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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= bmov10o13
         (596 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_P48611 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase...   182   8e-45
UniRef50_Q03393 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase...   181   1e-44
UniRef50_UPI0000585023 Cluster: PREDICTED: hypothetical protein;...   146   3e-34
UniRef50_Q1ZXI0 Cluster: 6-pyruvoyltetrahydropterin synthase; n=...   143   3e-33
UniRef50_Q60PJ1 Cluster: Putative uncharacterized protein CBG222...   140   2e-32
UniRef50_Q675S7 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase...   137   2e-31
UniRef50_Q1IPI9 Cluster: 6-pyruvoyl tetrahydropterin synthase; n...   126   3e-28
UniRef50_Q2PY17 Cluster: 6-pyruvoyl-tetrahydropterin synthase; n...   121   1e-26
UniRef50_Q0I727 Cluster: 6-pyruvoyl-tetrahydropterin synthase ho...   118   1e-25
UniRef50_Q26EI1 Cluster: 6-pyruvoyl-tetrahydropterin synthase; n...   116   3e-25
UniRef50_Q1IPJ0 Cluster: 6-pyruvoyl tetrahydropterin synthase; n...   116   3e-25
UniRef50_Q5KZY1 Cluster: 6-pyruvoyltetrahydropterin synthase; n=...   116   4e-25
UniRef50_Q028J7 Cluster: Putative uncharacterized protein; n=1; ...   115   7e-25
UniRef50_A3XR13 Cluster: 6-pyruvoyltetrahydropterin synthase; n=...   110   2e-23
UniRef50_Q8KEA7 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase...   108   1e-22
UniRef50_A1ZSU4 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase...    99   4e-20
UniRef50_Q6ARY1 Cluster: Related to 6-pyruvoyl tetrahydropterin ...    89   6e-17
UniRef50_Q9WXP5 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase...    69   6e-11
UniRef50_P80081 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase...    60   7e-10
UniRef50_Q1IHK8 Cluster: Putative uncharacterized protein; n=2; ...    64   3e-09
UniRef50_Q31FT9 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase...    62   7e-09
UniRef50_Q0BPQ0 Cluster: Queuosine biosynthesis protein queD; n=...    61   2e-08
UniRef50_Q0LLP6 Cluster: Putative uncharacterized protein; n=1; ...    60   4e-08
UniRef50_Q6MLN9 Cluster: 6-pyruvoyltetrahydropterin synthase; n=...    59   7e-08
UniRef50_Q8R7N5 Cluster: 6-pyruvoyl-tetrahydropterin synthase; n...    58   2e-07
UniRef50_Q2IJB0 Cluster: 6-pyruvoyl tetrahydropterin synthase; n...    58   2e-07
UniRef50_P65872 Cluster: Putative 6-pyruvoyl tetrahydrobiopterin...    57   4e-07
UniRef50_Q98AM2 Cluster: Mll8751 protein; n=5; Proteobacteria|Re...    55   1e-06
UniRef50_Q81TC6 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase...    54   3e-06
UniRef50_Q8TS49 Cluster: 6-pyruvoyltetrahydropterin synthase; n=...    53   4e-06
UniRef50_Q89SC1 Cluster: Bll2482 protein; n=6; Bradyrhizobiaceae...    53   6e-06
UniRef50_A0PNB2 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase...    52   1e-05
UniRef50_A0LE55 Cluster: Putative uncharacterized protein; n=3; ...    52   1e-05
UniRef50_A6EFM8 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase...    52   1e-05
UniRef50_Q469A8 Cluster: 6-pyruvoyltetrahydropterin synthase; n=...    52   1e-05
UniRef50_Q1GPS3 Cluster: Putative uncharacterized protein; n=4; ...    51   2e-05
UniRef50_A7HXX3 Cluster: 6-pyruvoyl tetrahydropterin synthase; n...    51   2e-05
UniRef50_Q2LVK6 Cluster: Queuosine biosynthesis protein; n=5; Pr...    50   5e-05
UniRef50_Q64Q92 Cluster: 6-pyruvoyl-tetrahydropterin synthase; n...    48   1e-04
UniRef50_Q6MLY9 Cluster: 6-pyruvoyltetrahydropterin synthase; n=...    48   2e-04
UniRef50_A6PRS0 Cluster: Putative uncharacterized protein; n=1; ...    46   5e-04
UniRef50_Q74CF4 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase...    45   0.001
UniRef50_A4J5C6 Cluster: Putative uncharacterized protein; n=2; ...    45   0.001
UniRef50_Q3ZW85 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase...    45   0.002
UniRef50_A1HNF1 Cluster: Putative uncharacterized protein; n=1; ...    45   0.002
UniRef50_Q89ZC4 Cluster: 6-pyruvoyl-tetrahydropterin synthase; n...    44   0.002
UniRef50_Q3J9J8 Cluster: 6-pyruvoyl tetrahydropterin synthase; n...    44   0.002
UniRef50_A5D2E2 Cluster: 6-pyruvoyl-tetrahydropterin synthase; n...    44   0.004
UniRef50_A4CIF9 Cluster: 6-pyruvoyl tetrahydropterin synthase; n...    43   0.005
UniRef50_P44123 Cluster: Putative 6-pyruvoyl tetrahydrobiopterin...    43   0.005
UniRef50_O29809 Cluster: Putative 6-pyruvoyl tetrahydrobiopterin...    43   0.005
UniRef50_Q82UG9 Cluster: 6-pyruvoyl tetrahydropterin synthase; n...    43   0.006
UniRef50_Q4LA59 Cluster: Similar to 6-pyruvoyl tetrahydropterin ...    43   0.006
UniRef50_Q9UYV0 Cluster: PtpS-like 6-pyruvoyl-tetrahydropterin s...    43   0.006
UniRef50_Q2IKV5 Cluster: 6-pyruvoyl tetrahydropterin synthase; n...    41   0.019
UniRef50_Q8TIF6 Cluster: 6-pyruvoyltetrahydropterin synthase; n=...    41   0.025
UniRef50_Q7UGM2 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase...    40   0.034
UniRef50_O31676 Cluster: YkvK protein; n=25; Bacillales|Rep: Ykv...    40   0.059
UniRef50_A6GHT7 Cluster: Putative uncharacterized protein; n=1; ...    39   0.078
UniRef50_O66626 Cluster: Putative 6-pyruvoyl tetrahydrobiopterin...    39   0.078
UniRef50_A1SFN0 Cluster: Putative uncharacterized protein; n=1; ...    38   0.14 
UniRef50_Q55798 Cluster: Putative 6-pyruvoyl tetrahydrobiopterin...    38   0.14 
UniRef50_Q1D8H8 Cluster: Putative uncharacterized protein; n=1; ...    38   0.18 
UniRef50_A6GQ16 Cluster: Putative 6-pyruvoyl tetrahydrobiopterin...    38   0.18 
UniRef50_Q1NNT9 Cluster: Putative uncharacterized protein; n=3; ...    38   0.24 
UniRef50_Q12DE9 Cluster: Putative uncharacterized protein; n=4; ...    37   0.31 
UniRef50_A3UD70 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase...    37   0.31 
UniRef50_A4EHB1 Cluster: 6-pyruvoyl tetrahydropterin synthase; n...    37   0.41 
UniRef50_UPI000038E306 Cluster: hypothetical protein Faci_030017...    36   0.96 
UniRef50_Q8KCI4 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase...    35   1.3  
UniRef50_Q7RP45 Cluster: Putative uncharacterized protein PY0161...    35   1.3  
UniRef50_Q4Y977 Cluster: 6-pyruvoyl tetrahydropterin synthase, p...    35   1.3  
UniRef50_A7BS03 Cluster: 6-pyruvoyl tetrahydropterin synthase; n...    35   1.7  
UniRef50_A1WW30 Cluster: Putative uncharacterized protein; n=1; ...    34   2.2  
UniRef50_Q98S03 Cluster: Putative uncharacterized protein orf305...    34   2.2  
UniRef50_Q4A0G7 Cluster: Putative 6-pyruvoyl tetrahydrobiopterin...    34   2.9  
UniRef50_O27296 Cluster: Putative 6-pyruvoyl tetrahydrobiopterin...    34   2.9  
UniRef50_Q890G9 Cluster: Putative uncharacterized protein lp_005...    33   3.9  
UniRef50_Q7NSB8 Cluster: Probable 6-pyruvoyltetrahydrobiopterin ...    33   3.9  
UniRef50_Q0RM63 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase...    33   3.9  
UniRef50_Q97UC3 Cluster: Putative uncharacterized protein; n=1; ...    33   3.9  
UniRef50_Q8YJI9 Cluster: VACUOLAR ATP SYNTHASE 16 KD PROTEOLIPID...    33   5.1  
UniRef50_Q8FYB2 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase...    33   5.1  
UniRef50_Q8IIK5 Cluster: Putative uncharacterized protein; n=4; ...    33   5.1  
UniRef50_A3ZTI8 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase...    33   6.7  
UniRef50_A1KA79 Cluster: 6-pyruvoyltetrahydropterin synthase; n=...    33   6.7  
UniRef50_Q190Y3 Cluster: Cytochrome C family protein precursor; ...    32   8.9  
UniRef50_Q9HHN6 Cluster: Vng6306c; n=2; Halobacteriaceae|Rep: Vn...    32   8.9  

>UniRef50_P48611 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase;
           n=5; Endopterygota|Rep: 6-pyruvoyl tetrahydrobiopterin
           synthase - Drosophila melanogaster (Fruit fly)
          Length = 168

 Score =  182 bits (442), Expect = 8e-45
 Identities = 80/133 (60%), Positives = 105/133 (78%)
 Frame = +1

Query: 136 MSSLPIVSIIRRETFSSAHRLHSPFLSDEENKKVYGKCNNPNGHGHNYVVLVTVKGPVDP 315
           MS  P+  + RRETFS+ HRLHSP LSD EN +V+GKCNN +GHGHNY V +TV+GP+D 
Sbjct: 1   MSQQPVAFLTRRETFSACHRLHSPQLSDAENLEVFGKCNNFHGHGHNYTVEITVRGPIDR 60

Query: 316 QTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTENVAIYVWDQLQRIMEKP 495
           +TGMV+NIT+LK+ I+T I++ LDHKNLD DV YF    STTEN+A+Y+WD ++  ++KP
Sbjct: 61  RTGMVLNITELKEAIETVIMKRLDHKNLDKDVEYFANTPSTTENLAVYIWDNIRLQLKKP 120

Query: 496 QLLHEVKILEN*K 534
           +LL+EVKI E  K
Sbjct: 121 ELLYEVKIHETPK 133


>UniRef50_Q03393 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase;
           n=35; Eumetazoa|Rep: 6-pyruvoyl tetrahydrobiopterin
           synthase - Homo sapiens (Human)
          Length = 145

 Score =  181 bits (440), Expect = 1e-44
 Identities = 78/122 (63%), Positives = 102/122 (83%)
 Frame = +1

Query: 160 IIRRETFSSAHRLHSPFLSDEENKKVYGKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNI 339
           + RR +FS++HRL+S FLSDEEN K++GKCNNPNGHGHNY V+VTV G +DP TGMVMN+
Sbjct: 14  VSRRISFSASHRLYSKFLSDEENLKLFGKCNNPNGHGHNYKVVVTVHGEIDPATGMVMNL 73

Query: 340 TDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTENVAIYVWDQLQRIMEKPQLLHEVKI 519
            DLKKY++ AI++PLDHKNLD DVPYF  + STTENVA+Y+WD LQ+++    +L++VK+
Sbjct: 74  ADLKKYMEEAIMQPLDHKNLDMDVPYFADVVSTTENVAVYIWDNLQKVL-PVGVLYKVKV 132

Query: 520 LE 525
            E
Sbjct: 133 YE 134


>UniRef50_UPI0000585023 Cluster: PREDICTED: hypothetical protein;
           n=2; Strongylocentrotus purpuratus|Rep: PREDICTED:
           hypothetical protein - Strongylocentrotus purpuratus
          Length = 149

 Score =  146 bits (354), Expect = 3e-34
 Identities = 64/110 (58%), Positives = 83/110 (75%)
 Frame = +1

Query: 205 PFLSDEENKKVYGKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPL 384
           P L+D+EN K+Y KCNNPNGHGHNY V +T++G V P TGMVMNI+DLK Y+K   L+ L
Sbjct: 32  PELTDDENIKLYDKCNNPNGHGHNYKVELTLRGKVYPVTGMVMNISDLKTYMKNGFLDLL 91

Query: 385 DHKNLDNDVPYFKTMASTTENVAIYVWDQLQRIMEKPQLLHEVKILEN*K 534
           DHKNLD DV YF++  ST EN+AI++WD++ + +  P LL EVK+ E  K
Sbjct: 92  DHKNLDKDVNYFRSNVSTVENIAIFIWDRMAKCLPDPSLLFEVKVHETDK 141


>UniRef50_Q1ZXI0 Cluster: 6-pyruvoyltetrahydropterin synthase; n=1;
           Dictyostelium discoideum AX4|Rep:
           6-pyruvoyltetrahydropterin synthase - Dictyostelium
           discoideum AX4
          Length = 135

 Score =  143 bits (346), Expect = 3e-33
 Identities = 69/124 (55%), Positives = 92/124 (74%)
 Frame = +1

Query: 154 VSIIRRETFSSAHRLHSPFLSDEENKKVYGKCNNPNGHGHNYVVLVTVKGPVDPQTGMVM 333
           V + RRE FSS+HRL+S  LS EENKK+YGKC N   HGHNYV+ V++KG V    GM M
Sbjct: 5   VILTRREVFSSSHRLYSDKLSLEENKKIYGKCIN--SHGHNYVLEVSIKGAVKEDIGMFM 62

Query: 334 NITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTENVAIYVWDQLQRIMEKPQLLHEV 513
           NIT+LK+ +K  +++ LDHKNL+NDVP  K + +TTEN++I++WDQL   ++    L+EV
Sbjct: 63  NITELKEILKEKVMDKLDHKNLENDVPELKGIVTTTENLSIFIWDQLFPSLK--DFLYEV 120

Query: 514 KILE 525
           KILE
Sbjct: 121 KILE 124


>UniRef50_Q60PJ1 Cluster: Putative uncharacterized protein CBG22232;
           n=1; Caenorhabditis briggsae|Rep: Putative
           uncharacterized protein CBG22232 - Caenorhabditis
           briggsae
          Length = 137

 Score =  140 bits (339), Expect = 2e-32
 Identities = 66/130 (50%), Positives = 93/130 (71%)
 Frame = +1

Query: 145 LPIVSIIRRETFSSAHRLHSPFLSDEENKKVYGKCNNPNGHGHNYVVLVTVKGPVDPQTG 324
           +P V++ R E FS+AHRL+S  LS  ENK+ +GKCNN NGHGHNYV  V ++G VDP +G
Sbjct: 1   MPTVTMERVEMFSAAHRLNSENLSVAENKETFGKCNNDNGHGHNYVWKVKLRGEVDPVSG 60

Query: 325 MVMNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTENVAIYVWDQLQRIMEKPQLL 504
           MV ++  LKK +   +L+ +DH+NLD DV +FKT  ST+ENVAIY++ +L+ +M  P +L
Sbjct: 61  MVYDLAKLKKEM-NLVLDTVDHRNLDKDVEFFKTTVSTSENVAIYMYQKLKSVMSNPSVL 119

Query: 505 HEVKILEN*K 534
           ++  I E  K
Sbjct: 120 YKCTIEETPK 129


>UniRef50_Q675S7 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase;
           n=1; Oikopleura dioica|Rep: 6-pyruvoyl
           tetrahydrobiopterin synthase - Oikopleura dioica
           (Tunicate)
          Length = 136

 Score =  137 bits (331), Expect = 2e-31
 Identities = 60/108 (55%), Positives = 79/108 (73%)
 Frame = +1

Query: 157 SIIRRETFSSAHRLHSPFLSDEENKKVYGKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMN 336
           SIIR E   + HRLHSP+L+DEEN+KVYGKCN+PNGHGHNY +   ++G +  +TGMVMN
Sbjct: 4   SIIRTEKICTGHRLHSPYLTDEENRKVYGKCNHPNGHGHNYTIQAVIEGEIIKETGMVMN 63

Query: 337 ITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTENVAIYVWDQLQR 480
           + DL K     +L  LDH+N+D DV YFK + ST ENVA +++ QL +
Sbjct: 64  LVDL-KVAMWKVLSQLDHRNVDKDVEYFKNVPSTAENVAQWIFIQLSQ 110


>UniRef50_Q1IPI9 Cluster: 6-pyruvoyl tetrahydropterin synthase; n=2;
           Acidobacteria|Rep: 6-pyruvoyl tetrahydropterin synthase
           - Acidobacteria bacterium (strain Ellin345)
          Length = 137

 Score =  126 bits (305), Expect = 3e-28
 Identities = 54/125 (43%), Positives = 86/125 (68%)
 Frame = +1

Query: 151 IVSIIRRETFSSAHRLHSPFLSDEENKKVYGKCNNPNGHGHNYVVLVTVKGPVDPQTGMV 330
           +V + R+  FS++H  H+P  + EEN +V+GKCNN NGHGHNY + VTVKG VD  TG V
Sbjct: 2   VVYLTRKSEFSASHHYHNPDFTAEENLRVFGKCNNSNGHGHNYTLEVTVKGTVDATTGFV 61

Query: 331 MNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTENVAIYVWDQLQRIMEKPQLLHE 510
           +++  LK+ +   +++ +DH+ L+++VP FK+   TTEN+AI +W +L+  +   + LH 
Sbjct: 62  VDLKQLKEIMNREVVDAMDHRYLNHEVPEFKSQIPTTENIAIAIWKRLEGKLHVAK-LHR 120

Query: 511 VKILE 525
           V++ E
Sbjct: 121 VRLYE 125


>UniRef50_Q2PY17 Cluster: 6-pyruvoyl-tetrahydropterin synthase; n=2;
           Bacteria|Rep: 6-pyruvoyl-tetrahydropterin synthase -
           uncultured marine bacterium Ant39E11
          Length = 137

 Score =  121 bits (291), Expect = 1e-26
 Identities = 55/126 (43%), Positives = 87/126 (69%), Gaps = 1/126 (0%)
 Frame = +1

Query: 151 IVSIIRRETFSSAHRLHSPFLSDEENKKVYGKCNNPNGHGHNYVVLVTVKGPVDPQTGMV 330
           ++ I RR  FS+AHRL +P  SDE+N+ V+G C N   HGHN+ ++VTVKG V+  TG V
Sbjct: 1   MIYIQRRAIFSAAHRLANPSWSDEKNQAVFGHCANEYSHGHNFQLIVTVKGEVNTDTGFV 60

Query: 331 MNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTENVAIYVWDQLQ-RIMEKPQLLH 507
           MN+ DLK  + + I++ +DH+NL++DVP+ + +  +TEN+A+  W Q++  I +    LH
Sbjct: 61  MNMVDLKAIMDSEIIQHVDHRNLNHDVPFMQGIMPSTENLAMIFWQQIEGPIAKHGAALH 120

Query: 508 EVKILE 525
            ++I+E
Sbjct: 121 CIRIVE 126


>UniRef50_Q0I727 Cluster: 6-pyruvoyl-tetrahydropterin synthase
           homolog; n=35; Cyanobacteria|Rep:
           6-pyruvoyl-tetrahydropterin synthase homolog -
           Synechococcus sp. (strain CC9311)
          Length = 306

 Score =  118 bits (284), Expect = 1e-25
 Identities = 53/121 (43%), Positives = 81/121 (66%), Gaps = 1/121 (0%)
 Frame = +1

Query: 169 RETFSSAHRLHSPFLSDEENKKVYGKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDL 348
           R  F++AHRL  P LS EEN+ +YGKC  P+GHGHNY+V VTV+G +DP+TGMV ++  L
Sbjct: 159 RTHFAAAHRLARPELSQEENELIYGKCARPHGHGHNYLVDVTVRGSIDPRTGMVCDLAAL 218

Query: 349 KKYIKTAILEPLDHKNLDNDVPYFKTMASTTENVAIYVWDQLQR-IMEKPQLLHEVKILE 525
           ++ +   ++EP DH  L+ DV +F     T EN+A+++ D+L   +      LH+V++ E
Sbjct: 219 QRLVSDLVVEPFDHTFLNKDVAHFADCVPTAENIALHIVDRLTTPVRAIGAQLHKVRLQE 278

Query: 526 N 528
           +
Sbjct: 279 S 279



 Score = 77.0 bits (181), Expect = 3e-13
 Identities = 41/110 (37%), Positives = 64/110 (58%), Gaps = 5/110 (4%)
 Frame = +1

Query: 160 IIRRETFSSAHRLHSPFLSDEENKKVYGKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNI 339
           I RR  FSS+HR   P LS ++N   +G C    GHGHNY ++V++ G +D   GMV+N+
Sbjct: 18  ITRRACFSSSHRYWLPELSADDNAARFGSCAMAPGHGHNYELIVSMAGGLD-ANGMVLNL 76

Query: 340 TDLKKYIKTAILEPLDHKNLDNDVPYFKTMAS-----TTENVAIYVWDQL 474
           +++K  I++ + E LD + L+   P F   +S     TTE +   +W +L
Sbjct: 77  SEVKHAIRSEVTEQLDFRFLNEAWPEFDVSSSEGCLPTTEALVRIIWSRL 126


>UniRef50_Q26EI1 Cluster: 6-pyruvoyl-tetrahydropterin synthase; n=5;
           Bacteroidetes|Rep: 6-pyruvoyl-tetrahydropterin synthase
           - Flavobacteria bacterium BBFL7
          Length = 136

 Score =  116 bits (280), Expect = 3e-25
 Identities = 52/125 (41%), Positives = 85/125 (68%)
 Frame = +1

Query: 151 IVSIIRRETFSSAHRLHSPFLSDEENKKVYGKCNNPNGHGHNYVVLVTVKGPVDPQTGMV 330
           I++  R+  F++AHRLH    SD++N  ++GKCNNPN HGHNY + V V G VDP+TG +
Sbjct: 2   IITAYRKAHFNAAHRLHRSDWSDQKNAAIFGKCNNPNFHGHNYNLEVGVTGKVDPETGYL 61

Query: 331 MNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTENVAIYVWDQLQRIMEKPQLLHE 510
           +++  LK  IK+ + +  DHKNL+ +VP FKT+  T EN+A  ++++++  ++    + E
Sbjct: 62  IDLKILKDVIKSEVEDAFDHKNLNVEVPEFKTLNPTAENIAYVIYNKIKAKLDSKYDI-E 120

Query: 511 VKILE 525
           +K+ E
Sbjct: 121 IKLYE 125


>UniRef50_Q1IPJ0 Cluster: 6-pyruvoyl tetrahydropterin synthase; n=1;
           Acidobacteria bacterium Ellin345|Rep: 6-pyruvoyl
           tetrahydropterin synthase - Acidobacteria bacterium
           (strain Ellin345)
          Length = 135

 Score =  116 bits (280), Expect = 3e-25
 Identities = 53/107 (49%), Positives = 76/107 (71%)
 Frame = +1

Query: 160 IIRRETFSSAHRLHSPFLSDEENKKVYGKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNI 339
           + RR  F ++HRLH+P LS+ EN++VYGKCNNP GHGHNY + VTV G V P TGMV N+
Sbjct: 5   LTRRYWFVASHRLHTPRLSEAENREVYGKCNNPFGHGHNYALEVTVGGQVAPDTGMVYNL 64

Query: 340 TDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTENVAIYVWDQLQR 480
            D+ + ++  ILE  DH+NL N +  F+ +  TTEN+ + +++ L+R
Sbjct: 65  ADVDRVVRKHILERYDHQNL-NCLKEFQELVPTTENLCLAIFEILKR 110


>UniRef50_Q5KZY1 Cluster: 6-pyruvoyltetrahydropterin synthase; n=6;
           Bacteria|Rep: 6-pyruvoyltetrahydropterin synthase -
           Geobacillus kaustophilus
          Length = 134

 Score =  116 bits (279), Expect = 4e-25
 Identities = 52/103 (50%), Positives = 71/103 (68%)
 Frame = +1

Query: 166 RRETFSSAHRLHSPFLSDEENKKVYGKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITD 345
           RR  FSSAHRLHS  L++EEN++++GKCNN  GHGHNY + VTV G  DP TGMV+N+ +
Sbjct: 3   RRYYFSSAHRLHSDQLTNEENQRLFGKCNNRYGHGHNYCLEVTVIGKPDPITGMVVNLAE 62

Query: 346 LKKYIKTAILEPLDHKNLDNDVPYFKTMASTTENVAIYVWDQL 474
           L + +   +L   DHK+L+ D   FK +  T EN+ I +W+ L
Sbjct: 63  LDEIVNREVLVKFDHKHLNLDTDEFKQINPTAENIVIVIWELL 105


>UniRef50_Q028J7 Cluster: Putative uncharacterized protein; n=1;
           Solibacter usitatus Ellin6076|Rep: Putative
           uncharacterized protein - Solibacter usitatus (strain
           Ellin6076)
          Length = 141

 Score =  115 bits (277), Expect = 7e-25
 Identities = 50/105 (47%), Positives = 74/105 (70%)
 Frame = +1

Query: 166 RRETFSSAHRLHSPFLSDEENKKVYGKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITD 345
           RR  F+++HRLHS  LS EEN+ +YGKCNNP GHGHNYVV V+V+GPVD  TG  ++I  
Sbjct: 3   RRYQFAASHRLHSDQLSAEENRSLYGKCNNPYGHGHNYVVEVSVRGPVDEATGRTVDIVL 62

Query: 346 LKKYIKTAILEPLDHKNLDNDVPYFKTMASTTENVAIYVWDQLQR 480
           L + ++  +++P DH+NL+ +V  F    +T+EN+   +  +L+R
Sbjct: 63  LDELVRREVVQPFDHRNLNAEVDAFTKAVATSENLGFEICRRLKR 107


>UniRef50_A3XR13 Cluster: 6-pyruvoyltetrahydropterin synthase; n=13;
           Bacteroidetes|Rep: 6-pyruvoyltetrahydropterin synthase -
           Leeuwenhoekiella blandensis MED217
          Length = 137

 Score =  110 bits (265), Expect = 2e-23
 Identities = 51/129 (39%), Positives = 83/129 (64%)
 Frame = +1

Query: 154 VSIIRRETFSSAHRLHSPFLSDEENKKVYGKCNNPNGHGHNYVVLVTVKGPVDPQTGMVM 333
           V++ R+  F++AHRL+     D +N +V+GKC+ PN HGHNY ++V V G +DP+TG V+
Sbjct: 4   VTVKRKAHFNAAHRLYRADWDDAKNLEVFGKCSYPNYHGHNYELIVAVTGEIDPKTGFVI 63

Query: 334 NITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTENVAIYVWDQLQRIMEKPQLLHEV 513
           ++  LK  IK+ + EP DHKNL+ DV  F  +  T EN+ + ++D+L+  ++  +   EV
Sbjct: 64  DLKVLKDLIKSEVEEPFDHKNLNLDVAEFSQLNPTAENICVVIYDRLKAKLD-AKFAIEV 122

Query: 514 KILEN*KKS 540
            + E  + S
Sbjct: 123 TLYETPRNS 131


>UniRef50_Q8KEA7 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase,
           putative; n=10; Chlorobiaceae|Rep: 6-pyruvoyl
           tetrahydrobiopterin synthase, putative - Chlorobium
           tepidum
          Length = 149

 Score =  108 bits (259), Expect = 1e-22
 Identities = 52/133 (39%), Positives = 87/133 (65%), Gaps = 4/133 (3%)
 Frame = +1

Query: 154 VSIIRRETFSSAHRLHSPFLSDEENKKVYGKCNNPNGHGHNYVVLVTVKGPVDPQTGMVM 333
           + + R+  F++AHRL +P LSDEEN+++YGKC+   GHGHNY++ +T+ G +D +TG + 
Sbjct: 11  IYVTRQIEFNAAHRLFNPELSDEENQQLYGKCSGKYGHGHNYLLEITLSGIIDRKTGYLF 70

Query: 334 NITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTENVAIYVWD----QLQRIMEKPQL 501
           ++ +LKK ++  I+   DH++L+++V        TTE +A+ VW+    +L+ I ++   
Sbjct: 71  DLKELKKILEEEIVARFDHRHLNHEVNELAGHVPTTEILAVIVWEILDSRLKTITKQEVS 130

Query: 502 LHEVKILEN*KKS 540
           LHEV I E  K S
Sbjct: 131 LHEVIIHETGKNS 143


>UniRef50_A1ZSU4 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase;
           n=3; Flexibacteraceae|Rep: 6-pyruvoyl
           tetrahydrobiopterin synthase - Microscilla marina ATCC
           23134
          Length = 158

 Score =   99 bits (238), Expect = 4e-20
 Identities = 50/128 (39%), Positives = 82/128 (64%), Gaps = 3/128 (2%)
 Frame = +1

Query: 151 IVSIIRRETFSSAHRLHSPFLSDEENKKVYGKCNNPNGHGHNYVVLVTVKGPVDPQTGMV 330
           +V I RRETF+++H+L++P  S E+N+ ++G C N N HGHN+ ++VTVKG  D +TGMV
Sbjct: 1   MVYICRRETFNASHKLYNPNWSKEQNEALFGVCANQNWHGHNFELVVTVKGMPDLETGMV 60

Query: 331 MNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTENVAIYVWDQLQRIM--EKPQ-L 501
           ++   L K ++  I+E + +KNL+ DV +      + E + I  W +L   +  E P+  
Sbjct: 61  IDYKVLSKIVRREIIEKVHYKNLNLDVDFLAGKMPSCEILIIEFWKRLAPAIQQESPRTT 120

Query: 502 LHEVKILE 525
           LH +K++E
Sbjct: 121 LHHLKLVE 128


>UniRef50_Q6ARY1 Cluster: Related to 6-pyruvoyl tetrahydropterin
           synthase; n=1; Desulfotalea psychrophila|Rep: Related to
           6-pyruvoyl tetrahydropterin synthase - Desulfotalea
           psychrophila
          Length = 136

 Score = 89.4 bits (212), Expect = 6e-17
 Identities = 43/128 (33%), Positives = 82/128 (64%), Gaps = 1/128 (0%)
 Frame = +1

Query: 145 LPIVSIIRRETFSSAHRLHSPFLSDEENKKVYGKCNNPNGHGHNYVVLVTVKGPVDPQTG 324
           + +++I +   F +AH+L    L+D+EN++ +GKC+    HGH Y + +T+ G V P  G
Sbjct: 1   MAMLTITKEFRFDAAHKLFLKDLTDQENREAFGKCSQL--HGHTYCLRITITGKVQP-NG 57

Query: 325 MVMNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTENVAIYVWDQLQRIMEKPQL- 501
           MV+N TDLK+ ++  I+   DH +L N++  ++ + +T EN+++Y++  L   ++K ++ 
Sbjct: 58  MVLNFTDLKQIVEEKIIARYDHSHL-NELEEYRDLPTTAENMSLYIFKVLAACLKKQKVT 116

Query: 502 LHEVKILE 525
           L EV++ E
Sbjct: 117 LTEVQLYE 124


>UniRef50_Q9WXP5 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase,
           putative; n=9; Bacteria|Rep: 6-pyruvoyl
           tetrahydrobiopterin synthase, putative - Thermotoga
           maritima
          Length = 120

 Score = 69.3 bits (162), Expect = 6e-11
 Identities = 40/96 (41%), Positives = 61/96 (63%), Gaps = 1/96 (1%)
 Frame = +1

Query: 241 GKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYF 420
           GKC     HGH Y ++V ++GP++ +  MVM+  +LKK ++  ++  LDH  L ND+  F
Sbjct: 20  GKCERL--HGHTYRLVVKIEGPLNEEE-MVMDFAELKKIVEELVISKLDHSYL-NDM--F 73

Query: 421 KTMASTTENVAIYVWDQLQRIMEKPQL-LHEVKILE 525
                TTE VAI++WDQL + MEK  + LHE+++ E
Sbjct: 74  DQ--PTTERVAIWIWDQLSKEMEKRGVRLHEIELWE 107


>UniRef50_P80081 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase;
           n=1; Salmo salar|Rep: 6-pyruvoyl tetrahydrobiopterin
           synthase - Salmo salar (Atlantic salmon)
          Length = 103

 Score = 60.5 bits (140), Expect(2) = 7e-10
 Identities = 34/70 (48%), Positives = 47/70 (67%)
 Frame = +1

Query: 325 MVMNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTENVAIYVWDQLQRIMEKPQLL 504
           +VMNIT++K++I+  I  PLDHKNLD DVPYF  +     NVA+Y+ D + + +    LL
Sbjct: 34  LVMNITNIKEHIEEVI--PLDHKNLDKDVPYFANV-----NVAVYIXDNMVKQL-PANLL 85

Query: 505 HEVKILEN*K 534
           +EVKI E  K
Sbjct: 86  YEVKIHETDK 95



 Score = 25.4 bits (53), Expect(2) = 7e-10
 Identities = 10/18 (55%), Positives = 14/18 (77%)
 Frame = +1

Query: 160 IIRRETFSSAHRLHSPFL 213
           I R ++F ++HRLHSP L
Sbjct: 17  ITRVQSFCASHRLHSPTL 34


>UniRef50_Q1IHK8 Cluster: Putative uncharacterized protein; n=2;
           Acidobacteria|Rep: Putative uncharacterized protein -
           Acidobacteria bacterium (strain Ellin345)
          Length = 125

 Score = 63.7 bits (148), Expect = 3e-09
 Identities = 31/82 (37%), Positives = 51/82 (62%)
 Frame = +1

Query: 241 GKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYF 420
           GKC NP  HGHNY V VT++G      G++++  DLK  +K  +++ LDH+ + ND+P F
Sbjct: 21  GKCENP--HGHNYKVRVTLQGRELDHAGLLLDFKDLKVVMK-PVVDYLDHQMM-NDIPPF 76

Query: 421 KTMASTTENVAIYVWDQLQRIM 486
             +  + EN+A Y +D+  + +
Sbjct: 77  NEVNPSAENIARYFYDECNKFL 98


>UniRef50_Q31FT9 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase;
           n=3; Gammaproteobacteria|Rep: 6-pyruvoyl
           tetrahydrobiopterin synthase - Thiomicrospira crunogena
           (strain XCL-2)
          Length = 125

 Score = 62.5 bits (145), Expect = 7e-09
 Identities = 35/96 (36%), Positives = 55/96 (57%), Gaps = 1/96 (1%)
 Frame = +1

Query: 265 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTE 444
           HGHN+ + V V G      GM+++  ++K++ K  I E LDH  L ND P+FK    T E
Sbjct: 30  HGHNWKIEVQVVGDKLNDIGMLVDFKEIKRHAKEVISE-LDHTFL-NDHPHFKEKNPTAE 87

Query: 445 NVAIYVWDQL-QRIMEKPQLLHEVKILEN*KKSCCV 549
           N+A Y++ Q+ QRI      +H + + EN  ++C +
Sbjct: 88  NIAEYIYKQIQQRIQSSTVKMHSLTVWEN-DRNCVI 122


>UniRef50_Q0BPQ0 Cluster: Queuosine biosynthesis protein queD; n=1;
           Granulibacter bethesdensis CGDNIH1|Rep: Queuosine
           biosynthesis protein queD - Granulobacter bethesdensis
           (strain ATCC BAA-1260 / CGDNIH1)
          Length = 130

 Score = 60.9 bits (141), Expect = 2e-08
 Identities = 39/113 (34%), Positives = 66/113 (58%), Gaps = 1/113 (0%)
 Frame = +1

Query: 139 SSLP-IVSIIRRETFSSAHRLHSPFLSDEENKKVYGKCNNPNGHGHNYVVLVTVKGPVDP 315
           SS+P ++ I ++ TF +AH LH    +D   +           HGH+Y V V ++G VDP
Sbjct: 6   SSMPRVLEIGKQFTFEAAHTLHREIETDSSLRI----------HGHSYRVEVVLRGGVDP 55

Query: 316 QTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTENVAIYVWDQL 474
            +GM+M++  L++ +  A+ + LDH+ LD +VP      +T EN+A+++W  L
Sbjct: 56  DSGMLMDLGLLQRKM-NAVRDALDHRLLD-EVP--GLAPATMENIALFIWRHL 104


>UniRef50_Q0LLP6 Cluster: Putative uncharacterized protein; n=1;
           Herpetosiphon aurantiacus ATCC 23779|Rep: Putative
           uncharacterized protein - Herpetosiphon aurantiacus ATCC
           23779
          Length = 133

 Score = 60.1 bits (139), Expect = 4e-08
 Identities = 37/101 (36%), Positives = 60/101 (59%), Gaps = 6/101 (5%)
 Frame = +1

Query: 241 GKCNNPNGHGHNYVVLVTVKGPVDP-----QTGMVMNITDLKKYIKTAILEPLDHKNLDN 405
           GKC     HGH+Y++ V+V+G + P       GMV+++  +K+ +   I+  +DH NL N
Sbjct: 22  GKCARL--HGHSYLLEVSVRGLIQPTRGQSDDGMVIDLEQIKQLVNEIIIARVDHYNL-N 78

Query: 406 DVPYFKTMASTTENVAIYVWDQL-QRIMEKPQLLHEVKILE 525
           D   F ++ ST EN+A ++WDQL Q+  E   LL  +++ E
Sbjct: 79  D---FLSVPSTAENIAHWMWDQLEQQAPEFAALLWRIRLWE 116


>UniRef50_Q6MLN9 Cluster: 6-pyruvoyltetrahydropterin synthase; n=1;
           Bdellovibrio bacteriovorus|Rep:
           6-pyruvoyltetrahydropterin synthase - Bdellovibrio
           bacteriovorus
          Length = 129

 Score = 59.3 bits (137), Expect = 7e-08
 Identities = 32/114 (28%), Positives = 59/114 (51%)
 Frame = +1

Query: 160 IIRRETFSSAHRLHSPFLSDEENKKVYGKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNI 339
           I  +  FS+AH    P   + +N++ +G+C    GHGHNY++        D       + 
Sbjct: 3   ITLKSPFSAAHFYAQPQWDEHKNRETFGRCYTQYGHGHNYMLEAGFHCQNDSWKQQQQHY 62

Query: 340 TDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTENVAIYVWDQLQRIMEKPQL 501
             +   + TA+   LDH++L+  +P FKT   TTEN+ +Y  ++L+  ++  ++
Sbjct: 63  QSVLNNL-TAV---LDHEHLNFVIPEFKTNIPTTENICLYFLEKLKSQVKSEEI 112


>UniRef50_Q8R7N5 Cluster: 6-pyruvoyl-tetrahydropterin synthase; n=3;
           Clostridia|Rep: 6-pyruvoyl-tetrahydropterin synthase -
           Thermoanaerobacter tengcongensis
          Length = 122

 Score = 57.6 bits (133), Expect = 2e-07
 Identities = 33/86 (38%), Positives = 52/86 (60%)
 Frame = +1

Query: 238 YGKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPY 417
           +GKC     HGH Y + VTV+G  D + GMV++   LK+ +   I++ LDHK L N+V  
Sbjct: 19  HGKCEEL--HGHTYRLEVTVEGYPDEE-GMVLDFVKLKEIVNEKIIKKLDHKYL-NEVLG 74

Query: 418 FKTMASTTENVAIYVWDQLQRIMEKP 495
           F T   T EN+ +++W +L+  ++ P
Sbjct: 75  FNT---TCENILLWMWKELEGELKGP 97


>UniRef50_Q2IJB0 Cluster: 6-pyruvoyl tetrahydropterin synthase; n=2;
           Anaeromyxobacter|Rep: 6-pyruvoyl tetrahydropterin
           synthase - Anaeromyxobacter dehalogenans (strain 2CP-C)
          Length = 129

 Score = 57.6 bits (133), Expect = 2e-07
 Identities = 28/71 (39%), Positives = 43/71 (60%)
 Frame = +1

Query: 265 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTE 444
           HGHNY   V ++G VDP TGM+ +  D+K+ +   +L  +DH+ L NDV        T E
Sbjct: 37  HGHNYRFFVALEGEVDPATGMIADFGDVKRIVAEHVLARVDHRTL-NDV----LDNPTAE 91

Query: 445 NVAIYVWDQLQ 477
           N+A ++W+ L+
Sbjct: 92  NIARWMWEVLE 102


>UniRef50_P65872 Cluster: Putative 6-pyruvoyl tetrahydrobiopterin
           synthase; n=24; Proteobacteria|Rep: Putative 6-pyruvoyl
           tetrahydrobiopterin synthase - Shigella flexneri
          Length = 121

 Score = 56.8 bits (131), Expect = 4e-07
 Identities = 41/123 (33%), Positives = 64/123 (52%)
 Frame = +1

Query: 175 TFSSAHRLHSPFLSDEENKKVYGKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKK 354
           TF +AHRL  P + +        KC     HGH+++V + + G VDP TG +++  +LK 
Sbjct: 11  TFEAAHRL--PHVPEGH------KCGRL--HGHSFMVRLEITGEVDPHTGWIIDFAELKA 60

Query: 355 YIKTAILEPLDHKNLDNDVPYFKTMASTTENVAIYVWDQLQRIMEKPQLLHEVKILEN*K 534
             K    E LDH  L ND+P  +    T+E +A ++WDQ++ ++    LL  V + E   
Sbjct: 61  AFKPT-YERLDHHYL-NDIPGLEN--PTSEVLAKWIWDQVKPVV---PLLSAVMVKETCT 113

Query: 535 KSC 543
             C
Sbjct: 114 AGC 116


>UniRef50_Q98AM2 Cluster: Mll8751 protein; n=5; Proteobacteria|Rep:
           Mll8751 protein - Rhizobium loti (Mesorhizobium loti)
          Length = 117

 Score = 54.8 bits (126), Expect = 1e-06
 Identities = 26/74 (35%), Positives = 48/74 (64%)
 Frame = +1

Query: 265 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTE 444
           HGH+Y V + ++GPVDP TG V++  D++  +   +L+ LDH+ L N++        T E
Sbjct: 28  HGHSYRVELRLEGPVDPDTGFVIDFFDVEA-VFGPLLQRLDHQYL-NEIEGLDN--PTAE 83

Query: 445 NVAIYVWDQLQRIM 486
           N+A+++W+Q + ++
Sbjct: 84  NIAVWIWNQTKPLL 97


>UniRef50_Q81TC6 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase,
           putative; n=18; Bacilli|Rep: 6-pyruvoyl
           tetrahydrobiopterin synthase, putative - Bacillus
           anthracis
          Length = 163

 Score = 54.0 bits (124), Expect = 3e-06
 Identities = 35/121 (28%), Positives = 61/121 (50%)
 Frame = +1

Query: 154 VSIIRRETFSSAHRLHSPFLSDEENKKVYGKCNNPNGHGHNYVVLVTVKGPVDPQTGMVM 333
           V + +  TF +AH LH             GKC N   HGH Y V+  + G V+ + G+ +
Sbjct: 32  VMVSKEFTFDAAHHLHC----------YEGKCKNL--HGHTYKVVFGISGYVN-EIGLAI 78

Query: 334 NITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTENVAIYVWDQLQRIMEKPQLLHEV 513
           +  D+K+  K  I   LDH+ L+  +P    M +T EN+ +++++++   + K    +E 
Sbjct: 79  DFGDIKEIWKNEIEIYLDHRYLNETLP---AMNTTAENMVVWIYEKMAEALTKDNRANEY 135

Query: 514 K 516
           K
Sbjct: 136 K 136


>UniRef50_Q8TS49 Cluster: 6-pyruvoyltetrahydropterin synthase; n=3;
           cellular organisms|Rep: 6-pyruvoyltetrahydropterin
           synthase - Methanosarcina acetivorans
          Length = 123

 Score = 53.2 bits (122), Expect = 4e-06
 Identities = 31/99 (31%), Positives = 57/99 (57%), Gaps = 1/99 (1%)
 Frame = +1

Query: 208 FLSDEENKKVYGKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLD 387
           F +  + K V  KC N   HGHN+ + V V G      G++M+  +LK+ + + I + LD
Sbjct: 10  FAAAHQLKMVAKKCENL--HGHNWKIEVCVAGEKLNDAGIMMDFGELKQNV-SEITKTLD 66

Query: 388 HKNLDNDVPYFK-TMASTTENVAIYVWDQLQRIMEKPQL 501
           H N  N++ YF      ++EN+A+Y+ + L+ +++ P++
Sbjct: 67  H-NFLNELDYFDDNNPPSSENIAVYIANSLKAMLKDPEI 104


>UniRef50_Q89SC1 Cluster: Bll2482 protein; n=6;
           Bradyrhizobiaceae|Rep: Bll2482 protein - Bradyrhizobium
           japonicum
          Length = 121

 Score = 52.8 bits (121), Expect = 6e-06
 Identities = 30/73 (41%), Positives = 46/73 (63%)
 Frame = +1

Query: 265 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTE 444
           HGH++   VTV+G  DP+TGMV+++  L++ I+   L  LDHK L+      K    T E
Sbjct: 29  HGHSFRAEVTVRGTPDPETGMVVDLGLLQRAIEDVRL-TLDHKFLNKIEALGK---PTLE 84

Query: 445 NVAIYVWDQLQRI 483
           N++ +VW++LQ I
Sbjct: 85  NLSRFVWERLQHI 97


>UniRef50_A0PNB2 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase;
           n=2; Actinomycetales|Rep: 6-pyruvoyl tetrahydrobiopterin
           synthase - Mycobacterium ulcerans (strain Agy99)
          Length = 160

 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 37/123 (30%), Positives = 59/123 (47%)
 Frame = +1

Query: 175 TFSSAHRLHSPFLSDEENKKVYGKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKK 354
           TF SAHRL         N     KC     HGH+Y     V+GPVDP+ G +++   +K 
Sbjct: 12  TFESAHRL--------PNVPAGHKCGRL--HGHSYRARTYVEGPVDPRAGWIVDFGKIKD 61

Query: 355 YIKTAILEPLDHKNLDNDVPYFKTMASTTENVAIYVWDQLQRIMEKPQLLHEVKILEN*K 534
             K  I   LDH  L N++   +    T+E +++++W +L  ++  P ++  V + E   
Sbjct: 62  ACKPVIAR-LDHYYL-NEIDGLEN--PTSEQLSMWIWRELATLL--PMMMSAVSVSETCS 115

Query: 535 KSC 543
             C
Sbjct: 116 SGC 118


>UniRef50_A0LE55 Cluster: Putative uncharacterized protein; n=3;
           Deltaproteobacteria|Rep: Putative uncharacterized
           protein - Syntrophobacter fumaroxidans (strain DSM 10017
           / MPOB)
          Length = 127

 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 28/97 (28%), Positives = 58/97 (59%), Gaps = 1/97 (1%)
 Frame = +1

Query: 241 GKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYF 420
           GKC N   HGHN+ + + ++G    + G++++  ++K+  + A+L  +DH  L N++P+F
Sbjct: 25  GKCENL--HGHNWKIEIVLRGTELNEIGVLVDFGEVKQATR-ALLSEVDHHYL-NEIPFF 80

Query: 421 KTMASTTENVAIYVWDQLQRIMEKPQL-LHEVKILEN 528
                ++EN+A Y++++L    +  +L L+ V   E+
Sbjct: 81  ADRNPSSENIARYLFERLAEKFDNDKLRLYRVSAWES 117


>UniRef50_A6EFM8 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase,
           putative; n=1; Pedobacter sp. BAL39|Rep: 6-pyruvoyl
           tetrahydrobiopterin synthase, putative - Pedobacter sp.
           BAL39
          Length = 117

 Score = 51.6 bits (118), Expect = 1e-05
 Identities = 25/73 (34%), Positives = 46/73 (63%)
 Frame = +1

Query: 265 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTE 444
           HGH Y + V + G  DP +G V +  DLK+ I+   ++ LDH+ L ND+P  +    T+E
Sbjct: 28  HGHTYQLTVYLSGTPDPHSGWVADFGDLKRGIQ-PFVDLLDHRLL-NDIPGLEN--PTSE 83

Query: 445 NVAIYVWDQLQRI 483
           N+++++W +++ +
Sbjct: 84  NLSVWLWQKIKPV 96


>UniRef50_Q469A8 Cluster: 6-pyruvoyltetrahydropterin synthase; n=1;
           Methanosarcina barkeri str. Fusaro|Rep:
           6-pyruvoyltetrahydropterin synthase - Methanosarcina
           barkeri (strain Fusaro / DSM 804)
          Length = 112

 Score = 51.6 bits (118), Expect = 1e-05
 Identities = 32/99 (32%), Positives = 57/99 (57%), Gaps = 1/99 (1%)
 Frame = +1

Query: 208 FLSDEENKKVYGKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLD 387
           F +  + K V  KC N   HGHN+ V V V G    + G++++  +LK+ + + I+  LD
Sbjct: 10  FAAAHQLKMVAKKCENL--HGHNWKVEVCVAGEKLNEAGVLVDFGELKQKV-SEIVTRLD 66

Query: 388 HKNLDNDVPYFK-TMASTTENVAIYVWDQLQRIMEKPQL 501
           H N  N++ YF  +   ++EN+A Y+   LQ +++ P++
Sbjct: 67  H-NFLNELEYFNDSNPPSSENIAQYIATSLQTMLKDPEI 104


>UniRef50_Q1GPS3 Cluster: Putative uncharacterized protein; n=4;
           Proteobacteria|Rep: Putative uncharacterized protein -
           Sphingopyxis alaskensis (Sphingomonas alaskensis)
          Length = 124

 Score = 50.8 bits (116), Expect = 2e-05
 Identities = 31/99 (31%), Positives = 56/99 (56%), Gaps = 2/99 (2%)
 Frame = +1

Query: 265 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLD--NDVPYFKTMAST 438
           HGH+Y   VTV+G  DP TGM++++  L++ ++ A  + LDH+ LD  ND+       +T
Sbjct: 29  HGHSYRAEVTVRGRPDPATGMIVDLGLLERSMEDA-RDALDHRFLDEINDLG-----PAT 82

Query: 439 TENVAIYVWDQLQRIMEKPQLLHEVKILEN*KKSCCVPW 555
            EN++ ++W++L   ++    L +V +  +     C  W
Sbjct: 83  MENLSRWIWNRLSPELDN---LFKVSVYRDSSGDACTYW 118


>UniRef50_A7HXX3 Cluster: 6-pyruvoyl tetrahydropterin synthase; n=1;
           Parvibaculum lavamentivorans DS-1|Rep: 6-pyruvoyl
           tetrahydropterin synthase - Parvibaculum lavamentivorans
           DS-1
          Length = 122

 Score = 50.8 bits (116), Expect = 2e-05
 Identities = 31/96 (32%), Positives = 55/96 (57%), Gaps = 2/96 (2%)
 Frame = +1

Query: 193 RLHSPFLSDEENKKVYGKCNNPNG--HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKT 366
           +++  FL D  +   Y +  +PN   HGH++ V+V +KG    +TG+V +  D+++ I  
Sbjct: 2   KIYKEFLFDAAHFLPYAEEGHPNRRMHGHSFRVVVWLKGKPAAETGIVRHFEDVEREI-M 60

Query: 367 AILEPLDHKNLDNDVPYFKTMASTTENVAIYVWDQL 474
           A+ E LDH +L N++   +    T E +A ++WD L
Sbjct: 61  AVREKLDH-HLLNEIEGLE--FPTLERIAAWIWDAL 93


>UniRef50_Q2LVK6 Cluster: Queuosine biosynthesis protein; n=5;
           Proteobacteria|Rep: Queuosine biosynthesis protein -
           Syntrophus aciditrophicus (strain SB)
          Length = 159

 Score = 49.6 bits (113), Expect = 5e-05
 Identities = 38/133 (28%), Positives = 73/133 (54%), Gaps = 2/133 (1%)
 Frame = +1

Query: 133 TMSSLP-IVSIIRRETFSSAHRLHSPFLSDEENKKVYGKCNNPNGHGHNYVVLVTVKGPV 309
           ++S +P +  I   E FS+AH L          +   G C +   HGHN+ V VTV+   
Sbjct: 30  SLSFMPGVFEISIEEQFSAAHAL----------RNYPGNCEHL--HGHNWAVEVTVECEE 77

Query: 310 DPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTENVAIYVWDQLQRIME 489
             + G+ ++  ++K+ ++ A L  LDH NL N++P F  +  ++EN+A +++++L R + 
Sbjct: 78  LNEIGIGIDFREVKQSVREA-LHRLDHVNL-NELPQFCDINPSSENIARHLYNELSRKLN 135

Query: 490 KPQL-LHEVKILE 525
             ++ +  V++ E
Sbjct: 136 TEKIRVSRVRVSE 148


>UniRef50_Q64Q92 Cluster: 6-pyruvoyl-tetrahydropterin synthase; n=5;
           Bacteroidales|Rep: 6-pyruvoyl-tetrahydropterin synthase
           - Bacteroides fragilis
          Length = 110

 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 34/106 (32%), Positives = 57/106 (53%)
 Frame = +1

Query: 157 SIIRRETFSSAHRLHSPFLSDEENKKVYGKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMN 336
           ++I+R   S+AH+L  P+ S         KC +   HGHN+++ V  +       GMV++
Sbjct: 3   TVIKRMEISAAHKLILPYRS---------KCASL--HGHNWIITVYCRSERLNADGMVVD 51

Query: 337 ITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTENVAIYVWDQL 474
            T +K+ +K    E LDH+NL+  +P+      T EN+A +V  Q+
Sbjct: 52  FTQIKQAVK----EKLDHRNLNEVLPF----NPTAENIARWVCKQI 89


>UniRef50_Q6MLY9 Cluster: 6-pyruvoyltetrahydropterin synthase; n=1;
           Bdellovibrio bacteriovorus|Rep:
           6-pyruvoyltetrahydropterin synthase - Bdellovibrio
           bacteriovorus
          Length = 135

 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 28/96 (29%), Positives = 58/96 (60%)
 Frame = +1

Query: 265 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTE 444
           HGH++ +++T+ G +DP+ G V++  D++  +K  +L+ +DH+ L N+VP  +    T+E
Sbjct: 45  HGHSFKLILTLVGDLDPKIGWVIDYNDIQALMK-PLLDQIDHRVL-NEVPGLEN--PTSE 100

Query: 445 NVAIYVWDQLQRIMEKPQLLHEVKILEN*KKSCCVP 552
            +A +++D+ +  +  P L+ +V + E     C  P
Sbjct: 101 LLAKWLYDKARPFL--PTLV-KVTVAETPATECSYP 133


>UniRef50_A6PRS0 Cluster: Putative uncharacterized protein; n=1;
           Victivallis vadensis ATCC BAA-548|Rep: Putative
           uncharacterized protein - Victivallis vadensis ATCC
           BAA-548
          Length = 112

 Score = 46.4 bits (105), Expect = 5e-04
 Identities = 26/89 (29%), Positives = 50/89 (56%), Gaps = 1/89 (1%)
 Frame = +1

Query: 265 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTE 444
           HGHNY + VTV+     + G+ ++   LK  +  A+L   DH NL +++  F+ +  T+E
Sbjct: 16  HGHNYKITVTVRSSELDEIGIALDFKKLKAEL-DALLAEYDHSNL-SELADFQAVNPTSE 73

Query: 445 NVAIYVWDQLQRIMEKPQL-LHEVKILEN 528
           N+A  ++ ++   M    + +H V++ E+
Sbjct: 74  NLARTIYRKISEKMNSGTIRVHRVRVGES 102


>UniRef50_Q74CF4 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase
           family protein; n=7; Bacteria|Rep: 6-pyruvoyl
           tetrahydrobiopterin synthase family protein - Geobacter
           sulfurreducens
          Length = 122

 Score = 45.2 bits (102), Expect = 0.001
 Identities = 29/95 (30%), Positives = 51/95 (53%)
 Frame = +1

Query: 196 LHSPFLSDEENKKVYGKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAIL 375
           +H+ F +        G C N   HGHN+ V V+V      + G+ ++   LK+     +L
Sbjct: 6   IHTSFAAAHCLINYQGDCENL--HGHNWRVEVSVTARELDKAGLGIDFKVLKQE-TNGLL 62

Query: 376 EPLDHKNLDNDVPYFKTMASTTENVAIYVWDQLQR 480
             LDHK L N++  FK ++ ++EN++ Y++ +L R
Sbjct: 63  RTLDHKYL-NELEPFKEISPSSENISRYLYHELSR 96


>UniRef50_A4J5C6 Cluster: Putative uncharacterized protein; n=2;
           Peptococcaceae|Rep: Putative uncharacterized protein -
           Desulfotomaculum reducens MI-1
          Length = 128

 Score = 45.2 bits (102), Expect = 0.001
 Identities = 30/93 (32%), Positives = 50/93 (53%), Gaps = 5/93 (5%)
 Frame = +1

Query: 265 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYF--KTMAST 438
           HGH + V V V G    + GM+++  D+KK + T I+   DH  + ND+P F    +  T
Sbjct: 27  HGHTWTVEVKVFGKELNELGMLIDFKDIKKQLAT-IINEFDHSYI-NDLPGFGEDGVNPT 84

Query: 439 TENVAIYVWDQLQRIMEKPQL---LHEVKILEN 528
            EN++ Y++  L + +   Q+   L EV + E+
Sbjct: 85  AENLSYYIFQTLAQRISSIQMGVKLKEVSVWES 117


>UniRef50_Q3ZW85 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase;
           n=3; Dehalococcoides|Rep: 6-pyruvoyl tetrahydrobiopterin
           synthase - Dehalococcoides sp. (strain CBDB1)
          Length = 123

 Score = 44.8 bits (101), Expect = 0.002
 Identities = 30/85 (35%), Positives = 48/85 (56%), Gaps = 1/85 (1%)
 Frame = +1

Query: 241 GKCNNPNGHGHNYVVLVTVK-GPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPY 417
           GKC N   HGH Y V + VK G +D + GM  + + LK  +   +L+  DH  L ND+  
Sbjct: 21  GKCENL--HGHRYEVALKVKTGELD-ECGMGADFSLLKTRLNE-VLQSYDHTCL-NDLTP 75

Query: 418 FKTMASTTENVAIYVWDQLQRIMEK 492
           F  +  + EN+A  ++D+L+ ++ K
Sbjct: 76  FDNINPSAENIAKDIYDKLKTVINK 100


>UniRef50_A1HNF1 Cluster: Putative uncharacterized protein; n=1;
           Thermosinus carboxydivorans Nor1|Rep: Putative
           uncharacterized protein - Thermosinus carboxydivorans
           Nor1
          Length = 130

 Score = 44.8 bits (101), Expect = 0.002
 Identities = 40/119 (33%), Positives = 60/119 (50%), Gaps = 6/119 (5%)
 Frame = +1

Query: 148 PIVSIIRRETFSSAHRLHSPFLSDEENKKVYGKCNNPNGHGHNYVVLVTVK---GPV--- 309
           P V   +  TF +AH     FL   E     GKC     HGH Y + VTV+   G V   
Sbjct: 4   PTVRTTKIFTFDAAH-----FLPGHE-----GKCAQM--HGHTYRLEVTVERKDGGVATG 51

Query: 310 DPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTENVAIYVWDQLQRIM 486
            P+ GMV++   L   IK  +++ LDHK L++  P+      T+EN+A +++ +L  I+
Sbjct: 52  GPEDGMVIDFGRLSALIKDRVVDKLDHKVLNDCFPF----RPTSENMARHIFIELSAIL 106


>UniRef50_Q89ZC4 Cluster: 6-pyruvoyl-tetrahydropterin synthase; n=3;
           Bacteroidales|Rep: 6-pyruvoyl-tetrahydropterin synthase
           - Bacteroides thetaiotaomicron
          Length = 124

 Score = 44.4 bits (100), Expect = 0.002
 Identities = 33/106 (31%), Positives = 55/106 (51%)
 Frame = +1

Query: 157 SIIRRETFSSAHRLHSPFLSDEENKKVYGKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMN 336
           ++I+R   S++H+L  P+ S         KC +   HGHN+++ V  +       GMV++
Sbjct: 3   TVIKRMEISASHKLVLPYRS---------KCASL--HGHNWIITVYCRSSRLNSEGMVVD 51

Query: 337 ITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTENVAIYVWDQL 474
            T     IK  + E LDH+NL+  +P+      T EN+A +V  Q+
Sbjct: 52  FT----RIKEVVTEKLDHQNLNEVLPF----NPTAENIARWVCRQI 89


>UniRef50_Q3J9J8 Cluster: 6-pyruvoyl tetrahydropterin synthase; n=1;
           Nitrosococcus oceani ATCC 19707|Rep: 6-pyruvoyl
           tetrahydropterin synthase - Nitrosococcus oceani (strain
           ATCC 19707 / NCIMB 11848)
          Length = 99

 Score = 44.4 bits (100), Expect = 0.002
 Identities = 25/72 (34%), Positives = 39/72 (54%)
 Frame = +1

Query: 265 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTE 444
           HGHN+ + V V      Q GMVM+  D+K+  +  +   LDH+ L ND+  F  +  T E
Sbjct: 2   HGHNWKLEVEVTAQALDQQGMVMDFKDIKESAR-ELCAQLDHRYL-NDISPFDLINPTAE 59

Query: 445 NVAIYVWDQLQR 480
           N+A + +  L +
Sbjct: 60  NLAAFFYRGLSK 71


>UniRef50_A5D2E2 Cluster: 6-pyruvoyl-tetrahydropterin synthase; n=1;
           Pelotomaculum thermopropionicum SI|Rep:
           6-pyruvoyl-tetrahydropterin synthase - Pelotomaculum
           thermopropionicum SI
          Length = 129

 Score = 43.6 bits (98), Expect = 0.004
 Identities = 26/96 (27%), Positives = 53/96 (55%), Gaps = 2/96 (2%)
 Frame = +1

Query: 196 LHSPFLSDEENKKVYGKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAIL 375
           + + F +    K   G C+    HGH ++V   ++G    Q GM+++  ++K  +++A+ 
Sbjct: 6   VRTSFAAAHSIKGYDGPCSRM--HGHTWLVEAVLRGGQLDQKGMLVDFKEVKNILRSAVG 63

Query: 376 EPLDHKNLDNDVPYF--KTMASTTENVAIYVWDQLQ 477
           E LDH+NL+   P+      + T EN+A Y++ +++
Sbjct: 64  E-LDHQNLNEIKPFAGGSGDSPTAENIARYLFCRIK 98


>UniRef50_A4CIF9 Cluster: 6-pyruvoyl tetrahydropterin synthase;
           n=14; Bacteroidetes|Rep: 6-pyruvoyl tetrahydropterin
           synthase - Robiginitalea biformata HTCC2501
          Length = 151

 Score = 43.2 bits (97), Expect = 0.005
 Identities = 28/74 (37%), Positives = 43/74 (58%), Gaps = 6/74 (8%)
 Frame = +1

Query: 241 GKCNNPNGHGHNYVVLVTVKG-PVDP----QTGMVMNITDLKKYIKTAILEPLDHKNLDN 405
           GKC N   HGH+Y + VTV G P+      + GMVM+  DLKK ++  +++  DH  + N
Sbjct: 23  GKCRNV--HGHSYHLSVTVIGTPIAEDGAVKLGMVMDFGDLKKVVREEVVDRFDHATIFN 80

Query: 406 -DVPYFKTMASTTE 444
            + P+ + +A T E
Sbjct: 81  RNTPHVE-LARTLE 93


>UniRef50_P44123 Cluster: Putative 6-pyruvoyl tetrahydrobiopterin
           synthase; n=21; Proteobacteria|Rep: Putative 6-pyruvoyl
           tetrahydrobiopterin synthase - Haemophilus influenzae
          Length = 141

 Score = 43.2 bits (97), Expect = 0.005
 Identities = 21/53 (39%), Positives = 31/53 (58%), Gaps = 3/53 (5%)
 Frame = +1

Query: 241 GKCNNPNGHGHNYVVLVTVKGPV---DPQTGMVMNITDLKKYIKTAILEPLDH 390
           GKC N   HGH Y + V + G +     +  MV++ +DLK  +K  IL+P+DH
Sbjct: 21  GKCQNL--HGHTYKLQVEISGDLYKSGAKKAMVIDFSDLKSIVKKVILDPMDH 71


>UniRef50_O29809 Cluster: Putative 6-pyruvoyl tetrahydrobiopterin
           synthase; n=1; Archaeoglobus fulgidus|Rep: Putative
           6-pyruvoyl tetrahydrobiopterin synthase - Archaeoglobus
           fulgidus
          Length = 115

 Score = 43.2 bits (97), Expect = 0.005
 Identities = 27/88 (30%), Positives = 46/88 (52%)
 Frame = +1

Query: 265 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTE 444
           HGHN+ V V + G V  + GMVM+  DLK+ +   + +  DH  L+  +        T+E
Sbjct: 29  HGHNFKVEVEISGKVK-ENGMVMDFFDLKRIVNEVVAK-FDHTLLNEQIE-----IPTSE 81

Query: 445 NVAIYVWDQLQRIMEKPQLLHEVKILEN 528
           N+ + ++ +L    EK   +  V++ EN
Sbjct: 82  NICLRIFSEL---AEKGLNVRRVRVAEN 106


>UniRef50_Q82UG9 Cluster: 6-pyruvoyl tetrahydropterin synthase;
           n=32; Betaproteobacteria|Rep: 6-pyruvoyl
           tetrahydropterin synthase - Nitrosomonas europaea
          Length = 160

 Score = 42.7 bits (96), Expect = 0.006
 Identities = 20/49 (40%), Positives = 32/49 (65%), Gaps = 5/49 (10%)
 Frame = +1

Query: 259 NGHGHNYVVLVTVKGPVD-----PQTGMVMNITDLKKYIKTAILEPLDH 390
           N HGH YV+ VT+ G +      P+ GMVM+ +D+K+ I+ A+++  DH
Sbjct: 24  NLHGHRYVLEVTIAGGIIADAGVPEQGMVMDFSDVKRVIREALVDRWDH 72


>UniRef50_Q4LA59 Cluster: Similar to 6-pyruvoyl tetrahydropterin
           synthase; n=1; Staphylococcus haemolyticus JCSC1435|Rep:
           Similar to 6-pyruvoyl tetrahydropterin synthase -
           Staphylococcus haemolyticus (strain JCSC1435)
          Length = 143

 Score = 42.7 bits (96), Expect = 0.006
 Identities = 24/89 (26%), Positives = 49/89 (55%), Gaps = 2/89 (2%)
 Frame = +1

Query: 265 HGHNYVVLVTVKGPV-DPQTGMVMNITDLKKYIKTAILEP-LDHKNLDNDVPYFKTMAST 438
           H H+Y + V V  P+ D   G+  N  D    I   ++EP L+H+ ++  +P    M +T
Sbjct: 46  HNHSYRLYVDVLSPIGDYGLGLDFNEVDA---IYNKVIEPKLNHQLINETLP---DMNTT 99

Query: 439 TENVAIYVWDQLQRIMEKPQLLHEVKILE 525
            EN+A+++WD+ ++ +     ++ +++ E
Sbjct: 100 AENIAMWIWDEFEQHLPGEHCMYALQLFE 128


>UniRef50_Q9UYV0 Cluster: PtpS-like 6-pyruvoyl-tetrahydropterin
           synthase; n=4; Thermococcaceae|Rep: PtpS-like
           6-pyruvoyl-tetrahydropterin synthase - Pyrococcus abyssi
          Length = 115

 Score = 42.7 bits (96), Expect = 0.006
 Identities = 29/85 (34%), Positives = 51/85 (60%)
 Frame = +1

Query: 265 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTE 444
           HGH + + V V+G +  + G +M+ T+L+K +   + E L+H+NL+     F     TTE
Sbjct: 27  HGHTFFLEVAVEGEI--KRGYIMDFTELRKIVDDIVKE-LNHRNLNK---IFDN--PTTE 78

Query: 445 NVAIYVWDQLQRIMEKPQLLHEVKI 519
           NVA+++    +++ EK  L H+VK+
Sbjct: 79  NVALWI---AEKVEEK--LPHKVKL 98


>UniRef50_Q2IKV5 Cluster: 6-pyruvoyl tetrahydropterin synthase; n=2;
           Anaeromyxobacter|Rep: 6-pyruvoyl tetrahydropterin
           synthase - Anaeromyxobacter dehalogenans (strain 2CP-C)
          Length = 138

 Score = 41.1 bits (92), Expect = 0.019
 Identities = 25/80 (31%), Positives = 42/80 (52%)
 Frame = +1

Query: 241 GKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYF 420
           GKC     HGHN+ V V  +     + GMV++  DL+K +   +    DH+N+ N+V  F
Sbjct: 33  GKCERL--HGHNWRVRVHARASTLNRIGMVIDFADLQKLV-AEVGSRFDHQNV-NEVAPF 88

Query: 421 KTMASTTENVAIYVWDQLQR 480
               +T E +A + + ++ R
Sbjct: 89  DQENTTAELIARFFYREMSR 108


>UniRef50_Q8TIF6 Cluster: 6-pyruvoyltetrahydropterin synthase; n=5;
           Euryarchaeota|Rep: 6-pyruvoyltetrahydropterin synthase -
           Methanosarcina acetivorans
          Length = 120

 Score = 40.7 bits (91), Expect = 0.025
 Identities = 24/60 (40%), Positives = 35/60 (58%)
 Frame = +1

Query: 238 YGKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPY 417
           +GKC     HGH Y + V V+G V  + GMV++  DLKK IK   L+  DH  L++ + +
Sbjct: 24  HGKCGRV--HGHTYKIEVVVEGEVR-ENGMVIDFYDLKKGIKET-LQEYDHTLLNDLIEF 79


>UniRef50_Q7UGM2 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase;
           n=1; Pirellula sp.|Rep: 6-pyruvoyl tetrahydrobiopterin
           synthase - Rhodopirellula baltica
          Length = 137

 Score = 40.3 bits (90), Expect = 0.034
 Identities = 30/76 (39%), Positives = 36/76 (47%)
 Frame = +1

Query: 163 IRRETFSSAHRLHSPFLSDEENKKVYGKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNIT 342
           +RR TF S HRL    +  E      GKC N   HGHNYV+ V V G      G +++  
Sbjct: 1   MRRFTFCSGHRL----VGHE------GKCQNL--HGHNYVLEVYVTGEEQDAIGRILDFK 48

Query: 343 DLKKYIKTAILEPLDH 390
            LK   K  I E  DH
Sbjct: 49  QLKTRCKNWIDENWDH 64


>UniRef50_O31676 Cluster: YkvK protein; n=25; Bacillales|Rep: YkvK
           protein - Bacillus subtilis
          Length = 149

 Score = 39.5 bits (88), Expect = 0.059
 Identities = 25/77 (32%), Positives = 38/77 (49%), Gaps = 2/77 (2%)
 Frame = +1

Query: 265 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPL--DHKNLDNDVPYFKTMAST 438
           HGH Y V +TV G     +G ++N + LKK +       L  DH++   D  Y      T
Sbjct: 44  HGHTYTVNITVAGDELDDSGFLVNFSVLKKLVHGNYDHTLLNDHEDFSQDDRY---SLPT 100

Query: 439 TENVAIYVWDQLQRIME 489
           TE VA  ++D +Q  ++
Sbjct: 101 TEVVAKTIYDNVQAYLD 117


>UniRef50_A6GHT7 Cluster: Putative uncharacterized protein; n=1;
           Plesiocystis pacifica SIR-1|Rep: Putative
           uncharacterized protein - Plesiocystis pacifica SIR-1
          Length = 129

 Score = 39.1 bits (87), Expect = 0.078
 Identities = 21/72 (29%), Positives = 40/72 (55%)
 Frame = +1

Query: 265 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTE 444
           HGHNY V + V      + GM ++   ++   +  ++  +DH+ L N++P F  +  T E
Sbjct: 30  HGHNYKVEIEVACEQLDELGMGVDFRAVRAAARE-VVGVIDHRFL-NEIPPFTEVNPTAE 87

Query: 445 NVAIYVWDQLQR 480
           ++A Y+++ L R
Sbjct: 88  HIAAYIYEGLAR 99


>UniRef50_O66626 Cluster: Putative 6-pyruvoyl tetrahydrobiopterin
           synthase; n=2; Aquifex aeolicus|Rep: Putative 6-pyruvoyl
           tetrahydrobiopterin synthase - Aquifex aeolicus
          Length = 162

 Score = 39.1 bits (87), Expect = 0.078
 Identities = 35/117 (29%), Positives = 57/117 (48%), Gaps = 18/117 (15%)
 Frame = +1

Query: 229 KKVYGKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNL--- 399
           +K   KC N   HGH+YV+ VTV      +  MVM+   +K  +K  ++E +DH  +   
Sbjct: 33  EKPVNKCVNL--HGHSYVLEVTVGSDTLSEQDMVMDFYHVKNALK-GLIEEIDHSFIIDV 89

Query: 400 -DNDVPYFKTMAS--------------TTENVAIYVWDQLQRIMEKPQLLHEVKILE 525
            D   P  K +A               T E +A + +D L++ +E+  LL EVK+++
Sbjct: 90  NDPMYPELKDVAEKYGAMKIFPVEFCPTAEALAKFFYDFLKKRLEEAGLLGEVKVVK 146


>UniRef50_A1SFN0 Cluster: Putative uncharacterized protein; n=1;
           Nocardioides sp. JS614|Rep: Putative uncharacterized
           protein - Nocardioides sp. (strain BAA-499 / JS614)
          Length = 118

 Score = 38.3 bits (85), Expect = 0.14
 Identities = 30/86 (34%), Positives = 47/86 (54%), Gaps = 3/86 (3%)
 Frame = +1

Query: 154 VSIIRRETFSSAHRLHSPFLSDEENKKVYGKCNNPNGHGHNYVVLVTVKGPVDPQTGMVM 333
           +SI+RR  F +AH L  P+          GKC+    HGH+YV+ V V G +D + G+VM
Sbjct: 3   ISIVRRYRFEAAHTL--PWHP--------GKCSRI--HGHSYVLEVHVTGELDDR-GVVM 49

Query: 334 NITDLKKYIKTAILE---PLDHKNLD 402
           +  ++   +   +LE    LDH +L+
Sbjct: 50  DFAEVDAIVDQHVLEGPAGLDHVDLN 75


>UniRef50_Q55798 Cluster: Putative 6-pyruvoyl tetrahydrobiopterin
           synthase; n=4; Cyanobacteria|Rep: Putative 6-pyruvoyl
           tetrahydrobiopterin synthase - Synechocystis sp. (strain
           PCC 6803)
          Length = 129

 Score = 38.3 bits (85), Expect = 0.14
 Identities = 29/98 (29%), Positives = 50/98 (51%), Gaps = 3/98 (3%)
 Frame = +1

Query: 241 GKCNNPNGH---GHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDV 411
           GKC   +GH   G  YV    +K     +TGMVM+ + LK ++   +   LDH  L++ +
Sbjct: 21  GKCRRLHGHSFRGRVYVASDRLK-TTGSETGMVMDFSVLKAHLDPLVKNHLDHYYLNDSL 79

Query: 412 PYFKTMASTTENVAIYVWDQLQRIMEKPQLLHEVKILE 525
                 + T+E +A +++ +L+        LH V++LE
Sbjct: 80  ---GLESPTSEAIAAWIFAKLEEAGVPG--LHSVEVLE 112


>UniRef50_Q1D8H8 Cluster: Putative uncharacterized protein; n=1;
           Myxococcus xanthus DK 1622|Rep: Putative uncharacterized
           protein - Myxococcus xanthus (strain DK 1622)
          Length = 209

 Score = 37.9 bits (84), Expect = 0.18
 Identities = 23/71 (32%), Positives = 37/71 (52%)
 Frame = +1

Query: 265 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTE 444
           H H++ V V VK        ++++  DL+  I   +   L   N+ N+ PYFKT+  T E
Sbjct: 110 HTHDWWVRVWVKARALNHWDVIIDFKDLQDII-VRVCRELHDTNI-NEHPYFKTVNCTAE 167

Query: 445 NVAIYVWDQLQ 477
            V  YV+ Q++
Sbjct: 168 RVTEYVFKQVE 178


>UniRef50_A6GQ16 Cluster: Putative 6-pyruvoyl tetrahydrobiopterin
           synthase; n=1; Limnobacter sp. MED105|Rep: Putative
           6-pyruvoyl tetrahydrobiopterin synthase - Limnobacter
           sp. MED105
          Length = 116

 Score = 37.9 bits (84), Expect = 0.18
 Identities = 24/76 (31%), Positives = 41/76 (53%)
 Frame = +1

Query: 256 PNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMAS 435
           P  HGH+Y   V  +GP     G V+  + L +++  A+ + LDH  L+  +        
Sbjct: 19  PGLHGHSYTAEVWFEGPATD--GYVVPESLLTQHVG-AVHKRLDHSYLNEFIEL-----P 70

Query: 436 TTENVAIYVWDQLQRI 483
           T+EN+A ++WDQL+ +
Sbjct: 71  TSENIARWIWDQLRPV 86


>UniRef50_Q1NNT9 Cluster: Putative uncharacterized protein; n=3;
           Bacteria|Rep: Putative uncharacterized protein - delta
           proteobacterium MLMS-1
          Length = 154

 Score = 37.5 bits (83), Expect = 0.24
 Identities = 22/80 (27%), Positives = 42/80 (52%)
 Frame = +1

Query: 265 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTE 444
           H H Y + V + GP   + G +++I +L   +   + E  + + L ND+P F  +  + E
Sbjct: 54  HAHCYRLEVALDGPELNEHGFLVDIVELAGNLDL-VQEAYEDRIL-NDLPEFAGLNPSIE 111

Query: 445 NVAIYVWDQLQRIMEKPQLL 504
           N+A  +W +L ++    +LL
Sbjct: 112 NLARLIWQRLSQLPASDKLL 131


>UniRef50_Q12DE9 Cluster: Putative uncharacterized protein; n=4;
           Comamonadaceae|Rep: Putative uncharacterized protein -
           Polaromonas sp. (strain JS666 / ATCC BAA-500)
          Length = 120

 Score = 37.1 bits (82), Expect = 0.31
 Identities = 20/47 (42%), Positives = 27/47 (57%)
 Frame = +1

Query: 265 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDN 405
           HGH Y   V V G  D  TGMVM++  +++ I   + E LDH  LD+
Sbjct: 30  HGHTYNAEVFVAGEPDEATGMVMDLGLVRREI-AVLREELDHHLLDD 75


>UniRef50_A3UD70 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase,
           putative; n=1; Oceanicaulis alexandrii HTCC2633|Rep:
           6-pyruvoyl tetrahydrobiopterin synthase, putative -
           Oceanicaulis alexandrii HTCC2633
          Length = 132

 Score = 37.1 bits (82), Expect = 0.31
 Identities = 29/107 (27%), Positives = 54/107 (50%), Gaps = 3/107 (2%)
 Frame = +1

Query: 175 TFSSAH-RLHSPFLSDEENKKVYGKCNNPNG--HGHNYVVLVTVKGPVDPQTGMVMNITD 345
           T +  H  +   F  D  +   +   N+P    HGH++   VT+ G    ++GMV +  +
Sbjct: 8   TMTDLHLEISKDFTFDAAHHFEHKDANHPFSRMHGHSFAGTVTLTGSRAAESGMVKDFWE 67

Query: 346 LKKYIKTAILEPLDHKNLDNDVPYFKTMASTTENVAIYVWDQLQRIM 486
           ++  I   I E LDH+ L NDV   +    + E +A +V+++L++ +
Sbjct: 68  IEAEI-NKIREQLDHRLL-NDVEGLE--HPSLEAIAYWVFERLEKTL 110


>UniRef50_A4EHB1 Cluster: 6-pyruvoyl tetrahydropterin synthase; n=6;
           Bacteria|Rep: 6-pyruvoyl tetrahydropterin synthase -
           Roseobacter sp. CCS2
          Length = 131

 Score = 36.7 bits (81), Expect = 0.41
 Identities = 23/71 (32%), Positives = 39/71 (54%)
 Frame = +1

Query: 265 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTE 444
           HG  +VV          + G+V+++    + +  A L+PL + NLD +VP FK   +TTE
Sbjct: 28  HGATFVVDAAFYTKDLDENGLVVDMGLALEALADA-LKPLKYANLD-EVPAFKGKITTTE 85

Query: 445 NVAIYVWDQLQ 477
            +  ++W QL+
Sbjct: 86  FLCHHIWQQLR 96


>UniRef50_UPI000038E306 Cluster: hypothetical protein Faci_03001749;
           n=1; Ferroplasma acidarmanus fer1|Rep: hypothetical
           protein Faci_03001749 - Ferroplasma acidarmanus fer1
          Length = 157

 Score = 35.5 bits (78), Expect = 0.96
 Identities = 26/86 (30%), Positives = 44/86 (51%)
 Frame = +1

Query: 136 MSSLPIVSIIRRETFSSAHRLHSPFLSDEENKKVYGKCNNPNGHGHNYVVLVTVKGPVDP 315
           M  + +V  ++  T+SS H     ++ D E      KC N   HGH+Y + V +      
Sbjct: 1   MYRIEVVGALKGLTWSSGH-----YVPDNE------KCKN--FHGHDYSIDVIIDSDGVK 47

Query: 316 QTGMVMNITDLKKYIKTAILEPLDHK 393
            +GM ++ T +K+ IK  ++E +DHK
Sbjct: 48  ASGMAIDFTIVKQAIK-PVIENMDHK 72


>UniRef50_Q8KCI4 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase,
           putative; n=9; Chlorobiaceae|Rep: 6-pyruvoyl
           tetrahydrobiopterin synthase, putative - Chlorobium
           tepidum
          Length = 178

 Score = 35.1 bits (77), Expect = 1.3
 Identities = 18/47 (38%), Positives = 28/47 (59%), Gaps = 5/47 (10%)
 Frame = +1

Query: 265 HGHNYVVLVTVKGPV-----DPQTGMVMNITDLKKYIKTAILEPLDH 390
           HGH  V++ TV+GPV     D + GMV++   L++ +   I + LDH
Sbjct: 62  HGHRGVIVATVEGPVIDRAGDAEEGMVIDFKFLRQIMDEHIHDQLDH 108


>UniRef50_Q7RP45 Cluster: Putative uncharacterized protein PY01616;
            n=2; Plasmodium (Vinckeia)|Rep: Putative uncharacterized
            protein PY01616 - Plasmodium yoelii yoelii
          Length = 1189

 Score = 35.1 bits (77), Expect = 1.3
 Identities = 22/62 (35%), Positives = 33/62 (53%)
 Frame = +2

Query: 377  NHSTIRI*IMMFHTSKLWQVLQKMSQYMSGTNFKE*WKNHNYCMRLRS*KTEKNHVVYRG 556
            N++ I+  I   H S+L+QV    + Y+SG N K  +KN       ++ K EKN   Y+ 
Sbjct: 976  NYNKIQYFISQLHQSQLYQVAFSYAIYLSGKNEKN-YKNEKNYKNEKNYKNEKN---YKS 1031

Query: 557  GN 562
            GN
Sbjct: 1032 GN 1033


>UniRef50_Q4Y977 Cluster: 6-pyruvoyl tetrahydropterin synthase,
           putative; n=6; Plasmodium|Rep: 6-pyruvoyl
           tetrahydropterin synthase, putative - Plasmodium
           chabaudi
          Length = 173

 Score = 35.1 bits (77), Expect = 1.3
 Identities = 18/43 (41%), Positives = 26/43 (60%)
 Frame = +1

Query: 265 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHK 393
           HGHNY V + VKG +    G V++ + LKK +K  I   +DH+
Sbjct: 41  HGHNYNVSLKVKGHIQ-SDGYVVDFSILKKIVKN-ICNTIDHR 81


>UniRef50_A7BS03 Cluster: 6-pyruvoyl tetrahydropterin synthase; n=1;
           Beggiatoa sp. PS|Rep: 6-pyruvoyl tetrahydropterin
           synthase - Beggiatoa sp. PS
          Length = 148

 Score = 34.7 bits (76), Expect = 1.7
 Identities = 25/96 (26%), Positives = 41/96 (42%), Gaps = 1/96 (1%)
 Frame = +1

Query: 241 GKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDV-PY 417
           GKC +   HGH+   ++ +        G VM+  D+K  +K  I +  DH  L N+  P 
Sbjct: 23  GKCRHV--HGHSGEAIIELASNTLNDNGFVMDFADVKTPLKKWINQFWDHAYLANESDPL 80

Query: 418 FKTMASTTENVAIYVWDQLQRIMEKPQLLHEVKILE 525
                S   N+  +  +    +M +  L  +  ILE
Sbjct: 81  LPAFKSENMNIYTFPEEPTAEVMAR-HLFEQAAILE 115


>UniRef50_A1WW30 Cluster: Putative uncharacterized protein; n=1;
           Halorhodospira halophila SL1|Rep: Putative
           uncharacterized protein - Halorhodospira halophila
           (strain DSM 244 / SL1) (Ectothiorhodospirahalophila
           (strain DSM 244 / SL1))
          Length = 258

 Score = 34.3 bits (75), Expect = 2.2
 Identities = 17/46 (36%), Positives = 24/46 (52%)
 Frame = +1

Query: 265 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLD 402
           HGH Y + V V  P+D   G  ++  D+K      + E LDH+ LD
Sbjct: 168 HGHGYRLRVHVTAPLDRVLGWTLDYGDVKAAF-APVREALDHQRLD 212


>UniRef50_Q98S03 Cluster: Putative uncharacterized protein orf305;
           n=1; Guillardia theta|Rep: Putative uncharacterized
           protein orf305 - Guillardia theta (Cryptomonas phi)
          Length = 305

 Score = 34.3 bits (75), Expect = 2.2
 Identities = 15/62 (24%), Positives = 32/62 (51%)
 Frame = -3

Query: 390 MVEWFQDGCFYVFLEVSYIHHHTSLRIYRTLYCYKNNIIMTVTIRIVAFTINFFVLFVT* 211
           ++ ++    F++F + SY    +   +++ ++ +K NII    +    F I FF +F T 
Sbjct: 229 LISYYLIDFFHIFKKYSYKLIFSKCIVFKNIFKFKQNIIFVKKLYCEEFLIKFFTIFKTR 288

Query: 210 KR 205
           +R
Sbjct: 289 RR 290


>UniRef50_Q4A0G7 Cluster: Putative 6-pyruvoyl tetrahydrobiopterin
           synthase; n=1; Staphylococcus saprophyticus subsp.
           saprophyticus ATCC 15305|Rep: Putative 6-pyruvoyl
           tetrahydrobiopterin synthase - Staphylococcus
           saprophyticus subsp. saprophyticus (strain ATCC 15305
           /DSM 20229)
          Length = 142

 Score = 33.9 bits (74), Expect = 2.9
 Identities = 16/68 (23%), Positives = 35/68 (51%)
 Frame = +1

Query: 322 GMVMNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTENVAIYVWDQLQRIMEKPQL 501
           G+ M+  ++ K  +  I   +D + ++  +P   T   T EN+AI++W Q  + + +   
Sbjct: 63  GLAMDFNEVDKLYEREIAPYIDGQLVNETLPEMNT---TAENIAIWIWHQFNKHLPENNS 119

Query: 502 LHEVKILE 525
           L +++  E
Sbjct: 120 LQKLEFFE 127


>UniRef50_O27296 Cluster: Putative 6-pyruvoyl tetrahydrobiopterin
           synthase; n=4; Euryarchaeota|Rep: Putative 6-pyruvoyl
           tetrahydrobiopterin synthase - Methanobacterium
           thermoautotrophicum
          Length = 161

 Score = 33.9 bits (74), Expect = 2.9
 Identities = 17/45 (37%), Positives = 25/45 (55%)
 Frame = +1

Query: 265 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNL 399
           HGH+Y+V V V+G    + G V +  D+K  ++  I    DHK L
Sbjct: 33  HGHSYIVDVKVEGKRSGKHGFVADFKDVKDIVR-RICSEFDHKLL 76


>UniRef50_Q890G9 Cluster: Putative uncharacterized protein lp_0052;
           n=1; Lactobacillus plantarum|Rep: Putative
           uncharacterized protein lp_0052 - Lactobacillus
           plantarum
          Length = 122

 Score = 33.5 bits (73), Expect = 3.9
 Identities = 20/70 (28%), Positives = 41/70 (58%), Gaps = 1/70 (1%)
 Frame = +1

Query: 343 DLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTENVAIYVWDQLQR-IMEKPQLLHEVKI 519
           D++K +  A L+ L  K L ND+P FKT+  T ENV  Y++ ++ + + +    L  +++
Sbjct: 51  DIEKNLHQA-LDELSGKFL-NDLPEFKTVNPTVENVTEYLFTKIDKTLRDNGAQLLRIEV 108

Query: 520 LEN*KKSCCV 549
            ++  ++ C+
Sbjct: 109 SDSPTRAYCI 118


>UniRef50_Q7NSB8 Cluster: Probable 6-pyruvoyltetrahydrobiopterin
           synthase; n=1; Chromobacterium violaceum|Rep: Probable
           6-pyruvoyltetrahydrobiopterin synthase - Chromobacterium
           violaceum
          Length = 239

 Score = 33.5 bits (73), Expect = 3.9
 Identities = 17/48 (35%), Positives = 26/48 (54%)
 Frame = +1

Query: 259 NGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLD 402
           N  GH+Y+V + + G +D   G +++  D+K   K  I   LDH  LD
Sbjct: 139 NYTGHSYLVRLMLSGGIDRTMGWLLDFGDVKDRFK-PIYRQLDHNPLD 185


>UniRef50_Q0RM63 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase;
           n=1; Frankia alni ACN14a|Rep: 6-pyruvoyl
           tetrahydrobiopterin synthase - Frankia alni (strain
           ACN14a)
          Length = 130

 Score = 33.5 bits (73), Expect = 3.9
 Identities = 26/104 (25%), Positives = 51/104 (49%)
 Frame = +1

Query: 142 SLPIVSIIRRETFSSAHRLHSPFLSDEENKKVYGKCNNPNGHGHNYVVLVTVKGPVDPQT 321
           ++P   I +   FS++HRL S   +D +  ++         HGHNY V V ++G      
Sbjct: 2   TMPAFEISKTFEFSASHRL-SGLPADHKCARL---------HGHNYTVRVQLRGETLDPV 51

Query: 322 GMVMNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTENVA 453
           G +++  +L   ++  I   LDH++L+  + +  T     +++A
Sbjct: 52  GFLLDYGELSP-VRDWIDAALDHQHLNACLDFNPTAELLAQHLA 94


>UniRef50_Q97UC3 Cluster: Putative uncharacterized protein; n=1;
           Sulfolobus solfataricus|Rep: Putative uncharacterized
           protein - Sulfolobus solfataricus
          Length = 334

 Score = 33.5 bits (73), Expect = 3.9
 Identities = 18/52 (34%), Positives = 32/52 (61%)
 Frame = -3

Query: 372 DGCFYVFLEVSYIHHHTSLRIYRTLYCYKNNIIMTVTIRIVAFTINFFVLFV 217
           +G FY++L V+YI ++T  RI   +  ++ N+ +T+TI   + T  F  LF+
Sbjct: 85  NGSFYLYLPVAYIQNNT--RINVIINSFQKNVNLTLTIPNSSTTFAFSSLFL 134


>UniRef50_Q8YJI9 Cluster: VACUOLAR ATP SYNTHASE 16 KD PROTEOLIPID
           SUBUNIT; n=7; Alphaproteobacteria|Rep: VACUOLAR ATP
           SYNTHASE 16 KD PROTEOLIPID SUBUNIT - Brucella melitensis
          Length = 148

 Score = 33.1 bits (72), Expect = 5.1
 Identities = 21/68 (30%), Positives = 37/68 (54%)
 Frame = +1

Query: 265 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTE 444
           HGHNY+V V +  P     G V +  +L   +K  I +  DH++L++ + + +T   T E
Sbjct: 29  HGHNYIVEVELSAPDLDTHGFVRDYHELAA-LKHYIDDTFDHRHLNDVLGHEQT---TAE 84

Query: 445 NVAIYVWD 468
            +A + +D
Sbjct: 85  RLAKHFFD 92


>UniRef50_Q8FYB2 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase,
           putative; n=21; Bacteria|Rep: 6-pyruvoyl
           tetrahydrobiopterin synthase, putative - Brucella suis
          Length = 121

 Score = 33.1 bits (72), Expect = 5.1
 Identities = 21/68 (30%), Positives = 37/68 (54%)
 Frame = +1

Query: 265 HGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTE 444
           HGHNY+V V +  P     G V +  +L   +K  I +  DH++L++ + + +T   T E
Sbjct: 29  HGHNYIVEVELSAPDLDTHGFVRDYHELAA-LKHYIDDTFDHRHLNDVLGHEQT---TAE 84

Query: 445 NVAIYVWD 468
            +A + +D
Sbjct: 85  RLAKHFFD 92


>UniRef50_Q8IIK5 Cluster: Putative uncharacterized protein; n=4;
            Plasmodium|Rep: Putative uncharacterized protein -
            Plasmodium falciparum (isolate 3D7)
          Length = 2966

 Score = 33.1 bits (72), Expect = 5.1
 Identities = 26/130 (20%), Positives = 52/130 (40%)
 Frame = +1

Query: 127  NYTMSSLPIVSIIRRETFSSAHRLHSPFLSDEENKKVYGKCNNPNGHGHNYVVLVTVKGP 306
            NYT S     +   + +F++   +++  ++++++   YG  N+ + H  N       K  
Sbjct: 1336 NYTCSVYQNSNCSNKNSFNNKDHIYNNTMNNDKDTYKYGTLNSNSDHKMNICDEKIKKNK 1395

Query: 307  VDPQTGMVMNITDLKKYIKTAILEPLDHKNLDNDVPYFKTMASTTENVAIYVWDQLQRIM 486
                   + NITD     K  I   ++    +N++P          N  I+ ++ +   M
Sbjct: 1396 NMINDINIQNITDKHVINKNIINYKINENKTENNIPLVNNKNKILVNNNIHTYNNIH--M 1453

Query: 487  EKPQLLHEVK 516
                 LHE K
Sbjct: 1454 TNINALHEKK 1463


>UniRef50_A3ZTI8 Cluster: 6-pyruvoyl tetrahydrobiopterin synthase;
           n=2; Planctomycetaceae|Rep: 6-pyruvoyl
           tetrahydrobiopterin synthase - Blastopirellula marina
           DSM 3645
          Length = 167

 Score = 32.7 bits (71), Expect = 6.7
 Identities = 27/77 (35%), Positives = 33/77 (42%)
 Frame = +1

Query: 160 IIRRETFSSAHRLHSPFLSDEENKKVYGKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNI 339
           I+RR  F + HRL+          K  GKC     HGHNYV    V        G V++ 
Sbjct: 13  IMRRIKFCAGHRLY----------KHGGKCEF--FHGHNYVADFYVTADEVDDVGRVIDF 60

Query: 340 TDLKKYIKTAILEPLDH 390
            DLK   K  + E  DH
Sbjct: 61  ADLKAKFKGWLDEHWDH 77


>UniRef50_A1KA79 Cluster: 6-pyruvoyltetrahydropterin synthase; n=17;
           Betaproteobacteria|Rep: 6-pyruvoyltetrahydropterin
           synthase - Azoarcus sp. (strain BH72)
          Length = 151

 Score = 32.7 bits (71), Expect = 6.7
 Identities = 16/47 (34%), Positives = 24/47 (51%), Gaps = 5/47 (10%)
 Frame = +1

Query: 265 HGHNYVVLVTVKGPV-----DPQTGMVMNITDLKKYIKTAILEPLDH 390
           HGH Y + VT+ G +      P  GMVM+  ++K+     I+   DH
Sbjct: 26  HGHRYAIEVTLSGEIIDAAGQPVNGMVMDFGEVKRLAAEHIVSVWDH 72


>UniRef50_Q190Y3 Cluster: Cytochrome C family protein precursor;
           n=2; Desulfitobacterium hafniense|Rep: Cytochrome C
           family protein precursor - Desulfitobacterium hafniense
           (strain DCB-2)
          Length = 353

 Score = 32.3 bits (70), Expect = 8.9
 Identities = 17/44 (38%), Positives = 24/44 (54%), Gaps = 1/44 (2%)
 Frame = +1

Query: 199 HSPFLSDEENKKVYG-KCNNPNGHGHNYVVLVTVKGPVDPQTGM 327
           HSP +  E N K YG  C + +G G N+V      G +DP+T +
Sbjct: 174 HSPGI--EHNSKDYGVSCESCHGPGGNHVTAANKAGTMDPKTAV 215


>UniRef50_Q9HHN6 Cluster: Vng6306c; n=2; Halobacteriaceae|Rep:
           Vng6306c - Halobacterium salinarium (Halobacterium
           halobium)
          Length = 150

 Score = 32.3 bits (70), Expect = 8.9
 Identities = 23/78 (29%), Positives = 38/78 (48%), Gaps = 1/78 (1%)
 Frame = +1

Query: 241 GKCNNPNGHGHNYVVLVTVKGPVDPQTGMVMNITDLKKYIKTAILEPLDHK-NLDNDVPY 417
           GKC+ P  HGHNY + V + G +  + G V++     K   TA++   DH+  L++  P 
Sbjct: 40  GKCSRP--HGHNYEISVEITGQLTDE-GWVVD-----KGTVTAVVSDWDHRFLLEDGDPL 91

Query: 418 FKTMASTTENVAIYVWDQ 471
                   +  A+ V +Q
Sbjct: 92  VDAFREAGDGDAVVVLEQ 109


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 557,487,135
Number of Sequences: 1657284
Number of extensions: 10955719
Number of successful extensions: 26469
Number of sequences better than 10.0: 88
Number of HSP's better than 10.0 without gapping: 25645
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 26427
length of database: 575,637,011
effective HSP length: 97
effective length of database: 414,880,463
effective search space used: 41902926763
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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