Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= bmov11l09
(670 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_O60921 Cluster: Checkpoint protein HUS1; n=29; Euteleos... 152 8e-36
UniRef50_Q4S227 Cluster: Chromosome undetermined SCAF14764, whol... 151 2e-35
UniRef50_A7RGK3 Cluster: Predicted protein; n=1; Nematostella ve... 150 3e-35
UniRef50_UPI0000588F5E Cluster: PREDICTED: similar to Hus1 prote... 145 7e-34
UniRef50_UPI00015B602E Cluster: PREDICTED: similar to Hus1 prote... 140 4e-32
UniRef50_Q9VN60 Cluster: CG2525-PA; n=4; Sophophora|Rep: CG2525-... 136 5e-31
UniRef50_UPI00015A4C81 Cluster: Checkpoint protein HUS1B (hHUS1B... 130 3e-29
UniRef50_Q8NHY5 Cluster: Checkpoint protein HUS1B; n=8; Euarchon... 105 1e-21
UniRef50_Q177M4 Cluster: Mitotic and DNA damage checkpoint prote... 99 8e-20
UniRef50_Q5DGF4 Cluster: SJCHGC09161 protein; n=2; Platyhelminth... 66 9e-18
UniRef50_Q9NG93 Cluster: LIG1; n=1; Physarum polycephalum|Rep: L... 66 5e-10
UniRef50_Q54NC0 Cluster: Checkpoint clamp complex protein; n=1; ... 65 2e-09
UniRef50_Q55LM4 Cluster: Putative uncharacterized protein; n=1; ... 63 5e-09
UniRef50_Q9XYP0 Cluster: Hus1-like protein; n=2; Caenorhabditis|... 61 3e-08
UniRef50_Q9HEC8 Cluster: Related to mitotic and DNA damage check... 60 6e-08
UniRef50_A2EXY8 Cluster: Hus1-like protein; n=1; Trichomonas vag... 52 1e-05
UniRef50_UPI0000F2CB2B Cluster: PREDICTED: similar to HUS1 check... 50 5e-05
UniRef50_P78955 Cluster: Checkpoint protein hus1; n=1; Schizosac... 45 0.002
UniRef50_Q6CUH3 Cluster: Kluyveromyces lactis strain NRRL Y-1140... 40 0.041
UniRef50_Q74ZB0 Cluster: DNA damage checkpoint control protein M... 40 0.041
UniRef50_Q92380 Cluster: Meiotic recombination protein rec11; n=... 36 0.67
UniRef50_Q8I5V9 Cluster: Putative uncharacterized protein; n=7; ... 36 1.2
UniRef50_UPI00006CD1B8 Cluster: hypothetical protein TTHERM_0012... 34 2.7
UniRef50_Q2GXM2 Cluster: Putative uncharacterized protein; n=5; ... 33 4.7
UniRef50_A1DLN4 Cluster: Cell cycle checkpoint protein (Hus1), p... 33 4.7
UniRef50_UPI000051039E Cluster: COG0477: Permeases of the major ... 33 6.2
UniRef50_A3LW20 Cluster: Predicted protein; n=4; Saccharomycetal... 33 8.2
UniRef50_Q93SN7 Cluster: Phycoerythrobilin:ferredoxin oxidoreduc... 33 8.2
>UniRef50_O60921 Cluster: Checkpoint protein HUS1; n=29;
Euteleostomi|Rep: Checkpoint protein HUS1 - Homo sapiens
(Human)
Length = 280
Score = 152 bits (368), Expect = 8e-36
Identities = 74/168 (44%), Positives = 110/168 (65%)
Frame = +1
Query: 166 MKFRAVMNNSSPIREFSTIVSTISKLSKECVLRIADDMLYFIVSDENTGPAPPVLWCEIP 345
MKFRA + + + + F+ I + I+KL+K C LRI+ D L FI+ D+ +WCE+
Sbjct: 1 MKFRAKIVDGACLNHFTRISNMIAKLAKTCTLRISPDKLNFILCDKLANGGVS-MWCELE 59
Query: 346 QSVFFSEYQLVGMDETHQDIYLGLNSGNLARSFVSLKNVKSLKMKLTKKQCPCLTLEIEV 525
Q FF+E+Q+ G+ + +IYL L S NL+R+ + +N ++LK+KLT K PCLT+ +E+
Sbjct: 60 QENFFNEFQMEGVSAENNEIYLELTSENLSRALKTAQNARALKIKLTNKHFPCLTVSVEL 119
Query: 526 PSTTSHQTRQIVHDIPVAVVPWKNWPDFYEPRVPDPDISIELPSLKQL 669
S +S +R + HDIP+ V+P K W D EP VPDPD+SI LP LK +
Sbjct: 120 LSMSS-SSRIVTHDIPIKVIPRKLWKDLQEPVVPDPDVSIYLPVLKTM 166
>UniRef50_Q4S227 Cluster: Chromosome undetermined SCAF14764, whole
genome shotgun sequence; n=2; Tetraodontidae|Rep:
Chromosome undetermined SCAF14764, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 312
Score = 151 bits (365), Expect = 2e-35
Identities = 72/168 (42%), Positives = 108/168 (64%)
Frame = +1
Query: 166 MKFRAVMNNSSPIREFSTIVSTISKLSKECVLRIADDMLYFIVSDENTGPAPPVLWCEIP 345
MKFR + N + + F+ +++TISKL++ CVLR+ D L+F++S + T +WCE+
Sbjct: 1 MKFRGKIVNVACLNHFTRVITTISKLARSCVLRLTPDNLFFVLSGKVTNGGVS-MWCELA 59
Query: 346 QSVFFSEYQLVGMDETHQDIYLGLNSGNLARSFVSLKNVKSLKMKLTKKQCPCLTLEIEV 525
Q F EYQ+ G+ +I L + NL R+ +++N KS+K+KLT K CPCLT+ E+
Sbjct: 60 QGNIFDEYQMEGVSSEDNEICLEVAPDNLFRALKTIQNAKSVKVKLTNKHCPCLTIAAEL 119
Query: 526 PSTTSHQTRQIVHDIPVAVVPWKNWPDFYEPRVPDPDISIELPSLKQL 669
P T S+ +R + HDIPV V+P + W +F EP VPD +SI LP LK +
Sbjct: 120 P-TLSNVSRVVTHDIPVDVIPRRLWHEFKEPSVPDFHVSIYLPPLKTM 166
>UniRef50_A7RGK3 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 281
Score = 150 bits (364), Expect = 3e-35
Identities = 72/168 (42%), Positives = 111/168 (66%)
Frame = +1
Query: 166 MKFRAVMNNSSPIREFSTIVSTISKLSKECVLRIADDMLYFIVSDENTGPAPPVLWCEIP 345
M+FRA + + S ++ F+ ++ TIS+++K LR+ LYFI +D +WCE+
Sbjct: 1 MRFRAKIIDLSCMQRFTRVLGTISRMAKTATLRLTPTKLYFIFAD-TVASGGISIWCELN 59
Query: 346 QSVFFSEYQLVGMDETHQDIYLGLNSGNLARSFVSLKNVKSLKMKLTKKQCPCLTLEIEV 525
Q F EY++ G DET+ +IYL L NL+R+ S N +++K+KLTKK PC+T EI +
Sbjct: 60 QCNIFDEYRIEGTDETN-NIYLELIPENLSRAMRSASNAQAVKIKLTKKHVPCITFEIIL 118
Query: 526 PSTTSHQTRQIVHDIPVAVVPWKNWPDFYEPRVPDPDISIELPSLKQL 669
PS ++H TR + HD+PV+V+P +NW ++ EP +PD D+SI +P LK L
Sbjct: 119 PSLSAH-TRTVTHDVPVSVIPQRNWDEYAEPNMPDVDVSIYMPPLKVL 165
>UniRef50_UPI0000588F5E Cluster: PREDICTED: similar to Hus1 protein;
n=2; Strongylocentrotus purpuratus|Rep: PREDICTED:
similar to Hus1 protein - Strongylocentrotus purpuratus
Length = 280
Score = 145 bits (352), Expect = 7e-34
Identities = 70/166 (42%), Positives = 110/166 (66%)
Frame = +1
Query: 166 MKFRAVMNNSSPIREFSTIVSTISKLSKECVLRIADDMLYFIVSDENTGPAPPVLWCEIP 345
M+FRA + + I +F+ +V TI+KL++ CVLRI D +YFI++D+ + LWC++
Sbjct: 1 MRFRAKIFDVGTIEQFTRVVGTIAKLTQLCVLRITSDRMYFILNDK---VSKGHLWCDLQ 57
Query: 346 QSVFFSEYQLVGMDETHQDIYLGLNSGNLARSFVSLKNVKSLKMKLTKKQCPCLTLEIEV 525
FSE+ + G+ E +IY+ +N +L R+ + + KS+K+KLTKK PCL+L++E+
Sbjct: 58 ALNLFSEFSMEGIAEDANEIYMEVNPDDLLRALKTAQTAKSVKIKLTKKFSPCLSLDVEL 117
Query: 526 PSTTSHQTRQIVHDIPVAVVPWKNWPDFYEPRVPDPDISIELPSLK 663
PS T H +R I HDIPV V+P + W ++ EP +PD D +I +P LK
Sbjct: 118 PSRTGH-SRTITHDIPVIVMPRRQWEEYSEPTLPDFDATICMPPLK 162
>UniRef50_UPI00015B602E Cluster: PREDICTED: similar to Hus1 protein;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to Hus1
protein - Nasonia vitripennis
Length = 268
Score = 140 bits (338), Expect = 4e-32
Identities = 67/163 (41%), Positives = 107/163 (65%), Gaps = 1/163 (0%)
Frame = +1
Query: 184 MNNSSPIREFSTIVSTISKLSKECVLRIADDMLYFIVSDENTGPAPPVLWCEIPQSVFFS 363
M+++ +R+F+ + +TI+++SK+CVLR+ D +YF +DE+T P++W + Q+ FF
Sbjct: 1 MDDAGAMRDFTNVATTIARMSKQCVLRLTQDAVYFNAADEST----PMVWTRLDQAHFFR 56
Query: 364 EYQLVGMDETHQDIYLGLNSGNLARSFVSLKN-VKSLKMKLTKKQCPCLTLEIEVPSTTS 540
EY + G E +IY+ LN+ L++S ++KN KS+K+KLT KQ C+T IE+PS S
Sbjct: 57 EYLVEGKSEQFNEIYMELNTAMLSKSASTIKNSAKSVKIKLTNKQQACITFAIELPS-IS 115
Query: 541 HQTRQIVHDIPVAVVPWKNWPDFYEPRVPDPDISIELPSLKQL 669
++R VHDIPV +V K W ++ EP DIS+++P K L
Sbjct: 116 AESRLCVHDIPVTIVSQKRWSEYNEPHYDKFDISLQMPQFKHL 158
>UniRef50_Q9VN60 Cluster: CG2525-PA; n=4; Sophophora|Rep: CG2525-PA
- Drosophila melanogaster (Fruit fly)
Length = 278
Score = 136 bits (329), Expect = 5e-31
Identities = 61/170 (35%), Positives = 109/170 (64%), Gaps = 2/170 (1%)
Frame = +1
Query: 166 MKFRAVMNNSSPIREFSTIVSTISKLSKECVLRIADDMLYFIVSDENTGPAPPVLWCEIP 345
MKFRA+M + ++EF IV+T++KL+K+CV+ + ++FIV+++ + A P++W I
Sbjct: 1 MKFRALMQDPLYMKEFQAIVATLTKLAKDCVMILGSRQMHFIVNEDQSSAASPLVWAGIT 60
Query: 346 QSVFFSEYQLVGMDETHQDIYLGLNSGNLARSFVSLK--NVKSLKMKLTKKQCPCLTLEI 519
+F EY++ + I LG++S NL R+ L+ V S K+KL + Q PC+++
Sbjct: 61 AEEYFPEYRMEAAHPDQEYIVLGVSSANLGRALSVLRGGGVNSCKLKLQRIQFPCISVIA 120
Query: 520 EVPSTTSHQTRQIVHDIPVAVVPWKNWPDFYEPRVPDPDISIELPSLKQL 669
V +++S + R++VHD+PV ++P +W + PRVP+ +++ LPSL+ L
Sbjct: 121 SVLTSSSTEAREVVHDVPVTIIPGSDWSAYVVPRVPNSQLALGLPSLRLL 170
>UniRef50_UPI00015A4C81 Cluster: Checkpoint protein HUS1B (hHUS1B).;
n=1; Danio rerio|Rep: Checkpoint protein HUS1B (hHUS1B).
- Danio rerio
Length = 231
Score = 130 bits (314), Expect = 3e-29
Identities = 64/152 (42%), Positives = 96/152 (63%)
Frame = +1
Query: 166 MKFRAVMNNSSPIREFSTIVSTISKLSKECVLRIADDMLYFIVSDENTGPAPPVLWCEIP 345
MKFRA + + + F+ + +T+S L+ CVLR+ D LYF++S +WCE+
Sbjct: 1 MKFRAKIVDVGCLNHFTRVFNTVSXLTCACVLRLTCDHLYFVLSGR-VATGGVSMWCELL 59
Query: 346 QSVFFSEYQLVGMDETHQDIYLGLNSGNLARSFVSLKNVKSLKMKLTKKQCPCLTLEIEV 525
Q FF E+QL G+ +I+L + NL+R+ + +N KS+K+KLTKK CPCLTL E+
Sbjct: 60 QVNFFDEFQLEGVSADANEIFLEVAPENLSRALKTAQNAKSVKIKLTKKSCPCLTLAAEL 119
Query: 526 PSTTSHQTRQIVHDIPVAVVPWKNWPDFYEPR 621
PS +S +R + HD+PV V+P + W DF EP+
Sbjct: 120 PSLSS-LSRVVTHDLPVDVIPRRLWHDFREPQ 150
>UniRef50_Q8NHY5 Cluster: Checkpoint protein HUS1B; n=8;
Euarchontoglires|Rep: Checkpoint protein HUS1B - Homo
sapiens (Human)
Length = 278
Score = 105 bits (251), Expect = 1e-21
Identities = 59/168 (35%), Positives = 94/168 (55%)
Frame = +1
Query: 166 MKFRAVMNNSSPIREFSTIVSTISKLSKECVLRIADDMLYFIVSDENTGPAPPVLWCEIP 345
MKFRA + + F + T+++L+K CVLR+ D L F + G LWCE+
Sbjct: 1 MKFRAKITGKGCLELFIHVSGTVARLAKVCVLRVRPDSLCFGPAGSG-GLHEARLWCEVR 59
Query: 346 QSVFFSEYQLVGMDETHQDIYLGLNSGNLARSFVSLKNVKSLKMKLTKKQCPCLTLEIEV 525
Q F ++++ G+ E +I+L L + +L+R+ S SLK++LT K+ P LT+ +E+
Sbjct: 60 QGAF-QQFRMEGVSEDLDEIHLELTAEHLSRAARSAAGASSLKLQLTHKRRPSLTVAVEL 118
Query: 526 PSTTSHQTRQIVHDIPVAVVPWKNWPDFYEPRVPDPDISIELPSLKQL 669
S+ + R +VHD+PV V+P + W D P + D SI LP + L
Sbjct: 119 VSSLG-RARSVVHDLPVRVLPRRVWRDCLPPSLRASDASIRLPRWRTL 165
>UniRef50_Q177M4 Cluster: Mitotic and DNA damage checkpoint protein
hus1; n=2; Culicidae|Rep: Mitotic and DNA damage
checkpoint protein hus1 - Aedes aegypti (Yellowfever
mosquito)
Length = 296
Score = 99.1 bits (236), Expect = 8e-20
Identities = 63/175 (36%), Positives = 94/175 (53%), Gaps = 7/175 (4%)
Frame = +1
Query: 166 MKFRAVMNNSSPIREFSTIVSTISKLSKECVLRIADDMLYFIVSDENTGPAPPVLWCEIP 345
MKFRAV+ ++ +RE IV+T S++S+ + I + I+ E A LWCEI
Sbjct: 1 MKFRAVITDTLCMRELLDIVTTFSRISRNIAINIQPKKV--IIQIEGDVEAGQCLWCEID 58
Query: 346 ---QSVFFSEYQLVGMDETHQDIYLGLNSGNL--ARSFVSLKNVKSLKMKLTKKQCPCLT 510
+S FFSE+ + G+DE H IYL + NL A S+ ++ +KMKL K CL
Sbjct: 59 ATDRSGFFSEFVMDGVDEQHNQIYLMAAASNLVQALSYTRNNSMDYVKMKLVKTDVACLA 118
Query: 511 LEIE--VPSTTSHQTRQIVHDIPVAVVPWKNWPDFYEPRVPDPDISIELPSLKQL 669
+E+ V + + ++ H IPV VVP W +F P D+++ LPS+K L
Sbjct: 119 VEMSGIVHNESDVMNPKVQHQIPVTVVPRSEWSNFDLPLDMVYDLTVMLPSVKSL 173
>UniRef50_Q5DGF4 Cluster: SJCHGC09161 protein; n=2;
Platyhelminthes|Rep: SJCHGC09161 protein - Schistosoma
japonicum (Blood fluke)
Length = 352
Score = 66.5 bits (155), Expect(2) = 9e-18
Identities = 35/86 (40%), Positives = 53/86 (61%), Gaps = 1/86 (1%)
Frame = +1
Query: 415 LNSGNLARSF-VSLKNVKSLKMKLTKKQCPCLTLEIEVPSTTSHQTRQIVHDIPVAVVPW 591
+ S +L +F S+ + LK+KL +++ PCL +E+E S T ++R + H IPV VVP
Sbjct: 123 IGSNSLTGNFDPSICRLLGLKIKLVRRKTPCLAIELEQSSVTG-RSRSVWHFIPVQVVPP 181
Query: 592 KNWPDFYEPRVPDPDISIELPSLKQL 669
+ W +F EP PD D+SI P +K L
Sbjct: 182 RLWDEFIEPPDPDFDVSIFFPPVKTL 207
Score = 46.4 bits (105), Expect(2) = 9e-18
Identities = 26/84 (30%), Positives = 40/84 (47%)
Frame = +1
Query: 166 MKFRAVMNNSSPIREFSTIVSTISKLSKECVLRIADDMLYFIVSDENTGPAPPVLWCEIP 345
MKFR N+ I FS IV ++ L+K +L + L F++ E WC++
Sbjct: 1 MKFRIKTNDPGCIEYFSNIVQMVAGLAKNVILHLNKGQLSFVIK-ERVVFGGITAWCDLE 59
Query: 346 QSVFFSEYQLVGMDETHQDIYLGL 417
+V FSE G+ +I+L L
Sbjct: 60 HAVLFSERICEGISPDQDEIFLEL 83
>UniRef50_Q9NG93 Cluster: LIG1; n=1; Physarum polycephalum|Rep: LIG1
- Physarum polycephalum (Slime mold)
Length = 220
Score = 66.5 bits (155), Expect = 5e-10
Identities = 43/154 (27%), Positives = 77/154 (50%), Gaps = 1/154 (0%)
Frame = +1
Query: 211 FSTIVSTISKLSKECVLRIADDMLYFIVSDENTGPAPPVLWCEIPQSVFFSEYQLVGMDE 390
F IV + K++KECV + + I++++ T +W ++ F EY++ ++
Sbjct: 13 FQKIVLAVEKINKECVFFLTPKEIQLILTNDVTDGMQ--VWSGASVNLLFDEYRIESLN- 69
Query: 391 THQDIYLGLNSGNLARSFVSLKNVKSLKMKLTKK-QCPCLTLEIEVPSTTSHQTRQIVHD 567
+ +I +N +L R+ S + MKLTKK P L +I+ S H + ++ D
Sbjct: 70 -NGEIAFKINCADLNRALKSALEASEVIMKLTKKGNDPFLNFQIQKMSM--HNSVILLQD 126
Query: 568 IPVAVVPWKNWPDFYEPRVPDPDISIELPSLKQL 669
IPV ++ + EP + DP++ I LP LK +
Sbjct: 127 IPVEILTAAQIASYVEPNLADPEVYIYLPPLKSV 160
>UniRef50_Q54NC0 Cluster: Checkpoint clamp complex protein; n=1;
Dictyostelium discoideum AX4|Rep: Checkpoint clamp
complex protein - Dictyostelium discoideum AX4
Length = 271
Score = 64.9 bits (151), Expect = 2e-09
Identities = 50/169 (29%), Positives = 79/169 (46%), Gaps = 1/169 (0%)
Frame = +1
Query: 166 MKFRAVMNNSSPIREFSTIVSTISKLSKECVLRIADDMLYFIV-SDENTGPAPPVLWCEI 342
MKF+A ++ +S + + V I K+ EC+ I D L FI+ SD N G ++CEI
Sbjct: 1 MKFKAKISKASILLK---TVQNIMKIYNECICHITPDKLRFIIQSDFNDGMQ---VFCEI 54
Query: 343 PQSVFFSEYQLVGMDETHQDIYLGLNSGNLARSFVSLKNVKSLKMKLTKKQCPCLTLEIE 522
+S+ F + + + + L L S + V + LTK + + L
Sbjct: 55 QRSLIFENFTIESLSDNEIQFQLDLESLRRVLQSATSNGVSDIFTNLTKVRGGPV-LHFI 113
Query: 523 VPSTTSHQTRQIVHDIPVAVVPWKNWPDFYEPRVPDPDISIELPSLKQL 669
+ S TS I DIP+ ++ + EP +PDP + I LP+LK L
Sbjct: 114 IKSGTSGTV--IFQDIPIVLLTAQQMAQINEPTLPDPLVHILLPNLKNL 160
>UniRef50_Q55LM4 Cluster: Putative uncharacterized protein; n=1;
Filobasidiella neoformans|Rep: Putative uncharacterized
protein - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 335
Score = 63.3 bits (147), Expect = 5e-09
Identities = 47/185 (25%), Positives = 95/185 (51%), Gaps = 17/185 (9%)
Frame = +1
Query: 166 MKFRAVMNNSSPIREFSTIVSTISKLSKECVLRIADDMLYFIVSDENTGPAPPVLWCEIP 345
M+FR ++N + + I+ +++ L++ CV++++++ +YFIV + V W ++
Sbjct: 1 MRFRTGISNVGLLHK---IIRSLAALARSCVIKLSEEQVYFIVPGSESATGVQV-WSQVK 56
Query: 346 QSVFFSEYQLVGMDETHQDIYLGLNSGNLARSFVS-----------LKNVKSLK-----M 477
S F +Y++ ++ +I++ +N +L + S ++N +L +
Sbjct: 57 VSTLFEDYRI--ESNSNNEIWVEVNLDSLVKVLRSADNSVGGINENMRNSAALSQAEVTL 114
Query: 478 KLTKKQ-CPCLTLEIEVPSTTSHQTRQIVHDIPVAVVPWKNWPDFYEPRVPDPDISIELP 654
KL KKQ P +I+ T S ++ I H+I V ++ + D EP P PDI + LP
Sbjct: 115 KLNKKQNQPIWAFDIK-GYTASRKSMIITHEINVKILSSRRQEDLKEPLCPRPDIHVVLP 173
Query: 655 SLKQL 669
+L++L
Sbjct: 174 NLQEL 178
>UniRef50_Q9XYP0 Cluster: Hus1-like protein; n=2;
Caenorhabditis|Rep: Hus1-like protein - Caenorhabditis
elegans
Length = 277
Score = 60.9 bits (141), Expect = 3e-08
Identities = 47/175 (26%), Positives = 85/175 (48%), Gaps = 7/175 (4%)
Frame = +1
Query: 166 MKFRAVMNNSSPIREFSTIVSTISKLSKE-CVLRIADDMLYFIVSDENTGPAPPVLW--C 336
MKF +++ +++ I F I++++SKLSK+ C ++I + L FI +G W
Sbjct: 1 MKFSSLLQDTAAIDVFIKILTSVSKLSKKRCCVKIEKNALNFICC---SGLHDGGSWFSL 57
Query: 337 EIP-QSVFFSEYQLVGMDETHQD---IYLGLNSGNLARSFVSLKNVKSLKMKLTKKQCPC 504
IP S F ++ +VGM+ +++ IY L +L R LK+ ++K P
Sbjct: 58 SIPYSSQIFRKFDMVGMNPRNEEQNLIYFELEIDSLVRVLPGGHCYLKLKLSKSQKDEPM 117
Query: 505 LTLEIEVPSTTSHQTRQIVHDIPVAVVPWKNWPDFYEPRVPDPDISIELPSLKQL 669
L++E+ P + H IP+ ++ K W + P + +SI +P K +
Sbjct: 118 LSVEVRNPEADI-----VSHQIPITIILSKYWNSYSRPSIGHRKMSISMPPPKMM 167
>UniRef50_Q9HEC8 Cluster: Related to mitotic and DNA damage
checkpoint protein hus1; n=1; Neurospora crassa|Rep:
Related to mitotic and DNA damage checkpoint protein
hus1 - Neurospora crassa
Length = 319
Score = 59.7 bits (138), Expect = 6e-08
Identities = 49/169 (28%), Positives = 78/169 (46%), Gaps = 1/169 (0%)
Frame = +1
Query: 166 MKFRAVMNNSSPIREFSTIVSTISKLSKECVLRIADDMLYFIVSDENTGPAPPVLWCEIP 345
M+F+ + N IR FS +V+ ++ L K +R+ DD + F V + TG +W +
Sbjct: 1 MRFKTELRN---IRTFSKLVAALNTLEKIAWVRLDDDTVRFTVIPD-TGSQ---VWASLS 53
Query: 346 QSVFFSEYQLVGMDETHQDIYLGLNSGNLARSFVSLKNVKSLKMKLTKKQ-CPCLTLEIE 522
F Y + +E + I L L G L R+ S N ++LTK+ P L++ I
Sbjct: 54 VDTIFDSYHIQS-NEANNTINLELPLGPLQRALKSALNSNHASLRLTKRDGIPMLSMTIH 112
Query: 523 VPSTTSHQTRQIVHDIPVAVVPWKNWPDFYEPRVPDPDISIELPSLKQL 669
T + H IPV V+ +P+V +PD+ I P L Q+
Sbjct: 113 ---TMTKDAPSAAH-IPVRVLHPDTVETIMQPKVREPDVHIMFPPLLQV 157
>UniRef50_A2EXY8 Cluster: Hus1-like protein; n=1; Trichomonas
vaginalis G3|Rep: Hus1-like protein - Trichomonas
vaginalis G3
Length = 272
Score = 52.4 bits (120), Expect = 1e-05
Identities = 42/153 (27%), Positives = 74/153 (48%)
Frame = +1
Query: 211 FSTIVSTISKLSKECVLRIADDMLYFIVSDENTGPAPPVLWCEIPQSVFFSEYQLVGMDE 390
FS +VS +S E VL + L +VS G LW + FS+YQ+ ++
Sbjct: 12 FSQLVSVLSACGGEVVLHFSKTTLSLVVSQ---GINQIALWIGCSVQLCFSKYQVSSRND 68
Query: 391 THQDIYLGLNSGNLARSFVSLKNVKSLKMKLTKKQCPCLTLEIEVPSTTSHQTRQIVHDI 570
I L NS LA++ +++ ++ M LT+ Q TL+ + S S T+Q++ +
Sbjct: 69 --DIITLKCNSKQLAQA-LTVDAAPTINMSLTR-QGDTNTLQFDHRSNDS--TKQLLQRV 122
Query: 571 PVAVVPWKNWPDFYEPRVPDPDISIELPSLKQL 669
V ++ + D+ EP P +S+ P ++Q+
Sbjct: 123 AVVLLSTRATEDYQEPEWGTPSVSVRFPQIRQV 155
>UniRef50_UPI0000F2CB2B Cluster: PREDICTED: similar to HUS1
checkpoint homolog (S. pombe); n=1; Monodelphis
domestica|Rep: PREDICTED: similar to HUS1 checkpoint
homolog (S. pombe) - Monodelphis domestica
Length = 338
Score = 50.0 bits (114), Expect = 5e-05
Identities = 34/84 (40%), Positives = 46/84 (54%)
Frame = +1
Query: 418 NSGNLARSFVSLKNVKSLKMKLTKKQCPCLTLEIEVPSTTSHQTRQIVHDIPVAVVPWKN 597
N+G L+R+ +N K++K+KLT K PC L +E ++ QIV IPV +P K
Sbjct: 53 NTGKLSRALRMAQNAKTMKIKLTLKY-PCFPLTMEHHFSSYAILTQIVI-IPVGSIPRKL 110
Query: 598 WPDFYEPRVPDPDISIELPSLKQL 669
W EP V D D+S L LK L
Sbjct: 111 WTACEEPTVLDFDVSSYLLLLKTL 134
>UniRef50_P78955 Cluster: Checkpoint protein hus1; n=1;
Schizosaccharomyces pombe|Rep: Checkpoint protein hus1 -
Schizosaccharomyces pombe (Fission yeast)
Length = 287
Score = 44.8 bits (101), Expect = 0.002
Identities = 40/169 (23%), Positives = 72/169 (42%), Gaps = 1/169 (0%)
Frame = +1
Query: 166 MKFRAVMNNSSPIREFSTIVSTISKLSKECVLRIADDMLYFIVSDENTGPAPPVLWCEIP 345
M+F+ ++N + + +V + K+ + C LR+ + + F++ + +W +
Sbjct: 1 MRFKTRISN---LYTLTRLVQALDKIGRFCWLRLMPETVNFVIVPDFRMTQ---VWSVLE 54
Query: 346 QSVFFSEYQLVGMDETHQDIYLGLNSGNLARSFVSLKNVKSLKMKLTKKQC-PCLTLEIE 522
F +Y V I L + N ++ S N ++L+KK P L+L
Sbjct: 55 VETIFEDY--VVQSNADNVINLEVPIDNFYKALRSAANASDSTVRLSKKNNQPLLSLSTT 112
Query: 523 VPSTTSHQTRQIVHDIPVAVVPWKNWPDFYEPRVPDPDISIELPSLKQL 669
S + + + H+IPV V+ EP P+PD I LP L L
Sbjct: 113 W-SGRAFGSNIVTHNIPVRVLSQSYVSVIKEPTAPEPDCHIFLPQLNFL 160
>UniRef50_Q6CUH3 Cluster: Kluyveromyces lactis strain NRRL Y-1140
chromosome C of strain NRRL Y- 1140 of Kluyveromyces
lactis; n=1; Kluyveromyces lactis|Rep: Kluyveromyces
lactis strain NRRL Y-1140 chromosome C of strain NRRL Y-
1140 of Kluyveromyces lactis - Kluyveromyces lactis
(Yeast) (Candida sphaerica)
Length = 386
Score = 40.3 bits (90), Expect = 0.041
Identities = 19/51 (37%), Positives = 26/51 (50%), Gaps = 2/51 (3%)
Frame = +1
Query: 211 FSTIVSTISKLSKECVLRIADDMLYFIVSDENTGPA--PPVLWCEIPQSVF 357
F T + T+SKL K C+LR L I + +TG +WC +P VF
Sbjct: 17 FRTTLITVSKLRKTCILRFTSSRLVIISTPNSTGTVIDQGQVWCTVPHDVF 67
>UniRef50_Q74ZB0 Cluster: DNA damage checkpoint control protein
MEC3; n=1; Eremothecium gossypii|Rep: DNA damage
checkpoint control protein MEC3 - Ashbya gossypii
(Yeast) (Eremothecium gossypii)
Length = 387
Score = 40.3 bits (90), Expect = 0.041
Identities = 25/72 (34%), Positives = 38/72 (52%), Gaps = 8/72 (11%)
Frame = +1
Query: 166 MKFRAVMNNSSP-IREFSTIVSTISKLSKECVLRIADDMLYFIVSDENTGPAPPV----- 327
MK + V+++ S R F T +ST+++L K VLR D L +VS T + +
Sbjct: 1 MKLKLVIDSDSDDYRLFKTTISTVAQLRKTAVLRFTTDRL-IVVSTPKTAASGAILSGDQ 59
Query: 328 --LWCEIPQSVF 357
LWC IP+ +F
Sbjct: 60 GQLWCTIPRDIF 71
>UniRef50_Q92380 Cluster: Meiotic recombination protein rec11; n=2;
Schizosaccharomyces pombe|Rep: Meiotic recombination
protein rec11 - Schizosaccharomyces pombe (Fission
yeast)
Length = 923
Score = 36.3 bits (80), Expect = 0.67
Identities = 21/51 (41%), Positives = 31/51 (60%), Gaps = 1/51 (1%)
Frame = +1
Query: 370 QLVGMDETHQDIYLGLNS-GNLARSFVSLKNVKSLKMKLTKKQCPCLTLEI 519
QL G DET Q++ L LN G A+ V L++V +KL++K C +LE+
Sbjct: 719 QLNGNDET-QNLVLALNKFGCFAKEMVCLRDVNDWNIKLSEKLCEICSLEV 768
>UniRef50_Q8I5V9 Cluster: Putative uncharacterized protein; n=7;
Plasmodium|Rep: Putative uncharacterized protein -
Plasmodium falciparum (isolate 3D7)
Length = 1442
Score = 35.5 bits (78), Expect = 1.2
Identities = 19/67 (28%), Positives = 33/67 (49%)
Frame = +1
Query: 103 NSSSHFARIKQLFSKDEKHITMKFRAVMNNSSPIREFSTIVSTISKLSKECVLRIADDML 282
N+S++ + LFS DE + + + NN + I F + K+SK + I +D
Sbjct: 572 NNSNNTGNSQNLFSDDEHNYNSTY--INNNKNNINSFDELSCNDDKISKSQDIHILNDTY 629
Query: 283 YFIVSDE 303
++ SDE
Sbjct: 630 LYVTSDE 636
>UniRef50_UPI00006CD1B8 Cluster: hypothetical protein
TTHERM_00129420; n=1; Tetrahymena thermophila SB210|Rep:
hypothetical protein TTHERM_00129420 - Tetrahymena
thermophila SB210
Length = 991
Score = 34.3 bits (75), Expect = 2.7
Identities = 16/47 (34%), Positives = 26/47 (55%)
Frame = -1
Query: 436 LRDYPNSILNKCLGEFHPFQPIDIQRKIHFVVFHTIVPEGLVQCFHR 296
+RD N LNK + I+IQR H ++F+ + E +VQ +H+
Sbjct: 766 IRDLLNKYLNKLKQNYVTDNLINIQRTCHVLIFYNKIKEEIVQKYHQ 812
>UniRef50_Q2GXM2 Cluster: Putative uncharacterized protein; n=5;
Pezizomycotina|Rep: Putative uncharacterized protein -
Chaetomium globosum (Soil fungus)
Length = 599
Score = 33.5 bits (73), Expect = 4.7
Identities = 16/38 (42%), Positives = 22/38 (57%)
Frame = +1
Query: 556 IVHDIPVAVVPWKNWPDFYEPRVPDPDISIELPSLKQL 669
I DIPV V+ +P+V +PD+ I+LP L QL
Sbjct: 414 ITQDIPVRVLHPDTVETIMQPKVREPDVHIQLPPLLQL 451
>UniRef50_A1DLN4 Cluster: Cell cycle checkpoint protein (Hus1),
putative; n=8; Pezizomycotina|Rep: Cell cycle checkpoint
protein (Hus1), putative - Neosartorya fischeri (strain
ATCC 1020 / DSM 3700 / NRRL 181)(Aspergillus
fischerianus (strain ATCC 1020 / DSM 3700 / NRRL 181))
Length = 398
Score = 33.5 bits (73), Expect = 4.7
Identities = 17/38 (44%), Positives = 21/38 (55%)
Frame = +1
Query: 556 IVHDIPVAVVPWKNWPDFYEPRVPDPDISIELPSLKQL 669
I +IPV V+ +EPR DPD+ I LPSL L
Sbjct: 154 ITQEIPVKVLHESAVEGLHEPRCRDPDVHIILPSLAHL 191
>UniRef50_UPI000051039E Cluster: COG0477: Permeases of the major
facilitator superfamily; n=1; Brevibacterium linens
BL2|Rep: COG0477: Permeases of the major facilitator
superfamily - Brevibacterium linens BL2
Length = 427
Score = 33.1 bits (72), Expect = 6.2
Identities = 17/46 (36%), Positives = 26/46 (56%)
Frame = -3
Query: 320 GAGPVFSSLTMKYNISSAILRTHSLDSFDIVLTIVENSRIGEELFI 183
G PVF LT KY+ IL H+L + +VL +++ +GE F+
Sbjct: 291 GLSPVFGYLTDKYSAGRVILGGHALFALSLVLGLID--ALGESSFL 334
>UniRef50_A3LW20 Cluster: Predicted protein; n=4;
Saccharomycetales|Rep: Predicted protein - Pichia
stipitis (Yeast)
Length = 325
Score = 32.7 bits (71), Expect = 8.2
Identities = 21/77 (27%), Positives = 38/77 (49%), Gaps = 1/77 (1%)
Frame = +1
Query: 166 MKFRAVMNNSSPIREFSTIVSTISKLSKECVLRIADDMLYFIVSDENTGPAPPVLWCEIP 345
MK + N+ ++ ST+ S ++ L K VLR + LY I + + P +WC +
Sbjct: 1 MKLKLRTQNTETLK--STL-SLVNPLRKFIVLRFCPEKLYIISVNGQSVTQEPQVWCNLK 57
Query: 346 QSVFFSEYQLVGM-DET 393
S F + ++ + D+T
Sbjct: 58 ISSIFDQIEISSLRDDT 74
>UniRef50_Q93SN7 Cluster: Phycoerythrobilin:ferredoxin
oxidoreductase; n=6; Prochlorococcus marinus|Rep:
Phycoerythrobilin:ferredoxin oxidoreductase -
Prochlorococcus marinus subsp. pastoris (strain CCMP
1378 / MED4)
Length = 257
Score = 32.7 bits (71), Expect = 8.2
Identities = 15/44 (34%), Positives = 24/44 (54%)
Frame = -1
Query: 529 TALQFPMLGTDTVSLLTSFLMILHFSRRQKILRDYPNSILNKCL 398
T+ P LG D VSL TS L++L F K+ + + +L + +
Sbjct: 93 TSYNIPFLGVDFVSLPTSHLLVLDFQPSLKVENQFNSELLEQII 136
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 651,505,451
Number of Sequences: 1657284
Number of extensions: 13010333
Number of successful extensions: 31520
Number of sequences better than 10.0: 28
Number of HSP's better than 10.0 without gapping: 30595
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 31488
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 51239674196
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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