Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= bmov12f24
(541 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q7PCV3 Cluster: ENSANGP00000031808; n=9; Endopterygota|... 217 2e-55
UniRef50_Q2LZ66 Cluster: GA19341-PA; n=2; Endopterygota|Rep: GA1... 208 6e-53
UniRef50_Q9VTL0 Cluster: CG6083-PA; n=4; Diptera|Rep: CG6083-PA ... 204 8e-52
UniRef50_P45376 Cluster: Aldose reductase; n=21; Bilateria|Rep: ... 204 8e-52
UniRef50_P15121 Cluster: Aldose reductase; n=72; Eumetazoa|Rep: ... 200 2e-50
UniRef50_UPI00015B56A2 Cluster: PREDICTED: similar to GA10458-PA... 187 1e-46
UniRef50_Q8CI22 Cluster: 2310005E10Rik protein; n=30; Tetrapoda|... 186 3e-46
UniRef50_Q9NAI5 Cluster: Putative uncharacterized protein; n=3; ... 182 6e-45
UniRef50_P14550 Cluster: Alcohol dehydrogenase [NADP+]; n=44; Bi... 174 1e-42
UniRef50_Q7QK25 Cluster: ENSANGP00000019775; n=2; Anopheles gamb... 171 1e-41
UniRef50_Q17DN0 Cluster: Aldo-keto reductase; n=5; Culicidae|Rep... 168 6e-41
UniRef50_A5KSS3 Cluster: Aldehyde reductase; n=1; candidate divi... 160 2e-38
UniRef50_Q0VGY1 Cluster: 3-alpha-hydroxysteroid dehydrogenase; n... 160 2e-38
UniRef50_Q8K023 Cluster: Aldo-keto reductase family 1 member C18... 157 1e-37
UniRef50_UPI0000588153 Cluster: PREDICTED: hypothetical protein;... 157 2e-37
UniRef50_Q2S340 Cluster: Aldehyde reductase; n=10; Bacteria|Rep:... 155 6e-37
UniRef50_Q96JD6-2 Cluster: Isoform 2 of Q96JD6 ; n=4; Catarrhini... 154 1e-36
UniRef50_Q54B70 Cluster: Aldehyde reductase; n=2; Dictyostelium ... 154 1e-36
UniRef50_Q96JD6 Cluster: Aldo-keto reductase family 1 member C-l... 154 1e-36
UniRef50_Q7QVQ9 Cluster: GLP_302_44328_45269; n=1; Giardia lambl... 153 2e-36
UniRef50_Q7JVH6 Cluster: LD24696p; n=2; Sophophora|Rep: LD24696p... 152 6e-36
UniRef50_A2QBD7 Cluster: Catalytic activity: an alcohol + NADP(+... 151 1e-35
UniRef50_UPI000065D0BD Cluster: Homolog of Homo sapiens "AKR1B1 ... 151 1e-35
UniRef50_A7SIT3 Cluster: Predicted protein; n=1; Nematostella ve... 150 2e-35
UniRef50_P27800 Cluster: Aldehyde reductase 1; n=18; root|Rep: A... 150 2e-35
UniRef50_UPI0000E4A7CE Cluster: PREDICTED: similar to LOC553452 ... 149 4e-35
UniRef50_Q2V420 Cluster: Uncharacterized protein At2g37770.1; n=... 149 4e-35
UniRef50_Q0PGJ6 Cluster: Aldo-keto reductase; n=32; Magnoliophyt... 149 4e-35
UniRef50_UPI00015B56A3 Cluster: PREDICTED: similar to aldo-keto ... 148 7e-35
UniRef50_Q17DN1 Cluster: Aldo-keto reductase; n=1; Aedes aegypti... 115 8e-35
UniRef50_Q10494 Cluster: Probable oxidoreductase C26F1.07; n=2; ... 147 1e-34
UniRef50_Q96UH3 Cluster: Aldehyde reductase; n=13; Pezizomycotin... 146 3e-34
UniRef50_A4RQH8 Cluster: Predicted protein; n=2; Ostreococcus|Re... 143 3e-33
UniRef50_Q8VC28 Cluster: Aldo-keto reductase family 1 member C13... 142 4e-33
UniRef50_A3U9Y0 Cluster: Aldehyde reductase; n=5; Bacteroidetes|... 142 5e-33
UniRef50_A2R6Z3 Cluster: Catalytic activity: an alcohol + NADP(+... 141 8e-33
UniRef50_Q5BKE9 Cluster: LOC594893 protein; n=5; Xenopus tropica... 140 1e-32
UniRef50_A2QVE5 Cluster: Similarity: shows similarity to several... 139 3e-32
UniRef50_P51857 Cluster: 3-oxo-5-beta-steroid 4-dehydrogenase (E... 138 8e-32
UniRef50_UPI0000498F1F Cluster: oxidoreductase, aldo/keto reduct... 137 1e-31
UniRef50_UPI0000E45E29 Cluster: PREDICTED: similar to aldose red... 136 3e-31
UniRef50_Q0IBY6 Cluster: Alcohol dehydrogenase; n=2; Chroococcal... 136 4e-31
UniRef50_Q2UGR1 Cluster: Aldo/keto reductase family proteins; n=... 135 7e-31
UniRef50_P38715 Cluster: NADPH-dependent aldose reductase GRE3; ... 135 7e-31
UniRef50_A2FPE2 Cluster: Oxidoreductase, aldo/keto reductase fam... 134 9e-31
UniRef50_Q1YPE5 Cluster: Aldehyde reductase; n=7; Bacteria|Rep: ... 133 2e-30
UniRef50_A2EYY6 Cluster: Oxidoreductase, aldo/keto reductase fam... 133 2e-30
UniRef50_Q1IN88 Cluster: Aldehyde reductase; n=5; Bacteria|Rep: ... 133 3e-30
UniRef50_Q9Y020 Cluster: 3-dehydroecdysone 3beta-reductase precu... 133 3e-30
UniRef50_Q55FL3 Cluster: Aldo-keto reductase; n=2; Dictyostelium... 132 4e-30
UniRef50_Q5T2L2 Cluster: Aldo-keto reductase family 1 member C-l... 132 4e-30
UniRef50_Q1U9L6 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 132 5e-30
UniRef50_Q22352 Cluster: Putative uncharacterized protein T08H10... 130 2e-29
UniRef50_Q8SSK6 Cluster: ALDOSE REDUCTASE; n=1; Encephalitozoon ... 129 3e-29
UniRef50_Q9U2J5 Cluster: Putative uncharacterized protein; n=2; ... 128 6e-29
UniRef50_Q4PAT5 Cluster: Putative uncharacterized protein; n=1; ... 128 1e-28
UniRef50_Q7PLK6 Cluster: CG40064-PA; n=1; Drosophila melanogaste... 127 2e-28
UniRef50_Q5KI95 Cluster: Aldo-keto reductase, putative; n=14; Di... 127 2e-28
UniRef50_A2EHN6 Cluster: Oxidoreductase, aldo/keto reductase fam... 126 2e-28
UniRef50_UPI0000D9A956 Cluster: PREDICTED: similar to aldo-keto ... 125 6e-28
UniRef50_Q4FY75 Cluster: Aldo-keto reductase-like protein; n=5; ... 125 8e-28
UniRef50_Q7ZWA4 Cluster: Zgc:56622; n=6; cellular organisms|Rep:... 124 1e-27
UniRef50_Q9VHX4 Cluster: CG2767-PA; n=4; Endopterygota|Rep: CG27... 124 1e-27
UniRef50_Q7ZA52 Cluster: Aldose reductase; n=6; Pezizomycotina|R... 124 2e-27
UniRef50_UPI000023D0F1 Cluster: hypothetical protein FG03517.1; ... 123 3e-27
UniRef50_A7PNI3 Cluster: Chromosome chr1 scaffold_22, whole geno... 121 9e-27
UniRef50_UPI0000499B0E Cluster: oxidoreductase, aldo/keto reduct... 120 2e-26
UniRef50_Q6TY50 Cluster: Reductase 2; n=10; Magnoliophyta|Rep: R... 119 5e-26
UniRef50_P23901 Cluster: Aldose reductase; n=9; Poaceae|Rep: Ald... 118 7e-26
UniRef50_Q0CLQ2 Cluster: Putative uncharacterized protein; n=1; ... 118 1e-25
UniRef50_A6RKL9 Cluster: Putative uncharacterized protein; n=3; ... 118 1e-25
UniRef50_Q6RZX1 Cluster: Gld1; n=22; Pezizomycotina|Rep: Gld1 - ... 117 2e-25
UniRef50_Q8WRT0 Cluster: 3-dehydrecdysone 3b-reductase; n=1; Tri... 116 3e-25
UniRef50_A5E082 Cluster: GCY protein; n=4; Saccharomycetales|Rep... 116 3e-25
UniRef50_P28475 Cluster: NADP-dependent D-sorbitol-6-phosphate d... 116 3e-25
UniRef50_A1D4E3 Cluster: D-xylose reductase (Xyl1), putative; n=... 116 5e-25
UniRef50_Q6NII7 Cluster: Putative oxidoreductase; n=2; Corynebac... 115 8e-25
UniRef50_Q41399 Cluster: Chalcone reductase; n=4; eudicotyledons... 115 8e-25
UniRef50_P14065 Cluster: Protein GCY; n=13; Saccharomycetales|Re... 114 1e-24
UniRef50_UPI00015B4B22 Cluster: PREDICTED: similar to GA15457-PA... 113 2e-24
UniRef50_Q03PG5 Cluster: Aldo/keto reductase of diketogulonate r... 113 2e-24
UniRef50_P26690 Cluster: NAD(P)H-dependent 6'-deoxychalcone synt... 113 2e-24
UniRef50_Q8F1G4 Cluster: Aldehyde reductase; n=8; Bacteria|Rep: ... 113 3e-24
UniRef50_Q16K66 Cluster: Aldo-keto reductase; n=2; Aedes aegypti... 113 3e-24
UniRef50_Q8J0K1 Cluster: 4-dihydromethyltrisporate dehydrogenase... 113 3e-24
UniRef50_A6ESC0 Cluster: ARA1; n=1; unidentified eubacterium SCB... 111 7e-24
UniRef50_Q6CFG7 Cluster: Yarrowia lipolytica chromosome B of str... 111 7e-24
UniRef50_Q5FK98 Cluster: Oxidoreductase; n=8; Lactobacillales|Re... 111 1e-23
UniRef50_P38115 Cluster: D-arabinose dehydrogenase [NAD(P)+] hea... 111 1e-23
UniRef50_Q88SL1 Cluster: Oxidoreductase; n=51; Lactobacillales|R... 111 1e-23
UniRef50_Q7XY49 Cluster: Mannose 6-phosphate reductase; n=1; Gri... 110 2e-23
UniRef50_Q7R2T6 Cluster: GLP_291_56367_57278; n=1; Giardia lambl... 110 2e-23
UniRef50_Q17G72 Cluster: Aldo-keto reductase; n=9; Endopterygota... 110 2e-23
UniRef50_Q4JX70 Cluster: Putative oxidoreductase; n=1; Corynebac... 110 2e-23
UniRef50_A6W8E7 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 110 2e-23
UniRef50_Q23320 Cluster: Putative uncharacterized protein; n=4; ... 110 2e-23
UniRef50_Q03TW0 Cluster: Aldo/keto reductase of diketogulonate r... 109 3e-23
UniRef50_P22045 Cluster: Probable reductase; n=101; cellular org... 109 4e-23
UniRef50_Q9HGY0 Cluster: Glycerol dehydrogenase; n=8; Saccharomy... 108 9e-23
UniRef50_UPI0000519CC2 Cluster: PREDICTED: similar to CG2767-PA;... 107 2e-22
UniRef50_Q01J82 Cluster: OSIGBa0152K17.5 protein; n=28; Magnolio... 107 2e-22
UniRef50_UPI00015B40FA Cluster: PREDICTED: similar to CG2767-PA;... 107 2e-22
UniRef50_A7CWF9 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: ... 106 3e-22
UniRef50_P82125 Cluster: 1,5-anhydro-D-fructose reductase; n=1; ... 106 3e-22
UniRef50_Q9FJK0 Cluster: Aldose reductase-like protein; n=3; cor... 106 4e-22
UniRef50_Q7PM68 Cluster: ENSANGP00000014386; n=1; Anopheles gamb... 106 4e-22
UniRef50_Q6C2L0 Cluster: Yarrowia lipolytica chromosome F of str... 106 4e-22
UniRef50_A3LTU8 Cluster: D-arabinose dehydrogenase; n=5; Sacchar... 106 4e-22
UniRef50_P06632 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 106 4e-22
UniRef50_A2QL02 Cluster: Putative frameshift; n=1; Aspergillus n... 105 5e-22
UniRef50_Q7N0E4 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 105 7e-22
UniRef50_Q03XK0 Cluster: Aldo/keto reductase of diketogulonate r... 105 7e-22
UniRef50_Q83N50 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 104 1e-21
UniRef50_P70883 Cluster: AkrI; n=1; Butyrivibrio fibrisolvens|Re... 103 2e-21
UniRef50_A7BA05 Cluster: Putative uncharacterized protein; n=1; ... 103 2e-21
UniRef50_A6LZ55 Cluster: 2,5-didehydrogluconate reductase; n=1; ... 103 2e-21
UniRef50_Q4Q5N9 Cluster: Prostaglandin f synthase, putative; n=7... 103 2e-21
UniRef50_Q41E86 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 103 3e-21
UniRef50_Q9ZBW7 Cluster: Putative oxidoreductase; n=2; Actinomyc... 102 5e-21
UniRef50_A5AD50 Cluster: Putative uncharacterized protein; n=3; ... 102 5e-21
UniRef50_Q9X0A2 Cluster: Oxidoreductase, aldo/keto reductase fam... 102 6e-21
UniRef50_Q5HR31 Cluster: Oxidoreductase, aldo/keto reductase fam... 102 6e-21
UniRef50_Q01HB5 Cluster: OSIGBa0136O08-OSIGBa0153H12.9 protein; ... 100 2e-20
UniRef50_Q05KR9 Cluster: Benzil reductase; n=5; Bacillales|Rep: ... 100 2e-20
UniRef50_Q03X85 Cluster: Aldo/keto reductase of diketogulonate r... 100 2e-20
UniRef50_Q7NB44 Cluster: ARA1; n=3; Firmicutes|Rep: ARA1 - Mycop... 99 3e-20
UniRef50_A6WDZ5 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:... 99 3e-20
UniRef50_Q968S3 Cluster: Aldoketoreductase-like protein; n=1; Or... 100 4e-20
UniRef50_Q838E0 Cluster: Oxidoreductase, aldo/keto reductase fam... 99 6e-20
UniRef50_Q9ZUJ6 Cluster: T2K10.1 protein; n=16; core eudicotyled... 99 7e-20
UniRef50_UPI00006CD296 Cluster: oxidoreductase, aldo/keto reduct... 97 2e-19
UniRef50_Q68ST9 Cluster: Reductase AKOR2; n=2; Pleurotus djamor|... 97 2e-19
UniRef50_Q1RFP0 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 97 2e-19
UniRef50_Q4PDR0 Cluster: Putative uncharacterized protein; n=1; ... 97 2e-19
UniRef50_Q8ZI40 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 97 3e-19
UniRef50_Q9A2X8 Cluster: Oxidoreductase, aldo/keto reductase fam... 95 9e-19
UniRef50_Q4P4P1 Cluster: Putative uncharacterized protein; n=1; ... 95 9e-19
UniRef50_UPI00015B4912 Cluster: PREDICTED: similar to aldo-keto ... 95 1e-18
UniRef50_A4FEB9 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 95 1e-18
UniRef50_A0JRJ3 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 95 1e-18
UniRef50_Q8ET73 Cluster: 2,5-diketo-D-gluconate reductase; n=12;... 94 2e-18
UniRef50_A2UAH0 Cluster: Aldo/keto reductase; n=1; Bacillus coag... 94 2e-18
UniRef50_Q7WSY4 Cluster: Putative aldo-keto reductase; n=1; Prop... 93 3e-18
UniRef50_Q89JN4 Cluster: Oxidoreductase; n=8; Rhizobiales|Rep: O... 93 4e-18
UniRef50_Q5FLI5 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: ... 93 4e-18
UniRef50_UPI00015B5BD7 Cluster: PREDICTED: similar to aldo-keto ... 93 5e-18
UniRef50_Q7VG53 Cluster: Aldo-keto reductase; n=28; Bacteria|Rep... 93 5e-18
UniRef50_A6NPD6 Cluster: Putative uncharacterized protein; n=3; ... 93 5e-18
UniRef50_A3UJS6 Cluster: Oxidoreductase; n=3; Alphaproteobacteri... 93 5e-18
UniRef50_Q88TV9 Cluster: Oxidoreductase; n=4; Lactobacillus|Rep:... 92 6e-18
UniRef50_A3VHZ9 Cluster: Oxidoreductase; n=1; Rhodobacterales ba... 92 9e-18
UniRef50_A3VRL4 Cluster: Putative uncharacterized protein; n=1; ... 91 1e-17
UniRef50_A0JRJ6 Cluster: Aldo/keto reductase; n=2; Micrococcinea... 91 1e-17
UniRef50_Q7G764 Cluster: Probable NAD(P)H-dependent oxidoreducta... 91 1e-17
UniRef50_Q02198 Cluster: Morphine 6-dehydrogenase; n=5; Bacteria... 91 1e-17
UniRef50_Q5XJM7 Cluster: Zgc:101765; n=5; Eumetazoa|Rep: Zgc:101... 91 2e-17
UniRef50_Q1VRG6 Cluster: YvgN; n=1; Psychroflexus torquis ATCC 7... 91 2e-17
UniRef50_A0JX62 Cluster: 2,5-didehydrogluconate reductase; n=9; ... 91 2e-17
UniRef50_A7CUW0 Cluster: 2,5-didehydrogluconate reductase; n=6; ... 90 3e-17
UniRef50_A4YQ04 Cluster: 2,5-diketo-D-gluconate reductase B; n=1... 90 3e-17
UniRef50_Q0SFM4 Cluster: Probable 2,5-didehydrogluconate reducta... 90 3e-17
UniRef50_A7ALH6 Cluster: Putative uncharacterized protein; n=1; ... 90 3e-17
UniRef50_A5ZYE6 Cluster: Putative uncharacterized protein; n=1; ... 90 3e-17
UniRef50_Q7G765 Cluster: Probable NAD(P)H-dependent oxidoreducta... 90 3e-17
UniRef50_UPI00006CCCD7 Cluster: oxidoreductase, aldo/keto reduct... 89 5e-17
UniRef50_Q929C8 Cluster: Lin2349 protein; n=12; Listeria|Rep: Li... 89 5e-17
UniRef50_Q15NA5 Cluster: Aldo/keto reductase; n=2; Gammaproteoba... 89 6e-17
UniRef50_Q568D7 Cluster: Zgc:110366; n=7; Euteleostomi|Rep: Zgc:... 89 8e-17
UniRef50_Q4PHK0 Cluster: Putative uncharacterized protein; n=1; ... 89 8e-17
UniRef50_Q5UX52 Cluster: Oxidoreductase aldo/keto reductase fami... 89 8e-17
UniRef50_Q5BLA6 Cluster: Zgc:110782; n=2; Danio rerio|Rep: Zgc:1... 88 1e-16
UniRef50_Q4V008 Cluster: Oxidoreductase; n=4; Proteobacteria|Rep... 88 1e-16
UniRef50_Q14LU6 Cluster: Putative aldo/keto reductase oxidoreduc... 88 1e-16
UniRef50_Q18483 Cluster: Putative uncharacterized protein; n=2; ... 88 1e-16
UniRef50_Q5B034 Cluster: Putative uncharacterized protein; n=1; ... 88 1e-16
UniRef50_Q2U219 Cluster: Aldo/keto reductase family proteins; n=... 88 1e-16
UniRef50_Q5TNP1 Cluster: ENSANGP00000029046; n=2; Culicidae|Rep:... 88 1e-16
UniRef50_Q24C22 Cluster: Oxidoreductase, aldo/keto reductase fam... 88 1e-16
UniRef50_P47137 Cluster: Probable oxidoreductase YJR096W; n=8; S... 87 2e-16
UniRef50_A5PDA8 Cluster: Putative oxidoreductase protein; n=1; E... 87 2e-16
UniRef50_A7P424 Cluster: Chromosome chr1 scaffold_5, whole genom... 87 2e-16
UniRef50_UPI00005A2CCB Cluster: PREDICTED: similar to Aldose red... 87 3e-16
UniRef50_Q28P63 Cluster: Aldo/keto reductase; n=4; Rhodobacterac... 87 3e-16
UniRef50_Q3E9M9 Cluster: Uncharacterized protein At5g01670.2; n=... 87 3e-16
UniRef50_A2QB88 Cluster: Contig An01c0460, complete genome. prec... 87 3e-16
UniRef50_Q1Q8W8 Cluster: Aldo/keto reductase; n=1; Psychrobacter... 86 4e-16
UniRef50_Q927P9 Cluster: Lin2739 protein; n=12; Bacteria|Rep: Li... 86 6e-16
UniRef50_Q11BF8 Cluster: Aldo/keto reductase; n=12; Bacteria|Rep... 86 6e-16
UniRef50_Q043M4 Cluster: Aldo/keto reductase of diketogulonate r... 86 6e-16
UniRef50_Q8ZH36 Cluster: 2,5-diketo-D-gluconic acid reductase B;... 85 7e-16
UniRef50_Q7VHE1 Cluster: Putative uncharacterized protein; n=1; ... 85 1e-15
UniRef50_A5VK30 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 85 1e-15
UniRef50_A3C1Z7 Cluster: Putative uncharacterized protein; n=2; ... 85 1e-15
UniRef50_Q54NR2 Cluster: Aldo-keto reductase; n=3; Dictyostelium... 84 2e-15
UniRef50_Q17568 Cluster: Putative uncharacterized protein; n=1; ... 84 2e-15
UniRef50_O13848 Cluster: NADH/NADPH dependent indole-3-acetaldeh... 84 2e-15
UniRef50_Q890A0 Cluster: Oxidoreductase; n=6; Lactobacillales|Re... 84 2e-15
UniRef50_Q5FT75 Cluster: Putative 2,5-diketo-D-gluconic acid red... 84 2e-15
UniRef50_Q5FKI1 Cluster: Reductase-dehydrogenase; n=1; Lactobaci... 84 2e-15
UniRef50_Q572D2 Cluster: Aldo-keto reductase, putative; n=1; Phy... 83 3e-15
UniRef50_UPI000155CAC7 Cluster: PREDICTED: hypothetical protein;... 83 4e-15
UniRef50_Q9X265 Cluster: Oxidoreductase, aldo/keto reductase fam... 83 4e-15
UniRef50_A1UEC5 Cluster: 2,5-didehydrogluconate reductase; n=20;... 83 4e-15
UniRef50_A0L1A2 Cluster: Aldo/keto reductase; n=8; Gammaproteoba... 83 4e-15
UniRef50_Q8Y463 Cluster: Lmo2592 protein; n=40; Bacteria|Rep: Lm... 83 5e-15
UniRef50_Q5V663 Cluster: Aldehyde reductase; n=6; Halobacteriace... 83 5e-15
UniRef50_Q235V6 Cluster: Oxidoreductase, aldo/keto reductase fam... 82 9e-15
UniRef50_P91997 Cluster: Putative uncharacterized protein; n=4; ... 82 9e-15
UniRef50_Q5KD52 Cluster: Oxidoreductase, putative; n=1; Filobasi... 82 9e-15
UniRef50_Q4WUF7 Cluster: Aldo-keto reductase, putative; n=3; Pez... 82 9e-15
UniRef50_Q4WP69 Cluster: Aldehyde reductase, putative; n=1; Aspe... 82 9e-15
UniRef50_A6VNW9 Cluster: Aldo/keto reductase precursor; n=1; Act... 81 2e-14
UniRef50_UPI0000DB6EE9 Cluster: PREDICTED: similar to C35D10.6; ... 81 2e-14
UniRef50_A0AWM8 Cluster: Aldo/keto reductase; n=4; Actinomycetal... 80 3e-14
UniRef50_Q5FK99 Cluster: Oxidoreductase aldo-keto reductase fami... 80 4e-14
UniRef50_Q1M4Z6 Cluster: Putative aldo-keto reductase/oxidase; n... 80 4e-14
UniRef50_Q5UYI9 Cluster: Oxidoreductase; n=1; Haloarcula marismo... 80 4e-14
UniRef50_Q8EVS8 Cluster: Oxidoreductase; n=1; Mycoplasma penetra... 79 5e-14
UniRef50_Q11DV1 Cluster: Aldo/keto reductase; n=10; Alphaproteob... 79 5e-14
UniRef50_Q6CEJ0 Cluster: Yarrowia lipolytica chromosome B of str... 79 5e-14
UniRef50_A3WP89 Cluster: Aldo/keto reductase; n=1; Idiomarina ba... 79 6e-14
UniRef50_Q8EVT8 Cluster: Oxidoreductase-aldo/keto reductase fami... 79 9e-14
UniRef50_UPI0000D56CE5 Cluster: PREDICTED: similar to CG6084-PA,... 78 1e-13
UniRef50_Q5V6N9 Cluster: Alcohol dehydrogenase; n=2; Halobacteri... 78 1e-13
UniRef50_Q1DLF1 Cluster: Putative uncharacterized protein; n=1; ... 78 1e-13
UniRef50_UPI00006CA3CB Cluster: oxidoreductase, aldo/keto reduct... 77 3e-13
UniRef50_Q927E1 Cluster: Lin2848 protein; n=13; Listeria|Rep: Li... 77 3e-13
UniRef50_Q8EUH6 Cluster: Oxidoreductase; n=1; Mycoplasma penetra... 77 3e-13
UniRef50_Q3CZS2 Cluster: Oxidoreductase, aldo/keto reductase fam... 77 3e-13
UniRef50_A7D761 Cluster: Aldo/keto reductase; n=2; Halobacteriac... 77 3e-13
UniRef50_Q6F7K7 Cluster: 2,5-diketo-D-gluconate reductase; n=20;... 76 5e-13
UniRef50_P91021 Cluster: Putative uncharacterized protein; n=1; ... 76 5e-13
UniRef50_A7RRF6 Cluster: Predicted protein; n=2; Nematostella ve... 76 5e-13
UniRef50_Q5V398 Cluster: Oxidoreductase aldo/keto reductase fami... 76 6e-13
UniRef50_Q8G7K9 Cluster: Dehydrogenase or reductase protein; n=4... 75 8e-13
UniRef50_A3JU52 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 75 1e-12
UniRef50_A2RMU6 Cluster: Oxidoreductase, aldo/keto reductase fam... 75 1e-12
UniRef50_Q9C1X5 Cluster: Xylose and arabinose reductase; n=1; Sc... 75 1e-12
UniRef50_Q4DJ59 Cluster: Aldo/keto reductase, putative; n=2; Try... 75 1e-12
UniRef50_Q9HM42 Cluster: Alcohol dehydrogenase related protein; ... 75 1e-12
UniRef50_A7BES9 Cluster: Putative uncharacterized protein; n=1; ... 74 2e-12
UniRef50_A3T261 Cluster: Putative uncharacterized protein; n=1; ... 74 2e-12
UniRef50_Q5B5R6 Cluster: Putative uncharacterized protein; n=1; ... 74 2e-12
UniRef50_O14088 Cluster: Xylose and arabinose reductase; n=1; Sc... 74 2e-12
UniRef50_Q7M4N1 Cluster: Dihydrodiol dehydrogenase DD2; n=2; Hom... 71 4e-12
UniRef50_A7D6Q0 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 73 6e-12
UniRef50_Q6WGK4 Cluster: Aldose reductase; n=1; Pristionchus pac... 72 7e-12
UniRef50_Q09632 Cluster: Probable oxidoreductase ZK1290.5; n=2; ... 72 7e-12
UniRef50_Q4Q973 Cluster: Aldo/keto reductase, putative; n=3; Lei... 72 1e-11
UniRef50_Q9P734 Cluster: Related to 2, 5-diketo-D-gluconic acid ... 71 1e-11
UniRef50_A5BF24 Cluster: Putative uncharacterized protein; n=1; ... 71 2e-11
UniRef50_A7D7K7 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 71 2e-11
UniRef50_Q6U5V3 Cluster: Putative uncharacterized protein; n=1; ... 71 2e-11
UniRef50_A6SI80 Cluster: Putative uncharacterized protein; n=1; ... 71 2e-11
UniRef50_A1CAM7 Cluster: Aldo-keto reductase, putative; n=9; Dik... 71 2e-11
UniRef50_Q61U89 Cluster: Putative uncharacterized protein CBG054... 70 3e-11
UniRef50_Q4PE96 Cluster: Putative uncharacterized protein; n=1; ... 70 3e-11
UniRef50_Q0CK00 Cluster: Predicted protein; n=1; Aspergillus ter... 70 3e-11
UniRef50_A6RMS0 Cluster: Putative uncharacterized protein; n=1; ... 70 3e-11
UniRef50_P15339 Cluster: 2,5-diketo-D-gluconic acid reductase B;... 70 3e-11
UniRef50_A4R217 Cluster: Putative uncharacterized protein; n=1; ... 70 4e-11
UniRef50_Q5K8C5 Cluster: Aldo-keto reductase, putative; n=1; Fil... 69 5e-11
UniRef50_A7SGW6 Cluster: Predicted protein; n=1; Nematostella ve... 69 9e-11
UniRef50_Q00XM4 Cluster: Aldo/keto reductase family proteins; n=... 68 1e-10
UniRef50_A6PR52 Cluster: Aldo/keto reductase; n=1; Victivallis v... 68 2e-10
UniRef50_Q59Z55 Cluster: Potential aldo/keto reductase; n=6; Sac... 68 2e-10
UniRef50_A3H9Y8 Cluster: Aldo/keto reductase; n=2; Caldivirga ma... 68 2e-10
UniRef50_Q2BBN7 Cluster: YvgN; n=1; Bacillus sp. NRRL B-14911|Re... 67 2e-10
UniRef50_A5DRJ6 Cluster: Putative uncharacterized protein; n=4; ... 67 2e-10
UniRef50_Q5KKZ8 Cluster: Aldo-keto reductase, putative; n=2; Fil... 67 3e-10
UniRef50_A7LSN6 Cluster: Putative uncharacterized protein; n=3; ... 66 4e-10
UniRef50_Q6CWB9 Cluster: Similarities with sp|Q12458 Saccharomyc... 66 6e-10
UniRef50_Q1PV10 Cluster: Putative uncharacterized protein; n=1; ... 65 9e-10
UniRef50_Q16CS5 Cluster: 2,5-diketo-D-gluconic acid reductase B,... 65 9e-10
UniRef50_Q2CAL9 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 65 1e-09
UniRef50_Q03U37 Cluster: Aldo/keto reductase of diketogulonate r... 65 1e-09
UniRef50_Q0DHN0 Cluster: Os05g0456200 protein; n=2; Oryza sativa... 65 1e-09
UniRef50_Q2H7A8 Cluster: Putative uncharacterized protein; n=1; ... 65 1e-09
UniRef50_Q97UV9 Cluster: Oxidoreductase; n=1; Sulfolobus solfata... 65 1e-09
UniRef50_Q979I4 Cluster: Aldo / keto reductase; n=3; Archaea|Rep... 65 1e-09
UniRef50_Q4JCC1 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 65 1e-09
UniRef50_A7EW94 Cluster: Putative uncharacterized protein; n=1; ... 64 1e-09
UniRef50_Q14LA8 Cluster: Putative aldo/keto reductase oxidoreduc... 64 2e-09
UniRef50_Q5V1M9 Cluster: Oxidoreductase aldo/keto reductase fami... 64 2e-09
UniRef50_P76234 Cluster: Uncharacterized protein yeaE; n=39; Bac... 64 3e-09
UniRef50_Q11B35 Cluster: Aldo/keto reductase; n=1; Mesorhizobium... 63 3e-09
UniRef50_A1RB46 Cluster: 2,5-diketo-D-gluconate reductase; n=1; ... 63 3e-09
UniRef50_A5BYJ4 Cluster: Putative uncharacterized protein; n=1; ... 63 3e-09
UniRef50_Q4WI64 Cluster: Aldehyde reductase, putative; n=22; Pez... 63 3e-09
UniRef50_Q6L139 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 63 3e-09
UniRef50_Q9P6D3 Cluster: Related to aldo-keto reductase YPR1; n=... 63 5e-09
UniRef50_A7D6I8 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 62 6e-09
UniRef50_UPI0001556575 Cluster: PREDICTED: similar to Aldo-keto ... 62 1e-08
UniRef50_Q5FHT2 Cluster: Aldehyde reductase; n=4; Lactobacillus|... 61 1e-08
UniRef50_Q55FL2 Cluster: Putative uncharacterized protein; n=1; ... 61 2e-08
UniRef50_Q97U17 Cluster: Oxidoreductase, aldo/keto reductase fam... 61 2e-08
UniRef50_Q5NLW3 Cluster: Putative oxidoreductase; n=1; Zymomonas... 60 2e-08
UniRef50_Q0GU15 Cluster: ORF28; n=3; Bacteria|Rep: ORF28 - Lacto... 60 3e-08
UniRef50_Q68A33 Cluster: Aldo-keto reductase 1a; n=1; Ciona inte... 60 4e-08
UniRef50_A7TLC4 Cluster: Putative uncharacterized protein; n=1; ... 60 4e-08
UniRef50_A6QVW8 Cluster: Predicted protein; n=1; Ajellomyces cap... 60 4e-08
UniRef50_UPI000038E317 Cluster: hypothetical protein Faci_030017... 59 7e-08
UniRef50_A6R5B4 Cluster: NAD(P)H-dependent D-xylose reductase; n... 59 7e-08
UniRef50_Q4P1G1 Cluster: Putative uncharacterized protein; n=1; ... 58 1e-07
UniRef50_Q9V2P1 Cluster: Myo-inositol degradation; n=5; Archaea|... 58 1e-07
UniRef50_Q64UK5 Cluster: Aldo/keto reductase family oxidoreducta... 58 1e-07
UniRef50_Q21274 Cluster: Putative uncharacterized protein; n=1; ... 58 1e-07
UniRef50_Q75E75 Cluster: ABL209Cp; n=1; Eremothecium gossypii|Re... 58 1e-07
UniRef50_UPI00005F9591 Cluster: COG0656: Aldo/keto reductases, r... 58 2e-07
UniRef50_Q97V56 Cluster: Dehydrogenase; n=8; Thermoprotei|Rep: D... 56 4e-07
UniRef50_UPI000023DF27 Cluster: hypothetical protein FG07276.1; ... 56 5e-07
UniRef50_Q76L37 Cluster: Conjugated polyketone reductase C1; n=3... 56 5e-07
UniRef50_Q76L36 Cluster: Conjugated polyketone reductase C2; n=1... 56 7e-07
UniRef50_A2G4I3 Cluster: Oxidoreductase, aldo/keto reductase fam... 55 9e-07
UniRef50_A4IJ00 Cluster: LOC548351 protein; n=1; Xenopus tropica... 55 1e-06
UniRef50_Q5KCN9 Cluster: Putative uncharacterized protein; n=1; ... 55 1e-06
UniRef50_Q03BE0 Cluster: Aldo/keto reductase family enzyme; n=5;... 54 2e-06
UniRef50_A3LWP0 Cluster: Aldo/keto reductase; n=7; Saccharomycet... 54 2e-06
UniRef50_Q89RG2 Cluster: Aldo/keto reductase; n=11; Bacteria|Rep... 54 2e-06
UniRef50_A2WWZ1 Cluster: Putative uncharacterized protein; n=1; ... 54 2e-06
UniRef50_Q59ZT1 Cluster: Putative uncharacterized protein; n=1; ... 54 3e-06
UniRef50_Q4Q5X1 Cluster: Aldehyde reductase, putative; n=75; cel... 53 5e-06
UniRef50_Q7NK63 Cluster: Gll1617 protein; n=1; Gloeobacter viola... 52 6e-06
UniRef50_Q8YAN3 Cluster: Lmo0084 protein; n=11; Listeria monocyt... 52 1e-05
UniRef50_Q660Z5 Cluster: Aldose reductase, putative; n=3; Borrel... 52 1e-05
UniRef50_A2FJN9 Cluster: Putative uncharacterized protein; n=4; ... 52 1e-05
UniRef50_Q55ML8 Cluster: Putative uncharacterized protein; n=2; ... 52 1e-05
UniRef50_Q2BBT9 Cluster: Probable oxidoreductase protein; n=2; B... 51 1e-05
UniRef50_A7RUA2 Cluster: Predicted protein; n=1; Nematostella ve... 51 1e-05
UniRef50_Q4WF80 Cluster: Glycerol dehydrogenase (GCY1), putative... 51 1e-05
UniRef50_A1S0T5 Cluster: Aldo/keto reductase; n=2; Thermoprotei|... 51 2e-05
UniRef50_Q9X0R5 Cluster: Oxidoreductase, aldo/keto reductase fam... 50 3e-05
UniRef50_Q8PN61 Cluster: Oxidoreductase; n=5; Proteobacteria|Rep... 49 6e-05
UniRef50_A6QXT4 Cluster: Predicted protein; n=1; Ajellomyces cap... 49 8e-05
UniRef50_A6BIJ0 Cluster: Putative uncharacterized protein; n=1; ... 48 1e-04
UniRef50_Q21EY6 Cluster: Aldo/keto reductase; n=1; Saccharophagu... 48 2e-04
UniRef50_Q8DK16 Cluster: Tlr1054 protein; n=6; Cyanobacteria|Rep... 47 2e-04
UniRef50_Q1U6R9 Cluster: Aldo/keto reductase; n=25; Bacilli|Rep:... 47 2e-04
UniRef50_A7HEV1 Cluster: Aldo/keto reductase; n=13; Bacteria|Rep... 47 2e-04
UniRef50_Q9USV2 Cluster: Xylose and arabinose reductase; n=2; Sc... 47 2e-04
UniRef50_Q5BC40 Cluster: Putative uncharacterized protein; n=1; ... 47 3e-04
UniRef50_UPI0000D9C1BD Cluster: PREDICTED: similar to aldo-keto ... 46 4e-04
UniRef50_A6SUJ2 Cluster: Uncharacterized conserved protein; n=2;... 46 4e-04
UniRef50_Q6L0T3 Cluster: Oxidoreductase; n=2; Thermoplasmatales|... 46 4e-04
UniRef50_A0RWV1 Cluster: Oxidoreductase; n=4; Thermoprotei|Rep: ... 40 4e-04
UniRef50_Q013C5 Cluster: Glycerol dehydrogenase, putative; n=2; ... 46 6e-04
UniRef50_UPI00015BB020 Cluster: aldo/keto reductase; n=1; Ignico... 46 7e-04
UniRef50_A3DNU7 Cluster: Aldo/keto reductase; n=3; Desulfurococc... 46 7e-04
UniRef50_Q07551 Cluster: NADPH-dependent alpha-keto amide reduct... 45 0.001
UniRef50_Q03I00 Cluster: Aryl-alcohol dehydrogenase related enzy... 45 0.001
UniRef50_A0QHX8 Cluster: General stress protein 69; n=2; Mycobac... 45 0.001
UniRef50_Q8EUX1 Cluster: Aldo/keto reductase family oxidoreducta... 44 0.002
UniRef50_A3H7G3 Cluster: Aldo/keto reductase; n=2; Caldivirga ma... 44 0.002
UniRef50_UPI0000447325 Cluster: PREDICTED: similar to aldo-keto ... 44 0.002
UniRef50_Q88SS2 Cluster: Oxidoreductase; n=13; Firmicutes|Rep: O... 44 0.002
UniRef50_A6W292 Cluster: Aldo/keto reductase; n=9; Bacteria|Rep:... 44 0.002
UniRef50_A1ZPI5 Cluster: Oxidoreductase; n=1; Microscilla marina... 44 0.002
UniRef50_Q8ZU65 Cluster: Aldo-keto reductase, putative; n=4; The... 44 0.002
UniRef50_A7BLU0 Cluster: Aldo/keto reductase family; n=1; Beggia... 44 0.003
UniRef50_Q18903 Cluster: Putative uncharacterized protein C56G3.... 44 0.003
UniRef50_Q64W37 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 43 0.004
UniRef50_Q93KW0 Cluster: Putative oxidoreductase; n=1; Streptomy... 43 0.004
UniRef50_Q1IQ78 Cluster: Aldo/keto reductase; n=1; Acidobacteria... 43 0.004
UniRef50_Q1FHF4 Cluster: Aldo/keto reductase:4Fe-4S ferredoxin, ... 43 0.004
UniRef50_A0YSM3 Cluster: Probable oxidoreductase; n=1; Lyngbya s... 43 0.004
UniRef50_Q2AI49 Cluster: Aldo/keto reductase; n=1; Halothermothr... 43 0.005
UniRef50_Q03UP2 Cluster: Aryl-alcohol dehydrogenase family enzym... 43 0.005
UniRef50_A6LWU9 Cluster: Aldo/keto reductase; n=3; Clostridium|R... 43 0.005
UniRef50_Q8PVL5 Cluster: Oxidoreductase, ALDO/KETO reductase fam... 43 0.005
UniRef50_Q2NEM6 Cluster: Putative oxidoreductase; n=1; Methanosp... 43 0.005
UniRef50_A7HAM2 Cluster: Aldo/keto reductase; n=9; cellular orga... 42 0.007
UniRef50_A6AKU1 Cluster: Aldo/keto reductase; n=2; Gammaproteoba... 42 0.007
UniRef50_Q03UP0 Cluster: Aryl-alcohol dehydrogenase family enzym... 42 0.009
UniRef50_A2UBC7 Cluster: Aldo/keto reductase; n=3; cellular orga... 42 0.009
UniRef50_A0YC40 Cluster: Putative uncharacterized protein; n=1; ... 42 0.009
UniRef50_A0QWF1 Cluster: Aldo/keto reductase; n=1; Mycobacterium... 42 0.009
UniRef50_P80874 Cluster: General stress protein 69; n=16; cellul... 42 0.009
UniRef50_A1SGJ5 Cluster: Aldo/keto reductase precursor; n=1; Noc... 42 0.012
UniRef50_Q9YBV5 Cluster: Putative uncharacterized protein; n=1; ... 42 0.012
UniRef50_Q88TP1 Cluster: Oxidoreductase; n=3; Bacteria|Rep: Oxid... 41 0.016
UniRef50_Q5ZTU6 Cluster: D-xylose reductase III; n=5; Legionella... 41 0.016
UniRef50_A0LHW7 Cluster: Aldo/keto reductase precursor; n=1; Syn... 41 0.016
UniRef50_Q2JB77 Cluster: Aldo/keto reductase; n=1; Frankia sp. C... 41 0.021
UniRef50_A6X3I0 Cluster: Aldo/keto reductase; n=3; Bacteria|Rep:... 41 0.021
UniRef50_A5GMY9 Cluster: Aldo/keto reductase family protein; n=2... 41 0.021
UniRef50_A1RA11 Cluster: Oxidoreductase, aldo/keto reductase fam... 41 0.021
UniRef50_Q6GIV4 Cluster: Aldo/keto reductase family protein; n=1... 40 0.028
UniRef50_Q41CR8 Cluster: Aldo/keto reductase; n=1; Exiguobacteri... 40 0.028
UniRef50_Q9C2J8 Cluster: Related to D-xylose reductase II, III p... 40 0.028
UniRef50_UPI0000DAE567 Cluster: hypothetical protein Rgryl_01000... 40 0.037
UniRef50_Q4TC86 Cluster: Chromosome undetermined SCAF7044, whole... 40 0.037
UniRef50_Q8UIN0 Cluster: Oxidoreductase; n=3; Alphaproteobacteri... 40 0.037
UniRef50_Q82NW9 Cluster: Putative oxidoreductase; n=3; Streptomy... 40 0.037
UniRef50_Q01Z07 Cluster: Aldo/keto reductase; n=4; cellular orga... 40 0.037
UniRef50_Q08NK7 Cluster: Aldo/keto reductase; n=1; Stigmatella a... 40 0.048
UniRef50_A6WAE5 Cluster: Aldo/keto reductase; n=1; Kineococcus r... 40 0.048
UniRef50_A4M6J9 Cluster: Aldo/keto reductase; n=1; Petrotoga mob... 40 0.048
UniRef50_A0Y7Y8 Cluster: Aldo/keto reductase; n=1; marine gamma ... 40 0.048
UniRef50_A0LJ47 Cluster: Aldo/keto reductase; n=1; Syntrophobact... 40 0.048
UniRef50_Q016B0 Cluster: COG0667: Predicted oxidoreductases; n=4... 40 0.048
UniRef50_Q64UJ6 Cluster: Putative aldo/keto reductase; n=3; Bact... 39 0.064
UniRef50_Q08P32 Cluster: Aldo/keto reductase; n=3; Proteobacteri... 39 0.064
UniRef50_A7B5J6 Cluster: Putative uncharacterized protein; n=1; ... 39 0.064
UniRef50_A5Z5D1 Cluster: Putative uncharacterized protein; n=4; ... 39 0.064
UniRef50_A4QYG8 Cluster: Putative uncharacterized protein; n=1; ... 39 0.064
UniRef50_P46905 Cluster: Uncharacterized oxidoreductase yccK; n=... 39 0.064
UniRef50_Q82JL9 Cluster: Putative oxidoreductase; n=2; Streptomy... 39 0.085
UniRef50_Q391C9 Cluster: Aldo/keto reductase; n=10; Proteobacter... 39 0.085
UniRef50_A7B2Y7 Cluster: Putative uncharacterized protein; n=1; ... 39 0.085
UniRef50_Q5V3K3 Cluster: Oxidoreductase aldo/keto reductase fami... 39 0.085
UniRef50_Q94A68 Cluster: Uncharacterized oxidoreductase At1g0669... 39 0.085
UniRef50_P0A9T5 Cluster: Protein tas; n=88; Bacteria|Rep: Protei... 39 0.085
UniRef50_UPI000023DAA9 Cluster: hypothetical protein FG00321.1; ... 38 0.11
UniRef50_Q8EVP7 Cluster: Putative oxidoreductase; n=3; Bacteria|... 38 0.11
UniRef50_Q4HND9 Cluster: Oxidoreductase, aldo/keto reductase fam... 38 0.11
UniRef50_A5VEK4 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:... 38 0.11
UniRef50_Q2H7Q3 Cluster: Putative uncharacterized protein; n=1; ... 38 0.11
UniRef50_Q97ZZ1 Cluster: Oxidoreductase; n=4; Sulfolobaceae|Rep:... 38 0.11
UniRef50_Q8Y5Q1 Cluster: Lmo2005 protein; n=34; cellular organis... 38 0.15
UniRef50_Q3A7S5 Cluster: Predicted oxidoreductases of the aldo/k... 38 0.15
UniRef50_Q3WEJ4 Cluster: Aldo/keto reductase; n=9; Bacteria|Rep:... 38 0.15
UniRef50_Q04TM6 Cluster: Aryl-alcohol dehydrogenase-related oxid... 38 0.15
UniRef50_A6C2P2 Cluster: Oxidoreductase, aldo/keto reductase fam... 38 0.15
UniRef50_A3EV07 Cluster: Putative oxidoreductase; n=1; Leptospir... 38 0.15
UniRef50_A7PNT1 Cluster: Chromosome chr8 scaffold_23, whole geno... 38 0.15
UniRef50_A3LSR5 Cluster: D-threo-aldose 1-dehydrogenase; n=5; Sa... 38 0.15
UniRef50_UPI00015B403B Cluster: PREDICTED: similar to CG18547-PA... 38 0.20
UniRef50_Q0RGM0 Cluster: Putative aldoketoreductase; n=2; Franki... 38 0.20
UniRef50_Q2NGB6 Cluster: Predicted oxidoreductase; n=1; Methanos... 38 0.20
UniRef50_P49261 Cluster: Rho beta-crystallin; n=1; Lepidodactylu... 38 0.20
UniRef50_Q11BU4 Cluster: Aldo/keto reductase; n=11; Proteobacter... 37 0.26
UniRef50_Q986W6 Cluster: Mlr7180 protein; n=4; Alphaproteobacter... 37 0.34
UniRef50_Q88ZU3 Cluster: Oxidoreductase; n=1; Lactobacillus plan... 37 0.34
UniRef50_Q87SA8 Cluster: Oxidoreductase Tas, aldo/keto reductase... 37 0.34
UniRef50_Q837G5 Cluster: Oxidoreductase, aldo/keto reductase 2 f... 37 0.34
UniRef50_Q2FGN2 Cluster: Oxidoreductase, aldo/keto reductase fam... 37 0.34
UniRef50_Q21F89 Cluster: Aldo/keto reductase; n=1; Saccharophagu... 37 0.34
UniRef50_Q1VSU3 Cluster: Aryl-alcohol dehydrogenase; n=1; Psychr... 37 0.34
UniRef50_A1RAH7 Cluster: Oxidoreductase, aldo/keto reductase fam... 37 0.34
UniRef50_A0K1H5 Cluster: Aldo/keto reductase; n=6; Actinomycetal... 37 0.34
UniRef50_A6SJ74 Cluster: Putative uncharacterized protein; n=1; ... 37 0.34
UniRef50_A6S357 Cluster: Putative uncharacterized protein; n=2; ... 37 0.34
UniRef50_A4EK59 Cluster: Putative oxidoreductase protein; n=1; R... 36 0.45
UniRef50_A7D5V2 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 36 0.45
UniRef50_A7D278 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 36 0.45
UniRef50_A3H9H5 Cluster: Aldo/keto reductase; n=2; Archaea|Rep: ... 36 0.45
UniRef50_Q97RL3 Cluster: Oxidoreductase, aldo/keto reductase fam... 36 0.60
UniRef50_Q11KU9 Cluster: Twin-arginine translocation pathway sig... 36 0.60
UniRef50_A6VX84 Cluster: Aldo/keto reductase; n=4; Gammaproteoba... 36 0.60
UniRef50_A1ZSV4 Cluster: Oxidoreductase, aldo/keto reductase fam... 36 0.60
UniRef50_Q5AQH3 Cluster: Putative uncharacterized protein; n=1; ... 36 0.60
UniRef50_Q2JHT1 Cluster: Aldo/keto reductase Tas; n=25; cellular... 36 0.79
UniRef50_Q97UJ7 Cluster: Oxidoreductase; n=4; Archaea|Rep: Oxido... 36 0.79
UniRef50_Q14722 Cluster: Voltage-gated potassium channel subunit... 36 0.79
UniRef50_Q2J8X9 Cluster: Aldo/keto reductase; n=3; Frankia|Rep: ... 35 1.0
UniRef50_A6W906 Cluster: Putative uncharacterized protein; n=1; ... 35 1.0
UniRef50_A1GCG3 Cluster: Aldo/keto reductase; n=3; Bacteria|Rep:... 35 1.0
UniRef50_A0ZMD5 Cluster: Tas; n=1; Nodularia spumigena CCY 9414|... 35 1.0
UniRef50_Q97UG6 Cluster: Oxidoreductase; n=5; Archaea|Rep: Oxido... 35 1.0
UniRef50_P49249 Cluster: IN2-2 protein; n=6; Magnoliophyta|Rep: ... 35 1.0
UniRef50_Q8R6G2 Cluster: Oxidoreductase; n=1; Fusobacterium nucl... 35 1.4
UniRef50_Q6AMQ0 Cluster: Related to flavoprotein; n=4; Deltaprot... 35 1.4
UniRef50_Q0RGG9 Cluster: Putative oxidoreductase; n=1; Frankia a... 35 1.4
UniRef50_Q034L5 Cluster: Aryl-alcohol dehydrogenase related enzy... 35 1.4
UniRef50_A5FGY2 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:... 35 1.4
UniRef50_A5EHC7 Cluster: Putative oxidoreductase; n=2; Bradyrhiz... 35 1.4
UniRef50_A3TNI0 Cluster: Oxidoreductase, aldo/keto reductase fam... 35 1.4
UniRef50_Q4D2F6 Cluster: Putative uncharacterized protein; n=1; ... 35 1.4
UniRef50_A7DS16 Cluster: Aldo/keto reductase; n=1; Candidatus Ni... 35 1.4
UniRef50_Q01102 Cluster: P-selectin precursor; n=26; Eutheria|Re... 35 1.4
UniRef50_Q3ZWR6 Cluster: Oxidoreductase, aldo reductase; n=3; De... 34 1.8
UniRef50_Q3VQY1 Cluster: Aldo/keto reductase; n=1; Prosthecochlo... 34 1.8
UniRef50_Q0BAM8 Cluster: Aldo/keto reductase; n=1; Burkholderia ... 34 1.8
UniRef50_Q6Z2C3 Cluster: Putative uncharacterized protein OJ1034... 34 1.8
UniRef50_Q5KKC5 Cluster: Putative uncharacterized protein; n=2; ... 34 1.8
UniRef50_Q0U5W4 Cluster: Putative uncharacterized protein; n=1; ... 34 1.8
UniRef50_O59826 Cluster: Potassium channel subunit; n=9; cellula... 34 1.8
UniRef50_Q8TTK4 Cluster: Aldo/keto reductase; n=28; cellular org... 34 1.8
UniRef50_Q7UZ40 Cluster: Putative oxidoreductase-possibly Aldo/k... 34 2.4
UniRef50_Q482D3 Cluster: Sulfatase family protein; n=2; Gammapro... 34 2.4
UniRef50_Q2SL81 Cluster: Predicted oxidoreductase; n=10; Bacteri... 34 2.4
UniRef50_A7LW87 Cluster: Putative uncharacterized protein; n=1; ... 34 2.4
UniRef50_A7T149 Cluster: Predicted protein; n=1; Nematostella ve... 34 2.4
UniRef50_P76187 Cluster: Oxidoreductase ydhF; n=51; Gammaproteob... 34 2.4
UniRef50_Q98JS9 Cluster: Aldo/keto reductase; n=39; Bacteria|Rep... 33 3.2
UniRef50_Q4V2F2 Cluster: Putative uncharacterized protein; n=3; ... 33 3.2
UniRef50_Q2J869 Cluster: Tetratricopeptide TPR_2; n=1; Frankia s... 33 3.2
UniRef50_P73573 Cluster: Sll0867 protein; n=15; Bacteria|Rep: Sl... 33 3.2
UniRef50_A6VXU3 Cluster: Aldo/keto reductase; n=14; Proteobacter... 33 3.2
UniRef50_A7PU13 Cluster: Chromosome chr7 scaffold_31, whole geno... 33 3.2
UniRef50_Q7Q0Y6 Cluster: ENSANGP00000006086; n=7; Coelomata|Rep:... 33 3.2
UniRef50_Q6BZU5 Cluster: Similar to sp|Q04212 Saccharomyces cere... 33 3.2
UniRef50_Q5ASJ7 Cluster: Putative uncharacterized protein; n=1; ... 33 3.2
UniRef50_P40690 Cluster: Aldo-keto reductase; n=4; Piroplasmida|... 33 3.2
UniRef50_UPI0001554EC3 Cluster: PREDICTED: hypothetical protein,... 33 4.2
UniRef50_UPI0000E801E4 Cluster: PREDICTED: hypothetical protein;... 33 4.2
UniRef50_Q4T380 Cluster: Chromosome 21 SCAF10109, whole genome s... 33 4.2
UniRef50_Q97KZ9 Cluster: Fe-S oxidoreductase; n=6; cellular orga... 33 4.2
UniRef50_Q7VG62 Cluster: Aldo-keto reductase; n=2; Helicobacter|... 33 4.2
UniRef50_Q31SB1 Cluster: Putative uncharacterized protein; n=2; ... 33 4.2
>UniRef50_Q7PCV3 Cluster: ENSANGP00000031808; n=9;
Endopterygota|Rep: ENSANGP00000031808 - Anopheles
gambiae str. PEST
Length = 316
Score = 217 bits (529), Expect = 2e-55
Identities = 101/152 (66%), Positives = 110/152 (72%), Gaps = 1/152 (0%)
Frame = +1
Query: 76 VPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 255
VP F N P+ GLGTW S PG+V QAVKDAID+GYRHIDCA+VY NE EVGE I +
Sbjct: 6 VPNAIFKNGNSIPMFGLGTWNSPPGQVAQAVKDAIDVGYRHIDCAHVYQNEHEVGEGIAA 65
Query: 256 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGS 435
KI EGVV REDLF+TSKLWNTFHRPDLV GA + TL NL + YLDLYLIHWP Y+E
Sbjct: 66 KIAEGVVKREDLFVTSKLWNTFHRPDLVEGACKTTLQNLKLDYLDLYLIHWPVGYQEGTE 125
Query: 436 LFPTDQSGK-IQFSDVDYVDTWKAMEPLVKEG 528
LFP GK FSD DYVDTW ME LV G
Sbjct: 126 LFPMGPDGKTFLFSDADYVDTWPEMEKLVDAG 157
>UniRef50_Q2LZ66 Cluster: GA19341-PA; n=2; Endopterygota|Rep:
GA19341-PA - Drosophila pseudoobscura (Fruit fly)
Length = 315
Score = 208 bits (508), Expect = 6e-53
Identities = 93/153 (60%), Positives = 115/153 (75%), Gaps = 1/153 (0%)
Frame = +1
Query: 73 SVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAIT 252
S P ++ P++GLGTW+S P V QAVKDAIDIGYRH DCA++YGNE VG AI
Sbjct: 2 STPSFLLSSGRNMPMVGLGTWRSPPEVVAQAVKDAIDIGYRHFDCAHIYGNELHVGVAIR 61
Query: 253 SKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDG 432
KI+EG+VTR++LFITSKLWNTFH+P+LVR A + +L NL + YLDLYL+HWP AYK
Sbjct: 62 EKIQEGLVTRDELFITSKLWNTFHKPELVRAACETSLRNLGIDYLDLYLMHWPMAYKSGD 121
Query: 433 SLFPT-DQSGKIQFSDVDYVDTWKAMEPLVKEG 528
+L+PT +GK F D+DY+DTWKAME LV G
Sbjct: 122 NLYPTCPDTGKAVFEDIDYLDTWKAMEDLVDSG 154
>UniRef50_Q9VTL0 Cluster: CG6083-PA; n=4; Diptera|Rep: CG6083-PA -
Drosophila melanogaster (Fruit fly)
Length = 322
Score = 204 bits (499), Expect = 8e-52
Identities = 94/154 (61%), Positives = 116/154 (75%), Gaps = 2/154 (1%)
Frame = +1
Query: 73 SVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAIT 252
S P +N P+LGLGTW+S P VTQAVKDAIDIGYRH DCA++YGNE +VG A+
Sbjct: 2 STPNFLLSNGKNMPMLGLGTWRSPPEVVTQAVKDAIDIGYRHFDCAHIYGNEAQVGAALR 61
Query: 253 SKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKE-D 429
K+ EGVVTR++LFITSKLWNT H+PDLVR A + ++ NL V+YL+LYL+HWP AYK
Sbjct: 62 EKMDEGVVTRDELFITSKLWNTHHKPDLVRPACETSIRNLGVKYLNLYLMHWPMAYKSGS 121
Query: 430 GSLFPT-DQSGKIQFSDVDYVDTWKAMEPLVKEG 528
+L+PT + K F D+DYVDTW+AME LV EG
Sbjct: 122 DNLYPTCPDTNKAAFEDIDYVDTWRAMENLVDEG 155
>UniRef50_P45376 Cluster: Aldose reductase; n=21; Bilateria|Rep:
Aldose reductase - Mus musculus (Mouse)
Length = 316
Score = 204 bits (499), Expect = 8e-52
Identities = 94/148 (63%), Positives = 109/148 (73%)
Frame = +1
Query: 85 VEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 264
+E NN K P LGLGTWKS PG+VT+AVK AID+GYRHIDCA VY NEKEVG A+ K+K
Sbjct: 5 LELNNGTKMPTLGLGTWKSPPGQVTEAVKVAIDLGYRHIDCAQVYQNEKEVGVALQEKLK 64
Query: 265 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 444
E VV R+DLFI SKLW TFH +V+GA Q+TL +L + YLDLYLIHWP +K FP
Sbjct: 65 EQVVKRQDLFIVSKLWCTFHDKSMVKGAFQKTLSDLQLDYLDLYLIHWPTGFKPGPDYFP 124
Query: 445 TDQSGKIQFSDVDYVDTWKAMEPLVKEG 528
D SG + SD D+VDTW AME LV EG
Sbjct: 125 LDASGNVIPSDTDFVDTWTAMEQLVDEG 152
>UniRef50_P15121 Cluster: Aldose reductase; n=72; Eumetazoa|Rep:
Aldose reductase - Homo sapiens (Human)
Length = 316
Score = 200 bits (487), Expect = 2e-50
Identities = 91/145 (62%), Positives = 108/145 (74%)
Frame = +1
Query: 94 NNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 273
NN K PILGLGTWKS PG+VT+AVK AID+GYRHIDCA+VY NE EVG AI K++E V
Sbjct: 8 NNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQV 67
Query: 274 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQ 453
V RE+LFI SKLW T+H LV+GA Q+TL +L + YLDLYLIHWP +K FP D+
Sbjct: 68 VKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDE 127
Query: 454 SGKIQFSDVDYVDTWKAMEPLVKEG 528
SG + SD + +DTW AME LV EG
Sbjct: 128 SGNVVPSDTNILDTWAAMEELVDEG 152
>UniRef50_UPI00015B56A2 Cluster: PREDICTED: similar to GA10458-PA;
n=2; Nasonia vitripennis|Rep: PREDICTED: similar to
GA10458-PA - Nasonia vitripennis
Length = 569
Score = 187 bits (456), Expect = 1e-46
Identities = 80/151 (52%), Positives = 111/151 (73%)
Frame = +1
Query: 76 VPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 255
VP V FN+ K P++GLGT+ SKPGEV +AVK AI++GYRH+D A+ Y NEKE+G AI
Sbjct: 3 VPTVTFNDGYKMPMIGLGTFLSKPGEVAEAVKYAIEVGYRHVDTAFFYENEKEIGSAIRE 62
Query: 256 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGS 435
KI +G + RED+F+T+KLW H+ D V A +++L+NL Y+DL+L+HWP A+K +
Sbjct: 63 KINDGTIKREDIFVTTKLWCNSHKEDEVVPACKKSLENLGFDYIDLFLVHWPFAFKSGDA 122
Query: 436 LFPTDQSGKIQFSDVDYVDTWKAMEPLVKEG 528
L P D +GKI+FSD DY++TWK ME ++G
Sbjct: 123 LTPRDAAGKIEFSDTDYLETWKGMEECKRQG 153
Score = 113 bits (273), Expect = 2e-24
Identities = 55/114 (48%), Positives = 75/114 (65%), Gaps = 1/114 (0%)
Frame = +1
Query: 190 YRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDN 369
YRHID AY+Y NEK +G AI KIK+G V REDLF+T+KL H+ V A +++L++
Sbjct: 301 YRHIDTAYLYDNEKYIGNAIREKIKDGTVKREDLFVTTKLSYYAHKESEVVPACKQSLND 360
Query: 370 LNVQYLDLYLIHWP-QAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEG 528
L + Y+DLYLIHWP + Y + SGK+ SD DY++TWK ME ++G
Sbjct: 361 LGLDYIDLYLIHWPIRRYFRHNK----NASGKLLLSDTDYLETWKGMEECKRQG 410
>UniRef50_Q8CI22 Cluster: 2310005E10Rik protein; n=30;
Tetrapoda|Rep: 2310005E10Rik protein - Mus musculus
(Mouse)
Length = 316
Score = 186 bits (453), Expect = 3e-46
Identities = 87/149 (58%), Positives = 101/149 (67%)
Frame = +1
Query: 82 FVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 261
FV K PI+GLGTWKS P +V +AVK AID GYRHIDCAYVY NE EVGEAI KI
Sbjct: 4 FVTLLTGAKMPIVGLGTWKSPPAKVREAVKVAIDAGYRHIDCAYVYQNESEVGEAIQEKI 63
Query: 262 KEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLF 441
+E V REDLFI SKLW+TF LV+ A Q TL +L + YLDLYLIHWPQ ++
Sbjct: 64 QEKAVKREDLFIVSKLWSTFFEKSLVKKAFQNTLSDLKLDYLDLYLIHWPQGFQSGNVFL 123
Query: 442 PTDQSGKIQFSDVDYVDTWKAMEPLVKEG 528
PTD G I S ++D W+AME LV +G
Sbjct: 124 PTDDKGSILSSKYTFLDAWEAMEELVDQG 152
>UniRef50_Q9NAI5 Cluster: Putative uncharacterized protein; n=3;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 316
Score = 182 bits (442), Expect = 6e-45
Identities = 80/151 (52%), Positives = 104/151 (68%)
Frame = +1
Query: 76 VPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 255
V ++ N+ P +GLGTW+SKPGEV A+K A+ GYRHIDCA+VY N+KEVGEA+
Sbjct: 2 VQSLKLNSGYSIPAIGLGTWQSKPGEVAAAIKTAVAAGYRHIDCAHVYQNQKEVGEALKE 61
Query: 256 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGS 435
+ EG V RE+LFITSK+WNTFH + L +L + Y+DL LIHWPQ Y E
Sbjct: 62 ILDEGKVKREELFITSKVWNTFHSEAKAHENIDIILSDLQLSYVDLMLIHWPQGYAEGAE 121
Query: 436 LFPTDQSGKIQFSDVDYVDTWKAMEPLVKEG 528
LFP ++GK+++SDVDY++TWKA E K G
Sbjct: 122 LFPAGENGKMRYSDVDYLETWKAFEAAQKAG 152
>UniRef50_P14550 Cluster: Alcohol dehydrogenase [NADP+]; n=44;
Bilateria|Rep: Alcohol dehydrogenase [NADP+] - Homo
sapiens (Human)
Length = 325
Score = 174 bits (423), Expect = 1e-42
Identities = 76/142 (53%), Positives = 103/142 (72%), Gaps = 1/142 (0%)
Frame = +1
Query: 106 KCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEG-VVTR 282
K P++GLGTWKS+PG+V AVK A+ +GYRHIDCA +YGNE E+GEA+ + G V R
Sbjct: 13 KMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVGPGKAVPR 72
Query: 283 EDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGK 462
E+LF+TSKLWNT H P+ V AL++TL +L ++YLDLYL+HWP A++ + FP + G
Sbjct: 73 EELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADGT 132
Query: 463 IQFSDVDYVDTWKAMEPLVKEG 528
I + Y +TWKA+E LV +G
Sbjct: 133 ICYDSTHYKETWKALEALVAKG 154
>UniRef50_Q7QK25 Cluster: ENSANGP00000019775; n=2; Anopheles gambiae
str. PEST|Rep: ENSANGP00000019775 - Anopheles gambiae
str. PEST
Length = 319
Score = 171 bits (415), Expect = 1e-41
Identities = 78/157 (49%), Positives = 108/157 (68%), Gaps = 4/157 (2%)
Frame = +1
Query: 70 SSVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAI 249
+ VP V F+N + P+LG GT+ ++ G+ + VK AID+GYRHID A++Y NE E+G+AI
Sbjct: 3 TQVPTVRFSNGYEIPVLGYGTYLAQKGQCVELVKKAIDLGYRHIDTAFLYENEVEIGQAI 62
Query: 250 TSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKED 429
KI EGV+ RED+F+T+KLWNTFH P V A + + D L++ Y+DL+L+H P +
Sbjct: 63 RDKIAEGVIRREDVFVTTKLWNTFHDPQHVEEAFRRSFDMLDIGYIDLFLMHSPMGVQFS 122
Query: 430 G----SLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEG 528
G + P D +G + FSDVDYV+TWKAME LV G
Sbjct: 123 GYEYADMQPKDAAGNMLFSDVDYVETWKAMEKLVTAG 159
>UniRef50_Q17DN0 Cluster: Aldo-keto reductase; n=5; Culicidae|Rep:
Aldo-keto reductase - Aedes aegypti (Yellowfever
mosquito)
Length = 324
Score = 168 bits (409), Expect = 6e-41
Identities = 83/155 (53%), Positives = 107/155 (69%), Gaps = 4/155 (2%)
Frame = +1
Query: 76 VPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 255
+P V+ NN L+ P +GLGT SK E +AV AID G+RHID AY Y NE VG AI +
Sbjct: 6 IPTVKLNNGLEMPAIGLGTSMSKGDECCKAVMTAIDEGFRHIDTAYNYRNEDVVGRAIRA 65
Query: 256 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDG- 432
KI+EGVVTRE+LF+T+KLWNTFH PD V A ++L++L + Y+DL+LIH P Y+ +G
Sbjct: 66 KIEEGVVTREELFVTTKLWNTFHHPDHVPMAFGKSLEHLGLDYVDLFLIHMPFGYEFNGW 125
Query: 433 ---SLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEG 528
P D +G + SD DYVDTWKAME L++ G
Sbjct: 126 DPEKRTPLDDNGNVLCSDDDYVDTWKAMEKLLESG 160
>UniRef50_A5KSS3 Cluster: Aldehyde reductase; n=1; candidate
division TM7 genomosp. GTL1|Rep: Aldehyde reductase -
candidate division TM7 genomosp. GTL1
Length = 299
Score = 160 bits (389), Expect = 2e-38
Identities = 75/144 (52%), Positives = 96/144 (66%)
Frame = +1
Query: 97 NELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVV 276
N+ P+LG GTW+ G V+ AI GYRHIDCA +YGNEKEVGE I I +GVV
Sbjct: 8 NKQTLPLLGYGTWELPTGTTADLVETAIKAGYRHIDCAMIYGNEKEVGEGIRRTIDQGVV 67
Query: 277 TREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQS 456
REDLF+TSKLWNT H V A ++TL++L + YLDLYLIHW A++ +L P D
Sbjct: 68 KREDLFVTSKLWNTDHAQVDVGVACRKTLNDLGLDYLDLYLIHWGVAFEHGDNLEPLDDD 127
Query: 457 GKIQFSDVDYVDTWKAMEPLVKEG 528
G +FS + +TW+AME LV++G
Sbjct: 128 GVAKFSFISMKETWQAMEELVEQG 151
>UniRef50_Q0VGY1 Cluster: 3-alpha-hydroxysteroid dehydrogenase;
n=13; Tetrapoda|Rep: 3-alpha-hydroxysteroid
dehydrogenase - Xenopus tropicalis (Western clawed frog)
(Silurana tropicalis)
Length = 324
Score = 160 bits (388), Expect = 2e-38
Identities = 71/146 (48%), Positives = 100/146 (68%), Gaps = 3/146 (2%)
Frame = +1
Query: 82 FVEFNNELKCPILGLGTW---KSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAIT 252
+VE N+ K P++G GT+ K + K AID+GYRHIDCA++YGNE+EVG AI
Sbjct: 8 YVELNDGHKMPVIGFGTYAPPKFPKSLAEEGTKVAIDVGYRHIDCAFLYGNEEEVGRAIR 67
Query: 253 SKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDG 432
+KI +G V RED+F T KLW+T H P+ VR AL+++L +L + Y+DL++IH P +K
Sbjct: 68 AKIADGTVKREDVFYTGKLWSTSHTPERVRPALEKSLKDLQLDYMDLFIIHMPMEFKPGD 127
Query: 433 SLFPTDQSGKIQFSDVDYVDTWKAME 510
LFP D++GK + + D DTWKA+E
Sbjct: 128 DLFPADENGKFIYHNTDLRDTWKALE 153
>UniRef50_Q8K023 Cluster: Aldo-keto reductase family 1 member C18;
n=72; Tetrapoda|Rep: Aldo-keto reductase family 1 member
C18 - Mus musculus (Mouse)
Length = 323
Score = 157 bits (382), Expect = 1e-37
Identities = 71/150 (47%), Positives = 104/150 (69%), Gaps = 3/150 (2%)
Frame = +1
Query: 70 SSVPFVEFNNELKCPILGLGTWKSKPG---EVTQAVKDAIDIGYRHIDCAYVYGNEKEVG 240
S + +E N+ P+LG GT+ ++ + ++ K AID+G+ HIDC+++Y NE+E+G
Sbjct: 3 SKIQKIELNDGHSIPVLGFGTYATEEHLKKKSMESTKIAIDVGFCHIDCSHLYQNEEEIG 62
Query: 241 EAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAY 420
+AI SKI++G V RED+F TSKLW+T HRP+LVR +L+ +L LN+ Y+DLYLIH+P +
Sbjct: 63 QAILSKIEDGTVKREDIFYTSKLWSTSHRPELVRPSLENSLRKLNLDYVDLYLIHFPVSL 122
Query: 421 KEDGSLFPTDQSGKIQFSDVDYVDTWKAME 510
K L P D+ G + F VD DTW+AME
Sbjct: 123 KPGNELLPKDEHGNLIFDTVDLCDTWEAME 152
>UniRef50_UPI0000588153 Cluster: PREDICTED: hypothetical protein;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 333
Score = 157 bits (381), Expect = 2e-37
Identities = 69/141 (48%), Positives = 96/141 (68%), Gaps = 2/141 (1%)
Frame = +1
Query: 112 PILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 291
P++GLGTWK K EV A+ A+D GYRH DCA +YGNEKEVG A+ ++ + RED+
Sbjct: 14 PLVGLGTWKLKADEVAGAIGAAVDAGYRHFDCALIYGNEKEVGVALREAMQRLGLKREDV 73
Query: 292 FITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGS--LFPTDQSGKI 465
FIT+K+WNTFH + V +L +L + Y+DLY++HWP ++ G +FP ++G I
Sbjct: 74 FITTKVWNTFHAKEDVAECFNRSLTDLQLDYIDLYIMHWPLGFQNLGPTVMFPRTETGDI 133
Query: 466 QFSDVDYVDTWKAMEPLVKEG 528
+SDV Y++TW AME LVK G
Sbjct: 134 VYSDVHYLETWSAMEDLVKTG 154
>UniRef50_Q2S340 Cluster: Aldehyde reductase; n=10; Bacteria|Rep:
Aldehyde reductase - Salinibacter ruber (strain DSM
13855)
Length = 321
Score = 155 bits (376), Expect = 6e-37
Identities = 71/148 (47%), Positives = 96/148 (64%)
Frame = +1
Query: 85 VEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 264
+ F N + P++GLGTWKS PGEV +AV A++ GYRH+DCA +Y NE EVG A++
Sbjct: 4 ISFENGDEMPMIGLGTWKSPPGEVYEAVTTALEAGYRHVDCAPIYKNETEVGAALSDSFD 63
Query: 265 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 444
G + R+D+++TSKLWN H PD VR AL++TL +L + LDLYLIHWP A + + FP
Sbjct: 64 AGGIRRDDVWVTSKLWNNAHHPDDVRPALEQTLSDLRLDALDLYLIHWPVALQPEVD-FP 122
Query: 445 TDQSGKIQFSDVDYVDTWKAMEPLVKEG 528
+ V +TW AME L K+G
Sbjct: 123 ESPDDFVSPEAVPLTETWAAMEALKKDG 150
>UniRef50_Q96JD6-2 Cluster: Isoform 2 of Q96JD6 ; n=4;
Catarrhini|Rep: Isoform 2 of Q96JD6 - Homo sapiens
(Human)
Length = 263
Score = 154 bits (374), Expect = 1e-36
Identities = 79/158 (50%), Positives = 98/158 (62%), Gaps = 19/158 (12%)
Frame = +1
Query: 112 PILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 291
P +GL +WK+ PG+VT+AVK+AID GYRH DCAY Y NE+EVG I KIKEG V REDL
Sbjct: 5 PAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDL 64
Query: 292 FITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKED--------GSL--- 438
FI +KLW T H+ LV A +++L L + YLDLYLIHWP +K L
Sbjct: 65 FIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSFC 124
Query: 439 --------FPTDQSGKIQFSDVDYVDTWKAMEPLVKEG 528
P D+S + SD D++DTW+AME LV G
Sbjct: 125 LSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITG 162
>UniRef50_Q54B70 Cluster: Aldehyde reductase; n=2; Dictyostelium
discoideum|Rep: Aldehyde reductase - Dictyostelium
discoideum AX4
Length = 297
Score = 154 bits (374), Expect = 1e-36
Identities = 79/151 (52%), Positives = 101/151 (66%), Gaps = 1/151 (0%)
Frame = +1
Query: 79 PFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSK 258
P + ++ K P++G GTWK++ V +AV+ A+D GYRHIDCA VY NEKEVGEA T K
Sbjct: 3 PSFKLSSGHKIPLVGFGTWKAETTLVGKAVEVALDAGYRHIDCAAVYLNEKEVGEAFTKK 62
Query: 259 IK-EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGS 435
E V RED+FITSKLWNTFH+ + VR AL+ TL +L +QYLDLYL+HWP A++ +
Sbjct: 63 FTTEATVKREDVFITSKLWNTFHKKEHVRPALERTLSDLGLQYLDLYLVHWPVAFEYTSN 122
Query: 436 LFPTDQSGKIQFSDVDYVDTWKAMEPLVKEG 528
T SG Q V +TW+ ME LV G
Sbjct: 123 DIQT--SGSTQ-EFVSIRETWEEMEKLVDAG 150
>UniRef50_Q96JD6 Cluster: Aldo-keto reductase family 1 member C-like
protein 2; n=37; Euteleostomi|Rep: Aldo-keto reductase
family 1 member C-like protein 2 - Homo sapiens (Human)
Length = 320
Score = 154 bits (374), Expect = 1e-36
Identities = 79/158 (50%), Positives = 98/158 (62%), Gaps = 19/158 (12%)
Frame = +1
Query: 112 PILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 291
P +GL +WK+ PG+VT+AVK+AID GYRH DCAY Y NE+EVG I KIKEG V REDL
Sbjct: 5 PAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRREDL 64
Query: 292 FITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKED--------GSL--- 438
FI +KLW T H+ LV A +++L L + YLDLYLIHWP +K L
Sbjct: 65 FIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSFC 124
Query: 439 --------FPTDQSGKIQFSDVDYVDTWKAMEPLVKEG 528
P D+S + SD D++DTW+AME LV G
Sbjct: 125 LSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITG 162
>UniRef50_Q7QVQ9 Cluster: GLP_302_44328_45269; n=1; Giardia lamblia
ATCC 50803|Rep: GLP_302_44328_45269 - Giardia lamblia
ATCC 50803
Length = 313
Score = 153 bits (372), Expect = 2e-36
Identities = 72/143 (50%), Positives = 94/143 (65%), Gaps = 4/143 (2%)
Frame = +1
Query: 112 PILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV--VTRE 285
P LG GTW++ P V AV+ A+ GYRHIDCAYVY NE+ +G A K+ + RE
Sbjct: 5 PRLGFGTWQAPPEAVQTAVETALMTGYRHIDCAYVYQNEEAIGRAFGKIFKDASSGIKRE 64
Query: 286 DLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAY--KEDGSLFPTDQSG 459
D++ITSKLWN HRP+LVR ++T+ +L V YLDL+L+HWP A+ + G LFP D G
Sbjct: 65 DVWITSKLWNYNHRPELVREQCKKTMSDLQVDYLDLFLVHWPLAFVRNDVGDLFPKDAEG 124
Query: 460 KIQFSDVDYVDTWKAMEPLVKEG 528
+ V DTW+AME LV+EG
Sbjct: 125 RAMLEKVPLADTWRAMEQLVEEG 147
>UniRef50_Q7JVH6 Cluster: LD24696p; n=2; Sophophora|Rep: LD24696p -
Drosophila melanogaster (Fruit fly)
Length = 311
Score = 152 bits (368), Expect = 6e-36
Identities = 71/150 (47%), Positives = 99/150 (66%)
Frame = +1
Query: 79 PFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSK 258
P + NN + P LGLGTWKS + + + A+D+GYRH+D A+VY NE EVG+AI+ K
Sbjct: 6 PTIRLNNGREMPTLGLGTWKSFESDAYHSTRHALDVGYRHLDTAFVYENEAEVGQAISEK 65
Query: 259 IKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSL 438
I EGVVTRE++F+T+KL H P LV A + +L NL ++Y+DLYL+H P K
Sbjct: 66 IAEGVVTREEVFVTTKLGGIHHDPALVERACRLSLSNLGLEYVDLYLMHMPVGQKFHND- 124
Query: 439 FPTDQSGKIQFSDVDYVDTWKAMEPLVKEG 528
++ G ++ +DVDY+DTW+ ME LV G
Sbjct: 125 --SNVHGTLELTDVDYLDTWREMEKLVDLG 152
>UniRef50_A2QBD7 Cluster: Catalytic activity: an alcohol + NADP(+)
<=> an aldehyde + NADPH; n=4; Trichocomaceae|Rep:
Catalytic activity: an alcohol + NADP(+) <=> an aldehyde
+ NADPH - Aspergillus niger
Length = 323
Score = 151 bits (366), Expect = 1e-35
Identities = 75/154 (48%), Positives = 96/154 (62%)
Frame = +1
Query: 67 MSSVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEA 246
MS N K P +G GTW++KP EV AV+ A+ GYRHIDCA +Y NE EVG
Sbjct: 1 MSLPSHFTINTGAKIPAVGFGTWQAKPLEVENAVEVALREGYRHIDCAAIYRNETEVGNG 60
Query: 247 ITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKE 426
I K GV RE++FIT KLWNT H P+ V AL +TL +L V YLDLYL+HWP A+K
Sbjct: 61 IR---KSGV-PREEIFITGKLWNTKHAPEDVEPALDKTLQDLGVAYLDLYLMHWPCAFKG 116
Query: 427 DGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEG 528
FP + G +++DY+ T++AME L+ G
Sbjct: 117 GDKWFPLNDDGVFDLANIDYITTYRAMEKLLATG 150
>UniRef50_UPI000065D0BD Cluster: Homolog of Homo sapiens "AKR1B1
protein.; n=1; Takifugu rubripes|Rep: Homolog of Homo
sapiens "AKR1B1 protein. - Takifugu rubripes
Length = 330
Score = 151 bits (365), Expect = 1e-35
Identities = 80/175 (45%), Positives = 104/175 (59%), Gaps = 24/175 (13%)
Frame = +1
Query: 76 VPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 255
+P V N P+LGLGTWKS G T+AVK AI GYRHID AYVY NE EVG + +
Sbjct: 2 IPSVTLNTGALMPVLGLGTWKSGKGVTTEAVKVAIGAGYRHIDTAYVYENETEVGAGVQA 61
Query: 256 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQ------- 414
I +GVV RE+LFI SKLW TFH P LVRGA ++TL +LN+ Y+DLYL+H+P
Sbjct: 62 MIDQGVVKREELFIVSKLWCTFHTPSLVRGACEKTLSSLNLDYVDLYLMHFPMGALSATL 121
Query: 415 -----------AYKEDGSL------FPTDQSGKIQFSDVDYVDTWKAMEPLVKEG 528
+++ L FP D+ ++ ++DTW+AME LV +G
Sbjct: 122 DLTSLTDVIPTVFRDFSPLQPGEDPFPLDEHNQLICDGTSFLDTWEAMEELVDDG 176
>UniRef50_A7SIT3 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 323
Score = 150 bits (364), Expect = 2e-35
Identities = 74/149 (49%), Positives = 96/149 (64%)
Frame = +1
Query: 82 FVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 261
F + N P + LGTW+S EV AV+ AI++GYRHIDCA +YGNE E+GEA++ +
Sbjct: 7 FCKLNTGASIPAMALGTWQSSKEEVGNAVRLAIELGYRHIDCAEIYGNEGEIGEALSEVL 66
Query: 262 KEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLF 441
EG V RE+LF+TSKLW H PD V A Q TL NL + YLDLYLIH P A+K+ L
Sbjct: 67 TEGKVKREELFVTSKLWCDSHHPDDVLPACQATLKNLQLDYLDLYLIHIPVAFKKGVRLP 126
Query: 442 PTDQSGKIQFSDVDYVDTWKAMEPLVKEG 528
+ G I ++ +TW+AME LV +G
Sbjct: 127 HSIAEGIIGYTPEGVQNTWQAMEGLVAKG 155
>UniRef50_P27800 Cluster: Aldehyde reductase 1; n=18; root|Rep:
Aldehyde reductase 1 - Sporobolomyces salmonicolor
Length = 323
Score = 150 bits (364), Expect = 2e-35
Identities = 77/150 (51%), Positives = 96/150 (64%), Gaps = 5/150 (3%)
Frame = +1
Query: 94 NNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 273
N ++G GTW++ PGEV Q VK AI+ GYRH+D A VY N+ EVG AI KE
Sbjct: 8 NTGASLELVGYGTWQAAPGEVGQGVKVAIETGYRHLDLAKVYSNQPEVGAAI----KEAG 63
Query: 274 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDG----SLF 441
V REDLFITSKLWN HRP+ V AL +TL L ++YLDLYLIHWP A+ +G +LF
Sbjct: 64 VKREDLFITSKLWNNSHRPEQVEPALDDTLKELGLEYLDLYLIHWPVAFPPEGDITQNLF 123
Query: 442 PTDQSGKIQFS-DVDYVDTWKAMEPLVKEG 528
P +++ +V VDTWKAM L+ G
Sbjct: 124 PKANDKEVKLDLEVSLVDTWKAMVKLLDTG 153
>UniRef50_UPI0000E4A7CE Cluster: PREDICTED: similar to LOC553452
protein; n=6; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to LOC553452 protein -
Strongylocentrotus purpuratus
Length = 321
Score = 149 bits (361), Expect = 4e-35
Identities = 71/142 (50%), Positives = 94/142 (66%), Gaps = 1/142 (0%)
Frame = +1
Query: 106 KCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRE 285
K P+LG GTW+ KP EV + ++ AID GYRHID A +YGNEK VG+ I +KI +G + RE
Sbjct: 15 KLPLLGFGTWQIKPEEVGRVIETAIDCGYRHIDEASLYGNEKGVGDGIKAKIDDGTIKRE 74
Query: 286 DLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKI 465
DLF+TSKLW T P V + +++L +L + YLDL+LIH P + FP D +G
Sbjct: 75 DLFVTSKLWVTDSHPSRVEPSCRQSLSDLGLAYLDLFLIHCPTSAVGGKGPFPMDDNGLF 134
Query: 466 QFSD-VDYVDTWKAMEPLVKEG 528
D +DYVDTW+ ME LV +G
Sbjct: 135 IGDDTIDYVDTWRIMESLVDKG 156
>UniRef50_Q2V420 Cluster: Uncharacterized protein At2g37770.1; n=1;
Arabidopsis thaliana|Rep: Uncharacterized protein
At2g37770.1 - Arabidopsis thaliana (Mouse-ear cress)
Length = 283
Score = 149 bits (361), Expect = 4e-35
Identities = 75/156 (48%), Positives = 97/156 (62%)
Frame = +1
Query: 70 SSVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAI 249
+++ F + N K P +GLGTW++ PG V AV A+ IGYRHIDCA +YGNEKE+G +
Sbjct: 3 NAITFFKLNTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGAVL 62
Query: 250 TSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKED 429
++ VV REDLFITSKLW T H P V AL TL +L ++Y+DLYLIHWP K+
Sbjct: 63 KKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKK- 121
Query: 430 GSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGSGQ 537
GS+ ++ VD TWKAME L G +
Sbjct: 122 GSVGIKPEN----LLPVDIPSTWKAMEALYDSGKAR 153
>UniRef50_Q0PGJ6 Cluster: Aldo-keto reductase; n=32;
Magnoliophyta|Rep: Aldo-keto reductase - Arabidopsis
thaliana (Mouse-ear cress)
Length = 315
Score = 149 bits (361), Expect = 4e-35
Identities = 75/156 (48%), Positives = 97/156 (62%)
Frame = +1
Query: 70 SSVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAI 249
+++ F + N K P +GLGTW++ PG V AV A+ IGYRHIDCA +YGNEKE+G +
Sbjct: 3 NAITFFKLNTGAKFPSVGLGTWQASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGAVL 62
Query: 250 TSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKED 429
++ VV REDLFITSKLW T H P V AL TL +L ++Y+DLYLIHWP K+
Sbjct: 63 KKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIKK- 121
Query: 430 GSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEGSGQ 537
GS+ ++ VD TWKAME L G +
Sbjct: 122 GSVGIKPEN----LLPVDIPSTWKAMEALYDSGKAR 153
>UniRef50_UPI00015B56A3 Cluster: PREDICTED: similar to aldo-keto
reductase; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to aldo-keto reductase - Nasonia vitripennis
Length = 321
Score = 148 bits (359), Expect = 7e-35
Identities = 68/143 (47%), Positives = 91/143 (63%), Gaps = 2/143 (1%)
Frame = +1
Query: 106 KCPILGLGTWK--SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVT 279
K P+LGLGTW+ + P EV AVK AID GYRH DCA YGNE E+G+AI KI +GVV
Sbjct: 15 KVPVLGLGTWQGGNDPDEVENAVKLAIDAGYRHFDCASFYGNEAEIGKAIQEKIDQGVVK 74
Query: 280 REDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSG 459
REDLF+ +K+WN + +LV A + +L L + Y+DLYL+HWP +Y
Sbjct: 75 REDLFVVTKVWNDERKQELVVAACKRSLKKLGLGYIDLYLVHWPFSYPILYQYIVLPTYN 134
Query: 460 KIQFSDVDYVDTWKAMEPLVKEG 528
+ +VDY++TW+ ME +K G
Sbjct: 135 AVTLDEVDYIETWRGMEECIKLG 157
>UniRef50_Q17DN1 Cluster: Aldo-keto reductase; n=1; Aedes
aegypti|Rep: Aldo-keto reductase - Aedes aegypti
(Yellowfever mosquito)
Length = 284
Score = 115 bits (277), Expect(2) = 8e-35
Identities = 54/82 (65%), Positives = 64/82 (78%), Gaps = 2/82 (2%)
Frame = +1
Query: 79 PFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSK 258
P V+ NN L+ P+LGLGTW SK GE +A+K AID GYRHID AY Y NEKEVGEAI +K
Sbjct: 6 PMVKLNNGLEMPVLGLGTWLSKEGEGVEAIKAAIDAGYRHIDTAYFYQNEKEVGEAIRAK 65
Query: 259 IKEGVVTREDLFITSKL--WNT 318
I+EGVV REDLF+T+K W+T
Sbjct: 66 IEEGVVCREDLFVTTKFIDWDT 87
Score = 54.0 bits (124), Expect(2) = 8e-35
Identities = 22/32 (68%), Positives = 26/32 (81%)
Frame = +1
Query: 433 SLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEG 528
+L P D GK+QFSDVDY+DTWKAME L+K G
Sbjct: 89 NLMPYDADGKLQFSDVDYIDTWKAMEKLLKTG 120
>UniRef50_Q10494 Cluster: Probable oxidoreductase C26F1.07; n=2;
Schizosaccharomyces pombe|Rep: Probable oxidoreductase
C26F1.07 - Schizosaccharomyces pombe (Fission yeast)
Length = 321
Score = 147 bits (357), Expect = 1e-34
Identities = 69/141 (48%), Positives = 92/141 (65%)
Frame = +1
Query: 106 KCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRE 285
K P LGLGTW+S+P + AVK A+ GYRHID A +YGNE EVG+ I KE V R+
Sbjct: 23 KIPGLGLGTWRSEPNQTKNAVKTALQYGYRHIDAAAIYGNEDEVGDGI----KESGVPRK 78
Query: 286 DLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKI 465
D+++TSKLW H P+ V AL++TL +L + YLD YLIHWP ++K FP D+ G +
Sbjct: 79 DIWVTSKLWCNAHAPEAVPKALEKTLKDLKLDYLDEYLIHWPVSFKTGEDKFPKDKDGNL 138
Query: 466 QFSDVDYVDTWKAMEPLVKEG 528
+ +TWKAME L++ G
Sbjct: 139 IYEKNPIEETWKAMEKLLETG 159
>UniRef50_Q96UH3 Cluster: Aldehyde reductase; n=13;
Pezizomycotina|Rep: Aldehyde reductase - Coccidioides
posadasii
Length = 314
Score = 146 bits (354), Expect = 3e-34
Identities = 68/139 (48%), Positives = 90/139 (64%)
Frame = +1
Query: 112 PILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 291
P +G GTW+ + + AV A+ GYRHID A VYG EK +G A+ ++R++L
Sbjct: 17 PAIGFGTWQDENAQ-EDAVLTALSAGYRHIDTAAVYGTEKAIGRALA----RSRLSRDEL 71
Query: 292 FITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQF 471
FITSKLWN HRP+ V A+ ++L NL + YLDLYL+HWP A+ +FP D G +
Sbjct: 72 FITSKLWNNKHRPEDVEQAIDQSLKNLEIDYLDLYLMHWPAAFAPGDDMFPKDSQGNSKT 131
Query: 472 SDVDYVDTWKAMEPLVKEG 528
D+DYVDT+KAME LVK G
Sbjct: 132 VDIDYVDTYKAMEKLVKSG 150
>UniRef50_A4RQH8 Cluster: Predicted protein; n=2; Ostreococcus|Rep:
Predicted protein - Ostreococcus lucimarinus CCE9901
Length = 337
Score = 143 bits (346), Expect = 3e-33
Identities = 70/144 (48%), Positives = 89/144 (61%)
Frame = +1
Query: 97 NELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVV 276
N L+ P +GLGTWK++P EV AV+DA+ GY H+DCA Y NE EVGEA+ + G
Sbjct: 12 NGLRIPRVGLGTWKARPNEVRDAVRDALGAGYAHVDCAAAYANESEVGEALREAFERGDA 71
Query: 277 TREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQS 456
RED+F+TSKLWN RP VR AL TL++L V YLDLYLIHWP A+K G++ D
Sbjct: 72 KREDVFVTSKLWNDRRRPRDVREALMTTLNDLGVGYLDLYLIHWPVAWKR-GTVLQPDAE 130
Query: 457 GKIQFSDVDYVDTWKAMEPLVKEG 528
I + W +E V +G
Sbjct: 131 ASI-------AECWSELERCVADG 147
>UniRef50_Q8VC28 Cluster: Aldo-keto reductase family 1 member C13;
n=11; Theria|Rep: Aldo-keto reductase family 1 member
C13 - Mus musculus (Mouse)
Length = 323
Score = 142 bits (345), Expect = 4e-33
Identities = 67/145 (46%), Positives = 98/145 (67%), Gaps = 3/145 (2%)
Frame = +1
Query: 85 VEFNNELKCPILGLGTWKSKPGEVTQAVKDA---IDIGYRHIDCAYVYGNEKEVGEAITS 255
V+ N+ P LG GT+K K +++++ A +D+GYRH+D AY Y E+E+G+AI S
Sbjct: 8 VKLNDGHLIPALGFGTYKPKEVPKSKSLEAACLALDVGYRHVDTAYAYQVEEEIGQAIQS 67
Query: 256 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGS 435
KIK GVV REDLFIT+KLW T RP+LV+ AL+++L L + Y+DLY++H+P K +
Sbjct: 68 KIKAGVVKREDLFITTKLWCTCFRPELVKPALEKSLKKLQLDYVDLYIMHYPVPMKSGDN 127
Query: 436 LFPTDQSGKIQFSDVDYVDTWKAME 510
FP ++ GK VD+ DTW+ +E
Sbjct: 128 DFPVNEQGKSLLDTVDFCDTWERLE 152
>UniRef50_A3U9Y0 Cluster: Aldehyde reductase; n=5;
Bacteroidetes|Rep: Aldehyde reductase - Croceibacter
atlanticus HTCC2559
Length = 316
Score = 142 bits (344), Expect = 5e-33
Identities = 67/148 (45%), Positives = 92/148 (62%)
Frame = +1
Query: 85 VEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 264
++F + P +GLGTWKS P +V +AVK A++ GY+HIDCA Y NE VGEA +
Sbjct: 4 LKFRDGDSIPSIGLGTWKSDPEDVKKAVKIALENGYKHIDCAAAYDNEDAVGEAFKESFE 63
Query: 265 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 444
G V RED+F+TSKLWN H+ + V AL++TL +LN+ YLDLYL+HWP A+K + FP
Sbjct: 64 SGNVKREDIFVTSKLWNNAHKKEDVIPALKKTLKDLNLDYLDLYLMHWPVAFKPSVNGFP 123
Query: 445 TDQSGKIQFSDVDYVDTWKAMEPLVKEG 528
+ + +T AM K+G
Sbjct: 124 EKDEDYLSLEEAPLHETLNAMIEAKKQG 151
>UniRef50_A2R6Z3 Cluster: Catalytic activity: an alcohol + NADP(+)
<=> an aldehyde + NADPH; n=9; Pezizomycotina|Rep:
Catalytic activity: an alcohol + NADP(+) <=> an aldehyde
+ NADPH - Aspergillus niger
Length = 345
Score = 141 bits (342), Expect = 8e-33
Identities = 71/149 (47%), Positives = 94/149 (63%), Gaps = 2/149 (1%)
Frame = +1
Query: 88 EFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKE 267
+ N P +GLGTW+SK EV AV A+ GYRHID A VYGNE+EVG+ + +
Sbjct: 8 KLNTGYDMPAVGLGTWQSKKDEVRDAVIAALKCGYRHIDAAAVYGNEQEVGDGM----RL 63
Query: 268 GVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP- 444
V RE++F+TSKLWNT H P+ V A+ ++L +L YLDLYLIHWP A++ +
Sbjct: 64 SGVPREEIFLTSKLWNTHHHPENVEEAVDKSLADLQTDYLDLYLIHWPVAFRYSTTTIQP 123
Query: 445 -TDQSGKIQFSDVDYVDTWKAMEPLVKEG 528
+Q+G I DV DTW AME LV++G
Sbjct: 124 VNEQTGLIDVVDVPIKDTWAAMEKLVEKG 152
>UniRef50_Q5BKE9 Cluster: LOC594893 protein; n=5; Xenopus
tropicalis|Rep: LOC594893 protein - Xenopus tropicalis
(Western clawed frog) (Silurana tropicalis)
Length = 345
Score = 140 bits (340), Expect = 1e-32
Identities = 64/128 (50%), Positives = 86/128 (67%)
Frame = +1
Query: 127 GTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDLFITSK 306
GT KS +V A K A+D+GYRH+D A++Y +E VG+A K +G + REDLF TSK
Sbjct: 47 GTEKSFIDDVRVATKMALDLGYRHVDGAFLYSSETGVGQAFREKFADGTLKREDLFYTSK 106
Query: 307 LWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDY 486
LWNTFH+P LVR AL++TL L + Y+DLYLIH P ++K LFP ++ G F D
Sbjct: 107 LWNTFHQPHLVRPALEKTLSFLQMDYVDLYLIHMPMSFKPAEELFPKNEDGTCAFDQPDL 166
Query: 487 VDTWKAME 510
+ TW+A+E
Sbjct: 167 LQTWQALE 174
>UniRef50_A2QVE5 Cluster: Similarity: shows similarity to several
dehydrogenases of different specificities; n=4;
Pezizomycotina|Rep: Similarity: shows similarity to
several dehydrogenases of different specificities -
Aspergillus niger
Length = 381
Score = 139 bits (337), Expect = 3e-32
Identities = 70/153 (45%), Positives = 92/153 (60%), Gaps = 7/153 (4%)
Frame = +1
Query: 85 VEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 264
V N+ + P LG GTW+S PG+V AV +A+ GYRH+D A +Y N++EV E I K
Sbjct: 7 VTLNSGAQIPQLGFGTWQSAPGQVGDAVYEALKAGYRHLDLATIYQNQREVAEGIKRAYK 66
Query: 265 EGV-VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLF 441
+ + RED+FITSKLWN+ H P +V AL E L L + YLDLYL+HWP ++ LF
Sbjct: 67 DVPGLKREDIFITSKLWNSQHDPAVVEKALDECLAELELDYLDLYLVHWPVSFTTGSELF 126
Query: 442 PTDQSGKIQFSDV------DYVDTWKAMEPLVK 522
P + ++ DV VDTWKAM L K
Sbjct: 127 PLVKDSSVEGGDVVINDDISIVDTWKAMTQLPK 159
>UniRef50_P51857 Cluster: 3-oxo-5-beta-steroid 4-dehydrogenase (EC
1.3.1.3) (Delta(4)-3- ketosteroid 5-beta-reductase);
n=124; cellular organisms|Rep: 3-oxo-5-beta-steroid
4-dehydrogenase (EC 1.3.1.3) (Delta(4)-3- ketosteroid
5-beta-reductase) - Homo sapiens (Human)
Length = 326
Score = 138 bits (334), Expect = 8e-32
Identities = 70/137 (51%), Positives = 89/137 (64%), Gaps = 4/137 (2%)
Frame = +1
Query: 112 PILGLGTW---KSKP-GEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVT 279
PI+GLGT+ KS P G +VK AID GYRHID AY+Y NE EVGEAI KI EG V
Sbjct: 19 PIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIREKIAEGKVR 78
Query: 280 REDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSG 459
RED+F KLW T H P++VR L+ TL L + Y+DLY+I P A+K ++P D++G
Sbjct: 79 REDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGDEIYPRDENG 138
Query: 460 KIQFSDVDYVDTWKAME 510
K + + TW+AME
Sbjct: 139 KWLYHKSNLCATWEAME 155
>UniRef50_UPI0000498F1F Cluster: oxidoreductase, aldo/keto reductase
family; n=2; Entamoeba histolytica HM-1:IMSS|Rep:
oxidoreductase, aldo/keto reductase family - Entamoeba
histolytica HM-1:IMSS
Length = 305
Score = 137 bits (332), Expect = 1e-31
Identities = 72/149 (48%), Positives = 93/149 (62%)
Frame = +1
Query: 82 FVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 261
+ NN K P LGLGTW S GEV +AV+ AI GYRHIDCA YGNEKEVG+ I S I
Sbjct: 4 YFTLNNGYKIPKLGLGTWMSANGEVGKAVEIAIKNGYRHIDCAKAYGNEKEVGDGIKSAI 63
Query: 262 KEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLF 441
+G V RE+LF+T+KLW+T + VR A E+L L ++YLDLY+IH P L
Sbjct: 64 AKGYVKREELFVTTKLWSTDKHKEDVRPACLESLKKLQLEYLDLYIIHIP--------LT 115
Query: 442 PTDQSGKIQFSDVDYVDTWKAMEPLVKEG 528
++G+ + +TW+ ME LV+EG
Sbjct: 116 ADKKTGEFTEEIIPIEETWREMEKLVEEG 144
>UniRef50_UPI0000E45E29 Cluster: PREDICTED: similar to aldose
reductase; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to aldose reductase -
Strongylocentrotus purpuratus
Length = 274
Score = 136 bits (329), Expect = 3e-31
Identities = 61/97 (62%), Positives = 69/97 (71%)
Frame = +1
Query: 133 WKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDLFITSKLW 312
W SKPG+V AVK AID GYRHIDCA+VYGNE EVG + K VV RED+FITSKLW
Sbjct: 5 WMSKPGQVEAAVKAAIDCGYRHIDCAHVYGNEAEVGAGLKEKFDANVVKREDIFITSKLW 64
Query: 313 NTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYK 423
N H PD V A TL NL + Y+DLYL+HWP AY+
Sbjct: 65 NNKHHPDDVEQACDITLKNLQLSYVDLYLMHWPMAYQ 101
>UniRef50_Q0IBY6 Cluster: Alcohol dehydrogenase; n=2;
Chroococcales|Rep: Alcohol dehydrogenase - Synechococcus
sp. (strain CC9311)
Length = 336
Score = 136 bits (328), Expect = 4e-31
Identities = 65/152 (42%), Positives = 96/152 (63%)
Frame = +1
Query: 73 SVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAIT 252
++ + +N + P+LGLGT KS+ +V ++V++AI IGYRHIDCA +YGNE+EVG+AI
Sbjct: 18 TMQYASLSNGDRMPLLGLGTGKSESRQVYKSVREAIKIGYRHIDCASIYGNEEEVGDAIR 77
Query: 253 SKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDG 432
I+ +TR +L+ITSKLW+ H + V AL ++L NL V YL+LYLIHWP + +
Sbjct: 78 DAIQNHEITRSELWITSKLWSNCHGKNHVEAALSQSLQNLGVDYLNLYLIHWPVGIRPE- 136
Query: 433 SLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEG 528
F + + +TW+AME +G
Sbjct: 137 KTFAESVDDLLTPEESPISETWEAMESTRDKG 168
>UniRef50_Q2UGR1 Cluster: Aldo/keto reductase family proteins; n=2;
Ascomycota|Rep: Aldo/keto reductase family proteins -
Aspergillus oryzae
Length = 323
Score = 135 bits (326), Expect = 7e-31
Identities = 69/147 (46%), Positives = 92/147 (62%), Gaps = 2/147 (1%)
Frame = +1
Query: 88 EFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKE 267
+ N+ P +GLGTW SKP EV AV+ A+ GYRHID A Y NE EVG K+
Sbjct: 8 KLNSGYNIPAIGLGTWLSKPHEVENAVEAALRAGYRHIDAAACYQNENEVGNGW----KK 63
Query: 268 GVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKE-DGSLFP 444
V R+ +FITSKLWNT H P+ V A+ +TL +L YLDLYLIHWP A++ + +L P
Sbjct: 64 SGVPRDQIFITSKLWNTHHHPEHVEEAVNKTLKDLQTDYLDLYLIHWPVAFEHTNETLTP 123
Query: 445 TDQ-SGKIQFSDVDYVDTWKAMEPLVK 522
D + + + ++V DTW A+E LV+
Sbjct: 124 IDPVTKRFRLANVPIADTWAALEKLVE 150
>UniRef50_P38715 Cluster: NADPH-dependent aldose reductase GRE3;
n=39; cellular organisms|Rep: NADPH-dependent aldose
reductase GRE3 - Saccharomyces cerevisiae (Baker's
yeast)
Length = 327
Score = 135 bits (326), Expect = 7e-31
Identities = 73/164 (44%), Positives = 100/164 (60%), Gaps = 10/164 (6%)
Frame = +1
Query: 67 MSSVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEA 246
MSS+ V NN LK P++GLG WK + +AI +GYR D A YGNEKEVGE
Sbjct: 1 MSSL--VTLNNGLKMPLVGLGCWKIDKKVCANQIYEAIKLGYRLFDGACDYGNEKEVGEG 58
Query: 247 ITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYK- 423
I I EG+V+R+D+F+ SKLWN FH PD V+ AL++TL ++ + YLDLY IH+P A+K
Sbjct: 59 IRKAISEGLVSRKDIFVVSKLWNNFHHPDHVKLALKKTLSDMGLDYLDLYYIHFPIAFKY 118
Query: 424 -EDGSLFP--------TDQSGKIQFSDVDYVDTWKAMEPLVKEG 528
+P ++ G I + V +DT++A+E V EG
Sbjct: 119 VPFEEKYPPGFYTGADDEKKGHITEAHVPIIDTYRALEECVDEG 162
>UniRef50_A2FPE2 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=3; Trichomonas vaginalis G3|Rep:
Oxidoreductase, aldo/keto reductase family protein -
Trichomonas vaginalis G3
Length = 309
Score = 134 bits (325), Expect = 9e-31
Identities = 64/137 (46%), Positives = 95/137 (69%), Gaps = 4/137 (2%)
Frame = +1
Query: 112 PILGLGTWKSK-PGEVTQAVKDAI-DIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRE 285
P +GLGT+ ++ P + AV AI D GYRH+DCA Y N++ +GEA++ +G V RE
Sbjct: 5 PSIGLGTFLAEDPAALKAAVHSAIEDSGYRHVDCAAYYKNQEIIGEALSEIFAKGQVKRE 64
Query: 286 DLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAY--KEDGSLFPTDQSG 459
+++ITSK+WNT HRPDL+ +++TL L ++YLDL L+HW A+ +ED P D++G
Sbjct: 65 EVWITSKVWNTKHRPDLLVKDVKKTLKELKLEYLDLVLVHWACAFQSREDDEYLPRDETG 124
Query: 460 KIQFSDVDYVDTWKAME 510
KI ++D ++TWKAME
Sbjct: 125 KIITENIDILETWKAME 141
>UniRef50_Q1YPE5 Cluster: Aldehyde reductase; n=7; Bacteria|Rep:
Aldehyde reductase - gamma proteobacterium HTCC2207
Length = 330
Score = 133 bits (322), Expect = 2e-30
Identities = 69/160 (43%), Positives = 101/160 (63%), Gaps = 9/160 (5%)
Frame = +1
Query: 76 VPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 255
VP V+ +++ P +GLG WK QAV +AI +GYRH+D A YGNE++VGE I
Sbjct: 7 VPGVKVSSK-SMPAVGLGLWKITQDSAAQAVYEAIKVGYRHLDSAADYGNEQQVGEGIAR 65
Query: 256 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA--YKED 429
I EG+ +RE+L+IT+KLWNT+HR + V A + ++D+L + Y+DLYL+H+P A Y +
Sbjct: 66 AIAEGLCSREELWITTKLWNTYHRAEHVEAACRRSMDDLGLDYIDLYLVHFPIALRYVDF 125
Query: 430 GSLFPT----DQSGKIQFSDVDYV---DTWKAMEPLVKEG 528
+P D S + ++D V +TW AME LV+ G
Sbjct: 126 NDRYPAEWIFDHSAEDPAMELDQVPLSETWGAMEQLVESG 165
>UniRef50_A2EYY6 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=9; Trichomonas vaginalis G3|Rep:
Oxidoreductase, aldo/keto reductase family protein -
Trichomonas vaginalis G3
Length = 308
Score = 133 bits (322), Expect = 2e-30
Identities = 72/150 (48%), Positives = 97/150 (64%), Gaps = 9/150 (6%)
Frame = +1
Query: 106 KCPILGLGTWKSKPGE-----VTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEG 270
+ P +GLGTWKS E +T A+K+A GY HIDCA Y NE VG+A+ G
Sbjct: 3 RIPTIGLGTWKSPRSEDLVNAITYAIKEA---GYVHIDCALCYENEDIVGQALQQCWDSG 59
Query: 271 VVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKE---DGSLF 441
+ RE+++ITSKLWNT HR ++V A ++TL +L + YLDLYL+H+P A++ GSL
Sbjct: 60 I-KRENIWITSKLWNTHHRLEIVEEACRKTLKDLRLDYLDLYLMHYPFAFQNTGIGGSLN 118
Query: 442 PTDQSGKIQFSD-VDYVDTWKAMEPLVKEG 528
P D+ G F D V +DTWKAME LV++G
Sbjct: 119 PLDEKGNTIFDDGVSLIDTWKAMEKLVEKG 148
>UniRef50_Q1IN88 Cluster: Aldehyde reductase; n=5; Bacteria|Rep:
Aldehyde reductase - Acidobacteria bacterium (strain
Ellin345)
Length = 313
Score = 133 bits (321), Expect = 3e-30
Identities = 63/140 (45%), Positives = 87/140 (62%), Gaps = 1/140 (0%)
Frame = +1
Query: 112 PILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 291
P LG GT + P A +DA+ G+RH DCA Y NE+EVGEA+ + G + RE++
Sbjct: 21 PALGFGTLIADPALTITATRDALAAGFRHFDCAERYRNEREVGEALRAGRAAGNIAREEI 80
Query: 292 FITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQF 471
F+T+KLWNT HRP+ V A + +LD L + YLDLYLIH P A++ P DQ+G + +
Sbjct: 81 FVTTKLWNTNHRPERVEPAFEASLDRLGLDYLDLYLIHTPFAFQPGDEQDPRDQNGSVIY 140
Query: 472 SD-VDYVDTWKAMEPLVKEG 528
+ V +TW A+E LV G
Sbjct: 141 DEGVTLRETWSALENLVDRG 160
>UniRef50_Q9Y020 Cluster: 3-dehydroecdysone 3beta-reductase
precursor; n=1; Spodoptera littoralis|Rep:
3-dehydroecdysone 3beta-reductase precursor - Spodoptera
littoralis (Egyptian cotton leafworm)
Length = 345
Score = 133 bits (321), Expect = 3e-30
Identities = 69/160 (43%), Positives = 97/160 (60%), Gaps = 9/160 (5%)
Frame = +1
Query: 76 VPFVEFNNELKCPILGLGTW---------KSKPGEVTQAVKDAIDIGYRHIDCAYVYGNE 228
VP ++ N+ + P + LGT+ SK ++ V AID+GYRH D A +Y E
Sbjct: 22 VPMLKMLNDREMPAIALGTYLGFDKGGAVTSKDKQLRNVVMQAIDLGYRHFDTAAIYNTE 81
Query: 229 KEVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHW 408
EVGEAI KI EGV+ RED+F+T+KLWNT H+ + V A++ETL+ + Y+DL+L+HW
Sbjct: 82 AEVGEAIRMKIDEGVIKREDVFLTTKLWNTHHKREQVAVAMKETLNKTGLDYVDLFLMHW 141
Query: 409 PQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEG 528
P A ED S S+ DY++TW+A E +VK G
Sbjct: 142 PIALNEDYS-----------HSNTDYLETWRATEEMVKLG 170
>UniRef50_Q55FL3 Cluster: Aldo-keto reductase; n=2; Dictyostelium
discoideum AX4|Rep: Aldo-keto reductase - Dictyostelium
discoideum AX4
Length = 321
Score = 132 bits (320), Expect = 4e-30
Identities = 68/153 (44%), Positives = 96/153 (62%), Gaps = 6/153 (3%)
Frame = +1
Query: 88 EFNNELKCPILGLGTWKSK-PGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 264
+ N+ + P +GLGT+ S+ PGEV A+ +A+ GYRHID A YGNEK +G ++ K
Sbjct: 18 KLNDGNQIPSIGLGTYYSENPGEVGDAINNALKNGYRHIDGAAFYGNEKVIGNSLKEIFK 77
Query: 265 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 444
EG + RED+F TSKLWN+ H +LV +T+++L + YLDLYLIHWP A++ L
Sbjct: 78 EGEIKREDIFYTSKLWNSCHNSNLVVKHCVKTIEDLGIGYLDLYLIHWPIAFENSNPLGL 137
Query: 445 T-----DQSGKIQFSDVDYVDTWKAMEPLVKEG 528
T DQ+G + V +TW+ ME LV+ G
Sbjct: 138 TIEPLRDQNGNPIIAPVSIRETWQEMEKLVELG 170
>UniRef50_Q5T2L2 Cluster: Aldo-keto reductase family 1 member C-like
protein 1; n=14; Eutheria|Rep: Aldo-keto reductase
family 1 member C-like protein 1 - Homo sapiens (Human)
Length = 302
Score = 132 bits (320), Expect = 4e-30
Identities = 69/152 (45%), Positives = 93/152 (61%), Gaps = 4/152 (2%)
Frame = +1
Query: 85 VEFNNELKCPILGLGTWK---SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 255
V N+ P+LG GT+ + + +A K AID+G+RHID AY+Y NE+EVG+AI
Sbjct: 11 VRLNDGPFMPVLGFGTYAPDHTPKSQAAEATKVAIDVGFRHIDSAYLYQNEEEVGQAIWE 70
Query: 256 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDG- 432
KI +G V RE++F T KLW TF R +LV AL+ +L L Y+DL++IH P A K+ G
Sbjct: 71 KIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPFAMKQPGK 130
Query: 433 SLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEG 528
L P D SG+I V+ DTW+ L K G
Sbjct: 131 ELLPKDASGEIILETVELCDTWELELILNKPG 162
>UniRef50_Q1U9L6 Cluster: 2,5-didehydrogluconate reductase; n=3;
Lactobacillus|Rep: 2,5-didehydrogluconate reductase -
Lactobacillus reuteri 100-23
Length = 288
Score = 132 bits (319), Expect = 5e-30
Identities = 71/145 (48%), Positives = 90/145 (62%)
Frame = +1
Query: 94 NNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 273
NN +K P +G GT+++ QAVK+AI+ GYRHID A VYGNE+ VG+ I K+
Sbjct: 14 NNGVKIPCVGYGTFRTPADVAEQAVKEAIETGYRHIDTAAVYGNEEAVGKGI----KDSG 69
Query: 274 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQ 453
+ REDLF+TSKLWNT + + A QETLD L + YLDLYLIHWP K+ G D
Sbjct: 70 IKREDLFVTSKLWNTNRGYEQTKKAFQETLDRLQMDYLDLYLIHWPANEKQFG-----DD 124
Query: 454 SGKIQFSDVDYVDTWKAMEPLVKEG 528
+ KI +TW+AME L EG
Sbjct: 125 AAKIN------AETWRAMEDLYNEG 143
>UniRef50_Q22352 Cluster: Putative uncharacterized protein T08H10.1;
n=2; Caenorhabditis|Rep: Putative uncharacterized
protein T08H10.1 - Caenorhabditis elegans
Length = 333
Score = 130 bits (314), Expect = 2e-29
Identities = 62/154 (40%), Positives = 99/154 (64%), Gaps = 2/154 (1%)
Frame = +1
Query: 73 SVPFVEFNNELKCPILGLGTWKSKP-GEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAI 249
+V + N + P+ GLGTW+ K E+T A++ A+D GYR ID A++Y NE +G+ +
Sbjct: 2 TVDSIPLNTGAQLPLFGLGTWQVKDEAELTVALRAALDAGYRLIDTAHLYQNEHIIGKVL 61
Query: 250 TSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYK-E 426
I G + RED+F+TSKL T H P+ V ++ L L ++Y+DLYLIH P +K +
Sbjct: 62 HEYISSGKLKREDIFVTSKLPFTAHAPEDVPKCVESQLKALQLEYIDLYLIHCPFPFKHQ 121
Query: 427 DGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEG 528
+GS P ++G++ +++ ++DTW+A+E L KEG
Sbjct: 122 EGSFAPLMENGELAVTEIAHIDTWRALEKLYKEG 155
>UniRef50_Q8SSK6 Cluster: ALDOSE REDUCTASE; n=1; Encephalitozoon
cuniculi|Rep: ALDOSE REDUCTASE - Encephalitozoon
cuniculi
Length = 301
Score = 129 bits (312), Expect = 3e-29
Identities = 66/150 (44%), Positives = 91/150 (60%), Gaps = 3/150 (2%)
Frame = +1
Query: 88 EFNNELKCPILGLGTWKSKPGEVTQ-AVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 264
+ NN + P +GLGTW + V + A+++A+ +GYRHID A++YGNEK +G +
Sbjct: 7 KLNNGKEIPTVGLGTWGMEDEAVLEGAIRNALSLGYRHIDTAFIYGNEKMIGNILKKLFD 66
Query: 265 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAY--KEDGSL 438
EGVV R+DLFITSKLWNTFH L+ +L++L + Y+DLYLIHWP + DG++
Sbjct: 67 EGVVQRKDLFITSKLWNTFH--GCPEDGLRRSLNDLQMDYVDLYLIHWPVTFDPAPDGTV 124
Query: 439 FPTDQSGKIQFSDVDYVDTWKAMEPLVKEG 528
+ K D V WK ME LV G
Sbjct: 125 ESCGK--KYNVGKFDAVGVWKKMEALVDLG 152
>UniRef50_Q9U2J5 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 339
Score = 128 bits (310), Expect = 6e-29
Identities = 59/153 (38%), Positives = 91/153 (59%), Gaps = 5/153 (3%)
Frame = +1
Query: 85 VEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 264
V N+ + P++G GTW+ + V+DA++ GYRHID A + N++EV I K
Sbjct: 7 VTLNSGYEMPVIGYGTWQLPKNLAAERVRDALEAGYRHIDSALSFKNQEEVAAGIKDWCK 66
Query: 265 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKED----- 429
V RE+LF++SK+WNT+H + + E L+ Y+DL +IHWP + ED
Sbjct: 67 IRKVRREELFLSSKIWNTYHSRNRCMQQIDEMLEIFETTYMDLIVIHWPFGWAEDEPPGE 126
Query: 430 GSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEG 528
L+P +GK+++SDVDY++TWKA+E + G
Sbjct: 127 RGLWPRGANGKMRYSDVDYLETWKALEDAHRSG 159
>UniRef50_Q4PAT5 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 700
Score = 128 bits (308), Expect = 1e-28
Identities = 66/150 (44%), Positives = 93/150 (62%), Gaps = 6/150 (4%)
Frame = +1
Query: 97 NELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVV 276
N + P LG GTWK + T AV AI GYRHIDCA+ Y NE +A+ + IK+ V
Sbjct: 16 NGAQIPKLGFGTWKMSKEQATPAVAHAIKTGYRHIDCAWAYRNE----DAVAAGIKKAGV 71
Query: 277 TREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAY-KEDGSLFPTDQ 453
R L++TSKLWN+FH P+ V AL +L +L YLDLYL+HWP A+ GS+ P+ +
Sbjct: 72 PRSQLWLTSKLWNSFHHPEHVEKALDASLKDLGTDYLDLYLMHWPVAFLNSKGSMVPSIR 131
Query: 454 S---GKIQFSDV--DYVDTWKAMEPLVKEG 528
S ++ D+ D++ T++ ME +VK+G
Sbjct: 132 STGGHPVESEDLSRDFMATYRVMEEMVKKG 161
>UniRef50_Q7PLK6 Cluster: CG40064-PA; n=1; Drosophila
melanogaster|Rep: CG40064-PA - Drosophila melanogaster
(Fruit fly)
Length = 361
Score = 127 bits (306), Expect = 2e-28
Identities = 61/128 (47%), Positives = 87/128 (67%), Gaps = 2/128 (1%)
Frame = +1
Query: 151 EVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDLFITSKLWNTFHRP 330
+ + AV AI+ G+RH D AY Y NEKE+GEA+ ++IK G ++RE++F+T+KLWNT H P
Sbjct: 45 QCSAAVHCAIETGFRHFDTAYYYENEKEIGEALRTQIKMGNISRENIFLTTKLWNTHHDP 104
Query: 331 DLVRGALQETLDNLNVQYLDLYLIHWPQAYKE--DGSLFPTDQSGKIQFSDVDYVDTWKA 504
VR ++ L+ L Y+DLYL+H+P YK D L P ++Q ++DY+DTW+A
Sbjct: 105 RDVRRICEKQLELLGFSYIDLYLMHFPVGYKYVCDEILMPM-SGDELQTVEIDYLDTWRA 163
Query: 505 MEPLVKEG 528
ME LVK G
Sbjct: 164 MENLVKLG 171
>UniRef50_Q5KI95 Cluster: Aldo-keto reductase, putative; n=14;
Dikarya|Rep: Aldo-keto reductase, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 353
Score = 127 bits (306), Expect = 2e-28
Identities = 69/160 (43%), Positives = 90/160 (56%), Gaps = 3/160 (1%)
Frame = +1
Query: 67 MSSVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEA 246
MS+ + N P +GLGTW++K GEV QAV A+ GYRHID A Y NE EVG
Sbjct: 33 MSAPTSFKLNTGASIPAIGLGTWQAKAGEVRQAVAHALKAGYRHIDGALCYQNEDEVGLG 92
Query: 247 ITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKE 426
IK+ V R ++F+TSK+W+++H D V L TL +L YLDLYLIHWP
Sbjct: 93 ----IKDSGVPRSEIFLTSKVWSSYH--DRVEECLDTTLKSLQTDYLDLYLIHWPVRLAP 146
Query: 427 DGS--LFPTDQSGKIQFS-DVDYVDTWKAMEPLVKEGSGQ 537
+G+ LFP G D D TW ME ++K+G +
Sbjct: 147 NGTHPLFPVKPDGSRNLDWDWDQAKTWAQMEDVLKKGKAK 186
>UniRef50_A2EHN6 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=10; Trichomonas vaginalis|Rep:
Oxidoreductase, aldo/keto reductase family protein -
Trichomonas vaginalis G3
Length = 312
Score = 126 bits (305), Expect = 2e-28
Identities = 63/148 (42%), Positives = 93/148 (62%), Gaps = 6/148 (4%)
Frame = +1
Query: 103 LKCPILGLGTWKSK-PGEVTQAVKDAID-IGYRHIDCAYVYGNEKEVGEAITSKIKEGVV 276
++ P LG GT+ + P ++ A+ AI+ G RHID A+ Y N+ +GE + +G +
Sbjct: 1 MEIPQLGFGTYLANDPAKLKAALHYAIEECGVRHIDTAFAYYNQNVIGETLKEIFAKGKI 60
Query: 277 TREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYK----EDGSLFP 444
RED+FIT+KLW T HR DLV L E L L + Y+DL+LIH P A+K +DG++ P
Sbjct: 61 KREDMFITTKLWCTHHRKDLVEPELHENLAQLQLSYVDLFLIHQPIAFKSLPAKDGTMMP 120
Query: 445 TDQSGKIQFSDVDYVDTWKAMEPLVKEG 528
D+ GKIQ+ +D ++T+ AME K+G
Sbjct: 121 KDEKGKIQYEQIDILETYHAMEECQKKG 148
>UniRef50_UPI0000D9A956 Cluster: PREDICTED: similar to aldo-keto
reductase family 1, member B10, partial; n=1; Macaca
mulatta|Rep: PREDICTED: similar to aldo-keto reductase
family 1, member B10, partial - Macaca mulatta
Length = 275
Score = 125 bits (302), Expect = 6e-28
Identities = 63/102 (61%), Positives = 72/102 (70%), Gaps = 6/102 (5%)
Frame = +1
Query: 136 KSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDLFITSK--- 306
KS G+V +AVK AID GYRHIDCAYVY NE EVGEAI KI+E V REDLFI SK
Sbjct: 42 KSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEQAVKREDLFIVSKVHM 101
Query: 307 ---LWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYK 423
LW TF LVR A ++TL +L + YLD+YLIHWPQ +K
Sbjct: 102 AHWLWTTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFK 143
>UniRef50_Q4FY75 Cluster: Aldo-keto reductase-like protein; n=5;
Trypanosomatidae|Rep: Aldo-keto reductase-like protein -
Leishmania major strain Friedlin
Length = 372
Score = 125 bits (301), Expect = 8e-28
Identities = 65/146 (44%), Positives = 80/146 (54%), Gaps = 7/146 (4%)
Frame = +1
Query: 112 PILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 291
P LG GT++ E T AV A+ GYRH+DCA YGNE VGEA+ ++ REDL
Sbjct: 31 PQLGFGTYRLPVSEATDAVAFALSCGYRHVDCAKAYGNEAAVGEALAQALRTRCTRREDL 90
Query: 292 FITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA------YKEDGSLFPTDQ 453
F+TSKLW T PD V A + TL L + YLDLYLIHWP + D +P +
Sbjct: 91 FVTSKLWPTDQHPDHVEAACRATLAALQLDYLDLYLIHWPVCMRHTPHWTSDEDRYPRHR 150
Query: 454 SGKIQF-SDVDYVDTWKAMEPLVKEG 528
G + V +DTW AM LV G
Sbjct: 151 DGTPAIDTSVTLLDTWTAMNRLVDRG 176
>UniRef50_Q7ZWA4 Cluster: Zgc:56622; n=6; cellular organisms|Rep:
Zgc:56622 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 289
Score = 124 bits (300), Expect = 1e-27
Identities = 58/124 (46%), Positives = 83/124 (66%), Gaps = 1/124 (0%)
Frame = +1
Query: 160 QAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLV 339
+A + AI GYRHID A+ Y NE +VG AI +KI++G++ R+D+FI SKLW T H P+ +
Sbjct: 4 RACEAAIAAGYRHIDTAFCYRNEVDVGMAIQNKIQQGIIRRQDMFIVSKLWGTHHAPEDI 63
Query: 340 RGALQETLDNLNVQYLDLYLIHWPQAYKEDGS-LFPTDQSGKIQFSDVDYVDTWKAMEPL 516
++L +L + YLD YL+H+P K+ G LFP ++ GKI +D+DYVD W+ ME L
Sbjct: 64 PVCFNKSLSDLQLDYLDQYLVHFPVGLKKVGDELFP-ERDGKILTTDIDYVDVWRGMEAL 122
Query: 517 VKEG 528
G
Sbjct: 123 KATG 126
>UniRef50_Q9VHX4 Cluster: CG2767-PA; n=4; Endopterygota|Rep:
CG2767-PA - Drosophila melanogaster (Fruit fly)
Length = 329
Score = 124 bits (299), Expect = 1e-27
Identities = 62/157 (39%), Positives = 96/157 (61%), Gaps = 3/157 (1%)
Frame = +1
Query: 67 MSSVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEA 246
M + F+ FNN K P++G+GTW++ E+ A+ A++ GYRHID A VYGNEK +G
Sbjct: 1 MVNTKFLTFNNGEKMPVIGIGTWQASDEEIETAIDAALEAGYRHIDTAPVYGNEKAIGRV 60
Query: 247 ITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA--Y 420
+ + G V RE+LFI +K+ +RP V ++++L++L + Y+DLYL+H P
Sbjct: 61 LKRWLDAGKVKREELFIVTKVPPVSNRPHEVEPTIKKSLEDLQLDYVDLYLVHTPFTINI 120
Query: 421 KEDGSLFPTDQSGKIQFS-DVDYVDTWKAMEPLVKEG 528
EDGS F D+ G ++ ++ W AME LV++G
Sbjct: 121 NEDGS-FKLDKEGLMEVDVTTNHAAIWVAMEALVEKG 156
>UniRef50_Q7ZA52 Cluster: Aldose reductase; n=6; Pezizomycotina|Rep:
Aldose reductase - Magnaporthe grisea (Rice blast
fungus) (Pyricularia grisea)
Length = 312
Score = 124 bits (298), Expect = 2e-27
Identities = 67/149 (44%), Positives = 85/149 (57%), Gaps = 4/149 (2%)
Frame = +1
Query: 94 NNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 273
N K P GLGTW+ G + +AV AI GYR ID AYVYGNE+EVG+ I I G+
Sbjct: 9 NTGAKIPAFGLGTWQGDKGVIKEAVLTAIKSGYRLIDGAYVYGNEEEVGQGIREAISSGI 68
Query: 274 VTREDLFITSKLWNTF-HRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGS--LFP 444
V REDLF+ SK W T+ R +L L ++L L + Y+DLYL+HWP +G+ FP
Sbjct: 69 VKREDLFVVSKCWATYTTRCEL---GLDQSLKLLGLDYVDLYLVHWPILMNPEGNDEKFP 125
Query: 445 TDQSGKIQFSDV-DYVDTWKAMEPLVKEG 528
G ++VDTWK ME L G
Sbjct: 126 KHADGSRDIIHTHNHVDTWKLMEKLPATG 154
>UniRef50_UPI000023D0F1 Cluster: hypothetical protein FG03517.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG03517.1 - Gibberella zeae PH-1
Length = 364
Score = 123 bits (296), Expect = 3e-27
Identities = 68/150 (45%), Positives = 95/150 (63%), Gaps = 3/150 (2%)
Frame = +1
Query: 88 EFN-NEL--KCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSK 258
EFN NE P GLGTW + G V AV+ A+ GYRHID A ++ NE EVG+ I
Sbjct: 50 EFNKNETVRDIPAFGLGTWLAGKGVVVPAVEYALKGGYRHIDTALIWRNEDEVGKGI--- 106
Query: 259 IKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSL 438
K V+R+++++T KLWNT HRP+LVR A++ ++ NL V+YLDLYLIH+P A+
Sbjct: 107 -KASGVSRDEIWVTGKLWNTDHRPELVRKAIETSIANLGVEYLDLYLIHYPVAW------ 159
Query: 439 FPTDQSGKIQFSDVDYVDTWKAMEPLVKEG 528
++ + ++ +DTWKAME LV+ G
Sbjct: 160 --VPETRDVD-NNTSLIDTWKAMEELVRAG 186
>UniRef50_A7PNI3 Cluster: Chromosome chr1 scaffold_22, whole genome
shotgun sequence; n=2; Vitis vinifera|Rep: Chromosome
chr1 scaffold_22, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 360
Score = 121 bits (292), Expect = 9e-27
Identities = 62/146 (42%), Positives = 88/146 (60%), Gaps = 1/146 (0%)
Frame = +1
Query: 94 NNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 273
N + K P +GLGTW+S +AVK A+ GYR IDCA++YGNE EVGEA+ G
Sbjct: 15 NTKAKIPAIGLGTWQSGGDLCVEAVKRALSEGYRQIDCAHLYGNEVEVGEALAEAF-NGS 73
Query: 274 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQ 453
+ RED+F+TSKL+ T + + + +++ +L NL V YLDLYL+HWP + P
Sbjct: 74 LKREDVFLTSKLYCTMNSLNKIENSVRVSLKNLGVTYLDLYLMHWPDITAFGDATDPPSN 133
Query: 454 SGKIQFSDVDYV-DTWKAMEPLVKEG 528
SG ++ + WKAME L++ G
Sbjct: 134 SGNDHRQFLNRLKKAWKAMEGLIELG 159
>UniRef50_UPI0000499B0E Cluster: oxidoreductase, aldo/keto reductase
family; n=1; Entamoeba histolytica HM-1:IMSS|Rep:
oxidoreductase, aldo/keto reductase family - Entamoeba
histolytica HM-1:IMSS
Length = 307
Score = 120 bits (290), Expect = 2e-26
Identities = 68/146 (46%), Positives = 88/146 (60%), Gaps = 1/146 (0%)
Frame = +1
Query: 94 NNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGE-AITSKIKEG 270
NN P +GLGTW + PGEV +AV A++ GYR IDCA Y NEKE+GE I +K
Sbjct: 9 NNGKFMPAIGLGTWLAAPGEVGKAVTLALENGYRLIDCARFYKNEKEIGEMGIEPFLKNH 68
Query: 271 VVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTD 450
RE+LF+TSKLW + +R + E++ +L +YLDLYLIHWP A K D S P
Sbjct: 69 --PREELFVTSKLW--MDQVTRIRESCLESIQDLKCKYLDLYLIHWPIALKVDASNPPKP 124
Query: 451 QSGKIQFSDVDYVDTWKAMEPLVKEG 528
+ F D+D + W+ ME LV EG
Sbjct: 125 E----DFLDMDITEIWQEMERLVDEG 146
>UniRef50_Q6TY50 Cluster: Reductase 2; n=10; Magnoliophyta|Rep:
Reductase 2 - Hydrangea macrophylla (Bigleaf hydrangea)
Length = 321
Score = 119 bits (286), Expect = 5e-26
Identities = 62/145 (42%), Positives = 90/145 (62%), Gaps = 4/145 (2%)
Frame = +1
Query: 106 KCPILGLGTWKSKPGE---VTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVV 276
K P+LGLGT P + V +AV +A+ +GYRH D A +Y +E+ +G+AI + EG++
Sbjct: 16 KMPVLGLGTAADPPVDPETVRKAVTEALKLGYRHFDTAALYNSEQPLGDAIAEALGEGLI 75
Query: 277 -TREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQ 453
+R++LFITSKLW + + V ALQ+TL NL ++Y+D+YLIHWP + K +P
Sbjct: 76 KSRDELFITSKLWCSDAHRENVEPALQKTLKNLKLEYIDMYLIHWPVSSKPGNYEYPIK- 134
Query: 454 SGKIQFSDVDYVDTWKAMEPLVKEG 528
K F +DY W+AME K G
Sbjct: 135 --KEDFLQMDYKSVWEAMEECQKLG 157
>UniRef50_P23901 Cluster: Aldose reductase; n=9; Poaceae|Rep: Aldose
reductase - Hordeum vulgare (Barley)
Length = 320
Score = 118 bits (285), Expect = 7e-26
Identities = 62/140 (44%), Positives = 89/140 (63%), Gaps = 1/140 (0%)
Frame = +1
Query: 112 PILGLGTWKSKPGEVTQAVKDAI-DIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 288
P +GLGTW++ + +V+ AI + GYRH+D A YG EKEVG+ + + ++ G+ R+D
Sbjct: 25 PAVGLGTWRAG-SDTAHSVRTAITEAGYRHVDTAAEYGVEKEVGKGLKAAMEAGI-DRKD 82
Query: 289 LFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKIQ 468
LF+TSK+W T P+ VR AL+ TL +L + Y+DLY IHWP K DG+ P + ++
Sbjct: 83 LFVTSKIWCTNLAPERVRPALENTLKDLQLDYIDLYHIHWPFRLK-DGAHMPPEAGEVLE 141
Query: 469 FSDVDYVDTWKAMEPLVKEG 528
F D WK ME LVK+G
Sbjct: 142 F---DMEGVWKEMENLVKDG 158
>UniRef50_Q0CLQ2 Cluster: Putative uncharacterized protein; n=1;
Aspergillus terreus NIH2624|Rep: Putative
uncharacterized protein - Aspergillus terreus (strain
NIH 2624)
Length = 301
Score = 118 bits (283), Expect = 1e-25
Identities = 70/161 (43%), Positives = 90/161 (55%), Gaps = 22/161 (13%)
Frame = +1
Query: 112 PILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 291
P +GLGTW SKP EV AV+ A+ +GYRHID A Y NE EVG K+ V R+ +
Sbjct: 16 PAVGLGTWLSKPHEVENAVETALRLGYRHIDAAACYLNENEVGNG----WKKSGVPRDQI 71
Query: 292 FITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYL--------------------IHWP 411
FITSKLWNT H PD V A+ +TL +L YLDLYL IHWP
Sbjct: 72 FITSKLWNTHHHPDHVEEAVNKTLKDLQTDYLDLYLVFPSLLVLIHDLLSLLTNNKIHWP 131
Query: 412 QAYKE-DGSLFPTDQ-SGKIQFSDVDYVDTWKAMEPLVKEG 528
A++ + +L P D S + + +++ DTW A+E LV G
Sbjct: 132 VAFEHTNETLTPIDPVSKRFRLANIPIADTWAALEKLVDAG 172
>UniRef50_A6RKL9 Cluster: Putative uncharacterized protein; n=3;
Sclerotiniaceae|Rep: Putative uncharacterized protein -
Botryotinia fuckeliana B05.10
Length = 360
Score = 118 bits (283), Expect = 1e-25
Identities = 62/140 (44%), Positives = 84/140 (60%), Gaps = 3/140 (2%)
Frame = +1
Query: 112 PILGLGTWKSK--PGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRE 285
P++G GTW K P T+AV AI+IGYR IDCA VYGNE VG I +K + RE
Sbjct: 40 PLIGFGTWNLKVSPENTTEAVAYAIEIGYRQIDCAAVYGNEVAVGRGIEEGLKRAGLKRE 99
Query: 286 DLFITSKLWNTFHRP-DLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGK 462
D+++TSKLWN H + V L +TL +L ++YLDLYLIHWP + +G+
Sbjct: 100 DIWVTSKLWNDHHGSYENVEKGLNQTLQDLGLEYLDLYLIHWPIGFSSNGA--------- 150
Query: 463 IQFSDVDYVDTWKAMEPLVK 522
++D+V T+K+M L K
Sbjct: 151 ---KNLDHVQTYKSMISLPK 167
>UniRef50_Q6RZX1 Cluster: Gld1; n=22; Pezizomycotina|Rep: Gld1 -
Trichoderma atroviride (Hypocrea atroviridis)
Length = 327
Score = 117 bits (281), Expect = 2e-25
Identities = 64/161 (39%), Positives = 92/161 (57%), Gaps = 7/161 (4%)
Frame = +1
Query: 67 MSSVPFVEFNNELKCPILGLGTWKSK--PGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVG 240
+SS + N K P +G GT+ ++ GE AV A+D+GYRH+DCA+ Y NE EVG
Sbjct: 10 LSSTTYT-LNTGAKIPAVGFGTFANEGAKGETYAAVTKALDVGYRHLDCAWFYLNEDEVG 68
Query: 241 EAITSKI-KEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP-Q 414
+AI + + VTR+DLFI +K+WN H P+ V+ + + + +NL V Y+DL+L+HWP
Sbjct: 69 DAIRDFLARRPDVTRKDLFICTKVWNHLHEPEDVKWSAKNSCENLKVDYIDLFLVHWPIA 128
Query: 415 AYKEDGSLFPTDQSGKIQFSDV---DYVDTWKAMEPLVKEG 528
A K GK + + TW+AME LV G
Sbjct: 129 AEKNADRTVKIGPDGKYVINKALTENPEPTWRAMEELVDSG 169
>UniRef50_Q8WRT0 Cluster: 3-dehydrecdysone 3b-reductase; n=1;
Trichoplusia ni|Rep: 3-dehydrecdysone 3b-reductase -
Trichoplusia ni (Cabbage looper)
Length = 308
Score = 116 bits (280), Expect = 3e-25
Identities = 67/151 (44%), Positives = 89/151 (58%), Gaps = 1/151 (0%)
Frame = +1
Query: 79 PFVEFNNELKCPILGLGTWK-SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 255
P + N+ P L LGT+ +V QAV AI GYRHID A +YGNE+EVG+ I
Sbjct: 25 PLKQLNDGNAIPSLALGTFGFGDIPKVRQAVLWAIQAGYRHIDTAALYGNEEEVGKGIAD 84
Query: 256 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGS 435
I++G+V RE+LF+T+KLWN H V AL+E+L L + Y+DLYLIH P+A E+G
Sbjct: 85 AIQQGLVKREELFVTTKLWNDKHGRHQVVPALRESLTKLGLSYVDLYLIHSPEATNENGD 144
Query: 436 LFPTDQSGKIQFSDVDYVDTWKAMEPLVKEG 528
P D+D ++TW ME K G
Sbjct: 145 --PV---------DIDVLNTWNGMEEAKKLG 164
>UniRef50_A5E082 Cluster: GCY protein; n=4; Saccharomycetales|Rep:
GCY protein - Lodderomyces elongisporus (Yeast)
(Saccharomyces elongisporus)
Length = 295
Score = 116 bits (279), Expect = 3e-25
Identities = 60/146 (41%), Positives = 86/146 (58%), Gaps = 1/146 (0%)
Frame = +1
Query: 94 NNELKCPILGLGTWKSKPGEVT-QAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEG 270
NN LK P +GLGTW + + +A A+ GY+HID A YGNE +VG AI +
Sbjct: 15 NNGLKIPAIGLGTWLADEEDAAYKATLTALKNGYKHIDTAAAYGNEDQVGRAIA----DS 70
Query: 271 VVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTD 450
V+R+++F+T+KLWN H+ GAL E+L L ++Y+DLYLIHWP D
Sbjct: 71 GVSRDEIFVTTKLWNDQHKDP--EGALDESLKKLGLEYVDLYLIHWP---------LSVD 119
Query: 451 QSGKIQFSDVDYVDTWKAMEPLVKEG 528
+ + D D+VDTW+ ++ + KEG
Sbjct: 120 PKTEKPYDDYDFVDTWRNLQKIYKEG 145
>UniRef50_P28475 Cluster: NADP-dependent D-sorbitol-6-phosphate
dehydrogenase; n=71; Magnoliophyta|Rep: NADP-dependent
D-sorbitol-6-phosphate dehydrogenase - Malus domestica
(Apple) (Malus sylvestris)
Length = 310
Score = 116 bits (279), Expect = 3e-25
Identities = 58/152 (38%), Positives = 88/152 (57%), Gaps = 4/152 (2%)
Frame = +1
Query: 85 VEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 264
V ++ + P++GLG W+ + E+ + + +AI IGYRH DCA Y +E +VGEA+ K
Sbjct: 4 VTLSSGYEMPVIGLGLWRLEKDELKEVILNAIKIGYRHFDCAAHYKSEADVGEALAEAFK 63
Query: 265 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 444
G+V RE+LFIT+K+WN+ H V A + +L+ L + YLDLYL+H+P K +
Sbjct: 64 TGLVKREELFITTKIWNSDH--GHVVEACKNSLEKLQIDYLDLYLVHYPMPTKHNAIGKT 121
Query: 445 TDQSGKIQFSDVDYV----DTWKAMEPLVKEG 528
G+ + D+D TW+ ME V G
Sbjct: 122 ASLLGEDKVLDIDVTISLQQTWEGMEKTVSLG 153
>UniRef50_A1D4E3 Cluster: D-xylose reductase (Xyl1), putative; n=5;
Pezizomycotina|Rep: D-xylose reductase (Xyl1), putative
- Neosartorya fischeri (strain ATCC 1020 / DSM 3700 /
NRRL 181)(Aspergillus fischerianus (strain ATCC 1020 /
DSM 3700 / NRRL 181))
Length = 321
Score = 116 bits (278), Expect = 5e-25
Identities = 58/154 (37%), Positives = 85/154 (55%), Gaps = 5/154 (3%)
Frame = +1
Query: 73 SVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAIT 252
+ P + N+ P++G G WK + AI GYR D A YGNE E G+ +
Sbjct: 2 TTPSTKLNSGYDMPLVGFGLWKVNNETCADQIYHAIKAGYRLFDGACDYGNEVEAGKGVA 61
Query: 253 SKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA--YKE 426
I+EG+V REDLFI SKLWN+FH D V ++ L + + Y DL+++H+P A Y +
Sbjct: 62 RAIQEGIVKREDLFIVSKLWNSFHDGDRVEPICRKQLADWGLDYFDLFIVHFPIALKYVD 121
Query: 427 DGSLFP---TDQSGKIQFSDVDYVDTWKAMEPLV 519
+P ++ K++FS+ +TW AME LV
Sbjct: 122 PAVRYPPGWLSENNKLEFSNASIQETWTAMESLV 155
>UniRef50_Q6NII7 Cluster: Putative oxidoreductase; n=2;
Corynebacterium|Rep: Putative oxidoreductase -
Corynebacterium diphtheriae
Length = 290
Score = 115 bits (276), Expect = 8e-25
Identities = 48/116 (41%), Positives = 74/116 (63%)
Frame = +1
Query: 76 VPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 255
+P + N+ + P +G GT+K + + +AV+ AI++GYRHID A +Y NE+EVG A+
Sbjct: 11 IPTITLNDGTEMPAIGFGTYKLREQDAYRAVRSAIEVGYRHIDTASLYKNEEEVGRAVAD 70
Query: 256 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYK 423
I G V R++LFIT+K+WN H L + + QE+L L + Y+D ++HWP K
Sbjct: 71 AITAGEVARDELFITTKVWNDMHGDQLTQRSFQESLHRLGLDYIDCCMVHWPWPQK 126
>UniRef50_Q41399 Cluster: Chalcone reductase; n=4;
eudicotyledons|Rep: Chalcone reductase - Sesbania
rostrata
Length = 322
Score = 115 bits (276), Expect = 8e-25
Identities = 63/155 (40%), Positives = 91/155 (58%), Gaps = 4/155 (2%)
Frame = +1
Query: 76 VPFVEFNNELKCPILGLGTW-KSKPGE--VTQAVKDAIDIGYRHIDCAYVYGNEKEVGEA 246
+P V N+ K P++G+GT +S+P + DAI +GYRH D A VYG E+ +G A
Sbjct: 6 IPEVLLNSGHKMPVIGMGTSVESRPSNDVLASIFVDAIQVGYRHFDSASVYGTEEAIGMA 65
Query: 247 ITSKIKEGVV-TREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYK 423
++ I++G++ +R+++FITSK WNT DL+ AL+ TL L ++Y+DLYLIHWP +
Sbjct: 66 VSKAIEQGLIKSRDEVFITSKPWNTDAHHDLIVPALKTTLKKLGMEYVDLYLIHWPVRLR 125
Query: 424 EDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEG 528
D L K D TWKAME + G
Sbjct: 126 HD--LENPVIFSKEDLLPFDIEGTWKAMEECYRLG 158
>UniRef50_P14065 Cluster: Protein GCY; n=13; Saccharomycetales|Rep:
Protein GCY - Saccharomyces cerevisiae (Baker's yeast)
Length = 312
Score = 114 bits (275), Expect = 1e-24
Identities = 64/161 (39%), Positives = 95/161 (59%), Gaps = 9/161 (5%)
Frame = +1
Query: 73 SVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAIT 252
S + N + P +GLGTW+SK + +AV A+ GYRHID A +Y NE +VG+A
Sbjct: 8 STKILSLNTGAQIPQIGLGTWQSKENDAYKAVLTALKDGYRHIDTAAIYRNEDQVGQA-- 65
Query: 253 SKIKEGVVTREDLFITSKLWNT-FHRPDLVRGALQETLDNLNVQYLDLYLIHWP----QA 417
IK+ V RE++F+T+KLW T H P++ AL ++L L + Y+DLYL+HWP A
Sbjct: 66 --IKDSGVPREEIFVTTKLWCTQHHEPEV---ALDQSLKRLGLDYVDLYLMHWPARLDPA 120
Query: 418 Y--KEDGSLFPTDQSGK--IQFSDVDYVDTWKAMEPLVKEG 528
Y ED PT + G + ++ +++ TW+ M+ L K G
Sbjct: 121 YIKNEDILSVPTKKDGSRAVDITNWNFIKTWELMQELPKTG 161
>UniRef50_UPI00015B4B22 Cluster: PREDICTED: similar to GA15457-PA;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
GA15457-PA - Nasonia vitripennis
Length = 388
Score = 113 bits (272), Expect = 2e-24
Identities = 62/140 (44%), Positives = 84/140 (60%), Gaps = 1/140 (0%)
Frame = +1
Query: 112 PILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 291
P +GLGT K E+ A+ A++ GYRHID A+ Y NE +G+ + +G RED+
Sbjct: 35 PAVGLGTSTIKLDEMDNAISSALENGYRHIDTAFSYDNEAAIGKILKKWFDKGG-KREDI 93
Query: 292 FITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSL-FPTDQSGKIQ 468
FITSKL + +RP V L+ +L +L + Y+D+YLIH P A KE +L D+ G
Sbjct: 94 FITSKLPSQGNRPQSVETYLKRSLKDLGLDYVDMYLIHTPFAVKEGENLSSKQDKDGNDL 153
Query: 469 FSDVDYVDTWKAMEPLVKEG 528
F DVD+ WKAME VKEG
Sbjct: 154 FDDVDHKALWKAMERQVKEG 173
>UniRef50_Q03PG5 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=1; Lactobacillus brevis ATCC
367|Rep: Aldo/keto reductase of diketogulonate reductase
family - Lactobacillus brevis (strain ATCC 367 / JCM
1170)
Length = 268
Score = 113 bits (272), Expect = 2e-24
Identities = 53/108 (49%), Positives = 69/108 (63%)
Frame = +1
Query: 88 EFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKE 267
+ +N + P+LG GT+ +V A+K A+D GYRH+DCA++YGNE VGEA IK
Sbjct: 5 QLSNGVTIPMLGFGTYLIDSKDVPAAIKTALDAGYRHLDCAHIYGNEPAVGEA----IKA 60
Query: 268 GVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 411
+ R DLFITSK+WN D A +TL +L + YLDLYLIHWP
Sbjct: 61 SGIDRSDLFITSKVWNADQGYDKTLAAFDQTLSDLQLDYLDLYLIHWP 108
>UniRef50_P26690 Cluster: NAD(P)H-dependent 6'-deoxychalcone
synthase; n=3; Papilionoideae|Rep: NAD(P)H-dependent
6'-deoxychalcone synthase - Glycine max (Soybean)
Length = 315
Score = 113 bits (272), Expect = 2e-24
Identities = 57/158 (36%), Positives = 95/158 (60%), Gaps = 2/158 (1%)
Frame = +1
Query: 61 VKMSSVPFVEFNNELKCPILGLGTWK--SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKE 234
+++ ++ F + + + P++G+G+ + + +A+ +A+ GYRH D A YG+E+
Sbjct: 5 IEIPTIVFPNSSAQQRMPVVGMGSAPDFTCKKDTKEAIIEAVKQGYRHFDTAAAYGSEQA 64
Query: 235 VGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQ 414
+GEA+ I G+V+R+DLF+TSKLW T + P LV AL+++L L ++YLDLYLIHWP
Sbjct: 65 LGEALKEAIHLGLVSRQDLFVTSKLWVTENHPHLVLPALRKSLKTLQLEYLDLYLIHWPL 124
Query: 415 AYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEG 528
+ + FP + + F D W++ME K G
Sbjct: 125 SSQPGKFSFPIEVEDLLPF---DVKGVWESMEECQKLG 159
>UniRef50_Q8F1G4 Cluster: Aldehyde reductase; n=8; Bacteria|Rep:
Aldehyde reductase - Leptospira interrogans
Length = 278
Score = 113 bits (271), Expect = 3e-24
Identities = 54/114 (47%), Positives = 76/114 (66%), Gaps = 1/114 (0%)
Frame = +1
Query: 85 VEFNNELKCPILGLGTWKSKPG-EVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 261
+ NN + PILGLG WK+K G E +AV +A++ GYRHID A +Y NE +VG+AI
Sbjct: 12 IMLNNGISMPILGLGVWKTKSGKECKEAVLNALEAGYRHIDTARIYDNEVDVGQAI---- 67
Query: 262 KEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYK 423
+E + R+++FIT+KLWN D R AL+ +LD L + ++DLYLIH+P K
Sbjct: 68 RESGIPRKEIFITTKLWNADQGSDKTRKALENSLDRLGIDFVDLYLIHFPVTSK 121
>UniRef50_Q16K66 Cluster: Aldo-keto reductase; n=2; Aedes
aegypti|Rep: Aldo-keto reductase - Aedes aegypti
(Yellowfever mosquito)
Length = 303
Score = 113 bits (271), Expect = 3e-24
Identities = 59/147 (40%), Positives = 89/147 (60%), Gaps = 2/147 (1%)
Frame = +1
Query: 94 NNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 273
NN P +GLGT+K + A+K A++ GYR ID A+VY NE+ VG+A+ +G
Sbjct: 5 NNGHSIPPIGLGTYKITGSDGVAAIKSAVEFGYRLIDTAFVYNNEQVVGQALREIFSQGN 64
Query: 274 -VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTD 450
+ RED+FI SKL TFHRP+ V + +L+ L + Y+DLYL+H P A ++ G D
Sbjct: 65 DINREDVFIVSKLGPTFHRPEAVEKGCRLSLERLGLDYVDLYLMHTPVAARDSG-----D 119
Query: 451 QSGKIQFSD-VDYVDTWKAMEPLVKEG 528
+ + + D V ++TWKA+E ++G
Sbjct: 120 GNDRSEIDDEVTPLETWKALEECQRKG 146
>UniRef50_Q8J0K1 Cluster: 4-dihydromethyltrisporate dehydrogenase;
n=2; Parasitella parasitica|Rep:
4-dihydromethyltrisporate dehydrogenase - Parasitella
parasitica
Length = 321
Score = 113 bits (271), Expect = 3e-24
Identities = 61/147 (41%), Positives = 79/147 (53%), Gaps = 6/147 (4%)
Frame = +1
Query: 100 ELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVT 279
E K P+ G G WK + + + AI IGYR D A YGNE EVG I IKEG+V
Sbjct: 12 EDKMPLRGFGCWKIEKKDAENTIYQAIKIGYRLFDGACDYGNEVEVGRGINKAIKEGLVK 71
Query: 280 REDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHW--PQAYKEDGSLFPTD- 450
RE+LFI +KLWNTFH VR A L + ++Y DLYLIH+ P Y + +P +
Sbjct: 72 REELFIVTKLWNTFHSKQHVRTAFDRQLKDWGLEYFDLYLIHFPIPLQYVDPAVSYPPEW 131
Query: 451 ---QSGKIQFSDVDYVDTWKAMEPLVK 522
+ K+ F + W ME LV+
Sbjct: 132 YVPHADKLNFERSPIHECWAEMEKLVQ 158
>UniRef50_A6ESC0 Cluster: ARA1; n=1; unidentified eubacterium
SCB49|Rep: ARA1 - unidentified eubacterium SCB49
Length = 280
Score = 111 bits (268), Expect = 7e-24
Identities = 62/150 (41%), Positives = 87/150 (58%), Gaps = 1/150 (0%)
Frame = +1
Query: 82 FVEFNNELKCPILGLGTWKSKPGEVT-QAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSK 258
+ + NN + P +G GTW++ G+ A+K AID GY+HID A +Y NEK VG I
Sbjct: 4 YFKLNNNINIPAIGFGTWQTPDGQTAINAIKTAIDAGYKHIDAAAIYKNEKGVGLGI--- 60
Query: 259 IKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSL 438
KE + R+DLF+TSK+WN + A T+++L + YLDLYLIHWP A +
Sbjct: 61 -KEANIDRKDLFVTSKVWNEQRGYENTLKAFDNTINDLQLDYLDLYLIHWPAAAHQ---- 115
Query: 439 FPTDQSGKIQFSDVDYVDTWKAMEPLVKEG 528
++ K Q ++ DTW AME L K+G
Sbjct: 116 ---FENWK-QLNN----DTWSAMEKLYKDG 137
>UniRef50_Q6CFG7 Cluster: Yarrowia lipolytica chromosome B of strain
CLIB122 of Yarrowia lipolytica; n=9; Ascomycota|Rep:
Yarrowia lipolytica chromosome B of strain CLIB122 of
Yarrowia lipolytica - Yarrowia lipolytica (Candida
lipolytica)
Length = 337
Score = 111 bits (268), Expect = 7e-24
Identities = 64/158 (40%), Positives = 91/158 (57%), Gaps = 4/158 (2%)
Frame = +1
Query: 67 MSSVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAI-DIGYRHIDCAYVYGNEKEVGE 243
M+S+ F NN P +GLGTWKS EV AV+ A+ + GYRHID A+ Y NE VG
Sbjct: 29 MTSLDFT-LNNGKTIPAIGLGTWKSTTEEVAGAVECALTEGGYRHIDTAFNYRNEDAVGL 87
Query: 244 AITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYK 423
I +++G V RED+F+T+K+W T+H D V L +L+ L + Y+D+ LIHWP
Sbjct: 88 GIKRAMEKG-VKREDIFVTTKIWVTYH--DRVEENLDMSLERLGLDYVDMLLIHWPVPLN 144
Query: 424 EDGS--LFPTDQSGKIQFSDV-DYVDTWKAMEPLVKEG 528
+G+ ++P G + TWK ME ++K G
Sbjct: 145 PNGNDPVYPLRPDGSRDIDESGSQPKTWKQMEAVLKTG 182
>UniRef50_Q5FK98 Cluster: Oxidoreductase; n=8; Lactobacillales|Rep:
Oxidoreductase - Lactobacillus acidophilus
Length = 285
Score = 111 bits (267), Expect = 1e-23
Identities = 60/146 (41%), Positives = 90/146 (61%), Gaps = 1/146 (0%)
Frame = +1
Query: 94 NNELKCPILGLGTWKSKPGEVTQ-AVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEG 270
NN +K PI+G GTW++ GEV + +V A++ GYRHID A YGNE VG AI K G
Sbjct: 13 NNGVKIPIIGFGTWQTPDGEVAEESVLAALNCGYRHIDTASAYGNEDSVGRAIQ---KSG 69
Query: 271 VVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTD 450
+ R +LFIT+KLWN+ H + + A+ ++L +L + YLD+YLIHW P
Sbjct: 70 I-NRHELFITTKLWNSDHGYEKTKKAIDQSLLDLKLDYLDMYLIHW-----------PNP 117
Query: 451 QSGKIQFSDVDYVDTWKAMEPLVKEG 528
S + +++++ ++W+AME V+ G
Sbjct: 118 SSMRDHWAEIN-AESWRAMEEAVRAG 142
>UniRef50_P38115 Cluster: D-arabinose dehydrogenase [NAD(P)+] heavy
chain; n=3; Saccharomycetaceae|Rep: D-arabinose
dehydrogenase [NAD(P)+] heavy chain - Saccharomyces
cerevisiae (Baker's yeast)
Length = 344
Score = 111 bits (267), Expect = 1e-23
Identities = 65/156 (41%), Positives = 91/156 (58%), Gaps = 11/156 (7%)
Frame = +1
Query: 82 FVEFNNELKCPILGLGTWK--SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 255
+ NN ++ P LGLGT K E QAVK AI GYRHID A+ Y E VGEAI
Sbjct: 24 YFSLNNGVRIPALGLGTANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKE 83
Query: 256 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKE--- 426
+++G + REDLFIT+K+W D V +L E+L L ++Y+DL L HWP +++
Sbjct: 84 LLEDGSIKREDLFITTKVWPVLW--DEVDRSLNESLKALGLEYVDLLLQHWPLCFEKIKD 141
Query: 427 ----DGSL-FPTDQSGKIQF-SDVDYVDTWKAMEPL 516
G + P D SGK + +D DY++T+K +E +
Sbjct: 142 PKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKI 177
>UniRef50_Q88SL1 Cluster: Oxidoreductase; n=51; Lactobacillales|Rep:
Oxidoreductase - Lactobacillus plantarum
Length = 286
Score = 111 bits (266), Expect = 1e-23
Identities = 54/107 (50%), Positives = 69/107 (64%), Gaps = 1/107 (0%)
Frame = +1
Query: 94 NNELKCPILGLGTWKSKPGEVT-QAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEG 270
NN K PI+G GTW++ G+V +V A+ GYRHID A YGNE+ VG+AI +
Sbjct: 14 NNGTKIPIVGFGTWQTPDGQVAYDSVLAALKAGYRHIDTAAAYGNEESVGKAIA----DS 69
Query: 271 VVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 411
V REDLF+T+KLWN H D + AL +L L + Y+DLYLIHWP
Sbjct: 70 GVAREDLFVTTKLWNADHGYDAAKKALDTSLAKLGLDYVDLYLIHWP 116
>UniRef50_Q7XY49 Cluster: Mannose 6-phosphate reductase; n=1;
Griffithsia japonica|Rep: Mannose 6-phosphate reductase
- Griffithsia japonica (Red alga)
Length = 174
Score = 110 bits (265), Expect = 2e-23
Identities = 53/99 (53%), Positives = 65/99 (65%)
Frame = +1
Query: 106 KCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRE 285
K P+ G GTWK+ E QAV A+ GYRHIDCA VY NE VG AI+ I GVV RE
Sbjct: 13 KMPLNGFGTWKASVEETEQAVTAALRAGYRHIDCAAVYWNEAAVGTAISKAISGGVVKRE 72
Query: 286 DLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLI 402
DLFITSK+WNT H D V + +++L + V Y DL+L+
Sbjct: 73 DLFITSKVWNTCHATDKVVDSCRQSLKDHQVDYFDLFLV 111
>UniRef50_Q7R2T6 Cluster: GLP_291_56367_57278; n=1; Giardia lamblia
ATCC 50803|Rep: GLP_291_56367_57278 - Giardia lamblia
ATCC 50803
Length = 303
Score = 110 bits (265), Expect = 2e-23
Identities = 57/140 (40%), Positives = 78/140 (55%), Gaps = 4/140 (2%)
Frame = +1
Query: 112 PILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV--VTRE 285
P +G GT+ + E A++ A+ +GYRH DCAY YGNE+ +GE + V RE
Sbjct: 6 PCVGFGTYLVEDPE---AIRSAVKLGYRHFDCAYRYGNERMIGEVFKEIFNDDSYGVKRE 62
Query: 286 DLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKE--DGSLFPTDQSG 459
DL+I SKLW FH P+ V + ETL +L ++YLD++L+HWP A K D +D G
Sbjct: 63 DLWIVSKLWPNFHEPEKVAYQISETLRDLQLEYLDVFLMHWPLAIKHLADRDYASSDGKG 122
Query: 460 KIQFSDVDYVDTWKAMEPLV 519
TW+AME V
Sbjct: 123 GTLLGTTPIRKTWEAMEACV 142
>UniRef50_Q17G72 Cluster: Aldo-keto reductase; n=9;
Endopterygota|Rep: Aldo-keto reductase - Aedes aegypti
(Yellowfever mosquito)
Length = 316
Score = 110 bits (265), Expect = 2e-23
Identities = 56/148 (37%), Positives = 84/148 (56%)
Frame = +1
Query: 85 VEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 264
+ F N P LG GTW++ EV +A+ +A++ GYRHID A VY NEK +G+ + +
Sbjct: 7 ITFENGTTMPALGFGTWRASDEEVEKALNEALEAGYRHIDTAPVYLNEKTIGKVLKEWMD 66
Query: 265 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 444
G VTR++LFI +KL R V L+ +LD+L ++Y+DLY +H P E F
Sbjct: 67 AGKVTRDELFIVTKLPPHGTRASTVEKFLKNSLDDLQLEYVDLYHVHVPFTVPEVDGPFL 126
Query: 445 TDQSGKIQFSDVDYVDTWKAMEPLVKEG 528
+ + + D+V WKAME + + G
Sbjct: 127 VEDGLIVLETTTDHVALWKAMEEVYEAG 154
>UniRef50_Q4JX70 Cluster: Putative oxidoreductase; n=1;
Corynebacterium jeikeium K411|Rep: Putative
oxidoreductase - Corynebacterium jeikeium (strain K411)
Length = 285
Score = 110 bits (264), Expect = 2e-23
Identities = 57/137 (41%), Positives = 80/137 (58%)
Frame = +1
Query: 64 KMSSVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGE 243
K ++VP +E N+ P LGLG W+ + +V+ AI+ GYRHID A +YGNE+ VG
Sbjct: 4 KNNAVPTLEMNDGKTTPQLGLGVWQLSDEDTYTSVRAAIETGYRHIDTAAIYGNEEAVGR 63
Query: 244 AITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYK 423
A+ +K G V RE+LFIT+KLWN + A E+ L + Y+DLYL+HWP +
Sbjct: 64 AVADAVKAGDVQREELFITTKLWNADQA--CGKEAFAESQKKLGMDYVDLYLLHWP-CPQ 120
Query: 424 EDGSLFPTDQSGKIQFS 474
D + D +IQ S
Sbjct: 121 ADSFVQAYDSMAEIQQS 137
>UniRef50_A6W8E7 Cluster: 2,5-didehydrogluconate reductase; n=3;
Actinomycetales|Rep: 2,5-didehydrogluconate reductase -
Kineococcus radiotolerans SRS30216
Length = 289
Score = 110 bits (264), Expect = 2e-23
Identities = 61/151 (40%), Positives = 88/151 (58%)
Frame = +1
Query: 58 TVKMSSVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEV 237
+V +VP + N+ + P LG G ++ +PG+ QAVK A+D+GYRHID A +YGNE EV
Sbjct: 6 SVSAMTVPTILLNDGREIPQLGFGVFQIEPGDTAQAVKTALDLGYRHIDTAQMYGNEAEV 65
Query: 238 GEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA 417
+ I + V R+++++TSKL N FH PD R A+ ++++ L +DLYLIHWP
Sbjct: 66 AQGIA----DSGVPRDEIWVTSKLNNGFHEPDAARKAVDDSVEKLRGP-IDLYLIHWP-- 118
Query: 418 YKEDGSLFPTDQSGKIQFSDVDYVDTWKAME 510
PT G D+V TWK +E
Sbjct: 119 -------LPTLYGG-------DFVSTWKVLE 135
>UniRef50_Q23320 Cluster: Putative uncharacterized protein; n=4;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 320
Score = 110 bits (264), Expect = 2e-23
Identities = 57/147 (38%), Positives = 83/147 (56%)
Frame = +1
Query: 70 SSVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAI 249
S VP +N + P +GLGTW+ E +++A+ GYRHID A +Y NE ++G+A+
Sbjct: 3 SKVPIFTLSNGVLMPSIGLGTWQMTGEEGKTVIRNAVLAGYRHIDTATLYQNEHQIGDAL 62
Query: 250 TSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKED 429
EG++ RED+FIT+K + PD+V AL+ +L L + Y+DLYL H P + K+D
Sbjct: 63 AELFAEGILKREDIFITTKAFCHEVAPDVVEEALRNSLKRLRLDYVDLYLAHIPASTKDD 122
Query: 430 GSLFPTDQSGKIQFSDVDYVDTWKAME 510
GS SDV D W+ E
Sbjct: 123 GSF----------RSDVKVEDIWRGFE 139
>UniRef50_Q03TW0 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=1; Lactobacillus brevis ATCC
367|Rep: Aldo/keto reductase of diketogulonate reductase
family - Lactobacillus brevis (strain ATCC 367 / JCM
1170)
Length = 293
Score = 109 bits (263), Expect = 3e-23
Identities = 66/154 (42%), Positives = 86/154 (55%), Gaps = 1/154 (0%)
Frame = +1
Query: 70 SSVPFVEFNNELKCPILGLGTWKSKPGEVTQ-AVKDAIDIGYRHIDCAYVYGNEKEVGEA 246
+ +P + NN + P LGLG ++ E T+ A+K A+ GYRHID A YGNE+ VGEA
Sbjct: 9 NDIPDLPMNNGHQIPQLGLGVFQVDNAEDTKNAIKWALAAGYRHIDTAAYYGNEQWVGEA 68
Query: 247 ITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKE 426
I +E V R+ +F+TSKLWN+ D + A QETLD L + YLDLYLIHWP
Sbjct: 69 I----RESDVPRDQIFVTSKLWNSVRGYDETQAAFQETLDKLGLDYLDLYLIHWPAP--- 121
Query: 427 DGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEG 528
Y+D+W+AME L K G
Sbjct: 122 ------------------GYLDSWRAMEDLYKAG 137
>UniRef50_P22045 Cluster: Probable reductase; n=101; cellular
organisms|Rep: Probable reductase - Leishmania major
Length = 284
Score = 109 bits (262), Expect = 4e-23
Identities = 65/148 (43%), Positives = 86/148 (58%), Gaps = 1/148 (0%)
Frame = +1
Query: 85 VEFNNELKCPILGLGTWKSKPGEVTQ-AVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 261
V +N +K P GLG W+S GEVT+ AV A+ GYRHID A +Y NE+ VG +
Sbjct: 9 VTLSNGVKMPQFGLGVWQSPAGEVTENAVNWALCAGYRHIDTAAIYKNEESVGAGL---- 64
Query: 262 KEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLF 441
+ V RED+FIT+KLWNT + A +E+ L V Y+DLYLIHWP+ K+ S
Sbjct: 65 RASGVPREDVFITTKLWNTEQGYESTLAAFEESRQKLGVDYIDLYLIHWPRG-KDILS-- 121
Query: 442 PTDQSGKIQFSDVDYVDTWKAMEPLVKE 525
+ GK Y+D+W+A E L KE
Sbjct: 122 ---KEGK------KYLDSWRAFEQLYKE 140
>UniRef50_Q9HGY0 Cluster: Glycerol dehydrogenase; n=8;
Saccharomycetaceae|Rep: Glycerol dehydrogenase -
Zygosaccharomyces rouxii (Candida mogii)
Length = 310
Score = 108 bits (259), Expect = 9e-23
Identities = 62/161 (38%), Positives = 95/161 (59%), Gaps = 8/161 (4%)
Frame = +1
Query: 70 SSVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAI 249
+S ++ N P +GLGTW+SK E +AV +A+ GYRHID A VYGNE EVG+A
Sbjct: 6 NSTSTLKLNTGQTIPQVGLGTWRSKENEGYKAVIEALKAGYRHIDGAAVYGNEGEVGKA- 64
Query: 250 TSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYK-- 423
I++ V R ++F+T+KLW T R + AL ++L L + Y+ LYL+HWP +
Sbjct: 65 ---IQDSGVPRNEIFLTTKLWCTHQRNP--QEALDQSLQRLGLDYVGLYLVHWPVPLRTE 119
Query: 424 --EDGSLF----PTDQSGKIQFSDVDYVDTWKAMEPLVKEG 528
+DG+LF D S + + +++ TW+ M+ L++ G
Sbjct: 120 NIKDGNLFQFAEKPDGSKDVDL-EWNFIKTWELMQKLLESG 159
>UniRef50_UPI0000519CC2 Cluster: PREDICTED: similar to CG2767-PA;
n=1; Apis mellifera|Rep: PREDICTED: similar to CG2767-PA
- Apis mellifera
Length = 321
Score = 107 bits (257), Expect = 2e-22
Identities = 57/147 (38%), Positives = 89/147 (60%), Gaps = 2/147 (1%)
Frame = +1
Query: 94 NNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 273
N EL PI+G GTW+++ E+ A+ A++ GYRHID A Y NEK +G+ + +
Sbjct: 10 NGELM-PIIGFGTWQAQEKELEDALNIALEAGYRHIDTATSYENEKVIGDVLKNWFDSKK 68
Query: 274 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGS-LFPTD 450
+ R D+FI +KL +R + V ++ +L NL ++YLDLYLIH P +++ G L P D
Sbjct: 69 LKRSDIFIVTKLPAVGNRAEDVEKWIKTSLQNLRLEYLDLYLIHVPIGFEKVGDILHPFD 128
Query: 451 QSGKIQF-SDVDYVDTWKAMEPLVKEG 528
++G I+ + ++V+ W ME VK G
Sbjct: 129 ENGHIRLDNSTNHVEIWAEMEKQVKCG 155
>UniRef50_Q01J82 Cluster: OSIGBa0152K17.5 protein; n=28;
Magnoliophyta|Rep: OSIGBa0152K17.5 protein - Oryza
sativa (Rice)
Length = 323
Score = 107 bits (257), Expect = 2e-22
Identities = 58/154 (37%), Positives = 89/154 (57%), Gaps = 6/154 (3%)
Frame = +1
Query: 67 MSSVPFVEFNNEL--KCPILGLGTWKS---KPGEVTQAVKDAIDIGYRHIDCAYVYGNEK 231
M++VP V + P +G+GT S P A A+++G+RH D A +YG E
Sbjct: 1 MAAVPEVALRHGAGRPMPAVGVGTADSAATSPETKRGAALAALEVGFRHFDTAALYGTEA 60
Query: 232 EVGEAITSKIKEGVV-TREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHW 408
+GEAI + G+V +RE++F+T+KLW T P LV +L+E+L NL ++Y+DLYL+HW
Sbjct: 61 PLGEAIAEATRRGLVASREEVFVTTKLWCTQCHPGLVLPSLRESLRNLQMEYVDLYLVHW 120
Query: 409 PQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAME 510
P + K + P + + F D+ W+AME
Sbjct: 121 PISVKPGPPMLPVKREDAVPF---DFEGVWRAME 151
>UniRef50_UPI00015B40FA Cluster: PREDICTED: similar to CG2767-PA;
n=2; Nasonia vitripennis|Rep: PREDICTED: similar to
CG2767-PA - Nasonia vitripennis
Length = 356
Score = 107 bits (256), Expect = 2e-22
Identities = 56/142 (39%), Positives = 86/142 (60%), Gaps = 3/142 (2%)
Frame = +1
Query: 112 PILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 291
P++GLGTW+ P + AV A++ GYRHID A+ YGNE+ +G+ + +G REDL
Sbjct: 37 PMIGLGTWQMPPEAIEVAVTAALESGYRHIDTAFTYGNEEAIGKTLKKWFDKG-GKREDL 95
Query: 292 FITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLF--PTDQSGKI 465
FIT+KL R + V L+ +L+ L ++Y+++YLIH P A+ +D + + G +
Sbjct: 96 FITTKLPPIGMRAEYVESYLKLSLEKLGLEYVNMYLIHKPFAFVKDKYKYEPALNPDGSV 155
Query: 466 QF-SDVDYVDTWKAMEPLVKEG 528
+D D+V W+AME VK G
Sbjct: 156 VLDTDTDHVAIWRAMEKQVKAG 177
>UniRef50_A7CWF9 Cluster: Aldehyde reductase; n=2; Bacteria|Rep:
Aldehyde reductase - Opitutaceae bacterium TAV2
Length = 347
Score = 106 bits (255), Expect = 3e-22
Identities = 56/146 (38%), Positives = 81/146 (55%), Gaps = 5/146 (3%)
Frame = +1
Query: 106 KCPILGLGTWKSK---PGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV- 273
+ P +G+GT+ S PGEV +V A ++GYRH DCA VY NE+E+G +
Sbjct: 26 RMPAIGMGTFGSDHAAPGEVAASVYAAAELGYRHFDCAAVYSNEREIGATFRRILTSNTG 85
Query: 274 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP-QAYKEDGSLFPTD 450
+ REDL+ITSKLWN H V A +++L +L + YLDLYLIHWP + G +
Sbjct: 86 IRREDLWITSKLWNDKHAEADVIPAFEKSLRDLGLDYLDLYLIHWPFPNFHPPGCDVSSR 145
Query: 451 QSGKIQFSDVDYVDTWKAMEPLVKEG 528
+ +++ TW+ +E L G
Sbjct: 146 SPDARPYIHAEFMKTWRQLETLHDRG 171
>UniRef50_P82125 Cluster: 1,5-anhydro-D-fructose reductase; n=1; Sus
scrofa|Rep: 1,5-anhydro-D-fructose reductase - Sus
scrofa (Pig)
Length = 206
Score = 106 bits (255), Expect = 3e-22
Identities = 63/128 (49%), Positives = 73/128 (57%), Gaps = 1/128 (0%)
Frame = +1
Query: 106 KCPILGLGTWKSKPG-EVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTR 282
K P+LGLGTW++ PG EVT+AVK AID GYRH D AY+Y NE EVG I +KI EGVV R
Sbjct: 1 KIPVLGLGTWQAAPGGEVTEAVKVAIDTGYRHPDSAYLYHNEDEVGVGIQAKIDEGVVRR 60
Query: 283 EDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGK 462
EDLFI SK YLDL IHWP +K P D+SG
Sbjct: 61 EDLFIVSK----------------------KXXYLDLXNIHWPMQFKPGEVDLPVDRSGM 98
Query: 463 IQFSDVDY 486
I S+ D+
Sbjct: 99 IVASNTDF 106
>UniRef50_Q9FJK0 Cluster: Aldose reductase-like protein; n=3; core
eudicotyledons|Rep: Aldose reductase-like protein -
Arabidopsis thaliana (Mouse-ear cress)
Length = 316
Score = 106 bits (254), Expect = 4e-22
Identities = 58/141 (41%), Positives = 83/141 (58%), Gaps = 2/141 (1%)
Frame = +1
Query: 112 PILGLGTW-KSKPGEVT-QAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRE 285
P+LG+GT+ K E T AV AI IGYRH D A +YG+E+ +G A+ I G V R+
Sbjct: 15 PLLGMGTYCPQKDRESTISAVHQAIKIGYRHFDTAKIYGSEEALGTALGQAISYGTVQRD 74
Query: 286 DLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSGKI 465
DLF+TSKLW++ H + AL +TL + + YLD YL+HWP K G P + +
Sbjct: 75 DLFVTSKLWSSDHHDPI--SALIQTLKTMGLDYLDNYLVHWPIKLK-PGVSEPIPKEDEF 131
Query: 466 QFSDVDYVDTWKAMEPLVKEG 528
+ D+ +TW+ ME ++ G
Sbjct: 132 E-KDLGIEETWQGMERCLEMG 151
>UniRef50_Q7PM68 Cluster: ENSANGP00000014386; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000014386 - Anopheles gambiae
str. PEST
Length = 310
Score = 106 bits (254), Expect = 4e-22
Identities = 55/145 (37%), Positives = 79/145 (54%), Gaps = 1/145 (0%)
Frame = +1
Query: 97 NELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKE-GV 273
+ + P +GLGT+ + +A++ AID+GYR D A YGNE VGEAI KI+E
Sbjct: 13 HSIALPTIGLGTYSILGADGKEAIRTAIDVGYRMFDTAVAYGNEAIVGEAIREKIRECNN 72
Query: 274 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQ 453
+TR+D FI SKL ++HR DLV + TLD L + Y+DLYL+H P A + +
Sbjct: 73 LTRDDFFIISKLSGSYHRQDLVEKCCRMTLDRLGMDYVDLYLMHTPVALQSEKKCARNGT 132
Query: 454 SGKIQFSDVDYVDTWKAMEPLVKEG 528
+ + W +E +EG
Sbjct: 133 KLNAIDDSIAPTEAWIGLEQCYQEG 157
>UniRef50_Q6C2L0 Cluster: Yarrowia lipolytica chromosome F of strain
CLIB122 of Yarrowia lipolytica; n=3; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome F of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 324
Score = 106 bits (254), Expect = 4e-22
Identities = 58/154 (37%), Positives = 93/154 (60%), Gaps = 6/154 (3%)
Frame = +1
Query: 67 MSSVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEA 246
MS + N+ P LGLGT + G V + V AI GYRHID A++YG+E +VG+
Sbjct: 1 MSITDSFKLNDGHSIPALGLGT--ASDGNVEEVVYAAIKNGYRHIDTAFIYGSEVDVGKG 58
Query: 247 ITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKE 426
I I E +V RE+LF+T+K+W TF+ + V +L +L +L++ Y+DL L+HWP +
Sbjct: 59 IKRAIDEELVKRENLFVTTKVWPTFY--NRVSESLDISLKDLSLDYVDLLLVHWPVSLLA 116
Query: 427 DG----SLFPTDQSGKIQFSDV--DYVDTWKAME 510
D +++ + G +++SD D++ T+K +E
Sbjct: 117 DSDDPRAIYLVNTDGSVRYSDSLDDWITTYKQIE 150
>UniRef50_A3LTU8 Cluster: D-arabinose dehydrogenase; n=5;
Saccharomycetales|Rep: D-arabinose dehydrogenase -
Pichia stipitis (Yeast)
Length = 326
Score = 106 bits (254), Expect = 4e-22
Identities = 60/163 (36%), Positives = 94/163 (57%), Gaps = 9/163 (5%)
Frame = +1
Query: 70 SSVPFVEFNNELKCPILGLGTWKSK-PGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEA 246
+ V FV +N P LGLGT + P E+ + V A+ GYRHID A+ YG E+ +G+A
Sbjct: 6 TDVDFV-LSNGKTIPALGLGTVPPEDPHELKEQVITAVKAGYRHIDTAWYYGTEEYIGQA 64
Query: 247 ITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKE 426
+ +EG+V REDLFIT+K+W +F R +L ++L +L + Y+DL+L HWP
Sbjct: 65 LKQLFEEGIVKREDLFITTKVWPSFWRNP--EKSLDKSLADLGLDYVDLFLQHWPVVLHG 122
Query: 427 DGSLF---PTDQSGKIQFSD-----VDYVDTWKAMEPLVKEGS 531
D + P D+ GK+ + D + Y+D + ++E ++ S
Sbjct: 123 DENGLPPQPRDKDGKLIYDDDPVSGIKYIDAYHSLEDIMDNTS 165
>UniRef50_P06632 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=8; Actinomycetales|Rep: 2,5-diketo-D-gluconic acid
reductase A - Corynebacterium sp. (strain ATCC 31090)
Length = 278
Score = 106 bits (254), Expect = 4e-22
Identities = 50/113 (44%), Positives = 72/113 (63%)
Frame = +1
Query: 73 SVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAIT 252
+VP + N+ P LG G +K P + +AV++A+++GYRHID A +YGNE+ VG AI
Sbjct: 2 TVPSIVLNDGNSIPQLGYGVFKVPPADTQRAVEEALEVGYRHIDTAAIYGNEEGVGAAIA 61
Query: 253 SKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 411
+ + R+DLFIT+KLWN H D A+ E+L L + +DLYL+HWP
Sbjct: 62 A----SGIARDDLFITTKLWNDRHDGDEPAAAIAESLAKLALDQVDLYLVHWP 110
>UniRef50_A2QL02 Cluster: Putative frameshift; n=1; Aspergillus
niger|Rep: Putative frameshift - Aspergillus niger
Length = 357
Score = 105 bits (253), Expect = 5e-22
Identities = 58/146 (39%), Positives = 85/146 (58%), Gaps = 1/146 (0%)
Frame = +1
Query: 94 NNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 273
N K P LG+GT++ P + V + G R ID A VYG E++VG I K+
Sbjct: 41 NTGAKIPALGVGTFQD-PDSQEETVCQVLQRGMRLIDTARVYGVEQQVGRGI----KKSG 95
Query: 274 VTREDLFITSKLW-NTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTD 450
V RE++F+ +KLW N FH PD V A+ ++L +L Y+DL L+H+P +K FP D
Sbjct: 96 VPREEIFLGTKLWCNDFH-PDDVERAVDDSLRDLYTPYVDLLLMHYPCTFKRGEDRFPRD 154
Query: 451 QSGKIQFSDVDYVDTWKAMEPLVKEG 528
G++ + +VDTW+A+E +VK G
Sbjct: 155 AEGRMIHGETTFVDTWRALEKVVKTG 180
>UniRef50_Q7N0E4 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=2; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase
A - Photorhabdus luminescens subsp. laumondii
Length = 292
Score = 105 bits (252), Expect = 7e-22
Identities = 51/115 (44%), Positives = 71/115 (61%)
Frame = +1
Query: 67 MSSVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEA 246
M + P + + P LGLG+W S ++ + + A+DIGYR ID A +Y NEK VG A
Sbjct: 1 MDNQPIIRLADGNHMPQLGLGSWASDDQQIAETIHAALDIGYRAIDTAAIYNNEKGVGNA 60
Query: 247 ITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 411
++E + RED+F+T+KLWN H R AL E+L+ L + Y+DLYLIHWP
Sbjct: 61 ----LQETDIPREDIFVTTKLWNDRHLD--ARAALTESLEKLQLDYVDLYLIHWP 109
>UniRef50_Q03XK0 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=3; Lactobacillales|Rep: Aldo/keto
reductase of diketogulonate reductase family -
Leuconostoc mesenteroides subsp. mesenteroides (strain
ATCC 8293 /NCDO 523)
Length = 292
Score = 105 bits (252), Expect = 7e-22
Identities = 52/104 (50%), Positives = 67/104 (64%), Gaps = 1/104 (0%)
Frame = +1
Query: 103 LKCPILGLGTWK-SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVT 279
++ P+LG G ++ + G QAV DAI GYR ID A YGNE+EVGEAI I +G+V
Sbjct: 10 IEMPLLGFGVFQVQEKGAAKQAVLDAIKTGYRLIDTAASYGNEREVGEAILEAINQGIVK 69
Query: 280 REDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 411
RE+LF+TSK+W A+Q +L LN+ YLDLYLIH P
Sbjct: 70 REELFVTSKMWVQDVSAQQATAAIQSSLQRLNLDYLDLYLIHQP 113
>UniRef50_Q83N50 Cluster: 2,5-diketo-D-gluconic acid reductase; n=2;
Tropheryma whipplei|Rep: 2,5-diketo-D-gluconic acid
reductase - Tropheryma whipplei (strain Twist)
(Whipple's bacillus)
Length = 283
Score = 104 bits (250), Expect = 1e-21
Identities = 52/115 (45%), Positives = 75/115 (65%)
Frame = +1
Query: 67 MSSVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEA 246
++ VP V + + P GLGT++ P E + V+ AI++GYRHID A +Y NE+EVG A
Sbjct: 6 LTYVPSVLLGDGVSIPQFGLGTYELPPNEASSVVQSAIELGYRHIDTASLYANEREVGRA 65
Query: 247 ITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 411
I S + RE+ F+T+KLWN+ +P R A + +LD L++ Y+DLYLIHWP
Sbjct: 66 IAS----SGIKREEFFVTTKLWNS-DQPK-PREAFERSLDLLSLDYVDLYLIHWP 114
>UniRef50_P70883 Cluster: AkrI; n=1; Butyrivibrio fibrisolvens|Rep:
AkrI - Butyrivibrio fibrisolvens
Length = 172
Score = 103 bits (248), Expect = 2e-21
Identities = 57/149 (38%), Positives = 79/149 (53%), Gaps = 1/149 (0%)
Frame = +1
Query: 85 VEFNNELKCPILGLGTWKSKP-GEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 261
++ NN P+ G GT+K K E +V+ A+ GYRHID A Y NEK V AI +
Sbjct: 8 IKLNNGTAIPMFGYGTYKIKDQNEAYNSVRLALKNGYRHIDTAAFYENEKFVANAIKDFM 67
Query: 262 KEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLF 441
+E RED+F+TSK W T D A ++T++ + + YLDLYL+HWP +Y D
Sbjct: 68 EESQTKREDIFVTSKAWKTELGYDKTLAAFEKTMNEMQMDYLDLYLVHWPASYAFDDDWE 127
Query: 442 PTDQSGKIQFSDVDYVDTWKAMEPLVKEG 528
T++ TWKAM + K G
Sbjct: 128 NTNR------------QTWKAMTEIYKSG 144
>UniRef50_A7BA05 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 292
Score = 103 bits (248), Expect = 2e-21
Identities = 46/100 (46%), Positives = 67/100 (67%)
Frame = +1
Query: 112 PILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 291
P+LG GT+K P + AV A+++GYRHID A +YGNE EVG A ++ + REDL
Sbjct: 28 PVLGFGTYKVAPEDTYDAVSRALEVGYRHIDTAQMYGNEAEVGAA----LEASGIAREDL 83
Query: 292 FITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 411
FIT+K+ N+ H PD +++ +L++L Y+DL L+HWP
Sbjct: 84 FITTKVDNSNHEPDRAAASIRRSLEDLRTDYVDLLLVHWP 123
>UniRef50_A6LZ55 Cluster: 2,5-didehydrogluconate reductase; n=1;
Clostridium beijerinckii NCIMB 8052|Rep:
2,5-didehydrogluconate reductase - Clostridium
beijerinckii NCIMB 8052
Length = 289
Score = 103 bits (248), Expect = 2e-21
Identities = 51/109 (46%), Positives = 72/109 (66%), Gaps = 1/109 (0%)
Frame = +1
Query: 97 NELKCPILGLGTWKSKPGEVTQ-AVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 273
N +K P +G G +K GE + AV +AI IGYRH D A +YGNEK++G AI ++
Sbjct: 12 NGIKIPQVGFGVYKLNKGEDFETAVGEAIKIGYRHFDTAKIYGNEKDLGLAI----EKSQ 67
Query: 274 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAY 420
+ RE+ FITSK+WNT H + + A ++T LNV+YLD+YLIH+ +Y
Sbjct: 68 IPREEFFITSKVWNTDHGYEATKKAFEQTCKKLNVEYLDMYLIHFASSY 116
>UniRef50_Q4Q5N9 Cluster: Prostaglandin f synthase, putative; n=7;
cellular organisms|Rep: Prostaglandin f synthase,
putative - Leishmania major
Length = 279
Score = 103 bits (248), Expect = 2e-21
Identities = 48/109 (44%), Positives = 70/109 (64%)
Frame = +1
Query: 85 VEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 264
V +N ++ P LG+GTW++K G +K A++ GYRH+D A+ Y NEK VG+ I+
Sbjct: 8 VTLSNGVQVPQLGIGTWEAKDGNEVVNIKWAVNAGYRHVDTAHYYKNEKGVGQGIS---- 63
Query: 265 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 411
E V R D+F+T+KLWN H + A +++ L V+Y+DLYLIHWP
Sbjct: 64 ECGVPRSDIFVTTKLWNYDHGYESALAAFEQSRQALGVEYVDLYLIHWP 112
>UniRef50_Q41E86 Cluster: 2,5-didehydrogluconate reductase; n=2;
Bacteria|Rep: 2,5-didehydrogluconate reductase -
Exiguobacterium sibiricum 255-15
Length = 274
Score = 103 bits (247), Expect = 3e-21
Identities = 59/152 (38%), Positives = 83/152 (54%)
Frame = +1
Query: 82 FVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 261
FV NN L P LG G +K EV +AV++A+ +GYR ID A +Y NE VG A+
Sbjct: 3 FVTLNNGLVMPQLGYGVFKVPEQEVYEAVREALRVGYRSIDTAMIYENEAGVGRAL---- 58
Query: 262 KEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLF 441
K+ + RED+F+T+K+WN + A + +L L V Y+DLYLIHWP D L
Sbjct: 59 KDSGIPREDIFLTTKVWNKDQGYERTLAAFETSLQKLGVDYVDLYLIHWPM---PDEDL- 114
Query: 442 PTDQSGKIQFSDVDYVDTWKAMEPLVKEGSGQ 537
Y+DTW+A+E L ++G +
Sbjct: 115 --------------YMDTWRALEQLYRDGKAK 132
>UniRef50_Q9ZBW7 Cluster: Putative oxidoreductase; n=2;
Actinomycetales|Rep: Putative oxidoreductase -
Streptomyces coelicolor
Length = 277
Score = 102 bits (245), Expect = 5e-21
Identities = 60/153 (39%), Positives = 81/153 (52%)
Frame = +1
Query: 70 SSVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAI 249
S VP + NN ++ P LG G W+ + AV A++ GYR ID A +YGNE+ G AI
Sbjct: 3 SKVPPIILNNGVEMPQLGFGVWQVPDDDAQTAVALALEAGYRSIDTAAIYGNEEGTGRAI 62
Query: 250 TSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKED 429
+ + REDLF+T+KLWN+ D A ++ L ++YLDLYLIHWP KE
Sbjct: 63 AAS----GLAREDLFVTTKLWNSDQGYDSTLRAFDTSMAKLGLEYLDLYLIHWPMPAKE- 117
Query: 430 GSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEG 528
YVDT+KA E L+ +G
Sbjct: 118 -----------------RYVDTYKAFEKLLADG 133
>UniRef50_A5AD50 Cluster: Putative uncharacterized protein; n=3;
Magnoliophyta|Rep: Putative uncharacterized protein -
Vitis vinifera (Grape)
Length = 304
Score = 102 bits (245), Expect = 5e-21
Identities = 47/81 (58%), Positives = 57/81 (70%)
Frame = +1
Query: 76 VPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 255
+ F + N K P +GLGTW+S PG V QAV AI +GYRHIDCA VYGNE+E+G +
Sbjct: 5 IRFFQLNTGAKMPSVGLGTWQSDPGLVGQAVAIAIKVGYRHIDCAQVYGNEEEIGIVLKK 64
Query: 256 KIKEGVVTREDLFITSKLWNT 318
+GVV REDL+ITSKLW T
Sbjct: 65 LFDDGVVKREDLWITSKLWCT 85
>UniRef50_Q9X0A2 Cluster: Oxidoreductase, aldo/keto reductase
family; n=21; Bacteria|Rep: Oxidoreductase, aldo/keto
reductase family - Thermotoga maritima
Length = 286
Score = 102 bits (244), Expect = 6e-21
Identities = 50/112 (44%), Positives = 72/112 (64%)
Frame = +1
Query: 76 VPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 255
VP V NN ++ PILG G ++ P + + V +AI +GYR ID A Y NE+ VG AI
Sbjct: 3 VPKVTLNNGVEMPILGYGVFQIPPEKTEECVYEAIKVGYRLIDTAASYMNEEGVGRAIKR 62
Query: 256 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 411
I EG+V RE+LF+T+KLW + + + A +++L L ++Y+DLYLIH P
Sbjct: 63 AIDEGIVRREELFVTTKLWVSDVGYESTKKAFEKSLKKLQLEYIDLYLIHQP 114
>UniRef50_Q5HR31 Cluster: Oxidoreductase, aldo/keto reductase
family; n=3; Staphylococcus|Rep: Oxidoreductase,
aldo/keto reductase family - Staphylococcus epidermidis
(strain ATCC 35984 / RP62A)
Length = 279
Score = 102 bits (244), Expect = 6e-21
Identities = 49/106 (46%), Positives = 65/106 (61%)
Frame = +1
Query: 94 NNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 273
NN P +GLG +K ++ + V+ A+D GYR D AY YGNEK +G A+ K
Sbjct: 9 NNGYPMPAVGLGVYKIADEQMEEVVRTALDAGYRAFDTAYFYGNEKALGSAL----KHSN 64
Query: 274 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 411
V R++LFITSKLWN + D ++LDNL + YLDL+LIHWP
Sbjct: 65 VERDELFITSKLWNDYQGYDQTIEYFNKSLDNLGLDYLDLFLIHWP 110
>UniRef50_Q01HB5 Cluster: OSIGBa0136O08-OSIGBa0153H12.9 protein;
n=4; Oryza sativa|Rep: OSIGBa0136O08-OSIGBa0153H12.9
protein - Oryza sativa (Rice)
Length = 337
Score = 100 bits (240), Expect = 2e-20
Identities = 61/153 (39%), Positives = 86/153 (56%), Gaps = 6/153 (3%)
Frame = +1
Query: 70 SSVPFVEFNNELKCPILGLGTWKSKP-GEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEA 246
++VP V N+ P+LG GT S P ++ + A+ +GYRH+D A VYG E VG A
Sbjct: 18 TAVPCVTLNSGHAMPVLGFGTGSSTPPADLAATIAHAVRLGYRHLDTAAVYGTEGAVGAA 77
Query: 247 ITSKIKEGVV-TREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAY- 420
+ ++ G V +R +LF+T+KL P V AL+E+L L + Y+DL+LIHWP A
Sbjct: 78 VAEAVRCGAVASRGELFVTTKLSMADAHPPRVVAALRESLSRLGLDYVDLFLIHWPVAIG 137
Query: 421 KED--GSLFPTDQS-GKIQFSDVDYVDTWKAME 510
K+D G L D S G + F D W+ ME
Sbjct: 138 KKDAAGELTWDDLSRGLVPF---DMEGVWRGME 167
>UniRef50_Q05KR9 Cluster: Benzil reductase; n=5; Bacillales|Rep:
Benzil reductase - Bacillus subtilis
Length = 276
Score = 100 bits (239), Expect = 2e-20
Identities = 63/149 (42%), Positives = 85/149 (57%), Gaps = 1/149 (0%)
Frame = +1
Query: 85 VEFNNELKCPILGLGTWKSKPG-EVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 261
V+ +N ++ P GLG +K + G E T++VK AI GYR ID A +Y NE+ VG I
Sbjct: 9 VKLHNGVEMPWFGLGVFKVENGNEATESVKAAIKNGYRSIDTAAIYKNEEGVGIGI---- 64
Query: 262 KEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLF 441
KE V RE+LFITSK+WN + A +++L+ L + YLDLYLIHWP
Sbjct: 65 KESGVAREELFITSKVWNEDQGYETTLAAFEKSLERLQLDYLDLYLIHWP---------- 114
Query: 442 PTDQSGKIQFSDVDYVDTWKAMEPLVKEG 528
GK + Y DTW+A+E L K+G
Sbjct: 115 -----GKDK-----YKDTWRALEKLYKDG 133
>UniRef50_Q03X85 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=1; Leuconostoc mesenteroides subsp.
mesenteroides ATCC 8293|Rep: Aldo/keto reductase of
diketogulonate reductase family - Leuconostoc
mesenteroides subsp. mesenteroides (strain ATCC 8293
/NCDO 523)
Length = 288
Score = 100 bits (239), Expect = 2e-20
Identities = 52/131 (39%), Positives = 71/131 (54%), Gaps = 2/131 (1%)
Frame = +1
Query: 82 FVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 261
F NN + P LG G ++ E QAV DAI+ GYR ID A VYGNE E G+ + I
Sbjct: 3 FKTLNNGAQMPQLGFGVFQIPAEETKQAVVDAINAGYRSIDTARVYGNEAETGQGVNEAI 62
Query: 262 KEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP--QAYKEDGS 435
VV RE+LF+T+KLW + + +GA+ ++L L Y DL L+H P Y +
Sbjct: 63 ANAVVAREELFLTTKLWLSEFSYEAAKGAIDDSLKKLGTDYADLILLHQPYGDVYGAYKA 122
Query: 436 LFPTDQSGKIQ 468
L GK++
Sbjct: 123 LAEAQADGKVK 133
>UniRef50_Q7NB44 Cluster: ARA1; n=3; Firmicutes|Rep: ARA1 -
Mycoplasma gallisepticum
Length = 289
Score = 99 bits (238), Expect = 3e-20
Identities = 58/158 (36%), Positives = 88/158 (55%), Gaps = 1/158 (0%)
Frame = +1
Query: 58 TVKMSSVPFVEFNNELKCPILGLGTWKSKPGEVT-QAVKDAIDIGYRHIDCAYVYGNEKE 234
T K+ + + N K P +G GT+K + G+ T +AVK A+++GYRH+DCA +Y N+
Sbjct: 5 TKKIKVMKYNLLANNYKMPSIGFGTYKLEDGKQTVEAVKTALEVGYRHLDCAEIYENQLS 64
Query: 235 VGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQ 414
V + I K V R+++FITSK+WN + + A + L +L+++YLDL LIHW
Sbjct: 65 VSQGI----KLSGVNRKEIFITSKIWNDDKGYESTKKAFHKILKDLDLEYLDLLLIHW-- 118
Query: 415 AYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEG 528
P + K + +V+ TWKAME EG
Sbjct: 119 ---------PIGKGFKDNWQEVN-AQTWKAMEEFYLEG 146
>UniRef50_A6WDZ5 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:
Aldo/keto reductase - Kineococcus radiotolerans SRS30216
Length = 343
Score = 99 bits (238), Expect = 3e-20
Identities = 56/155 (36%), Positives = 80/155 (51%), Gaps = 4/155 (2%)
Frame = +1
Query: 76 VPFVEFNNELKCPILGLGTWKS---KPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEA 246
VP E P +G+GT+ S P EV AV A+ GYR +DCA VYGNE +VGEA
Sbjct: 13 VPRRELRGGATVPAIGIGTFGSDRYSPAEVAAAVAGAVAAGYRLVDCAAVYGNEAQVGEA 72
Query: 247 ITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKE 426
+ + G V R++LF+ SK+WN H P ++ +L +L + +LD +HWP
Sbjct: 73 LAGAVAGG-VDRDELFVVSKVWNDAHAPADAVASVHRSLRDLRLDHLDAVFVHWPFPNHH 131
Query: 427 DGSLFPTDQSGKIQFSDVD-YVDTWKAMEPLVKEG 528
+ + + D D Y+ W A+E LV G
Sbjct: 132 PPMADTDARDPRARPYDHDAYLALWGALEGLVDSG 166
>UniRef50_Q968S3 Cluster: Aldoketoreductase-like protein; n=1;
Orconectes limosus|Rep: Aldoketoreductase-like protein -
Orconectes limosus (Spinycheek crayfish)
Length = 336
Score = 99.5 bits (237), Expect = 4e-20
Identities = 58/161 (36%), Positives = 87/161 (54%), Gaps = 7/161 (4%)
Frame = +1
Query: 67 MSSVPFVEFNNELKCPILGLGTW------KSKPGEVTQAVKDAIDIGYRHIDCAYVYGNE 228
M+ +P + N+ P++GLGT K VT ++ A++ GYRH D A YGNE
Sbjct: 8 MTKIPTILLNSGSHIPVMGLGTGSLGRNGKMSEEAVTAVLETALECGYRHFDSAAYYGNE 67
Query: 229 KEVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHW 408
+G+ + I EG V RE+LFIT+KL +R V LQ++LDNL + Y+DLYL+H+
Sbjct: 68 AIIGQVLRRWISEGKVKREELFITTKLPTRGNREKDVARFLQKSLDNLRLPYVDLYLVHY 127
Query: 409 PQAYKE-DGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEG 528
P + D D+ +D+ + W+AME + G
Sbjct: 128 PCGILDTDRERLSADEVTVDPTTDIHAI--WRAMEAQLAAG 166
>UniRef50_Q838E0 Cluster: Oxidoreductase, aldo/keto reductase
family; n=24; Bacilli|Rep: Oxidoreductase, aldo/keto
reductase family - Enterococcus faecalis (Streptococcus
faecalis)
Length = 279
Score = 99.1 bits (236), Expect = 6e-20
Identities = 51/123 (41%), Positives = 68/123 (55%), Gaps = 2/123 (1%)
Frame = +1
Query: 85 VEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 264
V NN K P +GLG ++ E + V++ I GYR ID A +YGNE G I + +
Sbjct: 9 VTLNNGTKIPGMGLGVFQIPDEETAKVVEEGIINGYRLIDTAQIYGNESGTGAGIKAGLA 68
Query: 265 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP--QAYKEDGSL 438
+ REDLF+TSK+WN D A ++L+ L + YLDLYLIHWP +YKE
Sbjct: 69 ATGLNREDLFVTSKVWNAHISYDETIQAFNDSLERLGLDYLDLYLIHWPGNNSYKESWQA 128
Query: 439 FPT 447
T
Sbjct: 129 LET 131
>UniRef50_Q9ZUJ6 Cluster: T2K10.1 protein; n=16; core
eudicotyledons|Rep: T2K10.1 protein - Arabidopsis
thaliana (Mouse-ear cress)
Length = 176
Score = 98.7 bits (235), Expect = 7e-20
Identities = 53/143 (37%), Positives = 79/143 (55%), Gaps = 4/143 (2%)
Frame = +1
Query: 112 PILGLGTWKS---KPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVV-T 279
P+LG GT S +P + + V +AI +GYRH D + Y E+ +GEA+ + G+V +
Sbjct: 22 PVLGFGTAASPLPEPTMLKETVIEAIKLGYRHFDTSPRYQTEEPIGEALAEAVSLGLVRS 81
Query: 280 REDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSG 459
R + F+T+KLW LV A++ +L NL + YLDLY+IHWP + K FP D+
Sbjct: 82 RSEFFVTTKLWCADAHGGLVVPAIKRSLKNLKLDYLDLYIIHWPVSSKPGKYKFPIDED- 140
Query: 460 KIQFSDVDYVDTWKAMEPLVKEG 528
F +D+ W ME + G
Sbjct: 141 --DFMPMDFEVVWSEMEECQRLG 161
>UniRef50_UPI00006CD296 Cluster: oxidoreductase, aldo/keto reductase
family protein; n=1; Tetrahymena thermophila SB210|Rep:
oxidoreductase, aldo/keto reductase family protein -
Tetrahymena thermophila SB210
Length = 295
Score = 97.5 bits (232), Expect = 2e-19
Identities = 55/148 (37%), Positives = 84/148 (56%), Gaps = 1/148 (0%)
Frame = +1
Query: 88 EFNNELKCPILGLGTWKS-KPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 264
E N K P+ GLGT+K E+ ++ A+D+GYRHID A +Y NEK++G+A+ K
Sbjct: 9 ELCNGSKLPVFGLGTYKVVSKEEMVTFLRTALDLGYRHIDTAIMYENEKQIGDALQEIYK 68
Query: 265 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 444
EG REDLF+ +KL++ ++ V ++++L NL Y+DLYL+H+ S P
Sbjct: 69 EGKYKREDLFLVTKLFS--NKNTKVEDQVRQSLQNLQTNYIDLYLLHY-------ASSPP 119
Query: 445 TDQSGKIQFSDVDYVDTWKAMEPLVKEG 528
TDQ + + W E LV++G
Sbjct: 120 TDQ---FELTHKPVFQVWAEFEELVQKG 144
>UniRef50_Q68ST9 Cluster: Reductase AKOR2; n=2; Pleurotus
djamor|Rep: Reductase AKOR2 - Pleurotus djamor
Length = 306
Score = 97.5 bits (232), Expect = 2e-19
Identities = 60/161 (37%), Positives = 88/161 (54%), Gaps = 7/161 (4%)
Frame = +1
Query: 67 MSSVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKD----AIDIGYRHIDCAYVYGNEKE 234
MS+ P + N + P L LG W E K+ A+ GYRHID A +Y EK
Sbjct: 1 MSAYPPIVLNTGARMPALALGGWAGLTEEERTQAKEWFLTALKSGYRHIDTAQIYYTEKS 60
Query: 235 VGEAITSKIKEGVVTREDLFITSKL-WNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 411
VG AI +E + RE+LFIT+KL WN R V + Q++L+NL +Y+DLYL+H+P
Sbjct: 61 VGNAI----RESGIPREELFITTKLPWNHHSR---VAESFQKSLENLGTEYIDLYLVHFP 113
Query: 412 Q-AYKEDGSLFPTDQSGKIQFSDVDYV-DTWKAMEPLVKEG 528
Q + ++ + FP + G I+ + + D W +E L+ G
Sbjct: 114 QRVFYDETTDFPRNPDGSIKVVNSPTLNDVWADVETLLDTG 154
>UniRef50_Q1RFP0 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=21; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase
A - Escherichia coli (strain UTI89 / UPEC)
Length = 294
Score = 97.1 bits (231), Expect = 2e-19
Identities = 50/113 (44%), Positives = 69/113 (61%), Gaps = 2/113 (1%)
Frame = +1
Query: 73 SVPFVEFNNELKCPILGLGTWKSKPGEVT-QAVKDAIDIGYRHIDCAYVYGNEKEVGEAI 249
+V F +N LK P++G G ++ +V Q+V +AI GYR ID A VYGNE VGEA+
Sbjct: 5 TVEFSVLSNNLKMPMMGFGVFQVTDKDVCKQSVLNAIRTGYRLIDTAAVYGNEDAVGEAV 64
Query: 250 TSKIKEGVVTREDLFITSKLW-NTFHRPDLVRGALQETLDNLNVQYLDLYLIH 405
I EG+ TRE+LFITSKLW D+ ++ +L ++Y DLYL+H
Sbjct: 65 REAISEGLCTREELFITSKLWVQDMLNQDIAAAGIEASLKKSGLEYFDLYLLH 117
>UniRef50_Q4PDR0 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 339
Score = 97.1 bits (231), Expect = 2e-19
Identities = 55/158 (34%), Positives = 88/158 (55%), Gaps = 11/158 (6%)
Frame = +1
Query: 70 SSVPFVEFNNELKCPILGLGTWKSKPG-----EVTQAVKDAIDIGYRHIDCAYVYGNEKE 234
+++P N K P +G+G W+ +PG E+ A+ AI +GYRH+D A Y NE E
Sbjct: 3 ANIPSFTLNTGAKLPSVGMGCWQGQPGPGRDNELVDALVRAIKVGYRHLDTATGYRNEAE 62
Query: 235 VGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQE---TLDNLNVQYLDLYLIH 405
VG+A+ ++ V R ++F+T+KL RP V +QE +L+ L + Y+DL+L+H
Sbjct: 63 VGQAV----RQSGVARSEIFVTTKL-----RPGGVHDVVQELENSLNELGIDYIDLWLLH 113
Query: 406 WPQAYKEDGSLFPTDQSGKIQFS---DVDYVDTWKAME 510
WPQ + +D F T +S ++ + +TW ME
Sbjct: 114 WPQGFTKDDGGFGTGESFGLEHQKHLGPTFNETWAKME 151
>UniRef50_Q8ZI40 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=74; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase
A - Yersinia pestis
Length = 277
Score = 96.7 bits (230), Expect = 3e-19
Identities = 52/122 (42%), Positives = 74/122 (60%), Gaps = 1/122 (0%)
Frame = +1
Query: 67 MSSVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEA 246
M+ P ++ + P LGLG W++ E AV A+++GYR ID A +Y NE+ VG+A
Sbjct: 1 MTMQPLIKLYDGRLMPQLGLGVWQASIQETELAVSKALEVGYRSIDTAAIYKNEEGVGKA 60
Query: 247 ITSKIKEGVVTREDLFITSKLWN-TFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYK 423
+K V R++LFIT+KLWN H P + AL+ +L L + Y+DLYLIHWP K
Sbjct: 61 ----LKAAAVARDELFITTKLWNDDQHNP---QQALETSLQKLQLDYVDLYLIHWPDP-K 112
Query: 424 ED 429
+D
Sbjct: 113 QD 114
>UniRef50_Q9A2X8 Cluster: Oxidoreductase, aldo/keto reductase
family; n=3; Caulobacter|Rep: Oxidoreductase, aldo/keto
reductase family - Caulobacter crescentus (Caulobacter
vibrioides)
Length = 279
Score = 95.1 bits (226), Expect = 9e-19
Identities = 48/114 (42%), Positives = 74/114 (64%), Gaps = 1/114 (0%)
Frame = +1
Query: 76 VPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 255
VP V + ++ P LG GTW+ + G V+ A++IGYRHID A +YGNE++VG A
Sbjct: 5 VPAVR-SGDVLMPALGFGTWQLENGTAVPLVEKALEIGYRHIDTAQIYGNERDVGAA--- 60
Query: 256 KIKEGVVTREDLFITSKLW-NTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQ 414
I+ V R+++F+T+K+W + F DL R A +++L+ L V +DL L+HWP+
Sbjct: 61 -IRNSGVKRDEIFLTTKVWIDQFADGDLQRSA-EKSLEKLGVDQVDLLLLHWPK 112
>UniRef50_Q4P4P1 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 322
Score = 95.1 bits (226), Expect = 9e-19
Identities = 48/110 (43%), Positives = 66/110 (60%), Gaps = 1/110 (0%)
Frame = +1
Query: 85 VEFNNELKCPILGLGTWKS-KPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 261
++ NN + P + LG +K+ G A K A D GYRHID A Y NE+ VG A+
Sbjct: 19 IKLNNGQEIPQVALGVYKAPNDGSTENACKWAFDAGYRHIDSAARYMNEESVGRALAEWT 78
Query: 262 KEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 411
KE V R ++FITSKLW+ H D A++++L LNV Y+D+YL+H P
Sbjct: 79 KENNVPRSEIFITSKLWDADH--DKAAAAIEDSLKKLNVDYMDMYLMHSP 126
>UniRef50_UPI00015B4912 Cluster: PREDICTED: similar to aldo-keto
reductase; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to aldo-keto reductase - Nasonia vitripennis
Length = 353
Score = 94.7 bits (225), Expect = 1e-18
Identities = 53/142 (37%), Positives = 81/142 (57%), Gaps = 3/142 (2%)
Frame = +1
Query: 112 PILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 291
PI+GLGT + + A++ G HID ++VY NE+ +G+ + +G RED+
Sbjct: 40 PIVGLGTHGLNEDVLETVLTGALEKGIGHIDTSFVYKNEETIGKVLKDWFAKGG-KREDI 98
Query: 292 FITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA--YKEDGSLFPTDQSGKI 465
F+TSKL + P+ V ++ +L+ L +QYLD+YLIH P A +KED T++ G +
Sbjct: 99 FVTSKLPYYDNHPESVEKYIKLSLEKLGLQYLDMYLIHAPFAVHHKEDSYELATNEDGSV 158
Query: 466 QF-SDVDYVDTWKAMEPLVKEG 528
+ D + WK ME VKEG
Sbjct: 159 VLDTQTDPIAVWKEMEKQVKEG 180
>UniRef50_A4FEB9 Cluster: 2,5-diketo-D-gluconic acid reductase; n=1;
Saccharopolyspora erythraea NRRL 2338|Rep:
2,5-diketo-D-gluconic acid reductase - Saccharopolyspora
erythraea (strain NRRL 23338)
Length = 159
Score = 94.7 bits (225), Expect = 1e-18
Identities = 49/115 (42%), Positives = 66/115 (57%)
Frame = +1
Query: 67 MSSVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEA 246
M+SVP V NN ++ P LG G ++ E AV A++ GYR ID A YGNE VG A
Sbjct: 1 MTSVPTVTLNNGVEMPQLGYGVFQVPEDETAAAVGAALEAGYRSIDTAAAYGNEAAVGRA 60
Query: 247 ITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 411
+ + R++LF+T+KLWN D A +L+ L + +LDLYLIHWP
Sbjct: 61 LAG----SGLARDELFVTTKLWNADQGYDNALRAFDTSLELLGLDHLDLYLIHWP 111
>UniRef50_A0JRJ3 Cluster: 2,5-didehydrogluconate reductase; n=3;
Actinobacteria (class)|Rep: 2,5-didehydrogluconate
reductase - Arthrobacter sp. (strain FB24)
Length = 276
Score = 94.7 bits (225), Expect = 1e-18
Identities = 50/121 (41%), Positives = 68/121 (56%)
Frame = +1
Query: 67 MSSVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEA 246
M+ P +E N+ + P +GLGTW +V AV +A++ GYRHID A YGNEK VG
Sbjct: 1 MALSPVIELNDGHRIPQIGLGTWPLDDHQVAAAVVNAVEGGYRHIDTAVKYGNEKGVGNG 60
Query: 247 ITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKE 426
I S + R +LFIT+KL F D L +L L + Y+DL LIHWP ++
Sbjct: 61 IRS----SGLDRSELFITTKLDGEFQGQDRAVAGLDGSLKRLGLDYVDLLLIHWPLPRRD 116
Query: 427 D 429
+
Sbjct: 117 E 117
>UniRef50_Q8ET73 Cluster: 2,5-diketo-D-gluconate reductase; n=12;
Bacteria|Rep: 2,5-diketo-D-gluconate reductase -
Oceanobacillus iheyensis
Length = 280
Score = 94.3 bits (224), Expect = 2e-18
Identities = 49/120 (40%), Positives = 68/120 (56%)
Frame = +1
Query: 67 MSSVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEA 246
++ +P V ++ L P +G GT++ + QA+ +AID GYR ID AY Y NE VGEA
Sbjct: 2 VNQIPNVTLHDGLTIPKVGFGTYRLNGNDGVQAINNAIDHGYRLIDTAYNYENEGTVGEA 61
Query: 247 ITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKE 426
++ RE L ITSKL +H D +QE+L N+ Y DLYLIHWP ++
Sbjct: 62 ----VRRSSTPREQLLITSKLPGRYHHYDKAVTTIQESLYRANLDYYDLYLIHWPNPIQD 117
>UniRef50_A2UAH0 Cluster: Aldo/keto reductase; n=1; Bacillus
coagulans 36D1|Rep: Aldo/keto reductase - Bacillus
coagulans 36D1
Length = 273
Score = 94.3 bits (224), Expect = 2e-18
Identities = 54/145 (37%), Positives = 77/145 (53%), Gaps = 1/145 (0%)
Frame = +1
Query: 97 NELKCPILGLGTWKSKPGEVT-QAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 273
N + P +GLGTW+ GE T AV A+ GYRHID AY Y NE+ VG+A+ ++
Sbjct: 12 NGVAIPKIGLGTWQVPNGETTYHAVSFALKNGYRHIDTAYAYHNEESVGKAV----RDSG 67
Query: 274 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQ 453
+ R D+F+TSKL D ET+ N ++ LDLYLIH P + E G+ + +
Sbjct: 68 IDRRDIFVTSKLPAEIKSYDKALKTFDETMGNFGLEQLDLYLIHAPWPWSEKGADYTKEN 127
Query: 454 SGKIQFSDVDYVDTWKAMEPLVKEG 528
++ WKAME + + G
Sbjct: 128 -----------IEVWKAMEEIYESG 141
>UniRef50_Q7WSY4 Cluster: Putative aldo-keto reductase; n=1;
Propionibacterium freudenreichii subsp. shermanii|Rep:
Putative aldo-keto reductase - Propionibacterium
freudenreichii subsp. shermanii
Length = 280
Score = 93.5 bits (222), Expect = 3e-18
Identities = 45/117 (38%), Positives = 69/117 (58%)
Frame = +1
Query: 61 VKMSSVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVG 240
+ + P VE + + P+LG+GTW K E AV AI+ GYR +D A YGNE+ VG
Sbjct: 3 IPTTPTPTVELSGGTRMPMLGMGTWPLKGEECRAAVASAIEQGYRLVDTAEAYGNEEAVG 62
Query: 241 EAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 411
+A ++E R ++F+T+K +H V AL+ +L+ L + Y+DL+L+HWP
Sbjct: 63 KA----VREAGPDRAEIFVTTKFSKQWHSRKGVHEALEHSLERLGLDYVDLFLMHWP 115
>UniRef50_Q89JN4 Cluster: Oxidoreductase; n=8; Rhizobiales|Rep:
Oxidoreductase - Bradyrhizobium japonicum
Length = 272
Score = 93.1 bits (221), Expect = 4e-18
Identities = 43/113 (38%), Positives = 70/113 (61%)
Frame = +1
Query: 82 FVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 261
FVE N + P +GLGTW+ + V+ A+ +GYRHID A VY NE+EVG+ +
Sbjct: 3 FVEANGA-RIPAIGLGTWELSGRPCARVVEQALRLGYRHIDTAQVYDNEREVGDG----V 57
Query: 262 KEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAY 420
+ V R+D+F+T+K+W P+ + +++E+L L + +DL L+HWP ++
Sbjct: 58 RASGVRRDDVFLTTKVWTNHFAPNDLERSVKESLARLRLPSVDLLLLHWPNSH 110
>UniRef50_Q5FLI5 Cluster: Aldehyde reductase; n=2; Bacteria|Rep:
Aldehyde reductase - Lactobacillus acidophilus
Length = 278
Score = 93.1 bits (221), Expect = 4e-18
Identities = 47/111 (42%), Positives = 67/111 (60%), Gaps = 1/111 (0%)
Frame = +1
Query: 82 FVEFNNELKCPILGLGTWKSKP-GEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSK 258
FV NN +K P LG G ++ + Q V+D +++GYR +D A +YGNE+ VG+AI
Sbjct: 4 FVTLNNGIKMPRLGFGVYQIDDLAQAQQVVEDGLEVGYRLVDTAQIYGNEQAVGDAI--- 60
Query: 259 IKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 411
K V RED+FITSK+W + D A +++ L + Y+DLYLIH P
Sbjct: 61 -KHSNVPREDIFITSKIWVDDYGYDNTLKAFDDSMKKLQLDYIDLYLIHKP 110
>UniRef50_UPI00015B5BD7 Cluster: PREDICTED: similar to aldo-keto
reductase; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to aldo-keto reductase - Nasonia vitripennis
Length = 310
Score = 92.7 bits (220), Expect = 5e-18
Identities = 47/113 (41%), Positives = 74/113 (65%), Gaps = 2/113 (1%)
Frame = +1
Query: 85 VEFNNELKCPILGLGTWKSKPGEVTQAVKD-AIDIGYRHIDCAYVYGNEKEVGEAITSKI 261
+ NN P++G+GT+K + EV + V D + +G+R ID A VY NE+++G A+ +
Sbjct: 26 LRLNNGYDMPLVGIGTYKVRGREVIKRVIDESFAVGFRSIDTAVVYRNEEDIGLALKELL 85
Query: 262 KEGVVTREDLFITSKLWNTFH-RPDLVRGALQETLDNLNVQYLDLYLIHWPQA 417
+ + RED+FITSKL + + PD +R +++++L L+ YLDLYLIHWP A
Sbjct: 86 PKYNLKREDIFITSKLSPSDNGDPDKIRKSVEDSLKALDTSYLDLYLIHWPGA 138
>UniRef50_Q7VG53 Cluster: Aldo-keto reductase; n=28; Bacteria|Rep:
Aldo-keto reductase - Helicobacter hepaticus
Length = 292
Score = 92.7 bits (220), Expect = 5e-18
Identities = 50/114 (43%), Positives = 67/114 (58%), Gaps = 1/114 (0%)
Frame = +1
Query: 82 FVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAI-TSK 258
F NN K P LGLGTW+ V AV++A +GYRHID A YGNE+ VGEA+ SK
Sbjct: 14 FFTLNNGNKIPKLGLGTWRIDDNVVEAAVREAFKVGYRHIDTAQAYGNERGVGEAVRKSK 73
Query: 259 IKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAY 420
IK RE+LFITSK+ + ++ +L + + ++DL LIH PQ +
Sbjct: 74 IK-----REELFITSKIRAEYKDYKSASASIDTSLKTMKLDFIDLMLIHSPQPW 122
>UniRef50_A6NPD6 Cluster: Putative uncharacterized protein; n=3;
Bacteria|Rep: Putative uncharacterized protein -
Bacteroides capillosus ATCC 29799
Length = 287
Score = 92.7 bits (220), Expect = 5e-18
Identities = 47/107 (43%), Positives = 62/107 (57%)
Frame = +1
Query: 94 NNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 273
+N L P +G GT+K+ G+ + + +AI GYRH D A YG E +G+A+ E
Sbjct: 11 SNGLSIPAVGFGTYKTGDGD-SAVLSNAIAQGYRHFDTASFYGTETALGQAVA----ESD 65
Query: 274 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQ 414
+ RED F+TSKLW T D A TL+ L YLDLYLIHWP+
Sbjct: 66 IPREDFFLTSKLWKTEMGYDAALRAFDATLERLGTDYLDLYLIHWPR 112
>UniRef50_A3UJS6 Cluster: Oxidoreductase; n=3;
Alphaproteobacteria|Rep: Oxidoreductase - Oceanicaulis
alexandrii HTCC2633
Length = 275
Score = 92.7 bits (220), Expect = 5e-18
Identities = 43/105 (40%), Positives = 62/105 (59%)
Frame = +1
Query: 97 NELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVV 276
N P LG GTW+ + + + V A+ GYRHID A +YGNE VG+ K+ V
Sbjct: 8 NGADIPKLGFGTWQLEDEDAARGVATALKTGYRHIDTAQIYGNEAAVGDGW----KQSGV 63
Query: 277 TREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 411
RED F+T+K+W R ++ +++E+LD L Y+DL L+HWP
Sbjct: 64 KREDFFLTTKVWRDKFRDGDLQASVKESLDKLKTDYVDLLLLHWP 108
>UniRef50_Q88TV9 Cluster: Oxidoreductase; n=4; Lactobacillus|Rep:
Oxidoreductase - Lactobacillus plantarum
Length = 288
Score = 92.3 bits (219), Expect = 6e-18
Identities = 48/116 (41%), Positives = 68/116 (58%), Gaps = 1/116 (0%)
Frame = +1
Query: 67 MSSVPFVEFNNELKCPILGLGTWK-SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGE 243
M+ P + N+ P +G GT++ G QAVK+A+ IGYRHID A Y NE EVG+
Sbjct: 1 MTKTPTITLNDGRAIPAIGFGTFQIPDDGSTYQAVKEALVIGYRHIDTAVAYFNEDEVGQ 60
Query: 244 AITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 411
A IK+ + R+ +++TSKLW + D A+ +L L + Y+DLYLIH P
Sbjct: 61 A----IKDSGIPRDQIWVTSKLWLQDYGFDAASRAIDRSLTKLRLDYIDLYLIHQP 112
>UniRef50_A3VHZ9 Cluster: Oxidoreductase; n=1; Rhodobacterales
bacterium HTCC2654|Rep: Oxidoreductase - Rhodobacterales
bacterium HTCC2654
Length = 278
Score = 91.9 bits (218), Expect = 9e-18
Identities = 46/116 (39%), Positives = 68/116 (58%)
Frame = +1
Query: 64 KMSSVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGE 243
++ P V N ++ P LGLGTW E +AV AI+ GYR ID A Y NE VG+
Sbjct: 3 RIDPAPTVTLANGVEMPQLGLGTWPMTDDEAAKAVATAIETGYRLIDTAENYKNETGVGQ 62
Query: 244 AITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 411
I++ V R+++F+T+K+ +H D R A + +L+ L + Y+DL+LIHWP
Sbjct: 63 G----IRDAGVARDEVFLTTKMNKQWHSVDGARRACEASLERLGLDYIDLFLIHWP 114
>UniRef50_A3VRL4 Cluster: Putative uncharacterized protein; n=1;
Parvularcula bermudensis HTCC2503|Rep: Putative
uncharacterized protein - Parvularcula bermudensis
HTCC2503
Length = 278
Score = 91.5 bits (217), Expect = 1e-17
Identities = 42/100 (42%), Positives = 64/100 (64%)
Frame = +1
Query: 112 PILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 291
P LG GTW+ + + + + AI+ GYRHID A +Y NEK+VGE IK+ + R++L
Sbjct: 12 PRLGFGTWQLEGEDARTSTRTAIETGYRHIDGAAIYKNEKKVGEG----IKDSGIPRDEL 67
Query: 292 FITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 411
F+T+K+WN + A+ E+LD L + Y++L L+HWP
Sbjct: 68 FVTTKIWNEDIQKGRHSEAVDESLDRLGLDYVNLILLHWP 107
>UniRef50_A0JRJ6 Cluster: Aldo/keto reductase; n=2;
Micrococcineae|Rep: Aldo/keto reductase - Arthrobacter
sp. (strain FB24)
Length = 281
Score = 91.1 bits (216), Expect = 1e-17
Identities = 48/116 (41%), Positives = 69/116 (59%)
Frame = +1
Query: 64 KMSSVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGE 243
+ +++P + NN +K P LG G ++ P E + V+DA++ GYRHID A Y NE VG
Sbjct: 5 QQNTIPQLTLNNGVKIPQLGFGVFQVPPEETQRIVEDALEAGYRHIDTAAAYRNEAGVGA 64
Query: 244 AITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 411
AI++ + RED+FIT+KL N A Q + L V+++DLYLIHWP
Sbjct: 65 AISA----SGIPREDIFITTKLRN--GEQGNAHEAFQNSRKALGVEFVDLYLIHWP 114
>UniRef50_Q7G764 Cluster: Probable NAD(P)H-dependent oxidoreductase
1; n=32; Eukaryota|Rep: Probable NAD(P)H-dependent
oxidoreductase 1 - Oryza sativa subsp. japonica (Rice)
Length = 321
Score = 91.1 bits (216), Expect = 1e-17
Identities = 51/153 (33%), Positives = 84/153 (54%), Gaps = 5/153 (3%)
Frame = +1
Query: 67 MSSVPFVEFNNELKC-PILGLGTWK---SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKE 234
M+++P V + ++ P +G+GT + + T A+ AI++GYRH D A +Y E
Sbjct: 1 MATIPEVPASELIQTMPRVGMGTAAFPFTSSEDTTAAMLRAIELGYRHFDTARIYATEGC 60
Query: 235 VGEAITSKIKEGVV-TREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 411
VGEA+ ++ G++ +R D+F+TSK+W + V A +ETL NL + Y+DL L+HWP
Sbjct: 61 VGEAVAEAVRRGLIASRADVFVTSKIWCSDLHAGRVVPAARETLRNLGMDYVDLLLVHWP 120
Query: 412 QAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAME 510
+ FP + ++ D W+ ME
Sbjct: 121 VSLTPGNYDFPFPK--EVILPSFDMEGVWRGME 151
>UniRef50_Q02198 Cluster: Morphine 6-dehydrogenase; n=5;
Bacteria|Rep: Morphine 6-dehydrogenase - Pseudomonas
putida
Length = 296
Score = 91.1 bits (216), Expect = 1e-17
Identities = 45/111 (40%), Positives = 63/111 (56%)
Frame = +1
Query: 79 PFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSK 258
P + NN +K P LGLG + + E A+ AI GYR ID A Y NE +VGE
Sbjct: 6 PLINLNNGVKMPALGLGVFAASAEETASAIASAISSGYRLIDTARSYNNEAQVGEG---- 61
Query: 259 IKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 411
I+ V R ++F+T+KL+N + + A E+L L + Y+DLYL+HWP
Sbjct: 62 IRNSGVDRAEMFVTTKLFNCDYGYERALRAFDESLGRLGLDYVDLYLLHWP 112
>UniRef50_Q5XJM7 Cluster: Zgc:101765; n=5; Eumetazoa|Rep: Zgc:101765
- Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 288
Score = 90.6 bits (215), Expect = 2e-17
Identities = 48/112 (42%), Positives = 69/112 (61%), Gaps = 1/112 (0%)
Frame = +1
Query: 79 PFVEFNNELKCPILGLGTWKSKPGEVT-QAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 255
P V NN+++ P+LGLGT++ + E T AV A+ GYR D A VY NE +G A+
Sbjct: 6 PSVLLNNDIQMPLLGLGTFRLQGQEDTYSAVDAALKAGYRAFDTAAVYRNEAHLGHALRC 65
Query: 256 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 411
+ + ++RED+FITSKL + R Q++L+ L + Y+DLYLIHWP
Sbjct: 66 LLPKHGLSREDVFITSKL-GPKDQGSKARNGCQKSLEQLGLGYIDLYLIHWP 116
>UniRef50_Q1VRG6 Cluster: YvgN; n=1; Psychroflexus torquis ATCC
700755|Rep: YvgN - Psychroflexus torquis ATCC 700755
Length = 280
Score = 90.6 bits (215), Expect = 2e-17
Identities = 57/148 (38%), Positives = 84/148 (56%), Gaps = 3/148 (2%)
Frame = +1
Query: 94 NNELKCPILGLGTWKSKPGEVTQAV-KDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEG 270
N+ + PI+G GT+K+ E +++ K A+ +GYR ID +Y NE+ VG+AI ++ G
Sbjct: 6 NDGNRIPIVGFGTYKANEEEGIKSIQKSALTLGYRLIDTVAIYQNEEAVGKAIKAR---G 62
Query: 271 VVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTD 450
V+ RE++F+T+KLW R AL E+L L++ Y+DLYLIHWP
Sbjct: 63 VL-REEIFVTTKLWRENLGYKQTRIALDESLRKLDLNYIDLYLIHWP------------- 108
Query: 451 QSGKIQFSD--VDYVDTWKAMEPLVKEG 528
+ I + D DTW+AME L EG
Sbjct: 109 -ANAINYKDWQKTNADTWRAMEELQAEG 135
>UniRef50_A0JX62 Cluster: 2,5-didehydrogluconate reductase; n=9;
Bacteria|Rep: 2,5-didehydrogluconate reductase -
Arthrobacter sp. (strain FB24)
Length = 291
Score = 90.6 bits (215), Expect = 2e-17
Identities = 50/130 (38%), Positives = 69/130 (53%), Gaps = 13/130 (10%)
Frame = +1
Query: 67 MSSVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEA 246
M + P + NN + LG G +K P + V A++ GYRH D A +YGNE VG+A
Sbjct: 1 MKNSPRLSLNNGVLIDQLGFGLYKVPPADAAGLVTMALEAGYRHFDTAAMYGNETGVGKA 60
Query: 247 IT-------------SKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYL 387
I S ++REDLF+T+K+WN H D A ++ NL ++Y+
Sbjct: 61 IGALAGFAGGGPAGGSGEAAPSLSREDLFVTTKVWNDDHGYDATMRAFDTSMSNLGMEYV 120
Query: 388 DLYLIHWPQA 417
DLYLIHWP A
Sbjct: 121 DLYLIHWPCA 130
>UniRef50_A7CUW0 Cluster: 2,5-didehydrogluconate reductase; n=6;
Bacteria|Rep: 2,5-didehydrogluconate reductase -
Opitutaceae bacterium TAV2
Length = 334
Score = 90.2 bits (214), Expect = 3e-17
Identities = 44/115 (38%), Positives = 68/115 (59%)
Frame = +1
Query: 67 MSSVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEA 246
M +P + ++ P LGLG W+ ++ A + GYR ID A +YGNE+ VG A
Sbjct: 56 MRMIPTLPLSDGTSIPQLGLGVWQMPDDGAGVPIQAAFNAGYRAIDTAPIYGNEEGVGRA 115
Query: 247 ITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 411
I + + R++L+IT+K+WN+ D A++E+L L ++Y+DLYLIHWP
Sbjct: 116 I----RASGLPRKELYITTKVWNSAQGYDSTLRAVRESLGRLQLEYVDLYLIHWP 166
>UniRef50_A4YQ04 Cluster: 2,5-diketo-D-gluconate reductase B; n=15;
Proteobacteria|Rep: 2,5-diketo-D-gluconate reductase B -
Bradyrhizobium sp. (strain ORS278)
Length = 273
Score = 90.2 bits (214), Expect = 3e-17
Identities = 42/103 (40%), Positives = 63/103 (61%)
Frame = +1
Query: 103 LKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTR 282
++ P LGLGT++ + AV+ A+ +GYRHID A +Y NE +G A+ + + R
Sbjct: 9 VRLPKLGLGTFRMQGTVCRDAVESALALGYRHIDTAEMYANEDAIGAALAA----AQIAR 64
Query: 283 EDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 411
EDL +T+K+W PD +R A +L L + ++DLYLIHWP
Sbjct: 65 EDLHVTTKVWPENLAPDAIRRAFDTSLKKLRLDFVDLYLIHWP 107
>UniRef50_Q0SFM4 Cluster: Probable 2,5-didehydrogluconate reductase;
n=1; Rhodococcus sp. RHA1|Rep: Probable
2,5-didehydrogluconate reductase - Rhodococcus sp.
(strain RHA1)
Length = 265
Score = 89.8 bits (213), Expect = 3e-17
Identities = 47/100 (47%), Positives = 62/100 (62%)
Frame = +1
Query: 112 PILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 291
P LGLGTW + T+AV I+ GYR ID A +Y NE VG A+ E V RE+L
Sbjct: 5 PPLGLGTWPLTGPDATRAVLSGIEAGYRLIDTATIYDNEDAVGVALA----ECGVPREEL 60
Query: 292 FITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 411
F+T+KL + H +RGA++ +L NL + LDL+LIHWP
Sbjct: 61 FVTTKLRGSDHVSGDIRGAVERSLKNLGLDRLDLFLIHWP 100
>UniRef50_A7ALH6 Cluster: Putative uncharacterized protein; n=1;
Parabacteroides merdae ATCC 43184|Rep: Putative
uncharacterized protein - Parabacteroides merdae ATCC
43184
Length = 301
Score = 89.8 bits (213), Expect = 3e-17
Identities = 52/116 (44%), Positives = 71/116 (61%)
Frame = +1
Query: 64 KMSSVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGE 243
+M+ VP V+ NN ++ P LG+GT+ K + V AI +G+R ID A YGNEKEVGE
Sbjct: 25 EMNKVPTVKLNNGMEMPQLGVGTFLVKDN-AAERVCHAIKVGFRLIDTAQGYGNEKEVGE 83
Query: 244 AITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 411
I + G+ RE LFIT+K+ R VR +L ++L +L Y+DL LIHWP
Sbjct: 84 GIC---RSGIDRRE-LFITTKVNTMEMRGGTVRQSLDKSLADLGTDYIDLVLIHWP 135
>UniRef50_A5ZYE6 Cluster: Putative uncharacterized protein; n=1;
Ruminococcus obeum ATCC 29174|Rep: Putative
uncharacterized protein - Ruminococcus obeum ATCC 29174
Length = 263
Score = 89.8 bits (213), Expect = 3e-17
Identities = 49/101 (48%), Positives = 62/101 (61%), Gaps = 1/101 (0%)
Frame = +1
Query: 112 PILGLGTWKSKPG-EVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 288
P+LGLG +K+ E A+ A+ GYR +D A Y NE+ VG I K GV R+D
Sbjct: 2 PLLGLGLYKTTDAVEAEDAIAAAVQNGYRLLDTASAYKNEEFVGCGIA---KCGV-PRKD 57
Query: 289 LFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 411
LFIT+K+WN R V GA Q +LD L + Y+DLYLIHWP
Sbjct: 58 LFITTKIWNNAQRLGDVEGAFQRSLDRLGLDYIDLYLIHWP 98
>UniRef50_Q7G765 Cluster: Probable NAD(P)H-dependent oxidoreductase
2; n=6; Magnoliophyta|Rep: Probable NAD(P)H-dependent
oxidoreductase 2 - Oryza sativa subsp. japonica (Rice)
Length = 322
Score = 89.8 bits (213), Expect = 3e-17
Identities = 55/153 (35%), Positives = 82/153 (53%), Gaps = 5/153 (3%)
Frame = +1
Query: 67 MSSVPFVEFNNELKC-PILGLGTWK---SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKE 234
M+++P V + L P +G+GT + E T A+ AI++GYRH D A +Y E
Sbjct: 3 MATIPEVPASALLPTMPRIGMGTAAFPFTSSEETTAALLRAIELGYRHFDTARLYATEGC 62
Query: 235 VGEAITSKIKEGVV-TREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 411
V EA+ ++ G+V +R D+F+TSKLW + V A +ETL NL + Y+DL L+HWP
Sbjct: 63 VSEAVAEAVRRGLVASRADVFVTSKLWCSDLHAGRVVPAARETLRNLGMDYVDLLLVHWP 122
Query: 412 QAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAME 510
FP + D++ V W+ ME
Sbjct: 123 ATVAPGSYDFPFPKEEMAPAFDMEGV--WRGME 153
>UniRef50_UPI00006CCCD7 Cluster: oxidoreductase, aldo/keto reductase
family protein; n=1; Tetrahymena thermophila SB210|Rep:
oxidoreductase, aldo/keto reductase family protein -
Tetrahymena thermophila SB210
Length = 323
Score = 89.4 bits (212), Expect = 5e-17
Identities = 50/130 (38%), Positives = 74/130 (56%), Gaps = 9/130 (6%)
Frame = +1
Query: 76 VPFVEFNNELKCPILGLGTW------KSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEV 237
+ +V+ NN K P+LGLGT + E+T + +A+D GYR+ D A Y NE E+
Sbjct: 12 IKYVQLNNGYKMPLLGLGTQPYDIVTRVTVEEMTTLLSNALDFGYRNFDTAKQYRNEVEI 71
Query: 238 GEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHW--- 408
G+A + ++G RED+FIT+KL+ F ++ +Q +LD L Y+DLYLI W
Sbjct: 72 GQAFQNIFQQGKYKREDVFITTKLF-PFKIEKKIKEVVQNSLDQLQTSYIDLYLIQWSFT 130
Query: 409 PQAYKEDGSL 438
P DGS+
Sbjct: 131 PVLTNFDGSV 140
>UniRef50_Q929C8 Cluster: Lin2349 protein; n=12; Listeria|Rep:
Lin2349 protein - Listeria innocua
Length = 294
Score = 89.4 bits (212), Expect = 5e-17
Identities = 50/105 (47%), Positives = 64/105 (60%), Gaps = 1/105 (0%)
Frame = +1
Query: 112 PILGLGTWKSKPGE-VTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 288
P +GLG ++ E + AV+ AI++GYR D A VY NE VG+AI + V RE+
Sbjct: 18 PYIGLGVFQVTEQEFIAGAVEKAIEVGYRLFDTAAVYNNEAIVGQAIL----DSAVPREE 73
Query: 289 LFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYK 423
LFI+SK+WN D A + TL NL + YLDLYLIHWP A K
Sbjct: 74 LFISSKVWNGDLGYDETLFAFERTLRNLKLDYLDLYLIHWPVAGK 118
>UniRef50_Q15NA5 Cluster: Aldo/keto reductase; n=2;
Gammaproteobacteria|Rep: Aldo/keto reductase -
Pseudoalteromonas atlantica (strain T6c / BAA-1087)
Length = 273
Score = 89.0 bits (211), Expect = 6e-17
Identities = 42/100 (42%), Positives = 63/100 (63%)
Frame = +1
Query: 112 PILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 291
P G GT++ K + AV++A+D+GYRHID A Y NE EVG+AI++ ++R +L
Sbjct: 12 PTPGFGTYRLKGDDAKLAVENALDVGYRHIDTAQAYENEAEVGDAISA----SKISRGEL 67
Query: 292 FITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 411
F+T+K+W D ++Q +L LN Y+DL L+HWP
Sbjct: 68 FVTTKVWFDNLSADKFITSVQNSLTQLNTDYVDLLLVHWP 107
>UniRef50_Q568D7 Cluster: Zgc:110366; n=7; Euteleostomi|Rep:
Zgc:110366 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 289
Score = 88.6 bits (210), Expect = 8e-17
Identities = 59/153 (38%), Positives = 85/153 (55%), Gaps = 1/153 (0%)
Frame = +1
Query: 73 SVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAI-DIGYRHIDCAYVYGNEKEVGEAI 249
S P V +N L PILGLGT G +AV A+ + G RHID A YG E+ +G+A+
Sbjct: 12 SCPAVPLHNGLNIPILGLGT-SHYGGYSHEAVLYALQECGIRHIDTAKRYGCEEALGKAV 70
Query: 250 TSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKED 429
T E V RE+L++T+KLW + + A +++ L V YLDLYL+HWP
Sbjct: 71 T----ESGVQREELWVTTKLWPGDYGYQSTKQACRDSRARLGVDYLDLYLMHWPD----- 121
Query: 430 GSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEG 528
S+ P S +++ ++TW+A+E L EG
Sbjct: 122 -SMVPGRSSQEVR------LETWRALEELYDEG 147
>UniRef50_Q4PHK0 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 355
Score = 88.6 bits (210), Expect = 8e-17
Identities = 60/176 (34%), Positives = 84/176 (47%), Gaps = 29/176 (16%)
Frame = +1
Query: 88 EFNNELKCPILGLGTWKSKPGEVTQAVKDAID-----------------IGYRHI----- 201
+ N + P++GLGTW+S PGEV +AV+ AI +GY +
Sbjct: 15 KLNTGAEIPVIGLGTWQSAPGEVAKAVESAIKAGYRHIVSMLTSLLTLTLGYVALHPLYI 74
Query: 202 -----DCAYVYGNEKEVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLD 366
D A++YGNE EVG+ I K V R +LF+T+K+W T+HR L E+L
Sbjct: 75 PFLAKDAAWIYGNENEVGQGI----KASGVPRSELFVTTKIWCTYHRQP--EACLDESLQ 128
Query: 367 NLNVQYLDLYLIHWP-QAYKEDGSLFPTDQSGKIQFS-DVDYVDTWKAMEPLVKEG 528
L + Y+DL L+HWP K P ++ G D TW+ ME L G
Sbjct: 129 RLGLDYVDLLLVHWPVPLVKRGDEKIPLNEDGSRAIDRDWSPEQTWELMEKLPATG 184
>UniRef50_Q5UX52 Cluster: Oxidoreductase aldo/keto reductase family;
n=1; Haloarcula marismortui|Rep: Oxidoreductase
aldo/keto reductase family - Haloarcula marismortui
(Halobacterium marismortui)
Length = 274
Score = 88.6 bits (210), Expect = 8e-17
Identities = 44/100 (44%), Positives = 61/100 (61%)
Frame = +1
Query: 112 PILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 291
P LGLGTW+ + V+ A+ +GYRHID A YGNE++VG + + V RED+
Sbjct: 12 PALGLGTWQLTGQSCRETVETALGMGYRHIDTAQAYGNERQVGLGMDA----AAVDREDV 67
Query: 292 FITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 411
F+T+KL + VR + +E+L+ L YLDL LIHWP
Sbjct: 68 FLTTKLDGSNRDERSVRRSTRESLNKLGTDYLDLLLIHWP 107
>UniRef50_Q5BLA6 Cluster: Zgc:110782; n=2; Danio rerio|Rep:
Zgc:110782 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 287
Score = 88.2 bits (209), Expect = 1e-16
Identities = 47/113 (41%), Positives = 69/113 (61%), Gaps = 1/113 (0%)
Frame = +1
Query: 76 VPFVEFNNELKCPILGLGTWKSKPGE-VTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAIT 252
VP V + + P+LGLGT+K + E + Q+V A+ GYR D A VYGNE +G+ +
Sbjct: 3 VPSVRLMSGTQMPLLGLGTYKLQDHEQLKQSVSCALQAGYRAFDTAAVYGNEAHLGQVLK 62
Query: 253 SKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 411
+ + + RED+FI SKL + H G L+ +L+ L+ +Y+DLYLIHWP
Sbjct: 63 ELLPKYGLIREDVFIISKLAPSDHGLRAKEGCLR-SLEQLDCEYIDLYLIHWP 114
>UniRef50_Q4V008 Cluster: Oxidoreductase; n=4; Proteobacteria|Rep:
Oxidoreductase - Xanthomonas campestris pv. campestris
(strain 8004)
Length = 267
Score = 88.2 bits (209), Expect = 1e-16
Identities = 43/100 (43%), Positives = 63/100 (63%)
Frame = +1
Query: 112 PILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 291
P GLGT++ K V +V++A+ +GYR ID A +Y NE +VG+AI + V R+ L
Sbjct: 4 PAFGLGTFRLKDQVVIDSVRNALALGYRAIDTAQIYDNEAQVGQAIA----DAGVPRDQL 59
Query: 292 FITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 411
F+T+K+W D ++ +LQE+L L Y+DL LIHWP
Sbjct: 60 FVTTKIWVDRFSRDTLQPSLQESLRKLGTDYVDLTLIHWP 99
>UniRef50_Q14LU6 Cluster: Putative aldo/keto reductase
oxidoreductase protein; n=1; Spiroplasma citri|Rep:
Putative aldo/keto reductase oxidoreductase protein -
Spiroplasma citri
Length = 138
Score = 88.2 bits (209), Expect = 1e-16
Identities = 44/103 (42%), Positives = 66/103 (64%), Gaps = 1/103 (0%)
Frame = +1
Query: 97 NELKCPILGLGTWK-SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 273
N ++ P++GLGT+K + EV QA+ A+ GYRHID A +YGNE+ +G+AI K+
Sbjct: 12 NGVEIPLIGLGTYKMTDEHEVYQAIITALQNGYRHIDTAQIYGNEELIGKAI----KDSG 67
Query: 274 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLI 402
V R+++F+TSK+WN H+ D + L L+ YLDL L+
Sbjct: 68 VPRKEIFLTSKIWNANHKYDAALQEIDNILKRLDTDYLDLCLV 110
>UniRef50_Q18483 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 287
Score = 88.2 bits (209), Expect = 1e-16
Identities = 43/101 (42%), Positives = 63/101 (62%), Gaps = 1/101 (0%)
Frame = +1
Query: 112 PILGLGTWKSKPGEVTQAVKDA-IDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 288
P++G+GTW+ + E+ + V DA GYR ID A VY NE ++G + + + RED
Sbjct: 12 PLIGIGTWQVQKEEILRQVIDAGFKEGYRFIDTAQVYNNEAKIGRILEKLLPANGLKRED 71
Query: 289 LFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 411
++ITSKL + R +++E+L NL V+YLDL LIHWP
Sbjct: 72 IWITSKLAPSNAGVKKARESIEESLSNLKVEYLDLLLIHWP 112
>UniRef50_Q5B034 Cluster: Putative uncharacterized protein; n=1;
Emericella nidulans|Rep: Putative uncharacterized
protein - Emericella nidulans (Aspergillus nidulans)
Length = 186
Score = 88.2 bits (209), Expect = 1e-16
Identities = 62/158 (39%), Positives = 80/158 (50%), Gaps = 1/158 (0%)
Frame = +1
Query: 67 MSSVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEA 246
MS + N P +GLGTWKS+PGEV +A+ A+ GYRHID A +G
Sbjct: 1 MSPPAHFKLNPGALIPAVGLGTWKSEPGEVARALAHALKTGYRHIDAA--------LG-- 50
Query: 247 ITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKE 426
V RE++FITSKLWNT H+P++ G LQ+TLD L V LDL Y E
Sbjct: 51 ---------VPREEIFITSKLWNT-HQPNIKEG-LQKTLDALGVDCLDL--------YNE 91
Query: 427 DGSLFPTDQSG-KIQFSDVDYVDTWKAMEPLVKEGSGQ 537
L P + G + D +TW+ ME K G +
Sbjct: 92 TSDLLPVNPDGTRAVDRSWDQSETWRQMEDFYKSGKAK 129
>UniRef50_Q2U219 Cluster: Aldo/keto reductase family proteins; n=6;
Pezizomycotina|Rep: Aldo/keto reductase family proteins
- Aspergillus oryzae
Length = 294
Score = 88.2 bits (209), Expect = 1e-16
Identities = 53/131 (40%), Positives = 75/131 (57%), Gaps = 9/131 (6%)
Frame = +1
Query: 73 SVPFVEFNNELKCPILGLGT---WKSKPG------EVTQAVKDAIDIGYRHIDCAYVYGN 225
+ P V+ N+ + PILG GT W + G E+ +A+K AI +GYRH+D A VYG
Sbjct: 8 NTPRVKLNDNVSIPILGYGTGTAWYKQAGDDSVNRELVEAIKTAIRLGYRHLDGAEVYGT 67
Query: 226 EKEVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIH 405
E E+G A IKE + RE+LF+T+K+ + A+ ++L L + Y+DLYLIH
Sbjct: 68 EAELGVA----IKESGIPREELFVTTKVITNIAD---IPSAIDQSLRKLQLNYVDLYLIH 120
Query: 406 WPQAYKEDGSL 438
P K DG L
Sbjct: 121 SPFFAKSDGEL 131
>UniRef50_Q5TNP1 Cluster: ENSANGP00000029046; n=2; Culicidae|Rep:
ENSANGP00000029046 - Anopheles gambiae str. PEST
Length = 331
Score = 87.8 bits (208), Expect = 1e-16
Identities = 53/150 (35%), Positives = 80/150 (53%), Gaps = 3/150 (2%)
Frame = +1
Query: 88 EFNNELKCPILGLGTWKSKPGEVTQAVKD-AIDIGYRHIDCAYVYGNEKEVGEAITSKIK 264
+ N P+ G GT++ E+ V D A++ GYRHID A VY NE+ +G A+ + +
Sbjct: 35 KLNTGFDIPLAGFGTYQIHGQELIYQVLDYALEAGYRHIDTAVVYRNEEYIGTALKTLLP 94
Query: 265 EGVVTREDLFITSKLWNTFHRPD-LVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLF 441
+ + RED+FITSKL + + + V ++++L NL YLDLYLIHWP + G
Sbjct: 95 KYNLKREDIFITSKLISQSGKDEAFVEQMVRKSLANLQTDYLDLYLIHWPGVSGKCGRWK 154
Query: 442 PTDQSGKIQFSDVDY-VDTWKAMEPLVKEG 528
+V Y +W A+ L +EG
Sbjct: 155 WLFGMQVTHPDNVKYRAASWNALSKLEREG 184
>UniRef50_Q24C22 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=4; Oligohymenophorea|Rep: Oxidoreductase,
aldo/keto reductase family protein - Tetrahymena
thermophila SB210
Length = 297
Score = 87.8 bits (208), Expect = 1e-16
Identities = 55/152 (36%), Positives = 83/152 (54%), Gaps = 1/152 (0%)
Frame = +1
Query: 76 VPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITS 255
VP + F P +G GT++ + + V +A+ IGY HID A VY NE+++ + I +
Sbjct: 13 VPILNFREGGSIPQIGYGTYELRQNDCIIGVTEALKIGYTHIDTASVYRNEQDIAKVIHN 72
Query: 256 KIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGS 435
+ REDLFITSK+ + + A+Q+ L LN++YLD LIHWP K
Sbjct: 73 PAYG--IKREDLFITSKISPGEQGYEQAKKAVQDMLTRLNIKYLDCVLIHWPGVSK---- 126
Query: 436 LFPTD-QSGKIQFSDVDYVDTWKAMEPLVKEG 528
L P D ++ +I+ ++TWKA+ L K G
Sbjct: 127 LPPNDPKNAQIR------LETWKALIELRKAG 152
>UniRef50_P47137 Cluster: Probable oxidoreductase YJR096W; n=8;
Saccharomycetales|Rep: Probable oxidoreductase YJR096W -
Saccharomyces cerevisiae (Baker's yeast)
Length = 282
Score = 87.4 bits (207), Expect = 2e-16
Identities = 43/113 (38%), Positives = 68/113 (60%), Gaps = 3/113 (2%)
Frame = +1
Query: 82 FVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 261
F + +N K P + LGT+ + + V + + GYRH D A +YGNEKEVG+ I +
Sbjct: 5 FYKLSNGFKIPSIALGTYDIPRSQTAEIVYEGVKCGYRHFDTAVLYGNEKEVGDGIIKWL 64
Query: 262 KE--GVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLN-VQYLDLYLIHWP 411
E G RE++F T+KLWN+ + + A+++ L+ ++ +QY+DL LIH P
Sbjct: 65 NEDPGNHKREEIFYTTKLWNSQNGYKRAKAAIRQCLNEVSGLQYIDLLLIHSP 117
>UniRef50_A5PDA8 Cluster: Putative oxidoreductase protein; n=1;
Erythrobacter sp. SD-21|Rep: Putative oxidoreductase
protein - Erythrobacter sp. SD-21
Length = 272
Score = 87.0 bits (206), Expect = 2e-16
Identities = 45/120 (37%), Positives = 67/120 (55%)
Frame = +1
Query: 67 MSSVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEA 246
M+ P + N+ + P LG GTW+ + + QAV AID+GY ID A +YGNEK VG
Sbjct: 1 MTDYPTLNLNDGRQIPQLGFGTWQMEEEDAPQAVSTAIDVGYWLIDTAAIYGNEKGVG-- 58
Query: 247 ITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKE 426
+GV D+F+ +K+WN D A ++ L+ L +++D+ LIHWP K+
Sbjct: 59 ------KGVGEWSDIFLQTKIWNDSQGYDRTLRAAEKCLERLGREHVDMLLIHWPCPEKD 112
>UniRef50_A7P424 Cluster: Chromosome chr1 scaffold_5, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr1 scaffold_5, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 247
Score = 87.0 bits (206), Expect = 2e-16
Identities = 53/132 (40%), Positives = 76/132 (57%), Gaps = 14/132 (10%)
Frame = +1
Query: 67 MSSVPFVEFNNELKC-PILGLGT--WKSKPGE-VTQAVKDAIDIGYRHIDCAYVYGNEKE 234
M S+P + + K P++G+ T + P E + ++ AI++GYRH DC Y +EK
Sbjct: 1 MISIPEMTLGSTGKAIPLVGMVTTVYPFAPSETMIDSILTAIELGYRHFDCVAAYLSEKP 60
Query: 235 VGEAITSKIKEGVV-TREDLFITSKLWNTFHRPDLVRGALQETL---------DNLNVQY 384
+GEAI +K G++ +R++LFITSKLW + D V ALQ TL NL + Y
Sbjct: 61 LGEAIKKAVKLGLIKSRDELFITSKLWCSDAHHDRVLPALQNTLKISSILSFSKNLQLDY 120
Query: 385 LDLYLIHWPQAY 420
LDLYLIHW +
Sbjct: 121 LDLYLIHWSDGH 132
>UniRef50_UPI00005A2CCB Cluster: PREDICTED: similar to Aldose
reductase (AR) (Aldehyde reductase); n=1; Canis lupus
familiaris|Rep: PREDICTED: similar to Aldose reductase
(AR) (Aldehyde reductase) - Canis familiaris
Length = 182
Score = 86.6 bits (205), Expect = 3e-16
Identities = 40/76 (52%), Positives = 53/76 (69%)
Frame = +1
Query: 97 NELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVV 276
N +K PI+GL TWKS P +VT+AVK +D+GY HIDC + N++EVG A+ K+K V
Sbjct: 27 NGIKVPIMGLATWKSPPSKVTEAVKVVMDLGYCHIDCTHKLQNKREVGLAVQEKLKGQGV 86
Query: 277 TREDLFITSKLWNTFH 324
REDL I S+L +T H
Sbjct: 87 KREDLSILSELQHTHH 102
>UniRef50_Q28P63 Cluster: Aldo/keto reductase; n=4;
Rhodobacteraceae|Rep: Aldo/keto reductase - Jannaschia
sp. (strain CCS1)
Length = 276
Score = 86.6 bits (205), Expect = 3e-16
Identities = 40/115 (34%), Positives = 68/115 (59%)
Frame = +1
Query: 67 MSSVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEA 246
M+ P ++F++ + P +G G W+ + V+ AI+IGYR ID AY+Y NE +GE
Sbjct: 1 MTDRPVIKFHDGAQIPQVGFGIWQVPQDIAGETVRSAIEIGYRMIDGAYLYMNEAGLGEG 60
Query: 247 ITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 411
++ + R+++F+T+K+WN R +++ +L + V+ LDL LIHWP
Sbjct: 61 ----LRASGLPRDEVFVTTKVWNNEQGAAKARASVERSLKTIGVEQLDLVLIHWP 111
>UniRef50_Q3E9M9 Cluster: Uncharacterized protein At5g01670.2; n=7;
Magnoliophyta|Rep: Uncharacterized protein At5g01670.2 -
Arabidopsis thaliana (Mouse-ear cress)
Length = 349
Score = 86.6 bits (205), Expect = 3e-16
Identities = 62/167 (37%), Positives = 83/167 (49%), Gaps = 27/167 (16%)
Frame = +1
Query: 106 KCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRE 285
K P +GLGTW+S V ++ GYRHID A+ YG+++EVG+ I + G+ R
Sbjct: 23 KIPAVGLGTWRSGSQAAHAVVTAIVEGGYRHIDTAWEYGDQREVGQGIKRAMHAGL-ERR 81
Query: 286 DLFIT----------------SKLWN-----------TFHRPDLVRGALQETLDNLNVQY 384
DLF+T S L N T P+ VR ALQ TL L ++Y
Sbjct: 82 DLFVTSKLWYTLILRKMINLSSPLMNVLVGTCLNKRCTELSPERVRPALQNTLKELQLEY 141
Query: 385 LDLYLIHWPQAYKEDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKE 525
LDLYLIHWP +E S P ++G + D D W+ ME L K+
Sbjct: 142 LDLYLIHWPIRLREGASKPP--KAGDV--LDFDMEGVWREMENLSKD 184
>UniRef50_A2QB88 Cluster: Contig An01c0460, complete genome.
precursor; n=1; Aspergillus niger|Rep: Contig An01c0460,
complete genome. precursor - Aspergillus niger
Length = 351
Score = 86.6 bits (205), Expect = 3e-16
Identities = 61/156 (39%), Positives = 83/156 (53%), Gaps = 12/156 (7%)
Frame = +1
Query: 97 NELKCPILGLGTWKSKPGE--VTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEG 270
+E+ P +GLGT++ G V +AV A+ GYRHID A YGNE EVGEA IKE
Sbjct: 42 SEMTFPAVGLGTFQGDAGNRGVKEAVLQALRCGYRHIDTATAYGNEIEVGEA----IKES 97
Query: 271 VVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQY-LDLYL-----IHWPQAYK--E 426
+ RE++ +T+KL T+HR V AL +L+ L + Y L ++L P AY
Sbjct: 98 RIPREEIIVTTKLAQTWHRVSDVERALDLSLERLQLNYGLSMHLYSASSYSVPHAYSPGP 157
Query: 427 DGSLFPTDQSGKIQFSDV--DYVDTWKAMEPLVKEG 528
D + I ++ DY TW AME LV +G
Sbjct: 158 DNNTIRHPNGKPIIDHELSRDYPSTWAAMESLVDKG 193
>UniRef50_Q1Q8W8 Cluster: Aldo/keto reductase; n=1; Psychrobacter
cryohalolentis K5|Rep: Aldo/keto reductase -
Psychrobacter cryohalolentis (strain K5)
Length = 282
Score = 86.2 bits (204), Expect = 4e-16
Identities = 41/102 (40%), Positives = 62/102 (60%), Gaps = 2/102 (1%)
Frame = +1
Query: 112 PILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 291
P+LGLGTW+S + V + +GY HID A YGNE EVG+ IK+ V R+
Sbjct: 17 PVLGLGTWQSTGQDCIDVVSQGLRMGYEHIDTAQAYGNEVEVGKG----IKQSGVARDKF 72
Query: 292 FITSKLW--NTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 411
F+T+K++ + P+ + A + +L+NL+ Y+DL L+HWP
Sbjct: 73 FLTTKIFPDDMKFEPEKLVAAAKRSLENLDTDYVDLLLLHWP 114
>UniRef50_Q927P9 Cluster: Lin2739 protein; n=12; Bacteria|Rep:
Lin2739 protein - Listeria innocua
Length = 283
Score = 85.8 bits (203), Expect = 6e-16
Identities = 48/110 (43%), Positives = 65/110 (59%), Gaps = 1/110 (0%)
Frame = +1
Query: 85 VEFNNELKCPILGLGTWK-SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 261
V+ NN ++ PILG GT++ + GE QAVK+AI GYRHID A Y NE+ VG I +
Sbjct: 4 VKLNNGIEVPILGFGTYQITDAGEAEQAVKEAIAAGYRHIDTAQSYMNEEAVGRGIAA-- 61
Query: 262 KEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 411
V R++LFIT+K+W V + +L L + Y+DL LIH P
Sbjct: 62 --SGVDRKELFITTKIWVENVSYKGVMSSFDRSLKRLGLDYIDLLLIHQP 109
>UniRef50_Q11BF8 Cluster: Aldo/keto reductase; n=12; Bacteria|Rep:
Aldo/keto reductase - Mesorhizobium sp. (strain BNC1)
Length = 308
Score = 85.8 bits (203), Expect = 6e-16
Identities = 40/103 (38%), Positives = 65/103 (63%)
Frame = +1
Query: 103 LKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTR 282
++ P++GLG +++ P E T AV++A+ +GYRHID A YGNE+EVGE I+ + R
Sbjct: 27 VEMPMIGLGVFQTPPDETTAAVEEALRLGYRHIDTAAAYGNEREVGEG----IRRAGIAR 82
Query: 283 EDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 411
+++FI +K+W + + D A ++ L V +DL L+H P
Sbjct: 83 DEVFIETKIWISDYGYDETLHAFDKSAGKLGVDQIDLLLLHQP 125
>UniRef50_Q043M4 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=2; Lactobacillus|Rep: Aldo/keto
reductase of diketogulonate reductase family -
Lactobacillus gasseri (strain ATCC 33323 / DSM 20243)
Length = 273
Score = 85.8 bits (203), Expect = 6e-16
Identities = 44/112 (39%), Positives = 64/112 (57%)
Frame = +1
Query: 94 NNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 273
NN++K PI G GT++ P + QAV A + GYR ID A Y NE++VGEA +K
Sbjct: 7 NNDVKIPIFGFGTYEISPDQTKQAVLSAFEEGYRLIDTAQYYQNEQQVGEA----VKASG 62
Query: 274 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKED 429
+ R+++FIT+K + + L E+L + + Y DL LIHWP + D
Sbjct: 63 LNRDEVFITTKTMTDGYEDTKI--GLDESLRRIGLDYFDLVLIHWPMGHDID 112
>UniRef50_Q8ZH36 Cluster: 2,5-diketo-D-gluconic acid reductase B;
n=91; Proteobacteria|Rep: 2,5-diketo-D-gluconic acid
reductase B - Yersinia pestis
Length = 267
Score = 85.4 bits (202), Expect = 7e-16
Identities = 42/108 (38%), Positives = 64/108 (59%)
Frame = +1
Query: 103 LKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTR 282
+ P+ GLGT++ + V +V A+ +GYR ID A +Y NE VG+AI +E + R
Sbjct: 1 MSIPVFGLGTFRLQDQIVIDSVSQALTLGYRAIDTAQIYENEAPVGQAI----QESGINR 56
Query: 283 EDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKE 426
++LFIT+K+W D + +L+E++ L Y+DL LIHWP E
Sbjct: 57 DELFITTKIWIANLSKDKLIPSLRESIQKLKTDYVDLTLIHWPSPNDE 104
>UniRef50_Q7VHE1 Cluster: Putative uncharacterized protein; n=1;
Helicobacter hepaticus|Rep: Putative uncharacterized
protein - Helicobacter hepaticus
Length = 270
Score = 85.0 bits (201), Expect = 1e-15
Identities = 45/121 (37%), Positives = 73/121 (60%)
Frame = +1
Query: 94 NNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 273
NN +K PILGLGT+ +A+ +AI++GYR D A +Y NE E+G AI + +K G
Sbjct: 7 NNGVKMPILGLGTYSLTGKAGQKAMSEAIEVGYRLFDSAQMYNNEAELGAAINAAVKGG- 65
Query: 274 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQ 453
+ RE+ FI +KL + DL + +++++L L + Y+D LIH P Y + +++ +
Sbjct: 66 IKREEFFIQTKLLES-SSEDLAKKSIEKSLKTLGLDYIDSLLIHMP--YSQSKAMYRAME 122
Query: 454 S 456
S
Sbjct: 123 S 123
>UniRef50_A5VK30 Cluster: 2,5-didehydrogluconate reductase; n=2;
Lactobacillus reuteri|Rep: 2,5-didehydrogluconate
reductase - Lactobacillus reuteri F275
Length = 300
Score = 85.0 bits (201), Expect = 1e-15
Identities = 46/112 (41%), Positives = 61/112 (54%), Gaps = 1/112 (0%)
Frame = +1
Query: 79 PFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSK 258
P ++ NN P LGLG WK+ E Q VK+AI Y ID A YGNE VG+ I
Sbjct: 11 PKIKLNNGHLIPQLGLGVWKASLAETQQMVKEAIMNDYVLIDTAKQYGNEAAVGQGIQDG 70
Query: 259 IKEGVVTREDLFITSKLWNTFHRP-DLVRGALQETLDNLNVQYLDLYLIHWP 411
K R+ +F+T+K++N D +R A+ E L L Y+DL L+HWP
Sbjct: 71 FKATGRKRDSIFLTTKIFNGDQGDYDKLRQAVNEQLKKLQTNYVDLLLLHWP 122
>UniRef50_A3C1Z7 Cluster: Putative uncharacterized protein; n=2;
Oryza sativa (japonica cultivar-group)|Rep: Putative
uncharacterized protein - Oryza sativa subsp. japonica
(Rice)
Length = 288
Score = 84.6 bits (200), Expect = 1e-15
Identities = 51/147 (34%), Positives = 77/147 (52%), Gaps = 8/147 (5%)
Frame = +1
Query: 112 PILGLGTWK-----SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVV 276
P +G+GT + P V V AI+ GYRH D A VY E +G+A+ ++ G+V
Sbjct: 13 PRVGMGTASFPLGATDPSTVKDVVLRAIEAGYRHFDTAAVYQTEAILGDAVAEAVRAGLV 72
Query: 277 -TREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYK--EDGSLFPT 447
+R++L+ITSKLW P V +L+ L + ++YLDLYLIH+P + + ED
Sbjct: 73 ASRDELYITSKLWVAHAHPGHVLPSLRRALRKMQMEYLDLYLIHFPVSMRLAEDPESMTY 132
Query: 448 DQSGKIQFSDVDYVDTWKAMEPLVKEG 528
+ + +D WK ME + G
Sbjct: 133 SKDDLVM---MDMEGVWKEMEECQRLG 156
>UniRef50_Q54NR2 Cluster: Aldo-keto reductase; n=3; Dictyostelium
discoideum AX4|Rep: Aldo-keto reductase - Dictyostelium
discoideum AX4
Length = 305
Score = 84.2 bits (199), Expect = 2e-15
Identities = 52/149 (34%), Positives = 78/149 (52%), Gaps = 6/149 (4%)
Frame = +1
Query: 97 NELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI--KEG 270
N +K P+LG+GT+K ++ +K ++ GYR ID A +Y NE+ +G+ + + +G
Sbjct: 23 NPIKMPMLGIGTFKLN--DIENIIKVGLENGYRRIDTASMYNNEERIGKVLNEMVTKNDG 80
Query: 271 V----VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSL 438
+ + REDLFITSK + A + +L L + YLD YLIHWP DGS
Sbjct: 81 LDGKKIKREDLFITSKCSFMEQGYENALKAFESSLKKLQLDYLDCYLIHWPGVKGLDGS- 139
Query: 439 FPTDQSGKIQFSDVDYVDTWKAMEPLVKE 525
D IQ TW+A+E L ++
Sbjct: 140 ---DSGNSIQ-----RAQTWRALEKLYQD 160
>UniRef50_Q17568 Cluster: Putative uncharacterized protein; n=1;
Caenorhabditis elegans|Rep: Putative uncharacterized
protein - Caenorhabditis elegans
Length = 287
Score = 84.2 bits (199), Expect = 2e-15
Identities = 48/149 (32%), Positives = 86/149 (57%), Gaps = 2/149 (1%)
Frame = +1
Query: 88 EFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKE 267
+ N + P L LGT+++K ++ AV +A+ +GYR D A Y NEK++G A+ + +
Sbjct: 3 KLKNGQEIPKLALGTYEAKGDQLFAAVDEALKVGYRSFDTAKYYENEKDLGLALKTLLPR 62
Query: 268 GVVTREDLFITSKL--WNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLF 441
+ ED+++TSK+ +++ + +L+R + E+L+ L+ +YLDL L+H+P+
Sbjct: 63 HNICSEDIYLTSKVFPYSSKNAAELIRKDVNESLELLDRKYLDLVLVHYPR--------- 113
Query: 442 PTDQSGKIQFSDVDYVDTWKAMEPLVKEG 528
P D + + + DTW A+E L EG
Sbjct: 114 PLDTEDLNENNKMYRKDTWIALEKLHAEG 142
>UniRef50_O13848 Cluster: NADH/NADPH dependent indole-3-acetaldehyde
reductase AKR3C2; n=1; Schizosaccharomyces pombe|Rep:
NADH/NADPH dependent indole-3-acetaldehyde reductase
AKR3C2 - Schizosaccharomyces pombe (Fission yeast)
Length = 284
Score = 84.2 bits (199), Expect = 2e-15
Identities = 51/115 (44%), Positives = 69/115 (60%), Gaps = 6/115 (5%)
Frame = +1
Query: 100 ELKCPILGLGT--WKSKPGEVTQ----AVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 261
++ P G+GT +K + GE+ + +VK+A+ G+ HIDCA VYGNE+EVG A +
Sbjct: 9 KIPVPAYGVGTALFKKEKGEINRTIVDSVKNALAAGFIHIDCAEVYGNEEEVGVA----L 64
Query: 262 KEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKE 426
KE V R LFITSK+ H D + AL E+L L YLDLYL+H P + E
Sbjct: 65 KEANVPRSKLFITSKV---MHNVDNIPEALNESLRKLGTDYLDLYLLHSPIPFYE 116
>UniRef50_Q890A0 Cluster: Oxidoreductase; n=6; Lactobacillales|Rep:
Oxidoreductase - Lactobacillus plantarum
Length = 282
Score = 83.8 bits (198), Expect = 2e-15
Identities = 52/145 (35%), Positives = 75/145 (51%), Gaps = 1/145 (0%)
Frame = +1
Query: 97 NELKCPILGLGTWKSKPGEVT-QAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 273
N + P + GTW+ GE T QAV+ A+ GYRHID A Y NE VG+A I++
Sbjct: 12 NGVNIPKVAFGTWQIPGGEATYQAVRAALAAGYRHIDTALAYQNEASVGQA----IRDSG 67
Query: 274 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQ 453
+ RE +F+T+KL +L NL + Y+DLYL+H P +P Q
Sbjct: 68 IPREQIFVTTKLPAETKSYQGALNDFDRSLKNLGLDYVDLYLVHAP---------WPWGQ 118
Query: 454 SGKIQFSDVDYVDTWKAMEPLVKEG 528
G++ D +D W+AME + + G
Sbjct: 119 VGRVY--DEANLDVWQAMEAIYQSG 141
>UniRef50_Q5FT75 Cluster: Putative 2,5-diketo-D-gluconic acid
reductase; n=1; Gluconobacter oxydans|Rep: Putative
2,5-diketo-D-gluconic acid reductase - Gluconobacter
oxydans (Gluconobacter suboxydans)
Length = 279
Score = 83.8 bits (198), Expect = 2e-15
Identities = 50/148 (33%), Positives = 74/148 (50%)
Frame = +1
Query: 85 VEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 264
+ F++ P +GLG W++ P E + VK+A+ +GYR +D A +Y NE+ VG
Sbjct: 14 ISFHDGHTMPQIGLGVWETPPDETAEVVKEAVKLGYRSVDTARLYKNEEGVG-------- 65
Query: 265 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 444
+G+ ++F+T+KLWN D A +E+ L LDLYLIHWP
Sbjct: 66 KGLEDHPEIFLTTKLWNDEQGYDSTLRAYEESARLLRRPVLDLYLIHWPMP--------- 116
Query: 445 TDQSGKIQFSDVDYVDTWKAMEPLVKEG 528
+ YV+TWKA+ L K G
Sbjct: 117 ---------AQGQYVETWKALVELKKSG 135
>UniRef50_Q5FKI1 Cluster: Reductase-dehydrogenase; n=1;
Lactobacillus acidophilus|Rep: Reductase-dehydrogenase -
Lactobacillus acidophilus
Length = 271
Score = 83.8 bits (198), Expect = 2e-15
Identities = 52/148 (35%), Positives = 76/148 (51%)
Frame = +1
Query: 85 VEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 264
V NN K P + LGTW EV + V+ A++IGYR D A YGNE VG+ I +
Sbjct: 7 VILNNGEKIPQIQLGTWLINNDEVNKVVRQAVNIGYRGFDTAKDYGNESGVGKGIWN--- 63
Query: 265 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 444
+ R D+F+T+KL + + A+ LD ++Y+DL LIH PQ + E
Sbjct: 64 -SDIERSDIFLTTKLPTAVKDYEGTKKAIDAALDKFGLEYIDLLLIHSPQPWIE------ 116
Query: 445 TDQSGKIQFSDVDYVDTWKAMEPLVKEG 528
+++ F ++ W+AME VK G
Sbjct: 117 VNRTNDRHFK--GNLENWRAMEEAVKAG 142
>UniRef50_Q572D2 Cluster: Aldo-keto reductase, putative; n=1;
Phytophthora infestans|Rep: Aldo-keto reductase,
putative - Phytophthora infestans (Potato late blight
fungus)
Length = 255
Score = 83.4 bits (197), Expect = 3e-15
Identities = 43/119 (36%), Positives = 72/119 (60%), Gaps = 1/119 (0%)
Frame = +1
Query: 73 SVPFVEFNNELKCPILGLGTWKSKPG-EVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAI 249
+VP + + P++GLG ++S+PG E A+ ++ +GYRHID A +YGNE++VG A
Sbjct: 4 NVPTKILPSGARIPMIGLGVYQSEPGPETYNAILTSLKLGYRHIDTAEIYGNEEDVGRA- 62
Query: 250 TSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKE 426
+++ + RE++F+T+KL+ T A + + D L + Y+ LYL+H P KE
Sbjct: 63 ---VRDSGIPREEIFVTTKLFTTNWGYSKALAAGKASNDRLGIVYIYLYLLHAPGPPKE 118
>UniRef50_UPI000155CAC7 Cluster: PREDICTED: hypothetical protein;
n=1; Ornithorhynchus anatinus|Rep: PREDICTED:
hypothetical protein - Ornithorhynchus anatinus
Length = 419
Score = 83.0 bits (196), Expect = 4e-15
Identities = 60/148 (40%), Positives = 80/148 (54%), Gaps = 1/148 (0%)
Frame = +1
Query: 76 VPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAI-DIGYRHIDCAYVYGNEKEVGEAIT 252
VP V N L PILGLGT G AV A+ + G RHID A YG E +G+AI
Sbjct: 12 VPTVPLANGLNIPILGLGT-SHVGGYSHDAVIYALKECGIRHIDTAKRYGCELLLGKAI- 69
Query: 253 SKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDG 432
+E V RE+L+IT+KLW T + + + + E+ + L V+YLDL+LIHWP A
Sbjct: 70 ---QESGVKREELWITTKLWLTDYGYESAKQSCLESCNRLGVEYLDLFLIHWPDAQ---- 122
Query: 433 SLFPTDQSGKIQFSDVDYVDTWKAMEPL 516
P S + + +TW+AME L
Sbjct: 123 --LPGKSSREAR------AETWRAMEEL 142
>UniRef50_Q9X265 Cluster: Oxidoreductase, aldo/keto reductase
family; n=2; Thermotoga|Rep: Oxidoreductase, aldo/keto
reductase family - Thermotoga maritima
Length = 274
Score = 83.0 bits (196), Expect = 4e-15
Identities = 49/109 (44%), Positives = 61/109 (55%), Gaps = 9/109 (8%)
Frame = +1
Query: 112 PILGLGTWK---------SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 264
P LGLGTW S+ E+ + +K AI +GY HID A YG E I IK
Sbjct: 14 PALGLGTWGIGGFETPDYSRDEEMVELLKTAIKMGYTHIDTAEYYGGG-HTEELIGKAIK 72
Query: 265 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 411
+ REDLFI SK+W T R D + +L+ TL L+ Y+DLYLIHWP
Sbjct: 73 D--FRREDLFIVSKVWPTHLRRDDLLRSLENTLKRLDTDYVDLYLIHWP 119
>UniRef50_A1UEC5 Cluster: 2,5-didehydrogluconate reductase; n=20;
Corynebacterineae|Rep: 2,5-didehydrogluconate reductase
- Mycobacterium sp. (strain KMS)
Length = 283
Score = 83.0 bits (196), Expect = 4e-15
Identities = 42/114 (36%), Positives = 65/114 (57%)
Frame = +1
Query: 70 SSVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAI 249
+ +P V N+ P+LGLG + E ++V A++ GYR ID A VYGNE VG A+
Sbjct: 9 AGIPSVSLNDGHSIPVLGLGVGELSEAEAERSVAAALEAGYRLIDTAAVYGNEAAVGRAV 68
Query: 250 TSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 411
+ + RE++++T+KL + A + +L+ L + Y+DLYLIHWP
Sbjct: 69 NA----SGIPREEIYVTTKLAVADQGFGTSQDAARASLERLGLDYVDLYLIHWP 118
>UniRef50_A0L1A2 Cluster: Aldo/keto reductase; n=8;
Gammaproteobacteria|Rep: Aldo/keto reductase -
Shewanella sp. (strain ANA-3)
Length = 280
Score = 83.0 bits (196), Expect = 4e-15
Identities = 42/100 (42%), Positives = 61/100 (61%)
Frame = +1
Query: 112 PILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 291
P+LG GT++ K AV A++ G RHID A +YGNE+ VG+AI + + RE+L
Sbjct: 18 PMLGTGTFRLKDNAAFDAVLMALEEGSRHIDTAQIYGNEQAVGDAINT----SGIPREEL 73
Query: 292 FITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 411
FIT+K+W + ++ ++L L +YLDL LIHWP
Sbjct: 74 FITTKVWTENLTKERFETSVIDSLTALQTKYLDLLLIHWP 113
>UniRef50_Q8Y463 Cluster: Lmo2592 protein; n=40; Bacteria|Rep:
Lmo2592 protein - Listeria monocytogenes
Length = 283
Score = 82.6 bits (195), Expect = 5e-15
Identities = 47/110 (42%), Positives = 63/110 (57%), Gaps = 1/110 (0%)
Frame = +1
Query: 85 VEFNNELKCPILGLGTWK-SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 261
V+ NN ++ PILG GT++ + E AVKDAI GYRHID A Y NE+ VG I +
Sbjct: 4 VKLNNGVEVPILGFGTYQITDAAEAEHAVKDAIKAGYRHIDTAQSYMNEEAVGRGIAA-- 61
Query: 262 KEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 411
V R++LFIT+K+W V + +L L + Y+DL LIH P
Sbjct: 62 --SGVDRKELFITTKIWVENVSYKGVMSSFDRSLKRLGLDYVDLLLIHQP 109
>UniRef50_Q5V663 Cluster: Aldehyde reductase; n=6;
Halobacteriaceae|Rep: Aldehyde reductase - Haloarcula
marismortui (Halobacterium marismortui)
Length = 279
Score = 82.6 bits (195), Expect = 5e-15
Identities = 42/112 (37%), Positives = 63/112 (56%), Gaps = 1/112 (0%)
Frame = +1
Query: 112 PILGLGTWKSKPGE-VTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 288
P+LGLGTW+++ E ++V+ A++ GYRHID A Y NE VG+ I + V R+D
Sbjct: 18 PMLGLGTWQNEDAEQCAESVRTALEAGYRHIDTAQAYDNESAVGDGIAA----ADVDRDD 73
Query: 289 LFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFP 444
+F+ +K+W + D V +E+LD L V +DL +HW E P
Sbjct: 74 IFLATKVWISNLSHDDVIETTEESLDKLGVDSVDLLYVHWAAGEYEPEETLP 125
>UniRef50_Q235V6 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=2; Tetrahymena thermophila SB210|Rep:
Oxidoreductase, aldo/keto reductase family protein -
Tetrahymena thermophila SB210
Length = 332
Score = 81.8 bits (193), Expect = 9e-15
Identities = 42/119 (35%), Positives = 73/119 (61%), Gaps = 1/119 (0%)
Frame = +1
Query: 88 EFNNELKCPILGLGTWK-SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 264
+ NN P++GLGT+ + E+T ++ A+D GYRHID A Y NE +GE++ + K
Sbjct: 9 KLNNGQIMPLVGLGTYLLNSKEEMTNLLRTALDAGYRHIDTAVNYQNEAMIGESLKTIFK 68
Query: 265 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLF 441
EG +R+DLFI SK++ ++ + +++++L L + Y+DLY +H+P + + F
Sbjct: 69 EGKYSRKDLFIVSKVFP--NKGINMLESVKKSLKELQLDYVDLYYLHFPLGFLSEKEEF 125
>UniRef50_P91997 Cluster: Putative uncharacterized protein; n=4;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 297
Score = 81.8 bits (193), Expect = 9e-15
Identities = 40/115 (34%), Positives = 67/115 (58%), Gaps = 1/115 (0%)
Frame = +1
Query: 88 EFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKE 267
+ N+ P +G GT+K V A+ A+ GYR D A Y NEKE+GEA+ + +
Sbjct: 14 KLNSGYNIPFVGFGTYKVTGENVPPAIDAALTAGYRMFDTAKYYLNEKELGEALKILLPK 73
Query: 268 GVVTREDLFITSKLW-NTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKED 429
++R D+F+TSK + + + + RG ++E+L +L Y+D+YL+H+P+ D
Sbjct: 74 HGLSRSDVFLTSKFFPESKNCREACRGFVEESLQSLQTDYIDMYLVHYPKPNDSD 128
>UniRef50_Q5KD52 Cluster: Oxidoreductase, putative; n=1;
Filobasidiella neoformans|Rep: Oxidoreductase, putative
- Cryptococcus neoformans (Filobasidiella neoformans)
Length = 321
Score = 81.8 bits (193), Expect = 9e-15
Identities = 54/124 (43%), Positives = 74/124 (59%), Gaps = 6/124 (4%)
Frame = +1
Query: 76 VPFVEF--NNELKCPILGLGTWKSKPGEVTQ-AVKDAIDIGYRHIDCAY---VYGNEKEV 237
+PF E N+ + P + GTWK P EVT V AID+G+ HID A VY NE+EV
Sbjct: 1 MPFGEITLNDGHRIPAIAFGTWKI-PKEVTPFQVGQAIDVGFDHIDTAQGRIVYHNEEEV 59
Query: 238 GEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQA 417
G+AI KE ++R L++T+K W+ R ++ E+L+ L ++YLDLYLIH PQ
Sbjct: 60 GQAI----KESGLSRNQLWVTTK-WSGIDGKG-ARQSIGESLEKLGLEYLDLYLIHSPQV 113
Query: 418 YKED 429
K D
Sbjct: 114 TKGD 117
>UniRef50_Q4WUF7 Cluster: Aldo-keto reductase, putative; n=3;
Pezizomycotina|Rep: Aldo-keto reductase, putative -
Aspergillus fumigatus (Sartorya fumigata)
Length = 283
Score = 81.8 bits (193), Expect = 9e-15
Identities = 41/106 (38%), Positives = 67/106 (63%), Gaps = 2/106 (1%)
Frame = +1
Query: 94 NNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 273
N+++K P LG G ++S G+ Q+ A++ GYRHID A YGNEKEVGEA +++
Sbjct: 15 NSDVKIPRLGFGVYRSPTGQCVQSSLRALEAGYRHIDTAQFYGNEKEVGEA----LRKCG 70
Query: 274 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQ--YLDLYLIH 405
+ R D+F+T+K+ + P+ L E+++ + + Y+DL+LIH
Sbjct: 71 IPRSDVFVTTKILSPAGSPEATYQKLLESVEKIGGRDGYVDLFLIH 116
>UniRef50_Q4WP69 Cluster: Aldehyde reductase, putative; n=1;
Aspergillus fumigatus|Rep: Aldehyde reductase, putative
- Aspergillus fumigatus (Sartorya fumigata)
Length = 350
Score = 81.8 bits (193), Expect = 9e-15
Identities = 52/121 (42%), Positives = 64/121 (52%), Gaps = 6/121 (4%)
Frame = +1
Query: 184 IGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETL 363
+GYRHID A V NE EVG K+ V RE +F+TSKLWNT H P V AL +T+
Sbjct: 72 VGYRHIDSAAVGLNEAEVGRGW----KKLGVPREGIFLTSKLWNTHHHPSHVEEALDKTV 127
Query: 364 DNLNVQYLDLYLI----HWPQAYKEDGSLFPTDQSGKIQFS--DVDYVDTWKAMEPLVKE 525
+L YLDLYL+ H Y+ P + G +F D+ DTW A E LV
Sbjct: 128 KDLQTNYLDLYLLYPLGHILHTYQRH---IPASRPGHKRFRLVDIPIGDTWAAREKLVNA 184
Query: 526 G 528
G
Sbjct: 185 G 185
>UniRef50_A6VNW9 Cluster: Aldo/keto reductase precursor; n=1;
Actinobacillus succinogenes 130Z|Rep: Aldo/keto
reductase precursor - Actinobacillus succinogenes 130Z
Length = 315
Score = 81.0 bits (191), Expect = 2e-14
Identities = 39/109 (35%), Positives = 67/109 (61%)
Frame = +1
Query: 85 VEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 264
V+ NN ++ PI+G+G W P + ++V +A+ GYR ID A +Y NE+ VG A ++
Sbjct: 45 VKLNNGIEMPIIGIGVWTLTPEQTEKSVGEALKAGYRLIDTARMYRNEQAVGRA----VR 100
Query: 265 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 411
+ + RE++FIT+K++ + + A+ E L L+ Y+DL L+H+P
Sbjct: 101 DSGIPREEIFITTKIYGSGDYAN-AEAAINERLRLLDTDYIDLLLLHYP 148
>UniRef50_UPI0000DB6EE9 Cluster: PREDICTED: similar to C35D10.6;
n=2; Endopterygota|Rep: PREDICTED: similar to C35D10.6 -
Apis mellifera
Length = 292
Score = 80.6 bits (190), Expect = 2e-14
Identities = 40/104 (38%), Positives = 67/104 (64%), Gaps = 2/104 (1%)
Frame = +1
Query: 112 PILGLGTWKSKPGE-VTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 288
P++G GT+K + E V Q V +++++G+R ID A Y NE+++G A+ + + + + R D
Sbjct: 17 PLIGFGTYKIQGRELVYQVVDESLNVGFRSIDTAVGYRNEEDIGYALKNLLPKYNLQRSD 76
Query: 289 LFITSKLWNTFH-RPDLVRGALQETLDNLNVQYLDLYLIHWPQA 417
+FIT+KL + + P + +Q++L N Y+DLYLIHWP A
Sbjct: 77 IFITTKLPPSVNGDPKGIEQCVQKSLKAFNTTYIDLYLIHWPGA 120
>UniRef50_A0AWM8 Cluster: Aldo/keto reductase; n=4;
Actinomycetales|Rep: Aldo/keto reductase - Arthrobacter
sp. (strain FB24)
Length = 287
Score = 80.2 bits (189), Expect = 3e-14
Identities = 53/153 (34%), Positives = 75/153 (49%)
Frame = +1
Query: 70 SSVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAI 249
S +P ++ + P LGLGTW E AV+ A+ GYR +D A+ Y NE+ VG
Sbjct: 11 SDIPRLKLPHGHTIPRLGLGTWPMLEDECETAVRFALQSGYRLVDTAFQYRNEEAVGRG- 69
Query: 250 TSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKED 429
I+ V R +LFI+SK H D V+ A E+L L + +LD+++ HW
Sbjct: 70 ---IRTAGVPRSELFISSKFNKESHSIDGVQRAYDESLRKLGLDHLDMFMCHW------- 119
Query: 430 GSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEG 528
P GK YVD WK + L++EG
Sbjct: 120 ----PVPALGK-------YVDAWKGLVKLLEEG 141
>UniRef50_Q5FK99 Cluster: Oxidoreductase aldo-keto reductase family;
n=5; Lactobacillus|Rep: Oxidoreductase aldo-keto
reductase family - Lactobacillus acidophilus
Length = 289
Score = 79.8 bits (188), Expect = 4e-14
Identities = 46/119 (38%), Positives = 67/119 (56%), Gaps = 1/119 (0%)
Frame = +1
Query: 67 MSSVPFVEFNNELKCPILGLGTWK-SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGE 243
M+ +P ++ N+ + P LG G ++ S E +AV+ AI GYR ID A Y N+ VGE
Sbjct: 1 MTDIPKIKLNDGNEIPQLGFGVFQISNHDEAVKAVESAISNGYRLIDTAEAYNNQTAVGE 60
Query: 244 AITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAY 420
AI K V R+D+F+T+KLW + + A+ E L L Y+D+ L+H QAY
Sbjct: 61 AI----KNSDVNRDDIFLTTKLWVSNFTYEKASKAIDEDLKELGTDYIDMMLLH--QAY 113
>UniRef50_Q1M4Z6 Cluster: Putative aldo-keto reductase/oxidase; n=1;
Rhizobium leguminosarum bv. viciae 3841|Rep: Putative
aldo-keto reductase/oxidase - Rhizobium leguminosarum
bv. viciae (strain 3841)
Length = 274
Score = 79.8 bits (188), Expect = 4e-14
Identities = 40/105 (38%), Positives = 60/105 (57%)
Frame = +1
Query: 112 PILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 291
P +G GTW E Q V A++ G RHID A YGNE++V I K+ V R ++
Sbjct: 11 PQMGYGTWNRSADEAHQGVIWALEAGCRHIDTAQGYGNEQDVARGI----KDAGVARNEI 66
Query: 292 FITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKE 426
FIT+K+ + P V +++E+L+ L V +DL L+HWP + +
Sbjct: 67 FITTKVKPDNYGPGAVMPSVRESLEKLRVDQVDLLLLHWPSPHNK 111
>UniRef50_Q5UYI9 Cluster: Oxidoreductase; n=1; Haloarcula
marismortui|Rep: Oxidoreductase - Haloarcula marismortui
(Halobacterium marismortui)
Length = 264
Score = 79.8 bits (188), Expect = 4e-14
Identities = 39/99 (39%), Positives = 58/99 (58%)
Frame = +1
Query: 115 ILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDLF 294
++G+GTW V ++V+ +++GY H+D A Y NE E+GEA+ RED+F
Sbjct: 1 MVGVGTWDIDGDTVQKSVRAGLNVGYAHVDTAEGYKNESEIGEALAD------YDREDVF 54
Query: 295 ITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 411
+TSK+ + V A + +LD L YLDLYL+HWP
Sbjct: 55 LTSKVLPKHLDYESVIEACEASLDRLGTDYLDLYLVHWP 93
>UniRef50_Q8EVS8 Cluster: Oxidoreductase; n=1; Mycoplasma
penetrans|Rep: Oxidoreductase - Mycoplasma penetrans
Length = 289
Score = 79.4 bits (187), Expect = 5e-14
Identities = 46/117 (39%), Positives = 65/117 (55%)
Frame = +1
Query: 61 VKMSSVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVG 240
+K S+V + NN K P +G G ++ E VK AI IGYR ID A Y NEKE G
Sbjct: 1 MKTSNVKLITLNNGNKIPSIGFGVFQIPKEETADCVKKAISIGYRLIDTAQAYHNEKETG 60
Query: 241 EAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 411
IK V RE++F+T+K+W + + + ++ E+L L+ YLDL L+H P
Sbjct: 61 LG----IKLSGVKREEIFLTTKVWVSNY--ERCYESVIESLKRLDTSYLDLILLHQP 111
>UniRef50_Q11DV1 Cluster: Aldo/keto reductase; n=10;
Alphaproteobacteria|Rep: Aldo/keto reductase -
Mesorhizobium sp. (strain BNC1)
Length = 274
Score = 79.4 bits (187), Expect = 5e-14
Identities = 36/100 (36%), Positives = 57/100 (57%)
Frame = +1
Query: 112 PILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 291
P LG G ++ EV + + A++ G+RH D A +Y NE +G A+ + REDL
Sbjct: 12 PALGFGVFRMSDAEVERIIPAALEAGFRHFDTAQIYQNEAALGRAL----ERAGARREDL 67
Query: 292 FITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 411
F+T+K+W + D ++ E+L+ L V +DL L+HWP
Sbjct: 68 FLTTKVWVDNYSADKFAASVDESLEKLKVDQVDLLLLHWP 107
>UniRef50_Q6CEJ0 Cluster: Yarrowia lipolytica chromosome B of strain
CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome B of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 302
Score = 79.4 bits (187), Expect = 5e-14
Identities = 49/121 (40%), Positives = 67/121 (55%), Gaps = 8/121 (6%)
Frame = +1
Query: 73 SVPFVEFNNELKCPILGLGT---WKSKPGE-----VTQAVKDAIDIGYRHIDCAYVYGNE 228
+VP V+ +N L+ P +G G+ WK PGE + AV AI+ G+ HID A YG E
Sbjct: 2 TVPKVKLSNGLEIPAIGFGSGTKWKRPPGEKEERELIDAVVSAINAGHLHIDTAEFYGTE 61
Query: 229 KEVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHW 408
K++GEA IKE V R+D+F+TSK D + ++ L L Y DL+LIH
Sbjct: 62 KQIGEA----IKESGVPRKDIFLTSKTLFGLLADDPIE-SISNQLKTLQTDYFDLFLIHV 116
Query: 409 P 411
P
Sbjct: 117 P 117
>UniRef50_A3WP89 Cluster: Aldo/keto reductase; n=1; Idiomarina
baltica OS145|Rep: Aldo/keto reductase - Idiomarina
baltica OS145
Length = 263
Score = 79.0 bits (186), Expect = 6e-14
Identities = 42/105 (40%), Positives = 59/105 (56%)
Frame = +1
Query: 112 PILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 291
P G+GT++ + E+T V AID+GY HID A YGNE +VG+A+ T +D+
Sbjct: 3 PQFGMGTFRLEGQELTDLVSAAIDMGYEHIDTAQFYGNEADVGKALAQH------TNKDV 56
Query: 292 FITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKE 426
F+T+K+W V +LQ + D L +DL LIHWP E
Sbjct: 57 FVTTKVWYEKLAYQDVLDSLQVSRDKLQRDTIDLALIHWPSPNDE 101
>UniRef50_Q8EVT8 Cluster: Oxidoreductase-aldo/keto reductase family;
n=1; Mycoplasma penetrans|Rep: Oxidoreductase-aldo/keto
reductase family - Mycoplasma penetrans
Length = 299
Score = 78.6 bits (185), Expect = 9e-14
Identities = 43/113 (38%), Positives = 65/113 (57%), Gaps = 2/113 (1%)
Frame = +1
Query: 79 PFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSK 258
P + N+ + PI+GLGT A+K A++IG R D A +YGNEKEVGE
Sbjct: 35 PLLTLNDGYQIPIIGLGTTSLHNQTCKNAIKAALEIGIRLFDTASLYGNEKEVGET---- 90
Query: 259 IKEGVVTREDLFITSKLW--NTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 411
I+E + R ++F+ +KL+ F P+ A++E L+ LN Y+D+ L+H P
Sbjct: 91 IRESNINRNEIFVITKLYPGAQFANPE---KAIEEALNKLNTDYIDMMLLHHP 140
>UniRef50_UPI0000D56CE5 Cluster: PREDICTED: similar to CG6084-PA,
isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG6084-PA, isoform A - Tribolium castaneum
Length = 493
Score = 78.2 bits (184), Expect = 1e-13
Identities = 55/154 (35%), Positives = 81/154 (52%)
Frame = +1
Query: 64 KMSSVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGE 243
KM +P + NN ++ P+ GL + EV + V+ + YR +DC+ ++ NEK G
Sbjct: 4 KMRDIPIAKLNNGIEIPVFGLAAPQDF-FEV-ENVQLVVSSNYRLMDCS-IFENEKRFGV 60
Query: 244 AITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYK 423
A+ I+ G + R+DLF+ SK T + +LV+ AL +TL L V YLDLYLI P A K
Sbjct: 61 ALQQLIEGGKIRRKDLFLMSKFCCT-NTTNLVKAALLDTLKKLQVAYLDLYLIERPPACK 119
Query: 424 EDGSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKE 525
D + ++TW+AME L E
Sbjct: 120 -----------------DHNLIETWEAMEGLYSE 136
Score = 69.3 bits (162), Expect = 5e-11
Identities = 32/55 (58%), Positives = 40/55 (72%), Gaps = 1/55 (1%)
Frame = +1
Query: 355 ETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTD-QSGKIQFSDVDYVDTWKAMEPL 516
E+L NL + YLD+YL+HWP A KE SL P D ++G SDVD+VDTWKAME +
Sbjct: 271 ESLKNLQLDYLDVYLMHWPHALKEGPSLHPIDPKTGLFIPSDVDFVDTWKAMEKM 325
>UniRef50_Q5V6N9 Cluster: Alcohol dehydrogenase; n=2;
Halobacteriaceae|Rep: Alcohol dehydrogenase - Haloarcula
marismortui (Halobacterium marismortui)
Length = 667
Score = 78.2 bits (184), Expect = 1e-13
Identities = 47/160 (29%), Positives = 74/160 (46%), Gaps = 18/160 (11%)
Frame = +1
Query: 103 LKCPILGLGTWKSKPG---EVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 273
++ P +G G + + G + ++ A+D GYR +D A +YGNE +G + + G
Sbjct: 376 IRLPAIGFGCSRYRDGTYIDRADSIAAALDAGYRLLDSAELYGNEHRIGRILAAP---GA 432
Query: 274 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSL----- 438
R +FI K+W T HR + A + +LD L + D Y +HWP+A GSL
Sbjct: 433 PDRRRVFILGKVWRTNHRRKHMLTACRSSLDELGIDAFDCYALHWPEALAHRGSLTRLAE 492
Query: 439 ----------FPTDQSGKIQFSDVDYVDTWKAMEPLVKEG 528
FP + G I+ V W+ +E L + G
Sbjct: 493 KSVARQEALTFPKNDRGDIETDSVSLQRAWENLEALHERG 532
>UniRef50_Q1DLF1 Cluster: Putative uncharacterized protein; n=1;
Coccidioides immitis|Rep: Putative uncharacterized
protein - Coccidioides immitis
Length = 324
Score = 77.8 bits (183), Expect = 1e-13
Identities = 53/157 (33%), Positives = 77/157 (49%), Gaps = 9/157 (5%)
Frame = +1
Query: 94 NNELKCPILGLGTWKSKP-----GEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSK 258
N ++ P GLGT++ P G V +V A+ IGYRHID A YG V I +
Sbjct: 11 NTSIRIPARGLGTFQVDPSLYPEGSVKDSVLHALKIGYRHIDAALAYG-WGSVERGIGAA 69
Query: 259 IKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSL 438
I+ V RED+F+ +KL N FH P+ V + +L NL + Y+ P AY + +
Sbjct: 70 IRASGVPREDVFVVTKLHNCFHAPEDVEVGMNMSLKNLGLGYV-------PYAYTKGENY 122
Query: 439 FPTDQSGKIQFSDVD----YVDTWKAMEPLVKEGSGQ 537
+ D++ + TWKAME LV +G +
Sbjct: 123 STVRKPDGKPVVDIELSRAFDTTWKAMENLVDQGKAK 159
>UniRef50_UPI00006CA3CB Cluster: oxidoreductase, aldo/keto reductase
family protein; n=3; Tetrahymena thermophila SB210|Rep:
oxidoreductase, aldo/keto reductase family protein -
Tetrahymena thermophila SB210
Length = 299
Score = 77.0 bits (181), Expect = 3e-13
Identities = 43/116 (37%), Positives = 64/116 (55%), Gaps = 1/116 (0%)
Frame = +1
Query: 85 VEFNNELKCPILGLGTWKSKP-GEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 261
+ +N K P GLG+ + + EVT ++ A+D+GYRHID A +Y NE+ +G A+ +
Sbjct: 10 ITLSNGQKMPAFGLGSSRVQSVEEVTNLIRKALDVGYRHIDTAQMYENEQFIGAALKTIF 69
Query: 262 KEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKED 429
EG RED+F+ +K + ++E L L V Y+DL LIH P A D
Sbjct: 70 GEGKYKREDIFLVTK--QASIKGVSCLEIMKEQLQKLQVDYVDLLLIHVPLAAPSD 123
>UniRef50_Q927E1 Cluster: Lin2848 protein; n=13; Listeria|Rep:
Lin2848 protein - Listeria innocua
Length = 280
Score = 77.0 bits (181), Expect = 3e-13
Identities = 38/108 (35%), Positives = 62/108 (57%), Gaps = 1/108 (0%)
Frame = +1
Query: 94 NNELKCPILGLGTWK-SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEG 270
NN ++ P G G +K + + A++ A+D+GYR D A Y NEKE+G+ S
Sbjct: 12 NNGIEMPRHGFGVYKLTDEQRMRTALETAVDVGYRLFDTASFYHNEKELGDFFASS---- 67
Query: 271 VVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQ 414
+ R++ F+T+K+WNT D A +++ L + +DLYL+HWP+
Sbjct: 68 GLKRDEFFVTTKMWNTEQGYDETLRAFEKSQKKLQLDQVDLYLVHWPK 115
>UniRef50_Q8EUH6 Cluster: Oxidoreductase; n=1; Mycoplasma
penetrans|Rep: Oxidoreductase - Mycoplasma penetrans
Length = 285
Score = 77.0 bits (181), Expect = 3e-13
Identities = 42/111 (37%), Positives = 65/111 (58%), Gaps = 1/111 (0%)
Frame = +1
Query: 82 FVEFNNELKCPILGLGTWKSKPGEVTQAVKDAID-IGYRHIDCAYVYGNEKEVGEAITSK 258
+++ N L PI+GLG +K++ + AID GYR ID A VY NE+ VG AI
Sbjct: 3 YIKLANGLHMPIIGLGVYKAEGENCENTIIKAIDDYGYRMIDTAQVYFNEEFVGNAI--- 59
Query: 259 IKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 411
K+ + RED+FIT+K+W + + + ++ ++L L Y+DL L+H P
Sbjct: 60 -KQTKIKREDIFITTKVWISNYGYNNTMYSISKSLKKLQTNYIDLVLLHQP 109
>UniRef50_Q3CZS2 Cluster: Oxidoreductase, aldo/keto reductase
family; n=2; Streptococcus agalactiae|Rep:
Oxidoreductase, aldo/keto reductase family -
Streptococcus agalactiae H36B
Length = 245
Score = 77.0 bits (181), Expect = 3e-13
Identities = 43/111 (38%), Positives = 62/111 (55%), Gaps = 1/111 (0%)
Frame = +1
Query: 82 FVEFNNELKCPILGLGTWK-SKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSK 258
F NN +K P LG G ++ P E Q+V DA+ +GYR ID A Y NE+ VG AI
Sbjct: 6 FFILNNGVKIPSLGFGVFQIDDPLECEQSVLDALQVGYRLIDTASGYLNEEAVGRAI--- 62
Query: 259 IKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 411
K+ + R+++F+ +KLW + A+ L L + Y++LYLIH P
Sbjct: 63 -KKSGIPRKEIFVVTKLWIQDASEEKAGPAIDRALKRLQLDYINLYLIHQP 112
>UniRef50_A7D761 Cluster: Aldo/keto reductase; n=2;
Halobacteriaceae|Rep: Aldo/keto reductase - Halorubrum
lacusprofundi ATCC 49239
Length = 665
Score = 77.0 bits (181), Expect = 3e-13
Identities = 46/160 (28%), Positives = 73/160 (45%), Gaps = 18/160 (11%)
Frame = +1
Query: 103 LKCPILGLGTWKSKPGEVTQAVKD---AIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 273
++ P +G G + + GE V A+D GYR +D A +YGNE +GE + + G
Sbjct: 374 IRLPAVGFGCSRYRDGEYVDRVDSIATALDAGYRLLDSAELYGNEHRIGELLAAP---GA 430
Query: 274 VTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSL----- 438
RE +F+ K W T HR + + A + + L + D Y +HWP A + G L
Sbjct: 431 PDRERVFLLGKAWRTNHRREHLLAACAGSREELGIDAFDCYALHWPSALEHRGELNRLAE 490
Query: 439 ----------FPTDQSGKIQFSDVDYVDTWKAMEPLVKEG 528
FP + G+ +DV W+ +E + + G
Sbjct: 491 KPVERQETLTFPEGEDGEPATADVALATAWRNLEAVHERG 530
>UniRef50_Q6F7K7 Cluster: 2,5-diketo-D-gluconate reductase; n=20;
Bacteria|Rep: 2,5-diketo-D-gluconate reductase -
Acinetobacter sp. (strain ADP1)
Length = 297
Score = 76.2 bits (179), Expect = 5e-13
Identities = 40/113 (35%), Positives = 62/113 (54%)
Frame = +1
Query: 73 SVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAIT 252
++P + ++ P LG GT+ K + + A+ GYR +D A+ Y NE VG A+
Sbjct: 21 NIPDLILHDGHSIPALGFGTYTLKGQQGVDTMLRALGHGYRMLDSAFNYENEGAVGAAV- 79
Query: 253 SKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 411
++ + R+++FITSKL H D ++E+L + YLDLYLIHWP
Sbjct: 80 ---RQSGLLRDEIFITSKLPGRHHAYDKAMETIEESLYRMQFDYLDLYLIHWP 129
>UniRef50_P91021 Cluster: Putative uncharacterized protein; n=1;
Caenorhabditis elegans|Rep: Putative uncharacterized
protein - Caenorhabditis elegans
Length = 134
Score = 76.2 bits (179), Expect = 5e-13
Identities = 41/82 (50%), Positives = 50/82 (60%)
Frame = +1
Query: 94 NNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 273
+N P +GLGTW+S +V AVK A+ GY ID A Y NE+ +G AI I EGV
Sbjct: 51 SNAHSMPAVGLGTWQSNAEDVISAVKAAVKNGYSLIDTASGYNNEEFIGTAIKEVIAEGV 110
Query: 274 VTREDLFITSKLWNTFHRPDLV 339
V REDLFIT+K+ N F LV
Sbjct: 111 VKREDLFITTKVPNLFSSLRLV 132
>UniRef50_A7RRF6 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 275
Score = 76.2 bits (179), Expect = 5e-13
Identities = 41/102 (40%), Positives = 58/102 (56%)
Frame = +1
Query: 106 KCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRE 285
K P GLG + QAV A++ GYR ID A Y NEK VGEA+ +E V R
Sbjct: 14 KIPRFGLGLYDLDEKHTKQAVLWALENGYRMIDTAASYNNEKRVGEAL----RESAVPRS 69
Query: 286 DLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 411
++++ +K+++T H + A +L L V Y+DLYLIH+P
Sbjct: 70 EVYLVTKVYHTDHGYEKTMKAYDRSLSALGVDYVDLYLIHFP 111
>UniRef50_Q5V398 Cluster: Oxidoreductase aldo/keto reductase family;
n=1; Haloarcula marismortui|Rep: Oxidoreductase
aldo/keto reductase family - Haloarcula marismortui
(Halobacterium marismortui)
Length = 302
Score = 75.8 bits (178), Expect = 6e-13
Identities = 43/109 (39%), Positives = 60/109 (55%), Gaps = 2/109 (1%)
Frame = +1
Query: 88 EFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKE 267
E N P LG GT+++ + AVK+A+D GY HID A Y NE VG A I++
Sbjct: 13 EQNGTTTVPTLGFGTYRTGGYKCYNAVKNALDCGYTHIDTAMAYENEAAVGRA----IEQ 68
Query: 268 GVVTREDLFITSKLWNTFHRPDLVR--GALQETLDNLNVQYLDLYLIHW 408
V RED+F+T+K+ + R A + L+ L +YLDL L+HW
Sbjct: 69 SSVDREDIFLTTKIKGYPEMVEYERLIEAAKGCLERLGTEYLDLLLVHW 117
>UniRef50_Q8G7K9 Cluster: Dehydrogenase or reductase protein; n=4;
Bifidobacterium|Rep: Dehydrogenase or reductase protein
- Bifidobacterium longum
Length = 289
Score = 75.4 bits (177), Expect = 8e-13
Identities = 39/120 (32%), Positives = 62/120 (51%)
Frame = +1
Query: 61 VKMSSVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVG 240
+ ++VP + + P +GLG + V V+ A++ GYRHID A Y NE VG
Sbjct: 6 INPANVPDIALKDGHSIPQVGLGVLRIDDEGVVPVVESALEAGYRHIDGAAGYNNEAGVG 65
Query: 241 EAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAY 420
A+ + RE L++T+KL ++ D A +L L + Y+D+Y+IHWP +
Sbjct: 66 RALAASGYNKGAKRETLWVTTKLRDSQQGYDSALKAFDNSLKLLQLDYVDMYMIHWPTPF 125
>UniRef50_A3JU52 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=1; Rhodobacterales bacterium HTCC2150|Rep:
2,5-diketo-D-gluconic acid reductase A - Rhodobacterales
bacterium HTCC2150
Length = 334
Score = 74.9 bits (176), Expect = 1e-12
Identities = 44/113 (38%), Positives = 58/113 (51%), Gaps = 7/113 (6%)
Frame = +1
Query: 94 NNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGV 273
N P +G GT+ + + AI GYRHID A Y NEK VG I + ++
Sbjct: 43 NTTTTIPAVGFGTYLISNDDAKSTISAAIQAGYRHIDTASGYQNEKTVGAGIKAGLQSAG 102
Query: 274 VTREDLFITSKLW--NTF--HRPDLVRGALQE---TLDNLNVQYLDLYLIHWP 411
+TR+DLF+T+KLW N P L E +L L + Y+DLYLIH P
Sbjct: 103 ITRKDLFVTAKLWPGNPAWGDAPKTKAQTLDECDASLARLGLDYVDLYLIHAP 155
>UniRef50_A2RMU6 Cluster: Oxidoreductase, aldo/keto reductase
family; n=3; Lactococcus lactis|Rep: Oxidoreductase,
aldo/keto reductase family - Lactococcus lactis subsp.
cremoris (strain MG1363)
Length = 281
Score = 74.9 bits (176), Expect = 1e-12
Identities = 43/99 (43%), Positives = 63/99 (63%), Gaps = 1/99 (1%)
Frame = +1
Query: 112 PILGLGTWKSKPGEVTQ-AVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 288
P GLG ++ GE T+ AVK+A+ +GYRHID A+ Y NE+ VG AI S G+ E
Sbjct: 14 PQFGLGVYQIPEGEATENAVKEALRLGYRHIDTAHAYQNERSVGRAIHS---SGIPISE- 69
Query: 289 LFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIH 405
++ITSKLW + + D A++ L+ LN++ +DL L+H
Sbjct: 70 IWITSKLWPSDY--DDASQAIERMLELLNLKQIDLLLLH 106
>UniRef50_Q9C1X5 Cluster: Xylose and arabinose reductase; n=1;
Schizosaccharomyces pombe|Rep: Xylose and arabinose
reductase - Schizosaccharomyces pombe (Fission yeast)
Length = 283
Score = 74.9 bits (176), Expect = 1e-12
Identities = 45/114 (39%), Positives = 61/114 (53%)
Frame = +1
Query: 85 VEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 264
V N + P +G G + K E V A+D GYRHID A VYGNE G+AI +
Sbjct: 11 VTLTNGMVIPRIGFGAFMLKYNECYGLVTQALDSGYRHIDTAAVYGNEDICGKAIVDWCE 70
Query: 265 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKE 426
+ V R D+F+TSKL N R A++ +L +L Y+DL+LI P K+
Sbjct: 71 KNNVKRTDIFLTSKLANCSDYYS-TRAAIRSSLHHLGT-YIDLFLIQSPAGGKK 122
>UniRef50_Q4DJ59 Cluster: Aldo/keto reductase, putative; n=2;
Trypanosoma|Rep: Aldo/keto reductase, putative -
Trypanosoma cruzi
Length = 322
Score = 74.5 bits (175), Expect = 1e-12
Identities = 50/153 (32%), Positives = 77/153 (50%), Gaps = 1/153 (0%)
Frame = +1
Query: 73 SVPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAIT 252
++P +E + ++ P +G+GT++ E AV A+ +G+R +D A Y NE+ VG A
Sbjct: 14 ALPLLESSGGMRIPHMGVGTYELYGDESRIAVLAALRLGFRLVDTAAGYHNEEHVGAA-- 71
Query: 253 SKIKEGVVTREDLFITSKLW-NTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKED 429
I+E V RE+LF+ K+ +LV ++E++ L + Y D LIHWP
Sbjct: 72 --IEESGVQREELFVVVKIAPKAMASEELVEKGIRESVRKLRIAYADCVLIHWPGC---- 125
Query: 430 GSLFPTDQSGKIQFSDVDYVDTWKAMEPLVKEG 528
G L P + G WK M+ L KEG
Sbjct: 126 GGLKPEEAEGHRAARH----RCWKVMQALKKEG 154
>UniRef50_Q9HM42 Cluster: Alcohol dehydrogenase related protein;
n=1; Thermoplasma acidophilum|Rep: Alcohol dehydrogenase
related protein - Thermoplasma acidophilum
Length = 284
Score = 74.5 bits (175), Expect = 1e-12
Identities = 43/118 (36%), Positives = 63/118 (53%), Gaps = 3/118 (2%)
Frame = +1
Query: 67 MSSVPFVEFNNE-LKCPILGLGTW--KSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEV 237
M+ + EF+ K ++G+GTW + E ++++ A+D G ID A +YG E V
Sbjct: 1 MNGMQTAEFDGTGRKVSVIGVGTWSLEGSRSENVRSIRYALDHGVNFIDTAEMYGTEDIV 60
Query: 238 GEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 411
GEAI REDLFI +K+W T V + +E+L L Y+DLY +HWP
Sbjct: 61 GEAIKG------YRREDLFIATKVWPTHFAYHDVLKSCEESLKKLGTDYVDLYQLHWP 112
>UniRef50_A7BES9 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 282
Score = 74.1 bits (174), Expect = 2e-12
Identities = 39/109 (35%), Positives = 61/109 (55%)
Frame = +1
Query: 85 VEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 264
+ NN + P +GLGT+ +P + AV A+D Y ID A VY NE+ VG + + K
Sbjct: 4 ITLNNGITIPQVGLGTYLLEPDDAQSAVTYALDNDYTLIDTANVYVNERAVGRGMRASSK 63
Query: 265 EGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 411
R+++F+ +KLW +F A++ETL+ L Y+DL ++H P
Sbjct: 64 ----ARDEIFLETKLWPSFFER---ASAVEETLERLGTDYIDLMILHQP 105
>UniRef50_A3T261 Cluster: Putative uncharacterized protein; n=1;
Sulfitobacter sp. NAS-14.1|Rep: Putative uncharacterized
protein - Sulfitobacter sp. NAS-14.1
Length = 274
Score = 74.1 bits (174), Expect = 2e-12
Identities = 36/100 (36%), Positives = 55/100 (55%)
Frame = +1
Query: 112 PILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 291
P LG GT++ + V V A+ G+RHID A Y NE++VGE ++ V R+++
Sbjct: 12 PSLGFGTFQLEQDTVADMVAAALSEGFRHIDTAQAYQNEEQVGEG----LRRADVRRDEV 67
Query: 292 FITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 411
F+T+K+ P+ A +L L Y+DL L+HWP
Sbjct: 68 FLTTKILPEHFSPEAFTAAADASLKRLGTDYVDLLLLHWP 107
>UniRef50_Q5B5R6 Cluster: Putative uncharacterized protein; n=1;
Emericella nidulans|Rep: Putative uncharacterized
protein - Emericella nidulans (Aspergillus nidulans)
Length = 682
Score = 73.7 bits (173), Expect = 2e-12
Identities = 42/98 (42%), Positives = 63/98 (64%), Gaps = 1/98 (1%)
Frame = +1
Query: 112 PILGLGTWKS-KPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTRED 288
P +GLGT ++ KPG V +AV+ A+ GYRHID A G E E+G+A +K+ V+R
Sbjct: 423 PAVGLGTRRAQKPGLVYRAVRSALKTGYRHIDTAMSSGVEHEIGQA----VKDSGVSRSQ 478
Query: 289 LFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLI 402
+++T+KL N +H V+ AL +L L + Y+DLYL+
Sbjct: 479 VWVTTKLDNRWH--TRVQEALDMSLSELGMDYVDLYLM 514
>UniRef50_O14088 Cluster: Xylose and arabinose reductase; n=1;
Schizosaccharomyces pombe|Rep: Xylose and arabinose
reductase - Schizosaccharomyces pombe (Fission yeast)
Length = 275
Score = 73.7 bits (173), Expect = 2e-12
Identities = 39/110 (35%), Positives = 59/110 (53%)
Frame = +1
Query: 82 FVEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKI 261
FV+ NN LKCP G++ + +V A+ GYRHID A +Y NE + G AI +
Sbjct: 5 FVKLNNGLKCPQFAYGSYMVNRTKCFDSVYAALQCGYRHIDSAQMYHNEADCGRAILKFM 64
Query: 262 KEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 411
+E RED++ TSKL N ++ ++ + Y+DL+L+H P
Sbjct: 65 EETGTKREDIWFTSKL-NDLSGYKSTLSSIDASVKACGLGYIDLFLLHSP 113
>UniRef50_Q7M4N1 Cluster: Dihydrodiol dehydrogenase DD2; n=2; Homo
sapiens|Rep: Dihydrodiol dehydrogenase DD2 - Homo
sapiens (Human)
Length = 188
Score = 70.9 bits (166), Expect(2) = 4e-12
Identities = 34/68 (50%), Positives = 47/68 (69%)
Frame = +1
Query: 175 AIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQ 354
AI+ G+ HID A+VY NE++VG I +G V RED+F TSKLW+ HRP+LVR AL+
Sbjct: 2 AIEAGFHHIDSAHVYNNEEQVG------IADGSVKREDIFYTSKLWSNSHRPELVRPALE 55
Query: 355 ETLDNLNV 378
D +++
Sbjct: 56 ILFDTVDL 63
Score = 22.2 bits (45), Expect(2) = 4e-12
Identities = 9/17 (52%), Positives = 11/17 (64%)
Frame = +1
Query: 460 KIQFSDVDYVDTWKAME 510
+I F VD TW+AME
Sbjct: 55 EILFDTVDLCATWEAME 71
>UniRef50_A7D6Q0 Cluster: Aldo/keto reductase; n=1; Halorubrum
lacusprofundi ATCC 49239|Rep: Aldo/keto reductase -
Halorubrum lacusprofundi ATCC 49239
Length = 309
Score = 72.5 bits (170), Expect = 6e-12
Identities = 39/101 (38%), Positives = 57/101 (56%), Gaps = 1/101 (0%)
Frame = +1
Query: 112 PILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 291
P LGLGT+ ++ +V+ A+ GY HID A Y NE+ +GE + R+D+
Sbjct: 46 PALGLGTYALDDDQIADSVRAALSSGYTHIDTAEGYHNEEAIGEVLAE------YDRDDV 99
Query: 292 FITSK-LWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 411
F+TSK L L++ + + +L+ L YLDLYLIHWP
Sbjct: 100 FLTSKVLAKNLGYESLIQ-SCEASLERLETDYLDLYLIHWP 139
>UniRef50_Q6WGK4 Cluster: Aldose reductase; n=1; Pristionchus
pacificus|Rep: Aldose reductase - Pristionchus pacificus
Length = 293
Score = 72.1 bits (169), Expect = 7e-12
Identities = 35/103 (33%), Positives = 60/103 (58%), Gaps = 1/103 (0%)
Frame = +1
Query: 106 KCPILGLGTWKSKPGEV-TQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTR 282
+ P++G+GT++ + V T + +A +GYR ID A +Y NE +G + +++ + R
Sbjct: 15 RMPMIGVGTYQVQSQSVLTDTIDEAFRLGYRFIDTAQIYRNEAILGRILPDLLEKHSLKR 74
Query: 283 EDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWP 411
ED+FITSK+ ++ ++L +L Y+DL LIHWP
Sbjct: 75 EDIFITSKVSPINQGKGKTSKSVLKSLTDLQTPYIDLVLIHWP 117
>UniRef50_Q09632 Cluster: Probable oxidoreductase ZK1290.5; n=2;
Caenorhabditis|Rep: Probable oxidoreductase ZK1290.5 -
Caenorhabditis elegans
Length = 321
Score = 72.1 bits (169), Expect = 7e-12
Identities = 45/114 (39%), Positives = 64/114 (56%), Gaps = 1/114 (0%)
Frame = +1
Query: 76 VPFVEFNNELKCPILGLGTWKSKPGEVTQAVKDAID-IGYRHIDCAYVYGNEKEVGEAIT 252
+P +N ++ P++GLGT S G AV +I GYR ID A YG EK++G A+
Sbjct: 2 IPTTVLSNNVEMPLIGLGTTHSG-GYYHDAVLHSIKKCGYRLIDTAKRYGVEKQLGIAV- 59
Query: 253 SKIKEGVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQ 414
K V RE++F+++KLW D V A Q + + L YLD+Y+IH PQ
Sbjct: 60 ---KNCSVPREEMFLSTKLWPV-DCGDEVYNAFQTSCEKLQTDYLDMYMIHMPQ 109
>UniRef50_Q4Q973 Cluster: Aldo/keto reductase, putative; n=3;
Leishmania|Rep: Aldo/keto reductase, putative -
Leishmania major
Length = 414
Score = 71.7 bits (168), Expect = 1e-11
Identities = 43/117 (36%), Positives = 62/117 (52%), Gaps = 1/117 (0%)
Frame = +1
Query: 112 PILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIKEGVVTREDL 291
P +G+GT++ + AV+ A+ +GYR ID A Y NE+ VGE I+S V R DL
Sbjct: 21 PPIGIGTYELRGDACVSAVRAALQMGYRLIDTAAAYRNEELVGEGISS----SGVPRADL 76
Query: 292 FITSKL-WNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKEDGSLFPTDQSG 459
FI K+ + + VR + +++ L + Y D L+HWP G L P D SG
Sbjct: 77 FIVVKIAMKSMSSDEAVRQGILDSIRKLRIDYADCVLMHWPGC----GGLKPQDASG 129
>UniRef50_Q9P734 Cluster: Related to 2, 5-diketo-D-gluconic acid
reductase; n=5; Pezizomycotina|Rep: Related to 2,
5-diketo-D-gluconic acid reductase - Neurospora crassa
Length = 289
Score = 71.3 bits (167), Expect = 1e-11
Identities = 41/118 (34%), Positives = 65/118 (55%), Gaps = 4/118 (3%)
Frame = +1
Query: 85 VEFNNELKCPILGLGTWKSKPGEVTQAVKDAIDIGYRHIDCAYVYGNEKEVGEAITSKIK 264
V+ +N L P + LG + E T+AV+ A+ GYR D A Y NE+E G+AI S +
Sbjct: 13 VKLSNGLSIPQIQLGLYMMSGPETTRAVRWALGAGYRGFDSAQWYYNEREAGQAILSFLS 72
Query: 265 E----GVVTREDLFITSKLWNTFHRPDLVRGALQETLDNLNVQYLDLYLIHWPQAYKE 426
+TR+D+ TSKL + D VR ++ +++ + Y+DL+L+H P +E
Sbjct: 73 SPENTAGLTRKDVHFTSKLRDNSTNYDAVRASISKSVKASGLGYIDLFLLHSPLGGRE 130
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 567,613,298
Number of Sequences: 1657284
Number of extensions: 12289660
Number of successful extensions: 45552
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 42407
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 45079
length of database: 575,637,011
effective HSP length: 96
effective length of database: 416,537,747
effective search space used: 34572633001
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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