Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= bmov12d01
(658 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AF263242-1|AAK58523.1| 320|Homo sapiens aldo-keto reductase loo... 113 2e-36
BC002862-1|AAH02862.1| 307|Homo sapiens AKR1CL2 protein protein. 113 2e-36
AB055603-1|BAC54568.1| 307|Homo sapiens aldo-keto reductase rel... 113 2e-36
CR542203-1|CAG47000.1| 316|Homo sapiens AKR1B1 protein. 151 3e-36
X15414-1|CAA33460.1| 316|Homo sapiens protein ( Human mRNA for ... 149 1e-35
M59783-1|AAA51712.1| 316|Homo sapiens aldose reductase protein. 149 1e-35
M34720-1|AAA35560.1| 316|Homo sapiens protein ( Human aldose re... 149 1e-35
J05474-1|AAA51715.1| 316|Homo sapiens aldose reductase protein. 149 1e-35
J04795-1|AAA51713.1| 316|Homo sapiens ALDR1 protein. 149 1e-35
J04794-1|AAA51711.1| 325|Homo sapiens ALDR1 protein. 149 1e-35
CR457010-1|CAG33291.1| 325|Homo sapiens AKR1A1 protein. 149 1e-35
CR450351-1|CAG29347.1| 316|Homo sapiens AKR1B1 protein. 149 1e-35
BT019859-1|AAV38662.1| 316|Homo sapiens aldo-keto reductase fam... 149 1e-35
BT007003-1|AAP35649.1| 325|Homo sapiens aldo-keto reductase fam... 149 1e-35
BC010391-1|AAH10391.1| 316|Homo sapiens aldo-keto reductase fam... 149 1e-35
BC005394-1|AAH05394.1| 325|Homo sapiens aldo-keto reductase fam... 149 1e-35
BC000670-1|AAH00670.1| 325|Homo sapiens aldo-keto reductase fam... 149 1e-35
BC000260-1|AAH00260.1| 316|Homo sapiens aldo-keto reductase fam... 149 1e-35
AL355480-3|CAI22459.1| 325|Homo sapiens aldo-keto reductase fam... 149 1e-35
AF328729-1|AAN09721.1| 316|Homo sapiens CTCL tumor antigen HD-C... 149 1e-35
AF112485-1|AAF01260.1| 325|Homo sapiens aldehyde reductase prot... 149 1e-35
AF036683-1|AAB92369.1| 325|Homo sapiens aldehyde reductase prot... 149 1e-35
AF032455-1|AAB88851.1| 316|Homo sapiens aldose reductase protein. 149 1e-35
AB209796-1|BAD93033.1| 260|Homo sapiens aldo-keto reductase fam... 149 1e-35
J05017-1|AAA51714.1| 316|Homo sapiens ALDR1 protein. 148 2e-35
AB040821-1|BAC54566.1| 263|Homo sapiens aldo-keto reductase rel... 113 5e-35
AB040820-1|BAC54565.1| 250|Homo sapiens aldo-keto reductase rel... 113 5e-35
AF149416-1|AAF07272.2| 323|Homo sapiens 3-alpha hydroxysteroid ... 145 1e-34
D17793-1|BAA04619.2| 325|Homo sapiens KIAA0119 protein. 145 1e-34
BT007286-1|AAP35950.1| 323|Homo sapiens aldo-keto reductase fam... 145 1e-34
BC019230-1|AAH19230.1| 323|Homo sapiens aldo-keto reductase fam... 145 1e-34
BC001479-1|AAH01479.1| 323|Homo sapiens aldo-keto reductase fam... 145 1e-34
AL391427-4|CAI14729.1| 323|Homo sapiens aldo-keto reductase fam... 145 1e-34
AB032157-1|BAA92892.1| 323|Homo sapiens prostaglandin F synthas... 145 1e-34
AB018580-1|BAA88488.1| 323|Homo sapiens hluPGFS protein. 145 1e-34
S68330-1|AAD14013.1| 323|Homo sapiens chlordecone reductase hom... 143 6e-34
L32592-1|AAB38486.1| 323|Homo sapiens dihydrodiol dehydrogenase... 143 6e-34
BC005387-1|AAH05387.1| 316|Homo sapiens aldo-keto reductase fam... 143 6e-34
U05861-1|AAA18115.1| 323|Homo sapiens hepatic dihydrodiol dehyd... 142 7e-34
U05684-1|AAA16227.1| 323|Homo sapiens dihydrodiol dehydrogenase... 142 7e-34
S68288-1|AAD14011.1| 323|Homo sapiens chlordecone reductase hom... 142 7e-34
M86609-1|AAB02880.1| 323|Homo sapiens dihydrodiol dehydrogenase... 142 7e-34
BT007197-1|AAP35861.1| 323|Homo sapiens aldo-keto reductase fam... 142 7e-34
BC040210-1|AAH40210.1| 323|Homo sapiens aldo-keto reductase fam... 142 7e-34
BC020216-1|AAH20216.1| 323|Homo sapiens aldo-keto reductase fam... 142 7e-34
BC015490-1|AAH15490.1| 323|Homo sapiens aldo-keto reductase fam... 142 7e-34
AL713867-2|CAI16409.1| 323|Homo sapiens aldo-keto reductase fam... 142 7e-34
AB209017-1|BAD92254.1| 286|Homo sapiens aldo-keto reductase fam... 142 7e-34
AB032150-1|BAA92886.1| 323|Homo sapiens 20 alph-hydroxysteroid ... 142 7e-34
AB031083-1|BAA92883.1| 323|Homo sapiens 20 alpha-hydroxysteroid... 142 7e-34
DQ269985-1|ABB76132.1| 323|Homo sapiens type II 3a-hydroxystero... 142 1e-33
L43839-1|AAB41916.1| 323|Homo sapiens 3-alpha-hydroxysteroid de... 142 1e-33
U05598-1|AAA20937.1| 323|Homo sapiens dihydrodiol dehydrogenase... 141 2e-33
BT006653-1|AAP35299.1| 323|Homo sapiens aldo-keto reductase fam... 141 2e-33
BC063574-1|AAH63574.1| 323|Homo sapiens aldo-keto reductase fam... 141 2e-33
BC007024-1|AAH07024.1| 323|Homo sapiens aldo-keto reductase fam... 141 2e-33
AL713867-1|CAI16408.1| 323|Homo sapiens aldo-keto reductase fam... 141 2e-33
AL391427-1|CAI14726.1| 323|Homo sapiens aldo-keto reductase fam... 141 2e-33
AB032153-1|BAA92891.1| 323|Homo sapiens bile acid-binding prote... 141 2e-33
AB031084-1|BAA92884.1| 323|Homo sapiens bile acid-binding prote... 141 2e-33
AB021654-1|BAA36169.1| 323|Homo sapiens DD2/bile acid-binding p... 141 2e-33
S68290-1|AAD14012.1| 320|Homo sapiens chlordecone reductase hom... 135 1e-31
BC020744-1|AAH20744.1| 323|Homo sapiens aldo-keto reductase fam... 134 2e-31
S68287-1|AAD14010.1| 323|Homo sapiens chlordecone reductase pro... 134 3e-31
D26125-1|BAA05122.1| 321|Homo sapiens 3 alpha-hydroxysteroid/di... 134 3e-31
AL355303-2|CAI14202.1| 323|Homo sapiens aldo-keto reductase fam... 134 3e-31
AB045829-1|BAA99542.1| 323|Homo sapiens 3alpha-hydroxysteroid d... 134 3e-31
AB032163-1|BAA92893.1| 323|Homo sapiens dihydrodiol dehydrogena... 134 3e-31
AB031085-1|BAA92885.1| 323|Homo sapiens dihydrodiol dehydrogena... 134 3e-31
U37100-1|AAC17469.1| 316|Homo sapiens aldose reductase-like pep... 132 1e-30
CR541801-1|CAG46600.1| 316|Homo sapiens AKR1B10 protein. 132 1e-30
BT006794-1|AAP35440.1| 316|Homo sapiens aldo-keto reductase fam... 132 1e-30
BC008837-1|AAH08837.1| 316|Homo sapiens aldo-keto reductase fam... 132 1e-30
AF052577-1|AAC36465.1| 316|Homo sapiens aldo-keto reductase pro... 132 1e-30
D26124-1|BAA05121.1| 306|Homo sapiens dihydrodiol dehydrogenase... 130 3e-30
AF524864-1|AAO13380.1| 316|Homo sapiens aldo-ketoreductase prot... 129 7e-30
M33375-1|AAA35658.1| 308|Homo sapiens protein ( Human chlordeco... 128 1e-29
Z28339-1|CAA82193.1| 326|Homo sapiens delta 4-3-oxosteroid 5 be... 126 9e-29
BC130627-1|AAI30628.1| 326|Homo sapiens aldo-keto reductase fam... 126 9e-29
BC130625-1|AAI30626.1| 326|Homo sapiens aldo-keto reductase fam... 126 9e-29
AF283659-1|AAG39381.1| 326|Homo sapiens 5-beta steroid reductas... 126 9e-29
AL713867-3|CAI16410.1| 247|Homo sapiens aldo-keto reductase fam... 107 2e-25
AB040822-1|BAC54567.1| 222|Homo sapiens aldo-keto reductase rel... 113 4e-25
AL355480-2|CAI22458.1| 147|Homo sapiens aldo-keto reductase fam... 112 1e-24
BC101205-1|AAI01206.1| 129|Homo sapiens aldo-keto reductase fam... 107 3e-23
BC101204-1|AAI01205.1| 129|Homo sapiens aldo-keto reductase fam... 107 3e-23
AL391427-2|CAI14727.1| 302|Homo sapiens aldo-keto reductase fam... 107 3e-23
AL355303-1|CAI14201.1| 302|Homo sapiens aldo-keto reductase fam... 107 3e-23
AK131335-1|BAD18494.1| 129|Homo sapiens protein ( Homo sapiens ... 107 3e-23
AB037902-1|BAA92887.1| 130|Homo sapiens truncated aldo-keto red... 107 5e-23
AK058142-1|BAB71682.1| 146|Homo sapiens protein ( Homo sapiens ... 47 7e-05
AB028065-1|BAA88489.1| 67|Homo sapiens prostaglandin F synthas... 45 3e-04
AB037905-2|BAA92890.1| 45|Homo sapiens truncated aldo-keto red... 40 0.008
L35546-1|AAA65028.1| 274|Homo sapiens gamma-glutamylcysteine sy... 37 0.055
CR541833-1|CAG46632.1| 274|Homo sapiens GCLM protein. 37 0.055
BC041809-1|AAH41809.1| 274|Homo sapiens glutamate-cysteine liga... 37 0.055
AY773965-1|AAV28733.1| 274|Homo sapiens glutamate-cysteine liga... 37 0.055
AL117351-10|CAI22976.1| 274|Homo sapiens glutamate-cysteine lig... 37 0.055
AL049796-2|CAI21813.1| 274|Homo sapiens glutamate-cysteine liga... 37 0.055
AF007190-1|AAC02268.1| 513|Homo sapiens intestinal mucin protein. 33 1.2
>AF263242-1|AAK58523.1| 320|Homo sapiens aldo-keto reductase
loopADR protein.
Length = 320
Score = 113 bits (273), Expect(2) = 2e-36
Identities = 52/113 (46%), Positives = 75/113 (66%)
Frame = +1
Query: 136 DMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMK 315
D+PA+GL ++ K+ ++ + V AID GYRHFD A Y E+E+G ++ K
Sbjct: 3 DIPAVGLSSW---------KASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCK 53
Query: 316 VEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 474
++EG V+RED+FI TKLW T H+++ V A SLK L L+Y+DLYL+HWP+G
Sbjct: 54 IKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMG 106
Score = 58.8 bits (136), Expect(2) = 2e-36
Identities = 30/55 (54%), Positives = 37/55 (67%), Gaps = 2/55 (3%)
Frame = +1
Query: 496 SDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEVH 654
SD DF++TW +ED G+VK IG+SNFN +QLER+L K G KP QIE H
Sbjct: 144 SDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECH 198
>BC002862-1|AAH02862.1| 307|Homo sapiens AKR1CL2 protein protein.
Length = 307
Score = 113 bits (273), Expect(2) = 2e-36
Identities = 52/113 (46%), Positives = 75/113 (66%)
Frame = +1
Query: 136 DMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMK 315
D+PA+GL ++ K+ ++ + V AID GYRHFD A Y E+E+G ++ K
Sbjct: 3 DIPAVGLSSW---------KASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCK 53
Query: 316 VEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 474
++EG V+RED+FI TKLW T H+++ V A SLK L L+Y+DLYL+HWP+G
Sbjct: 54 IKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMG 106
Score = 58.8 bits (136), Expect(2) = 2e-36
Identities = 30/55 (54%), Positives = 37/55 (67%), Gaps = 2/55 (3%)
Frame = +1
Query: 496 SDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEVH 654
SD DF++TW +ED G+VK IG+SNFN +QLER+L K G KP QIE H
Sbjct: 144 SDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECH 198
>AB055603-1|BAC54568.1| 307|Homo sapiens aldo-keto reductase
related protein 4 protein.
Length = 307
Score = 113 bits (273), Expect(2) = 2e-36
Identities = 52/113 (46%), Positives = 75/113 (66%)
Frame = +1
Query: 136 DMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMK 315
D+PA+GL ++ K+ ++ + V AID GYRHFD A Y E+E+G ++ K
Sbjct: 3 DIPAVGLSSW---------KASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCK 53
Query: 316 VEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 474
++EG V+RED+FI TKLW T H+++ V A SLK L L+Y+DLYL+HWP+G
Sbjct: 54 IKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMG 106
Score = 58.8 bits (136), Expect(2) = 2e-36
Identities = 30/55 (54%), Positives = 37/55 (67%), Gaps = 2/55 (3%)
Frame = +1
Query: 496 SDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIEVH 654
SD DF++TW +ED G+VK IG+SNFN +QLER+L K G KP QIE H
Sbjct: 144 SDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIECH 198
>CR542203-1|CAG47000.1| 316|Homo sapiens AKR1B1 protein.
Length = 316
Score = 151 bits (365), Expect = 3e-36
Identities = 85/193 (44%), Positives = 113/193 (58%), Gaps = 13/193 (6%)
Frame = +1
Query: 115 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 294
L +NNG MP +GLGT+ KS Q+ + V AIDVGYRH D A VY+ E E+
Sbjct: 5 LLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEV 55
Query: 295 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 474
G A++ K+ E VVKRE++FI +KLW T H + V A +L L LDY+DLYL+HWPIG
Sbjct: 56 GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPIG 115
Query: 475 L-----------NADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG 618
+ + SD + ++TW +E+ G+VK IG+SNFN Q+E +L K G
Sbjct: 116 FKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPG 175
Query: 619 -TIKPDAIQIEVH 654
KP QIE H
Sbjct: 176 LKYKPAVNQIECH 188
>X15414-1|CAA33460.1| 316|Homo sapiens protein ( Human mRNA for
aldose reductase (EC 1.1.1.2). ).
Length = 316
Score = 149 bits (360), Expect = 1e-35
Identities = 84/193 (43%), Positives = 112/193 (58%), Gaps = 13/193 (6%)
Frame = +1
Query: 115 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 294
L +NNG MP +GLGT+ KS Q+ + V AIDVGYRH D A VY+ E E+
Sbjct: 5 LLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEV 55
Query: 295 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 474
G A++ K+ E VVKRE++FI +KLW T H + V A +L L LDY+DLYL+HWP G
Sbjct: 56 GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115
Query: 475 L-----------NADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG 618
+ + SD + ++TW +E+ G+VK IG+SNFN Q+E +L K G
Sbjct: 116 FKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPG 175
Query: 619 -TIKPDAIQIEVH 654
KP QIE H
Sbjct: 176 LKYKPAVNQIECH 188
>M59783-1|AAA51712.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 149 bits (360), Expect = 1e-35
Identities = 84/193 (43%), Positives = 112/193 (58%), Gaps = 13/193 (6%)
Frame = +1
Query: 115 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 294
L +NNG MP +GLGT+ KS Q+ + V AIDVGYRH D A VY+ E E+
Sbjct: 5 LLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEV 55
Query: 295 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 474
G A++ K+ E VVKRE++FI +KLW T H + V A +L L LDY+DLYL+HWP G
Sbjct: 56 GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115
Query: 475 L-----------NADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG 618
+ + SD + ++TW +E+ G+VK IG+SNFN Q+E +L K G
Sbjct: 116 FKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPG 175
Query: 619 -TIKPDAIQIEVH 654
KP QIE H
Sbjct: 176 LKYKPAVNQIECH 188
>M34720-1|AAA35560.1| 316|Homo sapiens protein ( Human aldose
reductase mRNA, complete cds. ).
Length = 316
Score = 149 bits (360), Expect = 1e-35
Identities = 84/193 (43%), Positives = 112/193 (58%), Gaps = 13/193 (6%)
Frame = +1
Query: 115 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 294
L +NNG MP +GLGT+ KS Q+ + V AIDVGYRH D A VY+ E E+
Sbjct: 5 LLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEV 55
Query: 295 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 474
G A++ K+ E VVKRE++FI +KLW T H + V A +L L LDY+DLYL+HWP G
Sbjct: 56 GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115
Query: 475 L-----------NADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG 618
+ + SD + ++TW +E+ G+VK IG+SNFN Q+E +L K G
Sbjct: 116 FKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPG 175
Query: 619 -TIKPDAIQIEVH 654
KP QIE H
Sbjct: 176 LKYKPAVNQIECH 188
>J05474-1|AAA51715.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 149 bits (360), Expect = 1e-35
Identities = 84/193 (43%), Positives = 112/193 (58%), Gaps = 13/193 (6%)
Frame = +1
Query: 115 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 294
L +NNG MP +GLGT+ KS Q+ + V AIDVGYRH D A VY+ E E+
Sbjct: 5 LLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEV 55
Query: 295 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 474
G A++ K+ E VVKRE++FI +KLW T H + V A +L L LDY+DLYL+HWP G
Sbjct: 56 GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115
Query: 475 L-----------NADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG 618
+ + SD + ++TW +E+ G+VK IG+SNFN Q+E +L K G
Sbjct: 116 FKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPG 175
Query: 619 -TIKPDAIQIEVH 654
KP QIE H
Sbjct: 176 LKYKPAVNQIECH 188
>J04795-1|AAA51713.1| 316|Homo sapiens ALDR1 protein.
Length = 316
Score = 149 bits (360), Expect = 1e-35
Identities = 84/193 (43%), Positives = 112/193 (58%), Gaps = 13/193 (6%)
Frame = +1
Query: 115 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 294
L +NNG MP +GLGT+ KS Q+ + V AIDVGYRH D A VY+ E E+
Sbjct: 5 LLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEV 55
Query: 295 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 474
G A++ K+ E VVKRE++FI +KLW T H + V A +L L LDY+DLYL+HWP G
Sbjct: 56 GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115
Query: 475 L-----------NADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG 618
+ + SD + ++TW +E+ G+VK IG+SNFN Q+E +L K G
Sbjct: 116 FKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPG 175
Query: 619 -TIKPDAIQIEVH 654
KP QIE H
Sbjct: 176 LKYKPAVNQIECH 188
>J04794-1|AAA51711.1| 325|Homo sapiens ALDR1 protein.
Length = 325
Score = 149 bits (360), Expect = 1e-35
Identities = 78/197 (39%), Positives = 115/197 (58%), Gaps = 12/197 (6%)
Frame = +1
Query: 100 MEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYE 279
M + ++ G+ MP IGLGT+ KS+ Q++ V A+ VGYRH D A++Y
Sbjct: 1 MAASCVLLHTGQKMPLIGLGTW---------KSEPGQVKAAVKYALSVGYRHIDCAAIYG 51
Query: 280 TEQEIGEAVKMKVEEG-VVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYL 456
E EIGEA+K V G V RE++F+T+KLWNT+H +V A+ +L L L+Y+DLYL
Sbjct: 52 NEPEIGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYL 111
Query: 457 MHWPIGL---------NAD--YSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLER 603
MHWP NAD + + ETW+ LE G+V+ +GLSNFN +Q++
Sbjct: 112 MHWPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDD 171
Query: 604 VLKEGTIKPDAIQIEVH 654
+L +++P +Q+E H
Sbjct: 172 ILSVASVRPAVLQVECH 188
>CR457010-1|CAG33291.1| 325|Homo sapiens AKR1A1 protein.
Length = 325
Score = 149 bits (360), Expect = 1e-35
Identities = 78/197 (39%), Positives = 115/197 (58%), Gaps = 12/197 (6%)
Frame = +1
Query: 100 MEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYE 279
M + ++ G+ MP IGLGT+ KS+ Q++ V A+ VGYRH D A++Y
Sbjct: 1 MAASCVLLHTGQKMPLIGLGTW---------KSEPGQVKAAVKYALSVGYRHIDCAAIYG 51
Query: 280 TEQEIGEAVKMKVEEG-VVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYL 456
E EIGEA+K V G V RE++F+T+KLWNT+H +V A+ +L L L+Y+DLYL
Sbjct: 52 NEPEIGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYL 111
Query: 457 MHWPIGL---------NAD--YSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLER 603
MHWP NAD + + ETW+ LE G+V+ +GLSNFN +Q++
Sbjct: 112 MHWPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDD 171
Query: 604 VLKEGTIKPDAIQIEVH 654
+L +++P +Q+E H
Sbjct: 172 ILSVASVRPAVLQVECH 188
>CR450351-1|CAG29347.1| 316|Homo sapiens AKR1B1 protein.
Length = 316
Score = 149 bits (360), Expect = 1e-35
Identities = 84/193 (43%), Positives = 112/193 (58%), Gaps = 13/193 (6%)
Frame = +1
Query: 115 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 294
L +NNG MP +GLGT+ KS Q+ + V AIDVGYRH D A VY+ E E+
Sbjct: 5 LLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEV 55
Query: 295 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 474
G A++ K+ E VVKRE++FI +KLW T H + V A +L L LDY+DLYL+HWP G
Sbjct: 56 GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115
Query: 475 L-----------NADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG 618
+ + SD + ++TW +E+ G+VK IG+SNFN Q+E +L K G
Sbjct: 116 FRPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILSKPG 175
Query: 619 -TIKPDAIQIEVH 654
KP QIE H
Sbjct: 176 LKYKPAVNQIECH 188
>BT019859-1|AAV38662.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 149 bits (360), Expect = 1e-35
Identities = 84/193 (43%), Positives = 112/193 (58%), Gaps = 13/193 (6%)
Frame = +1
Query: 115 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 294
L +NNG MP +GLGT+ KS Q+ + V AIDVGYRH D A VY+ E E+
Sbjct: 5 LLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEV 55
Query: 295 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 474
G A++ K+ E VVKRE++FI +KLW T H + V A +L L LDY+DLYL+HWP G
Sbjct: 56 GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115
Query: 475 L-----------NADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG 618
+ + SD + ++TW +E+ G+VK IG+SNFN Q+E +L K G
Sbjct: 116 FKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPG 175
Query: 619 -TIKPDAIQIEVH 654
KP QIE H
Sbjct: 176 LKYKPAVNQIECH 188
>BT007003-1|AAP35649.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 149 bits (360), Expect = 1e-35
Identities = 78/197 (39%), Positives = 115/197 (58%), Gaps = 12/197 (6%)
Frame = +1
Query: 100 MEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYE 279
M + ++ G+ MP IGLGT+ KS+ Q++ V A+ VGYRH D A++Y
Sbjct: 1 MAASCVLLHTGQKMPLIGLGTW---------KSEPGQVKAAVKYALSVGYRHIDCAAIYG 51
Query: 280 TEQEIGEAVKMKVEEG-VVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYL 456
E EIGEA+K V G V RE++F+T+KLWNT+H +V A+ +L L L+Y+DLYL
Sbjct: 52 NEPEIGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYL 111
Query: 457 MHWPIGL---------NAD--YSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLER 603
MHWP NAD + + ETW+ LE G+V+ +GLSNFN +Q++
Sbjct: 112 MHWPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDD 171
Query: 604 VLKEGTIKPDAIQIEVH 654
+L +++P +Q+E H
Sbjct: 172 ILSVASVRPAVLQVECH 188
>BC010391-1|AAH10391.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 149 bits (360), Expect = 1e-35
Identities = 84/193 (43%), Positives = 112/193 (58%), Gaps = 13/193 (6%)
Frame = +1
Query: 115 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 294
L +NNG MP +GLGT+ KS Q+ + V AIDVGYRH D A VY+ E E+
Sbjct: 5 LLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEV 55
Query: 295 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 474
G A++ K+ E VVKRE++FI +KLW T H + V A +L L LDY+DLYL+HWP G
Sbjct: 56 GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115
Query: 475 L-----------NADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG 618
+ + SD + ++TW +E+ G+VK IG+SNFN Q+E +L K G
Sbjct: 116 FKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPG 175
Query: 619 -TIKPDAIQIEVH 654
KP QIE H
Sbjct: 176 LKYKPAVNQIECH 188
>BC005394-1|AAH05394.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 149 bits (360), Expect = 1e-35
Identities = 78/197 (39%), Positives = 115/197 (58%), Gaps = 12/197 (6%)
Frame = +1
Query: 100 MEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYE 279
M + ++ G+ MP IGLGT+ KS+ Q++ V A+ VGYRH D A++Y
Sbjct: 1 MAASCVLLHTGQKMPLIGLGTW---------KSEPGQVKAAVKYALSVGYRHIDCAAIYG 51
Query: 280 TEQEIGEAVKMKVEEG-VVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYL 456
E EIGEA+K V G V RE++F+T+KLWNT+H +V A+ +L L L+Y+DLYL
Sbjct: 52 NEPEIGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYL 111
Query: 457 MHWPIGL---------NAD--YSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLER 603
MHWP NAD + + ETW+ LE G+V+ +GLSNFN +Q++
Sbjct: 112 MHWPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDD 171
Query: 604 VLKEGTIKPDAIQIEVH 654
+L +++P +Q+E H
Sbjct: 172 ILSVASVRPAVLQVECH 188
>BC000670-1|AAH00670.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehyde reductase) protein.
Length = 325
Score = 149 bits (360), Expect = 1e-35
Identities = 78/197 (39%), Positives = 115/197 (58%), Gaps = 12/197 (6%)
Frame = +1
Query: 100 MEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYE 279
M + ++ G+ MP IGLGT+ KS+ Q++ V A+ VGYRH D A++Y
Sbjct: 1 MAASCVLLHTGQKMPLIGLGTW---------KSEPGQVKAAVKYALSVGYRHIDCAAIYG 51
Query: 280 TEQEIGEAVKMKVEEG-VVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYL 456
E EIGEA+K V G V RE++F+T+KLWNT+H +V A+ +L L L+Y+DLYL
Sbjct: 52 NEPEIGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYL 111
Query: 457 MHWPIGL---------NAD--YSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLER 603
MHWP NAD + + ETW+ LE G+V+ +GLSNFN +Q++
Sbjct: 112 MHWPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDD 171
Query: 604 VLKEGTIKPDAIQIEVH 654
+L +++P +Q+E H
Sbjct: 172 ILSVASVRPAVLQVECH 188
>BC000260-1|AAH00260.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 149 bits (360), Expect = 1e-35
Identities = 84/193 (43%), Positives = 112/193 (58%), Gaps = 13/193 (6%)
Frame = +1
Query: 115 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 294
L +NNG MP +GLGT+ KS Q+ + V AIDVGYRH D A VY+ E E+
Sbjct: 5 LLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEV 55
Query: 295 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 474
G A++ K+ E VVKRE++FI +KLW T H + V A +L L LDY+DLYL+HWP G
Sbjct: 56 GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115
Query: 475 L-----------NADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG 618
+ + SD + ++TW +E+ G+VK IG+SNFN Q+E +L K G
Sbjct: 116 FKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPG 175
Query: 619 -TIKPDAIQIEVH 654
KP QIE H
Sbjct: 176 LKYKPAVNQIECH 188
>AL355480-3|CAI22459.1| 325|Homo sapiens aldo-keto reductase family
1, member A1 (aldehydetase, 1 protein.
Length = 325
Score = 149 bits (360), Expect = 1e-35
Identities = 78/197 (39%), Positives = 115/197 (58%), Gaps = 12/197 (6%)
Frame = +1
Query: 100 MEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYE 279
M + ++ G+ MP IGLGT+ KS+ Q++ V A+ VGYRH D A++Y
Sbjct: 1 MAASCVLLHTGQKMPLIGLGTW---------KSEPGQVKAAVKYALSVGYRHIDCAAIYG 51
Query: 280 TEQEIGEAVKMKVEEG-VVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYL 456
E EIGEA+K V G V RE++F+T+KLWNT+H +V A+ +L L L+Y+DLYL
Sbjct: 52 NEPEIGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYL 111
Query: 457 MHWPIGL---------NAD--YSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLER 603
MHWP NAD + + ETW+ LE G+V+ +GLSNFN +Q++
Sbjct: 112 MHWPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDD 171
Query: 604 VLKEGTIKPDAIQIEVH 654
+L +++P +Q+E H
Sbjct: 172 ILSVASVRPAVLQVECH 188
>AF328729-1|AAN09721.1| 316|Homo sapiens CTCL tumor antigen
HD-CL-07 protein.
Length = 316
Score = 149 bits (360), Expect = 1e-35
Identities = 84/193 (43%), Positives = 112/193 (58%), Gaps = 13/193 (6%)
Frame = +1
Query: 115 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 294
L +NNG MP +GLGT+ KS Q+ + V AIDVGYRH D A VY+ E E+
Sbjct: 5 LLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEV 55
Query: 295 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 474
G A++ K+ E VVKRE++FI +KLW T H + V A +L L LDY+DLYL+HWP G
Sbjct: 56 GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115
Query: 475 L-----------NADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG 618
+ + SD + ++TW +E+ G+VK IG+SNFN Q+E +L K G
Sbjct: 116 FKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPG 175
Query: 619 -TIKPDAIQIEVH 654
KP QIE H
Sbjct: 176 LKYKPAVNQIECH 188
>AF112485-1|AAF01260.1| 325|Homo sapiens aldehyde reductase
protein.
Length = 325
Score = 149 bits (360), Expect = 1e-35
Identities = 78/197 (39%), Positives = 115/197 (58%), Gaps = 12/197 (6%)
Frame = +1
Query: 100 MEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYE 279
M + ++ G+ MP IGLGT+ KS+ Q++ V A+ VGYRH D A++Y
Sbjct: 1 MAASCVLLHTGQKMPLIGLGTW---------KSEPGQVKAAVKYALSVGYRHIDCAAIYG 51
Query: 280 TEQEIGEAVKMKVEEG-VVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYL 456
E EIGEA+K V G V RE++F+T+KLWNT+H +V A+ +L L L+Y+DLYL
Sbjct: 52 NEPEIGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYL 111
Query: 457 MHWPIGL---------NAD--YSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLER 603
MHWP NAD + + ETW+ LE G+V+ +GLSNFN +Q++
Sbjct: 112 MHWPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDD 171
Query: 604 VLKEGTIKPDAIQIEVH 654
+L +++P +Q+E H
Sbjct: 172 ILSVASVRPAVLQVECH 188
>AF036683-1|AAB92369.1| 325|Homo sapiens aldehyde reductase
protein.
Length = 325
Score = 149 bits (360), Expect = 1e-35
Identities = 78/197 (39%), Positives = 115/197 (58%), Gaps = 12/197 (6%)
Frame = +1
Query: 100 MEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYE 279
M + ++ G+ MP IGLGT+ KS+ Q++ V A+ VGYRH D A++Y
Sbjct: 1 MAASCVLLHTGQKMPLIGLGTW---------KSEPGQVKAAVKYALSVGYRHIDCAAIYG 51
Query: 280 TEQEIGEAVKMKVEEG-VVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYL 456
E EIGEA+K V G V RE++F+T+KLWNT+H +V A+ +L L L+Y+DLYL
Sbjct: 52 NEPEIGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYL 111
Query: 457 MHWPIGL---------NAD--YSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLER 603
MHWP NAD + + ETW+ LE G+V+ +GLSNFN +Q++
Sbjct: 112 MHWPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDD 171
Query: 604 VLKEGTIKPDAIQIEVH 654
+L +++P +Q+E H
Sbjct: 172 ILSVASVRPAVLQVECH 188
>AF032455-1|AAB88851.1| 316|Homo sapiens aldose reductase protein.
Length = 316
Score = 149 bits (360), Expect = 1e-35
Identities = 84/193 (43%), Positives = 112/193 (58%), Gaps = 13/193 (6%)
Frame = +1
Query: 115 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 294
L +NNG MP +GLGT+ KS Q+ + V AIDVGYRH D A VY+ E E+
Sbjct: 5 LLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEV 55
Query: 295 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 474
G A++ K+ E VVKRE++FI +KLW T H + V A +L L LDY+DLYL+HWP G
Sbjct: 56 GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115
Query: 475 L-----------NADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG 618
+ + SD + ++TW +E+ G+VK IG+SNFN Q+E +L K G
Sbjct: 116 FKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPG 175
Query: 619 -TIKPDAIQIEVH 654
KP QIE H
Sbjct: 176 LKYKPAVNQIECH 188
>AB209796-1|BAD93033.1| 260|Homo sapiens aldo-keto reductase family
1, member B1 variant protein.
Length = 260
Score = 149 bits (360), Expect = 1e-35
Identities = 84/193 (43%), Positives = 112/193 (58%), Gaps = 13/193 (6%)
Frame = +1
Query: 115 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 294
L +NNG MP +GLGT+ KS Q+ + V AIDVGYRH D A VY+ E E+
Sbjct: 2 LLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEV 52
Query: 295 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 474
G A++ K+ E VVKRE++FI +KLW T H + V A +L L LDY+DLYL+HWP G
Sbjct: 53 GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 112
Query: 475 L-----------NADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG 618
+ + SD + ++TW +E+ G+VK IG+SNFN Q+E +L K G
Sbjct: 113 FKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPG 172
Query: 619 -TIKPDAIQIEVH 654
KP QIE H
Sbjct: 173 LKYKPAVNQIECH 185
>J05017-1|AAA51714.1| 316|Homo sapiens ALDR1 protein.
Length = 316
Score = 148 bits (358), Expect = 2e-35
Identities = 83/191 (43%), Positives = 111/191 (58%), Gaps = 13/191 (6%)
Frame = +1
Query: 121 MNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGE 300
+NNG MP +GLGT+ KS Q+ + V AIDVGYRH D A VY+ E E+G
Sbjct: 7 LNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGV 57
Query: 301 AVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL- 477
A++ K+ E VVKRE++FI +KLW T H + V A +L L LDY+DLYL+HWP G
Sbjct: 58 AIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFK 117
Query: 478 ----------NADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-T 621
+ + SD + ++TW +E+ G+VK IG+SNFN Q+E +L K G
Sbjct: 118 PGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLK 177
Query: 622 IKPDAIQIEVH 654
KP QIE H
Sbjct: 178 YKPAVNQIECH 188
>AB040821-1|BAC54566.1| 263|Homo sapiens aldo-keto reductase
related protein 2 protein.
Length = 263
Score = 113 bits (273), Expect(2) = 5e-35
Identities = 52/113 (46%), Positives = 75/113 (66%)
Frame = +1
Query: 136 DMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMK 315
D+PA+GL ++ K+ ++ + V AID GYRHFD A Y E+E+G ++ K
Sbjct: 3 DIPAVGLSSW---------KASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCK 53
Query: 316 VEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 474
++EG V+RED+FI TKLW T H+++ V A SLK L L+Y+DLYL+HWP+G
Sbjct: 54 IKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMG 106
Score = 54.0 bits (124), Expect(2) = 5e-35
Identities = 22/40 (55%), Positives = 30/40 (75%)
Frame = +1
Query: 496 SDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKE 615
SD DF++TW +ED G+VK IG+SNFN +QLER+L +
Sbjct: 144 SDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNK 183
>AB040820-1|BAC54565.1| 250|Homo sapiens aldo-keto reductase
related protein 1 protein.
Length = 250
Score = 113 bits (273), Expect(2) = 5e-35
Identities = 52/113 (46%), Positives = 75/113 (66%)
Frame = +1
Query: 136 DMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMK 315
D+PA+GL ++ K+ ++ + V AID GYRHFD A Y E+E+G ++ K
Sbjct: 3 DIPAVGLSSW---------KASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCK 53
Query: 316 VEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 474
++EG V+RED+FI TKLW T H+++ V A SLK L L+Y+DLYL+HWP+G
Sbjct: 54 IKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMG 106
Score = 54.0 bits (124), Expect(2) = 5e-35
Identities = 22/40 (55%), Positives = 30/40 (75%)
Frame = +1
Query: 496 SDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKE 615
SD DF++TW +ED G+VK IG+SNFN +QLER+L +
Sbjct: 144 SDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNK 183
>AF149416-1|AAF07272.2| 323|Homo sapiens 3-alpha hydroxysteroid
dehydrogenase type IIb protein.
Length = 323
Score = 145 bits (352), Expect = 1e-34
Identities = 81/193 (41%), Positives = 118/193 (61%), Gaps = 13/193 (6%)
Frame = +1
Query: 115 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 294
+K+N+G MP +G GTY + V +SK ++ + AI+ G+RH D+A +Y E+++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPE---VPRSKALEVSKL---AIEAGFRHIDSAHLYNNEEQV 61
Query: 295 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 474
G A++ K+ +G VKREDIF T+KLW+T HR V A+ +SLKK LDY+DLYL+H P+
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWSTSHRPELVRPALENSLKKAQLDYVDLYLIHSPMS 121
Query: 475 L--NADYSHSD---------VDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG 618
L + S +D VD TW +E + G+ K IG+SNFN++QLE +L K G
Sbjct: 122 LKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPG 181
Query: 619 -TIKPDAIQIEVH 654
KP Q+E H
Sbjct: 182 LKYKPVCNQVECH 194
>D17793-1|BAA04619.2| 325|Homo sapiens KIAA0119 protein.
Length = 325
Score = 145 bits (351), Expect = 1e-34
Identities = 82/193 (42%), Positives = 117/193 (60%), Gaps = 13/193 (6%)
Frame = +1
Query: 115 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 294
+K+N+G MP +G GTY + V +SK +V AI+ G+RH D+A +Y E+++
Sbjct: 10 VKLNDGHFMPVLGFGTYAPPE---VPRSK---ALEVTKLAIEAGFRHIDSAHLYNNEEQV 63
Query: 295 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 474
G A++ K+ +G VKREDIF T+KLW+T HR V A+ +SLKK LDY+DLYL+H P+
Sbjct: 64 GLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMS 123
Query: 475 L--NADYSHSD---------VDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG 618
L + S +D VD TW +E + G+ K IG+SNFN++QLE +L K G
Sbjct: 124 LKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPG 183
Query: 619 -TIKPDAIQIEVH 654
KP Q+E H
Sbjct: 184 LKYKPVCNQVECH 196
>BT007286-1|AAP35950.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 145 bits (351), Expect = 1e-34
Identities = 82/193 (42%), Positives = 117/193 (60%), Gaps = 13/193 (6%)
Frame = +1
Query: 115 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 294
+K+N+G MP +G GTY + V +SK +V AI+ G+RH D+A +Y E+++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPE---VPRSK---ALEVTKLAIEAGFRHIDSAHLYNNEEQV 61
Query: 295 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 474
G A++ K+ +G VKREDIF T+KLW+T HR V A+ +SLKK LDY+DLYL+H P+
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMS 121
Query: 475 L--NADYSHSD---------VDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG 618
L + S +D VD TW +E + G+ K IG+SNFN++QLE +L K G
Sbjct: 122 LKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPG 181
Query: 619 -TIKPDAIQIEVH 654
KP Q+E H
Sbjct: 182 LKYKPVCNQVECH 194
>BC019230-1|AAH19230.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 145 bits (351), Expect = 1e-34
Identities = 82/193 (42%), Positives = 117/193 (60%), Gaps = 13/193 (6%)
Frame = +1
Query: 115 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 294
+K+N+G MP +G GTY + V +SK +V AI+ G+RH D+A +Y E+++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPE---VPRSK---ALEVTKLAIEAGFRHIDSAHLYNNEEQV 61
Query: 295 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 474
G A++ K+ +G VKREDIF T+KLW+T HR V A+ +SLKK LDY+DLYL+H P+
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMS 121
Query: 475 L--NADYSHSD---------VDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG 618
L + S +D VD TW +E + G+ K IG+SNFN++QLE +L K G
Sbjct: 122 LKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPG 181
Query: 619 -TIKPDAIQIEVH 654
KP Q+E H
Sbjct: 182 LKYKPVCNQVECH 194
>BC001479-1|AAH01479.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 145 bits (351), Expect = 1e-34
Identities = 82/193 (42%), Positives = 117/193 (60%), Gaps = 13/193 (6%)
Frame = +1
Query: 115 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 294
+K+N+G MP +G GTY + V +SK +V AI+ G+RH D+A +Y E+++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPE---VPRSK---ALEVTKLAIEAGFRHIDSAHLYNNEEQV 61
Query: 295 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 474
G A++ K+ +G VKREDIF T+KLW+T HR V A+ +SLKK LDY+DLYL+H P+
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMS 121
Query: 475 L--NADYSHSD---------VDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG 618
L + S +D VD TW +E + G+ K IG+SNFN++QLE +L K G
Sbjct: 122 LKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPG 181
Query: 619 -TIKPDAIQIEVH 654
KP Q+E H
Sbjct: 182 LKYKPVCNQVECH 194
>AL391427-4|CAI14729.1| 323|Homo sapiens aldo-keto reductase family
1, member C3 (3-alpha hydroxysteroid dehydrogenase,
protein.
Length = 323
Score = 145 bits (351), Expect = 1e-34
Identities = 82/193 (42%), Positives = 117/193 (60%), Gaps = 13/193 (6%)
Frame = +1
Query: 115 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 294
+K+N+G MP +G GTY + V +SK +V AI+ G+RH D+A +Y E+++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPE---VPRSK---ALEVTKLAIEAGFRHIDSAHLYNNEEQV 61
Query: 295 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 474
G A++ K+ +G VKREDIF T+KLW+T HR V A+ +SLKK LDY+DLYL+H P+
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMS 121
Query: 475 L--NADYSHSD---------VDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG 618
L + S +D VD TW +E + G+ K IG+SNFN++QLE +L K G
Sbjct: 122 LKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPG 181
Query: 619 -TIKPDAIQIEVH 654
KP Q+E H
Sbjct: 182 LKYKPVCNQVECH 194
>AB032157-1|BAA92892.1| 323|Homo sapiens prostaglandin F synthase
protein.
Length = 323
Score = 145 bits (351), Expect = 1e-34
Identities = 82/193 (42%), Positives = 117/193 (60%), Gaps = 13/193 (6%)
Frame = +1
Query: 115 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 294
+K+N+G MP +G GTY + V +SK +V AI+ G+RH D+A +Y E+++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPE---VPRSK---ALEVTKLAIEAGFRHIDSAHLYNNEEQV 61
Query: 295 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 474
G A++ K+ +G VKREDIF T+KLW+T HR V A+ +SLKK LDY+DLYL+H P+
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMS 121
Query: 475 L--NADYSHSD---------VDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG 618
L + S +D VD TW +E + G+ K IG+SNFN++QLE +L K G
Sbjct: 122 LKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPG 181
Query: 619 -TIKPDAIQIEVH 654
KP Q+E H
Sbjct: 182 LKYKPVCNQVECH 194
>AB018580-1|BAA88488.1| 323|Homo sapiens hluPGFS protein.
Length = 323
Score = 145 bits (351), Expect = 1e-34
Identities = 82/193 (42%), Positives = 117/193 (60%), Gaps = 13/193 (6%)
Frame = +1
Query: 115 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 294
+K+N+G MP +G GTY + V +SK +V AI+ G+RH D+A +Y E+++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPE---VPRSK---ALEVTKLAIEAGFRHIDSAHLYNNEEQV 61
Query: 295 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 474
G A++ K+ +G VKREDIF T+KLW+T HR V A+ +SLKK LDY+DLYL+H P+
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMS 121
Query: 475 L--NADYSHSD---------VDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG 618
L + S +D VD TW +E + G+ K IG+SNFN++QLE +L K G
Sbjct: 122 LKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPG 181
Query: 619 -TIKPDAIQIEVH 654
KP Q+E H
Sbjct: 182 LKYKPVCNQVECH 194
>S68330-1|AAD14013.1| 323|Homo sapiens chlordecone reductase
homolog protein.
Length = 323
Score = 143 bits (346), Expect = 6e-34
Identities = 78/193 (40%), Positives = 110/193 (56%), Gaps = 13/193 (6%)
Frame = +1
Query: 115 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 294
+K+N+G MP +G GTY + V KSK + V AI+ G+ H D+A VY E+++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAE---VPKSK---ALEAVKLAIEAGFHHIDSAHVYNNEEQV 61
Query: 295 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 474
G A++ K+ +G VKREDIF T+KLW+ HR V A+ SLK L LDY+DLYL+H+P+
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 475 L-----------NADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGT 621
+ N VD TW +E + G+ K IG+SNFN + LE +L E
Sbjct: 122 VKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNEPG 181
Query: 622 IK--PDAIQIEVH 654
+K P Q+E H
Sbjct: 182 LKYEPVCNQVECH 194
>L32592-1|AAB38486.1| 323|Homo sapiens dihydrodiol
dehydrogenase/bile acid-binding protein protein.
Length = 323
Score = 143 bits (346), Expect = 6e-34
Identities = 79/193 (40%), Positives = 109/193 (56%), Gaps = 13/193 (6%)
Frame = +1
Query: 115 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 294
+K+N+G MP +G GTY + V KSK + V AI+ GY H D+A VY E+++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAE---VPKSK---ALEAVKLAIEAGYHHIDSAHVYNNEEQV 61
Query: 295 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 474
G A++ K+ +G VKREDIF T+KLW+ HR V A+ SLK L LDY DLYL+H+P+
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYADLYLIHFPVS 121
Query: 475 L-----------NADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGT 621
+ N VD TW +E + G+ K IG+SNFN + LE +L E
Sbjct: 122 VKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNEPG 181
Query: 622 IK--PDAIQIEVH 654
+K P Q+E H
Sbjct: 182 LKYEPVCNQVECH 194
>BC005387-1|AAH05387.1| 316|Homo sapiens aldo-keto reductase family
1, member B1 (aldose reductase) protein.
Length = 316
Score = 143 bits (346), Expect = 6e-34
Identities = 83/193 (43%), Positives = 111/193 (57%), Gaps = 13/193 (6%)
Frame = +1
Query: 115 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 294
L +NNG MP +GLGT+ KS Q+ + V AIDVGYRH D A VY+ E E+
Sbjct: 5 LLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEV 55
Query: 295 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 474
G A++ K+ E VVKRE++FI +KLW T H + V A +L L LDY+DLYL+HWP G
Sbjct: 56 GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115
Query: 475 L-----------NADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG 618
+ + SD + ++T +E+ G+VK IG+SNFN Q+E +L K G
Sbjct: 116 FKPGKEFFPLDESGNVVPSDTNILDTRAAMEELVDEGLVKAIGISNFNHLQVEMILNKPG 175
Query: 619 -TIKPDAIQIEVH 654
KP QIE H
Sbjct: 176 LKYKPAVNQIECH 188
>U05861-1|AAA18115.1| 323|Homo sapiens hepatic dihydrodiol
dehydrogenase protein.
Length = 323
Score = 142 bits (345), Expect = 7e-34
Identities = 79/193 (40%), Positives = 112/193 (58%), Gaps = 13/193 (6%)
Frame = +1
Query: 115 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 294
+K+N+G MP +G GTY + V KSK + + AI+ G+RH D+A +Y E+++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAE---VPKSKALEATKL---AIEAGFRHIDSAHLYNNEEQV 61
Query: 295 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 474
G A++ K+ +G VKREDIF T+KLW HR V A+ SLK L LDY+DLYL+H+P+
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 475 L-----------NADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG 618
+ N VD TW +E + G+ K IG+SNFN++QLE +L K G
Sbjct: 122 VKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPG 181
Query: 619 -TIKPDAIQIEVH 654
KP Q+E H
Sbjct: 182 LKYKPVCNQVECH 194
>U05684-1|AAA16227.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 142 bits (345), Expect = 7e-34
Identities = 79/193 (40%), Positives = 112/193 (58%), Gaps = 13/193 (6%)
Frame = +1
Query: 115 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 294
+K+N+G MP +G GTY + V KSK + + AI+ G+RH D+A +Y E+++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAE---VPKSKALEATKL---AIEAGFRHIDSAHLYNNEEQV 61
Query: 295 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 474
G A++ K+ +G VKREDIF T+KLW HR V A+ SLK L LDY+DLYL+H+P+
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 475 L-----------NADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG 618
+ N VD TW +E + G+ K IG+SNFN++QLE +L K G
Sbjct: 122 VKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPG 181
Query: 619 -TIKPDAIQIEVH 654
KP Q+E H
Sbjct: 182 LKYKPVCNQVECH 194
>S68288-1|AAD14011.1| 323|Homo sapiens chlordecone reductase
homolog protein.
Length = 323
Score = 142 bits (345), Expect = 7e-34
Identities = 81/193 (41%), Positives = 117/193 (60%), Gaps = 13/193 (6%)
Frame = +1
Query: 115 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 294
+K+N+G MP +G GTY + V +SK +V AI+ G+RH D+A +Y E+++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPE---VPRSK---ALEVTKLAIEAGFRHIDSAHLYNNEEQV 61
Query: 295 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 474
G A++ K+ +G V+REDIF T+KLW+T HR V A+ +SLKK LDY+DLYL+H P+
Sbjct: 62 GLAIRSKIADGSVEREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMS 121
Query: 475 L--NADYSHSD---------VDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG 618
L + S +D VD TW +E + G+ K IG+SNFN++QLE +L K G
Sbjct: 122 LKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEIILNKPG 181
Query: 619 -TIKPDAIQIEVH 654
KP Q+E H
Sbjct: 182 LKYKPVCNQVECH 194
>M86609-1|AAB02880.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 142 bits (345), Expect = 7e-34
Identities = 79/193 (40%), Positives = 112/193 (58%), Gaps = 13/193 (6%)
Frame = +1
Query: 115 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 294
+K+N+G MP +G GTY + V KSK + + AI+ G+RH D+A +Y E+++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAE---VPKSKALEATKL---AIEAGFRHIDSAHLYNNEEQV 61
Query: 295 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 474
G A++ K+ +G VKREDIF T+KLW HR V A+ SLK L LDY+DLYL+H+P+
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 475 L-----------NADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG 618
+ N VD TW +E + G+ K IG+SNFN++QLE +L K G
Sbjct: 122 VKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPG 181
Query: 619 -TIKPDAIQIEVH 654
KP Q+E H
Sbjct: 182 LKYKPVCNQVECH 194
>BT007197-1|AAP35861.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 142 bits (345), Expect = 7e-34
Identities = 79/193 (40%), Positives = 112/193 (58%), Gaps = 13/193 (6%)
Frame = +1
Query: 115 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 294
+K+N+G MP +G GTY + V KSK + + AI+ G+RH D+A +Y E+++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAE---VPKSKALEATKL---AIEAGFRHIDSAHLYNNEEQV 61
Query: 295 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 474
G A++ K+ +G VKREDIF T+KLW HR V A+ SLK L LDY+DLYL+H+P+
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 475 L-----------NADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG 618
+ N VD TW +E + G+ K IG+SNFN++QLE +L K G
Sbjct: 122 VKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPG 181
Query: 619 -TIKPDAIQIEVH 654
KP Q+E H
Sbjct: 182 LKYKPVCNQVECH 194
>BC040210-1|AAH40210.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 142 bits (345), Expect = 7e-34
Identities = 79/193 (40%), Positives = 112/193 (58%), Gaps = 13/193 (6%)
Frame = +1
Query: 115 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 294
+K+N+G MP +G GTY + V KSK + + AI+ G+RH D+A +Y E+++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAE---VPKSKALEATKL---AIEAGFRHIDSAHLYNNEEQV 61
Query: 295 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 474
G A++ K+ +G VKREDIF T+KLW HR V A+ SLK L LDY+DLYL+H+P+
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 475 L-----------NADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG 618
+ N VD TW +E + G+ K IG+SNFN++QLE +L K G
Sbjct: 122 VKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPG 181
Query: 619 -TIKPDAIQIEVH 654
KP Q+E H
Sbjct: 182 LKYKPVCNQVECH 194
>BC020216-1|AAH20216.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 142 bits (345), Expect = 7e-34
Identities = 79/193 (40%), Positives = 112/193 (58%), Gaps = 13/193 (6%)
Frame = +1
Query: 115 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 294
+K+N+G MP +G GTY + V KSK + + AI+ G+RH D+A +Y E+++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAE---VPKSKALEATKL---AIEAGFRHIDSAHLYNNEEQV 61
Query: 295 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 474
G A++ K+ +G VKREDIF T+KLW HR V A+ SLK L LDY+DLYL+H+P+
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 475 L-----------NADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG 618
+ N VD TW +E + G+ K IG+SNFN++QLE +L K G
Sbjct: 122 VKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPG 181
Query: 619 -TIKPDAIQIEVH 654
KP Q+E H
Sbjct: 182 LKYKPVCNQVECH 194
>BC015490-1|AAH15490.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 142 bits (345), Expect = 7e-34
Identities = 79/193 (40%), Positives = 112/193 (58%), Gaps = 13/193 (6%)
Frame = +1
Query: 115 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 294
+K+N+G MP +G GTY + V KSK + + AI+ G+RH D+A +Y E+++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAE---VPKSKALEATKL---AIEAGFRHIDSAHLYNNEEQV 61
Query: 295 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 474
G A++ K+ +G VKREDIF T+KLW HR V A+ SLK L LDY+DLYL+H+P+
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 475 L-----------NADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG 618
+ N VD TW +E + G+ K IG+SNFN++QLE +L K G
Sbjct: 122 VKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPG 181
Query: 619 -TIKPDAIQIEVH 654
KP Q+E H
Sbjct: 182 LKYKPVCNQVECH 194
>AL713867-2|CAI16409.1| 323|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 323
Score = 142 bits (345), Expect = 7e-34
Identities = 79/193 (40%), Positives = 112/193 (58%), Gaps = 13/193 (6%)
Frame = +1
Query: 115 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 294
+K+N+G MP +G GTY + V KSK + + AI+ G+RH D+A +Y E+++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAE---VPKSKALEATKL---AIEAGFRHIDSAHLYNNEEQV 61
Query: 295 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 474
G A++ K+ +G VKREDIF T+KLW HR V A+ SLK L LDY+DLYL+H+P+
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 475 L-----------NADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG 618
+ N VD TW +E + G+ K IG+SNFN++QLE +L K G
Sbjct: 122 VKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPG 181
Query: 619 -TIKPDAIQIEVH 654
KP Q+E H
Sbjct: 182 LKYKPVCNQVECH 194
>AB209017-1|BAD92254.1| 286|Homo sapiens aldo-keto reductase family
1, member C2 variant protein.
Length = 286
Score = 142 bits (345), Expect = 7e-34
Identities = 83/209 (39%), Positives = 117/209 (55%), Gaps = 13/209 (6%)
Frame = +1
Query: 67 LVENLTELASTMEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG 246
L +TE+ S + +K+N+G MP +G GTY + V KSK + V AI+ G
Sbjct: 7 LTRPVTEMDSKYQC--VKLNDGHFMPVLGFGTYAPAE---VPKSK---ALEAVKLAIEAG 58
Query: 247 YRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKK 426
+ H D+A VY E+++G A++ K+ +G VKREDIF T+KLW+ HR V A+ SLK
Sbjct: 59 FHHIDSAHVYNNEEQVGLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKN 118
Query: 427 LGLDYIDLYLMHWPIGL-----------NADYSHSDVDFMETWRGLEDAQRMGIVKGIGL 573
L LDY+DLYL+H+P+ + N VD TW +E + G+ K IG+
Sbjct: 119 LQLDYVDLYLIHFPVSVKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGV 178
Query: 574 SNFNKQQLERVL-KEG-TIKPDAIQIEVH 654
SNFN + LE +L K G KP Q+E H
Sbjct: 179 SNFNHRLLEMILNKPGLKYKPVCNQVECH 207
>AB032150-1|BAA92886.1| 323|Homo sapiens 20 alph-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 142 bits (345), Expect = 7e-34
Identities = 79/193 (40%), Positives = 112/193 (58%), Gaps = 13/193 (6%)
Frame = +1
Query: 115 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 294
+K+N+G MP +G GTY + V KSK + + AI+ G+RH D+A +Y E+++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAE---VPKSKALEATKL---AIEAGFRHIDSAHLYNNEEQV 61
Query: 295 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 474
G A++ K+ +G VKREDIF T+KLW HR V A+ SLK L LDY+DLYL+H+P+
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 475 L-----------NADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG 618
+ N VD TW +E + G+ K IG+SNFN++QLE +L K G
Sbjct: 122 VKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPG 181
Query: 619 -TIKPDAIQIEVH 654
KP Q+E H
Sbjct: 182 LKYKPVCNQVECH 194
>AB031083-1|BAA92883.1| 323|Homo sapiens 20 alpha-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 142 bits (345), Expect = 7e-34
Identities = 79/193 (40%), Positives = 112/193 (58%), Gaps = 13/193 (6%)
Frame = +1
Query: 115 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 294
+K+N+G MP +G GTY + V KSK + + AI+ G+RH D+A +Y E+++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAE---VPKSKALEATKL---AIEAGFRHIDSAHLYNNEEQV 61
Query: 295 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 474
G A++ K+ +G VKREDIF T+KLW HR V A+ SLK L LDY+DLYL+H+P+
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 475 L-----------NADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG 618
+ N VD TW +E + G+ K IG+SNFN++QLE +L K G
Sbjct: 122 VKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPG 181
Query: 619 -TIKPDAIQIEVH 654
KP Q+E H
Sbjct: 182 LKYKPVCNQVECH 194
>DQ269985-1|ABB76132.1| 323|Homo sapiens type II 3a-hydroxysteroid
dehydrogenase variant protein.
Length = 323
Score = 142 bits (344), Expect = 1e-33
Identities = 82/193 (42%), Positives = 114/193 (59%), Gaps = 13/193 (6%)
Frame = +1
Query: 115 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 294
+K+N+G MP +G GTY + V KSK + + AI+ G+RH D+A +Y E+++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAE---VPKSKALEATKL---AIEAGFRHIDSAHLYNNEEQV 61
Query: 295 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 474
G AV+ K+ +G VKREDIF T+KLW HR V A+ SLKK LDY+DLYL+H P+
Sbjct: 62 GLAVRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKKAQLDYVDLYLIHSPMS 121
Query: 475 L--NADYSHSD---------VDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG 618
L + S +D VD TW +E + G+ K IG+SNFN++QLE +L K G
Sbjct: 122 LKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPG 181
Query: 619 -TIKPDAIQIEVH 654
KP Q+E H
Sbjct: 182 LKYKPVCNQVECH 194
>L43839-1|AAB41916.1| 323|Homo sapiens 3-alpha-hydroxysteroid
dehydrogenase protein.
Length = 323
Score = 142 bits (343), Expect = 1e-33
Identities = 81/193 (41%), Positives = 116/193 (60%), Gaps = 13/193 (6%)
Frame = +1
Query: 115 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 294
+K+N+G MP +G GTY + V +SK +V AI+ G+RH D+A +Y E+++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPPE---VPRSK---ALEVTKLAIEAGFRHIDSAHLYNNEEQV 61
Query: 295 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 474
G A++ K+ +G V REDIF T+KLW+T HR V A+ +SLKK LDY+DLYL+H P+
Sbjct: 62 GLAIRSKIADGSVMREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMS 121
Query: 475 L--NADYSHSD---------VDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG 618
L + S +D VD TW +E + G+ K IG+SNFN++QLE +L K G
Sbjct: 122 LKPGEELSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEIILNKPG 181
Query: 619 -TIKPDAIQIEVH 654
KP Q+E H
Sbjct: 182 LKYKPVCNQVECH 194
>U05598-1|AAA20937.1| 323|Homo sapiens dihydrodiol dehydrogenase
protein.
Length = 323
Score = 141 bits (342), Expect = 2e-33
Identities = 79/193 (40%), Positives = 110/193 (56%), Gaps = 13/193 (6%)
Frame = +1
Query: 115 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 294
+K+N+G MP +G GTY + V KSK + V AI+ G+ H D+A VY E+++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAE---VPKSK---ALEAVKLAIEAGFHHIDSAHVYNNEEQV 61
Query: 295 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 474
G A++ K+ +G VKREDIF T+KLW+ HR V A+ SLK L LDY+DLYL+H+P+
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 475 L-----------NADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG 618
+ N VD TW +E + G+ K IG+SNFN + LE +L K G
Sbjct: 122 VKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPG 181
Query: 619 -TIKPDAIQIEVH 654
KP Q+E H
Sbjct: 182 LKYKPVCNQVECH 194
>BT006653-1|AAP35299.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 141 bits (342), Expect = 2e-33
Identities = 79/193 (40%), Positives = 110/193 (56%), Gaps = 13/193 (6%)
Frame = +1
Query: 115 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 294
+K+N+G MP +G GTY + V KSK + V AI+ G+ H D+A VY E+++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAE---VPKSK---ALEAVKLAIEAGFHHIDSAHVYNNEEQV 61
Query: 295 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 474
G A++ K+ +G VKREDIF T+KLW+ HR V A+ SLK L LDY+DLYL+H+P+
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 475 L-----------NADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG 618
+ N VD TW +E + G+ K IG+SNFN + LE +L K G
Sbjct: 122 VKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPG 181
Query: 619 -TIKPDAIQIEVH 654
KP Q+E H
Sbjct: 182 LKYKPVCNQVECH 194
>BC063574-1|AAH63574.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 141 bits (342), Expect = 2e-33
Identities = 79/193 (40%), Positives = 110/193 (56%), Gaps = 13/193 (6%)
Frame = +1
Query: 115 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 294
+K+N+G MP +G GTY + V KSK + V AI+ G+ H D+A VY E+++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAE---VPKSK---ALEAVKLAIEAGFHHIDSAHVYNNEEQV 61
Query: 295 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 474
G A++ K+ +G VKREDIF T+KLW+ HR V A+ SLK L LDY+DLYL+H+P+
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 475 L-----------NADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG 618
+ N VD TW +E + G+ K IG+SNFN + LE +L K G
Sbjct: 122 VKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPG 181
Query: 619 -TIKPDAIQIEVH 654
KP Q+E H
Sbjct: 182 LKYKPVCNQVECH 194
>BC007024-1|AAH07024.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 141 bits (342), Expect = 2e-33
Identities = 79/193 (40%), Positives = 110/193 (56%), Gaps = 13/193 (6%)
Frame = +1
Query: 115 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 294
+K+N+G MP +G GTY + V KSK + V AI+ G+ H D+A VY E+++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAE---VPKSK---ALEAVKLAIEAGFHHIDSAHVYNNEEQV 61
Query: 295 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 474
G A++ K+ +G VKREDIF T+KLW+ HR V A+ SLK L LDY+DLYL+H+P+
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 475 L-----------NADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG 618
+ N VD TW +E + G+ K IG+SNFN + LE +L K G
Sbjct: 122 VKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPG 181
Query: 619 -TIKPDAIQIEVH 654
KP Q+E H
Sbjct: 182 LKYKPVCNQVECH 194
>AL713867-1|CAI16408.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 141 bits (342), Expect = 2e-33
Identities = 79/193 (40%), Positives = 110/193 (56%), Gaps = 13/193 (6%)
Frame = +1
Query: 115 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 294
+K+N+G MP +G GTY + V KSK + V AI+ G+ H D+A VY E+++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAE---VPKSK---ALEAVKLAIEAGFHHIDSAHVYNNEEQV 61
Query: 295 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 474
G A++ K+ +G VKREDIF T+KLW+ HR V A+ SLK L LDY+DLYL+H+P+
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 475 L-----------NADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG 618
+ N VD TW +E + G+ K IG+SNFN + LE +L K G
Sbjct: 122 VKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPG 181
Query: 619 -TIKPDAIQIEVH 654
KP Q+E H
Sbjct: 182 LKYKPVCNQVECH 194
>AL391427-1|CAI14726.1| 323|Homo sapiens aldo-keto reductase family
1, member C2 (dihydrodiol dehydrogenase 2; bile acid
protein.
Length = 323
Score = 141 bits (342), Expect = 2e-33
Identities = 79/193 (40%), Positives = 110/193 (56%), Gaps = 13/193 (6%)
Frame = +1
Query: 115 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 294
+K+N+G MP +G GTY + V KSK + V AI+ G+ H D+A VY E+++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAE---VPKSK---ALEAVKLAIEAGFHHIDSAHVYNNEEQV 61
Query: 295 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 474
G A++ K+ +G VKREDIF T+KLW+ HR V A+ SLK L LDY+DLYL+H+P+
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 475 L-----------NADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG 618
+ N VD TW +E + G+ K IG+SNFN + LE +L K G
Sbjct: 122 VKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPG 181
Query: 619 -TIKPDAIQIEVH 654
KP Q+E H
Sbjct: 182 LKYKPVCNQVECH 194
>AB032153-1|BAA92891.1| 323|Homo sapiens bile acid-binding protein
protein.
Length = 323
Score = 141 bits (342), Expect = 2e-33
Identities = 79/193 (40%), Positives = 110/193 (56%), Gaps = 13/193 (6%)
Frame = +1
Query: 115 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 294
+K+N+G MP +G GTY + V KSK + V AI+ G+ H D+A VY E+++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAE---VPKSK---ALEAVKLAIEAGFHHIDSAHVYNNEEQV 61
Query: 295 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 474
G A++ K+ +G VKREDIF T+KLW+ HR V A+ SLK L LDY+DLYL+H+P+
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 475 L-----------NADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG 618
+ N VD TW +E + G+ K IG+SNFN + LE +L K G
Sbjct: 122 VKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPG 181
Query: 619 -TIKPDAIQIEVH 654
KP Q+E H
Sbjct: 182 LKYKPVCNQVECH 194
>AB031084-1|BAA92884.1| 323|Homo sapiens bile acid-binding protein
protein.
Length = 323
Score = 141 bits (342), Expect = 2e-33
Identities = 79/193 (40%), Positives = 110/193 (56%), Gaps = 13/193 (6%)
Frame = +1
Query: 115 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 294
+K+N+G MP +G GTY + V KSK + V AI+ G+ H D+A VY E+++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAE---VPKSK---ALEAVKLAIEAGFHHIDSAHVYNNEEQV 61
Query: 295 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 474
G A++ K+ +G VKREDIF T+KLW+ HR V A+ SLK L LDY+DLYL+H+P+
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 475 L-----------NADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG 618
+ N VD TW +E + G+ K IG+SNFN + LE +L K G
Sbjct: 122 VKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPG 181
Query: 619 -TIKPDAIQIEVH 654
KP Q+E H
Sbjct: 182 LKYKPVCNQVECH 194
>AB021654-1|BAA36169.1| 323|Homo sapiens DD2/bile acid-binding
protein/AKR1C2/3alpha-hydroxysteroid dehydrogenase type
3 protein.
Length = 323
Score = 141 bits (342), Expect = 2e-33
Identities = 79/193 (40%), Positives = 110/193 (56%), Gaps = 13/193 (6%)
Frame = +1
Query: 115 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 294
+K+N+G MP +G GTY + V KSK + V AI+ G+ H D+A VY E+++
Sbjct: 8 VKLNDGHFMPVLGFGTYAPAE---VPKSK---ALEAVKLAIEAGFHHIDSAHVYNNEEQV 61
Query: 295 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 474
G A++ K+ +G VKREDIF T+KLW+ HR V A+ SLK L LDY+DLYL+H+P+
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVS 121
Query: 475 L-----------NADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG 618
+ N VD TW +E + G+ K IG+SNFN + LE +L K G
Sbjct: 122 VKPGEEVIPKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPG 181
Query: 619 -TIKPDAIQIEVH 654
KP Q+E H
Sbjct: 182 LKYKPVCNQVECH 194
>S68290-1|AAD14012.1| 320|Homo sapiens chlordecone reductase
homolog protein.
Length = 320
Score = 135 bits (327), Expect = 1e-31
Identities = 76/193 (39%), Positives = 109/193 (56%), Gaps = 13/193 (6%)
Frame = +1
Query: 115 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 294
+K+N+G MP +G GTY + V KSK + + AI+ G+RH D+A +Y E+++
Sbjct: 5 VKLNDGHFMPVLGFGTYAPAE---VPKSKALEATKL---AIEAGFRHIDSAHLYNNEEQV 58
Query: 295 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 474
G A++ K+ +G VKREDIF T+KLW HR A+ SLK L LDY+DLYL+H+P+
Sbjct: 59 GLAIRSKIADGSVKREDIFYTSKLWCNSHRPELDRPALERSLKNLQLDYVDLYLIHFPVS 118
Query: 475 L-----------NADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG 618
+ N VD TW +E + + K IG+SNFN+ LE +L K G
Sbjct: 119 VKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAELAKSIGVSNFNRSTLEMILNKPG 178
Query: 619 -TIKPDAIQIEVH 654
+KP Q+E H
Sbjct: 179 LQVKPVCNQVECH 191
>BC020744-1|AAH20744.1| 323|Homo sapiens aldo-keto reductase family
1, member C4 (chlordecone reductase; 3-alpha hydroxy
protein.
Length = 323
Score = 134 bits (325), Expect = 2e-31
Identities = 77/193 (39%), Positives = 112/193 (58%), Gaps = 13/193 (6%)
Frame = +1
Query: 115 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 294
+++N+G MP +G GTY + V +++ + V AI+ G+RH D+A +Y E+++
Sbjct: 8 VELNDGHFMPVLGFGTYAPPE---VPRNRAVE---VTKLAIEAGFRHIDSAYLYNNEEQV 61
Query: 295 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 474
G A++ K+ +G VKREDIF T+KLW T + V A+ SLKKL LDY+DLYL+H+P+
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMA 121
Query: 475 L-----------NADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG 618
L N VD TW +E + G+ K IG+SNFN +QLE +L K G
Sbjct: 122 LKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNYRQLEMILNKPG 181
Query: 619 -TIKPDAIQIEVH 654
KP Q+E H
Sbjct: 182 LKYKPVCNQVECH 194
>S68287-1|AAD14010.1| 323|Homo sapiens chlordecone reductase
protein.
Length = 323
Score = 134 bits (324), Expect = 3e-31
Identities = 77/193 (39%), Positives = 112/193 (58%), Gaps = 13/193 (6%)
Frame = +1
Query: 115 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 294
+++N+G MP +G GTY + V +++ + V AI+ G+RH D+A +Y E+++
Sbjct: 8 VELNDGHFMPVLGFGTYAPPE---VPRNRAVE---VTKLAIEAGFRHIDSAYLYNNEEQV 61
Query: 295 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 474
G A++ K+ +G VKREDIF T+KLW T + V A+ SLKKL LDY+DLYL+H+P+
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMA 121
Query: 475 L-----------NADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG 618
L N VD TW +E + G+ K IG+SNFN +QLE +L K G
Sbjct: 122 LKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPG 181
Query: 619 -TIKPDAIQIEVH 654
KP Q+E H
Sbjct: 182 LKYKPVCNQVECH 194
>D26125-1|BAA05122.1| 321|Homo sapiens 3
alpha-hydroxysteroid/dihydrodiol dehydrogenase DD4
protein.
Length = 321
Score = 134 bits (324), Expect = 3e-31
Identities = 77/193 (39%), Positives = 112/193 (58%), Gaps = 13/193 (6%)
Frame = +1
Query: 115 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 294
+++N+G MP +G GTY + V +++ + V AI+ G+RH D+A +Y E+++
Sbjct: 6 VELNDGHFMPVLGFGTYAPPE---VPRNRAVE---VTKLAIEAGFRHIDSAYLYNNEEQV 59
Query: 295 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 474
G A++ K+ +G VKREDIF T+KLW T + V A+ SLKKL LDY+DLYL+H+P+
Sbjct: 60 GLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMA 119
Query: 475 L-----------NADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG 618
L N VD TW +E + G+ K IG+SNFN +QLE +L K G
Sbjct: 120 LKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPG 179
Query: 619 -TIKPDAIQIEVH 654
KP Q+E H
Sbjct: 180 LKYKPVCNQVECH 192
>AL355303-2|CAI14202.1| 323|Homo sapiens aldo-keto reductase family
1, member C4 (chlordecone reductase; 3-alpha hydroxy
protein.
Length = 323
Score = 134 bits (324), Expect = 3e-31
Identities = 77/193 (39%), Positives = 112/193 (58%), Gaps = 13/193 (6%)
Frame = +1
Query: 115 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 294
+++N+G MP +G GTY + V +++ + V AI+ G+RH D+A +Y E+++
Sbjct: 8 VELNDGHFMPVLGFGTYAPPE---VPRNRAVE---VTKLAIEAGFRHIDSAYLYNNEEQV 61
Query: 295 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 474
G A++ K+ +G VKREDIF T+KLW T + V A+ SLKKL LDY+DLYL+H+P+
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMA 121
Query: 475 L-----------NADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG 618
L N VD TW +E + G+ K IG+SNFN +QLE +L K G
Sbjct: 122 LKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPG 181
Query: 619 -TIKPDAIQIEVH 654
KP Q+E H
Sbjct: 182 LKYKPVCNQVECH 194
>AB045829-1|BAA99542.1| 323|Homo sapiens 3alpha-hydroxysteroid
dehydrogenase variant protein.
Length = 323
Score = 134 bits (324), Expect = 3e-31
Identities = 77/193 (39%), Positives = 112/193 (58%), Gaps = 13/193 (6%)
Frame = +1
Query: 115 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 294
+++N+G MP +G GTY + V +++ + V AI+ G+RH D+A +Y E+++
Sbjct: 8 VELNDGHFMPVLGFGTYAPPE---VPRNRAVE---VTKLAIEAGFRHIDSAYLYNNEEQV 61
Query: 295 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 474
G A++ K+ +G VKREDIF T+KLW T + V A+ SLKKL LDY+DLYL+H+P+
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMA 121
Query: 475 L-----------NADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG 618
L N VD TW +E + G+ K IG+SNFN +QLE +L K G
Sbjct: 122 LKPGETPLPKDENGKVIFDTVDLCATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPG 181
Query: 619 -TIKPDAIQIEVH 654
KP Q+E H
Sbjct: 182 LKYKPVCNQVECH 194
>AB032163-1|BAA92893.1| 323|Homo sapiens dihydrodiol dehydrogenase
4 protein.
Length = 323
Score = 134 bits (324), Expect = 3e-31
Identities = 77/193 (39%), Positives = 112/193 (58%), Gaps = 13/193 (6%)
Frame = +1
Query: 115 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 294
+++N+G MP +G GTY + V +++ + V AI+ G+RH D+A +Y E+++
Sbjct: 8 VELNDGHFMPVLGFGTYAPPE---VPRNRAVE---VTKLAIEAGFRHIDSAYLYNNEEQV 61
Query: 295 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 474
G A++ K+ +G VKREDIF T+KLW T + V A+ SLKKL LDY+DLYL+H+P+
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMA 121
Query: 475 L-----------NADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG 618
L N VD TW +E + G+ K IG+SNFN +QLE +L K G
Sbjct: 122 LKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPG 181
Query: 619 -TIKPDAIQIEVH 654
KP Q+E H
Sbjct: 182 LKYKPVCNQVECH 194
>AB031085-1|BAA92885.1| 323|Homo sapiens dihydrodiol dehydrogenase
4 protein.
Length = 323
Score = 134 bits (324), Expect = 3e-31
Identities = 77/193 (39%), Positives = 112/193 (58%), Gaps = 13/193 (6%)
Frame = +1
Query: 115 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 294
+++N+G MP +G GTY + V +++ + V AI+ G+RH D+A +Y E+++
Sbjct: 8 VELNDGHFMPVLGFGTYAPPE---VPRNRAVE---VTKLAIEAGFRHIDSAYLYNNEEQV 61
Query: 295 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 474
G A++ K+ +G VKREDIF T+KLW T + V A+ SLKKL LDY+DLYL+H+P+
Sbjct: 62 GLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMA 121
Query: 475 L-----------NADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG 618
L N VD TW +E + G+ K IG+SNFN +QLE +L K G
Sbjct: 122 LKPGETPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPG 181
Query: 619 -TIKPDAIQIEVH 654
KP Q+E H
Sbjct: 182 LKYKPVCNQVECH 194
>U37100-1|AAC17469.1| 316|Homo sapiens aldose reductase-like
peptide protein.
Length = 316
Score = 132 bits (319), Expect = 1e-30
Identities = 75/193 (38%), Positives = 111/193 (57%), Gaps = 13/193 (6%)
Frame = +1
Query: 115 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 294
++++ MP +GLGT+ KS ++++ V AID GYRH D A VY+ E E+
Sbjct: 5 VELSTKAKMPIVGLGTW---------KSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEV 55
Query: 295 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 474
GEA++ K++E VKRED+FI +KLW T R V +A +LK L L Y+D+YL+HWP G
Sbjct: 56 GEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQG 115
Query: 475 LNA--DYSHSD---------VDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG 618
+ D D F++ W +E+ G+VK +G+SNF+ Q+E++L K G
Sbjct: 116 FKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPG 175
Query: 619 -TIKPDAIQIEVH 654
KP Q+E H
Sbjct: 176 LKYKPVTNQVECH 188
>CR541801-1|CAG46600.1| 316|Homo sapiens AKR1B10 protein.
Length = 316
Score = 132 bits (319), Expect = 1e-30
Identities = 75/193 (38%), Positives = 111/193 (57%), Gaps = 13/193 (6%)
Frame = +1
Query: 115 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 294
++++ MP +GLGT+ KS ++++ V AID GYRH D A VY+ E E+
Sbjct: 5 VELSTKAKMPIVGLGTW---------KSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEV 55
Query: 295 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 474
GEA++ K++E VKRED+FI +KLW T R V +A +LK L L Y+D+YL+HWP G
Sbjct: 56 GEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQG 115
Query: 475 LNA--DYSHSD---------VDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG 618
+ D D F++ W +E+ G+VK +G+SNF+ Q+E++L K G
Sbjct: 116 FKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPG 175
Query: 619 -TIKPDAIQIEVH 654
KP Q+E H
Sbjct: 176 LKYKPVTNQVECH 188
>BT006794-1|AAP35440.1| 316|Homo sapiens aldo-keto reductase family
1, member B10 (aldose reductase) protein.
Length = 316
Score = 132 bits (319), Expect = 1e-30
Identities = 75/193 (38%), Positives = 111/193 (57%), Gaps = 13/193 (6%)
Frame = +1
Query: 115 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 294
++++ MP +GLGT+ KS ++++ V AID GYRH D A VY+ E E+
Sbjct: 5 VELSTKAKMPIVGLGTW---------KSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEV 55
Query: 295 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 474
GEA++ K++E VKRED+FI +KLW T R V +A +LK L L Y+D+YL+HWP G
Sbjct: 56 GEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQG 115
Query: 475 LNA--DYSHSD---------VDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG 618
+ D D F++ W +E+ G+VK +G+SNF+ Q+E++L K G
Sbjct: 116 FKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPG 175
Query: 619 -TIKPDAIQIEVH 654
KP Q+E H
Sbjct: 176 LKYKPVTNQVECH 188
>BC008837-1|AAH08837.1| 316|Homo sapiens aldo-keto reductase family
1, member B10 (aldose reductase) protein.
Length = 316
Score = 132 bits (319), Expect = 1e-30
Identities = 75/193 (38%), Positives = 111/193 (57%), Gaps = 13/193 (6%)
Frame = +1
Query: 115 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 294
++++ MP +GLGT+ KS ++++ V AID GYRH D A VY+ E E+
Sbjct: 5 VELSTKAKMPIVGLGTW---------KSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEV 55
Query: 295 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 474
GEA++ K++E VKRED+FI +KLW T R V +A +LK L L Y+D+YL+HWP G
Sbjct: 56 GEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQG 115
Query: 475 LNA--DYSHSD---------VDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG 618
+ D D F++ W +E+ G+VK +G+SNF+ Q+E++L K G
Sbjct: 116 FKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPG 175
Query: 619 -TIKPDAIQIEVH 654
KP Q+E H
Sbjct: 176 LKYKPVTNQVECH 188
>AF052577-1|AAC36465.1| 316|Homo sapiens aldo-keto reductase
protein.
Length = 316
Score = 132 bits (319), Expect = 1e-30
Identities = 75/193 (38%), Positives = 111/193 (57%), Gaps = 13/193 (6%)
Frame = +1
Query: 115 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 294
++++ MP +GLGT+ KS ++++ V AID GYRH D A VY+ E E+
Sbjct: 5 VELSTKAKMPIVGLGTW---------KSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEV 55
Query: 295 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 474
GEA++ K++E VKRED+FI +KLW T R V +A +LK L L Y+D+YL+HWP G
Sbjct: 56 GEAIQEKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQG 115
Query: 475 LNA--DYSHSD---------VDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG 618
+ D D F++ W +E+ G+VK +G+SNF+ Q+E++L K G
Sbjct: 116 FKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPG 175
Query: 619 -TIKPDAIQIEVH 654
KP Q+E H
Sbjct: 176 LKYKPVTNQVECH 188
>D26124-1|BAA05121.1| 306|Homo sapiens dihydrodiol dehydrogenase
isoform DD1 protein.
Length = 306
Score = 130 bits (315), Expect = 3e-30
Identities = 74/182 (40%), Positives = 104/182 (57%), Gaps = 13/182 (7%)
Frame = +1
Query: 148 IGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEG 327
+G GTY + V KSK + + AI+ G+RH D+A +Y E+++G A++ K+ +G
Sbjct: 2 LGFGTYAPAE---VPKSKALEATKL---AIEAGFRHIDSAHLYNNEEQVGLAIRSKIADG 55
Query: 328 VVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL---------- 477
VKREDIF T+KLW HR V A+ SLK L LDY+DLYL+H+P+ +
Sbjct: 56 SVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPKD 115
Query: 478 -NADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAIQIE 648
N VD TW +E + G+ K IG+SNFN++QLE +L K G KP Q+E
Sbjct: 116 ENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVE 175
Query: 649 VH 654
H
Sbjct: 176 CH 177
>AF524864-1|AAO13380.1| 316|Homo sapiens aldo-ketoreductase
protein.
Length = 316
Score = 129 bits (312), Expect = 7e-30
Identities = 74/193 (38%), Positives = 110/193 (56%), Gaps = 13/193 (6%)
Frame = +1
Query: 115 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 294
++++ MP +GLGT+ KS ++++ V AID GYRH D A VY+ E E+
Sbjct: 5 VELSTKAKMPIVGLGTW---------KSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEV 55
Query: 295 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 474
GEA++ K++E VKRED+FI +KLW T R V +A +LK L Y+D+YL+HWP G
Sbjct: 56 GEAIQEKIQEKAVKREDLFIASKLWPTFFERPLVRKAFEKTLKDPKLSYLDVYLIHWPQG 115
Query: 475 LNA--DYSHSD---------VDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG 618
+ D D F++ W +E+ G+VK +G+SNF+ Q+E++L K G
Sbjct: 116 FKSGDDLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPG 175
Query: 619 -TIKPDAIQIEVH 654
KP Q+E H
Sbjct: 176 LKYKPVTNQVECH 188
>M33375-1|AAA35658.1| 308|Homo sapiens protein ( Human chlordecone
reductase mRNA, complete cds. ).
Length = 308
Score = 128 bits (310), Expect = 1e-29
Identities = 75/185 (40%), Positives = 106/185 (57%), Gaps = 13/185 (7%)
Frame = +1
Query: 139 MPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKV 318
MP +G GTY + V +++ + V AI+ G+RH D+A +Y E+++G A++ K+
Sbjct: 1 MPVLGFGTYAPPE---VPRNRAVE---VTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSKI 54
Query: 319 EEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL------- 477
+G VKREDIF T+KLW T + V A+ SLKKL LDY+DLYL+H+P+ L
Sbjct: 55 ADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGETPL 114
Query: 478 ----NADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-KEG-TIKPDAI 639
N VD TW +E + G+ K IG+SNFN +QLE +L K G KP
Sbjct: 115 PKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCN 174
Query: 640 QIEVH 654
Q+E H
Sbjct: 175 QVECH 179
>Z28339-1|CAA82193.1| 326|Homo sapiens delta 4-3-oxosteroid 5
beta-reductase protein.
Length = 326
Score = 126 bits (303), Expect = 9e-29
Identities = 72/194 (37%), Positives = 106/194 (54%), Gaps = 14/194 (7%)
Frame = +1
Query: 115 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDK-QLRDVVMRAIDVGYRHFDTASVYETEQE 291
+ +++G +P IGLGTY KS K V AID GYRH D A +Y+ E E
Sbjct: 10 IPLSDGNSIPIIGLGTY------SEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHE 63
Query: 292 IGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 471
+GEA++ K+ EG V+REDIF KLW T H V + +L+ L LDY+DLY++ P+
Sbjct: 64 VGEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPM 123
Query: 472 GL-----------NADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEG 618
N + + + TW +E + G+VK +G+SNFN++QLE +L +
Sbjct: 124 AFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKP 183
Query: 619 TI--KPDAIQIEVH 654
+ KP + Q+E H
Sbjct: 184 GLKHKPVSNQVECH 197
>BC130627-1|AAI30628.1| 326|Homo sapiens aldo-keto reductase family
1, member D1 (delta 4-3-ketosteroid-5-beta-reductase
protein.
Length = 326
Score = 126 bits (303), Expect = 9e-29
Identities = 72/194 (37%), Positives = 106/194 (54%), Gaps = 14/194 (7%)
Frame = +1
Query: 115 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDK-QLRDVVMRAIDVGYRHFDTASVYETEQE 291
+ +++G +P IGLGTY KS K V AID GYRH D A +Y+ E E
Sbjct: 10 IPLSDGNSIPIIGLGTY------SEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHE 63
Query: 292 IGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 471
+GEA++ K+ EG V+REDIF KLW T H V + +L+ L LDY+DLY++ P+
Sbjct: 64 VGEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPM 123
Query: 472 GL-----------NADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEG 618
N + + + TW +E + G+VK +G+SNFN++QLE +L +
Sbjct: 124 AFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKP 183
Query: 619 TI--KPDAIQIEVH 654
+ KP + Q+E H
Sbjct: 184 GLKHKPVSNQVECH 197
>BC130625-1|AAI30626.1| 326|Homo sapiens aldo-keto reductase family
1, member D1 (delta 4-3-ketosteroid-5-beta-reductase
protein.
Length = 326
Score = 126 bits (303), Expect = 9e-29
Identities = 72/194 (37%), Positives = 106/194 (54%), Gaps = 14/194 (7%)
Frame = +1
Query: 115 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDK-QLRDVVMRAIDVGYRHFDTASVYETEQE 291
+ +++G +P IGLGTY KS K V AID GYRH D A +Y+ E E
Sbjct: 10 IPLSDGNSIPIIGLGTY------SEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHE 63
Query: 292 IGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 471
+GEA++ K+ EG V+REDIF KLW T H V + +L+ L LDY+DLY++ P+
Sbjct: 64 VGEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPM 123
Query: 472 GL-----------NADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEG 618
N + + + TW +E + G+VK +G+SNFN++QLE +L +
Sbjct: 124 AFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKP 183
Query: 619 TI--KPDAIQIEVH 654
+ KP + Q+E H
Sbjct: 184 GLKHKPVSNQVECH 197
>AF283659-1|AAG39381.1| 326|Homo sapiens 5-beta steroid reductase
protein.
Length = 326
Score = 126 bits (303), Expect = 9e-29
Identities = 72/194 (37%), Positives = 106/194 (54%), Gaps = 14/194 (7%)
Frame = +1
Query: 115 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDK-QLRDVVMRAIDVGYRHFDTASVYETEQE 291
+ +++G +P IGLGTY KS K V AID GYRH D A +Y+ E E
Sbjct: 10 IPLSDGNSIPIIGLGTY------SEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHE 63
Query: 292 IGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 471
+GEA++ K+ EG V+REDIF KLW T H V + +L+ L LDY+DLY++ P+
Sbjct: 64 VGEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPM 123
Query: 472 GL-----------NADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEG 618
N + + + TW +E + G+VK +G+SNFN++QLE +L +
Sbjct: 124 AFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKP 183
Query: 619 TI--KPDAIQIEVH 654
+ KP + Q+E H
Sbjct: 184 GLKHKPVSNQVECH 197
>AL713867-3|CAI16410.1| 247|Homo sapiens aldo-keto reductase family
1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha
protein.
Length = 247
Score = 107 bits (256), Expect(2) = 2e-25
Identities = 58/135 (42%), Positives = 78/135 (57%), Gaps = 13/135 (9%)
Frame = +1
Query: 289 EIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 468
E+G A++ K+ +G VKREDIF T+KLW HR V A+ SLK L LDY+DLYL+H+P
Sbjct: 26 EVGLAIRSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFP 85
Query: 469 IGL-----------NADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL-K 612
+ + N VD TW +E + G+ K IG+SNFN++QLE +L K
Sbjct: 86 VSVKPGEEVIPKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNK 145
Query: 613 EG-TIKPDAIQIEVH 654
G KP Q+E H
Sbjct: 146 PGLKYKPVCNQVECH 160
Score = 28.7 bits (61), Expect(2) = 2e-25
Identities = 11/29 (37%), Positives = 18/29 (62%)
Frame = +1
Query: 115 LKMNNGRDMPAIGLGTYLGFDQNGVVKSK 201
+K+N+G MP +G GTY + ++SK
Sbjct: 6 VKLNDGHFMPVLGFGTYAPAEVGLAIRSK 34
>AB040822-1|BAC54567.1| 222|Homo sapiens aldo-keto reductase
related protein 3 protein.
Length = 222
Score = 113 bits (273), Expect(2) = 4e-25
Identities = 52/113 (46%), Positives = 75/113 (66%)
Frame = +1
Query: 136 DMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMK 315
D+PA+GL ++ K+ ++ + V AID GYRHFD A Y E+E+G ++ K
Sbjct: 3 DIPAVGLSSW---------KASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCK 53
Query: 316 VEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 474
++EG V+RED+FI TKLW T H+++ V A SLK L L+Y+DLYL+HWP+G
Sbjct: 54 IKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMG 106
Score = 21.0 bits (42), Expect(2) = 4e-25
Identities = 6/9 (66%), Positives = 8/9 (88%)
Frame = +1
Query: 496 SDVDFMETW 522
SD DF++TW
Sbjct: 144 SDTDFLDTW 152
>AL355480-2|CAI22458.1| 147|Homo sapiens aldo-keto reductase family
1, member A1 (aldehydela) protein.
Length = 147
Score = 112 bits (269), Expect = 1e-24
Identities = 63/156 (40%), Positives = 88/156 (56%), Gaps = 12/156 (7%)
Frame = +1
Query: 100 MEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYE 279
M + ++ G+ MP IGLGT+ KS+ Q++ V A+ VGYRH D A++Y
Sbjct: 1 MAASCVLLHTGQKMPLIGLGTW---------KSEPGQVKAAVKYALSVGYRHIDCAAIYG 51
Query: 280 TEQEIGEAVKMKVEEG-VVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYL 456
E EIGEA+K V G V RE++F+T+KLWNT+H +V A+ +L L L+Y+DLYL
Sbjct: 52 NEPEIGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYL 111
Query: 457 MHWPIGL---------NAD--YSHSDVDFMETWRGL 531
MHWP NAD + + ETW+ L
Sbjct: 112 MHWPYAFERGDNPFPKNADGTICYDSTHYKETWKAL 147
>BC101205-1|AAI01206.1| 129|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 129
Score = 107 bits (258), Expect = 3e-23
Identities = 54/122 (44%), Positives = 79/122 (64%)
Frame = +1
Query: 112 SLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 291
S+++N+G MP +G GTY + KS+ + V AIDVG+RH D+A +Y+ E+E
Sbjct: 10 SVRLNDGPFMPVLGFGTYA---PDHTPKSQAAEATKV---AIDVGFRHIDSAYLYQNEEE 63
Query: 292 IGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 471
+G+A+ K+ +G VKRE+IF T KLW T R V A+ SLKKLG DY+DL+++H P
Sbjct: 64 VGQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPF 123
Query: 472 GL 477
+
Sbjct: 124 AM 125
>BC101204-1|AAI01205.1| 129|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 129
Score = 107 bits (258), Expect = 3e-23
Identities = 54/122 (44%), Positives = 79/122 (64%)
Frame = +1
Query: 112 SLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 291
S+++N+G MP +G GTY + KS+ + V AIDVG+RH D+A +Y+ E+E
Sbjct: 10 SVRLNDGPFMPVLGFGTYA---PDHTPKSQAAEATKV---AIDVGFRHIDSAYLYQNEEE 63
Query: 292 IGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 471
+G+A+ K+ +G VKRE+IF T KLW T R V A+ SLKKLG DY+DL+++H P
Sbjct: 64 VGQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPF 123
Query: 472 GL 477
+
Sbjct: 124 AM 125
>AL391427-2|CAI14727.1| 302|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 302
Score = 107 bits (258), Expect = 3e-23
Identities = 54/122 (44%), Positives = 79/122 (64%)
Frame = +1
Query: 112 SLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 291
S+++N+G MP +G GTY + KS+ + V AIDVG+RH D+A +Y+ E+E
Sbjct: 10 SVRLNDGPFMPVLGFGTYA---PDHTPKSQAAEATKV---AIDVGFRHIDSAYLYQNEEE 63
Query: 292 IGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 471
+G+A+ K+ +G VKRE+IF T KLW T R V A+ SLKKLG DY+DL+++H P
Sbjct: 64 VGQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPF 123
Query: 472 GL 477
+
Sbjct: 124 AM 125
>AL355303-1|CAI14201.1| 302|Homo sapiens aldo-keto reductase family
1, member C-like 1 protein.
Length = 302
Score = 107 bits (258), Expect = 3e-23
Identities = 54/122 (44%), Positives = 79/122 (64%)
Frame = +1
Query: 112 SLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 291
S+++N+G MP +G GTY + KS+ + V AIDVG+RH D+A +Y+ E+E
Sbjct: 10 SVRLNDGPFMPVLGFGTYA---PDHTPKSQAAEATKV---AIDVGFRHIDSAYLYQNEEE 63
Query: 292 IGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 471
+G+A+ K+ +G VKRE+IF T KLW T R V A+ SLKKLG DY+DL+++H P
Sbjct: 64 VGQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPF 123
Query: 472 GL 477
+
Sbjct: 124 AM 125
>AK131335-1|BAD18494.1| 129|Homo sapiens protein ( Homo sapiens
cDNA FLJ16347 fis, clone TESTI2036288, moderately
similar to PROSTAGLANDIN-F SYNTHASE 1 (EC 1.1.1.188). ).
Length = 129
Score = 107 bits (258), Expect = 3e-23
Identities = 54/122 (44%), Positives = 79/122 (64%)
Frame = +1
Query: 112 SLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 291
S+++N+G MP +G GTY + KS+ + V AIDVG+RH D+A +Y+ E+E
Sbjct: 10 SVRLNDGPFMPVLGFGTYA---PDHTPKSQAAEATKV---AIDVGFRHIDSAYLYQNEEE 63
Query: 292 IGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 471
+G+A+ K+ +G VKRE+IF T KLW T R V A+ SLKKLG DY+DL+++H P
Sbjct: 64 VGQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPF 123
Query: 472 GL 477
+
Sbjct: 124 AM 125
>AB037902-1|BAA92887.1| 130|Homo sapiens truncated aldo-keto
reductase protein.
Length = 130
Score = 107 bits (256), Expect = 5e-23
Identities = 54/122 (44%), Positives = 76/122 (62%)
Frame = +1
Query: 112 SLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 291
S+K+N+G+ MP +G GT + K + + V AIDVGYRH D+A + E+
Sbjct: 8 SVKLNDGKFMPILGFGTSVAR------KVAMSNVEEAVQVAIDVGYRHIDSAYTHLNEEG 61
Query: 292 IGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 471
IG+A++ K+ G VKR+DIF TTK+W T R V + + SLKKL L Y+DLYL H+P+
Sbjct: 62 IGQAIRKKIANGTVKRKDIFYTTKVWGTFSRPELVQRGLEMSLKKLQLSYMDLYLFHFPV 121
Query: 472 GL 477
L
Sbjct: 122 PL 123
>AK058142-1|BAB71682.1| 146|Homo sapiens protein ( Homo sapiens
cDNA FLJ25413 fis, clone TST03402, highly similar to
3-OXO-5-BETA-STEROID 4-DEHYDROGENASE (EC 1.3.99.6). ).
Length = 146
Score = 46.8 bits (106), Expect = 7e-05
Identities = 22/66 (33%), Positives = 38/66 (57%), Gaps = 2/66 (3%)
Frame = +1
Query: 463 WPIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTI--KPDA 636
+P N + + + TW +E + G+VK +G+SNFN++QLE +L + + KP +
Sbjct: 10 YPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHKPVS 69
Query: 637 IQIEVH 654
Q+E H
Sbjct: 70 NQVECH 75
>AB028065-1|BAA88489.1| 67|Homo sapiens prostaglandin F synthase
protein.
Length = 67
Score = 44.8 bits (101), Expect = 3e-04
Identities = 18/42 (42%), Positives = 27/42 (64%)
Frame = +1
Query: 502 VDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIK 627
VD TW +E + G+ K IG+SNFN++QLE +L + +K
Sbjct: 19 VDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLK 60
>AB037905-2|BAA92890.1| 45|Homo sapiens truncated aldo-keto
reductase protein.
Length = 45
Score = 39.9 bits (89), Expect = 0.008
Identities = 18/38 (47%), Positives = 24/38 (63%)
Frame = +1
Query: 364 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 477
+W T R V + + SLKKL L Y+DLYL H+P+ L
Sbjct: 1 VWGTFSRPELVQRGLEMSLKKLQLSYMDLYLFHFPVPL 38
>L35546-1|AAA65028.1| 274|Homo sapiens gamma-glutamylcysteine
synthetase light subunit protein.
Length = 274
Score = 37.1 bits (82), Expect = 0.055
Identities = 32/154 (20%), Positives = 71/154 (46%), Gaps = 5/154 (3%)
Frame = +1
Query: 205 KQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEE-GVVKREDIFITTKLWNTQ- 378
++L D + + ++ + V E + V VE+ +RE++ ++ KL+ +
Sbjct: 41 EELHDCIQKTLNEWSSQINPDLVREFPDVLECTVSHAVEKINPDEREEMKVSAKLFIVES 100
Query: 379 HRRTEVAQAINDSLKKLGLDYIDLYLMHWPI---GLNADYSHSDVDFMETWRGLEDAQRM 549
+ + A++ + LG+ +D ++ P G+N H W LE+ +
Sbjct: 101 NSSSSTRSAVDMACSVLGVAQLDSVIIASPPIEDGVNLSLEH----LQPYWEELENLVQS 156
Query: 550 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEV 651
+ IG S+ +K QLE++ + +KP++ Q+ +
Sbjct: 157 KKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQVNL 190
>CR541833-1|CAG46632.1| 274|Homo sapiens GCLM protein.
Length = 274
Score = 37.1 bits (82), Expect = 0.055
Identities = 32/154 (20%), Positives = 71/154 (46%), Gaps = 5/154 (3%)
Frame = +1
Query: 205 KQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEE-GVVKREDIFITTKLWNTQ- 378
++L D + + ++ + V E + V VE+ +RE++ ++ KL+ +
Sbjct: 41 EELHDCIQKTLNEWSSQINPDLVREFPDVLECTVSHAVEKINPDEREEMKVSAKLFIVES 100
Query: 379 HRRTEVAQAINDSLKKLGLDYIDLYLMHWPI---GLNADYSHSDVDFMETWRGLEDAQRM 549
+ + A++ + LG+ +D ++ P G+N H W LE+ +
Sbjct: 101 NSSSSTRSAVDMACSVLGVAQLDSVIIASPPIEDGVNLSLEH----LQPYWEELENLVQS 156
Query: 550 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEV 651
+ IG S+ +K QLE++ + +KP++ Q+ +
Sbjct: 157 KKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQVNL 190
>BC041809-1|AAH41809.1| 274|Homo sapiens glutamate-cysteine ligase,
modifier subunit protein.
Length = 274
Score = 37.1 bits (82), Expect = 0.055
Identities = 32/154 (20%), Positives = 71/154 (46%), Gaps = 5/154 (3%)
Frame = +1
Query: 205 KQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEE-GVVKREDIFITTKLWNTQ- 378
++L D + + ++ + V E + V VE+ +RE++ ++ KL+ +
Sbjct: 41 EELHDCIQKTLNEWSSQINPDLVREFPDVLECTVSHAVEKINPDEREEMKVSAKLFIVES 100
Query: 379 HRRTEVAQAINDSLKKLGLDYIDLYLMHWPI---GLNADYSHSDVDFMETWRGLEDAQRM 549
+ + A++ + LG+ +D ++ P G+N H W LE+ +
Sbjct: 101 NSSSSTRSAVDMACSVLGVAQLDSVIIASPPIEDGVNLSLEH----LQPYWEELENLVQS 156
Query: 550 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEV 651
+ IG S+ +K QLE++ + +KP++ Q+ +
Sbjct: 157 KKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQVNL 190
>AY773965-1|AAV28733.1| 274|Homo sapiens glutamate-cysteine ligase,
modifier subunit protein.
Length = 274
Score = 37.1 bits (82), Expect = 0.055
Identities = 32/154 (20%), Positives = 71/154 (46%), Gaps = 5/154 (3%)
Frame = +1
Query: 205 KQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEE-GVVKREDIFITTKLWNTQ- 378
++L D + + ++ + V E + V VE+ +RE++ ++ KL+ +
Sbjct: 41 EELHDCIQKTLNEWSSQINPDLVREFPDVLECTVSHAVEKINPDEREEMKVSAKLFIVES 100
Query: 379 HRRTEVAQAINDSLKKLGLDYIDLYLMHWPI---GLNADYSHSDVDFMETWRGLEDAQRM 549
+ + A++ + LG+ +D ++ P G+N H W LE+ +
Sbjct: 101 NSSSSTRSAVDMACSVLGVAQLDSVIIASPPIEDGVNLSLEH----LQPYWEELENLVQS 156
Query: 550 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEV 651
+ IG S+ +K QLE++ + +KP++ Q+ +
Sbjct: 157 KKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQVNL 190
>AL117351-10|CAI22976.1| 274|Homo sapiens glutamate-cysteine
ligase, modifier subunit protein.
Length = 274
Score = 37.1 bits (82), Expect = 0.055
Identities = 32/154 (20%), Positives = 71/154 (46%), Gaps = 5/154 (3%)
Frame = +1
Query: 205 KQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEE-GVVKREDIFITTKLWNTQ- 378
++L D + + ++ + V E + V VE+ +RE++ ++ KL+ +
Sbjct: 41 EELHDCIQKTLNEWSSQINPDLVREFPDVLECTVSHAVEKINPDEREEMKVSAKLFIVES 100
Query: 379 HRRTEVAQAINDSLKKLGLDYIDLYLMHWPI---GLNADYSHSDVDFMETWRGLEDAQRM 549
+ + A++ + LG+ +D ++ P G+N H W LE+ +
Sbjct: 101 NSSSSTRSAVDMACSVLGVAQLDSVIIASPPIEDGVNLSLEH----LQPYWEELENLVQS 156
Query: 550 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEV 651
+ IG S+ +K QLE++ + +KP++ Q+ +
Sbjct: 157 KKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQVNL 190
>AL049796-2|CAI21813.1| 274|Homo sapiens glutamate-cysteine ligase,
modifier subunit protein.
Length = 274
Score = 37.1 bits (82), Expect = 0.055
Identities = 32/154 (20%), Positives = 71/154 (46%), Gaps = 5/154 (3%)
Frame = +1
Query: 205 KQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEE-GVVKREDIFITTKLWNTQ- 378
++L D + + ++ + V E + V VE+ +RE++ ++ KL+ +
Sbjct: 41 EELHDCIQKTLNEWSSQINPDLVREFPDVLECTVSHAVEKINPDEREEMKVSAKLFIVES 100
Query: 379 HRRTEVAQAINDSLKKLGLDYIDLYLMHWPI---GLNADYSHSDVDFMETWRGLEDAQRM 549
+ + A++ + LG+ +D ++ P G+N H W LE+ +
Sbjct: 101 NSSSSTRSAVDMACSVLGVAQLDSVIIASPPIEDGVNLSLEH----LQPYWEELENLVQS 156
Query: 550 GIVKGIGLSNFNKQQLERVLKEGTIKPDAIQIEV 651
+ IG S+ +K QLE++ + +KP++ Q+ +
Sbjct: 157 KKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQVNL 190
>AF007190-1|AAC02268.1| 513|Homo sapiens intestinal mucin protein.
Length = 513
Score = 32.7 bits (71), Expect = 1.2
Identities = 24/64 (37%), Positives = 33/64 (51%), Gaps = 1/64 (1%)
Frame = -3
Query: 344 SSLLTTPSSTFIFTASPISCSVS*TEAVSK*RYPTSMARI-TTSRSCLSLDFTTPF*SNP 168
SSLLTT ST+ F++S + S T + P S I TT+ S L+ TT F ++P
Sbjct: 273 SSLLTTFPSTYSFSSSMSASSAGTTHTETISSLPASTNTIHTTAESALAPTTTTSFTTSP 332
Query: 167 RYVP 156
P
Sbjct: 333 TMEP 336
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 92,839,544
Number of Sequences: 237096
Number of extensions: 1962431
Number of successful extensions: 7922
Number of sequences better than 10.0: 100
Number of HSP's better than 10.0 without gapping: 7655
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7761
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 7366354010
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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