SilkBase IMG001 IMG002 IMG003 IMG005 IMG006 IMG007 IMG008 IMG009 kuwako IMG010 IMG011 IMG012

Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= bmov11b03
         (522 letters)

Database: human 
           237,096 sequences; 76,859,062 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

BC053651-1|AAH53651.1|  887|Homo sapiens phosphoinositide-3-kina...   208   1e-53
BC033004-1|AAH33004.1|  887|Homo sapiens phosphoinositide-3-kina...   208   1e-53
Z46973-1|CAA87094.1|  887|Homo sapiens phosphatidylinositol 3-ki...   205   6e-53
Z29090-1|CAA82333.1| 1068|Homo sapiens phosphatidylinositol 3-ki...    41   0.003
U79143-1|AAB39753.1| 1068|Homo sapiens phosphoinositide 3'-hydro...    41   0.003
BC113603-1|AAI13604.1| 1068|Homo sapiens phosphoinositide-3-kina...    41   0.003
BC113601-1|AAI13602.1| 1068|Homo sapiens phosphoinositide-3-kina...    41   0.003
AB210020-1|BAE06102.1| 1069|Homo sapiens PIK3CA variant protein ...    41   0.003
Y13367-1|CAA73797.1| 1686|Homo sapiens phosphoinositide 3-kinase...    38   0.021
BC113658-1|AAI13659.1| 1686|Homo sapiens phosphoinositide-3-kina...    38   0.021
X83368-1|CAA58284.1| 1101|Homo sapiens idem protein.                   35   0.15 
BC035683-1|AAH35683.1| 1102|Homo sapiens PIK3CG protein protein.       35   0.15 
AF327656-1|AAG61115.1| 1102|Homo sapiens phosphoinositide-3-kina...    35   0.15 
AC005018-1|AAQ96873.1| 1102|Homo sapiens unknown protein.              35   0.15 
Y13892-1|CAA74194.1| 1609|Homo sapiens PI-3 kinase protein.            35   0.20 
BC132876-1|AAI32877.1| 1634|Homo sapiens phosphoinositide-3-kina...    35   0.20 
AL606489-4|CAI16572.1| 1634|Homo sapiens phosphoinositide-3-kina...    35   0.20 
AB210006-1|BAE06088.1| 1645|Homo sapiens PIK3C2B variant protein...    35   0.20 
Y11312-1|CAA72168.1| 1634|Homo sapiens phosphoinositide 3-kinase...    34   0.35 
AF012872-1|AAD13352.1| 2044|Homo sapiens phosphatidylinositol 4-...    31   3.2  
AB210002-1|BAE06084.1| 2121|Homo sapiens PIK4CA variant protein ...    31   3.2  

>BC053651-1|AAH53651.1|  887|Homo sapiens phosphoinositide-3-kinase,
           class 3 protein.
          Length = 887

 Score =  208 bits (507), Expect = 1e-53
 Identities = 88/133 (66%), Positives = 111/133 (83%)
 Frame = +3

Query: 123 DKFYYVYSSSLDYKVEIKIGTLEGKRTKPEYDKLLSDPMLKFSGLYQDGCSDLYVTCQIL 302
           +KF+Y+YS  LD  V++KIG+LEGKR +  Y  +L DPMLKFSGLYQ+ CSDLYVTCQ+ 
Sbjct: 5   EKFHYIYSCDLDINVQLKIGSLEGKREQKSYKAVLEDPMLKFSGLYQETCSDLYVTCQVF 64

Query: 303 SDGEPLALPVMTTYKAFTTRWNWNEWVTLPVYYSDLPRNAILAMTIYDCAGPGKVMVVGG 482
           ++G+PLALPV T+YKAF+TRWNWNEW+ LPV Y DLPRNA +A+TI+D  GPGK + VGG
Sbjct: 65  AEGKPLALPVRTSYKAFSTRWNWNEWLKLPVKYPDLPRNAQVALTIWDVYGPGKAVPVGG 124

Query: 483 TTISIFGKHGMLR 521
           TT+S+FGK+GM R
Sbjct: 125 TTVSLFGKYGMFR 137


>BC033004-1|AAH33004.1|  887|Homo sapiens phosphoinositide-3-kinase,
           class 3 protein.
          Length = 887

 Score =  208 bits (507), Expect = 1e-53
 Identities = 88/133 (66%), Positives = 111/133 (83%)
 Frame = +3

Query: 123 DKFYYVYSSSLDYKVEIKIGTLEGKRTKPEYDKLLSDPMLKFSGLYQDGCSDLYVTCQIL 302
           +KF+Y+YS  LD  V++KIG+LEGKR +  Y  +L DPMLKFSGLYQ+ CSDLYVTCQ+ 
Sbjct: 5   EKFHYIYSCDLDINVQLKIGSLEGKREQKSYKAVLEDPMLKFSGLYQETCSDLYVTCQVF 64

Query: 303 SDGEPLALPVMTTYKAFTTRWNWNEWVTLPVYYSDLPRNAILAMTIYDCAGPGKVMVVGG 482
           ++G+PLALPV T+YKAF+TRWNWNEW+ LPV Y DLPRNA +A+TI+D  GPGK + VGG
Sbjct: 65  AEGKPLALPVRTSYKAFSTRWNWNEWLKLPVKYPDLPRNAQVALTIWDVYGPGKAVPVGG 124

Query: 483 TTISIFGKHGMLR 521
           TT+S+FGK+GM R
Sbjct: 125 TTVSLFGKYGMFR 137


>Z46973-1|CAA87094.1|  887|Homo sapiens phosphatidylinositol
           3-kinase protein.
          Length = 887

 Score =  205 bits (501), Expect = 6e-53
 Identities = 87/133 (65%), Positives = 111/133 (83%)
 Frame = +3

Query: 123 DKFYYVYSSSLDYKVEIKIGTLEGKRTKPEYDKLLSDPMLKFSGLYQDGCSDLYVTCQIL 302
           +KF+Y+YS  LD  V++KIG+LEGKR +  Y+ +L DPMLKFSGLYQ+ CSDLYVTCQ+ 
Sbjct: 5   EKFHYIYSCDLDINVQLKIGSLEGKREQKSYNAVLEDPMLKFSGLYQETCSDLYVTCQVF 64

Query: 303 SDGEPLALPVMTTYKAFTTRWNWNEWVTLPVYYSDLPRNAILAMTIYDCAGPGKVMVVGG 482
           ++G+P ALPV T+YKAF+TRWNWNEW+ LPV Y DLPRNA +A+TI+D  GPGK + VGG
Sbjct: 65  AEGKPSALPVRTSYKAFSTRWNWNEWLKLPVKYPDLPRNAQVALTIWDVYGPGKAVPVGG 124

Query: 483 TTISIFGKHGMLR 521
           TT+S+FGK+GM R
Sbjct: 125 TTVSLFGKYGMSR 137


>Z29090-1|CAA82333.1| 1068|Homo sapiens phosphatidylinositol
           3-kinase protein.
          Length = 1068

 Score = 40.7 bits (91), Expect = 0.003
 Identities = 22/59 (37%), Positives = 29/59 (49%)
 Frame = +3

Query: 279 LYVTCQILSDGEPLALPVMTTYKAFTTRWNWNEWVTLPVYYSDLPRNAILAMTIYDCAG 455
           +YV   I   GEPL   V  T +   +   WNEW+   +Y  DLPR A L ++I    G
Sbjct: 354 IYVRTGIYHGGEPLCDNV-NTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKG 411


>U79143-1|AAB39753.1| 1068|Homo sapiens phosphoinositide
           3'-hydroxykinase p110-alpha subunit protein.
          Length = 1068

 Score = 40.7 bits (91), Expect = 0.003
 Identities = 22/59 (37%), Positives = 29/59 (49%)
 Frame = +3

Query: 279 LYVTCQILSDGEPLALPVMTTYKAFTTRWNWNEWVTLPVYYSDLPRNAILAMTIYDCAG 455
           +YV   I   GEPL   V  T +   +   WNEW+   +Y  DLPR A L ++I    G
Sbjct: 354 IYVRTGIYHGGEPLCDNV-NTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKG 411


>BC113603-1|AAI13604.1| 1068|Homo sapiens phosphoinositide-3-kinase,
           catalytic, alpha polypeptide protein.
          Length = 1068

 Score = 40.7 bits (91), Expect = 0.003
 Identities = 22/59 (37%), Positives = 29/59 (49%)
 Frame = +3

Query: 279 LYVTCQILSDGEPLALPVMTTYKAFTTRWNWNEWVTLPVYYSDLPRNAILAMTIYDCAG 455
           +YV   I   GEPL   V  T +   +   WNEW+   +Y  DLPR A L ++I    G
Sbjct: 354 IYVRTGIYHGGEPLCDNV-NTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKG 411


>BC113601-1|AAI13602.1| 1068|Homo sapiens phosphoinositide-3-kinase,
           catalytic, alpha polypeptide protein.
          Length = 1068

 Score = 40.7 bits (91), Expect = 0.003
 Identities = 22/59 (37%), Positives = 29/59 (49%)
 Frame = +3

Query: 279 LYVTCQILSDGEPLALPVMTTYKAFTTRWNWNEWVTLPVYYSDLPRNAILAMTIYDCAG 455
           +YV   I   GEPL   V  T +   +   WNEW+   +Y  DLPR A L ++I    G
Sbjct: 354 IYVRTGIYHGGEPLCDNV-NTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKG 411


>AB210020-1|BAE06102.1| 1069|Homo sapiens PIK3CA variant protein
           protein.
          Length = 1069

 Score = 40.7 bits (91), Expect = 0.003
 Identities = 22/59 (37%), Positives = 29/59 (49%)
 Frame = +3

Query: 279 LYVTCQILSDGEPLALPVMTTYKAFTTRWNWNEWVTLPVYYSDLPRNAILAMTIYDCAG 455
           +YV   I   GEPL   V  T +   +   WNEW+   +Y  DLPR A L ++I    G
Sbjct: 355 IYVRTGIYHGGEPLCDNV-NTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKG 412


>Y13367-1|CAA73797.1| 1686|Homo sapiens phosphoinositide 3-kinase
           protein.
          Length = 1686

 Score = 37.9 bits (84), Expect = 0.021
 Identities = 17/58 (29%), Positives = 31/58 (53%), Gaps = 4/58 (6%)
 Frame = +3

Query: 282 YVTCQILSDGEPLALPVMT----TYKAFTTRWNWNEWVTLPVYYSDLPRNAILAMTIY 443
           Y+ C +  +G+ L  P+ +    TYK F     W+E +  P+  S LP  ++L +T++
Sbjct: 708 YLICSLSHNGKDLFKPIQSKKVGTYKNFFYLIKWDELIIFPIQISQLPLESVLHLTLF 765


>BC113658-1|AAI13659.1| 1686|Homo sapiens phosphoinositide-3-kinase,
           class 2, alpha polypeptide protein.
          Length = 1686

 Score = 37.9 bits (84), Expect = 0.021
 Identities = 17/58 (29%), Positives = 31/58 (53%), Gaps = 4/58 (6%)
 Frame = +3

Query: 282 YVTCQILSDGEPLALPVMT----TYKAFTTRWNWNEWVTLPVYYSDLPRNAILAMTIY 443
           Y+ C +  +G+ L  P+ +    TYK F     W+E +  P+  S LP  ++L +T++
Sbjct: 708 YLICSLSHNGKDLFKPIQSKKVGTYKNFFYLIKWDELIIFPIQISQLPLESVLHLTLF 765


>X83368-1|CAA58284.1| 1101|Homo sapiens idem protein.
          Length = 1101

 Score = 35.1 bits (77), Expect = 0.15
 Identities = 15/48 (31%), Positives = 24/48 (50%)
 Frame = +3

Query: 300 LSDGEPLALPVMTTYKAFTTRWNWNEWVTLPVYYSDLPRNAILAMTIY 443
           +  G+ +     T+ K FT    WN W+   +   DLP+ A+L + IY
Sbjct: 386 IQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKIKDLPKGALLNLQIY 433


>BC035683-1|AAH35683.1| 1102|Homo sapiens PIK3CG protein protein.
          Length = 1102

 Score = 35.1 bits (77), Expect = 0.15
 Identities = 15/48 (31%), Positives = 24/48 (50%)
 Frame = +3

Query: 300 LSDGEPLALPVMTTYKAFTTRWNWNEWVTLPVYYSDLPRNAILAMTIY 443
           +  G+ +     T+ K FT    WN W+   +   DLP+ A+L + IY
Sbjct: 387 IQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKIKDLPKGALLNLQIY 434


>AF327656-1|AAG61115.1| 1102|Homo sapiens phosphoinositide-3-kinase
           gamma catalytic subunit protein.
          Length = 1102

 Score = 35.1 bits (77), Expect = 0.15
 Identities = 15/48 (31%), Positives = 24/48 (50%)
 Frame = +3

Query: 300 LSDGEPLALPVMTTYKAFTTRWNWNEWVTLPVYYSDLPRNAILAMTIY 443
           +  G+ +     T+ K FT    WN W+   +   DLP+ A+L + IY
Sbjct: 387 IQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKIKDLPKGALLNLQIY 434


>AC005018-1|AAQ96873.1| 1102|Homo sapiens unknown protein.
          Length = 1102

 Score = 35.1 bits (77), Expect = 0.15
 Identities = 15/48 (31%), Positives = 24/48 (50%)
 Frame = +3

Query: 300 LSDGEPLALPVMTTYKAFTTRWNWNEWVTLPVYYSDLPRNAILAMTIY 443
           +  G+ +     T+ K FT    WN W+   +   DLP+ A+L + IY
Sbjct: 387 IQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIKIKDLPKGALLNLQIY 434


>Y13892-1|CAA74194.1| 1609|Homo sapiens PI-3 kinase protein.
          Length = 1609

 Score = 34.7 bits (76), Expect = 0.20
 Identities = 17/60 (28%), Positives = 29/60 (48%), Gaps = 4/60 (6%)
 Frame = +3

Query: 276 DLYVTCQILSDGEPLALPVMTTYKAFTTRWN----WNEWVTLPVYYSDLPRNAILAMTIY 443
           D Y++C +   G+ L  P+ T    F+        W++ +  PV  + LPR  +L  T+Y
Sbjct: 626 DFYLSCSLSHGGKELCSPLQTRRAHFSKYLFHLIVWDQQICFPVQVNRLPRETLLCATLY 685


>BC132876-1|AAI32877.1| 1634|Homo sapiens phosphoinositide-3-kinase,
           class 2, beta polypeptide protein.
          Length = 1634

 Score = 34.7 bits (76), Expect = 0.20
 Identities = 17/60 (28%), Positives = 29/60 (48%), Gaps = 4/60 (6%)
 Frame = +3

Query: 276 DLYVTCQILSDGEPLALPVMTTYKAFTTRWN----WNEWVTLPVYYSDLPRNAILAMTIY 443
           D Y++C +   G+ L  P+ T    F+        W++ +  PV  + LPR  +L  T+Y
Sbjct: 651 DFYLSCSLSHGGKELCSPLQTRRAHFSKYLFHLIVWDQQICFPVQVNRLPRETLLCATLY 710


>AL606489-4|CAI16572.1| 1634|Homo sapiens phosphoinositide-3-kinase,
           class 2, beta polypeptide protein.
          Length = 1634

 Score = 34.7 bits (76), Expect = 0.20
 Identities = 17/60 (28%), Positives = 29/60 (48%), Gaps = 4/60 (6%)
 Frame = +3

Query: 276 DLYVTCQILSDGEPLALPVMTTYKAFTTRWN----WNEWVTLPVYYSDLPRNAILAMTIY 443
           D Y++C +   G+ L  P+ T    F+        W++ +  PV  + LPR  +L  T+Y
Sbjct: 651 DFYLSCSLSHGGKELCSPLQTRRAHFSKYLFHLIVWDQQICFPVQVNRLPRETLLCATLY 710


>AB210006-1|BAE06088.1| 1645|Homo sapiens PIK3C2B variant protein
           protein.
          Length = 1645

 Score = 34.7 bits (76), Expect = 0.20
 Identities = 17/60 (28%), Positives = 29/60 (48%), Gaps = 4/60 (6%)
 Frame = +3

Query: 276 DLYVTCQILSDGEPLALPVMTTYKAFTTRWN----WNEWVTLPVYYSDLPRNAILAMTIY 443
           D Y++C +   G+ L  P+ T    F+        W++ +  PV  + LPR  +L  T+Y
Sbjct: 662 DFYLSCSLSHGGKELCSPLQTRRAHFSKYLFHLIVWDQQICFPVQVNRLPRETLLCATLY 721


>Y11312-1|CAA72168.1| 1634|Homo sapiens phosphoinositide 3-kinase
           protein.
          Length = 1634

 Score = 33.9 bits (74), Expect = 0.35
 Identities = 16/60 (26%), Positives = 29/60 (48%), Gaps = 4/60 (6%)
 Frame = +3

Query: 276 DLYVTCQILSDGEPLALPVMTTYKAFTTRWN----WNEWVTLPVYYSDLPRNAILAMTIY 443
           D Y++C +   G+ +  P+ T    F+        W++ +  PV  + LPR  +L  T+Y
Sbjct: 651 DFYLSCSLSHGGKDMCSPLQTRRAHFSKYLFHLIVWDQQICFPVQVNRLPRETLLCATLY 710


>AF012872-1|AAD13352.1| 2044|Homo sapiens phosphatidylinositol
           4-kinase 230 protein.
          Length = 2044

 Score = 30.7 bits (66), Expect = 3.2
 Identities = 12/32 (37%), Positives = 20/32 (62%)
 Frame = -1

Query: 279 SLSIHLGKVLRISTSDLIVVCHIPV*FSCLQG 184
           +L I L + L+  TS  +++ H+P+   CLQG
Sbjct: 399 NLCIKLSEKLQSKTSSKVIIAHLPLLICCLQG 430


>AB210002-1|BAE06084.1| 2121|Homo sapiens PIK4CA variant protein
           protein.
          Length = 2121

 Score = 30.7 bits (66), Expect = 3.2
 Identities = 12/32 (37%), Positives = 20/32 (62%)
 Frame = -1

Query: 279 SLSIHLGKVLRISTSDLIVVCHIPV*FSCLQG 184
           +L I L + L+  TS  +++ H+P+   CLQG
Sbjct: 476 NLCIKLSEKLQSKTSSKVIIAHLPLLICCLQG 507


  Database: human
    Posted date:  Oct 23, 2007  1:18 PM
  Number of letters in database: 76,859,062
  Number of sequences in database:  237,096
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 80,228,790
Number of Sequences: 237096
Number of extensions: 1765918
Number of successful extensions: 3367
Number of sequences better than 10.0: 21
Number of HSP's better than 10.0 without gapping: 3279
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3367
length of database: 76,859,062
effective HSP length: 85
effective length of database: 56,705,902
effective search space used: 4990119376
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

- SilkBase 1999-2023 -