Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= bmov11f09
(665 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q9Y020 Cluster: 3-dehydroecdysone 3beta-reductase precu... 274 2e-72
UniRef50_UPI00015B56A2 Cluster: PREDICTED: similar to GA10458-PA... 178 8e-44
UniRef50_UPI00015B56A3 Cluster: PREDICTED: similar to aldo-keto ... 169 7e-41
UniRef50_Q7JVH6 Cluster: LD24696p; n=2; Sophophora|Rep: LD24696p... 163 5e-39
UniRef50_Q7QK25 Cluster: ENSANGP00000019775; n=2; Anopheles gamb... 162 8e-39
UniRef50_Q17DN0 Cluster: Aldo-keto reductase; n=5; Culicidae|Rep... 161 2e-38
UniRef50_Q8VC28 Cluster: Aldo-keto reductase family 1 member C13... 161 2e-38
UniRef50_Q2LZ66 Cluster: GA19341-PA; n=2; Endopterygota|Rep: GA1... 159 7e-38
UniRef50_Q8WRT0 Cluster: 3-dehydrecdysone 3b-reductase; n=1; Tri... 158 1e-37
UniRef50_UPI0000588153 Cluster: PREDICTED: hypothetical protein;... 156 5e-37
UniRef50_Q7PCV3 Cluster: ENSANGP00000031808; n=9; Endopterygota|... 156 5e-37
UniRef50_Q9VTL0 Cluster: CG6083-PA; n=4; Diptera|Rep: CG6083-PA ... 154 2e-36
UniRef50_P45376 Cluster: Aldose reductase; n=21; Bilateria|Rep: ... 152 8e-36
UniRef50_Q9NAI5 Cluster: Putative uncharacterized protein; n=3; ... 151 1e-35
UniRef50_Q41399 Cluster: Chalcone reductase; n=4; eudicotyledons... 149 6e-35
UniRef50_Q8K023 Cluster: Aldo-keto reductase family 1 member C18... 149 6e-35
UniRef50_Q96JD6 Cluster: Aldo-keto reductase family 1 member C-l... 113 4e-34
UniRef50_Q96JD6-2 Cluster: Isoform 2 of Q96JD6 ; n=4; Catarrhini... 113 4e-34
UniRef50_P15121 Cluster: Aldose reductase; n=72; Eumetazoa|Rep: ... 144 1e-33
UniRef50_Q54B70 Cluster: Aldehyde reductase; n=2; Dictyostelium ... 144 2e-33
UniRef50_A5E082 Cluster: GCY protein; n=4; Saccharomycetales|Rep... 144 2e-33
UniRef50_P14550 Cluster: Alcohol dehydrogenase [NADP+]; n=44; Bi... 140 2e-32
UniRef50_Q8CI22 Cluster: 2310005E10Rik protein; n=30; Tetrapoda|... 140 3e-32
UniRef50_Q7PLK6 Cluster: CG40064-PA; n=1; Drosophila melanogaste... 140 3e-32
UniRef50_A3U9Y0 Cluster: Aldehyde reductase; n=5; Bacteroidetes|... 140 4e-32
UniRef50_Q16K66 Cluster: Aldo-keto reductase; n=2; Aedes aegypti... 138 8e-32
UniRef50_Q0VGY1 Cluster: 3-alpha-hydroxysteroid dehydrogenase; n... 138 1e-31
UniRef50_Q96UH3 Cluster: Aldehyde reductase; n=13; Pezizomycotin... 138 1e-31
UniRef50_Q23320 Cluster: Putative uncharacterized protein; n=4; ... 138 1e-31
UniRef50_Q03TW0 Cluster: Aldo/keto reductase of diketogulonate r... 137 2e-31
UniRef50_Q0IBY6 Cluster: Alcohol dehydrogenase; n=2; Chroococcal... 137 3e-31
UniRef50_A3C1Z7 Cluster: Putative uncharacterized protein; n=2; ... 137 3e-31
UniRef50_A2R6Z3 Cluster: Catalytic activity: an alcohol + NADP(+... 137 3e-31
UniRef50_UPI0000498F1F Cluster: oxidoreductase, aldo/keto reduct... 136 4e-31
UniRef50_Q01J82 Cluster: OSIGBa0152K17.5 protein; n=28; Magnolio... 136 4e-31
UniRef50_Q2S340 Cluster: Aldehyde reductase; n=10; Bacteria|Rep:... 136 6e-31
UniRef50_P26690 Cluster: NAD(P)H-dependent 6'-deoxychalcone synt... 135 1e-30
UniRef50_Q6TY50 Cluster: Reductase 2; n=10; Magnoliophyta|Rep: R... 133 4e-30
UniRef50_A5KSS3 Cluster: Aldehyde reductase; n=1; candidate divi... 132 1e-29
UniRef50_Q41E86 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 131 1e-29
UniRef50_Q8SSK6 Cluster: ALDOSE REDUCTASE; n=1; Encephalitozoon ... 131 1e-29
UniRef50_Q2V420 Cluster: Uncharacterized protein At2g37770.1; n=... 131 2e-29
UniRef50_Q0PGJ6 Cluster: Aldo-keto reductase; n=32; Magnoliophyt... 131 2e-29
UniRef50_Q968S3 Cluster: Aldoketoreductase-like protein; n=1; Or... 131 2e-29
UniRef50_Q7G764 Cluster: Probable NAD(P)H-dependent oxidoreducta... 130 3e-29
UniRef50_Q235V6 Cluster: Oxidoreductase, aldo/keto reductase fam... 129 7e-29
UniRef50_Q5BKE9 Cluster: LOC594893 protein; n=5; Xenopus tropica... 128 9e-29
UniRef50_A7CWF9 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: ... 128 9e-29
UniRef50_A4RQH8 Cluster: Predicted protein; n=2; Ostreococcus|Re... 128 1e-28
UniRef50_Q88SL1 Cluster: Oxidoreductase; n=51; Lactobacillales|R... 127 2e-28
UniRef50_Q5FK98 Cluster: Oxidoreductase; n=8; Lactobacillales|Re... 127 2e-28
UniRef50_Q55FL3 Cluster: Aldo-keto reductase; n=2; Dictyostelium... 127 2e-28
UniRef50_Q7ZWA4 Cluster: Zgc:56622; n=6; cellular organisms|Rep:... 127 3e-28
UniRef50_P28475 Cluster: NADP-dependent D-sorbitol-6-phosphate d... 127 3e-28
UniRef50_Q7N0E4 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 126 4e-28
UniRef50_Q9FJK0 Cluster: Aldose reductase-like protein; n=3; cor... 126 4e-28
UniRef50_Q5HR31 Cluster: Oxidoreductase, aldo/keto reductase fam... 126 6e-28
UniRef50_Q6CFG7 Cluster: Yarrowia lipolytica chromosome B of str... 126 6e-28
UniRef50_Q4P4P1 Cluster: Putative uncharacterized protein; n=1; ... 126 6e-28
UniRef50_Q9U2J5 Cluster: Putative uncharacterized protein; n=2; ... 125 8e-28
UniRef50_UPI0000E45E29 Cluster: PREDICTED: similar to aldose red... 125 1e-27
UniRef50_Q6NII7 Cluster: Putative oxidoreductase; n=2; Corynebac... 125 1e-27
UniRef50_Q7ZA52 Cluster: Aldose reductase; n=6; Pezizomycotina|R... 125 1e-27
UniRef50_Q6C2L0 Cluster: Yarrowia lipolytica chromosome F of str... 125 1e-27
UniRef50_P14065 Cluster: Protein GCY; n=13; Saccharomycetales|Re... 125 1e-27
UniRef50_UPI0000E4A7CE Cluster: PREDICTED: similar to LOC553452 ... 124 1e-27
UniRef50_UPI000023D0F1 Cluster: hypothetical protein FG03517.1; ... 124 2e-27
UniRef50_Q1YPE5 Cluster: Aldehyde reductase; n=7; Bacteria|Rep: ... 123 3e-27
UniRef50_A7SIT3 Cluster: Predicted protein; n=1; Nematostella ve... 123 4e-27
UniRef50_A2QBD7 Cluster: Catalytic activity: an alcohol + NADP(+... 123 4e-27
UniRef50_P38115 Cluster: D-arabinose dehydrogenase [NAD(P)+] hea... 123 4e-27
UniRef50_Q1U9L6 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 122 6e-27
UniRef50_Q01HB5 Cluster: OSIGBa0136O08-OSIGBa0153H12.9 protein; ... 122 6e-27
UniRef50_Q2UGR1 Cluster: Aldo/keto reductase family proteins; n=... 122 6e-27
UniRef50_Q1VRG6 Cluster: YvgN; n=1; Psychroflexus torquis ATCC 7... 122 8e-27
UniRef50_P51857 Cluster: 3-oxo-5-beta-steroid 4-dehydrogenase (E... 122 8e-27
UniRef50_A6NPD6 Cluster: Putative uncharacterized protein; n=3; ... 122 1e-26
UniRef50_Q9VHX4 Cluster: CG2767-PA; n=4; Endopterygota|Rep: CG27... 122 1e-26
UniRef50_Q4PDR0 Cluster: Putative uncharacterized protein; n=1; ... 122 1e-26
UniRef50_Q10494 Cluster: Probable oxidoreductase C26F1.07; n=2; ... 122 1e-26
UniRef50_Q9X0A2 Cluster: Oxidoreductase, aldo/keto reductase fam... 121 1e-26
UniRef50_P70883 Cluster: AkrI; n=1; Butyrivibrio fibrisolvens|Re... 121 1e-26
UniRef50_Q7G765 Cluster: Probable NAD(P)H-dependent oxidoreducta... 121 2e-26
UniRef50_Q927E1 Cluster: Lin2848 protein; n=13; Listeria|Rep: Li... 120 3e-26
UniRef50_UPI00006CCCD7 Cluster: oxidoreductase, aldo/keto reduct... 119 5e-26
UniRef50_A3LTU8 Cluster: D-arabinose dehydrogenase; n=5; Sacchar... 119 5e-26
UniRef50_Q838E0 Cluster: Oxidoreductase, aldo/keto reductase fam... 119 7e-26
UniRef50_A2FPE2 Cluster: Oxidoreductase, aldo/keto reductase fam... 119 7e-26
UniRef50_UPI0000519CC2 Cluster: PREDICTED: similar to CG2767-PA;... 118 1e-25
UniRef50_Q4JX70 Cluster: Putative oxidoreductase; n=1; Corynebac... 118 1e-25
UniRef50_Q03PG5 Cluster: Aldo/keto reductase of diketogulonate r... 118 1e-25
UniRef50_Q2U219 Cluster: Aldo/keto reductase family proteins; n=... 118 1e-25
UniRef50_P06632 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 118 1e-25
UniRef50_P22045 Cluster: Probable reductase; n=101; cellular org... 118 2e-25
UniRef50_P27800 Cluster: Aldehyde reductase 1; n=18; root|Rep: A... 118 2e-25
UniRef50_A6ESC0 Cluster: ARA1; n=1; unidentified eubacterium SCB... 117 2e-25
UniRef50_Q5KI95 Cluster: Aldo-keto reductase, putative; n=14; Di... 117 2e-25
UniRef50_UPI00015B5BD7 Cluster: PREDICTED: similar to aldo-keto ... 117 3e-25
UniRef50_Q8F1G4 Cluster: Aldehyde reductase; n=8; Bacteria|Rep: ... 117 3e-25
UniRef50_Q9ZUJ6 Cluster: T2K10.1 protein; n=16; core eudicotyled... 117 3e-25
UniRef50_A6RKL9 Cluster: Putative uncharacterized protein; n=3; ... 117 3e-25
UniRef50_UPI00015B40FA Cluster: PREDICTED: similar to CG2767-PA;... 116 4e-25
UniRef50_Q8ZI40 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 116 4e-25
UniRef50_UPI00006CA3CB Cluster: oxidoreductase, aldo/keto reduct... 116 5e-25
UniRef50_A7BA05 Cluster: Putative uncharacterized protein; n=1; ... 116 5e-25
UniRef50_Q4Q5N9 Cluster: Prostaglandin f synthase, putative; n=7... 116 5e-25
UniRef50_Q22352 Cluster: Putative uncharacterized protein T08H10... 116 5e-25
UniRef50_A1D4E3 Cluster: D-xylose reductase (Xyl1), putative; n=... 116 5e-25
UniRef50_Q03XK0 Cluster: Aldo/keto reductase of diketogulonate r... 115 9e-25
UniRef50_Q17DN1 Cluster: Aldo-keto reductase; n=1; Aedes aegypti... 115 9e-25
UniRef50_UPI00006CD296 Cluster: oxidoreductase, aldo/keto reduct... 115 1e-24
UniRef50_UPI0000499B0E Cluster: oxidoreductase, aldo/keto reduct... 115 1e-24
UniRef50_Q05KR9 Cluster: Benzil reductase; n=5; Bacillales|Rep: ... 115 1e-24
UniRef50_UPI00015B4B22 Cluster: PREDICTED: similar to GA15457-PA... 114 2e-24
UniRef50_Q7NB44 Cluster: ARA1; n=3; Firmicutes|Rep: ARA1 - Mycop... 114 2e-24
UniRef50_A7P424 Cluster: Chromosome chr1 scaffold_5, whole genom... 114 2e-24
UniRef50_A2EHN6 Cluster: Oxidoreductase, aldo/keto reductase fam... 114 2e-24
UniRef50_A6W8E7 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 113 3e-24
UniRef50_Q7PM68 Cluster: ENSANGP00000014386; n=1; Anopheles gamb... 113 3e-24
UniRef50_P15339 Cluster: 2,5-diketo-D-gluconic acid reductase B;... 113 3e-24
UniRef50_Q568D7 Cluster: Zgc:110366; n=7; Euteleostomi|Rep: Zgc:... 113 4e-24
UniRef50_Q5FK99 Cluster: Oxidoreductase aldo-keto reductase fami... 113 4e-24
UniRef50_UPI000065D0BD Cluster: Homolog of Homo sapiens "AKR1B1 ... 113 5e-24
UniRef50_Q7WSY4 Cluster: Putative aldo-keto reductase; n=1; Prop... 113 5e-24
UniRef50_Q9HGY0 Cluster: Glycerol dehydrogenase; n=8; Saccharomy... 113 5e-24
UniRef50_P38715 Cluster: NADPH-dependent aldose reductase GRE3; ... 113 5e-24
UniRef50_Q9ZBW7 Cluster: Putative oxidoreductase; n=2; Actinomyc... 112 6e-24
UniRef50_A7ALH6 Cluster: Putative uncharacterized protein; n=1; ... 112 8e-24
UniRef50_Q6CEJ0 Cluster: Yarrowia lipolytica chromosome B of str... 112 8e-24
UniRef50_A6LZ55 Cluster: 2,5-didehydrogluconate reductase; n=1; ... 111 1e-23
UniRef50_Q1IN88 Cluster: Aldehyde reductase; n=5; Bacteria|Rep: ... 111 1e-23
UniRef50_A3JU52 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 111 1e-23
UniRef50_P23901 Cluster: Aldose reductase; n=9; Poaceae|Rep: Ald... 111 1e-23
UniRef50_Q8EUH6 Cluster: Oxidoreductase; n=1; Mycoplasma penetra... 111 2e-23
UniRef50_Q83N50 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 111 2e-23
UniRef50_Q4PAT5 Cluster: Putative uncharacterized protein; n=1; ... 111 2e-23
UniRef50_Q6F7K7 Cluster: 2,5-diketo-D-gluconate reductase; n=20;... 110 3e-23
UniRef50_Q6RZX1 Cluster: Gld1; n=22; Pezizomycotina|Rep: Gld1 - ... 110 3e-23
UniRef50_P47137 Cluster: Probable oxidoreductase YJR096W; n=8; S... 110 3e-23
UniRef50_UPI0000D9A956 Cluster: PREDICTED: similar to aldo-keto ... 110 3e-23
UniRef50_Q9X265 Cluster: Oxidoreductase, aldo/keto reductase fam... 110 3e-23
UniRef50_Q7VG53 Cluster: Aldo-keto reductase; n=28; Bacteria|Rep... 110 3e-23
UniRef50_Q17G72 Cluster: Aldo-keto reductase; n=9; Endopterygota... 110 3e-23
UniRef50_O13848 Cluster: NADH/NADPH dependent indole-3-acetaldeh... 109 6e-23
UniRef50_Q5FLI5 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: ... 109 8e-23
UniRef50_Q043M4 Cluster: Aldo/keto reductase of diketogulonate r... 109 8e-23
UniRef50_Q24C22 Cluster: Oxidoreductase, aldo/keto reductase fam... 109 8e-23
UniRef50_Q5XJM7 Cluster: Zgc:101765; n=5; Eumetazoa|Rep: Zgc:101... 108 1e-22
UniRef50_Q1RFP0 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 108 1e-22
UniRef50_A7PNI3 Cluster: Chromosome chr1 scaffold_22, whole geno... 108 1e-22
UniRef50_Q5T2L2 Cluster: Aldo-keto reductase family 1 member C-l... 107 2e-22
UniRef50_Q0CLQ2 Cluster: Putative uncharacterized protein; n=1; ... 107 2e-22
UniRef50_A2QVE5 Cluster: Similarity: shows similarity to several... 107 2e-22
UniRef50_Q03X85 Cluster: Aldo/keto reductase of diketogulonate r... 107 3e-22
UniRef50_Q5FKI1 Cluster: Reductase-dehydrogenase; n=1; Lactobaci... 106 4e-22
UniRef50_Q8J0K1 Cluster: 4-dihydromethyltrisporate dehydrogenase... 106 4e-22
UniRef50_Q5BLA6 Cluster: Zgc:110782; n=2; Danio rerio|Rep: Zgc:1... 106 5e-22
UniRef50_A0JRJ3 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 105 1e-21
UniRef50_A2EYY6 Cluster: Oxidoreductase, aldo/keto reductase fam... 105 1e-21
UniRef50_A2QL02 Cluster: Putative frameshift; n=1; Aspergillus n... 105 1e-21
UniRef50_Q5K8C5 Cluster: Aldo-keto reductase, putative; n=1; Fil... 105 1e-21
UniRef50_Q88TV9 Cluster: Oxidoreductase; n=4; Lactobacillus|Rep:... 104 2e-21
UniRef50_A5VK30 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 104 2e-21
UniRef50_Q68ST9 Cluster: Reductase AKOR2; n=2; Pleurotus djamor|... 104 2e-21
UniRef50_A1UEC5 Cluster: 2,5-didehydrogluconate reductase; n=20;... 104 2e-21
UniRef50_Q89JN4 Cluster: Oxidoreductase; n=8; Rhizobiales|Rep: O... 103 4e-21
UniRef50_Q8ET73 Cluster: 2,5-diketo-D-gluconate reductase; n=12;... 103 5e-21
UniRef50_Q0CK00 Cluster: Predicted protein; n=1; Aspergillus ter... 103 5e-21
UniRef50_A7CUW0 Cluster: 2,5-didehydrogluconate reductase; n=6; ... 102 7e-21
UniRef50_UPI00015B4912 Cluster: PREDICTED: similar to aldo-keto ... 102 9e-21
UniRef50_Q02198 Cluster: Morphine 6-dehydrogenase; n=5; Bacteria... 102 9e-21
UniRef50_Q9A2X8 Cluster: Oxidoreductase, aldo/keto reductase fam... 101 1e-20
UniRef50_A0JX62 Cluster: 2,5-didehydrogluconate reductase; n=9; ... 101 1e-20
UniRef50_A5ZYE6 Cluster: Putative uncharacterized protein; n=1; ... 101 2e-20
UniRef50_A5PDA8 Cluster: Putative oxidoreductase protein; n=1; E... 101 2e-20
UniRef50_A3UJS6 Cluster: Oxidoreductase; n=3; Alphaproteobacteri... 101 2e-20
UniRef50_Q76L37 Cluster: Conjugated polyketone reductase C1; n=3... 101 2e-20
UniRef50_A0JRJ6 Cluster: Aldo/keto reductase; n=2; Micrococcinea... 100 4e-20
UniRef50_UPI0000DB6EE9 Cluster: PREDICTED: similar to C35D10.6; ... 99 5e-20
UniRef50_Q28P63 Cluster: Aldo/keto reductase; n=4; Rhodobacterac... 99 5e-20
UniRef50_A7RRF6 Cluster: Predicted protein; n=2; Nematostella ve... 99 5e-20
UniRef50_Q5FT75 Cluster: Putative 2,5-diketo-D-gluconic acid red... 100 6e-20
UniRef50_A3VRL4 Cluster: Putative uncharacterized protein; n=1; ... 100 6e-20
UniRef50_Q17568 Cluster: Putative uncharacterized protein; n=1; ... 99 8e-20
UniRef50_A6RMS0 Cluster: Putative uncharacterized protein; n=1; ... 99 8e-20
UniRef50_Q8G7K9 Cluster: Dehydrogenase or reductase protein; n=4... 99 1e-19
UniRef50_Q4V008 Cluster: Oxidoreductase; n=4; Proteobacteria|Rep... 99 1e-19
UniRef50_Q5TNP1 Cluster: ENSANGP00000029046; n=2; Culicidae|Rep:... 99 1e-19
UniRef50_Q5UX52 Cluster: Oxidoreductase aldo/keto reductase fami... 99 1e-19
UniRef50_Q6U5V3 Cluster: Putative uncharacterized protein; n=1; ... 98 1e-19
UniRef50_Q7QVQ9 Cluster: GLP_302_44328_45269; n=1; Giardia lambl... 98 1e-19
UniRef50_A6VNW9 Cluster: Aldo/keto reductase precursor; n=1; Act... 98 2e-19
UniRef50_Q929C8 Cluster: Lin2349 protein; n=12; Listeria|Rep: Li... 97 3e-19
UniRef50_Q7VHE1 Cluster: Putative uncharacterized protein; n=1; ... 97 3e-19
UniRef50_Q03U37 Cluster: Aldo/keto reductase of diketogulonate r... 97 3e-19
UniRef50_Q927P9 Cluster: Lin2739 protein; n=12; Bacteria|Rep: Li... 96 6e-19
UniRef50_Q890A0 Cluster: Oxidoreductase; n=6; Lactobacillales|Re... 96 6e-19
UniRef50_Q54NR2 Cluster: Aldo-keto reductase; n=3; Dictyostelium... 96 6e-19
UniRef50_P91997 Cluster: Putative uncharacterized protein; n=4; ... 96 6e-19
UniRef50_A3VHZ9 Cluster: Oxidoreductase; n=1; Rhodobacterales ba... 96 8e-19
UniRef50_A5BF24 Cluster: Putative uncharacterized protein; n=1; ... 95 1e-18
UniRef50_A5DRJ6 Cluster: Putative uncharacterized protein; n=4; ... 95 1e-18
UniRef50_A0AWM8 Cluster: Aldo/keto reductase; n=4; Actinomycetal... 95 1e-18
UniRef50_Q572D2 Cluster: Aldo-keto reductase, putative; n=1; Phy... 95 1e-18
UniRef50_A7BES9 Cluster: Putative uncharacterized protein; n=1; ... 95 2e-18
UniRef50_Q15NA5 Cluster: Aldo/keto reductase; n=2; Gammaproteoba... 94 2e-18
UniRef50_Q9P6D3 Cluster: Related to aldo-keto reductase YPR1; n=... 94 2e-18
UniRef50_Q11BF8 Cluster: Aldo/keto reductase; n=12; Bacteria|Rep... 94 3e-18
UniRef50_UPI0000D56CE5 Cluster: PREDICTED: similar to CG6084-PA,... 93 4e-18
UniRef50_Q9HM42 Cluster: Alcohol dehydrogenase related protein; ... 93 4e-18
UniRef50_Q8Y463 Cluster: Lmo2592 protein; n=40; Bacteria|Rep: Lm... 93 5e-18
UniRef50_A6PR52 Cluster: Aldo/keto reductase; n=1; Victivallis v... 93 5e-18
UniRef50_A0L1A2 Cluster: Aldo/keto reductase; n=8; Gammaproteoba... 93 7e-18
UniRef50_A6WDZ5 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:... 92 1e-17
UniRef50_Q7R2T6 Cluster: GLP_291_56367_57278; n=1; Giardia lambl... 92 1e-17
UniRef50_Q6WGK4 Cluster: Aldose reductase; n=1; Pristionchus pac... 92 1e-17
UniRef50_Q18483 Cluster: Putative uncharacterized protein; n=2; ... 92 1e-17
UniRef50_O14088 Cluster: Xylose and arabinose reductase; n=1; Sc... 92 1e-17
UniRef50_Q4FY75 Cluster: Aldo-keto reductase-like protein; n=5; ... 92 1e-17
UniRef50_A2UAH0 Cluster: Aldo/keto reductase; n=1; Bacillus coag... 91 2e-17
UniRef50_Q21274 Cluster: Putative uncharacterized protein; n=1; ... 91 2e-17
UniRef50_Q8ZH36 Cluster: 2,5-diketo-D-gluconic acid reductase B;... 91 2e-17
UniRef50_Q0SFM4 Cluster: Probable 2,5-didehydrogluconate reducta... 91 2e-17
UniRef50_Q76L36 Cluster: Conjugated polyketone reductase C2; n=1... 91 2e-17
UniRef50_A7TLC4 Cluster: Putative uncharacterized protein; n=1; ... 91 3e-17
UniRef50_Q3E9M9 Cluster: Uncharacterized protein At5g01670.2; n=... 90 4e-17
UniRef50_Q8EVS8 Cluster: Oxidoreductase; n=1; Mycoplasma penetra... 90 5e-17
UniRef50_Q2BBN7 Cluster: YvgN; n=1; Bacillus sp. NRRL B-14911|Re... 90 5e-17
UniRef50_A4YQ04 Cluster: 2,5-diketo-D-gluconate reductase B; n=1... 90 5e-17
UniRef50_Q2H7A8 Cluster: Putative uncharacterized protein; n=1; ... 90 5e-17
UniRef50_A7SGW6 Cluster: Predicted protein; n=1; Nematostella ve... 89 7e-17
UniRef50_Q8EVT8 Cluster: Oxidoreductase-aldo/keto reductase fami... 89 1e-16
UniRef50_Q11DV1 Cluster: Aldo/keto reductase; n=10; Alphaproteob... 89 1e-16
UniRef50_A2QB88 Cluster: Contig An01c0460, complete genome. prec... 89 1e-16
UniRef50_A7D6Q0 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 89 1e-16
UniRef50_Q14LU6 Cluster: Putative aldo/keto reductase oxidoreduc... 88 2e-16
UniRef50_Q7XY49 Cluster: Mannose 6-phosphate reductase; n=1; Gri... 88 2e-16
UniRef50_A3WP89 Cluster: Aldo/keto reductase; n=1; Idiomarina ba... 88 2e-16
UniRef50_Q4PHK0 Cluster: Putative uncharacterized protein; n=1; ... 88 2e-16
UniRef50_Q07551 Cluster: NADPH-dependent alpha-keto amide reduct... 87 4e-16
UniRef50_A2RMU6 Cluster: Oxidoreductase, aldo/keto reductase fam... 87 5e-16
UniRef50_UPI000155CAC7 Cluster: PREDICTED: hypothetical protein;... 86 6e-16
UniRef50_Q3CZS2 Cluster: Oxidoreductase, aldo/keto reductase fam... 86 6e-16
UniRef50_A4FEB9 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 86 6e-16
UniRef50_Q5V663 Cluster: Aldehyde reductase; n=6; Halobacteriace... 86 8e-16
UniRef50_Q16CS5 Cluster: 2,5-diketo-D-gluconic acid reductase B,... 85 1e-15
UniRef50_Q68A33 Cluster: Aldo-keto reductase 1a; n=1; Ciona inte... 85 1e-15
UniRef50_Q5KKZ8 Cluster: Aldo-keto reductase, putative; n=2; Fil... 85 1e-15
UniRef50_A3LWP0 Cluster: Aldo/keto reductase; n=7; Saccharomycet... 85 1e-15
UniRef50_Q75E75 Cluster: ABL209Cp; n=1; Eremothecium gossypii|Re... 85 1e-15
UniRef50_Q4P1G1 Cluster: Putative uncharacterized protein; n=1; ... 85 1e-15
UniRef50_Q59Z55 Cluster: Potential aldo/keto reductase; n=6; Sac... 85 2e-15
UniRef50_Q5NLW3 Cluster: Putative oxidoreductase; n=1; Zymomonas... 84 3e-15
UniRef50_A3T261 Cluster: Putative uncharacterized protein; n=1; ... 84 3e-15
UniRef50_Q5KD52 Cluster: Oxidoreductase, putative; n=1; Filobasi... 84 3e-15
UniRef50_Q9C1X5 Cluster: Xylose and arabinose reductase; n=1; Sc... 83 6e-15
UniRef50_Q00XM4 Cluster: Aldo/keto reductase family proteins; n=... 83 8e-15
UniRef50_Q4PE96 Cluster: Putative uncharacterized protein; n=1; ... 82 1e-14
UniRef50_Q979I4 Cluster: Aldo / keto reductase; n=3; Archaea|Rep... 82 1e-14
UniRef50_Q5V6N9 Cluster: Alcohol dehydrogenase; n=2; Halobacteri... 82 1e-14
UniRef50_Q09632 Cluster: Probable oxidoreductase ZK1290.5; n=2; ... 82 1e-14
UniRef50_UPI000023DF27 Cluster: hypothetical protein FG07276.1; ... 82 1e-14
UniRef50_A7EW94 Cluster: Putative uncharacterized protein; n=1; ... 82 1e-14
UniRef50_Q97U17 Cluster: Oxidoreductase, aldo/keto reductase fam... 82 1e-14
UniRef50_Q5V1M9 Cluster: Oxidoreductase aldo/keto reductase fami... 82 1e-14
UniRef50_Q1Q8W8 Cluster: Aldo/keto reductase; n=1; Psychrobacter... 81 2e-14
UniRef50_Q14LA8 Cluster: Putative aldo/keto reductase oxidoreduc... 81 2e-14
UniRef50_Q5V398 Cluster: Oxidoreductase aldo/keto reductase fami... 81 2e-14
UniRef50_Q2CAL9 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 81 3e-14
UniRef50_A7D761 Cluster: Aldo/keto reductase; n=2; Halobacteriac... 81 3e-14
UniRef50_A1RB46 Cluster: 2,5-diketo-D-gluconate reductase; n=1; ... 80 5e-14
UniRef50_Q5B5R6 Cluster: Putative uncharacterized protein; n=1; ... 80 5e-14
UniRef50_Q9P734 Cluster: Related to 2, 5-diketo-D-gluconic acid ... 79 1e-13
UniRef50_Q8ZU65 Cluster: Aldo-keto reductase, putative; n=4; The... 79 1e-13
UniRef50_Q4JCC1 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 79 1e-13
UniRef50_UPI000038E317 Cluster: hypothetical protein Faci_030017... 79 1e-13
UniRef50_Q61U89 Cluster: Putative uncharacterized protein CBG054... 79 1e-13
UniRef50_Q5UYI9 Cluster: Oxidoreductase; n=1; Haloarcula marismo... 79 1e-13
UniRef50_A3H9Y8 Cluster: Aldo/keto reductase; n=2; Caldivirga ma... 78 2e-13
UniRef50_Q4WP69 Cluster: Aldehyde reductase, putative; n=1; Aspe... 78 2e-13
UniRef50_Q4WUF7 Cluster: Aldo-keto reductase, putative; n=3; Pez... 77 3e-13
UniRef50_Q4WI64 Cluster: Aldehyde reductase, putative; n=22; Pez... 77 4e-13
UniRef50_Q1DLF1 Cluster: Putative uncharacterized protein; n=1; ... 77 4e-13
UniRef50_A1CAM7 Cluster: Aldo-keto reductase, putative; n=9; Dik... 77 4e-13
UniRef50_Q6CWB9 Cluster: Similarities with sp|Q12458 Saccharomyc... 76 7e-13
UniRef50_Q4Q973 Cluster: Aldo/keto reductase, putative; n=3; Lei... 76 9e-13
UniRef50_Q5KCN9 Cluster: Putative uncharacterized protein; n=1; ... 76 9e-13
UniRef50_A7RUA2 Cluster: Predicted protein; n=1; Nematostella ve... 75 1e-12
UniRef50_A5AD50 Cluster: Putative uncharacterized protein; n=3; ... 75 2e-12
UniRef50_Q1M4Z6 Cluster: Putative aldo-keto reductase/oxidase; n... 75 2e-12
UniRef50_Q4DJ59 Cluster: Aldo/keto reductase, putative; n=2; Try... 74 4e-12
UniRef50_Q9V2P1 Cluster: Myo-inositol degradation; n=5; Archaea|... 74 4e-12
UniRef50_Q59ZT1 Cluster: Putative uncharacterized protein; n=1; ... 73 5e-12
UniRef50_Q6L139 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 73 5e-12
UniRef50_Q5ZTU6 Cluster: D-xylose reductase III; n=5; Legionella... 71 2e-11
UniRef50_Q8DK16 Cluster: Tlr1054 protein; n=6; Cyanobacteria|Rep... 71 3e-11
UniRef50_A0LJ47 Cluster: Aldo/keto reductase; n=1; Syntrophobact... 71 3e-11
UniRef50_A7D6I8 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 71 3e-11
UniRef50_Q5B034 Cluster: Putative uncharacterized protein; n=1; ... 70 4e-11
UniRef50_Q0GU15 Cluster: ORF28; n=3; Bacteria|Rep: ORF28 - Lacto... 70 6e-11
UniRef50_A6SI80 Cluster: Putative uncharacterized protein; n=1; ... 70 6e-11
UniRef50_A7D7K7 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 70 6e-11
UniRef50_A1S0T5 Cluster: Aldo/keto reductase; n=2; Thermoprotei|... 70 6e-11
UniRef50_Q64UK5 Cluster: Aldo/keto reductase family oxidoreducta... 69 8e-11
UniRef50_Q11B35 Cluster: Aldo/keto reductase; n=1; Mesorhizobium... 69 8e-11
UniRef50_Q5KKC5 Cluster: Putative uncharacterized protein; n=2; ... 69 8e-11
UniRef50_A5BYJ4 Cluster: Putative uncharacterized protein; n=1; ... 69 1e-10
UniRef50_Q97V56 Cluster: Dehydrogenase; n=8; Thermoprotei|Rep: D... 69 1e-10
UniRef50_Q97UV9 Cluster: Oxidoreductase; n=1; Sulfolobus solfata... 69 1e-10
UniRef50_Q1PV10 Cluster: Putative uncharacterized protein; n=1; ... 69 1e-10
UniRef50_P91021 Cluster: Putative uncharacterized protein; n=1; ... 68 2e-10
UniRef50_Q03BE0 Cluster: Aldo/keto reductase family enzyme; n=5;... 68 2e-10
UniRef50_A6BIJ0 Cluster: Putative uncharacterized protein; n=1; ... 68 2e-10
UniRef50_Q9USV2 Cluster: Xylose and arabinose reductase; n=2; Sc... 68 2e-10
UniRef50_A6QXT4 Cluster: Predicted protein; n=1; Ajellomyces cap... 68 2e-10
UniRef50_P80874 Cluster: General stress protein 69; n=16; cellul... 68 2e-10
UniRef50_A4M6J9 Cluster: Aldo/keto reductase; n=1; Petrotoga mob... 67 4e-10
UniRef50_A6QVW8 Cluster: Predicted protein; n=1; Ajellomyces cap... 66 5e-10
UniRef50_Q6CGE9 Cluster: Similar to sp|P47137 Saccharomyces cere... 66 7e-10
UniRef50_A3DNU7 Cluster: Aldo/keto reductase; n=3; Desulfurococc... 66 7e-10
UniRef50_Q8EUX1 Cluster: Aldo/keto reductase family oxidoreducta... 65 2e-09
UniRef50_Q7NK63 Cluster: Gll1617 protein; n=1; Gloeobacter viola... 65 2e-09
UniRef50_A7LSN6 Cluster: Putative uncharacterized protein; n=3; ... 65 2e-09
UniRef50_A1DD54 Cluster: Aldo/keto reductase; n=3; Trichocomacea... 64 2e-09
UniRef50_Q8UIN0 Cluster: Oxidoreductase; n=3; Alphaproteobacteri... 64 4e-09
UniRef50_Q8EVP7 Cluster: Putative oxidoreductase; n=3; Bacteria|... 64 4e-09
UniRef50_A0QWF1 Cluster: Aldo/keto reductase; n=1; Mycobacterium... 64 4e-09
UniRef50_Q013C5 Cluster: Glycerol dehydrogenase, putative; n=2; ... 63 5e-09
UniRef50_Q391C9 Cluster: Aldo/keto reductase; n=10; Proteobacter... 63 7e-09
UniRef50_A2G4I3 Cluster: Oxidoreductase, aldo/keto reductase fam... 62 9e-09
UniRef50_P82125 Cluster: 1,5-anhydro-D-fructose reductase; n=1; ... 62 9e-09
UniRef50_A4IJ00 Cluster: LOC548351 protein; n=1; Xenopus tropica... 60 1e-08
UniRef50_A6X3I0 Cluster: Aldo/keto reductase; n=3; Bacteria|Rep:... 62 2e-08
UniRef50_A6SUJ2 Cluster: Uncharacterized conserved protein; n=2;... 62 2e-08
UniRef50_A2UBC7 Cluster: Aldo/keto reductase; n=3; cellular orga... 62 2e-08
UniRef50_Q5KYH6 Cluster: K+ channel beta subunit; n=5; Bacteria|... 61 2e-08
UniRef50_Q5FHT2 Cluster: Aldehyde reductase; n=4; Lactobacillus|... 61 2e-08
UniRef50_Q2FGN2 Cluster: Oxidoreductase, aldo/keto reductase fam... 60 4e-08
UniRef50_A0K203 Cluster: Aldo/keto reductase; n=2; Arthrobacter|... 60 4e-08
UniRef50_Q18903 Cluster: Putative uncharacterized protein C56G3.... 60 4e-08
UniRef50_Q8Y5Q1 Cluster: Lmo2005 protein; n=34; cellular organis... 60 5e-08
UniRef50_Q4Q5X1 Cluster: Aldehyde reductase, putative; n=75; cel... 60 5e-08
UniRef50_A4R217 Cluster: Putative uncharacterized protein; n=1; ... 60 5e-08
UniRef50_P77735 Cluster: Uncharacterized oxidoreductase yajO; n=... 60 5e-08
UniRef50_Q94A68 Cluster: Uncharacterized oxidoreductase At1g0669... 60 5e-08
UniRef50_Q2J7H2 Cluster: Aldo/keto reductase; n=16; Bacteria|Rep... 60 6e-08
UniRef50_Q89RG2 Cluster: Aldo/keto reductase; n=11; Bacteria|Rep... 59 8e-08
UniRef50_Q81RN9 Cluster: Oxidoreductase, aldo/keto reductase fam... 59 8e-08
UniRef50_Q67NQ1 Cluster: Oxidoreductase; n=1; Symbiobacterium th... 59 8e-08
UniRef50_Q97UG6 Cluster: Oxidoreductase; n=5; Archaea|Rep: Oxido... 59 8e-08
UniRef50_UPI00015BB020 Cluster: aldo/keto reductase; n=1; Ignico... 59 1e-07
UniRef50_UPI00005F9591 Cluster: COG0656: Aldo/keto reductases, r... 59 1e-07
UniRef50_Q660Z5 Cluster: Aldose reductase, putative; n=3; Borrel... 59 1e-07
UniRef50_Q64W37 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 59 1e-07
UniRef50_Q1FGT0 Cluster: Aldo/keto reductase; n=1; Clostridium p... 59 1e-07
UniRef50_A6WAE5 Cluster: Aldo/keto reductase; n=1; Kineococcus r... 59 1e-07
UniRef50_Q8YXI8 Cluster: All1225 protein; n=9; Cyanobacteria|Rep... 58 1e-07
UniRef50_Q3I1P2 Cluster: Aldo-keto oxidoreductase; n=6; Bacteria... 58 1e-07
UniRef50_A1SCW7 Cluster: Aldo/keto reductase; n=2; Actinomycetal... 58 1e-07
UniRef50_Q1EZH4 Cluster: Aldo/keto reductase:4Fe-4S ferredoxin, ... 58 2e-07
UniRef50_Q6NKP1 Cluster: At5g53580; n=18; cellular organisms|Rep... 58 2e-07
UniRef50_Q7VG62 Cluster: Aldo-keto reductase; n=2; Helicobacter|... 58 3e-07
UniRef50_Q1U6R9 Cluster: Aldo/keto reductase; n=25; Bacilli|Rep:... 58 3e-07
UniRef50_Q55ML8 Cluster: Putative uncharacterized protein; n=2; ... 58 3e-07
UniRef50_P46905 Cluster: Uncharacterized oxidoreductase yccK; n=... 58 3e-07
UniRef50_UPI0000DAE567 Cluster: hypothetical protein Rgryl_01000... 57 3e-07
UniRef50_Q21EY6 Cluster: Aldo/keto reductase; n=1; Saccharophagu... 57 3e-07
UniRef50_Q0LKQ4 Cluster: Aldo/keto reductase; n=1; Herpetosiphon... 57 3e-07
UniRef50_A5CYR4 Cluster: Predicted oxidoreductases; n=2; Clostri... 57 3e-07
UniRef50_Q034L5 Cluster: Aryl-alcohol dehydrogenase related enzy... 57 4e-07
UniRef50_Q1IQ78 Cluster: Aldo/keto reductase; n=1; Acidobacteria... 56 6e-07
UniRef50_Q03I00 Cluster: Aryl-alcohol dehydrogenase related enzy... 56 6e-07
UniRef50_A6LWU9 Cluster: Aldo/keto reductase; n=3; Clostridium|R... 56 6e-07
UniRef50_Q4HND9 Cluster: Oxidoreductase, aldo/keto reductase fam... 44 6e-07
UniRef50_Q8PN61 Cluster: Oxidoreductase; n=5; Proteobacteria|Rep... 56 8e-07
UniRef50_Q0RGM0 Cluster: Putative aldoketoreductase; n=2; Franki... 56 8e-07
UniRef50_Q7M4N1 Cluster: Dihydrodiol dehydrogenase DD2; n=2; Hom... 56 8e-07
UniRef50_Q6CI80 Cluster: Similar to tr|O59826 Schizosaccharomyce... 56 8e-07
UniRef50_Q55493 Cluster: Auxin-induced protein; n=2; Bacteria|Re... 56 1e-06
UniRef50_P76234 Cluster: Uncharacterized protein yeaE; n=39; Bac... 56 1e-06
UniRef50_A6W292 Cluster: Aldo/keto reductase; n=9; Bacteria|Rep:... 55 1e-06
UniRef50_A0Y7Y8 Cluster: Aldo/keto reductase; n=1; marine gamma ... 55 1e-06
UniRef50_UPI0001556575 Cluster: PREDICTED: similar to Aldo-keto ... 55 2e-06
UniRef50_Q88TP1 Cluster: Oxidoreductase; n=3; Bacteria|Rep: Oxid... 55 2e-06
UniRef50_A6CMV7 Cluster: Putative uncharacterized protein; n=2; ... 55 2e-06
UniRef50_Q3WFK9 Cluster: Aldo/keto reductase precursor; n=1; Fra... 54 2e-06
UniRef50_A7HEV1 Cluster: Aldo/keto reductase; n=13; Bacteria|Rep... 54 2e-06
UniRef50_A7BLU0 Cluster: Aldo/keto reductase family; n=1; Beggia... 54 2e-06
UniRef50_A1ZPI5 Cluster: Oxidoreductase; n=1; Microscilla marina... 54 2e-06
UniRef50_Q04TM6 Cluster: Aryl-alcohol dehydrogenase-related oxid... 54 3e-06
UniRef50_A3H9H5 Cluster: Aldo/keto reductase; n=2; Archaea|Rep: ... 54 3e-06
UniRef50_A3H7G3 Cluster: Aldo/keto reductase; n=2; Caldivirga ma... 54 3e-06
UniRef50_UPI00005A2CCB Cluster: PREDICTED: similar to Aldose red... 54 4e-06
UniRef50_Q837G5 Cluster: Oxidoreductase, aldo/keto reductase 2 f... 54 4e-06
UniRef50_A0JVH3 Cluster: Aldo/keto reductase; n=17; Bacteria|Rep... 54 4e-06
UniRef50_Q89JX0 Cluster: Oxidoreductase; n=26; Bacteria|Rep: Oxi... 53 5e-06
UniRef50_Q6XUT6 Cluster: Oxido-reductase/dehydratase; n=3; Bacte... 53 5e-06
UniRef50_A7AFQ7 Cluster: Putative uncharacterized protein; n=1; ... 53 5e-06
UniRef50_A4XIJ0 Cluster: Aldo/keto reductase; n=1; Caldicellulos... 53 5e-06
UniRef50_Q23TY7 Cluster: Oxidoreductase, aldo/keto reductase fam... 53 5e-06
UniRef50_Q31SB1 Cluster: Putative uncharacterized protein; n=2; ... 53 7e-06
UniRef50_A6SJ74 Cluster: Putative uncharacterized protein; n=1; ... 53 7e-06
UniRef50_Q46851 Cluster: Uncharacterized protein yghZ; n=126; Ba... 53 7e-06
UniRef50_A6FYX9 Cluster: Oxidoreductase; n=1; Plesiocystis pacif... 52 9e-06
UniRef50_Q97UJ7 Cluster: Oxidoreductase; n=4; Archaea|Rep: Oxido... 52 9e-06
UniRef50_A0RWV1 Cluster: Oxidoreductase; n=4; Thermoprotei|Rep: ... 52 9e-06
UniRef50_Q8YAN3 Cluster: Lmo0084 protein; n=11; Listeria monocyt... 52 1e-05
UniRef50_Q38Z15 Cluster: Putative aldo/keto reductase; n=2; Bact... 52 1e-05
UniRef50_Q7D3N9 Cluster: AGR_pAT_274p; n=3; Proteobacteria|Rep: ... 52 1e-05
UniRef50_Q87SA8 Cluster: Oxidoreductase Tas, aldo/keto reductase... 52 2e-05
UniRef50_Q93KW0 Cluster: Putative oxidoreductase; n=1; Streptomy... 52 2e-05
UniRef50_Q7S6W9 Cluster: Putative uncharacterized protein NCU055... 52 2e-05
UniRef50_UPI0000D9C1BD Cluster: PREDICTED: similar to aldo-keto ... 51 2e-05
UniRef50_Q7NCE7 Cluster: Glr3032 protein; n=5; Cyanobacteria|Rep... 51 2e-05
UniRef50_Q701X7 Cluster: Putative uncharacterized protein; n=1; ... 51 2e-05
UniRef50_UPI00003C85A8 Cluster: hypothetical protein Faci_030001... 51 3e-05
UniRef50_Q98EU0 Cluster: Oxidoreductase; MocA; n=27; Bacteria|Re... 51 3e-05
UniRef50_Q2J8X9 Cluster: Aldo/keto reductase; n=3; Frankia|Rep: ... 51 3e-05
UniRef50_A1GCG3 Cluster: Aldo/keto reductase; n=3; Bacteria|Rep:... 51 3e-05
UniRef50_A7PNT1 Cluster: Chromosome chr8 scaffold_23, whole geno... 51 3e-05
UniRef50_Q27ST7 Cluster: Oxidoreductase; n=2; Eukaryota|Rep: Oxi... 51 3e-05
UniRef50_Q5ASJ7 Cluster: Putative uncharacterized protein; n=1; ... 51 3e-05
UniRef50_UPI000023DAA9 Cluster: hypothetical protein FG00321.1; ... 50 4e-05
UniRef50_A5V463 Cluster: Aldo/keto reductase; n=1; Sphingomonas ... 50 4e-05
UniRef50_O59826 Cluster: Potassium channel subunit; n=9; cellula... 50 4e-05
UniRef50_Q2NFN7 Cluster: Predicted oxidoreductase; n=1; Methanos... 50 4e-05
UniRef50_Q88SS2 Cluster: Oxidoreductase; n=13; Firmicutes|Rep: O... 50 5e-05
UniRef50_Q13GB1 Cluster: Aldo/keto reductase; n=1; Burkholderia ... 50 5e-05
UniRef50_A5VEK4 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:... 50 5e-05
UniRef50_A3U5K6 Cluster: Oxidoreductase, aldo/keto reductase fam... 50 5e-05
UniRef50_Q6TRS1 Cluster: Oxidoreductase; n=1; Ustilago maydis|Re... 50 5e-05
UniRef50_P54569 Cluster: Uncharacterized oxidoreductase yqkF; n=... 50 5e-05
UniRef50_P0A9T5 Cluster: Protein tas; n=88; Bacteria|Rep: Protei... 50 5e-05
UniRef50_A6VR43 Cluster: Aldo/keto reductase precursor; n=3; Pas... 50 7e-05
UniRef50_Q55FL2 Cluster: Putative uncharacterized protein; n=1; ... 50 7e-05
UniRef50_A4RPC9 Cluster: Putative uncharacterized protein; n=1; ... 50 7e-05
UniRef50_Q8EZ83 Cluster: Aldo/keto reductase family protein; n=1... 49 9e-05
UniRef50_Q82JL9 Cluster: Putative oxidoreductase; n=2; Streptomy... 49 9e-05
UniRef50_Q49V75 Cluster: Putative oxidoreductase; n=1; Staphyloc... 49 9e-05
UniRef50_A6EEC4 Cluster: Putative Norsolorinic acid reductase; n... 49 1e-04
UniRef50_Q54CX8 Cluster: Putative uncharacterized protein; n=1; ... 49 1e-04
UniRef50_P49261 Cluster: Rho beta-crystallin; n=1; Lepidodactylu... 49 1e-04
UniRef50_Q0FFB1 Cluster: Aldo/keto reductase; n=1; alpha proteob... 48 2e-04
UniRef50_Q02C17 Cluster: Aldo/keto reductase precursor; n=1; Sol... 48 2e-04
UniRef50_Q5V3K3 Cluster: Oxidoreductase aldo/keto reductase fami... 48 2e-04
UniRef50_Q2JHT1 Cluster: Aldo/keto reductase Tas; n=25; cellular... 48 2e-04
UniRef50_A1SLH1 Cluster: Aldo/keto reductase; n=27; Bacteria|Rep... 48 2e-04
UniRef50_A7T149 Cluster: Predicted protein; n=1; Nematostella ve... 48 2e-04
UniRef50_Q6L0T3 Cluster: Oxidoreductase; n=2; Thermoplasmatales|... 48 2e-04
UniRef50_Q9X123 Cluster: Oxidoreductase, putative; n=4; Bacteria... 48 3e-04
UniRef50_Q0SJ60 Cluster: Possible aldo/keto reductase; n=50; Bac... 48 3e-04
UniRef50_A6E9U0 Cluster: Oxidoreductase; n=1; Pedobacter sp. BAL... 48 3e-04
UniRef50_A5UXT4 Cluster: Aldo/keto reductase; n=2; Roseiflexus|R... 48 3e-04
UniRef50_A0YSM3 Cluster: Probable oxidoreductase; n=1; Lyngbya s... 48 3e-04
UniRef50_A0C161 Cluster: Chromosome undetermined scaffold_141, w... 48 3e-04
UniRef50_Q39MY8 Cluster: Aldo/keto reductase; n=10; Bacteria|Rep... 47 4e-04
UniRef50_Q0BAM8 Cluster: Aldo/keto reductase; n=1; Burkholderia ... 47 4e-04
UniRef50_Q097V7 Cluster: MocA; n=1; Stigmatella aurantiaca DW4/3... 47 4e-04
UniRef50_A7B2Y7 Cluster: Putative uncharacterized protein; n=1; ... 47 4e-04
UniRef50_A1CHK2 Cluster: Aldose 1-epimerase, putative; n=11; Pez... 47 4e-04
UniRef50_Q08NK7 Cluster: Aldo/keto reductase; n=1; Stigmatella a... 47 5e-04
UniRef50_A6VX84 Cluster: Aldo/keto reductase; n=4; Gammaproteoba... 47 5e-04
UniRef50_A5FAZ9 Cluster: Aldo/keto reductase; n=1; Flavobacteriu... 47 5e-04
UniRef50_A0QHX8 Cluster: General stress protein 69; n=2; Mycobac... 47 5e-04
UniRef50_Q1PBI2 Cluster: L-galactose dehydrogenase; n=15; Magnol... 47 5e-04
UniRef50_Q7Q0Y6 Cluster: ENSANGP00000006086; n=7; Coelomata|Rep:... 47 5e-04
UniRef50_Q75DD3 Cluster: ABR094Wp; n=1; Eremothecium gossypii|Re... 47 5e-04
UniRef50_Q9X0R5 Cluster: Oxidoreductase, aldo/keto reductase fam... 46 6e-04
UniRef50_Q60BI7 Cluster: Oxidoreductase, aldo/keto reductase fam... 46 6e-04
UniRef50_Q1GHE2 Cluster: Aldo/keto reductase; n=8; Alphaproteoba... 46 6e-04
UniRef50_Q0AL14 Cluster: Aldo/keto reductase; n=1; Maricaulis ma... 46 6e-04
UniRef50_A5UNN5 Cluster: Predicted oxidoreductase, aldo/keto red... 46 6e-04
UniRef50_Q6MHN8 Cluster: Potassium voltage-gated channel, shaker... 46 8e-04
UniRef50_Q11BU4 Cluster: Aldo/keto reductase; n=11; Proteobacter... 46 8e-04
UniRef50_A4AP98 Cluster: Putative uncharacterized protein; n=1; ... 46 8e-04
UniRef50_Q2H7Q3 Cluster: Putative uncharacterized protein; n=1; ... 46 8e-04
UniRef50_A1RA11 Cluster: Oxidoreductase, aldo/keto reductase fam... 46 0.001
UniRef50_A0UWW6 Cluster: Aldo/keto reductase; n=1; Clostridium c... 46 0.001
UniRef50_A2WWZ1 Cluster: Putative uncharacterized protein; n=1; ... 46 0.001
UniRef50_A4QYG8 Cluster: Putative uncharacterized protein; n=1; ... 46 0.001
UniRef50_P25906 Cluster: Putative oxidoreductase ydbC; n=58; Bac... 46 0.001
UniRef50_Q74DE6 Cluster: Oxidoreductase, aldo/keto reductase fam... 45 0.001
UniRef50_Q3WEJ4 Cluster: Aldo/keto reductase; n=9; Bacteria|Rep:... 45 0.001
UniRef50_Q2AI49 Cluster: Aldo/keto reductase; n=1; Halothermothr... 45 0.001
UniRef50_Q5AQH3 Cluster: Putative uncharacterized protein; n=1; ... 45 0.001
UniRef50_A6RNJ6 Cluster: Putative uncharacterized protein; n=1; ... 45 0.001
UniRef50_Q8ZXA1 Cluster: Aldo-keto reductase family protein; n=3... 45 0.001
UniRef50_A7D5V2 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 45 0.001
UniRef50_Q97KZ9 Cluster: Fe-S oxidoreductase; n=6; cellular orga... 45 0.002
UniRef50_Q7NH41 Cluster: Gll2696 protein; n=1; Gloeobacter viola... 45 0.002
UniRef50_Q64UJ6 Cluster: Putative aldo/keto reductase; n=3; Bact... 45 0.002
UniRef50_Q2SL81 Cluster: Predicted oxidoreductase; n=10; Bacteri... 45 0.002
UniRef50_Q2JB77 Cluster: Aldo/keto reductase; n=1; Frankia sp. C... 45 0.002
UniRef50_Q0LP88 Cluster: Aldo/keto reductase; n=4; Bacteria|Rep:... 45 0.002
UniRef50_Q08P32 Cluster: Aldo/keto reductase; n=3; Proteobacteri... 45 0.002
UniRef50_A7HER9 Cluster: Aldo/keto reductase; n=2; Anaeromyxobac... 45 0.002
UniRef50_A6FYD6 Cluster: Putative aldo/keto reductase; n=1; Ples... 45 0.002
UniRef50_A1RJL6 Cluster: Aldo/keto reductase; n=37; Bacteria|Rep... 45 0.002
UniRef50_A7RXR1 Cluster: Predicted protein; n=3; Eumetazoa|Rep: ... 45 0.002
UniRef50_Q986W6 Cluster: Mlr7180 protein; n=4; Alphaproteobacter... 44 0.003
>UniRef50_Q9Y020 Cluster: 3-dehydroecdysone 3beta-reductase
precursor; n=1; Spodoptera littoralis|Rep:
3-dehydroecdysone 3beta-reductase precursor - Spodoptera
littoralis (Egyptian cotton leafworm)
Length = 345
Score = 274 bits (671), Expect = 2e-72
Identities = 118/184 (64%), Positives = 154/184 (83%)
Frame = +3
Query: 114 LASTMEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTA 293
+++T++VP LKM N R+MPAI LGTYLGFD+ G V SKDKQLR+VVM+AID+GYRHFDTA
Sbjct: 16 MSATIDVPMLKMLNDREMPAIALGTYLGFDKGGAVTSKDKQLRNVVMQAIDLGYRHFDTA 75
Query: 294 SVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYID 473
++Y TE E+GEA++MK++EGV+KRED+F+TTKLWNT H+R +VA A+ ++L K GLDY+D
Sbjct: 76 AIYNTEAEVGEAIRMKIDEGVIKREDVFLTTKLWNTHHKREQVAVAMKETLNKTGLDYVD 135
Query: 474 LYLMHWPIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIK 653
L+LMHWPI LN DYSHS+ D++ETWR E+ ++G K IGLSNFNK Q+ VL+E TIK
Sbjct: 136 LFLMHWPIALNEDYSHSNTDYLETWRATEEMVKLGYTKSIGLSNFNKLQVATVLQECTIK 195
Query: 654 PDAI 665
P A+
Sbjct: 196 PVAL 199
>UniRef50_UPI00015B56A2 Cluster: PREDICTED: similar to GA10458-PA;
n=2; Nasonia vitripennis|Rep: PREDICTED: similar to
GA10458-PA - Nasonia vitripennis
Length = 569
Score = 178 bits (434), Expect = 8e-44
Identities = 86/188 (45%), Positives = 117/188 (62%), Gaps = 11/188 (5%)
Frame = +3
Query: 126 MEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYE 305
M VP++ N+G MP IGLGT+L SK ++ + V AI+VGYRH DTA YE
Sbjct: 1 MPVPTVTFNDGYKMPMIGLGTFL---------SKPGEVAEAVKYAIEVGYRHVDTAFFYE 51
Query: 306 TEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLM 485
E+EIG A++ K+ +G +KREDIF+TTKLW H+ EV A SL+ LG DYIDL+L+
Sbjct: 52 NEKEIGSAIREKINDGTIKREDIFVTTKLWCNSHKEDEVVPACKKSLENLGFDYIDLFLV 111
Query: 486 HWPIGLNA-----------DYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERV 632
HWP + SD D++ETW+G+E+ +R G+ + IGLSNFN +Q+ R+
Sbjct: 112 HWPFAFKSGDALTPRDAAGKIEFSDTDYLETWKGMEECKRQGLARSIGLSNFNSEQIARL 171
Query: 633 LKEGTIKP 656
L IKP
Sbjct: 172 LSSAKIKP 179
Score = 144 bits (349), Expect = 2e-33
Identities = 65/136 (47%), Positives = 92/136 (67%), Gaps = 8/136 (5%)
Frame = +3
Query: 273 YRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKK 452
YRH DTA +Y+ E+ IG A++ K+++G VKRED+F+TTKL H+ +EV A SL
Sbjct: 301 YRHIDTAYLYDNEKYIGNAIREKIKDGTVKREDLFVTTKLSYYAHKESEVVPACKQSLND 360
Query: 453 LGLDYIDLYLMHWPI--------GLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNF 608
LGLDYIDLYL+HWPI + SD D++ETW+G+E+ +R G+ + IG+SNF
Sbjct: 361 LGLDYIDLYLIHWPIRRYFRHNKNASGKLLLSDTDYLETWKGMEECKRQGLARSIGVSNF 420
Query: 609 NKQQLERVLKEGTIKP 656
N +Q+ R+L+ IKP
Sbjct: 421 NSEQITRLLEAAKIKP 436
>UniRef50_UPI00015B56A3 Cluster: PREDICTED: similar to aldo-keto
reductase; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to aldo-keto reductase - Nasonia vitripennis
Length = 321
Score = 169 bits (410), Expect = 7e-41
Identities = 81/187 (43%), Positives = 120/187 (64%), Gaps = 11/187 (5%)
Frame = +3
Query: 129 EVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYET 308
+V + +++G +P +GLGT+ G + ++ + V AID GYRHFD AS Y
Sbjct: 4 KVDEITLSDGNKVPVLGLGTWQGGND-------PDEVENAVKLAIDAGYRHFDCASFYGN 56
Query: 309 EQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMH 488
E EIG+A++ K+++GVVKRED+F+ TK+WN + ++ V A SLKKLGL YIDLYL+H
Sbjct: 57 EAEIGKAIQEKIDQGVVKREDLFVVTKVWNDERKQELVVAACKRSLKKLGLGYIDLYLVH 116
Query: 489 WPIGLNADYSH-----------SDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL 635
WP Y + +VD++ETWRG+E+ ++G+ + IG+SNFN QQL R+L
Sbjct: 117 WPFSYPILYQYIVLPTYNAVTLDEVDYIETWRGMEECIKLGLTRSIGVSNFNSQQLTRLL 176
Query: 636 KEGTIKP 656
+ +IKP
Sbjct: 177 ESASIKP 183
>UniRef50_Q7JVH6 Cluster: LD24696p; n=2; Sophophora|Rep: LD24696p -
Drosophila melanogaster (Fruit fly)
Length = 311
Score = 163 bits (395), Expect = 5e-39
Identities = 80/182 (43%), Positives = 114/182 (62%), Gaps = 8/182 (4%)
Frame = +3
Query: 135 PSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQ 314
P++++NNGR+MP +GLGT+ F+ + ++ A+DVGYRH DTA VYE E
Sbjct: 6 PTIRLNNGREMPTLGLGTWKSFESDAYHSTR---------HALDVGYRHLDTAFVYENEA 56
Query: 315 EIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 494
E+G+A+ K+ EGVV RE++F+TTKL H V +A SL LGL+Y+DLYLMH P
Sbjct: 57 EVGQAISEKIAEGVVTREEVFVTTKLGGIHHDPALVERACRLSLSNLGLEYVDLYLMHMP 116
Query: 495 IG--------LNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTI 650
+G ++ +DVD+++TWR +E +G+ + IGLSNFN Q ERVL I
Sbjct: 117 VGQKFHNDSNVHGTLELTDVDYLDTWREMEKLVDLGLTRSIGLSNFNAAQTERVLANCRI 176
Query: 651 KP 656
+P
Sbjct: 177 RP 178
>UniRef50_Q7QK25 Cluster: ENSANGP00000019775; n=2; Anopheles gambiae
str. PEST|Rep: ENSANGP00000019775 - Anopheles gambiae
str. PEST
Length = 319
Score = 162 bits (393), Expect = 8e-39
Identities = 85/192 (44%), Positives = 123/192 (64%), Gaps = 16/192 (8%)
Frame = +3
Query: 129 EVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYET 308
+VP+++ +NG ++P +G GTYL Q G Q ++V +AID+GYRH DTA +YE
Sbjct: 4 QVPTVRFSNGYEIPVLGYGTYLA--QKG-------QCVELVKKAIDLGYRHIDTAFLYEN 54
Query: 309 EQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMH 488
E EIG+A++ K+ EGV++RED+F+TTKLWNT H V +A S L + YIDL+LMH
Sbjct: 55 EVEIGQAIRDKIAEGVIRREDVFVTTKLWNTFHDPQHVEEAFRRSFDMLDIGYIDLFLMH 114
Query: 489 WPIGLN-ADYSH--------------SDVDFMETWRGLED-AQRMGIVKGIGLSNFNKQQ 620
P+G+ + Y + SDVD++ETW+ +E G V+ IGLSNFN +Q
Sbjct: 115 SPMGVQFSGYEYADMQPKDAAGNMLFSDVDYVETWKAMEKLVTAGGRVRSIGLSNFNSEQ 174
Query: 621 LERVLKEGTIKP 656
+ER+L+ T+KP
Sbjct: 175 IERILQIATVKP 186
>UniRef50_Q17DN0 Cluster: Aldo-keto reductase; n=5; Culicidae|Rep:
Aldo-keto reductase - Aedes aegypti (Yellowfever
mosquito)
Length = 324
Score = 161 bits (390), Expect = 2e-38
Identities = 84/190 (44%), Positives = 113/190 (59%), Gaps = 15/190 (7%)
Frame = +3
Query: 132 VPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETE 311
+P++K+NNG +MPAIGLGT + SK + VM AID G+RH DTA Y E
Sbjct: 6 IPTVKLNNGLEMPAIGLGTSM---------SKGDECCKAVMTAIDEGFRHIDTAYNYRNE 56
Query: 312 QEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHW 491
+G A++ K+EEGVV RE++F+TTKLWNT H V A SL+ LGLDY+DL+L+H
Sbjct: 57 DVVGRAIRAKIEEGVVTREELFVTTKLWNTFHHPDHVPMAFGKSLEHLGLDYVDLFLIHM 116
Query: 492 PIGL---------------NADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLE 626
P G N + SD D+++TW+ +E G V IG+SNFN +QLE
Sbjct: 117 PFGYEFNGWDPEKRTPLDDNGNVLCSDDDYVDTWKAMEKLLESGRVHSIGVSNFNSEQLE 176
Query: 627 RVLKEGTIKP 656
R+L +KP
Sbjct: 177 RILANCRVKP 186
>UniRef50_Q8VC28 Cluster: Aldo-keto reductase family 1 member C13;
n=11; Theria|Rep: Aldo-keto reductase family 1 member
C13 - Mus musculus (Mouse)
Length = 323
Score = 161 bits (390), Expect = 2e-38
Identities = 85/182 (46%), Positives = 119/182 (65%), Gaps = 11/182 (6%)
Frame = +3
Query: 141 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 320
+K+N+G +PA+G GTY V KSK + A+DVGYRH DTA Y+ E+EI
Sbjct: 8 VKLNDGHLIPALGFGTY---KPKEVPKSKSLE---AACLALDVGYRHVDTAYAYQVEEEI 61
Query: 321 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 500
G+A++ K++ GVVKRED+FITTKLW T R V A+ SLKKL LDY+DLY+MH+P+
Sbjct: 62 GQAIQSKIKAGVVKREDLFITTKLWCTCFRPELVKPALEKSLKKLQLDYVDLYIMHYPVP 121
Query: 501 LNA---DYSHSD--------VDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGT 647
+ + D+ ++ VDF +TW LE+ + G+VK IG+SNFN +QLER+L +
Sbjct: 122 MKSGDNDFPVNEQGKSLLDTVDFCDTWERLEECKDAGLVKSIGVSNFNHRQLERILNKPG 181
Query: 648 IK 653
+K
Sbjct: 182 LK 183
>UniRef50_Q2LZ66 Cluster: GA19341-PA; n=2; Endopterygota|Rep:
GA19341-PA - Drosophila pseudoobscura (Fruit fly)
Length = 315
Score = 159 bits (385), Expect = 7e-38
Identities = 76/189 (40%), Positives = 117/189 (61%), Gaps = 12/189 (6%)
Frame = +3
Query: 126 MEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYE 305
M PS +++GR+MP +GLGT+ +S + + V AID+GYRHFD A +Y
Sbjct: 1 MSTPSFLLSSGRNMPMVGLGTW---------RSPPEVVAQAVKDAIDIGYRHFDCAHIYG 51
Query: 306 TEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLM 485
E +G A++ K++EG+V R+++FIT+KLWNT H+ V A SL+ LG+DY+DLYLM
Sbjct: 52 NELHVGVAIREKIQEGLVTRDELFITSKLWNTFHKPELVRAACETSLRNLGIDYLDLYLM 111
Query: 486 HWPIGLNADYS------------HSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLER 629
HWP+ + + D+D+++TW+ +ED G+V IG+SNFN++Q+ R
Sbjct: 112 HWPMAYKSGDNLYPTCPDTGKAVFEDIDYLDTWKAMEDLVDSGLVNAIGVSNFNEKQINR 171
Query: 630 VLKEGTIKP 656
+L +KP
Sbjct: 172 LLCLAKLKP 180
>UniRef50_Q8WRT0 Cluster: 3-dehydrecdysone 3b-reductase; n=1;
Trichoplusia ni|Rep: 3-dehydrecdysone 3b-reductase -
Trichoplusia ni (Cabbage looper)
Length = 308
Score = 158 bits (384), Expect = 1e-37
Identities = 72/176 (40%), Positives = 117/176 (66%)
Frame = +3
Query: 129 EVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYET 308
+ P ++N+G +P++ LGT+ GF G + ++R V+ AI GYRH DTA++Y
Sbjct: 23 KAPLKQLNDGNAIPSLALGTF-GF---GDIP----KVRQAVLWAIQAGYRHIDTAALYGN 74
Query: 309 EQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMH 488
E+E+G+ + +++G+VKRE++F+TTKLWN +H R +V A+ +SL KLGL Y+DLYL+H
Sbjct: 75 EEEVGKGIADAIQQGLVKREELFVTTKLWNDKHGRHQVVPALRESLTKLGLSYVDLYLIH 134
Query: 489 WPIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
P N + D+D + TW G+E+A+++G+ K IG+SNF+ L+R++ P
Sbjct: 135 SPEATNENGDPVDIDVLNTWNGMEEAKKLGLAKSIGVSNFDTALLDRLIAGSNTVP 190
>UniRef50_UPI0000588153 Cluster: PREDICTED: hypothetical protein;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 333
Score = 156 bits (378), Expect = 5e-37
Identities = 78/189 (41%), Positives = 113/189 (59%), Gaps = 13/189 (6%)
Frame = +3
Query: 138 SLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 317
S+ + +G MP +GLGT+ K K ++ + A+D GYRHFD A +Y E+E
Sbjct: 4 SVTLPSGHAMPLVGLGTW---------KLKADEVAGAIGAAVDAGYRHFDCALIYGNEKE 54
Query: 318 IGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 497
+G A++ ++ +KRED+FITTK+WNT H + +VA+ N SL L LDYIDLY+MHWP+
Sbjct: 55 VGVALREAMQRLGLKREDVFITTKVWNTFHAKEDVAECFNRSLTDLQLDYIDLYIMHWPL 114
Query: 498 GL-------------NADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLK 638
G D +SDV ++ETW +ED + G K +GLSNFN +QL+ VL+
Sbjct: 115 GFQNLGPTVMFPRTETGDIVYSDVHYLETWSAMEDLVKTGKCKSLGLSNFNSKQLDDVLQ 174
Query: 639 EGTIKPDAI 665
T+ P +
Sbjct: 175 HSTVPPSVL 183
>UniRef50_Q7PCV3 Cluster: ENSANGP00000031808; n=9;
Endopterygota|Rep: ENSANGP00000031808 - Anopheles
gambiae str. PEST
Length = 316
Score = 156 bits (378), Expect = 5e-37
Identities = 82/187 (43%), Positives = 110/187 (58%), Gaps = 12/187 (6%)
Frame = +3
Query: 132 VPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETE 311
VP+ NG +P GLGT+ S Q+ V AIDVGYRH D A VY+ E
Sbjct: 6 VPNAIFKNGNSIPMFGLGTW---------NSPPGQVAQAVKDAIDVGYRHIDCAHVYQNE 56
Query: 312 QEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHW 491
E+GE + K+ EGVVKRED+F+T+KLWNT HR V A +L+ L LDY+DLYL+HW
Sbjct: 57 HEVGEGIAAKIAEGVVKREDLFVTSKLWNTFHRPDLVEGACKTTLQNLKLDYLDLYLIHW 116
Query: 492 PIG---------LNAD---YSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL 635
P+G + D + SD D+++TW +E G+V+ IG+SNFN +Q++RVL
Sbjct: 117 PVGYQEGTELFPMGPDGKTFLFSDADYVDTWPEMEKLVDAGLVRNIGVSNFNAKQVQRVL 176
Query: 636 KEGTIKP 656
I P
Sbjct: 177 DVARIPP 183
>UniRef50_Q9VTL0 Cluster: CG6083-PA; n=4; Diptera|Rep: CG6083-PA -
Drosophila melanogaster (Fruit fly)
Length = 322
Score = 154 bits (374), Expect = 2e-36
Identities = 73/190 (38%), Positives = 117/190 (61%), Gaps = 13/190 (6%)
Frame = +3
Query: 126 MEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYE 305
M P+ ++NG++MP +GLGT+ +S + + V AID+GYRHFD A +Y
Sbjct: 1 MSTPNFLLSNGKNMPMLGLGTW---------RSPPEVVTQAVKDAIDIGYRHFDCAHIYG 51
Query: 306 TEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLM 485
E ++G A++ K++EGVV R+++FIT+KLWNT H+ V A S++ LG+ Y++LYLM
Sbjct: 52 NEAQVGAALREKMDEGVVTRDELFITSKLWNTHHKPDLVRPACETSIRNLGVKYLNLYLM 111
Query: 486 HWPIGLNADYSH-------------SDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLE 626
HWP+ + + D+D+++TWR +E+ G+ + IG+SNFN+QQ+
Sbjct: 112 HWPMAYKSGSDNLYPTCPDTNKAAFEDIDYVDTWRAMENLVDEGLCQAIGVSNFNEQQMN 171
Query: 627 RVLKEGTIKP 656
R+L +KP
Sbjct: 172 RLLSVAKLKP 181
>UniRef50_P45376 Cluster: Aldose reductase; n=21; Bilateria|Rep:
Aldose reductase - Mus musculus (Mouse)
Length = 316
Score = 152 bits (368), Expect = 8e-36
Identities = 81/182 (44%), Positives = 112/182 (61%), Gaps = 11/182 (6%)
Frame = +3
Query: 141 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 320
L++NNG MP +GLGT+ KS Q+ + V AID+GYRH D A VY+ E+E+
Sbjct: 5 LELNNGTKMPTLGLGTW---------KSPPGQVTEAVKVAIDLGYRHIDCAQVYQNEKEV 55
Query: 321 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 500
G A++ K++E VVKR+D+FI +KLW T H ++ V A +L L LDY+DLYL+HWP G
Sbjct: 56 GVALQEKLKEQVVKRQDLFIVSKLWCTFHDKSMVKGAFQKTLSDLQLDYLDLYLIHWPTG 115
Query: 501 L--NADY---------SHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGT 647
DY SD DF++TW +E G+VK IG+SNFN Q+ER+L +
Sbjct: 116 FKPGPDYFPLDASGNVIPSDTDFVDTWTAMEQLVDEGLVKTIGVSNFNPLQIERILNKPG 175
Query: 648 IK 653
+K
Sbjct: 176 LK 177
>UniRef50_Q9NAI5 Cluster: Putative uncharacterized protein; n=3;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 316
Score = 151 bits (367), Expect = 1e-35
Identities = 78/186 (41%), Positives = 112/186 (60%), Gaps = 11/186 (5%)
Frame = +3
Query: 132 VPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETE 311
V SLK+N+G +PAIGLGT+ +SK ++ + A+ GYRH D A VY+ +
Sbjct: 2 VQSLKLNSGYSIPAIGLGTW---------QSKPGEVAAAIKTAVAAGYRHIDCAHVYQNQ 52
Query: 312 QEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHW 491
+E+GEA+K ++EG VKRE++FIT+K+WNT H + + I+ L L L Y+DL L+HW
Sbjct: 53 KEVGEALKEILDEGKVKREELFITSKVWNTFHSEAKAHENIDIILSDLQLSYVDLMLIHW 112
Query: 492 -----------PIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLK 638
P G N +SDVD++ETW+ E AQ+ G + IGLSNF Q++RV
Sbjct: 113 PQGYAEGAELFPAGENGKMRYSDVDYLETWKAFEAAQKAGKCRSIGLSNFTHSQIQRVWD 172
Query: 639 EGTIKP 656
+KP
Sbjct: 173 AAEVKP 178
>UniRef50_Q41399 Cluster: Chalcone reductase; n=4;
eudicotyledons|Rep: Chalcone reductase - Sesbania
rostrata
Length = 322
Score = 149 bits (361), Expect = 6e-35
Identities = 74/186 (39%), Positives = 116/186 (62%), Gaps = 10/186 (5%)
Frame = +3
Query: 129 EVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYET 308
++P + +N+G MP IG+GT + + V L + + AI VGYRHFD+ASVY T
Sbjct: 5 KIPEVLLNSGHKMPVIGMGTSVESRPSNDV------LASIFVDAIQVGYRHFDSASVYGT 58
Query: 309 EQEIGEAVKMKVEEGVVK-REDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLM 485
E+ IG AV +E+G++K R+++FIT+K WNT + A+ +LKKLG++Y+DLYL+
Sbjct: 59 EEAIGMAVSKAIEQGLIKSRDEVFITSKPWNTDAHHDLIVPALKTTLKKLGMEYVDLYLI 118
Query: 486 HWPIGLNAD------YSHSDV---DFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLK 638
HWP+ L D +S D+ D TW+ +E+ R+G+ K IG+ N+ ++L ++L+
Sbjct: 119 HWPVRLRHDLENPVIFSKEDLLPFDIEGTWKAMEECYRLGLAKSIGICNYGTKKLTKLLE 178
Query: 639 EGTIKP 656
TI P
Sbjct: 179 IATIPP 184
>UniRef50_Q8K023 Cluster: Aldo-keto reductase family 1 member C18;
n=72; Tetrapoda|Rep: Aldo-keto reductase family 1 member
C18 - Mus musculus (Mouse)
Length = 323
Score = 149 bits (361), Expect = 6e-35
Identities = 72/186 (38%), Positives = 115/186 (61%), Gaps = 11/186 (5%)
Frame = +3
Query: 129 EVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYET 308
++ +++N+G +P +G GTY + +K K + + AIDVG+ H D + +Y+
Sbjct: 4 KIQKIELNDGHSIPVLGFGTYATEEH---LKKKSMESTKI---AIDVGFCHIDCSHLYQN 57
Query: 309 EQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMH 488
E+EIG+A+ K+E+G VKREDIF T+KLW+T HR V ++ +SL+KL LDY+DLYL+H
Sbjct: 58 EEEIGQAILSKIEDGTVKREDIFYTSKLWSTSHRPELVRPSLENSLRKLNLDYVDLYLIH 117
Query: 489 WPIGL-----------NADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL 635
+P+ L + + VD +TW +E + G+ K IG+SNFN++QLE +L
Sbjct: 118 FPVSLKPGNELLPKDEHGNLIFDTVDLCDTWEAMEKCKDAGLAKSIGVSNFNRRQLEMIL 177
Query: 636 KEGTIK 653
+ +K
Sbjct: 178 NKPGLK 183
>UniRef50_Q96JD6 Cluster: Aldo-keto reductase family 1 member C-like
protein 2; n=37; Euteleostomi|Rep: Aldo-keto reductase
family 1 member C-like protein 2 - Homo sapiens (Human)
Length = 320
Score = 113 bits (273), Expect(2) = 4e-34
Identities = 52/113 (46%), Positives = 75/113 (66%)
Frame = +3
Query: 162 DMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMK 341
D+PA+GL ++ K+ ++ + V AID GYRHFD A Y E+E+G ++ K
Sbjct: 3 DIPAVGLSSW---------KASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCK 53
Query: 342 VEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 500
++EG V+RED+FI TKLW T H+++ V A SLK L L+Y+DLYL+HWP+G
Sbjct: 54 IKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMG 106
Score = 54.0 bits (124), Expect(2) = 4e-34
Identities = 22/40 (55%), Positives = 30/40 (75%)
Frame = +3
Query: 522 SDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKE 641
SD DF++TW +ED G+VK IG+SNFN +QLER+L +
Sbjct: 144 SDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNK 183
>UniRef50_Q96JD6-2 Cluster: Isoform 2 of Q96JD6 ; n=4;
Catarrhini|Rep: Isoform 2 of Q96JD6 - Homo sapiens
(Human)
Length = 263
Score = 113 bits (273), Expect(2) = 4e-34
Identities = 52/113 (46%), Positives = 75/113 (66%)
Frame = +3
Query: 162 DMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMK 341
D+PA+GL ++ K+ ++ + V AID GYRHFD A Y E+E+G ++ K
Sbjct: 3 DIPAVGLSSW---------KASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCK 53
Query: 342 VEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 500
++EG V+RED+FI TKLW T H+++ V A SLK L L+Y+DLYL+HWP+G
Sbjct: 54 IKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMG 106
Score = 54.0 bits (124), Expect(2) = 4e-34
Identities = 22/40 (55%), Positives = 30/40 (75%)
Frame = +3
Query: 522 SDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKE 641
SD DF++TW +ED G+VK IG+SNFN +QLER+L +
Sbjct: 144 SDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNK 183
>UniRef50_P15121 Cluster: Aldose reductase; n=72; Eumetazoa|Rep:
Aldose reductase - Homo sapiens (Human)
Length = 316
Score = 144 bits (350), Expect = 1e-33
Identities = 77/182 (42%), Positives = 107/182 (58%), Gaps = 11/182 (6%)
Frame = +3
Query: 141 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 320
L +NNG MP +GLGT+ KS Q+ + V AIDVGYRH D A VY+ E E+
Sbjct: 5 LLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEV 55
Query: 321 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 500
G A++ K+ E VVKRE++FI +KLW T H + V A +L L LDY+DLYL+HWP G
Sbjct: 56 GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115
Query: 501 L-----------NADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGT 647
+ + SD + ++TW +E+ G+VK IG+SNFN Q+E +L +
Sbjct: 116 FKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPG 175
Query: 648 IK 653
+K
Sbjct: 176 LK 177
>UniRef50_Q54B70 Cluster: Aldehyde reductase; n=2; Dictyostelium
discoideum|Rep: Aldehyde reductase - Dictyostelium
discoideum AX4
Length = 297
Score = 144 bits (349), Expect = 2e-33
Identities = 80/187 (42%), Positives = 107/187 (57%), Gaps = 11/187 (5%)
Frame = +3
Query: 135 PSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQ 314
PS K+++G +P +G GT+ K++ + V A+D GYRH D A+VY E+
Sbjct: 3 PSFKLSSGHKIPLVGFGTW---------KAETTLVGKAVEVALDAGYRHIDCAAVYLNEK 53
Query: 315 EIGEAVKMK-VEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHW 491
E+GEA K E VKRED+FIT+KLWNT H++ V A+ +L LGL Y+DLYL+HW
Sbjct: 54 EVGEAFTKKFTTEATVKREDVFITSKLWNTFHKKEHVRPALERTLSDLGLQYLDLYLVHW 113
Query: 492 PIGLNADYSHSD----------VDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKE 641
P+ +Y+ +D V ETW +E G+VK IGLSNFN Q L VL
Sbjct: 114 PVAF--EYTSNDIQTSGSTQEFVSIRETWEEMEKLVDAGLVKSIGLSNFNVQGLMEVLSY 171
Query: 642 GTIKPDA 662
IKP A
Sbjct: 172 ARIKPAA 178
>UniRef50_A5E082 Cluster: GCY protein; n=4; Saccharomycetales|Rep:
GCY protein - Lodderomyces elongisporus (Yeast)
(Saccharomyces elongisporus)
Length = 295
Score = 144 bits (348), Expect = 2e-33
Identities = 72/166 (43%), Positives = 112/166 (67%), Gaps = 3/166 (1%)
Frame = +3
Query: 147 MNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGE 326
+NNG +PAIGLGT+L +++ K+ + A+ GY+H DTA+ Y E ++G
Sbjct: 14 LNNGLKIPAIGLGTWLADEEDAAYKA--------TLTALKNGYKHIDTAAAYGNEDQVGR 65
Query: 327 AVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLN 506
A+ + GV R++IF+TTKLWN QH+ E A+++SLKKLGL+Y+DLYL+HWP+ ++
Sbjct: 66 AI---ADSGV-SRDEIFVTTKLWNDQHKDPE--GALDESLKKLGLEYVDLYLIHWPLSVD 119
Query: 507 --ADYSHSDVDFMETWRGLEDAQRMG-IVKGIGLSNFNKQQLERVL 635
+ + D DF++TWR L+ + G VK IG+SNFNK++L+++L
Sbjct: 120 PKTEKPYDDYDFVDTWRNLQKIYKEGKKVKAIGVSNFNKKKLDKLL 165
>UniRef50_P14550 Cluster: Alcohol dehydrogenase [NADP+]; n=44;
Bilateria|Rep: Alcohol dehydrogenase [NADP+] - Homo
sapiens (Human)
Length = 325
Score = 140 bits (340), Expect = 2e-32
Identities = 75/189 (39%), Positives = 110/189 (58%), Gaps = 12/189 (6%)
Frame = +3
Query: 126 MEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYE 305
M + ++ G+ MP IGLGT+ KS+ Q++ V A+ VGYRH D A++Y
Sbjct: 1 MAASCVLLHTGQKMPLIGLGTW---------KSEPGQVKAAVKYALSVGYRHIDCAAIYG 51
Query: 306 TEQEIGEAVKMKVEEG-VVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYL 482
E EIGEA+K V G V RE++F+T+KLWNT+H +V A+ +L L L+Y+DLYL
Sbjct: 52 NEPEIGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYL 111
Query: 483 MHWPIGL---------NAD--YSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLER 629
MHWP NAD + + ETW+ LE G+V+ +GLSNFN +Q++
Sbjct: 112 MHWPYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDD 171
Query: 630 VLKEGTIKP 656
+L +++P
Sbjct: 172 ILSVASVRP 180
>UniRef50_Q8CI22 Cluster: 2310005E10Rik protein; n=30;
Tetrapoda|Rep: 2310005E10Rik protein - Mus musculus
(Mouse)
Length = 316
Score = 140 bits (339), Expect = 3e-32
Identities = 72/177 (40%), Positives = 105/177 (59%), Gaps = 11/177 (6%)
Frame = +3
Query: 156 GRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVK 335
G MP +GLGT+ KS ++R+ V AID GYRH D A VY+ E E+GEA++
Sbjct: 10 GAKMPIVGLGTW---------KSPPAKVREAVKVAIDAGYRHIDCAYVYQNESEVGEAIQ 60
Query: 336 MKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNA-- 509
K++E VKRED+FI +KLW+T ++ V +A ++L L LDY+DLYL+HWP G +
Sbjct: 61 EKIQEKAVKREDLFIVSKLWSTFFEKSLVKKAFQNTLSDLKLDYLDLYLIHWPQGFQSGN 120
Query: 510 ---------DYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIK 653
S F++ W +E+ G+VK +G+SNFN Q+ER+L + +K
Sbjct: 121 VFLPTDDKGSILSSKYTFLDAWEAMEELVDQGLVKALGVSNFNHFQIERLLNKPGLK 177
>UniRef50_Q7PLK6 Cluster: CG40064-PA; n=1; Drosophila
melanogaster|Rep: CG40064-PA - Drosophila melanogaster
(Fruit fly)
Length = 361
Score = 140 bits (339), Expect = 3e-32
Identities = 66/158 (41%), Positives = 104/158 (65%), Gaps = 12/158 (7%)
Frame = +3
Query: 219 KSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWN 398
K + Q V AI+ G+RHFDTA YE E+EIGEA++ +++ G + RE+IF+TTKLWN
Sbjct: 40 KLRGYQCSAAVHCAIETGFRHFDTAYYYENEKEIGEALRTQIKMGNISRENIFLTTKLWN 99
Query: 399 TQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG-----------LNADYSHS-DVDFME 542
T H +V + L+ LG YIDLYLMH+P+G ++ D + ++D+++
Sbjct: 100 THHDPRDVRRICEKQLELLGFSYIDLYLMHFPVGYKYVCDEILMPMSGDELQTVEIDYLD 159
Query: 543 TWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
TWR +E+ ++G+V+ IGLSNFN +Q++R+++ + KP
Sbjct: 160 TWRAMENLVKLGMVRSIGLSNFNMEQIQRIIQCSSSKP 197
>UniRef50_A3U9Y0 Cluster: Aldehyde reductase; n=5;
Bacteroidetes|Rep: Aldehyde reductase - Croceibacter
atlanticus HTCC2559
Length = 316
Score = 140 bits (338), Expect = 4e-32
Identities = 69/174 (39%), Positives = 106/174 (60%), Gaps = 11/174 (6%)
Frame = +3
Query: 138 SLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 317
+LK +G +P+IGLGT+ KS + ++ V A++ GY+H D A+ Y+ E
Sbjct: 3 TLKFRDGDSIPSIGLGTW---------KSDPEDVKKAVKIALENGYKHIDCAAAYDNEDA 53
Query: 318 IGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 497
+GEA K E G VKREDIF+T+KLWN H++ +V A+ +LK L LDY+DLYLMHWP+
Sbjct: 54 VGEAFKESFESGNVKREDIFVTSKLWNNAHKKEDVIPALKKTLKDLNLDYLDLYLMHWPV 113
Query: 498 GLNAD---YSHSDVDFM--------ETWRGLEDAQRMGIVKGIGLSNFNKQQLE 626
+ D D++ ET + +A++ G++K +G+SNF+K++LE
Sbjct: 114 AFKPSVNGFPEKDEDYLSLEEAPLHETLNAMIEAKKQGLIKHVGVSNFSKEKLE 167
>UniRef50_Q16K66 Cluster: Aldo-keto reductase; n=2; Aedes
aegypti|Rep: Aldo-keto reductase - Aedes aegypti
(Yellowfever mosquito)
Length = 303
Score = 138 bits (335), Expect = 8e-32
Identities = 78/180 (43%), Positives = 108/180 (60%), Gaps = 8/180 (4%)
Frame = +3
Query: 141 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 320
L +NNG +P IGLGTY +GV K A++ GYR DTA VY EQ +
Sbjct: 2 LALNNGHSIPPIGLGTYKITGSDGVAAIKS---------AVEFGYRLIDTAFVYNNEQVV 52
Query: 321 GEAVKMKVEEGV-VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 497
G+A++ +G + RED+FI +KL T HR V + SL++LGLDY+DLYLMH P+
Sbjct: 53 GQALREIFSQGNDINREDVFIVSKLGPTFHRPEAVEKGCRLSLERLGLDYVDLYLMHTPV 112
Query: 498 -----GLNADYSHSD--VDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
G D S D V +ETW+ LE+ QR G+V+ IG+SNFN++QL ++ G+I+P
Sbjct: 113 AARDSGDGNDRSEIDDEVTPLETWKALEECQRKGLVRSIGVSNFNEEQLMEIVTHGSIRP 172
>UniRef50_Q0VGY1 Cluster: 3-alpha-hydroxysteroid dehydrogenase;
n=13; Tetrapoda|Rep: 3-alpha-hydroxysteroid
dehydrogenase - Xenopus tropicalis (Western clawed frog)
(Silurana tropicalis)
Length = 324
Score = 138 bits (334), Expect = 1e-31
Identities = 71/182 (39%), Positives = 103/182 (56%), Gaps = 11/182 (6%)
Frame = +3
Query: 141 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 320
+++N+G MP IG GTY K + AIDVGYRH D A +Y E+E+
Sbjct: 9 VELNDGHKMPVIGFGTY------APPKFPKSLAEEGTKVAIDVGYRHIDCAFLYGNEEEV 62
Query: 321 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 500
G A++ K+ +G VKRED+F T KLW+T H V A+ SLK L LDY+DL+++H P+
Sbjct: 63 GRAIRAKIADGTVKREDVFYTGKLWSTSHTPERVRPALEKSLKDLQLDYMDLFIIHMPME 122
Query: 501 L-----------NADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGT 647
N + + + D +TW+ LE + G+V+ IG+SNFN +QLE +L
Sbjct: 123 FKPGDDLFPADENGKFIYHNTDLRDTWKALEKCKDAGLVRSIGVSNFNHKQLELILNMPG 182
Query: 648 IK 653
+K
Sbjct: 183 LK 184
>UniRef50_Q96UH3 Cluster: Aldehyde reductase; n=13;
Pezizomycotina|Rep: Aldehyde reductase - Coccidioides
posadasii
Length = 314
Score = 138 bits (334), Expect = 1e-31
Identities = 73/184 (39%), Positives = 110/184 (59%), Gaps = 11/184 (5%)
Frame = +3
Query: 138 SLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 317
+ ++N G D+PAIG GT+ D+N D V+ A+ GYRH DTA+VY TE+
Sbjct: 7 TFRLNTGEDIPAIGFGTWQ--DENAQ--------EDAVLTALSAGYRHIDTAAVYGTEKA 56
Query: 318 IGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 497
IG A+ + R+++FIT+KLWN +HR +V QAI+ SLK L +DY+DLYLMHWP
Sbjct: 57 IGRALA----RSRLSRDELFITSKLWNNKHRPEDVEQAIDQSLKNLEIDYLDLYLMHWPA 112
Query: 498 GL-----------NADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEG 644
+ D+D+++T++ +E + G K IG+SNF+K ++ER+L+
Sbjct: 113 AFAPGDDMFPKDSQGNSKTVDIDYVDTYKAMEKLVKSGKTKAIGISNFSKGEMERLLESC 172
Query: 645 TIKP 656
+I P
Sbjct: 173 SIVP 176
>UniRef50_Q23320 Cluster: Putative uncharacterized protein; n=4;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 320
Score = 138 bits (333), Expect = 1e-31
Identities = 72/170 (42%), Positives = 104/170 (61%), Gaps = 1/170 (0%)
Frame = +3
Query: 129 EVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYET 308
+VP ++NG MP+IGLGT+ + G + V+ A+ GYRH DTA++Y+
Sbjct: 4 KVPIFTLSNGVLMPSIGLGTWQMTGEEG---------KTVIRNAVLAGYRHIDTATLYQN 54
Query: 309 EQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMH 488
E +IG+A+ EG++KREDIFITTK + + V +A+ +SLK+L LDY+DLYL H
Sbjct: 55 EHQIGDALAELFAEGILKREDIFITTKAFCHEVAPDVVEEALRNSLKRLRLDYVDLYLAH 114
Query: 489 WPIGLNADYS-HSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL 635
P D S SDV + WRG E +G+ K IG+SNFN+ Q+ R++
Sbjct: 115 IPASTKDDGSFRSDVKVEDIWRGFEKVYGLGLTKAIGVSNFNESQIVRIM 164
>UniRef50_Q03TW0 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=1; Lactobacillus brevis ATCC
367|Rep: Aldo/keto reductase of diketogulonate reductase
family - Lactobacillus brevis (strain ATCC 367 / JCM
1170)
Length = 293
Score = 137 bits (332), Expect = 2e-31
Identities = 70/176 (39%), Positives = 105/176 (59%)
Frame = +3
Query: 129 EVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYET 308
++P L MNNG +P +GLG + V ++D ++ + A+ GYRH DTA+ Y
Sbjct: 10 DIPDLPMNNGHQIPQLGLGVFQ------VDNAEDT--KNAIKWALAAGYRHIDTAAYYGN 61
Query: 309 EQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMH 488
EQ +GEA++ E V R+ IF+T+KLWN+ E A ++L KLGLDY+DLYL+H
Sbjct: 62 EQWVGEAIR----ESDVPRDQIFVTSKLWNSVRGYDETQAAFQETLDKLGLDYLDLYLIH 117
Query: 489 WPIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
WP ++++WR +ED + G +K IG+SNFN+ Q+ +L GT+KP
Sbjct: 118 WPA----------PGYLDSWRAMEDLYKAGKIKNIGVSNFNQTQMADILAHGTVKP 163
>UniRef50_Q0IBY6 Cluster: Alcohol dehydrogenase; n=2;
Chroococcales|Rep: Alcohol dehydrogenase - Synechococcus
sp. (strain CC9311)
Length = 336
Score = 137 bits (331), Expect = 3e-31
Identities = 70/198 (35%), Positives = 119/198 (60%), Gaps = 10/198 (5%)
Frame = +3
Query: 96 VENLTELASTMEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGY 275
V N+ ++ TM+ SL +NG MP +GLGT KS+ +Q+ V AI +GY
Sbjct: 9 VNNIKDVIPTMQYASL--SNGDRMPLLGLGTG---------KSESRQVYKSVREAIKIGY 57
Query: 276 RHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKL 455
RH D AS+Y E+E+G+A++ ++ + R +++IT+KLW+ H + V A++ SL+ L
Sbjct: 58 RHIDCASIYGNEEEVGDAIRDAIQNHEITRSELWITSKLWSNCHGKNHVEAALSQSLQNL 117
Query: 456 GLDYIDLYLMHWPIGLNADYSHSD-VD---------FMETWRGLEDAQRMGIVKGIGLSN 605
G+DY++LYL+HWP+G+ + + ++ VD ETW +E + G+ K IG+SN
Sbjct: 118 GVDYLNLYLIHWPVGIRPEKTFAESVDDLLTPEESPISETWEAMESTRDKGLTKHIGVSN 177
Query: 606 FNKQQLERVLKEGTIKPD 659
F ++L++++ KP+
Sbjct: 178 FTVKKLQQLVSHCKQKPE 195
>UniRef50_A3C1Z7 Cluster: Putative uncharacterized protein; n=2;
Oryza sativa (japonica cultivar-group)|Rep: Putative
uncharacterized protein - Oryza sativa subsp. japonica
(Rice)
Length = 288
Score = 137 bits (331), Expect = 3e-31
Identities = 71/188 (37%), Positives = 117/188 (62%), Gaps = 11/188 (5%)
Frame = +3
Query: 132 VPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETE 311
+P +++G+ MP +G+GT F S ++DVV+RAI+ GYRHFDTA+VY+TE
Sbjct: 1 MPEAALSSGKPMPRVGMGT-ASFPLGATDPST---VKDVVLRAIEAGYRHFDTAAVYQTE 56
Query: 312 QEIGEAVKMKVEEGVV-KREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMH 488
+G+AV V G+V R++++IT+KLW V ++ +L+K+ ++Y+DLYL+H
Sbjct: 57 AILGDAVAEAVRAGLVASRDELYITSKLWVAHAHPGHVLPSLRRALRKMQMEYLDLYLIH 116
Query: 489 WPIGL-------NADYSHSDVDFME---TWRGLEDAQRMGIVKGIGLSNFNKQQLERVLK 638
+P+ + + YS D+ M+ W+ +E+ QR+G+ K IG+SNF+ ++LE +L
Sbjct: 117 FPVSMRLAEDPESMTYSKDDLVMMDMEGVWKEMEECQRLGLTKAIGVSNFSCKKLETLLS 176
Query: 639 EGTIKPDA 662
TI P A
Sbjct: 177 FATISPAA 184
>UniRef50_A2R6Z3 Cluster: Catalytic activity: an alcohol + NADP(+)
<=> an aldehyde + NADPH; n=9; Pezizomycotina|Rep:
Catalytic activity: an alcohol + NADP(+) <=> an aldehyde
+ NADPH - Aspergillus niger
Length = 345
Score = 137 bits (331), Expect = 3e-31
Identities = 72/186 (38%), Positives = 106/186 (56%), Gaps = 13/186 (6%)
Frame = +3
Query: 138 SLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 317
+ K+N G DMPA+GLGT+ +SK ++RD V+ A+ GYRH D A+VY EQE
Sbjct: 6 TFKLNTGYDMPAVGLGTW---------QSKKDEVRDAVIAALKCGYRHIDAAAVYGNEQE 56
Query: 318 IGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 497
+G+ +++ V RE+IF+T+KLWNT H V +A++ SL L DY+DLYL+HWP+
Sbjct: 57 VGDGMRLSG----VPREEIFLTSKLWNTHHHPENVEEAVDKSLADLQTDYLDLYLIHWPV 112
Query: 498 GLNADYSH-------------SDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLK 638
+ DV +TW +E G V+ IG+SNF ++++E +LK
Sbjct: 113 AFRYSTTTIQPVNEQTGLIDVVDVPIKDTWAAMEKLVEKGKVRSIGVSNFTREKIEELLK 172
Query: 639 EGTIKP 656
I P
Sbjct: 173 TAKITP 178
>UniRef50_UPI0000498F1F Cluster: oxidoreductase, aldo/keto reductase
family; n=2; Entamoeba histolytica HM-1:IMSS|Rep:
oxidoreductase, aldo/keto reductase family - Entamoeba
histolytica HM-1:IMSS
Length = 305
Score = 136 bits (329), Expect = 4e-31
Identities = 70/173 (40%), Positives = 105/173 (60%), Gaps = 3/173 (1%)
Frame = +3
Query: 147 MNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGE 326
+NNG +P +GLGT++ NG V V AI GYRH D A Y E+E+G+
Sbjct: 7 LNNGYKIPKLGLGTWMS--ANGEVGK-------AVEIAIKNGYRHIDCAKAYGNEKEVGD 57
Query: 327 AVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLN 506
+K + +G VKRE++F+TTKLW+T + +V A +SLKKL L+Y+DLY++H P+ +
Sbjct: 58 GIKSAIAKGYVKREELFVTTKLWSTDKHKEDVRPACLESLKKLQLEYLDLYIIHIPLTAD 117
Query: 507 ---ADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
+++ + ETWR +E G+VK IG+SNFN ++LE +L I+P
Sbjct: 118 KKTGEFTEEIIPIEETWREMEKLVEEGLVKSIGVSNFNIKKLEELLAIAKIQP 170
>UniRef50_Q01J82 Cluster: OSIGBa0152K17.5 protein; n=28;
Magnoliophyta|Rep: OSIGBa0152K17.5 protein - Oryza
sativa (Rice)
Length = 323
Score = 136 bits (329), Expect = 4e-31
Identities = 73/190 (38%), Positives = 112/190 (58%), Gaps = 9/190 (4%)
Frame = +3
Query: 114 LASTMEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTA 293
+A+ EV +L+ GR MPA+G+GT + S + + R + A++VG+RHFDTA
Sbjct: 1 MAAVPEV-ALRHGAGRPMPAVGVGT-----ADSAATSPETK-RGAALAALEVGFRHFDTA 53
Query: 294 SVYETEQEIGEAVKMKVEEGVV-KREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYI 470
++Y TE +GEA+ G+V RE++F+TTKLW TQ V ++ +SL+ L ++Y+
Sbjct: 54 ALYGTEAPLGEAIAEATRRGLVASREEVFVTTKLWCTQCHPGLVLPSLRESLRNLQMEYV 113
Query: 471 DLYLMHWPIGLN-----ADYSHSDV---DFMETWRGLEDAQRMGIVKGIGLSNFNKQQLE 626
DLYL+HWPI + D DF WR +E+ R+G+ K IG+SNF + L+
Sbjct: 114 DLYLVHWPISVKPGPPMLPVKREDAVPFDFEGVWRAMEECHRLGLAKAIGVSNFTTKHLD 173
Query: 627 RVLKEGTIKP 656
++L TI P
Sbjct: 174 KLLAVATIPP 183
>UniRef50_Q2S340 Cluster: Aldehyde reductase; n=10; Bacteria|Rep:
Aldehyde reductase - Salinibacter ruber (strain DSM
13855)
Length = 321
Score = 136 bits (328), Expect = 6e-31
Identities = 67/184 (36%), Positives = 107/184 (58%), Gaps = 10/184 (5%)
Frame = +3
Query: 138 SLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 317
S+ NG +MP IGLGT+ KS ++ + V A++ GYRH D A +Y+ E E
Sbjct: 3 SISFENGDEMPMIGLGTW---------KSPPGEVYEAVTTALEAGYRHVDCAPIYKNETE 53
Query: 318 IGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 497
+G A+ + G ++R+D+++T+KLWN H +V A+ +L L LD +DLYL+HWP+
Sbjct: 54 VGAALSDSFDAGGIRRDDVWVTSKLWNNAHHPDDVRPALEQTLSDLRLDALDLYLIHWPV 113
Query: 498 GL--NADYSHSDVDFM--------ETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGT 647
L D+ S DF+ ETW +E ++ G+V+ IG+SNF+ L+ +L G
Sbjct: 114 ALQPEVDFPESPDDFVSPEAVPLTETWAAMEALKKDGLVRHIGVSNFSVPNLQMILDAGE 173
Query: 648 IKPD 659
++P+
Sbjct: 174 VRPE 177
>UniRef50_P26690 Cluster: NAD(P)H-dependent 6'-deoxychalcone
synthase; n=3; Papilionoideae|Rep: NAD(P)H-dependent
6'-deoxychalcone synthase - Glycine max (Soybean)
Length = 315
Score = 135 bits (326), Expect = 1e-30
Identities = 68/192 (35%), Positives = 115/192 (59%), Gaps = 11/192 (5%)
Frame = +3
Query: 114 LASTMEVPSLKMNNG---RDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHF 284
+A+ +E+P++ N + MP +G+G+ F + K ++ ++ A+ GYRHF
Sbjct: 1 MAAAIEIPTIVFPNSSAQQRMPVVGMGSAPDF-------TCKKDTKEAIIEAVKQGYRHF 53
Query: 285 DTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLD 464
DTA+ Y +EQ +GEA+K + G+V R+D+F+T+KLW T++ V A+ SLK L L+
Sbjct: 54 DTAAAYGSEQALGEALKEAIHLGLVSRQDLFVTSKLWVTENHPHLVLPALRKSLKTLQLE 113
Query: 465 YIDLYLMHWPIG-----LNADYSHSDV---DFMETWRGLEDAQRMGIVKGIGLSNFNKQQ 620
Y+DLYL+HWP+ + D+ D W +E+ Q++G+ K IG+SNF+ ++
Sbjct: 114 YLDLYLIHWPLSSQPGKFSFPIEVEDLLPFDVKGVWESMEECQKLGLTKAIGVSNFSVKK 173
Query: 621 LERVLKEGTIKP 656
L+ +L TI+P
Sbjct: 174 LQNLLSVATIRP 185
>UniRef50_Q6TY50 Cluster: Reductase 2; n=10; Magnoliophyta|Rep:
Reductase 2 - Hydrangea macrophylla (Bigleaf hydrangea)
Length = 321
Score = 133 bits (321), Expect = 4e-30
Identities = 68/185 (36%), Positives = 112/185 (60%), Gaps = 10/185 (5%)
Frame = +3
Query: 132 VPSLKMNNG-RDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYET 308
+P + +++G R MP +GLGT + + +R V A+ +GYRHFDTA++Y +
Sbjct: 5 IPEVPLSSGGRKMPVLGLGTAADPPVD------PETVRKAVTEALKLGYRHFDTAALYNS 58
Query: 309 EQEIGEAVKMKVEEGVVK-REDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLM 485
EQ +G+A+ + EG++K R+++FIT+KLW + R V A+ +LK L L+YID+YL+
Sbjct: 59 EQPLGDAIAEALGEGLIKSRDELFITSKLWCSDAHRENVEPALQKTLKNLKLEYIDMYLI 118
Query: 486 HWPIGL---NADYSHSDVDFME-----TWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKE 641
HWP+ N +Y DF++ W +E+ Q++G+ K IG+SNF+ ++L VL
Sbjct: 119 HWPVSSKPGNYEYPIKKEDFLQMDYKSVWEAMEECQKLGLTKAIGVSNFSCKKLSDVLAN 178
Query: 642 GTIKP 656
+ P
Sbjct: 179 AKVPP 183
>UniRef50_A5KSS3 Cluster: Aldehyde reductase; n=1; candidate
division TM7 genomosp. GTL1|Rep: Aldehyde reductase -
candidate division TM7 genomosp. GTL1
Length = 299
Score = 132 bits (318), Expect = 1e-29
Identities = 68/183 (37%), Positives = 102/183 (55%), Gaps = 11/183 (6%)
Frame = +3
Query: 141 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 320
L + N + +P +G GT+ + D+V AI GYRH D A +Y E+E+
Sbjct: 4 LTLRNKQTLPLLGYGTW---------ELPTGTTADLVETAIKAGYRHIDCAMIYGNEKEV 54
Query: 321 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI- 497
GE ++ +++GVVKRED+F+T+KLWNT H + +V A +L LGLDY+DLYL+HW +
Sbjct: 55 GEGIRRTIDQGVVKREDLFVTSKLWNTDHAQVDVGVACRKTLNDLGLDYLDLYLIHWGVA 114
Query: 498 ---GLNADYSHSD-------VDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGT 647
G N + D + ETW+ +E+ G+VK +G++NF L +L
Sbjct: 115 FEHGDNLEPLDDDGVAKFSFISMKETWQAMEELVEQGLVKSMGVANFTAPMLLDLLSYAK 174
Query: 648 IKP 656
IKP
Sbjct: 175 IKP 177
>UniRef50_Q41E86 Cluster: 2,5-didehydrogluconate reductase; n=2;
Bacteria|Rep: 2,5-didehydrogluconate reductase -
Exiguobacterium sibiricum 255-15
Length = 274
Score = 131 bits (317), Expect = 1e-29
Identities = 71/170 (41%), Positives = 99/170 (58%)
Frame = +3
Query: 147 MNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGE 326
+NNG MP +G G + K ++++ + V A+ VGYR DTA +YE E +G
Sbjct: 6 LNNGLVMPQLGYGVF---------KVPEQEVYEAVREALRVGYRSIDTAMIYENEAGVGR 56
Query: 327 AVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLN 506
A+K + + REDIF+TTK+WN A SL+KLG+DY+DLYL+HWP+
Sbjct: 57 ALK----DSGIPREDIFLTTKVWNKDQGYERTLAAFETSLQKLGVDYVDLYLIHWPM--- 109
Query: 507 ADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
D+ +M+TWR LE R G K IG+SNF+ L RVL+EGT+ P
Sbjct: 110 ---PDEDL-YMDTWRALEQLYRDGKAKAIGVSNFHIPHLTRVLEEGTVVP 155
>UniRef50_Q8SSK6 Cluster: ALDOSE REDUCTASE; n=1; Encephalitozoon
cuniculi|Rep: ALDOSE REDUCTASE - Encephalitozoon
cuniculi
Length = 301
Score = 131 bits (317), Expect = 1e-29
Identities = 71/185 (38%), Positives = 103/185 (55%), Gaps = 11/185 (5%)
Frame = +3
Query: 144 KMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIG 323
K+NNG+++P +GLGT+ G + V L + A+ +GYRH DTA +Y E+ IG
Sbjct: 7 KLNNGKEIPTVGLGTW-GMEDEAV-------LEGAIRNALSLGYRHIDTAFIYGNEKMIG 58
Query: 324 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI-- 497
+K +EGVV+R+D+FIT+KLWNT H E + SL L +DY+DLYL+HWP+
Sbjct: 59 NILKKLFDEGVVQRKDLFITSKLWNTFHGCPE--DGLRRSLNDLQMDYVDLYLIHWPVTF 116
Query: 498 ---------GLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTI 650
Y+ D + W+ +E +G+ K IG+SNF K E++L I
Sbjct: 117 DPAPDGTVESCGKKYNVGKFDAVGVWKKMEALVDLGLAKSIGISNFGKANTEKILGTCRI 176
Query: 651 KPDAI 665
P AI
Sbjct: 177 CPAAI 181
>UniRef50_Q2V420 Cluster: Uncharacterized protein At2g37770.1; n=1;
Arabidopsis thaliana|Rep: Uncharacterized protein
At2g37770.1 - Arabidopsis thaliana (Mouse-ear cress)
Length = 283
Score = 131 bits (316), Expect = 2e-29
Identities = 70/178 (39%), Positives = 104/178 (58%), Gaps = 7/178 (3%)
Frame = +3
Query: 144 KMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIG 323
K+N G P++GLGT+ G+V D V A+ +GYRH D A +Y E+EIG
Sbjct: 9 KLNTGAKFPSVGLGTWQA--SPGLVG-------DAVAAAVKIGYRHIDCAQIYGNEKEIG 59
Query: 324 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP--- 494
+K E+ VVKRED+FIT+KLW T H +V +A+N +LK L L+Y+DLYL+HWP
Sbjct: 60 AVLKKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARI 119
Query: 495 ----IGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
+G+ + + VD TW+ +E G + IG+SNF+ ++L +L+ + P
Sbjct: 120 KKGSVGIKPE-NLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVPP 176
>UniRef50_Q0PGJ6 Cluster: Aldo-keto reductase; n=32;
Magnoliophyta|Rep: Aldo-keto reductase - Arabidopsis
thaliana (Mouse-ear cress)
Length = 315
Score = 131 bits (316), Expect = 2e-29
Identities = 70/178 (39%), Positives = 104/178 (58%), Gaps = 7/178 (3%)
Frame = +3
Query: 144 KMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIG 323
K+N G P++GLGT+ G+V D V A+ +GYRH D A +Y E+EIG
Sbjct: 9 KLNTGAKFPSVGLGTWQA--SPGLVG-------DAVAAAVKIGYRHIDCAQIYGNEKEIG 59
Query: 324 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP--- 494
+K E+ VVKRED+FIT+KLW T H +V +A+N +LK L L+Y+DLYL+HWP
Sbjct: 60 AVLKKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARI 119
Query: 495 ----IGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
+G+ + + VD TW+ +E G + IG+SNF+ ++L +L+ + P
Sbjct: 120 KKGSVGIKPE-NLLPVDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVPP 176
>UniRef50_Q968S3 Cluster: Aldoketoreductase-like protein; n=1;
Orconectes limosus|Rep: Aldoketoreductase-like protein -
Orconectes limosus (Spinycheek crayfish)
Length = 336
Score = 131 bits (316), Expect = 2e-29
Identities = 72/186 (38%), Positives = 110/186 (59%), Gaps = 10/186 (5%)
Frame = +3
Query: 129 EVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYET 308
++P++ +N+G +P +GLGT +NG K ++ + V+ A++ GYRHFD+A+ Y
Sbjct: 10 KIPTILLNSGSHIPVMGLGTG-SLGRNG--KMSEEAVTAVLETALECGYRHFDSAAYYGN 66
Query: 309 EQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMH 488
E IG+ ++ + EG VKRE++FITTKL +R +VA+ + SL L L Y+DLYL+H
Sbjct: 67 EAIIGQVLRRWISEGKVKREELFITTKLPTRGNREKDVARFLQKSLDNLRLPYVDLYLVH 126
Query: 489 WPIG--------LNADYSHSD--VDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLK 638
+P G L+AD D D WR +E G K IGLSNFN Q++R++K
Sbjct: 127 YPCGILDTDRERLSADEVTVDPTTDIHAIWRAMEAQLAAGKTKNIGLSNFNADQVQRIIK 186
Query: 639 EGTIKP 656
++P
Sbjct: 187 GCQVRP 192
>UniRef50_Q7G764 Cluster: Probable NAD(P)H-dependent oxidoreductase
1; n=32; Eukaryota|Rep: Probable NAD(P)H-dependent
oxidoreductase 1 - Oryza sativa subsp. japonica (Rice)
Length = 321
Score = 130 bits (314), Expect = 3e-29
Identities = 70/191 (36%), Positives = 113/191 (59%), Gaps = 10/191 (5%)
Frame = +3
Query: 114 LASTMEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTA 293
+A+ EVP+ ++ + MP +G+GT F S+D ++RAI++GYRHFDTA
Sbjct: 1 MATIPEVPASELI--QTMPRVGMGT-AAFP---FTSSEDTTA--AMLRAIELGYRHFDTA 52
Query: 294 SVYETEQEIGEAVKMKVEEGVV-KREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYI 470
+Y TE +GEAV V G++ R D+F+T+K+W + V A ++L+ LG+DY+
Sbjct: 53 RIYATEGCVGEAVAEAVRRGLIASRADVFVTSKIWCSDLHAGRVVPAARETLRNLGMDYV 112
Query: 471 DLYLMHWPIGL---NADYSH------SDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQL 623
DL L+HWP+ L N D+ D WRG+E+ R+G+ + IG+SNF+ ++L
Sbjct: 113 DLLLVHWPVSLTPGNYDFPFPKEVILPSFDMEGVWRGMEECHRLGLARAIGVSNFSAKKL 172
Query: 624 ERVLKEGTIKP 656
E++L ++P
Sbjct: 173 EQLLSLAAVRP 183
>UniRef50_Q235V6 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=2; Tetrahymena thermophila SB210|Rep:
Oxidoreductase, aldo/keto reductase family protein -
Tetrahymena thermophila SB210
Length = 332
Score = 129 bits (311), Expect = 7e-29
Identities = 68/174 (39%), Positives = 107/174 (61%), Gaps = 1/174 (0%)
Frame = +3
Query: 138 SLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 317
S K+NNG+ MP +GLGTYL + SK+ ++ +++ A+D GYRH DTA Y+ E
Sbjct: 7 SSKLNNGQIMPLVGLGTYL-------LNSKE-EMTNLLRTALDAGYRHIDTAVNYQNEAM 58
Query: 318 IGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 497
IGE++K +EG R+D+FI +K++ ++ + +++ SLK+L LDY+DLY +H+P+
Sbjct: 59 IGESLKTIFKEGKYSRKDLFIVSKVF--PNKGINMLESVKKSLKELQLDYVDLYYLHFPL 116
Query: 498 G-LNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
G L+ + W LE+A R+G+ K IG+SNFN L +L +KP
Sbjct: 117 GFLSEKEEFVHLPVHVAWAQLEEAHRLGLAKSIGVSNFNVMALADLLSYAKVKP 170
>UniRef50_Q5BKE9 Cluster: LOC594893 protein; n=5; Xenopus
tropicalis|Rep: LOC594893 protein - Xenopus tropicalis
(Western clawed frog) (Silurana tropicalis)
Length = 345
Score = 128 bits (310), Expect = 9e-29
Identities = 71/198 (35%), Positives = 112/198 (56%), Gaps = 26/198 (13%)
Frame = +3
Query: 138 SLKMNNGRDMPAIGLGTYLGFD---------------QNGVVKSKDKQLRDVVMRAIDVG 272
S+++++GR MP + GT+ F ++G KS +R A+D+G
Sbjct: 8 SIQLHDGRWMPVVAFGTFYPFTFPGDSQANPGHCAGTKHGTEKSFIDDVRVATKMALDLG 67
Query: 273 YRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKK 452
YRH D A +Y +E +G+A + K +G +KRED+F T+KLWNT H+ V A+ +L
Sbjct: 68 YRHVDGAFLYSSETGVGQAFREKFADGTLKREDLFYTSKLWNTFHQPHLVRPALEKTLSF 127
Query: 453 LGLDYIDLYLMHWPIGL---------NAD--YSHSDVDFMETWRGLEDAQRMGIVKGIGL 599
L +DY+DLYL+H P+ N D + D ++TW+ LE+ + G+VK IG+
Sbjct: 128 LQMDYVDLYLIHMPMSFKPAEELFPKNEDGTCAFDQPDLLQTWQALEECRDAGLVKSIGV 187
Query: 600 SNFNKQQLERVLKEGTIK 653
SNFN++QLE +L + +K
Sbjct: 188 SNFNRRQLEMILNKPGLK 205
>UniRef50_A7CWF9 Cluster: Aldehyde reductase; n=2; Bacteria|Rep:
Aldehyde reductase - Opitutaceae bacterium TAV2
Length = 347
Score = 128 bits (310), Expect = 9e-29
Identities = 70/189 (37%), Positives = 107/189 (56%), Gaps = 13/189 (6%)
Frame = +3
Query: 129 EVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYET 308
++P + +G MPAIG+GT+ G D + ++ V A ++GYRHFD A+VY
Sbjct: 15 KIPQRTLASGARMPAIGMGTF-GSDH-----AAPGEVAASVYAAAELGYRHFDCAAVYSN 68
Query: 309 EQEIGEAVKMKVEEGV-VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLM 485
E+EIG + + ++RED++IT+KLWN +H +V A SL+ LGLDY+DLYL+
Sbjct: 69 EREIGATFRRILTSNTGIRREDLWITSKLWNDKHAEADVIPAFEKSLRDLGLDYLDLYLI 128
Query: 486 HWPI------GLNADYSHSD------VDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLER 629
HWP G + D +FM+TWR LE G+V+ IG SN +L+
Sbjct: 129 HWPFPNFHPPGCDVSSRSPDARPYIHAEFMKTWRQLETLHDRGLVRHIGTSNMTIAKLQL 188
Query: 630 VLKEGTIKP 656
+L++ ++P
Sbjct: 189 LLRDARVRP 197
>UniRef50_A4RQH8 Cluster: Predicted protein; n=2; Ostreococcus|Rep:
Predicted protein - Ostreococcus lucimarinus CCE9901
Length = 337
Score = 128 bits (309), Expect = 1e-28
Identities = 63/160 (39%), Positives = 93/160 (58%), Gaps = 3/160 (1%)
Frame = +3
Query: 153 NGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAV 332
NG +P +GLGT+ K++ ++RD V A+ GY H D A+ Y E E+GEA+
Sbjct: 12 NGLRIPRVGLGTW---------KARPNEVRDAVRDALGAGYAHVDCAAAYANESEVGEAL 62
Query: 333 KMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNAD 512
+ E G KRED+F+T+KLWN + R +V +A+ +L LG+ Y+DLYL+HWP+
Sbjct: 63 REAFERGDAKREDVFVTSKLWNDRRRPRDVREALMTTLNDLGVGYLDLYLIHWPVAWKRG 122
Query: 513 ---YSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQL 623
++ E W LE G+V+ IG+SNFN+ QL
Sbjct: 123 TVLQPDAEASIAECWSELERCVADGLVRHIGVSNFNEAQL 162
>UniRef50_Q88SL1 Cluster: Oxidoreductase; n=51; Lactobacillales|Rep:
Oxidoreductase - Lactobacillus plantarum
Length = 286
Score = 127 bits (307), Expect = 2e-28
Identities = 69/183 (37%), Positives = 104/183 (56%), Gaps = 3/183 (1%)
Frame = +3
Query: 117 ASTMEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLR-DVVMRAIDVGYRHFDTA 293
A T + +NNG +P +G GT+ ++ D Q+ D V+ A+ GYRH DTA
Sbjct: 3 ALTKLTDTYTLNNGTKIPIVGFGTW---------QTPDGQVAYDSVLAALKAGYRHIDTA 53
Query: 294 SVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYID 473
+ Y E+ +G+A+ + GV RED+F+TTKLWN H +A++ SL KLGLDY+D
Sbjct: 54 AAYGNEESVGKAI---ADSGVA-REDLFVTTKLWNADHGYDAAKKALDTSLAKLGLDYVD 109
Query: 474 LYLMHW--PIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGT 647
LYL+HW P + ++ + D TWR +E+A + IG+SNF + L+ +LK
Sbjct: 110 LYLIHWPNPAAMRDNWEQLNAD---TWRAMEEAYTARKARAIGVSNFRPKHLDALLKTAK 166
Query: 648 IKP 656
+ P
Sbjct: 167 VVP 169
>UniRef50_Q5FK98 Cluster: Oxidoreductase; n=8; Lactobacillales|Rep:
Oxidoreductase - Lactobacillus acidophilus
Length = 285
Score = 127 bits (307), Expect = 2e-28
Identities = 66/170 (38%), Positives = 102/170 (60%)
Frame = +3
Query: 147 MNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGE 326
+NNG +P IG GT+ D G V + V+ A++ GYRH DTAS Y E +G
Sbjct: 12 LNNGVKIPIIGFGTWQTPD--GEVAEES------VLAALNCGYRHIDTASAYGNEDSVGR 63
Query: 327 AVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLN 506
A+ ++ + R ++FITTKLWN+ H + +AI+ SL L LDY+D+YL+HWP +
Sbjct: 64 AI----QKSGINRHELFITTKLWNSDHGYEKTKKAIDQSLLDLKLDYLDMYLIHWPNPSS 119
Query: 507 ADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
++++ E+WR +E+A R G ++ IG+SNF K L+ +++ IKP
Sbjct: 120 MRDHWAEIN-AESWRAMEEAVRAGKIRAIGVSNFRKHHLDALMETAEIKP 168
>UniRef50_Q55FL3 Cluster: Aldo-keto reductase; n=2; Dictyostelium
discoideum AX4|Rep: Aldo-keto reductase - Dictyostelium
discoideum AX4
Length = 321
Score = 127 bits (307), Expect = 2e-28
Identities = 73/189 (38%), Positives = 107/189 (56%), Gaps = 16/189 (8%)
Frame = +3
Query: 138 SLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 317
+ K+N+G +P+IGLGTY + +N ++ D + A+ GYRH D A+ Y E+
Sbjct: 16 NFKLNDGNQIPSIGLGTY--YSEN------PGEVGDAINNALKNGYRHIDGAAFYGNEKV 67
Query: 318 IGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 497
IG ++K +EG +KREDIF T+KLWN+ H V + +++ LG+ Y+DLYL+HWPI
Sbjct: 68 IGNSLKEIFKEGEIKREDIFYTSKLWNSCHNSNLVVKHCVKTIEDLGIGYLDLYLIHWPI 127
Query: 498 --------GL--------NADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLER 629
GL N + + V ETW+ +E +G+VK IG+SNFN Q L
Sbjct: 128 AFENSNPLGLTIEPLRDQNGNPIIAPVSIRETWQEMEKLVELGLVKSIGVSNFNVQNLVD 187
Query: 630 VLKEGTIKP 656
+L IKP
Sbjct: 188 LLTYAKIKP 196
>UniRef50_Q7ZWA4 Cluster: Zgc:56622; n=6; cellular organisms|Rep:
Zgc:56622 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 289
Score = 127 bits (306), Expect = 3e-28
Identities = 57/144 (39%), Positives = 89/144 (61%), Gaps = 11/144 (7%)
Frame = +3
Query: 258 AIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAIN 437
AI GYRH DTA Y E ++G A++ K+++G+++R+D+FI +KLW T H ++ N
Sbjct: 9 AIAAGYRHIDTAFCYRNEVDVGMAIQNKIQQGIIRRQDMFIVSKLWGTHHAPEDIPVCFN 68
Query: 438 DSLKKLGLDYIDLYLMHWPIGL-----------NADYSHSDVDFMETWRGLEDAQRMGIV 584
SL L LDY+D YL+H+P+GL + +D+D+++ WRG+E + G V
Sbjct: 69 KSLSDLQLDYLDQYLVHFPVGLKKVGDELFPERDGKILTTDIDYVDVWRGMEALKATGKV 128
Query: 585 KGIGLSNFNKQQLERVLKEGTIKP 656
K IG+SNF +Q++R+L I P
Sbjct: 129 KSIGVSNFTMEQIDRLLSVAKIPP 152
>UniRef50_P28475 Cluster: NADP-dependent D-sorbitol-6-phosphate
dehydrogenase; n=71; Magnoliophyta|Rep: NADP-dependent
D-sorbitol-6-phosphate dehydrogenase - Malus domestica
(Apple) (Malus sylvestris)
Length = 310
Score = 127 bits (306), Expect = 3e-28
Identities = 69/188 (36%), Positives = 110/188 (58%), Gaps = 15/188 (7%)
Frame = +3
Query: 138 SLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 317
++ +++G +MP IGLG + + + +L++V++ AI +GYRHFD A+ Y++E +
Sbjct: 3 TVTLSSGYEMPVIGLGLW---------RLEKDELKEVILNAIKIGYRHFDCAAHYKSEAD 53
Query: 318 IGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP- 494
+GEA+ + G+VKRE++FITTK+WN+ H V +A +SL+KL +DY+DLYL+H+P
Sbjct: 54 VGEALAEAFKTGLVKREELFITTKIWNSDH--GHVVEACKNSLEKLQIDYLDLYLVHYPM 111
Query: 495 ------IGLNADYSHSD--------VDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERV 632
IG A D + +TW G+E +G+V+ IGLSN+
Sbjct: 112 PTKHNAIGKTASLLGEDKVLDIDVTISLQQTWEGMEKTVSLGLVRSIGLSNYELFLTRDC 171
Query: 633 LKEGTIKP 656
L IKP
Sbjct: 172 LAYSKIKP 179
>UniRef50_Q7N0E4 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=2; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase
A - Photorhabdus luminescens subsp. laumondii
Length = 292
Score = 126 bits (305), Expect = 4e-28
Identities = 63/174 (36%), Positives = 105/174 (60%)
Frame = +3
Query: 135 PSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQ 314
P +++ +G MP +GLG++ S D+Q+ + + A+D+GYR DTA++Y E+
Sbjct: 5 PIIRLADGNHMPQLGLGSWA---------SDDQQIAETIHAALDIGYRAIDTAAIYNNEK 55
Query: 315 EIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 494
+G A+ +E + REDIF+TTKLWN +H + A+ +SL+KL LDY+DLYL+HWP
Sbjct: 56 GVGNAL----QETDIPREDIFVTTKLWNDRH--LDARAALTESLEKLQLDYVDLYLIHWP 109
Query: 495 IGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
Y + W+ L + Q+ G+++ IG+SNF + ++R++ E + P
Sbjct: 110 APPQDQY-------VGAWQQLIELQKEGLIRSIGVSNFQPEHIQRLINETGVHP 156
>UniRef50_Q9FJK0 Cluster: Aldose reductase-like protein; n=3; core
eudicotyledons|Rep: Aldose reductase-like protein -
Arabidopsis thaliana (Mouse-ear cress)
Length = 316
Score = 126 bits (305), Expect = 4e-28
Identities = 64/181 (35%), Positives = 105/181 (58%), Gaps = 10/181 (5%)
Frame = +3
Query: 144 KMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLR-DVVMRAIDVGYRHFDTASVYETEQEI 320
++ G +P +G+GTY KD++ V +AI +GYRHFDTA +Y +E+ +
Sbjct: 7 RLRCGETIPLLGMGTYC--------PQKDRESTISAVHQAIKIGYRHFDTAKIYGSEEAL 58
Query: 321 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 500
G A+ + G V+R+D+F+T+KLW++ H + A+ +LK +GLDY+D YL+HWPI
Sbjct: 59 GTALGQAISYGTVQRDDLFVTSKLWSSDHH--DPISALIQTLKTMGLDYLDNYLVHWPIK 116
Query: 501 L---------NADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIK 653
L D D+ ETW+G+E MG+ + IG+SNF+ +++ +L ++
Sbjct: 117 LKPGVSEPIPKEDEFEKDLGIEETWQGMERCLEMGLCRSIGVSNFSSKKIFDLLDFASVS 176
Query: 654 P 656
P
Sbjct: 177 P 177
>UniRef50_Q5HR31 Cluster: Oxidoreductase, aldo/keto reductase
family; n=3; Staphylococcus|Rep: Oxidoreductase,
aldo/keto reductase family - Staphylococcus epidermidis
(strain ATCC 35984 / RP62A)
Length = 279
Score = 126 bits (303), Expect = 6e-28
Identities = 68/170 (40%), Positives = 98/170 (57%)
Frame = +3
Query: 147 MNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGE 326
+NNG MPA+GLG Y K D+Q+ +VV A+D GYR FDTA Y E+ +G
Sbjct: 8 LNNGYPMPAVGLGVY---------KIADEQMEEVVRTALDAGYRAFDTAYFYGNEKALGS 58
Query: 327 AVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLN 506
A+K V+R+++FIT+KLWN + + N SL LGLDY+DL+L+HWP
Sbjct: 59 ALK----HSNVERDELFITSKLWNDYQGYDQTIEYFNKSLDNLGLDYLDLFLIHWP---- 110
Query: 507 ADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
+D ++E+++ LE G +K IG+ NF LE+++KE I P
Sbjct: 111 ---CENDQLYIESYKALEHLYEEGKIKAIGVCNFKIHHLEKLMKETKITP 157
>UniRef50_Q6CFG7 Cluster: Yarrowia lipolytica chromosome B of strain
CLIB122 of Yarrowia lipolytica; n=9; Ascomycota|Rep:
Yarrowia lipolytica chromosome B of strain CLIB122 of
Yarrowia lipolytica - Yarrowia lipolytica (Candida
lipolytica)
Length = 337
Score = 126 bits (303), Expect = 6e-28
Identities = 76/193 (39%), Positives = 111/193 (57%), Gaps = 15/193 (7%)
Frame = +3
Query: 123 TMEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAI-DVGYRHFDTASV 299
TM +NNG+ +PAIGLGT+ KS +++ V A+ + GYRH DTA
Sbjct: 28 TMTSLDFTLNNGKTIPAIGLGTW---------KSTTEEVAGAVECALTEGGYRHIDTAFN 78
Query: 300 YETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLY 479
Y E +G +K +E+GV KREDIF+TTK+W T H R E + ++ SL++LGLDY+D+
Sbjct: 79 YRNEDAVGLGIKRAMEKGV-KREDIFVTTKIWVTYHDRVE--ENLDMSLERLGLDYVDML 135
Query: 480 LMHWPIGLNADYSHS----------DVDFM----ETWRGLEDAQRMGIVKGIGLSNFNKQ 617
L+HWP+ LN + + D+D +TW+ +E + G K IG+SNF+
Sbjct: 136 LIHWPVPLNPNGNDPVYPLRPDGSRDIDESGSQPKTWKQMEAVLKTGKTKSIGVSNFSIP 195
Query: 618 QLERVLKEGTIKP 656
LE +LKE + P
Sbjct: 196 YLEELLKEAEVVP 208
>UniRef50_Q4P4P1 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 322
Score = 126 bits (303), Expect = 6e-28
Identities = 67/181 (37%), Positives = 102/181 (56%)
Frame = +3
Query: 114 LASTMEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTA 293
++ + +K+NNG+++P + LG Y D + A D GYRH D+A
Sbjct: 10 ISGNISTQRIKLNNGQEIPQVALGVYKA--------PNDGSTENACKWAFDAGYRHIDSA 61
Query: 294 SVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYID 473
+ Y E+ +G A+ +E V R +IFIT+KLW+ H + A AI DSLKKL +DY+D
Sbjct: 62 ARYMNEESVGRALAEWTKENNVPRSEIFITSKLWDADH--DKAAAAIEDSLKKLNVDYMD 119
Query: 474 LYLMHWPIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIK 653
+YLMH P + A+ +E W+ LE+A G +K IG+SNF+ ++L+ +L IK
Sbjct: 120 MYLMHSPGTMGAEKR------LEAWKALEEAVDAGKIKTIGVSNFDVEELDHLLANCRIK 173
Query: 654 P 656
P
Sbjct: 174 P 174
>UniRef50_Q9U2J5 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 339
Score = 125 bits (302), Expect = 8e-28
Identities = 67/189 (35%), Positives = 110/189 (58%), Gaps = 16/189 (8%)
Frame = +3
Query: 138 SLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 317
++ +N+G +MP IG GT+ +N + ++RD A++ GYRH D+A ++ ++E
Sbjct: 6 TVTLNSGYEMPVIGYGTWQ-LPKNLAAE----RVRD----ALEAGYRHIDSALSFKNQEE 56
Query: 318 IGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 497
+ +K + V+RE++F+++K+WNT H R Q I++ L+ Y+DL ++HWP
Sbjct: 57 VAAGIKDWCKIRKVRREELFLSSKIWNTYHSRNRCMQQIDEMLEIFETTYMDLIVIHWPF 116
Query: 498 ----------------GLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLER 629
G N +SDVD++ETW+ LEDA R G ++ IGL+NFN Q+E+
Sbjct: 117 GWAEDEPPGERGLWPRGANGKMRYSDVDYLETWKALEDAHRSGKIRSIGLANFNIGQVEQ 176
Query: 630 VLKEGTIKP 656
V +G IKP
Sbjct: 177 VWTKGLIKP 185
>UniRef50_UPI0000E45E29 Cluster: PREDICTED: similar to aldose
reductase; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to aldose reductase -
Strongylocentrotus purpuratus
Length = 274
Score = 125 bits (301), Expect = 1e-27
Identities = 65/145 (44%), Positives = 87/145 (60%)
Frame = +3
Query: 222 SKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNT 401
SK Q+ V AID GYRH D A VY E E+G +K K + VVKREDIFIT+KLWN
Sbjct: 7 SKPGQVEAAVKAAIDCGYRHIDCAHVYGNEAEVGAGLKEKFDANVVKREDIFITSKLWNN 66
Query: 402 QHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQRMGI 581
+H +V QA + +LK L L Y+DLYLMHWP+ ++ +E G
Sbjct: 67 KHHPDDVEQACDITLKNLQLSYVDLYLMHWPM---------------AYQAMEKLVTSGK 111
Query: 582 VKGIGLSNFNKQQLERVLKEGTIKP 656
K IGLSNF+ + ++RV+++ TI+P
Sbjct: 112 CKAIGLSNFSMKMMKRVIEKATIQP 136
>UniRef50_Q6NII7 Cluster: Putative oxidoreductase; n=2;
Corynebacterium|Rep: Putative oxidoreductase -
Corynebacterium diphtheriae
Length = 290
Score = 125 bits (301), Expect = 1e-27
Identities = 64/175 (36%), Positives = 101/175 (57%)
Frame = +3
Query: 132 VPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETE 311
+P++ +N+G +MPAIG GTY K +++ V AI+VGYRH DTAS+Y+ E
Sbjct: 11 IPTITLNDGTEMPAIGFGTY---------KLREQDAYRAVRSAIEVGYRHIDTASLYKNE 61
Query: 312 QEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHW 491
+E+G AV + G V R+++FITTK+WN H ++ +SL +LGLDYID ++HW
Sbjct: 62 EEVGRAVADAITAGEVARDELFITTKVWNDMHGDQLTQRSFQESLHRLGLDYIDCCMVHW 121
Query: 492 PIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
P Y +E++ L Q +G ++ + ++NF + L ++ E I P
Sbjct: 122 PWPQKGLY-------VESFAALAKIQGLGQLQSVAVANFYPEVLREIVAETGIAP 169
>UniRef50_Q7ZA52 Cluster: Aldose reductase; n=6; Pezizomycotina|Rep:
Aldose reductase - Magnaporthe grisea (Rice blast
fungus) (Pyricularia grisea)
Length = 312
Score = 125 bits (301), Expect = 1e-27
Identities = 70/184 (38%), Positives = 106/184 (57%), Gaps = 14/184 (7%)
Frame = +3
Query: 147 MNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGE 326
+N G +PA GLGT+ G GV+K + V+ AI GYR D A VY E+E+G+
Sbjct: 8 LNTGAKIPAFGLGTWQG--DKGVIK-------EAVLTAIKSGYRLIDGAYVYGNEEEVGQ 58
Query: 327 AVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLN 506
++ + G+VKRED+F+ +K W T R E+ ++ SLK LGLDY+DLYL+HWPI +N
Sbjct: 59 GIREAISSGIVKREDLFVVSKCWATYTTRCEL--GLDQSLKLLGLDYVDLYLVHWPILMN 116
Query: 507 ADYS------HSD--------VDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEG 644
+ + H+D + ++TW+ +E G K +G+SN++K LE++L
Sbjct: 117 PEGNDEKFPKHADGSRDIIHTHNHVDTWKLMEKLPATGKTKAVGVSNYSKAWLEQLLPHA 176
Query: 645 TIKP 656
T P
Sbjct: 177 TTVP 180
>UniRef50_Q6C2L0 Cluster: Yarrowia lipolytica chromosome F of strain
CLIB122 of Yarrowia lipolytica; n=3; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome F of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 324
Score = 125 bits (301), Expect = 1e-27
Identities = 70/185 (37%), Positives = 112/185 (60%), Gaps = 17/185 (9%)
Frame = +3
Query: 138 SLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 317
S K+N+G +PA+GLGT + D + +VV AI GYRH DTA +Y +E +
Sbjct: 6 SFKLNDGHSIPALGLGT-----------ASDGNVEEVVYAAIKNGYRHIDTAFIYGSEVD 54
Query: 318 IGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 497
+G+ +K ++E +VKRE++F+TTK+W T + R V+++++ SLK L LDY+DL L+HWP+
Sbjct: 55 VGKGIKRAIDEELVKRENLFVTTKVWPTFYNR--VSESLDISLKDLSLDYVDLLLVHWPV 112
Query: 498 GLNAD-----------------YSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLE 626
L AD YS S D++ T++ +E+ + G K IG+SN ++ L+
Sbjct: 113 SLLADSDDPRAIYLVNTDGSVRYSDSLDDWITTYKQIEEEKLSGRTKSIGVSNVSEVYLK 172
Query: 627 RVLKE 641
R+L +
Sbjct: 173 RLLDQ 177
>UniRef50_P14065 Cluster: Protein GCY; n=13; Saccharomycetales|Rep:
Protein GCY - Saccharomyces cerevisiae (Baker's yeast)
Length = 312
Score = 125 bits (301), Expect = 1e-27
Identities = 71/184 (38%), Positives = 106/184 (57%), Gaps = 19/184 (10%)
Frame = +3
Query: 141 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 320
L +N G +P IGLGT+ +SK+ V+ A+ GYRH DTA++Y E ++
Sbjct: 12 LSLNTGAQIPQIGLGTW---------QSKENDAYKAVLTALKDGYRHIDTAAIYRNEDQV 62
Query: 321 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 500
G+A+K + V RE+IF+TTKLW TQH EVA ++ SLK+LGLDY+DLYLMHWP
Sbjct: 63 GQAIK----DSGVPREEIFVTTKLWCTQHHEPEVA--LDQSLKRLGLDYVDLYLMHWPAR 116
Query: 501 LNADY-SHSDV------------------DFMETWRGLEDAQRMGIVKGIGLSNFNKQQL 623
L+ Y + D+ +F++TW +++ + G K +G+SNF+ L
Sbjct: 117 LDPAYIKNEDILSVPTKKDGSRAVDITNWNFIKTWELMQELPKTGKTKAVGVSNFSINNL 176
Query: 624 ERVL 635
+ +L
Sbjct: 177 KDLL 180
>UniRef50_UPI0000E4A7CE Cluster: PREDICTED: similar to LOC553452
protein; n=6; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to LOC553452 protein -
Strongylocentrotus purpuratus
Length = 321
Score = 124 bits (300), Expect = 1e-27
Identities = 64/172 (37%), Positives = 101/172 (58%), Gaps = 12/172 (6%)
Frame = +3
Query: 156 GRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVK 335
GR +P +G GT+ + K +++ V+ AID GYRH D AS+Y E+ +G+ +K
Sbjct: 13 GRKLPLLGFGTW---------QIKPEEVGRVIETAIDCGYRHIDEASLYGNEKGVGDGIK 63
Query: 336 MKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP---IGLN 506
K+++G +KRED+F+T+KLW T + V + SL LGL Y+DL+L+H P +G
Sbjct: 64 AKIDDGTIKREDLFVTSKLWVTDSHPSRVEPSCRQSLSDLGLAYLDLFLIHCPTSAVGGK 123
Query: 507 ADYSHSD---------VDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL 635
+ D +D+++TWR +E G+V+ IG+SNF Q++RVL
Sbjct: 124 GPFPMDDNGLFIGDDTIDYVDTWRIMESLVDKGLVRAIGVSNFTVAQIQRVL 175
>UniRef50_UPI000023D0F1 Cluster: hypothetical protein FG03517.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG03517.1 - Gibberella zeae PH-1
Length = 364
Score = 124 bits (299), Expect = 2e-27
Identities = 72/202 (35%), Positives = 111/202 (54%), Gaps = 3/202 (1%)
Frame = +3
Query: 66 TICSLVE*FLVENLTELASTMEVPSLKMNNG-RDMPAIGLGTYLGFDQNGVVKSKDKQLR 242
T SLV + + ++ E+P N RD+PA GLGT+L GVV
Sbjct: 27 TAVSLVT-YTILSIATSFGPAEMPEFNKNETVRDIPAFGLGTWLA--GKGVVVP------ 77
Query: 243 DVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEV 422
V A+ GYRH DTA ++ E E+G+ +K V R++I++T KLWNT HR V
Sbjct: 78 -AVEYALKGGYRHIDTALIWRNEDEVGKGIKASG----VSRDEIWVTGKLWNTDHRPELV 132
Query: 423 AQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSD--VDFMETWRGLEDAQRMGIVKGIG 596
+AI S+ LG++Y+DLYL+H+P+ + D ++TW+ +E+ R G+ + IG
Sbjct: 133 RKAIETSIANLGVEYLDLYLIHYPVAWVPETRDVDNNTSLIDTWKAMEELVRAGLTRNIG 192
Query: 597 LSNFNKQQLERVLKEGTIKPDA 662
SNF + + ++LK +I+P A
Sbjct: 193 FSNFAPKDINKILKIASIQPYA 214
>UniRef50_Q1YPE5 Cluster: Aldehyde reductase; n=7; Bacteria|Rep:
Aldehyde reductase - gamma proteobacterium HTCC2207
Length = 330
Score = 123 bits (297), Expect = 3e-27
Identities = 73/201 (36%), Positives = 106/201 (52%), Gaps = 20/201 (9%)
Frame = +3
Query: 114 LASTMEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTA 293
++ ++VP +K+++ + MPA+GLG + K V AI VGYRH D+A
Sbjct: 1 MSDAIQVPGVKVSS-KSMPAVGLGLW---------KITQDSAAQAVYEAIKVGYRHLDSA 50
Query: 294 SVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYID 473
+ Y EQ++GE + + EG+ RE+++ITTKLWNT HR V A S+ LGLDYID
Sbjct: 51 ADYGNEQQVGEGIARAIAEGLCSREELWITTKLWNTYHRAEHVEAACRRSMDDLGLDYID 110
Query: 474 LYLMHWPIGLN-------------ADYSHSD-------VDFMETWRGLEDAQRMGIVKGI 593
LYL+H+PI L D+S D V ETW +E G+V+ I
Sbjct: 111 LYLVHFPIALRYVDFNDRYPAEWIFDHSAEDPAMELDQVPLSETWGAMEQLVESGLVRQI 170
Query: 594 GLSNFNKQQLERVLKEGTIKP 656
G+ N++ L ++ IKP
Sbjct: 171 GVCNYSAVLLHDLMSYARIKP 191
>UniRef50_A7SIT3 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 323
Score = 123 bits (296), Expect = 4e-27
Identities = 67/182 (36%), Positives = 105/182 (57%), Gaps = 11/182 (6%)
Frame = +3
Query: 144 KMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIG 323
K+N G +PA+ LGT+ +S +++ + V AI++GYRH D A +Y E EIG
Sbjct: 9 KLNTGASIPAMALGTW---------QSSKEEVGNAVRLAIELGYRHIDCAEIYGNEGEIG 59
Query: 324 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI-- 497
EA+ + EG VKRE++F+T+KLW H +V A +LK L LDY+DLYL+H P+
Sbjct: 60 EALSEVLTEGKVKREELFVTSKLWCDSHHPDDVLPACQATLKNLQLDYLDLYLIHIPVAF 119
Query: 498 --GLNADYS-------HSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTI 650
G+ +S ++ TW+ +E G+ K IG+SNF+ ++L ++L+ +I
Sbjct: 120 KKGVRLPHSIAEGIIGYTPEGVQNTWQAMEGLVAKGLCKAIGVSNFSVKRLNKLLETASI 179
Query: 651 KP 656
P
Sbjct: 180 VP 181
>UniRef50_A2QBD7 Cluster: Catalytic activity: an alcohol + NADP(+)
<=> an aldehyde + NADPH; n=4; Trichocomaceae|Rep:
Catalytic activity: an alcohol + NADP(+) <=> an aldehyde
+ NADPH - Aspergillus niger
Length = 323
Score = 123 bits (296), Expect = 4e-27
Identities = 69/189 (36%), Positives = 111/189 (58%), Gaps = 12/189 (6%)
Frame = +3
Query: 126 MEVPS-LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVY 302
M +PS +N G +PA+G GT+ ++K ++ + V A+ GYRH D A++Y
Sbjct: 1 MSLPSHFTINTGAKIPAVGFGTW---------QAKPLEVENAVEVALREGYRHIDCAAIY 51
Query: 303 ETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYL 482
E E+G ++ + V RE+IFIT KLWNT+H +V A++ +L+ LG+ Y+DLYL
Sbjct: 52 RNETEVGNGIR----KSGVPREEIFITGKLWNTKHAPEDVEPALDKTLQDLGVAYLDLYL 107
Query: 483 MHWPIG---------LNAD--YSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLER 629
MHWP LN D + +++D++ T+R +E G V+ IG+SNFN ++LE
Sbjct: 108 MHWPCAFKGGDKWFPLNDDGVFDLANIDYITTYRAMEKLLATGKVRAIGVSNFNIRRLEE 167
Query: 630 VLKEGTIKP 656
+L + ++ P
Sbjct: 168 LLGQVSVVP 176
>UniRef50_P38115 Cluster: D-arabinose dehydrogenase [NAD(P)+] heavy
chain; n=3; Saccharomycetaceae|Rep: D-arabinose
dehydrogenase [NAD(P)+] heavy chain - Saccharomyces
cerevisiae (Baker's yeast)
Length = 344
Score = 123 bits (296), Expect = 4e-27
Identities = 83/211 (39%), Positives = 120/211 (56%), Gaps = 23/211 (10%)
Frame = +3
Query: 93 LVENLTELASTMEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVG 272
+VEN+ T E+ +NNG +PA+GLGT + K + + V AI G
Sbjct: 11 IVENMLH-PKTTEI-YFSLNNGVRIPALGLGTANPHE-------KLAETKQAVKAAIKAG 61
Query: 273 YRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKK 452
YRH DTA YETE +GEA+K +E+G +KRED+FITTK+W EV +++N+SLK
Sbjct: 62 YRHIDTAWAYETEPFVGEAIKELLEDGSIKREDLFITTKVWPVLW--DEVDRSLNESLKA 119
Query: 453 LGLDYIDLYLMHWPI---------GLN------ADYS-----HSDVDFMETWRGLEDA-- 566
LGL+Y+DL L HWP+ G++ D S +D D++ET++ LE
Sbjct: 120 LGLEYVDLLLQHWPLCFEKIKDPKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYL 179
Query: 567 -QRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
V+ IG+SNF+ + LER++KE +KP
Sbjct: 180 DPNDHRVRAIGVSNFSIEYLERLIKECRVKP 210
>UniRef50_Q1U9L6 Cluster: 2,5-didehydrogluconate reductase; n=3;
Lactobacillus|Rep: 2,5-didehydrogluconate reductase -
Lactobacillus reuteri 100-23
Length = 288
Score = 122 bits (295), Expect = 6e-27
Identities = 59/173 (34%), Positives = 94/173 (54%)
Frame = +3
Query: 138 SLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 317
+ +NNG +P +G GT+ ++ V AI+ GYRH DTA+VY E+
Sbjct: 10 TFNLNNGVKIPCVGYGTF---------RTPADVAEQAVKEAIETGYRHIDTAAVYGNEEA 60
Query: 318 IGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 497
+G+ +K + +KRED+F+T+KLWNT + +A ++L +L +DY+DLYL+HWP
Sbjct: 61 VGKGIK----DSGIKREDLFVTSKLWNTNRGYEQTKKAFQETLDRLQMDYLDLYLIHWPA 116
Query: 498 GLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
+ ETWR +ED G ++ IG+SNF + ++K + P
Sbjct: 117 NEKQFGDDAAKINAETWRAMEDLYNEGKIRAIGVSNFMPHHIAELMKTAKVAP 169
>UniRef50_Q01HB5 Cluster: OSIGBa0136O08-OSIGBa0153H12.9 protein;
n=4; Oryza sativa|Rep: OSIGBa0136O08-OSIGBa0153H12.9
protein - Oryza sativa (Rice)
Length = 337
Score = 122 bits (295), Expect = 6e-27
Identities = 71/196 (36%), Positives = 104/196 (53%), Gaps = 13/196 (6%)
Frame = +3
Query: 108 TELASTMEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFD 287
T A+ VP + +N+G MP +G GT + L + A+ +GYRH D
Sbjct: 12 TPAAAATAVPCVTLNSGHAMPVLGFGTGSS--------TPPADLAATIAHAVRLGYRHLD 63
Query: 288 TASVYETEQEIGEAVKMKVEEGVV-KREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLD 464
TA+VY TE +G AV V G V R ++F+TTKL V A+ +SL +LGLD
Sbjct: 64 TAAVYGTEGAVGAAVAEAVRCGAVASRGELFVTTKLSMADAHPPRVVAALRESLSRLGLD 123
Query: 465 YIDLYLMHWPIGLNA----------DYSHSDVDF-ME-TWRGLEDAQRMGIVKGIGLSNF 608
Y+DL+L+HWP+ + D S V F ME WRG+E+ R+G+ + IG+SNF
Sbjct: 124 YVDLFLIHWPVAIGKKDAAGELTWDDLSRGLVPFDMEGVWRGMEECHRLGLARSIGVSNF 183
Query: 609 NKQQLERVLKEGTIKP 656
+ ++ R+L + P
Sbjct: 184 SAAKMSRLLALAAVPP 199
>UniRef50_Q2UGR1 Cluster: Aldo/keto reductase family proteins; n=2;
Ascomycota|Rep: Aldo/keto reductase family proteins -
Aspergillus oryzae
Length = 323
Score = 122 bits (295), Expect = 6e-27
Identities = 67/186 (36%), Positives = 102/186 (54%), Gaps = 13/186 (6%)
Frame = +3
Query: 138 SLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 317
+ K+N+G ++PAIGLGT+L SK ++ + V A+ GYRH D A+ Y+ E E
Sbjct: 6 TFKLNSGYNIPAIGLGTWL---------SKPHEVENAVEAALRAGYRHIDAAACYQNENE 56
Query: 318 IGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 497
+G K + V R+ IFIT+KLWNT H V +A+N +LK L DY+DLYL+HWP+
Sbjct: 57 VGNGWK----KSGVPRDQIFITSKLWNTHHHPEHVEEAVNKTLKDLQTDYLDLYLIHWPV 112
Query: 498 G-------------LNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLK 638
+ + ++V +TW LE ++ IG+SNF + +++ +LK
Sbjct: 113 AFEHTNETLTPIDPVTKRFRLANVPIADTWAALEKLVEAKKIRSIGISNFTQDKIDDLLK 172
Query: 639 EGTIKP 656
I P
Sbjct: 173 TAKIPP 178
>UniRef50_Q1VRG6 Cluster: YvgN; n=1; Psychroflexus torquis ATCC
700755|Rep: YvgN - Psychroflexus torquis ATCC 700755
Length = 280
Score = 122 bits (294), Expect = 8e-27
Identities = 65/172 (37%), Positives = 106/172 (61%), Gaps = 2/172 (1%)
Frame = +3
Query: 147 MNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGE 326
+N+G +P +G GTY ++ G+ KS K A+ +GYR DT ++Y+ E+ +G+
Sbjct: 5 LNDGNRIPIVGFGTYKANEEEGI-KSIQKS-------ALTLGYRLIDTVAIYQNEEAVGK 56
Query: 327 AVKMKVEEGVVKREDIFITTKLW--NTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 500
A+K + GV+ RE+IF+TTKLW N +++T +A +++SL+KL L+YIDLYL+HWP
Sbjct: 57 AIKAR---GVL-REEIFVTTKLWRENLGYKQTRIA--LDESLRKLDLNYIDLYLIHWPAN 110
Query: 501 LNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
+Y +TWR +E+ Q G +K +G+SNF + LE + + + P
Sbjct: 111 A-INYKDWQKTNADTWRAMEELQAEGKIKSLGVSNFWPEHLEALFQTAKVSP 161
>UniRef50_P51857 Cluster: 3-oxo-5-beta-steroid 4-dehydrogenase (EC
1.3.1.3) (Delta(4)-3- ketosteroid 5-beta-reductase);
n=124; cellular organisms|Rep: 3-oxo-5-beta-steroid
4-dehydrogenase (EC 1.3.1.3) (Delta(4)-3- ketosteroid
5-beta-reductase) - Homo sapiens (Human)
Length = 326
Score = 122 bits (294), Expect = 8e-27
Identities = 68/183 (37%), Positives = 100/183 (54%), Gaps = 12/183 (6%)
Frame = +3
Query: 141 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDK-QLRDVVMRAIDVGYRHFDTASVYETEQE 317
+ +++G +P IGLGTY KS K V AID GYRH D A +Y+ E E
Sbjct: 10 IPLSDGNSIPIIGLGTY------SEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHE 63
Query: 318 IGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 497
+GEA++ K+ EG V+REDIF KLW T H V + +L+ L LDY+DLY++ P+
Sbjct: 64 VGEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPM 123
Query: 498 GL-----------NADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEG 644
N + + + TW +E + G+VK +G+SNFN++QLE +L +
Sbjct: 124 AFKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKP 183
Query: 645 TIK 653
+K
Sbjct: 184 GLK 186
>UniRef50_A6NPD6 Cluster: Putative uncharacterized protein; n=3;
Bacteria|Rep: Putative uncharacterized protein -
Bacteroides capillosus ATCC 29799
Length = 287
Score = 122 bits (293), Expect = 1e-26
Identities = 71/173 (41%), Positives = 97/173 (56%), Gaps = 3/173 (1%)
Frame = +3
Query: 147 MNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGE 326
++NG +PA+G GTY D + V S AI GYRHFDTAS Y TE +G+
Sbjct: 10 LSNGLSIPAVGFGTYKTGDGDSAVLSN----------AIAQGYRHFDTASFYGTETALGQ 59
Query: 327 AVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP---I 497
AV E + RED F+T+KLW T+ +A + +L++LG DY+DLYL+HWP +
Sbjct: 60 AVA----ESDIPREDFFLTSKLWKTEMGYDAALRAFDATLERLGTDYLDLYLIHWPRPDL 115
Query: 498 GLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
L D++ D ETWR LE G+V+ IG+SNF LE +L + P
Sbjct: 116 ELE-DWAKLD---RETWRALERLYESGLVRAIGVSNFLPHHLEPILASANVAP 164
>UniRef50_Q9VHX4 Cluster: CG2767-PA; n=4; Endopterygota|Rep:
CG2767-PA - Drosophila melanogaster (Fruit fly)
Length = 329
Score = 122 bits (293), Expect = 1e-26
Identities = 72/185 (38%), Positives = 102/185 (55%), Gaps = 13/185 (7%)
Frame = +3
Query: 141 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 320
L NNG MP IG+GT+ ++ D+++ + A++ GYRH DTA VY E+ I
Sbjct: 7 LTFNNGEKMPVIGIGTW---------QASDEEIETAIDAALEAGYRHIDTAPVYGNEKAI 57
Query: 321 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP-- 494
G +K ++ G VKRE++FI TK+ +R EV I SL+ L LDY+DLYL+H P
Sbjct: 58 GRVLKRWLDAGKVKREELFIVTKVPPVSNRPHEVEPTIKKSLEDLQLDYVDLYLVHTPFT 117
Query: 495 IGLNADYSHS-------DVDFMET----WRGLEDAQRMGIVKGIGLSNFNKQQLERVLKE 641
I +N D S +VD W +E G+ K IG+SNF+K Q+ R+LK
Sbjct: 118 ININEDGSFKLDKEGLMEVDVTTNHAAIWVAMEALVEKGLTKSIGVSNFSKDQVARLLKN 177
Query: 642 GTIKP 656
I+P
Sbjct: 178 CKIRP 182
>UniRef50_Q4PDR0 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 339
Score = 122 bits (293), Expect = 1e-26
Identities = 75/192 (39%), Positives = 106/192 (55%), Gaps = 17/192 (8%)
Frame = +3
Query: 132 VPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETE 311
+PS +N G +P++G+G + G Q G +D +L D ++RAI VGYRH DTA+ Y E
Sbjct: 5 IPSFTLNTGAKLPSVGMGCWQG--QPG--PGRDNELVDALVRAIKVGYRHLDTATGYRNE 60
Query: 312 QEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHW 491
E+G+AV+ + GV R +IF+TTKL +V Q + +SL +LG+DYIDL+L+HW
Sbjct: 61 AEVGQAVR---QSGVA-RSEIFVTTKL--RPGGVHDVVQELENSLNELGIDYIDLWLLHW 114
Query: 492 PIGLNAD--------------YSHSDVDFMETWRGLEDA---QRMGIVKGIGLSNFNKQQ 620
P G D H F ETW +ED G VK IG+SNF+ +
Sbjct: 115 PQGFTKDDGGFGTGESFGLEHQKHLGPTFNETWAKMEDVFLNSHKGKVKAIGVSNFSIKN 174
Query: 621 LERVLKEGTIKP 656
LE + K + P
Sbjct: 175 LEILAKTSKVTP 186
>UniRef50_Q10494 Cluster: Probable oxidoreductase C26F1.07; n=2;
Schizosaccharomyces pombe|Rep: Probable oxidoreductase
C26F1.07 - Schizosaccharomyces pombe (Fission yeast)
Length = 321
Score = 122 bits (293), Expect = 1e-26
Identities = 68/179 (37%), Positives = 97/179 (54%), Gaps = 11/179 (6%)
Frame = +3
Query: 153 NGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAV 332
+G +P +GLGT+ +S+ Q ++ V A+ GYRH D A++Y E E+G+ +
Sbjct: 20 DGSKIPGLGLGTW---------RSEPNQTKNAVKTALQYGYRHIDAAAIYGNEDEVGDGI 70
Query: 333 KMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNA- 509
K E V R+DI++T+KLW H V +A+ +LK L LDY+D YL+HWP+
Sbjct: 71 K----ESGVPRKDIWVTSKLWCNAHAPEAVPKALEKTLKDLKLDYLDEYLIHWPVSFKTG 126
Query: 510 -DYSHSDVD---------FMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
D D D ETW+ +E G V+ IGLSNFN LER+LK +KP
Sbjct: 127 EDKFPKDKDGNLIYEKNPIEETWKAMEKLLETGKVRHIGLSNFNDTNLERILKVAKVKP 185
>UniRef50_Q9X0A2 Cluster: Oxidoreductase, aldo/keto reductase
family; n=21; Bacteria|Rep: Oxidoreductase, aldo/keto
reductase family - Thermotoga maritima
Length = 286
Score = 121 bits (292), Expect = 1e-26
Identities = 65/177 (36%), Positives = 100/177 (56%)
Frame = +3
Query: 126 MEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYE 305
M+VP + +NNG +MP +G G + + ++ + V AI VGYR DTA+ Y
Sbjct: 1 MQVPKVTLNNGVEMPILGYGVF---------QIPPEKTEECVYEAIKVGYRLIDTAASYM 51
Query: 306 TEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLM 485
E+ +G A+K ++EG+V+RE++F+TTKLW + +A SLKKL L+YIDLYL+
Sbjct: 52 NEEGVGRAIKRAIDEGIVRREELFVTTKLWVSDVGYESTKKAFEKSLKKLQLEYIDLYLI 111
Query: 486 HWPIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
H P G D W+ +E+ + G+V+ IG+SNF +L ++ I P
Sbjct: 112 HQPFG----------DVHCAWKAMEEMYKDGLVRAIGVSNFYPDRLMDLMVHHEIVP 158
>UniRef50_P70883 Cluster: AkrI; n=1; Butyrivibrio fibrisolvens|Rep:
AkrI - Butyrivibrio fibrisolvens
Length = 172
Score = 121 bits (292), Expect = 1e-26
Identities = 61/165 (36%), Positives = 92/165 (55%)
Frame = +3
Query: 141 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 320
+K+NNG +P G GTY DQN S V A+ GYRH DTA+ YE E+ +
Sbjct: 8 IKLNNGTAIPMFGYGTYKIKDQNEAYNS--------VRLALKNGYRHIDTAAFYENEKFV 59
Query: 321 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 500
A+K +EE KREDIF+T+K W T+ + A ++ ++ +DY+DLYL+HWP
Sbjct: 60 ANAIKDFMEESQTKREDIFVTSKAWKTELGYDKTLAAFEKTMNEMQMDYLDLYLVHWPAS 119
Query: 501 LNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL 635
D + + +TW+ + + + G VK IG+SNF L+ ++
Sbjct: 120 YAFDDDWENTN-RQTWKAMTEIYKSGRVKAIGVSNFLTHHLDTII 163
>UniRef50_Q7G765 Cluster: Probable NAD(P)H-dependent oxidoreductase
2; n=6; Magnoliophyta|Rep: Probable NAD(P)H-dependent
oxidoreductase 2 - Oryza sativa subsp. japonica (Rice)
Length = 322
Score = 121 bits (291), Expect = 2e-26
Identities = 68/193 (35%), Positives = 109/193 (56%), Gaps = 10/193 (5%)
Frame = +3
Query: 114 LASTMEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTA 293
+A+ EVP+ + MP IG+GT + ++ ++RAI++GYRHFDTA
Sbjct: 3 MATIPEVPASALLP--TMPRIGMGTA------AFPFTSSEETTAALLRAIELGYRHFDTA 54
Query: 294 SVYETEQEIGEAVKMKVEEGVV-KREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYI 470
+Y TE + EAV V G+V R D+F+T+KLW + V A ++L+ LG+DY+
Sbjct: 55 RLYATEGCVSEAVAEAVRRGLVASRADVFVTSKLWCSDLHAGRVVPAARETLRNLGMDYV 114
Query: 471 DLYLMHWPIGL---NADYSHSD------VDFMETWRGLEDAQRMGIVKGIGLSNFNKQQL 623
DL L+HWP + + D+ D WRG+E+ R+G+ + IG+SNF+ ++L
Sbjct: 115 DLLLVHWPATVAPGSYDFPFPKEEMAPAFDMEGVWRGMEECHRLGLARAIGVSNFSAKKL 174
Query: 624 ERVLKEGTIKPDA 662
E++L ++P A
Sbjct: 175 EQLLSFAVVRPAA 187
>UniRef50_Q927E1 Cluster: Lin2848 protein; n=13; Listeria|Rep:
Lin2848 protein - Listeria innocua
Length = 280
Score = 120 bits (289), Expect = 3e-26
Identities = 66/171 (38%), Positives = 94/171 (54%)
Frame = +3
Query: 144 KMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIG 323
++NNG +MP G G Y D+ +++R + A+DVGYR FDTAS Y E+E+G
Sbjct: 10 RLNNGIEMPRHGFGVYKLTDE--------QRMRTALETAVDVGYRLFDTASFYHNEKELG 61
Query: 324 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 503
+ G+ KR++ F+TTK+WNT+ E +A S KKL LD +DLYL+HWP
Sbjct: 62 DFF---ASSGL-KRDEFFVTTKMWNTEQGYDETLRAFEKSQKKLQLDQVDLYLVHWP--- 114
Query: 504 NADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
F ETWR +E G+V+ IG+SNF L+R+ + P
Sbjct: 115 ------KQDTFFETWRAVEKLYDEGLVRAIGVSNFEAHHLDRLRTSANVLP 159
>UniRef50_UPI00006CCCD7 Cluster: oxidoreductase, aldo/keto reductase
family protein; n=1; Tetrahymena thermophila SB210|Rep:
oxidoreductase, aldo/keto reductase family protein -
Tetrahymena thermophila SB210
Length = 323
Score = 119 bits (287), Expect = 5e-26
Identities = 66/181 (36%), Positives = 107/181 (59%), Gaps = 5/181 (2%)
Frame = +3
Query: 129 EVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYET 308
++ +++NNG MP +GLGT + V + +++ ++ A+D GYR+FDTA Y
Sbjct: 11 DIKYVQLNNGYKMPLLGLGTQ---PYDIVTRVTVEEMTTLLSNALDFGYRNFDTAKQYRN 67
Query: 309 EQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMH 488
E EIG+A + ++G KRED+FITTKL+ + + ++ + + +SL +L YIDLYL+
Sbjct: 68 EVEIGQAFQNIFQQGKYKREDVFITTKLFPFKIEK-KIKEVVQNSLDQLQTSYIDLYLIQ 126
Query: 489 W---PIGLNADYS--HSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIK 653
W P+ N D S + E WR LE+ +G+++ IG++NFN Q + +L IK
Sbjct: 127 WSFTPVLTNFDGSVAVNHRPIHEVWRELEECVELGMIRSIGVANFNCQMVLDLLSYAKIK 186
Query: 654 P 656
P
Sbjct: 187 P 187
>UniRef50_A3LTU8 Cluster: D-arabinose dehydrogenase; n=5;
Saccharomycetales|Rep: D-arabinose dehydrogenase -
Pichia stipitis (Yeast)
Length = 326
Score = 119 bits (287), Expect = 5e-26
Identities = 72/197 (36%), Positives = 114/197 (57%), Gaps = 20/197 (10%)
Frame = +3
Query: 105 LTELASTMEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHF 284
+T+LA+ ++ ++NG+ +PA+GLGT V +L++ V+ A+ GYRH
Sbjct: 1 MTQLATDVD---FVLSNGKTIPALGLGT--------VPPEDPHELKEQVITAVKAGYRHI 49
Query: 285 DTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLD 464
DTA Y TE+ IG+A+K EEG+VKRED+FITTK+W + R E ++++ SL LGLD
Sbjct: 50 DTAWYYGTEEYIGQALKQLFEEGIVKREDLFITTKVWPSFWRNPE--KSLDKSLADLGLD 107
Query: 465 YIDLYLMHWPIGLNADYSH-------------------SDVDFMETWRGLED-AQRMGIV 584
Y+DL+L HWP+ L+ D + S + +++ + LED V
Sbjct: 108 YVDLFLQHWPVVLHGDENGLPPQPRDKDGKLIYDDDPVSGIKYIDAYHSLEDIMDNTSKV 167
Query: 585 KGIGLSNFNKQQLERVL 635
K IG+SN++ +L ++L
Sbjct: 168 KSIGVSNYSIPKLRKLL 184
>UniRef50_Q838E0 Cluster: Oxidoreductase, aldo/keto reductase
family; n=24; Bacilli|Rep: Oxidoreductase, aldo/keto
reductase family - Enterococcus faecalis (Streptococcus
faecalis)
Length = 279
Score = 119 bits (286), Expect = 7e-26
Identities = 66/173 (38%), Positives = 94/173 (54%)
Frame = +3
Query: 138 SLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 317
++ +NNG +P +GLG + + D++ VV I GYR DTA +Y E
Sbjct: 8 TVTLNNGTKIPGMGLGVF---------QIPDEETAKVVEEGIINGYRLIDTAQIYGNESG 58
Query: 318 IGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 497
G +K + + RED+F+T+K+WN E QA NDSL++LGLDY+DLYL+HWP
Sbjct: 59 TGAGIKAGLAATGLNREDLFVTSKVWNAHISYDETIQAFNDSLERLGLDYLDLYLIHWP- 117
Query: 498 GLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
G N+ + E+W+ LE G VK IG+SNF LE +L + P
Sbjct: 118 GNNS--------YKESWQALETLYAEGKVKAIGVSNFQVHHLEDLLSYAKVVP 162
>UniRef50_A2FPE2 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=3; Trichomonas vaginalis G3|Rep:
Oxidoreductase, aldo/keto reductase family protein -
Trichomonas vaginalis G3
Length = 309
Score = 119 bits (286), Expect = 7e-26
Identities = 66/177 (37%), Positives = 105/177 (59%), Gaps = 14/177 (7%)
Frame = +3
Query: 165 MPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAI-DVGYRHFDTASVYETEQEIGEAVKMK 341
+P+IGLGT+L D L+ V AI D GYRH D A+ Y+ ++ IGEA+
Sbjct: 4 IPSIGLGTFLAEDPAA--------LKAAVHSAIEDSGYRHVDCAAYYKNQEIIGEALSEI 55
Query: 342 VEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNA---- 509
+G VKRE+++IT+K+WNT+HR + + + +LK+L L+Y+DL L+HW +
Sbjct: 56 FAKGQVKREEVWITSKVWNTKHRPDLLVKDVKKTLKELKLEYLDLVLVHWACAFQSREDD 115
Query: 510 DYSHSD---------VDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIK 653
+Y D +D +ETW+ +E+ +G+ K IG+SNF+ +QLER+ + +K
Sbjct: 116 EYLPRDETGKIITENIDILETWKAMEECYNLGLAKHIGVSNFSIEQLERMRYDPGVK 172
>UniRef50_UPI0000519CC2 Cluster: PREDICTED: similar to CG2767-PA;
n=1; Apis mellifera|Rep: PREDICTED: similar to CG2767-PA
- Apis mellifera
Length = 321
Score = 118 bits (285), Expect = 1e-25
Identities = 71/189 (37%), Positives = 105/189 (55%), Gaps = 13/189 (6%)
Frame = +3
Query: 126 MEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYE 305
ME ++ + NG MP IG GT+ ++++K+L D + A++ GYRH DTA+ YE
Sbjct: 1 MEKNTILLPNGELMPIIGFGTW---------QAQEKELEDALNIALEAGYRHIDTATSYE 51
Query: 306 TEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLM 485
E+ IG+ +K + +KR DIFI TKL +R +V + I SL+ L L+Y+DLYL+
Sbjct: 52 NEKVIGDVLKNWFDSKKLKRSDIFIVTKLPAVGNRAEDVEKWIKTSLQNLRLEYLDLYLI 111
Query: 486 HWPIGLN--ADYSH-----------SDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLE 626
H PIG D H + + +E W +E + G K IGLSNFN Q++
Sbjct: 112 HVPIGFEKVGDILHPFDENGHIRLDNSTNHVEIWAEMEKQVKCGRTKAIGLSNFNISQIK 171
Query: 627 RVLKEGTIK 653
R+LK +K
Sbjct: 172 RILKNTKMK 180
>UniRef50_Q4JX70 Cluster: Putative oxidoreductase; n=1;
Corynebacterium jeikeium K411|Rep: Putative
oxidoreductase - Corynebacterium jeikeium (strain K411)
Length = 285
Score = 118 bits (285), Expect = 1e-25
Identities = 65/171 (38%), Positives = 99/171 (57%)
Frame = +3
Query: 132 VPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETE 311
VP+L+MN+G+ P +GLG + + D+ V AI+ GYRH DTA++Y E
Sbjct: 8 VPTLEMNDGKTTPQLGLGVW---------QLSDEDTYTSVRAAIETGYRHIDTAAIYGNE 58
Query: 312 QEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHW 491
+ +G AV V+ G V+RE++FITTKLWN + +A +S KKLG+DY+DLYL+HW
Sbjct: 59 EAVGRAVADAVKAGDVQREELFITTKLWNADQACGK--EAFAESQKKLGMDYVDLYLLHW 116
Query: 492 PIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEG 644
P AD F++ + + + Q+ G IG+ NF + L+ + + G
Sbjct: 117 PCP-QAD------SFVQAYDSMAEIQQSGGATSIGVCNFYPEALDALKQAG 160
>UniRef50_Q03PG5 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=1; Lactobacillus brevis ATCC
367|Rep: Aldo/keto reductase of diketogulonate reductase
family - Lactobacillus brevis (strain ATCC 367 / JCM
1170)
Length = 268
Score = 118 bits (285), Expect = 1e-25
Identities = 66/171 (38%), Positives = 97/171 (56%)
Frame = +3
Query: 144 KMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIG 323
+++NG +P +G GTYL + SKD + + A+D GYRH D A +Y E +G
Sbjct: 5 QLSNGVTIPMLGFGTYL-------IDSKD--VPAAIKTALDAGYRHLDCAHIYGNEPAVG 55
Query: 324 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 503
EA+K + R D+FIT+K+WN + A + +L L LDY+DLYL+HWP
Sbjct: 56 EAIKASG----IDRSDLFITSKVWNADQGYDKTLAAFDQTLSDLQLDYLDLYLIHWP--- 108
Query: 504 NADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
N D +D TWR LE + V+ IG+SNF++ QL++V + T+KP
Sbjct: 109 NEDDFELTLD---TWRVLETLYQQKKVRAIGVSNFSEDQLKQVFEMATVKP 156
>UniRef50_Q2U219 Cluster: Aldo/keto reductase family proteins; n=6;
Pezizomycotina|Rep: Aldo/keto reductase family proteins
- Aspergillus oryzae
Length = 294
Score = 118 bits (285), Expect = 1e-25
Identities = 64/179 (35%), Positives = 101/179 (56%)
Frame = +3
Query: 120 STMEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASV 299
S P +K+N+ +P +G GT + + S +++L + + AI +GYRH D A V
Sbjct: 5 SIPNTPRVKLNDNVSIPILGYGTGTAWYKQAGDDSVNRELVEAIKTAIRLGYRHLDGAEV 64
Query: 300 YETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLY 479
Y TE E+G A+K E + RE++F+TTK+ ++ AI+ SL+KL L+Y+DLY
Sbjct: 65 YGTEAELGVAIK----ESGIPREELFVTTKVIT---NIADIPSAIDQSLRKLQLNYVDLY 117
Query: 480 LMHWPIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
L+H P ++ SD + + W +E Q+ G K IG+SN+++ LE LK I P
Sbjct: 118 LIHSPF-----FAKSDGELQQAWAAMEKVQQAGKAKAIGVSNYHQSHLEATLKTAVIAP 171
>UniRef50_P06632 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=8; Actinomycetales|Rep: 2,5-diketo-D-gluconic acid
reductase A - Corynebacterium sp. (strain ATCC 31090)
Length = 278
Score = 118 bits (284), Expect = 1e-25
Identities = 67/177 (37%), Positives = 98/177 (55%)
Frame = +3
Query: 126 MEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYE 305
M VPS+ +N+G +P +G G + V D Q V A++VGYRH DTA++Y
Sbjct: 1 MTVPSIVLNDGNSIPQLGYGVFK-------VPPADTQR--AVEEALEVGYRHIDTAAIYG 51
Query: 306 TEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLM 485
E+ +G A+ G+ R+D+FITTKLWN +H E A AI +SL KL LD +DLYL+
Sbjct: 52 NEEGVGAAI---AASGIA-RDDLFITTKLWNDRHDGDEPAAAIAESLAKLALDQVDLYLV 107
Query: 486 HWPIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
HWP +Y H+ W + + + G+ + IG+SN LER++ + P
Sbjct: 108 HWPTPAADNYVHA-------WEKMIELRAAGLTRSIGVSNHLVPHLERIVAATGVVP 157
>UniRef50_P22045 Cluster: Probable reductase; n=101; cellular
organisms|Rep: Probable reductase - Leishmania major
Length = 284
Score = 118 bits (283), Expect = 2e-25
Identities = 64/170 (37%), Positives = 93/170 (54%)
Frame = +3
Query: 147 MNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGE 326
++NG MP GLG + + + V A+ GYRH DTA++Y+ E+ +G
Sbjct: 11 LSNGVKMPQFGLGVWQS--------PAGEVTENAVNWALCAGYRHIDTAAIYKNEESVGA 62
Query: 327 AVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLN 506
++ V RED+FITTKLWNT+ A +S +KLG+DYIDLYL+HWP G +
Sbjct: 63 GLRASG----VPREDVFITTKLWNTEQGYESTLAAFEESRQKLGVDYIDLYLIHWPRGKD 118
Query: 507 ADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
S ++++WR E + V+ IG+SNF+ LE VL T+ P
Sbjct: 119 I-LSKEGKKYLDSWRAFEQLYKEKKVRAIGVSNFHIHHLEDVLAMCTVTP 167
>UniRef50_P27800 Cluster: Aldehyde reductase 1; n=18; root|Rep:
Aldehyde reductase 1 - Sporobolomyces salmonicolor
Length = 323
Score = 118 bits (283), Expect = 2e-25
Identities = 65/191 (34%), Positives = 105/191 (54%), Gaps = 16/191 (8%)
Frame = +3
Query: 132 VPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETE 311
V + +N G + +G GT+ ++ ++ V AI+ GYRH D A VY +
Sbjct: 2 VGTTTLNTGASLELVGYGTW---------QAAPGEVGQGVKVAIETGYRHLDLAKVYSNQ 52
Query: 312 QEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHW 491
E+G A+K E VKRED+FIT+KLWN HR +V A++D+LK+LGL+Y+DLYL+HW
Sbjct: 53 PEVGAAIK----EAGVKREDLFITSKLWNNSHRPEQVEPALDDTLKELGLEYLDLYLIHW 108
Query: 492 PIGL--NADYSHS--------------DVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQL 623
P+ D + + +V ++TW+ + G VK IG+SNF+ + +
Sbjct: 109 PVAFPPEGDITQNLFPKANDKEVKLDLEVSLVDTWKAMVKLLDTGKVKAIGVSNFDAKMV 168
Query: 624 ERVLKEGTIKP 656
+ +++ + P
Sbjct: 169 DAIIEATGVTP 179
>UniRef50_A6ESC0 Cluster: ARA1; n=1; unidentified eubacterium
SCB49|Rep: ARA1 - unidentified eubacterium SCB49
Length = 280
Score = 117 bits (282), Expect = 2e-25
Identities = 58/171 (33%), Positives = 98/171 (57%)
Frame = +3
Query: 144 KMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIG 323
K+NN ++PAIG GT+ D + + + AID GY+H D A++Y+ E+ +G
Sbjct: 6 KLNNNINIPAIGFGTWQTPDGQTAINA--------IKTAIDAGYKHIDAAAIYKNEKGVG 57
Query: 324 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 503
+K E + R+D+F+T+K+WN Q +A ++++ L LDY+DLYL+HWP
Sbjct: 58 LGIK----EANIDRKDLFVTSKVWNEQRGYENTLKAFDNTINDLQLDYLDLYLIHWPAAA 113
Query: 504 NADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
+ + ++ +TW +E + G +K +G+SNF + L +L+ TIKP
Sbjct: 114 HQFENWKQLN-NDTWSAMEKLYKDGKIKALGVSNFMEHHLTPLLQHATIKP 163
>UniRef50_Q5KI95 Cluster: Aldo-keto reductase, putative; n=14;
Dikarya|Rep: Aldo-keto reductase, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 353
Score = 117 bits (282), Expect = 2e-25
Identities = 69/192 (35%), Positives = 103/192 (53%), Gaps = 15/192 (7%)
Frame = +3
Query: 126 MEVP-SLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVY 302
M P S K+N G +PAIGLGT+ ++K ++R V A+ GYRH D A Y
Sbjct: 33 MSAPTSFKLNTGASIPAIGLGTW---------QAKAGEVRQAVAHALKAGYRHIDGALCY 83
Query: 303 ETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYL 482
+ E E+G +K + V R +IF+T+K+W++ H R E + ++ +LK L DY+DLYL
Sbjct: 84 QNEDEVGLGIK----DSGVPRSEIFLTSKVWSSYHDRVE--ECLDTTLKSLQTDYLDLYL 137
Query: 483 MHWPIGLNADYSHS--------------DVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQ 620
+HWP+ L + +H D D +TW +ED + G K IGLSN
Sbjct: 138 IHWPVRLAPNGTHPLFPVKPDGSRNLDWDWDQAKTWAQMEDVLKKGKAKAIGLSNAGIPI 197
Query: 621 LERVLKEGTIKP 656
+E ++K G + P
Sbjct: 198 IEHIIKTGKVTP 209
>UniRef50_UPI00015B5BD7 Cluster: PREDICTED: similar to aldo-keto
reductase; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to aldo-keto reductase - Nasonia vitripennis
Length = 310
Score = 117 bits (281), Expect = 3e-25
Identities = 69/188 (36%), Positives = 112/188 (59%), Gaps = 5/188 (2%)
Frame = +3
Query: 111 ELASTMEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDT 290
E A T + L++NNG DMP +G+GTY V+ ++ ++ V+ + VG+R DT
Sbjct: 16 EAALTPTIRDLRLNNGYDMPLVGIGTYK-------VRGREV-IKRVIDESFAVGFRSIDT 67
Query: 291 ASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTE-VAQAINDSLKKLGLDY 467
A VY E++IG A+K + + +KREDIFIT+KL + + + + +++ DSLK L Y
Sbjct: 68 AVVYRNEEDIGLALKELLPKYNLKREDIFITSKLSPSDNGDPDKIRKSVEDSLKALDTSY 127
Query: 468 IDLYLMHWPIGLNADYSHSDVD---FMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLK 638
+DLYL+HWP G + +S + + TW L + Q+ G+++ IG+SN+ LE +L+
Sbjct: 128 LDLYLIHWP-GASRILENSPDNPKLRVTTWATLVELQQKGLLRSIGVSNYTVGHLEHLLE 186
Query: 639 E-GTIKPD 659
+KPD
Sbjct: 187 HCSGVKPD 194
>UniRef50_Q8F1G4 Cluster: Aldehyde reductase; n=8; Bacteria|Rep:
Aldehyde reductase - Leptospira interrogans
Length = 278
Score = 117 bits (281), Expect = 3e-25
Identities = 61/174 (35%), Positives = 101/174 (58%), Gaps = 1/174 (0%)
Frame = +3
Query: 138 SLKMNNGRDMPAIGLGTYLGFDQNGVVKSKD-KQLRDVVMRAIDVGYRHFDTASVYETEQ 314
++ +NNG MP +GLG + K+K K+ ++ V+ A++ GYRH DTA +Y+ E
Sbjct: 11 TIMLNNGISMPILGLGVW---------KTKSGKECKEAVLNALEAGYRHIDTARIYDNEV 61
Query: 315 EIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 494
++G+A++ E + R++IFITTKLWN + +A+ +SL +LG+D++DLYL+H+P
Sbjct: 62 DVGQAIR----ESGIPRKEIFITTKLWNADQGSDKTRKALENSLDRLGIDFVDLYLIHFP 117
Query: 495 IGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
+ M++W+ LE + K IG+SN+ L +LK I P
Sbjct: 118 VTSKR---------MDSWKELEKLYHDKLCKAIGVSNYTIIHLTELLKNSQITP 162
>UniRef50_Q9ZUJ6 Cluster: T2K10.1 protein; n=16; core
eudicotyledons|Rep: T2K10.1 protein - Arabidopsis
thaliana (Mouse-ear cress)
Length = 176
Score = 117 bits (281), Expect = 3e-25
Identities = 68/181 (37%), Positives = 99/181 (54%), Gaps = 13/181 (7%)
Frame = +3
Query: 120 STMEVPSLKMNNG----RDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFD 287
S VP+L + +G MP +G GT + L++ V+ AI +GYRHFD
Sbjct: 2 SLTTVPTLAIRSGPSGHHSMPVLGFGTAAS------PLPEPTMLKETVIEAIKLGYRHFD 55
Query: 288 TASVYETEQEIGEAVKMKVEEGVVK-REDIFITTKLWNTQHRRTEVAQAINDSLKKLGLD 464
T+ Y+TE+ IGEA+ V G+V+ R + F+TTKLW V AI SLK L LD
Sbjct: 56 TSPRYQTEEPIGEALAEAVSLGLVRSRSEFFVTTKLWCADAHGGLVVPAIKRSLKNLKLD 115
Query: 465 YIDLYLMHWPIGLNA--------DYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQ 620
Y+DLY++HWP+ + +DF W +E+ QR+G+ K IG+SNF+ ++
Sbjct: 116 YLDLYIIHWPVSSKPGKYKFPIDEDDFMPMDFEVVWSEMEECQRLGLAKCIGVSNFSCKK 175
Query: 621 L 623
L
Sbjct: 176 L 176
>UniRef50_A6RKL9 Cluster: Putative uncharacterized protein; n=3;
Sclerotiniaceae|Rep: Putative uncharacterized protein -
Botryotinia fuckeliana B05.10
Length = 360
Score = 117 bits (281), Expect = 3e-25
Identities = 64/191 (33%), Positives = 108/191 (56%), Gaps = 4/191 (2%)
Frame = +3
Query: 90 FLVENLTELASTME---VPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRA 260
FL+ N+ L + E + P IG GT+ +K + + V A
Sbjct: 11 FLLSNINALYLSAEQHPIAPPSQKQSISQPLIGFGTWN-------LKVSPENTTEAVAYA 63
Query: 261 IDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTE-VAQAIN 437
I++GYR D A+VY E +G ++ ++ +KREDI++T+KLWN H E V + +N
Sbjct: 64 IEIGYRQIDCAAVYGNEVAVGRGIEEGLKRAGLKREDIWVTSKLWNDHHGSYENVEKGLN 123
Query: 438 DSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQ 617
+L+ LGL+Y+DLYL+HWPIG +++ ++D ++T++ + + ++ IG+SNF+
Sbjct: 124 QTLQDLGLEYLDLYLIHWPIGFSSN-GAKNLDHVQTYKSMISLPKSRVL-NIGVSNFSPL 181
Query: 618 QLERVLKEGTI 650
QL+ V+ GTI
Sbjct: 182 QLKNVVSTGTI 192
>UniRef50_UPI00015B40FA Cluster: PREDICTED: similar to CG2767-PA;
n=2; Nasonia vitripennis|Rep: PREDICTED: similar to
CG2767-PA - Nasonia vitripennis
Length = 356
Score = 116 bits (280), Expect = 4e-25
Identities = 73/187 (39%), Positives = 103/187 (55%), Gaps = 14/187 (7%)
Frame = +3
Query: 138 SLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 317
++K+++G DMP IGLGT+ + + + V A++ GYRH DTA Y E+
Sbjct: 27 TIKLSSGHDMPMIGLGTW---------QMPPEAIEVAVTAALESGYRHIDTAFTYGNEEA 77
Query: 318 IGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 497
IG+ +K ++G KRED+FITTKL R V + SL+KLGL+Y+++YL+H P
Sbjct: 78 IGKTLKKWFDKGG-KREDLFITTKLPPIGMRAEYVESYLKLSLEKLGLEYVNMYLIHKPF 136
Query: 498 -----------GLNADYS---HSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL 635
LN D S +D D + WR +E + G V+ IGLSNFNK QL V
Sbjct: 137 AFVKDKYKYEPALNPDGSVVLDTDTDHVAIWRAMEKQVKAGRVRSIGLSNFNKSQLLNVY 196
Query: 636 KEGTIKP 656
+ IKP
Sbjct: 197 EHAEIKP 203
>UniRef50_Q8ZI40 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=74; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase
A - Yersinia pestis
Length = 277
Score = 116 bits (280), Expect = 4e-25
Identities = 65/178 (36%), Positives = 105/178 (58%)
Frame = +3
Query: 123 TMEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVY 302
TM+ P +K+ +GR MP +GLG + ++ ++ V +A++VGYR DTA++Y
Sbjct: 2 TMQ-PLIKLYDGRLMPQLGLGVW---------QASIQETELAVSKALEVGYRSIDTAAIY 51
Query: 303 ETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYL 482
+ E+ +G+A+K V R+++FITTKLWN + QA+ SL+KL LDY+DLYL
Sbjct: 52 KNEEGVGKALKA----AAVARDELFITTKLWNDDQHNPQ--QALETSLQKLQLDYVDLYL 105
Query: 483 MHWPIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
+HWP + H ++ WR L + G+++ IG+ NF+ L+R++ E I P
Sbjct: 106 IHWP---DPKQDH----YVSAWRELVTLKEQGLIRSIGVCNFHIPHLQRLIDETGIAP 156
>UniRef50_UPI00006CA3CB Cluster: oxidoreductase, aldo/keto reductase
family protein; n=3; Tetrahymena thermophila SB210|Rep:
oxidoreductase, aldo/keto reductase family protein -
Tetrahymena thermophila SB210
Length = 299
Score = 116 bits (279), Expect = 5e-25
Identities = 68/184 (36%), Positives = 107/184 (58%), Gaps = 5/184 (2%)
Frame = +3
Query: 120 STMEVPS-LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTAS 296
S+ E+ + ++NG+ MPA GLG+ V+S + ++ +++ +A+DVGYRH DTA
Sbjct: 2 SSQEIQKVITLSNGQKMPAFGLGS-------SRVQSVE-EVTNLIRKALDVGYRHIDTAQ 53
Query: 297 VYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDL 476
+YE EQ IG A+K EG KREDIF+ TK + + + + L+KL +DY+DL
Sbjct: 54 MYENEQFIGAALKTIFGEGKYKREDIFLVTK--QASIKGVSCLEIMKEQLQKLQVDYVDL 111
Query: 477 YLMHWPIGLNAD----YSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEG 644
L+H P+ +D ++H V + W E+ +G+ KG+G+SNFN Q + +L
Sbjct: 112 LLIHVPLAAPSDDYQQWNHKPVH--QIWAEFEEIHSLGLAKGLGVSNFNCQMIIDLLAYC 169
Query: 645 TIKP 656
IKP
Sbjct: 170 KIKP 173
>UniRef50_A7BA05 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 292
Score = 116 bits (279), Expect = 5e-25
Identities = 67/178 (37%), Positives = 94/178 (52%)
Frame = +3
Query: 132 VPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETE 311
+P+ + G +P +G GTY K + D V RA++VGYRH DTA +Y E
Sbjct: 16 IPTFMLPTGSPIPVLGFGTY---------KVAPEDTYDAVSRALEVGYRHIDTAQMYGNE 66
Query: 312 QEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHW 491
E+G A+ E + RED+FITTK+ N+ H A +I SL+ L DY+DL L+HW
Sbjct: 67 AEVGAAL----EASGIAREDLFITTKVDNSNHEPDRAAASIRRSLEDLRTDYVDLLLVHW 122
Query: 492 PIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAI 665
P L Y D W LEDA G + IGLSN+ ++ +E V + T+ P +
Sbjct: 123 P--LPTLYGG---DVALPWPALEDAFNAGGARAIGLSNYEREHVEAVREVATVAPHVL 175
>UniRef50_Q4Q5N9 Cluster: Prostaglandin f synthase, putative; n=7;
cellular organisms|Rep: Prostaglandin f synthase,
putative - Leishmania major
Length = 279
Score = 116 bits (279), Expect = 5e-25
Identities = 66/170 (38%), Positives = 91/170 (53%)
Frame = +3
Query: 147 MNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGE 326
++NG +P +G+GT+ D N VV K A++ GYRH DTA Y+ E+ +G+
Sbjct: 10 LSNGVQVPQLGIGTWEAKDGNEVVNIK---------WAVNAGYRHVDTAHYYKNEKGVGQ 60
Query: 327 AVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLN 506
+ E V R DIF+TTKLWN H A S + LG++Y+DLYL+HWP G N
Sbjct: 61 GIS----ECGVPRSDIFVTTKLWNYDHGYESALAAFEQSRQALGVEYVDLYLIHWP-GPN 115
Query: 507 ADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
Y +ETWR E M V+ IG+SNF L+ +L T+ P
Sbjct: 116 RSY-------IETWRAFEKLYEMKKVRAIGVSNFEPHHLDDLLANCTVPP 158
>UniRef50_Q22352 Cluster: Putative uncharacterized protein T08H10.1;
n=2; Caenorhabditis|Rep: Putative uncharacterized
protein T08H10.1 - Caenorhabditis elegans
Length = 333
Score = 116 bits (279), Expect = 5e-25
Identities = 67/190 (35%), Positives = 103/190 (54%), Gaps = 13/190 (6%)
Frame = +3
Query: 126 MEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRA-IDVGYRHFDTASVY 302
M V S+ +N G +P GLGT+ + KD+ V +RA +D GYR DTA +Y
Sbjct: 1 MTVDSIPLNTGAQLPLFGLGTW---------QVKDEAELTVALRAALDAGYRLIDTAHLY 51
Query: 303 ETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYL 482
+ E IG+ + + G +KREDIF+T+KL T H +V + + LK L L+YIDLYL
Sbjct: 52 QNEHIIGKVLHEYISSGKLKREDIFVTSKLPFTAHAPEDVPKCVESQLKALQLEYIDLYL 111
Query: 483 MHWPIGL------------NADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLE 626
+H P N + + +++ ++TWR LE + G +K +G+SNF+ QL+
Sbjct: 112 IHCPFPFKHQEGSFAPLMENGELAVTEIAHIDTWRALEKLYKEGKLKALGVSNFSCNQLQ 171
Query: 627 RVLKEGTIKP 656
+ +KP
Sbjct: 172 ALYDAAEVKP 181
>UniRef50_A1D4E3 Cluster: D-xylose reductase (Xyl1), putative; n=5;
Pezizomycotina|Rep: D-xylose reductase (Xyl1), putative
- Neosartorya fischeri (strain ATCC 1020 / DSM 3700 /
NRRL 181)(Aspergillus fischerianus (strain ATCC 1020 /
DSM 3700 / NRRL 181))
Length = 321
Score = 116 bits (279), Expect = 5e-25
Identities = 68/193 (35%), Positives = 95/193 (49%), Gaps = 16/193 (8%)
Frame = +3
Query: 126 MEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYE 305
M PS K+N+G DMP +G G + K ++ D + AI GYR FD A Y
Sbjct: 1 MTTPSTKLNSGYDMPLVGFGLW---------KVNNETCADQIYHAIKAGYRLFDGACDYG 51
Query: 306 TEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLM 485
E E G+ V ++EG+VKRED+FI +KLWN+ H V L GLDY DL+++
Sbjct: 52 NEVEAGKGVARAIQEGIVKREDLFIVSKLWNSFHDGDRVEPICRKQLADWGLDYFDLFIV 111
Query: 486 HWPIGL----------------NADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQ 617
H+PI L N S+ ETW +E + + IG+SNF+ Q
Sbjct: 112 HFPIALKYVDPAVRYPPGWLSENNKLEFSNASIQETWTAMESLVDKKLARSIGVSNFSAQ 171
Query: 618 QLERVLKEGTIKP 656
L +L+ I+P
Sbjct: 172 LLMDLLRYARIRP 184
>UniRef50_Q03XK0 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=3; Lactobacillales|Rep: Aldo/keto
reductase of diketogulonate reductase family -
Leuconostoc mesenteroides subsp. mesenteroides (strain
ATCC 8293 /NCDO 523)
Length = 292
Score = 115 bits (277), Expect = 9e-25
Identities = 63/168 (37%), Positives = 92/168 (54%)
Frame = +3
Query: 153 NGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAV 332
+G +MP +G G + + G K V+ AI GYR DTA+ Y E+E+GEA+
Sbjct: 8 SGIEMPLLGFGVFQ-VQEKGAAKQ-------AVLDAIKTGYRLIDTAASYGNEREVGEAI 59
Query: 333 KMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNAD 512
+ +G+VKRE++F+T+K+W + AI SL++L LDY+DLYL+H P
Sbjct: 60 LEAINQGIVKREELFVTSKMWVQDVSAQQATAAIQSSLQRLNLDYLDLYLIHQPYN---- 115
Query: 513 YSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
D WR +E A R G +K IG+SNF+ QL + + IKP
Sbjct: 116 ------DVFGAWRAMESAYRSGQLKAIGVSNFDIAQLTNLAEFSDIKP 157
>UniRef50_Q17DN1 Cluster: Aldo-keto reductase; n=1; Aedes
aegypti|Rep: Aldo-keto reductase - Aedes aegypti
(Yellowfever mosquito)
Length = 284
Score = 115 bits (277), Expect = 9e-25
Identities = 70/178 (39%), Positives = 100/178 (56%), Gaps = 2/178 (1%)
Frame = +3
Query: 129 EVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYET 308
+ P +K+NNG +MP +GLGT+L + GV + + AID GYRH DTA Y+
Sbjct: 4 KAPMVKLNNGLEMPVLGLGTWLSKEGEGV---------EAIKAAIDAGYRHIDTAYFYQN 54
Query: 309 EQEIGEAVKMKVEEGVVKREDIFITTKL--WNTQHRRTEVAQAINDSLKKLGLDYIDLYL 482
E+E+GEA++ K+EEGVV RED+F+TTK W+T++ A + L+ +DYID
Sbjct: 55 EKEVGEAIRAKIEEGVVCREDLFVTTKFIDWDTKNLMPYDA---DGKLQFSDVDYID--- 108
Query: 483 MHWPIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
TW+ +E + G VK IG+SNFN +Q+ R+L E IKP
Sbjct: 109 --------------------TWKAMEKLLKTGKVKSIGVSNFNSEQITRLLAECEIKP 146
>UniRef50_UPI00006CD296 Cluster: oxidoreductase, aldo/keto reductase
family protein; n=1; Tetrahymena thermophila SB210|Rep:
oxidoreductase, aldo/keto reductase family protein -
Tetrahymena thermophila SB210
Length = 295
Score = 115 bits (276), Expect = 1e-24
Identities = 63/169 (37%), Positives = 99/169 (58%), Gaps = 1/169 (0%)
Frame = +3
Query: 153 NGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAV 332
NG +P GLGTY V SK++ + + A+D+GYRH DTA +YE E++IG+A+
Sbjct: 12 NGSKLPVFGLGTYK-------VVSKEEMVT-FLRTALDLGYRHIDTAIMYENEKQIGDAL 63
Query: 333 KMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNAD 512
+ +EG KRED+F+ TKL++ ++ T+V + SL+ L +YIDLYL+H+ D
Sbjct: 64 QEIYKEGKYKREDLFLVTKLFS--NKNTKVEDQVRQSLQNLQTNYIDLYLLHYASSPPTD 121
Query: 513 -YSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
+ + + W E+ + G+++ IG+SNFN Q L + IKP
Sbjct: 122 QFELTHKPVFQVWAEFEELVQKGLIRNIGISNFNVQMLLDLYSYCKIKP 170
>UniRef50_UPI0000499B0E Cluster: oxidoreductase, aldo/keto reductase
family; n=1; Entamoeba histolytica HM-1:IMSS|Rep:
oxidoreductase, aldo/keto reductase family - Entamoeba
histolytica HM-1:IMSS
Length = 307
Score = 115 bits (276), Expect = 1e-24
Identities = 70/179 (39%), Positives = 103/179 (57%), Gaps = 9/179 (5%)
Frame = +3
Query: 147 MNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGE 326
+NNG+ MPAIGLGT+L + ++ V A++ GYR D A Y+ E+EIGE
Sbjct: 8 LNNGKFMPAIGLGTWL---------AAPGEVGKAVTLALENGYRLIDCARFYKNEKEIGE 58
Query: 327 AVKMKVEEGVVK--REDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 500
M +E + RE++F+T+KLW Q T + ++ +S++ L Y+DLYL+HWPI
Sbjct: 59 ---MGIEPFLKNHPREELFVTSKLWMDQV--TRIRESCLESIQDLKCKYLDLYLIHWPIA 113
Query: 501 LNADYSHS-------DVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
L D S+ D+D E W+ +E G+VK IGLSNF Q+E+++K IKP
Sbjct: 114 LKVDASNPPKPEDFLDMDITEIWQEMERLVDEGLVKSIGLSNFTIPQIEKIMKMCRIKP 172
>UniRef50_Q05KR9 Cluster: Benzil reductase; n=5; Bacillales|Rep:
Benzil reductase - Bacillus subtilis
Length = 276
Score = 115 bits (276), Expect = 1e-24
Identities = 66/173 (38%), Positives = 96/173 (55%)
Frame = +3
Query: 138 SLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 317
++K++NG +MP GLG + + N +S V AI GYR DTA++Y+ E+
Sbjct: 8 TVKLHNGVEMPWFGLGVFKVENGNEATES--------VKAAIKNGYRSIDTAAIYKNEEG 59
Query: 318 IGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 497
+G +K E GV RE++FIT+K+WN A SL++L LDY+DLYL+HWP
Sbjct: 60 VGIGIK---ESGVA-REELFITSKVWNEDQGYETTLAAFEKSLERLQLDYLDLYLIHWP- 114
Query: 498 GLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
+ +TWR LE + G ++ IG+SNF LE +LK+ IKP
Sbjct: 115 --------GKDKYKDTWRALEKLYKDGKIRAIGVSNFQVHHLEELLKDAEIKP 159
>UniRef50_UPI00015B4B22 Cluster: PREDICTED: similar to GA15457-PA;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
GA15457-PA - Nasonia vitripennis
Length = 388
Score = 114 bits (275), Expect = 2e-24
Identities = 70/193 (36%), Positives = 103/193 (53%), Gaps = 12/193 (6%)
Frame = +3
Query: 114 LASTMEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTA 293
L V LK+++G ++PA+GLGT +K + + + + A++ GYRH DTA
Sbjct: 17 LPGAQAVEKLKLSSGHEIPAVGLGT-------STIKLDE--MDNAISSALENGYRHIDTA 67
Query: 294 SVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYID 473
Y+ E IG+ +K ++G KREDIFIT+KL + +R V + SLK LGLDY+D
Sbjct: 68 FSYDNEAAIGKILKKWFDKGG-KREDIFITSKLPSQGNRPQSVETYLKRSLKDLGLDYVD 126
Query: 474 LYLMHWPIGLNADYSHS------------DVDFMETWRGLEDAQRMGIVKGIGLSNFNKQ 617
+YL+H P + + S DVD W+ +E + G K IGLSNFN+
Sbjct: 127 MYLIHTPFAVKEGENLSSKQDKDGNDLFDDVDHKALWKAMERQVKEGRAKSIGLSNFNQS 186
Query: 618 QLERVLKEGTIKP 656
Q+ + IKP
Sbjct: 187 QVLNIYNNAEIKP 199
>UniRef50_Q7NB44 Cluster: ARA1; n=3; Firmicutes|Rep: ARA1 -
Mycoplasma gallisepticum
Length = 289
Score = 114 bits (275), Expect = 2e-24
Identities = 66/183 (36%), Positives = 100/183 (54%), Gaps = 4/183 (2%)
Frame = +3
Query: 120 STMEVPSLKMN---NGRDMPAIGLGTYLGFDQNGVVKSKD-KQLRDVVMRAIDVGYRHFD 287
+T ++ +K N N MP+IG GTY K +D KQ + V A++VGYRH D
Sbjct: 4 TTKKIKVMKYNLLANNYKMPSIGFGTY---------KLEDGKQTVEAVKTALEVGYRHLD 54
Query: 288 TASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDY 467
A +YE + + + +K+ V R++IFIT+K+WN +A + LK L L+Y
Sbjct: 55 CAEIYENQLSVSQGIKLSG----VNRKEIFITSKIWNDDKGYESTKKAFHKILKDLDLEY 110
Query: 468 IDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGT 647
+DL L+HWPIG + +V+ +TW+ +E+ G +K IGLSNF +E + K
Sbjct: 111 LDLLLIHWPIGKGFKDNWQEVN-AQTWKAMEEFYLEGKIKAIGLSNFLVHHIEALKKSAK 169
Query: 648 IKP 656
I P
Sbjct: 170 ILP 172
>UniRef50_A7P424 Cluster: Chromosome chr1 scaffold_5, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr1 scaffold_5, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 247
Score = 114 bits (275), Expect = 2e-24
Identities = 62/188 (32%), Positives = 109/188 (57%), Gaps = 11/188 (5%)
Frame = +3
Query: 126 MEVPSLKMNN-GRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVY 302
+ +P + + + G+ +P +G+ T + + + + D ++ AI++GYRHFD + Y
Sbjct: 2 ISIPEMTLGSTGKAIPLVGMVTTV------YPFAPSETMIDSILTAIELGYRHFDCVAAY 55
Query: 303 ETEQEIGEAVKMKVEEGVVK-REDIFITTKLWNTQHRRTEVAQAINDSL---------KK 452
+E+ +GEA+K V+ G++K R+++FIT+KLW + V A+ ++L K
Sbjct: 56 LSEKPLGEAIKKAVKLGLIKSRDELFITSKLWCSDAHHDRVLPALQNTLKISSILSFSKN 115
Query: 453 LGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERV 632
L LDY+DLYL+HW G H +D W+ +ED Q++ + K IG+SNF+ +LE +
Sbjct: 116 LQLDYLDLYLIHWSDG------HLPIDLGSVWKAMEDFQKLSLTKAIGVSNFSCNKLEEL 169
Query: 633 LKEGTIKP 656
L+ +I P
Sbjct: 170 LQTASILP 177
>UniRef50_A2EHN6 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=10; Trichomonas vaginalis|Rep:
Oxidoreductase, aldo/keto reductase family protein -
Trichomonas vaginalis G3
Length = 312
Score = 114 bits (275), Expect = 2e-24
Identities = 66/183 (36%), Positives = 101/183 (55%), Gaps = 16/183 (8%)
Frame = +3
Query: 162 DMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAID-VGYRHFDTASVYETEQEIGEAVKM 338
++P +G GTYL D +L+ + AI+ G RH DTA Y + IGE +K
Sbjct: 2 EIPQLGFGTYLANDP--------AKLKAALHYAIEECGVRHIDTAFAYYNQNVIGETLKE 53
Query: 339 KVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNA--- 509
+G +KRED+FITTKLW T HR+ V ++++L +L L Y+DL+L+H PI +
Sbjct: 54 IFAKGKIKREDMFITTKLWCTHHRKDLVEPELHENLAQLQLSYVDLFLIHQPIAFKSLPA 113
Query: 510 ------------DYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIK 653
+ +D +ET+ +E+ Q+ G+ + IG+SNF+ +QLER+ IK
Sbjct: 114 KDGTMMPKDEKGKIQYEQIDILETYHAMEECQKKGLTRHIGVSNFSIEQLERIWFNCEIK 173
Query: 654 PDA 662
P A
Sbjct: 174 PYA 176
>UniRef50_A6W8E7 Cluster: 2,5-didehydrogluconate reductase; n=3;
Actinomycetales|Rep: 2,5-didehydrogluconate reductase -
Kineococcus radiotolerans SRS30216
Length = 289
Score = 113 bits (273), Expect = 3e-24
Identities = 65/179 (36%), Positives = 104/179 (58%)
Frame = +3
Query: 120 STMEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASV 299
S M VP++ +N+GR++P +G G + + + V A+D+GYRH DTA +
Sbjct: 8 SAMTVPTILLNDGREIPQLGFGVF---------QIEPGDTAQAVKTALDLGYRHIDTAQM 58
Query: 300 YETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLY 479
Y E E+ + + + GV R++I++T+KL N H +A++DS++KL IDLY
Sbjct: 59 YGNEAEVAQGI---ADSGV-PRDEIWVTSKLNNGFHEPDAARKAVDDSVEKLR-GPIDLY 113
Query: 480 LMHWPIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
L+HWP L Y DF+ TW+ LE+A+ G ++ IG+SNF L+R+ +E T+ P
Sbjct: 114 LIHWP--LPTLYGG---DFVSTWKVLEEARAAGKLRSIGVSNFQVNHLQRLAQEATVVP 167
>UniRef50_Q7PM68 Cluster: ENSANGP00000014386; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000014386 - Anopheles gambiae
str. PEST
Length = 310
Score = 113 bits (273), Expect = 3e-24
Identities = 64/176 (36%), Positives = 96/176 (54%), Gaps = 12/176 (6%)
Frame = +3
Query: 165 MPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKV 344
+P IGLGTY +G ++ + AIDVGYR FDTA Y E +GEA++ K+
Sbjct: 17 LPTIGLGTYSILGADG---------KEAIRTAIDVGYRMFDTAVAYGNEAIVGEAIREKI 67
Query: 345 EE-GVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYS- 518
E + R+D FI +KL + HR+ V + +L +LG+DY+DLYLMH P+ L ++
Sbjct: 68 RECNNLTRDDFFIISKLSGSYHRQDLVEKCCRMTLDRLGMDYVDLYLMHTPVALQSEKKC 127
Query: 519 ----------HSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
+ E W GLE + G+ + IG+SNFN+ Q+ +L + +I P
Sbjct: 128 ARNGTKLNAIDDSIAPTEAWIGLEQCYQEGLCRSIGVSNFNEHQINALLSDASIVP 183
>UniRef50_P15339 Cluster: 2,5-diketo-D-gluconic acid reductase B;
n=6; Actinomycetales|Rep: 2,5-diketo-D-gluconic acid
reductase B - Corynebacterium sp. (strain SHS752001)
Length = 277
Score = 113 bits (273), Expect = 3e-24
Identities = 65/175 (37%), Positives = 97/175 (55%)
Frame = +3
Query: 132 VPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETE 311
+P++ +N+GR GLGTY GV ++ AID GYR DTA YE E
Sbjct: 4 IPTISLNDGRPFAEPGLGTYNLRGDEGVA---------AMVAAIDSGYRLLDTAVNYENE 54
Query: 312 QEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHW 491
E+G AV+ V R+++ + +K+ QH R E +I SL +LGLD IDL L+HW
Sbjct: 55 SEVGRAVRASS----VDRDELIVASKIPGRQHGRAEAVDSIRGSLDRLGLDVIDLQLIHW 110
Query: 492 PIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
P + S +++TWRG+ DA+ G+V+ IG+SNF + L+ ++ E + P
Sbjct: 111 P-------NPSVGRWLDTWRGMIDAREAGLVRSIGVSNFTEPMLKTLIDETGVTP 158
>UniRef50_Q568D7 Cluster: Zgc:110366; n=7; Euteleostomi|Rep:
Zgc:110366 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 289
Score = 113 bits (272), Expect = 4e-24
Identities = 66/181 (36%), Positives = 99/181 (54%), Gaps = 2/181 (1%)
Frame = +3
Query: 120 STMEVPSLKMNNGRDMPAIGLGT--YLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTA 293
+ + P++ ++NG ++P +GLGT Y G+ V+ + + G RH DTA
Sbjct: 9 TALSCPAVPLHNGLNIPILGLGTSHYGGYSHEAVLYALQ-----------ECGIRHIDTA 57
Query: 294 SVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYID 473
Y E+ +G+AV E GV +RE++++TTKLW + QA DS +LG+DY+D
Sbjct: 58 KRYGCEEALGKAV---TESGV-QREELWVTTKLWPGDYGYQSTKQACRDSRARLGVDYLD 113
Query: 474 LYLMHWPIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIK 653
LYLMHWP + S +V +ETWR LE+ G+ + IG+SNF L + G I
Sbjct: 114 LYLMHWPDSMVPGRSSQEVR-LETWRALEELYDEGLCRAIGVSNFLIPHLNELKDSGGIV 172
Query: 654 P 656
P
Sbjct: 173 P 173
>UniRef50_Q5FK99 Cluster: Oxidoreductase aldo-keto reductase family;
n=5; Lactobacillus|Rep: Oxidoreductase aldo-keto
reductase family - Lactobacillus acidophilus
Length = 289
Score = 113 bits (272), Expect = 4e-24
Identities = 65/176 (36%), Positives = 95/176 (53%)
Frame = +3
Query: 129 EVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYET 308
++P +K+N+G ++P +G G + + + VK+ V AI GYR DTA Y
Sbjct: 3 DIPKIKLNDGNEIPQLGFGVFQISNHDEAVKA--------VESAISNGYRLIDTAEAYNN 54
Query: 309 EQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMH 488
+ +GEA+K V R+DIF+TTKLW + + ++AI++ LK+LG DYID+ L+H
Sbjct: 55 QTAVGEAIK----NSDVNRDDIFLTTKLWVSNFTYEKASKAIDEDLKELGTDYIDMMLLH 110
Query: 489 WPIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
G D WR LEDAQ+ G K IG+SNF QL + +KP
Sbjct: 111 QAYG----------DVAGAWRALEDAQKAGKTKSIGVSNFWPDQLMNLQLMSNVKP 156
>UniRef50_UPI000065D0BD Cluster: Homolog of Homo sapiens "AKR1B1
protein.; n=1; Takifugu rubripes|Rep: Homolog of Homo
sapiens "AKR1B1 protein. - Takifugu rubripes
Length = 330
Score = 113 bits (271), Expect = 5e-24
Identities = 57/123 (46%), Positives = 76/123 (61%)
Frame = +3
Query: 132 VPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETE 311
+PS+ +N G MP +GLGT+ KS + V AI GYRH DTA VYE E
Sbjct: 2 IPSVTLNTGALMPVLGLGTW---------KSGKGVTTEAVKVAIGAGYRHIDTAYVYENE 52
Query: 312 QEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHW 491
E+G V+ +++GVVKRE++FI +KLW T H + V A +L L LDY+DLYLMH+
Sbjct: 53 TEVGAGVQAMIDQGVVKREELFIVSKLWCTFHTPSLVRGACEKTLSSLNLDYVDLYLMHF 112
Query: 492 PIG 500
P+G
Sbjct: 113 PMG 115
Score = 45.2 bits (102), Expect = 0.001
Identities = 18/40 (45%), Positives = 27/40 (67%)
Frame = +3
Query: 534 FMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIK 653
F++TW +E+ G+ K IG+SNFNK Q+E VL + +K
Sbjct: 162 FLDTWEAMEELVDDGLAKAIGISNFNKDQIEAVLNKPGLK 201
>UniRef50_Q7WSY4 Cluster: Putative aldo-keto reductase; n=1;
Propionibacterium freudenreichii subsp. shermanii|Rep:
Putative aldo-keto reductase - Propionibacterium
freudenreichii subsp. shermanii
Length = 280
Score = 113 bits (271), Expect = 5e-24
Identities = 62/174 (35%), Positives = 97/174 (55%)
Frame = +3
Query: 123 TMEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVY 302
T P+++++ G MP +G+GT+ K ++ R V AI+ GYR DTA Y
Sbjct: 5 TTPTPTVELSGGTRMPMLGMGTW---------PLKGEECRAAVASAIEQGYRLVDTAEAY 55
Query: 303 ETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYL 482
E+ +G+AV+ E R +IF+TTK H R V +A+ SL++LGLDY+DL+L
Sbjct: 56 GNEEAVGKAVR----EAGPDRAEIFVTTKFSKQWHSRKGVHEALEHSLERLGLDYVDLFL 111
Query: 483 MHWPIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEG 644
MHWP+ Y ++ +RG+ + + G+ K IG+SNF L+ ++ EG
Sbjct: 112 MHWPMPGEGSY-------VDAYRGMVELKEQGLAKAIGVSNFKVHHLDDLITEG 158
>UniRef50_Q9HGY0 Cluster: Glycerol dehydrogenase; n=8;
Saccharomycetaceae|Rep: Glycerol dehydrogenase -
Zygosaccharomyces rouxii (Candida mogii)
Length = 310
Score = 113 bits (271), Expect = 5e-24
Identities = 68/190 (35%), Positives = 105/190 (55%), Gaps = 18/190 (9%)
Frame = +3
Query: 138 SLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 317
+LK+N G+ +P +GLGT+ +SK+ + V+ A+ GYRH D A+VY E E
Sbjct: 10 TLKLNTGQTIPQVGLGTW---------RSKENEGYKAVIEALKAGYRHIDGAAVYGNEGE 60
Query: 318 IGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 497
+G+A+ ++ V R +IF+TTKLW T R + +A++ SL++LGLDY+ LYL+HWP+
Sbjct: 61 VGKAI----QDSGVPRNEIFLTTKLWCTHQRNPQ--EALDQSLQRLGLDYVGLYLVHWPV 114
Query: 498 GLNADY--------------SHSDVD----FMETWRGLEDAQRMGIVKGIGLSNFNKQQL 623
L + DVD F++TW ++ G K IG+SNF+ L
Sbjct: 115 PLRTENIKDGNLFQFAEKPDGSKDVDLEWNFIKTWELMQKLLESGKTKAIGVSNFSVNNL 174
Query: 624 ERVLKEGTIK 653
+ +L T K
Sbjct: 175 KDLLAAPTTK 184
>UniRef50_P38715 Cluster: NADPH-dependent aldose reductase GRE3;
n=39; cellular organisms|Rep: NADPH-dependent aldose
reductase GRE3 - Saccharomyces cerevisiae (Baker's
yeast)
Length = 327
Score = 113 bits (271), Expect = 5e-24
Identities = 67/194 (34%), Positives = 102/194 (52%), Gaps = 21/194 (10%)
Frame = +3
Query: 147 MNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGE 326
+NNG MP +GLG + K K + + AI +GYR FD A Y E+E+GE
Sbjct: 7 LNNGLKMPLVGLGCW---------KIDKKVCANQIYEAIKLGYRLFDGACDYGNEKEVGE 57
Query: 327 AVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL- 503
++ + EG+V R+DIF+ +KLWN H V A+ +L +GLDY+DLY +H+PI
Sbjct: 58 GIRKAISEGLVSRKDIFVVSKLWNNFHHPDHVKLALKKTLSDMGLDYLDLYYIHFPIAFK 117
Query: 504 --------------NAD------YSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQL 623
AD + + V ++T+R LE+ G++K IG+SNF +
Sbjct: 118 YVPFEEKYPPGFYTGADDEKKGHITEAHVPIIDTYRALEECVDEGLIKSIGVSNFQGSLI 177
Query: 624 ERVLKEGTIKPDAI 665
+ +L+ IKP A+
Sbjct: 178 QDLLRGCRIKPVAL 191
>UniRef50_Q9ZBW7 Cluster: Putative oxidoreductase; n=2;
Actinomycetales|Rep: Putative oxidoreductase -
Streptomyces coelicolor
Length = 277
Score = 112 bits (270), Expect = 6e-24
Identities = 62/176 (35%), Positives = 97/176 (55%)
Frame = +3
Query: 129 EVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYET 308
+VP + +NNG +MP +G G + + D + V A++ GYR DTA++Y
Sbjct: 4 KVPPIILNNGVEMPQLGFGVW---------QVPDDDAQTAVALALEAGYRSIDTAAIYGN 54
Query: 309 EQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMH 488
E+ G A+ G+ RED+F+TTKLWN+ +A + S+ KLGL+Y+DLYL+H
Sbjct: 55 EEGTGRAI---AASGLA-REDLFVTTKLWNSDQGYDSTLRAFDTSMAKLGLEYLDLYLIH 110
Query: 489 WPIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
WP+ Y ++T++ E G V+ IG+SNF + LER+ E ++ P
Sbjct: 111 WPMPAKERY-------VDTYKAFEKLLADGRVRAIGVSNFLPEHLERLTAETSVIP 159
>UniRef50_A7ALH6 Cluster: Putative uncharacterized protein; n=1;
Parabacteroides merdae ATCC 43184|Rep: Putative
uncharacterized protein - Parabacteroides merdae ATCC
43184
Length = 301
Score = 112 bits (269), Expect = 8e-24
Identities = 68/176 (38%), Positives = 100/176 (56%)
Frame = +3
Query: 129 EVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYET 308
+VP++K+NNG +MP +G+GT+L D + V AI VG+R DTA Y
Sbjct: 28 KVPTVKLNNGMEMPQLGVGTFLVKDNAA----------ERVCHAIKVGFRLIDTAQGYGN 77
Query: 309 EQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMH 488
E+E+GE + G+ +RE +FITTK+ + R V Q+++ SL LG DYIDL L+H
Sbjct: 78 EKEVGEGI---CRSGIDRRE-LFITTKVNTMEMRGGTVRQSLDKSLADLGTDYIDLVLIH 133
Query: 489 WPIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
WP+ H ETW+ LE+ G ++ IG+SNFN L+ +L+ I+P
Sbjct: 134 WPV-----KGH----IKETWQILEEYVDKGKIRSIGVSNFNPHHLDELLEYARIRP 180
>UniRef50_Q6CEJ0 Cluster: Yarrowia lipolytica chromosome B of strain
CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome B of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 302
Score = 112 bits (269), Expect = 8e-24
Identities = 67/178 (37%), Positives = 105/178 (58%), Gaps = 1/178 (0%)
Frame = +3
Query: 126 MEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYE 305
M VP +K++NG ++PAIG G+ + + K ++++L D V+ AI+ G+ H DTA Y
Sbjct: 1 MTVPKVKLSNGLEIPAIGFGSGTKWKRPPGEK-EERELIDAVVSAINAGHLHIDTAEFYG 59
Query: 306 TEQEIGEAVKMKVEEGVVKREDIFITTK-LWNTQHRRTEVAQAINDSLKKLGLDYIDLYL 482
TE++IGEA+K E V R+DIF+T+K L+ + ++I++ LK L DY DL+L
Sbjct: 60 TEKQIGEAIK----ESGVPRKDIFLTSKTLFGL--LADDPIESISNQLKTLQTDYFDLFL 113
Query: 483 MHWPIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
+H P + +Y D + W LE G+ K IG+SN + +LE ++K IKP
Sbjct: 114 IHVPPNDDINY-----DLAKAWGVLEQLYEKGLAKAIGVSNHSPAELETIIKVAKIKP 166
>UniRef50_A6LZ55 Cluster: 2,5-didehydrogluconate reductase; n=1;
Clostridium beijerinckii NCIMB 8052|Rep:
2,5-didehydrogluconate reductase - Clostridium
beijerinckii NCIMB 8052
Length = 289
Score = 111 bits (268), Expect = 1e-23
Identities = 60/172 (34%), Positives = 94/172 (54%)
Frame = +3
Query: 141 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 320
+K NG +P +G G Y +K + V AI +GYRHFDTA +Y E+++
Sbjct: 8 IKAVNGIKIPQVGFGVYK--------LNKGEDFETAVGEAIKIGYRHFDTAKIYGNEKDL 59
Query: 321 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 500
G A+ E+ + RE+ FIT+K+WNT H +A + KKL ++Y+D+YL+H+
Sbjct: 60 GLAI----EKSQIPREEFFITSKVWNTDHGYEATKKAFEQTCKKLNVEYLDMYLIHFA-- 113
Query: 501 LNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
+ Y ++ETW +E+ G +K IG++NF Q LE ++K I P
Sbjct: 114 --SSY------YLETWHAMEELYLQGKIKVIGVANFQIQHLEELMKHSRITP 157
>UniRef50_Q1IN88 Cluster: Aldehyde reductase; n=5; Bacteria|Rep:
Aldehyde reductase - Acidobacteria bacterium (strain
Ellin345)
Length = 313
Score = 111 bits (267), Expect = 1e-23
Identities = 64/179 (35%), Positives = 92/179 (51%), Gaps = 12/179 (6%)
Frame = +3
Query: 165 MPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKV 344
+PA+G GT + + ++D A+ G+RHFD A Y E+E+GEA++
Sbjct: 20 IPALGFGTLIADPALTITATRD---------ALAAGFRHFDCAERYRNEREVGEALRAGR 70
Query: 345 EEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL------- 503
G + RE+IF+TTKLWNT HR V A SL +LGLDY+DLYL+H P
Sbjct: 71 AAGNIAREEIFVTTKLWNTNHRPERVEPAFEASLDRLGLDYLDLYLIHTPFAFQPGDEQD 130
Query: 504 ----NADYSHSD-VDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAI 665
N + + V ETW LE+ G + IGLS+ + +L + + IKP +
Sbjct: 131 PRDQNGSVIYDEGVTLRETWSALENLVDRGRCRAIGLSDISMDRLAPIYEAARIKPAVV 189
>UniRef50_A3JU52 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=1; Rhodobacterales bacterium HTCC2150|Rep:
2,5-diketo-D-gluconic acid reductase A - Rhodobacterales
bacterium HTCC2150
Length = 334
Score = 111 bits (267), Expect = 1e-23
Identities = 66/194 (34%), Positives = 98/194 (50%), Gaps = 7/194 (3%)
Frame = +3
Query: 102 NLTELASTMEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRH 281
N TE T + +N +PA+G GTYL + + D + + AI GYRH
Sbjct: 27 NGTEHPMTNTATTFTLNTTTTIPAVGFGTYL-------ISNDDA--KSTISAAIQAGYRH 77
Query: 282 FDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLW-------NTQHRRTEVAQAIND 440
DTAS Y+ E+ +G +K ++ + R+D+F+T KLW + + + +
Sbjct: 78 IDTASGYQNEKTVGAGIKAGLQSAGITRKDLFVTAKLWPGNPAWGDAPKTKAQTLDECDA 137
Query: 441 SLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQ 620
SL +LGLDY+DLYL+H P G D+ +E WR L + Q G + IG+SNFN+
Sbjct: 138 SLARLGLDYVDLYLIHAPYG-------GDMR-LEQWRALLELQANGKARSIGVSNFNESH 189
Query: 621 LERVLKEGTIKPDA 662
L + G PDA
Sbjct: 190 LNEIKAAGLPMPDA 203
>UniRef50_P23901 Cluster: Aldose reductase; n=9; Poaceae|Rep: Aldose
reductase - Hordeum vulgare (Barley)
Length = 320
Score = 111 bits (267), Expect = 1e-23
Identities = 62/178 (34%), Positives = 97/178 (54%), Gaps = 8/178 (4%)
Frame = +3
Query: 147 MNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGE 326
+ +G MPA+GLGT+ ++ V + GYRH DTA+ Y E+E+G+
Sbjct: 18 LKSGHAMPAVGLGTW---------RAGSDTAHSVRTAITEAGYRHVDTAAEYGVEKEVGK 68
Query: 327 AVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLN 506
+K +E G+ R+D+F+T+K+W T V A+ ++LK L LDYIDLY +HWP L
Sbjct: 69 GLKAAMEAGI-DRKDLFVTSKIWCTNLAPERVRPALENTLKDLQLDYIDLYHIHWPFRLK 127
Query: 507 ADYSHS--------DVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
D +H + D W+ +E+ + G+VK IG+ N+ +L R+L+ I P
Sbjct: 128 -DGAHMPPEAGEVLEFDMEGVWKEMENLVKDGLVKDIGVCNYTVTKLNRLLRSAKIPP 184
>UniRef50_Q8EUH6 Cluster: Oxidoreductase; n=1; Mycoplasma
penetrans|Rep: Oxidoreductase - Mycoplasma penetrans
Length = 285
Score = 111 bits (266), Expect = 2e-23
Identities = 67/173 (38%), Positives = 94/173 (54%), Gaps = 1/173 (0%)
Frame = +3
Query: 141 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAID-VGYRHFDTASVYETEQE 317
+K+ NG MP IGLG Y K++ + + +++AID GYR DTA VY E+
Sbjct: 4 IKLANGLHMPIIGLGVY---------KAEGENCENTIIKAIDDYGYRMIDTAQVYFNEEF 54
Query: 318 IGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 497
+G A+K + +KREDIFITTK+W + + +I+ SLKKL +YIDL L+H P
Sbjct: 55 VGNAIK----QTKIKREDIFITTKVWISNYGYNNTMYSISKSLKKLQTNYIDLVLLHQPF 110
Query: 498 GLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
G D+ W+ LE + GIVK IG+SNF +L +KP
Sbjct: 111 G----------DYYSAWKALEVLYKKGIVKAIGVSNFEADRLVDFCLHVDVKP 153
>UniRef50_Q83N50 Cluster: 2,5-diketo-D-gluconic acid reductase; n=2;
Tropheryma whipplei|Rep: 2,5-diketo-D-gluconic acid
reductase - Tropheryma whipplei (strain Twist)
(Whipple's bacillus)
Length = 283
Score = 111 bits (266), Expect = 2e-23
Identities = 62/171 (36%), Positives = 96/171 (56%)
Frame = +3
Query: 132 VPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETE 311
VPS+ + +G +P GLGTY + + VV AI++GYRH DTAS+Y E
Sbjct: 9 VPSVLLGDGVSIPQFGLGTY---------ELPPNEASSVVQSAIELGYRHIDTASLYANE 59
Query: 312 QEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHW 491
+E+G A+ G +KRE+ F+TTKLWN+ + +A SL L LDY+DLYL+HW
Sbjct: 60 REVGRAI---ASSG-IKREEFFVTTKLWNSDQPKPR--EAFERSLDLLSLDYVDLYLIHW 113
Query: 492 PIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEG 644
P S++ ++ W L + + G K +G+SNF + ++++ + G
Sbjct: 114 PC------PPSEL-YINVWEVLLELKESGRAKSVGVSNFLSEHIDKIKEAG 157
>UniRef50_Q4PAT5 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 700
Score = 111 bits (266), Expect = 2e-23
Identities = 70/197 (35%), Positives = 103/197 (52%), Gaps = 17/197 (8%)
Frame = +3
Query: 117 ASTMEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTAS 296
+S + + NG +P +G GT+ K +Q V AI GYRH D A
Sbjct: 4 SSVRRSANFTLANGAQIPKLGFGTW---------KMSKEQATPAVAHAIKTGYRHIDCAW 54
Query: 297 VYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDL 476
Y E +AV +++ V R +++T+KLWN+ H V +A++ SLK LG DY+DL
Sbjct: 55 AYRNE----DAVAAGIKKAGVPRSQLWLTSKLWNSFHHPEHVEKALDASLKDLGTDYLDL 110
Query: 477 YLMHWPIG-LNADYS--------------HSDV--DFMETWRGLEDAQRMGIVKGIGLSN 605
YLMHWP+ LN+ S D+ DFM T+R +E+ + G V+ IG+SN
Sbjct: 111 YLMHWPVAFLNSKGSMVPSIRSTGGHPVESEDLSRDFMATYRVMEEMVKKGKVRNIGVSN 170
Query: 606 FNKQQLERVLKEGTIKP 656
FN ++ V+ E +IKP
Sbjct: 171 FNIRRTSEVVDEASIKP 187
>UniRef50_Q6F7K7 Cluster: 2,5-diketo-D-gluconate reductase; n=20;
Bacteria|Rep: 2,5-diketo-D-gluconate reductase -
Acinetobacter sp. (strain ADP1)
Length = 297
Score = 110 bits (265), Expect = 3e-23
Identities = 63/175 (36%), Positives = 99/175 (56%)
Frame = +3
Query: 132 VPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETE 311
+P L +++G +PA+G GTY Q GV D ++RA+ GYR D+A YE E
Sbjct: 22 IPDLILHDGHSIPALGFGTYTLKGQQGV---------DTMLRALGHGYRMLDSAFNYENE 72
Query: 312 QEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHW 491
+G AV+ + G++ R++IFIT+KL H + + I +SL ++ DY+DLYL+HW
Sbjct: 73 GAVGAAVR---QSGLL-RDEIFITSKLPGRHHAYDKAMETIEESLYRMQFDYLDLYLIHW 128
Query: 492 PIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
P Y +E W+ L DAQ+ G ++ IG+SNF + +E + +E + P
Sbjct: 129 PNPQQGLY-------IEAWQALIDAQKKGYIRSIGVSNFLPKHIETLRRETGVIP 176
>UniRef50_Q6RZX1 Cluster: Gld1; n=22; Pezizomycotina|Rep: Gld1 -
Trichoderma atroviride (Hypocrea atroviridis)
Length = 327
Score = 110 bits (265), Expect = 3e-23
Identities = 68/194 (35%), Positives = 102/194 (52%), Gaps = 16/194 (8%)
Frame = +3
Query: 123 TMEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVY 302
T+ + +N G +PA+G GT+ G + V +A+DVGYRH D A Y
Sbjct: 9 TLSSTTYTLNTGAKIPAVGFGTFANEGAKGETYA-------AVTKALDVGYRHLDCAWFY 61
Query: 303 ETEQEIGEAVK-MKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLY 479
E E+G+A++ V R+D+FI TK+WN H +V + +S + L +DYIDL+
Sbjct: 62 LNEDEVGDAIRDFLARRPDVTRKDLFICTKVWNHLHEPEDVKWSAKNSCENLKVDYIDLF 121
Query: 480 LMHWPIGL--NADYS---HSDVDFM----------ETWRGLEDAQRMGIVKGIGLSNFNK 614
L+HWPI NAD + D ++ TWR +E+ GIVK IG+SN+
Sbjct: 122 LVHWPIAAEKNADRTVKIGPDGKYVINKALTENPEPTWRAMEELVDSGIVKAIGVSNWTI 181
Query: 615 QQLERVLKEGTIKP 656
L+++L+ IKP
Sbjct: 182 PGLKQLLEFARIKP 195
>UniRef50_P47137 Cluster: Probable oxidoreductase YJR096W; n=8;
Saccharomycetales|Rep: Probable oxidoreductase YJR096W -
Saccharomyces cerevisiae (Baker's yeast)
Length = 282
Score = 110 bits (265), Expect = 3e-23
Identities = 65/173 (37%), Positives = 99/173 (57%), Gaps = 3/173 (1%)
Frame = +3
Query: 144 KMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIG 323
K++NG +P+I LGTY + +S Q ++V + GYRHFDTA +Y E+E+G
Sbjct: 7 KLSNGFKIPSIALGTY------DIPRS---QTAEIVYEGVKCGYRHFDTAVLYGNEKEVG 57
Query: 324 EAVKMKVEE--GVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKL-GLDYIDLYLMHWP 494
+ + + E G KRE+IF TTKLWN+Q+ AI L ++ GL YIDL L+H P
Sbjct: 58 DGIIKWLNEDPGNHKREEIFYTTKLWNSQNGYKRAKAAIRQCLNEVSGLQYIDLLLIHSP 117
Query: 495 IGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIK 653
+ +ETWR +++A G+VK IG+SN+ K+ ++ +L +K
Sbjct: 118 L-------EGSKLRLETWRAMQEAVDEGLVKSIGVSNYGKKHIDELLNWPELK 163
>UniRef50_UPI0000D9A956 Cluster: PREDICTED: similar to aldo-keto
reductase family 1, member B10, partial; n=1; Macaca
mulatta|Rep: PREDICTED: similar to aldo-keto reductase
family 1, member B10, partial - Macaca mulatta
Length = 275
Score = 110 bits (264), Expect = 3e-23
Identities = 61/151 (40%), Positives = 88/151 (58%), Gaps = 6/151 (3%)
Frame = +3
Query: 219 KSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK--- 389
KS ++++ V AID GYRH D A VY+ E E+GEA++ K++E VKRED+FI +K
Sbjct: 42 KSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEQAVKREDLFIVSKVHM 101
Query: 390 ---LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLE 560
LW T R V +A +LK L L Y+D+YL+HWP G A +E
Sbjct: 102 AHWLWTTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKA---------------ME 146
Query: 561 DAQRMGIVKGIGLSNFNKQQLERVLKEGTIK 653
+ G+VK +G+SNFN Q+E++L + +K
Sbjct: 147 ELVDEGLVKALGISNFNHFQIEKLLNKPGLK 177
>UniRef50_Q9X265 Cluster: Oxidoreductase, aldo/keto reductase
family; n=2; Thermotoga|Rep: Oxidoreductase, aldo/keto
reductase family - Thermotoga maritima
Length = 274
Score = 110 bits (264), Expect = 3e-23
Identities = 59/167 (35%), Positives = 103/167 (61%), Gaps = 5/167 (2%)
Frame = +3
Query: 156 GRDMPAIGLGTYL--GFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVY---ETEQEI 320
G ++PA+GLGT+ GF+ S+D+++ +++ AI +GY H DTA Y TE+ I
Sbjct: 10 GEEIPALGLGTWGIGGFETPDY--SRDEEMVELLKTAIKMGYTHIDTAEYYGGGHTEELI 67
Query: 321 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 500
G+A+K +RED+FI +K+W T RR ++ +++ ++LK+L DY+DLYL+HWP
Sbjct: 68 GKAIKD------FRREDLFIVSKVWPTHLRRDDLLRSLENTLKRLDTDYVDLYLIHWP-- 119
Query: 501 LNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKE 641
+ ++ ET + + R G+++ IG+SNF+++ LE + +
Sbjct: 120 ------NPEIPLEETLSAMAEGVRQGLIRYIGVSNFDRRLLEEAISK 160
>UniRef50_Q7VG53 Cluster: Aldo-keto reductase; n=28; Bacteria|Rep:
Aldo-keto reductase - Helicobacter hepaticus
Length = 292
Score = 110 bits (264), Expect = 3e-23
Identities = 71/176 (40%), Positives = 101/176 (57%), Gaps = 4/176 (2%)
Frame = +3
Query: 147 MNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGE 326
+NNG +P +GLGT+ D N VV++ V A VGYRH DTA Y E+ +GE
Sbjct: 17 LNNGNKIPKLGLGTWR-IDDN-VVEA-------AVREAFKVGYRHIDTAQAYGNERGVGE 67
Query: 327 AVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLN 506
AV+ + +KRE++FIT+K+ + +I+ SLK + LD+IDL L+H P N
Sbjct: 68 AVR----KSKIKREELFITSKIRAEYKDYKSASASIDTSLKTMKLDFIDLMLIHSPQPWN 123
Query: 507 A----DYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDA 662
+ DY +V E + LEDAQ+ G V+ IG+SNF ++ LE +LK KP A
Sbjct: 124 SFRKGDYFKENV---EVYNALEDAQKAGKVRSIGVSNFLQKDLENILKNCKTKPAA 176
>UniRef50_Q17G72 Cluster: Aldo-keto reductase; n=9;
Endopterygota|Rep: Aldo-keto reductase - Aedes aegypti
(Yellowfever mosquito)
Length = 316
Score = 110 bits (264), Expect = 3e-23
Identities = 61/183 (33%), Positives = 101/183 (55%), Gaps = 11/183 (6%)
Frame = +3
Query: 141 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 320
+ NG MPA+G GT+ ++ D+++ + A++ GYRH DTA VY E+ I
Sbjct: 7 ITFENGTTMPALGFGTW---------RASDEEVEKALNEALEAGYRHIDTAPVYLNEKTI 57
Query: 321 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI- 497
G+ +K ++ G V R+++FI TKL R + V + + +SL L L+Y+DLY +H P
Sbjct: 58 GKVLKEWMDAGKVTRDELFIVTKLPPHGTRASTVEKFLKNSLDDLQLEYVDLYHVHVPFT 117
Query: 498 --GLNADYSHSD--------VDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGT 647
++ + D D + W+ +E+ G+ + IGLSNFN++Q++R+L
Sbjct: 118 VPEVDGPFLVEDGLIVLETTTDHVALWKAMEEVYEAGLARNIGLSNFNQRQIQRILDNCQ 177
Query: 648 IKP 656
IKP
Sbjct: 178 IKP 180
>UniRef50_O13848 Cluster: NADH/NADPH dependent indole-3-acetaldehyde
reductase AKR3C2; n=1; Schizosaccharomyces pombe|Rep:
NADH/NADPH dependent indole-3-acetaldehyde reductase
AKR3C2 - Schizosaccharomyces pombe (Fission yeast)
Length = 284
Score = 109 bits (262), Expect = 6e-23
Identities = 62/164 (37%), Positives = 92/164 (56%)
Frame = +3
Query: 165 MPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKV 344
+PA G+GT L + G + ++ + D V A+ G+ H D A VY E+E+G A+K
Sbjct: 12 VPAYGVGTALFKKEKGEI---NRTIVDSVKNALAAGFIHIDCAEVYGNEEEVGVALK--- 65
Query: 345 EEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHS 524
E V R +FIT+K+ H + +A+N+SL+KLG DY+DLYL+H PI +
Sbjct: 66 -EANVPRSKLFITSKV---MHNVDNIPEALNESLRKLGTDYLDLYLLHSPI----PFYEK 117
Query: 525 DVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
+ E W+ +E A G+V +G+SNF LE +LK TI P
Sbjct: 118 KIPISEGWKAMETALGTGLVHSVGVSNFRIPDLEELLKTSTITP 161
>UniRef50_Q5FLI5 Cluster: Aldehyde reductase; n=2; Bacteria|Rep:
Aldehyde reductase - Lactobacillus acidophilus
Length = 278
Score = 109 bits (261), Expect = 8e-23
Identities = 65/170 (38%), Positives = 92/170 (54%)
Frame = +3
Query: 147 MNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGE 326
+NNG MP +G G Y D Q + VV ++VGYR DTA +Y EQ +G+
Sbjct: 7 LNNGIKMPRLGFGVYQIDDL--------AQAQQVVEDGLEVGYRLVDTAQIYGNEQAVGD 58
Query: 327 AVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLN 506
A+K V REDIFIT+K+W + +A +DS+KKL LDYIDLYL+H P
Sbjct: 59 AIK----HSNVPREDIFITSKIWVDDYGYDNTLKAFDDSMKKLQLDYIDLYLIHKPYN-- 112
Query: 507 ADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
D+ TWR LE + G ++ IG+S+F ++L ++ +KP
Sbjct: 113 --------DYYGTWRALERLYQEGRIRAIGVSSFWNERLADLITFNDVKP 154
>UniRef50_Q043M4 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=2; Lactobacillus|Rep: Aldo/keto
reductase of diketogulonate reductase family -
Lactobacillus gasseri (strain ATCC 33323 / DSM 20243)
Length = 273
Score = 109 bits (261), Expect = 8e-23
Identities = 61/172 (35%), Positives = 96/172 (55%)
Frame = +3
Query: 141 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 320
L +NN +P G GTY + Q + V+ A + GYR DTA Y+ EQ++
Sbjct: 4 LTLNNDVKIPIFGFGTY---------EISPDQTKQAVLSAFEEGYRLIDTAQYYQNEQQV 54
Query: 321 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 500
GEAVK + R+++FITTK + T++ +++SL+++GLDY DL L+HWP+G
Sbjct: 55 GEAVKASG----LNRDEVFITTKTMTDGYEDTKIG--LDESLRRIGLDYFDLVLIHWPMG 108
Query: 501 LNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
D+D TW LE A + G + IG+SNFN +Q ++ + +++P
Sbjct: 109 -------HDID---TWHALEAAYKAGKTRAIGISNFNSRQTLDLIHQSSVRP 150
>UniRef50_Q24C22 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=4; Oligohymenophorea|Rep: Oxidoreductase,
aldo/keto reductase family protein - Tetrahymena
thermophila SB210
Length = 297
Score = 109 bits (261), Expect = 8e-23
Identities = 61/182 (33%), Positives = 101/182 (55%), Gaps = 4/182 (2%)
Frame = +3
Query: 126 MEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYE 305
++VP L G +P IG GTY QN + V A+ +GY H DTASVY
Sbjct: 11 VKVPILNFREGGSIPQIGYGTY-ELRQNDCIIG--------VTEALKIGYTHIDTASVYR 61
Query: 306 TEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLM 485
EQ+I + + +KRED+FIT+K+ + + +A+ D L +L + Y+D L+
Sbjct: 62 NEQDIAKVIHNPAYG--IKREDLFITSKISPGEQGYEQAKKAVQDMLTRLNIKYLDCVLI 119
Query: 486 HWPIGLNA----DYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIK 653
HWP G++ D ++ + +ETW+ L + ++ G++K IG+SNFN L+ ++++ K
Sbjct: 120 HWP-GVSKLPPNDPKNAQIR-LETWKALIELRKAGVIKHIGVSNFNINHLQHLIEKSEFK 177
Query: 654 PD 659
P+
Sbjct: 178 PE 179
>UniRef50_Q5XJM7 Cluster: Zgc:101765; n=5; Eumetazoa|Rep: Zgc:101765
- Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 288
Score = 108 bits (259), Expect = 1e-22
Identities = 61/176 (34%), Positives = 96/176 (54%), Gaps = 2/176 (1%)
Frame = +3
Query: 135 PSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQ 314
PS+ +NN MP +GLGT+ Q + D L+ GYR FDTA+VY E
Sbjct: 6 PSVLLNNDIQMPLLGLGTFRLQGQEDTYSAVDAALK--------AGYRAFDTAAVYRNEA 57
Query: 315 EIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 494
+G A++ + + + RED+FIT+KL + + ++ SL++LGL YIDLYL+HWP
Sbjct: 58 HLGHALRCLLPKHGLSREDVFITSKL-GPKDQGSKARNGCQKSLEQLGLGYIDLYLIHWP 116
Query: 495 --IGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
GL + + ++WR LE+ G + IG+SN+ + ++ +LK + P
Sbjct: 117 GTQGLPVGDKRNPENRAQSWRVLEEFYSEGKFRAIGVSNYTVEHMQELLKSCKVPP 172
>UniRef50_Q1RFP0 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=21; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase
A - Escherichia coli (strain UTI89 / UPEC)
Length = 294
Score = 108 bits (259), Expect = 1e-22
Identities = 62/151 (41%), Positives = 84/151 (55%), Gaps = 2/151 (1%)
Frame = +3
Query: 210 GVVKSKDKQL-RDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITT 386
GV + DK + + V+ AI GYR DTA+VY E +GEAV+ + EG+ RE++FIT+
Sbjct: 23 GVFQVTDKDVCKQSVLNAIRTGYRLIDTAAVYGNEDAVGEAVREAISEGLCTREELFITS 82
Query: 387 KLWNTQHRRTEVAQA-INDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLED 563
KLW ++A A I SLKK GL+Y DLYL+H + D+ WR LED
Sbjct: 83 KLWVQDMLNQDIAAAGIEASLKKSGLEYFDLYLLHQAMR----------DYFSAWRALED 132
Query: 564 AQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
A G +K IG+SNF L + +KP
Sbjct: 133 AYEEGKLKAIGVSNFYPHVLANFCETVRVKP 163
>UniRef50_A7PNI3 Cluster: Chromosome chr1 scaffold_22, whole genome
shotgun sequence; n=2; Vitis vinifera|Rep: Chromosome
chr1 scaffold_22, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 360
Score = 108 bits (259), Expect = 1e-22
Identities = 67/182 (36%), Positives = 100/182 (54%), Gaps = 12/182 (6%)
Frame = +3
Query: 147 MNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGE 326
+N +PAIGLGT+ +S + V RA+ GYR D A +Y E E+GE
Sbjct: 14 LNTKAKIPAIGLGTW---------QSGGDLCVEAVKRALSEGYRQIDCAHLYGNEVEVGE 64
Query: 327 AVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP---- 494
A+ + G +KRED+F+T+KL+ T + ++ ++ SLK LG+ Y+DLYLMHWP
Sbjct: 65 ALA-EAFNGSLKREDVFLTSKLYCTMNSLNKIENSVRVSLKNLGVTYLDLYLMHWPDITA 123
Query: 495 IGLNAD-YSHSDVD-------FMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTI 650
G D S+S D + W+ +E +G+V+ IG+SNF QQ++ +LK I
Sbjct: 124 FGDATDPPSNSGNDHRQFLNRLKKAWKAMEGLIELGLVRAIGVSNFGVQQIKELLKFAKI 183
Query: 651 KP 656
P
Sbjct: 184 VP 185
>UniRef50_Q5T2L2 Cluster: Aldo-keto reductase family 1 member C-like
protein 1; n=14; Eutheria|Rep: Aldo-keto reductase
family 1 member C-like protein 1 - Homo sapiens (Human)
Length = 302
Score = 107 bits (258), Expect = 2e-22
Identities = 54/122 (44%), Positives = 79/122 (64%)
Frame = +3
Query: 138 SLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 317
S+++N+G MP +G GTY + KS+ + V AIDVG+RH D+A +Y+ E+E
Sbjct: 10 SVRLNDGPFMPVLGFGTYA---PDHTPKSQAAEATKV---AIDVGFRHIDSAYLYQNEEE 63
Query: 318 IGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 497
+G+A+ K+ +G VKRE+IF T KLW T R V A+ SLKKLG DY+DL+++H P
Sbjct: 64 VGQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVPF 123
Query: 498 GL 503
+
Sbjct: 124 AM 125
>UniRef50_Q0CLQ2 Cluster: Putative uncharacterized protein; n=1;
Aspergillus terreus NIH2624|Rep: Putative
uncharacterized protein - Aspergillus terreus (strain
NIH 2624)
Length = 301
Score = 107 bits (257), Expect = 2e-22
Identities = 70/206 (33%), Positives = 104/206 (50%), Gaps = 33/206 (16%)
Frame = +3
Query: 138 SLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 317
S K+++G DMPA+GLGT+L SK ++ + V A+ +GYRH D A+ Y E E
Sbjct: 6 SFKLSSGYDMPAVGLGTWL---------SKPHEVENAVETALRLGYRHIDAAACYLNENE 56
Query: 318 IGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYL----- 482
+G K + V R+ IFIT+KLWNT H V +A+N +LK L DY+DLYL
Sbjct: 57 VGNGWK----KSGVPRDQIFITSKLWNTHHHPDHVEEAVNKTLKDLQTDYLDLYLVFPSL 112
Query: 483 ---------------MHWPIG-------------LNADYSHSDVDFMETWRGLEDAQRMG 578
+HWP+ ++ + +++ +TW LE G
Sbjct: 113 LVLIHDLLSLLTNNKIHWPVAFEHTNETLTPIDPVSKRFRLANIPIADTWAALEKLVDAG 172
Query: 579 IVKGIGLSNFNKQQLERVLKEGTIKP 656
V+ IG+SNF +++E +LK I P
Sbjct: 173 KVRSIGVSNFTIEKIEELLKTARIPP 198
>UniRef50_A2QVE5 Cluster: Similarity: shows similarity to several
dehydrogenases of different specificities; n=4;
Pezizomycotina|Rep: Similarity: shows similarity to
several dehydrogenases of different specificities -
Aspergillus niger
Length = 381
Score = 107 bits (257), Expect = 2e-22
Identities = 61/188 (32%), Positives = 102/188 (54%), Gaps = 18/188 (9%)
Frame = +3
Query: 147 MNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGE 326
+N+G +P +G GT+ +S Q+ D V A+ GYRH D A++Y+ ++E+ E
Sbjct: 9 LNSGAQIPQLGFGTW---------QSAPGQVGDAVYEALKAGYRHLDLATIYQNQREVAE 59
Query: 327 AVKMKVEEGV-VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG- 500
+K ++ +KREDIFIT+KLWN+QH V +A+++ L +L LDY+DLYL+HWP+
Sbjct: 60 GIKRAYKDVPGLKREDIFITSKLWNSQHDPAVVEKALDECLAELELDYLDLYLVHWPVSF 119
Query: 501 --------LNADYS--------HSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERV 632
L D S + D+ ++TW+ + + + +G+SN LE +
Sbjct: 120 TTGSELFPLVKDSSVEGGDVVINDDISIVDTWKAMTQLPK-SKARTVGVSNHMIPHLEAI 178
Query: 633 LKEGTIKP 656
+ + P
Sbjct: 179 INATGVVP 186
>UniRef50_Q03X85 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=1; Leuconostoc mesenteroides subsp.
mesenteroides ATCC 8293|Rep: Aldo/keto reductase of
diketogulonate reductase family - Leuconostoc
mesenteroides subsp. mesenteroides (strain ATCC 8293
/NCDO 523)
Length = 288
Score = 107 bits (256), Expect = 3e-22
Identities = 62/164 (37%), Positives = 86/164 (52%)
Frame = +3
Query: 147 MNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGE 326
+NNG MP +G G + + ++ + V+ AI+ GYR DTA VY E E G+
Sbjct: 6 LNNGAQMPQLGFGVF---------QIPAEETKQAVVDAINAGYRSIDTARVYGNEAETGQ 56
Query: 327 AVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLN 506
V + VV RE++F+TTKLW ++ AI+DSLKKLG DY DL L+H P G
Sbjct: 57 GVNEAIANAVVAREELFLTTKLWLSEFSYEAAKGAIDDSLKKLGTDYADLILLHQPYG-- 114
Query: 507 ADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLK 638
D ++ L +AQ G VK IG+SNF + +K
Sbjct: 115 --------DVYGAYKALAEAQADGKVKSIGISNFYPAKFVEFIK 150
>UniRef50_Q5FKI1 Cluster: Reductase-dehydrogenase; n=1;
Lactobacillus acidophilus|Rep: Reductase-dehydrogenase -
Lactobacillus acidophilus
Length = 271
Score = 106 bits (255), Expect = 4e-22
Identities = 63/176 (35%), Positives = 97/176 (55%), Gaps = 3/176 (1%)
Frame = +3
Query: 138 SLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 317
S+ +NNG +P I LGT+L + ++ VV +A+++GYR FDTA Y E
Sbjct: 6 SVILNNGEKIPQIQLGTWL---------INNDEVNKVVRQAVNIGYRGFDTAKDYGNESG 56
Query: 318 IGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP- 494
+G+ + ++R DIF+TTKL +AI+ +L K GL+YIDL L+H P
Sbjct: 57 VGKGIW----NSDIERSDIFLTTKLPTAVKDYEGTKKAIDAALDKFGLEYIDLLLIHSPQ 112
Query: 495 --IGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
I +N +E WR +E+A + G V+ IG+SNF ++ +E ++ GTI P
Sbjct: 113 PWIEVNRTNDRHFKGNLENWRAMEEAVKAGKVRSIGVSNFLQEDIENIVNNGTITP 168
>UniRef50_Q8J0K1 Cluster: 4-dihydromethyltrisporate dehydrogenase;
n=2; Parasitella parasitica|Rep:
4-dihydromethyltrisporate dehydrogenase - Parasitella
parasitica
Length = 321
Score = 106 bits (255), Expect = 4e-22
Identities = 62/166 (37%), Positives = 90/166 (54%), Gaps = 17/166 (10%)
Frame = +3
Query: 210 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 389
G K + K + + +AI +GYR FD A Y E E+G + ++EG+VKRE++FI TK
Sbjct: 21 GCWKIEKKDAENTIYQAIKIGYRLFDGACDYGNEVEVGRGINKAIKEGLVKREELFIVTK 80
Query: 390 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLN-----ADY------SHSD-VD 533
LWNT H + V A + LK GL+Y DLYL+H+PI L Y H+D ++
Sbjct: 81 LWNTFHSKQHVRTAFDRQLKDWGLEYFDLYLIHFPIPLQYVDPAVSYPPEWYVPHADKLN 140
Query: 534 F-----METWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
F E W +E + + + IG++NFN Q + +L IKP
Sbjct: 141 FERSPIHECWAEMEKLVQAKLTRNIGVANFNCQAILDLLSYAKIKP 186
>UniRef50_Q5BLA6 Cluster: Zgc:110782; n=2; Danio rerio|Rep:
Zgc:110782 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 287
Score = 106 bits (254), Expect = 5e-22
Identities = 63/179 (35%), Positives = 97/179 (54%), Gaps = 2/179 (1%)
Frame = +3
Query: 126 MEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYE 305
M VPS+++ +G MP +GLGTY D +QL+ V A+ GYR FDTA+VY
Sbjct: 1 MIVPSVRLMSGTQMPLLGLGTYKLQDH--------EQLKQSVSCALQAGYRAFDTAAVYG 52
Query: 306 TEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLM 485
E +G+ +K + + + RED+FI +KL + H + SL++L +YIDLYL+
Sbjct: 53 NEAHLGQVLKELLPKYGLIREDVFIISKLAPSDH-GLRAKEGCLRSLEQLDCEYIDLYLI 111
Query: 486 HWP--IGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
HWP GL+ + S ++W LE+ G K IG+SN+ + + +L + P
Sbjct: 112 HWPGMEGLDPEDSRHSEYRAQSWATLEEFHASGQFKAIGVSNYTAKHIRELLASCRVPP 170
>UniRef50_A0JRJ3 Cluster: 2,5-didehydrogluconate reductase; n=3;
Actinobacteria (class)|Rep: 2,5-didehydrogluconate
reductase - Arthrobacter sp. (strain FB24)
Length = 276
Score = 105 bits (252), Expect = 1e-21
Identities = 61/174 (35%), Positives = 93/174 (53%)
Frame = +3
Query: 135 PSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQ 314
P +++N+G +P IGLGT+ D Q+ V+ A++ GYRH DTA Y E+
Sbjct: 5 PVIELNDGHRIPQIGLGTW---------PLDDHQVAAAVVNAVEGGYRHIDTAVKYGNEK 55
Query: 315 EIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 494
+G ++ + R ++FITTKL + ++ SLK+LGLDY+DL L+HWP
Sbjct: 56 GVGNGIR----SSGLDRSELFITTKLDGEFQGQDRAVAGLDGSLKRLGLDYVDLLLIHWP 111
Query: 495 IGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
+ D +F+ TW+ E Q G V+ IG+SNF LER++ + P
Sbjct: 112 L------PRRD-EFISTWKTFERLQADGKVRSIGVSNFKPAHLERLMAACDVVP 158
>UniRef50_A2EYY6 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=9; Trichomonas vaginalis G3|Rep:
Oxidoreductase, aldo/keto reductase family protein -
Trichomonas vaginalis G3
Length = 308
Score = 105 bits (252), Expect = 1e-21
Identities = 65/172 (37%), Positives = 95/172 (55%), Gaps = 16/172 (9%)
Frame = +3
Query: 165 MPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAI-DVGYRHFDTASVYETEQEIGEAVKMK 341
+P IGLGT+ + + L + + AI + GY H D A YE E +G+A++
Sbjct: 4 IPTIGLGTWKS--------PRSEDLVNAITYAIKEAGYVHIDCALCYENEDIVGQALQQC 55
Query: 342 VEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI-----GLN 506
+ G+ KRE+I+IT+KLWNT HR V +A +LK L LDY+DLYLMH+P G+
Sbjct: 56 WDSGI-KRENIWITSKLWNTHHRLEIVEEACRKTLKDLRLDYLDLYLMHYPFAFQNTGIG 114
Query: 507 ADYSHSD----------VDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERV 632
+ D V ++TW+ +E G+VK IG+SN+ QLER+
Sbjct: 115 GSLNPLDEKGNTIFDDGVSLIDTWKAMEKLVEKGLVKRIGVSNWTINQLERL 166
>UniRef50_A2QL02 Cluster: Putative frameshift; n=1; Aspergillus
niger|Rep: Putative frameshift - Aspergillus niger
Length = 357
Score = 105 bits (252), Expect = 1e-21
Identities = 62/181 (34%), Positives = 96/181 (53%), Gaps = 11/181 (6%)
Frame = +3
Query: 147 MNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGE 326
+N G +PA+G+GT+ + D Q + V + + G R DTA VY EQ++G
Sbjct: 40 LNTGAKIPALGVGTF---------QDPDSQ-EETVCQVLQRGMRLIDTARVYGVEQQVGR 89
Query: 327 AVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLN 506
+K + V RE+IF+ TKLW +V +A++DSL+ L Y+DL LMH+P
Sbjct: 90 GIK----KSGVPREEIFLGTKLWCNDFHPDDVERAVDDSLRDLYTPYVDLLLMHYPCTFK 145
Query: 507 ADYS-----------HSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIK 653
H + F++TWR LE + G V+ IG+SNF+K ++E +L+E +
Sbjct: 146 RGEDRFPRDAEGRMIHGETTFVDTWRALEKVVKTGKVRAIGVSNFSKGEIETLLRETSTV 205
Query: 654 P 656
P
Sbjct: 206 P 206
>UniRef50_Q5K8C5 Cluster: Aldo-keto reductase, putative; n=1;
Filobasidiella neoformans|Rep: Aldo-keto reductase,
putative - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 303
Score = 105 bits (251), Expect = 1e-21
Identities = 62/167 (37%), Positives = 88/167 (52%)
Frame = +3
Query: 141 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 320
LKM++G +P GLG Y + DK+ D V A++ GYRH DTA YE E
Sbjct: 33 LKMHDGNAIPQFGLGVY---------EMNDKETYDCVKWALEAGYRHVDTAEWYENEAPC 83
Query: 321 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 500
G+A+ ++ RE+IF+T+KL N + SLK+ G++Y DLYLMH IG
Sbjct: 84 GKAIADFLKATGTSREEIFLTSKLKNNSSYEQAFVD-LKGSLKRSGVEYFDLYLMHSAIG 142
Query: 501 LNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKE 641
V W+ L DAQ G+VK IG+SNF K+ ++ + +
Sbjct: 143 -------GPVIRKNVWKALCDAQSQGLVKSIGVSNFGKKHIQEFIDQ 182
>UniRef50_Q88TV9 Cluster: Oxidoreductase; n=4; Lactobacillus|Rep:
Oxidoreductase - Lactobacillus plantarum
Length = 288
Score = 104 bits (250), Expect = 2e-21
Identities = 60/159 (37%), Positives = 90/159 (56%)
Frame = +3
Query: 129 EVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYET 308
+ P++ +N+GR +PAIG GT+ D ++ V A+ +GYRH DTA Y
Sbjct: 3 KTPTITLNDGRAIPAIGFGTFQIPDDGSTYQA--------VKEALVIGYRHIDTAVAYFN 54
Query: 309 EQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMH 488
E E+G+A+K + + R+ I++T+KLW + ++AI+ SL KL LDYIDLYL+H
Sbjct: 55 EDEVGQAIK----DSGIPRDQIWVTSKLWLQDYGFDAASRAIDRSLTKLRLDYIDLYLIH 110
Query: 489 WPIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSN 605
P G D W+ +E AQ+ G +K IG+SN
Sbjct: 111 QPYG----------DVPGAWQAMEAAQKAGKLKSIGVSN 139
>UniRef50_A5VK30 Cluster: 2,5-didehydrogluconate reductase; n=2;
Lactobacillus reuteri|Rep: 2,5-didehydrogluconate
reductase - Lactobacillus reuteri F275
Length = 300
Score = 104 bits (250), Expect = 2e-21
Identities = 62/175 (35%), Positives = 96/175 (54%), Gaps = 1/175 (0%)
Frame = +3
Query: 135 PSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQ 314
P +K+NNG +P +GLG + K+ + + +V AI Y DTA Y E
Sbjct: 11 PKIKLNNGHLIPQLGLGVW---------KASLAETQQMVKEAIMNDYVLIDTAKQYGNEA 61
Query: 315 EIGEAVKMKVEEGVVKREDIFITTKLWN-TQHRRTEVAQAINDSLKKLGLDYIDLYLMHW 491
+G+ ++ + KR+ IF+TTK++N Q ++ QA+N+ LKKL +Y+DL L+HW
Sbjct: 62 AVGQGIQDGFKATGRKRDSIFLTTKIFNGDQGDYDKLRQAVNEQLKKLQTNYVDLLLLHW 121
Query: 492 PIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
P+ N Y+ E+WR LED + G K IG+ NFN +++ +L IKP
Sbjct: 122 PV--NDKYN-------ESWRALEDIYKDGQAKAIGVCNFNVERMTDLLDHAKIKP 167
>UniRef50_Q68ST9 Cluster: Reductase AKOR2; n=2; Pleurotus
djamor|Rep: Reductase AKOR2 - Pleurotus djamor
Length = 306
Score = 104 bits (250), Expect = 2e-21
Identities = 68/188 (36%), Positives = 102/188 (54%), Gaps = 14/188 (7%)
Frame = +3
Query: 135 PSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQ 314
P + +N G MPA+ LG + G + + + Q ++ + A+ GYRH DTA +Y TE+
Sbjct: 5 PPIVLNTGARMPALALGGWAG-----LTEEERTQAKEWFLTALKSGYRHIDTAQIYYTEK 59
Query: 315 EIGEAVKMKVEEGVVKREDIFITTKL-WNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHW 491
+G A++ E + RE++FITTKL WN H R VA++ SL+ LG +YIDLYL+H+
Sbjct: 60 SVGNAIR----ESGIPREELFITTKLPWN-HHSR--VAESFQKSLENLGTEYIDLYLVHF 112
Query: 492 P----------IGLNADYSHSDVD---FMETWRGLEDAQRMGIVKGIGLSNFNKQQLERV 632
P N D S V+ + W +E G VK IG+SN++ + LE +
Sbjct: 113 PQRVFYDETTDFPRNPDGSIKVVNSPTLNDVWADVETLLDTGKVKAIGVSNYSIKTLEEL 172
Query: 633 LKEGTIKP 656
LK + P
Sbjct: 173 LKTAKVVP 180
>UniRef50_A1UEC5 Cluster: 2,5-didehydrogluconate reductase; n=20;
Corynebacterineae|Rep: 2,5-didehydrogluconate reductase
- Mycobacterium sp. (strain KMS)
Length = 283
Score = 104 bits (249), Expect = 2e-21
Identities = 58/168 (34%), Positives = 91/168 (54%)
Frame = +3
Query: 132 VPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETE 311
+PS+ +N+G +P +GLG V + + + V A++ GYR DTA+VY E
Sbjct: 11 IPSVSLNDGHSIPVLGLG---------VGELSEAEAERSVAAALEAGYRLIDTAAVYGNE 61
Query: 312 QEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHW 491
+G AV + RE+I++TTKL A SL++LGLDY+DLYL+HW
Sbjct: 62 AAVGRAVNASG----IPREEIYVTTKLAVADQGFGTSQDAARASLERLGLDYVDLYLIHW 117
Query: 492 PIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL 635
P G + Y +++W GL A++ G+ + IG+ NFN + L ++
Sbjct: 118 PAGDHGKY-------IDSWGGLMKAKQDGVARSIGVCNFNAEHLSNII 158
>UniRef50_Q89JN4 Cluster: Oxidoreductase; n=8; Rhizobiales|Rep:
Oxidoreductase - Bradyrhizobium japonicum
Length = 272
Score = 103 bits (247), Expect = 4e-21
Identities = 57/161 (35%), Positives = 92/161 (57%)
Frame = +3
Query: 153 NGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAV 332
NG +PAIGLGT+ + + VV +A+ +GYRH DTA VY+ E+E+G+ V
Sbjct: 7 NGARIPAIGLGTW---------ELSGRPCARVVEQALRLGYRHIDTAQVYDNEREVGDGV 57
Query: 333 KMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNAD 512
+ V+R+D+F+TTK+W ++ +++ +SL +L L +DL L+HWP
Sbjct: 58 RASG----VRRDDVFLTTKVWTNHFAPNDLERSVKESLARLRLPSVDLLLLHWP------ 107
Query: 513 YSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL 635
+S V ET L A++MG+ + IG+SNF +E+ +
Sbjct: 108 --NSHVPLAETLGALSHARQMGLTRHIGVSNFTVALIEQAV 146
>UniRef50_Q8ET73 Cluster: 2,5-diketo-D-gluconate reductase; n=12;
Bacteria|Rep: 2,5-diketo-D-gluconate reductase -
Oceanobacillus iheyensis
Length = 280
Score = 103 bits (246), Expect = 5e-21
Identities = 60/171 (35%), Positives = 92/171 (53%)
Frame = +3
Query: 129 EVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYET 308
++P++ +++G +P +G GTY +GV + AID GYR DTA YE
Sbjct: 4 QIPNVTLHDGLTIPKVGFGTYRLNGNDGV---------QAINNAIDHGYRLIDTAYNYEN 54
Query: 309 EQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMH 488
E +GEAV+ RE + IT+KL H + I +SL + LDY DLYL+H
Sbjct: 55 EGTVGEAVR----RSSTPREQLLITSKLPGRYHHYDKAVTTIQESLYRANLDYYDLYLIH 110
Query: 489 WPIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKE 641
WP + D+ ++E W+ L +A+R G ++ IG+ NF + LER+ +E
Sbjct: 111 WPNPI------QDI-YVEAWQALIEAKRRGYIRSIGVCNFLPEHLERLKQE 154
>UniRef50_Q0CK00 Cluster: Predicted protein; n=1; Aspergillus
terreus NIH2624|Rep: Predicted protein - Aspergillus
terreus (strain NIH 2624)
Length = 292
Score = 103 bits (246), Expect = 5e-21
Identities = 58/177 (32%), Positives = 99/177 (55%)
Frame = +3
Query: 126 MEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYE 305
M+ P+L + +G +P +G GT + ++ + +L +V+ A++ G+ H D A Y
Sbjct: 1 MKWPALSLKDGNLVPILGFGTGTAWYKDDPNDPTNPELIEVLKAALEKGFHHIDAADSYG 60
Query: 306 TEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLM 485
TE+E+G A++ E + RE +FITTK+ +V A++ SL++L LDY+DLYL+
Sbjct: 61 TEREVGIAIR----ESGIPREQLFITTKVLEGW---KDVPGALDASLERLQLDYVDLYLL 113
Query: 486 HWPIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
H P + + D W+GLE + G + IG+SNF + LE +L+ ++ P
Sbjct: 114 HNPYVI-----PNLTDIQSAWKGLEAVKATGKARSIGVSNFQRNHLEAILETCSVVP 165
>UniRef50_A7CUW0 Cluster: 2,5-didehydrogluconate reductase; n=6;
Bacteria|Rep: 2,5-didehydrogluconate reductase -
Opitutaceae bacterium TAV2
Length = 334
Score = 102 bits (245), Expect = 7e-21
Identities = 55/176 (31%), Positives = 96/176 (54%), Gaps = 1/176 (0%)
Frame = +3
Query: 132 VPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETE 311
+P+L +++G +P +GLG + D V + A + GYR DTA +Y E
Sbjct: 59 IPTLPLSDGTSIPQLGLGVWQMPDDGAGVP---------IQAAFNAGYRAIDTAPIYGNE 109
Query: 312 QEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHW 491
+ +G A++ + R++++ITTK+WN+ +A+ +SL +L L+Y+DLYL+HW
Sbjct: 110 EGVGRAIRASG----LPRKELYITTKVWNSAQGYDSTLRAVRESLGRLQLEYVDLYLIHW 165
Query: 492 PIGLNADYSHSDVD-FMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
P+ +D +++TW+ L + G+ + IG+SNF L+R+ E I P
Sbjct: 166 PV--------PKIDRYVDTWKALAKIKADGLARSIGVSNFTPVYLQRLFDETGIVP 213
>UniRef50_UPI00015B4912 Cluster: PREDICTED: similar to aldo-keto
reductase; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to aldo-keto reductase - Nasonia vitripennis
Length = 353
Score = 102 bits (244), Expect = 9e-21
Identities = 66/185 (35%), Positives = 102/185 (55%), Gaps = 14/185 (7%)
Frame = +3
Query: 144 KMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIG 323
++++G + P +GLGT+ G +++ L V+ A++ G H DT+ VY+ E+ IG
Sbjct: 32 RLSSGHNFPIVGLGTH-GLNED--------VLETVLTGALEKGIGHIDTSFVYKNEETIG 82
Query: 324 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP--- 494
+ +K +G KREDIF+T+KL + V + I SL+KLGL Y+D+YL+H P
Sbjct: 83 KVLKDWFAKGG-KREDIFVTSKLPYYDNHPESVEKYIKLSLEKLGLQYLDMYLIHAPFAV 141
Query: 495 --------IGLNADYS---HSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKE 641
+ N D S + D + W+ +E + G K IGLSNFN+ Q+ +LKE
Sbjct: 142 HHKEDSYELATNEDGSVVLDTQTDPIAVWKEMEKQVKEGRTKSIGLSNFNETQITNILKE 201
Query: 642 GTIKP 656
IKP
Sbjct: 202 AKIKP 206
>UniRef50_Q02198 Cluster: Morphine 6-dehydrogenase; n=5;
Bacteria|Rep: Morphine 6-dehydrogenase - Pseudomonas
putida
Length = 296
Score = 102 bits (244), Expect = 9e-21
Identities = 56/174 (32%), Positives = 93/174 (53%)
Frame = +3
Query: 135 PSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQ 314
P + +NNG MPA+GLG + + ++ + AI GYR DTA Y E
Sbjct: 6 PLINLNNGVKMPALGLGVFA---------ASAEETASAIASAISSGYRLIDTARSYNNEA 56
Query: 315 EIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 494
++GE ++ V R ++F+TTKL+N + +A ++SL +LGLDY+DLYL+HWP
Sbjct: 57 QVGEGIR----NSGVDRAEMFVTTKLFNCDYGYERALRAFDESLGRLGLDYVDLYLLHWP 112
Query: 495 IGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
D++ + +++W+ E G + IG+ NF + QL+ ++ + P
Sbjct: 113 ---TKDWNAT----IQSWKAAEKILGDGRARAIGVCNFLEDQLDELIAASDVVP 159
>UniRef50_Q9A2X8 Cluster: Oxidoreductase, aldo/keto reductase
family; n=3; Caulobacter|Rep: Oxidoreductase, aldo/keto
reductase family - Caulobacter crescentus (Caulobacter
vibrioides)
Length = 279
Score = 101 bits (243), Expect = 1e-20
Identities = 61/169 (36%), Positives = 92/169 (54%), Gaps = 2/169 (1%)
Frame = +3
Query: 165 MPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKV 344
MPA+G GT+ +NG +V +A+++GYRH DTA +Y E+++G A++
Sbjct: 15 MPALGFGTWQL--ENGTAVP-------LVEKALEIGYRHIDTAQIYGNERDVGAAIR--- 62
Query: 345 EEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHS 524
VKR++IF+TTK+W Q ++ ++ SL+KLG+D +DL L+HWP
Sbjct: 63 -NSGVKRDEIFLTTKVWIDQFADGDLQRSAEKSLEKLGVDQVDLLLLHWP--------KP 113
Query: 525 DVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERV--LKEGTIKPDAI 665
+V ET + L + G + IGLSNF QLE L E I D +
Sbjct: 114 EVPLAETLKALNAVRAKGWTRAIGLSNFPSAQLEEAAKLSEAPIATDQV 162
>UniRef50_A0JX62 Cluster: 2,5-didehydrogluconate reductase; n=9;
Bacteria|Rep: 2,5-didehydrogluconate reductase -
Arthrobacter sp. (strain FB24)
Length = 291
Score = 101 bits (243), Expect = 1e-20
Identities = 61/187 (32%), Positives = 92/187 (49%), Gaps = 13/187 (6%)
Frame = +3
Query: 135 PSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQ 314
P L +NNG + +G G Y K +V A++ GYRHFDTA++Y E
Sbjct: 5 PRLSLNNGVLIDQLGFGLY---------KVPPADAAGLVTMALEAGYRHFDTAAMYGNET 55
Query: 315 EIGEAVKMKVE-----------EGV--VKREDIFITTKLWNTQHRRTEVAQAINDSLKKL 455
+G+A+ E + RED+F+TTK+WN H +A + S+ L
Sbjct: 56 GVGKAIGALAGFAGGGPAGGSGEAAPSLSREDLFVTTKVWNDDHGYDATMRAFDTSMSNL 115
Query: 456 GLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL 635
G++Y+DLYL+HWP F E++R +E R G ++ IG+SNF LE +L
Sbjct: 116 GMEYVDLYLIHWPCARRG-------LFTESYRAMETLYREGRIRAIGVSNFQPAHLEHLL 168
Query: 636 KEGTIKP 656
+ + P
Sbjct: 169 ETAEVVP 175
>UniRef50_A5ZYE6 Cluster: Putative uncharacterized protein; n=1;
Ruminococcus obeum ATCC 29174|Rep: Putative
uncharacterized protein - Ruminococcus obeum ATCC 29174
Length = 263
Score = 101 bits (242), Expect = 2e-20
Identities = 61/164 (37%), Positives = 84/164 (51%)
Frame = +3
Query: 165 MPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKV 344
MP +GLG Y D + D + A+ GYR DTAS Y+ E+ +G +
Sbjct: 1 MPLLGLGLYKTTDA--------VEAEDAIAAAVQNGYRLLDTASAYKNEEFVG----CGI 48
Query: 345 EEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHS 524
+ V R+D+FITTK+WN R +V A SL +LGLDYIDLYL+HWP+
Sbjct: 49 AKCGVPRKDLFITTKIWNNAQRLGDVEGAFQRSLDRLGLDYIDLYLIHWPV--------- 99
Query: 525 DVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
F+ TW+ +E G IG+SNF + LE + + I P
Sbjct: 100 PGCFLNTWKDMEKILESGRALSIGVSNFEIRHLEELRRVSGIVP 143
>UniRef50_A5PDA8 Cluster: Putative oxidoreductase protein; n=1;
Erythrobacter sp. SD-21|Rep: Putative oxidoreductase
protein - Erythrobacter sp. SD-21
Length = 272
Score = 101 bits (242), Expect = 2e-20
Identities = 56/176 (31%), Positives = 95/176 (53%)
Frame = +3
Query: 129 EVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYET 308
+ P+L +N+GR +P +G GT+ + +++ V AIDVGY DTA++Y
Sbjct: 3 DYPTLNLNDGRQIPQLGFGTW---------QMEEEDAPQAVSTAIDVGYWLIDTAAIYGN 53
Query: 309 EQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMH 488
E+ +G+ GV + DIF+ TK+WN +A L++LG +++D+ L+H
Sbjct: 54 EKGVGK--------GVGEWSDIFLQTKIWNDSQGYDRTLRAAEKCLERLGREHVDMLLIH 105
Query: 489 WPIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
WP D F++TW+ L + + G K IG+SNF ++ L+R++ E + P
Sbjct: 106 WPC------PEKD-QFVDTWKALIELRDAGKAKSIGVSNFREEDLKRIIDETGVTP 154
>UniRef50_A3UJS6 Cluster: Oxidoreductase; n=3;
Alphaproteobacteria|Rep: Oxidoreductase - Oceanicaulis
alexandrii HTCC2633
Length = 275
Score = 101 bits (241), Expect = 2e-20
Identities = 55/158 (34%), Positives = 85/158 (53%)
Frame = +3
Query: 153 NGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAV 332
NG D+P +G GT+ + +D+ V A+ GYRH DTA +Y E +G+
Sbjct: 8 NGADIPKLGFGTW---------QLEDEDAARGVATALKTGYRHIDTAQIYGNEAAVGDGW 58
Query: 333 KMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNAD 512
K + VKRED F+TTK+W + R ++ ++ +SL KL DY+DL L+HWP+
Sbjct: 59 K----QSGVKREDFFLTTKVWRDKFRDGDLQASVKESLDKLKTDYVDLLLLHWPV----- 109
Query: 513 YSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLE 626
+V ET + + + + G V+ IG+SNF L+
Sbjct: 110 ---PEVPIAETMKAMNEVKEAGQVRHIGVSNFTVDLLD 144
>UniRef50_Q76L37 Cluster: Conjugated polyketone reductase C1; n=3;
Saccharomycetales|Rep: Conjugated polyketone reductase
C1 - Candida parapsilosis (Yeast)
Length = 304
Score = 101 bits (241), Expect = 2e-20
Identities = 63/175 (36%), Positives = 96/175 (54%), Gaps = 7/175 (4%)
Frame = +3
Query: 144 KMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIG 323
K++NG +PA+ GT + + G DKQL + A+ G+RH D A +Y T +EIG
Sbjct: 9 KLSNGNKIPAVAFGTGTKYFKRGH-NDLDKQLIGTLELALRSGFRHIDGAEIYGTNKEIG 67
Query: 324 EAVKMKVEEGVVKREDIFITTKLWNTQH-------RRTEVAQAINDSLKKLGLDYIDLYL 482
A+K G+ R+D+FIT K + H + A+ L+ LGL+Y+DLYL
Sbjct: 68 IALK---NVGL-NRKDVFITDKYNSGNHTYDGKHSKHQNPYNALKADLEDLGLEYVDLYL 123
Query: 483 MHWPIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGT 647
+H+P ++ SH D +E WR LE A+ G+ + IG+SNF + L+ +L T
Sbjct: 124 IHFPY--ISEKSHG-FDLVEAWRYLERAKNEGLARNIGVSNFTIENLKSILDANT 175
>UniRef50_A0JRJ6 Cluster: Aldo/keto reductase; n=2;
Micrococcineae|Rep: Aldo/keto reductase - Arthrobacter
sp. (strain FB24)
Length = 281
Score = 100 bits (239), Expect = 4e-20
Identities = 56/175 (32%), Positives = 91/175 (52%)
Frame = +3
Query: 132 VPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETE 311
+P L +NNG +P +G G + + ++ + +V A++ GYRH DTA+ Y E
Sbjct: 9 IPQLTLNNGVKIPQLGFGVF---------QVPPEETQRIVEDALEAGYRHIDTAAAYRNE 59
Query: 312 QEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHW 491
+G A + + REDIFITTKL N + +A +S K LG++++DLYL+HW
Sbjct: 60 AGVGAA----ISASGIPREDIFITTKLRNGEQGNAH--EAFQNSRKALGVEFVDLYLIHW 113
Query: 492 PIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
P+ Y+ E W+ +E ++ IG+SNF + L+ +L + P
Sbjct: 114 PVPSQGLYT-------EAWKAMEKLYANSQIRAIGVSNFLGEHLDTLLPAADVVP 161
>UniRef50_UPI0000DB6EE9 Cluster: PREDICTED: similar to C35D10.6;
n=2; Endopterygota|Rep: PREDICTED: similar to C35D10.6 -
Apis mellifera
Length = 292
Score = 99 bits (238), Expect = 5e-20
Identities = 60/173 (34%), Positives = 99/173 (57%), Gaps = 4/173 (2%)
Frame = +3
Query: 132 VPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQL-RDVVMRAIDVGYRHFDTASVYET 308
V ++ +++G DMP IG GTY K + ++L VV +++VG+R DTA Y
Sbjct: 5 VRNVCLSSGYDMPLIGFGTY---------KIQGRELVYQVVDESLNVGFRSIDTAVGYRN 55
Query: 309 EQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTE-VAQAINDSLKKLGLDYIDLYLM 485
E++IG A+K + + ++R DIFITTKL + + + + Q + SLK YIDLYL+
Sbjct: 56 EEDIGYALKNLLPKYNLQRSDIFITTKLPPSVNGDPKGIEQCVQKSLKAFNTTYIDLYLI 115
Query: 486 HWPIGLNADYSHSDVDFM--ETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLK 638
HWP + ++ + +TW L D ++ G ++ IG+SNF + L+ +L+
Sbjct: 116 HWPGATRIPETSTNNPSLRAKTWNKLVDLKKQGFIRSIGVSNFTIKHLQELLQ 168
>UniRef50_Q28P63 Cluster: Aldo/keto reductase; n=4;
Rhodobacteraceae|Rep: Aldo/keto reductase - Jannaschia
sp. (strain CCS1)
Length = 276
Score = 99 bits (238), Expect = 5e-20
Identities = 51/169 (30%), Positives = 92/169 (54%)
Frame = +3
Query: 135 PSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQ 314
P +K ++G +P +G G + + + V AI++GYR D A +Y E
Sbjct: 5 PVIKFHDGAQIPQVGFGIW---------QVPQDIAGETVRSAIEIGYRMIDGAYLYMNEA 55
Query: 315 EIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 494
+GE ++ + R+++F+TTK+WN + + ++ SLK +G++ +DL L+HWP
Sbjct: 56 GLGEGLRASG----LPRDEVFVTTKVWNNEQGAAKARASVERSLKTIGVEQLDLVLIHWP 111
Query: 495 IGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKE 641
+ D+ ++ETW+ +D + G+++ IG SNFN LER++ E
Sbjct: 112 V------PSQDL-YLETWKAFQDMRDEGLMRSIGTSNFNADHLERIIAE 153
>UniRef50_A7RRF6 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 275
Score = 99 bits (238), Expect = 5e-20
Identities = 54/170 (31%), Positives = 91/170 (53%)
Frame = +3
Query: 147 MNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGE 326
+++G +P GLG Y +K + V+ A++ GYR DTA+ Y E+ +GE
Sbjct: 9 LSDGYKIPRFGLGLY---------DLDEKHTKQAVLWALENGYRMIDTAASYNNEKRVGE 59
Query: 327 AVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLN 506
A++ E V R ++++ TK+++T H + +A + SL LG+DY+DLYL+H+P+
Sbjct: 60 ALR----ESAVPRSEVYLVTKVYHTDHGYEKTMKAYDRSLSALGVDYVDLYLIHFPV--- 112
Query: 507 ADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
+ +W + + Q G+ + IG+SNFN LE + K I P
Sbjct: 113 ------PAGVVGSWEAMAELQGKGLTRSIGVSNFNIHHLEALQKHSVIPP 156
>UniRef50_Q5FT75 Cluster: Putative 2,5-diketo-D-gluconic acid
reductase; n=1; Gluconobacter oxydans|Rep: Putative
2,5-diketo-D-gluconic acid reductase - Gluconobacter
oxydans (Gluconobacter suboxydans)
Length = 279
Score = 99.5 bits (237), Expect = 6e-20
Identities = 55/172 (31%), Positives = 90/172 (52%)
Frame = +3
Query: 141 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 320
+ ++G MP IGLG + ++ + +VV A+ +GYR DTA +Y+ E+ +
Sbjct: 14 ISFHDGHTMPQIGLGVW---------ETPPDETAEVVKEAVKLGYRSVDTARLYKNEEGV 64
Query: 321 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 500
G+ G+ +IF+TTKLWN + +A +S + L +DLYL+HWP+
Sbjct: 65 GK--------GLEDHPEIFLTTKLWNDEQGYDSTLRAYEESARLLRRPVLDLYLIHWPMP 116
Query: 501 LNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
Y +ETW+ L + ++ G VK IG+SNF + LER++ + P
Sbjct: 117 AQGQY-------VETWKALVELKKSGRVKSIGVSNFESEHLERIMDATGVVP 161
>UniRef50_A3VRL4 Cluster: Putative uncharacterized protein; n=1;
Parvularcula bermudensis HTCC2503|Rep: Putative
uncharacterized protein - Parvularcula bermudensis
HTCC2503
Length = 278
Score = 99.5 bits (237), Expect = 6e-20
Identities = 53/148 (35%), Positives = 90/148 (60%), Gaps = 1/148 (0%)
Frame = +3
Query: 192 LGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKRED 371
LGF G + + + R AI+ GYRH D A++Y+ E+++GE +K + + R++
Sbjct: 14 LGF---GTWQLEGEDARTSTRTAIETGYRHIDGAAIYKNEKKVGEGIK----DSGIPRDE 66
Query: 372 IFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWR 551
+F+TTK+WN ++ ++A+++SL +LGLDY++L L+HWPI +D+ +
Sbjct: 67 LFVTTKIWNEDIQKGRHSEAVDESLDRLGLDYVNLILLHWPI--------NDMPIADQVG 118
Query: 552 GLEDAQRMGIVKGIGLSNFNKQQ-LERV 632
L + +R G K IG+SN+N+ Q LE V
Sbjct: 119 PLAEIKRSGRAKLIGISNYNQAQFLEAV 146
>UniRef50_Q17568 Cluster: Putative uncharacterized protein; n=1;
Caenorhabditis elegans|Rep: Putative uncharacterized
protein - Caenorhabditis elegans
Length = 287
Score = 99.1 bits (236), Expect = 8e-20
Identities = 57/175 (32%), Positives = 101/175 (57%), Gaps = 4/175 (2%)
Frame = +3
Query: 144 KMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIG 323
K+ NG+++P + LGTY ++K QL V A+ VGYR FDTA YE E+++G
Sbjct: 3 KLKNGQEIPKLALGTY---------EAKGDQLFAAVDEALKVGYRSFDTAKYYENEKDLG 53
Query: 324 EAVKMKVEEGVVKREDIFITTKL--WNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 497
A+K + + EDI++T+K+ +++++ + + +N+SL+ L Y+DL L+H+P
Sbjct: 54 LALKTLLPRHNICSEDIYLTSKVFPYSSKNAAELIRKDVNESLELLDRKYLDLVLVHYPR 113
Query: 498 GLNA-DYSHSDVDF-METWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
L+ D + ++ + +TW LE G ++ IG+SN+ +E + TI+P
Sbjct: 114 PLDTEDLNENNKMYRKDTWIALEKLHAEGKIRSIGVSNYEPHHIEEMRSYITIEP 168
>UniRef50_A6RMS0 Cluster: Putative uncharacterized protein; n=1;
Botryotinia fuckeliana B05.10|Rep: Putative
uncharacterized protein - Botryotinia fuckeliana B05.10
Length = 286
Score = 99.1 bits (236), Expect = 8e-20
Identities = 65/173 (37%), Positives = 94/173 (54%)
Frame = +3
Query: 138 SLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 317
S ++ NG +PAIGLGT+ G D N VK+ +V AI GYRH D A+ Y E+
Sbjct: 7 SFRLVNGSTLPAIGLGTFQGDDGNEKVKN-------IVKAAIQAGYRHIDGAAAYGNEEA 59
Query: 318 IGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 497
IG+A+K E G+ + E + W H +V +A++ SL+ LGL+Y+ + P
Sbjct: 60 IGDAIK---ESGISRDE----LAQPW---HEPKDVERALDLSLEALGLEYVPHAYLPGP- 108
Query: 498 GLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
N DY S + ETW+ +E G K IGLSNFN + +R+L+ I+P
Sbjct: 109 -NNVDYERSR-KYTETWQAMEKLVDSGKAKAIGLSNFNILKTKRILEIARIRP 159
>UniRef50_Q8G7K9 Cluster: Dehydrogenase or reductase protein; n=4;
Bifidobacterium|Rep: Dehydrogenase or reductase protein
- Bifidobacterium longum
Length = 289
Score = 98.7 bits (235), Expect = 1e-19
Identities = 57/170 (33%), Positives = 90/170 (52%)
Frame = +3
Query: 132 VPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETE 311
VP + + +G +P +GLG L D GVV VV A++ GYRH D A+ Y E
Sbjct: 11 VPDIALKDGHSIPQVGLGV-LRIDDEGVVP--------VVESALEAGYRHIDGAAGYNNE 61
Query: 312 QEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHW 491
+G A+ KRE +++TTKL ++Q +A ++SLK L LDY+D+Y++HW
Sbjct: 62 AGVGRALAASGYNKGAKRETLWVTTKLRDSQQGYDSALKAFDNSLKLLQLDYVDMYMIHW 121
Query: 492 PIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKE 641
P D+ +D TW+ + G+ + +G+ NF L+R+ +E
Sbjct: 122 PTPF--DWRSTD-----TWKAFVKLRDEGMARTLGVCNFMPADLKRLHEE 164
>UniRef50_Q4V008 Cluster: Oxidoreductase; n=4; Proteobacteria|Rep:
Oxidoreductase - Xanthomonas campestris pv. campestris
(strain 8004)
Length = 267
Score = 98.7 bits (235), Expect = 1e-19
Identities = 53/148 (35%), Positives = 83/148 (56%)
Frame = +3
Query: 165 MPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKV 344
+PA GLGT+ + KD+ + D V A+ +GYR DTA +Y+ E ++G+A+
Sbjct: 3 VPAFGLGTF---------RLKDQVVIDSVRNALALGYRAIDTAQIYDNEAQVGQAIA--- 50
Query: 345 EEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHS 524
+ V R+ +F+TTK+W + R + ++ +SL+KLG DY+DL L+HWP
Sbjct: 51 -DAGVPRDQLFVTTKIWVDRFSRDTLQPSLQESLRKLGTDYVDLTLIHWP------SPKD 103
Query: 525 DVDFMETWRGLEDAQRMGIVKGIGLSNF 608
V E L DA+ G+ + IG+SNF
Sbjct: 104 QVPMREYLEALADAKAQGLTRAIGVSNF 131
>UniRef50_Q5TNP1 Cluster: ENSANGP00000029046; n=2; Culicidae|Rep:
ENSANGP00000029046 - Anopheles gambiae str. PEST
Length = 331
Score = 98.7 bits (235), Expect = 1e-19
Identities = 61/181 (33%), Positives = 92/181 (50%), Gaps = 13/181 (7%)
Frame = +3
Query: 138 SLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 317
+ K+N G D+P G GTY Q + + D A++ GYRH DTA VY E+
Sbjct: 33 TFKLNTGFDIPLAGFGTYQIHGQELIYQVLDY--------ALEAGYRHIDTAVVYRNEEY 84
Query: 318 IGEAVKMKVEEGVVKREDIFITTKLWNTQHR-RTEVAQAINDSLKKLGLDYIDLYLMHWP 494
IG A+K + + +KREDIFIT+KL + + V Q + SL L DY+DLYL+HWP
Sbjct: 85 IGTALKTLLPKYNLKREDIFITSKLISQSGKDEAFVEQMVRKSLANLQTDYLDLYLIHWP 144
Query: 495 ------------IGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLK 638
G+ + + +W L +R G ++ IG+SN+ + L+ +L
Sbjct: 145 GVSGKCGRWKWLFGMQVTHPDNVKYRAASWNALSKLEREGCLRSIGVSNYTVKHLKEMLA 204
Query: 639 E 641
+
Sbjct: 205 D 205
>UniRef50_Q5UX52 Cluster: Oxidoreductase aldo/keto reductase family;
n=1; Haloarcula marismortui|Rep: Oxidoreductase
aldo/keto reductase family - Haloarcula marismortui
(Halobacterium marismortui)
Length = 274
Score = 98.7 bits (235), Expect = 1e-19
Identities = 57/158 (36%), Positives = 86/158 (54%)
Frame = +3
Query: 156 GRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVK 335
G +PA+GLGT+ + + R+ V A+ +GYRH DTA Y E+++G
Sbjct: 8 GTSVPALGLGTW---------QLTGQSCRETVETALGMGYRHIDTAQAYGNERQVG---- 54
Query: 336 MKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADY 515
+ ++ V RED+F+TTKL + V ++ +SL KLG DY+DL L+HWP N +
Sbjct: 55 LGMDAAAVDREDVFLTTKLDGSNRDERSVRRSTRESLNKLGTDYLDLLLIHWP---NTPW 111
Query: 516 SHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLER 629
S ET + D G+V+ IG+SNF+ L+R
Sbjct: 112 MAS---LSETLGAMNDVVEEGLVRHIGVSNFSPSLLDR 146
>UniRef50_Q6U5V3 Cluster: Putative uncharacterized protein; n=1;
Klebsiella pneumoniae|Rep: Putative uncharacterized
protein - Klebsiella pneumoniae
Length = 279
Score = 98.3 bits (234), Expect = 1e-19
Identities = 54/177 (30%), Positives = 97/177 (54%)
Frame = +3
Query: 126 MEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYE 305
M S+ +N+G MP G G +L + ++D + ++ +A+ G+RHFDTA Y
Sbjct: 1 MTTDSILLNDGYYMPRPGCGLWL-------IDNRD--VDSLIRQALKAGFRHFDTAQAYF 51
Query: 306 TEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLM 485
E +G A++ V RE +FIT+K+ + N++L++LG++Y++L+L+
Sbjct: 52 NEDGVGRALRYTE----VPREQLFITSKIRGRDMGYARTLVSFNETLERLGVEYLELFLI 107
Query: 486 HWPIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
HWPI Y +ETW + + G+++ IG+SNF Q +ER++++ + P
Sbjct: 108 HWPIPAKNLY-------VETWEASIELEASGLIRSIGVSNFTCQHIERLIEDTGVVP 157
>UniRef50_Q7QVQ9 Cluster: GLP_302_44328_45269; n=1; Giardia lamblia
ATCC 50803|Rep: GLP_302_44328_45269 - Giardia lamblia
ATCC 50803
Length = 313
Score = 98.3 bits (234), Expect = 1e-19
Identities = 60/170 (35%), Positives = 86/170 (50%), Gaps = 15/170 (8%)
Frame = +3
Query: 192 LGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVK--MKVEEGVVKR 365
LGF G ++ + ++ V A+ GYRH D A VY+ E+ IG A K +KR
Sbjct: 7 LGF---GTWQAPPEAVQTAVETALMTGYRHIDCAYVYQNEEAIGRAFGKIFKDASSGIKR 63
Query: 366 EDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL----NADYSHSD-- 527
ED++IT+KLWN HR V + ++ L +DY+DL+L+HWP+ D D
Sbjct: 64 EDVWITSKLWNYNHRPELVREQCKKTMSDLQVDYLDLFLVHWPLAFVRNDVGDLFPKDAE 123
Query: 528 -------VDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
V +TWR +E G+VK IG+SN+ L +L IKP
Sbjct: 124 GRAMLEKVPLADTWRAMEQLVEEGLVKHIGVSNYTVPLLADLLNYAKIKP 173
>UniRef50_A6VNW9 Cluster: Aldo/keto reductase precursor; n=1;
Actinobacillus succinogenes 130Z|Rep: Aldo/keto
reductase precursor - Actinobacillus succinogenes 130Z
Length = 315
Score = 97.9 bits (233), Expect = 2e-19
Identities = 59/176 (33%), Positives = 95/176 (53%)
Frame = +3
Query: 138 SLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 317
++K+NNG +MP IG+G + +Q V A+ GYR DTA +Y EQ
Sbjct: 44 TVKLNNGIEMPIIGIGVWT---------LTPEQTEKSVGEALKAGYRLIDTARMYRNEQA 94
Query: 318 IGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 497
+G AV+ + + RE+IFITTK++ + A AIN+ L+ L DYIDL L+H+P
Sbjct: 95 VGRAVR----DSGIPREEIFITTKIYGSGDYANAEA-AINERLRLLDTDYIDLLLLHYP- 148
Query: 498 GLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAI 665
D + + W+ +E + G ++ IGLSN++++ R+++ TI P +
Sbjct: 149 ---------DQNDTKAWKVMEQFVKAGKIRAIGLSNYHRKTFNRIMQAATITPAVV 195
>UniRef50_Q929C8 Cluster: Lin2349 protein; n=12; Listeria|Rep:
Lin2349 protein - Listeria innocua
Length = 294
Score = 97.5 bits (232), Expect = 3e-19
Identities = 56/164 (34%), Positives = 88/164 (53%)
Frame = +3
Query: 165 MPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKV 344
+P IGLG + +Q + + +K AI+VGYR FDTA+VY E +G+A+
Sbjct: 17 IPYIGLGVFQVTEQEFIAGAVEK--------AIEVGYRLFDTAAVYNNEAIVGQAIL--- 65
Query: 345 EEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHS 524
+ V RE++FI++K+WN E A +L+ L LDY+DLYL+HWP+
Sbjct: 66 -DSAVPREELFISSKVWNGDLGYDETLFAFERTLRNLKLDYLDLYLIHWPVA-------- 116
Query: 525 DVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
+ ++WR +E ++K IG++NF + L +L KP
Sbjct: 117 -GKYRDSWRAMERLHDEKLIKSIGVANFKQHHLSDLLVAANEKP 159
>UniRef50_Q7VHE1 Cluster: Putative uncharacterized protein; n=1;
Helicobacter hepaticus|Rep: Putative uncharacterized
protein - Helicobacter hepaticus
Length = 270
Score = 97.5 bits (232), Expect = 3e-19
Identities = 66/173 (38%), Positives = 93/173 (53%)
Frame = +3
Query: 138 SLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 317
+L +NNG MP +GLGTY G K+ K + + AI+VGYR FD+A +Y E E
Sbjct: 3 TLTLNNGVKMPILGLGTY---SLTG--KAGQKAMSE----AIEVGYRLFDSAQMYNNEAE 53
Query: 318 IGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 497
+G A+ V+ G +KRE+ FI TKL + ++I SLK LGLDYID L+H P
Sbjct: 54 LGAAINAAVKGG-IKREEFFIQTKLLESSSEDL-AKKSIEKSLKTLGLDYIDSLLIHMP- 110
Query: 498 GLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
YS S +R +E + GI++ IG+SNF + +K + P
Sbjct: 111 -----YSQSKA----MYRAMESFYKQGILRVIGISNFGAKAYSEFVKSCEVIP 154
>UniRef50_Q03U37 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=5; Lactobacillus|Rep: Aldo/keto
reductase of diketogulonate reductase family -
Lactobacillus brevis (strain ATCC 367 / JCM 1170)
Length = 282
Score = 97.5 bits (232), Expect = 3e-19
Identities = 60/161 (37%), Positives = 86/161 (53%)
Frame = +3
Query: 144 KMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIG 323
K+ +GR MP +G GTYL DQ + + A D GYR FDTA +Y E +G
Sbjct: 11 KLADGRQMPVMGFGTYLLNDQ--------PTMNTAIQTAWDAGYRMFDTAMLYRNEDILG 62
Query: 324 EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL 503
A++ + G+ RE +F+T+K+ + +A+ SLK+L DY+DL L+HWP+
Sbjct: 63 PAIQ---QLGL-PREGLFLTSKVAEIVQGYDQTMKAVEGSLKRLQTDYLDLLLIHWPV-- 116
Query: 504 NADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLE 626
H F +TWR LE + G VK IG+SN+ LE
Sbjct: 117 ---REH----FFDTWRALEQLKADGQVKSIGVSNYTIAHLE 150
>UniRef50_Q927P9 Cluster: Lin2739 protein; n=12; Bacteria|Rep:
Lin2739 protein - Listeria innocua
Length = 283
Score = 96.3 bits (229), Expect = 6e-19
Identities = 60/173 (34%), Positives = 85/173 (49%)
Frame = +3
Query: 138 SLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 317
++K+NNG ++P +G GTY D + V AI GYRH DTA Y E+
Sbjct: 3 TVKLNNGIEVPILGFGTYQITDAG--------EAEQAVKEAIAAGYRHIDTAQSYMNEEA 54
Query: 318 IGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 497
+G + GV R+++FITTK+W V + + SLK+LGLDYIDL L+H P
Sbjct: 55 VGRGI---AASGV-DRKELFITTKIWVENVSYKGVMSSFDRSLKRLGLDYIDLLLIHQPY 110
Query: 498 GLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
D W +E+ Q G +K IG+SNF ++ + I P
Sbjct: 111 N----------DVYGAWMAMEELQAQGKIKAIGVSNFGVDRVVDLAAFNDITP 153
>UniRef50_Q890A0 Cluster: Oxidoreductase; n=6; Lactobacillales|Rep:
Oxidoreductase - Lactobacillus plantarum
Length = 282
Score = 96.3 bits (229), Expect = 6e-19
Identities = 53/139 (38%), Positives = 77/139 (55%), Gaps = 3/139 (2%)
Frame = +3
Query: 249 VMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQ 428
V A+ GYRH DTA Y+ E +G+A++ + + RE IF+TTKL
Sbjct: 36 VRAALAAGYRHIDTALAYQNEASVGQAIR----DSGIPREQIFVTTKLPAETKSYQGALN 91
Query: 429 AINDSLKKLGLDYIDLYLMH--WPIG-LNADYSHSDVDFMETWRGLEDAQRMGIVKGIGL 599
+ SLK LGLDY+DLYL+H WP G + Y +++D W+ +E + G K IG+
Sbjct: 92 DFDRSLKNLGLDYVDLYLVHAPWPWGQVGRVYDEANLD---VWQAMEAIYQSGRAKAIGV 148
Query: 600 SNFNKQQLERVLKEGTIKP 656
SNF + L+ +L + TI P
Sbjct: 149 SNFAVRDLKNILNQATIPP 167
>UniRef50_Q54NR2 Cluster: Aldo-keto reductase; n=3; Dictyostelium
discoideum AX4|Rep: Aldo-keto reductase - Dictyostelium
discoideum AX4
Length = 305
Score = 96.3 bits (229), Expect = 6e-19
Identities = 57/171 (33%), Positives = 90/171 (52%), Gaps = 8/171 (4%)
Frame = +3
Query: 165 MPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKV 344
MP +G+GT+ K + +++ ++ GYR DTAS+Y E+ IG+ + V
Sbjct: 27 MPMLGIGTF-----------KLNDIENIIKVGLENGYRRIDTASMYNNEERIGKVLNEMV 75
Query: 345 --EEGV----VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP--IG 500
+G+ +KRED+FIT+K + +A SLKKL LDY+D YL+HWP G
Sbjct: 76 TKNDGLDGKKIKREDLFITSKCSFMEQGYENALKAFESSLKKLQLDYLDCYLIHWPGVKG 135
Query: 501 LNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIK 653
L+ S + + +TWR LE + V+ IG+SN+ L +L ++
Sbjct: 136 LDGSDSGNSIQRAQTWRALEKLYQDKKVRSIGVSNYTINHLTELLSSPNLQ 186
>UniRef50_P91997 Cluster: Putative uncharacterized protein; n=4;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 297
Score = 96.3 bits (229), Expect = 6e-19
Identities = 59/180 (32%), Positives = 98/180 (54%), Gaps = 5/180 (2%)
Frame = +3
Query: 138 SLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 317
S K+N+G ++P +G GTY K + + + A+ GYR FDTA Y E+E
Sbjct: 12 SQKLNSGYNIPFVGFGTY---------KVTGENVPPAIDAALTAGYRMFDTAKYYLNEKE 62
Query: 318 IGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQA-INDSLKKLGLDYIDLYLMHWP 494
+GEA+K+ + + + R D+F+T+K + E + + +SL+ L DYID+YL+H+P
Sbjct: 63 LGEALKILLPKHGLSRSDVFLTSKFFPESKNCREACRGFVEESLQSLQTDYIDMYLVHYP 122
Query: 495 IGLNADYSHSDVDFME----TWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDA 662
++D + DV+ E + LE+A+ G V+ IG+SN+ LE + + P A
Sbjct: 123 KPNDSD--NDDVNNAEYRKIAYEVLEEAKAAGKVRSIGVSNYEIVHLEELKTYAKVPPCA 180
>UniRef50_A3VHZ9 Cluster: Oxidoreductase; n=1; Rhodobacterales
bacterium HTCC2654|Rep: Oxidoreductase - Rhodobacterales
bacterium HTCC2654
Length = 278
Score = 95.9 bits (228), Expect = 8e-19
Identities = 58/172 (33%), Positives = 89/172 (51%)
Frame = +3
Query: 135 PSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQ 314
P++ + NG +MP +GLGT+ D + V AI+ GYR DTA Y+ E
Sbjct: 8 PTVTLANGVEMPQLGLGTW---------PMTDDEAAKAVATAIETGYRLIDTAENYKNET 58
Query: 315 EIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 494
+G+ ++ + V R+++F+TTK+ H +A SL++LGLDYIDL+L+HWP
Sbjct: 59 GVGQGIR----DAGVARDEVFLTTKMNKQWHSVDGARRACEASLERLGLDYIDLFLIHWP 114
Query: 495 IGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTI 650
N D ++E + GL G+V+ IG SNF L + G +
Sbjct: 115 ---NPDQG----TYVEAFEGLTRLLDAGLVRAIGTSNFLPHHLNDLFAAGFV 159
>UniRef50_A5BF24 Cluster: Putative uncharacterized protein; n=1;
Vitis vinifera|Rep: Putative uncharacterized protein -
Vitis vinifera (Grape)
Length = 212
Score = 95.5 bits (227), Expect = 1e-18
Identities = 54/147 (36%), Positives = 86/147 (58%), Gaps = 9/147 (6%)
Frame = +3
Query: 243 DVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVK-REDIFITTKLWNTQHRRTE 419
D ++ AI++GYRHFD + Y +E+ +GEA+K V+ G++K R+++FIT
Sbjct: 30 DSILTAIELGYRHFDCVAAYLSEKPLGEAIKKAVKLGLIKSRDELFITL----------- 78
Query: 420 VAQAINDSLKKLGLDYIDLYLMHWPIGLN-ADYS-------HSDVDFMETWRGLEDAQRM 575
QA+N L LDY+DLYL+HW + L +Y H +D W+ +ED Q++
Sbjct: 79 --QALN-----LQLDYLDLYLIHWSVSLKPGNYELPVNKDDHLPIDLGSVWKAMEDFQKL 131
Query: 576 GIVKGIGLSNFNKQQLERVLKEGTIKP 656
+ K IG+SNF+ +LE +L+ +I P
Sbjct: 132 SLTKAIGVSNFSCNKLEELLQTASILP 158
>UniRef50_A5DRJ6 Cluster: Putative uncharacterized protein; n=4;
Pichia guilliermondii|Rep: Putative uncharacterized
protein - Pichia guilliermondii (Yeast) (Candida
guilliermondii)
Length = 287
Score = 95.5 bits (227), Expect = 1e-18
Identities = 59/162 (36%), Positives = 88/162 (54%), Gaps = 2/162 (1%)
Frame = +3
Query: 153 NGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAV 332
NG +PA G+G YL Q +V +A+DVGYR DTA YE E+E GE +
Sbjct: 14 NGSRIPACGVGVYL---------LPASQTAGIVEKALDVGYRLIDTAQEYENERETGEGI 64
Query: 333 KMKV-EEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKL-GLDYIDLYLMHWPIGLN 506
K + ++ KRED+ TTK+ N +++ +SL K+ L+YIDL L+H P+
Sbjct: 65 KAWLGKDKNNKREDVLYTTKITNLNQGYDRTWRSLKESLNKVKHLEYIDLVLIHDPLS-- 122
Query: 507 ADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERV 632
+ETW+ L++A G+VK IG+SNF K ++ +
Sbjct: 123 -----DKKTRIETWKALQEAVDSGMVKSIGVSNFGKHHIQEL 159
>UniRef50_A0AWM8 Cluster: Aldo/keto reductase; n=4;
Actinomycetales|Rep: Aldo/keto reductase - Arthrobacter
sp. (strain FB24)
Length = 287
Score = 95.1 bits (226), Expect = 1e-18
Identities = 54/177 (30%), Positives = 90/177 (50%)
Frame = +3
Query: 129 EVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYET 308
++P LK+ +G +P +GLGT+ + + V A+ GYR DTA Y
Sbjct: 12 DIPRLKLPHGHTIPRLGLGTW---------PMLEDECETAVRFALQSGYRLVDTAFQYRN 62
Query: 309 EQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMH 488
E+ +G ++ V R ++FI++K H V +A ++SL+KLGLD++D+++ H
Sbjct: 63 EEAVGRGIRT----AGVPRSELFISSKFNKESHSIDGVQRAYDESLRKLGLDHLDMFMCH 118
Query: 489 WPIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPD 659
WP+ Y ++ W+GL G VK IG+SNF L+ ++ + PD
Sbjct: 119 WPVPALGKY-------VDAWKGLVKLLEEGRVKAIGVSNFKPAHLKDIIDATGVVPD 168
>UniRef50_Q572D2 Cluster: Aldo-keto reductase, putative; n=1;
Phytophthora infestans|Rep: Aldo-keto reductase,
putative - Phytophthora infestans (Potato late blight
fungus)
Length = 255
Score = 95.1 bits (226), Expect = 1e-18
Identities = 57/178 (32%), Positives = 94/178 (52%)
Frame = +3
Query: 123 TMEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVY 302
++ VP+ + +G +P IGLG Y + + ++ ++ +GYRH DTA +Y
Sbjct: 2 SVNVPTKILPSGARIPMIGLGVYQS--------EPGPETYNAILTSLKLGYRHIDTAEIY 53
Query: 303 ETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYL 482
E+++G AV+ + + RE+IF+TTKL+ T ++ A S +LG+ YI LYL
Sbjct: 54 GNEEDVGRAVR----DSGIPREEIFVTTKLFTTNWGYSKALAAGKASNDRLGIVYIYLYL 109
Query: 483 MHWPIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
+H P + +TWR +ED + ++ IG+SNFN+ L + K IKP
Sbjct: 110 LHAP--------GPPKERADTWRAVEDLREQETLRDIGVSNFNETLLATLRKTAHIKP 159
>UniRef50_A7BES9 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 282
Score = 94.7 bits (225), Expect = 2e-18
Identities = 61/172 (35%), Positives = 94/172 (54%)
Frame = +3
Query: 141 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 320
+ +NNG +P +GLGTYL ++ D Q V A+D Y DTA+VY E+ +
Sbjct: 4 ITLNNGITIPQVGLGTYL-------LEPDDAQ--SAVTYALDNDYTLIDTANVYVNERAV 54
Query: 321 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 500
G ++ + R++IF+ TKLW + R A A+ ++L++LG DYIDL ++H P G
Sbjct: 55 GRGMRASSKA----RDEIFLETKLWPSFFER---ASAVEETLERLGTDYIDLMILHQPAG 107
Query: 501 LNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
D + +R LE A + G ++ IGLSNF+ Q +R+L E + P
Sbjct: 108 ----------DTVAGYRILEKAHKEGKIRAIGLSNFDVAQTQRILDECEVVP 149
>UniRef50_Q15NA5 Cluster: Aldo/keto reductase; n=2;
Gammaproteobacteria|Rep: Aldo/keto reductase -
Pseudoalteromonas atlantica (strain T6c / BAA-1087)
Length = 273
Score = 94.3 bits (224), Expect = 2e-18
Identities = 55/157 (35%), Positives = 84/157 (53%)
Frame = +3
Query: 165 MPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKV 344
+P G GTY +K D +L V A+DVGYRH DTA YE E E+G+A+
Sbjct: 11 IPTPGFGTYR-------LKGDDAKL--AVENALDVGYRHIDTAQAYENEAEVGDAISASK 61
Query: 345 EEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHS 524
+ R ++F+TTK+W + ++ +SL +L DY+DL L+HWP + D +
Sbjct: 62 ----ISRGELFVTTKVWFDNLSADKFITSVQNSLTQLNTDYVDLLLVHWP---SPD---N 111
Query: 525 DVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL 635
V E + L+ + G+ + IG+SNF + QL+ L
Sbjct: 112 KVSMAEYLKELKACKERGLTRHIGVSNFTQSQLDEAL 148
>UniRef50_Q9P6D3 Cluster: Related to aldo-keto reductase YPR1; n=10;
Pezizomycotina|Rep: Related to aldo-keto reductase YPR1
- Neurospora crassa
Length = 322
Score = 94.3 bits (224), Expect = 2e-18
Identities = 53/160 (33%), Positives = 86/160 (53%), Gaps = 1/160 (0%)
Frame = +3
Query: 132 VPSLKMNNGRDMPAIGLGTYLGFDQNG-VVKSKDKQLRDVVMRAIDVGYRHFDTASVYET 308
+PSLK+++G ++P +G G ++G + + + + + A++ GY H D A VY
Sbjct: 24 IPSLKLSDGNEIPMLGYGLGTANYKSGDSADTISEPIVNATLTALNAGYAHLDGAEVYGN 83
Query: 309 EQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMH 488
E E+G A+ + + R ++ITTK V Q+ N SL+KLGLDY+DLYL+H
Sbjct: 84 EVELGRAIA----QSKLPRSSLYITTK--TIVRAGDTVTQSFNRSLEKLGLDYVDLYLLH 137
Query: 489 WPIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNF 608
P ++ + WR +E + G+ K IG+SNF
Sbjct: 138 SPF-----FAKNPEQLQAAWREMEKIKDSGMAKSIGVSNF 172
>UniRef50_Q11BF8 Cluster: Aldo/keto reductase; n=12; Bacteria|Rep:
Aldo/keto reductase - Mesorhizobium sp. (strain BNC1)
Length = 308
Score = 93.9 bits (223), Expect = 3e-18
Identities = 57/168 (33%), Positives = 89/168 (52%)
Frame = +3
Query: 153 NGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAV 332
+G +MP IGLG + ++ + V A+ +GYRH DTA+ Y E+E+GE +
Sbjct: 25 SGVEMPMIGLGVF---------QTPPDETTAAVEEALRLGYRHIDTAAAYGNEREVGEGI 75
Query: 333 KMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNAD 512
+ + R+++FI TK+W + + E A + S KLG+D IDL L+H P+ D
Sbjct: 76 R----RAGIARDEVFIETKIWISDYGYDETLHAFDKSAGKLGVDQIDLLLLHQPLPSAFD 131
Query: 513 YSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
+ + +R LE G V+ IG+SNF + L R+L E +I P
Sbjct: 132 RT------LGAYRALEKLLADGKVRAIGVSNFMPEHLTRLLTETSIVP 173
>UniRef50_UPI0000D56CE5 Cluster: PREDICTED: similar to CG6084-PA,
isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG6084-PA, isoform A - Tribolium castaneum
Length = 493
Score = 93.5 bits (222), Expect = 4e-18
Identities = 58/176 (32%), Positives = 94/176 (53%)
Frame = +3
Query: 129 EVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYET 308
++P K+NNG ++P GL F + V++ V + YR D S++E
Sbjct: 7 DIPIAKLNNGIEIPVFGLAAPQDFFE---VEN--------VQLVVSSNYRLMD-CSIFEN 54
Query: 309 EQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMH 488
E+ G A++ +E G ++R+D+F+ +K T V A+ D+LKKL + Y+DLYL+
Sbjct: 55 EKRFGVALQQLIEGGKIRRKDLFLMSKFCCTNTTNL-VKAALLDTLKKLQVAYLDLYLIE 113
Query: 489 WPIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
P D + +ETW +E + + IGLSNFN +Q+ER+L+ TI+P
Sbjct: 114 RPPACK------DHNLIETWEAMEGLYSEKLTRAIGLSNFNSKQIERILENCTIRP 163
Score = 74.9 bits (176), Expect = 2e-12
Identities = 38/86 (44%), Positives = 51/86 (59%), Gaps = 12/86 (13%)
Frame = +3
Query: 435 NDSLKKLGLDYIDLYLMHWPIGLNADYS-H-----------SDVDFMETWRGLEDAQRMG 578
++SLK L LDY+D+YLMHWP L S H SDVDF++TW+ +E
Sbjct: 270 SESLKNLQLDYLDVYLMHWPHALKEGPSLHPIDPKTGLFIPSDVDFVDTWKAMEKMHEKD 329
Query: 579 IVKGIGLSNFNKQQLERVLKEGTIKP 656
+ K IG+SNFN Q++R+LK I P
Sbjct: 330 LTKSIGISNFNSNQIDRLLKSAKIAP 355
>UniRef50_Q9HM42 Cluster: Alcohol dehydrogenase related protein;
n=1; Thermoplasma acidophilum|Rep: Alcohol dehydrogenase
related protein - Thermoplasma acidophilum
Length = 284
Score = 93.5 bits (222), Expect = 4e-18
Identities = 55/160 (34%), Positives = 87/160 (54%)
Frame = +3
Query: 156 GRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVK 335
GR + IG+GT+ + S+ + +R + A+D G DTA +Y TE +GEA+K
Sbjct: 13 GRKVSVIGVGTW------SLEGSRSENVRSI-RYALDHGVNFIDTAEMYGTEDIVGEAIK 65
Query: 336 MKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADY 515
+RED+FI TK+W T +V ++ +SLKKLG DY+DLY +HWP
Sbjct: 66 G------YRREDLFIATKVWPTHFAYHDVLKSCEESLKKLGTDYVDLYQLHWP------- 112
Query: 516 SHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL 635
+ V ET +E G ++ IG+SNF+ ++++ +
Sbjct: 113 -NPSVSIKETMSAMEKLVDEGRIRYIGISNFSVKEMKEAM 151
>UniRef50_Q8Y463 Cluster: Lmo2592 protein; n=40; Bacteria|Rep:
Lmo2592 protein - Listeria monocytogenes
Length = 283
Score = 93.1 bits (221), Expect = 5e-18
Identities = 56/162 (34%), Positives = 83/162 (51%)
Frame = +3
Query: 138 SLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 317
++K+NNG ++P +G GTY D + V AI GYRH DTA Y E+
Sbjct: 3 TVKLNNGVEVPILGFGTYQITDA--------AEAEHAVKDAIKAGYRHIDTAQSYMNEEA 54
Query: 318 IGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 497
+G + GV R+++FITTK+W V + + SLK+LGLDY+DL L+H P
Sbjct: 55 VGRGI---AASGV-DRKELFITTKIWVENVSYKGVMSSFDRSLKRLGLDYVDLLLIHQPF 110
Query: 498 GLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQL 623
D W +E+ Q G ++ IG+SNF+ ++
Sbjct: 111 N----------DVYGAWIAMEELQASGKIRAIGVSNFSPDRV 142
>UniRef50_A6PR52 Cluster: Aldo/keto reductase; n=1; Victivallis
vadensis ATCC BAA-548|Rep: Aldo/keto reductase -
Victivallis vadensis ATCC BAA-548
Length = 287
Score = 93.1 bits (221), Expect = 5e-18
Identities = 60/171 (35%), Positives = 94/171 (54%), Gaps = 4/171 (2%)
Frame = +3
Query: 129 EVPSLKMNNGRDMPAIGLGTY-LGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVY- 302
+VP + NG +P +G GT+ +G + D + + R I G H DTA +Y
Sbjct: 3 DVPWKSLKNGFAIPVLGQGTWRMGGVDTPDTANDDADIA-AIRRGIATGLCHIDTAEMYA 61
Query: 303 --ETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDL 476
E+ +G A+K +G+ +R D F+T K+W T R +V +A SLK+LG DYIDL
Sbjct: 62 GGHAEELVGIAMK---GQGI-RRADYFLTDKVWKTHLRYDDVLRAAEASLKRLGTDYIDL 117
Query: 477 YLMHWPIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLER 629
YL+H + DV ET R + +R G+++ IG+SNF++++L+R
Sbjct: 118 YLIH--------QVNPDVPEEETIRAMNRLKREGVIRHIGVSNFSEERLKR 160
>UniRef50_A0L1A2 Cluster: Aldo/keto reductase; n=8;
Gammaproteobacteria|Rep: Aldo/keto reductase -
Shewanella sp. (strain ANA-3)
Length = 280
Score = 92.7 bits (220), Expect = 7e-18
Identities = 54/150 (36%), Positives = 82/150 (54%), Gaps = 3/150 (2%)
Frame = +3
Query: 210 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 389
G + KD D V+ A++ G RH DTA +Y EQ +G+A+ + RE++FITTK
Sbjct: 23 GTFRLKDNAAFDAVLMALEEGSRHIDTAQIYGNEQAVGDAINTSG----IPREELFITTK 78
Query: 390 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQ 569
+W + ++ DSL L Y+DL L+HWP LN+D S V+++ + + D
Sbjct: 79 VWTENLTKERFETSVIDSLTALQTKYLDLLLIHWP--LNSD-EPSMVEYLSELKAVLD-- 133
Query: 570 RMGIVKGIGLSNFNKQQLER---VLKEGTI 650
G+ + IG+SNF QL + +L EG I
Sbjct: 134 -KGLTRRIGVSNFTNAQLAQAIAILGEGVI 162
>UniRef50_A6WDZ5 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:
Aldo/keto reductase - Kineococcus radiotolerans SRS30216
Length = 343
Score = 92.3 bits (219), Expect = 1e-17
Identities = 56/188 (29%), Positives = 94/188 (50%), Gaps = 13/188 (6%)
Frame = +3
Query: 132 VPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETE 311
VP ++ G +PAIG+GT+ G + ++ V A+ GYR D A+VY E
Sbjct: 13 VPRRELRGGATVPAIGIGTF------GSDRYSPAEVAAAVAGAVAAGYRLVDCAAVYGNE 66
Query: 312 QEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHW 491
++GEA+ V GV R+++F+ +K+WN H + +++ SL+ L LD++D +HW
Sbjct: 67 AQVGEALAGAVAGGV-DRDELFVVSKVWNDAHAPADAVASVHRSLRDLRLDHLDAVFVHW 125
Query: 492 PIGLNADYSHSDVD-------------FMETWRGLEDAQRMGIVKGIGLSNFNKQQLERV 632
P N +D D ++ W LE G+V+ +G SN +L+ +
Sbjct: 126 PFP-NHHPPMADTDARDPRARPYDHDAYLALWGALEGLVDSGLVRHLGTSNTTVAKLDLL 184
Query: 633 LKEGTIKP 656
L++ I P
Sbjct: 185 LRDARIPP 192
>UniRef50_Q7R2T6 Cluster: GLP_291_56367_57278; n=1; Giardia lamblia
ATCC 50803|Rep: GLP_291_56367_57278 - Giardia lamblia
ATCC 50803
Length = 303
Score = 92.3 bits (219), Expect = 1e-17
Identities = 60/178 (33%), Positives = 88/178 (49%), Gaps = 15/178 (8%)
Frame = +3
Query: 168 PAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVE 347
P +G GTYL D + + A+ +GYRHFD A Y E+ IGE K
Sbjct: 6 PCVGFGTYLVEDP------------EAIRSAVKLGYRHFDCAYRYGNERMIGEVFKEIFN 53
Query: 348 EGV--VKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGL----NA 509
+ VKRED++I +KLW H +VA I+++L+ L L+Y+D++LMHWP+ + +
Sbjct: 54 DDSYGVKREDLWIVSKLWPNFHEPEKVAYQISETLRDLQLEYLDVFLMHWPLAIKHLADR 113
Query: 510 DYSHSD---------VDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
DY+ SD +TW +E + IG+SN L +L IKP
Sbjct: 114 DYASSDGKGGTLLGTTPIRKTWEAMEACVDKKQTRFIGVSNMGTAMLVDLLSYCRIKP 171
>UniRef50_Q6WGK4 Cluster: Aldose reductase; n=1; Pristionchus
pacificus|Rep: Aldose reductase - Pristionchus pacificus
Length = 293
Score = 92.3 bits (219), Expect = 1e-17
Identities = 60/166 (36%), Positives = 88/166 (53%), Gaps = 2/166 (1%)
Frame = +3
Query: 165 MPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKV 344
MP IG+GTY V+S+ L D + A +GYR DTA +Y E +G + +
Sbjct: 16 MPMIGVGTYQ-------VQSQSV-LTDTIDEAFRLGYRFIDTAQIYRNEAILGRILPDLL 67
Query: 345 EEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHS 524
E+ +KREDIFIT+K+ + + ++++ SL L YIDL L+HWP +H
Sbjct: 68 EKHSLKREDIFITSKVSPINQGKGKTSKSVLKSLTDLQTPYIDLVLIHWPGTSRLKSNHK 127
Query: 525 D-VDF-METWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
D F ET+ LE G ++ IG+SN+ + LE +L E I P
Sbjct: 128 DNAKFRAETYVELETLMDEGKIRSIGVSNYEIKHLETLLAECRILP 173
>UniRef50_Q18483 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 287
Score = 92.3 bits (219), Expect = 1e-17
Identities = 53/166 (31%), Positives = 89/166 (53%), Gaps = 1/166 (0%)
Frame = +3
Query: 162 DMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMK 341
+MP IG+GT+ K++ LR V+ GYR DTA VY E +IG ++
Sbjct: 10 NMPLIGIGTWQ--------VQKEEILRQVIDAGFKEGYRFIDTAQVYNNEAKIGRILEKL 61
Query: 342 VEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP-IGLNADYS 518
+ +KREDI+IT+KL + + ++I +SL L ++Y+DL L+HWP L ++
Sbjct: 62 LPANGLKREDIWITSKLAPSNAGVKKARESIEESLSNLKVEYLDLLLIHWPGSSLKSENP 121
Query: 519 HSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
+ +E+W + + G ++ +G+SNF LE + K+ + P
Sbjct: 122 ANKKLRVESWNVMCEMMAEGKLRSVGVSNFEICHLEELKKDSNVVP 167
>UniRef50_O14088 Cluster: Xylose and arabinose reductase; n=1;
Schizosaccharomyces pombe|Rep: Xylose and arabinose
reductase - Schizosaccharomyces pombe (Fission yeast)
Length = 275
Score = 92.3 bits (219), Expect = 1e-17
Identities = 58/165 (35%), Positives = 86/165 (52%)
Frame = +3
Query: 141 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 320
+K+NNG P G+Y+ V ++K D V A+ GYRH D+A +Y E +
Sbjct: 6 VKLNNGLKCPQFAYGSYM------VNRTK---CFDSVYAALQCGYRHIDSAQMYHNEADC 56
Query: 321 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 500
G A+ +EE KREDI+ T+KL N +I+ S+K GL YIDL+L+H P G
Sbjct: 57 GRAILKFMEETGTKREDIWFTSKL-NDLSGYKSTLSSIDASVKACGLGYIDLFLLHSPYG 115
Query: 501 LNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL 635
D +E+W+ LE G ++ IG+SNF ++ +L
Sbjct: 116 ----------DRIESWKALEKGVEEGKLRAIGVSNFGPHHIQELL 150
>UniRef50_Q4FY75 Cluster: Aldo-keto reductase-like protein; n=5;
Trypanosomatidae|Rep: Aldo-keto reductase-like protein -
Leishmania major strain Friedlin
Length = 372
Score = 91.9 bits (218), Expect = 1e-17
Identities = 57/184 (30%), Positives = 85/184 (46%), Gaps = 18/184 (9%)
Frame = +3
Query: 141 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 320
+ M + +P +G GTY + + D V A+ GYRH D A Y E +
Sbjct: 22 IAMRDSHTIPQLGFGTY---------RLPVSEATDAVAFALSCGYRHVDCAKAYGNEAAV 72
Query: 321 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIG 500
GEA+ + +RED+F+T+KLW T V A +L L LDY+DLYL+HWP+
Sbjct: 73 GEALAQALRTRCTRREDLFVTSKLWPTDQHPDHVEAACRATLAALQLDYLDLYLIHWPVC 132
Query: 501 L------NADYS----HSD--------VDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLE 626
+ +D H D V ++TW + G+VK IGL+N +
Sbjct: 133 MRHTPHWTSDEDRYPRHRDGTPAIDTSVTLLDTWTAMNRLVDRGLVKSIGLANCTTAHVN 192
Query: 627 RVLK 638
++K
Sbjct: 193 DLVK 196
>UniRef50_A2UAH0 Cluster: Aldo/keto reductase; n=1; Bacillus
coagulans 36D1|Rep: Aldo/keto reductase - Bacillus
coagulans 36D1
Length = 273
Score = 91.5 bits (217), Expect = 2e-17
Identities = 57/173 (32%), Positives = 91/173 (52%), Gaps = 3/173 (1%)
Frame = +3
Query: 147 MNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGE 326
+ NG +P IGLGT+ NG + V A+ GYRH DTA Y E+ +G+
Sbjct: 10 LENGVAIPKIGLGTWQV--PNG------ETTYHAVSFALKNGYRHIDTAYAYHNEESVGK 61
Query: 327 AVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMH--WPIG 500
AV+ + + R DIF+T+KL + + ++++ GL+ +DLYL+H WP
Sbjct: 62 AVR----DSGIDRRDIFVTSKLPAEIKSYDKALKTFDETMGNFGLEQLDLYLIHAPWPWS 117
Query: 501 -LNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
ADY+ ++ E W+ +E+ G + IG+SNF+ L+ V++ IKP
Sbjct: 118 EKGADYTKENI---EVWKAMEEIYESGRCRAIGVSNFSVSDLKAVMENAKIKP 167
>UniRef50_Q21274 Cluster: Putative uncharacterized protein; n=1;
Caenorhabditis elegans|Rep: Putative uncharacterized
protein - Caenorhabditis elegans
Length = 301
Score = 91.5 bits (217), Expect = 2e-17
Identities = 60/180 (33%), Positives = 98/180 (54%), Gaps = 7/180 (3%)
Frame = +3
Query: 138 SLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDV-VMRAIDVGYRHFDTASVYETEQ 314
+ K ++G +MP IGLG + + + +Q DV + A+ GYR FDTA++Y+ E
Sbjct: 11 AFKFSDGYEMPKIGLG---------ISRIETQQDLDVSIEAALKSGYRQFDTANLYKNET 61
Query: 315 EIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRT--EVAQAINDSLKKLGLDYIDLYLMH 488
+G ++K + + + RED+FITTK+ T + T E + + +SL L DY+DL L+H
Sbjct: 62 FLGNSLKKYLPQFGLTREDVFITTKV-RTLNENTVEETEKQLANSLATLQTDYVDLLLIH 120
Query: 489 WP----IGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
+P G + DY + W+ LE A+ G V+ IG+SN+ L + + I+P
Sbjct: 121 YPRDRDTGNDDDYEINKSRRKIVWQTLEKAKESGRVRSIGVSNYEVYHLVEMFEYAKIRP 180
>UniRef50_Q8ZH36 Cluster: 2,5-diketo-D-gluconic acid reductase B;
n=91; Proteobacteria|Rep: 2,5-diketo-D-gluconic acid
reductase B - Yersinia pestis
Length = 267
Score = 91.5 bits (217), Expect = 2e-17
Identities = 45/142 (31%), Positives = 83/142 (58%)
Frame = +3
Query: 210 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 389
G + +D+ + D V +A+ +GYR DTA +YE E +G+A+ +E + R+++FITTK
Sbjct: 9 GTFRLQDQIVIDSVSQALTLGYRAIDTAQIYENEAPVGQAI----QESGINRDELFITTK 64
Query: 390 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQ 569
+W + ++ ++ +S++KL DY+DL L+HWP + +V E L A+
Sbjct: 65 IWIANLSKDKLIPSLRESIQKLKTDYVDLTLIHWP------SPNDEVSVAEFMSELLKAK 118
Query: 570 RMGIVKGIGLSNFNKQQLERVL 635
+G+ + IG+SNF +++ +
Sbjct: 119 GLGLTRQIGISNFTIDLMKQAI 140
>UniRef50_Q0SFM4 Cluster: Probable 2,5-didehydrogluconate reductase;
n=1; Rhodococcus sp. RHA1|Rep: Probable
2,5-didehydrogluconate reductase - Rhodococcus sp.
(strain RHA1)
Length = 265
Score = 91.1 bits (216), Expect = 2e-17
Identities = 58/160 (36%), Positives = 88/160 (55%)
Frame = +3
Query: 162 DMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMK 341
D+P +GLGT+ G ++ V+ I+ GYR DTA++Y+ E +G A+
Sbjct: 3 DIPPLGLGTW---PLTGPDATR------AVLSGIEAGYRLIDTATIYDNEDAVGVALA-- 51
Query: 342 VEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSH 521
E V RE++F+TTKL + H ++ A+ SLK LGLD +DL+L+HWP+ + Y
Sbjct: 52 --ECGVPREELFVTTKLRGSDHVSGDIRGAVERSLKNLGLDRLDLFLIHWPLPRHNRY-- 107
Query: 522 SDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKE 641
V E DA G+V+ +G+SNF + L RV+ E
Sbjct: 108 --VAAFEAMLACRDA---GLVRHVGVSNFLETHLRRVVAE 142
>UniRef50_Q76L36 Cluster: Conjugated polyketone reductase C2; n=1;
Candida parapsilosis|Rep: Conjugated polyketone
reductase C2 - Candida parapsilosis (Yeast)
Length = 307
Score = 91.1 bits (216), Expect = 2e-17
Identities = 53/169 (31%), Positives = 95/169 (56%), Gaps = 4/169 (2%)
Frame = +3
Query: 138 SLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 317
+ + +G+++ +I LGT + Q + +L D ++ + +G+RH DTA Y T++E
Sbjct: 10 TFRTKSGKEI-SIALGTGTKWKQAQTINDVSTELVDNILLGLKLGFRHIDTAEAYNTQKE 68
Query: 318 IGEAVKMKVEEGVVKREDIFITTKL---WNT-QHRRTEVAQAINDSLKKLGLDYIDLYLM 485
+GEA+K V REDI++TTK W + + + +I+ +L +LG+DY+DL+L+
Sbjct: 69 VGEALK----RTDVPREDIWVTTKYSPGWGSIKAYSKSPSDSIDKALAQLGVDYVDLFLI 124
Query: 486 HWPIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERV 632
H P + +H + W L +A++ G V+ IG+SN LE++
Sbjct: 125 HSPF-FTTEQTHG-YTLEQAWEALVEAKKAGKVREIGISNAAIPHLEKL 171
>UniRef50_A7TLC4 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 313
Score = 90.6 bits (215), Expect = 3e-17
Identities = 61/175 (34%), Positives = 96/175 (54%), Gaps = 5/175 (2%)
Frame = +3
Query: 147 MNNGRDMPAI---GLGTYLGFDQNGVVKSKDKQLRDVVMRAIDV-GYRHFDTASVYETEQ 314
+NNG +P+I G GT F + G + +L + + A+ + G H D A Y T
Sbjct: 10 LNNGNQIPSISIIGTGTRW-FKRPGSEHTFSDELVEQIKYALSLPGIIHIDAAECYGTYP 68
Query: 315 EIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRT-EVAQAINDSLKKLGLDYIDLYLMHW 491
E+ +A+K E R +IFIT K ++TQ + T + + +N LK LGLDY+DLYL+H
Sbjct: 69 ELAKALK----ESSKPRSEIFITDK-YSTQTKFTNDPIEGLNTGLKTLGLDYVDLYLIHS 123
Query: 492 PIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
P + ++ S + + W+ +E + G K IG+SNF+ + +E +LK IKP
Sbjct: 124 PF-FDPEFKGS-LTLEKVWKDMETLYKEGKAKSIGVSNFSVKNIEEILKIAGIKP 176
>UniRef50_Q3E9M9 Cluster: Uncharacterized protein At5g01670.2; n=7;
Magnoliophyta|Rep: Uncharacterized protein At5g01670.2 -
Arabidopsis thaliana (Mouse-ear cress)
Length = 349
Score = 90.2 bits (214), Expect = 4e-17
Identities = 63/200 (31%), Positives = 100/200 (50%), Gaps = 34/200 (17%)
Frame = +3
Query: 138 SLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 317
S ++ +G +PA+GLGT+ +S + VV ++ GYRH DTA Y ++E
Sbjct: 15 SFRLLSGHKIPAVGLGTW---------RSGSQAAHAVVTAIVEGGYRHIDTAWEYGDQRE 65
Query: 318 IGEAVKMKVEEGVVKREDIFITTKLWNT----------------------QHRRTE---- 419
+G+ +K + G ++R D+F+T+KLW T R TE
Sbjct: 66 VGQGIKRAMHAG-LERRDLFVTSKLWYTLILRKMINLSSPLMNVLVGTCLNKRCTELSPE 124
Query: 420 -VAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHS-------DVDFMETWRGLEDAQRM 575
V A+ ++LK+L L+Y+DLYL+HWPI L S D D WR +E+ +
Sbjct: 125 RVRPALQNTLKELQLEYLDLYLIHWPIRLREGASKPPKAGDVLDFDMEGVWREMENLSKD 184
Query: 576 GIVKGIGLSNFNKQQLERVL 635
+V+ IG+ NF +L ++L
Sbjct: 185 SLVRNIGVCNFTVTKLNKLL 204
>UniRef50_Q8EVS8 Cluster: Oxidoreductase; n=1; Mycoplasma
penetrans|Rep: Oxidoreductase - Mycoplasma penetrans
Length = 289
Score = 89.8 bits (213), Expect = 5e-17
Identities = 57/178 (32%), Positives = 93/178 (52%)
Frame = +3
Query: 123 TMEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVY 302
T V + +NNG +P+IG G + + ++ D V +AI +GYR DTA Y
Sbjct: 3 TSNVKLITLNNGNKIPSIGFGVF---------QIPKEETADCVKKAISIGYRLIDTAQAY 53
Query: 303 ETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYL 482
E+E G +K+ VKRE+IF+TTK+W + + R +++ +SLK+L Y+DL L
Sbjct: 54 HNEKETGLGIKL----SGVKREEIFLTTKVWVSNYER--CYESVIESLKRLDTSYLDLIL 107
Query: 483 MHWPIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
+H P G ++ + ++ LE + V+ IG+SNF ++ + IKP
Sbjct: 108 LHQPFG----------NYYKAYQDLERLYKENKVRNIGVSNFWDNRIIDLCFFNQIKP 155
>UniRef50_Q2BBN7 Cluster: YvgN; n=1; Bacillus sp. NRRL B-14911|Rep:
YvgN - Bacillus sp. NRRL B-14911
Length = 268
Score = 89.8 bits (213), Expect = 5e-17
Identities = 56/176 (31%), Positives = 89/176 (50%), Gaps = 4/176 (2%)
Frame = +3
Query: 141 LKMNNGRDMPAIGLGTYL-GFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 317
+ +NNG +MP +G GT G + N ++ ++ AI++GYR D A +Y E+
Sbjct: 4 ITLNNGLEMPIVGTGTNTYGKENNDYNGDLTNEIPELAS-AIELGYRSIDAAIMYRNEEL 62
Query: 318 IGEAVKMKVEEGVVKREDIFITTKLWNTQH---RRTEVAQAINDSLKKLGLDYIDLYLMH 488
+G + E V RE+ FITTK+ ++ + AI++SLK DY+DL L+H
Sbjct: 63 VGSVLA----ESKVPREEFFITTKIPASEEYISSKEATRAAIDNSLKNFQTDYLDLLLIH 118
Query: 489 WPIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
+PI V TW E+ G +K IG+SNF + L+ + + +KP
Sbjct: 119 FPI-------EDKVQLKNTWEVFEEYYEAGKLKAIGVSNFEENHLDELKEFAKVKP 167
>UniRef50_A4YQ04 Cluster: 2,5-diketo-D-gluconate reductase B; n=15;
Proteobacteria|Rep: 2,5-diketo-D-gluconate reductase B -
Bradyrhizobium sp. (strain ORS278)
Length = 273
Score = 89.8 bits (213), Expect = 5e-17
Identities = 59/163 (36%), Positives = 87/163 (53%), Gaps = 1/163 (0%)
Frame = +3
Query: 156 GRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVK 335
G +P +GLGT F G V RD V A+ +GYRH DTA +Y E IG A+
Sbjct: 8 GVRLPKLGLGT---FRMQGTV------CRDAVESALALGYRHIDTAEMYANEDAIGAALA 58
Query: 336 MKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP-IGLNAD 512
+ RED+ +TTK+W + +A + SLKKL LD++DLYL+HWP G+N
Sbjct: 59 A----AQIAREDLHVTTKVWPENLAPDAIRRAFDTSLKKLRLDFVDLYLIHWPATGMNLP 114
Query: 513 YSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKE 641
+ MET L ++ G + IG++NF L++ +++
Sbjct: 115 AA------METLMAL---KQEGRTRAIGVANFTVALLKQAVED 148
>UniRef50_Q2H7A8 Cluster: Putative uncharacterized protein; n=1;
Chaetomium globosum|Rep: Putative uncharacterized
protein - Chaetomium globosum (Soil fungus)
Length = 289
Score = 89.8 bits (213), Expect = 5e-17
Identities = 59/177 (33%), Positives = 94/177 (53%)
Frame = +3
Query: 126 MEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYE 305
M++P L++ +G +P + LG F Q G+V D+ I+ G+ H D A +Y
Sbjct: 1 MDIPLLRLRDGNQIP-LDLGDTT-FGQ-GLV--------DLTKAVIEKGFYHLDCAEMYG 49
Query: 306 TEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLM 485
TE+E+ A+K E V RE +FIT K+ ++ AI+ SL+K+ +Y DLYL+
Sbjct: 50 TEEEVAIAIK----ESGVPREKLFITNKV---AQGIDDIEAAIDQSLQKMQTNYFDLYLI 102
Query: 486 HWPIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
H P ++ S+ DF W+ +E Q+ G + IG+SN+ + +E LK T P
Sbjct: 103 HIPF-----FAKSEEDFQRAWKTMEGIQKAGKARSIGVSNYMRPHIEATLKGATSPP 154
>UniRef50_A7SGW6 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 264
Score = 89.4 bits (212), Expect = 7e-17
Identities = 54/170 (31%), Positives = 88/170 (51%)
Frame = +3
Query: 147 MNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGE 326
+N+GR MP GLG + + DV + A+ GYR DTA +Y+ E+E+G
Sbjct: 15 LNDGRKMPLFGLGVF----------RLETGCEDVCLFALKNGYRMLDTADIYQNEKEVGS 64
Query: 327 AVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLN 506
AV+ + +KREDI++TTKL ++ + + +S+KKL + Y+DL+L+H P N
Sbjct: 65 AVR----KSGLKREDIYVTTKLKPSEEGHSNALKYAKESIKKLDIGYVDLFLIHTPRPGN 120
Query: 507 ADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
+ + L + G+++ +G+SNF LE + K G P
Sbjct: 121 ---------IIAAYDALLTLKEEGLIRSVGVSNFGVHHLEELRKAGCRTP 161
>UniRef50_Q8EVT8 Cluster: Oxidoreductase-aldo/keto reductase family;
n=1; Mycoplasma penetrans|Rep: Oxidoreductase-aldo/keto
reductase family - Mycoplasma penetrans
Length = 299
Score = 88.6 bits (210), Expect = 1e-16
Identities = 58/178 (32%), Positives = 95/178 (53%), Gaps = 1/178 (0%)
Frame = +3
Query: 135 PSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQ 314
P L +N+G +P IGLGT ++ ++ + A+++G R FDTAS+Y E+
Sbjct: 35 PLLTLNDGYQIPIIGLGT---------TSLHNQTCKNAIKAALEIGIRLFDTASLYGNEK 85
Query: 315 EIGEAVKMKVEEGVVKREDIFITTKLW-NTQHRRTEVAQAINDSLKKLGLDYIDLYLMHW 491
E+GE ++ E + R +IF+ TKL+ Q E +AI ++L KL DYID+ L+H
Sbjct: 86 EVGETIR----ESNINRNEIFVITKLYPGAQFANPE--KAIEEALNKLNTDYIDMMLLHH 139
Query: 492 PIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAI 665
P +DV + ++ +E G +K +GLSN+ +++ L + IKP I
Sbjct: 140 P-------GENDV---KAYKAIEKYIEKGKIKSVGLSNWYIKEINSFLPQINIKPSLI 187
>UniRef50_Q11DV1 Cluster: Aldo/keto reductase; n=10;
Alphaproteobacteria|Rep: Aldo/keto reductase -
Mesorhizobium sp. (strain BNC1)
Length = 274
Score = 88.6 bits (210), Expect = 1e-16
Identities = 39/101 (38%), Positives = 65/101 (64%)
Frame = +3
Query: 192 LGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKRED 371
LGF GV + D ++ ++ A++ G+RHFDTA +Y+ E +G A+ E +RED
Sbjct: 14 LGF---GVFRMSDAEVERIIPAALEAGFRHFDTAQIYQNEAALGRAL----ERAGARRED 66
Query: 372 IFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWP 494
+F+TTK+W + + A ++++SL+KL +D +DL L+HWP
Sbjct: 67 LFLTTKVWVDNYSADKFAASVDESLEKLKVDQVDLLLLHWP 107
>UniRef50_A2QB88 Cluster: Contig An01c0460, complete genome.
precursor; n=1; Aspergillus niger|Rep: Contig An01c0460,
complete genome. precursor - Aspergillus niger
Length = 351
Score = 88.6 bits (210), Expect = 1e-16
Identities = 66/184 (35%), Positives = 94/184 (51%), Gaps = 21/184 (11%)
Frame = +3
Query: 168 PAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVE 347
PA+GLGT+ G N VK + V++A+ GYRH DTA+ Y E E+GEA+K
Sbjct: 47 PAVGLGTFQGDAGNRGVK-------EAVLQALRCGYRHIDTATAYGNEIEVGEAIK---- 95
Query: 348 EGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDY---IDLY------------- 479
E + RE+I +TTKL T HR ++V +A++ SL++L L+Y + LY
Sbjct: 96 ESRIPREEIIVTTKLAQTWHRVSDVERALDLSLERLQLNYGLSMHLYSASSYSVPHAYSP 155
Query: 480 -----LMHWPIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEG 644
+ P G D+ TW +E G +K IG+SNFN +LER+L
Sbjct: 156 GPDNNTIRHPNGKPIIDHELSRDYPSTWAAMESLVDKGKLKMIGVSNFNILKLERLLGSA 215
Query: 645 TIKP 656
I P
Sbjct: 216 RIPP 219
>UniRef50_A7D6Q0 Cluster: Aldo/keto reductase; n=1; Halorubrum
lacusprofundi ATCC 49239|Rep: Aldo/keto reductase -
Halorubrum lacusprofundi ATCC 49239
Length = 309
Score = 88.6 bits (210), Expect = 1e-16
Identities = 53/164 (32%), Positives = 85/164 (51%)
Frame = +3
Query: 132 VPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETE 311
+P+ + +G +PA+GLGTY D D Q+ D V A+ GY H DTA Y E
Sbjct: 34 IPTQTLPSGDTLPALGLGTY-ALD--------DDQIADSVRAALSSGYTHIDTAEGYHNE 84
Query: 312 QEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHW 491
+ IGE + R+D+F+T+K+ + Q+ SL++L DY+DLYL+HW
Sbjct: 85 EAIGEVL------AEYDRDDVFLTSKVLAKNLGYESLIQSCEASLERLETDYLDLYLIHW 138
Query: 492 PIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQL 623
P + + E+ + + + G+V+ +G+SNF+ QL
Sbjct: 139 P--------NPAISLRESLQAMAELHDRGLVRNVGVSNFSAYQL 174
>UniRef50_Q14LU6 Cluster: Putative aldo/keto reductase
oxidoreductase protein; n=1; Spiroplasma citri|Rep:
Putative aldo/keto reductase oxidoreductase protein -
Spiroplasma citri
Length = 138
Score = 88.2 bits (209), Expect = 2e-16
Identities = 46/115 (40%), Positives = 72/115 (62%)
Frame = +3
Query: 141 LKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI 320
LK+ NG ++P IGLGTY D++ V ++ ++ A+ GYRH DTA +Y E+ I
Sbjct: 8 LKLFNGVEIPLIGLGTYKMTDEHEVYQA--------IITALQNGYRHIDTAQIYGNEELI 59
Query: 321 GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLM 485
G+A+K + V R++IF+T+K+WN H+ Q I++ LK+L DY+DL L+
Sbjct: 60 GKAIK----DSGVPRKEIFLTSKIWNANHKYDAALQEIDNILKRLDTDYLDLCLV 110
>UniRef50_Q7XY49 Cluster: Mannose 6-phosphate reductase; n=1;
Griffithsia japonica|Rep: Mannose 6-phosphate reductase
- Griffithsia japonica (Red alga)
Length = 174
Score = 88.2 bits (209), Expect = 2e-16
Identities = 49/131 (37%), Positives = 72/131 (54%)
Frame = +3
Query: 126 MEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYE 305
M + + +G MP G GT+ K+ ++ V A+ GYRH D A+VY
Sbjct: 1 MSTNTATLQSGAKMPLNGFGTW---------KASVEETEQAVTAALRAGYRHIDCAAVYW 51
Query: 306 TEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLM 485
E +G A+ + GVVKRED+FIT+K+WNT H +V + SLK +DY DL+L+
Sbjct: 52 NEAAVGTAISKAISGGVVKREDLFITSKVWNTCHATDKVVDSCRQSLKDHQVDYFDLFLV 111
Query: 486 HWPIGLNADYS 518
IG+ ++YS
Sbjct: 112 R-DIGV-SNYS 120
>UniRef50_A3WP89 Cluster: Aldo/keto reductase; n=1; Idiomarina
baltica OS145|Rep: Aldo/keto reductase - Idiomarina
baltica OS145
Length = 263
Score = 87.8 bits (208), Expect = 2e-16
Identities = 49/140 (35%), Positives = 76/140 (54%)
Frame = +3
Query: 210 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 389
G + + ++L D+V AID+GY H DTA Y E ++G+A+ +D+F+TTK
Sbjct: 8 GTFRLEGQELTDLVSAAIDMGYEHIDTAQFYGNEADVGKALAQHT------NKDVFVTTK 61
Query: 390 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQ 569
+W + +V ++ S KL D IDL L+HWP + +V ET L+ AQ
Sbjct: 62 VWYEKLAYQDVLDSLQVSRDKLQRDTIDLALIHWP------SPNDEVPVEETLDALQKAQ 115
Query: 570 RMGIVKGIGLSNFNKQQLER 629
+ G++K +G+SNF L R
Sbjct: 116 QDGLIKHLGVSNFTIDLLNR 135
>UniRef50_Q4PHK0 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 355
Score = 87.8 bits (208), Expect = 2e-16
Identities = 67/206 (32%), Positives = 104/206 (50%), Gaps = 31/206 (15%)
Frame = +3
Query: 138 SLKMNNGRDMPAIGLGTYL---GFDQNGVVKSKDKQLRDVV-----MRAIDVGYRHF--- 284
+ K+N G ++P IGLGT+ G V + R +V + + +GY
Sbjct: 13 TFKLNTGAEIPVIGLGTWQSAPGEVAKAVESAIKAGYRHIVSMLTSLLTLTLGYVALHPL 72
Query: 285 -------DTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDS 443
D A +Y E E+G+ +K V R ++F+TTK+W T HR+ E +++S
Sbjct: 73 YIPFLAKDAAWIYGNENEVGQGIKASG----VPRSELFVTTKIWCTYHRQPEAC--LDES 126
Query: 444 LKKLGLDYIDLYLMHWP----------IGLNADYSHS-DVDFM--ETWRGLEDAQRMGIV 584
L++LGLDY+DL L+HWP I LN D S + D D+ +TW +E G
Sbjct: 127 LQRLGLDYVDLLLVHWPVPLVKRGDEKIPLNEDGSRAIDRDWSPEQTWELMEKLPATGKT 186
Query: 585 KGIGLSNFNKQQLERVLKEGTIKPDA 662
K IG+SN++ L+++L + I P A
Sbjct: 187 KAIGVSNWSIAFLDKLLAKAKIVPAA 212
>UniRef50_Q07551 Cluster: NADPH-dependent alpha-keto amide
reductase; n=4; Saccharomycetales|Rep: NADPH-dependent
alpha-keto amide reductase - Saccharomyces cerevisiae
(Baker's yeast)
Length = 312
Score = 87.0 bits (206), Expect = 4e-16
Identities = 54/173 (31%), Positives = 88/173 (50%), Gaps = 3/173 (1%)
Frame = +3
Query: 147 MNNGRDMPAIGL-GTYLGFDQNGVVKSK-DKQLRDVVMRAIDV-GYRHFDTASVYETEQE 317
+NNG +PAI + GT + +N + L + ++ A+ + G H D A +Y T E
Sbjct: 10 LNNGNKIPAIAIIGTGTRWYKNEETDATFSNSLVEQIVYALKLPGIIHIDAAEIYRTYPE 69
Query: 318 IGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPI 497
+G+A+ + + R IF+T K A ++ +LKK+G DY+DLYL+H P
Sbjct: 70 VGKALSLTEKP----RNAIFLTDKYSPQIKMSDSPADGLDLALKKMGTDYVDLYLLHSPF 125
Query: 498 GLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
+ + E W+ +E + G K IG+SNF + L+R+LK +KP
Sbjct: 126 ---VSKEVNGLSLEEAWKDMEQLYKSGKAKNIGVSNFAVEDLQRILKVAEVKP 175
>UniRef50_A2RMU6 Cluster: Oxidoreductase, aldo/keto reductase
family; n=3; Lactococcus lactis|Rep: Oxidoreductase,
aldo/keto reductase family - Lactococcus lactis subsp.
cremoris (strain MG1363)
Length = 281
Score = 86.6 bits (205), Expect = 5e-16
Identities = 57/173 (32%), Positives = 90/173 (52%)
Frame = +3
Query: 147 MNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGE 326
+N+G +P GLG Y + + + V A+ +GYRH DTA Y+ E+ +G
Sbjct: 7 LNDGNIIPQFGLGVYQ--------IPEGEATENAVKEALRLGYRHIDTAHAYQNERSVGR 58
Query: 327 AVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLN 506
A+ G+ E I+IT+KLW + + + +QAI L+ L L IDL L+H +G
Sbjct: 59 AIH---SSGIPISE-IWITSKLWPSDY--DDASQAIERMLELLNLKQIDLLLLHQQVG-- 110
Query: 507 ADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKPDAI 665
++ + W LE+A + G VK IG+SNF+ ++L + IKP A+
Sbjct: 111 --------NYRKAWIALENAVKSGKVKSIGISNFDGERLVDLFNFADIKPSAL 155
>UniRef50_UPI000155CAC7 Cluster: PREDICTED: hypothetical protein;
n=1; Ornithorhynchus anatinus|Rep: PREDICTED:
hypothetical protein - Ornithorhynchus anatinus
Length = 419
Score = 86.2 bits (204), Expect = 6e-16
Identities = 52/151 (34%), Positives = 81/151 (53%), Gaps = 1/151 (0%)
Frame = +3
Query: 114 LASTMEVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAI-DVGYRHFDT 290
L + VP++ + NG ++P +GLGT D V+ A+ + G RH DT
Sbjct: 6 LGKGLPVPTVPLANGLNIPILGLGT----------SHVGGYSHDAVIYALKECGIRHIDT 55
Query: 291 ASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYI 470
A Y E +G+A+ +E VKRE+++ITTKLW T + Q+ +S +LG++Y+
Sbjct: 56 AKRYGCELLLGKAI----QESGVKREELWITTKLWLTDYGYESAKQSCLESCNRLGVEYL 111
Query: 471 DLYLMHWPIGLNADYSHSDVDFMETWRGLED 563
DL+L+HWP S + ETWR +E+
Sbjct: 112 DLFLIHWPDAQLPGKSSREAR-AETWRAMEE 141
>UniRef50_Q3CZS2 Cluster: Oxidoreductase, aldo/keto reductase
family; n=2; Streptococcus agalactiae|Rep:
Oxidoreductase, aldo/keto reductase family -
Streptococcus agalactiae H36B
Length = 245
Score = 86.2 bits (204), Expect = 6e-16
Identities = 57/170 (33%), Positives = 88/170 (51%)
Frame = +3
Query: 147 MNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGE 326
+NNG +P++G G + D +S V+ A+ VGYR DTAS Y E+ +G
Sbjct: 9 LNNGVKIPSLGFGVFQIDDPLECEQS--------VLDALQVGYRLIDTASGYLNEEAVGR 60
Query: 327 AVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLN 506
A+K + + R++IF+ TKLW + AI+ +LK+L LDYI+LYL+H P+G
Sbjct: 61 AIK----KSGIPRKEIFVVTKLWIQDASEEKAGPAIDRALKRLQLDYINLYLIHQPMG-- 114
Query: 507 ADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVLKEGTIKP 656
D+ R LE A IG+SNF+ +++ ++ I P
Sbjct: 115 --------DYYGACRALEKAYEERKALAIGVSNFSNGRVQDLILHNKIIP 156
>UniRef50_A4FEB9 Cluster: 2,5-diketo-D-gluconic acid reductase; n=1;
Saccharopolyspora erythraea NRRL 2338|Rep:
2,5-diketo-D-gluconic acid reductase - Saccharopolyspora
erythraea (strain NRRL 23338)
Length = 159
Score = 86.2 bits (204), Expect = 6e-16
Identities = 44/121 (36%), Positives = 69/121 (57%)
Frame = +3
Query: 132 VPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETE 311
VP++ +NNG +MP +G G + + + + V A++ GYR DTA+ Y E
Sbjct: 4 VPTVTLNNGVEMPQLGYGVF---------QVPEDETAAAVGAALEAGYRSIDTAAAYGNE 54
Query: 312 QEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHW 491
+G A+ G+ R+++F+TTKLWN +A + SL+ LGLD++DLYL+HW
Sbjct: 55 AAVGRAL---AGSGLA-RDELFVTTKLWNADQGYDNALRAFDTSLELLGLDHLDLYLIHW 110
Query: 492 P 494
P
Sbjct: 111 P 111
>UniRef50_Q5V663 Cluster: Aldehyde reductase; n=6;
Halobacteriaceae|Rep: Aldehyde reductase - Haloarcula
marismortui (Halobacterium marismortui)
Length = 279
Score = 85.8 bits (203), Expect = 8e-16
Identities = 49/157 (31%), Positives = 78/157 (49%)
Frame = +3
Query: 165 MPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKV 344
MP +GLGT+ D +Q + V A++ GYRH DTA Y+ E +G+ +
Sbjct: 17 MPMLGLGTWQNEDA--------EQCAESVRTALEAGYRHIDTAQAYDNESAVGDGIAA-- 66
Query: 345 EEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHS 524
V R+DIF+ TK+W + +V + +SL KLG+D +DL +HW G +Y
Sbjct: 67 --ADVDRDDIFLATKVWISNLSHDDVIETTEESLDKLGVDSVDLLYVHWAAG---EYEPE 121
Query: 525 DVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL 635
ET ++ G++ +G+SNF +E +
Sbjct: 122 -----ETLPAFDELVDRGLIDNVGVSNFEPHHVETAM 153
>UniRef50_Q16CS5 Cluster: 2,5-diketo-D-gluconic acid reductase B,
putative; n=3; Bacteria|Rep: 2,5-diketo-D-gluconic acid
reductase B, putative - Roseobacter denitrificans
(strain ATCC 33942 / OCh 114) (Erythrobactersp. (strain
OCh 114)) (Roseobacter denitrificans)
Length = 272
Score = 85.4 bits (202), Expect = 1e-15
Identities = 48/138 (34%), Positives = 74/138 (53%)
Frame = +3
Query: 210 GVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTK 389
G K RD ++ A +VGYR FDTA +Y E E G A+K E G+ R+ + +TTK
Sbjct: 14 GTYPLKGTACRDAILTAAEVGYRAFDTAQMYRNEAETGAALK---ETGI-PRDTLCVTTK 69
Query: 390 LWNTQHRRTEVAQAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQ 569
+ N + ++ ++ SLK L LDY+D+ L+HWP +D + LE A
Sbjct: 70 VENDNYDESKFLASVEASLKALQLDYVDVLLLHWP--------PADFQIEGSLTLLEQAH 121
Query: 570 RMGIVKGIGLSNFNKQQL 623
+ G+ + IG+SN+ Q +
Sbjct: 122 KRGMARNIGVSNYTVQMM 139
>UniRef50_Q68A33 Cluster: Aldo-keto reductase 1a; n=1; Ciona
intestinalis|Rep: Aldo-keto reductase 1a - Ciona
intestinalis (Transparent sea squirt)
Length = 584
Score = 85.4 bits (202), Expect = 1e-15
Identities = 58/184 (31%), Positives = 89/184 (48%), Gaps = 14/184 (7%)
Frame = +3
Query: 129 EVPSLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYET 308
E+P +K+N+G MP IGLGT F + + V A+ +GYR DTA +Y
Sbjct: 256 EIPDVKLNSGYMMPPIGLGTARLFSKT----------YETVKTALKLGYRMLDTAQIYTG 305
Query: 309 EQEIG-------EAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLGLDY 467
E +I E + + + V R ++FI TKL + + +SLKKL DY
Sbjct: 306 EDKINNFKVSSEEEIGRAIADSDVPRSELFIVTKLAPESMEKENAIAKVEESLKKLRTDY 365
Query: 468 IDLYLMHWPIGLNADYSHSDVDFME-------TWRGLEDAQRMGIVKGIGLSNFNKQQLE 626
IDL L+H ++ D D E W+ +E+ Q G+V+ IG+SN + L+
Sbjct: 366 IDLLLIH-DFYMSTACGPDDTDLPECKNNPFLAWKTMEEMQAKGLVRSIGVSNIYIEDLQ 424
Query: 627 RVLK 638
++K
Sbjct: 425 YLVK 428
>UniRef50_Q5KKZ8 Cluster: Aldo-keto reductase, putative; n=2;
Filobasidiella neoformans|Rep: Aldo-keto reductase,
putative - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 293
Score = 85.4 bits (202), Expect = 1e-15
Identities = 59/170 (34%), Positives = 86/170 (50%), Gaps = 7/170 (4%)
Frame = +3
Query: 138 SLKMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQE 317
++K+ +G +P +G G Y +++ K+ D V +AID GYRH DTA Y E+
Sbjct: 8 TIKLASGNLIPRLGFGVY---------QARSKECEDAVKKAIDTGYRHVDTAQAYHNEEN 58
Query: 318 IGEAVKMKVEEGVVKREDIFITTKLW--NTQHRRTEVAQAINDSLKKL---GLD--YIDL 476
+G A++ V R +F+T+K +T + TEV + SLKK+ G D YIDL
Sbjct: 59 VGRAIR----NSGVPRPSVFLTSKYMPSHTVYSPTEVLDVVRKSLKKVDRCGDDKPYIDL 114
Query: 477 YLMHWPIGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLE 626
L+H P G + W L AQ+ G VK IG+SNF L+
Sbjct: 115 MLIHAPWG-------GEEGRKNNWEALTIAQKEGWVKDIGVSNFGIHHLK 157
>UniRef50_A3LWP0 Cluster: Aldo/keto reductase; n=7;
Saccharomycetales|Rep: Aldo/keto reductase - Pichia
stipitis (Yeast)
Length = 323
Score = 85.4 bits (202), Expect = 1e-15
Identities = 56/141 (39%), Positives = 79/141 (56%), Gaps = 6/141 (4%)
Frame = +3
Query: 234 QLRDVVMRAIDVGYRHFDTASVYETEQEIGEAVKMKVEEGVVKREDIFITTKLWNTQHRR 413
+L D ++ A++ GY H DTA VY T E+ AVK + G+ RED+FITTK T R
Sbjct: 51 ELVDSILLALENGYNHIDTAEVYTTHPEVAAAVK---KSGIA-REDLFITTKY--TPGFR 104
Query: 414 TEVA------QAINDSLKKLGLDYIDLYLMHWPIGLNADYSHSDVDFMETWRGLEDAQRM 575
T A + I+ +LK+L DY+DL+L+H P S W + DA++
Sbjct: 105 TFPAISSGPTEFIDRALKELETDYVDLFLIHSPF-FEEKVSRGQT-LESAWAEVIDAKKA 162
Query: 576 GIVKGIGLSNFNKQQLERVLK 638
G V+ IG+SNF+K+ LER K
Sbjct: 163 GKVRHIGVSNFSKEHLERTFK 183
>UniRef50_Q75E75 Cluster: ABL209Cp; n=1; Eremothecium gossypii|Rep:
ABL209Cp - Ashbya gossypii (Yeast) (Eremothecium
gossypii)
Length = 310
Score = 85.0 bits (201), Expect = 1e-15
Identities = 55/167 (32%), Positives = 92/167 (55%), Gaps = 3/167 (1%)
Frame = +3
Query: 144 KMNNGRDMPAIGLGTYLGFDQNGVVKSKDKQLRDVVMRAIDVGYRHFDTASVYETEQEI- 320
++++G +P++GLG Y + ++ ++D+V A++VGYR FD+A Y E +
Sbjct: 14 RLSDGTQIPSVGLGVY---------QVSEQTVQDLVYEALEVGYRLFDSAQAYHNEDGVA 64
Query: 321 -GEAVKMKVEEGVVKREDIFITTKLWNTQHRRTEVAQAINDSLKKLG-LDYIDLYLMHWP 494
G A +K G +RED++ TTK+ H +++ SL G L YIDL L+H P
Sbjct: 65 RGIAAWLKHAPG-RRREDVYFTTKINTQNHGYEATKKSLEKSLHAAGPLGYIDLVLVHAP 123
Query: 495 IGLNADYSHSDVDFMETWRGLEDAQRMGIVKGIGLSNFNKQQLERVL 635
+ +D + + TW+ LE+A G V+ IG+SN+ +Q L +L
Sbjct: 124 M---SDRTRR----LGTWQALEEAVVEGQVRSIGVSNYGQQHLSELL 163
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 660,467,215
Number of Sequences: 1657284
Number of extensions: 13193541
Number of successful extensions: 39821
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 37611
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 38941
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 50826451017
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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