY++H+P K +
Sbjct: 68 KIKAGVVKREDLFITTKLWCTCFRPELVKPALEKSLKKLQLDYVDLYIMHYPVPMKSGDN 127
Query: 433 LFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATV--KPV 606
FP ++ GK VD+ DTW+ +E GLVKSIGVSNFN +QLER+L + KPV
Sbjct: 128 DFPVNEQGKSLLDTVDFCDTWERLEECKDAGLVKSIGVSNFNHRQLERILNKPGLKYKPV 187
Query: 607 VNQVECHPYLNQKRLKEFCEARGVKITAYSPLGS 708
NQVECH YLNQ++L ++CE++ + + AY LG+
Sbjct: 188 CNQVECHLYLNQRKLLDYCESKDIVLVAYGALGT 221
>UniRef50_Q7QVQ9 Cluster: GLP_302_44328_45269; n=1; Giardia lamblia
ATCC 50803|Rep: GLP_302_44328_45269 - Giardia lamblia
ATCC 50803
Length = 313
Score = 213 bits (521), Expect = 3e-54
Identities = 101/203 (49%), Positives = 133/203 (65%), Gaps = 4/203 (1%)
Frame = +1
Query: 109 PILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV--VTRE 282
P LG GTW++ P V AV+ A+ GYRHIDCAYVY NE+ +G A K+ + RE
Sbjct: 5 PRLGFGTWQAPPEAVQTAVETALMTGYRHIDCAYVYQNEEAIGRAFGKIFKDASSGIKRE 64
Query: 283 DLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKED--GSLFPTDQSG 456
D++ITSKLWN HRP+LVR ++T+ +L V YLDL+L+HWP A+ + G LFP D G
Sbjct: 65 DVWITSKLWNYNHRPELVREQCKKTMSDLQVDYLDLFLVHWPLAFVRNDVGDLFPKDAEG 124
Query: 457 KIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYL 636
+ V DTW+AME LV+EGLVK IGVSN+ L LL +A +KP+VNQ+E HP+
Sbjct: 125 RAMLEKVPLADTWRAMEQLVEEGLVKHIGVSNYTVPLLADLLNYAKIKPLVNQIEIHPWH 184
Query: 637 NQKRLKEFCEARGVKITAYSPLG 705
+FC G+ +TAYSP+G
Sbjct: 185 PNDATVKFCLDNGIGVTAYSPMG 207
>UniRef50_P51857 Cluster: 3-oxo-5-beta-steroid 4-dehydrogenase (EC
1.3.1.3) (Delta(4)-3- ketosteroid 5-beta-reductase);
n=124; cellular organisms|Rep: 3-oxo-5-beta-steroid
4-dehydrogenase (EC 1.3.1.3) (Delta(4)-3- ketosteroid
5-beta-reductase) - Homo sapiens (Human)
Length = 326
Score = 213 bits (520), Expect = 4e-54
Identities = 108/206 (52%), Positives = 136/206 (66%), Gaps = 6/206 (2%)
Frame = +1
Query: 109 PILGLGTW---KSKP-GEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVT 276
PI+GLGT+ KS P G +VK AID GYRHID AY+Y NE EVGEAI KI EG V
Sbjct: 19 PIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIREKIAEGKVR 78
Query: 277 REDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSG 456
RED+F KLW T H P++VR L+ TL L + Y+DLY+I P A+K ++P D++G
Sbjct: 79 REDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGDEIYPRDENG 138
Query: 457 KIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATV--KPVVNQVECHP 630
K + + TW+AME GLVKS+GVSNFN +QLE +L + KPV NQVECHP
Sbjct: 139 KWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKPVSNQVECHP 198
Query: 631 YLNQKRLKEFCEARGVKITAYSPLGS 708
Y Q +L +FC+ + ITAYSPLG+
Sbjct: 199 YFTQPKLLKFCQQHDIVITAYSPLGT 224
>UniRef50_Q55FL3 Cluster: Aldo-keto reductase; n=2; Dictyostelium
discoideum AX4|Rep: Aldo-keto reductase - Dictyostelium
discoideum AX4
Length = 321
Score = 212 bits (517), Expect = 8e-54
Identities = 106/213 (49%), Positives = 143/213 (67%), Gaps = 6/213 (2%)
Frame = +1
Query: 85 EFNNELKCPILGLGTWKSK-PGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 261
+ N+ + P +GLGT+ S+ PGEV A+ +A+ GYRHID A YGNEK +G ++ K
Sbjct: 18 KLNDGNQIPSIGLGTYYSENPGEVGDAINNALKNGYRHIDGAAFYGNEKVIGNSLKEIFK 77
Query: 262 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 441
EG + RED+F TSKLWN+ H +LV +T+++L + YLDLYLIHWP A++ L
Sbjct: 78 EGEIKREDIFYTSKLWNSCHNSNLVVKHCVKTIEDLGIGYLDLYLIHWPIAFENSNPLGL 137
Query: 442 T-----DQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPV 606
T DQ+G + V +TW+ ME LV+ GLVKSIGVSNFN + L LL +A +KPV
Sbjct: 138 TIEPLRDQNGNPIIAPVSIRETWQEMEKLVELGLVKSIGVSNFNVQNLVDLLTYAKIKPV 197
Query: 607 VNQVECHPYLNQKRLKEFCEARGVKITAYSPLG 705
VNQVE HPYL Q +L+E+C+ +K+ AYSPLG
Sbjct: 198 VNQVEIHPYLTQFKLQEYCDKYEIKLVAYSPLG 230
>UniRef50_Q2V420 Cluster: Uncharacterized protein At2g37770.1; n=1;
Arabidopsis thaliana|Rep: Uncharacterized protein
At2g37770.1 - Arabidopsis thaliana (Mouse-ear cress)
Length = 283
Score = 209 bits (511), Expect = 5e-53
Identities = 103/207 (49%), Positives = 137/207 (66%)
Frame = +1
Query: 67 SSVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAI 246
+++ F + N K P +GLGTW++ PG V AV A+ IGYRHIDCA +YGNEKE+G +
Sbjct: 3 NAITFFKLNTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGAVL 62
Query: 247 TSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKED 426
++ VV REDLFITSKLW T H P V AL TL +L ++Y+DLYLIHWP K+
Sbjct: 63 KKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKK- 121
Query: 427 GSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPV 606
GS+ ++ VD TWKAME L G ++IGVSNF++K+L LL+ A V P
Sbjct: 122 GSVGIKPEN----LLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVPPA 177
Query: 607 VNQVECHPYLNQKRLKEFCEARGVKIT 687
VNQVECHP Q +L+EFC+++GV ++
Sbjct: 178 VNQVECHPSWRQTKLQEFCKSKGVHLS 204
>UniRef50_UPI0000498F1F Cluster: oxidoreductase, aldo/keto reductase
family; n=2; Entamoeba histolytica HM-1:IMSS|Rep:
oxidoreductase, aldo/keto reductase family - Entamoeba
histolytica HM-1:IMSS
Length = 305
Score = 208 bits (508), Expect = 1e-52
Identities = 106/211 (50%), Positives = 136/211 (64%)
Frame = +1
Query: 79 FVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 258
+ NN K P LGLGTW S GEV +AV+ AI GYRHIDCA YGNEKEVG+ I S I
Sbjct: 4 YFTLNNGYKIPKLGLGTWMSANGEVGKAVEIAIKNGYRHIDCAKAYGNEKEVGDGIKSAI 63
Query: 259 KEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLF 438
+G V RE+LF+T+KLW+T + VR A E+L L ++YLDLY+IH P L
Sbjct: 64 AKGYVKREELFVTTKLWSTDKHKEDVRPACLESLKKLQLEYLDLYIIHIP--------LT 115
Query: 439 PTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQV 618
++G+ + +TW+ ME LV+EGLVKSIGVSNFN K+LE LL A ++P VNQ
Sbjct: 116 ADKKTGEFTEEIIPIEETWREMEKLVEEGLVKSIGVSNFNIKKLEELLAIAKIQPAVNQF 175
Query: 619 ECHPYLNQKRLKEFCEARGVKITAYSPLGSP 711
E H Y + +L +FC+ + IT Y PLG+P
Sbjct: 176 EFHIYYQRPKLHQFCKKHNIHITGYCPLGNP 206
>UniRef50_Q10494 Cluster: Probable oxidoreductase C26F1.07; n=2;
Schizosaccharomyces pombe|Rep: Probable oxidoreductase
C26F1.07 - Schizosaccharomyces pombe (Fission yeast)
Length = 321
Score = 208 bits (508), Expect = 1e-52
Identities = 99/202 (49%), Positives = 133/202 (65%)
Frame = +1
Query: 103 KCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRE 282
K P LGLGTW+S+P + AVK A+ GYRHID A +YGNE EVG+ I KE V R+
Sbjct: 23 KIPGLGLGTWRSEPNQTKNAVKTALQYGYRHIDAAAIYGNEDEVGDGI----KESGVPRK 78
Query: 283 DLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKI 462
D+++TSKLW H P+ V AL++TL +L + YLD YLIHWP ++K FP D+ G +
Sbjct: 79 DIWVTSKLWCNAHAPEAVPKALEKTLKDLKLDYLDEYLIHWPVSFKTGEDKFPKDKDGNL 138
Query: 463 QFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQ 642
+ +TWKAME L++ G V+ IG+SNFN LER+L+ A VKP V+Q+E HP+L Q
Sbjct: 139 IYEKNPIEETWKAMEKLLETGKVRHIGLSNFNDTNLERILKVAKVKPAVHQMELHPFLPQ 198
Query: 643 KRLKEFCEARGVKITAYSPLGS 708
E + G+ +TAYSP G+
Sbjct: 199 TEFVEKHKKLGIHVTAYSPFGN 220
>UniRef50_P27800 Cluster: Aldehyde reductase 1; n=18; root|Rep:
Aldehyde reductase 1 - Sporobolomyces salmonicolor
Length = 323
Score = 208 bits (507), Expect = 1e-52
Identities = 106/211 (50%), Positives = 138/211 (65%), Gaps = 5/211 (2%)
Frame = +1
Query: 91 NNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 270
N ++G GTW++ PGEV Q VK AI+ GYRH+D A VY N+ EVG AI KE
Sbjct: 8 NTGASLELVGYGTWQAAPGEVGQGVKVAIETGYRHLDLAKVYSNQPEVGAAI----KEAG 63
Query: 271 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDG----SLF 438
V REDLFITSKLWN HRP+ V AL +TL L ++YLDLYLIHWP A+ +G +LF
Sbjct: 64 VKREDLFITSKLWNNSHRPEQVEPALDDTLKELGLEYLDLYLIHWPVAFPPEGDITQNLF 123
Query: 439 PTDQSGKIQFS-DVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQ 615
P +++ +V VDTWKAM L+ G VK+IGVSNF++K ++ +++ V P VNQ
Sbjct: 124 PKANDKEVKLDLEVSLVDTWKAMVKLLDTGKVKAIGVSNFDAKMVDAIIEATGVTPSVNQ 183
Query: 616 VECHPYLNQKRLKEFCEARGVKITAYSPLGS 708
+E HP L Q L +A+ + ITAYSPLG+
Sbjct: 184 IERHPLLLQPELIAHHKAKNIHITAYSPLGN 214
>UniRef50_Q0IBY6 Cluster: Alcohol dehydrogenase; n=2;
Chroococcales|Rep: Alcohol dehydrogenase - Synechococcus
sp. (strain CC9311)
Length = 336
Score = 207 bits (505), Expect = 2e-52
Identities = 101/215 (46%), Positives = 139/215 (64%)
Frame = +1
Query: 70 SVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAIT 249
++ + +N + P+LGLGT KS+ +V ++V++AI IGYRHIDCA +YGNE+EVG+AI
Sbjct: 18 TMQYASLSNGDRMPLLGLGTGKSESRQVYKSVREAIKIGYRHIDCASIYGNEEEVGDAIR 77
Query: 250 SKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDG 429
I+ +TR +L+ITSKLW+ H + V AL ++L NL V YL+LYLIHWP + +
Sbjct: 78 DAIQNHEITRSELWITSKLWSNCHGKNHVEAALSQSLQNLGVDYLNLYLIHWPVGIRPE- 136
Query: 430 SLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVV 609
F + + +TW+AME +GL K IGVSNF K+L++L+ H KP V
Sbjct: 137 KTFAESVDDLLTPEESPISETWEAMESTRDKGLTKHIGVSNFTVKKLQQLVSHCKQKPEV 196
Query: 610 NQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPD 714
NQVE HP L Q L E+C + + ITAYSPLGS D
Sbjct: 197 NQVEHHPLLQQPTLIEYCASEEILITAYSPLGSMD 231
>UniRef50_A3U9Y0 Cluster: Aldehyde reductase; n=5;
Bacteroidetes|Rep: Aldehyde reductase - Croceibacter
atlanticus HTCC2559
Length = 316
Score = 207 bits (505), Expect = 2e-52
Identities = 98/211 (46%), Positives = 132/211 (62%)
Frame = +1
Query: 82 VEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 261
++F + P +GLGTWKS P +V +AVK A++ GY+HIDCA Y NE VGEA +
Sbjct: 4 LKFRDGDSIPSIGLGTWKSDPEDVKKAVKIALENGYKHIDCAAAYDNEDAVGEAFKESFE 63
Query: 262 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 441
G V RED+F+TSKLWN H+ + V AL++TL +LN+ YLDLYL+HWP A+K + FP
Sbjct: 64 SGNVKREDIFVTSKLWNNAHKKEDVIPALKKTLKDLNLDYLDLYLMHWPVAFKPSVNGFP 123
Query: 442 TDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVE 621
+ + +T AM K+GL+K +GVSNF+ ++LE L P +NQVE
Sbjct: 124 EKDEDYLSLEEAPLHETLNAMIEAKKQGLIKHVGVSNFSKEKLESLKGKVEEMPEMNQVE 183
Query: 622 CHPYLNQKRLKEFCEARGVKITAYSPLGSPD 714
HPYL Q L +C G+ +T YSPLGS D
Sbjct: 184 LHPYLPQNDLYSYCSKEGILLTGYSPLGSGD 214
>UniRef50_A2R6Z3 Cluster: Catalytic activity: an alcohol + NADP(+)
<=> an aldehyde + NADPH; n=9; Pezizomycotina|Rep:
Catalytic activity: an alcohol + NADP(+) <=> an aldehyde
+ NADPH - Aspergillus niger
Length = 345
Score = 206 bits (503), Expect = 4e-52
Identities = 100/210 (47%), Positives = 137/210 (65%), Gaps = 2/210 (0%)
Frame = +1
Query: 85 EFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKE 264
+ N P +GLGTW+SK EV AV A+ GYRHID A VYGNE+EVG+ + +
Sbjct: 8 KLNTGYDMPAVGLGTWQSKKDEVRDAVIAALKCGYRHIDAAAVYGNEQEVGDGM----RL 63
Query: 265 GVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP- 441
V RE++F+TSKLWNT H P+ V A+ ++L +L YLDLYLIHWP A++ +
Sbjct: 64 SGVPREEIFLTSKLWNTHHHPENVEEAVDKSLADLQTDYLDLYLIHWPVAFRYSTTTIQP 123
Query: 442 -TDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQV 618
+Q+G I DV DTW AME LV++G V+SIGVSNF +++E LL+ A + P VNQ+
Sbjct: 124 VNEQTGLIDVVDVPIKDTWAAMEKLVEKGKVRSIGVSNFTREKIEELLKTAKITPAVNQI 183
Query: 619 ECHPYLNQKRLKEFCEARGVKITAYSPLGS 708
E HP+L Q+ L E+ +G+ + YSPLG+
Sbjct: 184 EAHPFLQQRDLLEWSTQKGIVVAGYSPLGN 213
>UniRef50_Q96UH3 Cluster: Aldehyde reductase; n=13;
Pezizomycotina|Rep: Aldehyde reductase - Coccidioides
posadasii
Length = 314
Score = 204 bits (497), Expect = 2e-51
Identities = 93/200 (46%), Positives = 132/200 (66%)
Frame = +1
Query: 109 PILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 288
P +G GTW+ + + AV A+ GYRHID A VYG EK +G A+ ++R++L
Sbjct: 17 PAIGFGTWQDENAQ-EDAVLTALSAGYRHIDTAAVYGTEKAIGRALA----RSRLSRDEL 71
Query: 289 FITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQF 468
FITSKLWN HRP+ V A+ ++L NL + YLDLYL+HWP A+ +FP D G +
Sbjct: 72 FITSKLWNNKHRPEDVEQAIDQSLKNLEIDYLDLYLMHWPAAFAPGDDMFPKDSQGNSKT 131
Query: 469 SDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKR 648
D+DYVDT+KAME LVK G K+IG+SNF+ ++ERLL+ ++ P V Q+E HP+L Q
Sbjct: 132 VDIDYVDTYKAMEKLVKSGKTKAIGISNFSKGEMERLLESCSIVPAVMQMELHPWLQQND 191
Query: 649 LKEFCEARGVKITAYSPLGS 708
E+ +++G+ +T YS LG+
Sbjct: 192 FVEWLKSKGIHVTQYSSLGN 211
>UniRef50_UPI0000D9A956 Cluster: PREDICTED: similar to aldo-keto
reductase family 1, member B10, partial; n=1; Macaca
mulatta|Rep: PREDICTED: similar to aldo-keto reductase
family 1, member B10, partial - Macaca mulatta
Length = 275
Score = 198 bits (484), Expect = 8e-50
Identities = 109/202 (53%), Positives = 131/202 (64%), Gaps = 8/202 (3%)
Frame = +1
Query: 133 KSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDLFITSK--- 303
KS G+V +AVK AID GYRHIDCAYVY NE EVGEAI KI+E V REDLFI SK
Sbjct: 42 KSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEQAVKREDLFIVSKVHM 101
Query: 304 ---LWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSD 474
LW TF LVR A ++TL +L + YLD+YLIHWPQ +K
Sbjct: 102 AHWLWTTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFK------------------ 143
Query: 475 VDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATV--KPVVNQVECHPYLNQKR 648
AME LV EGLVK++G+SNFN Q+E+LL + KPV NQVECHPYL Q++
Sbjct: 144 --------AMEELVDEGLVKALGISNFNHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEK 195
Query: 649 LKEFCEARGVKITAYSPLGSPD 714
L ++C ++G+ ITAYSPLGSPD
Sbjct: 196 LIQYCHSKGITITAYSPLGSPD 217
>UniRef50_P38715 Cluster: NADPH-dependent aldose reductase GRE3;
n=39; cellular organisms|Rep: NADPH-dependent aldose
reductase GRE3 - Saccharomyces cerevisiae (Baker's
yeast)
Length = 327
Score = 198 bits (484), Expect = 8e-50
Identities = 102/224 (45%), Positives = 140/224 (62%), Gaps = 10/224 (4%)
Frame = +1
Query: 64 MSSVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEA 243
MSS+ V NN LK P++GLG WK + +AI +GYR D A YGNEKEVGE
Sbjct: 1 MSSL--VTLNNGLKMPLVGLGCWKIDKKVCANQIYEAIKLGYRLFDGACDYGNEKEVGEG 58
Query: 244 ITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYK- 420
I I EG+V+R+D+F+ SKLWN FH PD V+ AL++TL ++ + YLDLY IH+P A+K
Sbjct: 59 IRKAISEGLVSRKDIFVVSKLWNNFHHPDHVKLALKKTLSDMGLDYLDLYYIHFPIAFKY 118
Query: 421 -EDGSLFP--------TDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLE 573
+P ++ G I + V +DT++A+E V EGL+KSIGVSNF ++
Sbjct: 119 VPFEEKYPPGFYTGADDEKKGHITEAHVPIIDTYRALEECVDEGLIKSIGVSNFQGSLIQ 178
Query: 574 RLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLG 705
LL+ +KPV Q+E HPYL Q+ L EFC+ +++ AYS G
Sbjct: 179 DLLRGCRIKPVALQIEHHPYLTQEHLVEFCKLHDIQVVAYSSFG 222
>UniRef50_Q7ZWA4 Cluster: Zgc:56622; n=6; cellular organisms|Rep:
Zgc:56622 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 289
Score = 198 bits (483), Expect = 1e-49
Identities = 92/186 (49%), Positives = 129/186 (69%), Gaps = 1/186 (0%)
Frame = +1
Query: 157 QAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLV 336
+A + AI GYRHID A+ Y NE +VG AI +KI++G++ R+D+FI SKLW T H P+ +
Sbjct: 4 RACEAAIAAGYRHIDTAFCYRNEVDVGMAIQNKIQQGIIRRQDMFIVSKLWGTHHAPEDI 63
Query: 337 RGALQETLDNLNVQYLDLYLIHWPQAYKEDGS-LFPTDQSGKIQFSDVDYVDTWKAMEPL 513
++L +L + YLD YL+H+P K+ G LFP ++ GKI +D+DYVD W+ ME L
Sbjct: 64 PVCFNKSLSDLQLDYLDQYLVHFPVGLKKVGDELFP-ERDGKILTTDIDYVDVWRGMEAL 122
Query: 514 VKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAY 693
G VKSIGVSNF +Q++RLL A + P VNQVE HPYL Q L ++C+++ + +TA+
Sbjct: 123 KATGKVKSIGVSNFTMEQIDRLLSVAKIPPAVNQVELHPYLVQSDLIDYCKSKNIALTAH 182
Query: 694 SPLGSP 711
SP GSP
Sbjct: 183 SPFGSP 188
>UniRef50_Q22352 Cluster: Putative uncharacterized protein T08H10.1;
n=2; Caenorhabditis|Rep: Putative uncharacterized
protein T08H10.1 - Caenorhabditis elegans
Length = 333
Score = 197 bits (480), Expect = 3e-49
Identities = 94/216 (43%), Positives = 141/216 (65%), Gaps = 2/216 (0%)
Frame = +1
Query: 70 SVPFVEFNNELKCPILGLGTWKSKP-GEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAI 246
+V + N + P+ GLGTW+ K E+T A++ A+D GYR ID A++Y NE +G+ +
Sbjct: 2 TVDSIPLNTGAQLPLFGLGTWQVKDEAELTVALRAALDAGYRLIDTAHLYQNEHIIGKVL 61
Query: 247 TSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYK-E 423
I G + RED+F+TSKL T H P+ V ++ L L ++Y+DLYLIH P +K +
Sbjct: 62 HEYISSGKLKREDIFVTSKLPFTAHAPEDVPKCVESQLKALQLEYIDLYLIHCPFPFKHQ 121
Query: 424 DGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKP 603
+GS P ++G++ +++ ++DTW+A+E L KEG +K++GVSNF+ QL+ L A VKP
Sbjct: 122 EGSFAPLMENGELAVTEIAHIDTWRALEKLYKEGKLKALGVSNFSCNQLQALYDAAEVKP 181
Query: 604 VVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSP 711
QVECH Y Q+ L+ C+ GV +TAY+PLGSP
Sbjct: 182 ANQQVECHIYWPQQELRALCKKLGVTVTAYAPLGSP 217
>UniRef50_Q7ZA52 Cluster: Aldose reductase; n=6; Pezizomycotina|Rep:
Aldose reductase - Magnaporthe grisea (Rice blast
fungus) (Pyricularia grisea)
Length = 312
Score = 195 bits (476), Expect = 8e-49
Identities = 101/210 (48%), Positives = 129/210 (61%), Gaps = 4/210 (1%)
Frame = +1
Query: 91 NNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 270
N K P GLGTW+ G + +AV AI GYR ID AYVYGNE+EVG+ I I G+
Sbjct: 9 NTGAKIPAFGLGTWQGDKGVIKEAVLTAIKSGYRLIDGAYVYGNEEEVGQGIREAISSGI 68
Query: 271 VTREDLFITSKLWNTFH-RPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGS--LFP 441
V REDLF+ SK W T+ R +L L ++L L + Y+DLYL+HWP +G+ FP
Sbjct: 69 VKREDLFVVSKCWATYTTRCEL---GLDQSLKLLGLDYVDLYLVHWPILMNPEGNDEKFP 125
Query: 442 TDQSGKIQFSDV-DYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQV 618
G ++VDTWK ME L G K++GVSN++ LE+LL HAT P VNQV
Sbjct: 126 KHADGSRDIIHTHNHVDTWKLMEKLPATGKTKAVGVSNYSKAWLEQLLPHATTVPAVNQV 185
Query: 619 ECHPYLNQKRLKEFCEARGVKITAYSPLGS 708
E HP L Q+ L +FC+ +G+ I AYSPLGS
Sbjct: 186 ENHPQLPQQELVDFCKEKGIHIMAYSPLGS 215
>UniRef50_A4RQH8 Cluster: Predicted protein; n=2; Ostreococcus|Rep:
Predicted protein - Ostreococcus lucimarinus CCE9901
Length = 337
Score = 195 bits (475), Expect = 1e-48
Identities = 96/205 (46%), Positives = 127/205 (61%), Gaps = 2/205 (0%)
Frame = +1
Query: 94 NELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVV 273
N L+ P +GLGTWK++P EV AV+DA+ GY H+DCA Y NE EVGEA+ + G
Sbjct: 12 NGLRIPRVGLGTWKARPNEVRDAVRDALGAGYAHVDCAAAYANESEVGEALREAFERGDA 71
Query: 274 TREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQS 453
RED+F+TSKLWN RP VR AL TL++L V YLDLYLIHWP A+K G++ D
Sbjct: 72 KREDVFVTSKLWNDRRRPRDVREALMTTLNDLGVGYLDLYLIHWPVAWKR-GTVLQPDAE 130
Query: 454 GKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQ--HATVKPVVNQVECH 627
I + W +E V +GLV+ IGVSNFN QL L ++P NQ+E H
Sbjct: 131 ASI-------AECWSELERCVADGLVRHIGVSNFNEAQLAALCDDPRTKIQPACNQIESH 183
Query: 628 PYLNQKRLKEFCEARGVKITAYSPL 702
P + L ++ +++G+ +TAYSPL
Sbjct: 184 PLWSNDSLVKYSQSKGLTVTAYSPL 208
>UniRef50_Q9VHX4 Cluster: CG2767-PA; n=4; Endopterygota|Rep:
CG2767-PA - Drosophila melanogaster (Fruit fly)
Length = 329
Score = 195 bits (475), Expect = 1e-48
Identities = 94/218 (43%), Positives = 141/218 (64%), Gaps = 3/218 (1%)
Frame = +1
Query: 64 MSSVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEA 243
M + F+ FNN K P++G+GTW++ E+ A+ A++ GYRHID A VYGNEK +G
Sbjct: 1 MVNTKFLTFNNGEKMPVIGIGTWQASDEEIETAIDAALEAGYRHIDTAPVYGNEKAIGRV 60
Query: 244 ITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA--Y 417
+ + G V RE+LFI +K+ +RP V ++++L++L + Y+DLYL+H P
Sbjct: 61 LKRWLDAGKVKREELFIVTKVPPVSNRPHEVEPTIKKSLEDLQLDYVDLYLVHTPFTINI 120
Query: 418 KEDGSLFPTDQSGKIQFS-DVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHAT 594
EDGS F D+ G ++ ++ W AME LV++GL KSIGVSNF+ Q+ RLL++
Sbjct: 121 NEDGS-FKLDKEGLMEVDVTTNHAAIWVAMEALVEKGLTKSIGVSNFSKDQVARLLKNCK 179
Query: 595 VKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGS 708
++P NQ+E H YL Q+ L +FC++ + +TAYSPLGS
Sbjct: 180 IRPANNQIEHHVYLQQRDLVDFCKSENITVTAYSPLGS 217
>UniRef50_Q8SSK6 Cluster: ALDOSE REDUCTASE; n=1; Encephalitozoon
cuniculi|Rep: ALDOSE REDUCTASE - Encephalitozoon
cuniculi
Length = 301
Score = 193 bits (471), Expect = 3e-48
Identities = 95/211 (45%), Positives = 132/211 (62%), Gaps = 3/211 (1%)
Frame = +1
Query: 85 EFNNELKCPILGLGTWKSKPGEVTQ-AVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 261
+ NN + P +GLGTW + V + A+++A+ +GYRHID A++YGNEK +G +
Sbjct: 7 KLNNGKEIPTVGLGTWGMEDEAVLEGAIRNALSLGYRHIDTAFIYGNEKMIGNILKKLFD 66
Query: 262 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKE--DGSL 435
EGVV R+DLFITSKLWNTFH L+ +L++L + Y+DLYLIHWP + DG++
Sbjct: 67 EGVVQRKDLFITSKLWNTFH--GCPEDGLRRSLNDLQMDYVDLYLIHWPVTFDPAPDGTV 124
Query: 436 FPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQ 615
+ K D V WK ME LV GL KSIG+SNF E++L + P Q
Sbjct: 125 ESCGK--KYNVGKFDAVGVWKKMEALVDLGLAKSIGISNFGKANTEKILGTCRICPAAIQ 182
Query: 616 VECHPYLNQKRLKEFCEARGVKITAYSPLGS 708
+E HPYLNQK L EF +++G+++ +YS LGS
Sbjct: 183 IELHPYLNQKELVEFMKSKGIQVISYSSLGS 213
>UniRef50_Q2UGR1 Cluster: Aldo/keto reductase family proteins; n=2;
Ascomycota|Rep: Aldo/keto reductase family proteins -
Aspergillus oryzae
Length = 323
Score = 193 bits (471), Expect = 3e-48
Identities = 96/210 (45%), Positives = 131/210 (62%), Gaps = 2/210 (0%)
Frame = +1
Query: 85 EFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKE 264
+ N+ P +GLGTW SKP EV AV+ A+ GYRHID A Y NE EVG K+
Sbjct: 8 KLNSGYNIPAIGLGTWLSKPHEVENAVEAALRAGYRHIDAAACYQNENEVGNGW----KK 63
Query: 265 GVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDG-SLFP 441
V R+ +FITSKLWNT H P+ V A+ +TL +L YLDLYLIHWP A++ +L P
Sbjct: 64 SGVPRDQIFITSKLWNTHHHPEHVEEAVNKTLKDLQTDYLDLYLIHWPVAFEHTNETLTP 123
Query: 442 TDQSGK-IQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQV 618
D K + ++V DTW A+E LV+ ++SIG+SNF +++ LL+ A + P VNQ+
Sbjct: 124 IDPVTKRFRLANVPIADTWAALEKLVEAKKIRSIGISNFTQDKIDDLLKTAKIPPAVNQI 183
Query: 619 ECHPYLNQKRLKEFCEARGVKITAYSPLGS 708
E HPYL Q L ++ + + + AYSPLG+
Sbjct: 184 EAHPYLQQPGLHKYLKEKNILSVAYSPLGN 213
>UniRef50_UPI0000E45E29 Cluster: PREDICTED: similar to aldose
reductase; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to aldose reductase -
Strongylocentrotus purpuratus
Length = 274
Score = 192 bits (469), Expect = 6e-48
Identities = 98/195 (50%), Positives = 122/195 (62%)
Frame = +1
Query: 130 WKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDLFITSKLW 309
W SKPG+V AVK AID GYRHIDCA+VYGNE EVG + K VV RED+FITSKLW
Sbjct: 5 WMSKPGQVEAAVKAAIDCGYRHIDCAHVYGNEAEVGAGLKEKFDANVVKREDIFITSKLW 64
Query: 310 NTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVD 489
N H PD V A TL NL + Y+DLYL+HWP AY
Sbjct: 65 NNKHHPDDVEQACDITLKNLQLSYVDLYLMHWPMAY------------------------ 100
Query: 490 TWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEA 669
+AME LV G K+IG+SNF+ K ++R+++ AT++P QVE HP L Q++L EFC+
Sbjct: 101 --QAMEKLVTSGKCKAIGLSNFSMKMMKRVIEKATIQPANLQVELHPLLTQEKLIEFCKE 158
Query: 670 RGVKITAYSPLGSPD 714
+ +TAYSPLG+PD
Sbjct: 159 HNMTVTAYSPLGAPD 173
>UniRef50_Q96JD6-2 Cluster: Isoform 2 of Q96JD6 ; n=4;
Catarrhini|Rep: Isoform 2 of Q96JD6 - Homo sapiens
(Human)
Length = 263
Score = 190 bits (462), Expect = 4e-47
Identities = 99/191 (51%), Positives = 123/191 (64%), Gaps = 21/191 (10%)
Frame = +1
Query: 109 PILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 288
P +GL +WK+ PG+VT+AVK+AID GYRH DCAY Y NE+EVG I KIKEG V REDL
Sbjct: 5 PAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDL 64
Query: 289 FITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKED--------GSL--- 435
FI +KLW T H+ LV A +++L L + YLDLYLIHWP +K L
Sbjct: 65 FIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSFC 124
Query: 436 --------FPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHA 591
P D+S + SD D++DTW+AME LV GLVK+IGVSNFN +QLERLL
Sbjct: 125 LSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKP 184
Query: 592 TV--KPVVNQV 618
+ KP+ NQ+
Sbjct: 185 GLRFKPLTNQI 195
>UniRef50_A7PNI3 Cluster: Chromosome chr1 scaffold_22, whole genome
shotgun sequence; n=2; Vitis vinifera|Rep: Chromosome
chr1 scaffold_22, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 360
Score = 190 bits (462), Expect = 4e-47
Identities = 91/208 (43%), Positives = 135/208 (64%), Gaps = 1/208 (0%)
Frame = +1
Query: 91 NNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 270
N + K P +GLGTW+S +AVK A+ GYR IDCA++YGNE EVGEA+ G
Sbjct: 15 NTKAKIPAIGLGTWQSGGDLCVEAVKRALSEGYRQIDCAHLYGNEVEVGEALAEAFN-GS 73
Query: 271 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQ 450
+ RED+F+TSKL+ T + + + +++ +L NL V YLDLYL+HWP + P
Sbjct: 74 LKREDVFLTSKLYCTMNSLNKIENSVRVSLKNLGVTYLDLYLMHWPDITAFGDATDPPSN 133
Query: 451 SGKIQFSDVDYVD-TWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECH 627
SG ++ + WKAME L++ GLV++IGVSNF +Q++ LL+ A + P VNQV+ H
Sbjct: 134 SGNDHRQFLNRLKKAWKAMEGLIELGLVRAIGVSNFGVQQIKELLKFAKIVPAVNQVKLH 193
Query: 628 PYLNQKRLKEFCEARGVKITAYSPLGSP 711
P+ Q L +FC+++G+ ++A++PLG P
Sbjct: 194 PFWRQDELVKFCQSKGIHVSAHTPLGVP 221
>UniRef50_Q9Y020 Cluster: 3-dehydroecdysone 3beta-reductase
precursor; n=1; Spodoptera littoralis|Rep:
3-dehydroecdysone 3beta-reductase precursor - Spodoptera
littoralis (Egyptian cotton leafworm)
Length = 345
Score = 190 bits (462), Expect = 4e-47
Identities = 96/221 (43%), Positives = 135/221 (61%), Gaps = 9/221 (4%)
Frame = +1
Query: 73 VPFVEFNNELKCPILGLGTW---------KSKPGEVTQAVKDAIDIGYRHIDCAYVYGNE 225
VP ++ N+ + P + LGT+ SK ++ V AID+GYRH D A +Y E
Sbjct: 22 VPMLKMLNDREMPAIALGTYLGFDKGGAVTSKDKQLRNVVMQAIDLGYRHFDTAAIYNTE 81
Query: 226 KEVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHW 405
EVGEAI KI EGV+ RED+F+T+KLWNT H+ + V A++ETL+ + Y+DL+L+HW
Sbjct: 82 AEVGEAIRMKIDEGVIKREDVFLTTKLWNTHHKREQVAVAMKETLNKTGLDYVDLFLMHW 141
Query: 406 PQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQ 585
P A ED S S+ DY++TW+A E +VK G KSIG+SNFN Q+ +LQ
Sbjct: 142 PIALNEDYS-----------HSNTDYLETWRATEEMVKLGYTKSIGLSNFNKLQVATVLQ 190
Query: 586 HATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGS 708
T+KPV Q+E HP + Q+ L + + G+ + YSP GS
Sbjct: 191 ECTIKPVALQIEVHPQIIQEDLITYAKDEGIIVMGYSPFGS 231
>UniRef50_A2EYY6 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=9; Trichomonas vaginalis G3|Rep:
Oxidoreductase, aldo/keto reductase family protein -
Trichomonas vaginalis G3
Length = 308
Score = 189 bits (461), Expect = 5e-47
Identities = 103/214 (48%), Positives = 136/214 (63%), Gaps = 10/214 (4%)
Frame = +1
Query: 103 KCPILGLGTWKSKPGE-----VTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEG 267
+ P +GLGTWKS E +T A+K+A GY HIDCA Y NE VG+A+ G
Sbjct: 3 RIPTIGLGTWKSPRSEDLVNAITYAIKEA---GYVHIDCALCYENEDIVGQALQQCWDSG 59
Query: 268 VVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKE---DGSLF 438
+ RE+++ITSKLWNT HR ++V A ++TL +L + YLDLYL+H+P A++ GSL
Sbjct: 60 I-KRENIWITSKLWNTHHRLEIVEEACRKTLKDLRLDYLDLYLMHYPFAFQNTGIGGSLN 118
Query: 439 PTDQSGKIQFSD-VDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERL-LQHATVKPVVN 612
P D+ G F D V +DTWKAME LV++GLVK IGVSN+ QLERL A P N
Sbjct: 119 PLDEKGNTIFDDGVSLIDTWKAMEKLVEKGLVKRIGVSNWTINQLERLKYSDAKTTPYTN 178
Query: 613 QVECHPYLNQKRLKEFCEARGVKITAYSPLGSPD 714
QVE + Y+ Q L+E+ G+ +T YS LG+PD
Sbjct: 179 QVEFNLYMQQGPLREYMHKEGIIVTGYSTLGTPD 212
>UniRef50_Q1YPE5 Cluster: Aldehyde reductase; n=7; Bacteria|Rep:
Aldehyde reductase - gamma proteobacterium HTCC2207
Length = 330
Score = 189 bits (460), Expect = 7e-47
Identities = 95/221 (42%), Positives = 141/221 (63%), Gaps = 9/221 (4%)
Frame = +1
Query: 73 VPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 252
VP V+ +++ P +GLG WK QAV +AI +GYRH+D A YGNE++VGE I
Sbjct: 7 VPGVKVSSK-SMPAVGLGLWKITQDSAAQAVYEAIKVGYRHLDSAADYGNEQQVGEGIAR 65
Query: 253 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA--YKED 426
I EG+ +RE+L+IT+KLWNT+HR + V A + ++D+L + Y+DLYL+H+P A Y +
Sbjct: 66 AIAEGLCSREELWITTKLWNTYHRAEHVEAACRRSMDDLGLDYIDLYLVHFPIALRYVDF 125
Query: 427 GSLFPT----DQSGKIQFSDVDYV---DTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQ 585
+P D S + ++D V +TW AME LV+ GLV+ IGV N+++ L L+
Sbjct: 126 NDRYPAEWIFDHSAEDPAMELDQVPLSETWGAMEQLVESGLVRQIGVCNYSAVLLHDLMS 185
Query: 586 HATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGS 708
+A +KP + Q+E HPYL Q+ L + + +TA+SPLGS
Sbjct: 186 YARIKPAMLQIESHPYLTQEALLRTARSYNMAVTAFSPLGS 226
>UniRef50_Q16K66 Cluster: Aldo-keto reductase; n=2; Aedes
aegypti|Rep: Aldo-keto reductase - Aedes aegypti
(Yellowfever mosquito)
Length = 303
Score = 188 bits (458), Expect = 1e-46
Identities = 93/209 (44%), Positives = 135/209 (64%), Gaps = 2/209 (0%)
Frame = +1
Query: 91 NNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 270
NN P +GLGT+K + A+K A++ GYR ID A+VY NE+ VG+A+ +G
Sbjct: 5 NNGHSIPPIGLGTYKITGSDGVAAIKSAVEFGYRLIDTAFVYNNEQVVGQALREIFSQGN 64
Query: 271 -VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTD 447
+ RED+FI SKL TFHRP+ V + +L+ L + Y+DLYL+H P A ++ G D
Sbjct: 65 DINREDVFIVSKLGPTFHRPEAVEKGCRLSLERLGLDYVDLYLMHTPVAARDSG-----D 119
Query: 448 QSGKIQFSD-VDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVEC 624
+ + + D V ++TWKA+E ++GLV+SIGVSNFN +QL ++ H +++PVVNQVEC
Sbjct: 120 GNDRSEIDDEVTPLETWKALEECQRKGLVRSIGVSNFNEEQLMEIVTHGSIRPVVNQVEC 179
Query: 625 HPYLNQKRLKEFCEARGVKITAYSPLGSP 711
+Q +L++FC G+ I AYSPLG P
Sbjct: 180 SIGFHQVKLRKFCNREGILIMAYSPLGKP 208
>UniRef50_A2QVE5 Cluster: Similarity: shows similarity to several
dehydrogenases of different specificities; n=4;
Pezizomycotina|Rep: Similarity: shows similarity to
several dehydrogenases of different specificities -
Aspergillus niger
Length = 381
Score = 188 bits (457), Expect = 2e-46
Identities = 94/216 (43%), Positives = 128/216 (59%), Gaps = 7/216 (3%)
Frame = +1
Query: 82 VEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 261
V N+ + P LG GTW+S PG+V AV +A+ GYRH+D A +Y N++EV E I K
Sbjct: 7 VTLNSGAQIPQLGFGTWQSAPGQVGDAVYEALKAGYRHLDLATIYQNQREVAEGIKRAYK 66
Query: 262 EGV-VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLF 438
+ + RED+FITSKLWN+ H P +V AL E L L + YLDLYL+HWP ++ LF
Sbjct: 67 DVPGLKREDIFITSKLWNSQHDPAVVEKALDECLAELELDYLDLYLVHWPVSFTTGSELF 126
Query: 439 PTDQSGKIQFSDV------DYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVK 600
P + ++ DV VDTWKAM L K +++GVSN LE ++ V
Sbjct: 127 PLVKDSSVEGGDVVINDDISIVDTWKAMTQLPK-SKARTVGVSNHMIPHLEAIINATGVV 185
Query: 601 PVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGS 708
P VNQ+E HP L L E+C+ +G+ +TAYS G+
Sbjct: 186 PAVNQIERHPVLQSNELIEYCQKKGIHVTAYSAFGN 221
>UniRef50_Q9U2J5 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 339
Score = 186 bits (453), Expect = 5e-46
Identities = 83/215 (38%), Positives = 135/215 (62%), Gaps = 5/215 (2%)
Frame = +1
Query: 82 VEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 261
V N+ + P++G GTW+ + V+DA++ GYRHID A + N++EV I K
Sbjct: 7 VTLNSGYEMPVIGYGTWQLPKNLAAERVRDALEAGYRHIDSALSFKNQEEVAAGIKDWCK 66
Query: 262 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKED----- 426
V RE+LF++SK+WNT+H + + E L+ Y+DL +IHWP + ED
Sbjct: 67 IRKVRREELFLSSKIWNTYHSRNRCMQQIDEMLEIFETTYMDLIVIHWPFGWAEDEPPGE 126
Query: 427 GSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPV 606
L+P +GK+++SDVDY++TWKA+E + G ++SIG++NFN Q+E++ +KP
Sbjct: 127 RGLWPRGANGKMRYSDVDYLETWKALEDAHRSGKIRSIGLANFNIGQVEQVWTKGLIKPA 186
Query: 607 VNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSP 711
V QVE +P+L+Q+ +++FC +G+ +TA+ G+P
Sbjct: 187 VLQVEMNPFLDQEEIRQFCREKGIILTAFMLTGNP 221
>UniRef50_UPI0000499B0E Cluster: oxidoreductase, aldo/keto reductase
family; n=1; Entamoeba histolytica HM-1:IMSS|Rep:
oxidoreductase, aldo/keto reductase family - Entamoeba
histolytica HM-1:IMSS
Length = 307
Score = 186 bits (452), Expect = 6e-46
Identities = 96/206 (46%), Positives = 132/206 (64%), Gaps = 1/206 (0%)
Frame = +1
Query: 91 NNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGE-AITSKIKEG 267
NN P +GLGTW + PGEV +AV A++ GYR IDCA Y NEKE+GE I +K
Sbjct: 9 NNGKFMPAIGLGTWLAAPGEVGKAVTLALENGYRLIDCARFYKNEKEIGEMGIEPFLKNH 68
Query: 268 VVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTD 447
RE+LF+TSKLW + +R + E++ +L +YLDLYLIHWP A K D S P
Sbjct: 69 --PREELFVTSKLW--MDQVTRIRESCLESIQDLKCKYLDLYLIHWPIALKVDASNPPKP 124
Query: 448 QSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECH 627
+ F D+D + W+ ME LV EGLVKSIG+SNF Q+E++++ +KPV+NQVE +
Sbjct: 125 ED----FLDMDITEIWQEMERLVDEGLVKSIGLSNFTIPQIEKIMKMCRIKPVINQVELN 180
Query: 628 PYLNQKRLKEFCEARGVKITAYSPLG 705
YL Q +L+E C++ + + AY P+G
Sbjct: 181 VYLQQNKLREVCKSYNIVVEAYRPIG 206
>UniRef50_Q1IN88 Cluster: Aldehyde reductase; n=5; Bacteria|Rep:
Aldehyde reductase - Acidobacteria bacterium (strain
Ellin345)
Length = 313
Score = 185 bits (451), Expect = 8e-46
Identities = 87/200 (43%), Positives = 126/200 (63%), Gaps = 1/200 (0%)
Frame = +1
Query: 109 PILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 288
P LG GT + P A +DA+ G+RH DCA Y NE+EVGEA+ + G + RE++
Sbjct: 21 PALGFGTLIADPALTITATRDALAAGFRHFDCAERYRNEREVGEALRAGRAAGNIAREEI 80
Query: 289 FITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQF 468
F+T+KLWNT HRP+ V A + +LD L + YLDLYLIH P A++ P DQ+G + +
Sbjct: 81 FVTTKLWNTNHRPERVEPAFEASLDRLGLDYLDLYLIHTPFAFQPGDEQDPRDQNGSVIY 140
Query: 469 SD-VDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQK 645
+ V +TW A+E LV G ++IG+S+ + +L + + A +KP V QVE HPYL +
Sbjct: 141 DEGVTLRETWSALENLVDRGRCRAIGLSDISMDRLAPIYEAARIKPAVVQVESHPYLPET 200
Query: 646 RLKEFCEARGVKITAYSPLG 705
L EFC+ G+ + A++PLG
Sbjct: 201 ELLEFCKRNGIVLLAFAPLG 220
>UniRef50_Q4PAT5 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 700
Score = 185 bits (451), Expect = 8e-46
Identities = 93/211 (44%), Positives = 135/211 (63%), Gaps = 6/211 (2%)
Frame = +1
Query: 94 NELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVV 273
N + P LG GTWK + T AV AI GYRHIDCA+ Y NE +A+ + IK+ V
Sbjct: 16 NGAQIPKLGFGTWKMSKEQATPAVAHAIKTGYRHIDCAWAYRNE----DAVAAGIKKAGV 71
Query: 274 TREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAY-KEDGSLFPTDQ 450
R L++TSKLWN+FH P+ V AL +L +L YLDLYL+HWP A+ GS+ P+ +
Sbjct: 72 PRSQLWLTSKLWNSFHHPEHVEKALDASLKDLGTDYLDLYLMHWPVAFLNSKGSMVPSIR 131
Query: 451 SG---KIQFSDV--DYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQ 615
S ++ D+ D++ T++ ME +VK+G V++IGVSNFN ++ ++ A++KPVVNQ
Sbjct: 132 STGGHPVESEDLSRDFMATYRVMEEMVKKGKVRNIGVSNFNIRRTSEVVDEASIKPVVNQ 191
Query: 616 VECHPYLNQKRLKEFCEARGVKITAYSPLGS 708
VE + ++ + L+ + A GV + AYSP GS
Sbjct: 192 VEVNLGVHNEELRNYAHAHGVTLQAYSPFGS 222
>UniRef50_Q6TY50 Cluster: Reductase 2; n=10; Magnoliophyta|Rep:
Reductase 2 - Hydrangea macrophylla (Bigleaf hydrangea)
Length = 321
Score = 184 bits (447), Expect = 3e-45
Identities = 93/206 (45%), Positives = 134/206 (65%), Gaps = 4/206 (1%)
Frame = +1
Query: 103 KCPILGLGTWKSKPGE---VTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVV 273
K P+LGLGT P + V +AV +A+ +GYRH D A +Y +E+ +G+AI + EG++
Sbjct: 16 KMPVLGLGTAADPPVDPETVRKAVTEALKLGYRHFDTAALYNSEQPLGDAIAEALGEGLI 75
Query: 274 -TREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQ 450
+R++LFITSKLW + + V ALQ+TL NL ++Y+D+YLIHWP + K +P
Sbjct: 76 KSRDELFITSKLWCSDAHRENVEPALQKTLKNLKLEYIDMYLIHWPVSSKPGNYEYPIK- 134
Query: 451 SGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHP 630
K F +DY W+AME K GL K+IGVSNF+ K+L +L +A V P VNQVE +P
Sbjct: 135 --KEDFLQMDYKSVWEAMEECQKLGLTKAIGVSNFSCKKLSDVLANAKVPPAVNQVEVNP 192
Query: 631 YLNQKRLKEFCEARGVKITAYSPLGS 708
QK+L EFC++ G+ + AY+ LG+
Sbjct: 193 CWQQKQLTEFCKSNGILVVAYAALGA 218
>UniRef50_Q5KI95 Cluster: Aldo-keto reductase, putative; n=14;
Dikarya|Rep: Aldo-keto reductase, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 353
Score = 184 bits (447), Expect = 3e-45
Identities = 96/218 (44%), Positives = 128/218 (58%), Gaps = 3/218 (1%)
Frame = +1
Query: 64 MSSVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEA 243
MS+ + N P +GLGTW++K GEV QAV A+ GYRHID A Y NE EVG
Sbjct: 33 MSAPTSFKLNTGASIPAIGLGTWQAKAGEVRQAVAHALKAGYRHIDGALCYQNEDEVGLG 92
Query: 244 ITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKE 423
I K+ V R ++F+TSK+W+++H D V L TL +L YLDLYLIHWP
Sbjct: 93 I----KDSGVPRSEIFLTSKVWSSYH--DRVEECLDTTLKSLQTDYLDLYLIHWPVRLAP 146
Query: 424 DGS--LFPTDQSGKIQFS-DVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHAT 594
+G+ LFP G D D TW ME ++K+G K+IG+SN +E +++
Sbjct: 147 NGTHPLFPVKPDGSRNLDWDWDQAKTWAQMEDVLKKGKAKAIGLSNAGIPIIEHIIKTGK 206
Query: 595 VKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGS 708
V P VNQVE HPY Q L ++C+ +G+ + AYSPLGS
Sbjct: 207 VTPAVNQVELHPYCPQHALLKYCKEKGILLEAYSPLGS 244
>UniRef50_Q41399 Cluster: Chalcone reductase; n=4;
eudicotyledons|Rep: Chalcone reductase - Sesbania
rostrata
Length = 322
Score = 183 bits (445), Expect = 4e-45
Identities = 93/216 (43%), Positives = 137/216 (63%), Gaps = 4/216 (1%)
Frame = +1
Query: 73 VPFVEFNNELKCPILGLGTW-KSKPGE--VTQAVKDAIDIGYRHIDCAYVYGNEKEVGEA 243
+P V N+ K P++G+GT +S+P + DAI +GYRH D A VYG E+ +G A
Sbjct: 6 IPEVLLNSGHKMPVIGMGTSVESRPSNDVLASIFVDAIQVGYRHFDSASVYGTEEAIGMA 65
Query: 244 ITSKIKEGVV-TREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYK 420
++ I++G++ +R+++FITSK WNT DL+ AL+ TL L ++Y+DLYLIHWP +
Sbjct: 66 VSKAIEQGLIKSRDEVFITSKPWNTDAHHDLIVPALKTTLKKLGMEYVDLYLIHWPVRLR 125
Query: 421 EDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVK 600
D L K D TWKAME + GL KSIG+ N+ +K+L +LL+ AT+
Sbjct: 126 HD--LENPVIFSKEDLLPFDIEGTWKAMEECYRLGLAKSIGICNYGTKKLTKLLEIATIP 183
Query: 601 PVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGS 708
P VNQVE +P Q L+EFC+ +G+ ++A+SPLG+
Sbjct: 184 PAVNQVEMNPSWQQGNLREFCKQKGIHVSAWSPLGA 219
>UniRef50_A2EHN6 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=10; Trichomonas vaginalis|Rep:
Oxidoreductase, aldo/keto reductase family protein -
Trichomonas vaginalis G3
Length = 312
Score = 182 bits (444), Expect = 6e-45
Identities = 89/210 (42%), Positives = 133/210 (63%), Gaps = 6/210 (2%)
Frame = +1
Query: 100 LKCPILGLGTWKSK-PGEVTQAVKDAID-IGYRHIDCAYVYGNEKEVGEAITSKIKEGVV 273
++ P LG GT+ + P ++ A+ AI+ G RHID A+ Y N+ +GE + +G +
Sbjct: 1 MEIPQLGFGTYLANDPAKLKAALHYAIEECGVRHIDTAFAYYNQNVIGETLKEIFAKGKI 60
Query: 274 TREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYK----EDGSLFP 441
RED+FIT+KLW T HR DLV L E L L + Y+DL+LIH P A+K +DG++ P
Sbjct: 61 KREDMFITTKLWCTHHRKDLVEPELHENLAQLQLSYVDLFLIHQPIAFKSLPAKDGTMMP 120
Query: 442 TDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVE 621
D+ GKIQ+ +D ++T+ AME K+GL + IGVSNF+ +QLER+ + +KP NQVE
Sbjct: 121 KDEKGKIQYEQIDILETYHAMEECQKKGLTRHIGVSNFSIEQLERIWFNCEIKPYANQVE 180
Query: 622 CHPYLNQKRLKEFCEARGVKITAYSPLGSP 711
C+ Y K L +CE+ + + A++ +G P
Sbjct: 181 CNIYRQFKPLLSYCESHNIYLMAHTTIGHP 210
>UniRef50_Q17G72 Cluster: Aldo-keto reductase; n=9;
Endopterygota|Rep: Aldo-keto reductase - Aedes aegypti
(Yellowfever mosquito)
Length = 316
Score = 181 bits (441), Expect = 1e-44
Identities = 87/209 (41%), Positives = 129/209 (61%)
Frame = +1
Query: 82 VEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 261
+ F N P LG GTW++ EV +A+ +A++ GYRHID A VY NEK +G+ + +
Sbjct: 7 ITFENGTTMPALGFGTWRASDEEVEKALNEALEAGYRHIDTAPVYLNEKTIGKVLKEWMD 66
Query: 262 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 441
G VTR++LFI +KL R V L+ +LD+L ++Y+DLY +H P E F
Sbjct: 67 AGKVTRDELFIVTKLPPHGTRASTVEKFLKNSLDDLQLEYVDLYHVHVPFTVPEVDGPFL 126
Query: 442 TDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVE 621
+ + + D+V WKAME + + GL ++IG+SNFN +Q++R+L + +KP Q+E
Sbjct: 127 VEDGLIVLETTTDHVALWKAMEEVYEAGLARNIGLSNFNQRQIQRILDNCQIKPANLQIE 186
Query: 622 CHPYLNQKRLKEFCEARGVKITAYSPLGS 708
H YL Q L +FC+A G+ +TAYSPLGS
Sbjct: 187 NHIYLQQPELVKFCKANGITVTAYSPLGS 215
>UniRef50_P26690 Cluster: NAD(P)H-dependent 6'-deoxychalcone
synthase; n=3; Papilionoideae|Rep: NAD(P)H-dependent
6'-deoxychalcone synthase - Glycine max (Soybean)
Length = 315
Score = 180 bits (439), Expect = 2e-44
Identities = 89/217 (41%), Positives = 141/217 (64%), Gaps = 2/217 (0%)
Frame = +1
Query: 58 VKMSSVPFVEFNNELKCPILGLGTWK--SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKE 231
+++ ++ F + + + P++G+G+ + + +A+ +A+ GYRH D A YG+E+
Sbjct: 5 IEIPTIVFPNSSAQQRMPVVGMGSAPDFTCKKDTKEAIIEAVKQGYRHFDTAAAYGSEQA 64
Query: 232 VGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQ 411
+GEA+ I G+V+R+DLF+TSKLW T + P LV AL+++L L ++YLDLYLIHWP
Sbjct: 65 LGEALKEAIHLGLVSRQDLFVTSKLWVTENHPHLVLPALRKSLKTLQLEYLDLYLIHWPL 124
Query: 412 AYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHA 591
+ + FP + + F D W++ME K GL K+IGVSNF+ K+L+ LL A
Sbjct: 125 SSQPGKFSFPIEVEDLLPF---DVKGVWESMEECQKLGLTKAIGVSNFSVKKLQNLLSVA 181
Query: 592 TVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPL 702
T++PVV+QVE + QK+L+EFC+ G+ +TA+SPL
Sbjct: 182 TIRPVVDQVEMNLAWQQKKLREFCKENGIIVTAFSPL 218
>UniRef50_Q01J82 Cluster: OSIGBa0152K17.5 protein; n=28;
Magnoliophyta|Rep: OSIGBa0152K17.5 protein - Oryza
sativa (Rice)
Length = 323
Score = 180 bits (438), Expect = 3e-44
Identities = 91/220 (41%), Positives = 137/220 (62%), Gaps = 6/220 (2%)
Frame = +1
Query: 64 MSSVPFVEFNNEL--KCPILGLGTWKS---KPGEVTQAVKDAIDIGYRHIDCAYVYGNEK 228
M++VP V + P +G+GT S P A A+++G+RH D A +YG E
Sbjct: 1 MAAVPEVALRHGAGRPMPAVGVGTADSAATSPETKRGAALAALEVGFRHFDTAALYGTEA 60
Query: 229 EVGEAITSKIKEGVV-TREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHW 405
+GEAI + G+V +RE++F+T+KLW T P LV +L+E+L NL ++Y+DLYL+HW
Sbjct: 61 PLGEAIAEATRRGLVASREEVFVTTKLWCTQCHPGLVLPSLRESLRNLQMEYVDLYLVHW 120
Query: 406 PQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQ 585
P + K + P + + F D+ W+AME + GL K+IGVSNF +K L++LL
Sbjct: 121 PISVKPGPPMLPVKREDAVPF---DFEGVWRAMEECHRLGLAKAIGVSNFTTKHLDKLLA 177
Query: 586 HATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLG 705
AT+ P VNQVE +P Q+ ++E+C A+G+++ AYSPLG
Sbjct: 178 VATIPPAVNQVEMNPVWQQRTVREYCAAKGIRVAAYSPLG 217
>UniRef50_A2FPE2 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=3; Trichomonas vaginalis G3|Rep:
Oxidoreductase, aldo/keto reductase family protein -
Trichomonas vaginalis G3
Length = 309
Score = 180 bits (438), Expect = 3e-44
Identities = 92/205 (44%), Positives = 134/205 (65%), Gaps = 6/205 (2%)
Frame = +1
Query: 109 PILGLGTWKSK-PGEVTQAVKDAI-DIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRE 282
P +GLGT+ ++ P + AV AI D GYRH+DCA Y N++ +GEA++ +G V RE
Sbjct: 5 PSIGLGTFLAEDPAALKAAVHSAIEDSGYRHVDCAAYYKNQEIIGEALSEIFAKGQVKRE 64
Query: 283 DLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAY--KEDGSLFPTDQSG 456
+++ITSK+WNT HRPDL+ +++TL L ++YLDL L+HW A+ +ED P D++G
Sbjct: 65 EVWITSKVWNTKHRPDLLVKDVKKTLKELKLEYLDLVLVHWACAFQSREDDEYLPRDETG 124
Query: 457 KIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVK--PVVNQVECHP 630
KI ++D ++TWKAME GL K IGVSNF+ +QLER+ VK P NQVE H
Sbjct: 125 KIITENIDILETWKAMEECYNLGLAKHIGVSNFSIEQLERMRYDPGVKIQPYCNQVESHM 184
Query: 631 YLNQKRLKEFCEARGVKITAYSPLG 705
YL Q+ + ++ R + + +Y+ LG
Sbjct: 185 YLQQQPMLDYLTQRKMYMISYTCLG 209
>UniRef50_Q7PLK6 Cluster: CG40064-PA; n=1; Drosophila
melanogaster|Rep: CG40064-PA - Drosophila melanogaster
(Fruit fly)
Length = 361
Score = 180 bits (437), Expect = 4e-44
Identities = 86/178 (48%), Positives = 124/178 (69%), Gaps = 2/178 (1%)
Frame = +1
Query: 148 EVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDLFITSKLWNTFHRP 327
+ + AV AI+ G+RH D AY Y NEKE+GEA+ ++IK G ++RE++F+T+KLWNT H P
Sbjct: 45 QCSAAVHCAIETGFRHFDTAYYYENEKEIGEALRTQIKMGNISRENIFLTTKLWNTHHDP 104
Query: 328 DLVRGALQETLDNLNVQYLDLYLIHWPQAYKE--DGSLFPTDQSGKIQFSDVDYVDTWKA 501
VR ++ L+ L Y+DLYL+H+P YK D L P ++Q ++DY+DTW+A
Sbjct: 105 RDVRRICEKQLELLGFSYIDLYLMHFPVGYKYVCDEILMPM-SGDELQTVEIDYLDTWRA 163
Query: 502 MEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARG 675
ME LVK G+V+SIG+SNFN +Q++R++Q ++ KPVVNQVE P QK L ++C G
Sbjct: 164 MENLVKLGMVRSIGLSNFNMEQIQRIIQCSSSKPVVNQVEIWPGFLQKDLVDYCRYNG 221
>UniRef50_Q6RZX1 Cluster: Gld1; n=22; Pezizomycotina|Rep: Gld1 -
Trichoderma atroviride (Hypocrea atroviridis)
Length = 327
Score = 180 bits (437), Expect = 4e-44
Identities = 94/222 (42%), Positives = 135/222 (60%), Gaps = 7/222 (3%)
Frame = +1
Query: 64 MSSVPFVEFNNELKCPILGLGTWKSK--PGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVG 237
+SS + N K P +G GT+ ++ GE AV A+D+GYRH+DCA+ Y NE EVG
Sbjct: 10 LSSTTYT-LNTGAKIPAVGFGTFANEGAKGETYAAVTKALDVGYRHLDCAWFYLNEDEVG 68
Query: 238 EAITSKI-KEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA 414
+AI + + VTR+DLFI +K+WN H P+ V+ + + + +NL V Y+DL+L+HWP A
Sbjct: 69 DAIRDFLARRPDVTRKDLFICTKVWNHLHEPEDVKWSAKNSCENLKVDYIDLFLVHWPIA 128
Query: 415 YKEDGS-LFPTDQSGKIQFSDV---DYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLL 582
+++ GK + + TW+AME LV G+VK+IGVSN+ L++LL
Sbjct: 129 AEKNADRTVKIGPDGKYVINKALTENPEPTWRAMEELVDSGIVKAIGVSNWTIPGLKQLL 188
Query: 583 QHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGS 708
+ A +KP VNQ+E HP+L L EFC + AYSPLGS
Sbjct: 189 EFARIKPAVNQIEIHPFLPNTELVEFCFQNDILPEAYSPLGS 230
>UniRef50_P23901 Cluster: Aldose reductase; n=9; Poaceae|Rep: Aldose
reductase - Hordeum vulgare (Barley)
Length = 320
Score = 178 bits (433), Expect = 1e-43
Identities = 91/203 (44%), Positives = 129/203 (63%), Gaps = 1/203 (0%)
Frame = +1
Query: 109 PILGLGTWKSKPGEVTQAVKDAI-DIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 285
P +GLGTW++ + +V+ AI + GYRH+D A YG EKEVG+ + + ++ G+ R+D
Sbjct: 25 PAVGLGTWRAG-SDTAHSVRTAITEAGYRHVDTAAEYGVEKEVGKGLKAAMEAGI-DRKD 82
Query: 286 LFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQ 465
LF+TSK+W T P+ VR AL+ TL +L + Y+DLY IHWP K DG+ P + ++
Sbjct: 83 LFVTSKIWCTNLAPERVRPALENTLKDLQLDYIDLYHIHWPFRLK-DGAHMPPEAGEVLE 141
Query: 466 FSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQK 645
F D WK ME LVK+GLVK IGV N+ +L RLL+ A + P V Q+E HP
Sbjct: 142 F---DMEGVWKEMENLVKDGLVKDIGVCNYTVTKLNRLLRSAKIPPAVCQMEMHPGWKND 198
Query: 646 RLKEFCEARGVKITAYSPLGSPD 714
++ E C+ G+ +TAYSPLGS +
Sbjct: 199 KIFEACKKHGIHVTAYSPLGSSE 221
>UniRef50_Q6CFG7 Cluster: Yarrowia lipolytica chromosome B of strain
CLIB122 of Yarrowia lipolytica; n=9; Ascomycota|Rep:
Yarrowia lipolytica chromosome B of strain CLIB122 of
Yarrowia lipolytica - Yarrowia lipolytica (Candida
lipolytica)
Length = 337
Score = 177 bits (432), Expect = 2e-43
Identities = 98/219 (44%), Positives = 131/219 (59%), Gaps = 4/219 (1%)
Frame = +1
Query: 64 MSSVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAI-DIGYRHIDCAYVYGNEKEVGE 240
M+S+ F NN P +GLGTWKS EV AV+ A+ + GYRHID A+ Y NE VG
Sbjct: 29 MTSLDFT-LNNGKTIPAIGLGTWKSTTEEVAGAVECALTEGGYRHIDTAFNYRNEDAVGL 87
Query: 241 AITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYK 420
I +++GV RED+F+T+K+W T+H D V L +L+ L + Y+D+ LIHWP
Sbjct: 88 GIKRAMEKGV-KREDIFVTTKIWVTYH--DRVEENLDMSLERLGLDYVDMLLIHWPVPLN 144
Query: 421 EDGS--LFPTDQSGKIQFSDV-DYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHA 591
+G+ ++P G + TWK ME ++K G KSIGVSNF+ LE LL+ A
Sbjct: 145 PNGNDPVYPLRPDGSRDIDESGSQPKTWKQMEAVLKTGKTKSIGVSNFSIPYLEELLKEA 204
Query: 592 TVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGS 708
V P VNQVE HP L Q L EFC+ + +TA+SP GS
Sbjct: 205 EVVPAVNQVELHPLLPQLELMEFCKKNNIVMTAFSPFGS 243
>UniRef50_UPI00015B4B22 Cluster: PREDICTED: similar to GA15457-PA;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
GA15457-PA - Nasonia vitripennis
Length = 388
Score = 177 bits (431), Expect = 2e-43
Identities = 92/201 (45%), Positives = 126/201 (62%), Gaps = 1/201 (0%)
Frame = +1
Query: 109 PILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 288
P +GLGT K E+ A+ A++ GYRHID A+ Y NE +G+ + +G RED+
Sbjct: 35 PAVGLGTSTIKLDEMDNAISSALENGYRHIDTAFSYDNEAAIGKILKKWFDKGG-KREDI 93
Query: 289 FITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPT-DQSGKIQ 465
FITSKL + +RP V L+ +L +L + Y+D+YLIH P A KE +L D+ G
Sbjct: 94 FITSKLPSQGNRPQSVETYLKRSLKDLGLDYVDMYLIHTPFAVKEGENLSSKQDKDGNDL 153
Query: 466 FSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQK 645
F DVD+ WKAME VKEG KSIG+SNFN Q+ + +A +KP QVE H YL QK
Sbjct: 154 FDDVDHKALWKAMERQVKEGRAKSIGLSNFNQSQVLNIYNNAEIKPSNLQVETHAYLQQK 213
Query: 646 RLKEFCEARGVKITAYSPLGS 708
+L++FC+ + +TAY+PLGS
Sbjct: 214 QLRKFCKEHNIVMTAYAPLGS 234
>UniRef50_A5E082 Cluster: GCY protein; n=4; Saccharomycetales|Rep:
GCY protein - Lodderomyces elongisporus (Yeast)
(Saccharomyces elongisporus)
Length = 295
Score = 177 bits (430), Expect = 3e-43
Identities = 93/212 (43%), Positives = 133/212 (62%), Gaps = 4/212 (1%)
Frame = +1
Query: 91 NNELKCPILGLGTWKSKPGEVT-QAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEG 267
NN LK P +GLGTW + + +A A+ GY+HID A YGNE +VG AI +
Sbjct: 15 NNGLKIPAIGLGTWLADEEDAAYKATLTALKNGYKHIDTAAAYGNEDQVGRAIA----DS 70
Query: 268 VVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTD 447
V+R+++F+T+KLWN H+ GAL E+L L ++Y+DLYLIHWP + D
Sbjct: 71 GVSRDEIFVTTKLWNDQHKDP--EGALDESLKKLGLEYVDLYLIHWPLS---------VD 119
Query: 448 QSGKIQFSDVDYVDTWKAMEPLVKEGL-VKSIGVSNFNSKQLERLL--QHATVKPVVNQV 618
+ + D D+VDTW+ ++ + KEG VK+IGVSNFN K+L++LL + V PV+NQ+
Sbjct: 120 PKTEKPYDDYDFVDTWRNLQKIYKEGKKVKAIGVSNFNKKKLDKLLNSEGVNVVPVINQI 179
Query: 619 ECHPYLNQKRLKEFCEARGVKITAYSPLGSPD 714
E HP L Q L ++ +++ + ITAYSPLG D
Sbjct: 180 EAHPLLTQPDLFDYLKSKDIYITAYSPLGHAD 211
>UniRef50_Q03TW0 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=1; Lactobacillus brevis ATCC
367|Rep: Aldo/keto reductase of diketogulonate reductase
family - Lactobacillus brevis (strain ATCC 367 / JCM
1170)
Length = 293
Score = 176 bits (428), Expect = 5e-43
Identities = 96/214 (44%), Positives = 128/214 (59%), Gaps = 1/214 (0%)
Frame = +1
Query: 67 SSVPFVEFNNELKCPILGLGTWKSKPGEVTQ-AVKDAIDIGYRHIDCAYVYGNEKEVGEA 243
+ +P + NN + P LGLG ++ E T+ A+K A+ GYRHID A YGNE+ VGEA
Sbjct: 9 NDIPDLPMNNGHQIPQLGLGVFQVDNAEDTKNAIKWALAAGYRHIDTAAYYGNEQWVGEA 68
Query: 244 ITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKE 423
I +E V R+ +F+TSKLWN+ D + A QETLD L + YLDLYLIHWP
Sbjct: 69 I----RESDVPRDQIFVTSKLWNSVRGYDETQAAFQETLDKLGLDYLDLYLIHWPAP--- 121
Query: 424 DGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKP 603
Y+D+W+AME L K G +K+IGVSNFN Q+ +L H TVKP
Sbjct: 122 ------------------GYLDSWRAMEDLYKAGKIKNIGVSNFNQTQMADILAHGTVKP 163
Query: 604 VVNQVECHPYLNQKRLKEFCEARGVKITAYSPLG 705
VV+Q+E HPY Q + + E++G+ A+SPLG
Sbjct: 164 VVDQIETHPYFQQNDMHAYLESQGILHEAWSPLG 197
>UniRef50_Q0CLQ2 Cluster: Putative uncharacterized protein; n=1;
Aspergillus terreus NIH2624|Rep: Putative
uncharacterized protein - Aspergillus terreus (strain
NIH 2624)
Length = 301
Score = 176 bits (428), Expect = 5e-43
Identities = 100/224 (44%), Positives = 132/224 (58%), Gaps = 24/224 (10%)
Frame = +1
Query: 109 PILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 288
P +GLGTW SKP EV AV+ A+ +GYRHID A Y NE EVG K+ V R+ +
Sbjct: 16 PAVGLGTWLSKPHEVENAVETALRLGYRHIDAAACYLNENEVGNG----WKKSGVPRDQI 71
Query: 289 FITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYL--------------------IHWP 408
FITSKLWNT H PD V A+ +TL +L YLDLYL IHWP
Sbjct: 72 FITSKLWNTHHHPDHVEEAVNKTLKDLQTDYLDLYLVFPSLLVLIHDLLSLLTNNKIHWP 131
Query: 409 QAYKE-DGSLFPTDQ-SGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLL 582
A++ + +L P D S + + +++ DTW A+E LV G V+SIGVSNF +++E LL
Sbjct: 132 VAFEHTNETLTPIDPVSKRFRLANIPIADTWAALEKLVDAGKVRSIGVSNFTIEKIEELL 191
Query: 583 QHATVKPVVNQVECHPYLNQKRLKEFCEARGVKI--TAYSPLGS 708
+ A + P VNQ+E HPYL Q L ++ + + I AYSPLG+
Sbjct: 192 KTARIPPAVNQIEAHPYLQQPALHKYLKEKVTNILSVAYSPLGN 235
>UniRef50_A1D4E3 Cluster: D-xylose reductase (Xyl1), putative; n=5;
Pezizomycotina|Rep: D-xylose reductase (Xyl1), putative
- Neosartorya fischeri (strain ATCC 1020 / DSM 3700 /
NRRL 181)(Aspergillus fischerianus (strain ATCC 1020 /
DSM 3700 / NRRL 181))
Length = 321
Score = 176 bits (428), Expect = 5e-43
Identities = 86/217 (39%), Positives = 128/217 (58%), Gaps = 5/217 (2%)
Frame = +1
Query: 70 SVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAIT 249
+ P + N+ P++G G WK + AI GYR D A YGNE E G+ +
Sbjct: 2 TTPSTKLNSGYDMPLVGFGLWKVNNETCADQIYHAIKAGYRLFDGACDYGNEVEAGKGVA 61
Query: 250 SKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA--YKE 423
I+EG+V REDLFI SKLWN+FH D V ++ L + + Y DL+++H+P A Y +
Sbjct: 62 RAIQEGIVKREDLFIVSKLWNSFHDGDRVEPICRKQLADWGLDYFDLFIVHFPIALKYVD 121
Query: 424 DGSLFP---TDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHAT 594
+P ++ K++FS+ +TW AME LV + L +SIGVSNF+++ L LL++A
Sbjct: 122 PAVRYPPGWLSENNKLEFSNASIQETWTAMESLVDKKLARSIGVSNFSAQLLMDLLRYAR 181
Query: 595 VKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLG 705
++P Q+E HPYL Q+RL + + G+ +TAYS G
Sbjct: 182 IRPATLQIEHHPYLTQERLVTYAQKEGIAVTAYSSFG 218
>UniRef50_P38115 Cluster: D-arabinose dehydrogenase [NAD(P)+] heavy
chain; n=3; Saccharomycetaceae|Rep: D-arabinose
dehydrogenase [NAD(P)+] heavy chain - Saccharomyces
cerevisiae (Baker's yeast)
Length = 344
Score = 176 bits (428), Expect = 5e-43
Identities = 99/224 (44%), Positives = 137/224 (61%), Gaps = 14/224 (6%)
Frame = +1
Query: 79 FVEFNNELKCPILGLGTWK--SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 252
+ NN ++ P LGLGT K E QAVK AI GYRHID A+ Y E VGEAI
Sbjct: 24 YFSLNNGVRIPALGLGTANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKE 83
Query: 253 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKE--- 423
+++G + REDLFIT+K+W D V +L E+L L ++Y+DL L HWP +++
Sbjct: 84 LLEDGSIKREDLFITTKVWPVLW--DEVDRSLNESLKALGLEYVDLLLQHWPLCFEKIKD 141
Query: 424 ----DGSL-FPTDQSGKIQFS-DVDYVDTWKAMEPLV---KEGLVKSIGVSNFNSKQLER 576
G + P D SGK ++ D DY++T+K +E + + V++IGVSNF+ + LER
Sbjct: 142 PKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYLER 201
Query: 577 LLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGS 708
L++ VKP VNQVE HP+L Q L++FC + +TAYSPLGS
Sbjct: 202 LIKECRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGS 245
>UniRef50_Q1U9L6 Cluster: 2,5-didehydrogluconate reductase; n=3;
Lactobacillus|Rep: 2,5-didehydrogluconate reductase -
Lactobacillus reuteri 100-23
Length = 288
Score = 175 bits (427), Expect = 7e-43
Identities = 91/205 (44%), Positives = 126/205 (61%)
Frame = +1
Query: 91 NNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 270
NN +K P +G GT+++ QAVK+AI+ GYRHID A VYGNE+ VG+ I K+
Sbjct: 14 NNGVKIPCVGYGTFRTPADVAEQAVKEAIETGYRHIDTAAVYGNEEAVGKGI----KDSG 69
Query: 271 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQ 450
+ REDLF+TSKLWNT + + A QETLD L + YLDLYLIHWP K+ G D
Sbjct: 70 IKREDLFVTSKLWNTNRGYEQTKKAFQETLDRLQMDYLDLYLIHWPANEKQFG-----DD 124
Query: 451 SGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHP 630
+ KI +TW+AME L EG +++IGVSNF + L++ A V P V+Q+E HP
Sbjct: 125 AAKIN------AETWRAMEDLYNEGKIRAIGVSNFMPHHIAELMKTAKVAPAVDQIEVHP 178
Query: 631 YLNQKRLKEFCEARGVKITAYSPLG 705
+ ++ +A + + A++PLG
Sbjct: 179 GWPHTEVVKYLQAHNILVEAWAPLG 203
>UniRef50_Q9FJK0 Cluster: Aldose reductase-like protein; n=3; core
eudicotyledons|Rep: Aldose reductase-like protein -
Arabidopsis thaliana (Mouse-ear cress)
Length = 316
Score = 175 bits (426), Expect = 9e-43
Identities = 90/203 (44%), Positives = 127/203 (62%), Gaps = 2/203 (0%)
Frame = +1
Query: 109 PILGLGTW-KSKPGEVT-QAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRE 282
P+LG+GT+ K E T AV AI IGYRH D A +YG+E+ +G A+ I G V R+
Sbjct: 15 PLLGMGTYCPQKDRESTISAVHQAIKIGYRHFDTAKIYGSEEALGTALGQAISYGTVQRD 74
Query: 283 DLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKI 462
DLF+TSKLW++ H + AL +TL + + YLD YL+HWP K G P + +
Sbjct: 75 DLFVTSKLWSSDHHDPI--SALIQTLKTMGLDYLDNYLVHWPIKLKP-GVSEPIPKEDEF 131
Query: 463 QFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQ 642
+ D+ +TW+ ME ++ GL +SIGVSNF+SK++ LL A+V P VNQVE HP Q
Sbjct: 132 E-KDLGIEETWQGMERCLEMGLCRSIGVSNFSSKKIFDLLDFASVSPSVNQVEMHPLWRQ 190
Query: 643 KRLKEFCEARGVKITAYSPLGSP 711
++L++ CE + ++ YSPLG P
Sbjct: 191 RKLRKVCEENNIHVSGYSPLGGP 213
>UniRef50_A6ESC0 Cluster: ARA1; n=1; unidentified eubacterium
SCB49|Rep: ARA1 - unidentified eubacterium SCB49
Length = 280
Score = 174 bits (424), Expect = 2e-42
Identities = 91/213 (42%), Positives = 127/213 (59%), Gaps = 1/213 (0%)
Frame = +1
Query: 79 FVEFNNELKCPILGLGTWKSKPGEVT-QAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSK 255
+ + NN + P +G GTW++ G+ A+K AID GY+HID A +Y NEK VG I
Sbjct: 4 YFKLNNNINIPAIGFGTWQTPDGQTAINAIKTAIDAGYKHIDAAAIYKNEKGVGLGI--- 60
Query: 256 IKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSL 435
KE + R+DLF+TSK+WN + A T+++L + YLDLYLIHWP A +
Sbjct: 61 -KEANIDRKDLFVTSKVWNEQRGYENTLKAFDNTINDLQLDYLDLYLIHWPAAAHQ---- 115
Query: 436 FPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQ 615
++ K Q ++ DTW AME L K+G +K++GVSNF L LLQHAT+KP VNQ
Sbjct: 116 ---FENWK-QLNN----DTWSAMEKLYKDGKIKALGVSNFMEHHLTPLLQHATIKPTVNQ 167
Query: 616 VECHPYLNQKRLKEFCEARGVKITAYSPLGSPD 714
+E HP Q+ +FC +++ +SPLG D
Sbjct: 168 IEYHPGYMQQDCVQFCNDNNIQVEGWSPLGRGD 200
>UniRef50_Q8WRT0 Cluster: 3-dehydrecdysone 3b-reductase; n=1;
Trichoplusia ni|Rep: 3-dehydrecdysone 3b-reductase -
Trichoplusia ni (Cabbage looper)
Length = 308
Score = 174 bits (424), Expect = 2e-42
Identities = 95/211 (45%), Positives = 128/211 (60%), Gaps = 1/211 (0%)
Frame = +1
Query: 76 PFVEFNNELKCPILGLGTWK-SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 252
P + N+ P L LGT+ +V QAV AI GYRHID A +YGNE+EVG+ I
Sbjct: 25 PLKQLNDGNAIPSLALGTFGFGDIPKVRQAVLWAIQAGYRHIDTAALYGNEEEVGKGIAD 84
Query: 253 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGS 432
I++G+V RE+LF+T+KLWN H V AL+E+L L + Y+DLYLIH P+A E+G
Sbjct: 85 AIQQGLVKREELFVTTKLWNDKHGRHQVVPALRESLTKLGLSYVDLYLIHSPEATNENGD 144
Query: 433 LFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVN 612
P D+D ++TW ME K GL KSIGVSNF++ L+RL+ + P VN
Sbjct: 145 --PV---------DIDVLNTWNGMEEAKKLGLAKSIGVSNFDTALLDRLIAGSNTVPAVN 193
Query: 613 QVECHPYLNQKRLKEFCEARGVKITAYSPLG 705
Q+E HP Q++L RG+++ AYSP G
Sbjct: 194 QIEVHPSKTQEKLVADSHERGIEVMAYSPFG 224
>UniRef50_P22045 Cluster: Probable reductase; n=101; cellular
organisms|Rep: Probable reductase - Leishmania major
Length = 284
Score = 174 bits (423), Expect = 2e-42
Identities = 97/209 (46%), Positives = 129/209 (61%), Gaps = 1/209 (0%)
Frame = +1
Query: 82 VEFNNELKCPILGLGTWKSKPGEVTQ-AVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 258
V +N +K P GLG W+S GEVT+ AV A+ GYRHID A +Y NE+ VG +
Sbjct: 9 VTLSNGVKMPQFGLGVWQSPAGEVTENAVNWALCAGYRHIDTAAIYKNEESVGAGL---- 64
Query: 259 KEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLF 438
+ V RED+FIT+KLWNT + A +E+ L V Y+DLYLIHWP+ K+ S
Sbjct: 65 RASGVPREDVFITTKLWNTEQGYESTLAAFEESRQKLGVDYIDLYLIHWPRG-KDILS-- 121
Query: 439 PTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQV 618
+ GK Y+D+W+A E L KE V++IGVSNF+ LE +L TV P+VNQV
Sbjct: 122 ---KEGK------KYLDSWRAFEQLYKEKKVRAIGVSNFHIHHLEDVLAMCTVTPMVNQV 172
Query: 619 ECHPYLNQKRLKEFCEARGVKITAYSPLG 705
E HP NQ L+ FC+A+ +K+ A+SPLG
Sbjct: 173 ELHPLNNQADLRAFCDAKQIKVEAWSPLG 201
>UniRef50_UPI000023D0F1 Cluster: hypothetical protein FG03517.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG03517.1 - Gibberella zeae PH-1
Length = 364
Score = 173 bits (421), Expect = 4e-42
Identities = 90/211 (42%), Positives = 134/211 (63%), Gaps = 3/211 (1%)
Frame = +1
Query: 85 EFN-NEL--KCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSK 255
EFN NE P GLGTW + G V AV+ A+ GYRHID A ++ NE EVG+ I
Sbjct: 50 EFNKNETVRDIPAFGLGTWLAGKGVVVPAVEYALKGGYRHIDTALIWRNEDEVGKGI--- 106
Query: 256 IKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSL 435
K V+R+++++T KLWNT HRP+LVR A++ ++ NL V+YLDLYLIH+P A+
Sbjct: 107 -KASGVSRDEIWVTGKLWNTDHRPELVRKAIETSIANLGVEYLDLYLIHYPVAW------ 159
Query: 436 FPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQ 615
++ + ++ +DTWKAME LV+ GL ++IG SNF K + ++L+ A+++P ++
Sbjct: 160 --VPETRDVD-NNTSLIDTWKAMEELVRAGLTRNIGFSNFAPKDINKILKIASIQPYAHE 216
Query: 616 VECHPYLNQKRLKEFCEARGVKITAYSPLGS 708
E HPYL Q+ +F + +K+ A SPL +
Sbjct: 217 FETHPYLQQQSFVDFHKKENIKVIAASPLAN 247
>UniRef50_P14065 Cluster: Protein GCY; n=13; Saccharomycetales|Rep:
Protein GCY - Saccharomyces cerevisiae (Baker's yeast)
Length = 312
Score = 173 bits (421), Expect = 4e-42
Identities = 95/226 (42%), Positives = 136/226 (60%), Gaps = 11/226 (4%)
Frame = +1
Query: 70 SVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAIT 249
S + N + P +GLGTW+SK + +AV A+ GYRHID A +Y NE +VG+A
Sbjct: 8 STKILSLNTGAQIPQIGLGTWQSKENDAYKAVLTALKDGYRHIDTAAIYRNEDQVGQA-- 65
Query: 250 SKIKEGVVTREDLFITSKLWNT-FHRPDLVRGALQETLDNLNVQYLDLYLIHWP----QA 414
IK+ V RE++F+T+KLW T H P++ AL ++L L + Y+DLYL+HWP A
Sbjct: 66 --IKDSGVPREEIFVTTKLWCTQHHEPEV---ALDQSLKRLGLDYVDLYLMHWPARLDPA 120
Query: 415 Y--KEDGSLFPTDQSGK--IQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLL 582
Y ED PT + G + ++ +++ TW+ M+ L K G K++GVSNF+ L+ LL
Sbjct: 121 YIKNEDILSVPTKKDGSRAVDITNWNFIKTWELMQELPKTGKTKAVGVSNFSINNLKDLL 180
Query: 583 --QHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPD 714
Q + P NQVE HP L Q L FC+++G+ + AYSPLGS D
Sbjct: 181 ASQGNKLTPAANQVEIHPLLPQDELINFCKSKGIVVEAYSPLGSTD 226
>UniRef50_Q8J0K1 Cluster: 4-dihydromethyltrisporate dehydrogenase;
n=2; Parasitella parasitica|Rep:
4-dihydromethyltrisporate dehydrogenase - Parasitella
parasitica
Length = 321
Score = 171 bits (415), Expect = 2e-41
Identities = 88/209 (42%), Positives = 122/209 (58%), Gaps = 6/209 (2%)
Frame = +1
Query: 97 ELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVT 276
E K P+ G G WK + + + AI IGYR D A YGNE EVG I IKEG+V
Sbjct: 12 EDKMPLRGFGCWKIEKKDAENTIYQAIKIGYRLFDGACDYGNEVEVGRGINKAIKEGLVK 71
Query: 277 REDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHW--PQAYKEDGSLFPTD- 447
RE+LFI +KLWNTFH VR A L + ++Y DLYLIH+ P Y + +P +
Sbjct: 72 REELFIVTKLWNTFHSKQHVRTAFDRQLKDWGLEYFDLYLIHFPIPLQYVDPAVSYPPEW 131
Query: 448 ---QSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQV 618
+ K+ F + W ME LV+ L ++IGV+NFN + + LL +A +KP V Q+
Sbjct: 132 YVPHADKLNFERSPIHECWAEMEKLVQAKLTRNIGVANFNCQAILDLLSYAKIKPAVLQI 191
Query: 619 ECHPYLNQKRLKEFCEARGVKITAYSPLG 705
E HP L Q+RL ++ + +G+++TAYS G
Sbjct: 192 EIHPLLPQERLVKWVQEQGIQVTAYSSFG 220
>UniRef50_Q05KR9 Cluster: Benzil reductase; n=5; Bacillales|Rep:
Benzil reductase - Bacillus subtilis
Length = 276
Score = 170 bits (413), Expect = 3e-41
Identities = 94/208 (45%), Positives = 131/208 (62%), Gaps = 1/208 (0%)
Frame = +1
Query: 82 VEFNNELKCPILGLGTWKSKPG-EVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 258
V+ +N ++ P GLG +K + G E T++VK AI GYR ID A +Y NE+ VG I
Sbjct: 9 VKLHNGVEMPWFGLGVFKVENGNEATESVKAAIKNGYRSIDTAAIYKNEEGVGIGI---- 64
Query: 259 KEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLF 438
KE V RE+LFITSK+WN + A +++L+ L + YLDLYLIHWP
Sbjct: 65 KESGVAREELFITSKVWNEDQGYETTLAAFEKSLERLQLDYLDLYLIHWP---------- 114
Query: 439 PTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQV 618
GK + Y DTW+A+E L K+G +++IGVSNF LE LL+ A +KP+VNQV
Sbjct: 115 -----GKDK-----YKDTWRALEKLYKDGKIRAIGVSNFQVHHLEELLKDAEIKPMVNQV 164
Query: 619 ECHPYLNQKRLKEFCEARGVKITAYSPL 702
E HP L QK L+++C+A+G+++ A+SPL
Sbjct: 165 EFHPRLTQKELRDYCKAQGIQLEAWSPL 192
>UniRef50_UPI0000519CC2 Cluster: PREDICTED: similar to CG2767-PA;
n=1; Apis mellifera|Rep: PREDICTED: similar to CG2767-PA
- Apis mellifera
Length = 321
Score = 169 bits (411), Expect = 6e-41
Identities = 86/208 (41%), Positives = 131/208 (62%), Gaps = 2/208 (0%)
Frame = +1
Query: 91 NNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 270
N EL PI+G GTW+++ E+ A+ A++ GYRHID A Y NEK +G+ + +
Sbjct: 10 NGELM-PIIGFGTWQAQEKELEDALNIALEAGYRHIDTATSYENEKVIGDVLKNWFDSKK 68
Query: 271 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGS-LFPTD 447
+ R D+FI +KL +R + V ++ +L NL ++YLDLYLIH P +++ G L P D
Sbjct: 69 LKRSDIFIVTKLPAVGNRAEDVEKWIKTSLQNLRLEYLDLYLIHVPIGFEKVGDILHPFD 128
Query: 448 QSGKIQF-SDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVEC 624
++G I+ + ++V+ W ME VK G K+IG+SNFN Q++R+L++ +K + Q+E
Sbjct: 129 ENGHIRLDNSTNHVEIWAEMEKQVKCGRTKAIGLSNFNISQIKRILKNTKMKISMLQIEL 188
Query: 625 HPYLNQKRLKEFCEARGVKITAYSPLGS 708
H Y QK L +FC+ + ITAYSPLGS
Sbjct: 189 HVYFQQKELVKFCKQENIPITAYSPLGS 216
>UniRef50_Q7PM68 Cluster: ENSANGP00000014386; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000014386 - Anopheles gambiae
str. PEST
Length = 310
Score = 169 bits (410), Expect = 8e-41
Identities = 82/205 (40%), Positives = 120/205 (58%), Gaps = 1/205 (0%)
Frame = +1
Query: 94 NELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKE-GV 270
+ + P +GLGT+ + +A++ AID+GYR D A YGNE VGEAI KI+E
Sbjct: 13 HSIALPTIGLGTYSILGADGKEAIRTAIDVGYRMFDTAVAYGNEAIVGEAIREKIRECNN 72
Query: 271 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQ 450
+TR+D FI SKL ++HR DLV + TLD L + Y+DLYL+H P A + +
Sbjct: 73 LTRDDFFIISKLSGSYHRQDLVEKCCRMTLDRLGMDYVDLYLMHTPVALQSEKKCARNGT 132
Query: 451 SGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHP 630
+ + W +E +EGL +SIGVSNFN Q+ LL A++ P VNQ+EC
Sbjct: 133 KLNAIDDSIAPTEAWIGLEQCYQEGLCRSIGVSNFNEHQINALLSDASIVPAVNQIECSI 192
Query: 631 YLNQKRLKEFCEARGVKITAYSPLG 705
NQ+ +++FC+ + + + Y+PLG
Sbjct: 193 GFNQRPMRKFCQQQNILVMGYTPLG 217
>UniRef50_Q6C2L0 Cluster: Yarrowia lipolytica chromosome F of strain
CLIB122 of Yarrowia lipolytica; n=3; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome F of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 324
Score = 168 bits (409), Expect = 1e-40
Identities = 92/221 (41%), Positives = 133/221 (60%), Gaps = 6/221 (2%)
Frame = +1
Query: 64 MSSVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEA 243
MS + N+ P LGLGT + G V + V AI GYRHID A++YG+E +VG+
Sbjct: 1 MSITDSFKLNDGHSIPALGLGT--ASDGNVEEVVYAAIKNGYRHIDTAFIYGSEVDVGKG 58
Query: 244 ITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKE 423
I I E +V RE+LF+T+K+W TF+ + V +L +L +L++ Y+DL L+HWP +
Sbjct: 59 IKRAIDEELVKRENLFVTTKVWPTFY--NRVSESLDISLKDLSLDYVDLLLVHWPVSLLA 116
Query: 424 DG----SLFPTDQSGKIQFSDV--DYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQ 585
D +++ + G +++SD D++ T+K +E G KSIGVSN + L+RLL
Sbjct: 117 DSDDPRAIYLVNTDGSVRYSDSLDDWITTYKQIEEEKLSGRTKSIGVSNVSEVYLKRLLD 176
Query: 586 HATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGS 708
P VNQ E HPYL QK+ EF E G+ +TA+SPLGS
Sbjct: 177 QVKTVPAVNQFEIHPYLPQKKEIEFNEKHGILVTAFSPLGS 217
>UniRef50_P28475 Cluster: NADP-dependent D-sorbitol-6-phosphate
dehydrogenase; n=71; Magnoliophyta|Rep: NADP-dependent
D-sorbitol-6-phosphate dehydrogenase - Malus domestica
(Apple) (Malus sylvestris)
Length = 310
Score = 168 bits (409), Expect = 1e-40
Identities = 84/212 (39%), Positives = 125/212 (58%), Gaps = 4/212 (1%)
Frame = +1
Query: 82 VEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 261
V ++ + P++GLG W+ + E+ + + +AI IGYRH DCA Y +E +VGEA+ K
Sbjct: 4 VTLSSGYEMPVIGLGLWRLEKDELKEVILNAIKIGYRHFDCAAHYKSEADVGEALAEAFK 63
Query: 262 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 441
G+V RE+LFIT+K+WN+ H V A + +L+ L + YLDLYL+H+P K +
Sbjct: 64 TGLVKREELFITTKIWNSDH--GHVVEACKNSLEKLQIDYLDLYLVHYPMPTKHNAIGKT 121
Query: 442 TDQSGKIQFSDVDYV----DTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVV 609
G+ + D+D TW+ ME V GLV+SIG+SN+ L ++ +KP V
Sbjct: 122 ASLLGEDKVLDIDVTISLQQTWEGMEKTVSLGLVRSIGLSNYELFLTRDCLAYSKIKPAV 181
Query: 610 NQVECHPYLNQKRLKEFCEARGVKITAYSPLG 705
+Q E HPY + L +FC GV TA++PLG
Sbjct: 182 SQFETHPYFQRDSLVKFCMKHGVLPTAHTPLG 213
>UniRef50_Q8F1G4 Cluster: Aldehyde reductase; n=8; Bacteria|Rep:
Aldehyde reductase - Leptospira interrogans
Length = 278
Score = 167 bits (406), Expect = 2e-40
Identities = 88/208 (42%), Positives = 126/208 (60%), Gaps = 1/208 (0%)
Frame = +1
Query: 82 VEFNNELKCPILGLGTWKSKPG-EVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 258
+ NN + PILGLG WK+K G E +AV +A++ GYRHID A +Y NE +VG+AI
Sbjct: 12 IMLNNGISMPILGLGVWKTKSGKECKEAVLNALEAGYRHIDTARIYDNEVDVGQAI---- 67
Query: 259 KEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLF 438
+E + R+++FIT+KLWN D R AL+ +LD L + ++DLYLIH+P K
Sbjct: 68 RESGIPRKEIFITTKLWNADQGSDKTRKALENSLDRLGIDFVDLYLIHFPVTSKR----- 122
Query: 439 PTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQV 618
+D+WK +E L + L K+IGVSN+ L LL+++ + P VNQV
Sbjct: 123 ---------------MDSWKELEKLYHDKLCKAIGVSNYTIIHLTELLKNSQITPAVNQV 167
Query: 619 ECHPYLNQKRLKEFCEARGVKITAYSPL 702
E HP+LNQ L E+C+ +++ AYSPL
Sbjct: 168 EFHPFLNQIHLLEYCKKHKIQLEAYSPL 195
>UniRef50_Q41E86 Cluster: 2,5-didehydrogluconate reductase; n=2;
Bacteria|Rep: 2,5-didehydrogluconate reductase -
Exiguobacterium sibiricum 255-15
Length = 274
Score = 167 bits (406), Expect = 2e-40
Identities = 87/208 (41%), Positives = 124/208 (59%)
Frame = +1
Query: 79 FVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 258
FV NN L P LG G +K EV +AV++A+ +GYR ID A +Y NE VG A+
Sbjct: 3 FVTLNNGLVMPQLGYGVFKVPEQEVYEAVREALRVGYRSIDTAMIYENEAGVGRAL---- 58
Query: 259 KEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLF 438
K+ + RED+F+T+K+WN + A + +L L V Y+DLYLIHWP D L
Sbjct: 59 KDSGIPREDIFLTTKVWNKDQGYERTLAAFETSLQKLGVDYVDLYLIHWPM---PDEDL- 114
Query: 439 PTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQV 618
Y+DTW+A+E L ++G K+IGVSNF+ L R+L+ TV P VNQ+
Sbjct: 115 --------------YMDTWRALEQLYRDGKAKAIGVSNFHIPHLTRVLEEGTVVPAVNQI 160
Query: 619 ECHPYLNQKRLKEFCEARGVKITAYSPL 702
E HP+L+Q+ ++ FC+ G+ + A+SPL
Sbjct: 161 ELHPFLSQEAIRAFCQKNGIVVEAWSPL 188
>UniRef50_A6W8E7 Cluster: 2,5-didehydrogluconate reductase; n=3;
Actinomycetales|Rep: 2,5-didehydrogluconate reductase -
Kineococcus radiotolerans SRS30216
Length = 289
Score = 167 bits (406), Expect = 2e-40
Identities = 88/216 (40%), Positives = 126/216 (58%)
Frame = +1
Query: 55 TVKMSSVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEV 234
+V +VP + N+ + P LG G ++ +PG+ QAVK A+D+GYRHID A +YGNE EV
Sbjct: 6 SVSAMTVPTILLNDGREIPQLGFGVFQIEPGDTAQAVKTALDLGYRHIDTAQMYGNEAEV 65
Query: 235 GEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA 414
+ I + V R+++++TSKL N FH PD R A+ ++++ L +DLYLIHWP
Sbjct: 66 AQGIA----DSGVPRDEIWVTSKLNNGFHEPDAARKAVDDSVEKLRGP-IDLYLIHWP-- 118
Query: 415 YKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHAT 594
PT G D+V TWK +E G ++SIGVSNF L+RL Q AT
Sbjct: 119 -------LPTLYGG-------DFVSTWKVLEEARAAGKLRSIGVSNFQVNHLQRLAQEAT 164
Query: 595 VKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPL 702
V P VNQ+E HPY + ++ C + + A+SP+
Sbjct: 165 VVPAVNQIEVHPYFGNEEVRRHCGEHQIGVEAWSPI 200
>UniRef50_UPI00015B40FA Cluster: PREDICTED: similar to CG2767-PA;
n=2; Nasonia vitripennis|Rep: PREDICTED: similar to
CG2767-PA - Nasonia vitripennis
Length = 356
Score = 167 bits (405), Expect = 3e-40
Identities = 84/204 (41%), Positives = 126/204 (61%), Gaps = 3/204 (1%)
Frame = +1
Query: 109 PILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 288
P++GLGTW+ P + AV A++ GYRHID A+ YGNE+ +G+ + +G REDL
Sbjct: 37 PMIGLGTWQMPPEAIEVAVTAALESGYRHIDTAFTYGNEEAIGKTLKKWFDKGG-KREDL 95
Query: 289 FITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPT--DQSGKI 462
FIT+KL R + V L+ +L+ L ++Y+++YLIH P A+ +D + + G +
Sbjct: 96 FITTKLPPIGMRAEYVESYLKLSLEKLGLEYVNMYLIHKPFAFVKDKYKYEPALNPDGSV 155
Query: 463 QF-SDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLN 639
+D D+V W+AME VK G V+SIG+SNFN QL + +HA +KP Q+E Y
Sbjct: 156 VLDTDTDHVAIWRAMEKQVKAGRVRSIGLSNFNKSQLLNVYEHAEIKPSNLQIELQAYNQ 215
Query: 640 QKRLKEFCEARGVKITAYSPLGSP 711
Q+ ++E C R + +TA+S LGSP
Sbjct: 216 QRPMRELCAERNITVTAFSTLGSP 239
>UniRef50_Q23320 Cluster: Putative uncharacterized protein; n=4;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 320
Score = 167 bits (405), Expect = 3e-40
Identities = 87/215 (40%), Positives = 124/215 (57%)
Frame = +1
Query: 67 SSVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAI 246
S VP +N + P +GLGTW+ E +++A+ GYRHID A +Y NE ++G+A+
Sbjct: 3 SKVPIFTLSNGVLMPSIGLGTWQMTGEEGKTVIRNAVLAGYRHIDTATLYQNEHQIGDAL 62
Query: 247 TSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKED 426
EG++ RED+FIT+K + PD+V AL+ +L L + Y+DLYL H P + K+D
Sbjct: 63 AELFAEGILKREDIFITTKAFCHEVAPDVVEEALRNSLKRLRLDYVDLYLAHIPASTKDD 122
Query: 427 GSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPV 606
GS SDV D W+ E + GL K+IGVSNFN Q+ R++ V
Sbjct: 123 GSF----------RSDVKVEDIWRGFEKVYGLGLTKAIGVSNFNESQIVRIMNIQKVPIH 172
Query: 607 VNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSP 711
+Q+E H YL QK +E C+ + ITAY+ LGSP
Sbjct: 173 ASQLELHLYLPQKAHRELCKKHNILITAYATLGSP 207
>UniRef50_Q9HGY0 Cluster: Glycerol dehydrogenase; n=8;
Saccharomycetaceae|Rep: Glycerol dehydrogenase -
Zygosaccharomyces rouxii (Candida mogii)
Length = 310
Score = 167 bits (405), Expect = 3e-40
Identities = 94/223 (42%), Positives = 135/223 (60%), Gaps = 10/223 (4%)
Frame = +1
Query: 67 SSVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAI 246
+S ++ N P +GLGTW+SK E +AV +A+ GYRHID A VYGNE EVG+A
Sbjct: 6 NSTSTLKLNTGQTIPQVGLGTWRSKENEGYKAVIEALKAGYRHIDGAAVYGNEGEVGKA- 64
Query: 247 TSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYK-- 420
I++ V R ++F+T+KLW T R + AL ++L L + Y+ LYL+HWP +
Sbjct: 65 ---IQDSGVPRNEIFLTTKLWCTHQRNP--QEALDQSLQRLGLDYVGLYLVHWPVPLRTE 119
Query: 421 --EDGSLF----PTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLL 582
+DG+LF D S + + +++ TW+ M+ L++ G K+IGVSNF+ L+ LL
Sbjct: 120 NIKDGNLFQFAEKPDGSKDVDL-EWNFIKTWELMQKLLESGKTKAIGVSNFSVNNLKDLL 178
Query: 583 QHATVK--PVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLG 705
T K P VNQVE HP L Q+ L ++C +G+ I AYSPLG
Sbjct: 179 AAPTTKVTPAVNQVEFHPLLPQEELIQYCSEKGIVIEAYSPLG 221
>UniRef50_Q68ST9 Cluster: Reductase AKOR2; n=2; Pleurotus
djamor|Rep: Reductase AKOR2 - Pleurotus djamor
Length = 306
Score = 166 bits (403), Expect = 6e-40
Identities = 92/221 (41%), Positives = 132/221 (59%), Gaps = 7/221 (3%)
Frame = +1
Query: 64 MSSVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKD----AIDIGYRHIDCAYVYGNEKE 231
MS+ P + N + P L LG W E K+ A+ GYRHID A +Y EK
Sbjct: 1 MSAYPPIVLNTGARMPALALGGWAGLTEEERTQAKEWFLTALKSGYRHIDTAQIYYTEKS 60
Query: 232 VGEAITSKIKEGVVTREDLFITSKL-WNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 408
VG AI +E + RE+LFIT+KL WN R V + Q++L+NL +Y+DLYL+H+P
Sbjct: 61 VGNAI----RESGIPREELFITTKLPWNHHSR---VAESFQKSLENLGTEYIDLYLVHFP 113
Query: 409 Q-AYKEDGSLFPTDQSGKIQFSDVDYV-DTWKAMEPLVKEGLVKSIGVSNFNSKQLERLL 582
Q + ++ + FP + G I+ + + D W +E L+ G VK+IGVSN++ K LE LL
Sbjct: 114 QRVFYDETTDFPRNPDGSIKVVNSPTLNDVWADVETLLDTGKVKAIGVSNYSIKTLEELL 173
Query: 583 QHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLG 705
+ A V P VNQVE HP+L Q +L +C+ +G+ +TAY+P G
Sbjct: 174 KTAKVVPAVNQVELHPFLAQSKLLAYCKEKGIAVTAYTPTG 214
>UniRef50_Q7R2T6 Cluster: GLP_291_56367_57278; n=1; Giardia lamblia
ATCC 50803|Rep: GLP_291_56367_57278 - Giardia lamblia
ATCC 50803
Length = 303
Score = 165 bits (402), Expect = 7e-40
Identities = 84/203 (41%), Positives = 113/203 (55%), Gaps = 4/203 (1%)
Frame = +1
Query: 109 PILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV--VTRE 282
P +G GT+ + E A++ A+ +GYRH DCAY YGNE+ +GE + V RE
Sbjct: 6 PCVGFGTYLVEDPE---AIRSAVKLGYRHFDCAYRYGNERMIGEVFKEIFNDDSYGVKRE 62
Query: 283 DLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKE--DGSLFPTDQSG 456
DL+I SKLW FH P+ V + ETL +L ++YLD++L+HWP A K D +D G
Sbjct: 63 DLWIVSKLWPNFHEPEKVAYQISETLRDLQLEYLDVFLMHWPLAIKHLADRDYASSDGKG 122
Query: 457 KIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYL 636
TW+AME V + + IGVSN + L LL + +KP NQ E PY
Sbjct: 123 GTLLGTTPIRKTWEAMEACVDKKQTRFIGVSNMGTAMLVDLLSYCRIKPFTNQFESQPYF 182
Query: 637 NQKRLKEFCEARGVKITAYSPLG 705
RL EFC + G+ +TAY PLG
Sbjct: 183 PNDRLIEFCNSNGIYVTAYRPLG 205
>UniRef50_A6RKL9 Cluster: Putative uncharacterized protein; n=3;
Sclerotiniaceae|Rep: Putative uncharacterized protein -
Botryotinia fuckeliana B05.10
Length = 360
Score = 165 bits (402), Expect = 7e-40
Identities = 90/203 (44%), Positives = 125/203 (61%), Gaps = 3/203 (1%)
Frame = +1
Query: 109 PILGLGTWKSK--PGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRE 282
P++G GTW K P T+AV AI+IGYR IDCA VYGNE VG I +K + RE
Sbjct: 40 PLIGFGTWNLKVSPENTTEAVAYAIEIGYRQIDCAAVYGNEVAVGRGIEEGLKRAGLKRE 99
Query: 283 DLFITSKLWNTFHRP-DLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGK 459
D+++TSKLWN H + V L +TL +L ++YLDLYLIHWP + +G+
Sbjct: 100 DIWVTSKLWNDHHGSYENVEKGLNQTLQDLGLEYLDLYLIHWPIGFSSNGA--------- 150
Query: 460 IQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLN 639
++D+V T+K+M L K V +IGVSNF+ QL+ ++ T+ P ++Q+E HPYL
Sbjct: 151 ---KNLDHVQTYKSMISLPK-SRVLNIGVSNFSPLQLKNVVSTGTI-PYMHQMELHPYLQ 205
Query: 640 QKRLKEFCEARGVKITAYSPLGS 708
Q +A G+K+TAYSPLG+
Sbjct: 206 QSAWVATHKALGIKMTAYSPLGN 228
>UniRef50_UPI0000D56CE5 Cluster: PREDICTED: similar to CG6084-PA,
isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG6084-PA, isoform A - Tribolium castaneum
Length = 493
Score = 165 bits (401), Expect = 1e-39
Identities = 72/121 (59%), Positives = 95/121 (78%), Gaps = 1/121 (0%)
Frame = +1
Query: 352 ETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTD-QSGKIQFSDVDYVDTWKAMEPLVKEGL 528
E+L NL + YLD+YL+HWP A KE SL P D ++G SDVD+VDTWKAME + ++ L
Sbjct: 271 ESLKNLQLDYLDVYLMHWPHALKEGPSLHPIDPKTGLFIPSDVDFVDTWKAMEKMHEKDL 330
Query: 529 VKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGS 708
KSIG+SNFNS Q++RLL+ A + PV+NQ+ECHPYLNQ +L++FC RG+ +T+YSPLGS
Sbjct: 331 TKSIGISNFNSNQIDRLLKSAKIAPVINQIECHPYLNQSKLRKFCSDRGITVTSYSPLGS 390
Query: 709 P 711
P
Sbjct: 391 P 391
Score = 163 bits (396), Expect = 4e-39
Identities = 88/216 (40%), Positives = 133/216 (61%)
Frame = +1
Query: 61 KMSSVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGE 240
KM +P + NN ++ P+ GL + EV + V+ + YR +DC+ ++ NEK G
Sbjct: 4 KMRDIPIAKLNNGIEIPVFGLAAPQDF-FEV-ENVQLVVSSNYRLMDCS-IFENEKRFGV 60
Query: 241 AITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYK 420
A+ I+ G + R+DLF+ SK T + +LV+ AL +TL L V YLDLYLI P A K
Sbjct: 61 ALQQLIEGGKIRRKDLFLMSKFCCT-NTTNLVKAALLDTLKKLQVAYLDLYLIERPPACK 119
Query: 421 EDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVK 600
D + ++TW+AME L E L ++IG+SNFNSKQ+ER+L++ T++
Sbjct: 120 -----------------DHNLIETWEAMEGLYSEKLTRAIGLSNFNSKQIERILENCTIR 162
Query: 601 PVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGS 708
P VNQ++CHPYLNQ +L+++C G+ + +YSPLG+
Sbjct: 163 PQVNQIQCHPYLNQAKLRKYCSNNGIAVISYSPLGA 198
>UniRef50_Q03PG5 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=1; Lactobacillus brevis ATCC
367|Rep: Aldo/keto reductase of diketogulonate reductase
family - Lactobacillus brevis (strain ATCC 367 / JCM
1170)
Length = 268
Score = 165 bits (400), Expect = 1e-39
Identities = 87/207 (42%), Positives = 123/207 (59%)
Frame = +1
Query: 85 EFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKE 264
+ +N + P+LG GT+ +V A+K A+D GYRH+DCA++YGNE VGEA IK
Sbjct: 5 QLSNGVTIPMLGFGTYLIDSKDVPAAIKTALDAGYRHLDCAHIYGNEPAVGEA----IKA 60
Query: 265 GVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPT 444
+ R DLFITSK+WN D A +TL +L + YLDLYLIHWP ++D L
Sbjct: 61 SGIDRSDLFITSKVWNADQGYDKTLAAFDQTLSDLQLDYLDLYLIHWPN--EDDFEL--- 115
Query: 445 DQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVEC 624
+DTW+ +E L ++ V++IGVSNF+ QL+++ + ATVKP++NQ+E
Sbjct: 116 ------------TLDTWRVLETLYQQKKVRAIGVSNFSEDQLKQVFEMATVKPMINQIER 163
Query: 625 HPYLNQKRLKEFCEARGVKITAYSPLG 705
HPY Q L +F + YSP+G
Sbjct: 164 HPYKVQADLGQFDTDNDIVNEGYSPIG 190
>UniRef50_A2QL02 Cluster: Putative frameshift; n=1; Aspergillus
niger|Rep: Putative frameshift - Aspergillus niger
Length = 357
Score = 165 bits (400), Expect = 1e-39
Identities = 84/207 (40%), Positives = 126/207 (60%), Gaps = 1/207 (0%)
Frame = +1
Query: 91 NNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 270
N K P LG+GT++ P + V + G R ID A VYG E++VG I K+
Sbjct: 41 NTGAKIPALGVGTFQD-PDSQEETVCQVLQRGMRLIDTARVYGVEQQVGRGI----KKSG 95
Query: 271 VTREDLFITSKLW-NTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTD 447
V RE++F+ +KLW N FH PD V A+ ++L +L Y+DL L+H+P +K FP D
Sbjct: 96 VPREEIFLGTKLWCNDFH-PDDVERAVDDSLRDLYTPYVDLLLMHYPCTFKRGEDRFPRD 154
Query: 448 QSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECH 627
G++ + +VDTW+A+E +VK G V++IGVSNF+ ++E LL+ + P V+Q+E H
Sbjct: 155 AEGRMIHGETTFVDTWRALEKVVKTGKVRAIGVSNFSKGEIETLLRETSTVPAVHQMEVH 214
Query: 628 PYLNQKRLKEFCEARGVKITAYSPLGS 708
PYL QK E+ +G+ + +SPLG+
Sbjct: 215 PYLQQKGFNEWLREKGIHVVQFSPLGN 241
>UniRef50_Q5HR31 Cluster: Oxidoreductase, aldo/keto reductase
family; n=3; Staphylococcus|Rep: Oxidoreductase,
aldo/keto reductase family - Staphylococcus epidermidis
(strain ATCC 35984 / RP62A)
Length = 279
Score = 164 bits (398), Expect = 2e-39
Identities = 83/204 (40%), Positives = 121/204 (59%)
Frame = +1
Query: 91 NNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 270
NN P +GLG +K ++ + V+ A+D GYR D AY YGNEK +G A+ K
Sbjct: 9 NNGYPMPAVGLGVYKIADEQMEEVVRTALDAGYRAFDTAYFYGNEKALGSAL----KHSN 64
Query: 271 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQ 450
V R++LFITSKLWN + D ++LDNL + YLDL+LIHWP
Sbjct: 65 VERDELFITSKLWNDYQGYDQTIEYFNKSLDNLGLDYLDLFLIHWPCE------------ 112
Query: 451 SGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHP 630
+D Y++++KA+E L +EG +K+IGV NF LE+L++ + P VNQ+E HP
Sbjct: 113 ------NDQLYIESYKALEHLYEEGKIKAIGVCNFKIHHLEKLMKETKITPQVNQIELHP 166
Query: 631 YLNQKRLKEFCEARGVKITAYSPL 702
Y NQ+ +++FC+ +K+TA+ PL
Sbjct: 167 YFNQQDVQDFCDEHDIKVTAWMPL 190
>UniRef50_A3C1Z7 Cluster: Putative uncharacterized protein; n=2;
Oryza sativa (japonica cultivar-group)|Rep: Putative
uncharacterized protein - Oryza sativa subsp. japonica
(Rice)
Length = 288
Score = 164 bits (398), Expect = 2e-39
Identities = 86/207 (41%), Positives = 123/207 (59%), Gaps = 8/207 (3%)
Frame = +1
Query: 109 PILGLGTWK-----SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVV 273
P +G+GT + P V V AI+ GYRH D A VY E +G+A+ ++ G+V
Sbjct: 13 PRVGMGTASFPLGATDPSTVKDVVLRAIEAGYRHFDTAAVYQTEAILGDAVAEAVRAGLV 72
Query: 274 -TREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYK--EDGSLFPT 444
+R++L+ITSKLW P V +L+ L + ++YLDLYLIH+P + + ED
Sbjct: 73 ASRDELYITSKLWVAHAHPGHVLPSLRRALRKMQMEYLDLYLIHFPVSMRLAEDPESMTY 132
Query: 445 DQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVEC 624
+ + +D WK ME + GL K+IGVSNF+ K+LE LL AT+ P NQVE
Sbjct: 133 SKDDLVM---MDMEGVWKEMEECQRLGLTKAIGVSNFSCKKLETLLSFATISPAANQVEV 189
Query: 625 HPYLNQKRLKEFCEARGVKITAYSPLG 705
HPY Q +L+EFC+ +G+++ AYSPLG
Sbjct: 190 HPYCRQNKLREFCKEKGIQLCAYSPLG 216
>UniRef50_Q4Q5N9 Cluster: Prostaglandin f synthase, putative; n=7;
cellular organisms|Rep: Prostaglandin f synthase,
putative - Leishmania major
Length = 279
Score = 163 bits (395), Expect = 5e-39
Identities = 83/208 (39%), Positives = 122/208 (58%)
Frame = +1
Query: 82 VEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 261
V +N ++ P LG+GTW++K G +K A++ GYRH+D A+ Y NEK VG+ I+
Sbjct: 8 VTLSNGVQVPQLGIGTWEAKDGNEVVNIKWAVNAGYRHVDTAHYYKNEKGVGQGIS---- 63
Query: 262 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 441
E V R D+F+T+KLWN H + A +++ L V+Y+DLYLIHWP +
Sbjct: 64 ECGVPRSDIFVTTKLWNYDHGYESALAAFEQSRQALGVEYVDLYLIHWPGPNR------- 116
Query: 442 TDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVE 621
Y++TW+A E L + V++IGVSNF L+ LL + TV P+VNQVE
Sbjct: 117 ------------SYIETWRAFEKLYEMKKVRAIGVSNFEPHHLDDLLANCTVPPMVNQVE 164
Query: 622 CHPYLNQKRLKEFCEARGVKITAYSPLG 705
HP+ QK L+ +C + + +TA+ PLG
Sbjct: 165 MHPHFQQKALRAYCAEKNIAVTAWRPLG 192
>UniRef50_Q5T2L2 Cluster: Aldo-keto reductase family 1 member C-like
protein 1; n=14; Eutheria|Rep: Aldo-keto reductase
family 1 member C-like protein 1 - Homo sapiens (Human)
Length = 302
Score = 163 bits (395), Expect = 5e-39
Identities = 93/214 (43%), Positives = 123/214 (57%), Gaps = 5/214 (2%)
Frame = +1
Query: 82 VEFNNELKCPILGLGTWK---SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 252
V N+ P+LG GT+ + + +A K AID+G+RHID AY+Y NE+EVG+AI
Sbjct: 11 VRLNDGPFMPVLGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEVGQAIWE 70
Query: 253 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDG- 429
KI +G V RE++F T KLW TF R +LV AL+ +L L Y+DL++IH P A K+ G
Sbjct: 71 KIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFAMKQPGK 130
Query: 430 SLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVV 609
L P D SG+I V+ DTW+ L K GL KP
Sbjct: 131 ELLPKDASGEIILETVELCDTWELELILNKPGL---------------------RYKPTC 169
Query: 610 NQ-VECHPYLNQKRLKEFCEARGVKITAYSPLGS 708
NQ VECHPYLNQ +L EFC+++ + + AYS LGS
Sbjct: 170 NQVVECHPYLNQSKLLEFCKSKDIVLVAYSALGS 203
>UniRef50_Q838E0 Cluster: Oxidoreductase, aldo/keto reductase
family; n=24; Bacilli|Rep: Oxidoreductase, aldo/keto
reductase family - Enterococcus faecalis (Streptococcus
faecalis)
Length = 279
Score = 162 bits (394), Expect = 7e-39
Identities = 87/207 (42%), Positives = 118/207 (57%)
Frame = +1
Query: 82 VEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 261
V NN K P +GLG ++ E + V++ I GYR ID A +YGNE G I + +
Sbjct: 9 VTLNNGTKIPGMGLGVFQIPDEETAKVVEEGIINGYRLIDTAQIYGNESGTGAGIKAGLA 68
Query: 262 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 441
+ REDLF+TSK+WN D A ++L+ L + YLDLYLIHWP
Sbjct: 69 ATGLNREDLFVTSKVWNAHISYDETIQAFNDSLERLGLDYLDLYLIHWP----------- 117
Query: 442 TDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVE 621
+ Y ++W+A+E L EG VK+IGVSNF LE LL +A V PV+NQVE
Sbjct: 118 ---------GNNSYKESWQALETLYAEGKVKAIGVSNFQVHHLEDLLSYAKVVPVINQVE 168
Query: 622 CHPYLNQKRLKEFCEARGVKITAYSPL 702
HP L+QK +++FCE +K+ A+SPL
Sbjct: 169 LHPKLDQKEVRDFCEKHDIKVQAWSPL 195
>UniRef50_UPI00015B5BD7 Cluster: PREDICTED: similar to aldo-keto
reductase; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to aldo-keto reductase - Nasonia vitripennis
Length = 310
Score = 162 bits (393), Expect = 9e-39
Identities = 89/214 (41%), Positives = 134/214 (62%), Gaps = 3/214 (1%)
Frame = +1
Query: 82 VEFNNELKCPILGLGTWKSKPGEVTQAVKD-AIDIGYRHIDCAYVYGNEKEVGEAITSKI 258
+ NN P++G+GT+K + EV + V D + +G+R ID A VY NE+++G A+ +
Sbjct: 26 LRLNNGYDMPLVGIGTYKVRGREVIKRVIDESFAVGFRSIDTAVVYRNEEDIGLALKELL 85
Query: 259 KEGVVTREDLFITSKLWNTFHR-PDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSL 435
+ + RED+FITSKL + + PD +R +++++L L+ YLDLYLIHWP A + L
Sbjct: 86 PKYNLKREDIFITSKLSPSDNGDPDKIRKSVEDSLKALDTSYLDLYLIHWPGASR---IL 142
Query: 436 FPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHAT-VKPVVN 612
+ + K++ V TW + L ++GL++SIGVSN+ LE LL+H + VKP VN
Sbjct: 143 ENSPDNPKLR------VTTWATLVELQQKGLLRSIGVSNYTVGHLEHLLEHCSGVKPDVN 196
Query: 613 QVECHPYLNQKRLKEFCEARGVKITAYSPLGSPD 714
QVECHP+ Q L EFC +G+ + AYS LG+ D
Sbjct: 197 QVECHPHFRQDELIEFCTKQGIHVQAYSSLGTSD 230
>UniRef50_UPI00015B4912 Cluster: PREDICTED: similar to aldo-keto
reductase; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to aldo-keto reductase - Nasonia vitripennis
Length = 353
Score = 161 bits (391), Expect = 2e-38
Identities = 85/204 (41%), Positives = 122/204 (59%), Gaps = 3/204 (1%)
Frame = +1
Query: 109 PILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 288
PI+GLGT + + A++ G HID ++VY NE+ +G+ + +G RED+
Sbjct: 40 PIVGLGTHGLNEDVLETVLTGALEKGIGHIDTSFVYKNEETIGKVLKDWFAKGG-KREDI 98
Query: 289 FITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA--YKEDGSLFPTDQSGKI 462
F+TSKL + P+ V ++ +L+ L +QYLD+YLIH P A +KED T++ G +
Sbjct: 99 FVTSKLPYYDNHPESVEKYIKLSLEKLGLQYLDMYLIHAPFAVHHKEDSYELATNEDGSV 158
Query: 463 QF-SDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLN 639
+ D + WK ME VKEG KSIG+SNFN Q+ +L+ A +KP QVE H Y
Sbjct: 159 VLDTQTDPIAVWKEMEKQVKEGRTKSIGLSNFNETQITNILKEAKIKPSNLQVEVHAYHQ 218
Query: 640 QKRLKEFCEARGVKITAYSPLGSP 711
QK L EFC+ G+ +T Y+PLGSP
Sbjct: 219 QKPLIEFCQKNGIIVTGYAPLGSP 242
>UniRef50_A3LTU8 Cluster: D-arabinose dehydrogenase; n=5;
Saccharomycetales|Rep: D-arabinose dehydrogenase -
Pichia stipitis (Yeast)
Length = 326
Score = 161 bits (390), Expect = 2e-38
Identities = 92/225 (40%), Positives = 136/225 (60%), Gaps = 11/225 (4%)
Frame = +1
Query: 67 SSVPFVEFNNELKCPILGLGTWKSK-PGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEA 243
+ V FV +N P LGLGT + P E+ + V A+ GYRHID A+ YG E+ +G+A
Sbjct: 6 TDVDFV-LSNGKTIPALGLGTVPPEDPHELKEQVITAVKAGYRHIDTAWYYGTEEYIGQA 64
Query: 244 ITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKE 423
+ +EG+V REDLFIT+K+W +F R +L ++L +L + Y+DL+L HWP
Sbjct: 65 LKQLFEEGIVKREDLFITTKVWPSFWRNP--EKSLDKSLADLGLDYVDLFLQHWPVVLHG 122
Query: 424 DGSLF---PTDQSGKIQFSD-----VDYVDTWKAMEPLV-KEGLVKSIGVSNFNSKQLER 576
D + P D+ GK+ + D + Y+D + ++E ++ VKSIGVSN++ +L +
Sbjct: 123 DENGLPPQPRDKDGKLIYDDDPVSGIKYIDAYHSLEDIMDNTSKVKSIGVSNYSIPKLRK 182
Query: 577 LLQHATV-KPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGS 708
LL KPVVNQ+E HP L Q+ L ++C GV I+AYSP+GS
Sbjct: 183 LLAAVRKHKPVVNQIEYHPLLPQQDLVKYCYDNGVHISAYSPVGS 227
>UniRef50_A7CWF9 Cluster: Aldehyde reductase; n=2; Bacteria|Rep:
Aldehyde reductase - Opitutaceae bacterium TAV2
Length = 347
Score = 160 bits (389), Expect = 3e-38
Identities = 82/208 (39%), Positives = 118/208 (56%), Gaps = 5/208 (2%)
Frame = +1
Query: 103 KCPILGLGTWKSK---PGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV- 270
+ P +G+GT+ S PGEV +V A ++GYRH DCA VY NE+E+G +
Sbjct: 26 RMPAIGMGTFGSDHAAPGEVAASVYAAAELGYRHFDCAAVYSNEREIGATFRRILTSNTG 85
Query: 271 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP-QAYKEDGSLFPTD 447
+ REDL+ITSKLWN H V A +++L +L + YLDLYLIHWP + G +
Sbjct: 86 IRREDLWITSKLWNDKHAEADVIPAFEKSLRDLGLDYLDLYLIHWPFPNFHPPGCDVSSR 145
Query: 448 QSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECH 627
+ +++ TW+ +E L GLV+ IG SN +L+ LL+ A V+P VN++E H
Sbjct: 146 SPDARPYIHAEFMKTWRQLETLHDRGLVRHIGTSNMTIAKLQLLLRDARVRPAVNEMELH 205
Query: 628 PYLNQKRLKEFCEARGVKITAYSPLGSP 711
P+ Q L ++ R + Y PLGSP
Sbjct: 206 PHFQQPALFDYVRVRNIVPVGYCPLGSP 233
>UniRef50_Q01HB5 Cluster: OSIGBa0136O08-OSIGBa0153H12.9 protein;
n=4; Oryza sativa|Rep: OSIGBa0136O08-OSIGBa0153H12.9
protein - Oryza sativa (Rice)
Length = 337
Score = 159 bits (387), Expect = 5e-38
Identities = 92/220 (41%), Positives = 130/220 (59%), Gaps = 6/220 (2%)
Frame = +1
Query: 67 SSVPFVEFNNELKCPILGLGTWKSKP-GEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEA 243
++VP V N+ P+LG GT S P ++ + A+ +GYRH+D A VYG E VG A
Sbjct: 18 TAVPCVTLNSGHAMPVLGFGTGSSTPPADLAATIAHAVRLGYRHLDTAAVYGTEGAVGAA 77
Query: 244 ITSKIKEGVV-TREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAY- 417
+ ++ G V +R +LF+T+KL P V AL+E+L L + Y+DL+LIHWP A
Sbjct: 78 VAEAVRCGAVASRGELFVTTKLSMADAHPPRVVAALRESLSRLGLDYVDLFLIHWPVAIG 137
Query: 418 KED--GSLFPTDQS-GKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQH 588
K+D G L D S G + F D W+ ME + GL +SIGVSNF++ ++ RLL
Sbjct: 138 KKDAAGELTWDDLSRGLVPF---DMEGVWRGMEECHRLGLARSIGVSNFSAAKMSRLLAL 194
Query: 589 ATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGS 708
A V P VNQVE + Q++++E C GV + AYSPLG+
Sbjct: 195 AAVPPAVNQVEMNVGWRQEKVREVCGEGGVVVAAYSPLGA 234
>UniRef50_Q4PDR0 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 339
Score = 159 bits (387), Expect = 5e-38
Identities = 87/227 (38%), Positives = 134/227 (59%), Gaps = 14/227 (6%)
Frame = +1
Query: 67 SSVPFVEFNNELKCPILGLGTWKSKPG-----EVTQAVKDAIDIGYRHIDCAYVYGNEKE 231
+++P N K P +G+G W+ +PG E+ A+ AI +GYRH+D A Y NE E
Sbjct: 3 ANIPSFTLNTGAKLPSVGMGCWQGQPGPGRDNELVDALVRAIKVGYRHLDTATGYRNEAE 62
Query: 232 VGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQE---TLDNLNVQYLDLYLIH 402
VG+A+ ++ V R ++F+T+KL RP V +QE +L+ L + Y+DL+L+H
Sbjct: 63 VGQAV----RQSGVARSEIFVTTKL-----RPGGVHDVVQELENSLNELGIDYIDLWLLH 113
Query: 403 WPQAYKEDGSLFPTDQSGKIQFSD---VDYVDTWKAMEPLV---KEGLVKSIGVSNFNSK 564
WPQ + +D F T +S ++ + +TW ME + +G VK+IGVSNF+ K
Sbjct: 114 WPQGFTKDDGGFGTGESFGLEHQKHLGPTFNETWAKMEDVFLNSHKGKVKAIGVSNFSIK 173
Query: 565 QLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLG 705
LE L + + V P VNQ+E HPYL + L ++C+ + + +TAYSPLG
Sbjct: 174 NLEILAKTSKVTPAVNQIEAHPYLPEHELVKYCKHKSIHVTAYSPLG 220
>UniRef50_Q9ZBW7 Cluster: Putative oxidoreductase; n=2;
Actinomycetales|Rep: Putative oxidoreductase -
Streptomyces coelicolor
Length = 277
Score = 159 bits (386), Expect = 6e-38
Identities = 89/214 (41%), Positives = 120/214 (56%)
Frame = +1
Query: 67 SSVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAI 246
S VP + NN ++ P LG G W+ + AV A++ GYR ID A +YGNE+ G AI
Sbjct: 3 SKVPPIILNNGVEMPQLGFGVWQVPDDDAQTAVALALEAGYRSIDTAAIYGNEEGTGRAI 62
Query: 247 TSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKED 426
+ + REDLF+T+KLWN+ D A ++ L ++YLDLYLIHWP KE
Sbjct: 63 AAS----GLAREDLFVTTKLWNSDQGYDSTLRAFDTSMAKLGLEYLDLYLIHWPMPAKE- 117
Query: 427 GSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPV 606
YVDT+KA E L+ +G V++IGVSNF + LERL +V P
Sbjct: 118 -----------------RYVDTYKAFEKLLADGRVRAIGVSNFLPEHLERLTAETSVIPA 160
Query: 607 VNQVECHPYLNQKRLKEFCEARGVKITAYSPLGS 708
VNQ+E HP+L Q +E +G+ A+SPLGS
Sbjct: 161 VNQIELHPHLQQHAAREVHAEQGIATEAWSPLGS 194
>UniRef50_Q7G764 Cluster: Probable NAD(P)H-dependent oxidoreductase
1; n=32; Eukaryota|Rep: Probable NAD(P)H-dependent
oxidoreductase 1 - Oryza sativa subsp. japonica (Rice)
Length = 321
Score = 159 bits (386), Expect = 6e-38
Identities = 85/220 (38%), Positives = 133/220 (60%), Gaps = 5/220 (2%)
Frame = +1
Query: 64 MSSVPFVEFNNELKC-PILGLGTWK---SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKE 231
M+++P V + ++ P +G+GT + + T A+ AI++GYRH D A +Y E
Sbjct: 1 MATIPEVPASELIQTMPRVGMGTAAFPFTSSEDTTAAMLRAIELGYRHFDTARIYATEGC 60
Query: 232 VGEAITSKIKEGVV-TREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 408
VGEA+ ++ G++ +R D+F+TSK+W + V A +ETL NL + Y+DL L+HWP
Sbjct: 61 VGEAVAEAVRRGLIASRADVFVTSKIWCSDLHAGRVVPAARETLRNLGMDYVDLLLVHWP 120
Query: 409 QAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQH 588
+ FP + + D++ V W+ ME + GL ++IGVSNF++K+LE+LL
Sbjct: 121 VSLTPGNYDFPFPKEVILPSFDMEGV--WRGMEECHRLGLARAIGVSNFSAKKLEQLLSL 178
Query: 589 ATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGS 708
A V+P VNQVE +P Q+ L+E C GV++ YSPLG+
Sbjct: 179 AAVRPAVNQVEVNPMWQQRTLREVCRREGVQLCGYSPLGA 218
>UniRef50_UPI00006CD296 Cluster: oxidoreductase, aldo/keto reductase
family protein; n=1; Tetrahymena thermophila SB210|Rep:
oxidoreductase, aldo/keto reductase family protein -
Tetrahymena thermophila SB210
Length = 295
Score = 158 bits (383), Expect = 1e-37
Identities = 83/207 (40%), Positives = 124/207 (59%), Gaps = 1/207 (0%)
Frame = +1
Query: 85 EFNNELKCPILGLGTWKS-KPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 261
E N K P+ GLGT+K E+ ++ A+D+GYRHID A +Y NEK++G+A+ K
Sbjct: 9 ELCNGSKLPVFGLGTYKVVSKEEMVTFLRTALDLGYRHIDTAIMYENEKQIGDALQEIYK 68
Query: 262 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 441
EG REDLF+ +KL++ ++ V ++++L NL Y+DLYL+H+ S P
Sbjct: 69 EGKYKREDLFLVTKLFS--NKNTKVEDQVRQSLQNLQTNYIDLYLLHY-------ASSPP 119
Query: 442 TDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVE 621
TDQ + + W E LV++GL+++IG+SNFN + L L + +KPVVNQ+E
Sbjct: 120 TDQ---FELTHKPVFQVWAEFEELVQKGLIRNIGISNFNVQMLLDLYSYCKIKPVVNQIE 176
Query: 622 CHPYLNQKRLKEFCEARGVKITAYSPL 702
+ Y Q RL EFC+ + +TAY PL
Sbjct: 177 VNVYCQQPRLLEFCKKLNLHVTAYCPL 203
>UniRef50_Q7N0E4 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=2; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase
A - Photorhabdus luminescens subsp. laumondii
Length = 292
Score = 158 bits (383), Expect = 1e-37
Identities = 85/213 (39%), Positives = 121/213 (56%)
Frame = +1
Query: 64 MSSVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEA 243
M + P + + P LGLG+W S ++ + + A+DIGYR ID A +Y NEK VG A
Sbjct: 1 MDNQPIIRLADGNHMPQLGLGSWASDDQQIAETIHAALDIGYRAIDTAAIYNNEKGVGNA 60
Query: 244 ITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKE 423
++E + RED+F+T+KLWN H R AL E+L+ L + Y+DLYLIHWP
Sbjct: 61 ----LQETDIPREDIFVTTKLWNDRHLD--ARAALTESLEKLQLDYVDLYLIHWPAP--- 111
Query: 424 DGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKP 603
P DQ YV W+ + L KEGL++SIGVSNF + ++RL+ V P
Sbjct: 112 -----PQDQ----------YVGAWQQLIELQKEGLIRSIGVSNFQPEHIQRLINETGVHP 156
Query: 604 VVNQVECHPYLNQKRLKEFCEARGVKITAYSPL 702
V+NQ+E HP L Q++L + + ++SPL
Sbjct: 157 VINQIELHPLLQQRQLHAWNATHNIVTESWSPL 189
>UniRef50_Q968S3 Cluster: Aldoketoreductase-like protein; n=1;
Orconectes limosus|Rep: Aldoketoreductase-like protein -
Orconectes limosus (Spinycheek crayfish)
Length = 336
Score = 158 bits (383), Expect = 1e-37
Identities = 84/223 (37%), Positives = 127/223 (56%), Gaps = 7/223 (3%)
Frame = +1
Query: 64 MSSVPFVEFNNELKCPILGLGTW------KSKPGEVTQAVKDAIDIGYRHIDCAYVYGNE 225
M+ +P + N+ P++GLGT K VT ++ A++ GYRH D A YGNE
Sbjct: 8 MTKIPTILLNSGSHIPVMGLGTGSLGRNGKMSEEAVTAVLETALECGYRHFDSAAYYGNE 67
Query: 226 KEVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHW 405
+G+ + I EG V RE+LFIT+KL +R V LQ++LDNL + Y+DLYL+H+
Sbjct: 68 AIIGQVLRRWISEGKVKREELFITTKLPTRGNREKDVARFLQKSLDNLRLPYVDLYLVHY 127
Query: 406 PQAYKE-DGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLL 582
P + D D+ +D+ + W+AME + G K+IG+SNFN+ Q++R++
Sbjct: 128 PCGILDTDRERLSADEVTVDPTTDIHAI--WRAMEAQLAAGKTKNIGLSNFNADQVQRII 185
Query: 583 QHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSP 711
+ V+P V QVE H Y+ Q L+ FC + + A+ PLG P
Sbjct: 186 KGCQVRPAVLQVEVHVYMQQGALRAFCAQHDIVVCAFCPLGGP 228
>UniRef50_Q7G765 Cluster: Probable NAD(P)H-dependent oxidoreductase
2; n=6; Magnoliophyta|Rep: Probable NAD(P)H-dependent
oxidoreductase 2 - Oryza sativa subsp. japonica (Rice)
Length = 322
Score = 157 bits (381), Expect = 3e-37
Identities = 87/220 (39%), Positives = 128/220 (58%), Gaps = 5/220 (2%)
Frame = +1
Query: 64 MSSVPFVEFNNELKC-PILGLGTWK---SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKE 231
M+++P V + L P +G+GT + E T A+ AI++GYRH D A +Y E
Sbjct: 3 MATIPEVPASALLPTMPRIGMGTAAFPFTSSEETTAALLRAIELGYRHFDTARLYATEGC 62
Query: 232 VGEAITSKIKEGVV-TREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 408
V EA+ ++ G+V +R D+F+TSKLW + V A +ETL NL + Y+DL L+HWP
Sbjct: 63 VSEAVAEAVRRGLVASRADVFVTSKLWCSDLHAGRVVPAARETLRNLGMDYVDLLLVHWP 122
Query: 409 QAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQH 588
FP + D++ V W+ ME + GL ++IGVSNF++K+LE+LL
Sbjct: 123 ATVAPGSYDFPFPKEEMAPAFDMEGV--WRGMEECHRLGLARAIGVSNFSAKKLEQLLSF 180
Query: 589 ATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGS 708
A V+P NQVE +P Q+ L+E C GV++ YSPLG+
Sbjct: 181 AVVRPAANQVEMNPMWQQRTLREVCRREGVQLCGYSPLGA 220
>UniRef50_Q4FY75 Cluster: Aldo-keto reductase-like protein; n=5;
Trypanosomatidae|Rep: Aldo-keto reductase-like protein -
Leishmania major strain Friedlin
Length = 372
Score = 157 bits (380), Expect = 3e-37
Identities = 90/213 (42%), Positives = 116/213 (54%), Gaps = 12/213 (5%)
Frame = +1
Query: 109 PILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 288
P LG GT++ E T AV A+ GYRH+DCA YGNE VGEA+ ++ REDL
Sbjct: 31 PQLGFGTYRLPVSEATDAVAFALSCGYRHVDCAKAYGNEAAVGEALAQALRTRCTRREDL 90
Query: 289 FITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA------YKEDGSLFPTDQ 450
F+TSKLW T PD V A + TL L + YLDLYLIHWP + D +P +
Sbjct: 91 FVTSKLWPTDQHPDHVEAACRATLAALQLDYLDLYLIHWPVCMRHTPHWTSDEDRYPRHR 150
Query: 451 SGKIQF-SDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQH-ATVK----PVVN 612
G + V +DTW AM LV GLVKSIG++N + + L++ A K PV+N
Sbjct: 151 DGTPAIDTSVTLLDTWTAMNRLVDRGLVKSIGLANCTTAHVNDLVKAVAEAKLAHLPVLN 210
Query: 613 QVECHPYLNQKRLKEFCEARGVKITAYSPLGSP 711
QVE HP + L + + + AY PLG P
Sbjct: 211 QVEHHPGIVDGDLIGCLGSHDMLMAAYCPLGMP 243
>UniRef50_Q4P4P1 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 322
Score = 155 bits (377), Expect = 8e-37
Identities = 83/208 (39%), Positives = 119/208 (57%), Gaps = 1/208 (0%)
Frame = +1
Query: 82 VEFNNELKCPILGLGTWKS-KPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 258
++ NN + P + LG +K+ G A K A D GYRHID A Y NE+ VG A+
Sbjct: 19 IKLNNGQEIPQVALGVYKAPNDGSTENACKWAFDAGYRHIDSAARYMNEESVGRALAEWT 78
Query: 259 KEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLF 438
KE V R ++FITSKLW+ H D A++++L LNV Y+D+YL+H P + L
Sbjct: 79 KENNVPRSEIFITSKLWDADH--DKAAAAIEDSLKKLNVDYMDMYLMHSPGTMGAEKRL- 135
Query: 439 PTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQV 618
+ WKA+E V G +K+IGVSNF+ ++L+ LL + +KP VNQ+
Sbjct: 136 ----------------EAWKALEEAVDAGKIKTIGVSNFDVEELDHLLANCRIKPAVNQI 179
Query: 619 ECHPYLNQKRLKEFCEARGVKITAYSPL 702
E HP+ + L+E C +RG+ I AYSP+
Sbjct: 180 ESHPFFAHEELREACISRGIHIQAYSPM 207
>UniRef50_A2QB88 Cluster: Contig An01c0460, complete genome.
precursor; n=1; Aspergillus niger|Rep: Contig An01c0460,
complete genome. precursor - Aspergillus niger
Length = 351
Score = 155 bits (376), Expect = 1e-36
Identities = 94/216 (43%), Positives = 124/216 (57%), Gaps = 12/216 (5%)
Frame = +1
Query: 94 NELKCPILGLGTWKSKPGE--VTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEG 267
+E+ P +GLGT++ G V +AV A+ GYRHID A YGNE EVGEAI KE
Sbjct: 42 SEMTFPAVGLGTFQGDAGNRGVKEAVLQALRCGYRHIDTATAYGNEIEVGEAI----KES 97
Query: 268 VVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQY-LDLYLIHW-----PQAYKE-- 423
+ RE++ +T+KL T+HR V AL +L+ L + Y L ++L P AY
Sbjct: 98 RIPREEIIVTTKLAQTWHRVSDVERALDLSLERLQLNYGLSMHLYSASSYSVPHAYSPGP 157
Query: 424 DGSLFPTDQSGKIQFSDV--DYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATV 597
D + I ++ DY TW AME LV +G +K IGVSNFN +LERLL A +
Sbjct: 158 DNNTIRHPNGKPIIDHELSRDYPSTWAAMESLVDKGKLKMIGVSNFNILKLERLLGSARI 217
Query: 598 KPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLG 705
P VNQ+E HPYL Q L FC+A G+ + A+ PLG
Sbjct: 218 PPAVNQIELHPYLPQVELVRFCKANGIHLVAHQPLG 253
>UniRef50_Q5FK98 Cluster: Oxidoreductase; n=8; Lactobacillales|Rep:
Oxidoreductase - Lactobacillus acidophilus
Length = 285
Score = 152 bits (369), Expect = 7e-36
Identities = 83/207 (40%), Positives = 126/207 (60%), Gaps = 1/207 (0%)
Frame = +1
Query: 91 NNELKCPILGLGTWKSKPGEVTQ-AVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEG 267
NN +K PI+G GTW++ GEV + +V A++ GYRHID A YGNE VG AI K G
Sbjct: 13 NNGVKIPIIGFGTWQTPDGEVAEESVLAALNCGYRHIDTASAYGNEDSVGRAIQ---KSG 69
Query: 268 VVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTD 447
+ R +LFIT+KLWN+ H + + A+ ++L +L + YLD+YLIHW P
Sbjct: 70 I-NRHELFITTKLWNSDHGYEKTKKAIDQSLLDLKLDYLDMYLIHW-----------PNP 117
Query: 448 QSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECH 627
S + +++++ ++W+AME V+ G +++IGVSNF L+ L++ A +KPVVNQ+ +
Sbjct: 118 SSMRDHWAEIN-AESWRAMEEAVRAGKIRAIGVSNFRKHHLDALMETAEIKPVVNQIFLN 176
Query: 628 PYLNQKRLKEFCEARGVKITAYSPLGS 708
P Q + + + AYSPLG+
Sbjct: 177 PSDLQSEVVTENKKLDLLSEAYSPLGT 203
>UniRef50_A6LZ55 Cluster: 2,5-didehydrogluconate reductase; n=1;
Clostridium beijerinckii NCIMB 8052|Rep:
2,5-didehydrogluconate reductase - Clostridium
beijerinckii NCIMB 8052
Length = 289
Score = 152 bits (369), Expect = 7e-36
Identities = 81/205 (39%), Positives = 120/205 (58%), Gaps = 1/205 (0%)
Frame = +1
Query: 94 NELKCPILGLGTWKSKPGEVTQ-AVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 270
N +K P +G G +K GE + AV +AI IGYRH D A +YGNEK++G AI ++
Sbjct: 12 NGIKIPQVGFGVYKLNKGEDFETAVGEAIKIGYRHFDTAKIYGNEKDLGLAI----EKSQ 67
Query: 271 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQ 450
+ RE+ FITSK+WNT H + + A ++T LNV+YLD+YLIH+ +Y
Sbjct: 68 IPREEFFITSKVWNTDHGYEATKKAFEQTCKKLNVEYLDMYLIHFASSY----------- 116
Query: 451 SGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHP 630
Y++TW AME L +G +K IGV+NF + LE L++H+ + P++NQ+E HP
Sbjct: 117 ----------YLETWHAMEELYLQGKIKVIGVANFQIQHLEELMKHSRITPMINQIETHP 166
Query: 631 YLNQKRLKEFCEARGVKITAYSPLG 705
Q L ++ + A++PLG
Sbjct: 167 EFPQNELHQYLTKHKILHEAWAPLG 191
>UniRef50_A6WDZ5 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:
Aldo/keto reductase - Kineococcus radiotolerans SRS30216
Length = 343
Score = 151 bits (367), Expect = 1e-35
Identities = 81/217 (37%), Positives = 116/217 (53%), Gaps = 4/217 (1%)
Frame = +1
Query: 73 VPFVEFNNELKCPILGLGTWKS---KPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEA 243
VP E P +G+GT+ S P EV AV A+ GYR +DCA VYGNE +VGEA
Sbjct: 13 VPRRELRGGATVPAIGIGTFGSDRYSPAEVAAAVAGAVAAGYRLVDCAAVYGNEAQVGEA 72
Query: 244 ITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKE 423
+ + GV R++LF+ SK+WN H P ++ +L +L + +LD +HWP
Sbjct: 73 LAGAVAGGV-DRDELFVVSKVWNDAHAPADAVASVHRSLRDLRLDHLDAVFVHWPFPNHH 131
Query: 424 DGSLFPTDQSGKIQFSDVD-YVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVK 600
+ + + D D Y+ W A+E LV GLV+ +G SN +L+ LL+ A +
Sbjct: 132 PPMADTDARDPRARPYDHDAYLALWGALEGLVDSGLVRHLGTSNTTVAKLDLLLRDARIP 191
Query: 601 PVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSP 711
P +N++E HP Q L C G++ YSPLGSP
Sbjct: 192 PALNEMELHPCFQQPELFAHCVRHGIQPVGYSPLGSP 228
>UniRef50_P06632 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=8; Actinomycetales|Rep: 2,5-diketo-D-gluconic acid
reductase A - Corynebacterium sp. (strain ATCC 31090)
Length = 278
Score = 149 bits (361), Expect = 7e-35
Identities = 82/212 (38%), Positives = 117/212 (55%)
Frame = +1
Query: 70 SVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAIT 249
+VP + N+ P LG G +K P + +AV++A+++GYRHID A +YGNE+ VG AI
Sbjct: 2 TVPSIVLNDGNSIPQLGYGVFKVPPADTQRAVEEALEVGYRHIDTAAIYGNEEGVGAAIA 61
Query: 250 SKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDG 429
+ + R+DLFIT+KLWN H D A+ E+L L + +DLYL+HWP +
Sbjct: 62 A----SGIARDDLFITTKLWNDRHDGDEPAAAIAESLAKLALDQVDLYLVHWPTPAAD-- 115
Query: 430 SLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVV 609
+YV W+ M L GL +SIGVSN LER++ V P V
Sbjct: 116 ----------------NYVHAWEKMIELRAAGLTRSIGVSNHLVPHLERIVAATGVVPAV 159
Query: 610 NQVECHPYLNQKRLKEFCEARGVKITAYSPLG 705
NQ+E HP Q+ + ++ A VKI ++ PLG
Sbjct: 160 NQIELHPAYQQREITDWAAAHDVKIESWGPLG 191
>UniRef50_Q1VRG6 Cluster: YvgN; n=1; Psychroflexus torquis ATCC
700755|Rep: YvgN - Psychroflexus torquis ATCC 700755
Length = 280
Score = 147 bits (356), Expect = 3e-34
Identities = 85/207 (41%), Positives = 123/207 (59%), Gaps = 3/207 (1%)
Frame = +1
Query: 91 NNELKCPILGLGTWKSKPGEVTQAV-KDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEG 267
N+ + PI+G GT+K+ E +++ K A+ +GYR ID +Y NE+ VG+AI ++ G
Sbjct: 6 NDGNRIPIVGFGTYKANEEEGIKSIQKSALTLGYRLIDTVAIYQNEEAVGKAIKAR---G 62
Query: 268 VVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTD 447
V+ RE++F+T+KLW R AL E+L L++ Y+DLYLIHWP
Sbjct: 63 VL-REEIFVTTKLWRENLGYKQTRIALDESLRKLDLNYIDLYLIHWP------------- 108
Query: 448 QSGKIQFSD--VDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVE 621
+ I + D DTW+AME L EG +KS+GVSNF + LE L Q A V P VNQ+E
Sbjct: 109 -ANAINYKDWQKTNADTWRAMEELQAEGKIKSLGVSNFWPEHLEALFQTAKVSPSVNQIE 167
Query: 622 CHPYLNQKRLKEFCEARGVKITAYSPL 702
HP Q ++ EFC+ G+ + ++SPL
Sbjct: 168 FHPGYWQPQVTEFCKNHGIAVESWSPL 194
>UniRef50_Q24C22 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=4; Oligohymenophorea|Rep: Oxidoreductase,
aldo/keto reductase family protein - Tetrahymena
thermophila SB210
Length = 297
Score = 147 bits (356), Expect = 3e-34
Identities = 82/211 (38%), Positives = 121/211 (57%), Gaps = 1/211 (0%)
Frame = +1
Query: 73 VPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 252
VP + F P +G GT++ + + V +A+ IGY HID A VY NE+++ + I +
Sbjct: 13 VPILNFREGGSIPQIGYGTYELRQNDCIIGVTEALKIGYTHIDTASVYRNEQDIAKVIHN 72
Query: 253 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGS 432
+ REDLFITSK+ + + A+Q+ L LN++YLD LIHWP K
Sbjct: 73 PAYG--IKREDLFITSKISPGEQGYEQAKKAVQDMLTRLNIKYLDCVLIHWPGVSK---- 126
Query: 433 LFPTD-QSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVV 609
L P D ++ +I+ ++TWKA+ L K G++K IGVSNFN L+ L++ + KP +
Sbjct: 127 LPPNDPKNAQIR------LETWKALIELRKAGVIKHIGVSNFNINHLQHLIEKSEFKPEM 180
Query: 610 NQVECHPYLNQKRLKEFCEARGVKITAYSPL 702
NQ E HP K+ EFC+ G+ + AYSPL
Sbjct: 181 NQFEIHPLCFNKKTIEFCQKNGILVEAYSPL 211
>UniRef50_Q4PHK0 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 355
Score = 147 bits (356), Expect = 3e-34
Identities = 89/237 (37%), Positives = 124/237 (52%), Gaps = 29/237 (12%)
Frame = +1
Query: 85 EFNNELKCPILGLGTWKSKPGEVTQAVKDAID-----------------IGYRHI----- 198
+ N + P++GLGTW+S PGEV +AV+ AI +GY +
Sbjct: 15 KLNTGAEIPVIGLGTWQSAPGEVAKAVESAIKAGYRHIVSMLTSLLTLTLGYVALHPLYI 74
Query: 199 -----DCAYVYGNEKEVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLD 363
D A++YGNE EVG+ I K V R +LF+T+K+W T+HR L E+L
Sbjct: 75 PFLAKDAAWIYGNENEVGQGI----KASGVPRSELFVTTKIWCTYHRQP--EACLDESLQ 128
Query: 364 NLNVQYLDLYLIHWP-QAYKEDGSLFPTDQSGKIQFS-DVDYVDTWKAMEPLVKEGLVKS 537
L + Y+DL L+HWP K P ++ G D TW+ ME L G K+
Sbjct: 129 RLGLDYVDLLLVHWPVPLVKRGDEKIPLNEDGSRAIDRDWSPEQTWELMEKLPATGKTKA 188
Query: 538 IGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGS 708
IGVSN++ L++LL A + P NQVE HP+L Q L ++C +G+ AYSPLGS
Sbjct: 189 IGVSNWSIAFLDKLLAKAKIVPAANQVELHPFLPQHELVKYCHDKGILPQAYSPLGS 245
>UniRef50_Q7NB44 Cluster: ARA1; n=3; Firmicutes|Rep: ARA1 -
Mycoplasma gallisepticum
Length = 289
Score = 147 bits (355), Expect = 4e-34
Identities = 82/216 (37%), Positives = 125/216 (57%), Gaps = 1/216 (0%)
Frame = +1
Query: 55 TVKMSSVPFVEFNNELKCPILGLGTWKSKPGEVT-QAVKDAIDIGYRHIDCAYVYGNEKE 231
T K+ + + N K P +G GT+K + G+ T +AVK A+++GYRH+DCA +Y N+
Sbjct: 5 TKKIKVMKYNLLANNYKMPSIGFGTYKLEDGKQTVEAVKTALEVGYRHLDCAEIYENQLS 64
Query: 232 VGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQ 411
V + I K V R+++FITSK+WN + + A + L +L+++YLDL LIHWP
Sbjct: 65 VSQGI----KLSGVNRKEIFITSKIWNDDKGYESTKKAFHKILKDLDLEYLDLLLIHWPI 120
Query: 412 AYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHA 591
G F K + +V+ TWKAME EG +K+IG+SNF +E L + A
Sbjct: 121 -----GKGF------KDNWQEVN-AQTWKAMEEFYLEGKIKAIGLSNFLVHHIEALKKSA 168
Query: 592 TVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSP 699
+ P+VNQ+E HP Q + E+C+ + + A+SP
Sbjct: 169 KILPMVNQLEFHPGYLQPEIVEYCQKNNIVVQAWSP 204
>UniRef50_A0JX62 Cluster: 2,5-didehydrogluconate reductase; n=9;
Bacteria|Rep: 2,5-didehydrogluconate reductase -
Arthrobacter sp. (strain FB24)
Length = 291
Score = 147 bits (355), Expect = 4e-34
Identities = 86/227 (37%), Positives = 123/227 (54%), Gaps = 13/227 (5%)
Frame = +1
Query: 64 MSSVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEA 243
M + P + NN + LG G +K P + V A++ GYRH D A +YGNE VG+A
Sbjct: 1 MKNSPRLSLNNGVLIDQLGFGLYKVPPADAAGLVTMALEAGYRHFDTAAMYGNETGVGKA 60
Query: 244 IT-------------SKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYL 384
I S ++REDLF+T+K+WN H D A ++ NL ++Y+
Sbjct: 61 IGALAGFAGGGPAGGSGEAAPSLSREDLFVTTKVWNDDHGYDATMRAFDTSMSNLGMEYV 120
Query: 385 DLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSK 564
DLYLIHWP A + LF ++++AME L +EG +++IGVSNF
Sbjct: 121 DLYLIHWPCARR---GLF---------------TESYRAMETLYREGRIRAIGVSNFQPA 162
Query: 565 QLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLG 705
LE LL+ A V P VNQ+E HP+L Q L++ + G++ A+SPLG
Sbjct: 163 HLEHLLETAEVVPAVNQIELHPWLQQDELRQLHDRLGIRTEAWSPLG 209
>UniRef50_Q88SL1 Cluster: Oxidoreductase; n=51; Lactobacillales|Rep:
Oxidoreductase - Lactobacillus plantarum
Length = 286
Score = 146 bits (354), Expect = 5e-34
Identities = 83/207 (40%), Positives = 115/207 (55%), Gaps = 1/207 (0%)
Frame = +1
Query: 91 NNELKCPILGLGTWKSKPGEVT-QAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEG 267
NN K PI+G GTW++ G+V +V A+ GYRHID A YGNE+ VG+AI +
Sbjct: 14 NNGTKIPIVGFGTWQTPDGQVAYDSVLAALKAGYRHIDTAAAYGNEESVGKAIA----DS 69
Query: 268 VVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTD 447
V REDLF+T+KLWN H D + AL +L L + Y+DLYLIHWP
Sbjct: 70 GVAREDLFVTTKLWNADHGYDAAKKALDTSLAKLGLDYVDLYLIHWPNP----------- 118
Query: 448 QSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECH 627
+ + + ++ DTW+AME ++IGVSNF K L+ LL+ A V P VNQ+ +
Sbjct: 119 AAMRDNWEQLN-ADTWRAMEEAYTARKARAIGVSNFRPKHLDALLKTAKVVPAVNQIFLN 177
Query: 628 PYLNQKRLKEFCEARGVKITAYSPLGS 708
P + + + + AYSPLG+
Sbjct: 178 PSDMEDEVVAYNRKHDILSEAYSPLGT 204
>UniRef50_A6NPD6 Cluster: Putative uncharacterized protein; n=3;
Bacteria|Rep: Putative uncharacterized protein -
Bacteroides capillosus ATCC 29799
Length = 287
Score = 145 bits (352), Expect = 8e-34
Identities = 82/205 (40%), Positives = 112/205 (54%)
Frame = +1
Query: 91 NNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 270
+N L P +G GT+K+ G+ + + +AI GYRH D A YG E +G+A+ E
Sbjct: 11 SNGLSIPAVGFGTYKTGDGD-SAVLSNAIAQGYRHFDTASFYGTETALGQAVA----ESD 65
Query: 271 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQ 450
+ RED F+TSKLW T D A TL+ L YLDLYLIHWP+ E D+
Sbjct: 66 IPREDFFLTSKLWKTEMGYDAALRAFDATLERLGTDYLDLYLIHWPRPDLELEDWAKLDR 125
Query: 451 SGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHP 630
+TW+A+E L + GLV++IGVSNF LE +L A V P+V+Q+E HP
Sbjct: 126 ------------ETWRALERLYESGLVRAIGVSNFLPHHLEPILASANVAPMVDQLEFHP 173
Query: 631 YLNQKRLKEFCEARGVKITAYSPLG 705
Q FC+ + + A+SPLG
Sbjct: 174 GYTQDEAVAFCQNHSILVEAWSPLG 198
>UniRef50_Q5FT75 Cluster: Putative 2,5-diketo-D-gluconic acid
reductase; n=1; Gluconobacter oxydans|Rep: Putative
2,5-diketo-D-gluconic acid reductase - Gluconobacter
oxydans (Gluconobacter suboxydans)
Length = 279
Score = 145 bits (351), Expect = 1e-33
Identities = 80/208 (38%), Positives = 114/208 (54%)
Frame = +1
Query: 82 VEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 261
+ F++ P +GLG W++ P E + VK+A+ +GYR +D A +Y NE+ VG+
Sbjct: 14 ISFHDGHTMPQIGLGVWETPPDETAEVVKEAVKLGYRSVDTARLYKNEEGVGK------- 66
Query: 262 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 441
G+ ++F+T+KLWN D A +E+ L LDLYLIHWP
Sbjct: 67 -GLEDHPEIFLTTKLWNDEQGYDSTLRAYEESARLLRRPVLDLYLIHWPMP--------- 116
Query: 442 TDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVE 621
+ YV+TWKA+ L K G VKSIGVSNF S+ LER++ V PVVNQ+E
Sbjct: 117 ---------AQGQYVETWKALVELKKSGRVKSIGVSNFESEHLERIMDATGVVPVVNQIE 167
Query: 622 CHPYLNQKRLKEFCEARGVKITAYSPLG 705
HP Q+ L+EF E ++ ++ PLG
Sbjct: 168 LHPDFQQRALREFHEKHNIRTESWRPLG 195
>UniRef50_Q6NII7 Cluster: Putative oxidoreductase; n=2;
Corynebacterium|Rep: Putative oxidoreductase -
Corynebacterium diphtheriae
Length = 290
Score = 144 bits (350), Expect = 1e-33
Identities = 76/214 (35%), Positives = 120/214 (56%)
Frame = +1
Query: 73 VPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 252
+P + N+ + P +G GT+K + + +AV+ AI++GYRHID A +Y NE+EVG A+
Sbjct: 11 IPTITLNDGTEMPAIGFGTYKLREQDAYRAVRSAIEVGYRHIDTASLYKNEEEVGRAVAD 70
Query: 253 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGS 432
I G V R++LFIT+K+WN H L + + QE+L L + Y+D ++HWP
Sbjct: 71 AITAGEVARDELFITTKVWNDMHGDQLTQRSFQESLHRLGLDYIDCCMVHWP-------- 122
Query: 433 LFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVN 612
+P Q G YV+++ A+ + G ++S+ V+NF + L ++ + PV+N
Sbjct: 123 -WP--QKGL-------YVESFAALAKIQGLGQLQSVAVANFYPEVLREIVAETGIAPVLN 172
Query: 613 QVECHPYLNQKRLKEFCEARGVKITAYSPLGSPD 714
QVE HP +Q + GV A+SPLG D
Sbjct: 173 QVELHPGFSQAEQRAVDRELGVVTEAWSPLGRGD 206
>UniRef50_Q18483 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 287
Score = 144 bits (350), Expect = 1e-33
Identities = 78/202 (38%), Positives = 115/202 (56%), Gaps = 1/202 (0%)
Frame = +1
Query: 109 PILGLGTWKSKPGEVTQAVKDA-IDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 285
P++G+GTW+ + E+ + V DA GYR ID A VY NE ++G + + + RED
Sbjct: 12 PLIGIGTWQVQKEEILRQVIDAGFKEGYRFIDTAQVYNNEAKIGRILEKLLPANGLKRED 71
Query: 286 LFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQ 465
++ITSKL + R +++E+L NL V+YLDL LIHWP GS ++ +
Sbjct: 72 IWITSKLAPSNAGVKKARESIEESLSNLKVEYLDLLLIHWP------GSSLKSENPANKK 125
Query: 466 FSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQK 645
V++W M ++ EG ++S+GVSNF LE L + + V P VNQVE HP+ +Q
Sbjct: 126 LR----VESWNVMCEMMAEGKLRSVGVSNFEICHLEELKKDSNVVPAVNQVEYHPHFHQD 181
Query: 646 RLKEFCEARGVKITAYSPLGSP 711
L ++C + AYS LGSP
Sbjct: 182 DLVKYCNENNIHFQAYSSLGSP 203
>UniRef50_Q9X0A2 Cluster: Oxidoreductase, aldo/keto reductase
family; n=21; Bacteria|Rep: Oxidoreductase, aldo/keto
reductase family - Thermotoga maritima
Length = 286
Score = 144 bits (349), Expect = 2e-33
Identities = 82/209 (39%), Positives = 118/209 (56%)
Frame = +1
Query: 73 VPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 252
VP V NN ++ PILG G ++ P + + V +AI +GYR ID A Y NE+ VG AI
Sbjct: 3 VPKVTLNNGVEMPILGYGVFQIPPEKTEECVYEAIKVGYRLIDTAASYMNEEGVGRAIKR 62
Query: 253 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGS 432
I EG+V RE+LF+T+KLW + + + A +++L L ++Y+DLYLIH P
Sbjct: 63 AIDEGIVRREELFVTTKLWVSDVGYESTKKAFEKSLKKLQLEYIDLYLIHQP-------- 114
Query: 433 LFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVN 612
F DV WKAME + K+GLV++IGVSNF +L L+ H + P VN
Sbjct: 115 -----------FGDVHC--AWKAMEEMYKDGLVRAIGVSNFYPDRLMDLMVHHEIVPAVN 161
Query: 613 QVECHPYLNQKRLKEFCEARGVKITAYSP 699
Q+E HP+ ++ EF ++ A+ P
Sbjct: 162 QIEIHPFYQRQEEIEFMRNYNIQPEAWGP 190
>UniRef50_Q03XK0 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=3; Lactobacillales|Rep: Aldo/keto
reductase of diketogulonate reductase family -
Leuconostoc mesenteroides subsp. mesenteroides (strain
ATCC 8293 /NCDO 523)
Length = 292
Score = 144 bits (349), Expect = 2e-33
Identities = 80/201 (39%), Positives = 116/201 (57%), Gaps = 1/201 (0%)
Frame = +1
Query: 100 LKCPILGLGTWK-SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVT 276
++ P+LG G ++ + G QAV DAI GYR ID A YGNE+EVGEAI I +G+V
Sbjct: 10 IEMPLLGFGVFQVQEKGAAKQAVLDAIKTGYRLIDTAASYGNEREVGEAILEAINQGIVK 69
Query: 277 REDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSG 456
RE+LF+TSK+W A+Q +L LN+ YLDLYLIH P
Sbjct: 70 REELFVTSKMWVQDVSAQQATAAIQSSLQRLNLDYLDLYLIHQP---------------- 113
Query: 457 KIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYL 636
++DV W+AME + G +K+IGVSNF+ QL L + + +KP++NQ+E +P+
Sbjct: 114 ---YNDV--FGAWRAMESAYRSGQLKAIGVSNFDIAQLTNLAEFSDIKPMLNQIEVNPFQ 168
Query: 637 NQKRLKEFCEARGVKITAYSP 699
K+ + GV++ A++P
Sbjct: 169 QNKKDITYFSQYGVQVEAWAP 189
>UniRef50_Q83N50 Cluster: 2,5-diketo-D-gluconic acid reductase; n=2;
Tropheryma whipplei|Rep: 2,5-diketo-D-gluconic acid
reductase - Tropheryma whipplei (strain Twist)
(Whipple's bacillus)
Length = 283
Score = 144 bits (348), Expect = 3e-33
Identities = 79/212 (37%), Positives = 123/212 (58%)
Frame = +1
Query: 64 MSSVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEA 243
++ VP V + + P GLGT++ P E + V+ AI++GYRHID A +Y NE+EVG A
Sbjct: 6 LTYVPSVLLGDGVSIPQFGLGTYELPPNEASSVVQSAIELGYRHIDTASLYANEREVGRA 65
Query: 244 ITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKE 423
I S + RE+ F+T+KLWN+ +P R A + +LD L++ Y+DLYLIHWP
Sbjct: 66 IAS----SGIKREEFFVTTKLWNS-DQPK-PREAFERSLDLLSLDYVDLYLIHWPCP--- 116
Query: 424 DGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKP 603
P++ Y++ W+ + L + G KS+GVSNF S+ ++++ + P
Sbjct: 117 -----PSEL----------YINVWEVLLELKESGRAKSVGVSNFLSEHIDKIKEAGFPLP 161
Query: 604 VVNQVECHPYLNQKRLKEFCEARGVKITAYSP 699
VNQ+E HP+L Q+ L C G++I ++ P
Sbjct: 162 SVNQIELHPWLQQRELVLSCRNDGIQIESWGP 193
>UniRef50_A7CUW0 Cluster: 2,5-didehydrogluconate reductase; n=6;
Bacteria|Rep: 2,5-didehydrogluconate reductase -
Opitutaceae bacterium TAV2
Length = 334
Score = 144 bits (348), Expect = 3e-33
Identities = 83/214 (38%), Positives = 116/214 (54%)
Frame = +1
Query: 64 MSSVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEA 243
M +P + ++ P LGLG W+ ++ A + GYR ID A +YGNE+ VG A
Sbjct: 56 MRMIPTLPLSDGTSIPQLGLGVWQMPDDGAGVPIQAAFNAGYRAIDTAPIYGNEEGVGRA 115
Query: 244 ITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKE 423
I + + R++L+IT+K+WN+ D A++E+L L ++Y+DLYLIHWP
Sbjct: 116 I----RASGLPRKELYITTKVWNSAQGYDSTLRAVRESLGRLQLEYVDLYLIHWPVP--- 168
Query: 424 DGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKP 603
KI YVDTWKA+ + +GL +SIGVSNF L+RL + P
Sbjct: 169 -----------KID----RYVDTWKALAKIKADGLARSIGVSNFTPVYLQRLFDETGIVP 213
Query: 604 VVNQVECHPYLNQKRLKEFCEARGVKITAYSPLG 705
VVNQVE HP L Q L+ F + A+SPLG
Sbjct: 214 VVNQVELHPRLQQHELRAFHAKHRIVTEAWSPLG 247
>UniRef50_A0JRJ6 Cluster: Aldo/keto reductase; n=2;
Micrococcineae|Rep: Aldo/keto reductase - Arthrobacter
sp. (strain FB24)
Length = 281
Score = 144 bits (348), Expect = 3e-33
Identities = 85/215 (39%), Positives = 115/215 (53%)
Frame = +1
Query: 61 KMSSVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGE 240
+ +++P + NN +K P LG G ++ P E + V+DA++ GYRHID A Y NE VG
Sbjct: 5 QQNTIPQLTLNNGVKIPQLGFGVFQVPPEETQRIVEDALEAGYRHIDTAAAYRNEAGVGA 64
Query: 241 AITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYK 420
AI++ + RED+FIT+KL N A Q + L V+++DLYLIHWP
Sbjct: 65 AISA----SGIPREDIFITTKLRN--GEQGNAHEAFQNSRKALGVEFVDLYLIHWPVP-- 116
Query: 421 EDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVK 600
S Y + WKAME L +++IGVSNF + L+ LL A V
Sbjct: 117 ----------------SQGLYTEAWKAMEKLYANSQIRAIGVSNFLGEHLDTLLPAADVV 160
Query: 601 PVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLG 705
P VNQVE HP Q+ L C G+ + AYSPLG
Sbjct: 161 PAVNQVEIHPTFQQQELAAKCRELGIAVEAYSPLG 195
>UniRef50_Q3E9M9 Cluster: Uncharacterized protein At5g01670.2; n=7;
Magnoliophyta|Rep: Uncharacterized protein At5g01670.2 -
Arabidopsis thaliana (Mouse-ear cress)
Length = 349
Score = 144 bits (348), Expect = 3e-33
Identities = 91/231 (39%), Positives = 123/231 (53%), Gaps = 27/231 (11%)
Frame = +1
Query: 103 KCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRE 282
K P +GLGTW+S V ++ GYRHID A+ YG+++EVG+ I + G+ R
Sbjct: 23 KIPAVGLGTWRSGSQAAHAVVTAIVEGGYRHIDTAWEYGDQREVGQGIKRAMHAGL-ERR 81
Query: 283 DLFIT----------------SKLWN-----------TFHRPDLVRGALQETLDNLNVQY 381
DLF+T S L N T P+ VR ALQ TL L ++Y
Sbjct: 82 DLFVTSKLWYTLILRKMINLSSPLMNVLVGTCLNKRCTELSPERVRPALQNTLKELQLEY 141
Query: 382 LDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNS 561
LDLYLIHWP +E S P ++G + D D W+ ME L K+ LV++IGV NF
Sbjct: 142 LDLYLIHWPIRLREGASKPP--KAGDVL--DFDMEGVWREMENLSKDSLVRNIGVCNFTV 197
Query: 562 KQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPD 714
+L +LL A + P V Q+E HP R+ EFC+ + +TAYSPLGS +
Sbjct: 198 TKLNKLLGFAELIPAVCQMEMHPGWRNDRILEFCKKNEIHVTAYSPLGSQE 248
>UniRef50_UPI00006CCCD7 Cluster: oxidoreductase, aldo/keto reductase
family protein; n=1; Tetrahymena thermophila SB210|Rep:
oxidoreductase, aldo/keto reductase family protein -
Tetrahymena thermophila SB210
Length = 323
Score = 143 bits (347), Expect = 3e-33
Identities = 82/219 (37%), Positives = 124/219 (56%), Gaps = 8/219 (3%)
Frame = +1
Query: 73 VPFVEFNNELKCPILGLGTW------KSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEV 234
+ +V+ NN K P+LGLGT + E+T + +A+D GYR+ D A Y NE E+
Sbjct: 12 IKYVQLNNGYKMPLLGLGTQPYDIVTRVTVEEMTTLLSNALDFGYRNFDTAKQYRNEVEI 71
Query: 235 GEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA 414
G+A + ++G RED+FIT+KL+ F ++ +Q +LD L Y+DLYLI W
Sbjct: 72 GQAFQNIFQQGKYKREDVFITTKLF-PFKIEKKIKEVVQNSLDQLQTSYIDLYLIQW--- 127
Query: 415 YKEDGSLFP--TDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQH 588
S P T+ G + + + W+ +E V+ G+++SIGV+NFN + + LL +
Sbjct: 128 -----SFTPVLTNFDGSVAVNHRPIHEVWRELEECVELGMIRSIGVANFNCQMVLDLLSY 182
Query: 589 ATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLG 705
A +KPVVNQ+E PYL Q L F + ++ A SPLG
Sbjct: 183 AKIKPVVNQIEVTPYLPQIDLINFLKRCKIETVAISPLG 221
>UniRef50_Q5TNP1 Cluster: ENSANGP00000029046; n=2; Culicidae|Rep:
ENSANGP00000029046 - Anopheles gambiae str. PEST
Length = 331
Score = 143 bits (347), Expect = 3e-33
Identities = 82/212 (38%), Positives = 118/212 (55%), Gaps = 4/212 (1%)
Frame = +1
Query: 85 EFNNELKCPILGLGTWKSKPGEVTQAVKD-AIDIGYRHIDCAYVYGNEKEVGEAITSKIK 261
+ N P+ G GT++ E+ V D A++ GYRHID A VY NE+ +G A+ + +
Sbjct: 35 KLNTGFDIPLAGFGTYQIHGQELIYQVLDYALEAGYRHIDTAVVYRNEEYIGTALKTLLP 94
Query: 262 EGVVTREDLFITSKLWNTFHRPD-LVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLF 438
+ + RED+FITSKL + + + V ++++L NL YLDLYLIHWP + G
Sbjct: 95 KYNLKREDIFITSKLISQSGKDEAFVEQMVRKSLANLQTDYLDLYLIHWPGVSGKCGRWK 154
Query: 439 PTDQSGKIQFSDVDY-VDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHAT-VKPVVN 612
+V Y +W A+ L +EG ++SIGVSN+ K L+ +L + P VN
Sbjct: 155 WLFGMQVTHPDNVKYRAASWNALSKLEREGCLRSIGVSNYTVKHLKEMLADCKGIVPAVN 214
Query: 613 QVECHPYLNQKRLKEFCEARGVKITAYSPLGS 708
QVE HPY Q L E+C G+ + AYS LGS
Sbjct: 215 QVEWHPYYYQPELLEYCRQHGIFLQAYSSLGS 246
>UniRef50_A7ALH6 Cluster: Putative uncharacterized protein; n=1;
Parabacteroides merdae ATCC 43184|Rep: Putative
uncharacterized protein - Parabacteroides merdae ATCC
43184
Length = 301
Score = 143 bits (346), Expect = 4e-33
Identities = 85/215 (39%), Positives = 125/215 (58%)
Frame = +1
Query: 61 KMSSVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGE 240
+M+ VP V+ NN ++ P LG+GT+ K + V AI +G+R ID A YGNEKEVGE
Sbjct: 25 EMNKVPTVKLNNGMEMPQLGVGTFLVKDN-AAERVCHAIKVGFRLIDTAQGYGNEKEVGE 83
Query: 241 AITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYK 420
I + G+ RE LFIT+K+ R VR +L ++L +L Y+DL LIHWP
Sbjct: 84 GIC---RSGIDRRE-LFITTKVNTMEMRGGTVRQSLDKSLADLGTDYIDLVLIHWP---- 135
Query: 421 EDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVK 600
G I+ +TW+ +E V +G ++SIGVSNFN L+ LL++A ++
Sbjct: 136 ---------VKGHIK-------ETWQILEEYVDKGKIRSIGVSNFNPHHLDELLEYARIR 179
Query: 601 PVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLG 705
PVVNQ+E PY+ Q + + +G+++ A+ PLG
Sbjct: 180 PVVNQIEIEPYMTQHDVVGYTFRKGIQVEAWGPLG 214
>UniRef50_P47137 Cluster: Probable oxidoreductase YJR096W; n=8;
Saccharomycetales|Rep: Probable oxidoreductase YJR096W -
Saccharomyces cerevisiae (Baker's yeast)
Length = 282
Score = 143 bits (346), Expect = 4e-33
Identities = 79/213 (37%), Positives = 129/213 (60%), Gaps = 5/213 (2%)
Frame = +1
Query: 79 FVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 258
F + +N K P + LGT+ + + V + + GYRH D A +YGNEKEVG+ I +
Sbjct: 5 FYKLSNGFKIPSIALGTYDIPRSQTAEIVYEGVKCGYRHFDTAVLYGNEKEVGDGIIKWL 64
Query: 259 KE--GVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLN-VQYLDLYLIHWPQAYKEDG 429
E G RE++F T+KLWN+ + + A+++ L+ ++ +QY+DL LIH P +G
Sbjct: 65 NEDPGNHKREEIFYTTKLWNSQNGYKRAKAAIRQCLNEVSGLQYIDLLLIHSPL----EG 120
Query: 430 SLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATV--KP 603
S K++ ++TW+AM+ V EGLVKSIGVSN+ K ++ LL + KP
Sbjct: 121 S--------KLR------LETWRAMQEAVDEGLVKSIGVSNYGKKHIDELLNWPELKHKP 166
Query: 604 VVNQVECHPYLNQKRLKEFCEARGVKITAYSPL 702
VVNQ+E P++ ++ L ++C+++G+ + A++PL
Sbjct: 167 VVNQIEISPWIMRQELADYCKSKGLVVEAFAPL 199
>UniRef50_A5ZYE6 Cluster: Putative uncharacterized protein; n=1;
Ruminococcus obeum ATCC 29174|Rep: Putative
uncharacterized protein - Ruminococcus obeum ATCC 29174
Length = 263
Score = 142 bits (345), Expect = 6e-33
Identities = 83/199 (41%), Positives = 113/199 (56%), Gaps = 1/199 (0%)
Frame = +1
Query: 109 PILGLGTWKSKPG-EVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 285
P+LGLG +K+ E A+ A+ GYR +D A Y NE+ VG I K GV R+D
Sbjct: 2 PLLGLGLYKTTDAVEAEDAIAAAVQNGYRLLDTASAYKNEEFVGCGIA---KCGV-PRKD 57
Query: 286 LFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQ 465
LFIT+K+WN R V GA Q +LD L + Y+DLYLIHWP G
Sbjct: 58 LFITTKIWNNAQRLGDVEGAFQRSLDRLGLDYIDLYLIHWP----VPGC----------- 102
Query: 466 FSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQK 645
+++TWK ME +++ G SIGVSNF + LE L + + + P VNQ+ECHP K
Sbjct: 103 -----FLNTWKDMEKILESGRALSIGVSNFEIRHLEELRRVSGIVPAVNQIECHPLCYPK 157
Query: 646 RLKEFCEARGVKITAYSPL 702
L E+C+A +++ AY+PL
Sbjct: 158 ELIEYCQANDIQVQAYAPL 176
>UniRef50_A5VK30 Cluster: 2,5-didehydrogluconate reductase; n=2;
Lactobacillus reuteri|Rep: 2,5-didehydrogluconate
reductase - Lactobacillus reuteri F275
Length = 300
Score = 142 bits (345), Expect = 6e-33
Identities = 78/212 (36%), Positives = 117/212 (55%), Gaps = 1/212 (0%)
Frame = +1
Query: 76 PFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSK 255
P ++ NN P LGLG WK+ E Q VK+AI Y ID A YGNE VG+ I
Sbjct: 11 PKIKLNNGHLIPQLGLGVWKASLAETQQMVKEAIMNDYVLIDTAKQYGNEAAVGQGIQDG 70
Query: 256 IKEGVVTREDLFITSKLWNTFHRP-DLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGS 432
K R+ +F+T+K++N D +R A+ E L L Y+DL L+HWP K
Sbjct: 71 FKATGRKRDSIFLTTKIFNGDQGDYDKLRQAVNEQLKKLQTNYVDLLLLHWPVNDK---- 126
Query: 433 LFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVN 612
Y ++W+A+E + K+G K+IGV NFN +++ LL HA +KP +N
Sbjct: 127 ----------------YNESWRALEDIYKDGQAKAIGVCNFNVERMTDLLDHAKIKPAIN 170
Query: 613 QVECHPYLNQKRLKEFCEARGVKITAYSPLGS 708
Q+E +P ++Q ++ +FC +++ A+SPLG+
Sbjct: 171 QIEFNPLIHQPKIVKFCRENDIQLEAWSPLGN 202
>UniRef50_A2UAH0 Cluster: Aldo/keto reductase; n=1; Bacillus
coagulans 36D1|Rep: Aldo/keto reductase - Bacillus
coagulans 36D1
Length = 273
Score = 141 bits (342), Expect = 1e-32
Identities = 76/206 (36%), Positives = 116/206 (56%), Gaps = 1/206 (0%)
Frame = +1
Query: 94 NELKCPILGLGTWKSKPGEVT-QAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 270
N + P +GLGTW+ GE T AV A+ GYRHID AY Y NE+ VG+A+ ++
Sbjct: 12 NGVAIPKIGLGTWQVPNGETTYHAVSFALKNGYRHIDTAYAYHNEESVGKAV----RDSG 67
Query: 271 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQ 450
+ R D+F+TSKL D ET+ N ++ LDLYLIH P + E G+ + +
Sbjct: 68 IDRRDIFVTSKLPAEIKSYDKALKTFDETMGNFGLEQLDLYLIHAPWPWSEKGADYTKEN 127
Query: 451 SGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHP 630
++ WKAME + + G ++IGVSNF+ L+ ++++A +KP+VNQ+
Sbjct: 128 -----------IEVWKAMEEIYESGRCRAIGVSNFSVSDLKAVMENAKIKPMVNQIRYFI 176
Query: 631 YLNQKRLKEFCEARGVKITAYSPLGS 708
Q+ + FC+ G+ + AYSPL +
Sbjct: 177 GHTQEDVTAFCQDNGILVEAYSPLAT 202
>UniRef50_Q8ZI40 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=74; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase
A - Yersinia pestis
Length = 277
Score = 141 bits (342), Expect = 1e-32
Identities = 80/214 (37%), Positives = 119/214 (55%), Gaps = 1/214 (0%)
Frame = +1
Query: 64 MSSVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEA 243
M+ P ++ + P LGLG W++ E AV A+++GYR ID A +Y NE+ VG+A
Sbjct: 1 MTMQPLIKLYDGRLMPQLGLGVWQASIQETELAVSKALEVGYRSIDTAAIYKNEEGVGKA 60
Query: 244 ITSKIKEGVVTREDLFITSKLWN-TFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYK 420
+K V R++LFIT+KLWN H P + AL+ +L L + Y+DLYLIHWP K
Sbjct: 61 ----LKAAAVARDELFITTKLWNDDQHNP---QQALETSLQKLQLDYVDLYLIHWPDP-K 112
Query: 421 EDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVK 600
+D YV W+ + L ++GL++SIGV NF+ L+RL+ +
Sbjct: 113 QD-----------------HYVSAWRELVTLKEQGLIRSIGVCNFHIPHLQRLIDETGIA 155
Query: 601 PVVNQVECHPYLNQKRLKEFCEARGVKITAYSPL 702
P VNQ+E HP L Q++L + + ++SPL
Sbjct: 156 PTVNQIELHPLLQQRQLHAWNATHHIATESWSPL 189
>UniRef50_Q235V6 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=2; Tetrahymena thermophila SB210|Rep:
Oxidoreductase, aldo/keto reductase family protein -
Tetrahymena thermophila SB210
Length = 332
Score = 141 bits (341), Expect = 2e-32
Identities = 79/207 (38%), Positives = 122/207 (58%), Gaps = 1/207 (0%)
Frame = +1
Query: 85 EFNNELKCPILGLGTWK-SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 261
+ NN P++GLGT+ + E+T ++ A+D GYRHID A Y NE +GE++ + K
Sbjct: 9 KLNNGQIMPLVGLGTYLLNSKEEMTNLLRTALDAGYRHIDTAVNYQNEAMIGESLKTIFK 68
Query: 262 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 441
EG +R+DLFI SK++ ++ + +++++L L + Y+DLY +H+P + +
Sbjct: 69 EGKYSRKDLFIVSKVFP--NKGINMLESVKKSLKELQLDYVDLYYLHFPLGFLSE----- 121
Query: 442 TDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVE 621
K +F + W +E + GL KSIGVSNFN L LL +A VKPV NQVE
Sbjct: 122 -----KEEFVHLPVHVAWAQLEEAHRLGLAKSIGVSNFNVMALADLLSYAKVKPVSNQVE 176
Query: 622 CHPYLNQKRLKEFCEARGVKITAYSPL 702
++ QK L +FC+ G+ +TAY+PL
Sbjct: 177 VSVFIQQKNLIKFCQRFGIHVTAYAPL 203
>UniRef50_Q2U219 Cluster: Aldo/keto reductase family proteins; n=6;
Pezizomycotina|Rep: Aldo/keto reductase family proteins
- Aspergillus oryzae
Length = 294
Score = 140 bits (340), Expect = 2e-32
Identities = 85/220 (38%), Positives = 120/220 (54%), Gaps = 9/220 (4%)
Frame = +1
Query: 70 SVPFVEFNNELKCPILGLGT---WKSKPG------EVTQAVKDAIDIGYRHIDCAYVYGN 222
+ P V+ N+ + PILG GT W + G E+ +A+K AI +GYRH+D A VYG
Sbjct: 8 NTPRVKLNDNVSIPILGYGTGTAWYKQAGDDSVNRELVEAIKTAIRLGYRHLDGAEVYGT 67
Query: 223 EKEVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIH 402
E E+G A IKE + RE+LF+T+K+ + A+ ++L L + Y+DLYLIH
Sbjct: 68 EAELGVA----IKESGIPREELFVTTKVITNIAD---IPSAIDQSLRKLQLNYVDLYLIH 120
Query: 403 WPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLL 582
P K DG L W AME + + G K+IGVSN++ LE L
Sbjct: 121 SPFFAKSDGEL----------------QQAWAAMEKVQQAGKAKAIGVSNYHQSHLEATL 164
Query: 583 QHATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPL 702
+ A + PV+NQ+E HPYL Q+ L F + +KI +Y PL
Sbjct: 165 KTAVIAPVINQIEHHPYLQQEELLRFQREKDIKIASYGPL 204
>UniRef50_O13848 Cluster: NADH/NADPH dependent indole-3-acetaldehyde
reductase AKR3C2; n=1; Schizosaccharomyces pombe|Rep:
NADH/NADPH dependent indole-3-acetaldehyde reductase
AKR3C2 - Schizosaccharomyces pombe (Fission yeast)
Length = 284
Score = 140 bits (340), Expect = 2e-32
Identities = 90/210 (42%), Positives = 120/210 (57%), Gaps = 8/210 (3%)
Frame = +1
Query: 97 ELKCPILGLGT--WKSKPGEVTQ----AVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 258
++ P G+GT +K + GE+ + +VK+A+ G+ HIDCA VYGNE+EVG A+
Sbjct: 9 KIPVPAYGVGTALFKKEKGEINRTIVDSVKNALAAGFIHIDCAEVYGNEEEVGVAL---- 64
Query: 259 KEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLF 438
KE V R LFITSK+ H D + AL E+L L YLDLYL+H P + E
Sbjct: 65 KEANVPRSKLFITSKV---MHNVDNIPEALNESLRKLGTDYLDLYLLHSPIPFYEK---- 117
Query: 439 PTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQV 618
KI S+ WKAME + GLV S+GVSNF LE LL+ +T+ P VNQ+
Sbjct: 118 ------KIPISE-----GWKAMETALGTGLVHSVGVSNFRIPDLEELLKTSTITPRVNQI 166
Query: 619 ECHP--YLNQKRLKEFCEARGVKITAYSPL 702
E HP Y K L EFC+++G+ + Y PL
Sbjct: 167 EFHPQVYKAAKPLVEFCQSKGIIVEGYGPL 196
>UniRef50_Q1DLF1 Cluster: Putative uncharacterized protein; n=1;
Coccidioides immitis|Rep: Putative uncharacterized
protein - Coccidioides immitis
Length = 324
Score = 140 bits (339), Expect = 3e-32
Identities = 84/214 (39%), Positives = 116/214 (54%), Gaps = 9/214 (4%)
Frame = +1
Query: 91 NNELKCPILGLGTWKSKP-----GEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSK 255
N ++ P GLGT++ P G V +V A+ IGYRHID A YG V I +
Sbjct: 11 NTSIRIPARGLGTFQVDPSLYPEGSVKDSVLHALKIGYRHIDAALAYG-WGSVERGIGAA 69
Query: 256 IKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSL 435
I+ V RED+F+ +KL N FH P+ V + +L NL + Y+ P AY + +
Sbjct: 70 IRASGVPREDVFVVTKLHNCFHAPEDVEVGMNMSLKNLGLGYV-------PYAYTKGENY 122
Query: 436 FPTDQSGKIQFSDVD----YVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKP 603
+ D++ + TWKAME LV +G K IGVSNF++ +L+RLL + P
Sbjct: 123 STVRKPDGKPVVDIELSRAFDTTWKAMENLVDQGKAKLIGVSNFSTPKLKRLLSVCRIFP 182
Query: 604 VVNQVECHPYLNQKRLKEFCEARGVKITAYSPLG 705
VVNQVE +PY QK+L FC + +TAY PLG
Sbjct: 183 VVNQVELNPYFPQKQLLRFCHEHEIHVTAYGPLG 216
>UniRef50_UPI0000DB6EE9 Cluster: PREDICTED: similar to C35D10.6;
n=2; Endopterygota|Rep: PREDICTED: similar to C35D10.6 -
Apis mellifera
Length = 292
Score = 140 bits (338), Expect = 4e-32
Identities = 76/203 (37%), Positives = 119/203 (58%), Gaps = 3/203 (1%)
Frame = +1
Query: 109 PILGLGTWKSKPGE-VTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 285
P++G GT+K + E V Q V +++++G+R ID A Y NE+++G A+ + + + + R D
Sbjct: 17 PLIGFGTYKIQGRELVYQVVDESLNVGFRSIDTAVGYRNEEDIGYALKNLLPKYNLQRSD 76
Query: 286 LFITSKLWNTFH-RPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKI 462
+FIT+KL + + P + +Q++L N Y+DLYLIHWP A + P +
Sbjct: 77 IFITTKLPPSVNGDPKGIEQCVQKSLKAFNTTYIDLYLIHWPGATR-----IPETSTNNP 131
Query: 463 QFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHA-TVKPVVNQVECHPYLN 639
TW + L K+G ++SIGVSNF K L+ LLQ+ + P VNQVE HP+
Sbjct: 132 SLR----AKTWNKLVDLKKQGFIRSIGVSNFTIKHLQELLQNCKDILPAVNQVELHPHYR 187
Query: 640 QKRLKEFCEARGVKITAYSPLGS 708
Q+ L ++C +G+ I AYS LG+
Sbjct: 188 QEELIKYCNEKGIHIQAYSSLGT 210
>UniRef50_Q28P63 Cluster: Aldo/keto reductase; n=4;
Rhodobacteraceae|Rep: Aldo/keto reductase - Jannaschia
sp. (strain CCS1)
Length = 276
Score = 140 bits (338), Expect = 4e-32
Identities = 74/215 (34%), Positives = 122/215 (56%)
Frame = +1
Query: 64 MSSVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEA 243
M+ P ++F++ + P +G G W+ + V+ AI+IGYR ID AY+Y NE +GE
Sbjct: 1 MTDRPVIKFHDGAQIPQVGFGIWQVPQDIAGETVRSAIEIGYRMIDGAYLYMNEAGLGEG 60
Query: 244 ITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKE 423
++ + R+++F+T+K+WN R +++ +L + V+ LDL LIHWP
Sbjct: 61 ----LRASGLPRDEVFVTTKVWNNEQGAAKARASVERSLKTIGVEQLDLVLIHWP----- 111
Query: 424 DGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKP 603
+ D+ Y++TWKA + + EGL++SIG SNFN+ LER++ P
Sbjct: 112 ------------VPSQDL-YLETWKAFQDMRDEGLMRSIGTSNFNADHLERIIAETGEAP 158
Query: 604 VVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGS 708
V+NQ+E +P L Q ++ +A GV A++PLG+
Sbjct: 159 VLNQIELNPMLQQPEMRAVHKAHGVVTQAWTPLGN 193
>UniRef50_A7BA05 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 292
Score = 139 bits (336), Expect = 7e-32
Identities = 75/198 (37%), Positives = 111/198 (56%)
Frame = +1
Query: 109 PILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 288
P+LG GT+K P + AV A+++GYRHID A +YGNE EVG A ++ + REDL
Sbjct: 28 PVLGFGTYKVAPEDTYDAVSRALEVGYRHIDTAQMYGNEAEVGAA----LEASGIAREDL 83
Query: 289 FITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQF 468
FIT+K+ N+ H PD +++ +L++L Y+DL L+HWP PT G
Sbjct: 84 FITTKVDNSNHEPDRAAASIRRSLEDLRTDYVDLLLVHWP---------LPTLYGG---- 130
Query: 469 SDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKR 648
D W A+E G ++IG+SN+ + +E + + ATV P V QVE HP+
Sbjct: 131 ---DVALPWPALEDAFNAGGARAIGLSNYEREHVEAVREVATVAPHVLQVESHPFFPNAD 187
Query: 649 LKEFCEARGVKITAYSPL 702
L+ + + G+ A+SPL
Sbjct: 188 LRAYAQGLGMVFEAWSPL 205
>UniRef50_Q17568 Cluster: Putative uncharacterized protein; n=1;
Caenorhabditis elegans|Rep: Putative uncharacterized
protein - Caenorhabditis elegans
Length = 287
Score = 139 bits (336), Expect = 7e-32
Identities = 71/209 (33%), Positives = 124/209 (59%), Gaps = 2/209 (0%)
Frame = +1
Query: 85 EFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKE 264
+ N + P L LGT+++K ++ AV +A+ +GYR D A Y NEK++G A+ + +
Sbjct: 3 KLKNGQEIPKLALGTYEAKGDQLFAAVDEALKVGYRSFDTAKYYENEKDLGLALKTLLPR 62
Query: 265 GVVTREDLFITSKL--WNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLF 438
+ ED+++TSK+ +++ + +L+R + E+L+ L+ +YLDL L+H+P+
Sbjct: 63 HNICSEDIYLTSKVFPYSSKNAAELIRKDVNESLELLDRKYLDLVLVHYPR--------- 113
Query: 439 PTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQV 618
P D + + + DTW A+E L EG ++SIGVSN+ +E + + T++P VNQ+
Sbjct: 114 PLDTEDLNENNKMYRKDTWIALEKLHAEGKIRSIGVSNYEPHHIEEMRSYITIEPQVNQI 173
Query: 619 ECHPYLNQKRLKEFCEARGVKITAYSPLG 705
E HP+ +K L+ +C + A+SPLG
Sbjct: 174 EYHPHFQRKVLRAYCNKNEILFQAFSPLG 202
>UniRef50_Q929C8 Cluster: Lin2349 protein; n=12; Listeria|Rep:
Lin2349 protein - Listeria innocua
Length = 294
Score = 138 bits (335), Expect = 1e-31
Identities = 86/199 (43%), Positives = 111/199 (55%), Gaps = 1/199 (0%)
Frame = +1
Query: 109 PILGLGTWKSKPGE-VTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 285
P +GLG ++ E + AV+ AI++GYR D A VY NE VG+AI + V RE+
Sbjct: 18 PYIGLGVFQVTEQEFIAGAVEKAIEVGYRLFDTAAVYNNEAIVGQAIL----DSAVPREE 73
Query: 286 LFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQ 465
LFI+SK+WN D A + TL NL + YLDLYLIHWP A K
Sbjct: 74 LFISSKVWNGDLGYDETLFAFERTLRNLKLDYLDLYLIHWPVAGK--------------- 118
Query: 466 FSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQK 645
Y D+W+AME L E L+KSIGV+NF L LL A KPV+NQVE HP L Q
Sbjct: 119 -----YRDSWRAMERLHDEKLIKSIGVANFKQHHLSDLLVAANEKPVLNQVETHPLLPQN 173
Query: 646 RLKEFCEARGVKITAYSPL 702
L+++ + + A+SPL
Sbjct: 174 DLRKYLAEQNIAHAAWSPL 192
>UniRef50_Q1RFP0 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=21; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase
A - Escherichia coli (strain UTI89 / UPEC)
Length = 294
Score = 138 bits (335), Expect = 1e-31
Identities = 84/214 (39%), Positives = 115/214 (53%), Gaps = 2/214 (0%)
Frame = +1
Query: 70 SVPFVEFNNELKCPILGLGTWKSKPGEVT-QAVKDAIDIGYRHIDCAYVYGNEKEVGEAI 246
+V F +N LK P++G G ++ +V Q+V +AI GYR ID A VYGNE VGEA+
Sbjct: 5 TVEFSVLSNNLKMPMMGFGVFQVTDKDVCKQSVLNAIRTGYRLIDTAAVYGNEDAVGEAV 64
Query: 247 TSKIKEGVVTREDLFITSKLW-NTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKE 423
I EG+ TRE+LFITSKLW D+ ++ +L ++Y DLYL+H QA +
Sbjct: 65 REAISEGLCTREELFITSKLWVQDMLNQDIAAAGIEASLKKSGLEYFDLYLLH--QAMR- 121
Query: 424 DGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKP 603
DY W+A+E +EG +K+IGVSNF L + VKP
Sbjct: 122 ------------------DYFSAWRALEDAYEEGKLKAIGVSNFYPHVLANFCETVRVKP 163
Query: 604 VVNQVECHPYLNQKRLKEFCEARGVKITAYSPLG 705
+VNQVE HPY Q + V+ A++PLG
Sbjct: 164 MVNQVELHPYFAQPEALATMKYYNVQPEAWAPLG 197
>UniRef50_Q5FKI1 Cluster: Reductase-dehydrogenase; n=1;
Lactobacillus acidophilus|Rep: Reductase-dehydrogenase -
Lactobacillus acidophilus
Length = 271
Score = 138 bits (333), Expect = 2e-31
Identities = 79/207 (38%), Positives = 111/207 (53%)
Frame = +1
Query: 82 VEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 261
V NN K P + LGTW EV + V+ A++IGYR D A YGNE VG+ I +
Sbjct: 7 VILNNGEKIPQIQLGTWLINNDEVNKVVRQAVNIGYRGFDTAKDYGNESGVGKGIWNSDI 66
Query: 262 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 441
E R D+F+T+KL + + A+ LD ++Y+DL LIH PQ + E
Sbjct: 67 E----RSDIFLTTKLPTAVKDYEGTKKAIDAALDKFGLEYIDLLLIHSPQPWIEVNRTND 122
Query: 442 TDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVE 621
G ++ W+AME VK G V+SIGVSNF + +E ++ + T+ P VNQ+E
Sbjct: 123 RHFKGNLE--------NWRAMEEAVKAGKVRSIGVSNFLQEDIENIVNNGTITPAVNQIE 174
Query: 622 CHPYLNQKRLKEFCEARGVKITAYSPL 702
H L ++C+ G+KI AYSPL
Sbjct: 175 VHIGKVPVELMDYCKKLGIKIEAYSPL 201
>UniRef50_Q17DN1 Cluster: Aldo-keto reductase; n=1; Aedes
aegypti|Rep: Aldo-keto reductase - Aedes aegypti
(Yellowfever mosquito)
Length = 284
Score = 138 bits (333), Expect = 2e-31
Identities = 61/95 (64%), Positives = 75/95 (78%)
Frame = +1
Query: 430 SLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVV 609
+L P D GK+QFSDVDY+DTWKAME L+K G VKSIGVSNFNS+Q+ RLL +KPV
Sbjct: 89 NLMPYDADGKLQFSDVDYIDTWKAMEKLLKTGKVKSIGVSNFNSEQITRLLAECEIKPVT 148
Query: 610 NQVECHPYLNQKRLKEFCEARGVKITAYSPLGSPD 714
NQVEC+P LNQ++L EFC+ + +TAYSPLG P+
Sbjct: 149 NQVECNPSLNQRKLTEFCKNLDITLTAYSPLGRPN 183
>UniRef50_Q5XJM7 Cluster: Zgc:101765; n=5; Eumetazoa|Rep: Zgc:101765
- Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 288
Score = 137 bits (332), Expect = 2e-31
Identities = 80/212 (37%), Positives = 116/212 (54%), Gaps = 1/212 (0%)
Frame = +1
Query: 76 PFVEFNNELKCPILGLGTWKSKPGEVT-QAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 252
P V NN+++ P+LGLGT++ + E T AV A+ GYR D A VY NE +G A+
Sbjct: 6 PSVLLNNDIQMPLLGLGTFRLQGQEDTYSAVDAALKAGYRAFDTAAVYRNEAHLGHALRC 65
Query: 253 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGS 432
+ + ++RED+FITSKL + R Q++L+ L + Y+DLYLIHWP
Sbjct: 66 LLPKHGLSREDVFITSKL-GPKDQGSKARNGCQKSLEQLGLGYIDLYLIHWPGTQG---- 120
Query: 433 LFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVN 612
P + + +W+ +E EG ++IGVSN+ + ++ LL+ V P V
Sbjct: 121 -LPVGDKRNPE----NRAQSWRVLEEFYSEGKFRAIGVSNYTVEHMQELLKSCKVPPAVL 175
Query: 613 QVECHPYLNQKRLKEFCEARGVKITAYSPLGS 708
QVE HP L Q L+ C+ RGV AYS LG+
Sbjct: 176 QVEFHPKLLQNDLRGLCKIRGVCFQAYSSLGT 207
>UniRef50_Q7VG53 Cluster: Aldo-keto reductase; n=28; Bacteria|Rep:
Aldo-keto reductase - Helicobacter hepaticus
Length = 292
Score = 137 bits (331), Expect = 3e-31
Identities = 81/209 (38%), Positives = 113/209 (54%), Gaps = 1/209 (0%)
Frame = +1
Query: 79 FVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAI-TSK 255
F NN K P LGLGTW+ V AV++A +GYRHID A YGNE+ VGEA+ SK
Sbjct: 14 FFTLNNGNKIPKLGLGTWRIDDNVVEAAVREAFKVGYRHIDTAQAYGNERGVGEAVRKSK 73
Query: 256 IKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSL 435
IK RE+LFITSK+ + ++ +L + + ++DL LIH PQ +
Sbjct: 74 IK-----REELFITSKIRAEYKDYKSASASIDTSLKTMKLDFIDLMLIHSPQPWNS---- 124
Query: 436 FPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQ 615
F K + V+ + A+E K G V+SIGVSNF K LE +L++ KP NQ
Sbjct: 125 FRKGDYFK------ENVEVYNALEDAQKAGKVRSIGVSNFLQKDLENILKNCKTKPAANQ 178
Query: 616 VECHPYLNQKRLKEFCEARGVKITAYSPL 702
+ CH L ++C+ + + AYSP+
Sbjct: 179 ILCHIGNTPFTLLDYCKKQNILAEAYSPI 207
>UniRef50_A5PDA8 Cluster: Putative oxidoreductase protein; n=1;
Erythrobacter sp. SD-21|Rep: Putative oxidoreductase
protein - Erythrobacter sp. SD-21
Length = 272
Score = 136 bits (330), Expect = 4e-31
Identities = 77/214 (35%), Positives = 114/214 (53%)
Frame = +1
Query: 64 MSSVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEA 243
M+ P + N+ + P LG GTW+ + + QAV AID+GY ID A +YGNEK VG
Sbjct: 1 MTDYPTLNLNDGRQIPQLGFGTWQMEEEDAPQAVSTAIDVGYWLIDTAAIYGNEKGVG-- 58
Query: 244 ITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKE 423
+GV D+F+ +K+WN D A ++ L+ L +++D+ LIHWP K+
Sbjct: 59 ------KGVGEWSDIFLQTKIWNDSQGYDRTLRAAEKCLERLGREHVDMLLIHWPCPEKD 112
Query: 424 DGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKP 603
+VDTWKA+ L G KSIGVSNF + L+R++ V P
Sbjct: 113 ------------------QFVDTWKALIELRDAGKAKSIGVSNFREEDLKRIIDETGVTP 154
Query: 604 VVNQVECHPYLNQKRLKEFCEARGVKITAYSPLG 705
+NQ+E HP Q+ +++ E G+ ++SPLG
Sbjct: 155 ALNQIELHPSFQQRDMRKVHEDLGIVTQSWSPLG 188
>UniRef50_Q6WGK4 Cluster: Aldose reductase; n=1; Pristionchus
pacificus|Rep: Aldose reductase - Pristionchus pacificus
Length = 293
Score = 136 bits (330), Expect = 4e-31
Identities = 71/204 (34%), Positives = 112/204 (54%), Gaps = 1/204 (0%)
Frame = +1
Query: 103 KCPILGLGTWKSKPGEV-TQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTR 279
+ P++G+GT++ + V T + +A +GYR ID A +Y NE +G + +++ + R
Sbjct: 15 RMPMIGVGTYQVQSQSVLTDTIDEAFRLGYRFIDTAQIYRNEAILGRILPDLLEKHSLKR 74
Query: 280 EDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGK 459
ED+FITSK+ ++ ++L +L Y+DL LIHWP S ++
Sbjct: 75 EDIFITSKVSPINQGKGKTSKSVLKSLTDLQTPYIDLVLIHWPGT-----SRLKSNHKDN 129
Query: 460 IQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLN 639
+F YV+ +E L+ EG ++SIGVSN+ K LE LL + P +NQ ECHP+
Sbjct: 130 AKFRAETYVE----LETLMDEGKIRSIGVSNYEIKHLETLLAECRILPAINQCECHPHFR 185
Query: 640 QKRLKEFCEARGVKITAYSPLGSP 711
L E+C+ +G+ AYS LG P
Sbjct: 186 NSELAEYCKEKGIHFQAYSSLGGP 209
>UniRef50_Q4JX70 Cluster: Putative oxidoreductase; n=1;
Corynebacterium jeikeium K411|Rep: Putative
oxidoreductase - Corynebacterium jeikeium (strain K411)
Length = 285
Score = 136 bits (329), Expect = 5e-31
Identities = 82/215 (38%), Positives = 114/215 (53%)
Frame = +1
Query: 61 KMSSVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGE 240
K ++VP +E N+ P LGLG W+ + +V+ AI+ GYRHID A +YGNE+ VG
Sbjct: 4 KNNAVPTLEMNDGKTTPQLGLGVWQLSDEDTYTSVRAAIETGYRHIDTAAIYGNEEAVGR 63
Query: 241 AITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYK 420
A+ +K G V RE+LFIT+KLWN + A E+ L + Y+DLYL+HWP
Sbjct: 64 AVADAVKAGDVQREELFITTKLWNADQA--CGKEAFAESQKKLGMDYVDLYLLHWP---- 117
Query: 421 EDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVK 600
P S +V + +M + + G SIGV NF + L+ L Q A
Sbjct: 118 -----CPQADS---------FVQAYDSMAEIQQSGGATSIGVCNFYPEALDALKQ-AGHT 162
Query: 601 PVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLG 705
P VNQ+E HP +Q + RG+ A+SPLG
Sbjct: 163 PAVNQIEIHPGFSQAEQRSDNRDRGIVTEAWSPLG 197
>UniRef50_Q043M4 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=2; Lactobacillus|Rep: Aldo/keto
reductase of diketogulonate reductase family -
Lactobacillus gasseri (strain ATCC 33323 / DSM 20243)
Length = 273
Score = 136 bits (329), Expect = 5e-31
Identities = 75/206 (36%), Positives = 114/206 (55%)
Frame = +1
Query: 91 NNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 270
NN++K PI G GT++ P + QAV A + GYR ID A Y NE++VGEA +K
Sbjct: 7 NNDVKIPIFGFGTYEISPDQTKQAVLSAFEEGYRLIDTAQYYQNEQQVGEA----VKASG 62
Query: 271 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQ 450
+ R+++FIT+K + + L E+L + + Y DL LIHWP +
Sbjct: 63 LNRDEVFITTKTMTDGYEDTKI--GLDESLRRIGLDYFDLVLIHWPMGHD---------- 110
Query: 451 SGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHP 630
+DTW A+E K G ++IG+SNFNS+Q L+ ++V+P+V+Q+E H
Sbjct: 111 -----------IDTWHALEAAYKAGKTRAIGISNFNSRQTLDLIHQSSVRPMVDQIETHL 159
Query: 631 YLNQKRLKEFCEARGVKITAYSPLGS 708
+L Q ++ EF E + +YSPLG+
Sbjct: 160 FLQQWKMHEFLEKENIVHESYSPLGN 185
>UniRef50_A3UJS6 Cluster: Oxidoreductase; n=3;
Alphaproteobacteria|Rep: Oxidoreductase - Oceanicaulis
alexandrii HTCC2633
Length = 275
Score = 136 bits (329), Expect = 5e-31
Identities = 76/203 (37%), Positives = 107/203 (52%)
Frame = +1
Query: 94 NELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVV 273
N P LG GTW+ + + + V A+ GYRHID A +YGNE VG+ K+ V
Sbjct: 8 NGADIPKLGFGTWQLEDEDAARGVATALKTGYRHIDTAQIYGNEAAVGDGW----KQSGV 63
Query: 274 TREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQS 453
RED F+T+K+W R ++ +++E+LD L Y+DL L+HWP
Sbjct: 64 KREDFFLTTKVWRDKFRDGDLQASVKESLDKLKTDYVDLLLLHWP--------------- 108
Query: 454 GKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPY 633
+V +T KAM + + G V+ IGVSNF L+ H+ V NQVE HPY
Sbjct: 109 ----VPEVPIAETMKAMNEVKEAGQVRHIGVSNFTVDLLDEARAHSGAPLVANQVEYHPY 164
Query: 634 LNQKRLKEFCEARGVKITAYSPL 702
L+Q + C A G+ +TAYSP+
Sbjct: 165 LDQNAVLTACRAAGMAMTAYSPI 187
>UniRef50_A7RRF6 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 275
Score = 136 bits (329), Expect = 5e-31
Identities = 79/200 (39%), Positives = 107/200 (53%)
Frame = +1
Query: 103 KCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRE 282
K P GLG + QAV A++ GYR ID A Y NEK VGEA+ +E V R
Sbjct: 14 KIPRFGLGLYDLDEKHTKQAVLWALENGYRMIDTAASYNNEKRVGEAL----RESAVPRS 69
Query: 283 DLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKI 462
++++ +K+++T H + A +L L V Y+DLYLIH+P
Sbjct: 70 EVYLVTKVYHTDHGYEKTMKAYDRSLSALGVDYVDLYLIHFPVP---------------- 113
Query: 463 QFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQ 642
V +W+AM L +GL +SIGVSNFN LE L +H+ + PVVNQ+E HPYL
Sbjct: 114 ----AGVVGSWEAMAELQGKGLTRSIGVSNFNIHHLEALQKHSVIPPVVNQIEVHPYLQM 169
Query: 643 KRLKEFCEARGVKITAYSPL 702
+ L +FC + I AYSPL
Sbjct: 170 EELVDFCRKHSIAIQAYSPL 189
>UniRef50_Q5BLA6 Cluster: Zgc:110782; n=2; Danio rerio|Rep:
Zgc:110782 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 287
Score = 136 bits (328), Expect = 7e-31
Identities = 81/212 (38%), Positives = 117/212 (55%), Gaps = 1/212 (0%)
Frame = +1
Query: 73 VPFVEFNNELKCPILGLGTWKSKPGE-VTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAIT 249
VP V + + P+LGLGT+K + E + Q+V A+ GYR D A VYGNE +G+ +
Sbjct: 3 VPSVRLMSGTQMPLLGLGTYKLQDHEQLKQSVSCALQAGYRAFDTAAVYGNEAHLGQVLK 62
Query: 250 SKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDG 429
+ + + RED+FI SKL + H G L+ +L+ L+ +Y+DLYLIHWP +G
Sbjct: 63 ELLPKYGLIREDVFIISKLAPSDHGLRAKEGCLR-SLEQLDCEYIDLYLIHWPGM---EG 118
Query: 430 SLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVV 609
L P D + S+ +W +E G K+IGVSN+ +K + LL V P V
Sbjct: 119 -LDPEDS----RHSEYR-AQSWATLEEFHASGQFKAIGVSNYTAKHIRELLASCRVPPAV 172
Query: 610 NQVECHPYLNQKRLKEFCEARGVKITAYSPLG 705
Q+EC P L Q+ L++ C G+ AYS LG
Sbjct: 173 LQIECQPKLIQRELRDLCMETGIHFQAYSSLG 204
>UniRef50_Q02198 Cluster: Morphine 6-dehydrogenase; n=5;
Bacteria|Rep: Morphine 6-dehydrogenase - Pseudomonas
putida
Length = 296
Score = 136 bits (328), Expect = 7e-31
Identities = 79/210 (37%), Positives = 111/210 (52%)
Frame = +1
Query: 76 PFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSK 255
P + NN +K P LGLG + + E A+ AI GYR ID A Y NE +VGE
Sbjct: 6 PLINLNNGVKMPALGLGVFAASAEETASAIASAISSGYRLIDTARSYNNEAQVGEG---- 61
Query: 256 IKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSL 435
I+ V R ++F+T+KL+N + + A E+L L + Y+DLYL+HWP
Sbjct: 62 IRNSGVDRAEMFVTTKLFNCDYGYERALRAFDESLGRLGLDYVDLYLLHWP--------- 112
Query: 436 FPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQ 615
D + IQ +WKA E ++ +G ++IGV NF QL+ L+ + V P VNQ
Sbjct: 113 -TKDWNATIQ--------SWKAAEKILGDGRARAIGVCNFLEDQLDELIAASDVVPAVNQ 163
Query: 616 VECHPYLNQKRLKEFCEARGVKITAYSPLG 705
+E HPY QK L A G+ A+SP+G
Sbjct: 164 IELHPYFAQKPLLAKNRALGIVTEAWSPIG 193
>UniRef50_Q8ET73 Cluster: 2,5-diketo-D-gluconate reductase; n=12;
Bacteria|Rep: 2,5-diketo-D-gluconate reductase -
Oceanobacillus iheyensis
Length = 280
Score = 135 bits (326), Expect = 1e-30
Identities = 77/213 (36%), Positives = 113/213 (53%)
Frame = +1
Query: 64 MSSVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEA 243
++ +P V ++ L P +G GT++ + QA+ +AID GYR ID AY Y NE VGEA
Sbjct: 2 VNQIPNVTLHDGLTIPKVGFGTYRLNGNDGVQAINNAIDHGYRLIDTAYNYENEGTVGEA 61
Query: 244 ITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKE 423
++ RE L ITSKL +H D +QE+L N+ Y DLYLIHWP
Sbjct: 62 ----VRRSSTPREQLLITSKLPGRYHHYDKAVTTIQESLYRANLDYYDLYLIHWPN---- 113
Query: 424 DGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKP 603
D+ YV+ W+A+ + G ++SIGV NF + LERL Q P
Sbjct: 114 -------------PIQDI-YVEAWQALIEAKRRGYIRSIGVCNFLPEHLERLKQETGELP 159
Query: 604 VVNQVECHPYLNQKRLKEFCEARGVKITAYSPL 702
+NQ+E HP+ NQ+ +++ + + ++SPL
Sbjct: 160 TINQIELHPFFNQEDQRKWHQEHQIATESWSPL 192
>UniRef50_A0JRJ3 Cluster: 2,5-didehydrogluconate reductase; n=3;
Actinobacteria (class)|Rep: 2,5-didehydrogluconate
reductase - Arthrobacter sp. (strain FB24)
Length = 276
Score = 135 bits (326), Expect = 1e-30
Identities = 80/215 (37%), Positives = 111/215 (51%)
Frame = +1
Query: 64 MSSVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEA 243
M+ P +E N+ + P +GLGTW +V AV +A++ GYRHID A YGNEK VG
Sbjct: 1 MALSPVIELNDGHRIPQIGLGTWPLDDHQVAAAVVNAVEGGYRHIDTAVKYGNEKGVGNG 60
Query: 244 ITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKE 423
I S + R +LFIT+KL F D L +L L + Y+DL LIHWP ++
Sbjct: 61 IRS----SGLDRSELFITTKLDGEFQGQDRAVAGLDGSLKRLGLDYVDLLLIHWPLPRRD 116
Query: 424 DGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKP 603
+++ TWK E L +G V+SIGVSNF LERL+ V P
Sbjct: 117 ------------------EFISTWKTFERLQADGKVRSIGVSNFKPAHLERLMAACDVVP 158
Query: 604 VVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGS 708
VNQ++ P + + + G+ +YSPLG+
Sbjct: 159 AVNQIQVSPAITRIVDIAYNRRHGIVTESYSPLGA 193
>UniRef50_Q5V6N9 Cluster: Alcohol dehydrogenase; n=2;
Halobacteriaceae|Rep: Alcohol dehydrogenase - Haloarcula
marismortui (Halobacterium marismortui)
Length = 667
Score = 135 bits (326), Expect = 1e-30
Identities = 72/222 (32%), Positives = 115/222 (51%), Gaps = 18/222 (8%)
Frame = +1
Query: 100 LKCPILGLGTWKSKPG---EVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 270
++ P +G G + + G + ++ A+D GYR +D A +YGNE +G + + G
Sbjct: 376 IRLPAIGFGCSRYRDGTYIDRADSIAAALDAGYRLLDSAELYGNEHRIGRILAAP---GA 432
Query: 271 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSL----- 435
R +FI K+W T HR + A + +LD L + D Y +HWP+A GSL
Sbjct: 433 PDRRRVFILGKVWRTNHRRKHMLTACRSSLDELGIDAFDCYALHWPEALAHRGSLTRLAE 492
Query: 436 ----------FPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQ 585
FP + G I+ V W+ +E L + G +++G+ N + QLE +++
Sbjct: 493 KSVARQEALTFPKNDRGDIETDSVSLQRAWENLEALHERGWTRTLGLCNVSQTQLETVIE 552
Query: 586 HATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSP 711
TV+P + QVE HPY Q L E+C RG+++ A+SPL +P
Sbjct: 553 TGTVRPALVQVERHPYQPQTDLIEYCHERGIRVVAHSPLSAP 594
>UniRef50_Q9A2X8 Cluster: Oxidoreductase, aldo/keto reductase
family; n=3; Caulobacter|Rep: Oxidoreductase, aldo/keto
reductase family - Caulobacter crescentus (Caulobacter
vibrioides)
Length = 279
Score = 133 bits (322), Expect = 4e-30
Identities = 80/211 (37%), Positives = 120/211 (56%), Gaps = 1/211 (0%)
Frame = +1
Query: 73 VPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 252
VP V + ++ P LG GTW+ + G V+ A++IGYRHID A +YGNE++VG A
Sbjct: 5 VPAVR-SGDVLMPALGFGTWQLENGTAVPLVEKALEIGYRHIDTAQIYGNERDVGAA--- 60
Query: 253 KIKEGVVTREDLFITSKLW-NTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDG 429
I+ V R+++F+T+K+W + F DL R A +++L+ L V +DL L+HWP+
Sbjct: 61 -IRNSGVKRDEIFLTTKVWIDQFADGDLQRSA-EKSLEKLGVDQVDLLLLHWPK------ 112
Query: 430 SLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVV 609
+V +T KA+ + +G ++IG+SNF S QLE + +
Sbjct: 113 -------------PEVPLAETLKALNAVRAKGWTRAIGLSNFPSAQLEEAAKLSEAPIAT 159
Query: 610 NQVECHPYLNQKRLKEFCEARGVKITAYSPL 702
+QVE HPYL+ K LK + GV ITA+SPL
Sbjct: 160 DQVEYHPYLSLKTLKAKADQLGVSITAWSPL 190
>UniRef50_Q11BF8 Cluster: Aldo/keto reductase; n=12; Bacteria|Rep:
Aldo/keto reductase - Mesorhizobium sp. (strain BNC1)
Length = 308
Score = 133 bits (322), Expect = 4e-30
Identities = 72/202 (35%), Positives = 114/202 (56%)
Frame = +1
Query: 100 LKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTR 279
++ P++GLG +++ P E T AV++A+ +GYRHID A YGNE+EVGE I+ + R
Sbjct: 27 VEMPMIGLGVFQTPPDETTAAVEEALRLGYRHIDTAAAYGNEREVGEG----IRRAGIAR 82
Query: 280 EDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGK 459
+++FI +K+W + + D A ++ L V +DL L+H P D +L
Sbjct: 83 DEVFIETKIWISDYGYDETLHAFDKSAGKLGVDQIDLLLLHQPLPSAFDRTL-------- 134
Query: 460 IQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLN 639
++A+E L+ +G V++IGVSNF + L RLL ++ P VNQ+E HPY
Sbjct: 135 ---------GAYRALEKLLADGKVRAIGVSNFMPEHLTRLLTETSIVPAVNQIEVHPYFQ 185
Query: 640 QKRLKEFCEARGVKITAYSPLG 705
Q+ L+ G+ A+SP+G
Sbjct: 186 QRALQRLHAEHGILTQAWSPIG 207
>UniRef50_Q4WUF7 Cluster: Aldo-keto reductase, putative; n=3;
Pezizomycotina|Rep: Aldo-keto reductase, putative -
Aspergillus fumigatus (Sartorya fumigata)
Length = 283
Score = 132 bits (320), Expect = 6e-30
Identities = 75/207 (36%), Positives = 121/207 (58%), Gaps = 3/207 (1%)
Frame = +1
Query: 91 NNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 270
N+++K P LG G ++S G+ Q+ A++ GYRHID A YGNEKEVGEA +++
Sbjct: 15 NSDVKIPRLGFGVYRSPTGQCVQSSLRALEAGYRHIDTAQFYGNEKEVGEA----LRKCG 70
Query: 271 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQ--YLDLYLIHWPQAYKEDGSLFPT 444
+ R D+F+T+K+ + P+ L E+++ + + Y+DL+LIH +
Sbjct: 71 IPRSDVFVTTKILSPAGSPEATYQKLLESVEKIGGRDGYVDLFLIH-------------S 117
Query: 445 DQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATV-KPVVNQVE 621
SG ++ W+A+E L++EG +SIGVSNF K +E + +A V P VNQ+E
Sbjct: 118 SSSGSAGRKEL-----WQALERLLEEGKTRSIGVSNFGVKHIEEMKAYAKVWPPHVNQIE 172
Query: 622 CHPYLNQKRLKEFCEARGVKITAYSPL 702
HP+ Q+ ++ +C+ G+ + AYSPL
Sbjct: 173 LHPWCQQRVIEAYCKRNGIVVEAYSPL 199
>UniRef50_Q88TV9 Cluster: Oxidoreductase; n=4; Lactobacillus|Rep:
Oxidoreductase - Lactobacillus plantarum
Length = 288
Score = 132 bits (318), Expect = 1e-29
Identities = 80/215 (37%), Positives = 114/215 (53%), Gaps = 1/215 (0%)
Frame = +1
Query: 64 MSSVPFVEFNNELKCPILGLGTWK-SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGE 240
M+ P + N+ P +G GT++ G QAVK+A+ IGYRHID A Y NE EVG+
Sbjct: 1 MTKTPTITLNDGRAIPAIGFGTFQIPDDGSTYQAVKEALVIGYRHIDTAVAYFNEDEVGQ 60
Query: 241 AITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYK 420
A IK+ + R+ +++TSKLW + D A+ +L L + Y+DLYLIH P
Sbjct: 61 A----IKDSGIPRDQIWVTSKLWLQDYGFDAASRAIDRSLTKLRLDYIDLYLIHQP---- 112
Query: 421 EDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVK 600
+ DV W+AME K G +KSIGVSN ++ +
Sbjct: 113 ---------------YGDVP--GAWQAMEAAQKAGKLKSIGVSNMTPTLWQKFVPQFETI 155
Query: 601 PVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLG 705
P VNQVE +PY Q+ L++ A+ VK+ A++PLG
Sbjct: 156 PAVNQVEFNPYFQQQPLRQLLAAQDVKLEAWAPLG 190
>UniRef50_Q568D7 Cluster: Zgc:110366; n=7; Euteleostomi|Rep:
Zgc:110366 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 289
Score = 131 bits (317), Expect = 1e-29
Identities = 82/212 (38%), Positives = 114/212 (53%), Gaps = 1/212 (0%)
Frame = +1
Query: 70 SVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAI-DIGYRHIDCAYVYGNEKEVGEAI 246
S P V +N L PILGLGT G +AV A+ + G RHID A YG E+ +G+A+
Sbjct: 12 SCPAVPLHNGLNIPILGLGT-SHYGGYSHEAVLYALQECGIRHIDTAKRYGCEEALGKAV 70
Query: 247 TSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKED 426
T E V RE+L++T+KLW + + A +++ L V YLDLYL+HWP
Sbjct: 71 T----ESGVQREELWVTTKLWPGDYGYQSTKQACRDSRARLGVDYLDLYLMHWPD----- 121
Query: 427 GSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPV 606
S+ P S +++ ++TW+A+E L EGL ++IGVSNF L L + P
Sbjct: 122 -SMVPGRSSQEVR------LETWRALEELYDEGLCRAIGVSNFLIPHLNELKDSGGIVPH 174
Query: 607 VNQVECHPYLNQKRLKEFCEARGVKITAYSPL 702
VNQVE HP+ +L E C + Y PL
Sbjct: 175 VNQVEFHPFQQPMKLVEHCRKENIVFEGYCPL 206
>UniRef50_A1UEC5 Cluster: 2,5-didehydrogluconate reductase; n=20;
Corynebacterineae|Rep: 2,5-didehydrogluconate reductase
- Mycobacterium sp. (strain KMS)
Length = 283
Score = 131 bits (317), Expect = 1e-29
Identities = 73/213 (34%), Positives = 112/213 (52%)
Frame = +1
Query: 67 SSVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAI 246
+ +P V N+ P+LGLG + E ++V A++ GYR ID A VYGNE VG A+
Sbjct: 9 AGIPSVSLNDGHSIPVLGLGVGELSEAEAERSVAAALEAGYRLIDTAAVYGNEAAVGRAV 68
Query: 247 TSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKED 426
+ + RE++++T+KL + A + +L+ L + Y+DLYLIHWP
Sbjct: 69 NAS----GIPREEIYVTTKLAVADQGFGTSQDAARASLERLGLDYVDLYLIHWPAG---- 120
Query: 427 GSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPV 606
GK Y+D+W + ++G+ +SIGV NFN++ L ++ + P
Sbjct: 121 -------DHGK-------YIDSWGGLMKAKQDGVARSIGVCNFNAEHLSNIIDLSFFTPA 166
Query: 607 VNQVECHPYLNQKRLKEFCEARGVKITAYSPLG 705
+NQ+E HP LNQ L+E G+ AY PLG
Sbjct: 167 INQIELHPLLNQAELREVNAGYGIVTEAYGPLG 199
>UniRef50_Q5UX52 Cluster: Oxidoreductase aldo/keto reductase family;
n=1; Haloarcula marismortui|Rep: Oxidoreductase
aldo/keto reductase family - Haloarcula marismortui
(Halobacterium marismortui)
Length = 274
Score = 131 bits (317), Expect = 1e-29
Identities = 76/198 (38%), Positives = 110/198 (55%)
Frame = +1
Query: 109 PILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 288
P LGLGTW+ + V+ A+ +GYRHID A YGNE++VG + + V RED+
Sbjct: 12 PALGLGTWQLTGQSCRETVETALGMGYRHIDTAQAYGNERQVGLGMDA----AAVDREDV 67
Query: 289 FITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQF 468
F+T+KL + VR + +E+L+ L YLDL LIHWP T +
Sbjct: 68 FLTTKLDGSNRDERSVRRSTRESLNKLGTDYLDLLLIHWPN----------TPWMASLS- 116
Query: 469 SDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKR 648
+T AM +V+EGLV+ IGVSNF+ L+R ++ +QV+ HPY +Q++
Sbjct: 117 ------ETLGAMNDVVEEGLVRHIGVSNFSPSLLDRARDISSAPIFTDQVQYHPYWDQRK 170
Query: 649 LKEFCEARGVKITAYSPL 702
L ++C V +TAYSPL
Sbjct: 171 LLDYCRIHDVLLTAYSPL 188
>UniRef50_Q890A0 Cluster: Oxidoreductase; n=6; Lactobacillales|Rep:
Oxidoreductase - Lactobacillus plantarum
Length = 282
Score = 131 bits (316), Expect = 2e-29
Identities = 74/206 (35%), Positives = 113/206 (54%), Gaps = 1/206 (0%)
Frame = +1
Query: 94 NELKCPILGLGTWKSKPGEVT-QAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 270
N + P + GTW+ GE T QAV+ A+ GYRHID A Y NE VG+AI ++
Sbjct: 12 NGVNIPKVAFGTWQIPGGEATYQAVRAALAAGYRHIDTALAYQNEASVGQAI----RDSG 67
Query: 271 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQ 450
+ RE +F+T+KL +L NL + Y+DLYL+H P +P Q
Sbjct: 68 IPREQIFVTTKLPAETKSYQGALNDFDRSLKNLGLDYVDLYLVHAP---------WPWGQ 118
Query: 451 SGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHP 630
G++ D +D W+AME + + G K+IGVSNF + L+ +L AT+ P+VNQ++ +
Sbjct: 119 VGRVY--DEANLDVWQAMEAIYQSGRAKAIGVSNFAVRDLKNILNQATIPPMVNQIQYYL 176
Query: 631 YLNQKRLKEFCEARGVKITAYSPLGS 708
+ ++ +F E + + AYSPL +
Sbjct: 177 GFTEPKITKFSEEHAMLVEAYSPLAT 202
>UniRef50_Q5FLI5 Cluster: Aldehyde reductase; n=2; Bacteria|Rep:
Aldehyde reductase - Lactobacillus acidophilus
Length = 278
Score = 131 bits (316), Expect = 2e-29
Identities = 76/208 (36%), Positives = 118/208 (56%), Gaps = 1/208 (0%)
Frame = +1
Query: 79 FVEFNNELKCPILGLGTWKSKP-GEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSK 255
FV NN +K P LG G ++ + Q V+D +++GYR +D A +YGNE+ VG+AI
Sbjct: 4 FVTLNNGIKMPRLGFGVYQIDDLAQAQQVVEDGLEVGYRLVDTAQIYGNEQAVGDAI--- 60
Query: 256 IKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSL 435
K V RED+FITSK+W + D A +++ L + Y+DLYLIH P Y
Sbjct: 61 -KHSNVPREDIFITSKIWVDDYGYDNTLKAFDDSMKKLQLDYIDLYLIHKP--YN----- 112
Query: 436 FPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQ 615
DY TW+A+E L +EG +++IGVS+F +++L L+ VKP VNQ
Sbjct: 113 --------------DYYGTWRALERLYQEGRIRAIGVSSFWNERLADLITFNDVKPAVNQ 158
Query: 616 VECHPYLNQKRLKEFCEARGVKITAYSP 699
+E + + + + +++ E GV+ A++P
Sbjct: 159 IETNVWNQEWKSQQYMEKEGVQPEAWAP 186
>UniRef50_O14088 Cluster: Xylose and arabinose reductase; n=1;
Schizosaccharomyces pombe|Rep: Xylose and arabinose
reductase - Schizosaccharomyces pombe (Fission yeast)
Length = 275
Score = 131 bits (316), Expect = 2e-29
Identities = 71/209 (33%), Positives = 116/209 (55%), Gaps = 1/209 (0%)
Frame = +1
Query: 79 FVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 258
FV+ NN LKCP G++ + +V A+ GYRHID A +Y NE + G AI +
Sbjct: 5 FVKLNNGLKCPQFAYGSYMVNRTKCFDSVYAALQCGYRHIDSAQMYHNEADCGRAILKFM 64
Query: 259 KEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLF 438
+E RED++ TSKL N ++ ++ + Y+DL+L+H P
Sbjct: 65 EETGTKREDIWFTSKL-NDLSGYKSTLSSIDASVKACGLGYIDLFLLHSPYG-------- 115
Query: 439 PTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQ-HATVKPVVNQ 615
D +++WKA+E V+EG +++IGVSNF ++ LL H + P VNQ
Sbjct: 116 -------------DRIESWKALEKGVEEGKLRAIGVSNFGPHHIQELLDSHPKIIPCVNQ 162
Query: 616 VECHPYLNQKRLKEFCEARGVKITAYSPL 702
+E HP+ +Q+++ ++CE++G+++ AY+PL
Sbjct: 163 IELHPFCSQQKVVDYCESKGIQLAAYAPL 191
>UniRef50_A5AD50 Cluster: Putative uncharacterized protein; n=3;
Magnoliophyta|Rep: Putative uncharacterized protein -
Vitis vinifera (Grape)
Length = 304
Score = 130 bits (314), Expect = 3e-29
Identities = 85/214 (39%), Positives = 111/214 (51%), Gaps = 1/214 (0%)
Frame = +1
Query: 73 VPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 252
+ F + N K P +GLGTW+S PG V QAV AI +GYRHIDCA VYGNE+E+G +
Sbjct: 5 IRFFQLNTGAKMPSVGLGTWQSDPGLVGQAVAIAIKVGYRHIDCAQVYGNEEEIGIVLKK 64
Query: 253 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGS 432
+GVV REDL+ITSKLW T G ++ + P A
Sbjct: 65 LFDDGVVKREDLWITSKLWCTESCTRRCTGGTKQNFEG-------------PAA-----R 106
Query: 433 LFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERL-LQHATVKPVV 609
L P + F ++ TWK + ++ G +S L RL L A V P V
Sbjct: 107 LHPLANEYEKGFC---WLQTWKTS----PNQIYQAHGEQWKHSMILARLELLVARVPPAV 159
Query: 610 NQVECHPYLNQKRLKEFCEARGVKITAYSPLGSP 711
QVECHP Q +L FC+++GV +T +SPLGSP
Sbjct: 160 IQVECHPSWQQSKLHAFCKSKGVHLTGFSPLGSP 193
>UniRef50_A6RMS0 Cluster: Putative uncharacterized protein; n=1;
Botryotinia fuckeliana B05.10|Rep: Putative
uncharacterized protein - Botryotinia fuckeliana B05.10
Length = 286
Score = 130 bits (314), Expect = 3e-29
Identities = 80/201 (39%), Positives = 114/201 (56%), Gaps = 2/201 (0%)
Frame = +1
Query: 109 PILGLGTWKSKPG--EVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRE 282
P +GLGT++ G +V VK AI GYRHID A YGNE+ +G+AI KE ++R+
Sbjct: 17 PAIGLGTFQGDDGNEKVKNIVKAAIQAGYRHIDGAAAYGNEEAIGDAI----KESGISRD 72
Query: 283 DLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKI 462
+L ++ W H P V AL +L+ L ++Y+ P AY + ++S K
Sbjct: 73 EL---AQPW---HEPKDVERALDLSLEALGLEYV-------PHAYLPGPNNVDYERSRK- 118
Query: 463 QFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQ 642
Y +TW+AME LV G K+IG+SNFN + +R+L+ A ++P VNQVE HPY Q
Sbjct: 119 ------YTETWQAMEKLVDSGKAKAIGLSNFNILKTKRILEIARIRPAVNQVEAHPYFPQ 172
Query: 643 KRLKEFCEARGVKITAYSPLG 705
L FCE + + A+ PLG
Sbjct: 173 HELLAFCEKEHIHLMAHQPLG 193
>UniRef50_P82125 Cluster: 1,5-anhydro-D-fructose reductase; n=1; Sus
scrofa|Rep: 1,5-anhydro-D-fructose reductase - Sus
scrofa (Pig)
Length = 206
Score = 106 bits (255), Expect(2) = 3e-29
Identities = 63/128 (49%), Positives = 73/128 (57%), Gaps = 1/128 (0%)
Frame = +1
Query: 103 KCPILGLGTWKSKPG-EVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTR 279
K P+LGLGTW++ PG EVT+AVK AID GYRH D AY+Y NE EVG I +KI EGVV R
Sbjct: 1 KIPVLGLGTWQAAPGGEVTEAVKVAIDTGYRHPDSAYLYHNEDEVGVGIQAKIDEGVVRR 60
Query: 280 EDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGK 459
EDLFI SK YLDL IHWP +K P D+SG
Sbjct: 61 EDLFIVSK----------------------KXXYLDLXNIHWPMQFKPGEVDLPVDRSGM 98
Query: 460 IQFSDVDY 483
I S+ D+
Sbjct: 99 IVASNTDF 106
Score = 44.8 bits (101), Expect(2) = 3e-29
Identities = 20/35 (57%), Positives = 24/35 (68%)
Frame = +1
Query: 601 PVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLG 705
PV NQ+E HPYL QK F ++R V +TAY PLG
Sbjct: 109 PVTNQIESHPYLTQK--ISFXQSRNVSVTAYRPLG 141
>UniRef50_A7D761 Cluster: Aldo/keto reductase; n=2;
Halobacteriaceae|Rep: Aldo/keto reductase - Halorubrum
lacusprofundi ATCC 49239
Length = 665
Score = 129 bits (312), Expect = 6e-29
Identities = 69/222 (31%), Positives = 111/222 (50%), Gaps = 18/222 (8%)
Frame = +1
Query: 100 LKCPILGLGTWKSKPGEVTQAVKD---AIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 270
++ P +G G + + GE V A+D GYR +D A +YGNE +GE + + G
Sbjct: 374 IRLPAVGFGCSRYRDGEYVDRVDSIATALDAGYRLLDSAELYGNEHRIGELLAAP---GA 430
Query: 271 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSL----- 435
RE +F+ K W T HR + + A + + L + D Y +HWP A + G L
Sbjct: 431 PDRERVFLLGKAWRTNHRREHLLAACAGSREELGIDAFDCYALHWPSALEHRGELNRLAE 490
Query: 436 ----------FPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQ 585
FP + G+ +DV W+ +E + + G +++G+ N + QLE +L+
Sbjct: 491 KPVERQETLTFPEGEDGEPATADVALATAWRNLEAVHERGWARTLGICNVSRAQLETVLE 550
Query: 586 HATVKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLGSP 711
+ P + QVE HPY + L E C RG+++ A+SPL +P
Sbjct: 551 TGEIDPALVQVERHPYRPRNGLVELCHGRGIRVVAHSPLSAP 592
>UniRef50_Q54NR2 Cluster: Aldo-keto reductase; n=3; Dictyostelium
discoideum AX4|Rep: Aldo-keto reductase - Dictyostelium
discoideum AX4
Length = 305
Score = 128 bits (310), Expect = 1e-28
Identities = 78/211 (36%), Positives = 114/211 (54%), Gaps = 8/211 (3%)
Frame = +1
Query: 94 NELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI--KEG 267
N +K P+LG+GT+K ++ +K ++ GYR ID A +Y NE+ +G+ + + +G
Sbjct: 23 NPIKMPMLGIGTFKLN--DIENIIKVGLENGYRRIDTASMYNNEERIGKVLNEMVTKNDG 80
Query: 268 V----VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSL 435
+ + REDLFITSK + A + +L L + YLD YLIHWP DGS
Sbjct: 81 LDGKKIKREDLFITSKCSFMEQGYENALKAFESSLKKLQLDYLDCYLIHWPGVKGLDGS- 139
Query: 436 FPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQ--HATVKPVV 609
D IQ + TW+A+E L ++ V+SIGVSN+ L LL + +KP +
Sbjct: 140 ---DSGNSIQRAQ-----TWRALEKLYQDKKVRSIGVSNYTINHLTELLSSPNLQIKPAI 191
Query: 610 NQVECHPYLNQKRLKEFCEARGVKITAYSPL 702
NQVE HP QK L EFC+ + + +Y L
Sbjct: 192 NQVEFHPLNFQKDLLEFCKNNKIILESYGSL 222
>UniRef50_Q6F7K7 Cluster: 2,5-diketo-D-gluconate reductase; n=20;
Bacteria|Rep: 2,5-diketo-D-gluconate reductase -
Acinetobacter sp. (strain ADP1)
Length = 297
Score = 128 bits (309), Expect = 1e-28
Identities = 75/212 (35%), Positives = 113/212 (53%)
Frame = +1
Query: 70 SVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAIT 249
++P + ++ P LG GT+ K + + A+ GYR +D A+ Y NE VG A+
Sbjct: 21 NIPDLILHDGHSIPALGFGTYTLKGQQGVDTMLRALGHGYRMLDSAFNYENEGAVGAAV- 79
Query: 250 SKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDG 429
++ + R+++FITSKL H D ++E+L + YLDLYLIHW
Sbjct: 80 ---RQSGLLRDEIFITSKLPGRHHAYDKAMETIEESLYRMQFDYLDLYLIHW-------- 128
Query: 430 SLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVV 609
P Q G Y++ W+A+ K+G ++SIGVSNF K +E L + V PV+
Sbjct: 129 ---PNPQQGL-------YIEAWQALIDAQKKGYIRSIGVSNFLPKHIETLRRETGVIPVI 178
Query: 610 NQVECHPYLNQKRLKEFCEARGVKITAYSPLG 705
NQVE HPY NQ + + E++ + A+SPLG
Sbjct: 179 NQVELHPYFNQAEQRAYDESQQIITMAWSPLG 210
>UniRef50_A2RMU6 Cluster: Oxidoreductase, aldo/keto reductase
family; n=3; Lactococcus lactis|Rep: Oxidoreductase,
aldo/keto reductase family - Lactococcus lactis subsp.
cremoris (strain MG1363)
Length = 281
Score = 128 bits (309), Expect = 1e-28
Identities = 83/203 (40%), Positives = 114/203 (56%), Gaps = 1/203 (0%)
Frame = +1
Query: 109 PILGLGTWKSKPGEVTQ-AVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 285
P GLG ++ GE T+ AVK+A+ +GYRHID A+ Y NE+ VG AI S G+ E
Sbjct: 14 PQFGLGVYQIPEGEATENAVKEALRLGYRHIDTAHAYQNERSVGRAIHSS---GIPISE- 69
Query: 286 LFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQ 465
++ITSKLW + + D A++ L+ LN++ +DL L+H Q G
Sbjct: 70 IWITSKLWPSDY--DDASQAIERMLELLNLKQIDLLLLH--------------QQVG--- 110
Query: 466 FSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQK 645
+Y W A+E VK G VKSIG+SNF+ ++L L A +KP QVE HPY QK
Sbjct: 111 ----NYRKAWIALENAVKSGKVKSIGISNFDGERLVDLFNFADIKPSALQVETHPYHQQK 166
Query: 646 RLKEFCEARGVKITAYSPLGSPD 714
L+EF + G KI ++ PLG D
Sbjct: 167 ELQEFLKPYGTKIESWYPLGHGD 189
>UniRef50_Q89JN4 Cluster: Oxidoreductase; n=8; Rhizobiales|Rep:
Oxidoreductase - Bradyrhizobium japonicum
Length = 272
Score = 128 bits (308), Expect = 2e-28
Identities = 72/208 (34%), Positives = 113/208 (54%)
Frame = +1
Query: 79 FVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 258
FVE N + P +GLGTW+ + V+ A+ +GYRHID A VY NE+EVG+ +
Sbjct: 3 FVEANGA-RIPAIGLGTWELSGRPCARVVEQALRLGYRHIDTAQVYDNEREVGDG----V 57
Query: 259 KEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLF 438
+ V R+D+F+T+K+W P+ + +++E+L L + +DL L+HWP
Sbjct: 58 RASGVRRDDVFLTTKVWTNHFAPNDLERSVKESLARLRLPSVDLLLLHWPN--------- 108
Query: 439 PTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQV 618
S V +T A+ + GL + IGVSNF +E+ + + V NQV
Sbjct: 109 ----------SHVPLAETLGALSHARQMGLTRHIGVSNFTVALIEQAVALSPEPLVCNQV 158
Query: 619 ECHPYLNQKRLKEFCEARGVKITAYSPL 702
E HPYL+Q +++ C+ G+ + AYSP+
Sbjct: 159 EFHPYLDQAKVRAACDQHGLALVAYSPI 186
>UniRef50_Q6CEJ0 Cluster: Yarrowia lipolytica chromosome B of strain
CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome B of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 302
Score = 128 bits (308), Expect = 2e-28
Identities = 82/223 (36%), Positives = 118/223 (52%), Gaps = 10/223 (4%)
Frame = +1
Query: 70 SVPFVEFNNELKCPILGLGT---WKSKPGE-----VTQAVKDAIDIGYRHIDCAYVYGNE 225
+VP V+ +N L+ P +G G+ WK PGE + AV AI+ G+ HID A YG E
Sbjct: 2 TVPKVKLSNGLEIPAIGFGSGTKWKRPPGEKEERELIDAVVSAINAGHLHIDTAEFYGTE 61
Query: 226 KEVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHW 405
K++GEA IKE V R+D+F+TSK D + ++ L L Y DL+LIH
Sbjct: 62 KQIGEA----IKESGVPRKDIFLTSKTLFGLLADDPIE-SISNQLKTLQTDYFDLFLIHV 116
Query: 406 PQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQ 585
P P D + D W +E L ++GL K+IGVSN + +LE +++
Sbjct: 117 P----------PNDD------INYDLAKAWGVLEQLYEKGLAKAIGVSNHSPAELETIIK 160
Query: 586 HATVKPVVNQVECHPYLNQKR--LKEFCEARGVKITAYSPLGS 708
A +KP VNQ+E HP L + + +FC+ + + YSPL S
Sbjct: 161 VAKIKPHVNQIEFHPLLQEPTPGIVDFCKQHDIVVEGYSPLAS 203
>UniRef50_Q1Q8W8 Cluster: Aldo/keto reductase; n=1; Psychrobacter
cryohalolentis K5|Rep: Aldo/keto reductase -
Psychrobacter cryohalolentis (strain K5)
Length = 282
Score = 127 bits (307), Expect = 2e-28
Identities = 75/204 (36%), Positives = 109/204 (53%), Gaps = 2/204 (0%)
Frame = +1
Query: 109 PILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 288
P+LGLGTW+S + V + +GY HID A YGNE EVG+ IK+ V R+
Sbjct: 17 PVLGLGTWQSTGQDCIDVVSQGLRMGYEHIDTAQAYGNEVEVGKG----IKQSGVARDKF 72
Query: 289 FITSKLW--NTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKI 462
F+T+K++ + P+ + A + +L+NL+ Y+DL L+HWP
Sbjct: 73 FLTTKIFPDDMKFEPEKLVAAAKRSLENLDTDYVDLLLLHWPD----------------- 115
Query: 463 QFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQ 642
V +T A+ L K+GL ++IGVSNFN + ++A V VVNQVE HP++ Q
Sbjct: 116 --DRVPLSETIPALCELQKQGLTRNIGVSNFNIANIIEAKRYADVPIVVNQVEFHPFIKQ 173
Query: 643 KRLKEFCEARGVKITAYSPLGSPD 714
K L+ F + + AYSPL D
Sbjct: 174 KTLQTFLNNHHILLEAYSPLARGD 197
>UniRef50_A6SI80 Cluster: Putative uncharacterized protein; n=1;
Botryotinia fuckeliana B05.10|Rep: Putative
uncharacterized protein - Botryotinia fuckeliana B05.10
Length = 253
Score = 127 bits (306), Expect = 3e-28
Identities = 78/213 (36%), Positives = 109/213 (51%), Gaps = 7/213 (3%)
Frame = +1
Query: 76 PFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSK 255
P ++ N+ + P +G G WK V +AI GYR D A
Sbjct: 4 PTLKLNSGHEMPQVGFGLWKVDNATCADTVYNAIKTGYRLFDGAC--------------- 48
Query: 256 IKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA--YKEDG 429
DLFI SKLWN+FH D V ++ L + + Y DL+++H+P A Y +
Sbjct: 49 ---------DLFIVSKLWNSFHDGDRVGPITRKQLADWGIDYFDLFIVHFPVALRYVDPA 99
Query: 430 SLFP-----TDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHAT 594
+P +D+ G +Q S +TW+AME LV EGL KSIGVSNF L LL++A
Sbjct: 100 VRYPPGWQYSDKEGDVQQSKASIQETWQAMEKLVDEGLAKSIGVSNFQGALLIDLLRYAR 159
Query: 595 VKPVVNQVECHPYLNQKRLKEFCEARGVKITAY 693
++P Q+E HPYL Q L + E+ G+K+TAY
Sbjct: 160 IRPATLQIEHHPYLVQNTLLKLAESEGIKVTAY 192
>UniRef50_Q927E1 Cluster: Lin2848 protein; n=13; Listeria|Rep:
Lin2848 protein - Listeria innocua
Length = 280
Score = 126 bits (305), Expect = 4e-28
Identities = 74/206 (35%), Positives = 113/206 (54%), Gaps = 1/206 (0%)
Frame = +1
Query: 91 NNELKCPILGLGTWK-SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEG 267
NN ++ P G G +K + + A++ A+D+GYR D A Y NEKE+G+ S
Sbjct: 12 NNGIEMPRHGFGVYKLTDEQRMRTALETAVDVGYRLFDTASFYHNEKELGDFFASS---- 67
Query: 268 VVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTD 447
+ R++ F+T+K+WNT D A +++ L + +DLYL+HWP K+D
Sbjct: 68 GLKRDEFFVTTKMWNTEQGYDETLRAFEKSQKKLQLDQVDLYLVHWP---KQD------- 117
Query: 448 QSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECH 627
+ +TW+A+E L EGLV++IGVSNF + L+RL A V PVV+Q+E H
Sbjct: 118 ----------TFFETWRAVEKLYDEGLVRAIGVSNFEAHHLDRLRTSANVLPVVDQLETH 167
Query: 628 PYLNQKRLKEFCEARGVKITAYSPLG 705
P+ + L + E + A+SPLG
Sbjct: 168 PHFPNQLLHRYLEELHIVHQAWSPLG 193
>UniRef50_Q7M4N1 Cluster: Dihydrodiol dehydrogenase DD2; n=2; Homo
sapiens|Rep: Dihydrodiol dehydrogenase DD2 - Homo
sapiens (Human)
Length = 188
Score = 77.0 bits (181), Expect(2) = 4e-28
Identities = 43/86 (50%), Positives = 54/86 (62%), Gaps = 2/86 (2%)
Frame = +1
Query: 457 KIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVK--PVVNQVECHP 630
+I F VD TW+AME KSIGVSNFN + LE +L +K PV NQVECHP
Sbjct: 55 EILFDTVDLCATWEAME--------KSIGVSNFNHRLLEMILNKPGLKYKPVCNQVECHP 106
Query: 631 YLNQKRLKEFCEARGVKITAYSPLGS 708
Y NQ++L +FC + + + AYS LGS
Sbjct: 107 YFNQRKLLDFC--KDIVLVAYSALGS 130
Score = 70.9 bits (166), Expect(2) = 4e-28
Identities = 34/68 (50%), Positives = 47/68 (69%)
Frame = +1
Query: 172 AIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQ 351
AI+ G+ HID A+VY NE++VG I +G V RED+F TSKLW+ HRP+LVR AL+
Sbjct: 2 AIEAGFHHIDSAHVYNNEEQVG------IADGSVKREDIFYTSKLWSNSHRPELVRPALE 55
Query: 352 ETLDNLNV 375
D +++
Sbjct: 56 ILFDTVDL 63
>UniRef50_Q7WSY4 Cluster: Putative aldo-keto reductase; n=1;
Propionibacterium freudenreichii subsp. shermanii|Rep:
Putative aldo-keto reductase - Propionibacterium
freudenreichii subsp. shermanii
Length = 280
Score = 126 bits (304), Expect = 5e-28
Identities = 74/216 (34%), Positives = 116/216 (53%)
Frame = +1
Query: 58 VKMSSVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVG 237
+ + P VE + + P+LG+GTW K E AV AI+ GYR +D A YGNE+ VG
Sbjct: 3 IPTTPTPTVELSGGTRMPMLGMGTWPLKGEECRAAVASAIEQGYRLVDTAEAYGNEEAVG 62
Query: 238 EAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAY 417
+A ++E R ++F+T+K +H V AL+ +L+ L + Y+DL+L+HWP
Sbjct: 63 KA----VREAGPDRAEIFVTTKFSKQWHSRKGVHEALEHSLERLGLDYVDLFLMHWPM-- 116
Query: 418 KEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATV 597
+GS YVD ++ M L ++GL K+IGVSNF L+ L+ +
Sbjct: 117 PGEGS----------------YVDAYRGMVELKEQGLAKAIGVSNFKVHHLDDLITEG-M 159
Query: 598 KPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLG 705
P VNQ++ P + +++F + + A+SPLG
Sbjct: 160 TPEVNQIQLDPSRPRLEVRDFLDNHDIVTEAWSPLG 195
>UniRef50_Q00XM4 Cluster: Aldo/keto reductase family proteins; n=2;
Ostreococcus|Rep: Aldo/keto reductase family proteins -
Ostreococcus tauri
Length = 336
Score = 126 bits (304), Expect = 5e-28
Identities = 74/199 (37%), Positives = 109/199 (54%)
Frame = +1
Query: 109 PILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 288
P+L GT++ + AV+DA+ G++H+D A VYGNE++VGEA+ + +E E +
Sbjct: 63 PMLAFGTYRLRGETCRDAVRDALRCGFQHVDTASVYGNERDVGEALRACHRE---VSERI 119
Query: 289 FITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQF 468
F+TSK+ + R + A ++ + DL L+HWP KE P + +
Sbjct: 120 FVTSKIAPSEMRSEEEAAAAIAGVNERLGRTPDLVLVHWPGRDKES----PDSERHR--- 172
Query: 469 SDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKR 648
D TW+A+E +K G ++IGVSN+ L LLQ VKP VNQ+E H Q
Sbjct: 173 -DARRW-TWRALENALKMGQCRAIGVSNYELSHLRELLQFCDVKPAVNQIELHARFPQTE 230
Query: 649 LKEFCEARGVKITAYSPLG 705
L+ FCE+ GV + YSPLG
Sbjct: 231 LRAFCESVGVHVVGYSPLG 249
>UniRef50_Q03X85 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=1; Leuconostoc mesenteroides subsp.
mesenteroides ATCC 8293|Rep: Aldo/keto reductase of
diketogulonate reductase family - Leuconostoc
mesenteroides subsp. mesenteroides (strain ATCC 8293
/NCDO 523)
Length = 288
Score = 125 bits (302), Expect = 1e-27
Identities = 77/213 (36%), Positives = 110/213 (51%), Gaps = 4/213 (1%)
Frame = +1
Query: 79 FVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 258
F NN + P LG G ++ E QAV DAI+ GYR ID A VYGNE E G+ + I
Sbjct: 3 FKTLNNGAQMPQLGFGVFQIPAEETKQAVVDAINAGYRSIDTARVYGNEAETGQGVNEAI 62
Query: 259 KEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLF 438
VV RE+LF+T+KLW + + +GA+ ++L L Y DL L+H P
Sbjct: 63 ANAVVAREELFLTTKLWLSEFSYEAAKGAIDDSLKKLGTDYADLILLHQPYG-------- 114
Query: 439 PTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNF-NSKQLERLLQHATVK---PV 606
D +KA+ +G VKSIG+SNF +K +E + T+ P
Sbjct: 115 -------------DVYGAYKALAEAQADGKVKSIGISNFYPAKFVEFIKVIKTMNLPVPQ 161
Query: 607 VNQVECHPYLNQKRLKEFCEARGVKITAYSPLG 705
++Q+E HPY +K ++ + GV+I A+ PLG
Sbjct: 162 IDQIEFHPYYQEKVARQLHDKYGVQIEAWGPLG 194
>UniRef50_Q6U5V3 Cluster: Putative uncharacterized protein; n=1;
Klebsiella pneumoniae|Rep: Putative uncharacterized
protein - Klebsiella pneumoniae
Length = 279
Score = 124 bits (300), Expect = 2e-27
Identities = 75/206 (36%), Positives = 105/206 (50%)
Frame = +1
Query: 91 NNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 270
N+ P G G W +V ++ A+ G+RH D A Y NE VG A+ +
Sbjct: 9 NDGYYMPRPGCGLWLIDNRDVDSLIRQALKAGFRHFDTAQAYFNEDGVGRAL----RYTE 64
Query: 271 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQ 450
V RE LFITSK+ + ETL+ L V+YL+L+LIHWP K
Sbjct: 65 VPREQLFITSKIRGRDMGYARTLVSFNETLERLGVEYLELFLIHWPIPAKNL-------- 116
Query: 451 SGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHP 630
YV+TW+A L GL++SIGVSNF + +ERL++ V P VNQ+E HP
Sbjct: 117 ----------YVETWEASIELEASGLIRSIGVSNFTCQHIERLIEDTGVVPAVNQLELHP 166
Query: 631 YLNQKRLKEFCEARGVKITAYSPLGS 708
+ Q ++++ G+ I +YSP GS
Sbjct: 167 HFQQCDVRDYHHEAGIAIQSYSPFGS 192
>UniRef50_Q15NA5 Cluster: Aldo/keto reductase; n=2;
Gammaproteobacteria|Rep: Aldo/keto reductase -
Pseudoalteromonas atlantica (strain T6c / BAA-1087)
Length = 273
Score = 124 bits (300), Expect = 2e-27
Identities = 72/200 (36%), Positives = 108/200 (54%), Gaps = 1/200 (0%)
Frame = +1
Query: 109 PILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 288
P G GT++ K + AV++A+D+GYRHID A Y NE EVG+AI++ ++R +L
Sbjct: 12 PTPGFGTYRLKGDDAKLAVENALDVGYRHIDTAQAYENEAEVGDAISA----SKISRGEL 67
Query: 289 FITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQF 468
F+T+K+W D ++Q +L LN Y+DL L+HWP S +
Sbjct: 68 FVTTKVWFDNLSADKFITSVQNSLTQLNTDYVDLLLVHWP--------------SPDNKV 113
Query: 469 SDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVV-NQVECHPYLNQK 645
S +Y+ KA + + GL + IGVSNF QL+ L ++ NQ+E HP K
Sbjct: 114 SMAEYLKELKACK---ERGLTRHIGVSNFTQSQLDEALSILGKDHILTNQIEVHPNFQNK 170
Query: 646 RLKEFCEARGVKITAYSPLG 705
L +C+ +++TAY PLG
Sbjct: 171 ELVAYCQRNNIQVTAYMPLG 190
>UniRef50_Q8G7K9 Cluster: Dehydrogenase or reductase protein; n=4;
Bifidobacterium|Rep: Dehydrogenase or reductase protein
- Bifidobacterium longum
Length = 289
Score = 123 bits (296), Expect = 5e-27
Identities = 70/215 (32%), Positives = 106/215 (49%)
Frame = +1
Query: 58 VKMSSVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVG 237
+ ++VP + + P +GLG + V V+ A++ GYRHID A Y NE VG
Sbjct: 6 INPANVPDIALKDGHSIPQVGLGVLRIDDEGVVPVVESALEAGYRHIDGAAGYNNEAGVG 65
Query: 238 EAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAY 417
A+ + RE L++T+KL ++ D A +L L + Y+D+Y+IHWP +
Sbjct: 66 RALAASGYNKGAKRETLWVTTKLRDSQQGYDSALKAFDNSLKLLQLDYVDMYMIHWPTPF 125
Query: 418 KEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATV 597
D DTWKA L EG+ +++GV NF L+RL +
Sbjct: 126 ------------------DWRSTDTWKAFVKLRDEGMARTLGVCNFMPADLKRLHEETGA 167
Query: 598 KPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPL 702
P VNQ+E HP Q+ + FC+ G+ + AYSP+
Sbjct: 168 WPAVNQIELHPTWQQREVVAFCKEHGIAVEAYSPM 202
>UniRef50_A6VNW9 Cluster: Aldo/keto reductase precursor; n=1;
Actinobacillus succinogenes 130Z|Rep: Aldo/keto
reductase precursor - Actinobacillus succinogenes 130Z
Length = 315
Score = 123 bits (296), Expect = 5e-27
Identities = 70/208 (33%), Positives = 112/208 (53%)
Frame = +1
Query: 82 VEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 261
V+ NN ++ PI+G+G W P + ++V +A+ GYR ID A +Y NE+ VG A ++
Sbjct: 45 VKLNNGIEMPIIGIGVWTLTPEQTEKSVGEALKAGYRLIDTARMYRNEQAVGRA----VR 100
Query: 262 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 441
+ + RE++FIT+K++ + + A+ E L L+ Y+DL L+H+P
Sbjct: 101 DSGIPREEIFITTKIYGSGDYAN-AEAAINERLRLLDTDYIDLLLLHYP----------- 148
Query: 442 TDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVE 621
D + WK ME VK G +++IG+SN++ K R++Q AT+ P V Q E
Sbjct: 149 ----------DQNDTKAWKVMEQFVKAGKIRAIGLSNYHRKTFNRIMQAATITPAVVQNE 198
Query: 622 CHPYLNQKRLKEFCEARGVKITAYSPLG 705
H Y K+ K F G ++ A+ PLG
Sbjct: 199 VHIYNQDKQTKAFLRNYGTQMEAWYPLG 226
>UniRef50_A7P424 Cluster: Chromosome chr1 scaffold_5, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr1 scaffold_5, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 247
Score = 123 bits (296), Expect = 5e-27
Identities = 89/228 (39%), Positives = 122/228 (53%), Gaps = 16/228 (7%)
Frame = +1
Query: 64 MSSVPFVEFNNELKC-PILGLGT--WKSKPGE-VTQAVKDAIDIGYRHIDCAYVYGNEKE 231
M S+P + + K P++G+ T + P E + ++ AI++GYRH DC Y +EK
Sbjct: 1 MISIPEMTLGSTGKAIPLVGMVTTVYPFAPSETMIDSILTAIELGYRHFDCVAAYLSEKP 60
Query: 232 VGEAITSKIKEGVV-TREDLFITSKLWNTFHRPDLVRGALQETL---------DNLNVQY 381
+GEAI +K G++ +R++LFITSKLW + D V ALQ TL NL + Y
Sbjct: 61 LGEAIKKAVKLGLIKSRDELFITSKLWCSDAHHDRVLPALQNTLKISSILSFSKNLQLDY 120
Query: 382 LDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNS 561
LDLYLIHW DG L +D WKAME K L K+IGVSNF+
Sbjct: 121 LDLYLIHW-----SDGHL------------PIDLGSVWKAMEDFQKLSLTKAIGVSNFSC 163
Query: 562 KQLERLLQHATVKPVVNQV-ECHPYLNQKRLKEFCEAR-GVKITAYSP 699
+LE LLQ A++ P VNQV E P L + + R V I+ ++P
Sbjct: 164 NKLEELLQTASILPAVNQVSENEPTLAAEEAQGVIYVRKRVSISRHTP 211
>UniRef50_Q9C1X5 Cluster: Xylose and arabinose reductase; n=1;
Schizosaccharomyces pombe|Rep: Xylose and arabinose
reductase - Schizosaccharomyces pombe (Fission yeast)
Length = 283
Score = 123 bits (296), Expect = 5e-27
Identities = 76/208 (36%), Positives = 109/208 (52%), Gaps = 1/208 (0%)
Frame = +1
Query: 82 VEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 261
V N + P +G G + K E V A+D GYRHID A VYGNE G+AI +
Sbjct: 11 VTLTNGMVIPRIGFGAFMLKYNECYGLVTQALDSGYRHIDTAAVYGNEDICGKAIVDWCE 70
Query: 262 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 441
+ V R D+F+TSKL N R A++ +L +L Y+DL+LI P K+
Sbjct: 71 KNNVKRTDIFLTSKLANCSDYYS-TRAAIRSSLHHLGT-YIDLFLIQSPAGGKK------ 122
Query: 442 TDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERL-LQHATVKPVVNQV 618
+ +WKAME V G ++S+GVSN+ K L+ L + P VNQ+
Sbjct: 123 ------------SRIASWKAMEEFVDSGDIRSVGVSNYGVKHLQELYASNPKFYPCVNQI 170
Query: 619 ECHPYLNQKRLKEFCEARGVKITAYSPL 702
E HP+L+Q + ++C++ + I AYSPL
Sbjct: 171 ELHPFLSQDDIVKYCQSHDIAIEAYSPL 198
>UniRef50_Q4WP69 Cluster: Aldehyde reductase, putative; n=1;
Aspergillus fumigatus|Rep: Aldehyde reductase, putative
- Aspergillus fumigatus (Sartorya fumigata)
Length = 350
Score = 123 bits (296), Expect = 5e-27
Identities = 72/164 (43%), Positives = 94/164 (57%), Gaps = 7/164 (4%)
Frame = +1
Query: 181 IGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETL 360
+GYRHID A V NE EVG K+ V RE +F+TSKLWNT H P V AL +T+
Sbjct: 72 VGYRHIDSAAVGLNEAEVGRGW----KKLGVPREGIFLTSKLWNTHHHPSHVEEALDKTV 127
Query: 361 DNLNVQYLDLYLI----HWPQAYKEDGSLFPTDQSGKIQFS--DVDYVDTWKAMEPLVKE 522
+L YLDLYL+ H Y+ P + G +F D+ DTW A E LV
Sbjct: 128 KDLQTNYLDLYLLYPLGHILHTYQRH---IPASRPGHKRFRLVDIPIGDTWAAREKLVNA 184
Query: 523 GLVKSIGVSN-FNSKQLERLLQHATVKPVVNQVECHPYLNQKRL 651
G ++S+GVSN F +++E LL A + P VNQ+E HPYL Q ++
Sbjct: 185 GKIRSLGVSNLFTIEKMEELLNTADIPPAVNQIEAHPYLLQPKI 228
>UniRef50_UPI00006CA3CB Cluster: oxidoreductase, aldo/keto reductase
family protein; n=3; Tetrahymena thermophila SB210|Rep:
oxidoreductase, aldo/keto reductase family protein -
Tetrahymena thermophila SB210
Length = 299
Score = 122 bits (295), Expect = 7e-27
Identities = 74/208 (35%), Positives = 111/208 (53%), Gaps = 1/208 (0%)
Frame = +1
Query: 82 VEFNNELKCPILGLGTWKSKP-GEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 258
+ +N K P GLG+ + + EVT ++ A+D+GYRHID A +Y NE+ +G A+ +
Sbjct: 10 ITLSNGQKMPAFGLGSSRVQSVEEVTNLIRKALDVGYRHIDTAQMYENEQFIGAALKTIF 69
Query: 259 KEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLF 438
EG RED+F+ +K + L ++E L L V Y+DL LIH P A
Sbjct: 70 GEGKYKREDIFLVTKQASIKGVSCLE--IMKEQLQKLQVDYVDLLLIHVPLAA------- 120
Query: 439 PTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQV 618
P+D + V + W E + GL K +GVSNFN + + LL + +KP+VNQ+
Sbjct: 121 PSDDYQQWNHKPVHQI--WAEFEEIHSLGLAKGLGVSNFNCQMIIDLLAYCKIKPLVNQI 178
Query: 619 ECHPYLNQKRLKEFCEARGVKITAYSPL 702
E H + QK L EF + + A+SP+
Sbjct: 179 ELHVFNQQKNLVEFLKKVNIYPVAFSPM 206
>UniRef50_Q09632 Cluster: Probable oxidoreductase ZK1290.5; n=2;
Caenorhabditis|Rep: Probable oxidoreductase ZK1290.5 -
Caenorhabditis elegans
Length = 321
Score = 122 bits (295), Expect = 7e-27
Identities = 78/211 (36%), Positives = 115/211 (54%), Gaps = 1/211 (0%)
Frame = +1
Query: 73 VPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAID-IGYRHIDCAYVYGNEKEVGEAIT 249
+P +N ++ P++GLGT S G AV +I GYR ID A YG EK++G A+
Sbjct: 2 IPTTVLSNNVEMPLIGLGTTHSG-GYYHDAVLHSIKKCGYRLIDTAKRYGVEKQLGIAV- 59
Query: 250 SKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDG 429
K V RE++F+++KLW D V A Q + + L YLD+Y+IH PQ D
Sbjct: 60 ---KNCSVPREEMFLSTKLWPV-DCGDEVYNAFQTSCEKLQTDYLDMYMIHMPQL--PDW 113
Query: 430 SLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVV 609
+ + K TW+ ME L ++ V+SIGVSN++ + L+ LL+ A++ P
Sbjct: 114 IVNQKETKEK----------TWRQMELLYEDEHVRSIGVSNYSIEDLDELLEFASILPHA 163
Query: 610 NQVECHPYLNQKRLKEFCEARGVKITAYSPL 702
NQVE HP+ +Q LK +C+ G+ Y PL
Sbjct: 164 NQVELHPWFHQADLKNYCDELGILTMGYCPL 194
>UniRef50_P70883 Cluster: AkrI; n=1; Butyrivibrio fibrisolvens|Rep:
AkrI - Butyrivibrio fibrisolvens
Length = 172
Score = 122 bits (294), Expect = 9e-27
Identities = 69/178 (38%), Positives = 97/178 (54%), Gaps = 1/178 (0%)
Frame = +1
Query: 82 VEFNNELKCPILGLGTWKSKP-GEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 258
++ NN P+ G GT+K K E +V+ A+ GYRHID A Y NEK V AI +
Sbjct: 8 IKLNNGTAIPMFGYGTYKIKDQNEAYNSVRLALKNGYRHIDTAAFYENEKFVANAIKDFM 67
Query: 259 KEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLF 438
+E RED+F+TSK W T D A ++T++ + + YLDLYL+HWP +Y D
Sbjct: 68 EESQTKREDIFVTSKAWKTELGYDKTLAAFEKTMNEMQMDYLDLYLVHWPASYAFDDDWE 127
Query: 439 PTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVN 612
T++ TWKAM + K G VK+IGVSNF + L+ ++ V P V+
Sbjct: 128 NTNR------------QTWKAMTEIYKSGRVKAIGVSNFLTHHLDTIID-MEVTPAVD 172
>UniRef50_A1CAM7 Cluster: Aldo-keto reductase, putative; n=9;
Dikarya|Rep: Aldo-keto reductase, putative - Aspergillus
clavatus
Length = 283
Score = 122 bits (294), Expect = 9e-27
Identities = 71/207 (34%), Positives = 115/207 (55%), Gaps = 3/207 (1%)
Frame = +1
Query: 91 NNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 270
N+ ++ P LG G ++S + Q+ A+ GYR+ID A Y NE+EVGEA+ +
Sbjct: 15 NSSVRIPRLGFGVYRSPTRQCVQSCLTALQAGYRNIDTAQFYANEQEVGEAL----RTSG 70
Query: 271 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQ--YLDLYLIHWPQAYKEDGSLFPT 444
+ R D+F+T+K+ + P+ L E+++ + + Y+DL+LIH +
Sbjct: 71 IPRSDVFVTTKILSPAGSPEATYKKLLESVEKIGGENGYVDLFLIH-------------S 117
Query: 445 DQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATV-KPVVNQVE 621
SG ++ W+A+E L++EG KSIGVSNF K +E + +A V P VNQ+E
Sbjct: 118 SSSGSAGRKEL-----WQALEKLLEEGKTKSIGVSNFGVKHIEEMKAYAKVWPPHVNQIE 172
Query: 622 CHPYLNQKRLKEFCEARGVKITAYSPL 702
HP+ Q+ + +C+ G+ + AYSPL
Sbjct: 173 LHPWCQQRVIDAYCKRNGIVVEAYSPL 199
>UniRef50_P91997 Cluster: Putative uncharacterized protein; n=4;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 297
Score = 122 bits (293), Expect = 1e-26
Identities = 67/207 (32%), Positives = 112/207 (54%), Gaps = 1/207 (0%)
Frame = +1
Query: 85 EFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKE 264
+ N+ P +G GT+K V A+ A+ GYR D A Y NEKE+GEA+ + +
Sbjct: 14 KLNSGYNIPFVGFGTYKVTGENVPPAIDAALTAGYRMFDTAKYYLNEKELGEALKILLPK 73
Query: 265 GVVTREDLFITSKLW-NTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 441
++R D+F+TSK + + + + RG ++E+L +L Y+D+YL+H+P+ D
Sbjct: 74 HGLSRSDVFLTSKFFPESKNCREACRGFVEESLQSLQTDYIDMYLVHYPKPNDSD----- 128
Query: 442 TDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVE 621
D ++ + Y + +E G V+SIGVSN+ LE L +A V P NQ+E
Sbjct: 129 NDDVNNAEYRKIAY----EVLEEAKAAGKVRSIGVSNYEIVHLEELKTYAKVPPCANQLE 184
Query: 622 CHPYLNQKRLKEFCEARGVKITAYSPL 702
HP+ + L+++C+ + + A+S L
Sbjct: 185 YHPHFARIPLQKYCKEKNIFFQAFSSL 211
>UniRef50_Q5V398 Cluster: Oxidoreductase aldo/keto reductase family;
n=1; Haloarcula marismortui|Rep: Oxidoreductase
aldo/keto reductase family - Haloarcula marismortui
(Halobacterium marismortui)
Length = 302
Score = 120 bits (290), Expect = 3e-26
Identities = 75/208 (36%), Positives = 107/208 (51%), Gaps = 2/208 (0%)
Frame = +1
Query: 85 EFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKE 264
E N P LG GT+++ + AVK+A+D GY HID A Y NE VG A I++
Sbjct: 13 EQNGTTTVPTLGFGTYRTGGYKCYNAVKNALDCGYTHIDTAMAYENEAAVGRA----IEQ 68
Query: 265 GVVTREDLFITSKLWNTFHRPDLVR--GALQETLDNLNVQYLDLYLIHWPQAYKEDGSLF 438
V RED+F+T+K+ + R A + L+ L +YLDL L+HW
Sbjct: 69 SSVDREDIFLTTKIKGYPEMVEYERLIEAAKGCLERLGTEYLDLLLVHWWNPL------- 121
Query: 439 PTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQV 618
D +T+ A+ LV +GLV IGVSNF+ K+L++ ++ + NQ+
Sbjct: 122 ------------ADMEETFNALNTLVDDGLVGQIGVSNFSIKELKQAMRLSDAPIATNQI 169
Query: 619 ECHPYLNQKRLKEFCEARGVKITAYSPL 702
E HPY + L FC+ V +TAYSPL
Sbjct: 170 EYHPYWGDEELVRFCQDNDVTVTAYSPL 197
>UniRef50_Q572D2 Cluster: Aldo-keto reductase, putative; n=1;
Phytophthora infestans|Rep: Aldo-keto reductase,
putative - Phytophthora infestans (Potato late blight
fungus)
Length = 255
Score = 120 bits (288), Expect = 5e-26
Identities = 70/202 (34%), Positives = 113/202 (55%), Gaps = 1/202 (0%)
Frame = +1
Query: 70 SVPFVEFNNELKCPILGLGTWKSKPG-EVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAI 246
+VP + + P++GLG ++S+PG E A+ ++ +GYRHID A +YGNE++VG A
Sbjct: 4 NVPTKILPSGARIPMIGLGVYQSEPGPETYNAILTSLKLGYRHIDTAEIYGNEEDVGRA- 62
Query: 247 TSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKED 426
+++ + RE++F+T+KL+ T A + + D L + Y+ LYL+H P KE
Sbjct: 63 ---VRDSGIPREEIFVTTKLFTTNWGYSKALAAGKASNDRLGIVYIYLYLLHAPGPPKE- 118
Query: 427 GSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPV 606
DTW+A+E L ++ ++ IGVSNFN L L + A +KP
Sbjct: 119 ------------------RADTWRAVEDLREQETLRDIGVSNFNETLLATLRKTAHIKPA 160
Query: 607 VNQVECHPYLNQKRLKEFCEAR 672
VNQVE HP++ ++ L + + R
Sbjct: 161 VNQVELHPWMMRQSLVNYQDGR 182
>UniRef50_P15339 Cluster: 2,5-diketo-D-gluconic acid reductase B;
n=6; Actinomycetales|Rep: 2,5-diketo-D-gluconic acid
reductase B - Corynebacterium sp. (strain SHS752001)
Length = 277
Score = 120 bits (288), Expect = 5e-26
Identities = 74/213 (34%), Positives = 108/213 (50%)
Frame = +1
Query: 64 MSSVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEA 243
M ++P + N+ GLGT+ + E A+ AID GYR +D A Y NE EVG A
Sbjct: 1 MPNIPTISLNDGRPFAEPGLGTYNLRGDEGVAAMVAAIDSGYRLLDTAVNYENESEVGRA 60
Query: 244 ITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKE 423
+ + V R++L + SK+ H +++ +LD L + +DL LIHWP
Sbjct: 61 V----RASSVDRDELIVASKIPGRQHGRAEAVDSIRGSLDRLGLDVIDLQLIHWPNP--- 113
Query: 424 DGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKP 603
G+ ++DTW+ M + GLV+SIGVSNF L+ L+ V P
Sbjct: 114 --------SVGR-------WLDTWRGMIDAREAGLVRSIGVSNFTEPMLKTLIDETGVTP 158
Query: 604 VVNQVECHPYLNQKRLKEFCEARGVKITAYSPL 702
VNQVE HPY Q L+ F + G++ ++SPL
Sbjct: 159 AVNQVELHPYFPQAALRAFHDEHGIRTESWSPL 191
>UniRef50_Q03U37 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=5; Lactobacillus|Rep: Aldo/keto
reductase of diketogulonate reductase family -
Lactobacillus brevis (strain ATCC 367 / JCM 1170)
Length = 282
Score = 119 bits (287), Expect = 6e-26
Identities = 77/200 (38%), Positives = 106/200 (53%), Gaps = 1/200 (0%)
Frame = +1
Query: 109 PILGLGTWK-SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 285
P++G GT+ + + A++ A D GYR D A +Y NE +G AI ++ + RE
Sbjct: 19 PVMGFGTYLLNDQPTMNTAIQTAWDAGYRMFDTAMLYRNEDILGPAI----QQLGLPREG 74
Query: 286 LFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQ 465
LF+TSK+ D A++ +L L YLDL LIHWP +E
Sbjct: 75 LFLTSKVAEIVQGYDQTMKAVEGSLKRLQTDYLDLLLIHWP--VREH------------- 119
Query: 466 FSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQK 645
+ DTW+A+E L +G VKSIGVSN+ LE L A PVVNQVE HPYLNQ+
Sbjct: 120 -----FFDTWRALEQLKADGQVKSIGVSNYTIAHLELLATKAKEMPVVNQVEYHPYLNQQ 174
Query: 646 RLKEFCEARGVKITAYSPLG 705
L ++ + + A+SPLG
Sbjct: 175 ALADYDQEHDIVTEAWSPLG 194
>UniRef50_A7BES9 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 282
Score = 119 bits (287), Expect = 6e-26
Identities = 70/208 (33%), Positives = 107/208 (51%)
Frame = +1
Query: 82 VEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 261
+ NN + P +GLGT+ +P + AV A+D Y ID A VY NE+ VG + + K
Sbjct: 4 ITLNNGITIPQVGLGTYLLEPDDAQSAVTYALDNDYTLIDTANVYVNERAVGRGMRASSK 63
Query: 262 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 441
R+++F+ +KLW +F A++ETL+ L Y+DL ++H P
Sbjct: 64 ----ARDEIFLETKLWPSFFER---ASAVEETLERLGTDYIDLMILHQPAG--------- 107
Query: 442 TDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVE 621
D V ++ +E KEG +++IG+SNF+ Q +R+L V P +NQVE
Sbjct: 108 ------------DTVAGYRILEKAHKEGKIRAIGLSNFDVAQTQRILDECEVVPTINQVE 155
Query: 622 CHPYLNQKRLKEFCEARGVKITAYSPLG 705
CHPY Q LK + + + A+ PLG
Sbjct: 156 CHPYFPQTELKALLKDHNITLQAWYPLG 183
>UniRef50_Q8EUH6 Cluster: Oxidoreductase; n=1; Mycoplasma
penetrans|Rep: Oxidoreductase - Mycoplasma penetrans
Length = 285
Score = 119 bits (286), Expect = 8e-26
Identities = 73/210 (34%), Positives = 110/210 (52%), Gaps = 1/210 (0%)
Frame = +1
Query: 79 FVEFNNELKCPILGLGTWKSKPGEVTQAVKDAID-IGYRHIDCAYVYGNEKEVGEAITSK 255
+++ N L PI+GLG +K++ + AID GYR ID A VY NE+ VG AI
Sbjct: 3 YIKLANGLHMPIIGLGVYKAEGENCENTIIKAIDDYGYRMIDTAQVYFNEEFVGNAI--- 59
Query: 256 IKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSL 435
K+ + RED+FIT+K+W + + + ++ ++L L Y+DL L+H P
Sbjct: 60 -KQTKIKREDIFITTKVWISNYGYNNTMYSISKSLKKLQTNYIDLVLLHQPFG------- 111
Query: 436 FPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQ 615
DY WKA+E L K+G+VK+IGVSNF + +L H VKPV+NQ
Sbjct: 112 --------------DYYSAWKALEVLYKKGIVKAIGVSNFEADRLVDFCLHVDVKPVINQ 157
Query: 616 VECHPYLNQKRLKEFCEARGVKITAYSPLG 705
+E HP + + GV + +++ G
Sbjct: 158 IELHPLRQRIEDLHWNNKYGVAVESWASFG 187
>UniRef50_A3WP89 Cluster: Aldo/keto reductase; n=1; Idiomarina
baltica OS145|Rep: Aldo/keto reductase - Idiomarina
baltica OS145
Length = 263
Score = 119 bits (286), Expect = 8e-26
Identities = 71/199 (35%), Positives = 104/199 (52%), Gaps = 1/199 (0%)
Frame = +1
Query: 109 PILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 288
P G+GT++ + E+T V AID+GY HID A YGNE +VG+A+ T +D+
Sbjct: 3 PQFGMGTFRLEGQELTDLVSAAIDMGYEHIDTAQFYGNEADVGKALAQH------TNKDV 56
Query: 289 FITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQF 468
F+T+K+W V +LQ + D L +DL LIHWP P D
Sbjct: 57 FVTTKVWYEKLAYQDVLDSLQVSRDKLQRDTIDLALIHWPS---------PND------- 100
Query: 469 SDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVV-NQVECHPYLNQK 645
+V +T A++ ++GL+K +GVSNF L R H ++ NQ+E HP+
Sbjct: 101 -EVPVEETLDALQKAQQDGLIKHLGVSNFTIDLLNRAAAHVGKDEILTNQIEVHPFFQNH 159
Query: 646 RLKEFCEARGVKITAYSPL 702
+ + C+ GVK+TAY PL
Sbjct: 160 AITDACKQMGVKVTAYLPL 178
>UniRef50_Q9P734 Cluster: Related to 2, 5-diketo-D-gluconic acid
reductase; n=5; Pezizomycotina|Rep: Related to 2,
5-diketo-D-gluconic acid reductase - Neurospora crassa
Length = 289
Score = 119 bits (286), Expect = 8e-26
Identities = 73/212 (34%), Positives = 112/212 (52%), Gaps = 5/212 (2%)
Frame = +1
Query: 82 VEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 261
V+ +N L P + LG + E T+AV+ A+ GYR D A Y NE+E G+AI S +
Sbjct: 13 VKLSNGLSIPQIQLGLYMMSGPETTRAVRWALGAGYRGFDSAQWYYNEREAGQAILSFLS 72
Query: 262 E----GVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDG 429
+TR+D+ TSKL + D VR ++ +++ + Y+DL+L+H P +E
Sbjct: 73 SPENTAGLTRKDVHFTSKLRDNSTNYDAVRASISKSVKASGLGYIDLFLLHSPLGGREAR 132
Query: 430 SLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHA-TVKPV 606
+ +WKA+E V G VK GVSN+ K L+ ++ +KP+
Sbjct: 133 ------------------LTSWKAVEDAVLAGEVKMAGVSNYGVKHLDEVMSAPFKIKPL 174
Query: 607 VNQVECHPYLNQKRLKEFCEARGVKITAYSPL 702
VNQ+ECHP+ Q ++ CE G+ I AY+PL
Sbjct: 175 VNQIECHPFNTQPEIRAACEKYGIVIEAYAPL 206
>UniRef50_Q9ZUJ6 Cluster: T2K10.1 protein; n=16; core
eudicotyledons|Rep: T2K10.1 protein - Arabidopsis
thaliana (Mouse-ear cress)
Length = 176
Score = 118 bits (283), Expect = 2e-25
Identities = 63/158 (39%), Positives = 91/158 (57%), Gaps = 4/158 (2%)
Frame = +1
Query: 109 PILGLGTWKS---KPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVV-T 276
P+LG GT S +P + + V +AI +GYRH D + Y E+ +GEA+ + G+V +
Sbjct: 22 PVLGFGTAASPLPEPTMLKETVIEAIKLGYRHFDTSPRYQTEEPIGEALAEAVSLGLVRS 81
Query: 277 REDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSG 456
R + F+T+KLW LV A++ +L NL + YLDLY+IHWP + K FP D+
Sbjct: 82 RSEFFVTTKLWCADAHGGLVVPAIKRSLKNLKLDYLDLYIIHWPVSSKPGKYKFPIDED- 140
Query: 457 KIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQL 570
F +D+ W ME + GL K IGVSNF+ K+L
Sbjct: 141 --DFMPMDFEVVWSEMEECQRLGLAKCIGVSNFSCKKL 176
>UniRef50_Q4PE96 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 293
Score = 118 bits (283), Expect = 2e-25
Identities = 75/201 (37%), Positives = 109/201 (54%), Gaps = 3/201 (1%)
Frame = +1
Query: 109 PILGLGTWKSKPGEVTQAVKDAID-IGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 285
P G+G W + E QA+ +A D GYRH+D A Y NE + GEA+ +E V R +
Sbjct: 28 PRFGIGAWDMRGSECKQALLNAFDKAGYRHVDTARYYRNEADCGEAV----RECSVPRSE 83
Query: 286 LFITSKLW-NTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKI 462
LF T+K++ N R A++++L + YLDL L+H P DG GK
Sbjct: 84 LFYTTKVYLNEMGGGSKTRLAVEDSLAKAGLDYLDLVLLHAP-----DG--------GK- 129
Query: 463 QFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHAT-VKPVVNQVECHPYLN 639
+F +D+W + LV+EG V+S+GVSNF ++ L+ V PV NQ+ECHP+
Sbjct: 130 KFR----LDSWDTLTELVQEGKVRSLGVSNFGPHHIQELIDSKPKVLPVCNQIECHPFFA 185
Query: 640 QKRLKEFCEARGVKITAYSPL 702
QK ++ EA + + AY PL
Sbjct: 186 QKEVRAASEAHSIIVQAYCPL 206
>UniRef50_Q927P9 Cluster: Lin2739 protein; n=12; Bacteria|Rep:
Lin2739 protein - Listeria innocua
Length = 283
Score = 117 bits (282), Expect = 3e-25
Identities = 76/207 (36%), Positives = 108/207 (52%), Gaps = 1/207 (0%)
Frame = +1
Query: 82 VEFNNELKCPILGLGTWK-SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 258
V+ NN ++ PILG GT++ + GE QAVK+AI GYRHID A Y NE+ VG I +
Sbjct: 4 VKLNNGIEVPILGFGTYQITDAGEAEQAVKEAIAAGYRHIDTAQSYMNEEAVGRGIAA-- 61
Query: 259 KEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLF 438
V R++LFIT+K+W V + +L L + Y+DL LIH P
Sbjct: 62 --SGVDRKELFITTKIWVENVSYKGVMSSFDRSLKRLGLDYIDLLLIHQP---------- 109
Query: 439 PTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQV 618
++DV W AME L +G +K+IGVSNF ++ L + P VNQ+
Sbjct: 110 ---------YNDV--YGAWMAMEELQAQGKIKAIGVSNFGVDRVVDLAAFNDITPQVNQI 158
Query: 619 ECHPYLNQKRLKEFCEARGVKITAYSP 699
E +P+ Q + E GV + A++P
Sbjct: 159 EINPFQQQSKNIEALRKEGVAVEAWAP 185
>UniRef50_Q1M4Z6 Cluster: Putative aldo-keto reductase/oxidase; n=1;
Rhizobium leguminosarum bv. viciae 3841|Rep: Putative
aldo-keto reductase/oxidase - Rhizobium leguminosarum
bv. viciae (strain 3841)
Length = 274
Score = 117 bits (282), Expect = 3e-25
Identities = 73/202 (36%), Positives = 108/202 (53%), Gaps = 4/202 (1%)
Frame = +1
Query: 109 PILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 288
P +G GTW E Q V A++ G RHID A YGNE++V I K+ V R ++
Sbjct: 11 PQMGYGTWNRSADEAHQGVIWALEAGCRHIDTAQGYGNEQDVARGI----KDAGVARNEI 66
Query: 289 FITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP-TDQSGKIQ 465
FIT+K+ + P V +++E+L+ L V +DL L+HWP + + +P D G Q
Sbjct: 67 FITTKVKPDNYGPGAVMPSVRESLEKLRVDQVDLLLLHWPSPHNK----YPLADYLG--Q 120
Query: 466 FSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLE---RLLQHATVKPVVNQVECHPYL 636
F++V GL + IGVSNF ++ RLL T+ NQVECH Y+
Sbjct: 121 FAEV------------FDSGLARQIGVSNFTKAMIDESIRLLDSRTI--TTNQVECHVYM 166
Query: 637 NQKRLKEFCEARGVKITAYSPL 702
+ + ++C+ G+ +TAYSPL
Sbjct: 167 QNRPIIDYCQNLGIAVTAYSPL 188
>UniRef50_Q7VHE1 Cluster: Putative uncharacterized protein; n=1;
Helicobacter hepaticus|Rep: Putative uncharacterized
protein - Helicobacter hepaticus
Length = 270
Score = 116 bits (280), Expect = 4e-25
Identities = 68/203 (33%), Positives = 112/203 (55%)
Frame = +1
Query: 91 NNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 270
NN +K PILGLGT+ +A+ +AI++GYR D A +Y NE E+G AI + +K G
Sbjct: 7 NNGVKMPILGLGTYSLTGKAGQKAMSEAIEVGYRLFDSAQMYNNEAELGAAINAAVKGG- 65
Query: 271 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQ 450
+ RE+ FI +KL + DL + +++++L L + Y+D LIH P Y + +++
Sbjct: 66 IKREEFFIQTKLLES-SSEDLAKKSIEKSLKTLGLDYIDSLLIHMP--YSQSKAMY---- 118
Query: 451 SGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHP 630
+AME K+G+++ IG+SNF +K ++ V P +NQ E H
Sbjct: 119 ---------------RAMESFYKQGILRVIGISNFGAKAYSEFVKSCEVIPAINQCETHL 163
Query: 631 YLNQKRLKEFCEARGVKITAYSP 699
L QK L+E +++ + ++SP
Sbjct: 164 LLQQKPLREAMKSKKTLLQSWSP 186
>UniRef50_Q5KD52 Cluster: Oxidoreductase, putative; n=1;
Filobasidiella neoformans|Rep: Oxidoreductase, putative
- Cryptococcus neoformans (Filobasidiella neoformans)
Length = 321
Score = 116 bits (280), Expect = 4e-25
Identities = 92/236 (38%), Positives = 122/236 (51%), Gaps = 26/236 (11%)
Frame = +1
Query: 73 VPFVEF--NNELKCPILGLGTWKSKPGEVTQ-AVKDAIDIGYRHIDCAY---VYGNEKEV 234
+PF E N+ + P + GTWK P EVT V AID+G+ HID A VY NE+EV
Sbjct: 1 MPFGEITLNDGHRIPAIAFGTWKI-PKEVTPFQVGQAIDVGFDHIDTAQGRIVYHNEEEV 59
Query: 235 GEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA 414
G+AI KE ++R L++T+K W+ R ++ E+L+ L ++YLDLYLIH PQ
Sbjct: 60 GQAI----KESGLSRNQLWVTTK-WSGIDGKG-ARQSIGESLEKLGLEYLDLYLIHSPQV 113
Query: 415 YKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVS--------------- 549
K D WK +E L KEG KSIGVS
Sbjct: 114 TKG------------------DIKGAWKELETLQKEGKTKSIGVSKQVYYQTIFFASLSD 155
Query: 550 ---NFNSKQLERLLQHATVKPVVNQVECHPYLNQKR--LKEFCEARGVKITAYSPL 702
+FN +QL+ LL HATVKPVVNQ+ HPY+ + L E+ E + + YS L
Sbjct: 156 VWDSFNKEQLQELLAHATVKPVVNQILLHPYVITRTAPLLEYLEEQNIVAEGYSTL 211
>UniRef50_A3VHZ9 Cluster: Oxidoreductase; n=1; Rhodobacterales
bacterium HTCC2654|Rep: Oxidoreductase - Rhodobacterales
bacterium HTCC2654
Length = 278
Score = 116 bits (279), Expect = 6e-25
Identities = 73/215 (33%), Positives = 111/215 (51%)
Frame = +1
Query: 61 KMSSVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGE 240
++ P V N ++ P LGLGTW E +AV AI+ GYR ID A Y NE VG+
Sbjct: 3 RIDPAPTVTLANGVEMPQLGLGTWPMTDDEAAKAVATAIETGYRLIDTAENYKNETGVGQ 62
Query: 241 AITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYK 420
I++ V R+++F+T+K+ +H D R A + +L+ L + Y+DL+LIHWP
Sbjct: 63 G----IRDAGVARDEVFLTTKMNKQWHSVDGARRACEASLERLGLDYIDLFLIHWPN--- 115
Query: 421 EDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVK 600
DQ YV+ ++ + L+ GLV++IG SNF L L V
Sbjct: 116 -------PDQG--------TYVEAFEGLTRLLDAGLVRAIGTSNFLPHHLNDLFAAGFV- 159
Query: 601 PVVNQVECHPYLNQKRLKEFCEARGVKITAYSPLG 705
P VNQ++ PY + + A+G+ ++SP+G
Sbjct: 160 PHVNQIQLDPYHLRPDITAIHAAKGIVTESWSPIG 194
>UniRef50_A0L1A2 Cluster: Aldo/keto reductase; n=8;
Gammaproteobacteria|Rep: Aldo/keto reductase -
Shewanella sp. (strain ANA-3)
Length = 280
Score = 116 bits (279), Expect = 6e-25
Identities = 72/198 (36%), Positives = 106/198 (53%), Gaps = 1/198 (0%)
Frame = +1
Query: 109 PILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 288
P+LG GT++ K AV A++ G RHID A +YGNE+ VG+AI + + RE+L
Sbjct: 18 PMLGTGTFRLKDNAAFDAVLMALEEGSRHIDTAQIYGNEQAVGDAINT----SGIPREEL 73
Query: 289 FITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQF 468
FIT+K+W + ++ ++L L +YLDL LIHWP E
Sbjct: 74 FITTKVWTENLTKERFETSVIDSLTALQTKYLDLLLIHWPLNSDEP-------------- 119
Query: 469 SDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPV-VNQVECHPYLNQK 645
S V+Y+ KA ++ +GL + IGVSNF + QL + + + NQVE HPYL +
Sbjct: 120 SMVEYLSELKA---VLDKGLTRRIGVSNFTNAQLAQAIAILGEGVIYTNQVEVHPYLINR 176
Query: 646 RLKEFCEARGVKITAYSP 699
++ +FC V +T Y P
Sbjct: 177 KVTDFCRQHNVLVTGYMP 194
>UniRef50_A0AWM8 Cluster: Aldo/keto reductase; n=4;
Actinomycetales|Rep: Aldo/keto reductase - Arthrobacter
sp. (strain FB24)
Length = 287
Score = 116 bits (279), Expect = 6e-25
Identities = 74/213 (34%), Positives = 107/213 (50%)
Frame = +1
Query: 67 SSVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAI 246
S +P ++ + P LGLGTW E AV+ A+ GYR +D A+ Y NE+ VG
Sbjct: 11 SDIPRLKLPHGHTIPRLGLGTWPMLEDECETAVRFALQSGYRLVDTAFQYRNEEAVGRG- 69
Query: 247 TSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKED 426
I+ V R +LFI+SK H D V+ A E+L L + +LD+++ HW
Sbjct: 70 ---IRTAGVPRSELFISSKFNKESHSIDGVQRAYDESLRKLGLDHLDMFMCHW------- 119
Query: 427 GSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPV 606
P GK YVD WK + L++EG VK+IGVSNF L+ ++ V P
Sbjct: 120 ----PVPALGK-------YVDAWKGLVKLLEEGRVKAIGVSNFKPAHLKDIIDATGVVPD 168
Query: 607 VNQVECHPYLNQKRLKEFCEARGVKITAYSPLG 705
VNQ++ P L + + G+ A+SP+G
Sbjct: 169 VNQIQLSPDLARTEPRAVHRLLGIVTEAWSPIG 201
>UniRef50_A5DRJ6 Cluster: Putative uncharacterized protein; n=4;
Pichia guilliermondii|Rep: Putative uncharacterized
protein - Pichia guilliermondii (Yeast) (Candida
guilliermondii)
Length = 287
Score = 116 bits (279), Expect = 6e-25
Identities = 71/207 (34%), Positives = 113/207 (54%), Gaps = 4/207 (1%)
Frame = +1
Query: 94 NELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI-KEGV 270
N + P G+G + + V+ A+D+GYR ID A Y NE+E GE I + + K+
Sbjct: 14 NGSRIPACGVGVYLLPASQTAGIVEKALDVGYRLIDTAQEYENERETGEGIKAWLGKDKN 73
Query: 271 VTREDLFITSKLWNTFHRPDLVRGALQETLDNL-NVQYLDLYLIHWPQAYKEDGSLFPTD 447
RED+ T+K+ N D +L+E+L+ + +++Y+DL LIH P + K+
Sbjct: 74 NKREDVLYTTKITNLNQGYDRTWRSLKESLNKVKHLEYIDLVLIHDPLSDKKTR------ 127
Query: 448 QSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLL--QHATVKPVVNQVE 621
++TWKA++ V G+VKSIGVSNF ++ L + KP+VNQ+E
Sbjct: 128 ------------IETWKALQEAVDSGMVKSIGVSNFGKHHIQELYDWEGLKYKPIVNQIE 175
Query: 622 CHPYLNQKRLKEFCEARGVKITAYSPL 702
P+L +K L ++C+ G+ + AY PL
Sbjct: 176 LSPWLMRKDLVDYCQNLGIVLEAYCPL 202
>UniRef50_Q5V663 Cluster: Aldehyde reductase; n=6;
Halobacteriaceae|Rep: Aldehyde reductase - Haloarcula
marismortui (Halobacterium marismortui)
Length = 279
Score = 116 bits (279), Expect = 6e-25
Identities = 68/199 (34%), Positives = 100/199 (50%), Gaps = 1/199 (0%)
Frame = +1
Query: 109 PILGLGTWKSKPGE-VTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 285
P+LGLGTW+++ E ++V+ A++ GYRHID A Y NE VG+ I + V R+D
Sbjct: 18 PMLGLGTWQNEDAEQCAESVRTALEAGYRHIDTAQAYDNESAVGDGIAA----ADVDRDD 73
Query: 286 LFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQ 465
+F+ +K+W + D V +E+LD L V +DL +HW E P
Sbjct: 74 IFLATKVWISNLSHDDVIETTEESLDKLGVDSVDLLYVHWAAGEYEPEETLP-------- 125
Query: 466 FSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQK 645
A + LV GL+ ++GVSNF +E + NQVE HP+L Q
Sbjct: 126 -----------AFDELVDRGLIDNVGVSNFEPHHVETAMDVLDAPVFANQVETHPFLQQS 174
Query: 646 RLKEFCEARGVKITAYSPL 702
L+E + ++ AYSPL
Sbjct: 175 ELREHAAEQDYELVAYSPL 193
>UniRef50_Q0SFM4 Cluster: Probable 2,5-didehydrogluconate reductase;
n=1; Rhodococcus sp. RHA1|Rep: Probable
2,5-didehydrogluconate reductase - Rhodococcus sp.
(strain RHA1)
Length = 265
Score = 115 bits (277), Expect = 1e-24
Identities = 74/199 (37%), Positives = 103/199 (51%)
Frame = +1
Query: 109 PILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 288
P LGLGTW + T+AV I+ GYR ID A +Y NE VG A+ E V RE+L
Sbjct: 5 PPLGLGTWPLTGPDATRAVLSGIEAGYRLIDTATIYDNEDAVGVALA----ECGVPREEL 60
Query: 289 FITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQF 468
F+T+KL + H +RGA++ +L NL + LDL+LIHWP P
Sbjct: 61 FVTTKLRGSDHVSGDIRGAVERSLKNLGLDRLDLFLIHWP---------LPRHNR----- 106
Query: 469 SDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKR 648
YV ++AM GLV+ +GVSNF L R++ P VNQ++ P L +
Sbjct: 107 ----YVAAFEAMLACRDAGLVRHVGVSNFLETHLRRVVAETGESPAVNQIQMDPSLARLP 162
Query: 649 LKEFCEARGVKITAYSPLG 705
++ + GV ++SPLG
Sbjct: 163 VRRADDELGVSTQSWSPLG 181
>UniRef50_Q4V008 Cluster: Oxidoreductase; n=4; Proteobacteria|Rep:
Oxidoreductase - Xanthomonas campestris pv. campestris
(strain 8004)
Length = 267
Score = 114 bits (275), Expect = 2e-24
Identities = 69/199 (34%), Positives = 105/199 (52%), Gaps = 1/199 (0%)
Frame = +1
Query: 109 PILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 288
P GLGT++ K V +V++A+ +GYR ID A +Y NE +VG+AI + V R+ L
Sbjct: 4 PAFGLGTFRLKDQVVIDSVRNALALGYRAIDTAQIYDNEAQVGQAIA----DAGVPRDQL 59
Query: 289 FITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQF 468
F+T+K+W D ++ +LQE+L L Y+DL LIHWP P DQ
Sbjct: 60 FVTTKIWVDRFSRDTLQPSLQESLRKLGTDYVDLTLIHWPS---------PKDQ------ 104
Query: 469 SDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPV-VNQVECHPYLNQK 645
V + +A+ +GL ++IGVSNF + ++ + NQ+E HPYL +
Sbjct: 105 --VPMREYLEALADAKAQGLTRAIGVSNFTIALTRQAIEILGADAIATNQIEVHPYLQNR 162
Query: 646 RLKEFCEARGVKITAYSPL 702
L F +G+ +T+Y L
Sbjct: 163 TLIAFLREQGIHVTSYMTL 181
>UniRef50_A4YQ04 Cluster: 2,5-diketo-D-gluconate reductase B; n=15;
Proteobacteria|Rep: 2,5-diketo-D-gluconate reductase B -
Bradyrhizobium sp. (strain ORS278)
Length = 273
Score = 114 bits (274), Expect = 2e-24
Identities = 66/201 (32%), Positives = 104/201 (51%)
Frame = +1
Query: 100 LKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTR 279
++ P LGLGT++ + AV+ A+ +GYRHID A +Y NE +G A+ + + R
Sbjct: 9 VRLPKLGLGTFRMQGTVCRDAVESALALGYRHIDTAEMYANEDAIGAALAA----AQIAR 64
Query: 280 EDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGK 459
EDL +T+K+W PD +R A +L L + ++DLYLIHWP G P
Sbjct: 65 EDLHVTTKVWPENLAPDAIRRAFDTSLKKLRLDFVDLYLIHWPAT----GMNLPA----- 115
Query: 460 IQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLN 639
+ + L +EG ++IGV+NF L++ ++ NQVE H L+
Sbjct: 116 ----------AMETLMALKQEGRTRAIGVANFTVALLKQAVEDIQAPVACNQVEYHVMLD 165
Query: 640 QKRLKEFCEARGVKITAYSPL 702
Q +L + ++R + + AY PL
Sbjct: 166 QSKLMAYMKSRSIPLVAYCPL 186
>UniRef50_Q5FK99 Cluster: Oxidoreductase aldo-keto reductase family;
n=5; Lactobacillus|Rep: Oxidoreductase aldo-keto
reductase family - Lactobacillus acidophilus
Length = 289
Score = 113 bits (273), Expect = 3e-24
Identities = 75/213 (35%), Positives = 110/213 (51%), Gaps = 1/213 (0%)
Frame = +1
Query: 64 MSSVPFVEFNNELKCPILGLGTWK-SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGE 240
M+ +P ++ N+ + P LG G ++ S E +AV+ AI GYR ID A Y N+ VGE
Sbjct: 1 MTDIPKIKLNDGNEIPQLGFGVFQISNHDEAVKAVESAISNGYRLIDTAEAYNNQTAVGE 60
Query: 241 AITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYK 420
AI K V R+D+F+T+KLW + + A+ E L L Y+D+ L+H QAY
Sbjct: 61 AI----KNSDVNRDDIFLTTKLWVSNFTYEKASKAIDEDLKELGTDYIDMMLLH--QAYG 114
Query: 421 EDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVK 600
D W+A+E K G KSIGVSNF QL L + VK
Sbjct: 115 -------------------DVAGAWRALEDAQKAGKTKSIGVSNFWPDQLMNLQLMSNVK 155
Query: 601 PVVNQVECHPYLNQKRLKEFCEARGVKITAYSP 699
PVVNQ+E +P+ ++ ++ + V + A++P
Sbjct: 156 PVVNQIEVNPWFQREPEVKWNQKDDVAVEAWAP 188
>UniRef50_Q4DJ59 Cluster: Aldo/keto reductase, putative; n=2;
Trypanosoma|Rep: Aldo/keto reductase, putative -
Trypanosoma cruzi
Length = 322
Score = 113 bits (271), Expect = 5e-24
Identities = 72/223 (32%), Positives = 113/223 (50%), Gaps = 12/223 (5%)
Frame = +1
Query: 70 SVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAIT 249
++P +E + ++ P +G+GT++ E AV A+ +G+R +D A Y NE+ VG A
Sbjct: 14 ALPLLESSGGMRIPHMGVGTYELYGDESRIAVLAALRLGFRLVDTAAGYHNEEHVGAA-- 71
Query: 250 SKIKEGVVTREDLFITSKLW-NTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKED 426
I+E V RE+LF+ K+ +LV ++E++ L + Y D LIHWP
Sbjct: 72 --IEESGVQREELFVVVKIAPKAMASEELVEKGIRESVRKLRIAYADCVLIHWPGC---- 125
Query: 427 GSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHAT---- 594
G L P + G WK M+ L KEG+++ +GVSNF + L+ +A
Sbjct: 126 GGLKPEEAEGHRAARH----RCWKVMQALKKEGIIRHLGVSNFAPRHFPHLVGNAAEEAH 181
Query: 595 -------VKPVVNQVECHPYLNQKRLKEFCEARGVKITAYSPL 702
+PV+NQ+E HP Q+ +FC R + + YSPL
Sbjct: 182 LFDAANPCRPVINQIELHPLCVQQEACDFCRERDIILQQYSPL 224
>UniRef50_A7TLC4 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 313
Score = 112 bits (269), Expect = 9e-24
Identities = 81/224 (36%), Positives = 115/224 (51%), Gaps = 15/224 (6%)
Frame = +1
Query: 79 FVEFNNELKCP---ILGLGT-WKSKPG-------EVTQAVKDAIDI-GYRHIDCAYVYGN 222
F + NN + P I+G GT W +PG E+ + +K A+ + G HID A YG
Sbjct: 7 FFDLNNGNQIPSISIIGTGTRWFKRPGSEHTFSDELVEQIKYALSLPGIIHIDAAECYGT 66
Query: 223 EKEVGEAITSKIKEGVVTREDLFITSKL-WNTFHRPDLVRGALQETLDNLNVQYLDLYLI 399
E+ +A+ KE R ++FIT K T D + G L L L + Y+DLYLI
Sbjct: 67 YPELAKAL----KESSKPRSEIFITDKYSTQTKFTNDPIEG-LNTGLKTLGLDYVDLYLI 121
Query: 400 HWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERL 579
H P F + G + V WK ME L KEG KSIGVSNF+ K +E +
Sbjct: 122 HSP--------FFDPEFKGSLTLEKV-----WKDMETLYKEGKAKSIGVSNFSVKNIEEI 168
Query: 580 LQHATVKPVVNQVECHPYLNQKR--LKEFCEARGVKITAYSPLG 705
L+ A +KP VNQ+E + +L + + +C+ +++ AYSPLG
Sbjct: 169 LKIAGIKPQVNQIEFNAFLQNQTPGIVNYCQKNNIQLEAYSPLG 212
>UniRef50_Q5UYI9 Cluster: Oxidoreductase; n=1; Haloarcula
marismortui|Rep: Oxidoreductase - Haloarcula marismortui
(Halobacterium marismortui)
Length = 264
Score = 111 bits (268), Expect = 1e-23
Identities = 68/198 (34%), Positives = 104/198 (52%)
Frame = +1
Query: 112 ILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDLF 291
++G+GTW V ++V+ +++GY H+D A Y NE E+GEA+ RED+F
Sbjct: 1 MVGVGTWDIDGDTVQKSVRAGLNVGYAHVDTAEGYKNESEIGEALAD------YDREDVF 54
Query: 292 ITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFS 471
+TSK+ + V A + +LD L YLDLYL+HWP + + I+
Sbjct: 55 LTSKVLPKHLDYESVIEACEASLDRLGTDYLDLYLVHWP------------NPATSIR-- 100
Query: 472 DVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRL 651
+T AM L +G ++++GVSNF++ QL A V VNQ+E HP+ Q ++
Sbjct: 101 -----ETMNAMATLHDQGKIRNVGVSNFSAYQLGAAQHVADVPIAVNQIEYHPWNTQDQV 155
Query: 652 KEFCEARGVKITAYSPLG 705
EFC + A +PLG
Sbjct: 156 VEFCRDTDTVVEAAAPLG 173
>UniRef50_Q5K8C5 Cluster: Aldo-keto reductase, putative; n=1;
Filobasidiella neoformans|Rep: Aldo-keto reductase,
putative - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 303
Score = 111 bits (267), Expect = 2e-23
Identities = 68/198 (34%), Positives = 98/198 (49%)
Frame = +1
Query: 109 PILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 288
P GLG ++ E VK A++ GYRH+D A Y NE G+AI +K +RE++
Sbjct: 42 PQFGLGVYEMNDKETYDCVKWALEAGYRHVDTAEWYENEAPCGKAIADFLKATGTSREEI 101
Query: 289 FITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQF 468
F+TSKL N L+ +L V+Y DLYL+H + G +
Sbjct: 102 FLTSKLKNNSSYEQAFVD-LKGSLKRSGVEYFDLYLMH-------------SAIGGPVIR 147
Query: 469 SDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKR 648
+V WKA+ +GLVKSIGVSNF K ++ + P VNQV+ HP++
Sbjct: 148 KNV-----WKALCDAQSQGLVKSIGVSNFGKKHIQEFIDQKVPLPTVNQVDLHPFMRHPE 202
Query: 649 LKEFCEARGVKITAYSPL 702
+ E CE + + A+ PL
Sbjct: 203 IVEICEQNEILLEAWGPL 220
>UniRef50_Q8Y463 Cluster: Lmo2592 protein; n=40; Bacteria|Rep:
Lmo2592 protein - Listeria monocytogenes
Length = 283
Score = 111 bits (266), Expect = 2e-23
Identities = 76/207 (36%), Positives = 104/207 (50%), Gaps = 1/207 (0%)
Frame = +1
Query: 82 VEFNNELKCPILGLGTWK-SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 258
V+ NN ++ PILG GT++ + E AVKDAI GYRHID A Y NE+ VG I +
Sbjct: 4 VKLNNGVEVPILGFGTYQITDAAEAEHAVKDAIKAGYRHIDTAQSYMNEEAVGRGIAA-- 61
Query: 259 KEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLF 438
V R++LFIT+K+W V + +L L + Y+DL LIH P
Sbjct: 62 --SGVDRKELFITTKIWVENVSYKGVMSSFDRSLKRLGLDYVDLLLIHQP---------- 109
Query: 439 PTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQV 618
F+DV W AME L G +++IGVSNF+ ++ L V P VNQ+
Sbjct: 110 ---------FNDV--YGAWIAMEELQASGKIRAIGVSNFSPDRVIDLAAFNEVTPQVNQI 158
Query: 619 ECHPYLNQKRLKEFCEARGVKITAYSP 699
E +P+ Q GV I A++P
Sbjct: 159 EVNPFQQQTANLAILRKEGVAIEAWAP 185
>UniRef50_Q7XY49 Cluster: Mannose 6-phosphate reductase; n=1;
Griffithsia japonica|Rep: Mannose 6-phosphate reductase
- Griffithsia japonica (Red alga)
Length = 174
Score = 110 bits (265), Expect = 3e-23
Identities = 53/99 (53%), Positives = 65/99 (65%)
Frame = +1
Query: 103 KCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRE 282
K P+ G GTWK+ E QAV A+ GYRHIDCA VY NE VG AI+ I GVV RE
Sbjct: 13 KMPLNGFGTWKASVEETEQAVTAALRAGYRHIDCAAVYWNEAAVGTAISKAISGGVVKRE 72
Query: 283 DLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLI 399
DLFITSK+WNT H D V + +++L + V Y DL+L+
Sbjct: 73 DLFITSKVWNTCHATDKVVDSCRQSLKDHQVDYFDLFLV 111
Score = 47.6 bits (108), Expect = 3e-04
Identities = 22/53 (41%), Positives = 32/53 (60%)
Frame = +1
Query: 526 LVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKRLKEFCEARGVKI 684
LV+ IGVSN++ L L +A +KP VNQ E H Y + +L++ C GV +
Sbjct: 110 LVRDIGVSNYSVALLVDTLNYARIKPSVNQCEAHVYFARPQLRDVCREFGVHL 162
>UniRef50_A3VRL4 Cluster: Putative uncharacterized protein; n=1;
Parvularcula bermudensis HTCC2503|Rep: Putative
uncharacterized protein - Parvularcula bermudensis
HTCC2503
Length = 278
Score = 109 bits (263), Expect = 5e-23
Identities = 64/199 (32%), Positives = 100/199 (50%)
Frame = +1
Query: 109 PILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 288
P LG GTW+ + + + + AI+ GYRHID A +Y NEK+VGE IK+ + R++L
Sbjct: 12 PRLGFGTWQLEGEDARTSTRTAIETGYRHIDGAAIYKNEKKVGEG----IKDSGIPRDEL 67
Query: 289 FITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQF 468
F+T+K+WN + A+ E+LD L + Y++L L+HWP
Sbjct: 68 FVTTKIWNEDIQKGRHSEAVDESLDRLGLDYVNLILLHWP-------------------I 108
Query: 469 SDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECHPYLNQKR 648
+D+ D + + + G K IG+SN+N Q + + Q E HP L+Q
Sbjct: 109 NDMPIADQVGPLAEIKRSGRAKLIGISNYNQAQFLEAVSASEEPLAAIQCEYHPMLDQDP 168
Query: 649 LKEFCEARGVKITAYSPLG 705
+ + + T+YSPLG
Sbjct: 169 ILKTARGFDMMFTSYSPLG 187
>UniRef50_Q21274 Cluster: Putative uncharacterized protein; n=1;
Caenorhabditis elegans|Rep: Putative uncharacterized
protein - Caenorhabditis elegans
Length = 301
Score = 109 bits (262), Expect = 7e-23
Identities = 65/208 (31%), Positives = 114/208 (54%), Gaps = 2/208 (0%)
Frame = +1
Query: 85 EFNNELKCPILGLGTWKSKPGE-VTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 261
+F++ + P +GLG + + + + +++ A+ GYR D A +Y NE +G ++ +
Sbjct: 13 KFSDGYEMPKIGLGISRIETQQDLDVSIEAALKSGYRQFDTANLYKNETFLGNSLKKYLP 72
Query: 262 EGVVTREDLFITSKLWNTFHRP-DLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLF 438
+ +TRED+FIT+K+ + L +L L Y+DL LIH+P+ ++ G+
Sbjct: 73 QFGLTREDVFITTKVRTLNENTVEETEKQLANSLATLQTDYVDLLLIHYPRD-RDTGN-- 129
Query: 439 PTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQV 618
D +I S V W+ +E + G V+SIGVSN+ L + ++A ++PV+NQ
Sbjct: 130 --DDDYEINKSRRKIV--WQTLEKAKESGRVRSIGVSNYEVYHLVEMFEYAKIRPVLNQY 185
Query: 619 ECHPYLNQKRLKEFCEARGVKITAYSPL 702
E PYL + LK+FC+ + + +YS L
Sbjct: 186 EYQPYLTRPTLKKFCDLNNIVVQSYSSL 213
>UniRef50_Q5KKZ8 Cluster: Aldo-keto reductase, putative; n=2;
Filobasidiella neoformans|Rep: Aldo-keto reductase,
putative - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 293
Score = 109 bits (262), Expect = 7e-23
Identities = 75/205 (36%), Positives = 106/205 (51%), Gaps = 7/205 (3%)
Frame = +1
Query: 109 PILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 288
P LG G ++++ E AVK AID GYRH+D A Y NE+ VG A I+ V R +
Sbjct: 18 PRLGFGVYQARSKECEDAVKKAIDTGYRHVDTAQAYHNEENVGRA----IRNSGVPRPSV 73
Query: 289 FITSKLW--NTFHRPDLVRGALQETLDNL-----NVQYLDLYLIHWPQAYKEDGSLFPTD 447
F+TSK +T + P V ++++L + + Y+DL LIH P +E
Sbjct: 74 FLTSKYMPSHTVYSPTEVLDVVRKSLKKVDRCGDDKPYIDLMLIHAPWGGEE-------- 125
Query: 448 QSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVECH 627
G+ + W+A+ KEG VK IGVSNF L+ L P VNQ+E H
Sbjct: 126 --GR--------KNNWEALTIAQKEGWVKDIGVSNFGIHHLKAL---PPPVPAVNQIELH 172
Query: 628 PYLNQKRLKEFCEARGVKITAYSPL 702
P+ Q+ + ++CE G+ I AYSPL
Sbjct: 173 PFCQQRDIVKYCEEHGIAIEAYSPL 197
>UniRef50_Q9X265 Cluster: Oxidoreductase, aldo/keto reductase
family; n=2; Thermotoga|Rep: Oxidoreductase, aldo/keto
reductase family - Thermotoga maritima
Length = 274
Score = 108 bits (260), Expect = 1e-22
Identities = 78/210 (37%), Positives = 108/210 (51%), Gaps = 12/210 (5%)
Frame = +1
Query: 109 PILGLGTWK---------SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 261
P LGLGTW S+ E+ + +K AI +GY HID A YG E I IK
Sbjct: 14 PALGLGTWGIGGFETPDYSRDEEMVELLKTAIKMGYTHIDTAEYYGGG-HTEELIGKAIK 72
Query: 262 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 441
+ REDLFI SK+W T R D + +L+ TL L+ Y+DLYLIHWP
Sbjct: 73 D--FRREDLFIVSKVWPTHLRRDDLLRSLENTLKRLDTDYVDLYLIHWPN---------- 120
Query: 442 TDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVE 621
++ +T AM V++GL++ IGVSNF+ + LE + + V +QV+
Sbjct: 121 ---------PEIPLEETLSAMAEGVRQGLIRYIGVSNFDRRLLEEAISKSQEPIVCDQVK 171
Query: 622 CH-PYLNQKR--LKEFCEARGVKITAYSPL 702
+ + +R L EFC+ GV + AYSPL
Sbjct: 172 YNIEDRDPERDGLLEFCQKNGVTLVAYSPL 201
>UniRef50_Q0CK00 Cluster: Predicted protein; n=1; Aspergillus
terreus NIH2624|Rep: Predicted protein - Aspergillus
terreus (strain NIH 2624)
Length = 292
Score = 108 bits (259), Expect = 2e-22
Identities = 73/208 (35%), Positives = 110/208 (52%), Gaps = 10/208 (4%)
Frame = +1
Query: 109 PILGLGT----WKSKPGEVT-----QAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 261
PILG GT +K P + T + +K A++ G+ HID A YG E+EVG A I+
Sbjct: 15 PILGFGTGTAWYKDDPNDPTNPELIEVLKAALEKGFHHIDAADSYGTEREVGIA----IR 70
Query: 262 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 441
E + RE LFIT+K+ + V GAL +L+ L + Y+DLYL+H P + P
Sbjct: 71 ESGIPREQLFITTKVLEGWKD---VPGALDASLERLQLDYVDLYLLHNPY-------VIP 120
Query: 442 TDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQVE 621
+D+ WK +E + G +SIGVSNF LE +L+ +V P +NQ+E
Sbjct: 121 -------NLTDIQ--SAWKGLEAVKATGKARSIGVSNFQRNHLEAILETCSVVPAINQLE 171
Query: 622 CHPYLNQKR-LKEFCEARGVKITAYSPL 702
HPYL + + RG++++++ L
Sbjct: 172 YHPYLQRSHDFIPWMRERGIEVSSFKTL 199
>UniRef50_Q5NLW3 Cluster: Putative oxidoreductase; n=1; Zymomonas
mobilis|Rep: Putative oxidoreductase - Zymomonas mobilis
Length = 273
Score = 107 bits (256), Expect = 4e-22
Identities = 73/214 (34%), Positives = 102/214 (47%)
Frame = +1
Query: 64 MSSVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEA 243
M V V N+ P +G G ++ P + V D+GYR +D A Y NE+ VGE
Sbjct: 1 MVPVKNVVLNDGHSMPAIGQGVYQLNPAQAESMVALGYDLGYRAVDTAAWYENEEGVGEG 60
Query: 244 ITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKE 423
+ S+ FIT+KL AL +++ NL V L+LYLIHWP
Sbjct: 61 LRSRHARS-------FITTKLMPQDMGRVNCFVALDKSIRNLGVTSLNLYLIHWP----- 108
Query: 424 DGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKP 603
Q K Y +TW+ + + G SIGVSNF L+ ++ + V P
Sbjct: 109 -------GQDRK------RYEETWQTLIQIRAIGKASSIGVSNFTIDHLDHIIADSGVVP 155
Query: 604 VVNQVECHPYLNQKRLKEFCEARGVKITAYSPLG 705
VNQ+E HPY QK L+ + RG+ T++SPLG
Sbjct: 156 AVNQIELHPYFQQKELRAYHAERGIVTTSWSPLG 189
>UniRef50_Q75E75 Cluster: ABL209Cp; n=1; Eremothecium gossypii|Rep:
ABL209Cp - Ashbya gossypii (Yeast) (Eremothecium
gossypii)
Length = 310
Score = 106 bits (254), Expect = 6e-22
Identities = 66/212 (31%), Positives = 113/212 (53%), Gaps = 4/212 (1%)
Frame = +1
Query: 79 FVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 258
F ++ + P +GLG ++ V V +A+++GYR D A Y NE V I + +
Sbjct: 12 FRRLSDGTQIPSVGLGVYQVSEQTVQDLVYEALEVGYRLFDSAQAYHNEDGVARGIAAWL 71
Query: 259 KEGVVTR-EDLFITSKLWNTFHRPDLVRGALQETLDNLN-VQYLDLYLIHWPQAYKEDGS 432
K R ED++ T+K+ H + + +L+++L + Y+DL L+H P +
Sbjct: 72 KHAPGRRREDVYFTTKINTQNHGYEATKKSLEKSLHAAGPLGYIDLVLVHAPMS------ 125
Query: 433 LFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLL--QHATVKPV 606
D++ ++ TW+A+E V EG V+SIGVSN+ + L LL + ++PV
Sbjct: 126 ----DRTRRL--------GTWQALEEAVVEGQVRSIGVSNYGQQHLSELLGWEGLKIRPV 173
Query: 607 VNQVECHPYLNQKRLKEFCEARGVKITAYSPL 702
VNQVE +P+L ++ L ++C + + A+SPL
Sbjct: 174 VNQVEINPWLCRQELVQYCRENNIAVQAFSPL 205
>UniRef50_A7SGW6 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 264
Score = 105 bits (253), Expect = 8e-22
Identities = 66/208 (31%), Positives = 109/208 (52%)
Frame = +1
Query: 79 FVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 258
FV N+ K P+ GLG ++ + G A+ GYR +D A +Y NEKEVG A+
Sbjct: 12 FVTLNDGRKMPLFGLGVFRLETG-CEDVCLFALKNGYRMLDTADIYQNEKEVGSAVR--- 67
Query: 259 KEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLF 438
K G + RED+++T+KL + +E++ L++ Y+DL+LIH P
Sbjct: 68 KSG-LKREDIYVTTKLKPSEEGHSNALKYAKESIKKLDIGYVDLFLIHTP---------- 116
Query: 439 PTDQSGKIQFSDVDYVDTWKAMEPLVKEGLVKSIGVSNFNSKQLERLLQHATVKPVVNQV 618
+ G I + + A+ L +EGL++S+GVSNF LE L + P +NQ+
Sbjct: 117 ---RPGNI-------IAAYDALLTLKEEGLIRSVGVSNFGVHHLEELRKAGCRTPAINQI 166
Query: 619 ECHPYLNQKRLKEFCEARGVKITAYSPL 702
E +P+ Q+ + ++C G+ + Y+P+
Sbjct: 167 EINPFWRQEEIIKYCNKHGITVEGYAPV 194
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 735,100,273
Number of Sequences: 1657284
Number of extensions: 16103558
Number of successful extensions: 65867
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 59643
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 65069
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 57851245060
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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