Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= bmov11n06
(710 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC039600-1|AAH39600.1| 1049|Homo sapiens hect domain and RLD 4 p... 118 3e-26
AY650033-1|AAV66579.1| 979|Homo sapiens HECT and RCC1 containin... 118 3e-26
AY221963-1|AAO65480.1| 1057|Homo sapiens HECT and RCC1 containin... 118 3e-26
AL356741-3|CAH74148.1| 1049|Homo sapiens hect domain and RLD 4 p... 118 3e-26
AL133551-3|CAI16032.1| 1049|Homo sapiens hect domain and RLD 4 p... 118 3e-26
D25215-1|BAA04945.2| 1054|Homo sapiens KIAA0032 protein. 109 1e-23
BC038960-1|AAH38960.1| 368|Homo sapiens HERC3 protein protein. 108 2e-23
AC098582-1|AAY41038.1| 382|Homo sapiens unknown protein. 108 2e-23
BC042047-1|AAH42047.2| 1022|Homo sapiens hect domain and RLD 6 p... 100 1e-20
AY653203-1|AAV66897.1| 322|Homo sapiens truncated HERC6 protein. 100 1e-20
AY653202-1|AAV66896.1| 364|Homo sapiens truncated HERC6 protein. 100 1e-20
AY653201-1|AAV66895.1| 986|Homo sapiens HERC6 splice variant pr... 100 1e-20
AF336798-1|AAQ14893.1| 1022|Homo sapiens HERC6 protein. 100 1e-20
AF071172-1|AAD08657.1| 4834|Homo sapiens HERC2 protein. 97 5e-20
AB027289-1|BAA88519.1| 1024|Homo sapiens cyclin-E binding protei... 91 3e-18
AF224249-1|AAO27475.1| 328|Homo sapiens HERC2 protein. 91 4e-18
AY337518-1|AAR00320.1| 1024|Homo sapiens HECT E3 ubiquitin ligas... 90 6e-18
AF225407-1|AAO27483.1| 409|Homo sapiens HERC2 protein. 86 1e-16
AB046813-1|BAB13419.1| 953|Homo sapiens KIAA1593 protein protein. 86 1e-16
AL356741-1|CAH74146.1| 907|Homo sapiens hect domain and RLD 4 p... 85 2e-16
AL133551-1|CAI16031.1| 907|Homo sapiens hect domain and RLD 4 p... 85 2e-16
BC029052-1|AAH29052.1| 551|Homo sapiens regulator of chromosome... 83 1e-15
AY341245-1|AAP88928.1| 551|Homo sapiens chromosome condensation... 83 1e-15
AL157813-1|CAH70795.1| 551|Homo sapiens regulator of chromosome... 83 1e-15
AK092403-1|BAC03879.1| 184|Homo sapiens protein ( Homo sapiens ... 83 1e-15
AF060219-1|AAC79987.1| 551|Homo sapiens RCC1-like G exchanging ... 83 1e-15
AB209543-1|BAD92780.1| 556|Homo sapiens RCC1-like G exchanging ... 83 1e-15
U50078-1|AAD12586.1| 4861|Homo sapiens p532 protein. 81 5e-15
BC065375-1|AAH65375.1| 458|Homo sapiens secretion regulating gu... 79 1e-14
AJ243951-1|CAB60833.1| 288|Homo sapiens deafness locus associat... 79 1e-14
AJ243950-1|CAB60832.1| 458|Homo sapiens deafness locus associat... 79 1e-14
AC004460-2|AAC06339.1| 371|Homo sapiens WUGSC:H_DJ1086D14.2 pro... 76 1e-13
AL139321-5|CAH71047.1| 531|Homo sapiens regulator of chromosome... 75 3e-13
AK096654-1|BAC04833.1| 531|Homo sapiens protein ( Homo sapiens ... 75 3e-13
AJ319660-1|CAC40027.1| 531|Homo sapiens guanine nucleotide exch... 75 3e-13
AF334406-1|AAK38372.1| 531|Homo sapiens CLLL7 protein protein. 75 3e-13
BC142946-1|AAI42947.1| 457|Homo sapiens RCC2 protein protein. 74 4e-13
BC053908-1|AAH53908.1| 522|Homo sapiens RCC2 protein protein. 74 4e-13
BC042141-1|AAH42141.1| 522|Homo sapiens regulator of chromosome... 74 4e-13
BC038104-1|AAH38104.1| 355|Homo sapiens RCBTB1 protein protein. 74 4e-13
AL359612-1|CAB94882.1| 333|Homo sapiens hypothetical protein pr... 74 4e-13
AJ421269-1|CAD13148.1| 522|Homo sapiens RCC1-like protein protein. 74 4e-13
AB040903-1|BAA95994.1| 564|Homo sapiens KIAA1470 protein protein. 74 4e-13
BC040929-1|AAH40929.1| 651|Homo sapiens HERC1 protein protein. 72 2e-12
X97668-1|CAA66258.1| 815|Homo sapiens XLRP3 protein. 71 3e-12
U57629-1|AAC50481.1| 815|Homo sapiens retinitis pigmentosa GTPa... 71 3e-12
BC031624-1|AAH31624.1| 480|Homo sapiens RPGR protein protein. 71 3e-12
AL606748-2|CAI95407.1| 815|Homo sapiens retinitis pigmentosa GT... 71 3e-12
AK223491-1|BAD97211.1| 815|Homo sapiens retinitis pigmentosa GT... 71 3e-12
AJ238395-1|CAB54002.1| 646|Homo sapiens RPGR protein protein. 71 3e-12
BC029174-1|AAH29174.1| 812|Homo sapiens ALS2 protein protein. 70 9e-12
AJ318463-1|CAC86116.1| 815|Homo sapiens retinitis pigmentosa GT... 69 1e-11
BC071576-1|AAH71576.1| 1237|Homo sapiens ALS2 protein protein. 65 2e-10
BC004933-1|AAH04933.1| 351|Homo sapiens RCC2 protein protein. 65 2e-10
AK023024-1|BAB14362.1| 396|Homo sapiens protein ( Homo sapiens ... 65 2e-10
AF391100-1|AAL14103.1| 1657|Homo sapiens alsin protein. 65 2e-10
AC007279-1|AAY15058.1| 1598|Homo sapiens unknown protein. 65 2e-10
AB053306-1|BAB69015.1| 396|Homo sapiens ALS2 protein. 65 2e-10
AB053305-1|BAB69014.1| 1657|Homo sapiens ALS2 protein. 65 2e-10
AB046783-1|BAB13389.2| 1658|Homo sapiens KIAA1563 protein protein. 65 2e-10
X12654-1|CAA31182.1| 421|Homo sapiens protein ( Human mRNA for ... 65 3e-10
X06130-1|CAA29496.1| 421|Homo sapiens protein ( Human mRNA for ... 65 3e-10
D00591-1|BAA00469.1| 421|Homo sapiens RCC1 protein. 65 3e-10
CR407693-1|CAG28621.1| 421|Homo sapiens CHC1 protein. 65 3e-10
BC069198-1|AAH69198.1| 452|Homo sapiens regulator of chromosome... 65 3e-10
BC036903-1|AAH36903.1| 421|Homo sapiens regulator of chromosome... 65 3e-10
BC010067-1|AAH10067.1| 421|Homo sapiens regulator of chromosome... 65 3e-10
BC007300-1|AAH07300.1| 421|Homo sapiens regulator of chromosome... 65 3e-10
AL513497-2|CAI22287.1| 421|Homo sapiens regulator of chromosome... 65 3e-10
AF498924-1|AAM21072.1| 421|Homo sapiens regulator of chromosome... 65 3e-10
BC040695-1|AAH40695.1| 358|Homo sapiens WBSCR16 protein protein. 62 2e-09
BC032712-1|AAH32712.1| 454|Homo sapiens WBSCR16 protein protein. 62 2e-09
BC019008-1|AAH19008.1| 464|Homo sapiens Williams-Beuren syndrom... 62 2e-09
BC007823-1|AAH07823.1| 464|Homo sapiens Williams-Beuren syndrom... 62 2e-09
AF410455-1|AAM62304.1| 464|Homo sapiens RCC1-like G exchanging ... 62 2e-09
DQ005634-1|AAY55907.1| 1196|Homo sapiens inhibitor of Bruton's t... 61 3e-09
DQ005633-1|AAY55906.1| 1353|Homo sapiens inhibitor of Bruton's t... 61 3e-09
BC113698-1|AAI13699.1| 1353|Homo sapiens inhibitor of Bruton aga... 61 3e-09
BC113696-1|AAI13697.1| 1353|Homo sapiens inhibitor of Bruton aga... 61 3e-09
AL050333-2|CAI23416.1| 1187|Homo sapiens RP1-93K22.1 protein. 61 3e-09
AB037838-1|BAA92655.2| 1379|Homo sapiens KIAA1417 protein protein. 61 3e-09
AY650032-1|AAV66578.1| 117|Homo sapiens HECT and RCC1 containin... 57 7e-08
AY650034-1|AAV66580.1| 110|Homo sapiens HECT and RCC1 containin... 56 2e-07
BC113705-1|AAI13706.1| 692|Homo sapiens NIMA (never in mitosis ... 55 3e-07
BC112240-1|AAI12241.1| 692|Homo sapiens NIMA-related kinase 8 p... 55 3e-07
AY267371-1|AAP04006.1| 692|Homo sapiens NIMA-family kinase NEK8... 55 3e-07
AY242354-1|AAO88243.1| 692|Homo sapiens NIMA-related kinase 12a... 55 3e-07
BC112101-1|AAI12102.1| 979|Homo sapiens NIMA related kinase 9 p... 54 7e-07
BC093881-1|AAH93881.1| 979|Homo sapiens NIMA (never in mitosis ... 54 7e-07
AY080896-1|AAL87410.1| 979|Homo sapiens NIMA-family kinase NERC... 54 7e-07
AY048580-1|AAL05428.1| 979|Homo sapiens NIMA-related kinase Nek... 54 7e-07
AC007055-4|AAD31939.1| 414|Homo sapiens protein ( Homo sapiens ... 54 7e-07
AB082526-1|BAC02704.1| 1011|Homo sapiens KIAA1995 protein protein. 54 7e-07
AF225404-1|AAO27482.1| 259|Homo sapiens HERC2 protein. 44 4e-04
AL359257-2|CAI39759.1| 4640|Homo sapiens AC001226.5 protein. 41 0.005
AL159158-1|CAI16842.1| 4640|Homo sapiens AC001226.5 protein. 41 0.005
AL159154-1|CAH73736.1| 4640|Homo sapiens AC001226.5 protein. 41 0.005
AF075587-1|AAC39928.1| 4641|Homo sapiens protein associated with... 41 0.005
BC113826-1|AAI13827.1| 244|Homo sapiens RCCD1 protein protein. 40 0.009
BC067293-1|AAH67293.1| 580|Homo sapiens F-box protein 24 protein. 34 0.44
AC069281-1|AAP21863.1| 580|Homo sapiens unknown protein. 34 0.44
>BC039600-1|AAH39600.1| 1049|Homo sapiens hect domain and RLD 4
protein.
Length = 1049
Score = 118 bits (283), Expect = 3e-26
Identities = 57/165 (34%), Positives = 96/165 (58%)
Frame = +3
Query: 216 MFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCG 395
M CWGNA+ +L + G ++V++P S + + ++ V G H++++ + G +Y+CG
Sbjct: 1 MLCWGNASFGQLGLGGID-EEIVLEPRKSDFFINKRVRDVGCGLRHTVFVLDDGTVYTCG 59
Query: 396 NNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQL 575
ND+GQLG + K P V I ++CG H+LA+++ GQ ++WG DS GQL
Sbjct: 60 CNDLGQLGHEKSR---KKPEQVVALDAQNIVAVSCGEAHTLALNDKGQVYAWGLDSDGQL 116
Query: 576 GNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
G P+ +K L+ ++QVACG YHS+AL+ + +++ W
Sbjct: 117 GLVGSEECIRVPRNIKSLSDIQIVQVACGYYHSLALSKASEVFCW 161
Score = 94.7 bits (225), Expect = 3e-19
Identities = 47/133 (35%), Positives = 72/133 (54%)
Frame = +3
Query: 312 ESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTIST 491
++ +I AV+ GE H+L L++ G +Y+ G + GQLG + + P +++ D I
Sbjct: 82 DAQNIVAVSCGEAHTLALNDKGQVYAWGLDSDGQLGLVGSEECIRVPRNIKSLSDIQIVQ 141
Query: 492 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 671
+ACG HSLA+ + + F WG + GQLG Q P+ +K L +QVA G H
Sbjct: 142 VACGYYHSLALSKASEVFCWGQNKYGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAAGGAH 201
Query: 672 SVALTNSGDLYSW 710
S LT SG ++ W
Sbjct: 202 SFVLTLSGAIFGW 214
Score = 87.0 bits (206), Expect = 6e-17
Identities = 49/171 (28%), Positives = 84/171 (49%)
Frame = +3
Query: 198 LQNYKKMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSG 377
L + +++ WG + +L + GS+ + + P K I VA G +HSL LS +
Sbjct: 99 LNDKGQVYAWGLDSDGQLGLVGSE--ECIRVPRNIKSLSDIQIVQVACGYYHSLALSKAS 156
Query: 378 HLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGS 557
++ G N GQLG T+ +P L+++ +A G HS + G F WG
Sbjct: 157 EVFCWGQNKYGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAAGGAHSFVLTLSGAIFGWGR 216
Query: 558 DSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
+ GQLG N + + P +K L ++ ++ + CG H+ ALT G ++++
Sbjct: 217 NKFGQLGLN-DENDRYVPNLLKSLRSQKIVYICCGEDHTAALTKEGGVFTF 266
Score = 85.8 bits (203), Expect = 1e-16
Identities = 57/172 (33%), Positives = 88/172 (51%), Gaps = 1/172 (0%)
Frame = +3
Query: 198 LQNYKKMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSG 377
L ++FCWG + +L + G+ P L K VAAG HS L+ SG
Sbjct: 152 LSKASEVFCWGQNKYGQLGL-GTDCKKQT-SPQLLKSLLGIPFMQVAAGGAHSFVLTLSG 209
Query: 378 HLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGS 557
++ G N GQLG E+D P L+++ + I I CG H+ A+ + G F++G+
Sbjct: 210 AIFGWGRNKFGQLGLNDENDRYV-PNLLKSLRSQKIVYICCGEDHTAALTKEGGVFTFGA 268
Query: 558 DSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA-LTNSGDLYSW 710
GQLG+N +H + P+ V L V ++ACG H+ A + +SG +YS+
Sbjct: 269 GGYGQLGHNSTSH-EINPRKVFELMGSIVTEIACGRQHTSAFVPSSGRIYSF 319
Score = 30.3 bits (65), Expect = 7.1
Identities = 18/48 (37%), Positives = 27/48 (56%), Gaps = 1/48 (2%)
Frame = +3
Query: 324 IQAVAAGEFH-SLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVE 464
+ +A G H S ++ +SG +YS G GQLG + S N K+P V+
Sbjct: 296 VTEIACGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTS-NRKSPFTVK 342
>AY650033-1|AAV66579.1| 979|Homo sapiens HECT and RCC1 containing
protein 4 isoform 3 protein.
Length = 979
Score = 118 bits (283), Expect = 3e-26
Identities = 57/165 (34%), Positives = 96/165 (58%)
Frame = +3
Query: 216 MFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCG 395
M CWGNA+ +L + G ++V++P S + + ++ V G H++++ + G +Y+CG
Sbjct: 1 MLCWGNASFGQLGLGGID-EEIVLEPRKSDFFINKRVRDVGCGLRHTVFVLDDGTVYTCG 59
Query: 396 NNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQL 575
ND+GQLG + K P V I ++CG H+LA+++ GQ ++WG DS GQL
Sbjct: 60 CNDLGQLGHEKSR---KKPEQVVALDAQNIVAVSCGEAHTLALNDKGQVYAWGLDSDGQL 116
Query: 576 GNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
G P+ +K L+ ++QVACG YHS+AL+ + +++ W
Sbjct: 117 GLVGSEECIRVPRNIKSLSDIQIVQVACGYYHSLALSKASEVFCW 161
Score = 94.7 bits (225), Expect = 3e-19
Identities = 47/133 (35%), Positives = 72/133 (54%)
Frame = +3
Query: 312 ESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTIST 491
++ +I AV+ GE H+L L++ G +Y+ G + GQLG + + P +++ D I
Sbjct: 82 DAQNIVAVSCGEAHTLALNDKGQVYAWGLDSDGQLGLVGSEECIRVPRNIKSLSDIQIVQ 141
Query: 492 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 671
+ACG HSLA+ + + F WG + GQLG Q P+ +K L +QVA G H
Sbjct: 142 VACGYYHSLALSKASEVFCWGQNKYGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAAGGAH 201
Query: 672 SVALTNSGDLYSW 710
S LT SG ++ W
Sbjct: 202 SFVLTLSGAIFGW 214
Score = 87.0 bits (206), Expect = 6e-17
Identities = 49/171 (28%), Positives = 84/171 (49%)
Frame = +3
Query: 198 LQNYKKMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSG 377
L + +++ WG + +L + GS+ + + P K I VA G +HSL LS +
Sbjct: 99 LNDKGQVYAWGLDSDGQLGLVGSE--ECIRVPRNIKSLSDIQIVQVACGYYHSLALSKAS 156
Query: 378 HLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGS 557
++ G N GQLG T+ +P L+++ +A G HS + G F WG
Sbjct: 157 EVFCWGQNKYGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAAGGAHSFVLTLSGAIFGWGR 216
Query: 558 DSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
+ GQLG N + + P +K L ++ ++ + CG H+ ALT G ++++
Sbjct: 217 NKFGQLGLN-DENDRYVPNLLKSLRSQKIVYICCGEDHTAALTKEGGVFTF 266
Score = 85.8 bits (203), Expect = 1e-16
Identities = 57/172 (33%), Positives = 88/172 (51%), Gaps = 1/172 (0%)
Frame = +3
Query: 198 LQNYKKMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSG 377
L ++FCWG + +L + G+ P L K VAAG HS L+ SG
Sbjct: 152 LSKASEVFCWGQNKYGQLGL-GTDCKKQT-SPQLLKSLLGIPFMQVAAGGAHSFVLTLSG 209
Query: 378 HLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGS 557
++ G N GQLG E+D P L+++ + I I CG H+ A+ + G F++G+
Sbjct: 210 AIFGWGRNKFGQLGLNDENDRYV-PNLLKSLRSQKIVYICCGEDHTAALTKEGGVFTFGA 268
Query: 558 DSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA-LTNSGDLYSW 710
GQLG+N +H + P+ V L V ++ACG H+ A + +SG +YS+
Sbjct: 269 GGYGQLGHNSTSH-EINPRKVFELMGSIVTEIACGRQHTSAFVPSSGRIYSF 319
Score = 30.3 bits (65), Expect = 7.1
Identities = 18/48 (37%), Positives = 27/48 (56%), Gaps = 1/48 (2%)
Frame = +3
Query: 324 IQAVAAGEFH-SLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVE 464
+ +A G H S ++ +SG +YS G GQLG + S N K+P V+
Sbjct: 296 VTEIACGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTS-NRKSPFTVK 342
>AY221963-1|AAO65480.1| 1057|Homo sapiens HECT and RCC1 containing
protein 4 isoform 1 protein.
Length = 1057
Score = 118 bits (283), Expect = 3e-26
Identities = 57/165 (34%), Positives = 96/165 (58%)
Frame = +3
Query: 216 MFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCG 395
M CWGNA+ +L + G ++V++P S + + ++ V G H++++ + G +Y+CG
Sbjct: 1 MLCWGNASFGQLGLGGID-EEIVLEPRKSDFFINKRVRDVGCGLRHTVFVLDDGTVYTCG 59
Query: 396 NNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQL 575
ND+GQLG + K P V I ++CG H+LA+++ GQ ++WG DS GQL
Sbjct: 60 CNDLGQLGHEKSR---KKPEQVVALDAQNIVAVSCGEAHTLALNDKGQVYAWGLDSDGQL 116
Query: 576 GNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
G P+ +K L+ ++QVACG YHS+AL+ + +++ W
Sbjct: 117 GLVGSEECIRVPRNIKSLSDIQIVQVACGYYHSLALSKASEVFCW 161
Score = 94.7 bits (225), Expect = 3e-19
Identities = 47/133 (35%), Positives = 72/133 (54%)
Frame = +3
Query: 312 ESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTIST 491
++ +I AV+ GE H+L L++ G +Y+ G + GQLG + + P +++ D I
Sbjct: 82 DAQNIVAVSCGEAHTLALNDKGQVYAWGLDSDGQLGLVGSEECIRVPRNIKSLSDIQIVQ 141
Query: 492 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 671
+ACG HSLA+ + + F WG + GQLG Q P+ +K L +QVA G H
Sbjct: 142 VACGYYHSLALSKASEVFCWGQNKYGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAAGGAH 201
Query: 672 SVALTNSGDLYSW 710
S LT SG ++ W
Sbjct: 202 SFVLTLSGAIFGW 214
Score = 87.0 bits (206), Expect = 6e-17
Identities = 49/171 (28%), Positives = 84/171 (49%)
Frame = +3
Query: 198 LQNYKKMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSG 377
L + +++ WG + +L + GS+ + + P K I VA G +HSL LS +
Sbjct: 99 LNDKGQVYAWGLDSDGQLGLVGSE--ECIRVPRNIKSLSDIQIVQVACGYYHSLALSKAS 156
Query: 378 HLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGS 557
++ G N GQLG T+ +P L+++ +A G HS + G F WG
Sbjct: 157 EVFCWGQNKYGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAAGGAHSFVLTLSGAIFGWGR 216
Query: 558 DSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
+ GQLG N + + P +K L ++ ++ + CG H+ ALT G ++++
Sbjct: 217 NKFGQLGLN-DENDRYVPNLLKSLRSQKIVYICCGEDHTAALTKEGGVFTF 266
Score = 85.8 bits (203), Expect = 1e-16
Identities = 57/172 (33%), Positives = 88/172 (51%), Gaps = 1/172 (0%)
Frame = +3
Query: 198 LQNYKKMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSG 377
L ++FCWG + +L + G+ P L K VAAG HS L+ SG
Sbjct: 152 LSKASEVFCWGQNKYGQLGL-GTDCKKQT-SPQLLKSLLGIPFMQVAAGGAHSFVLTLSG 209
Query: 378 HLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGS 557
++ G N GQLG E+D P L+++ + I I CG H+ A+ + G F++G+
Sbjct: 210 AIFGWGRNKFGQLGLNDENDRYV-PNLLKSLRSQKIVYICCGEDHTAALTKEGGVFTFGA 268
Query: 558 DSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA-LTNSGDLYSW 710
GQLG+N +H + P+ V L V ++ACG H+ A + +SG +YS+
Sbjct: 269 GGYGQLGHNSTSH-EINPRKVFELMGSIVTEIACGRQHTSAFVPSSGRIYSF 319
Score = 30.3 bits (65), Expect = 7.1
Identities = 18/48 (37%), Positives = 27/48 (56%), Gaps = 1/48 (2%)
Frame = +3
Query: 324 IQAVAAGEFH-SLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVE 464
+ +A G H S ++ +SG +YS G GQLG + S N K+P V+
Sbjct: 296 VTEIACGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTS-NRKSPFTVK 342
>AL356741-3|CAH74148.1| 1049|Homo sapiens hect domain and RLD 4
protein.
Length = 1049
Score = 118 bits (283), Expect = 3e-26
Identities = 57/165 (34%), Positives = 96/165 (58%)
Frame = +3
Query: 216 MFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCG 395
M CWGNA+ +L + G ++V++P S + + ++ V G H++++ + G +Y+CG
Sbjct: 1 MLCWGNASFGQLGLGGID-EEIVLEPRKSDFFINKRVRDVGCGLRHTVFVLDDGTVYTCG 59
Query: 396 NNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQL 575
ND+GQLG + K P V I ++CG H+LA+++ GQ ++WG DS GQL
Sbjct: 60 CNDLGQLGHEKSR---KKPEQVVALDAQNIVAVSCGEAHTLALNDKGQVYAWGLDSDGQL 116
Query: 576 GNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
G P+ +K L+ ++QVACG YHS+AL+ + +++ W
Sbjct: 117 GLVGSEECIRVPRNIKSLSDIQIVQVACGYYHSLALSKASEVFCW 161
Score = 94.7 bits (225), Expect = 3e-19
Identities = 47/133 (35%), Positives = 72/133 (54%)
Frame = +3
Query: 312 ESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTIST 491
++ +I AV+ GE H+L L++ G +Y+ G + GQLG + + P +++ D I
Sbjct: 82 DAQNIVAVSCGEAHTLALNDKGQVYAWGLDSDGQLGLVGSEECIRVPRNIKSLSDIQIVQ 141
Query: 492 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 671
+ACG HSLA+ + + F WG + GQLG Q P+ +K L +QVA G H
Sbjct: 142 VACGYYHSLALSKASEVFCWGQNKYGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAAGGAH 201
Query: 672 SVALTNSGDLYSW 710
S LT SG ++ W
Sbjct: 202 SFVLTLSGAIFGW 214
Score = 87.0 bits (206), Expect = 6e-17
Identities = 49/171 (28%), Positives = 84/171 (49%)
Frame = +3
Query: 198 LQNYKKMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSG 377
L + +++ WG + +L + GS+ + + P K I VA G +HSL LS +
Sbjct: 99 LNDKGQVYAWGLDSDGQLGLVGSE--ECIRVPRNIKSLSDIQIVQVACGYYHSLALSKAS 156
Query: 378 HLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGS 557
++ G N GQLG T+ +P L+++ +A G HS + G F WG
Sbjct: 157 EVFCWGQNKYGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAAGGAHSFVLTLSGAIFGWGR 216
Query: 558 DSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
+ GQLG N + + P +K L ++ ++ + CG H+ ALT G ++++
Sbjct: 217 NKFGQLGLN-DENDRYVPNLLKSLRSQKIVYICCGEDHTAALTKEGGVFTF 266
Score = 85.8 bits (203), Expect = 1e-16
Identities = 57/172 (33%), Positives = 88/172 (51%), Gaps = 1/172 (0%)
Frame = +3
Query: 198 LQNYKKMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSG 377
L ++FCWG + +L + G+ P L K VAAG HS L+ SG
Sbjct: 152 LSKASEVFCWGQNKYGQLGL-GTDCKKQT-SPQLLKSLLGIPFMQVAAGGAHSFVLTLSG 209
Query: 378 HLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGS 557
++ G N GQLG E+D P L+++ + I I CG H+ A+ + G F++G+
Sbjct: 210 AIFGWGRNKFGQLGLNDENDRYV-PNLLKSLRSQKIVYICCGEDHTAALTKEGGVFTFGA 268
Query: 558 DSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA-LTNSGDLYSW 710
GQLG+N +H + P+ V L V ++ACG H+ A + +SG +YS+
Sbjct: 269 GGYGQLGHNSTSH-EINPRKVFELMGSIVTEIACGRQHTSAFVPSSGRIYSF 319
Score = 30.3 bits (65), Expect = 7.1
Identities = 18/48 (37%), Positives = 27/48 (56%), Gaps = 1/48 (2%)
Frame = +3
Query: 324 IQAVAAGEFH-SLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVE 464
+ +A G H S ++ +SG +YS G GQLG + S N K+P V+
Sbjct: 296 VTEIACGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTS-NRKSPFTVK 342
>AL133551-3|CAI16032.1| 1049|Homo sapiens hect domain and RLD 4
protein.
Length = 1049
Score = 118 bits (283), Expect = 3e-26
Identities = 57/165 (34%), Positives = 96/165 (58%)
Frame = +3
Query: 216 MFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCG 395
M CWGNA+ +L + G ++V++P S + + ++ V G H++++ + G +Y+CG
Sbjct: 1 MLCWGNASFGQLGLGGID-EEIVLEPRKSDFFINKRVRDVGCGLRHTVFVLDDGTVYTCG 59
Query: 396 NNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQL 575
ND+GQLG + K P V I ++CG H+LA+++ GQ ++WG DS GQL
Sbjct: 60 CNDLGQLGHEKSR---KKPEQVVALDAQNIVAVSCGEAHTLALNDKGQVYAWGLDSDGQL 116
Query: 576 GNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
G P+ +K L+ ++QVACG YHS+AL+ + +++ W
Sbjct: 117 GLVGSEECIRVPRNIKSLSDIQIVQVACGYYHSLALSKASEVFCW 161
Score = 94.7 bits (225), Expect = 3e-19
Identities = 47/133 (35%), Positives = 72/133 (54%)
Frame = +3
Query: 312 ESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTIST 491
++ +I AV+ GE H+L L++ G +Y+ G + GQLG + + P +++ D I
Sbjct: 82 DAQNIVAVSCGEAHTLALNDKGQVYAWGLDSDGQLGLVGSEECIRVPRNIKSLSDIQIVQ 141
Query: 492 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH 671
+ACG HSLA+ + + F WG + GQLG Q P+ +K L +QVA G H
Sbjct: 142 VACGYYHSLALSKASEVFCWGQNKYGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAAGGAH 201
Query: 672 SVALTNSGDLYSW 710
S LT SG ++ W
Sbjct: 202 SFVLTLSGAIFGW 214
Score = 87.0 bits (206), Expect = 6e-17
Identities = 49/171 (28%), Positives = 84/171 (49%)
Frame = +3
Query: 198 LQNYKKMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSG 377
L + +++ WG + +L + GS+ + + P K I VA G +HSL LS +
Sbjct: 99 LNDKGQVYAWGLDSDGQLGLVGSE--ECIRVPRNIKSLSDIQIVQVACGYYHSLALSKAS 156
Query: 378 HLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGS 557
++ G N GQLG T+ +P L+++ +A G HS + G F WG
Sbjct: 157 EVFCWGQNKYGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAAGGAHSFVLTLSGAIFGWGR 216
Query: 558 DSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
+ GQLG N + + P +K L ++ ++ + CG H+ ALT G ++++
Sbjct: 217 NKFGQLGLN-DENDRYVPNLLKSLRSQKIVYICCGEDHTAALTKEGGVFTF 266
Score = 85.8 bits (203), Expect = 1e-16
Identities = 57/172 (33%), Positives = 88/172 (51%), Gaps = 1/172 (0%)
Frame = +3
Query: 198 LQNYKKMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSG 377
L ++FCWG + +L + G+ P L K VAAG HS L+ SG
Sbjct: 152 LSKASEVFCWGQNKYGQLGL-GTDCKKQT-SPQLLKSLLGIPFMQVAAGGAHSFVLTLSG 209
Query: 378 HLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGS 557
++ G N GQLG E+D P L+++ + I I CG H+ A+ + G F++G+
Sbjct: 210 AIFGWGRNKFGQLGLNDENDRYV-PNLLKSLRSQKIVYICCGEDHTAALTKEGGVFTFGA 268
Query: 558 DSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA-LTNSGDLYSW 710
GQLG+N +H + P+ V L V ++ACG H+ A + +SG +YS+
Sbjct: 269 GGYGQLGHNSTSH-EINPRKVFELMGSIVTEIACGRQHTSAFVPSSGRIYSF 319
Score = 30.3 bits (65), Expect = 7.1
Identities = 18/48 (37%), Positives = 27/48 (56%), Gaps = 1/48 (2%)
Frame = +3
Query: 324 IQAVAAGEFH-SLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVE 464
+ +A G H S ++ +SG +YS G GQLG + S N K+P V+
Sbjct: 296 VTEIACGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTS-NRKSPFTVK 342
>D25215-1|BAA04945.2| 1054|Homo sapiens KIAA0032 protein.
Length = 1054
Score = 109 bits (261), Expect = 1e-23
Identities = 56/167 (33%), Positives = 89/167 (53%)
Frame = +3
Query: 210 KKMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYS 389
+ M CWG + + I + + +V +P + + ++ VA G HS++L G +Y+
Sbjct: 3 RTMLCWGYWSLGQPGIS-TNLQGIVAEPQVCGFISDRSVKEVACGGNHSVFLLEDGEVYT 61
Query: 390 CGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMG 569
CG N GQLG + E G P + D I +ACG HSLA+ + GQ FSWG+ S G
Sbjct: 62 CGLNTKGQLGHERE---GNKPEQIGALADQHIIHVACGESHSLALSDRGQLFSWGAGSDG 118
Query: 570 QLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
QLG + P+ ++ L + ++QV+CG +H +AL G ++W
Sbjct: 119 QLGLMTTEDSVAVPRLIQKLNQQTILQVSCGNWHCLALAADGQFFTW 165
Score = 99 bits (238), Expect = 8e-21
Identities = 55/130 (42%), Positives = 72/130 (55%)
Frame = +3
Query: 321 HIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIAC 500
HI VA GE HSL LS+ G L+S G GQLG T D+ P L++ TI ++C
Sbjct: 89 HIIHVACGESHSLALSDRGQLFSWGAGSDGQLGLMTTEDSVAVPRLIQKLNQQTILQVSC 148
Query: 501 GLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA 680
G H LA+ GQ F+WG +S GQLG +Q P+ V+ L + QVA G HS A
Sbjct: 149 GNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAHSFA 208
Query: 681 LTNSGDLYSW 710
L+ SG ++ W
Sbjct: 209 LSLSGAVFGW 218
Score = 89.0 bits (211), Expect = 1e-17
Identities = 51/171 (29%), Positives = 87/171 (50%)
Frame = +3
Query: 198 LQNYKKMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSG 377
L + ++F WG + +L + ++ D V P L + I V+ G +H L L+ G
Sbjct: 103 LSDRGQLFSWGAGSDGQLGLMTTE--DSVAVPRLIQKLNQQTILQVSCGNWHCLALAADG 160
Query: 378 HLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGS 557
++ G N GQLG E + +P V + + ++ +A G HS A+ G F WG
Sbjct: 161 QFFTWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAHSFALSLSGAVFGWGM 220
Query: 558 DSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
++ GQLG + ++ P VK L T+ V+ ++CG H+ LT SG ++++
Sbjct: 221 NNAGQLGLS-DEKDRESPCHVKLLRTQKVVYISCGEEHTAVLTKSGGVFTF 270
Score = 84.2 bits (199), Expect = 4e-16
Identities = 53/167 (31%), Positives = 89/167 (53%), Gaps = 1/167 (0%)
Frame = +3
Query: 213 KMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 392
+ F WG +H +L + G + P + E + VAAG HS LS SG ++
Sbjct: 161 QFFTWGKNSHGQLGL-GKEFPSQA-SPQRVRSLEGIPLAQVAAGGAHSFALSLSGAVFGW 218
Query: 393 GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQ 572
G N+ GQLG E D ++P V+ + + I+CG +H+ + + G F++G+ S GQ
Sbjct: 219 GMNNAGQLGLSDEKDR-ESPCHVKLLRTQKVVYISCGEEHTAVLTKSGGVFTFGAGSCGQ 277
Query: 573 LGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA-LTNSGDLYSW 710
LG++ + + P+ V L V Q+ACG H++A + +SG +Y++
Sbjct: 278 LGHD-SMNDEVNPRRVLELMGSEVTQIACGRQHTLAFVPSSGLIYAF 323
>BC038960-1|AAH38960.1| 368|Homo sapiens HERC3 protein protein.
Length = 368
Score = 108 bits (260), Expect = 2e-23
Identities = 56/165 (33%), Positives = 88/165 (53%)
Frame = +3
Query: 216 MFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCG 395
M CWG + + I + + +V +P + + ++ VA G HS++L G +Y+CG
Sbjct: 1 MLCWGYWSLGQPGIS-TNLQGIVAEPQVCGFISDRSVKEVACGGNHSVFLLEDGEVYTCG 59
Query: 396 NNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQL 575
N GQLG + E G P + D I +ACG HSLA+ + GQ FSWG+ S GQL
Sbjct: 60 LNTKGQLGHERE---GNKPEQIGALADQHIIHVACGESHSLALSDRGQLFSWGAGSDGQL 116
Query: 576 GNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
G + P+ ++ L + ++QV+CG +H +AL G ++W
Sbjct: 117 GLMTTEDSVAVPRLIQKLNQQTILQVSCGNWHCLALAADGQFFTW 161
Score = 99 bits (238), Expect = 8e-21
Identities = 55/130 (42%), Positives = 72/130 (55%)
Frame = +3
Query: 321 HIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIAC 500
HI VA GE HSL LS+ G L+S G GQLG T D+ P L++ TI ++C
Sbjct: 85 HIIHVACGESHSLALSDRGQLFSWGAGSDGQLGLMTTEDSVAVPRLIQKLNQQTILQVSC 144
Query: 501 GLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA 680
G H LA+ GQ F+WG +S GQLG +Q P+ V+ L + QVA G HS A
Sbjct: 145 GNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAHSFA 204
Query: 681 LTNSGDLYSW 710
L+ SG ++ W
Sbjct: 205 LSLSGAVFGW 214
Score = 89.0 bits (211), Expect = 1e-17
Identities = 51/171 (29%), Positives = 87/171 (50%)
Frame = +3
Query: 198 LQNYKKMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSG 377
L + ++F WG + +L + ++ D V P L + I V+ G +H L L+ G
Sbjct: 99 LSDRGQLFSWGAGSDGQLGLMTTE--DSVAVPRLIQKLNQQTILQVSCGNWHCLALAADG 156
Query: 378 HLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGS 557
++ G N GQLG E + +P V + + ++ +A G HS A+ G F WG
Sbjct: 157 QFFTWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAHSFALSLSGAVFGWGM 216
Query: 558 DSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
++ GQLG + ++ P VK L T+ V+ ++CG H+ LT SG ++++
Sbjct: 217 NNAGQLGLS-DEKDRESPCHVKLLRTQKVVYISCGEEHTAVLTKSGGVFTF 266
Score = 84.2 bits (199), Expect = 4e-16
Identities = 53/167 (31%), Positives = 89/167 (53%), Gaps = 1/167 (0%)
Frame = +3
Query: 213 KMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 392
+ F WG +H +L + G + P + E + VAAG HS LS SG ++
Sbjct: 157 QFFTWGKNSHGQLGL-GKEFPSQA-SPQRVRSLEGIPLAQVAAGGAHSFALSLSGAVFGW 214
Query: 393 GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQ 572
G N+ GQLG E D ++P V+ + + I+CG +H+ + + G F++G+ S GQ
Sbjct: 215 GMNNAGQLGLSDEKDR-ESPCHVKLLRTQKVVYISCGEEHTAVLTKSGGVFTFGAGSCGQ 273
Query: 573 LGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA-LTNSGDLYSW 710
LG++ + + P+ V L V Q+ACG H++A + +SG +Y++
Sbjct: 274 LGHD-SMNDEVNPRRVLELMGSEVTQIACGRQHTLAFVPSSGLIYAF 319
>AC098582-1|AAY41038.1| 382|Homo sapiens unknown protein.
Length = 382
Score = 108 bits (260), Expect = 2e-23
Identities = 56/165 (33%), Positives = 88/165 (53%)
Frame = +3
Query: 216 MFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCG 395
M CWG + + I + + +V +P + + ++ VA G HS++L G +Y+CG
Sbjct: 1 MLCWGYWSLGQPGIS-TNLQGIVAEPQVCGFISDRSVKEVACGGNHSVFLLEDGEVYTCG 59
Query: 396 NNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQL 575
N GQLG + E G P + D I +ACG HSLA+ + GQ FSWG+ S GQL
Sbjct: 60 LNTKGQLGHERE---GNKPEQIGALADQHIIHVACGESHSLALSDRGQLFSWGAGSDGQL 116
Query: 576 GNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
G + P+ ++ L + ++QV+CG +H +AL G ++W
Sbjct: 117 GLMTTEDSVAVPRLIQKLNQQTILQVSCGNWHCLALAADGQFFTW 161
Score = 99 bits (238), Expect = 8e-21
Identities = 55/130 (42%), Positives = 72/130 (55%)
Frame = +3
Query: 321 HIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIAC 500
HI VA GE HSL LS+ G L+S G GQLG T D+ P L++ TI ++C
Sbjct: 85 HIIHVACGESHSLALSDRGQLFSWGAGSDGQLGLMTTEDSVAVPRLIQKLNQQTILQVSC 144
Query: 501 GLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA 680
G H LA+ GQ F+WG +S GQLG +Q P+ V+ L + QVA G HS A
Sbjct: 145 GNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAHSFA 204
Query: 681 LTNSGDLYSW 710
L+ SG ++ W
Sbjct: 205 LSLSGAVFGW 214
Score = 89.0 bits (211), Expect = 1e-17
Identities = 51/171 (29%), Positives = 87/171 (50%)
Frame = +3
Query: 198 LQNYKKMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSG 377
L + ++F WG + +L + ++ D V P L + I V+ G +H L L+ G
Sbjct: 99 LSDRGQLFSWGAGSDGQLGLMTTE--DSVAVPRLIQKLNQQTILQVSCGNWHCLALAADG 156
Query: 378 HLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGS 557
++ G N GQLG E + +P V + + ++ +A G HS A+ G F WG
Sbjct: 157 QFFTWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAHSFALSLSGAVFGWGM 216
Query: 558 DSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
++ GQLG + ++ P VK L T+ V+ ++CG H+ LT SG ++++
Sbjct: 217 NNAGQLGLS-DEKDRESPCHVKLLRTQKVVYISCGEEHTAVLTKSGGVFTF 266
Score = 84.2 bits (199), Expect = 4e-16
Identities = 53/167 (31%), Positives = 89/167 (53%), Gaps = 1/167 (0%)
Frame = +3
Query: 213 KMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 392
+ F WG +H +L + G + P + E + VAAG HS LS SG ++
Sbjct: 157 QFFTWGKNSHGQLGL-GKEFPSQA-SPQRVRSLEGIPLAQVAAGGAHSFALSLSGAVFGW 214
Query: 393 GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQ 572
G N+ GQLG E D ++P V+ + + I+CG +H+ + + G F++G+ S GQ
Sbjct: 215 GMNNAGQLGLSDEKDR-ESPCHVKLLRTQKVVYISCGEEHTAVLTKSGGVFTFGAGSCGQ 273
Query: 573 LGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA-LTNSGDLYSW 710
LG++ + + P+ V L V Q+ACG H++A + +SG +Y++
Sbjct: 274 LGHD-SMNDEVNPRRVLELMGSEVTQIACGRQHTLAFVPSSGLIYAF 319
>BC042047-1|AAH42047.2| 1022|Homo sapiens hect domain and RLD 6
protein.
Length = 1022
Score = 99.5 bits (237), Expect = 1e-20
Identities = 48/125 (38%), Positives = 73/125 (58%)
Frame = +3
Query: 336 AAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHS 515
A+GE HSL L + + SCG+N GQLGR+ + G+ P ++ + + ++CG +HS
Sbjct: 29 ASGERHSLLLLTNHRVLSCGDNSRGQLGRR-GAQRGELPEPIQALETLIVDLVSCGKEHS 87
Query: 516 LAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSG 695
LA+ G+ F+WG+ S GQLG PK + L +IQV+CG YHS+AL+
Sbjct: 88 LAVCHKGRVFAWGAGSEGQLGIGEFKEISFTPKKIMTLNDIKIIQVSCGHYHSLALSKDS 147
Query: 696 DLYSW 710
++SW
Sbjct: 148 QVFSW 152
Score = 87.8 bits (208), Expect = 3e-17
Identities = 51/169 (30%), Positives = 82/169 (48%), Gaps = 3/169 (1%)
Frame = +3
Query: 213 KMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 392
++F WG + +L I + ++ P I V+ G +HSL LS ++S
Sbjct: 95 RVFAWGAGSEGQLGI--GEFKEISFTPKKIMTLNDIKIIQVSCGHYHSLALSKDSQVFSW 152
Query: 393 GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQ 572
G N GQLG E + +P V + + ++ +A G HS A+ G F WGS+S GQ
Sbjct: 153 GKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAHSFALSLCGTSFGWGSNSAGQ 212
Query: 573 L---GNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
L G N+ + +KP V L V+ ++CG H+ LT G ++++
Sbjct: 213 LALSGRNVPVQS-NKPLSVGALKNLGVVYISCGDAHTAVLTQDGKVFTF 260
Score = 85.8 bits (203), Expect = 1e-16
Identities = 55/171 (32%), Positives = 86/171 (50%)
Frame = +3
Query: 198 LQNYKKMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSG 377
L N++ + C G+ + +L G+Q +L P + E+ + V+ G+ HSL + + G
Sbjct: 39 LTNHRVLSC-GDNSRGQLGRRGAQRGEL---PEPIQALETLIVDLVSCGKEHSLAVCHKG 94
Query: 378 HLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGS 557
+++ G GQLG + P + T D I ++CG HSLA+ + Q FSWG
Sbjct: 95 RVFAWGAGSEGQLGIGEFKEISFTPKKIMTLNDIKIIQVSCGHYHSLALSKDSQVFSWGK 154
Query: 558 DSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
+S GQLG +Q P+ V+ L + QVA G HS AL+ G + W
Sbjct: 155 NSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAHSFALSLCGTSFGW 205
Score = 66.9 bits (156), Expect = 7e-11
Identities = 49/168 (29%), Positives = 81/168 (48%), Gaps = 3/168 (1%)
Frame = +3
Query: 198 LQNYKKMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSG 377
L ++F WG +H +L + G + P + E + VAAG HS LS G
Sbjct: 143 LSKDSQVFSWGKNSHGQLGL-GKEFPSQA-SPQRVRSLEGIPLAQVAAGGAHSFALSLCG 200
Query: 378 HLYSCGNNDVGQL---GRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFS 548
+ G+N GQL GR + K P V K+ + I+CG H+ + + G+ F+
Sbjct: 201 TSFGWGSNSAGQLALSGRNVPVQSNK-PLSVGALKNLGVVYISCGDAHTAVLTQDGKVFT 259
Query: 549 WGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNS 692
+G + GQLG + + P+ V+ + V Q+ CG+YH++A ++
Sbjct: 260 FGDNRSGQLGYSPTPEKRG-PQLVERI-DGLVSQIDCGSYHTLAYVHT 305
>AY653203-1|AAV66897.1| 322|Homo sapiens truncated HERC6 protein.
Length = 322
Score = 99.5 bits (237), Expect = 1e-20
Identities = 48/125 (38%), Positives = 73/125 (58%)
Frame = +3
Query: 336 AAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHS 515
A+GE HSL L + + SCG+N GQLGR+ + G+ P ++ + + ++CG +HS
Sbjct: 29 ASGERHSLLLLTNHRVLSCGDNSRGQLGRR-GAQRGELPEPIQALETLIVDLVSCGKEHS 87
Query: 516 LAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSG 695
LA+ G+ F+WG+ S GQLG PK + L +IQV+CG YHS+AL+
Sbjct: 88 LAVCHKGRVFAWGAGSEGQLGIGEFKEISFTPKKIMTLNDIKIIQVSCGHYHSLALSKDS 147
Query: 696 DLYSW 710
++SW
Sbjct: 148 QVFSW 152
Score = 87.8 bits (208), Expect = 3e-17
Identities = 51/169 (30%), Positives = 82/169 (48%), Gaps = 3/169 (1%)
Frame = +3
Query: 213 KMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 392
++F WG + +L I + ++ P I V+ G +HSL LS ++S
Sbjct: 95 RVFAWGAGSEGQLGI--GEFKEISFTPKKIMTLNDIKIIQVSCGHYHSLALSKDSQVFSW 152
Query: 393 GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQ 572
G N GQLG E + +P V + + ++ +A G HS A+ G F WGS+S GQ
Sbjct: 153 GKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAHSFALSLCGTSFGWGSNSAGQ 212
Query: 573 L---GNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
L G N+ + +KP V L V+ ++CG H+ LT G ++++
Sbjct: 213 LALSGRNVPVQS-NKPLSVGALKNLGVVYISCGDAHTAVLTQDGKVFTF 260
Score = 85.8 bits (203), Expect = 1e-16
Identities = 55/171 (32%), Positives = 86/171 (50%)
Frame = +3
Query: 198 LQNYKKMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSG 377
L N++ + C G+ + +L G+Q +L P + E+ + V+ G+ HSL + + G
Sbjct: 39 LTNHRVLSC-GDNSRGQLGRRGAQRGEL---PEPIQALETLIVDLVSCGKEHSLAVCHKG 94
Query: 378 HLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGS 557
+++ G GQLG + P + T D I ++CG HSLA+ + Q FSWG
Sbjct: 95 RVFAWGAGSEGQLGIGEFKEISFTPKKIMTLNDIKIIQVSCGHYHSLALSKDSQVFSWGK 154
Query: 558 DSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
+S GQLG +Q P+ V+ L + QVA G HS AL+ G + W
Sbjct: 155 NSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAHSFALSLCGTSFGW 205
Score = 57.6 bits (133), Expect = 4e-08
Identities = 40/130 (30%), Positives = 61/130 (46%), Gaps = 3/130 (2%)
Frame = +3
Query: 198 LQNYKKMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSG 377
L ++F WG +H +L + G + P + E + VAAG HS LS G
Sbjct: 143 LSKDSQVFSWGKNSHGQLGL-GKEFPSQA-SPQRVRSLEGIPLAQVAAGGAHSFALSLCG 200
Query: 378 HLYSCGNNDVGQL---GRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFS 548
+ G+N GQL GR + K P V K+ + I+CG H+ + + G+ F+
Sbjct: 201 TSFGWGSNSAGQLALSGRNVPVQSNK-PLSVGALKNLGVVYISCGDAHTAVLTQDGKVFT 259
Query: 549 WGSDSMGQLG 578
+G + GQLG
Sbjct: 260 FGDNRSGQLG 269
>AY653202-1|AAV66896.1| 364|Homo sapiens truncated HERC6 protein.
Length = 364
Score = 99.5 bits (237), Expect = 1e-20
Identities = 48/125 (38%), Positives = 73/125 (58%)
Frame = +3
Query: 336 AAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHS 515
A+GE HSL L + + SCG+N GQLGR+ + G+ P ++ + + ++CG +HS
Sbjct: 29 ASGERHSLLLLTNHRVLSCGDNSRGQLGRR-GAQRGELPEPIQALETLIVDLVSCGKEHS 87
Query: 516 LAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSG 695
LA+ G+ F+WG+ S GQLG PK + L +IQV+CG YHS+AL+
Sbjct: 88 LAVCHKGRVFAWGAGSEGQLGIGEFKEISFTPKKIMTLNDIKIIQVSCGHYHSLALSKDS 147
Query: 696 DLYSW 710
++SW
Sbjct: 148 QVFSW 152
Score = 87.8 bits (208), Expect = 3e-17
Identities = 51/169 (30%), Positives = 82/169 (48%), Gaps = 3/169 (1%)
Frame = +3
Query: 213 KMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 392
++F WG + +L I + ++ P I V+ G +HSL LS ++S
Sbjct: 95 RVFAWGAGSEGQLGI--GEFKEISFTPKKIMTLNDIKIIQVSCGHYHSLALSKDSQVFSW 152
Query: 393 GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQ 572
G N GQLG E + +P V + + ++ +A G HS A+ G F WGS+S GQ
Sbjct: 153 GKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAHSFALSLCGTSFGWGSNSAGQ 212
Query: 573 L---GNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
L G N+ + +KP V L V+ ++CG H+ LT G ++++
Sbjct: 213 LALSGRNVPVQS-NKPLSVGALKNLGVVYISCGDAHTAVLTQDGKVFTF 260
Score = 85.8 bits (203), Expect = 1e-16
Identities = 55/171 (32%), Positives = 86/171 (50%)
Frame = +3
Query: 198 LQNYKKMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSG 377
L N++ + C G+ + +L G+Q +L P + E+ + V+ G+ HSL + + G
Sbjct: 39 LTNHRVLSC-GDNSRGQLGRRGAQRGEL---PEPIQALETLIVDLVSCGKEHSLAVCHKG 94
Query: 378 HLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGS 557
+++ G GQLG + P + T D I ++CG HSLA+ + Q FSWG
Sbjct: 95 RVFAWGAGSEGQLGIGEFKEISFTPKKIMTLNDIKIIQVSCGHYHSLALSKDSQVFSWGK 154
Query: 558 DSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
+S GQLG +Q P+ V+ L + QVA G HS AL+ G + W
Sbjct: 155 NSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAHSFALSLCGTSFGW 205
Score = 66.9 bits (156), Expect = 7e-11
Identities = 49/168 (29%), Positives = 81/168 (48%), Gaps = 3/168 (1%)
Frame = +3
Query: 198 LQNYKKMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSG 377
L ++F WG +H +L + G + P + E + VAAG HS LS G
Sbjct: 143 LSKDSQVFSWGKNSHGQLGL-GKEFPSQA-SPQRVRSLEGIPLAQVAAGGAHSFALSLCG 200
Query: 378 HLYSCGNNDVGQL---GRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFS 548
+ G+N GQL GR + K P V K+ + I+CG H+ + + G+ F+
Sbjct: 201 TSFGWGSNSAGQLALSGRNVPVQSNK-PLSVGALKNLGVVYISCGDAHTAVLTQDGKVFT 259
Query: 549 WGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNS 692
+G + GQLG + + P+ V+ + V Q+ CG+YH++A ++
Sbjct: 260 FGDNRSGQLGYSPTPEKRG-PQLVERI-DGLVSQIDCGSYHTLAYVHT 305
>AY653201-1|AAV66895.1| 986|Homo sapiens HERC6 splice variant
protein.
Length = 986
Score = 99.5 bits (237), Expect = 1e-20
Identities = 48/125 (38%), Positives = 73/125 (58%)
Frame = +3
Query: 336 AAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHS 515
A+GE HSL L + + SCG+N GQLGR+ + G+ P ++ + + ++CG +HS
Sbjct: 29 ASGERHSLLLLTNHRVLSCGDNSRGQLGRR-GAQRGELPEPIQALETLIVDLVSCGKEHS 87
Query: 516 LAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSG 695
LA+ G+ F+WG+ S GQLG PK + L +IQV+CG YHS+AL+
Sbjct: 88 LAVCHKGRVFAWGAGSEGQLGIGEFKEISFTPKKIMTLNDIKIIQVSCGHYHSLALSKDS 147
Query: 696 DLYSW 710
++SW
Sbjct: 148 QVFSW 152
Score = 87.8 bits (208), Expect = 3e-17
Identities = 51/169 (30%), Positives = 82/169 (48%), Gaps = 3/169 (1%)
Frame = +3
Query: 213 KMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 392
++F WG + +L I + ++ P I V+ G +HSL LS ++S
Sbjct: 95 RVFAWGAGSEGQLGI--GEFKEISFTPKKIMTLNDIKIIQVSCGHYHSLALSKDSQVFSW 152
Query: 393 GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQ 572
G N GQLG E + +P V + + ++ +A G HS A+ G F WGS+S GQ
Sbjct: 153 GKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAHSFALSLCGTSFGWGSNSAGQ 212
Query: 573 L---GNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
L G N+ + +KP V L V+ ++CG H+ LT G ++++
Sbjct: 213 LALSGRNVPVQS-NKPLSVGALKNLGVVYISCGDAHTAVLTQDGKVFTF 260
Score = 85.8 bits (203), Expect = 1e-16
Identities = 55/171 (32%), Positives = 86/171 (50%)
Frame = +3
Query: 198 LQNYKKMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSG 377
L N++ + C G+ + +L G+Q +L P + E+ + V+ G+ HSL + + G
Sbjct: 39 LTNHRVLSC-GDNSRGQLGRRGAQRGEL---PEPIQALETLIVDLVSCGKEHSLAVCHKG 94
Query: 378 HLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGS 557
+++ G GQLG + P + T D I ++CG HSLA+ + Q FSWG
Sbjct: 95 RVFAWGAGSEGQLGIGEFKEISFTPKKIMTLNDIKIIQVSCGHYHSLALSKDSQVFSWGK 154
Query: 558 DSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
+S GQLG +Q P+ V+ L + QVA G HS AL+ G + W
Sbjct: 155 NSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAHSFALSLCGTSFGW 205
Score = 66.9 bits (156), Expect = 7e-11
Identities = 49/168 (29%), Positives = 81/168 (48%), Gaps = 3/168 (1%)
Frame = +3
Query: 198 LQNYKKMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSG 377
L ++F WG +H +L + G + P + E + VAAG HS LS G
Sbjct: 143 LSKDSQVFSWGKNSHGQLGL-GKEFPSQA-SPQRVRSLEGIPLAQVAAGGAHSFALSLCG 200
Query: 378 HLYSCGNNDVGQL---GRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFS 548
+ G+N GQL GR + K P V K+ + I+CG H+ + + G+ F+
Sbjct: 201 TSFGWGSNSAGQLALSGRNVPVQSNK-PLSVGALKNLGVVYISCGDAHTAVLTQDGKVFT 259
Query: 549 WGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNS 692
+G + GQLG + + P+ V+ + V Q+ CG+YH++A ++
Sbjct: 260 FGDNRSGQLGYSPTPEKRG-PQLVERI-DGLVSQIDCGSYHTLAYVHT 305
>AF336798-1|AAQ14893.1| 1022|Homo sapiens HERC6 protein.
Length = 1022
Score = 99.5 bits (237), Expect = 1e-20
Identities = 48/125 (38%), Positives = 73/125 (58%)
Frame = +3
Query: 336 AAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHS 515
A+GE HSL L + + SCG+N GQLGR+ + G+ P ++ + + ++CG +HS
Sbjct: 29 ASGERHSLLLLTNHRVLSCGDNSRGQLGRR-GAQRGELPEPIQALETLIVDLVSCGKEHS 87
Query: 516 LAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSG 695
LA+ G+ F+WG+ S GQLG PK + L +IQV+CG YHS+AL+
Sbjct: 88 LAVCHKGRVFAWGAGSEGQLGIGEFKEISFTPKKIMTLNDIKIIQVSCGHYHSLALSKDS 147
Query: 696 DLYSW 710
++SW
Sbjct: 148 QVFSW 152
Score = 87.8 bits (208), Expect = 3e-17
Identities = 51/169 (30%), Positives = 82/169 (48%), Gaps = 3/169 (1%)
Frame = +3
Query: 213 KMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 392
++F WG + +L I + ++ P I V+ G +HSL LS ++S
Sbjct: 95 RVFAWGAGSEGQLGI--GEFKEISFTPKKIMTLNDIKIIQVSCGHYHSLALSKDSQVFSW 152
Query: 393 GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQ 572
G N GQLG E + +P V + + ++ +A G HS A+ G F WGS+S GQ
Sbjct: 153 GKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAHSFALSLCGTSFGWGSNSAGQ 212
Query: 573 L---GNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
L G N+ + +KP V L V+ ++CG H+ LT G ++++
Sbjct: 213 LALSGRNVPVQS-NKPLSVGALKNLGVVYISCGDAHTAVLTQDGKVFTF 260
Score = 85.8 bits (203), Expect = 1e-16
Identities = 55/171 (32%), Positives = 86/171 (50%)
Frame = +3
Query: 198 LQNYKKMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSG 377
L N++ + C G+ + +L G+Q +L P + E+ + V+ G+ HSL + + G
Sbjct: 39 LTNHRVLSC-GDNSRGQLGRRGAQRGEL---PEPIQALETLIVDLVSCGKEHSLAVCHKG 94
Query: 378 HLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGS 557
+++ G GQLG + P + T D I ++CG HSLA+ + Q FSWG
Sbjct: 95 RVFAWGAGSEGQLGIGEFKEISFTPKKIMTLNDIKIIQVSCGHYHSLALSKDSQVFSWGK 154
Query: 558 DSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
+S GQLG +Q P+ V+ L + QVA G HS AL+ G + W
Sbjct: 155 NSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAHSFALSLCGTSFGW 205
Score = 66.9 bits (156), Expect = 7e-11
Identities = 49/168 (29%), Positives = 81/168 (48%), Gaps = 3/168 (1%)
Frame = +3
Query: 198 LQNYKKMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSG 377
L ++F WG +H +L + G + P + E + VAAG HS LS G
Sbjct: 143 LSKDSQVFSWGKNSHGQLGL-GKEFPSQA-SPQRVRSLEGIPLAQVAAGGAHSFALSLCG 200
Query: 378 HLYSCGNNDVGQL---GRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFS 548
+ G+N GQL GR + K P V K+ + I+CG H+ + + G+ F+
Sbjct: 201 TSFGWGSNSAGQLALSGRNVPVQSNK-PLSVGALKNLGVVYISCGDAHTAVLTQDGKVFT 259
Query: 549 WGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNS 692
+G + GQLG + + P+ V+ + V Q+ CG+YH++A ++
Sbjct: 260 FGDNRSGQLGYSPTPEKRG-PQLVERI-DGLVSQIDCGSYHTLAYVHT 305
>AF071172-1|AAD08657.1| 4834|Homo sapiens HERC2 protein.
Length = 4834
Score = 97.1 bits (231), Expect = 5e-20
Identities = 57/178 (32%), Positives = 94/178 (52%), Gaps = 1/178 (0%)
Frame = +3
Query: 180 SSY*KKLQNYKKMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQ-AVAAGEFHS 356
S+Y + +++ WG + L S+ D I ++ K I A +G+ +
Sbjct: 560 STYSAAITAEGELYTWGRGNYGRLGHGSSE--DEAIPMLVAGLKGLKVIDVACGSGDAQT 617
Query: 357 LYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWG 536
L ++ +G ++S G+ D G+LGR SD K P L+E +D + + CG Q S+A+ + G
Sbjct: 618 LAVTENGQVWSWGDGDYGKLGRGG-SDGCKTPKLIEKLQDLDVVKVRCGSQFSIALTKDG 676
Query: 537 QPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
Q +SWG +LG+ H + PK ++GL K VI VA G+ H +ALT +++SW
Sbjct: 677 QVYSWGKGDNQRLGHGTEEHVR-YPKLLEGLQGKKVIDVAAGSTHCLALTEDSEVHSW 733
Score = 91.1 bits (216), Expect = 4e-18
Identities = 58/179 (32%), Positives = 93/179 (51%), Gaps = 2/179 (1%)
Frame = +3
Query: 180 SSY*KKLQNYKKMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAG--EFH 353
SS+ L + +++ WG + L G T L KP + K + VA G +
Sbjct: 3108 SSHSAALTSSGELYTWGLGEYGRLG-HGDNTTQL--KPKMVKVLLGHRVIQVACGSRDAQ 3164
Query: 354 SLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEW 533
+L L++ G ++S G+ D G+LGR S+ P +E + I CG Q SLA+ +
Sbjct: 3165 TLALTDEGLVFSWGDGDFGKLGRGG-SEGCNIPQNIERLNGQGVCQIECGAQFSLALTKS 3223
Query: 534 GQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
G ++WG +LG+ H + KP+ V+GL K ++ VA GA H +A+T+SG +Y+W
Sbjct: 3224 GVVWTWGKGDYFRLGHGSDVHVR-KPQVVEGLRGKKIVHVAVGALHCLAVTDSGQVYAW 3281
Score = 87.4 bits (207), Expect = 4e-17
Identities = 53/169 (31%), Positives = 86/169 (50%), Gaps = 3/169 (1%)
Frame = +3
Query: 213 KMFCWGNATHHELC-IDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYS 389
K+F WG +L + GS+I P+ S+ + ++ VA G ++ G +Y+
Sbjct: 2960 KVFVWGLNDKDQLGGLKGSKIK----VPSFSETLSALNVVQVAGGSKSLFAVTVEGKVYA 3015
Query: 390 CGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIAC--GLQHSLAIDEWGQPFSWGSDS 563
CG G+LG S P + + +A G +H+ A+ G+ FSWG
Sbjct: 3016 CGEATNGRLGLGISSGTVPIPRQITALSSYVVKKVAVHSGGRHATALTVDGKVFSWGEGD 3075
Query: 564 MGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
G+LG+ + DKP+ ++ L TK + +ACG+ HS ALT+SG+LY+W
Sbjct: 3076 DGKLGHFSRMNC-DKPRLIEALKTKRIRDIACGSSHSAALTSSGELYTW 3123
Score = 85.8 bits (203), Expect = 1e-16
Identities = 51/129 (39%), Positives = 72/129 (55%), Gaps = 2/129 (1%)
Frame = +3
Query: 330 AVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQ 509
AV +G H+ L+ G ++S G D G+LG + + K P L+E K I IACG
Sbjct: 3051 AVHSGGRHATALTVDGKVFSWGEGDDGKLGHFSRMNCDK-PRLIEALKTKRIRDIACGSS 3109
Query: 510 HSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGA--YHSVAL 683
HS A+ G+ ++WG G+LG+ Q KPK VK L VIQVACG+ ++AL
Sbjct: 3110 HSAALTSSGELYTWGLGEYGRLGHGDNT-TQLKPKMVKVLLGHRVIQVACGSRDAQTLAL 3168
Query: 684 TNSGDLYSW 710
T+ G ++SW
Sbjct: 3169 TDEGLVFSW 3177
Score = 85.8 bits (203), Expect = 1e-16
Identities = 48/167 (28%), Positives = 88/167 (52%), Gaps = 2/167 (1%)
Frame = +3
Query: 216 MFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVA--AGEFHSLYLSNSGHLYS 389
++ WG + L G ++ +KP L + + + +A +G+ +L L++ ++S
Sbjct: 4112 LYTWGKGRYGRL---GHSDSEDQLKPKLVEALQGHRVVDIACGSGDAQTLCLTDDDTVWS 4168
Query: 390 CGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMG 569
G+ D G+LGR SD K P +++ + + CG Q S+A+ + G ++WG
Sbjct: 4169 WGDGDYGKLGRGG-SDGCKVPMKIDSLTGLGVVKVECGSQFSVALTKSGAVYTWGKGDYH 4227
Query: 570 QLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
+LG+ H + +P+ V+GL K VI +A G+ H V T G++Y+W
Sbjct: 4228 RLGHGSDDHVR-RPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVYTW 4273
Score = 79.0 bits (186), Expect = 2e-14
Identities = 53/173 (30%), Positives = 81/173 (46%), Gaps = 2/173 (1%)
Frame = +3
Query: 198 LQNYKKMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSG 377
L + +++ WG A +L D +P + + + VAAG HS ++ +G
Sbjct: 4054 LSSEGEVYSWGEAEDGKLGHGNRSPCD---RPRVIESLRGIEVVDVAAGGAHSACVTAAG 4110
Query: 378 HLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGL--QHSLAIDEWGQPFSW 551
LY+ G G+LG D K P LVE + + IACG +L + + +SW
Sbjct: 4111 DLYTWGKGRYGRLGHSDSEDQLK-PKLVEALQGHRVVDIACGSGDAQTLCLTDDDTVWSW 4169
Query: 552 GSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
G G+LG G+ P + L V++V CG+ SVALT SG +Y+W
Sbjct: 4170 GDGDYGKLGRG-GSDGCKVPMKIDSLTGLGVVKVECGSQFSVALTKSGAVYTW 4221
Score = 76.2 bits (179), Expect = 1e-13
Identities = 48/157 (30%), Positives = 79/157 (50%)
Frame = +3
Query: 216 MFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCG 395
+F WG+ +L GS+ ++ P + + + G SL L+ SG +++ G
Sbjct: 3174 VFSWGDGDFGKLGRGGSEGCNI---PQNIERLNGQGVCQIECGAQFSLALTKSGVVWTWG 3230
Query: 396 NNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQL 575
D +LG ++ + + P +VE + I +A G H LA+ + GQ ++WG + GQ
Sbjct: 3231 KGDYFRLGHGSDV-HVRKPQVVEGLRGKKIVHVAVGALHCLAVTDSGQVYAWGDNDHGQQ 3289
Query: 576 GNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALT 686
GN KP V+GL + + +VACG+ HSVA T
Sbjct: 3290 GNGT-TTVNRKPTLVQGLEGQKITRVACGSSHSVAWT 3325
Score = 70.1 bits (164), Expect = 7e-12
Identities = 39/120 (32%), Positives = 65/120 (54%)
Frame = +3
Query: 333 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQH 512
V G S+ L+ SG +Y+ G D +LG ++ D+ + P V+ + + IA G H
Sbjct: 4202 VECGSQFSVALTKSGAVYTWGKGDYHRLGHGSD-DHVRRPRQVQGLQGKKVIAIATGSLH 4260
Query: 513 SLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNS 692
+ E G+ ++WG + GQLG+ +A +P+ V L K V +VACG+ H++A + S
Sbjct: 4261 CVCCTEDGEVYTWGDNDEGQLGDGT-TNAIQRPRLVAALQGKKVNRVACGSAHTLAWSTS 4319
Score = 68.9 bits (161), Expect = 2e-11
Identities = 43/126 (34%), Positives = 67/126 (53%), Gaps = 3/126 (2%)
Frame = +3
Query: 342 GEFHSLYLSNSGHLYSCGNNDVGQLG-RQTESDNGKNPALVETFKDCTISTIAC--GLQH 512
GE ++ G LY+ G G+LG TES + P L+E+ + I +A G +H
Sbjct: 3993 GEQTLFAVTADGKLYATGYGAGGRLGIGGTESVS--TPTLLESIQHVFIKKVAVNSGGKH 4050
Query: 513 SLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNS 692
LA+ G+ +SWG G+LG+ + D+P+ ++ L V+ VA G HS +T +
Sbjct: 4051 CLALSSEGEVYSWGEAEDGKLGHGNRSPC-DRPRVIESLRGIEVVDVAAGGAHSACVTAA 4109
Query: 693 GDLYSW 710
GDLY+W
Sbjct: 4110 GDLYTW 4115
Score = 65.7 bits (153), Expect = 2e-10
Identities = 47/150 (31%), Positives = 77/150 (51%), Gaps = 8/150 (5%)
Frame = +3
Query: 285 IKPTLSKWKESDHIQAVAAGE--FHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPAL 458
+ P L + S +I +AA H L L+ +G +YS G D G+LG ++ + P +
Sbjct: 482 LAPQLVQGLASRNIVKIAAHSDGHHYLALAATGEVYSWGCGDGGRLGHG-DTVPLEEPKV 540
Query: 459 VETFKDCT----ISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKG 626
+ F + IACG +S AI G+ ++WG + G+LG+ + + P V G
Sbjct: 541 ISAFSGKQAGKHVVHIACGSTYSAAITAEGELYTWGRGNYGRLGHG-SSEDEAIPMLVAG 599
Query: 627 LATKNVIQVACGA--YHSVALTNSGDLYSW 710
L VI VACG+ ++A+T +G ++SW
Sbjct: 600 LKGLKVIDVACGSGDAQTLAVTENGQVWSW 629
Score = 57.2 bits (132), Expect = 5e-08
Identities = 31/102 (30%), Positives = 52/102 (50%)
Frame = +3
Query: 216 MFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCG 395
++ WG +H L G D V +P + + + A+A G H + + G +Y+ G
Sbjct: 4218 VYTWGKGDYHRL---GHGSDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVYTWG 4274
Query: 396 NNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLA 521
+ND GQLG T ++ + P LV + ++ +ACG H+LA
Sbjct: 4275 DNDEGQLGDGT-TNAIQRPRLVAALQGKKVNRVACGSAHTLA 4315
Score = 53.6 bits (123), Expect = 7e-07
Identities = 33/107 (30%), Positives = 54/107 (50%), Gaps = 6/107 (5%)
Frame = +3
Query: 408 GQLGRQTESDNGKNPALVETFKDCTISTIACGLQ--HSLAIDEWGQPFSWGSDSMGQLGN 581
G++ Q + + P LV+ I IA H LA+ G+ +SWG G+LG+
Sbjct: 470 GRVYTQAYNSDTLAPQLVQGLASRNIVKIAAHSDGHHYLALAATGEVYSWGCGDGGRLGH 529
Query: 582 NLGAHAQDKPKFVKGL----ATKNVIQVACGAYHSVALTNSGDLYSW 710
++PK + A K+V+ +ACG+ +S A+T G+LY+W
Sbjct: 530 G-DTVPLEEPKVISAFSGKQAGKHVVHIACGSTYSAAITAEGELYTW 575
Score = 44.4 bits (100), Expect = 4e-04
Identities = 34/121 (28%), Positives = 55/121 (45%), Gaps = 2/121 (1%)
Frame = +3
Query: 354 SLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEW 533
+L SG +Y G+N GQLG E K P E + G Q A+
Sbjct: 3945 TLSAGGSGTIYGWGHNHRGQLG-GIEGAKVKVPTPCEALATLRPVQLIGGEQTLFAVTAD 4003
Query: 534 GQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVA--CGAYHSVALTNSGDLYS 707
G+ ++ G + G+LG G + P ++ + + +VA G H +AL++ G++YS
Sbjct: 4004 GKLYATGYGAGGRLGIG-GTESVSTPTLLESIQHVFIKKVAVNSGGKHCLALSSEGEVYS 4062
Query: 708 W 710
W
Sbjct: 4063 W 4063
Score = 34.3 bits (75), Expect = 0.44
Identities = 31/113 (27%), Positives = 44/113 (38%)
Frame = +3
Query: 213 KMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 392
+++ WG + L G + V P L + + + VAAG H L L+ ++S
Sbjct: 677 QVYSWGKGDNQRL---GHGTEEHVRYPKLLEGLQGKKVIDVAAGSTHCLALTEDSEVHSW 733
Query: 393 GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSW 551
G+ND Q T PA + I IACG S A W W
Sbjct: 734 GSNDQCQ-HFDTLRVTKPEPAALPGLDTKHIVGIACGPAQSFA---WSSCSEW 782
>AB027289-1|BAA88519.1| 1024|Homo sapiens cyclin-E binding protein 1
protein.
Length = 1024
Score = 91.5 bits (217), Expect = 3e-18
Identities = 55/168 (32%), Positives = 94/168 (55%), Gaps = 2/168 (1%)
Frame = +3
Query: 213 KMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 392
++F WG H +L + G + P + + + ++AGE HS+ LS SG++YS
Sbjct: 158 ELFAWGQNLHGQLGV-GRKFPSTTT-PQIVEHLAGVPLAQISAGEAHSMALSMSGNIYSW 215
Query: 393 GNNDVGQLGR-QTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMG 569
G N+ GQLG TES + +P+L+E + + +ACG HS + + G F++G+ G
Sbjct: 216 GKNECGQLGLGHTESKD--DPSLIEGLDNQKVEFVACGGSHSALLTQDGLLFTFGAGKHG 273
Query: 570 QLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA-LTNSGDLYSW 710
QLG+N + +P V L V Q+ACG +H++A +++ G ++S+
Sbjct: 274 QLGHN-STQNELRPCLVAELVGYRVTQIACGRWHTLAYVSDLGKVFSF 320
Score = 88.6 bits (210), Expect = 2e-17
Identities = 47/127 (37%), Positives = 70/127 (55%), Gaps = 1/127 (0%)
Frame = +3
Query: 333 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQH 512
+ G++HSL LS G L++ G N GQLG + + P +VE ++ I+ G H
Sbjct: 143 ITCGDYHSLALSKGGELFAWGQNLHGQLGVGRKFPSTTTPQIVEHLAGVPLAQISAGEAH 202
Query: 513 SLAIDEWGQPFSWGSDSMGQLGNNLG-AHAQDKPKFVKGLATKNVIQVACGAYHSVALTN 689
S+A+ G +SWG + GQLG LG ++D P ++GL + V VACG HS LT
Sbjct: 203 SMALSMSGNIYSWGKNECGQLG--LGHTESKDDPSLIEGLDNQKVEFVACGGSHSALLTQ 260
Query: 690 SGDLYSW 710
G L+++
Sbjct: 261 DGLLFTF 267
Score = 66.1 bits (154), Expect = 1e-10
Identities = 45/137 (32%), Positives = 69/137 (50%), Gaps = 1/137 (0%)
Frame = +3
Query: 216 MFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCG 395
++ WG +L + ++ D P+L + ++ ++ VA G HS L+ G L++ G
Sbjct: 212 IYSWGKNECGQLGLGHTESKD---DPSLIEGLDNQKVEFVACGGSHSALLTQDGLLFTFG 268
Query: 396 NNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLA-IDEWGQPFSWGSDSMGQ 572
GQLG + + N P LV ++ IACG H+LA + + G+ FS+GS GQ
Sbjct: 269 AGKHGQLGHNS-TQNELRPCLVAELVGYRVTQIACGRWHTLAYVSDLGKVFSFGSGKDGQ 327
Query: 573 LGNNLGAHAQDKPKFVK 623
LGN G Q P VK
Sbjct: 328 LGNG-GTRDQLMPLPVK 343
Score = 65.3 bits (152), Expect = 2e-10
Identities = 36/100 (36%), Positives = 55/100 (55%), Gaps = 2/100 (2%)
Frame = +3
Query: 417 GRQTESDNG--KNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLG 590
G+ E DN K+ ++ I I CG HSLA+ + G+ F+WG + GQLG
Sbjct: 116 GKPFEYDNYSMKHLRFESILQEKKIIQITCGDYHSLALSKGGELFAWGQNLHGQLGVGRK 175
Query: 591 AHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
+ P+ V+ LA + Q++ G HS+AL+ SG++YSW
Sbjct: 176 FPSTTTPQIVEHLAGVPLAQISAGEAHSMALSMSGNIYSW 215
>AF224249-1|AAO27475.1| 328|Homo sapiens HERC2 protein.
Length = 328
Score = 91.1 bits (216), Expect = 4e-18
Identities = 58/179 (32%), Positives = 93/179 (51%), Gaps = 2/179 (1%)
Frame = +3
Query: 180 SSY*KKLQNYKKMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAG--EFH 353
SS+ L + +++ WG + L G T L KP + K + VA G +
Sbjct: 146 SSHSAALTSSGELYTWGLGEYGRLG-HGDNTTQL--KPKMVKVLLGHRVIQVACGSRDAQ 202
Query: 354 SLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEW 533
+L L++ G ++S G+ D G+LGR S+ P +E + I CG Q SLA+ +
Sbjct: 203 TLALTDEGLVFSWGDGDFGKLGRGG-SEGCNIPQNIERLNGQGVCQIECGAQFSLALTKS 261
Query: 534 GQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
G ++WG +LG+ H + KP+ V+GL K ++ VA GA H +A+T+SG +Y+W
Sbjct: 262 GVVWTWGKGDYFRLGHGSDVHVR-KPQVVEGLRGKKIVHVAVGALHCLAVTDSGQVYAW 319
Score = 83.0 bits (196), Expect = 1e-15
Identities = 50/129 (38%), Positives = 71/129 (55%), Gaps = 2/129 (1%)
Frame = +3
Query: 330 AVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQ 509
AV +G H+ L+ G ++ G D G+LG + + K P L+E K I IACG
Sbjct: 89 AVHSGGRHATALTVDGKVFWWGEGDDGKLGHFSRMNCDK-PRLIEALKTKRIRDIACGSS 147
Query: 510 HSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGA--YHSVAL 683
HS A+ G+ ++WG G+LG+ Q KPK VK L VIQVACG+ ++AL
Sbjct: 148 HSAALTSSGELYTWGLGEYGRLGHGDNT-TQLKPKMVKVLLGHRVIQVACGSRDAQTLAL 206
Query: 684 TNSGDLYSW 710
T+ G ++SW
Sbjct: 207 TDEGLVFSW 215
Score = 81.4 bits (192), Expect = 3e-15
Identities = 44/142 (30%), Positives = 73/142 (51%), Gaps = 2/142 (1%)
Frame = +3
Query: 291 PTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETF 470
P+ S+ + ++ VA G ++ G +Y+CG G+LG S P +
Sbjct: 21 PSFSETLSALNVVQVAGGSKSLFAVTVEGKVYACGEATNGRLGLGISSGTVPIPRQITAL 80
Query: 471 KDCTISTIAC--GLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNV 644
+ +A G +H+ A+ G+ F WG G+LG+ + DKP+ ++ L TK +
Sbjct: 81 SSYVVKKVAVHSGGRHATALTVDGKVFWWGEGDDGKLGHFSRMNC-DKPRLIEALKTKRI 139
Query: 645 IQVACGAYHSVALTNSGDLYSW 710
+ACG+ HS ALT+SG+LY+W
Sbjct: 140 RDIACGSSHSAALTSSGELYTW 161
>AY337518-1|AAR00320.1| 1024|Homo sapiens HECT E3 ubiquitin ligase
protein.
Length = 1024
Score = 90.2 bits (214), Expect = 6e-18
Identities = 55/168 (32%), Positives = 93/168 (55%), Gaps = 2/168 (1%)
Frame = +3
Query: 213 KMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 392
++F WG H +L + G + P + + + ++AGE HS LS SG++YS
Sbjct: 158 ELFAWGQNLHGQLGV-GRKFPSTTT-PQIVEHLAGVPLAQISAGEAHSTALSMSGNIYSW 215
Query: 393 GNNDVGQLGR-QTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMG 569
G N+ GQLG TES + +P+L+E + + +ACG HS + + G F++G+ G
Sbjct: 216 GKNECGQLGLGHTESKD--DPSLIEGLDNQKVEFVACGGSHSALLTQDGLLFTFGAGKHG 273
Query: 570 QLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA-LTNSGDLYSW 710
QLG+N + +P V L V Q+ACG +H++A +++ G ++S+
Sbjct: 274 QLGHN-STQNELRPCLVAELVGYRVTQIACGRWHTLAYVSDLGKVFSF 320
Score = 87.4 bits (207), Expect = 4e-17
Identities = 47/127 (37%), Positives = 69/127 (54%), Gaps = 1/127 (0%)
Frame = +3
Query: 333 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQH 512
+ G++HSL LS G L++ G N GQLG + + P +VE ++ I+ G H
Sbjct: 143 ITCGDYHSLALSKGGELFAWGQNLHGQLGVGRKFPSTTTPQIVEHLAGVPLAQISAGEAH 202
Query: 513 SLAIDEWGQPFSWGSDSMGQLGNNLG-AHAQDKPKFVKGLATKNVIQVACGAYHSVALTN 689
S A+ G +SWG + GQLG LG ++D P ++GL + V VACG HS LT
Sbjct: 203 STALSMSGNIYSWGKNECGQLG--LGHTESKDDPSLIEGLDNQKVEFVACGGSHSALLTQ 260
Query: 690 SGDLYSW 710
G L+++
Sbjct: 261 DGLLFTF 267
Score = 66.1 bits (154), Expect = 1e-10
Identities = 45/137 (32%), Positives = 69/137 (50%), Gaps = 1/137 (0%)
Frame = +3
Query: 216 MFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCG 395
++ WG +L + ++ D P+L + ++ ++ VA G HS L+ G L++ G
Sbjct: 212 IYSWGKNECGQLGLGHTESKD---DPSLIEGLDNQKVEFVACGGSHSALLTQDGLLFTFG 268
Query: 396 NNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLA-IDEWGQPFSWGSDSMGQ 572
GQLG + + N P LV ++ IACG H+LA + + G+ FS+GS GQ
Sbjct: 269 AGKHGQLGHNS-TQNELRPCLVAELVGYRVTQIACGRWHTLAYVSDLGKVFSFGSGKDGQ 327
Query: 573 LGNNLGAHAQDKPKFVK 623
LGN G Q P VK
Sbjct: 328 LGNG-GTRDQLMPLPVK 343
Score = 64.9 bits (151), Expect = 3e-10
Identities = 36/100 (36%), Positives = 54/100 (54%), Gaps = 2/100 (2%)
Frame = +3
Query: 417 GRQTESDNG--KNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLG 590
G+ E DN K+ ++ I I CG HSLA+ + G+ F+WG + GQLG
Sbjct: 116 GKPFEYDNYSMKHLRFESILQEKKIIQITCGDYHSLALSKGGELFAWGQNLHGQLGVGRK 175
Query: 591 AHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
+ P+ V+ LA + Q++ G HS AL+ SG++YSW
Sbjct: 176 FPSTTTPQIVEHLAGVPLAQISAGEAHSTALSMSGNIYSW 215
>AF225407-1|AAO27483.1| 409|Homo sapiens HERC2 protein.
Length = 409
Score = 85.8 bits (203), Expect = 1e-16
Identities = 48/167 (28%), Positives = 88/167 (52%), Gaps = 2/167 (1%)
Frame = +3
Query: 216 MFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVA--AGEFHSLYLSNSGHLYS 389
++ WG + L G ++ +KP L + + + +A +G+ +L L++ ++S
Sbjct: 16 LYTWGKGRYGRL---GHSDSEDQLKPKLVEALQGHRVVDIACGSGDAQTLCLTDDDTVWS 72
Query: 390 CGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMG 569
G+ D G+LGR SD K P +++ + + CG Q S+A+ + G ++WG
Sbjct: 73 WGDGDYGKLGRGG-SDGCKVPMKIDSLTGLGVVKVECGSQFSVALTKSGAVYTWGKGDYH 131
Query: 570 QLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
+LG+ H + +P+ V+GL K VI +A G+ H V T G++Y+W
Sbjct: 132 RLGHGSDDHVR-RPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVYTW 177
Score = 75.4 bits (177), Expect = 2e-13
Identities = 45/127 (35%), Positives = 64/127 (50%), Gaps = 2/127 (1%)
Frame = +3
Query: 336 AAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGL--Q 509
AAG HS ++ +G LY+ G G+LG D K P LVE + + IACG
Sbjct: 1 AAGGAHSACVTAAGDLYTWGKGRYGRLGHSDSEDQLK-PKLVEALQGHRVVDIACGSGDA 59
Query: 510 HSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTN 689
+L + + +SWG G+LG G+ P + L V++V CG+ SVALT
Sbjct: 60 QTLCLTDDDTVWSWGDGDYGKLGRG-GSDGCKVPMKIDSLTGLGVVKVECGSQFSVALTK 118
Query: 690 SGDLYSW 710
SG +Y+W
Sbjct: 119 SGAVYTW 125
Score = 70.1 bits (164), Expect = 7e-12
Identities = 39/120 (32%), Positives = 65/120 (54%)
Frame = +3
Query: 333 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQH 512
V G S+ L+ SG +Y+ G D +LG ++ D+ + P V+ + + IA G H
Sbjct: 106 VECGSQFSVALTKSGAVYTWGKGDYHRLGHGSD-DHVRRPRQVQGLQGKKVIAIATGSLH 164
Query: 513 SLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNS 692
+ E G+ ++WG + GQLG+ +A +P+ V L K V +VACG+ H++A + S
Sbjct: 165 CVCCTEDGEVYTWGDNDEGQLGDGT-TNAIQRPRLVAALQGKKVNRVACGSAHTLAWSTS 223
Score = 57.2 bits (132), Expect = 5e-08
Identities = 31/102 (30%), Positives = 52/102 (50%)
Frame = +3
Query: 216 MFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCG 395
++ WG +H L G D V +P + + + A+A G H + + G +Y+ G
Sbjct: 122 VYTWGKGDYHRL---GHGSDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVYTWG 178
Query: 396 NNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLA 521
+ND GQLG T ++ + P LV + ++ +ACG H+LA
Sbjct: 179 DNDEGQLGDGT-TNAIQRPRLVAALQGKKVNRVACGSAHTLA 219
>AB046813-1|BAB13419.1| 953|Homo sapiens KIAA1593 protein protein.
Length = 953
Score = 85.8 bits (203), Expect = 1e-16
Identities = 57/172 (33%), Positives = 88/172 (51%), Gaps = 1/172 (0%)
Frame = +3
Query: 198 LQNYKKMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSG 377
L ++FCWG + +L + G+ P L K VAAG HS L+ SG
Sbjct: 48 LSKASEVFCWGQNKYGQLGL-GTDCKKQT-SPQLLKSLLGIPFMQVAAGGAHSFVLTLSG 105
Query: 378 HLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGS 557
++ G N GQLG E+D P L+++ + I I CG H+ A+ + G F++G+
Sbjct: 106 AIFGWGRNKFGQLGLNDENDRYV-PNLLKSLRSQKIVYICCGEDHTAALTKEGGVFTFGA 164
Query: 558 DSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA-LTNSGDLYSW 710
GQLG+N +H + P+ V L V ++ACG H+ A + +SG +YS+
Sbjct: 165 GGYGQLGHNSTSH-EINPRKVFELMGSIVTEIACGRQHTSAFVPSSGRIYSF 215
Score = 81.4 bits (192), Expect = 3e-15
Identities = 41/129 (31%), Positives = 66/129 (51%)
Frame = +3
Query: 324 IQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACG 503
I VA G +HSL LS + ++ G N GQLG T+ +P L+++ +A G
Sbjct: 35 IVQVACGYYHSLALSKASEVFCWGQNKYGQLGLGTDCKKQTSPQLLKSLLGIPFMQVAAG 94
Query: 504 LQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVAL 683
HS + G F WG + GQLG N + + P +K L ++ ++ + CG H+ AL
Sbjct: 95 GAHSFVLTLSGAIFGWGRNKFGQLGLN-DENDRYVPNLLKSLRSQKIVYICCGEDHTAAL 153
Query: 684 TNSGDLYSW 710
T G ++++
Sbjct: 154 TKEGGVFTF 162
Score = 67.7 bits (158), Expect = 4e-11
Identities = 31/84 (36%), Positives = 44/84 (52%)
Frame = +3
Query: 459 VETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATK 638
+++ D I +ACG HSLA+ + + F WG + GQLG Q P+ +K L
Sbjct: 27 IKSLSDIQIVQVACGYYHSLALSKASEVFCWGQNKYGQLGLGTDCKKQTSPQLLKSLLGI 86
Query: 639 NVIQVACGAYHSVALTNSGDLYSW 710
+QVA G HS LT SG ++ W
Sbjct: 87 PFMQVAAGGAHSFVLTLSGAIFGW 110
Score = 30.3 bits (65), Expect = 7.1
Identities = 18/48 (37%), Positives = 27/48 (56%), Gaps = 1/48 (2%)
Frame = +3
Query: 324 IQAVAAGEFH-SLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVE 464
+ +A G H S ++ +SG +YS G GQLG + S N K+P V+
Sbjct: 192 VTEIACGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTS-NRKSPFTVK 238
>AL356741-1|CAH74146.1| 907|Homo sapiens hect domain and RLD 4
protein.
Length = 907
Score = 85.4 bits (202), Expect = 2e-16
Identities = 56/171 (32%), Positives = 89/171 (52%), Gaps = 1/171 (0%)
Frame = +3
Query: 201 QNYKKMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGH 380
++ ++FCWG + +L + G+ P L K VAAG HS L+ SG
Sbjct: 3 ESASEVFCWGQNKYGQLGL-GTDCKKQT-SPQLLKSLLGIPFMQVAAGGAHSFVLTLSGA 60
Query: 381 LYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSD 560
++ G N GQLG E+D P L+++ + I I CG H+ A+ + G F++G+
Sbjct: 61 IFGWGRNKFGQLGLNDENDRYV-PNLLKSLRSQKIVYICCGEDHTAALTKEGGVFTFGAG 119
Query: 561 SMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA-LTNSGDLYSW 710
GQLG+N +H + P+ V L V ++ACG H+ A + +SG +YS+
Sbjct: 120 GYGQLGHNSTSH-EINPRKVFELMGSIVTEIACGRQHTSAFVPSSGRIYSF 169
Score = 30.3 bits (65), Expect = 7.1
Identities = 18/48 (37%), Positives = 27/48 (56%), Gaps = 1/48 (2%)
Frame = +3
Query: 324 IQAVAAGEFH-SLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVE 464
+ +A G H S ++ +SG +YS G GQLG + S N K+P V+
Sbjct: 146 VTEIACGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTS-NRKSPFTVK 192
>AL133551-1|CAI16031.1| 907|Homo sapiens hect domain and RLD 4
protein.
Length = 907
Score = 85.4 bits (202), Expect = 2e-16
Identities = 56/171 (32%), Positives = 89/171 (52%), Gaps = 1/171 (0%)
Frame = +3
Query: 201 QNYKKMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGH 380
++ ++FCWG + +L + G+ P L K VAAG HS L+ SG
Sbjct: 3 ESASEVFCWGQNKYGQLGL-GTDCKKQT-SPQLLKSLLGIPFMQVAAGGAHSFVLTLSGA 60
Query: 381 LYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSD 560
++ G N GQLG E+D P L+++ + I I CG H+ A+ + G F++G+
Sbjct: 61 IFGWGRNKFGQLGLNDENDRYV-PNLLKSLRSQKIVYICCGEDHTAALTKEGGVFTFGAG 119
Query: 561 SMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA-LTNSGDLYSW 710
GQLG+N +H + P+ V L V ++ACG H+ A + +SG +YS+
Sbjct: 120 GYGQLGHNSTSH-EINPRKVFELMGSIVTEIACGRQHTSAFVPSSGRIYSF 169
Score = 30.3 bits (65), Expect = 7.1
Identities = 18/48 (37%), Positives = 27/48 (56%), Gaps = 1/48 (2%)
Frame = +3
Query: 324 IQAVAAGEFH-SLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVE 464
+ +A G H S ++ +SG +YS G GQLG + S N K+P V+
Sbjct: 146 VTEIACGRQHTSAFVPSSGRIYSFGLGGNGQLGTGSTS-NRKSPFTVK 192
>BC029052-1|AAH29052.1| 551|Homo sapiens regulator of chromosome
condensation (RCC1) and BTB (POZ) domain containing pro
protein.
Length = 551
Score = 83.0 bits (196), Expect = 1e-15
Identities = 51/168 (30%), Positives = 88/168 (52%), Gaps = 2/168 (1%)
Frame = +3
Query: 213 KMFCWGNATHHELCIDGSQITDLVIKPT-LSKWKESDHIQAVAAGEFHSLYLSNSGHLYS 389
++F WG+ + +L G+ T+ + P +S + + VA G +HSL L++ G +++
Sbjct: 119 EVFTWGHNAYSQL---GNGTTNHGLVPCHISTNLSNKQVIEVACGSYHSLVLTSDGEVFA 175
Query: 390 CGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMG 569
G N+ GQ+G + + + ++ + TIACG +A+ + G+ + WG + G
Sbjct: 176 WGYNNSGQVGSGSTVNQPIPRRVTGCLQNKVVVTIACGQMCCMAVVDTGEVYVWGYNGNG 235
Query: 570 QLG-NNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
QLG N G Q P V L V +VACG H++ LT+ G +Y+W
Sbjct: 236 QLGLGNSG--NQPTPCRVAALQGIRVQRVACGYAHTLVLTDEGQVYAW 281
Score = 70.5 bits (165), Expect = 5e-12
Identities = 38/122 (31%), Positives = 68/122 (55%), Gaps = 2/122 (1%)
Frame = +3
Query: 351 HSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVET-FKDCTISTIACGLQHSLAID 527
H + + G +++ G+N QLG T +++G P + T + + +ACG HSL +
Sbjct: 110 HIVLATTEGEVFTWGHNAYSQLGNGT-TNHGLVPCHISTNLSNKQVIEVACGSYHSLVLT 168
Query: 528 EWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKG-LATKNVIQVACGAYHSVALTNSGDLY 704
G+ F+WG ++ GQ+G+ + Q P+ V G L K V+ +ACG +A+ ++G++Y
Sbjct: 169 SDGEVFAWGYNNSGQVGSGSTVN-QPIPRRVTGCLQNKVVVTIACGQMCCMAVVDTGEVY 227
Query: 705 SW 710
W
Sbjct: 228 VW 229
Score = 69.3 bits (162), Expect = 1e-11
Identities = 45/167 (26%), Positives = 80/167 (47%), Gaps = 1/167 (0%)
Frame = +3
Query: 213 KMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 392
++F WG ++ GS + + + ++ ++ + +A G+ + + ++G +Y
Sbjct: 172 EVFAWGYNNSGQVG-SGSTVNQPIPR-RVTGCLQNKVVVTIACGQMCCMAVVDTGEVYVW 229
Query: 393 GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQ 572
G N GQLG S N P V + + +ACG H+L + + GQ ++WG++S GQ
Sbjct: 230 GYNGNGQLGLGN-SGNQPTPCRVAALQGIRVQRVACGYAHTLVLTDEGQVYAWGANSYGQ 288
Query: 573 LGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH-SVALTNSGDLYSW 710
LG ++ Q P V + + AC + H S A T G +Y W
Sbjct: 289 LGTGNKSN-QSYPTPVTVEKDRIIEIAACHSTHTSAAKTQGGHVYMW 334
Score = 64.9 bits (151), Expect = 3e-10
Identities = 35/119 (29%), Positives = 61/119 (51%), Gaps = 1/119 (0%)
Frame = +3
Query: 357 LYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGL-QHSLAIDEW 533
LY + + ++ G N G LG + + P +++ I+ ++ G H +
Sbjct: 59 LYTTVNDEIFVLGTNCCGCLGLG-DVQSTIEPRRLDSLNGKKIACLSYGSGPHIVLATTE 117
Query: 534 GQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
G+ F+WG ++ QLGN H L+ K VI+VACG+YHS+ LT+ G++++W
Sbjct: 118 GEVFTWGHNAYSQLGNGTTNHGLVPCHISTNLSNKQVIEVACGSYHSLVLTSDGEVFAW 176
>AY341245-1|AAP88928.1| 551|Homo sapiens chromosome condensation
1-like protein.
Length = 551
Score = 83.0 bits (196), Expect = 1e-15
Identities = 51/168 (30%), Positives = 88/168 (52%), Gaps = 2/168 (1%)
Frame = +3
Query: 213 KMFCWGNATHHELCIDGSQITDLVIKPT-LSKWKESDHIQAVAAGEFHSLYLSNSGHLYS 389
++F WG+ + +L G+ T+ + P +S + + VA G +HSL L++ G +++
Sbjct: 119 EVFTWGHNAYSQL---GNGTTNHGLVPCHISTNLSNKQVIEVACGSYHSLVLTSDGEVFA 175
Query: 390 CGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMG 569
G N+ GQ+G + + + ++ + TIACG +A+ + G+ + WG + G
Sbjct: 176 WGYNNSGQVGSGSTVNQPIPRRVTGCLQNKVVVTIACGQMCCMAVVDTGEVYVWGYNGNG 235
Query: 570 QLG-NNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
QLG N G Q P V L V +VACG H++ LT+ G +Y+W
Sbjct: 236 QLGLGNSG--NQPTPCRVAALQGIRVQRVACGYAHTLVLTDEGQVYAW 281
Score = 70.5 bits (165), Expect = 5e-12
Identities = 38/122 (31%), Positives = 68/122 (55%), Gaps = 2/122 (1%)
Frame = +3
Query: 351 HSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVET-FKDCTISTIACGLQHSLAID 527
H + + G +++ G+N QLG T +++G P + T + + +ACG HSL +
Sbjct: 110 HIVLATTEGEVFTWGHNAYSQLGNGT-TNHGLVPCHISTNLSNKQVIEVACGSYHSLVLT 168
Query: 528 EWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKG-LATKNVIQVACGAYHSVALTNSGDLY 704
G+ F+WG ++ GQ+G+ + Q P+ V G L K V+ +ACG +A+ ++G++Y
Sbjct: 169 SDGEVFAWGYNNSGQVGSGSTVN-QPIPRRVTGCLQNKVVVTIACGQMCCMAVVDTGEVY 227
Query: 705 SW 710
W
Sbjct: 228 VW 229
Score = 69.3 bits (162), Expect = 1e-11
Identities = 45/167 (26%), Positives = 80/167 (47%), Gaps = 1/167 (0%)
Frame = +3
Query: 213 KMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 392
++F WG ++ GS + + + ++ ++ + +A G+ + + ++G +Y
Sbjct: 172 EVFAWGYNNSGQVG-SGSTVNQPIPR-RVTGCLQNKVVVTIACGQMCCMAVVDTGEVYVW 229
Query: 393 GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQ 572
G N GQLG S N P V + + +ACG H+L + + GQ ++WG++S GQ
Sbjct: 230 GYNGNGQLGLGN-SGNQPTPCRVAALQGIRVQRVACGYAHTLVLTDEGQVYAWGANSYGQ 288
Query: 573 LGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH-SVALTNSGDLYSW 710
LG ++ Q P V + + AC + H S A T G +Y W
Sbjct: 289 LGTGNKSN-QSYPTPVTVEKDRIIEIAACHSTHTSAAKTQGGHVYMW 334
Score = 64.9 bits (151), Expect = 3e-10
Identities = 35/119 (29%), Positives = 61/119 (51%), Gaps = 1/119 (0%)
Frame = +3
Query: 357 LYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGL-QHSLAIDEW 533
LY + + ++ G N G LG + + P +++ I+ ++ G H +
Sbjct: 59 LYTTVNDEIFVLGTNCCGCLGLG-DVQSTIEPRRLDSLNGKKIACLSYGSGPHIVLATTE 117
Query: 534 GQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
G+ F+WG ++ QLGN H L+ K VI+VACG+YHS+ LT+ G++++W
Sbjct: 118 GEVFTWGHNAYSQLGNGTTNHGLVPCHISTNLSNKQVIEVACGSYHSLVLTSDGEVFAW 176
>AL157813-1|CAH70795.1| 551|Homo sapiens regulator of chromosome
condensation (RCC1) and BTB (POZ) domain containing pro
protein.
Length = 551
Score = 83.0 bits (196), Expect = 1e-15
Identities = 51/168 (30%), Positives = 88/168 (52%), Gaps = 2/168 (1%)
Frame = +3
Query: 213 KMFCWGNATHHELCIDGSQITDLVIKPT-LSKWKESDHIQAVAAGEFHSLYLSNSGHLYS 389
++F WG+ + +L G+ T+ + P +S + + VA G +HSL L++ G +++
Sbjct: 119 EVFTWGHNAYSQL---GNGTTNHGLVPCHISTNLSNKQVIEVACGSYHSLVLTSDGEVFA 175
Query: 390 CGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMG 569
G N+ GQ+G + + + ++ + TIACG +A+ + G+ + WG + G
Sbjct: 176 WGYNNSGQVGSGSTVNQPIPRRVTGCLQNKVVVTIACGQMCCMAVVDTGEVYVWGYNGNG 235
Query: 570 QLG-NNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
QLG N G Q P V L V +VACG H++ LT+ G +Y+W
Sbjct: 236 QLGLGNSG--NQPTPCRVAALQGIRVQRVACGYAHTLVLTDEGQVYAW 281
Score = 70.5 bits (165), Expect = 5e-12
Identities = 38/122 (31%), Positives = 68/122 (55%), Gaps = 2/122 (1%)
Frame = +3
Query: 351 HSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVET-FKDCTISTIACGLQHSLAID 527
H + + G +++ G+N QLG T +++G P + T + + +ACG HSL +
Sbjct: 110 HIVLATTEGEVFTWGHNAYSQLGNGT-TNHGLVPCHISTNLSNKQVIEVACGSYHSLVLT 168
Query: 528 EWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKG-LATKNVIQVACGAYHSVALTNSGDLY 704
G+ F+WG ++ GQ+G+ + Q P+ V G L K V+ +ACG +A+ ++G++Y
Sbjct: 169 SDGEVFAWGYNNSGQVGSGSTVN-QPIPRRVTGCLQNKVVVTIACGQMCCMAVVDTGEVY 227
Query: 705 SW 710
W
Sbjct: 228 VW 229
Score = 69.3 bits (162), Expect = 1e-11
Identities = 45/167 (26%), Positives = 80/167 (47%), Gaps = 1/167 (0%)
Frame = +3
Query: 213 KMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 392
++F WG ++ GS + + + ++ ++ + +A G+ + + ++G +Y
Sbjct: 172 EVFAWGYNNSGQVG-SGSTVNQPIPR-RVTGCLQNKVVVTIACGQMCCMAVVDTGEVYVW 229
Query: 393 GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQ 572
G N GQLG S N P V + + +ACG H+L + + GQ ++WG++S GQ
Sbjct: 230 GYNGNGQLGLGN-SGNQPTPCRVAALQGIRVQRVACGYAHTLVLTDEGQVYAWGANSYGQ 288
Query: 573 LGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH-SVALTNSGDLYSW 710
LG ++ Q P V + + AC + H S A T G +Y W
Sbjct: 289 LGTGNKSN-QSYPTPVTVEKDRIIEIAACHSTHTSAAKTQGGHVYMW 334
Score = 64.9 bits (151), Expect = 3e-10
Identities = 35/119 (29%), Positives = 61/119 (51%), Gaps = 1/119 (0%)
Frame = +3
Query: 357 LYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGL-QHSLAIDEW 533
LY + + ++ G N G LG + + P +++ I+ ++ G H +
Sbjct: 59 LYTTVNDEIFVLGTNCCGCLGLG-DVQSTIEPRRLDSLNGKKIACLSYGSGPHIVLATTE 117
Query: 534 GQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
G+ F+WG ++ QLGN H L+ K VI+VACG+YHS+ LT+ G++++W
Sbjct: 118 GEVFTWGHNAYSQLGNGTTNHGLVPCHISTNLSNKQVIEVACGSYHSLVLTSDGEVFAW 176
>AK092403-1|BAC03879.1| 184|Homo sapiens protein ( Homo sapiens
cDNA FLJ35084 fis, clone PLACE6005482. ).
Length = 184
Score = 83.0 bits (196), Expect = 1e-15
Identities = 44/129 (34%), Positives = 68/129 (52%), Gaps = 3/129 (2%)
Frame = +3
Query: 333 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQH 512
V+ G +HSL LS ++S G N GQLG E + +P V + + ++ +A G H
Sbjct: 11 VSCGHYHSLALSKDSQVFSWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPLAQVAAGGAH 70
Query: 513 SLAIDEWGQPFSWGSDSMGQL---GNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVAL 683
S A+ G F WGS+S GQL G N+ + +KP V L V+ ++CG H+ L
Sbjct: 71 SFALSLCGTSFGWGSNSAGQLALSGRNVPVQS-NKPLSVGALKNLGVVYISCGDAHTAVL 129
Query: 684 TNSGDLYSW 710
T G ++++
Sbjct: 130 TQDGKVFTF 138
Score = 63.7 bits (148), Expect = 6e-10
Identities = 33/82 (40%), Positives = 44/82 (53%)
Frame = +3
Query: 465 TFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNV 644
T D I ++CG HSLA+ + Q FSWG +S GQLG +Q P+ V+ L +
Sbjct: 2 TLNDIKIIQVSCGHYHSLALSKDSQVFSWGKNSHGQLGLGKEFPSQASPQRVRSLEGIPL 61
Query: 645 IQVACGAYHSVALTNSGDLYSW 710
QVA G HS AL+ G + W
Sbjct: 62 AQVAAGGAHSFALSLCGTSFGW 83
Score = 57.6 bits (133), Expect = 4e-08
Identities = 40/130 (30%), Positives = 61/130 (46%), Gaps = 3/130 (2%)
Frame = +3
Query: 198 LQNYKKMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSG 377
L ++F WG +H +L + G + P + E + VAAG HS LS G
Sbjct: 21 LSKDSQVFSWGKNSHGQLGL-GKEFPSQA-SPQRVRSLEGIPLAQVAAGGAHSFALSLCG 78
Query: 378 HLYSCGNNDVGQL---GRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFS 548
+ G+N GQL GR + K P V K+ + I+CG H+ + + G+ F+
Sbjct: 79 TSFGWGSNSAGQLALSGRNVPVQSNK-PLSVGALKNLGVVYISCGDAHTAVLTQDGKVFT 137
Query: 549 WGSDSMGQLG 578
+G + GQLG
Sbjct: 138 FGDNRSGQLG 147
>AF060219-1|AAC79987.1| 551|Homo sapiens RCC1-like G exchanging
factor RLG protein.
Length = 551
Score = 83.0 bits (196), Expect = 1e-15
Identities = 51/168 (30%), Positives = 88/168 (52%), Gaps = 2/168 (1%)
Frame = +3
Query: 213 KMFCWGNATHHELCIDGSQITDLVIKPT-LSKWKESDHIQAVAAGEFHSLYLSNSGHLYS 389
++F WG+ + +L G+ T+ + P +S + + VA G +HSL L++ G +++
Sbjct: 119 EVFTWGHNAYSQL---GNGTTNHGLVPCHISTNLSNKQVIEVACGSYHSLVLTSDGEVFA 175
Query: 390 CGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMG 569
G N+ GQ+G + + + ++ + TIACG +A+ + G+ + WG + G
Sbjct: 176 WGYNNSGQVGSGSTVNQPIPRRVTGCLQNKVVVTIACGQMCCMAVVDTGEVYVWGYNGNG 235
Query: 570 QLG-NNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
QLG N G Q P V L V +VACG H++ LT+ G +Y+W
Sbjct: 236 QLGLGNSG--NQPTPCRVAALQGIRVQRVACGYAHTLVLTDEGQVYAW 281
Score = 70.5 bits (165), Expect = 5e-12
Identities = 38/122 (31%), Positives = 68/122 (55%), Gaps = 2/122 (1%)
Frame = +3
Query: 351 HSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVET-FKDCTISTIACGLQHSLAID 527
H + + G +++ G+N QLG T +++G P + T + + +ACG HSL +
Sbjct: 110 HIVLATTEGEVFTWGHNAYSQLGNGT-TNHGLVPCHISTNLSNKQVIEVACGSYHSLVLT 168
Query: 528 EWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKG-LATKNVIQVACGAYHSVALTNSGDLY 704
G+ F+WG ++ GQ+G+ + Q P+ V G L K V+ +ACG +A+ ++G++Y
Sbjct: 169 SDGEVFAWGYNNSGQVGSGSTVN-QPIPRRVTGCLQNKVVVTIACGQMCCMAVVDTGEVY 227
Query: 705 SW 710
W
Sbjct: 228 VW 229
Score = 69.3 bits (162), Expect = 1e-11
Identities = 45/167 (26%), Positives = 80/167 (47%), Gaps = 1/167 (0%)
Frame = +3
Query: 213 KMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 392
++F WG ++ GS + + + ++ ++ + +A G+ + + ++G +Y
Sbjct: 172 EVFAWGYNNSGQVG-SGSTVNQPIPR-RVTGCLQNKVVVTIACGQMCCMAVVDTGEVYVW 229
Query: 393 GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQ 572
G N GQLG S N P V + + +ACG H+L + + GQ ++WG++S GQ
Sbjct: 230 GYNGNGQLGLGN-SGNQPTPCRVAALQGIRVQRVACGYAHTLVLTDEGQVYAWGANSYGQ 288
Query: 573 LGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH-SVALTNSGDLYSW 710
LG ++ Q P V + + AC + H S A T G +Y W
Sbjct: 289 LGTGNKSN-QSYPTPVTVEKDRIIEIAACHSTHTSAAKTQGGHVYMW 334
Score = 64.9 bits (151), Expect = 3e-10
Identities = 35/119 (29%), Positives = 61/119 (51%), Gaps = 1/119 (0%)
Frame = +3
Query: 357 LYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGL-QHSLAIDEW 533
LY + + ++ G N G LG + + P +++ I+ ++ G H +
Sbjct: 59 LYTTVNDEIFVLGTNCCGCLGLG-DVQSTIEPRRLDSLNGKKIACLSYGSGPHIVLATTE 117
Query: 534 GQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
G+ F+WG ++ QLGN H L+ K VI+VACG+YHS+ LT+ G++++W
Sbjct: 118 GEVFTWGHNAYSQLGNGTTNHGLVPCHISTNLSNKQVIEVACGSYHSLVLTSDGEVFAW 176
>AB209543-1|BAD92780.1| 556|Homo sapiens RCC1-like G exchanging
factor RLG variant protein.
Length = 556
Score = 83.0 bits (196), Expect = 1e-15
Identities = 51/168 (30%), Positives = 88/168 (52%), Gaps = 2/168 (1%)
Frame = +3
Query: 213 KMFCWGNATHHELCIDGSQITDLVIKPT-LSKWKESDHIQAVAAGEFHSLYLSNSGHLYS 389
++F WG+ + +L G+ T+ + P +S + + VA G +HSL L++ G +++
Sbjct: 124 EVFTWGHNAYSQL---GNGTTNHGLVPCHISTNLSNKQVIEVACGSYHSLVLTSDGEVFA 180
Query: 390 CGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMG 569
G N+ GQ+G + + + ++ + TIACG +A+ + G+ + WG + G
Sbjct: 181 WGYNNSGQVGSGSTVNQPIPRRVTGCLQNKVVVTIACGQMCCMAVVDTGEVYVWGYNGNG 240
Query: 570 QLG-NNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
QLG N G Q P V L V +VACG H++ LT+ G +Y+W
Sbjct: 241 QLGLGNSG--NQPTPCRVAALQGIRVQRVACGYAHTLVLTDEGQVYAW 286
Score = 70.5 bits (165), Expect = 5e-12
Identities = 38/122 (31%), Positives = 68/122 (55%), Gaps = 2/122 (1%)
Frame = +3
Query: 351 HSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVET-FKDCTISTIACGLQHSLAID 527
H + + G +++ G+N QLG T +++G P + T + + +ACG HSL +
Sbjct: 115 HIVLATTEGEVFTWGHNAYSQLGNGT-TNHGLVPCHISTNLSNKQVIEVACGSYHSLVLT 173
Query: 528 EWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKG-LATKNVIQVACGAYHSVALTNSGDLY 704
G+ F+WG ++ GQ+G+ + Q P+ V G L K V+ +ACG +A+ ++G++Y
Sbjct: 174 SDGEVFAWGYNNSGQVGSGSTVN-QPIPRRVTGCLQNKVVVTIACGQMCCMAVVDTGEVY 232
Query: 705 SW 710
W
Sbjct: 233 VW 234
Score = 69.3 bits (162), Expect = 1e-11
Identities = 45/167 (26%), Positives = 80/167 (47%), Gaps = 1/167 (0%)
Frame = +3
Query: 213 KMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 392
++F WG ++ GS + + + ++ ++ + +A G+ + + ++G +Y
Sbjct: 177 EVFAWGYNNSGQVG-SGSTVNQPIPR-RVTGCLQNKVVVTIACGQMCCMAVVDTGEVYVW 234
Query: 393 GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQ 572
G N GQLG S N P V + + +ACG H+L + + GQ ++WG++S GQ
Sbjct: 235 GYNGNGQLGLGN-SGNQPTPCRVAALQGIRVQRVACGYAHTLVLTDEGQVYAWGANSYGQ 293
Query: 573 LGNNLGAHAQDKPKFVKGLATKNVIQVACGAYH-SVALTNSGDLYSW 710
LG ++ Q P V + + AC + H S A T G +Y W
Sbjct: 294 LGTGNKSN-QSYPTPVTVEKDRIIEIAACHSTHTSAAKTQGGHVYMW 339
Score = 64.9 bits (151), Expect = 3e-10
Identities = 35/119 (29%), Positives = 61/119 (51%), Gaps = 1/119 (0%)
Frame = +3
Query: 357 LYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGL-QHSLAIDEW 533
LY + + ++ G N G LG + + P +++ I+ ++ G H +
Sbjct: 64 LYTTVNDEIFVLGTNCCGCLGLG-DVQSTIEPRRLDSLNGKKIACLSYGSGPHIVLATTE 122
Query: 534 GQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
G+ F+WG ++ QLGN H L+ K VI+VACG+YHS+ LT+ G++++W
Sbjct: 123 GEVFTWGHNAYSQLGNGTTNHGLVPCHISTNLSNKQVIEVACGSYHSLVLTSDGEVFAW 181
>U50078-1|AAD12586.1| 4861|Homo sapiens p532 protein.
Length = 4861
Score = 80.6 bits (190), Expect = 5e-15
Identities = 51/169 (30%), Positives = 90/169 (53%), Gaps = 3/169 (1%)
Frame = +3
Query: 213 KMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 392
+++ WG+ + H+L ++G+Q + +++P L+ SD Q + AG++ + +S G + +C
Sbjct: 373 EVYVWGSNSSHQL-VEGTQ--EKILQPKLAP-SFSD-AQTIEAGQYCTFVISTDGSVRAC 427
Query: 393 GNNDVGQLGRQTESDNGKNPALV-ETFKDCTISTIACGLQ-HSLAIDEWGQPFSWGSDSM 566
G G+LG ++ L E + + + G H+LA G+ FSWG
Sbjct: 428 GKGSYGRLGLGDSNNQSTLKKLTFEPHRSIKKVSSSKGSDGHTLAFTTEGEVFSWGDGDY 487
Query: 567 GQLGNNLGAHAQDKPKFVKG-LATKNVIQVACGAYHSVALTNSGDLYSW 710
G+LG+ + Q PK ++G L K V+ V+ G HS A+T G+LY+W
Sbjct: 488 GKLGHG-NSSTQKYPKLIQGPLQGKVVVCVSAGYRHSAAVTEDGELYTW 535
Score = 77.4 bits (182), Expect = 5e-14
Identities = 45/168 (26%), Positives = 85/168 (50%), Gaps = 3/168 (1%)
Frame = +3
Query: 216 MFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCG 395
++ WG H +L G + P+ S+ Q V G+ + + +G + +CG
Sbjct: 3999 VYLWGAGRHGQLAEAGRNVMVPAAAPSFSQ------AQQVICGQNCTFVIQANGTVLACG 4052
Query: 396 NNDVGQLGRQTESDNGKNPALVETFKDCTISTI--ACGLQ-HSLAIDEWGQPFSWGSDSM 566
G+LG Q SD+ ++ + ++ + +CG HS+A+ E G+ FSWG
Sbjct: 4053 EGSYGRLG-QGNSDDLHVLTVISALQGFVVTQLVTSCGSDGHSMALTESGEVFSWGDGDY 4111
Query: 567 GQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
G+LG+ + Q +P+ ++ L + V+Q++CG HS +T+ G L+++
Sbjct: 4112 GKLGHG-NSDRQRRPRQIEALQGEEVVQMSCGFKHSAVVTSDGKLFTF 4158
Score = 73.3 bits (172), Expect = 8e-13
Identities = 41/157 (26%), Positives = 81/157 (51%), Gaps = 1/157 (0%)
Frame = +3
Query: 228 GNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDV 407
G ++ L + S + K T + + + + H+L + G ++S G+ D
Sbjct: 428 GKGSYGRLGLGDSNNQSTLKKLTFEPHRSIKKVSSSKGSDGHTLAFTTEGEVFSWGDGDY 487
Query: 408 GQLGRQTESDNGKNPALVE-TFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNN 584
G+LG S K P L++ + + ++ G +HS A+ E G+ ++WG G+LG+
Sbjct: 488 GKLGHGNSSTQ-KYPKLIQGPLQGKVVVCVSAGYRHSAAVTEDGELYTWGEGDFGRLGHG 546
Query: 585 LGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSG 695
+++++ P VK ++ NV +V+CG+ H++AL+ G
Sbjct: 547 -DSNSRNIPTLVKDIS--NVGEVSCGSSHTIALSKDG 580
Score = 72.9 bits (171), Expect = 1e-12
Identities = 45/167 (26%), Positives = 82/167 (49%), Gaps = 1/167 (0%)
Frame = +3
Query: 213 KMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGH-LYS 389
+++ WG L S ++ PTL K + ++ V+ G H++ LS G ++S
Sbjct: 531 ELYTWGEGDFGRLGHGDSNSRNI---PTLVK--DISNVGEVSCGSSHTIALSKDGRTVWS 585
Query: 390 CGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMG 569
G D G+LG +++ P ++E + I + G Q SLA+ GQ ++WG +
Sbjct: 586 FGGGDNGKLGHG-DTNRVYKPKVIEALQGMFIRKVCAGSQSSLALTSTGQVYAWGCGAC- 643
Query: 570 QLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
LG +PK ++ LA ++ V+ G H +AL++ ++Y+W
Sbjct: 644 -LGCGSSEATALRPKLIEELAATRIVDVSIGDSHCLALSHDNEVYAW 689
Score = 72.1 bits (169), Expect = 2e-12
Identities = 42/121 (34%), Positives = 63/121 (52%)
Frame = +3
Query: 324 IQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACG 503
I+ VA G S+ L+ GH+Y+ G + + L + + N P + I +A G
Sbjct: 4241 IKKVACGTQFSVALTKDGHVYTFGQDRLIGLP-EGRARNHNRPQQIPVLAGVIIEDVAVG 4299
Query: 504 LQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVAL 683
+H+LA+ G ++WGS+S GQLG H ++ P V GL KNV Q++ G HS A
Sbjct: 4300 AEHTLALASNGDVYAWGSNSEGQLGLGHTNHVRE-PTLVTGLQGKNVRQISAGRCHSAAW 4358
Query: 684 T 686
T
Sbjct: 4359 T 4359
Score = 71.3 bits (167), Expect = 3e-12
Identities = 39/118 (33%), Positives = 66/118 (55%), Gaps = 1/118 (0%)
Frame = +3
Query: 351 HSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDE 530
HS+ L+ SG ++S G+ D G+LG SD + P +E + + ++CG +HS +
Sbjct: 4093 HSMALTESGEVFSWGDGDYGKLGHGN-SDRQRRPRQIEALQGEEVVQMSCGFKHSAVVTS 4151
Query: 531 WGQPFSWGSDSMGQLGNNLGAHAQDK-PKFVKGLATKNVIQVACGAYHSVALTNSGDL 701
G+ F++G+ G+LG LG + K P+ V L + QVACG H++A++ G +
Sbjct: 4152 DGKLFTFGNGDYGRLG--LGNTSNKKLPERVTALEGYQIGQVACGLNHTLAVSADGSM 4207
Score = 69.7 bits (163), Expect = 9e-12
Identities = 48/167 (28%), Positives = 84/167 (50%), Gaps = 1/167 (0%)
Frame = +3
Query: 213 KMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHL-YS 389
K+F +GN + L + + L + T E I VA G H+L +S G + ++
Sbjct: 4154 KLFTFGNGDYGRLGLGNTSNKKLPERVTAL---EGYQIGQVACGLNHTLAVSADGSMVWA 4210
Query: 390 CGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMG 569
G+ D G+LG + +P ++ I +ACG Q S+A+ + G +++G D +
Sbjct: 4211 FGDGDYGKLGLGNSTAKS-SPQKIDVLCGIGIKKVACGTQFSVALTKDGHVYTFGQDRLI 4269
Query: 570 QLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
L A ++P+ + LA + VA GA H++AL ++GD+Y+W
Sbjct: 4270 GLPEGR-ARNHNRPQQIPVLAGVIIEDVAVGAEHTLALASNGDVYAW 4315
Score = 68.9 bits (161), Expect = 2e-11
Identities = 43/138 (31%), Positives = 67/138 (48%)
Frame = +3
Query: 273 TDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNP 452
T+ V KP + + + I+ V AG SL L+++G +Y+ G LG + P
Sbjct: 599 TNRVYKPKVIEALQGMFIRKVCAGSQSSLALTSTGQVYAWGCGAC--LGCGSSEATALRP 656
Query: 453 ALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLA 632
L+E I ++ G H LA+ + ++WG++SMGQ G KPK V GL
Sbjct: 657 KLIEELAATRIVDVSIGDSHCLALSHDNEVYAWGNNSMGQCGQGNSTGPITKPKKVSGLD 716
Query: 633 TKNVIQVACGAYHSVALT 686
+ Q++ G HS+A T
Sbjct: 717 GIAIQQISAGTSHSLAWT 734
Score = 47.6 bits (108), Expect = 4e-05
Identities = 28/103 (27%), Positives = 45/103 (43%)
Frame = +3
Query: 213 KMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 392
+++ WG C+ ++P L + + I V+ G+ H L LS+ +Y+
Sbjct: 634 QVYAWGCGA----CLGCGSSEATALRPKLIEELAATRIVDVSIGDSHCLALSHDNEVYAW 689
Query: 393 GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLA 521
GNN +GQ G+ + P V I I+ G HSLA
Sbjct: 690 GNNSMGQCGQGNSTGPITKPKKVSGLDGIAIQQISAGTSHSLA 732
>BC065375-1|AAH65375.1| 458|Homo sapiens secretion regulating
guanine nucleotide exchange factor protein.
Length = 458
Score = 79.4 bits (187), Expect = 1e-14
Identities = 50/166 (30%), Positives = 85/166 (51%), Gaps = 1/166 (0%)
Frame = +3
Query: 216 MFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCG 395
+F WG ++ +L + + D+++ L+ + + ++ + G HS +++ G L+ CG
Sbjct: 17 LFAWGANSYGQLGLGHKE--DVLLPQQLNDFCKPRSVRRITGGGGHSAVVTDGGDLFVCG 74
Query: 396 NNDVGQLGR-QTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQ 572
N GQLG TE P ++ C I +ACG ++ + E GQ S GS+S GQ
Sbjct: 75 LNKDGQLGLGHTEDIPYFTPC--KSLFGCPIQQVACGWDFTIMLTENGQVLSCGSNSFGQ 132
Query: 573 LGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
LG G P+ ++ L + V+ +A G H+VA T SG ++ W
Sbjct: 133 LGVPHGPRRCVVPQAIE-LHKEKVVCIAAGLRHAVAATASGIVFQW 177
Score = 64.1 bits (149), Expect = 5e-10
Identities = 48/185 (25%), Positives = 91/185 (49%), Gaps = 15/185 (8%)
Frame = +3
Query: 174 ANSSY*KKLQNYKKMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFH 353
A S + L + +++ WG+ H +L + + + V + + +++ + A+ +G H
Sbjct: 219 AGSDHSASLTDAGEVYVWGSNKHGQLANEAAFLP--VPQKIEAHCFQNEKVTAIWSGWTH 276
Query: 354 SLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCT---------------IS 488
+ + +G +++ G D GQLGR+ E+ G ++F C+ +
Sbjct: 277 LVAQTETGKMFTWGRADYGQLGRKLETYEGWKLEKQDSFLPCSRPPNSMPSSPHCLTGAT 336
Query: 489 TIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAY 668
++CG +H+LAI G +SWG + G G+ A+ PK V+ L + + + V CGA
Sbjct: 337 EVSCGSEHNLAIIG-GVCYSWGWNEHGMCGDGTEANVW-APKPVQALLSSSGLLVGCGAG 394
Query: 669 HSVAL 683
HS+AL
Sbjct: 395 HSLAL 399
Score = 53.6 bits (123), Expect = 7e-07
Identities = 41/148 (27%), Positives = 64/148 (43%), Gaps = 15/148 (10%)
Frame = +3
Query: 312 ESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTIST 491
E+ V AG HS L+++G +Y G+N GQL + F++ ++
Sbjct: 210 ENSKAMCVLAGSDHSASLTDAGEVYVWGSNKHGQLANEAAFLPVPQKIEAHCFQNEKVTA 269
Query: 492 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNL----GAHAQDKPKFVKGLATKN------ 641
I G H +A E G+ F+WG GQLG L G + + F+ N
Sbjct: 270 IWSGWTHLVAQTETGKMFTWGRADYGQLGRKLETYEGWKLEKQDSFLPCSRPPNSMPSSP 329
Query: 642 -----VIQVACGAYHSVALTNSGDLYSW 710
+V+CG+ H++A+ G YSW
Sbjct: 330 HCLTGATEVSCGSEHNLAII-GGVCYSW 356
Score = 45.2 bits (102), Expect = 2e-04
Identities = 31/138 (22%), Positives = 58/138 (42%), Gaps = 7/138 (5%)
Frame = +3
Query: 318 DHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDN-------GKNPALVETFKD 476
+ + +AAG H++ + SG ++ G + GR+ K P+ V ++
Sbjct: 153 EKVVCIAAGLRHAVAATASGIVFQWGTG-LASCGRRLCPGQTLPLFFTAKEPSRVTGLEN 211
Query: 477 CTISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVA 656
+ G HS ++ + G+ + WGS+ GQL N + + V +
Sbjct: 212 SKAMCVLAGSDHSASLTDAGEVYVWGSNKHGQLANEAAFLPVPQKIEAHCFQNEKVTAIW 271
Query: 657 CGAYHSVALTNSGDLYSW 710
G H VA T +G +++W
Sbjct: 272 SGWTHLVAQTETGKMFTW 289
>AJ243951-1|CAB60833.1| 288|Homo sapiens deafness locus associated
putative guanine nucleotide exchange factor protein.
Length = 288
Score = 79.4 bits (187), Expect = 1e-14
Identities = 50/166 (30%), Positives = 85/166 (51%), Gaps = 1/166 (0%)
Frame = +3
Query: 216 MFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCG 395
+F WG ++ +L + + D+++ L+ + + ++ + G HS +++ G L+ CG
Sbjct: 17 LFAWGANSYGQLGLGHKE--DVLLPQQLNDFCKPRSVRRITGGGGHSAVVTDGGDLFVCG 74
Query: 396 NNDVGQLGR-QTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQ 572
N GQLG TE P ++ C I +ACG ++ + E GQ S GS+S GQ
Sbjct: 75 LNKDGQLGLGHTEDIPYFTPC--KSLFGCPIQQVACGWDFTIMLTENGQVLSCGSNSFGQ 132
Query: 573 LGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
LG G P+ ++ L + V+ +A G H+VA T SG ++ W
Sbjct: 133 LGVPHGPRRCVVPQAIE-LHKEKVVCIAAGLRHAVAATASGIVFQW 177
Score = 67.7 bits (158), Expect = 4e-11
Identities = 46/135 (34%), Positives = 67/135 (49%), Gaps = 6/135 (4%)
Frame = +3
Query: 324 IQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACG 503
IQ VA G ++ L+ +G + SCG+N GQLG P +E K+ + IA G
Sbjct: 103 IQQVACGWDFTIMLTENGQVLSCGSNSFGQLGVPHGPRRCVVPQAIELHKEKVVC-IAAG 161
Query: 504 LQHSLAIDEWGQPFSWGSD--SMGQL---GNNLGAHAQDK-PKFVKGLATKNVIQVACGA 665
L+H++A G F WG+ S G+ G L K P V GL + V G+
Sbjct: 162 LRHAVAATASGIVFQWGTGLASCGRRLCPGQTLPLFFTAKEPSRVTGLENSKAMCVLAGS 221
Query: 666 YHSVALTNSGDLYSW 710
HS +LT++G++Y W
Sbjct: 222 DHSASLTDAGEVYVW 236
Score = 36.3 bits (80), Expect = 0.11
Identities = 23/95 (24%), Positives = 43/95 (45%), Gaps = 7/95 (7%)
Frame = +3
Query: 318 DHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDN-------GKNPALVETFKD 476
+ + +AAG H++ + SG ++ G + GR+ K P+ V ++
Sbjct: 153 EKVVCIAAGLRHAVAATASGIVFQWGTG-LASCGRRLCPGQTLPLFFTAKEPSRVTGLEN 211
Query: 477 CTISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGN 581
+ G HS ++ + G+ + WGS+ GQL N
Sbjct: 212 SKAMCVLAGSDHSASLTDAGEVYVWGSNKHGQLAN 246
Score = 31.5 bits (68), Expect = 3.1
Identities = 19/70 (27%), Positives = 31/70 (44%)
Frame = +3
Query: 312 ESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTIST 491
E+ V AG HS L+++G +Y G+N GQL + F++ ++
Sbjct: 210 ENSKAMCVLAGSDHSASLTDAGEVYVWGSNKHGQLANEAAFLPVPQKIEAHCFQNEKVTA 269
Query: 492 IACGLQHSLA 521
I G H +A
Sbjct: 270 IWSGWTHLVA 279
>AJ243950-1|CAB60832.1| 458|Homo sapiens deafness locus associated
putative guanine nucleotide exchange factor protein.
Length = 458
Score = 79.4 bits (187), Expect = 1e-14
Identities = 50/166 (30%), Positives = 85/166 (51%), Gaps = 1/166 (0%)
Frame = +3
Query: 216 MFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCG 395
+F WG ++ +L + + D+++ L+ + + ++ + G HS +++ G L+ CG
Sbjct: 17 LFAWGANSYGQLGLGHKE--DVLLPQQLNDFCKPRSVRRITGGGGHSAVVTDGGDLFVCG 74
Query: 396 NNDVGQLGR-QTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQ 572
N GQLG TE P ++ C I +ACG ++ + E GQ S GS+S GQ
Sbjct: 75 LNKDGQLGLGHTEDIPYFTPC--KSLFGCPIQQVACGWDFTIMLTENGQVLSCGSNSFGQ 132
Query: 573 LGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
LG G P+ ++ L + V+ +A G H+VA T SG ++ W
Sbjct: 133 LGVPHGPRRCVVPQAIE-LHKEKVVCIAAGLRHAVAATASGIVFQW 177
Score = 64.1 bits (149), Expect = 5e-10
Identities = 48/185 (25%), Positives = 91/185 (49%), Gaps = 15/185 (8%)
Frame = +3
Query: 174 ANSSY*KKLQNYKKMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFH 353
A S + L + +++ WG+ H +L + + + V + + +++ + A+ +G H
Sbjct: 219 AGSDHSASLTDAGEVYVWGSNKHGQLANEAAFLP--VPQKIEAHCFQNEKVTAIWSGWTH 276
Query: 354 SLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCT---------------IS 488
+ + +G +++ G D GQLGR+ E+ G ++F C+ +
Sbjct: 277 LVAQTETGKMFTWGRADYGQLGRKLETYEGWKLEKQDSFLPCSRPPNSMPSSPHCLTGAT 336
Query: 489 TIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAY 668
++CG +H+LAI G +SWG + G G+ A+ PK V+ L + + + V CGA
Sbjct: 337 EVSCGSEHNLAIIG-GVCYSWGWNEHGMCGDGTEANVW-APKPVQALLSSSGLLVGCGAG 394
Query: 669 HSVAL 683
HS+AL
Sbjct: 395 HSLAL 399
Score = 53.6 bits (123), Expect = 7e-07
Identities = 41/148 (27%), Positives = 64/148 (43%), Gaps = 15/148 (10%)
Frame = +3
Query: 312 ESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTIST 491
E+ V AG HS L+++G +Y G+N GQL + F++ ++
Sbjct: 210 ENSKAMCVLAGSDHSASLTDAGEVYVWGSNKHGQLANEAAFLPVPQKIEAHCFQNEKVTA 269
Query: 492 IACGLQHSLAIDEWGQPFSWGSDSMGQLGNNL----GAHAQDKPKFVKGLATKN------ 641
I G H +A E G+ F+WG GQLG L G + + F+ N
Sbjct: 270 IWSGWTHLVAQTETGKMFTWGRADYGQLGRKLETYEGWKLEKQDSFLPCSRPPNSMPSSP 329
Query: 642 -----VIQVACGAYHSVALTNSGDLYSW 710
+V+CG+ H++A+ G YSW
Sbjct: 330 HCLTGATEVSCGSEHNLAII-GGVCYSW 356
Score = 45.2 bits (102), Expect = 2e-04
Identities = 31/138 (22%), Positives = 58/138 (42%), Gaps = 7/138 (5%)
Frame = +3
Query: 318 DHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDN-------GKNPALVETFKD 476
+ + +AAG H++ + SG ++ G + GR+ K P+ V ++
Sbjct: 153 EKVVCIAAGLRHAVAATASGIVFQWGTG-LASCGRRLCPGQTLPLFFTAKEPSRVTGLEN 211
Query: 477 CTISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVA 656
+ G HS ++ + G+ + WGS+ GQL N + + V +
Sbjct: 212 SKAMCVLAGSDHSASLTDAGEVYVWGSNKHGQLANEAAFLPVPQKIEAHCFQNEKVTAIW 271
Query: 657 CGAYHSVALTNSGDLYSW 710
G H VA T +G +++W
Sbjct: 272 SGWTHLVAQTETGKMFTW 289
>AC004460-2|AAC06339.1| 371|Homo sapiens WUGSC:H_DJ1086D14.2
protein.
Length = 371
Score = 76.2 bits (179), Expect = 1e-13
Identities = 48/157 (30%), Positives = 80/157 (50%)
Frame = +3
Query: 216 MFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCG 395
+F WG+ +L GS+ ++ P + + + G L L+ SG +++ G
Sbjct: 3 VFSWGDGDFGKLGRGGSEGCNI---PQNIERLNGQGVCQIECGAQFLLALTKSGVVWTWG 59
Query: 396 NNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQL 575
D +LG +++ + + P +VE + I +A G QH LA+ + GQ ++WG + GQ
Sbjct: 60 KGDYFRLGHRSDV-HVRKPQVVEGLRGKKIVHVAVGAQHCLAVMDSGQVYAWGDNDHGQQ 118
Query: 576 GNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALT 686
GN KP V+GL + ++ VACG+ HSVA T
Sbjct: 119 GNGT-TTVNRKPMLVQGLEGQKIMCVACGSSHSVAWT 154
Score = 74.9 bits (176), Expect = 3e-13
Identities = 39/112 (34%), Positives = 62/112 (55%)
Frame = +3
Query: 375 GHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWG 554
G ++S G+ D G+LGR S+ P +E + I CG Q LA+ + G ++WG
Sbjct: 1 GLVFSWGDGDFGKLGRGG-SEGCNIPQNIERLNGQGVCQIECGAQFLLALTKSGVVWTWG 59
Query: 555 SDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
+LG+ H + KP+ V+GL K ++ VA GA H +A+ +SG +Y+W
Sbjct: 60 KGDYFRLGHRSDVHVR-KPQVVEGLRGKKIVHVAVGAQHCLAVMDSGQVYAW 110
>AL139321-5|CAH71047.1| 531|Homo sapiens regulator of chromosome
condensation (RCC1) and BTB (POZ) domain containing pro
protein.
Length = 531
Score = 74.5 bits (175), Expect = 3e-13
Identities = 50/167 (29%), Positives = 84/167 (50%), Gaps = 2/167 (1%)
Frame = +3
Query: 216 MFCWGNATHHELCIDGSQITDLVIKPT-LSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 392
++ WG+ + +L G+ T+ I P + + VA G HS+ L+ G +++
Sbjct: 96 VYAWGHNGYSQL---GNGTTNQGIAPVQVCTNLLIKQVVEVACGSHHSMALAADGEVFAW 152
Query: 393 GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQ 572
G N+ GQ+G + ++ + + IACG S+A+ + G+ + WG + GQ
Sbjct: 153 GYNNCGQVGSGSTANQPTPRKVTNCLHIKRVVGIACGQTSSMAVLDNGEVYGWGYNGNGQ 212
Query: 573 LGNNLGAHA-QDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
LG LG + Q P V L + V Q+ CG H++ALT+ G LY+W
Sbjct: 213 LG--LGNNGNQLTPVRVAALHSVCVNQIVCGYAHTLALTDEGLLYAW 257
Score = 73.7 bits (173), Expect = 6e-13
Identities = 40/121 (33%), Positives = 65/121 (53%), Gaps = 1/121 (0%)
Frame = +3
Query: 351 HSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVET-FKDCTISTIACGLQHSLAID 527
H L + G +Y+ G+N QLG T ++ G P V T + +ACG HS+A+
Sbjct: 86 HVLLSTEDGVVYAWGHNGYSQLGNGT-TNQGIAPVQVCTNLLIKQVVEVACGSHHSMALA 144
Query: 528 EWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYS 707
G+ F+WG ++ GQ+G+ A+ K L K V+ +ACG S+A+ ++G++Y
Sbjct: 145 ADGEVFAWGYNNCGQVGSGSTANQPTPRKVTNCLHIKRVVGIACGQTSSMAVLDNGEVYG 204
Query: 708 W 710
W
Sbjct: 205 W 205
Score = 65.3 bits (152), Expect = 2e-10
Identities = 44/146 (30%), Positives = 71/146 (48%), Gaps = 5/146 (3%)
Frame = +3
Query: 288 KPTLSKWKESDHIQAV---AAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPAL 458
+PT K HI+ V A G+ S+ + ++G +Y G N GQLG N P
Sbjct: 168 QPTPRKVTNCLHIKRVVGIACGQTSSMAVLDNGEVYGWGYNGNGQLGLGNNG-NQLTPVR 226
Query: 459 VETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATK 638
V ++ I CG H+LA+ + G ++WG+++ GQLG + P + + +
Sbjct: 227 VAALHSVCVNQIVCGYAHTLALTDEGLLYAWGANTYGQLGTG-NKNNLLSPAHIM-VEKE 284
Query: 639 NVIQV-ACGAYH-SVALTNSGDLYSW 710
V+++ AC + H S A T G +Y W
Sbjct: 285 RVVEIAACHSAHTSAAKTQGGHVYMW 310
>AK096654-1|BAC04833.1| 531|Homo sapiens protein ( Homo sapiens
cDNA FLJ39335 fis, clone OCBBF2017398, moderately
similar to Homo sapiens RCC1-like G exchanging factor
RLG mRNA. ).
Length = 531
Score = 74.5 bits (175), Expect = 3e-13
Identities = 50/167 (29%), Positives = 84/167 (50%), Gaps = 2/167 (1%)
Frame = +3
Query: 216 MFCWGNATHHELCIDGSQITDLVIKPT-LSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 392
++ WG+ + +L G+ T+ I P + + VA G HS+ L+ G +++
Sbjct: 96 VYAWGHNGYSQL---GNGTTNQGIAPVQVCTNLLIKQVVEVACGSHHSMALAADGEVFAW 152
Query: 393 GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQ 572
G N+ GQ+G + ++ + + IACG S+A+ + G+ + WG + GQ
Sbjct: 153 GYNNCGQVGSGSTANQPTPRKVTNCLHIKRVVGIACGQTSSMAVLDNGEVYGWGYNGNGQ 212
Query: 573 LGNNLGAHA-QDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
LG LG + Q P V L + V Q+ CG H++ALT+ G LY+W
Sbjct: 213 LG--LGNNGNQLTPVRVAALHSVCVNQIVCGYAHTLALTDEGLLYAW 257
Score = 73.7 bits (173), Expect = 6e-13
Identities = 40/121 (33%), Positives = 65/121 (53%), Gaps = 1/121 (0%)
Frame = +3
Query: 351 HSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVET-FKDCTISTIACGLQHSLAID 527
H L + G +Y+ G+N QLG T ++ G P V T + +ACG HS+A+
Sbjct: 86 HVLLSTEDGVVYAWGHNGYSQLGNGT-TNQGIAPVQVCTNLLIKQVVEVACGSHHSMALA 144
Query: 528 EWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYS 707
G+ F+WG ++ GQ+G+ A+ K L K V+ +ACG S+A+ ++G++Y
Sbjct: 145 ADGEVFAWGYNNCGQVGSGSTANQPTPRKVTNCLHIKRVVGIACGQTSSMAVLDNGEVYG 204
Query: 708 W 710
W
Sbjct: 205 W 205
Score = 65.3 bits (152), Expect = 2e-10
Identities = 44/146 (30%), Positives = 71/146 (48%), Gaps = 5/146 (3%)
Frame = +3
Query: 288 KPTLSKWKESDHIQAV---AAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPAL 458
+PT K HI+ V A G+ S+ + ++G +Y G N GQLG N P
Sbjct: 168 QPTPRKVTNCLHIKRVVGIACGQTSSMAVLDNGEVYGWGYNGNGQLGLGNNG-NQLTPVR 226
Query: 459 VETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATK 638
V ++ I CG H+LA+ + G ++WG+++ GQLG + P + + +
Sbjct: 227 VAALHSVCVNQIVCGYAHTLALTDEGLLYAWGANTYGQLGTG-NKNNLLSPAHIM-VEKE 284
Query: 639 NVIQV-ACGAYH-SVALTNSGDLYSW 710
V+++ AC + H S A T G +Y W
Sbjct: 285 RVVEIAACHSAHTSAAKTQGGHVYMW 310
>AJ319660-1|CAC40027.1| 531|Homo sapiens guanine nucleotide
exchange factor protein.
Length = 531
Score = 74.5 bits (175), Expect = 3e-13
Identities = 50/167 (29%), Positives = 84/167 (50%), Gaps = 2/167 (1%)
Frame = +3
Query: 216 MFCWGNATHHELCIDGSQITDLVIKPT-LSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 392
++ WG+ + +L G+ T+ I P + + VA G HS+ L+ G +++
Sbjct: 96 VYAWGHNGYSQL---GNGTTNQGIAPVQVCTNLLIKQVVEVACGSHHSMALAADGEVFAW 152
Query: 393 GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQ 572
G N+ GQ+G + ++ + + IACG S+A+ + G+ + WG + GQ
Sbjct: 153 GYNNCGQVGSGSTANQPTPRKVTNCLHIKRVVGIACGQTSSMAVLDNGEVYGWGYNGNGQ 212
Query: 573 LGNNLGAHA-QDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
LG LG + Q P V L + V Q+ CG H++ALT+ G LY+W
Sbjct: 213 LG--LGNNGNQLTPVRVAALHSVCVNQIVCGYAHTLALTDEGLLYAW 257
Score = 73.7 bits (173), Expect = 6e-13
Identities = 40/121 (33%), Positives = 65/121 (53%), Gaps = 1/121 (0%)
Frame = +3
Query: 351 HSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVET-FKDCTISTIACGLQHSLAID 527
H L + G +Y+ G+N QLG T ++ G P V T + +ACG HS+A+
Sbjct: 86 HVLLSTEDGVVYAWGHNGYSQLGNGT-TNQGIAPVQVCTNLLIKQVVEVACGSHHSMALA 144
Query: 528 EWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYS 707
G+ F+WG ++ GQ+G+ A+ K L K V+ +ACG S+A+ ++G++Y
Sbjct: 145 ADGEVFAWGYNNCGQVGSGSTANQPTPRKVTNCLHIKRVVGIACGQTSSMAVLDNGEVYG 204
Query: 708 W 710
W
Sbjct: 205 W 205
Score = 65.3 bits (152), Expect = 2e-10
Identities = 44/146 (30%), Positives = 71/146 (48%), Gaps = 5/146 (3%)
Frame = +3
Query: 288 KPTLSKWKESDHIQAV---AAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPAL 458
+PT K HI+ V A G+ S+ + ++G +Y G N GQLG N P
Sbjct: 168 QPTPRKVTNCLHIKRVVGIACGQTSSMAVLDNGEVYGWGYNGNGQLGLGNNG-NQLTPVR 226
Query: 459 VETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATK 638
V ++ I CG H+LA+ + G ++WG+++ GQLG + P + + +
Sbjct: 227 VAALHSVCVNQIVCGYAHTLALTDEGLLYAWGANTYGQLGTG-NKNNLLSPAHIM-VEKE 284
Query: 639 NVIQV-ACGAYH-SVALTNSGDLYSW 710
V+++ AC + H S A T G +Y W
Sbjct: 285 RVVEIAACHSAHTSAAKTQGGHVYMW 310
>AF334406-1|AAK38372.1| 531|Homo sapiens CLLL7 protein protein.
Length = 531
Score = 74.5 bits (175), Expect = 3e-13
Identities = 50/167 (29%), Positives = 84/167 (50%), Gaps = 2/167 (1%)
Frame = +3
Query: 216 MFCWGNATHHELCIDGSQITDLVIKPT-LSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 392
++ WG+ + +L G+ T+ I P + + VA G HS+ L+ G +++
Sbjct: 96 VYAWGHNGYSQL---GNGTTNQGIAPVQVCTNLLIKQVVEVACGSHHSMALAADGEVFAW 152
Query: 393 GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQ 572
G N+ GQ+G + ++ + + IACG S+A+ + G+ + WG + GQ
Sbjct: 153 GYNNCGQVGSGSTANQPTPRKVTNCLHIKRVVGIACGQTSSMAVLDNGEVYGWGYNGNGQ 212
Query: 573 LGNNLGAHA-QDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
LG LG + Q P V L + V Q+ CG H++ALT+ G LY+W
Sbjct: 213 LG--LGNNGNQLTPVRVAALHSVCVNQIVCGYAHTLALTDEGLLYAW 257
Score = 73.7 bits (173), Expect = 6e-13
Identities = 40/121 (33%), Positives = 65/121 (53%), Gaps = 1/121 (0%)
Frame = +3
Query: 351 HSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVET-FKDCTISTIACGLQHSLAID 527
H L + G +Y+ G+N QLG T ++ G P V T + +ACG HS+A+
Sbjct: 86 HVLLSTEDGVVYAWGHNGYSQLGNGT-TNQGIAPVQVCTNLLIKQVVEVACGSHHSMALA 144
Query: 528 EWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYS 707
G+ F+WG ++ GQ+G+ A+ K L K V+ +ACG S+A+ ++G++Y
Sbjct: 145 ADGEVFAWGYNNCGQVGSGSTANQPTPRKVTNCLHIKRVVGIACGQTSSMAVLDNGEVYG 204
Query: 708 W 710
W
Sbjct: 205 W 205
Score = 65.3 bits (152), Expect = 2e-10
Identities = 44/146 (30%), Positives = 71/146 (48%), Gaps = 5/146 (3%)
Frame = +3
Query: 288 KPTLSKWKESDHIQAV---AAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPAL 458
+PT K HI+ V A G+ S+ + ++G +Y G N GQLG N P
Sbjct: 168 QPTPRKVTNCLHIKRVVGIACGQTSSMAVLDNGEVYGWGYNGNGQLGLGNNG-NQLTPVR 226
Query: 459 VETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATK 638
V ++ I CG H+LA+ + G ++WG+++ GQLG + P + + +
Sbjct: 227 VAALHSVCVNQIVCGYAHTLALTDEGLLYAWGANTYGQLGTG-NKNNLLSPAHIM-VEKE 284
Query: 639 NVIQV-ACGAYH-SVALTNSGDLYSW 710
V+++ AC + H S A T G +Y W
Sbjct: 285 RVVEIAACHSAHTSAAKTQGGHVYMW 310
>BC142946-1|AAI42947.1| 457|Homo sapiens RCC2 protein protein.
Length = 457
Score = 74.1 bits (174), Expect = 4e-13
Identities = 42/120 (35%), Positives = 65/120 (54%)
Frame = +3
Query: 351 HSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDE 530
HSL ++ G L+S G N+ GQLG ++ + P L+E I + ACG H+LA+ E
Sbjct: 96 HSLLITTEGKLWSWGRNEKGQLGHG-DTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTE 154
Query: 531 WGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
G F++G + MGQLG A P + + + ++ACGA S+ + G+LYS+
Sbjct: 155 TGSVFAFGENKMGQLGLGNQTDAVPSPAQIM-YNGQPITKMACGAEFSMIMDCKGNLYSF 213
Score = 68.1 bits (159), Expect = 3e-11
Identities = 56/189 (29%), Positives = 90/189 (47%), Gaps = 23/189 (12%)
Frame = +3
Query: 213 KMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 392
K++ WG +L G T V P L + + I + A G H+L L+ +G +++
Sbjct: 105 KLWSWGRNEKGQL---GHGDTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTETGSVFAF 161
Query: 393 GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQ 572
G N +GQLG ++D +PA + + I+ +ACG + S+ +D G +S+G GQ
Sbjct: 162 GENKMGQLGLGNQTDAVPSPAQI-MYNGQPITKMACGAEFSMIMDCKGNLYSFGCPEYGQ 220
Query: 573 LGNNLG----AHAQ-----------------DKPKFVKGLATKNVI--QVACGAYHSVAL 683
LG+N A AQ +K K + L NV+ VACGA H++ L
Sbjct: 221 LGHNSDGKFIARAQRIEYDCELVPRRVAIFIEKTKDGQILPVPNVVVRDVACGANHTLVL 280
Query: 684 TNSGDLYSW 710
+ ++SW
Sbjct: 281 DSQKRVFSW 289
Score = 44.4 bits (100), Expect = 4e-04
Identities = 52/192 (27%), Positives = 81/192 (42%), Gaps = 27/192 (14%)
Frame = +3
Query: 216 MFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCG 395
+F +G +L + G+Q TD V P + I +A G S+ + G+LYS G
Sbjct: 158 VFAFGENKMGQLGL-GNQ-TDAVPSPAQIMYN-GQPITKMACGAEFSMIMDCKGNLYSFG 214
Query: 396 NNDVGQLGRQT-----------ESDNGKNPALVETFKDCT------------ISTIACGL 506
+ GQLG + E D P V F + T + +ACG
Sbjct: 215 CPEYGQLGHNSDGKFIARAQRIEYDCELVPRRVAIFIEKTKDGQILPVPNVVVRDVACGA 274
Query: 507 QHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDK--PKFVK--GLATKNVIQVACGAYHS 674
H+L +D + FSWG G+LG+ A +D+ P+ VK + ++ G S
Sbjct: 275 NHTLVLDSQKRVFSWGFGGYGRLGH---AEQKDEMVPRLVKLFDFPGRGASRIYAGYTCS 331
Query: 675 VALTNSGDLYSW 710
A++ G L+ W
Sbjct: 332 FAVSEVGGLFFW 343
>BC053908-1|AAH53908.1| 522|Homo sapiens RCC2 protein protein.
Length = 522
Score = 74.1 bits (174), Expect = 4e-13
Identities = 42/120 (35%), Positives = 65/120 (54%)
Frame = +3
Query: 351 HSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDE 530
HSL ++ G L+S G N+ GQLG ++ + P L+E I + ACG H+LA+ E
Sbjct: 161 HSLLITTEGKLWSWGRNEKGQLGHG-DTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTE 219
Query: 531 WGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
G F++G + MGQLG A P + + + ++ACGA S+ + G+LYS+
Sbjct: 220 TGSVFAFGENKMGQLGLGNQTDAVPSPAQIM-YNGQPITKMACGAEFSMIMDCKGNLYSF 278
Score = 68.1 bits (159), Expect = 3e-11
Identities = 56/189 (29%), Positives = 90/189 (47%), Gaps = 23/189 (12%)
Frame = +3
Query: 213 KMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 392
K++ WG +L G T V P L + + I + A G H+L L+ +G +++
Sbjct: 170 KLWSWGRNEKGQL---GHGDTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTETGSVFAF 226
Query: 393 GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQ 572
G N +GQLG ++D +PA + + I+ +ACG + S+ +D G +S+G GQ
Sbjct: 227 GENKMGQLGLGNQTDAVPSPAQI-MYNGQPITKMACGAEFSMIMDCKGNLYSFGCPEYGQ 285
Query: 573 LGNNLG----AHAQ-----------------DKPKFVKGLATKNVI--QVACGAYHSVAL 683
LG+N A AQ +K K + L NV+ VACGA H++ L
Sbjct: 286 LGHNSDGKFIARAQRIEYDCELVPRRVAIFIEKTKDGQILPVPNVVVRDVACGANHTLVL 345
Query: 684 TNSGDLYSW 710
+ ++SW
Sbjct: 346 DSQKRVFSW 354
Score = 46.0 bits (104), Expect = 1e-04
Identities = 53/192 (27%), Positives = 81/192 (42%), Gaps = 27/192 (14%)
Frame = +3
Query: 216 MFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCG 395
+F +G +L + G+Q TD V P + I +A G S+ + G+LYS G
Sbjct: 223 VFAFGENKMGQLGL-GNQ-TDAVPSPAQIMYN-GQPITKMACGAEFSMIMDCKGNLYSFG 279
Query: 396 NNDVGQLGRQT-----------ESDNGKNPALVETFKDCT------------ISTIACGL 506
+ GQLG + E D P V F + T + +ACG
Sbjct: 280 CPEYGQLGHNSDGKFIARAQRIEYDCELVPRRVAIFIEKTKDGQILPVPNVVVRDVACGA 339
Query: 507 QHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDK--PKFVK--GLATKNVIQVACGAYHS 674
H+L +D + FSWG G+LG+ A +D+ P+ VK + Q+ G S
Sbjct: 340 NHTLVLDSQKRVFSWGFGGYGRLGH---AEQKDEMVPRLVKLFDFPGRGASQIYAGYTCS 396
Query: 675 VALTNSGDLYSW 710
A++ G L+ W
Sbjct: 397 FAVSEVGGLFFW 408
>BC042141-1|AAH42141.1| 522|Homo sapiens regulator of chromosome
condensation 2 protein.
Length = 522
Score = 74.1 bits (174), Expect = 4e-13
Identities = 42/120 (35%), Positives = 65/120 (54%)
Frame = +3
Query: 351 HSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDE 530
HSL ++ G L+S G N+ GQLG ++ + P L+E I + ACG H+LA+ E
Sbjct: 161 HSLLITTEGKLWSWGRNEKGQLGHG-DTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTE 219
Query: 531 WGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
G F++G + MGQLG A P + + + ++ACGA S+ + G+LYS+
Sbjct: 220 TGSVFAFGENKMGQLGLGNQTDAVPSPAQIM-YNGQPITKMACGAEFSMIMDCKGNLYSF 278
Score = 68.1 bits (159), Expect = 3e-11
Identities = 56/189 (29%), Positives = 90/189 (47%), Gaps = 23/189 (12%)
Frame = +3
Query: 213 KMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 392
K++ WG +L G T V P L + + I + A G H+L L+ +G +++
Sbjct: 170 KLWSWGRNEKGQL---GHGDTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTETGSVFAF 226
Query: 393 GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQ 572
G N +GQLG ++D +PA + + I+ +ACG + S+ +D G +S+G GQ
Sbjct: 227 GENKMGQLGLGNQTDAVPSPAQI-MYNGQPITKMACGAEFSMIMDCKGNLYSFGCPEYGQ 285
Query: 573 LGNNLG----AHAQ-----------------DKPKFVKGLATKNVI--QVACGAYHSVAL 683
LG+N A AQ +K K + L NV+ VACGA H++ L
Sbjct: 286 LGHNSDGKFIARAQRIEYDCELVPRRVAIFIEKTKDGQILPVPNVVVRDVACGANHTLVL 345
Query: 684 TNSGDLYSW 710
+ ++SW
Sbjct: 346 DSQKRVFSW 354
Score = 46.0 bits (104), Expect = 1e-04
Identities = 53/192 (27%), Positives = 81/192 (42%), Gaps = 27/192 (14%)
Frame = +3
Query: 216 MFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCG 395
+F +G +L + G+Q TD V P + I +A G S+ + G+LYS G
Sbjct: 223 VFAFGENKMGQLGL-GNQ-TDAVPSPAQIMYN-GQPITKMACGAEFSMIMDCKGNLYSFG 279
Query: 396 NNDVGQLGRQT-----------ESDNGKNPALVETFKDCT------------ISTIACGL 506
+ GQLG + E D P V F + T + +ACG
Sbjct: 280 CPEYGQLGHNSDGKFIARAQRIEYDCELVPRRVAIFIEKTKDGQILPVPNVVVRDVACGA 339
Query: 507 QHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDK--PKFVK--GLATKNVIQVACGAYHS 674
H+L +D + FSWG G+LG+ A +D+ P+ VK + Q+ G S
Sbjct: 340 NHTLVLDSQKRVFSWGFGGYGRLGH---AEQKDEMVPRLVKLFDFPGRGASQIYAGYTCS 396
Query: 675 VALTNSGDLYSW 710
A++ G L+ W
Sbjct: 397 FAVSEVGGLFFW 408
>BC038104-1|AAH38104.1| 355|Homo sapiens RCBTB1 protein protein.
Length = 355
Score = 74.1 bits (174), Expect = 4e-13
Identities = 43/127 (33%), Positives = 68/127 (53%), Gaps = 1/127 (0%)
Frame = +3
Query: 333 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQH 512
VA G HS+ L+ G +++ G N+ GQ+G + ++ + + IACG
Sbjct: 133 VACGSHHSMALAADGEVFAWGYNNCGQVGSGSTANQPTPRKVTNCLHIKRVVGIACGQTS 192
Query: 513 SLAIDEWGQPFSWGSDSMGQLGNNLGAHA-QDKPKFVKGLATKNVIQVACGAYHSVALTN 689
S+A+ + G+ + WG + GQLG LG + Q P V L + V Q+ CG H++ALT+
Sbjct: 193 SMAVLDNGEVYGWGYNGNGQLG--LGNNGNQLTPVRVAALHSVCVNQIVCGYAHTLALTD 250
Query: 690 SGDLYSW 710
G LY+W
Sbjct: 251 EGLLYAW 257
Score = 73.7 bits (173), Expect = 6e-13
Identities = 36/120 (30%), Positives = 61/120 (50%)
Frame = +3
Query: 351 HSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDE 530
H L + G +Y+ G+N QLG T + + + +ACG HS+A+
Sbjct: 86 HVLLSTEDGVVYAWGHNGYSQLGNGTTNQGIATVQVCTNLLIKQVVEVACGSHHSMALAA 145
Query: 531 WGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
G+ F+WG ++ GQ+G+ A+ K L K V+ +ACG S+A+ ++G++Y W
Sbjct: 146 DGEVFAWGYNNCGQVGSGSTANQPTPRKVTNCLHIKRVVGIACGQTSSMAVLDNGEVYGW 205
Score = 65.3 bits (152), Expect = 2e-10
Identities = 44/146 (30%), Positives = 71/146 (48%), Gaps = 5/146 (3%)
Frame = +3
Query: 288 KPTLSKWKESDHIQAV---AAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPAL 458
+PT K HI+ V A G+ S+ + ++G +Y G N GQLG N P
Sbjct: 168 QPTPRKVTNCLHIKRVVGIACGQTSSMAVLDNGEVYGWGYNGNGQLGLGNNG-NQLTPVR 226
Query: 459 VETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATK 638
V ++ I CG H+LA+ + G ++WG+++ GQLG + P + + +
Sbjct: 227 VAALHSVCVNQIVCGYAHTLALTDEGLLYAWGANTYGQLGTG-NKNNLLSPAHIM-VEKE 284
Query: 639 NVIQV-ACGAYH-SVALTNSGDLYSW 710
V+++ AC + H S A T G +Y W
Sbjct: 285 RVVEIAACHSAHTSAAKTQGGHVYMW 310
>AL359612-1|CAB94882.1| 333|Homo sapiens hypothetical protein
protein.
Length = 333
Score = 74.1 bits (174), Expect = 4e-13
Identities = 42/120 (35%), Positives = 65/120 (54%)
Frame = +3
Query: 351 HSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDE 530
HSL ++ G L+S G N+ GQLG ++ + P L+E I + ACG H+LA+ E
Sbjct: 17 HSLLITTEGKLWSWGRNEKGQLGHG-DTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTE 75
Query: 531 WGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
G F++G + MGQLG A P + + + ++ACGA S+ + G+LYS+
Sbjct: 76 TGSVFAFGENKMGQLGLGNQTDAVPSPAQIM-YNGQPITKMACGAEFSMIMDCKGNLYSF 134
Score = 68.1 bits (159), Expect = 3e-11
Identities = 56/189 (29%), Positives = 90/189 (47%), Gaps = 23/189 (12%)
Frame = +3
Query: 213 KMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 392
K++ WG +L G T V P L + + I + A G H+L L+ +G +++
Sbjct: 26 KLWSWGRNEKGQL---GHGDTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTETGSVFAF 82
Query: 393 GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQ 572
G N +GQLG ++D +PA + + I+ +ACG + S+ +D G +S+G GQ
Sbjct: 83 GENKMGQLGLGNQTDAVPSPAQI-MYNGQPITKMACGAEFSMIMDCKGNLYSFGCPEYGQ 141
Query: 573 LGNNLG----AHAQ-----------------DKPKFVKGLATKNVI--QVACGAYHSVAL 683
LG+N A AQ +K K + L NV+ VACGA H++ L
Sbjct: 142 LGHNSDGKFIARAQRIEYDCELVPRRVAIFIEKTKDGQILPVPNVVVRDVACGANHTLVL 201
Query: 684 TNSGDLYSW 710
+ ++SW
Sbjct: 202 DSQKRVFSW 210
Score = 46.0 bits (104), Expect = 1e-04
Identities = 53/192 (27%), Positives = 81/192 (42%), Gaps = 27/192 (14%)
Frame = +3
Query: 216 MFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCG 395
+F +G +L + G+Q TD V P + I +A G S+ + G+LYS G
Sbjct: 79 VFAFGENKMGQLGL-GNQ-TDAVPSPAQIMYN-GQPITKMACGAEFSMIMDCKGNLYSFG 135
Query: 396 NNDVGQLGRQT-----------ESDNGKNPALVETFKDCT------------ISTIACGL 506
+ GQLG + E D P V F + T + +ACG
Sbjct: 136 CPEYGQLGHNSDGKFIARAQRIEYDCELVPRRVAIFIEKTKDGQILPVPNVVVRDVACGA 195
Query: 507 QHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDK--PKFVK--GLATKNVIQVACGAYHS 674
H+L +D + FSWG G+LG+ A +D+ P+ VK + Q+ G S
Sbjct: 196 NHTLVLDSQKRVFSWGFGGYGRLGH---AEQKDEMVPRLVKLFDFPGRGASQIYAGYTCS 252
Query: 675 VALTNSGDLYSW 710
A++ G L+ W
Sbjct: 253 FAVSEVGGLFFW 264
>AJ421269-1|CAD13148.1| 522|Homo sapiens RCC1-like protein protein.
Length = 522
Score = 74.1 bits (174), Expect = 4e-13
Identities = 42/120 (35%), Positives = 65/120 (54%)
Frame = +3
Query: 351 HSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDE 530
HSL ++ G L+S G N+ GQLG ++ + P L+E I + ACG H+LA+ E
Sbjct: 161 HSLLITTEGKLWSWGRNEKGQLGHG-DTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTE 219
Query: 531 WGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
G F++G + MGQLG A P + + + ++ACGA S+ + G+LYS+
Sbjct: 220 TGSVFAFGENKMGQLGLGNQTDAVPSPAQIM-YNGQPITKMACGAEFSMIMDCKGNLYSF 278
Score = 68.1 bits (159), Expect = 3e-11
Identities = 56/189 (29%), Positives = 90/189 (47%), Gaps = 23/189 (12%)
Frame = +3
Query: 213 KMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 392
K++ WG +L G T V P L + + I + A G H+L L+ +G +++
Sbjct: 170 KLWSWGRNEKGQL---GHGDTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTETGSVFAF 226
Query: 393 GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQ 572
G N +GQLG ++D +PA + + I+ +ACG + S+ +D G +S+G GQ
Sbjct: 227 GENKMGQLGLGNQTDAVPSPAQI-MYNGQPITKMACGAEFSMIMDCKGNLYSFGCPEYGQ 285
Query: 573 LGNNLG----AHAQ-----------------DKPKFVKGLATKNVI--QVACGAYHSVAL 683
LG+N A AQ +K K + L NV+ VACGA H++ L
Sbjct: 286 LGHNSDGKFIARAQRIEYDCELVPRRVAIFIEKTKDGQILPVPNVVVRDVACGANHTLVL 345
Query: 684 TNSGDLYSW 710
+ ++SW
Sbjct: 346 DSQKRVFSW 354
Score = 46.0 bits (104), Expect = 1e-04
Identities = 53/192 (27%), Positives = 81/192 (42%), Gaps = 27/192 (14%)
Frame = +3
Query: 216 MFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCG 395
+F +G +L + G+Q TD V P + I +A G S+ + G+LYS G
Sbjct: 223 VFAFGENKMGQLGL-GNQ-TDAVPSPAQIMYN-GQPITKMACGAEFSMIMDCKGNLYSFG 279
Query: 396 NNDVGQLGRQT-----------ESDNGKNPALVETFKDCT------------ISTIACGL 506
+ GQLG + E D P V F + T + +ACG
Sbjct: 280 CPEYGQLGHNSDGKFIARAQRIEYDCELVPRRVAIFIEKTKDGQILPVPNVVVRDVACGA 339
Query: 507 QHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDK--PKFVK--GLATKNVIQVACGAYHS 674
H+L +D + FSWG G+LG+ A +D+ P+ VK + Q+ G S
Sbjct: 340 NHTLVLDSQKRVFSWGFGGYGRLGH---AEQKDEMVPRLVKLFDFPGRGASQIYAGYTCS 396
Query: 675 VALTNSGDLYSW 710
A++ G L+ W
Sbjct: 397 FAVSEVGGLFFW 408
>AB040903-1|BAA95994.1| 564|Homo sapiens KIAA1470 protein protein.
Length = 564
Score = 74.1 bits (174), Expect = 4e-13
Identities = 42/120 (35%), Positives = 65/120 (54%)
Frame = +3
Query: 351 HSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDE 530
HSL ++ G L+S G N+ GQLG ++ + P L+E I + ACG H+LA+ E
Sbjct: 203 HSLLITTEGKLWSWGRNEKGQLGHG-DTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTE 261
Query: 531 WGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
G F++G + MGQLG A P + + + ++ACGA S+ + G+LYS+
Sbjct: 262 TGSVFAFGENKMGQLGLGNQTDAVPSPAQIM-YNGQPITKMACGAEFSMIMDCKGNLYSF 320
Score = 68.1 bits (159), Expect = 3e-11
Identities = 56/189 (29%), Positives = 90/189 (47%), Gaps = 23/189 (12%)
Frame = +3
Query: 213 KMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 392
K++ WG +L G T V P L + + I + A G H+L L+ +G +++
Sbjct: 212 KLWSWGRNEKGQL---GHGDTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTETGSVFAF 268
Query: 393 GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQ 572
G N +GQLG ++D +PA + + I+ +ACG + S+ +D G +S+G GQ
Sbjct: 269 GENKMGQLGLGNQTDAVPSPAQI-MYNGQPITKMACGAEFSMIMDCKGNLYSFGCPEYGQ 327
Query: 573 LGNNLG----AHAQ-----------------DKPKFVKGLATKNVI--QVACGAYHSVAL 683
LG+N A AQ +K K + L NV+ VACGA H++ L
Sbjct: 328 LGHNSDGKFIARAQRIEYDCELVPRRVAIFIEKTKDGQILPVPNVVVRDVACGANHTLVL 387
Query: 684 TNSGDLYSW 710
+ ++SW
Sbjct: 388 DSQKRVFSW 396
Score = 46.0 bits (104), Expect = 1e-04
Identities = 53/192 (27%), Positives = 81/192 (42%), Gaps = 27/192 (14%)
Frame = +3
Query: 216 MFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCG 395
+F +G +L + G+Q TD V P + I +A G S+ + G+LYS G
Sbjct: 265 VFAFGENKMGQLGL-GNQ-TDAVPSPAQIMYN-GQPITKMACGAEFSMIMDCKGNLYSFG 321
Query: 396 NNDVGQLGRQT-----------ESDNGKNPALVETFKDCT------------ISTIACGL 506
+ GQLG + E D P V F + T + +ACG
Sbjct: 322 CPEYGQLGHNSDGKFIARAQRIEYDCELVPRRVAIFIEKTKDGQILPVPNVVVRDVACGA 381
Query: 507 QHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDK--PKFVK--GLATKNVIQVACGAYHS 674
H+L +D + FSWG G+LG+ A +D+ P+ VK + Q+ G S
Sbjct: 382 NHTLVLDSQKRVFSWGFGGYGRLGH---AEQKDEMVPRLVKLFDFPGRGASQIYAGYTCS 438
Query: 675 VALTNSGDLYSW 710
A++ G L+ W
Sbjct: 439 FAVSEVGGLFFW 450
>BC040929-1|AAH40929.1| 651|Homo sapiens HERC1 protein protein.
Length = 651
Score = 72.1 bits (169), Expect = 2e-12
Identities = 42/121 (34%), Positives = 63/121 (52%)
Frame = +3
Query: 324 IQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACG 503
I+ VA G S+ L+ GH+Y+ G + + L + + N P + I +A G
Sbjct: 31 IKKVACGTQFSVALTKDGHVYTFGQDRLIGLP-EGRARNHNRPQQIPVLAGVIIEDVAVG 89
Query: 504 LQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVAL 683
+H+LA+ G ++WGS+S GQLG H ++ P V GL KNV Q++ G HS A
Sbjct: 90 AEHTLALASNGDVYAWGSNSEGQLGLGHTNHVRE-PTLVTGLQGKNVRQISAGRCHSAAW 148
Query: 684 T 686
T
Sbjct: 149 T 149
Score = 57.6 bits (133), Expect = 4e-08
Identities = 32/106 (30%), Positives = 57/106 (53%)
Frame = +3
Query: 393 GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQ 572
G+ D G+LG + +P ++ I +ACG Q S+A+ + G +++G D +
Sbjct: 2 GDGDYGKLGLGNSTAKS-SPQKIDVLCGIGIKKVACGTQFSVALTKDGHVYTFGQDRLIG 60
Query: 573 LGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
L A ++P+ + LA + VA GA H++AL ++GD+Y+W
Sbjct: 61 LPEGR-ARNHNRPQQIPVLAGVIIEDVAVGAEHTLALASNGDVYAW 105
>X97668-1|CAA66258.1| 815|Homo sapiens XLRP3 protein.
Length = 815
Score = 71.3 bits (167), Expect = 3e-12
Identities = 46/164 (28%), Positives = 80/164 (48%)
Frame = +3
Query: 213 KMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 392
K++ +G+ +L + GS+ + KPT K + + ++ A G H+L + G++Y+
Sbjct: 55 KLYMFGSNNWGQLGL-GSK--SAISKPTCVKALKPEKVKLAACGRNHTLVSTEGGNVYAT 111
Query: 393 GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQ 572
G N+ GQLG + + + I ++ G S A+ E G+ F WG +S GQ
Sbjct: 112 GGNNEGQLGLGDTEERNTFHVISFFTSEHKIKQLSAGSNTSAALTEDGRLFMWGDNSEGQ 171
Query: 573 LGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLY 704
+G ++ + G K V ++CG YHS +T G+LY
Sbjct: 172 IGLKNVSNVCVPQQVTIG---KPVSWISCGYYHSAFVTTDGELY 212
Score = 68.5 bits (160), Expect = 2e-11
Identities = 37/167 (22%), Positives = 85/167 (50%), Gaps = 1/167 (0%)
Frame = +3
Query: 213 KMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 392
++F WG+ + ++ + ++++ + ++ K + ++ G +HS +++ G LY
Sbjct: 160 RLFMWGDNSEGQIGL--KNVSNVCVPQQVTIGKP---VSWISCGYYHSAFVTTDGELYVF 214
Query: 393 GNNDVGQLGRQTES-DNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMG 569
G + G+LG + N + P LV + I +ACG +H++ + E +++G G
Sbjct: 215 GEPENGKLGLPNQLLGNHRTPQLVSEIPEKVIQ-VACGGEHTVVLTE-NAVYTFGLGQFG 272
Query: 570 QLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
QLG +PK ++ + + + ++CG H+ +T+ G +Y++
Sbjct: 273 QLGLGTFLFETSEPKVIENIRDQTISYISCGENHTALITDIGLMYTF 319
Score = 66.9 bits (156), Expect = 7e-11
Identities = 43/137 (31%), Positives = 68/137 (49%), Gaps = 2/137 (1%)
Frame = +3
Query: 306 WKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTI 485
W ++D ++ G+ HS ++ + LY G+N+ GQLG ++S K P V+ K +
Sbjct: 31 WFKNDVPVHLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISK-PTCVKALKPEKV 89
Query: 486 STIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATK--NVIQVAC 659
ACG H+L E G ++ G ++ GQLG LG + V T + Q++
Sbjct: 90 KLAACGRNHTLVSTEGGNVYATGGNNEGQLG--LGDTEERNTFHVISFFTSEHKIKQLSA 147
Query: 660 GAYHSVALTNSGDLYSW 710
G+ S ALT G L+ W
Sbjct: 148 GSNTSAALTEDGRLFMW 164
Score = 54.8 bits (126), Expect = 3e-07
Identities = 37/116 (31%), Positives = 53/116 (45%), Gaps = 1/116 (0%)
Frame = +3
Query: 333 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQH 512
VA G H++ L+ + +Y+ G GQLG T P ++E +D TIS I+CG H
Sbjct: 248 VACGGEHTVVLTENA-VYTFGLGQFGQLGLGTFLFETSEPKVIENIRDQTISYISCGENH 306
Query: 513 SLAIDEWGQPFSWGSDSMGQLGNNLGAHAQD-KPKFVKGLATKNVIQVACGAYHSV 677
+ I + G +++G G+LG L P V VACG H V
Sbjct: 307 TALITDIGLMYTFGDGRHGKLGLGLENFTNHFIPTLCSNFLRFIVKLVACGGCHMV 362
>U57629-1|AAC50481.1| 815|Homo sapiens retinitis pigmentosa GTPase
regulator protein.
Length = 815
Score = 71.3 bits (167), Expect = 3e-12
Identities = 46/164 (28%), Positives = 80/164 (48%)
Frame = +3
Query: 213 KMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 392
K++ +G+ +L + GS+ + KPT K + + ++ A G H+L + G++Y+
Sbjct: 55 KLYMFGSNNWGQLGL-GSK--SAISKPTCVKALKPEKVKLAACGRNHTLVSTEGGNVYAT 111
Query: 393 GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQ 572
G N+ GQLG + + + I ++ G S A+ E G+ F WG +S GQ
Sbjct: 112 GGNNEGQLGLGDTEERNTFHVISFFTSEHKIKQLSAGSNTSAALTEDGRLFMWGDNSEGQ 171
Query: 573 LGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLY 704
+G ++ + G K V ++CG YHS +T G+LY
Sbjct: 172 IGLKNVSNVCVPQQVTIG---KPVSWISCGYYHSAFVTTDGELY 212
Score = 68.5 bits (160), Expect = 2e-11
Identities = 37/167 (22%), Positives = 85/167 (50%), Gaps = 1/167 (0%)
Frame = +3
Query: 213 KMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 392
++F WG+ + ++ + ++++ + ++ K + ++ G +HS +++ G LY
Sbjct: 160 RLFMWGDNSEGQIGL--KNVSNVCVPQQVTIGKP---VSWISCGYYHSAFVTTDGELYVF 214
Query: 393 GNNDVGQLGRQTES-DNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMG 569
G + G+LG + N + P LV + I +ACG +H++ + E +++G G
Sbjct: 215 GEPENGKLGLPNQLLGNHRTPQLVSEIPEKVIQ-VACGGEHTVVLTE-NAVYTFGLGQFG 272
Query: 570 QLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
QLG +PK ++ + + + ++CG H+ +T+ G +Y++
Sbjct: 273 QLGLGTFLFETSEPKVIENIRDQTISYISCGENHTALITDIGLMYTF 319
Score = 66.9 bits (156), Expect = 7e-11
Identities = 43/137 (31%), Positives = 68/137 (49%), Gaps = 2/137 (1%)
Frame = +3
Query: 306 WKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTI 485
W ++D ++ G+ HS ++ + LY G+N+ GQLG ++S K P V+ K +
Sbjct: 31 WFKNDVPVHLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISK-PTCVKALKPEKV 89
Query: 486 STIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATK--NVIQVAC 659
ACG H+L E G ++ G ++ GQLG LG + V T + Q++
Sbjct: 90 KLAACGRNHTLVSTEGGNVYATGGNNEGQLG--LGDTEERNTFHVISFFTSEHKIKQLSA 147
Query: 660 GAYHSVALTNSGDLYSW 710
G+ S ALT G L+ W
Sbjct: 148 GSNTSAALTEDGRLFMW 164
Score = 54.8 bits (126), Expect = 3e-07
Identities = 37/116 (31%), Positives = 53/116 (45%), Gaps = 1/116 (0%)
Frame = +3
Query: 333 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQH 512
VA G H++ L+ + +Y+ G GQLG T P ++E +D TIS I+CG H
Sbjct: 248 VACGGEHTVVLTENA-VYTFGLGQFGQLGLGTFLFETSEPKVIENIRDQTISYISCGENH 306
Query: 513 SLAIDEWGQPFSWGSDSMGQLGNNLGAHAQD-KPKFVKGLATKNVIQVACGAYHSV 677
+ I + G +++G G+LG L P V VACG H V
Sbjct: 307 TALITDIGLMYTFGDGRHGKLGLGLENFTNHFIPTLCSNFLRFIVKLVACGGCHMV 362
>BC031624-1|AAH31624.1| 480|Homo sapiens RPGR protein protein.
Length = 480
Score = 71.3 bits (167), Expect = 3e-12
Identities = 46/164 (28%), Positives = 80/164 (48%)
Frame = +3
Query: 213 KMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 392
K++ +G+ +L + GS+ + KPT K + + ++ A G H+L + G++Y+
Sbjct: 55 KLYMFGSNNWGQLGL-GSK--SAISKPTCVKALKPEKVKLAACGRNHTLVSTEGGNVYAT 111
Query: 393 GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQ 572
G N+ GQLG + + + I ++ G S A+ E G+ F WG +S GQ
Sbjct: 112 GGNNEGQLGLGDTEERNTFHVISFFTSEHKIKQLSAGSNTSAALTEDGRLFMWGDNSEGQ 171
Query: 573 LGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLY 704
+G ++ + G K V ++CG YHS +T G+LY
Sbjct: 172 IGLKNVSNVCVPQQVTIG---KPVSWISCGYYHSAFVTTDGELY 212
Score = 68.5 bits (160), Expect = 2e-11
Identities = 37/167 (22%), Positives = 85/167 (50%), Gaps = 1/167 (0%)
Frame = +3
Query: 213 KMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 392
++F WG+ + ++ + ++++ + ++ K + ++ G +HS +++ G LY
Sbjct: 160 RLFMWGDNSEGQIGL--KNVSNVCVPQQVTIGKP---VSWISCGYYHSAFVTTDGELYVF 214
Query: 393 GNNDVGQLGRQTES-DNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMG 569
G + G+LG + N + P LV + I +ACG +H++ + E +++G G
Sbjct: 215 GEPENGKLGLPNQLLGNHRTPQLVSEIPEKVIQ-VACGGEHTVVLTE-NAVYTFGLGQFG 272
Query: 570 QLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
QLG +PK ++ + + + ++CG H+ +T+ G +Y++
Sbjct: 273 QLGLGTFLFETSEPKVIENIRDQTISYISCGENHTALITDIGLMYTF 319
Score = 66.9 bits (156), Expect = 7e-11
Identities = 43/137 (31%), Positives = 68/137 (49%), Gaps = 2/137 (1%)
Frame = +3
Query: 306 WKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTI 485
W ++D ++ G+ HS ++ + LY G+N+ GQLG ++S K P V+ K +
Sbjct: 31 WFKNDVPVHLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISK-PTCVKALKPEKV 89
Query: 486 STIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATK--NVIQVAC 659
ACG H+L E G ++ G ++ GQLG LG + V T + Q++
Sbjct: 90 KLAACGRNHTLVSTEGGNVYATGGNNEGQLG--LGDTEERNTFHVISFFTSEHKIKQLSA 147
Query: 660 GAYHSVALTNSGDLYSW 710
G+ S ALT G L+ W
Sbjct: 148 GSNTSAALTEDGRLFMW 164
Score = 54.8 bits (126), Expect = 3e-07
Identities = 37/116 (31%), Positives = 53/116 (45%), Gaps = 1/116 (0%)
Frame = +3
Query: 333 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQH 512
VA G H++ L+ + +Y+ G GQLG T P ++E +D TIS I+CG H
Sbjct: 248 VACGGEHTVVLTENA-VYTFGLGQFGQLGLGTFLFETSEPKVIENIRDQTISYISCGENH 306
Query: 513 SLAIDEWGQPFSWGSDSMGQLGNNLGAHAQD-KPKFVKGLATKNVIQVACGAYHSV 677
+ I + G +++G G+LG L P V VACG H V
Sbjct: 307 TALITDIGLMYTFGDGRHGKLGLGLENFTNHFIPTLCSNFLRFIVKLVACGGCHMV 362
>AL606748-2|CAI95407.1| 815|Homo sapiens retinitis pigmentosa
GTPase regulator protein.
Length = 815
Score = 71.3 bits (167), Expect = 3e-12
Identities = 46/164 (28%), Positives = 80/164 (48%)
Frame = +3
Query: 213 KMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 392
K++ +G+ +L + GS+ + KPT K + + ++ A G H+L + G++Y+
Sbjct: 55 KLYMFGSNNWGQLGL-GSK--SAISKPTCVKALKPEKVKLAACGRNHTLVSTEGGNVYAT 111
Query: 393 GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQ 572
G N+ GQLG + + + I ++ G S A+ E G+ F WG +S GQ
Sbjct: 112 GGNNEGQLGLGDTEERNTFHVISFFTSEHKIKQLSAGSNTSAALTEDGRLFMWGDNSEGQ 171
Query: 573 LGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLY 704
+G ++ + G K V ++CG YHS +T G+LY
Sbjct: 172 IGLKNVSNVCVPQQVTIG---KPVSWISCGYYHSAFVTTDGELY 212
Score = 68.5 bits (160), Expect = 2e-11
Identities = 37/167 (22%), Positives = 85/167 (50%), Gaps = 1/167 (0%)
Frame = +3
Query: 213 KMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 392
++F WG+ + ++ + ++++ + ++ K + ++ G +HS +++ G LY
Sbjct: 160 RLFMWGDNSEGQIGL--KNVSNVCVPQQVTIGKP---VSWISCGYYHSAFVTTDGELYVF 214
Query: 393 GNNDVGQLGRQTES-DNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMG 569
G + G+LG + N + P LV + I +ACG +H++ + E +++G G
Sbjct: 215 GEPENGKLGLPNQLLGNHRTPQLVSEIPEKVIQ-VACGGEHTVVLTE-NAVYTFGLGQFG 272
Query: 570 QLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
QLG +PK ++ + + + ++CG H+ +T+ G +Y++
Sbjct: 273 QLGLGTFLFETSEPKVIENIRDQTISYISCGENHTALITDIGLMYTF 319
Score = 66.9 bits (156), Expect = 7e-11
Identities = 43/137 (31%), Positives = 68/137 (49%), Gaps = 2/137 (1%)
Frame = +3
Query: 306 WKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTI 485
W ++D ++ G+ HS ++ + LY G+N+ GQLG ++S K P V+ K +
Sbjct: 31 WFKNDVPVHLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISK-PTCVKALKPEKV 89
Query: 486 STIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATK--NVIQVAC 659
ACG H+L E G ++ G ++ GQLG LG + V T + Q++
Sbjct: 90 KLAACGRNHTLVSTEGGNVYATGGNNEGQLG--LGDTEERNTFHVISFFTSEHKIKQLSA 147
Query: 660 GAYHSVALTNSGDLYSW 710
G+ S ALT G L+ W
Sbjct: 148 GSNTSAALTEDGRLFMW 164
Score = 54.8 bits (126), Expect = 3e-07
Identities = 37/116 (31%), Positives = 53/116 (45%), Gaps = 1/116 (0%)
Frame = +3
Query: 333 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQH 512
VA G H++ L+ + +Y+ G GQLG T P ++E +D TIS I+CG H
Sbjct: 248 VACGGEHTVVLTENA-VYTFGLGQFGQLGLGTFLFETSEPKVIENIRDQTISYISCGENH 306
Query: 513 SLAIDEWGQPFSWGSDSMGQLGNNLGAHAQD-KPKFVKGLATKNVIQVACGAYHSV 677
+ I + G +++G G+LG L P V VACG H V
Sbjct: 307 TALITDIGLMYTFGDGRHGKLGLGLENFTNHFIPTLCSNFLRFIVKLVACGGCHMV 362
>AK223491-1|BAD97211.1| 815|Homo sapiens retinitis pigmentosa
GTPase regulator variant protein.
Length = 815
Score = 71.3 bits (167), Expect = 3e-12
Identities = 46/164 (28%), Positives = 80/164 (48%)
Frame = +3
Query: 213 KMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 392
K++ +G+ +L + GS+ + KPT K + + ++ A G H+L + G++Y+
Sbjct: 55 KLYMFGSNNWGQLGL-GSK--SAISKPTCVKALKPEKVKLAACGRNHTLVSTEGGNVYAT 111
Query: 393 GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQ 572
G N+ GQLG + + + I ++ G S A+ E G+ F WG +S GQ
Sbjct: 112 GGNNEGQLGLGDTEERNTFHVISFFTSEHKIKQLSAGSNTSAALTEDGRLFMWGDNSEGQ 171
Query: 573 LGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLY 704
+G ++ + G K V ++CG YHS +T G+LY
Sbjct: 172 IGLKNVSNVCVPQQVTIG---KPVSWISCGYYHSAFVTTDGELY 212
Score = 68.5 bits (160), Expect = 2e-11
Identities = 37/167 (22%), Positives = 85/167 (50%), Gaps = 1/167 (0%)
Frame = +3
Query: 213 KMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 392
++F WG+ + ++ + ++++ + ++ K + ++ G +HS +++ G LY
Sbjct: 160 RLFMWGDNSEGQIGL--KNVSNVCVPQQVTIGKP---VSWISCGYYHSAFVTTDGELYVF 214
Query: 393 GNNDVGQLGRQTES-DNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMG 569
G + G+LG + N + P LV + I +ACG +H++ + E +++G G
Sbjct: 215 GEPENGKLGLPNQLLGNHRTPQLVSEIPEKVIQ-VACGGEHTVVLTE-NAVYTFGLGQFG 272
Query: 570 QLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
QLG +PK ++ + + + ++CG H+ +T+ G +Y++
Sbjct: 273 QLGLGTFLFETSEPKVIENIRDQTISYISCGENHTALITDIGLMYTF 319
Score = 66.9 bits (156), Expect = 7e-11
Identities = 43/137 (31%), Positives = 68/137 (49%), Gaps = 2/137 (1%)
Frame = +3
Query: 306 WKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTI 485
W ++D ++ G+ HS ++ + LY G+N+ GQLG ++S K P V+ K +
Sbjct: 31 WFKNDVPVHLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISK-PTCVKALKPEKV 89
Query: 486 STIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATK--NVIQVAC 659
ACG H+L E G ++ G ++ GQLG LG + V T + Q++
Sbjct: 90 KLAACGRNHTLVSTEGGNVYATGGNNEGQLG--LGDTEERNTFHVISFFTSEHKIKQLSA 147
Query: 660 GAYHSVALTNSGDLYSW 710
G+ S ALT G L+ W
Sbjct: 148 GSNTSAALTEDGRLFMW 164
Score = 54.8 bits (126), Expect = 3e-07
Identities = 37/116 (31%), Positives = 53/116 (45%), Gaps = 1/116 (0%)
Frame = +3
Query: 333 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQH 512
VA G H++ L+ + +Y+ G GQLG T P ++E +D TIS I+CG H
Sbjct: 248 VACGGEHTVVLTENA-VYTFGLGQFGQLGLGTFLFETSEPKVIENIRDQTISYISCGENH 306
Query: 513 SLAIDEWGQPFSWGSDSMGQLGNNLGAHAQD-KPKFVKGLATKNVIQVACGAYHSV 677
+ I + G +++G G+LG L P V VACG H V
Sbjct: 307 TALITDIGLMYTFGDGRHGKLGLGLENFTNHFIPTLCSNFLRFIVKLVACGGCHMV 362
>AJ238395-1|CAB54002.1| 646|Homo sapiens RPGR protein protein.
Length = 646
Score = 71.3 bits (167), Expect = 3e-12
Identities = 46/164 (28%), Positives = 80/164 (48%)
Frame = +3
Query: 213 KMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 392
K++ +G+ +L + GS+ + KPT K + + ++ A G H+L + G++Y+
Sbjct: 55 KLYMFGSNNWGQLGL-GSK--SAISKPTCVKALKPEKVKLAACGRNHTLVSTEGGNVYAT 111
Query: 393 GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQ 572
G N+ GQLG + + + I ++ G S A+ E G+ F WG +S GQ
Sbjct: 112 GGNNEGQLGLGDTEERNTFHVISFFTSEHKIKQLSAGSNTSAALTEDGRLFMWGDNSEGQ 171
Query: 573 LGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLY 704
+G ++ + G K V ++CG YHS +T G+LY
Sbjct: 172 IGLKNVSNVCVPQQVTIG---KPVSWISCGYYHSAFVTTDGELY 212
Score = 68.5 bits (160), Expect = 2e-11
Identities = 37/167 (22%), Positives = 85/167 (50%), Gaps = 1/167 (0%)
Frame = +3
Query: 213 KMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 392
++F WG+ + ++ + ++++ + ++ K + ++ G +HS +++ G LY
Sbjct: 160 RLFMWGDNSEGQIGL--KNVSNVCVPQQVTIGKP---VSWISCGYYHSAFVTTDGELYVF 214
Query: 393 GNNDVGQLGRQTES-DNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMG 569
G + G+LG + N + P LV + I +ACG +H++ + E +++G G
Sbjct: 215 GEPENGKLGLPNQLLGNHRTPQLVSEIPEKVIQ-VACGGEHTVVLTE-NAVYTFGLGQFG 272
Query: 570 QLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
QLG +PK ++ + + + ++CG H+ +T+ G +Y++
Sbjct: 273 QLGLGTFLFETSEPKVIENIRDQTISYISCGENHTALITDIGLMYTF 319
Score = 66.9 bits (156), Expect = 7e-11
Identities = 43/137 (31%), Positives = 68/137 (49%), Gaps = 2/137 (1%)
Frame = +3
Query: 306 WKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTI 485
W ++D ++ G+ HS ++ + LY G+N+ GQLG ++S K P V+ K +
Sbjct: 31 WFKNDVPVHLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISK-PTCVKALKPEKV 89
Query: 486 STIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATK--NVIQVAC 659
ACG H+L E G ++ G ++ GQLG LG + V T + Q++
Sbjct: 90 KLAACGRNHTLVSTEGGNVYATGGNNEGQLG--LGDTEERNTFHVISFFTSEHKIKQLSA 147
Query: 660 GAYHSVALTNSGDLYSW 710
G+ S ALT G L+ W
Sbjct: 148 GSNTSAALTEDGRLFMW 164
Score = 54.8 bits (126), Expect = 3e-07
Identities = 37/116 (31%), Positives = 53/116 (45%), Gaps = 1/116 (0%)
Frame = +3
Query: 333 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQH 512
VA G H++ L+ + +Y+ G GQLG T P ++E +D TIS I+CG H
Sbjct: 248 VACGGEHTVVLTENA-VYTFGLGQFGQLGLGTFLFETSEPKVIENIRDQTISYISCGENH 306
Query: 513 SLAIDEWGQPFSWGSDSMGQLGNNLGAHAQD-KPKFVKGLATKNVIQVACGAYHSV 677
+ I + G +++G G+LG L P V VACG H V
Sbjct: 307 TALITDIGLMYTFGDGRHGKLGLGLENFTNHFIPTLCSNFLRFIVKLVACGGCHMV 362
>BC029174-1|AAH29174.1| 812|Homo sapiens ALS2 protein protein.
Length = 812
Score = 69.7 bits (163), Expect = 9e-12
Identities = 45/137 (32%), Positives = 70/137 (51%), Gaps = 6/137 (4%)
Frame = +3
Query: 291 PTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGK-NPALVET 467
P L ++ VA G FHS ++++G Y CG N GQ + + NP +
Sbjct: 82 PILENALVGQYVITVATGSFHSGAVTDNGVAYMCGENSAGQCAVANQQYVPEPNPVSIAD 141
Query: 468 FKDCTISTI-----ACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLA 632
+ + + ACG +H+LA+ + ++WG+ QLG A KP+ V+ LA
Sbjct: 142 SEASPLLAVRILQLACGEEHTLALSISREIWAWGTGC--QLGLITTAFPVTKPQKVEHLA 199
Query: 633 TKNVIQVACGAYHSVAL 683
+ V+QVACGA+HS+AL
Sbjct: 200 GRVVLQVACGAFHSLAL 216
Score = 46.4 bits (105), Expect = 1e-04
Identities = 30/77 (38%), Positives = 38/77 (49%)
Frame = +3
Query: 480 TISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVAC 659
T S A L SL + W +WG GQLG+ + +P VK L K VI +
Sbjct: 512 TYSGEADALLPSLRTEVW----TWGKGKEGQLGHG-DVLPRLQPLCVKCLDGKEVIHLEA 566
Query: 660 GAYHSVALTNSGDLYSW 710
G YHS+ALT +YSW
Sbjct: 567 GGYHSLALTAKSQVYSW 583
Score = 45.2 bits (102), Expect = 2e-04
Identities = 33/120 (27%), Positives = 54/120 (45%)
Frame = +3
Query: 339 AGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSL 518
+GE +L S +++ G GQLG P V+ + + G HSL
Sbjct: 514 SGEADALLPSLRTEVWTWGKGKEGQLGHGDVLPR-LQPLCVKCLDGKEVIHLEAGGYHSL 572
Query: 519 AIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGD 698
A+ Q +SWGS++ GQLG++ P+ K + V +A G +S+ L ++ D
Sbjct: 573 ALTAKSQVYSWGSNTFGQLGHS--DFPTTVPRLAKISSENGVWSIAAGRDYSLFLVDTED 630
Score = 40.7 bits (91), Expect = 0.005
Identities = 38/144 (26%), Positives = 63/144 (43%), Gaps = 6/144 (4%)
Frame = +3
Query: 297 LSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKD 476
L W +QA A G H + L+ G +YS G + G + +P L
Sbjct: 35 LPGWGGKTVLQA-ALGVKHGVLLTEDGEVYSFGTLP-WRSGPVEICPS--SPILENALVG 90
Query: 477 CTISTIACGLQHSLAIDEWGQPFSWGSDSMGQLG-NNLGAHAQDKPKFVKG-----LATK 638
+ T+A G HS A+ + G + G +S GQ N + P + L
Sbjct: 91 QYVITVATGSFHSGAVTDNGVAYMCGENSAGQCAVANQQYVPEPNPVSIADSEASPLLAV 150
Query: 639 NVIQVACGAYHSVALTNSGDLYSW 710
++Q+ACG H++AL+ S ++++W
Sbjct: 151 RILQLACGEEHTLALSISREIWAW 174
Score = 37.1 bits (82), Expect = 0.062
Identities = 23/78 (29%), Positives = 37/78 (47%)
Frame = +3
Query: 285 IKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVE 464
++P K + + + AG +HSL L+ +YS G+N GQLG P L +
Sbjct: 548 LQPLCVKCLDGKEVIHLEAGGYHSLALTAKSQVYSWGSNTFGQLGHSDFPTT--VPRLAK 605
Query: 465 TFKDCTISTIACGLQHSL 518
+ + +IA G +SL
Sbjct: 606 ISSENGVWSIAAGRDYSL 623
Score = 32.7 bits (71), Expect = 1.3
Identities = 14/34 (41%), Positives = 20/34 (58%)
Frame = +3
Query: 609 PKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
P+ + G K V+Q A G H V LT G++YS+
Sbjct: 32 PERLPGWGGKTVLQAALGVKHGVLLTEDGEVYSF 65
>AJ318463-1|CAC86116.1| 815|Homo sapiens retinitis pigmentosa
GTPase regulator protein.
Length = 815
Score = 69.3 bits (162), Expect = 1e-11
Identities = 45/164 (27%), Positives = 79/164 (48%)
Frame = +3
Query: 213 KMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 392
K++ +G+ +L + GS+ + KPT K + + ++ A G H+L + G++Y+
Sbjct: 55 KLYMFGSNNWGQLGL-GSK--SAISKPTCVKALKPEKVKLAACGRNHTLVSTEGGNVYAT 111
Query: 393 GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQ 572
G N+ GQLG + + + I ++ G S A+ E G+ F WG +S GQ
Sbjct: 112 GGNNEGQLGLGDTEERNTFHVISFFTSEHKIKQLSAGSNTSAALTEDGRLFMWGDNSEGQ 171
Query: 573 LGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLY 704
+G ++ + G V ++CG YHS +T G+LY
Sbjct: 172 IGLKNVSNVCVPQQVTIG---NPVSWISCGYYHSAFVTTDGELY 212
Score = 67.3 bits (157), Expect = 5e-11
Identities = 36/167 (21%), Positives = 85/167 (50%), Gaps = 1/167 (0%)
Frame = +3
Query: 213 KMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSC 392
++F WG+ + ++ + ++++ + ++ + + ++ G +HS +++ G LY
Sbjct: 160 RLFMWGDNSEGQIGL--KNVSNVCVPQQVTI---GNPVSWISCGYYHSAFVTTDGELYVF 214
Query: 393 GNNDVGQLGRQTES-DNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMG 569
G + G+LG + N + P LV + I +ACG +H++ + E +++G G
Sbjct: 215 GEPENGKLGLPNQLLGNHRTPQLVSEIPEKVIQ-VACGGEHTVVLTE-NAVYTFGLGQFG 272
Query: 570 QLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
QLG +PK ++ + + + ++CG H+ +T+ G +Y++
Sbjct: 273 QLGLGTFLFETSEPKVIENIRDQTISYISCGENHTALITDIGLMYTF 319
Score = 66.9 bits (156), Expect = 7e-11
Identities = 43/137 (31%), Positives = 68/137 (49%), Gaps = 2/137 (1%)
Frame = +3
Query: 306 WKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTI 485
W ++D ++ G+ HS ++ + LY G+N+ GQLG ++S K P V+ K +
Sbjct: 31 WFKNDVPVHLSCGDEHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISK-PTCVKALKPEKV 89
Query: 486 STIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATK--NVIQVAC 659
ACG H+L E G ++ G ++ GQLG LG + V T + Q++
Sbjct: 90 KLAACGRNHTLVSTEGGNVYATGGNNEGQLG--LGDTEERNTFHVISFFTSEHKIKQLSA 147
Query: 660 GAYHSVALTNSGDLYSW 710
G+ S ALT G L+ W
Sbjct: 148 GSNTSAALTEDGRLFMW 164
Score = 54.8 bits (126), Expect = 3e-07
Identities = 37/116 (31%), Positives = 53/116 (45%), Gaps = 1/116 (0%)
Frame = +3
Query: 333 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQH 512
VA G H++ L+ + +Y+ G GQLG T P ++E +D TIS I+CG H
Sbjct: 248 VACGGEHTVVLTENA-VYTFGLGQFGQLGLGTFLFETSEPKVIENIRDQTISYISCGENH 306
Query: 513 SLAIDEWGQPFSWGSDSMGQLGNNLGAHAQD-KPKFVKGLATKNVIQVACGAYHSV 677
+ I + G +++G G+LG L P V VACG H V
Sbjct: 307 TALITDIGLMYTFGDGRHGKLGLGLENFTNHFIPTLCSNFLRFIVKLVACGGCHMV 362
>BC071576-1|AAH71576.1| 1237|Homo sapiens ALS2 protein protein.
Length = 1237
Score = 65.3 bits (152), Expect = 2e-10
Identities = 44/137 (32%), Positives = 69/137 (50%), Gaps = 6/137 (4%)
Frame = +3
Query: 291 PTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGK-NPALVET 467
P L ++ VA G FHS ++++G Y G N GQ + + NP +
Sbjct: 82 PILENALVGQYVITVATGSFHSGAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIAD 141
Query: 468 FKDCTISTI-----ACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLA 632
+ + + ACG +H+LA+ + ++WG+ QLG A KP+ V+ LA
Sbjct: 142 SEASPLLAVRILQLACGEEHTLALSISREIWAWGTGC--QLGLITTAFPVTKPQKVEHLA 199
Query: 633 TKNVIQVACGAYHSVAL 683
+ V+QVACGA+HS+AL
Sbjct: 200 GRVVLQVACGAFHSLAL 216
Score = 48.4 bits (110), Expect = 3e-05
Identities = 31/77 (40%), Positives = 39/77 (50%)
Frame = +3
Query: 480 TISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVAC 659
T S A L SL I+ W +WG GQLG+ + +P VK L K VI +
Sbjct: 512 TYSGEADALLPSLRIEVW----TWGKGKEGQLGHG-DVLPRLQPLCVKCLDGKEVIHLEA 566
Query: 660 GAYHSVALTNSGDLYSW 710
G YHS+ALT +YSW
Sbjct: 567 GGYHSLALTAKSQVYSW 583
Score = 46.0 bits (104), Expect = 1e-04
Identities = 39/144 (27%), Positives = 64/144 (44%), Gaps = 6/144 (4%)
Frame = +3
Query: 297 LSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKD 476
L W +QA A G H + L+ G +YS G + G + +P L
Sbjct: 35 LPGWGGKTVLQA-ALGVKHGVLLTEDGEVYSFGTLP-WRSGPVEICPS--SPILENALVG 90
Query: 477 CTISTIACGLQHSLAIDEWGQPFSWGSDSMGQLG-NNLGAHAQDKPKFVKG-----LATK 638
+ T+A G HS A+ + G + WG +S GQ N + P + L
Sbjct: 91 QYVITVATGSFHSGAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIADSEASPLLAV 150
Query: 639 NVIQVACGAYHSVALTNSGDLYSW 710
++Q+ACG H++AL+ S ++++W
Sbjct: 151 RILQLACGEEHTLALSISREIWAW 174
Score = 44.4 bits (100), Expect = 4e-04
Identities = 33/120 (27%), Positives = 54/120 (45%)
Frame = +3
Query: 339 AGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSL 518
+GE +L S +++ G GQLG P V+ + + G HSL
Sbjct: 514 SGEADALLPSLRIEVWTWGKGKEGQLGHGDVLPR-LQPLCVKCLDGKEVIHLEAGGYHSL 572
Query: 519 AIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGD 698
A+ Q +SWGS++ GQLG++ P+ K + V +A G +S+ L ++ D
Sbjct: 573 ALTAKSQVYSWGSNTFGQLGHS--DFPTTVPRLAKISSENGVWSIAAGRDYSLFLVDTED 630
Score = 37.1 bits (82), Expect = 0.062
Identities = 23/78 (29%), Positives = 37/78 (47%)
Frame = +3
Query: 285 IKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVE 464
++P K + + + AG +HSL L+ +YS G+N GQLG P L +
Sbjct: 548 LQPLCVKCLDGKEVIHLEAGGYHSLALTAKSQVYSWGSNTFGQLGHSDFPTT--VPRLAK 605
Query: 465 TFKDCTISTIACGLQHSL 518
+ + +IA G +SL
Sbjct: 606 ISSENGVWSIAAGRDYSL 623
Score = 32.7 bits (71), Expect = 1.3
Identities = 14/34 (41%), Positives = 20/34 (58%)
Frame = +3
Query: 609 PKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
P+ + G K V+Q A G H V LT G++YS+
Sbjct: 32 PERLPGWGGKTVLQAALGVKHGVLLTEDGEVYSF 65
>BC004933-1|AAH04933.1| 351|Homo sapiens RCC2 protein protein.
Length = 351
Score = 65.3 bits (152), Expect = 2e-10
Identities = 55/185 (29%), Positives = 87/185 (47%), Gaps = 23/185 (12%)
Frame = +3
Query: 225 WGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNND 404
WG +L G T V P L + + I + A G H+L L+ +G +++ G N
Sbjct: 3 WGRNEKGQL---GHGDTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTETGSVFAFGENK 59
Query: 405 VGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNN 584
+GQLG ++D +PA + + I+ +ACG + S+ +D G +S+G GQLG+N
Sbjct: 60 MGQLGLGNQTDAVPSPAQI-MYNGQPITKMACGAEFSMIMDCKGNLYSFGCPEYGQLGHN 118
Query: 585 LG----AHAQ-----------------DKPKFVKGLATKNVI--QVACGAYHSVALTNSG 695
A AQ +K K + L NV+ VACGA H++ L +
Sbjct: 119 SDGKFIARAQRIEYDCELVPRRVAIFIEKTKDGQILPVPNVVVRDVACGANHTLVLDSQK 178
Query: 696 DLYSW 710
++SW
Sbjct: 179 RVFSW 183
Score = 63.3 bits (147), Expect = 8e-10
Identities = 37/109 (33%), Positives = 58/109 (53%)
Frame = +3
Query: 384 YSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDS 563
+S G N+ GQLG ++ + P L+E I + ACG H+LA+ E G F++G +
Sbjct: 1 WSWGRNEKGQLGHG-DTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTETGSVFAFGENK 59
Query: 564 MGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
MGQLG A P + + + ++ACGA S+ + G+LYS+
Sbjct: 60 MGQLGLGNQTDAVPSPAQIM-YNGQPITKMACGAEFSMIMDCKGNLYSF 107
Score = 46.0 bits (104), Expect = 1e-04
Identities = 53/192 (27%), Positives = 81/192 (42%), Gaps = 27/192 (14%)
Frame = +3
Query: 216 MFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCG 395
+F +G +L + G+Q TD V P + I +A G S+ + G+LYS G
Sbjct: 52 VFAFGENKMGQLGL-GNQ-TDAVPSPAQIMYN-GQPITKMACGAEFSMIMDCKGNLYSFG 108
Query: 396 NNDVGQLGRQT-----------ESDNGKNPALVETFKDCT------------ISTIACGL 506
+ GQLG + E D P V F + T + +ACG
Sbjct: 109 CPEYGQLGHNSDGKFIARAQRIEYDCELVPRRVAIFIEKTKDGQILPVPNVVVRDVACGA 168
Query: 507 QHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDK--PKFVK--GLATKNVIQVACGAYHS 674
H+L +D + FSWG G+LG+ A +D+ P+ VK + Q+ G S
Sbjct: 169 NHTLVLDSQKRVFSWGFGGYGRLGH---AEQKDEMVPRLVKLFDFPGRGASQIYAGYTCS 225
Query: 675 VALTNSGDLYSW 710
A++ G L+ W
Sbjct: 226 FAVSEVGGLFFW 237
>AK023024-1|BAB14362.1| 396|Homo sapiens protein ( Homo sapiens
cDNA FLJ12962 fis, clone NT2RP2005694, weakly similar to
X-LINKED RETINITIS PIGMENTOSA GTPASE REGULATOR. ).
Length = 396
Score = 65.3 bits (152), Expect = 2e-10
Identities = 44/137 (32%), Positives = 69/137 (50%), Gaps = 6/137 (4%)
Frame = +3
Query: 291 PTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGK-NPALVET 467
P L ++ VA G FHS ++++G Y G N GQ + + NP +
Sbjct: 82 PILENALVGQYVITVATGSFHSGAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIAD 141
Query: 468 FKDCTISTI-----ACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLA 632
+ + + ACG +H+LA+ + ++WG+ QLG A KP+ V+ LA
Sbjct: 142 SEASPLLAVRILQLACGEEHTLALSISREIWAWGTGC--QLGLITTAFPVTKPQKVEHLA 199
Query: 633 TKNVIQVACGAYHSVAL 683
+ V+QVACGA+HS+AL
Sbjct: 200 GRVVLQVACGAFHSLAL 216
Score = 47.2 bits (107), Expect = 6e-05
Identities = 40/145 (27%), Positives = 64/145 (44%), Gaps = 7/145 (4%)
Frame = +3
Query: 297 LSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDN-GKNPALVETFK 473
L W +QA A G H + L+ G +YS G L R + +P L
Sbjct: 35 LPGWGGKTVLQA-ALGVKHGVLLTEDGEVYSFGT----LLWRSGPVEICPSSPILENALV 89
Query: 474 DCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQLG-NNLGAHAQDKPKFVKG-----LAT 635
+ T+A G HS A+ + G + WG +S GQ N + P + L
Sbjct: 90 GQYVITVATGSFHSGAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIADSEASPLLA 149
Query: 636 KNVIQVACGAYHSVALTNSGDLYSW 710
++Q+ACG H++AL+ S ++++W
Sbjct: 150 VRILQLACGEEHTLALSISREIWAW 174
Score = 32.7 bits (71), Expect = 1.3
Identities = 14/34 (41%), Positives = 20/34 (58%)
Frame = +3
Query: 609 PKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
P+ + G K V+Q A G H V LT G++YS+
Sbjct: 32 PERLPGWGGKTVLQAALGVKHGVLLTEDGEVYSF 65
>AF391100-1|AAL14103.1| 1657|Homo sapiens alsin protein.
Length = 1657
Score = 65.3 bits (152), Expect = 2e-10
Identities = 44/137 (32%), Positives = 69/137 (50%), Gaps = 6/137 (4%)
Frame = +3
Query: 291 PTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGK-NPALVET 467
P L ++ VA G FHS ++++G Y G N GQ + + NP +
Sbjct: 82 PILENALVGQYVITVATGSFHSGAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIAD 141
Query: 468 FKDCTISTI-----ACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLA 632
+ + + ACG +H+LA+ + ++WG+ QLG A KP+ V+ LA
Sbjct: 142 SEASPLLAVRILQLACGEEHTLALSISREIWAWGTGC--QLGLITTAFPVTKPQKVEHLA 199
Query: 633 TKNVIQVACGAYHSVAL 683
+ V+QVACGA+HS+AL
Sbjct: 200 GRVVLQVACGAFHSLAL 216
Score = 47.2 bits (107), Expect = 6e-05
Identities = 40/145 (27%), Positives = 64/145 (44%), Gaps = 7/145 (4%)
Frame = +3
Query: 297 LSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDN-GKNPALVETFK 473
L W +QA A G H + L+ G +YS G L R + +P L
Sbjct: 35 LPGWGGKTVLQA-ALGVKHGVLLTEDGEVYSFGT----LLWRSGPVEICPSSPILENALV 89
Query: 474 DCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQLG-NNLGAHAQDKPKFVKG-----LAT 635
+ T+A G HS A+ + G + WG +S GQ N + P + L
Sbjct: 90 GQYVITVATGSFHSGAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIADSEASPLLA 149
Query: 636 KNVIQVACGAYHSVALTNSGDLYSW 710
++Q+ACG H++AL+ S ++++W
Sbjct: 150 VRILQLACGEEHTLALSISREIWAW 174
Score = 46.4 bits (105), Expect = 1e-04
Identities = 30/77 (38%), Positives = 38/77 (49%)
Frame = +3
Query: 480 TISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVAC 659
T S A L SL + W +WG GQLG+ + +P VK L K VI +
Sbjct: 512 TYSGEADALLPSLRTEVW----TWGKGKEGQLGHG-DVLPRLQPLCVKCLDGKEVIHLEA 566
Query: 660 GAYHSVALTNSGDLYSW 710
G YHS+ALT +YSW
Sbjct: 567 GGYHSLALTAKSQVYSW 583
Score = 45.2 bits (102), Expect = 2e-04
Identities = 33/120 (27%), Positives = 54/120 (45%)
Frame = +3
Query: 339 AGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSL 518
+GE +L S +++ G GQLG P V+ + + G HSL
Sbjct: 514 SGEADALLPSLRTEVWTWGKGKEGQLGHGDVLPR-LQPLCVKCLDGKEVIHLEAGGYHSL 572
Query: 519 AIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGD 698
A+ Q +SWGS++ GQLG++ P+ K + V +A G +S+ L ++ D
Sbjct: 573 ALTAKSQVYSWGSNTFGQLGHS--DFPTTVPRLAKISSENGVWSIAAGRDYSLFLVDTED 630
Score = 37.1 bits (82), Expect = 0.062
Identities = 23/78 (29%), Positives = 37/78 (47%)
Frame = +3
Query: 285 IKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVE 464
++P K + + + AG +HSL L+ +YS G+N GQLG P L +
Sbjct: 548 LQPLCVKCLDGKEVIHLEAGGYHSLALTAKSQVYSWGSNTFGQLGHSDFPTT--VPRLAK 605
Query: 465 TFKDCTISTIACGLQHSL 518
+ + +IA G +SL
Sbjct: 606 ISSENGVWSIAAGRDYSL 623
Score = 32.7 bits (71), Expect = 1.3
Identities = 14/34 (41%), Positives = 20/34 (58%)
Frame = +3
Query: 609 PKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
P+ + G K V+Q A G H V LT G++YS+
Sbjct: 32 PERLPGWGGKTVLQAALGVKHGVLLTEDGEVYSF 65
>AC007279-1|AAY15058.1| 1598|Homo sapiens unknown protein.
Length = 1598
Score = 65.3 bits (152), Expect = 2e-10
Identities = 44/137 (32%), Positives = 69/137 (50%), Gaps = 6/137 (4%)
Frame = +3
Query: 291 PTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGK-NPALVET 467
P L ++ VA G FHS ++++G Y G N GQ + + NP +
Sbjct: 23 PILENALVGQYVITVATGSFHSGAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIAD 82
Query: 468 FKDCTISTI-----ACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLA 632
+ + + ACG +H+LA+ + ++WG+ QLG A KP+ V+ LA
Sbjct: 83 SEASPLLAVRILQLACGEEHTLALSISREIWAWGTGC--QLGLITTAFPVTKPQKVEHLA 140
Query: 633 TKNVIQVACGAYHSVAL 683
+ V+QVACGA+HS+AL
Sbjct: 141 GRVVLQVACGAFHSLAL 157
Score = 46.4 bits (105), Expect = 1e-04
Identities = 30/77 (38%), Positives = 38/77 (49%)
Frame = +3
Query: 480 TISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVAC 659
T S A L SL + W +WG GQLG+ + +P VK L K VI +
Sbjct: 453 TYSGEADALLPSLRTEVW----TWGKGKEGQLGHG-DVLPRLQPLCVKCLDGKEVIHLEA 507
Query: 660 GAYHSVALTNSGDLYSW 710
G YHS+ALT +YSW
Sbjct: 508 GGYHSLALTAKSQVYSW 524
Score = 45.2 bits (102), Expect = 2e-04
Identities = 33/120 (27%), Positives = 54/120 (45%)
Frame = +3
Query: 339 AGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSL 518
+GE +L S +++ G GQLG P V+ + + G HSL
Sbjct: 455 SGEADALLPSLRTEVWTWGKGKEGQLGHGDVLPR-LQPLCVKCLDGKEVIHLEAGGYHSL 513
Query: 519 AIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGD 698
A+ Q +SWGS++ GQLG++ P+ K + V +A G +S+ L ++ D
Sbjct: 514 ALTAKSQVYSWGSNTFGQLGHS--DFPTTVPRLAKISSENGVWSIAAGRDYSLFLVDTED 571
Score = 42.3 bits (95), Expect = 0.002
Identities = 26/94 (27%), Positives = 45/94 (47%), Gaps = 6/94 (6%)
Frame = +3
Query: 447 NPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQLG-NNLGAHAQDKPKFVK 623
+P L + T+A G HS A+ + G + WG +S GQ N + P +
Sbjct: 22 SPILENALVGQYVITVATGSFHSGAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIA 81
Query: 624 G-----LATKNVIQVACGAYHSVALTNSGDLYSW 710
L ++Q+ACG H++AL+ S ++++W
Sbjct: 82 DSEASPLLAVRILQLACGEEHTLALSISREIWAW 115
Score = 37.1 bits (82), Expect = 0.062
Identities = 23/78 (29%), Positives = 37/78 (47%)
Frame = +3
Query: 285 IKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVE 464
++P K + + + AG +HSL L+ +YS G+N GQLG P L +
Sbjct: 489 LQPLCVKCLDGKEVIHLEAGGYHSLALTAKSQVYSWGSNTFGQLGHSDFPTT--VPRLAK 546
Query: 465 TFKDCTISTIACGLQHSL 518
+ + +IA G +SL
Sbjct: 547 ISSENGVWSIAAGRDYSL 564
>AB053306-1|BAB69015.1| 396|Homo sapiens ALS2 protein.
Length = 396
Score = 65.3 bits (152), Expect = 2e-10
Identities = 44/137 (32%), Positives = 69/137 (50%), Gaps = 6/137 (4%)
Frame = +3
Query: 291 PTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGK-NPALVET 467
P L ++ VA G FHS ++++G Y G N GQ + + NP +
Sbjct: 82 PILENALVGQYVITVATGSFHSGAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIAD 141
Query: 468 FKDCTISTI-----ACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLA 632
+ + + ACG +H+LA+ + ++WG+ QLG A KP+ V+ LA
Sbjct: 142 SEASPLLAVRILQLACGEEHTLALSISREIWAWGTGC--QLGLITTAFPVTKPQKVEHLA 199
Query: 633 TKNVIQVACGAYHSVAL 683
+ V+QVACGA+HS+AL
Sbjct: 200 GRVVLQVACGAFHSLAL 216
Score = 46.0 bits (104), Expect = 1e-04
Identities = 39/144 (27%), Positives = 64/144 (44%), Gaps = 6/144 (4%)
Frame = +3
Query: 297 LSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKD 476
L W +QA A G H + L+ G +YS G + G + +P L
Sbjct: 35 LPGWGGKTVLQA-ALGVKHGVLLTEDGEVYSFGTLP-WRSGPVEICPS--SPILENALVG 90
Query: 477 CTISTIACGLQHSLAIDEWGQPFSWGSDSMGQLG-NNLGAHAQDKPKFVKG-----LATK 638
+ T+A G HS A+ + G + WG +S GQ N + P + L
Sbjct: 91 QYVITVATGSFHSGAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIADSEASPLLAV 150
Query: 639 NVIQVACGAYHSVALTNSGDLYSW 710
++Q+ACG H++AL+ S ++++W
Sbjct: 151 RILQLACGEEHTLALSISREIWAW 174
Score = 32.7 bits (71), Expect = 1.3
Identities = 14/34 (41%), Positives = 20/34 (58%)
Frame = +3
Query: 609 PKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
P+ + G K V+Q A G H V LT G++YS+
Sbjct: 32 PERLPGWGGKTVLQAALGVKHGVLLTEDGEVYSF 65
>AB053305-1|BAB69014.1| 1657|Homo sapiens ALS2 protein.
Length = 1657
Score = 65.3 bits (152), Expect = 2e-10
Identities = 44/137 (32%), Positives = 69/137 (50%), Gaps = 6/137 (4%)
Frame = +3
Query: 291 PTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGK-NPALVET 467
P L ++ VA G FHS ++++G Y G N GQ + + NP +
Sbjct: 82 PILENALVGQYVITVATGSFHSGAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIAD 141
Query: 468 FKDCTISTI-----ACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLA 632
+ + + ACG +H+LA+ + ++WG+ QLG A KP+ V+ LA
Sbjct: 142 SEASPLLAVRILQLACGEEHTLALSISREIWAWGTGC--QLGLITTAFPVTKPQKVEHLA 199
Query: 633 TKNVIQVACGAYHSVAL 683
+ V+QVACGA+HS+AL
Sbjct: 200 GRVVLQVACGAFHSLAL 216
Score = 46.4 bits (105), Expect = 1e-04
Identities = 30/77 (38%), Positives = 38/77 (49%)
Frame = +3
Query: 480 TISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVAC 659
T S A L SL + W +WG GQLG+ + +P VK L K VI +
Sbjct: 512 TYSGEADALLPSLRTEVW----TWGKGKEGQLGHG-DVLPRLQPLCVKCLDGKEVIHLEA 566
Query: 660 GAYHSVALTNSGDLYSW 710
G YHS+ALT +YSW
Sbjct: 567 GGYHSLALTAKSQVYSW 583
Score = 46.0 bits (104), Expect = 1e-04
Identities = 39/144 (27%), Positives = 64/144 (44%), Gaps = 6/144 (4%)
Frame = +3
Query: 297 LSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKD 476
L W +QA A G H + L+ G +YS G + G + +P L
Sbjct: 35 LPGWGGKTVLQA-ALGVKHGVLLTEDGEVYSFGTLP-WRSGPVEICPS--SPILENALVG 90
Query: 477 CTISTIACGLQHSLAIDEWGQPFSWGSDSMGQLG-NNLGAHAQDKPKFVKG-----LATK 638
+ T+A G HS A+ + G + WG +S GQ N + P + L
Sbjct: 91 QYVITVATGSFHSGAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIADSEASPLLAV 150
Query: 639 NVIQVACGAYHSVALTNSGDLYSW 710
++Q+ACG H++AL+ S ++++W
Sbjct: 151 RILQLACGEEHTLALSISREIWAW 174
Score = 45.2 bits (102), Expect = 2e-04
Identities = 33/120 (27%), Positives = 54/120 (45%)
Frame = +3
Query: 339 AGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSL 518
+GE +L S +++ G GQLG P V+ + + G HSL
Sbjct: 514 SGEADALLPSLRTEVWTWGKGKEGQLGHGDVLPR-LQPLCVKCLDGKEVIHLEAGGYHSL 572
Query: 519 AIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGD 698
A+ Q +SWGS++ GQLG++ P+ K + V +A G +S+ L ++ D
Sbjct: 573 ALTAKSQVYSWGSNTFGQLGHS--DFPTTVPRLAKISSENGVWSIAAGRDYSLFLVDTED 630
Score = 37.1 bits (82), Expect = 0.062
Identities = 23/78 (29%), Positives = 37/78 (47%)
Frame = +3
Query: 285 IKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVE 464
++P K + + + AG +HSL L+ +YS G+N GQLG P L +
Sbjct: 548 LQPLCVKCLDGKEVIHLEAGGYHSLALTAKSQVYSWGSNTFGQLGHSDFPTT--VPRLAK 605
Query: 465 TFKDCTISTIACGLQHSL 518
+ + +IA G +SL
Sbjct: 606 ISSENGVWSIAAGRDYSL 623
Score = 32.7 bits (71), Expect = 1.3
Identities = 14/34 (41%), Positives = 20/34 (58%)
Frame = +3
Query: 609 PKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
P+ + G K V+Q A G H V LT G++YS+
Sbjct: 32 PERLPGWGGKTVLQAALGVKHGVLLTEDGEVYSF 65
>AB046783-1|BAB13389.2| 1658|Homo sapiens KIAA1563 protein protein.
Length = 1658
Score = 65.3 bits (152), Expect = 2e-10
Identities = 44/137 (32%), Positives = 69/137 (50%), Gaps = 6/137 (4%)
Frame = +3
Query: 291 PTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGK-NPALVET 467
P L ++ VA G FHS ++++G Y G N GQ + + NP +
Sbjct: 83 PILENALVGQYVITVATGSFHSGAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIAD 142
Query: 468 FKDCTISTI-----ACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLA 632
+ + + ACG +H+LA+ + ++WG+ QLG A KP+ V+ LA
Sbjct: 143 SEASPLLAVRILQLACGEEHTLALSISREIWAWGTGC--QLGLITTAFPVTKPQKVEHLA 200
Query: 633 TKNVIQVACGAYHSVAL 683
+ V+QVACGA+HS+AL
Sbjct: 201 GRVVLQVACGAFHSLAL 217
Score = 46.4 bits (105), Expect = 1e-04
Identities = 30/77 (38%), Positives = 38/77 (49%)
Frame = +3
Query: 480 TISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVAC 659
T S A L SL + W +WG GQLG+ + +P VK L K VI +
Sbjct: 513 TYSGEADALLPSLRTEVW----TWGKGKEGQLGHG-DVLPRLQPLCVKCLDGKEVIHLEA 567
Query: 660 GAYHSVALTNSGDLYSW 710
G YHS+ALT +YSW
Sbjct: 568 GGYHSLALTAKSQVYSW 584
Score = 46.0 bits (104), Expect = 1e-04
Identities = 39/144 (27%), Positives = 64/144 (44%), Gaps = 6/144 (4%)
Frame = +3
Query: 297 LSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKD 476
L W +QA A G H + L+ G +YS G + G + +P L
Sbjct: 36 LPGWGGKTVLQA-ALGVKHGVLLTEDGEVYSFGTLP-WRSGPVEICPS--SPILENALVG 91
Query: 477 CTISTIACGLQHSLAIDEWGQPFSWGSDSMGQLG-NNLGAHAQDKPKFVKG-----LATK 638
+ T+A G HS A+ + G + WG +S GQ N + P + L
Sbjct: 92 QYVITVATGSFHSGAVTDNGVAYMWGENSAGQCAVANQQYVPEPNPVSIADSEASPLLAV 151
Query: 639 NVIQVACGAYHSVALTNSGDLYSW 710
++Q+ACG H++AL+ S ++++W
Sbjct: 152 RILQLACGEEHTLALSISREIWAW 175
Score = 45.2 bits (102), Expect = 2e-04
Identities = 33/120 (27%), Positives = 54/120 (45%)
Frame = +3
Query: 339 AGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSL 518
+GE +L S +++ G GQLG P V+ + + G HSL
Sbjct: 515 SGEADALLPSLRTEVWTWGKGKEGQLGHGDVLPR-LQPLCVKCLDGKEVIHLEAGGYHSL 573
Query: 519 AIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGD 698
A+ Q +SWGS++ GQLG++ P+ K + V +A G +S+ L ++ D
Sbjct: 574 ALTAKSQVYSWGSNTFGQLGHS--DFPTTVPRLAKISSENGVWSIAAGRDYSLFLVDTED 631
Score = 37.1 bits (82), Expect = 0.062
Identities = 23/78 (29%), Positives = 37/78 (47%)
Frame = +3
Query: 285 IKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVE 464
++P K + + + AG +HSL L+ +YS G+N GQLG P L +
Sbjct: 549 LQPLCVKCLDGKEVIHLEAGGYHSLALTAKSQVYSWGSNTFGQLGHSDFPTT--VPRLAK 606
Query: 465 TFKDCTISTIACGLQHSL 518
+ + +IA G +SL
Sbjct: 607 ISSENGVWSIAAGRDYSL 624
Score = 32.7 bits (71), Expect = 1.3
Identities = 14/34 (41%), Positives = 20/34 (58%)
Frame = +3
Query: 609 PKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
P+ + G K V+Q A G H V LT G++YS+
Sbjct: 33 PERLPGWGGKTVLQAALGVKHGVLLTEDGEVYSF 66
>X12654-1|CAA31182.1| 421|Homo sapiens protein ( Human mRNA for
cell cycle gene RCC1. ).
Length = 421
Score = 64.9 bits (151), Expect = 3e-10
Identities = 52/143 (36%), Positives = 73/143 (51%), Gaps = 3/143 (2%)
Frame = +3
Query: 288 KPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKN-PALVE 464
KP L E D +QA A G H++ LS SG +YS G ND G LGR T + + P VE
Sbjct: 59 KPALVSIPE-DVVQAEAGG-MHTVCLSKSGQVYSFGCNDEGALGRDTSVEGSEMVPGKVE 116
Query: 465 TFKDCTISTIACGLQHSLAIDEWGQPFSWGS--DSMGQLGNNLGAHAQDKPKFVKGLATK 638
+ + ++ G H+ A+ + G+ F WGS D+ G +G L + V+
Sbjct: 117 LQE--KVVQVSAGDSHTAALTDDGRVFLWGSFRDNNGVIG--LLEPMKKSMVPVQVQLDV 172
Query: 639 NVIQVACGAYHSVALTNSGDLYS 707
V++VA G H V LT GDLY+
Sbjct: 173 PVVKVASGNDHLVMLTADGDLYT 195
Score = 61.3 bits (142), Expect = 3e-09
Identities = 40/158 (25%), Positives = 75/158 (47%), Gaps = 2/158 (1%)
Frame = +3
Query: 216 MFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQA-VAAGEFHSLYLSNSGHLYSC 392
++ +G + +H+L G++ I L+ +K S + G+ H++ + + G YS
Sbjct: 261 VYGFGLSNYHQLGTPGTE--SCFIPQNLTSFKNSTKSWVGFSGGQHHTVCMDSEGKAYSL 318
Query: 393 GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQ 572
G + G+LG ++ P L+ +S++ACG A+ + G+ F+WG + Q
Sbjct: 319 GRAEYGRLGLGEGAEEKSIPTLISRLP--AVSSVACGASVGYAVTKDGRVFAWGMGTNYQ 376
Query: 573 LGNNLGAHAQDKPKFV-KGLATKNVIQVACGAYHSVAL 683
LG A + + K L + V+ V+ G H+V L
Sbjct: 377 LGTGQDEDAWSPVEMMGKQLENRVVLSVSSGGQHTVLL 414
Score = 59.3 bits (137), Expect = 1e-08
Identities = 38/130 (29%), Positives = 64/130 (49%), Gaps = 2/130 (1%)
Frame = +3
Query: 327 QAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIAC-- 500
Q G + + +S+ GH+Y G ++ QLG +++ P + +FK+ T S +
Sbjct: 243 QDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTPG-TESCFIPQNLTSFKNSTKSWVGFSG 301
Query: 501 GLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA 680
G H++ +D G+ +S G G+LG GA + P + L V VACGA A
Sbjct: 302 GQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPA--VSSVACGASVGYA 359
Query: 681 LTNSGDLYSW 710
+T G +++W
Sbjct: 360 VTKDGRVFAW 369
Score = 58.8 bits (136), Expect = 2e-08
Identities = 36/120 (30%), Positives = 57/120 (47%)
Frame = +3
Query: 351 HSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDE 530
H + + G + + G DVGQLG K PALV +D + G H++ + +
Sbjct: 27 HRSHSTEPGLVLTLGQGDVGQLGLGENVMERKKPALVSIPED--VVQAEAGGMHTVCLSK 84
Query: 531 WGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
GQ +S+G + G LG + + L K V+QV+ G H+ ALT+ G ++ W
Sbjct: 85 SGQVYSFGCNDEGALGRDTSVEGSEMVPGKVELQEK-VVQVSAGDSHTAALTDDGRVFLW 143
Score = 38.3 bits (85), Expect = 0.027
Identities = 37/142 (26%), Positives = 60/142 (42%), Gaps = 17/142 (11%)
Frame = +3
Query: 333 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTE--SDNGKNPALVETF-KDCTI------ 485
VA+G H + L+ G LY+ G + GQLGR E ++ G L C +
Sbjct: 177 VASGNDHLVMLTADGDLYTLGCGEQGQLGRVPELFANRGGRQGLERLLVPKCVMLKSRGS 236
Query: 486 ------STIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGL--ATKN 641
CG + AI G + +G + QLG G + P+ + +TK+
Sbjct: 237 RGHVRFQDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTP-GTESCFIPQNLTSFKNSTKS 295
Query: 642 VIQVACGAYHSVALTNSGDLYS 707
+ + G +H+V + + G YS
Sbjct: 296 WVGFSGGQHHTVCMDSEGKAYS 317
Score = 36.7 bits (81), Expect = 0.082
Identities = 21/69 (30%), Positives = 34/69 (49%)
Frame = +3
Query: 504 LQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVAL 683
+ H E G + G +GQLG LG + ++ K ++V+Q G H+V L
Sbjct: 25 VSHRSHSTEPGLVLTLGQGDVGQLG--LGENVMERKKPALVSIPEDVVQAEAGGMHTVCL 82
Query: 684 TNSGDLYSW 710
+ SG +YS+
Sbjct: 83 SKSGQVYSF 91
>X06130-1|CAA29496.1| 421|Homo sapiens protein ( Human mRNA for
cell cycle gene RCC1. ).
Length = 421
Score = 64.9 bits (151), Expect = 3e-10
Identities = 52/143 (36%), Positives = 73/143 (51%), Gaps = 3/143 (2%)
Frame = +3
Query: 288 KPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKN-PALVE 464
KP L E D +QA A G H++ LS SG +YS G ND G LGR T + + P VE
Sbjct: 59 KPALVSIPE-DVVQAEAGG-MHTVCLSKSGQVYSFGCNDEGALGRDTSVEGSEMVPGKVE 116
Query: 465 TFKDCTISTIACGLQHSLAIDEWGQPFSWGS--DSMGQLGNNLGAHAQDKPKFVKGLATK 638
+ + ++ G H+ A+ + G+ F WGS D+ G +G L + V+
Sbjct: 117 LQE--KVVQVSAGDSHTAALTDDGRVFLWGSFRDNNGVIG--LLEPMKKSMVPVQVQLDV 172
Query: 639 NVIQVACGAYHSVALTNSGDLYS 707
V++VA G H V LT GDLY+
Sbjct: 173 PVVKVASGNDHLVMLTADGDLYT 195
Score = 61.3 bits (142), Expect = 3e-09
Identities = 40/158 (25%), Positives = 75/158 (47%), Gaps = 2/158 (1%)
Frame = +3
Query: 216 MFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQA-VAAGEFHSLYLSNSGHLYSC 392
++ +G + +H+L G++ I L+ +K S + G+ H++ + + G YS
Sbjct: 261 VYGFGLSNYHQLGTPGTE--SCFIPQNLTSFKNSTKSWVGFSGGQHHTVCMDSEGKAYSL 318
Query: 393 GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQ 572
G + G+LG ++ P L+ +S++ACG A+ + G+ F+WG + Q
Sbjct: 319 GRAEYGRLGLGEGAEEKSIPTLISRLP--AVSSVACGASVGYAVTKDGRVFAWGMGTNYQ 376
Query: 573 LGNNLGAHAQDKPKFV-KGLATKNVIQVACGAYHSVAL 683
LG A + + K L + V+ V+ G H+V L
Sbjct: 377 LGTGQDEDAWSPVEMMGKQLENRVVLSVSSGGQHTVLL 414
Score = 59.3 bits (137), Expect = 1e-08
Identities = 38/130 (29%), Positives = 64/130 (49%), Gaps = 2/130 (1%)
Frame = +3
Query: 327 QAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIAC-- 500
Q G + + +S+ GH+Y G ++ QLG +++ P + +FK+ T S +
Sbjct: 243 QDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTPG-TESCFIPQNLTSFKNSTKSWVGFSG 301
Query: 501 GLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA 680
G H++ +D G+ +S G G+LG GA + P + L V VACGA A
Sbjct: 302 GQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPA--VSSVACGASVGYA 359
Query: 681 LTNSGDLYSW 710
+T G +++W
Sbjct: 360 VTKDGRVFAW 369
Score = 58.8 bits (136), Expect = 2e-08
Identities = 36/120 (30%), Positives = 57/120 (47%)
Frame = +3
Query: 351 HSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDE 530
H + + G + + G DVGQLG K PALV +D + G H++ + +
Sbjct: 27 HRSHSTEPGLVLTLGQGDVGQLGLGENVMERKKPALVSIPED--VVQAEAGGMHTVCLSK 84
Query: 531 WGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
GQ +S+G + G LG + + L K V+QV+ G H+ ALT+ G ++ W
Sbjct: 85 SGQVYSFGCNDEGALGRDTSVEGSEMVPGKVELQEK-VVQVSAGDSHTAALTDDGRVFLW 143
Score = 38.3 bits (85), Expect = 0.027
Identities = 37/142 (26%), Positives = 60/142 (42%), Gaps = 17/142 (11%)
Frame = +3
Query: 333 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTE--SDNGKNPALVETF-KDCTI------ 485
VA+G H + L+ G LY+ G + GQLGR E ++ G L C +
Sbjct: 177 VASGNDHLVMLTADGDLYTLGCGEQGQLGRVPELFANRGGRQGLERLLVPKCVMLKSRGS 236
Query: 486 ------STIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGL--ATKN 641
CG + AI G + +G + QLG G + P+ + +TK+
Sbjct: 237 RGHVRFQDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTP-GTESCFIPQNLTSFKNSTKS 295
Query: 642 VIQVACGAYHSVALTNSGDLYS 707
+ + G +H+V + + G YS
Sbjct: 296 WVGFSGGQHHTVCMDSEGKAYS 317
Score = 36.7 bits (81), Expect = 0.082
Identities = 21/69 (30%), Positives = 34/69 (49%)
Frame = +3
Query: 504 LQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVAL 683
+ H E G + G +GQLG LG + ++ K ++V+Q G H+V L
Sbjct: 25 VSHRSHSTEPGLVLTLGQGDVGQLG--LGENVMERKKPALVSIPEDVVQAEAGGMHTVCL 82
Query: 684 TNSGDLYSW 710
+ SG +YS+
Sbjct: 83 SKSGQVYSF 91
>D00591-1|BAA00469.1| 421|Homo sapiens RCC1 protein.
Length = 421
Score = 64.9 bits (151), Expect = 3e-10
Identities = 52/143 (36%), Positives = 73/143 (51%), Gaps = 3/143 (2%)
Frame = +3
Query: 288 KPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKN-PALVE 464
KP L E D +QA A G H++ LS SG +YS G ND G LGR T + + P VE
Sbjct: 59 KPALVSIPE-DVVQAEAGG-MHTVCLSKSGQVYSFGCNDEGALGRDTSVEGSEMVPGKVE 116
Query: 465 TFKDCTISTIACGLQHSLAIDEWGQPFSWGS--DSMGQLGNNLGAHAQDKPKFVKGLATK 638
+ + ++ G H+ A+ + G+ F WGS D+ G +G L + V+
Sbjct: 117 LQE--KVVQVSAGDSHTAALTDDGRVFLWGSFRDNNGVIG--LLEPMKKSMVPVQVQLDV 172
Query: 639 NVIQVACGAYHSVALTNSGDLYS 707
V++VA G H V LT GDLY+
Sbjct: 173 PVVKVASGNDHLVMLTADGDLYT 195
Score = 61.3 bits (142), Expect = 3e-09
Identities = 40/158 (25%), Positives = 75/158 (47%), Gaps = 2/158 (1%)
Frame = +3
Query: 216 MFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQA-VAAGEFHSLYLSNSGHLYSC 392
++ +G + +H+L G++ I L+ +K S + G+ H++ + + G YS
Sbjct: 261 VYGFGLSNYHQLGTPGTE--SCFIPQNLTSFKNSTKSWVGFSGGQHHTVCMDSEGKAYSL 318
Query: 393 GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQ 572
G + G+LG ++ P L+ +S++ACG A+ + G+ F+WG + Q
Sbjct: 319 GRAEYGRLGLGEGAEEKSIPTLISRLP--AVSSVACGASVGYAVTKDGRVFAWGMGTNYQ 376
Query: 573 LGNNLGAHAQDKPKFV-KGLATKNVIQVACGAYHSVAL 683
LG A + + K L + V+ V+ G H+V L
Sbjct: 377 LGTGQDEDAWSPVEMMGKQLENRVVLSVSSGGQHTVLL 414
Score = 59.3 bits (137), Expect = 1e-08
Identities = 38/130 (29%), Positives = 64/130 (49%), Gaps = 2/130 (1%)
Frame = +3
Query: 327 QAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIAC-- 500
Q G + + +S+ GH+Y G ++ QLG +++ P + +FK+ T S +
Sbjct: 243 QDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTPG-TESCFIPQNLTSFKNSTKSWVGFSG 301
Query: 501 GLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA 680
G H++ +D G+ +S G G+LG GA + P + L V VACGA A
Sbjct: 302 GQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPA--VSSVACGASVGYA 359
Query: 681 LTNSGDLYSW 710
+T G +++W
Sbjct: 360 VTKDGRVFAW 369
Score = 58.8 bits (136), Expect = 2e-08
Identities = 36/120 (30%), Positives = 57/120 (47%)
Frame = +3
Query: 351 HSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDE 530
H + + G + + G DVGQLG K PALV +D + G H++ + +
Sbjct: 27 HRSHSTEPGLVLTLGQGDVGQLGLGENVMERKKPALVSIPED--VVQAEAGGMHTVCLSK 84
Query: 531 WGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
GQ +S+G + G LG + + L K V+QV+ G H+ ALT+ G ++ W
Sbjct: 85 SGQVYSFGCNDEGALGRDTSVEGSEMVPGKVELQEK-VVQVSAGDSHTAALTDDGRVFLW 143
Score = 38.3 bits (85), Expect = 0.027
Identities = 37/142 (26%), Positives = 60/142 (42%), Gaps = 17/142 (11%)
Frame = +3
Query: 333 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTE--SDNGKNPALVETF-KDCTI------ 485
VA+G H + L+ G LY+ G + GQLGR E ++ G L C +
Sbjct: 177 VASGNDHLVMLTADGDLYTLGCGEQGQLGRVPELFANRGGRQGLERLLVPKCVMLKSRGS 236
Query: 486 ------STIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGL--ATKN 641
CG + AI G + +G + QLG G + P+ + +TK+
Sbjct: 237 RGHVRFQDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTP-GTESCFIPQNLTSFKNSTKS 295
Query: 642 VIQVACGAYHSVALTNSGDLYS 707
+ + G +H+V + + G YS
Sbjct: 296 WVGFSGGQHHTVCMDSEGKAYS 317
Score = 36.7 bits (81), Expect = 0.082
Identities = 21/69 (30%), Positives = 34/69 (49%)
Frame = +3
Query: 504 LQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVAL 683
+ H E G + G +GQLG LG + ++ K ++V+Q G H+V L
Sbjct: 25 VSHRSHSTEPGLVLTLGQGDVGQLG--LGENVMERKKPALVSIPEDVVQAEAGGMHTVCL 82
Query: 684 TNSGDLYSW 710
+ SG +YS+
Sbjct: 83 SKSGQVYSF 91
>CR407693-1|CAG28621.1| 421|Homo sapiens CHC1 protein.
Length = 421
Score = 64.9 bits (151), Expect = 3e-10
Identities = 52/143 (36%), Positives = 73/143 (51%), Gaps = 3/143 (2%)
Frame = +3
Query: 288 KPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKN-PALVE 464
KP L E D +QA A G H++ LS SG +YS G ND G LGR T + + P VE
Sbjct: 59 KPALVSIPE-DVVQAEAGG-MHTVCLSKSGQVYSFGCNDEGALGRDTSVEGSEMVPGKVE 116
Query: 465 TFKDCTISTIACGLQHSLAIDEWGQPFSWGS--DSMGQLGNNLGAHAQDKPKFVKGLATK 638
+ + ++ G H+ A+ + G+ F WGS D+ G +G L + V+
Sbjct: 117 LQE--KVVQVSAGDSHTAALTDDGRVFLWGSFRDNNGVIG--LLEPMKKSMVPVQVQLDV 172
Query: 639 NVIQVACGAYHSVALTNSGDLYS 707
V++VA G H V LT GDLY+
Sbjct: 173 PVVKVASGNDHLVMLTADGDLYT 195
Score = 61.3 bits (142), Expect = 3e-09
Identities = 40/158 (25%), Positives = 75/158 (47%), Gaps = 2/158 (1%)
Frame = +3
Query: 216 MFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQA-VAAGEFHSLYLSNSGHLYSC 392
++ +G + +H+L G++ I L+ +K S + G+ H++ + + G YS
Sbjct: 261 VYGFGLSNYHQLGTPGTE--SCFIPQNLTSFKNSTKSWVGFSGGQHHTVCMDSEGKAYSL 318
Query: 393 GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQ 572
G + G+LG ++ P L+ +S++ACG A+ + G+ F+WG + Q
Sbjct: 319 GRAEYGRLGLGEGAEEKSIPTLISRLP--AVSSVACGASVGYAVTKDGRVFAWGMGTNYQ 376
Query: 573 LGNNLGAHAQDKPKFV-KGLATKNVIQVACGAYHSVAL 683
LG A + + K L + V+ V+ G H+V L
Sbjct: 377 LGTGQDEDAWSPVEMMGKQLENRVVLSVSSGGQHTVLL 414
Score = 59.3 bits (137), Expect = 1e-08
Identities = 38/130 (29%), Positives = 64/130 (49%), Gaps = 2/130 (1%)
Frame = +3
Query: 327 QAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIAC-- 500
Q G + + +S+ GH+Y G ++ QLG +++ P + +FK+ T S +
Sbjct: 243 QDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTPG-TESCFIPQNLTSFKNSTKSWVGFSG 301
Query: 501 GLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA 680
G H++ +D G+ +S G G+LG GA + P + L V VACGA A
Sbjct: 302 GQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPA--VSSVACGASVGYA 359
Query: 681 LTNSGDLYSW 710
+T G +++W
Sbjct: 360 VTKDGRVFAW 369
Score = 58.8 bits (136), Expect = 2e-08
Identities = 36/120 (30%), Positives = 57/120 (47%)
Frame = +3
Query: 351 HSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDE 530
H + + G + + G DVGQLG K PALV +D + G H++ + +
Sbjct: 27 HRSHSTEPGLVLTLGQGDVGQLGLGENVMERKKPALVSIPED--VVQAEAGGMHTVCLSK 84
Query: 531 WGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
GQ +S+G + G LG + + L K V+QV+ G H+ ALT+ G ++ W
Sbjct: 85 SGQVYSFGCNDEGALGRDTSVEGSEMVPGKVELQEK-VVQVSAGDSHTAALTDDGRVFLW 143
Score = 38.3 bits (85), Expect = 0.027
Identities = 37/142 (26%), Positives = 60/142 (42%), Gaps = 17/142 (11%)
Frame = +3
Query: 333 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTE--SDNGKNPALVETF-KDCTI------ 485
VA+G H + L+ G LY+ G + GQLGR E ++ G L C +
Sbjct: 177 VASGNDHLVMLTADGDLYTLGCGEQGQLGRVPELFANRGGRQGLERLLVPKCVMLKSRGS 236
Query: 486 ------STIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGL--ATKN 641
CG + AI G + +G + QLG G + P+ + +TK+
Sbjct: 237 RGHVRFQDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTP-GTESCFIPQNLTSFKNSTKS 295
Query: 642 VIQVACGAYHSVALTNSGDLYS 707
+ + G +H+V + + G YS
Sbjct: 296 WVGFSGGQHHTVCMDSEGKAYS 317
Score = 36.7 bits (81), Expect = 0.082
Identities = 21/69 (30%), Positives = 34/69 (49%)
Frame = +3
Query: 504 LQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVAL 683
+ H E G + G +GQLG LG + ++ K ++V+Q G H+V L
Sbjct: 25 VSHRSHSTEPGLVLTLGQGDVGQLG--LGENVMERKKPALVSIPEDVVQAEAGGMHTVCL 82
Query: 684 TNSGDLYSW 710
+ SG +YS+
Sbjct: 83 SKSGQVYSF 91
>BC069198-1|AAH69198.1| 452|Homo sapiens regulator of chromosome
condensation 1 protein.
Length = 452
Score = 64.9 bits (151), Expect = 3e-10
Identities = 52/143 (36%), Positives = 73/143 (51%), Gaps = 3/143 (2%)
Frame = +3
Query: 288 KPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKN-PALVE 464
KP L E D +QA A G H++ LS SG +YS G ND G LGR T + + P VE
Sbjct: 90 KPALVSIPE-DVVQAEAGG-MHTVCLSKSGQVYSFGCNDEGALGRDTSVEGSEMVPGKVE 147
Query: 465 TFKDCTISTIACGLQHSLAIDEWGQPFSWGS--DSMGQLGNNLGAHAQDKPKFVKGLATK 638
+ + ++ G H+ A+ + G+ F WGS D+ G +G L + V+
Sbjct: 148 LQE--KVVQVSAGDSHTAALTDDGRVFLWGSFRDNNGVIG--LLEPMKKSMVPVQVQLDV 203
Query: 639 NVIQVACGAYHSVALTNSGDLYS 707
V++VA G H V LT GDLY+
Sbjct: 204 PVVKVASGNDHLVMLTADGDLYT 226
Score = 61.3 bits (142), Expect = 3e-09
Identities = 40/158 (25%), Positives = 75/158 (47%), Gaps = 2/158 (1%)
Frame = +3
Query: 216 MFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQA-VAAGEFHSLYLSNSGHLYSC 392
++ +G + +H+L G++ I L+ +K S + G+ H++ + + G YS
Sbjct: 292 VYGFGLSNYHQLGTPGTE--SCFIPQNLTSFKNSTKSWVGFSGGQHHTVCMDSEGKAYSL 349
Query: 393 GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQ 572
G + G+LG ++ P L+ +S++ACG A+ + G+ F+WG + Q
Sbjct: 350 GRAEYGRLGLGEGAEEKSIPTLISRLP--AVSSVACGASVGYAVTKDGRVFAWGMGTNYQ 407
Query: 573 LGNNLGAHAQDKPKFV-KGLATKNVIQVACGAYHSVAL 683
LG A + + K L + V+ V+ G H+V L
Sbjct: 408 LGTGQDEDAWSPVEMMGKQLENRVVLSVSSGGQHTVLL 445
Score = 59.3 bits (137), Expect = 1e-08
Identities = 38/130 (29%), Positives = 64/130 (49%), Gaps = 2/130 (1%)
Frame = +3
Query: 327 QAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIAC-- 500
Q G + + +S+ GH+Y G ++ QLG +++ P + +FK+ T S +
Sbjct: 274 QDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTPG-TESCFIPQNLTSFKNSTKSWVGFSG 332
Query: 501 GLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA 680
G H++ +D G+ +S G G+LG GA + P + L V VACGA A
Sbjct: 333 GQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPA--VSSVACGASVGYA 390
Query: 681 LTNSGDLYSW 710
+T G +++W
Sbjct: 391 VTKDGRVFAW 400
Score = 58.8 bits (136), Expect = 2e-08
Identities = 36/120 (30%), Positives = 57/120 (47%)
Frame = +3
Query: 351 HSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDE 530
H + + G + + G DVGQLG K PALV +D + G H++ + +
Sbjct: 58 HRSHSTEPGLVLTLGQGDVGQLGLGENVMERKKPALVSIPED--VVQAEAGGMHTVCLSK 115
Query: 531 WGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
GQ +S+G + G LG + + L K V+QV+ G H+ ALT+ G ++ W
Sbjct: 116 SGQVYSFGCNDEGALGRDTSVEGSEMVPGKVELQEK-VVQVSAGDSHTAALTDDGRVFLW 174
Score = 38.3 bits (85), Expect = 0.027
Identities = 37/142 (26%), Positives = 60/142 (42%), Gaps = 17/142 (11%)
Frame = +3
Query: 333 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTE--SDNGKNPALVETF-KDCTI------ 485
VA+G H + L+ G LY+ G + GQLGR E ++ G L C +
Sbjct: 208 VASGNDHLVMLTADGDLYTLGCGEQGQLGRVPELFANRGGRQGLERLLVPKCVMLKSRGS 267
Query: 486 ------STIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGL--ATKN 641
CG + AI G + +G + QLG G + P+ + +TK+
Sbjct: 268 RGHVRFQDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTP-GTESCFIPQNLTSFKNSTKS 326
Query: 642 VIQVACGAYHSVALTNSGDLYS 707
+ + G +H+V + + G YS
Sbjct: 327 WVGFSGGQHHTVCMDSEGKAYS 348
Score = 36.7 bits (81), Expect = 0.082
Identities = 21/69 (30%), Positives = 34/69 (49%)
Frame = +3
Query: 504 LQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVAL 683
+ H E G + G +GQLG LG + ++ K ++V+Q G H+V L
Sbjct: 56 VSHRSHSTEPGLVLTLGQGDVGQLG--LGENVMERKKPALVSIPEDVVQAEAGGMHTVCL 113
Query: 684 TNSGDLYSW 710
+ SG +YS+
Sbjct: 114 SKSGQVYSF 122
>BC036903-1|AAH36903.1| 421|Homo sapiens regulator of chromosome
condensation 1 protein.
Length = 421
Score = 64.9 bits (151), Expect = 3e-10
Identities = 52/143 (36%), Positives = 73/143 (51%), Gaps = 3/143 (2%)
Frame = +3
Query: 288 KPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKN-PALVE 464
KP L E D +QA A G H++ LS SG +YS G ND G LGR T + + P VE
Sbjct: 59 KPALVSIPE-DVVQAEAGG-MHTVCLSKSGQVYSFGCNDEGALGRDTSVEGSEMVPGKVE 116
Query: 465 TFKDCTISTIACGLQHSLAIDEWGQPFSWGS--DSMGQLGNNLGAHAQDKPKFVKGLATK 638
+ + ++ G H+ A+ + G+ F WGS D+ G +G L + V+
Sbjct: 117 LQE--KVVQVSAGDSHTAALTDDGRVFLWGSFRDNNGVIG--LLEPMKKSMVPVQVQLDV 172
Query: 639 NVIQVACGAYHSVALTNSGDLYS 707
V++VA G H V LT GDLY+
Sbjct: 173 PVVKVASGNDHLVMLTADGDLYT 195
Score = 61.3 bits (142), Expect = 3e-09
Identities = 40/158 (25%), Positives = 75/158 (47%), Gaps = 2/158 (1%)
Frame = +3
Query: 216 MFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQA-VAAGEFHSLYLSNSGHLYSC 392
++ +G + +H+L G++ I L+ +K S + G+ H++ + + G YS
Sbjct: 261 VYGFGLSNYHQLGTPGTE--SCFIPQNLTSFKNSTKSWVGFSGGQHHTVCMDSEGKAYSL 318
Query: 393 GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQ 572
G + G+LG ++ P L+ +S++ACG A+ + G+ F+WG + Q
Sbjct: 319 GRAEYGRLGLGEGAEEKSIPTLISRLP--AVSSVACGASVGYAVTKDGRVFAWGMGTNYQ 376
Query: 573 LGNNLGAHAQDKPKFV-KGLATKNVIQVACGAYHSVAL 683
LG A + + K L + V+ V+ G H+V L
Sbjct: 377 LGTGQDEDAWSPVEMMGKQLENRVVLSVSSGGQHTVLL 414
Score = 59.3 bits (137), Expect = 1e-08
Identities = 38/130 (29%), Positives = 64/130 (49%), Gaps = 2/130 (1%)
Frame = +3
Query: 327 QAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIAC-- 500
Q G + + +S+ GH+Y G ++ QLG +++ P + +FK+ T S +
Sbjct: 243 QDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTPG-TESCFIPQNLTSFKNSTKSWVGFSG 301
Query: 501 GLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA 680
G H++ +D G+ +S G G+LG GA + P + L V VACGA A
Sbjct: 302 GQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPA--VSSVACGASVGYA 359
Query: 681 LTNSGDLYSW 710
+T G +++W
Sbjct: 360 VTKDGRVFAW 369
Score = 58.8 bits (136), Expect = 2e-08
Identities = 36/120 (30%), Positives = 57/120 (47%)
Frame = +3
Query: 351 HSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDE 530
H + + G + + G DVGQLG K PALV +D + G H++ + +
Sbjct: 27 HRSHSTEPGLVLTLGQGDVGQLGLGENVMERKKPALVSIPED--VVQAEAGGMHTVCLSK 84
Query: 531 WGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
GQ +S+G + G LG + + L K V+QV+ G H+ ALT+ G ++ W
Sbjct: 85 SGQVYSFGCNDEGALGRDTSVEGSEMVPGKVELQEK-VVQVSAGDSHTAALTDDGRVFLW 143
Score = 38.3 bits (85), Expect = 0.027
Identities = 37/142 (26%), Positives = 60/142 (42%), Gaps = 17/142 (11%)
Frame = +3
Query: 333 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTE--SDNGKNPALVETF-KDCTI------ 485
VA+G H + L+ G LY+ G + GQLGR E ++ G L C +
Sbjct: 177 VASGNDHLVMLTADGDLYTLGCGEQGQLGRVPELFANRGGRQGLERLLVPKCVMLKSRGS 236
Query: 486 ------STIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGL--ATKN 641
CG + AI G + +G + QLG G + P+ + +TK+
Sbjct: 237 RGHVRFQDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTP-GTESCFIPQNLTSFKNSTKS 295
Query: 642 VIQVACGAYHSVALTNSGDLYS 707
+ + G +H+V + + G YS
Sbjct: 296 WVGFSGGQHHTVCMDSEGKAYS 317
Score = 36.7 bits (81), Expect = 0.082
Identities = 21/69 (30%), Positives = 34/69 (49%)
Frame = +3
Query: 504 LQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVAL 683
+ H E G + G +GQLG LG + ++ K ++V+Q G H+V L
Sbjct: 25 VSHRSHSTEPGLVLTLGQGDVGQLG--LGENVMERKKPALVSIPEDVVQAEAGGMHTVCL 82
Query: 684 TNSGDLYSW 710
+ SG +YS+
Sbjct: 83 SKSGQVYSF 91
>BC010067-1|AAH10067.1| 421|Homo sapiens regulator of chromosome
condensation 1 protein.
Length = 421
Score = 64.9 bits (151), Expect = 3e-10
Identities = 52/143 (36%), Positives = 73/143 (51%), Gaps = 3/143 (2%)
Frame = +3
Query: 288 KPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKN-PALVE 464
KP L E D +QA A G H++ LS SG +YS G ND G LGR T + + P VE
Sbjct: 59 KPALVSIPE-DVVQAEAGG-MHTVCLSKSGQVYSFGCNDEGALGRDTSVEGSEMVPGKVE 116
Query: 465 TFKDCTISTIACGLQHSLAIDEWGQPFSWGS--DSMGQLGNNLGAHAQDKPKFVKGLATK 638
+ + ++ G H+ A+ + G+ F WGS D+ G +G L + V+
Sbjct: 117 LQE--KVVQVSAGDSHTAALTDDGRVFLWGSFRDNNGVIG--LLEPMKKSMVPVQVQLDV 172
Query: 639 NVIQVACGAYHSVALTNSGDLYS 707
V++VA G H V LT GDLY+
Sbjct: 173 PVVKVASGNDHLVMLTADGDLYT 195
Score = 61.3 bits (142), Expect = 3e-09
Identities = 40/158 (25%), Positives = 75/158 (47%), Gaps = 2/158 (1%)
Frame = +3
Query: 216 MFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQA-VAAGEFHSLYLSNSGHLYSC 392
++ +G + +H+L G++ I L+ +K S + G+ H++ + + G YS
Sbjct: 261 VYGFGLSNYHQLGTPGTE--SCFIPQNLTSFKNSTKSWVGFSGGQHHTVCMDSEGKAYSL 318
Query: 393 GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQ 572
G + G+LG ++ P L+ +S++ACG A+ + G+ F+WG + Q
Sbjct: 319 GRAEYGRLGLGEGAEEKSIPTLISRLP--AVSSVACGASVGYAVTKDGRVFAWGMGTNYQ 376
Query: 573 LGNNLGAHAQDKPKFV-KGLATKNVIQVACGAYHSVAL 683
LG A + + K L + V+ V+ G H+V L
Sbjct: 377 LGTGQDEDAWSPVEMMGKQLENRVVLSVSSGGQHTVLL 414
Score = 59.3 bits (137), Expect = 1e-08
Identities = 38/130 (29%), Positives = 64/130 (49%), Gaps = 2/130 (1%)
Frame = +3
Query: 327 QAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIAC-- 500
Q G + + +S+ GH+Y G ++ QLG +++ P + +FK+ T S +
Sbjct: 243 QDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTPG-TESCFIPQNLTSFKNSTKSWVGFSG 301
Query: 501 GLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA 680
G H++ +D G+ +S G G+LG GA + P + L V VACGA A
Sbjct: 302 GQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPA--VSSVACGASVGYA 359
Query: 681 LTNSGDLYSW 710
+T G +++W
Sbjct: 360 VTKDGRVFAW 369
Score = 58.8 bits (136), Expect = 2e-08
Identities = 36/120 (30%), Positives = 57/120 (47%)
Frame = +3
Query: 351 HSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDE 530
H + + G + + G DVGQLG K PALV +D + G H++ + +
Sbjct: 27 HRSHSTEPGLVLTLGQGDVGQLGLGENVMERKKPALVSIPED--VVQAEAGGMHTVCLSK 84
Query: 531 WGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
GQ +S+G + G LG + + L K V+QV+ G H+ ALT+ G ++ W
Sbjct: 85 SGQVYSFGCNDEGALGRDTSVEGSEMVPGKVELQEK-VVQVSAGDSHTAALTDDGRVFLW 143
Score = 38.3 bits (85), Expect = 0.027
Identities = 37/142 (26%), Positives = 60/142 (42%), Gaps = 17/142 (11%)
Frame = +3
Query: 333 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTE--SDNGKNPALVETF-KDCTI------ 485
VA+G H + L+ G LY+ G + GQLGR E ++ G L C +
Sbjct: 177 VASGNDHLVMLTADGDLYTLGCGEQGQLGRVPELFANRGGRQGLERLLVPKCVMLKSRGS 236
Query: 486 ------STIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGL--ATKN 641
CG + AI G + +G + QLG G + P+ + +TK+
Sbjct: 237 RGHVRFQDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTP-GTESCFIPQNLTSFKNSTKS 295
Query: 642 VIQVACGAYHSVALTNSGDLYS 707
+ + G +H+V + + G YS
Sbjct: 296 WVGFSGGQHHTVCMDSEGKAYS 317
Score = 36.7 bits (81), Expect = 0.082
Identities = 21/69 (30%), Positives = 34/69 (49%)
Frame = +3
Query: 504 LQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVAL 683
+ H E G + G +GQLG LG + ++ K ++V+Q G H+V L
Sbjct: 25 VSHRSHSTEPGLVLTLGQGDVGQLG--LGENVMERKKPALVSIPEDVVQAEAGGMHTVCL 82
Query: 684 TNSGDLYSW 710
+ SG +YS+
Sbjct: 83 SKSGQVYSF 91
>BC007300-1|AAH07300.1| 421|Homo sapiens regulator of chromosome
condensation 1 protein.
Length = 421
Score = 64.9 bits (151), Expect = 3e-10
Identities = 52/143 (36%), Positives = 73/143 (51%), Gaps = 3/143 (2%)
Frame = +3
Query: 288 KPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKN-PALVE 464
KP L E D +QA A G H++ LS SG +YS G ND G LGR T + + P VE
Sbjct: 59 KPALVSIPE-DVVQAEAGG-MHTVCLSKSGQVYSFGCNDEGALGRDTSVEGSEMVPGKVE 116
Query: 465 TFKDCTISTIACGLQHSLAIDEWGQPFSWGS--DSMGQLGNNLGAHAQDKPKFVKGLATK 638
+ + ++ G H+ A+ + G+ F WGS D+ G +G L + V+
Sbjct: 117 LQE--KVVQVSAGDSHTAALTDDGRVFLWGSFRDNNGVIG--LLEPMKKSMVPVQVQLDV 172
Query: 639 NVIQVACGAYHSVALTNSGDLYS 707
V++VA G H V LT GDLY+
Sbjct: 173 PVVKVASGNDHLVMLTADGDLYT 195
Score = 61.3 bits (142), Expect = 3e-09
Identities = 40/158 (25%), Positives = 75/158 (47%), Gaps = 2/158 (1%)
Frame = +3
Query: 216 MFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQA-VAAGEFHSLYLSNSGHLYSC 392
++ +G + +H+L G++ I L+ +K S + G+ H++ + + G YS
Sbjct: 261 VYGFGLSNYHQLGTPGTE--SCFIPQNLTSFKNSTKSWVGFSGGQHHTVCMDSEGKAYSL 318
Query: 393 GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQ 572
G + G+LG ++ P L+ +S++ACG A+ + G+ F+WG + Q
Sbjct: 319 GRAEYGRLGLGEGAEEKSIPTLISRLP--AVSSVACGASVGYAVTKDGRVFAWGMGTNYQ 376
Query: 573 LGNNLGAHAQDKPKFV-KGLATKNVIQVACGAYHSVAL 683
LG A + + K L + V+ V+ G H+V L
Sbjct: 377 LGTGQDEDAWSPVEMMGKQLENRVVLSVSSGGQHTVLL 414
Score = 59.3 bits (137), Expect = 1e-08
Identities = 38/130 (29%), Positives = 64/130 (49%), Gaps = 2/130 (1%)
Frame = +3
Query: 327 QAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIAC-- 500
Q G + + +S+ GH+Y G ++ QLG +++ P + +FK+ T S +
Sbjct: 243 QDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTPG-TESCFIPQNLTSFKNSTKSWVGFSG 301
Query: 501 GLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA 680
G H++ +D G+ +S G G+LG GA + P + L V VACGA A
Sbjct: 302 GQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPA--VSSVACGASVGYA 359
Query: 681 LTNSGDLYSW 710
+T G +++W
Sbjct: 360 VTKDGRVFAW 369
Score = 58.8 bits (136), Expect = 2e-08
Identities = 36/120 (30%), Positives = 57/120 (47%)
Frame = +3
Query: 351 HSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDE 530
H + + G + + G DVGQLG K PALV +D + G H++ + +
Sbjct: 27 HRSHSTEPGLVLTLGQGDVGQLGLGENVMERKKPALVSIPED--VVQAEAGGMHTVCLSK 84
Query: 531 WGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
GQ +S+G + G LG + + L K V+QV+ G H+ ALT+ G ++ W
Sbjct: 85 SGQVYSFGCNDEGALGRDTSVEGSEMVPGKVELQEK-VVQVSAGDSHTAALTDDGRVFLW 143
Score = 38.3 bits (85), Expect = 0.027
Identities = 37/142 (26%), Positives = 60/142 (42%), Gaps = 17/142 (11%)
Frame = +3
Query: 333 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTE--SDNGKNPALVETF-KDCTI------ 485
VA+G H + L+ G LY+ G + GQLGR E ++ G L C +
Sbjct: 177 VASGNDHLVMLTADGDLYTLGCGEQGQLGRVPELFANRGGRQGLERLLVPKCVMLKSRGS 236
Query: 486 ------STIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGL--ATKN 641
CG + AI G + +G + QLG G + P+ + +TK+
Sbjct: 237 RGHVRFQDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTP-GTESCFIPQNLTSFKNSTKS 295
Query: 642 VIQVACGAYHSVALTNSGDLYS 707
+ + G +H+V + + G YS
Sbjct: 296 WVGFSGGQHHTVCMDSEGKAYS 317
Score = 36.7 bits (81), Expect = 0.082
Identities = 21/69 (30%), Positives = 34/69 (49%)
Frame = +3
Query: 504 LQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVAL 683
+ H E G + G +GQLG LG + ++ K ++V+Q G H+V L
Sbjct: 25 VSHRSHSTEPGLVLTLGQGDVGQLG--LGENVMERKKPALVSIPEDVVQAEAGGMHTVCL 82
Query: 684 TNSGDLYSW 710
+ SG +YS+
Sbjct: 83 SKSGQVYSF 91
>AL513497-2|CAI22287.1| 421|Homo sapiens regulator of chromosome
condensation 1 protein.
Length = 421
Score = 64.9 bits (151), Expect = 3e-10
Identities = 52/143 (36%), Positives = 73/143 (51%), Gaps = 3/143 (2%)
Frame = +3
Query: 288 KPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKN-PALVE 464
KP L E D +QA A G H++ LS SG +YS G ND G LGR T + + P VE
Sbjct: 59 KPALVSIPE-DVVQAEAGG-MHTVCLSKSGQVYSFGCNDEGALGRDTSVEGSEMVPGKVE 116
Query: 465 TFKDCTISTIACGLQHSLAIDEWGQPFSWGS--DSMGQLGNNLGAHAQDKPKFVKGLATK 638
+ + ++ G H+ A+ + G+ F WGS D+ G +G L + V+
Sbjct: 117 LQE--KVVQVSAGDSHTAALTDDGRVFLWGSFRDNNGVIG--LLEPMKKSMVPVQVQLDV 172
Query: 639 NVIQVACGAYHSVALTNSGDLYS 707
V++VA G H V LT GDLY+
Sbjct: 173 PVVKVASGNDHLVMLTADGDLYT 195
Score = 61.3 bits (142), Expect = 3e-09
Identities = 40/158 (25%), Positives = 75/158 (47%), Gaps = 2/158 (1%)
Frame = +3
Query: 216 MFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQA-VAAGEFHSLYLSNSGHLYSC 392
++ +G + +H+L G++ I L+ +K S + G+ H++ + + G YS
Sbjct: 261 VYGFGLSNYHQLGTPGTE--SCFIPQNLTSFKNSTKSWVGFSGGQHHTVCMDSEGKAYSL 318
Query: 393 GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQ 572
G + G+LG ++ P L+ +S++ACG A+ + G+ F+WG + Q
Sbjct: 319 GRAEYGRLGLGEGAEEKSIPTLISRLP--AVSSVACGASVGYAVTKDGRVFAWGMGTNYQ 376
Query: 573 LGNNLGAHAQDKPKFV-KGLATKNVIQVACGAYHSVAL 683
LG A + + K L + V+ V+ G H+V L
Sbjct: 377 LGTGQDEDAWSPVEMMGKQLENRVVLSVSSGGQHTVLL 414
Score = 59.3 bits (137), Expect = 1e-08
Identities = 38/130 (29%), Positives = 64/130 (49%), Gaps = 2/130 (1%)
Frame = +3
Query: 327 QAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIAC-- 500
Q G + + +S+ GH+Y G ++ QLG +++ P + +FK+ T S +
Sbjct: 243 QDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTPG-TESCFIPQNLTSFKNSTKSWVGFSG 301
Query: 501 GLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA 680
G H++ +D G+ +S G G+LG GA + P + L V VACGA A
Sbjct: 302 GQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPA--VSSVACGASVGYA 359
Query: 681 LTNSGDLYSW 710
+T G +++W
Sbjct: 360 VTKDGRVFAW 369
Score = 58.8 bits (136), Expect = 2e-08
Identities = 36/120 (30%), Positives = 57/120 (47%)
Frame = +3
Query: 351 HSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDE 530
H + + G + + G DVGQLG K PALV +D + G H++ + +
Sbjct: 27 HRSHSTEPGLVLTLGQGDVGQLGLGENVMERKKPALVSIPED--VVQAEAGGMHTVCLSK 84
Query: 531 WGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
GQ +S+G + G LG + + L K V+QV+ G H+ ALT+ G ++ W
Sbjct: 85 SGQVYSFGCNDEGALGRDTSVEGSEMVPGKVELQEK-VVQVSAGDSHTAALTDDGRVFLW 143
Score = 38.3 bits (85), Expect = 0.027
Identities = 37/142 (26%), Positives = 60/142 (42%), Gaps = 17/142 (11%)
Frame = +3
Query: 333 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTE--SDNGKNPALVETF-KDCTI------ 485
VA+G H + L+ G LY+ G + GQLGR E ++ G L C +
Sbjct: 177 VASGNDHLVMLTADGDLYTLGCGEQGQLGRVPELFANRGGRQGLERLLVPKCVMLKSRGS 236
Query: 486 ------STIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGL--ATKN 641
CG + AI G + +G + QLG G + P+ + +TK+
Sbjct: 237 RGHVRFQDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTP-GTESCFIPQNLTSFKNSTKS 295
Query: 642 VIQVACGAYHSVALTNSGDLYS 707
+ + G +H+V + + G YS
Sbjct: 296 WVGFSGGQHHTVCMDSEGKAYS 317
Score = 36.7 bits (81), Expect = 0.082
Identities = 21/69 (30%), Positives = 34/69 (49%)
Frame = +3
Query: 504 LQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVAL 683
+ H E G + G +GQLG LG + ++ K ++V+Q G H+V L
Sbjct: 25 VSHRSHSTEPGLVLTLGQGDVGQLG--LGENVMERKKPALVSIPEDVVQAEAGGMHTVCL 82
Query: 684 TNSGDLYSW 710
+ SG +YS+
Sbjct: 83 SKSGQVYSF 91
>AF498924-1|AAM21072.1| 421|Homo sapiens regulator of chromosome
condensation 1 protein.
Length = 421
Score = 64.9 bits (151), Expect = 3e-10
Identities = 52/143 (36%), Positives = 73/143 (51%), Gaps = 3/143 (2%)
Frame = +3
Query: 288 KPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKN-PALVE 464
KP L E D +QA A G H++ LS SG +YS G ND G LGR T + + P VE
Sbjct: 59 KPALVSIPE-DVVQAEAGG-MHTVCLSKSGQVYSFGCNDEGALGRDTSVEGSEMVPGKVE 116
Query: 465 TFKDCTISTIACGLQHSLAIDEWGQPFSWGS--DSMGQLGNNLGAHAQDKPKFVKGLATK 638
+ + ++ G H+ A+ + G+ F WGS D+ G +G L + V+
Sbjct: 117 LQE--KVVQVSAGDSHTAALTDDGRVFLWGSFRDNNGVIG--LLEPMKKSMVPVQVQLDV 172
Query: 639 NVIQVACGAYHSVALTNSGDLYS 707
V++VA G H V LT GDLY+
Sbjct: 173 PVVKVASGNDHLVMLTADGDLYT 195
Score = 61.3 bits (142), Expect = 3e-09
Identities = 40/158 (25%), Positives = 75/158 (47%), Gaps = 2/158 (1%)
Frame = +3
Query: 216 MFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQA-VAAGEFHSLYLSNSGHLYSC 392
++ +G + +H+L G++ I L+ +K S + G+ H++ + + G YS
Sbjct: 261 VYGFGLSNYHQLGTPGTE--SCFIPQNLTSFKNSTKSWVGFSGGQHHTVCMDSEGKAYSL 318
Query: 393 GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQ 572
G + G+LG ++ P L+ +S++ACG A+ + G+ F+WG + Q
Sbjct: 319 GRAEYGRLGLGEGAEEKSIPTLISRLP--AVSSVACGASVGYAVTKDGRVFAWGMGTNYQ 376
Query: 573 LGNNLGAHAQDKPKFV-KGLATKNVIQVACGAYHSVAL 683
LG A + + K L + V+ V+ G H+V L
Sbjct: 377 LGTGQDEDAWSPVEMMGKQLENRVVLSVSSGGQHTVLL 414
Score = 59.3 bits (137), Expect = 1e-08
Identities = 38/130 (29%), Positives = 64/130 (49%), Gaps = 2/130 (1%)
Frame = +3
Query: 327 QAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIAC-- 500
Q G + + +S+ GH+Y G ++ QLG +++ P + +FK+ T S +
Sbjct: 243 QDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTPG-TESCFIPQNLTSFKNSTKSWVGFSG 301
Query: 501 GLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA 680
G H++ +D G+ +S G G+LG GA + P + L V VACGA A
Sbjct: 302 GQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKSIPTLISRLPA--VSSVACGASVGYA 359
Query: 681 LTNSGDLYSW 710
+T G +++W
Sbjct: 360 VTKDGRVFAW 369
Score = 58.8 bits (136), Expect = 2e-08
Identities = 36/120 (30%), Positives = 57/120 (47%)
Frame = +3
Query: 351 HSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDE 530
H + + G + + G DVGQLG K PALV +D + G H++ + +
Sbjct: 27 HRSHSTEPGLVLTLGQGDVGQLGLGENVMERKKPALVSIPED--VVQAEAGGMHTVCLSK 84
Query: 531 WGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
GQ +S+G + G LG + + L K V+QV+ G H+ ALT+ G ++ W
Sbjct: 85 SGQVYSFGCNDEGALGRDTSVEGSEMVPGKVELQEK-VVQVSAGDSHTAALTDDGRVFLW 143
Score = 38.3 bits (85), Expect = 0.027
Identities = 37/142 (26%), Positives = 60/142 (42%), Gaps = 17/142 (11%)
Frame = +3
Query: 333 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTE--SDNGKNPALVETF-KDCTI------ 485
VA+G H + L+ G LY+ G + GQLGR E ++ G L C +
Sbjct: 177 VASGNDHLVMLTADGDLYTLGCGEQGQLGRVPELFANRGGRQGLERLLVPKCVMLKSRGS 236
Query: 486 ------STIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGL--ATKN 641
CG + AI G + +G + QLG G + P+ + +TK+
Sbjct: 237 RGHVRFQDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTP-GTESCFIPQNLTSFKNSTKS 295
Query: 642 VIQVACGAYHSVALTNSGDLYS 707
+ + G +H+V + + G YS
Sbjct: 296 WVGFSGGQHHTVCMDSEGKAYS 317
Score = 36.7 bits (81), Expect = 0.082
Identities = 21/69 (30%), Positives = 34/69 (49%)
Frame = +3
Query: 504 LQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVAL 683
+ H E G + G +GQLG LG + ++ K ++V+Q G H+V L
Sbjct: 25 VSHRSHSTEPGLVLTLGQGDVGQLG--LGENVMERKKPALVSIPEDVVQAEAGGMHTVCL 82
Query: 684 TNSGDLYSW 710
+ SG +YS+
Sbjct: 83 SKSGQVYSF 91
>BC040695-1|AAH40695.1| 358|Homo sapiens WBSCR16 protein protein.
Length = 358
Score = 62.1 bits (144), Expect = 2e-09
Identities = 42/136 (30%), Positives = 64/136 (47%), Gaps = 3/136 (2%)
Frame = +3
Query: 312 ESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQ-TESDNGKNPALVETFKDC--T 482
+ + V+ G HSL L++ ++S GNN GQ GR+ E++ V +D
Sbjct: 172 QETRVLQVSCGRAHSLVLTDREGVFSMGNNSYGQCGRKVVENEIYSESHRVHRMQDFDGQ 231
Query: 483 ISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACG 662
+ +ACG HSL + + G+ +S G + GQ G K LA NVIQVA
Sbjct: 232 VVQVACGQDHSLFLTDKGEVYSCGWGADGQTGLGHYNITSSPTKLGGDLAGVNVIQVATY 291
Query: 663 AYHSVALTNSGDLYSW 710
+A++ G L+ W
Sbjct: 292 GDCCLAVSADGGLFGW 307
Score = 46.8 bits (106), Expect = 8e-05
Identities = 32/120 (26%), Positives = 49/120 (40%)
Frame = +3
Query: 333 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQH 512
VA G+ HSL+L++ G +YSCG GQ G + L + +A
Sbjct: 235 VACGQDHSLFLTDKGEVYSCGWGADGQTGLGHYNITSSPTKLGGDLAGVNVIQVATYGDC 294
Query: 513 SLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNS 692
LA+ G F WG+ QL + + + P+ + V Q ACG L ++
Sbjct: 295 CLAVSADGGLFGWGNSEYLQLASVTDSTQVNVPRCLHFSGVGKVRQAACGGTGCAVLNDT 354
>BC032712-1|AAH32712.1| 454|Homo sapiens WBSCR16 protein protein.
Length = 454
Score = 62.1 bits (144), Expect = 2e-09
Identities = 42/136 (30%), Positives = 64/136 (47%), Gaps = 3/136 (2%)
Frame = +3
Query: 312 ESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQ-TESDNGKNPALVETFKDC--T 482
+ + V+ G HSL L++ ++S GNN GQ GR+ E++ V +D
Sbjct: 172 QETRVLQVSCGRAHSLVLTDREGVFSMGNNSYGQCGRKVVENEIYSESHRVHRMQDFDGQ 231
Query: 483 ISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACG 662
+ +ACG HSL + + G+ +S G + GQ G K LA NVIQVA
Sbjct: 232 VVQVACGQDHSLFLTDKGEVYSCGWGADGQTGLGHYNITSSPTKLGGDLAGVNVIQVATY 291
Query: 663 AYHSVALTNSGDLYSW 710
+A++ G L+ W
Sbjct: 292 GDCCLAVSADGGLFGW 307
Score = 53.2 bits (122), Expect = 9e-07
Identities = 34/126 (26%), Positives = 51/126 (40%)
Frame = +3
Query: 333 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQH 512
VA G+ HSL+L++ G +YSCG GQ G + L + +A
Sbjct: 235 VACGQDHSLFLTDKGEVYSCGWGADGQTGLGHYNITSSPTKLGGDLAGVNVIQVATYGDC 294
Query: 513 SLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNS 692
LA+ G F WG+ QL + + + P+ + V Q ACG L
Sbjct: 295 CLAVSADGGLFGWGNSEYLQLASVTDSTQVNVPRCLHFSGVGKVRQAACGGTGCAVLNGE 354
Query: 693 GDLYSW 710
G ++ W
Sbjct: 355 GHVFVW 360
Score = 50.4 bits (115), Expect = 6e-06
Identities = 41/135 (30%), Positives = 59/135 (43%), Gaps = 6/135 (4%)
Frame = +3
Query: 324 IQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACG 503
IQ G+ L +S G L+ GN++ QL T+S P + + ACG
Sbjct: 286 IQVATYGDC-CLAVSADGGLFGWGNSEYLQLASVTDSTQVNVPRCLHFSGVGKVRQAACG 344
Query: 504 LQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDK--PKFVKGLATKN----VIQVACGA 665
++ G F WG +G+ G NL A + P + GL N V ++ CG
Sbjct: 345 GTGCAVLNGEGHVFVWGYGILGK-GPNLVESAVPEMIPPTLFGLTEFNPEIQVSRIRCGL 403
Query: 666 YHSVALTNSGDLYSW 710
H ALTN G+L+ W
Sbjct: 404 SHFAALTNKGELFVW 418
Score = 40.7 bits (91), Expect = 0.005
Identities = 34/128 (26%), Positives = 54/128 (42%), Gaps = 7/128 (5%)
Frame = +3
Query: 216 MFCWGNATHHELC--IDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYS 389
+F WGN+ + +L D +Q+ P + ++ A G L+ GH++
Sbjct: 304 LFGWGNSEYLQLASVTDSTQVN----VPRCLHFSGVGKVRQAACGGTGCAVLNGEGHVFV 359
Query: 390 CGNNDVGQLGRQTESDNGKN--PAL---VETFKDCTISTIACGLQHSLAIDEWGQPFSWG 554
G +G+ ES + P L E + +S I CGL H A+ G+ F WG
Sbjct: 360 WGYGILGKGPNLVESAVPEMIPPTLFGLTEFNPEIQVSRIRCGLSHFAALTNKGELFVWG 419
Query: 555 SDSMGQLG 578
+ G LG
Sbjct: 420 KNIRGCLG 427
>BC019008-1|AAH19008.1| 464|Homo sapiens Williams-Beuren syndrome
chromosome region 16 protein.
Length = 464
Score = 62.1 bits (144), Expect = 2e-09
Identities = 42/136 (30%), Positives = 64/136 (47%), Gaps = 3/136 (2%)
Frame = +3
Query: 312 ESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQ-TESDNGKNPALVETFKDC--T 482
+ + V+ G HSL L++ ++S GNN GQ GR+ E++ V +D
Sbjct: 172 QETRVLQVSCGRAHSLVLTDREGVFSMGNNSYGQCGRKVVENEIYSESHRVHRMQDFDGQ 231
Query: 483 ISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACG 662
+ +ACG HSL + + G+ +S G + GQ G K LA NVIQVA
Sbjct: 232 VVQVACGQDHSLFLTDKGEVYSCGWGADGQTGLGHYNITSSPTKLGGDLAGVNVIQVATY 291
Query: 663 AYHSVALTNSGDLYSW 710
+A++ G L+ W
Sbjct: 292 GDCCLAVSADGGLFGW 307
Score = 53.2 bits (122), Expect = 9e-07
Identities = 34/126 (26%), Positives = 51/126 (40%)
Frame = +3
Query: 333 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQH 512
VA G+ HSL+L++ G +YSCG GQ G + L + +A
Sbjct: 235 VACGQDHSLFLTDKGEVYSCGWGADGQTGLGHYNITSSPTKLGGDLAGVNVIQVATYGDC 294
Query: 513 SLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNS 692
LA+ G F WG+ QL + + + P+ + V Q ACG L
Sbjct: 295 CLAVSADGGLFGWGNSEYLQLASVTDSTQVNVPRCLHFSGVGKVRQAACGGTGCAVLNGE 354
Query: 693 GDLYSW 710
G ++ W
Sbjct: 355 GHVFVW 360
Score = 50.4 bits (115), Expect = 6e-06
Identities = 41/135 (30%), Positives = 59/135 (43%), Gaps = 6/135 (4%)
Frame = +3
Query: 324 IQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACG 503
IQ G+ L +S G L+ GN++ QL T+S P + + ACG
Sbjct: 286 IQVATYGDC-CLAVSADGGLFGWGNSEYLQLASVTDSTQVNVPRCLHFSGVGKVRQAACG 344
Query: 504 LQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDK--PKFVKGLATKN----VIQVACGA 665
++ G F WG +G+ G NL A + P + GL N V ++ CG
Sbjct: 345 GTGCAVLNGEGHVFVWGYGILGK-GPNLVESAVPEMIPPTLFGLTEFNPEIQVSRIRCGL 403
Query: 666 YHSVALTNSGDLYSW 710
H ALTN G+L+ W
Sbjct: 404 SHFAALTNKGELFVW 418
Score = 46.0 bits (104), Expect = 1e-04
Identities = 44/166 (26%), Positives = 69/166 (41%), Gaps = 7/166 (4%)
Frame = +3
Query: 216 MFCWGNATHHELC--IDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYS 389
+F WGN+ + +L D +Q+ P + ++ A G L+ GH++
Sbjct: 304 LFGWGNSEYLQLASVTDSTQVN----VPRCLHFSGVGKVRQAACGGTGCAVLNGEGHVFV 359
Query: 390 CGNNDVGQLGRQTESDNGKN--PAL---VETFKDCTISTIACGLQHSLAIDEWGQPFSWG 554
G +G+ ES + P L E + +S I CGL H A+ G+ F WG
Sbjct: 360 WGYGILGKGPNLVESAVPEMIPPTLFGLTEFNPEIQVSRIRCGLSHFAALTNKGELFVWG 419
Query: 555 SDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNS 692
+ G LG +G +D+ + + VACG H V L S
Sbjct: 420 KNIRGCLG--IG-RLEDQYFPWRVTMPGEPVDVACGVDHMVTLAKS 462
>BC007823-1|AAH07823.1| 464|Homo sapiens Williams-Beuren syndrome
chromosome region 16 protein.
Length = 464
Score = 62.1 bits (144), Expect = 2e-09
Identities = 42/136 (30%), Positives = 64/136 (47%), Gaps = 3/136 (2%)
Frame = +3
Query: 312 ESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQ-TESDNGKNPALVETFKDC--T 482
+ + V+ G HSL L++ ++S GNN GQ GR+ E++ V +D
Sbjct: 172 QETRVLQVSCGRAHSLVLTDREGVFSMGNNSYGQCGRKVVENEIYSESHRVHRMQDFDGQ 231
Query: 483 ISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACG 662
+ +ACG HSL + + G+ +S G + GQ G K LA NVIQVA
Sbjct: 232 VVQVACGQDHSLFLTDKGEVYSCGWGADGQTGLGHYNITSSPTKLGGDLAGVNVIQVATY 291
Query: 663 AYHSVALTNSGDLYSW 710
+A++ G L+ W
Sbjct: 292 GDCCLAVSADGGLFGW 307
Score = 53.2 bits (122), Expect = 9e-07
Identities = 34/126 (26%), Positives = 51/126 (40%)
Frame = +3
Query: 333 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQH 512
VA G+ HSL+L++ G +YSCG GQ G + L + +A
Sbjct: 235 VACGQDHSLFLTDKGEVYSCGWGADGQTGLGHYNITSSPTKLGGDLAGVNVIQVATYGDC 294
Query: 513 SLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNS 692
LA+ G F WG+ QL + + + P+ + V Q ACG L
Sbjct: 295 CLAVSADGGLFGWGNSEYLQLASVTDSTQVNVPRCLHFSGVGKVRQAACGGTGCAVLNGE 354
Query: 693 GDLYSW 710
G ++ W
Sbjct: 355 GHVFVW 360
Score = 50.4 bits (115), Expect = 6e-06
Identities = 41/135 (30%), Positives = 59/135 (43%), Gaps = 6/135 (4%)
Frame = +3
Query: 324 IQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACG 503
IQ G+ L +S G L+ GN++ QL T+S P + + ACG
Sbjct: 286 IQVATYGDC-CLAVSADGGLFGWGNSEYLQLASVTDSTQVNVPRCLHFSGVGKVRQAACG 344
Query: 504 LQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDK--PKFVKGLATKN----VIQVACGA 665
++ G F WG +G+ G NL A + P + GL N V ++ CG
Sbjct: 345 GTGCAVLNGEGHVFVWGYGILGK-GPNLVESAVPEMIPPTLFGLTEFNPEIQVSRIRCGL 403
Query: 666 YHSVALTNSGDLYSW 710
H ALTN G+L+ W
Sbjct: 404 SHFAALTNKGELFVW 418
Score = 46.0 bits (104), Expect = 1e-04
Identities = 44/166 (26%), Positives = 69/166 (41%), Gaps = 7/166 (4%)
Frame = +3
Query: 216 MFCWGNATHHELC--IDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYS 389
+F WGN+ + +L D +Q+ P + ++ A G L+ GH++
Sbjct: 304 LFGWGNSEYLQLASVTDSTQVN----VPRCLHFSGVGKVRQAACGGTGCAVLNGEGHVFV 359
Query: 390 CGNNDVGQLGRQTESDNGKN--PAL---VETFKDCTISTIACGLQHSLAIDEWGQPFSWG 554
G +G+ ES + P L E + +S I CGL H A+ G+ F WG
Sbjct: 360 WGYGILGKGPNLVESAVPEMIPPTLFGLTEFNPEIQVSRIRCGLSHFAALTNKGELFVWG 419
Query: 555 SDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNS 692
+ G LG +G +D+ + + VACG H V L S
Sbjct: 420 KNIRGCLG--IG-RLEDQYFPWRVTMPGEPVDVACGVDHMVTLAKS 462
>AF410455-1|AAM62304.1| 464|Homo sapiens RCC1-like G exchanging
factor-like protein protein.
Length = 464
Score = 62.1 bits (144), Expect = 2e-09
Identities = 42/136 (30%), Positives = 64/136 (47%), Gaps = 3/136 (2%)
Frame = +3
Query: 312 ESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQ-TESDNGKNPALVETFKDC--T 482
+ + V+ G HSL L++ ++S GNN GQ GR+ E++ V +D
Sbjct: 172 QETRVLQVSCGRAHSLVLTDREGVFSMGNNSYGQCGRKVVENEIYSESHRVHRMQDFDGQ 231
Query: 483 ISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACG 662
+ +ACG HSL + + G+ +S G + GQ G K LA NVIQVA
Sbjct: 232 VVQVACGQDHSLFLTDKGEVYSCGWGADGQTGLGHYNITSSPTKLGGDLAGVNVIQVATY 291
Query: 663 AYHSVALTNSGDLYSW 710
+A++ G L+ W
Sbjct: 292 GDCCLAVSADGGLFGW 307
Score = 53.2 bits (122), Expect = 9e-07
Identities = 34/126 (26%), Positives = 51/126 (40%)
Frame = +3
Query: 333 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQH 512
VA G+ HSL+L++ G +YSCG GQ G + L + +A
Sbjct: 235 VACGQDHSLFLTDKGEVYSCGWGADGQTGLGHYNITSSPTKLGGDLAGVNVIQVATYGDC 294
Query: 513 SLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNS 692
LA+ G F WG+ QL + + + P+ + V Q ACG L
Sbjct: 295 CLAVSADGGLFGWGNSEYLQLASVTDSTQVNVPRCLHFSGVGKVRQAACGGTGCAVLNGE 354
Query: 693 GDLYSW 710
G ++ W
Sbjct: 355 GHVFVW 360
Score = 50.4 bits (115), Expect = 6e-06
Identities = 41/135 (30%), Positives = 59/135 (43%), Gaps = 6/135 (4%)
Frame = +3
Query: 324 IQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACG 503
IQ G+ L +S G L+ GN++ QL T+S P + + ACG
Sbjct: 286 IQVATYGDC-CLAVSADGGLFGWGNSEYLQLASVTDSTQVNVPRCLHFSGVGKVRQAACG 344
Query: 504 LQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDK--PKFVKGLATKN----VIQVACGA 665
++ G F WG +G+ G NL A + P + GL N V ++ CG
Sbjct: 345 GTGCAVLNGEGHVFVWGYGILGK-GPNLVESAVPEMIPPTLFGLTEFNPEIQVSRIRCGL 403
Query: 666 YHSVALTNSGDLYSW 710
H ALTN G+L+ W
Sbjct: 404 SHFAALTNKGELFVW 418
Score = 46.0 bits (104), Expect = 1e-04
Identities = 44/166 (26%), Positives = 69/166 (41%), Gaps = 7/166 (4%)
Frame = +3
Query: 216 MFCWGNATHHELC--IDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYS 389
+F WGN+ + +L D +Q+ P + ++ A G L+ GH++
Sbjct: 304 LFGWGNSEYLQLASVTDSTQVN----VPRCLHFSGVGKVRQAACGGTGCAVLNGEGHVFV 359
Query: 390 CGNNDVGQLGRQTESDNGKN--PAL---VETFKDCTISTIACGLQHSLAIDEWGQPFSWG 554
G +G+ ES + P L E + +S I CGL H A+ G+ F WG
Sbjct: 360 WGYGILGKGPNLVESAVPEMIPPTLFGLTEFNPEIQVSRIRCGLSHFAALTNKGELFVWG 419
Query: 555 SDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNS 692
+ G LG +G +D+ + + VACG H V L S
Sbjct: 420 KNIRGCLG--IG-RLEDQYFPWRVTMPGEPVDVACGVDHMVTLAKS 462
>DQ005634-1|AAY55907.1| 1196|Homo sapiens inhibitor of Bruton's
tyrosine kinase-beta protein.
Length = 1196
Score = 61.3 bits (142), Expect = 3e-09
Identities = 39/127 (30%), Positives = 65/127 (51%), Gaps = 5/127 (3%)
Frame = +3
Query: 321 HIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIAC 500
+I+ V +FHS++LS G +Y+CG+ G+LG E P LVE S +A
Sbjct: 178 YIKQVVLCKFHSVFLSQKGQVYTCGHGPGGRLGHGDE-QTCLVPRLVEGLNGHNCSQVAA 236
Query: 501 GLQHSLAIDEWGQPFSWGSDSMGQLG-----NNLGAHAQDKPKFVKGLATKNVIQVACGA 665
H++ + E G +++G + QLG ++ Q + K++KG + +I VA G
Sbjct: 237 AKDHTVVLTEDGCVYTFGLNIFHQLGIIPPPSSCNVPRQIQAKYLKG---RTIIGVAAGR 293
Query: 666 YHSVALT 686
+H+V T
Sbjct: 294 FHTVLWT 300
Score = 44.8 bits (101), Expect = 3e-04
Identities = 33/113 (29%), Positives = 55/113 (48%), Gaps = 3/113 (2%)
Frame = +3
Query: 381 LYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTI---STIACGLQHSLAIDEWGQPFSW 551
+Y+ G+N LG +++ +P LV+ F I + C HS+ + + GQ ++
Sbjct: 144 VYTWGDNTNFTLGHGSQNSK-HHPELVDLFSRSGIYIKQVVLCKF-HSVFLSQKGQVYTC 201
Query: 552 GSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
G G+LG+ P+ V+GL N QVA H+V LT G +Y++
Sbjct: 202 GHGPGGRLGHG-DEQTCLVPRLVEGLNGHNCSQVAAAKDHTVVLTEDGCVYTF 253
Score = 35.9 bits (79), Expect = 0.14
Identities = 41/153 (26%), Positives = 63/153 (41%), Gaps = 5/153 (3%)
Frame = +3
Query: 261 GSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDN 440
G + T LV P L + + VAA + H++ L+ G +Y+ G N QLG +
Sbjct: 212 GDEQTCLV--PRLVEGLNGHNCSQVAAAKDHTVVLTEDGCVYTFGLNIFHQLGIIPPPSS 269
Query: 441 GKNPALVET--FKDCTISTIACGLQHS-LAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKP 611
P ++ K TI +A G H+ L E +G L + G P
Sbjct: 270 CNVPRQIQAKYLKGRTIIGVAAGRFHTVLWTREAVYTMGLNGGQLGCLLDPNGEKCVTAP 329
Query: 612 KFVKGLATKNVI--QVACGAYHSVALTNSGDLY 704
+ V L K++ VA +V +T GD+Y
Sbjct: 330 RQVSALHHKDIALSLVAASDGATVCVTTRGDIY 362
>DQ005633-1|AAY55906.1| 1353|Homo sapiens inhibitor of Bruton's
tyrosine kinase-alpha protein.
Length = 1353
Score = 61.3 bits (142), Expect = 3e-09
Identities = 39/127 (30%), Positives = 65/127 (51%), Gaps = 5/127 (3%)
Frame = +3
Query: 321 HIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIAC 500
+I+ V +FHS++LS G +Y+CG+ G+LG E P LVE S +A
Sbjct: 178 YIKQVVLCKFHSVFLSQKGQVYTCGHGPGGRLGHGDE-QTCLVPRLVEGLNGHNCSQVAA 236
Query: 501 GLQHSLAIDEWGQPFSWGSDSMGQLG-----NNLGAHAQDKPKFVKGLATKNVIQVACGA 665
H++ + E G +++G + QLG ++ Q + K++KG + +I VA G
Sbjct: 237 AKDHTVVLTEDGCVYTFGLNIFHQLGIIPPPSSCNVPRQIQAKYLKG---RTIIGVAAGR 293
Query: 666 YHSVALT 686
+H+V T
Sbjct: 294 FHTVLWT 300
Score = 44.8 bits (101), Expect = 3e-04
Identities = 33/113 (29%), Positives = 55/113 (48%), Gaps = 3/113 (2%)
Frame = +3
Query: 381 LYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTI---STIACGLQHSLAIDEWGQPFSW 551
+Y+ G+N LG +++ +P LV+ F I + C HS+ + + GQ ++
Sbjct: 144 VYTWGDNTNFTLGHGSQNSK-HHPELVDLFSRSGIYIKQVVLCKF-HSVFLSQKGQVYTC 201
Query: 552 GSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
G G+LG+ P+ V+GL N QVA H+V LT G +Y++
Sbjct: 202 GHGPGGRLGHG-DEQTCLVPRLVEGLNGHNCSQVAAAKDHTVVLTEDGCVYTF 253
Score = 35.9 bits (79), Expect = 0.14
Identities = 41/153 (26%), Positives = 63/153 (41%), Gaps = 5/153 (3%)
Frame = +3
Query: 261 GSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDN 440
G + T LV P L + + VAA + H++ L+ G +Y+ G N QLG +
Sbjct: 212 GDEQTCLV--PRLVEGLNGHNCSQVAAAKDHTVVLTEDGCVYTFGLNIFHQLGIIPPPSS 269
Query: 441 GKNPALVET--FKDCTISTIACGLQHS-LAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKP 611
P ++ K TI +A G H+ L E +G L + G P
Sbjct: 270 CNVPRQIQAKYLKGRTIIGVAAGRFHTVLWTREAVYTMGLNGGQLGCLLDPNGEKCVTAP 329
Query: 612 KFVKGLATKNVI--QVACGAYHSVALTNSGDLY 704
+ V L K++ VA +V +T GD+Y
Sbjct: 330 RQVSALHHKDIALSLVAASDGATVCVTTRGDIY 362
>BC113698-1|AAI13699.1| 1353|Homo sapiens inhibitor of Bruton
agammaglobulinemia tyrosine kinase protein.
Length = 1353
Score = 61.3 bits (142), Expect = 3e-09
Identities = 39/127 (30%), Positives = 65/127 (51%), Gaps = 5/127 (3%)
Frame = +3
Query: 321 HIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIAC 500
+I+ V +FHS++LS G +Y+CG+ G+LG E P LVE S +A
Sbjct: 178 YIKQVVLCKFHSVFLSQKGQVYTCGHGPGGRLGHGDE-QTCLVPRLVEGLNGHNCSQVAA 236
Query: 501 GLQHSLAIDEWGQPFSWGSDSMGQLG-----NNLGAHAQDKPKFVKGLATKNVIQVACGA 665
H++ + E G +++G + QLG ++ Q + K++KG + +I VA G
Sbjct: 237 AKDHTVVLTEDGCVYTFGLNIFHQLGIIPPPSSCNVPRQIQAKYLKG---RTIIGVAAGR 293
Query: 666 YHSVALT 686
+H+V T
Sbjct: 294 FHTVLWT 300
Score = 44.8 bits (101), Expect = 3e-04
Identities = 33/113 (29%), Positives = 55/113 (48%), Gaps = 3/113 (2%)
Frame = +3
Query: 381 LYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTI---STIACGLQHSLAIDEWGQPFSW 551
+Y+ G+N LG +++ +P LV+ F I + C HS+ + + GQ ++
Sbjct: 144 VYTWGDNTNFTLGHGSQNSK-HHPELVDLFSRSGIYIKQVVLCKF-HSVFLSQKGQVYTC 201
Query: 552 GSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
G G+LG+ P+ V+GL N QVA H+V LT G +Y++
Sbjct: 202 GHGPGGRLGHG-DEQTCLVPRLVEGLNGHNCSQVAAAKDHTVVLTEDGCVYTF 253
Score = 35.9 bits (79), Expect = 0.14
Identities = 41/153 (26%), Positives = 63/153 (41%), Gaps = 5/153 (3%)
Frame = +3
Query: 261 GSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDN 440
G + T LV P L + + VAA + H++ L+ G +Y+ G N QLG +
Sbjct: 212 GDEQTCLV--PRLVEGLNGHNCSQVAAAKDHTVVLTEDGCVYTFGLNIFHQLGIIPPPSS 269
Query: 441 GKNPALVET--FKDCTISTIACGLQHS-LAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKP 611
P ++ K TI +A G H+ L E +G L + G P
Sbjct: 270 CNVPRQIQAKYLKGRTIIGVAAGRFHTVLWTREAVYTMGLNGGQLGCLLDPNGEKCVTAP 329
Query: 612 KFVKGLATKNVI--QVACGAYHSVALTNSGDLY 704
+ V L K++ VA +V +T GD+Y
Sbjct: 330 RQVSALHHKDIALSLVAASDGATVCVTTRGDIY 362
>BC113696-1|AAI13697.1| 1353|Homo sapiens inhibitor of Bruton
agammaglobulinemia tyrosine kinase protein.
Length = 1353
Score = 61.3 bits (142), Expect = 3e-09
Identities = 39/127 (30%), Positives = 65/127 (51%), Gaps = 5/127 (3%)
Frame = +3
Query: 321 HIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIAC 500
+I+ V +FHS++LS G +Y+CG+ G+LG E P LVE S +A
Sbjct: 178 YIKQVVLCKFHSVFLSQKGQVYTCGHGPGGRLGHGDE-QTCLVPRLVEGLNGHNCSQVAA 236
Query: 501 GLQHSLAIDEWGQPFSWGSDSMGQLG-----NNLGAHAQDKPKFVKGLATKNVIQVACGA 665
H++ + E G +++G + QLG ++ Q + K++KG + +I VA G
Sbjct: 237 AKDHTVVLTEDGCVYTFGLNIFHQLGIIPPPSSCNVPRQIQAKYLKG---RTIIGVAAGR 293
Query: 666 YHSVALT 686
+H+V T
Sbjct: 294 FHTVLWT 300
Score = 44.8 bits (101), Expect = 3e-04
Identities = 33/113 (29%), Positives = 55/113 (48%), Gaps = 3/113 (2%)
Frame = +3
Query: 381 LYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTI---STIACGLQHSLAIDEWGQPFSW 551
+Y+ G+N LG +++ +P LV+ F I + C HS+ + + GQ ++
Sbjct: 144 VYTWGDNTNFTLGHGSQNSK-HHPELVDLFSRSGIYIKQVVLCKF-HSVFLSQKGQVYTC 201
Query: 552 GSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
G G+LG+ P+ V+GL N QVA H+V LT G +Y++
Sbjct: 202 GHGPGGRLGHG-DEQTCLVPRLVEGLNGHNCSQVAAAKDHTVVLTEDGCVYTF 253
Score = 35.9 bits (79), Expect = 0.14
Identities = 41/153 (26%), Positives = 63/153 (41%), Gaps = 5/153 (3%)
Frame = +3
Query: 261 GSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDN 440
G + T LV P L + + VAA + H++ L+ G +Y+ G N QLG +
Sbjct: 212 GDEQTCLV--PRLVEGLNGHNCSQVAAAKDHTVVLTEDGCVYTFGLNIFHQLGIIPPPSS 269
Query: 441 GKNPALVET--FKDCTISTIACGLQHS-LAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKP 611
P ++ K TI +A G H+ L E +G L + G P
Sbjct: 270 CNVPRQIQAKYLKGRTIIGVAAGRFHTVLWTREAVYTMGLNGGQLGCLLDPNGEKCVTAP 329
Query: 612 KFVKGLATKNVI--QVACGAYHSVALTNSGDLY 704
+ V L K++ VA +V +T GD+Y
Sbjct: 330 RQVSALHHKDIALSLVAASDGATVCVTTRGDIY 362
>AL050333-2|CAI23416.1| 1187|Homo sapiens RP1-93K22.1 protein.
Length = 1187
Score = 61.3 bits (142), Expect = 3e-09
Identities = 39/127 (30%), Positives = 65/127 (51%), Gaps = 5/127 (3%)
Frame = +3
Query: 321 HIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIAC 500
+I+ V +FHS++LS G +Y+CG+ G+LG E P LVE S +A
Sbjct: 174 YIKQVVLCKFHSVFLSQKGQVYTCGHGPGGRLGHGDE-QTCLVPRLVEGLNGHNCSQVAA 232
Query: 501 GLQHSLAIDEWGQPFSWGSDSMGQLG-----NNLGAHAQDKPKFVKGLATKNVIQVACGA 665
H++ + E G +++G + QLG ++ Q + K++KG + +I VA G
Sbjct: 233 AKDHTVVLTEDGCVYTFGLNIFHQLGIIPPPSSCNVPRQIQAKYLKG---RTIIGVAAGR 289
Query: 666 YHSVALT 686
+H+V T
Sbjct: 290 FHTVLWT 296
Score = 44.8 bits (101), Expect = 3e-04
Identities = 33/113 (29%), Positives = 55/113 (48%), Gaps = 3/113 (2%)
Frame = +3
Query: 381 LYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTI---STIACGLQHSLAIDEWGQPFSW 551
+Y+ G+N LG +++ +P LV+ F I + C HS+ + + GQ ++
Sbjct: 140 VYTWGDNTNFTLGHGSQNSK-HHPELVDLFSRSGIYIKQVVLCKF-HSVFLSQKGQVYTC 197
Query: 552 GSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
G G+LG+ P+ V+GL N QVA H+V LT G +Y++
Sbjct: 198 GHGPGGRLGHG-DEQTCLVPRLVEGLNGHNCSQVAAAKDHTVVLTEDGCVYTF 249
Score = 35.9 bits (79), Expect = 0.14
Identities = 41/153 (26%), Positives = 63/153 (41%), Gaps = 5/153 (3%)
Frame = +3
Query: 261 GSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDN 440
G + T LV P L + + VAA + H++ L+ G +Y+ G N QLG +
Sbjct: 208 GDEQTCLV--PRLVEGLNGHNCSQVAAAKDHTVVLTEDGCVYTFGLNIFHQLGIIPPPSS 265
Query: 441 GKNPALVET--FKDCTISTIACGLQHS-LAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKP 611
P ++ K TI +A G H+ L E +G L + G P
Sbjct: 266 CNVPRQIQAKYLKGRTIIGVAAGRFHTVLWTREAVYTMGLNGGQLGCLLDPNGEKCVTAP 325
Query: 612 KFVKGLATKNVI--QVACGAYHSVALTNSGDLY 704
+ V L K++ VA +V +T GD+Y
Sbjct: 326 RQVSALHHKDIALSLVAASDGATVCVTTRGDIY 358
>AB037838-1|BAA92655.2| 1379|Homo sapiens KIAA1417 protein protein.
Length = 1379
Score = 61.3 bits (142), Expect = 3e-09
Identities = 39/127 (30%), Positives = 65/127 (51%), Gaps = 5/127 (3%)
Frame = +3
Query: 321 HIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIAC 500
+I+ V +FHS++LS G +Y+CG+ G+LG E P LVE S +A
Sbjct: 204 YIKQVVLCKFHSVFLSQKGQVYTCGHGPGGRLGHGDE-QTCLVPRLVEGLNGHNCSQVAA 262
Query: 501 GLQHSLAIDEWGQPFSWGSDSMGQLG-----NNLGAHAQDKPKFVKGLATKNVIQVACGA 665
H++ + E G +++G + QLG ++ Q + K++KG + +I VA G
Sbjct: 263 AKDHTVVLTEDGCVYTFGLNIFHQLGIIPPPSSCNVPRQIQAKYLKG---RTIIGVAAGR 319
Query: 666 YHSVALT 686
+H+V T
Sbjct: 320 FHTVLWT 326
Score = 44.8 bits (101), Expect = 3e-04
Identities = 33/113 (29%), Positives = 55/113 (48%), Gaps = 3/113 (2%)
Frame = +3
Query: 381 LYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTI---STIACGLQHSLAIDEWGQPFSW 551
+Y+ G+N LG +++ +P LV+ F I + C HS+ + + GQ ++
Sbjct: 170 VYTWGDNTNFTLGHGSQNSK-HHPELVDLFSRSGIYIKQVVLCKF-HSVFLSQKGQVYTC 227
Query: 552 GSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
G G+LG+ P+ V+GL N QVA H+V LT G +Y++
Sbjct: 228 GHGPGGRLGHG-DEQTCLVPRLVEGLNGHNCSQVAAAKDHTVVLTEDGCVYTF 279
Score = 35.9 bits (79), Expect = 0.14
Identities = 41/153 (26%), Positives = 63/153 (41%), Gaps = 5/153 (3%)
Frame = +3
Query: 261 GSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDN 440
G + T LV P L + + VAA + H++ L+ G +Y+ G N QLG +
Sbjct: 238 GDEQTCLV--PRLVEGLNGHNCSQVAAAKDHTVVLTEDGCVYTFGLNIFHQLGIIPPPSS 295
Query: 441 GKNPALVET--FKDCTISTIACGLQHS-LAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKP 611
P ++ K TI +A G H+ L E +G L + G P
Sbjct: 296 CNVPRQIQAKYLKGRTIIGVAAGRFHTVLWTREAVYTMGLNGGQLGCLLDPNGEKCVTAP 355
Query: 612 KFVKGLATKNVI--QVACGAYHSVALTNSGDLY 704
+ V L K++ VA +V +T GD+Y
Sbjct: 356 RQVSALHHKDIALSLVAASDGATVCVTTRGDIY 388
>AY650032-1|AAV66578.1| 117|Homo sapiens HECT and RCC1 containing
protein 4 isoform 2 protein.
Length = 117
Score = 56.8 bits (131), Expect = 7e-08
Identities = 31/93 (33%), Positives = 53/93 (56%)
Frame = +3
Query: 216 MFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCG 395
M CWGNA+ +L + G ++V++P S + + ++ V G H++++ + G +Y+CG
Sbjct: 1 MLCWGNASFGQLGLGGID-EEIVLEPRKSDFFINKRVRDVGCGLRHTVFVLDDGTVYTCG 59
Query: 396 NNDVGQLGRQTESDNGKNPALVETFKDCTISTI 494
ND+GQLG + + K P E K C IS +
Sbjct: 60 CNDLGQLGHE---KSRKKP---EILKVCQISRL 86
Score = 36.3 bits (80), Expect = 0.11
Identities = 21/78 (26%), Positives = 41/78 (52%), Gaps = 1/78 (1%)
Frame = +3
Query: 393 GNNDVGQLGRQ-TESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMG 569
GN GQLG + + P + F + + + CGL+H++ + + G ++ G + +G
Sbjct: 5 GNASFGQLGLGGIDEEIVLEPRKSDFFINKRVRDVGCGLRHTVFVLDDGTVYTCGCNDLG 64
Query: 570 QLGNNLGAHAQDKPKFVK 623
QLG+ ++ KP+ +K
Sbjct: 65 QLGHE---KSRKKPEILK 79
Score = 32.7 bits (71), Expect = 1.3
Identities = 17/54 (31%), Positives = 26/54 (48%), Gaps = 1/54 (1%)
Frame = +3
Query: 549 WGSDSMGQLG-NNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYS 707
WG+ S GQLG + +P+ K V V CG H+V + + G +Y+
Sbjct: 4 WGNASFGQLGLGGIDEEIVLEPRKSDFFINKRVRDVGCGLRHTVFVLDDGTVYT 57
>AY650034-1|AAV66580.1| 110|Homo sapiens HECT and RCC1 containing
protein 4 isoform 4 protein.
Length = 110
Score = 55.6 bits (128), Expect = 2e-07
Identities = 24/70 (34%), Positives = 44/70 (62%)
Frame = +3
Query: 216 MFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCG 395
M CWGNA+ +L + G ++V++P S + + ++ V G H++++ + G +Y+CG
Sbjct: 1 MLCWGNASFGQLGLGGID-EEIVLEPRKSDFFINKRVRDVGCGLRHTVFVLDDGTVYTCG 59
Query: 396 NNDVGQLGRQ 425
ND+GQLG +
Sbjct: 60 CNDLGQLGHE 69
Score = 36.3 bits (80), Expect = 0.11
Identities = 21/76 (27%), Positives = 40/76 (52%), Gaps = 1/76 (1%)
Frame = +3
Query: 393 GNNDVGQLGRQ-TESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMG 569
GN GQLG + + P + F + + + CGL+H++ + + G ++ G + +G
Sbjct: 5 GNASFGQLGLGGIDEEIVLEPRKSDFFINKRVRDVGCGLRHTVFVLDDGTVYTCGCNDLG 64
Query: 570 QLGNNLGAHAQDKPKF 617
QLG+ ++ KP+F
Sbjct: 65 QLGHE---KSRKKPEF 77
Score = 32.7 bits (71), Expect = 1.3
Identities = 17/54 (31%), Positives = 26/54 (48%), Gaps = 1/54 (1%)
Frame = +3
Query: 549 WGSDSMGQLG-NNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYS 707
WG+ S GQLG + +P+ K V V CG H+V + + G +Y+
Sbjct: 4 WGNASFGQLGLGGIDEEIVLEPRKSDFFINKRVRDVGCGLRHTVFVLDDGTVYT 57
>BC113705-1|AAI13706.1| 692|Homo sapiens NIMA (never in mitosis
gene a)- related kinase 8 protein.
Length = 692
Score = 54.8 bits (126), Expect = 3e-07
Identities = 38/125 (30%), Positives = 61/125 (48%), Gaps = 1/125 (0%)
Frame = +3
Query: 324 IQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACG 503
I+ VA G+F + L++ G + + G+ G LG + +D + P +VE + +ACG
Sbjct: 393 IKHVACGDFFTACLTDRGIIMTFGSGSNGCLGHGSLTDISQ-PTIVEALLGYEMVQVACG 451
Query: 504 LQHSLAIDEWGQPFSWGSDSMGQLGNNLGA-HAQDKPKFVKGLATKNVIQVACGAYHSVA 680
H LA+ + F+WG G+LG LG + P+ V + +V CG S+
Sbjct: 452 ASHVLALSTERELFAWGRGDSGRLG--LGTRESHSCPQQVPMPPGQEAQRVVCGIDSSMI 509
Query: 681 LTNSG 695
LT G
Sbjct: 510 LTVPG 514
Score = 52.8 bits (121), Expect = 1e-06
Identities = 26/89 (29%), Positives = 48/89 (53%)
Frame = +3
Query: 312 ESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTIST 491
+ + + ++ G HS ++ SG Y+ G+N GQLG T + + P V+ + ++
Sbjct: 559 DQEPLLSIDLGTAHSAAVTASGDCYTFGSNQHGQLGTNTRRGS-RAPCKVQGLEGIKMAM 617
Query: 492 IACGLQHSLAIDEWGQPFSWGSDSMGQLG 578
+ACG ++AI + +SWG + G+LG
Sbjct: 618 VACGDAFTVAIGAESEVYSWGKGARGRLG 646
Score = 50.8 bits (116), Expect = 5e-06
Identities = 47/185 (25%), Positives = 76/185 (41%), Gaps = 14/185 (7%)
Frame = +3
Query: 198 LQNYKKMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSG 377
L +++F WG L + + + + +E+ Q V G S+ L+ G
Sbjct: 458 LSTERELFAWGRGDSGRLGLGTRESHSCPQQVPMPPGQEA---QRVVCGIDSSMILTVPG 514
Query: 378 HLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTIST--------------IACGLQHS 515
+CG+N +LG S G+ P + ++ T I G HS
Sbjct: 515 QALACGSNRFNKLGLDHLS-LGEEPVPHQQVEEALSFTLLGSAPLDQEPLLSIDLGTAHS 573
Query: 516 LAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSG 695
A+ G +++GS+ GQLG N P V+GL + VACG +VA+
Sbjct: 574 AAVTASGDCYTFGSNQHGQLGTNT-RRGSRAPCKVQGLEGIKMAMVACGDAFTVAIGAES 632
Query: 696 DLYSW 710
++YSW
Sbjct: 633 EVYSW 637
Score = 48.0 bits (109), Expect = 3e-05
Identities = 26/77 (33%), Positives = 42/77 (54%)
Frame = +3
Query: 480 TISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVAC 659
TI +ACG + + + G ++GS S G LG+ +P V+ L ++QVAC
Sbjct: 392 TIKHVACGDFFTACLTDRGIIMTFGSGSNGCLGHGSLTDIS-QPTIVEALLGYEMVQVAC 450
Query: 660 GAYHSVALTNSGDLYSW 710
GA H +AL+ +L++W
Sbjct: 451 GASHVLALSTERELFAW 467
Score = 31.5 bits (68), Expect = 3.1
Identities = 14/56 (25%), Positives = 28/56 (50%)
Frame = +3
Query: 333 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIAC 500
VA G+ ++ + +YS G G+LGR+ E P ++ T+++++C
Sbjct: 618 VACGDAFTVAIGAESEVYSWGKGARGRLGRRDEDAGLPRPVQLDETHPYTVTSVSC 673
>BC112240-1|AAI12241.1| 692|Homo sapiens NIMA-related kinase 8
protein.
Length = 692
Score = 54.8 bits (126), Expect = 3e-07
Identities = 38/125 (30%), Positives = 61/125 (48%), Gaps = 1/125 (0%)
Frame = +3
Query: 324 IQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACG 503
I+ VA G+F + L++ G + + G+ G LG + +D + P +VE + +ACG
Sbjct: 393 IKHVACGDFFTACLTDRGIIMTFGSGSNGCLGHGSLTDISQ-PTIVEALLGYEMVQVACG 451
Query: 504 LQHSLAIDEWGQPFSWGSDSMGQLGNNLGA-HAQDKPKFVKGLATKNVIQVACGAYHSVA 680
H LA+ + F+WG G+LG LG + P+ V + +V CG S+
Sbjct: 452 ASHVLALSTERELFAWGRGDSGRLG--LGTRESHSCPQQVPMPPGQEAQRVVCGIDSSMI 509
Query: 681 LTNSG 695
LT G
Sbjct: 510 LTVPG 514
Score = 52.8 bits (121), Expect = 1e-06
Identities = 26/89 (29%), Positives = 48/89 (53%)
Frame = +3
Query: 312 ESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTIST 491
+ + + ++ G HS ++ SG Y+ G+N GQLG T + + P V+ + ++
Sbjct: 559 DQEPLLSIDLGTAHSAAVTASGDCYTFGSNQHGQLGTNTRRGS-RAPCKVQGLEGIKMAM 617
Query: 492 IACGLQHSLAIDEWGQPFSWGSDSMGQLG 578
+ACG ++AI + +SWG + G+LG
Sbjct: 618 VACGDAFTVAIGAESEVYSWGKGARGRLG 646
Score = 50.8 bits (116), Expect = 5e-06
Identities = 47/185 (25%), Positives = 76/185 (41%), Gaps = 14/185 (7%)
Frame = +3
Query: 198 LQNYKKMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSG 377
L +++F WG L + + + + +E+ Q V G S+ L+ G
Sbjct: 458 LSTERELFAWGRGDSGRLGLGTRESHSCPQQVPMPPGQEA---QRVVCGIDSSMILTVPG 514
Query: 378 HLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTIST--------------IACGLQHS 515
+CG+N +LG S G+ P + ++ T I G HS
Sbjct: 515 QALACGSNRFNKLGLDHLS-LGEEPVPHQQVEEALSFTLLGSAPLDQEPLLSIDLGTAHS 573
Query: 516 LAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSG 695
A+ G +++GS+ GQLG N P V+GL + VACG +VA+
Sbjct: 574 AAVTASGDCYTFGSNQHGQLGTNT-RRGSRAPCKVQGLEGIKMAMVACGDAFTVAIGAES 632
Query: 696 DLYSW 710
++YSW
Sbjct: 633 EVYSW 637
Score = 48.0 bits (109), Expect = 3e-05
Identities = 26/77 (33%), Positives = 42/77 (54%)
Frame = +3
Query: 480 TISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVAC 659
TI +ACG + + + G ++GS S G LG+ +P V+ L ++QVAC
Sbjct: 392 TIKHVACGDFFTACLTDRGIIMTFGSGSNGCLGHGSLTDIS-QPTIVEALLGYEMVQVAC 450
Query: 660 GAYHSVALTNSGDLYSW 710
GA H +AL+ +L++W
Sbjct: 451 GASHVLALSTERELFAW 467
Score = 31.5 bits (68), Expect = 3.1
Identities = 14/56 (25%), Positives = 28/56 (50%)
Frame = +3
Query: 333 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIAC 500
VA G+ ++ + +YS G G+LGR+ E P ++ T+++++C
Sbjct: 618 VACGDAFTVAIGAESEVYSWGKGARGRLGRRDEDAGLPRPVQLDETHPYTVTSVSC 673
>AY267371-1|AAP04006.1| 692|Homo sapiens NIMA-family kinase NEK8
protein.
Length = 692
Score = 54.8 bits (126), Expect = 3e-07
Identities = 38/125 (30%), Positives = 61/125 (48%), Gaps = 1/125 (0%)
Frame = +3
Query: 324 IQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACG 503
I+ VA G+F + L++ G + + G+ G LG + +D + P +VE + +ACG
Sbjct: 393 IKHVACGDFFTACLTDRGIIMTFGSGSNGCLGHGSLTDISQ-PTIVEALLGYEMVQVACG 451
Query: 504 LQHSLAIDEWGQPFSWGSDSMGQLGNNLGA-HAQDKPKFVKGLATKNVIQVACGAYHSVA 680
H LA+ + F+WG G+LG LG + P+ V + +V CG S+
Sbjct: 452 ASHVLALSTERELFAWGRGDSGRLG--LGTRESHSCPQQVPMPPGQEAQRVVCGIDSSMI 509
Query: 681 LTNSG 695
LT G
Sbjct: 510 LTVPG 514
Score = 52.8 bits (121), Expect = 1e-06
Identities = 26/89 (29%), Positives = 48/89 (53%)
Frame = +3
Query: 312 ESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTIST 491
+ + + ++ G HS ++ SG Y+ G+N GQLG T + + P V+ + ++
Sbjct: 559 DQEPLLSIDLGTAHSAAVTASGDCYTFGSNQHGQLGTNTRRGS-RAPCKVQGLEGIKMAM 617
Query: 492 IACGLQHSLAIDEWGQPFSWGSDSMGQLG 578
+ACG ++AI + +SWG + G+LG
Sbjct: 618 VACGDAFTVAIGAESEVYSWGKGARGRLG 646
Score = 50.8 bits (116), Expect = 5e-06
Identities = 47/185 (25%), Positives = 76/185 (41%), Gaps = 14/185 (7%)
Frame = +3
Query: 198 LQNYKKMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSG 377
L +++F WG L + + + + +E+ Q V G S+ L+ G
Sbjct: 458 LSTERELFAWGRGDSGRLGLGTRESHSCPQQVPMPPGQEA---QRVVCGIDSSMILTVPG 514
Query: 378 HLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTIST--------------IACGLQHS 515
+CG+N +LG S G+ P + ++ T I G HS
Sbjct: 515 QALACGSNRFNKLGLDHLS-LGEEPVPHQQVEEALSFTLLGSAPLDQEPLLSIDLGTAHS 573
Query: 516 LAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSG 695
A+ G +++GS+ GQLG N P V+GL + VACG +VA+
Sbjct: 574 AAVTASGDCYTFGSNQHGQLGTNT-RRGSRAPCKVQGLEGIKMAMVACGDAFTVAIGAES 632
Query: 696 DLYSW 710
++YSW
Sbjct: 633 EVYSW 637
Score = 48.0 bits (109), Expect = 3e-05
Identities = 26/77 (33%), Positives = 42/77 (54%)
Frame = +3
Query: 480 TISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVAC 659
TI +ACG + + + G ++GS S G LG+ +P V+ L ++QVAC
Sbjct: 392 TIKHVACGDFFTACLTDRGIIMTFGSGSNGCLGHGSLTDIS-QPTIVEALLGYEMVQVAC 450
Query: 660 GAYHSVALTNSGDLYSW 710
GA H +AL+ +L++W
Sbjct: 451 GASHVLALSTERELFAW 467
Score = 31.5 bits (68), Expect = 3.1
Identities = 14/56 (25%), Positives = 28/56 (50%)
Frame = +3
Query: 333 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIAC 500
VA G+ ++ + +YS G G+LGR+ E P ++ T+++++C
Sbjct: 618 VACGDAFTVAIGAESEVYSWGKGARGRLGRRDEDAGLPRPVQLDETHPYTVTSVSC 673
>AY242354-1|AAO88243.1| 692|Homo sapiens NIMA-related kinase 12a
protein.
Length = 692
Score = 54.8 bits (126), Expect = 3e-07
Identities = 38/125 (30%), Positives = 61/125 (48%), Gaps = 1/125 (0%)
Frame = +3
Query: 324 IQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACG 503
I+ VA G+F + L++ G + + G+ G LG + +D + P +VE + +ACG
Sbjct: 393 IKHVACGDFFTACLTDRGIIMTFGSGSNGCLGHGSLTDISQ-PTIVEALLGYEMVQVACG 451
Query: 504 LQHSLAIDEWGQPFSWGSDSMGQLGNNLGA-HAQDKPKFVKGLATKNVIQVACGAYHSVA 680
H LA+ + F+WG G+LG LG + P+ V + +V CG S+
Sbjct: 452 ASHVLALSTERELFAWGRGDSGRLG--LGTRESHSCPQQVPMPPGQEAQRVVCGIDSSMI 509
Query: 681 LTNSG 695
LT G
Sbjct: 510 LTVPG 514
Score = 52.8 bits (121), Expect = 1e-06
Identities = 26/89 (29%), Positives = 48/89 (53%)
Frame = +3
Query: 312 ESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTIST 491
+ + + ++ G HS ++ SG Y+ G+N GQLG T + + P V+ + ++
Sbjct: 559 DQEPLLSIDLGTAHSAAVTASGDCYTFGSNQHGQLGTNTRRGS-RAPCKVQGLEGIKMAM 617
Query: 492 IACGLQHSLAIDEWGQPFSWGSDSMGQLG 578
+ACG ++AI + +SWG + G+LG
Sbjct: 618 VACGDAFTVAIGAESEVYSWGKGARGRLG 646
Score = 50.8 bits (116), Expect = 5e-06
Identities = 47/185 (25%), Positives = 76/185 (41%), Gaps = 14/185 (7%)
Frame = +3
Query: 198 LQNYKKMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSG 377
L +++F WG L + + + + +E+ Q V G S+ L+ G
Sbjct: 458 LSTERELFAWGRGDSGRLGLGTRESHSCPQQVPMPPGQEA---QRVVCGIDSSMILTVPG 514
Query: 378 HLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTIST--------------IACGLQHS 515
+CG+N +LG S G+ P + ++ T I G HS
Sbjct: 515 QALACGSNRFNKLGLDHLS-LGEEPVPHQQVEEALSFTLLGSAPLDQEPLLSIDLGTAHS 573
Query: 516 LAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSG 695
A+ G +++GS+ GQLG N P V+GL + VACG +VA+
Sbjct: 574 AAVTASGDCYTFGSNQHGQLGTNT-RRGSRAPCKVQGLEGIKMAMVACGDAFTVAIGAES 632
Query: 696 DLYSW 710
++YSW
Sbjct: 633 EVYSW 637
Score = 48.0 bits (109), Expect = 3e-05
Identities = 26/77 (33%), Positives = 42/77 (54%)
Frame = +3
Query: 480 TISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVAC 659
TI +ACG + + + G ++GS S G LG+ +P V+ L ++QVAC
Sbjct: 392 TIKHVACGDFFTACLTDRGIIMTFGSGSNGCLGHGSLTDIS-QPTIVEALLGYEMVQVAC 450
Query: 660 GAYHSVALTNSGDLYSW 710
GA H +AL+ +L++W
Sbjct: 451 GASHVLALSTERELFAW 467
Score = 31.5 bits (68), Expect = 3.1
Identities = 14/56 (25%), Positives = 28/56 (50%)
Frame = +3
Query: 333 VAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIAC 500
VA G+ ++ + +YS G G+LGR+ E P ++ T+++++C
Sbjct: 618 VACGDAFTVAIGAESEVYSWGKGARGRLGRRDEDAGLPRPVQLDETHPYTVTSVSC 673
>BC112101-1|AAI12102.1| 979|Homo sapiens NIMA related kinase 9
protein.
Length = 979
Score = 53.6 bits (123), Expect = 7e-07
Identities = 37/132 (28%), Positives = 63/132 (47%), Gaps = 6/132 (4%)
Frame = +3
Query: 333 VAAGEFHSLYLSNSGHLYSC-----GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIA 497
V AG H ++ LY+ G GQLG ++ + P VE + I ++
Sbjct: 374 VCAGNTHFAVVTVEKELYTWVNMQGGTKLHGQLGHGDKASY-RQPKHVEKLQGKAIRQVS 432
Query: 498 CGLQHSLAIDEWGQPFSWGSDSMGQLG-NNLGAHAQDKPKFVKGLATKNVIQVACGAYHS 674
CG ++ + + GQ +++GSD G +G + + +P + + V QV+CG H
Sbjct: 433 CGDDFTVCVTDEGQLYAFGSDYYGCMGVDKVAGPEVLEPMQLNFFLSNPVEQVSCGDNHV 492
Query: 675 VALTNSGDLYSW 710
V LT + ++YSW
Sbjct: 493 VVLTRNKEVYSW 504
Score = 52.8 bits (121), Expect = 1e-06
Identities = 52/185 (28%), Positives = 85/185 (45%), Gaps = 14/185 (7%)
Frame = +3
Query: 198 LQNYKKMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSG 377
L K+++ WG + L +D + K + K + I AV G + L+ SG
Sbjct: 495 LTRNKEVYSWGCGEYGRLGLDSEEDYYTPQKVDVPK---ALIIVAVQCGCDGTFLLTQSG 551
Query: 378 HLYSCGNNDVGQLG-RQTESDNGKNPA-----------LVETFKDCTISTIACGLQHSLA 521
+ +CG N+ +LG Q S + A L + I TIA G H+ A
Sbjct: 552 KVLACGLNEFNKLGLNQCMSGIINHEAYHEVPYTTSFTLAKQLSFYKIRTIAPGKTHTAA 611
Query: 522 IDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKG--LATKNVIQVACGAYHSVALTNSG 695
IDE G+ ++G + GQLG +G + + + G L K VI+V+CG ++A T+
Sbjct: 612 IDERGRLLTFGCNKCGQLG--VGNYKKRLGINLLGGPLGGKQVIRVSCGDEFTIAATDDN 669
Query: 696 DLYSW 710
+++W
Sbjct: 670 HIFAW 674
Score = 44.0 bits (99), Expect = 5e-04
Identities = 29/125 (23%), Positives = 56/125 (44%), Gaps = 1/125 (0%)
Frame = +3
Query: 324 IQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLG-RQTESDNGKNPALVETFKDCTISTIAC 500
I+ V+ G+ ++ +++ G LY+ G++ G +G + P + F + ++C
Sbjct: 428 IRQVSCGDDFTVCVTDEGQLYAFGSDYYGCMGVDKVAGPEVLEPMQLNFFLSNPVEQVSC 487
Query: 501 GLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA 680
G H + + + +SWG G+LG + P+ V ++ V CG +
Sbjct: 488 GDNHVVVLTRNKEVYSWGCGEYGRLGLD-SEEDYYTPQKVDVPKALIIVAVQCGCDGTFL 546
Query: 681 LTNSG 695
LT SG
Sbjct: 547 LTQSG 551
Score = 39.5 bits (88), Expect = 0.012
Identities = 28/118 (23%), Positives = 48/118 (40%)
Frame = +3
Query: 222 CWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNN 401
C +HE + T + LS +K I+ +A G+ H+ + G L + G N
Sbjct: 569 CMSGIINHEAYHEVPYTTSFTLAKQLSFYK----IRTIAPGKTHTAAIDERGRLLTFGCN 624
Query: 402 DVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQL 575
GQLG L + ++CG + ++A + F+WG+ G+L
Sbjct: 625 KCGQLGVGNYKKRLGINLLGGPLGGKQVIRVSCGDEFTIAATDDNHIFAWGNGGNGRL 682
Score = 39.1 bits (87), Expect = 0.015
Identities = 28/97 (28%), Positives = 49/97 (50%), Gaps = 7/97 (7%)
Frame = +3
Query: 441 GKN-PALVETFKD-CTISTIACGLQHSLAIDEWGQPFSW-----GSDSMGQLGNNLGAHA 599
GK+ P ++ K C+ + G H + + ++W G+ GQLG+ A
Sbjct: 355 GKSTPQKLDVIKSGCSARQVCAGNTHFAVVTVEKELYTWVNMQGGTKLHGQLGHGDKASY 414
Query: 600 QDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
+ +PK V+ L K + QV+CG +V +T+ G LY++
Sbjct: 415 R-QPKHVEKLQGKAIRQVSCGDDFTVCVTDEGQLYAF 450
>BC093881-1|AAH93881.1| 979|Homo sapiens NIMA (never in mitosis
gene a)- related kinase 9 protein.
Length = 979
Score = 53.6 bits (123), Expect = 7e-07
Identities = 37/132 (28%), Positives = 63/132 (47%), Gaps = 6/132 (4%)
Frame = +3
Query: 333 VAAGEFHSLYLSNSGHLYSC-----GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIA 497
V AG H ++ LY+ G GQLG ++ + P VE + I ++
Sbjct: 374 VCAGNTHFAVVTVEKELYTWVNMQGGTKLHGQLGHGDKASY-RQPKHVEKLQGKAIRQVS 432
Query: 498 CGLQHSLAIDEWGQPFSWGSDSMGQLG-NNLGAHAQDKPKFVKGLATKNVIQVACGAYHS 674
CG ++ + + GQ +++GSD G +G + + +P + + V QV+CG H
Sbjct: 433 CGDDFTVCVTDEGQLYAFGSDYYGCMGVDKVAGPEVLEPMQLNFFLSNPVEQVSCGDNHV 492
Query: 675 VALTNSGDLYSW 710
V LT + ++YSW
Sbjct: 493 VVLTRNKEVYSW 504
Score = 52.8 bits (121), Expect = 1e-06
Identities = 52/185 (28%), Positives = 85/185 (45%), Gaps = 14/185 (7%)
Frame = +3
Query: 198 LQNYKKMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSG 377
L K+++ WG + L +D + K + K + I AV G + L+ SG
Sbjct: 495 LTRNKEVYSWGCGEYGRLGLDSEEDYYTPQKVDVPK---ALIIVAVQCGCDGTFLLTQSG 551
Query: 378 HLYSCGNNDVGQLG-RQTESDNGKNPA-----------LVETFKDCTISTIACGLQHSLA 521
+ +CG N+ +LG Q S + A L + I TIA G H+ A
Sbjct: 552 KVLACGLNEFNKLGLNQCMSGIINHEAYHEVPYTTSFTLAKQLSFYKIRTIAPGKTHTAA 611
Query: 522 IDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKG--LATKNVIQVACGAYHSVALTNSG 695
IDE G+ ++G + GQLG +G + + + G L K VI+V+CG ++A T+
Sbjct: 612 IDERGRLLTFGCNKCGQLG--VGNYKKRLGINLLGGPLGGKQVIRVSCGDEFTIAATDDN 669
Query: 696 DLYSW 710
+++W
Sbjct: 670 HIFAW 674
Score = 44.0 bits (99), Expect = 5e-04
Identities = 29/125 (23%), Positives = 56/125 (44%), Gaps = 1/125 (0%)
Frame = +3
Query: 324 IQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLG-RQTESDNGKNPALVETFKDCTISTIAC 500
I+ V+ G+ ++ +++ G LY+ G++ G +G + P + F + ++C
Sbjct: 428 IRQVSCGDDFTVCVTDEGQLYAFGSDYYGCMGVDKVAGPEVLEPMQLNFFLSNPVEQVSC 487
Query: 501 GLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA 680
G H + + + +SWG G+LG + P+ V ++ V CG +
Sbjct: 488 GDNHVVVLTRNKEVYSWGCGEYGRLGLD-SEEDYYTPQKVDVPKALIIVAVQCGCDGTFL 546
Query: 681 LTNSG 695
LT SG
Sbjct: 547 LTQSG 551
Score = 39.5 bits (88), Expect = 0.012
Identities = 28/118 (23%), Positives = 48/118 (40%)
Frame = +3
Query: 222 CWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNN 401
C +HE + T + LS +K I+ +A G+ H+ + G L + G N
Sbjct: 569 CMSGIINHEAYHEVPYTTSFTLAKQLSFYK----IRTIAPGKTHTAAIDERGRLLTFGCN 624
Query: 402 DVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQL 575
GQLG L + ++CG + ++A + F+WG+ G+L
Sbjct: 625 KCGQLGVGNYKKRLGINLLGGPLGGKQVIRVSCGDEFTIAATDDNHIFAWGNGGNGRL 682
Score = 39.1 bits (87), Expect = 0.015
Identities = 28/97 (28%), Positives = 49/97 (50%), Gaps = 7/97 (7%)
Frame = +3
Query: 441 GKN-PALVETFKD-CTISTIACGLQHSLAIDEWGQPFSW-----GSDSMGQLGNNLGAHA 599
GK+ P ++ K C+ + G H + + ++W G+ GQLG+ A
Sbjct: 355 GKSTPQKLDVIKSGCSARQVCAGNTHFAVVTVEKELYTWVNMQGGTKLHGQLGHGDKASY 414
Query: 600 QDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
+ +PK V+ L K + QV+CG +V +T+ G LY++
Sbjct: 415 R-QPKHVEKLQGKAIRQVSCGDDFTVCVTDEGQLYAF 450
>AY080896-1|AAL87410.1| 979|Homo sapiens NIMA-family kinase NERCC1
protein.
Length = 979
Score = 53.6 bits (123), Expect = 7e-07
Identities = 37/132 (28%), Positives = 63/132 (47%), Gaps = 6/132 (4%)
Frame = +3
Query: 333 VAAGEFHSLYLSNSGHLYSC-----GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIA 497
V AG H ++ LY+ G GQLG ++ + P VE + I ++
Sbjct: 374 VCAGNTHFAVVTVEKELYTWVNMQGGTKLHGQLGHGDKASY-RQPKHVEKLQGKAIHQVS 432
Query: 498 CGLQHSLAIDEWGQPFSWGSDSMGQLG-NNLGAHAQDKPKFVKGLATKNVIQVACGAYHS 674
CG ++ + + GQ +++GSD G +G + + +P + + V QV+CG H
Sbjct: 433 CGDDFTVCVTDEGQLYAFGSDYYGCMGVDKVAGPEVLEPMQLNFFLSNPVEQVSCGDNHV 492
Query: 675 VALTNSGDLYSW 710
V LT + ++YSW
Sbjct: 493 VVLTRNKEVYSW 504
Score = 52.8 bits (121), Expect = 1e-06
Identities = 52/185 (28%), Positives = 85/185 (45%), Gaps = 14/185 (7%)
Frame = +3
Query: 198 LQNYKKMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSG 377
L K+++ WG + L +D + K + K + I AV G + L+ SG
Sbjct: 495 LTRNKEVYSWGCGEYGRLGLDSEEDYYTPQKVDVPK---ALIIVAVQCGCDGTFLLTQSG 551
Query: 378 HLYSCGNNDVGQLG-RQTESDNGKNPA-----------LVETFKDCTISTIACGLQHSLA 521
+ +CG N+ +LG Q S + A L + I TIA G H+ A
Sbjct: 552 KVLACGLNEFNKLGLNQCMSGIINHEAYHEVPYTTSFTLAKQLSFYKIRTIAPGKTHTAA 611
Query: 522 IDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKG--LATKNVIQVACGAYHSVALTNSG 695
IDE G+ ++G + GQLG +G + + + G L K VI+V+CG ++A T+
Sbjct: 612 IDERGRLLTFGCNKCGQLG--VGNYKKRLGINLLGGPLGGKQVIRVSCGDEFTIAATDDN 669
Query: 696 DLYSW 710
+++W
Sbjct: 670 HIFAW 674
Score = 43.6 bits (98), Expect = 7e-04
Identities = 29/125 (23%), Positives = 55/125 (44%), Gaps = 1/125 (0%)
Frame = +3
Query: 324 IQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLG-RQTESDNGKNPALVETFKDCTISTIAC 500
I V+ G+ ++ +++ G LY+ G++ G +G + P + F + ++C
Sbjct: 428 IHQVSCGDDFTVCVTDEGQLYAFGSDYYGCMGVDKVAGPEVLEPMQLNFFLSNPVEQVSC 487
Query: 501 GLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA 680
G H + + + +SWG G+LG + P+ V ++ V CG +
Sbjct: 488 GDNHVVVLTRNKEVYSWGCGEYGRLGLD-SEEDYYTPQKVDVPKALIIVAVQCGCDGTFL 546
Query: 681 LTNSG 695
LT SG
Sbjct: 547 LTQSG 551
Score = 39.5 bits (88), Expect = 0.012
Identities = 28/118 (23%), Positives = 48/118 (40%)
Frame = +3
Query: 222 CWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNN 401
C +HE + T + LS +K I+ +A G+ H+ + G L + G N
Sbjct: 569 CMSGIINHEAYHEVPYTTSFTLAKQLSFYK----IRTIAPGKTHTAAIDERGRLLTFGCN 624
Query: 402 DVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQL 575
GQLG L + ++CG + ++A + F+WG+ G+L
Sbjct: 625 KCGQLGVGNYKKRLGINLLGGPLGGKQVIRVSCGDEFTIAATDDNHIFAWGNGGNGRL 682
Score = 39.1 bits (87), Expect = 0.015
Identities = 28/97 (28%), Positives = 49/97 (50%), Gaps = 7/97 (7%)
Frame = +3
Query: 441 GKN-PALVETFKD-CTISTIACGLQHSLAIDEWGQPFSW-----GSDSMGQLGNNLGAHA 599
GK+ P ++ K C+ + G H + + ++W G+ GQLG+ A
Sbjct: 355 GKSTPQKLDVIKSGCSARQVCAGNTHFAVVTVEKELYTWVNMQGGTKLHGQLGHGDKASY 414
Query: 600 QDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
+ +PK V+ L K + QV+CG +V +T+ G LY++
Sbjct: 415 R-QPKHVEKLQGKAIHQVSCGDDFTVCVTDEGQLYAF 450
>AY048580-1|AAL05428.1| 979|Homo sapiens NIMA-related kinase Nek8
protein.
Length = 979
Score = 53.6 bits (123), Expect = 7e-07
Identities = 37/132 (28%), Positives = 63/132 (47%), Gaps = 6/132 (4%)
Frame = +3
Query: 333 VAAGEFHSLYLSNSGHLYSC-----GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIA 497
V AG H ++ LY+ G GQLG ++ + P VE + I ++
Sbjct: 374 VCAGNTHFAVVTVEKELYTWVNMQGGTKLHGQLGHGDKASY-RQPKHVEKLQGKAIHQVS 432
Query: 498 CGLQHSLAIDEWGQPFSWGSDSMGQLG-NNLGAHAQDKPKFVKGLATKNVIQVACGAYHS 674
CG ++ + + GQ +++GSD G +G + + +P + + V QV+CG H
Sbjct: 433 CGDDFTVCVTDEGQLYAFGSDYYGCMGVDKVAGPEVLEPMQLNFFLSNPVEQVSCGDNHV 492
Query: 675 VALTNSGDLYSW 710
V LT + ++YSW
Sbjct: 493 VVLTRNKEVYSW 504
Score = 52.8 bits (121), Expect = 1e-06
Identities = 52/185 (28%), Positives = 85/185 (45%), Gaps = 14/185 (7%)
Frame = +3
Query: 198 LQNYKKMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSG 377
L K+++ WG + L +D + K + K + I AV G + L+ SG
Sbjct: 495 LTRNKEVYSWGCGEYGRLGLDSEEDYYTPQKVDVPK---ALIIVAVQCGCDGTFLLTQSG 551
Query: 378 HLYSCGNNDVGQLG-RQTESDNGKNPA-----------LVETFKDCTISTIACGLQHSLA 521
+ +CG N+ +LG Q S + A L + I TIA G H+ A
Sbjct: 552 KVLACGLNEFNKLGLNQCMSGIINHEAYHEVPYTTSFTLAKQLSFYKIRTIAPGKTHTAA 611
Query: 522 IDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKG--LATKNVIQVACGAYHSVALTNSG 695
IDE G+ ++G + GQLG +G + + + G L K VI+V+CG ++A T+
Sbjct: 612 IDERGRLLTFGCNKCGQLG--VGNYKKRLGINLLGGPLGGKQVIRVSCGDEFTIAATDDN 669
Query: 696 DLYSW 710
+++W
Sbjct: 670 HIFAW 674
Score = 43.6 bits (98), Expect = 7e-04
Identities = 29/125 (23%), Positives = 55/125 (44%), Gaps = 1/125 (0%)
Frame = +3
Query: 324 IQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLG-RQTESDNGKNPALVETFKDCTISTIAC 500
I V+ G+ ++ +++ G LY+ G++ G +G + P + F + ++C
Sbjct: 428 IHQVSCGDDFTVCVTDEGQLYAFGSDYYGCMGVDKVAGPEVLEPMQLNFFLSNPVEQVSC 487
Query: 501 GLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA 680
G H + + + +SWG G+LG + P+ V ++ V CG +
Sbjct: 488 GDNHVVVLTRNKEVYSWGCGEYGRLGLD-SEEDYYTPQKVDVPKALIIVAVQCGCDGTFL 546
Query: 681 LTNSG 695
LT SG
Sbjct: 547 LTQSG 551
Score = 39.5 bits (88), Expect = 0.012
Identities = 28/118 (23%), Positives = 48/118 (40%)
Frame = +3
Query: 222 CWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNN 401
C +HE + T + LS +K I+ +A G+ H+ + G L + G N
Sbjct: 569 CMSGIINHEAYHEVPYTTSFTLAKQLSFYK----IRTIAPGKTHTAAIDERGRLLTFGCN 624
Query: 402 DVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQL 575
GQLG L + ++CG + ++A + F+WG+ G+L
Sbjct: 625 KCGQLGVGNYKKRLGINLLGGPLGGKQVIRVSCGDEFTIAATDDNHIFAWGNGGNGRL 682
Score = 39.1 bits (87), Expect = 0.015
Identities = 28/97 (28%), Positives = 49/97 (50%), Gaps = 7/97 (7%)
Frame = +3
Query: 441 GKN-PALVETFKD-CTISTIACGLQHSLAIDEWGQPFSW-----GSDSMGQLGNNLGAHA 599
GK+ P ++ K C+ + G H + + ++W G+ GQLG+ A
Sbjct: 355 GKSTPQKLDVIKSGCSARQVCAGNTHFAVVTVEKELYTWVNMQGGTKLHGQLGHGDKASY 414
Query: 600 QDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
+ +PK V+ L K + QV+CG +V +T+ G LY++
Sbjct: 415 R-QPKHVEKLQGKAIHQVSCGDDFTVCVTDEGQLYAF 450
>AC007055-4|AAD31939.1| 414|Homo sapiens protein ( Homo sapiens
chromosome 14 clone BAC 201F1 map 14q24.3, complete
sequence. ).
Length = 414
Score = 53.6 bits (123), Expect = 7e-07
Identities = 37/132 (28%), Positives = 63/132 (47%), Gaps = 6/132 (4%)
Frame = +3
Query: 333 VAAGEFHSLYLSNSGHLYSC-----GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIA 497
V AG H ++ LY+ G GQLG ++ + P VE + I ++
Sbjct: 44 VCAGNTHFAVVTVEKELYTWVNMQGGTKLHGQLGHGDKASY-RQPKHVEKLQGKAIRQVS 102
Query: 498 CGLQHSLAIDEWGQPFSWGSDSMGQLG-NNLGAHAQDKPKFVKGLATKNVIQVACGAYHS 674
CG ++ + + GQ +++GSD G +G + + +P + + V QV+CG H
Sbjct: 103 CGDDFTVCVTDEGQLYAFGSDYYGCMGVDKVAGPEVLEPMQLNFFLSNPVEQVSCGDNHV 162
Query: 675 VALTNSGDLYSW 710
V LT + ++YSW
Sbjct: 163 VVLTRNKEVYSW 174
Score = 52.8 bits (121), Expect = 1e-06
Identities = 52/185 (28%), Positives = 85/185 (45%), Gaps = 14/185 (7%)
Frame = +3
Query: 198 LQNYKKMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSG 377
L K+++ WG + L +D + K + K + I AV G + L+ SG
Sbjct: 165 LTRNKEVYSWGCGEYGRLGLDSEEDYYTPQKVDVPK---ALIIVAVQCGCDGTFLLTQSG 221
Query: 378 HLYSCGNNDVGQLG-RQTESDNGKNPA-----------LVETFKDCTISTIACGLQHSLA 521
+ +CG N+ +LG Q S + A L + I TIA G H+ A
Sbjct: 222 KVLACGLNEFNKLGLNQCMSGIINHEAYHEVPYTTSFTLAKQLSFYKIRTIAPGKTHTAA 281
Query: 522 IDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKG--LATKNVIQVACGAYHSVALTNSG 695
IDE G+ ++G + GQLG +G + + + G L K VI+V+CG ++A T+
Sbjct: 282 IDERGRLLTFGCNKCGQLG--VGNYKKRLGINLLGGPLGGKQVIRVSCGDEFTIAATDDN 339
Query: 696 DLYSW 710
+++W
Sbjct: 340 HIFAW 344
Score = 44.0 bits (99), Expect = 5e-04
Identities = 29/125 (23%), Positives = 56/125 (44%), Gaps = 1/125 (0%)
Frame = +3
Query: 324 IQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLG-RQTESDNGKNPALVETFKDCTISTIAC 500
I+ V+ G+ ++ +++ G LY+ G++ G +G + P + F + ++C
Sbjct: 98 IRQVSCGDDFTVCVTDEGQLYAFGSDYYGCMGVDKVAGPEVLEPMQLNFFLSNPVEQVSC 157
Query: 501 GLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA 680
G H + + + +SWG G+LG + P+ V ++ V CG +
Sbjct: 158 GDNHVVVLTRNKEVYSWGCGEYGRLGLD-SEEDYYTPQKVDVPKALIIVAVQCGCDGTFL 216
Query: 681 LTNSG 695
LT SG
Sbjct: 217 LTQSG 221
Score = 39.5 bits (88), Expect = 0.012
Identities = 28/118 (23%), Positives = 48/118 (40%)
Frame = +3
Query: 222 CWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNN 401
C +HE + T + LS +K I+ +A G+ H+ + G L + G N
Sbjct: 239 CMSGIINHEAYHEVPYTTSFTLAKQLSFYK----IRTIAPGKTHTAAIDERGRLLTFGCN 294
Query: 402 DVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQL 575
GQLG L + ++CG + ++A + F+WG+ G+L
Sbjct: 295 KCGQLGVGNYKKRLGINLLGGPLGGKQVIRVSCGDEFTIAATDDNHIFAWGNGGNGRL 352
Score = 39.1 bits (87), Expect = 0.015
Identities = 28/97 (28%), Positives = 49/97 (50%), Gaps = 7/97 (7%)
Frame = +3
Query: 441 GKN-PALVETFKD-CTISTIACGLQHSLAIDEWGQPFSW-----GSDSMGQLGNNLGAHA 599
GK+ P ++ K C+ + G H + + ++W G+ GQLG+ A
Sbjct: 25 GKSTPQKLDVIKSGCSARQVCAGNTHFAVVTVEKELYTWVNMQGGTKLHGQLGHGDKASY 84
Query: 600 QDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
+ +PK V+ L K + QV+CG +V +T+ G LY++
Sbjct: 85 R-QPKHVEKLQGKAIRQVSCGDDFTVCVTDEGQLYAF 120
>AB082526-1|BAC02704.1| 1011|Homo sapiens KIAA1995 protein protein.
Length = 1011
Score = 53.6 bits (123), Expect = 7e-07
Identities = 37/132 (28%), Positives = 63/132 (47%), Gaps = 6/132 (4%)
Frame = +3
Query: 333 VAAGEFHSLYLSNSGHLYSC-----GNNDVGQLGRQTESDNGKNPALVETFKDCTISTIA 497
V AG H ++ LY+ G GQLG ++ + P VE + I ++
Sbjct: 406 VCAGNTHFAVVTVEKELYTWVNMQGGTKLHGQLGHGDKASY-RQPKHVEKLQGKAIHQVS 464
Query: 498 CGLQHSLAIDEWGQPFSWGSDSMGQLG-NNLGAHAQDKPKFVKGLATKNVIQVACGAYHS 674
CG ++ + + GQ +++GSD G +G + + +P + + V QV+CG H
Sbjct: 465 CGDDFTVCVTDEGQLYAFGSDYYGCMGVDKVAGPEVLEPMQLNFFLSNPVEQVSCGDNHV 524
Query: 675 VALTNSGDLYSW 710
V LT + ++YSW
Sbjct: 525 VVLTRNKEVYSW 536
Score = 52.8 bits (121), Expect = 1e-06
Identities = 52/185 (28%), Positives = 85/185 (45%), Gaps = 14/185 (7%)
Frame = +3
Query: 198 LQNYKKMFCWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSG 377
L K+++ WG + L +D + K + K + I AV G + L+ SG
Sbjct: 527 LTRNKEVYSWGCGEYGRLGLDSEEDYYTPQKVDVPK---ALIIVAVQCGCDGTFLLTQSG 583
Query: 378 HLYSCGNNDVGQLG-RQTESDNGKNPA-----------LVETFKDCTISTIACGLQHSLA 521
+ +CG N+ +LG Q S + A L + I TIA G H+ A
Sbjct: 584 KVLACGLNEFNKLGLNQCMSGIINHEAYHEVPYTTSFTLAKQLSFYKIRTIAPGKTHTAA 643
Query: 522 IDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKG--LATKNVIQVACGAYHSVALTNSG 695
IDE G+ ++G + GQLG +G + + + G L K VI+V+CG ++A T+
Sbjct: 644 IDERGRLLTFGCNKCGQLG--VGNYKKRLGINLLGGPLGGKQVIRVSCGDEFTIAATDDN 701
Query: 696 DLYSW 710
+++W
Sbjct: 702 HIFAW 706
Score = 43.6 bits (98), Expect = 7e-04
Identities = 29/125 (23%), Positives = 55/125 (44%), Gaps = 1/125 (0%)
Frame = +3
Query: 324 IQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLG-RQTESDNGKNPALVETFKDCTISTIAC 500
I V+ G+ ++ +++ G LY+ G++ G +G + P + F + ++C
Sbjct: 460 IHQVSCGDDFTVCVTDEGQLYAFGSDYYGCMGVDKVAGPEVLEPMQLNFFLSNPVEQVSC 519
Query: 501 GLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA 680
G H + + + +SWG G+LG + P+ V ++ V CG +
Sbjct: 520 GDNHVVVLTRNKEVYSWGCGEYGRLGLD-SEEDYYTPQKVDVPKALIIVAVQCGCDGTFL 578
Query: 681 LTNSG 695
LT SG
Sbjct: 579 LTQSG 583
Score = 39.5 bits (88), Expect = 0.012
Identities = 28/118 (23%), Positives = 48/118 (40%)
Frame = +3
Query: 222 CWGNATHHELCIDGSQITDLVIKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNN 401
C +HE + T + LS +K I+ +A G+ H+ + G L + G N
Sbjct: 601 CMSGIINHEAYHEVPYTTSFTLAKQLSFYK----IRTIAPGKTHTAAIDERGRLLTFGCN 656
Query: 402 DVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQL 575
GQLG L + ++CG + ++A + F+WG+ G+L
Sbjct: 657 KCGQLGVGNYKKRLGINLLGGPLGGKQVIRVSCGDEFTIAATDDNHIFAWGNGGNGRL 714
Score = 39.1 bits (87), Expect = 0.015
Identities = 28/97 (28%), Positives = 49/97 (50%), Gaps = 7/97 (7%)
Frame = +3
Query: 441 GKN-PALVETFKD-CTISTIACGLQHSLAIDEWGQPFSW-----GSDSMGQLGNNLGAHA 599
GK+ P ++ K C+ + G H + + ++W G+ GQLG+ A
Sbjct: 387 GKSTPQKLDVIKSGCSARQVCAGNTHFAVVTVEKELYTWVNMQGGTKLHGQLGHGDKASY 446
Query: 600 QDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
+ +PK V+ L K + QV+CG +V +T+ G LY++
Sbjct: 447 R-QPKHVEKLQGKAIHQVSCGDDFTVCVTDEGQLYAF 482
>AF225404-1|AAO27482.1| 259|Homo sapiens HERC2 protein.
Length = 259
Score = 44.4 bits (100), Expect = 4e-04
Identities = 34/121 (28%), Positives = 55/121 (45%), Gaps = 2/121 (1%)
Frame = +3
Query: 354 SLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEW 533
+L SG +Y G+N GQLG E K P E + G Q A+
Sbjct: 120 TLSAGGSGTIYGWGHNHRGQLG-GIEGAKVKVPTPCEALATLRPVQLIGGEQTLFAVTAD 178
Query: 534 GQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVA--CGAYHSVALTNSGDLYS 707
G+ ++ G + G+LG G + P ++ + + +VA G H +AL++ G++YS
Sbjct: 179 GKLYATGYGAGGRLGIG-GTESVSTPTLLESIQHVFIKKVAVNSGGKHCLALSSEGEVYS 237
Query: 708 W 710
W
Sbjct: 238 W 238
>AL359257-2|CAI39759.1| 4640|Homo sapiens AC001226.5 protein.
Length = 4640
Score = 40.7 bits (91), Expect = 0.005
Identities = 33/130 (25%), Positives = 59/130 (45%), Gaps = 2/130 (1%)
Frame = +3
Query: 327 QAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTI--AC 500
QA+A H L + + G+ G+ G + S P F DC + + +C
Sbjct: 854 QALARLRSHPAQLKHKRDKHKDGS---GERGEKDASKITTYPPGSVRF-DCELRAVQVSC 909
Query: 501 GLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA 680
G HS+ + E G +++G GQLG+ +++ P V+ L + QV G+ H+
Sbjct: 910 GFHHSVVLMENGDVYTFGYGQHGQLGHG-DVNSRGCPTLVQALPGPST-QVTAGSNHTAV 967
Query: 681 LTNSGDLYSW 710
L G ++++
Sbjct: 968 LLMDGQVFTF 977
Score = 35.5 bits (78), Expect = 0.19
Identities = 22/68 (32%), Positives = 33/68 (48%), Gaps = 3/68 (4%)
Frame = +3
Query: 510 HSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQD---KPKFVKGLATKNVIQVACGAYHSVA 680
H+L + E G F GS S G+ G + + Q KPK + + K V+ AC S
Sbjct: 555 HALLVAEDGSIFFTGSASKGEDGESTKSRRQSKPYKPKKIIKMEGKIVVYTACNNGSSSV 614
Query: 681 LTNSGDLY 704
++ G+LY
Sbjct: 615 ISKDGELY 622
>AL159158-1|CAI16842.1| 4640|Homo sapiens AC001226.5 protein.
Length = 4640
Score = 40.7 bits (91), Expect = 0.005
Identities = 33/130 (25%), Positives = 59/130 (45%), Gaps = 2/130 (1%)
Frame = +3
Query: 327 QAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTI--AC 500
QA+A H L + + G+ G+ G + S P F DC + + +C
Sbjct: 854 QALARLRSHPAQLKHKRDKHKDGS---GERGEKDASKITTYPPGSVRF-DCELRAVQVSC 909
Query: 501 GLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA 680
G HS+ + E G +++G GQLG+ +++ P V+ L + QV G+ H+
Sbjct: 910 GFHHSVVLMENGDVYTFGYGQHGQLGHG-DVNSRGCPTLVQALPGPST-QVTAGSNHTAV 967
Query: 681 LTNSGDLYSW 710
L G ++++
Sbjct: 968 LLMDGQVFTF 977
Score = 35.5 bits (78), Expect = 0.19
Identities = 22/68 (32%), Positives = 33/68 (48%), Gaps = 3/68 (4%)
Frame = +3
Query: 510 HSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQD---KPKFVKGLATKNVIQVACGAYHSVA 680
H+L + E G F GS S G+ G + + Q KPK + + K V+ AC S
Sbjct: 555 HALLVAEDGSIFFTGSASKGEDGESTKSRRQSKPYKPKKIIKMEGKIVVYTACNNGSSSV 614
Query: 681 LTNSGDLY 704
++ G+LY
Sbjct: 615 ISKDGELY 622
>AL159154-1|CAH73736.1| 4640|Homo sapiens AC001226.5 protein.
Length = 4640
Score = 40.7 bits (91), Expect = 0.005
Identities = 33/130 (25%), Positives = 59/130 (45%), Gaps = 2/130 (1%)
Frame = +3
Query: 327 QAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTI--AC 500
QA+A H L + + G+ G+ G + S P F DC + + +C
Sbjct: 854 QALARLRSHPAQLKHKRDKHKDGS---GERGEKDASKITTYPPGSVRF-DCELRAVQVSC 909
Query: 501 GLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA 680
G HS+ + E G +++G GQLG+ +++ P V+ L + QV G+ H+
Sbjct: 910 GFHHSVVLMENGDVYTFGYGQHGQLGHG-DVNSRGCPTLVQALPGPST-QVTAGSNHTAV 967
Query: 681 LTNSGDLYSW 710
L G ++++
Sbjct: 968 LLMDGQVFTF 977
Score = 35.5 bits (78), Expect = 0.19
Identities = 22/68 (32%), Positives = 33/68 (48%), Gaps = 3/68 (4%)
Frame = +3
Query: 510 HSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQD---KPKFVKGLATKNVIQVACGAYHSVA 680
H+L + E G F GS S G+ G + + Q KPK + + K V+ AC S
Sbjct: 555 HALLVAEDGSIFFTGSASKGEDGESTKSRRQSKPYKPKKIIKMEGKIVVYTACNNGSSSV 614
Query: 681 LTNSGDLY 704
++ G+LY
Sbjct: 615 ISKDGELY 622
>AF075587-1|AAC39928.1| 4641|Homo sapiens protein associated with Myc
protein.
Length = 4641
Score = 40.7 bits (91), Expect = 0.005
Identities = 32/130 (24%), Positives = 60/130 (46%), Gaps = 2/130 (1%)
Frame = +3
Query: 327 QAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTI--AC 500
QA+A H ++ + + G+ G+ G + S P F DC + + +C
Sbjct: 854 QALARLRSHPAHVKHKRDKHKDGS---GERGEKDASKITTYPPGSVRF-DCELRAVQVSC 909
Query: 501 GLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVA 680
G HS+ + E G +++G GQLG+ +++ P V+ L + QV G+ H+
Sbjct: 910 GFHHSVVLMENGDVYTFGYGQHGQLGHG-DVNSRGCPTLVQALPGPST-QVTAGSNHTAV 967
Query: 681 LTNSGDLYSW 710
L G ++++
Sbjct: 968 LLMDGQVFTF 977
Score = 36.7 bits (81), Expect = 0.082
Identities = 22/68 (32%), Positives = 34/68 (50%), Gaps = 3/68 (4%)
Frame = +3
Query: 510 HSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQD---KPKFVKGLATKNVIQVACGAYHSVA 680
H+L + E G F GS S G+ G ++ + Q KPK + + K V+ AC S
Sbjct: 555 HALLVAEDGSIFFTGSASKGEDGESIKSRRQSKPYKPKKIIKMEGKIVVYTACNNGSSSV 614
Query: 681 LTNSGDLY 704
++ G+LY
Sbjct: 615 ISKDGELY 622
>BC113826-1|AAI13827.1| 244|Homo sapiens RCCD1 protein protein.
Length = 244
Score = 39.9 bits (89), Expect = 0.009
Identities = 18/51 (35%), Positives = 31/51 (60%)
Frame = +3
Query: 558 DSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHSVALTNSGDLYSW 710
D GQLG+ A+ +P+ ++ L + +VA G +HSV ++ +GD+Y W
Sbjct: 53 DPHGQLGHGT-LEAELEPRLLEALQGLVMAEVAAGGWHSVCVSETGDIYIW 102
Score = 37.9 bits (84), Expect = 0.035
Identities = 21/77 (27%), Positives = 38/77 (49%), Gaps = 2/77 (2%)
Frame = +3
Query: 450 PALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGL 629
PAL++ +CG +H+ + G+ ++WG GQLG+ + D+P+ V+
Sbjct: 159 PALLDLPMGSDAVKASCGSRHTAVVTRTGELYTWGWGKYGQLGHE-DTTSLDRPRRVEYF 217
Query: 630 ATK--NVIQVACGAYHS 674
K V V CG +++
Sbjct: 218 VDKQLQVKAVTCGPWNT 234
Score = 37.1 bits (82), Expect = 0.062
Identities = 19/56 (33%), Positives = 29/56 (51%)
Frame = +3
Query: 408 GQLGRQTESDNGKNPALVETFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQL 575
GQLG T + P L+E + ++ +A G HS+ + E G + WG + GQL
Sbjct: 56 GQLGHGT-LEAELEPRLLEALQGLVMAEVAAGGWHSVCVSETGDIYIWGWNESGQL 110
Score = 37.1 bits (82), Expect = 0.062
Identities = 35/142 (24%), Positives = 64/142 (45%)
Frame = +3
Query: 285 IKPTLSKWKESDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVE 464
++P L + + + VAAG +HS+ +S +G +Y G N+ GQL T + L E
Sbjct: 67 LEPRLLEALQGLVMAEVAAGGWHSVCVSETGDIYIWGWNESGQLALPTRN-------LAE 119
Query: 465 TFKDCTISTIACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNV 644
+ T++ A L ++ Q G G + Q P + +
Sbjct: 120 DGE--TVAREATELN-----EDGSQVKRTGGAEDGAPAPFIA--VQPFPALLDLPMGSDA 170
Query: 645 IQVACGAYHSVALTNSGDLYSW 710
++ +CG+ H+ +T +G+LY+W
Sbjct: 171 VKASCGSRHTAVVTRTGELYTW 192
Score = 33.5 bits (73), Expect = 0.76
Identities = 20/65 (30%), Positives = 34/65 (52%), Gaps = 2/65 (3%)
Frame = +3
Query: 315 SDHIQAVAAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETF--KDCTIS 488
SD ++A + G H+ ++ +G LY+ G GQLG + ++ + P VE F K +
Sbjct: 168 SDAVKA-SCGSRHTAVVTRTGELYTWGWGKYGQLGHE-DTTSLDRPRRVEYFVDKQLQVK 225
Query: 489 TIACG 503
+ CG
Sbjct: 226 AVTCG 230
>BC067293-1|AAH67293.1| 580|Homo sapiens F-box protein 24 protein.
Length = 580
Score = 34.3 bits (75), Expect = 0.44
Identities = 23/65 (35%), Positives = 32/65 (49%)
Frame = +3
Query: 336 AAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHS 515
A G H + G ++ GNN GQLG + D G+ P V + I T+ CGL HS
Sbjct: 363 ALGYNHLGLVDEFGRIFMQGNNRYGQLGTGDKMDRGE-PTQV-CYLQRPI-TLWCGLNHS 419
Query: 516 LAIDE 530
L + +
Sbjct: 420 LVLSQ 424
Score = 33.9 bits (74), Expect = 0.58
Identities = 20/68 (29%), Positives = 33/68 (48%)
Frame = +3
Query: 495 ACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHS 674
A G H +DE+G+ F G++ GQLG D+ + + + I + CG HS
Sbjct: 363 ALGYNHLGLVDEFGRIFMQGNNRYGQLGT---GDKMDRGEPTQVCYLQRPITLWCGLNHS 419
Query: 675 VALTNSGD 698
+ L+ S +
Sbjct: 420 LVLSQSSE 427
>AC069281-1|AAP21863.1| 580|Homo sapiens unknown protein.
Length = 580
Score = 34.3 bits (75), Expect = 0.44
Identities = 23/65 (35%), Positives = 32/65 (49%)
Frame = +3
Query: 336 AAGEFHSLYLSNSGHLYSCGNNDVGQLGRQTESDNGKNPALVETFKDCTISTIACGLQHS 515
A G H + G ++ GNN GQLG + D G+ P V + I T+ CGL HS
Sbjct: 363 ALGYNHLGLVDEFGRIFMQGNNRYGQLGTGDKMDRGE-PTQV-CYLQRPI-TLWCGLNHS 419
Query: 516 LAIDE 530
L + +
Sbjct: 420 LVLSQ 424
Score = 33.9 bits (74), Expect = 0.58
Identities = 20/68 (29%), Positives = 33/68 (48%)
Frame = +3
Query: 495 ACGLQHSLAIDEWGQPFSWGSDSMGQLGNNLGAHAQDKPKFVKGLATKNVIQVACGAYHS 674
A G H +DE+G+ F G++ GQLG D+ + + + I + CG HS
Sbjct: 363 ALGYNHLGLVDEFGRIFMQGNNRYGQLGT---GDKMDRGEPTQVCYLQRPITLWCGLNHS 419
Query: 675 VALTNSGD 698
+ L+ S +
Sbjct: 420 LVLSQSSE 427
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 101,893,313
Number of Sequences: 237096
Number of extensions: 2106234
Number of successful extensions: 5946
Number of sequences better than 10.0: 101
Number of HSP's better than 10.0 without gapping: 4793
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5422
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8287202872
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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