Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= bmov10m14
(582 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q8WRT0 Cluster: 3-dehydrecdysone 3b-reductase; n=1; Tri... 125 9e-28
UniRef50_A5E082 Cluster: GCY protein; n=4; Saccharomycetales|Rep... 113 3e-24
UniRef50_UPI00015B56A2 Cluster: PREDICTED: similar to GA10458-PA... 113 4e-24
UniRef50_A1UEC5 Cluster: 2,5-didehydrogluconate reductase; n=20;... 112 7e-24
UniRef50_UPI00015B56A3 Cluster: PREDICTED: similar to aldo-keto ... 107 1e-22
UniRef50_P14065 Cluster: Protein GCY; n=13; Saccharomycetales|Re... 107 2e-22
UniRef50_Q1VRG6 Cluster: YvgN; n=1; Psychroflexus torquis ATCC 7... 107 2e-22
UniRef50_A0JRJ6 Cluster: Aldo/keto reductase; n=2; Micrococcinea... 103 2e-21
UniRef50_UPI000023D0F1 Cluster: hypothetical protein FG03517.1; ... 103 3e-21
UniRef50_Q0CK00 Cluster: Predicted protein; n=1; Aspergillus ter... 102 5e-21
UniRef50_Q8K023 Cluster: Aldo-keto reductase family 1 member C18... 102 5e-21
UniRef50_P06632 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 102 7e-21
UniRef50_Q88TV9 Cluster: Oxidoreductase; n=4; Lactobacillus|Rep:... 100 2e-20
UniRef50_A3U9Y0 Cluster: Aldehyde reductase; n=5; Bacteroidetes|... 100 2e-20
UniRef50_Q9Y020 Cluster: 3-dehydroecdysone 3beta-reductase precu... 100 2e-20
UniRef50_Q8VC28 Cluster: Aldo-keto reductase family 1 member C13... 100 2e-20
UniRef50_A2QBD7 Cluster: Catalytic activity: an alcohol + NADP(+... 99 4e-20
UniRef50_P22045 Cluster: Probable reductase; n=101; cellular org... 99 4e-20
UniRef50_Q88SL1 Cluster: Oxidoreductase; n=51; Lactobacillales|R... 100 5e-20
UniRef50_Q68ST9 Cluster: Reductase AKOR2; n=2; Pleurotus djamor|... 97 2e-19
UniRef50_Q9HGY0 Cluster: Glycerol dehydrogenase; n=8; Saccharomy... 97 3e-19
UniRef50_Q16K66 Cluster: Aldo-keto reductase; n=2; Aedes aegypti... 97 4e-19
UniRef50_Q1U9L6 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 96 5e-19
UniRef50_A7CUW0 Cluster: 2,5-didehydrogluconate reductase; n=6; ... 96 5e-19
UniRef50_Q4P4P1 Cluster: Putative uncharacterized protein; n=1; ... 96 5e-19
UniRef50_Q83N50 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 96 6e-19
UniRef50_Q043M4 Cluster: Aldo/keto reductase of diketogulonate r... 96 6e-19
UniRef50_Q4PDR0 Cluster: Putative uncharacterized protein; n=1; ... 95 8e-19
UniRef50_Q8F1G4 Cluster: Aldehyde reductase; n=8; Bacteria|Rep: ... 95 1e-18
UniRef50_Q03TW0 Cluster: Aldo/keto reductase of diketogulonate r... 95 1e-18
UniRef50_Q10494 Cluster: Probable oxidoreductase C26F1.07; n=2; ... 95 1e-18
UniRef50_A7RRF6 Cluster: Predicted protein; n=2; Nematostella ve... 94 2e-18
UniRef50_Q927P9 Cluster: Lin2739 protein; n=12; Bacteria|Rep: Li... 93 3e-18
UniRef50_Q3CZS2 Cluster: Oxidoreductase, aldo/keto reductase fam... 93 3e-18
UniRef50_Q2U219 Cluster: Aldo/keto reductase family proteins; n=... 93 3e-18
UniRef50_Q8ZI40 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 93 3e-18
UniRef50_Q7N0E4 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 92 8e-18
UniRef50_A7SGW6 Cluster: Predicted protein; n=1; Nematostella ve... 92 8e-18
UniRef50_Q96UH3 Cluster: Aldehyde reductase; n=13; Pezizomycotin... 92 8e-18
UniRef50_Q2UGR1 Cluster: Aldo/keto reductase family proteins; n=... 92 8e-18
UniRef50_Q9ZBW7 Cluster: Putative oxidoreductase; n=2; Actinomyc... 91 1e-17
UniRef50_Q890A0 Cluster: Oxidoreductase; n=6; Lactobacillales|Re... 91 1e-17
UniRef50_P15121 Cluster: Aldose reductase; n=72; Eumetazoa|Rep: ... 91 1e-17
UniRef50_Q0VGY1 Cluster: 3-alpha-hydroxysteroid dehydrogenase; n... 91 2e-17
UniRef50_Q8Y463 Cluster: Lmo2592 protein; n=40; Bacteria|Rep: Lm... 91 2e-17
UniRef50_A6W8E7 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 91 2e-17
UniRef50_Q5FLI5 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: ... 90 3e-17
UniRef50_A7BA05 Cluster: Putative uncharacterized protein; n=1; ... 90 3e-17
UniRef50_Q5KI95 Cluster: Aldo-keto reductase, putative; n=14; Di... 90 3e-17
UniRef50_P14550 Cluster: Alcohol dehydrogenase [NADP+]; n=44; Bi... 90 3e-17
UniRef50_P45376 Cluster: Aldose reductase; n=21; Bilateria|Rep: ... 90 4e-17
UniRef50_A2R6Z3 Cluster: Catalytic activity: an alcohol + NADP(+... 89 5e-17
UniRef50_P27800 Cluster: Aldehyde reductase 1; n=18; root|Rep: A... 89 7e-17
UniRef50_Q8EVS8 Cluster: Oxidoreductase; n=1; Mycoplasma penetra... 89 9e-17
UniRef50_Q6F7K7 Cluster: 2,5-diketo-D-gluconate reductase; n=20;... 88 2e-16
UniRef50_Q41E86 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 88 2e-16
UniRef50_Q4Q5N9 Cluster: Prostaglandin f synthase, putative; n=7... 88 2e-16
UniRef50_UPI00015B4B22 Cluster: PREDICTED: similar to GA15457-PA... 87 2e-16
UniRef50_A5ZYE6 Cluster: Putative uncharacterized protein; n=1; ... 87 2e-16
UniRef50_P51857 Cluster: 3-oxo-5-beta-steroid 4-dehydrogenase (E... 87 2e-16
UniRef50_Q5BKE9 Cluster: LOC594893 protein; n=5; Xenopus tropica... 87 3e-16
UniRef50_A2UAH0 Cluster: Aldo/keto reductase; n=1; Bacillus coag... 87 3e-16
UniRef50_Q8ET73 Cluster: 2,5-diketo-D-gluconate reductase; n=12;... 87 4e-16
UniRef50_Q7JVH6 Cluster: LD24696p; n=2; Sophophora|Rep: LD24696p... 87 4e-16
UniRef50_Q02198 Cluster: Morphine 6-dehydrogenase; n=5; Bacteria... 87 4e-16
UniRef50_Q7WSY4 Cluster: Putative aldo-keto reductase; n=1; Prop... 86 5e-16
UniRef50_Q05KR9 Cluster: Benzil reductase; n=5; Bacillales|Rep: ... 86 5e-16
UniRef50_A6VNW9 Cluster: Aldo/keto reductase precursor; n=1; Act... 86 7e-16
UniRef50_P15339 Cluster: 2,5-diketo-D-gluconic acid reductase B;... 86 7e-16
UniRef50_Q9X0A2 Cluster: Oxidoreductase, aldo/keto reductase fam... 85 9e-16
UniRef50_Q6CFG7 Cluster: Yarrowia lipolytica chromosome B of str... 85 1e-15
UniRef50_Q7VHE1 Cluster: Putative uncharacterized protein; n=1; ... 85 2e-15
UniRef50_Q7VG53 Cluster: Aldo-keto reductase; n=28; Bacteria|Rep... 85 2e-15
UniRef50_Q9VHX4 Cluster: CG2767-PA; n=4; Endopterygota|Rep: CG27... 85 2e-15
UniRef50_Q17G72 Cluster: Aldo-keto reductase; n=9; Endopterygota... 85 2e-15
UniRef50_Q5FK98 Cluster: Oxidoreductase; n=8; Lactobacillales|Re... 84 2e-15
UniRef50_Q2S340 Cluster: Aldehyde reductase; n=10; Bacteria|Rep:... 84 2e-15
UniRef50_O13848 Cluster: NADH/NADPH dependent indole-3-acetaldeh... 84 2e-15
UniRef50_A2QVE5 Cluster: Similarity: shows similarity to several... 84 2e-15
UniRef50_A2QL02 Cluster: Putative frameshift; n=1; Aspergillus n... 84 2e-15
UniRef50_A2RMU6 Cluster: Oxidoreductase, aldo/keto reductase fam... 84 3e-15
UniRef50_Q968S3 Cluster: Aldoketoreductase-like protein; n=1; Or... 84 3e-15
UniRef50_Q9NAI5 Cluster: Putative uncharacterized protein; n=3; ... 83 4e-15
UniRef50_Q03U37 Cluster: Aldo/keto reductase of diketogulonate r... 83 5e-15
UniRef50_A7CWF9 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: ... 83 5e-15
UniRef50_A7ALH6 Cluster: Putative uncharacterized protein; n=1; ... 83 5e-15
UniRef50_Q23320 Cluster: Putative uncharacterized protein; n=4; ... 83 5e-15
UniRef50_Q8EVT8 Cluster: Oxidoreductase-aldo/keto reductase fami... 83 6e-15
UniRef50_A0AWM8 Cluster: Aldo/keto reductase; n=4; Actinomycetal... 83 6e-15
UniRef50_A7BES9 Cluster: Putative uncharacterized protein; n=1; ... 82 8e-15
UniRef50_Q6TY50 Cluster: Reductase 2; n=10; Magnoliophyta|Rep: R... 82 8e-15
UniRef50_Q7QK25 Cluster: ENSANGP00000019775; n=2; Anopheles gamb... 82 8e-15
UniRef50_UPI0000499B0E Cluster: oxidoreductase, aldo/keto reduct... 81 1e-14
UniRef50_Q22352 Cluster: Putative uncharacterized protein T08H10... 81 1e-14
UniRef50_A7EW94 Cluster: Putative uncharacterized protein; n=1; ... 81 1e-14
UniRef50_Q28P63 Cluster: Aldo/keto reductase; n=4; Rhodobacterac... 81 2e-14
UniRef50_Q55FL3 Cluster: Aldo-keto reductase; n=2; Dictyostelium... 81 2e-14
UniRef50_Q5XJM7 Cluster: Zgc:101765; n=5; Eumetazoa|Rep: Zgc:101... 81 2e-14
UniRef50_Q03PG5 Cluster: Aldo/keto reductase of diketogulonate r... 81 2e-14
UniRef50_Q6NII7 Cluster: Putative oxidoreductase; n=2; Corynebac... 80 3e-14
UniRef50_Q5FK99 Cluster: Oxidoreductase aldo-keto reductase fami... 80 3e-14
UniRef50_Q7ZA52 Cluster: Aldose reductase; n=6; Pezizomycotina|R... 80 3e-14
UniRef50_UPI00015B40FA Cluster: PREDICTED: similar to CG2767-PA;... 80 4e-14
UniRef50_A0JRJ3 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 80 4e-14
UniRef50_Q235V6 Cluster: Oxidoreductase, aldo/keto reductase fam... 80 4e-14
UniRef50_Q4JX70 Cluster: Putative oxidoreductase; n=1; Corynebac... 79 6e-14
UniRef50_Q01HB5 Cluster: OSIGBa0136O08-OSIGBa0153H12.9 protein; ... 79 6e-14
UniRef50_Q7PCV3 Cluster: ENSANGP00000031808; n=9; Endopterygota|... 79 6e-14
UniRef50_A7SIT3 Cluster: Predicted protein; n=1; Nematostella ve... 79 6e-14
UniRef50_UPI0000519CC2 Cluster: PREDICTED: similar to CG2767-PA;... 79 8e-14
UniRef50_Q568D7 Cluster: Zgc:110366; n=7; Euteleostomi|Rep: Zgc:... 79 8e-14
UniRef50_A6ESC0 Cluster: ARA1; n=1; unidentified eubacterium SCB... 79 8e-14
UniRef50_Q5HR31 Cluster: Oxidoreductase, aldo/keto reductase fam... 79 1e-13
UniRef50_Q5K8C5 Cluster: Aldo-keto reductase, putative; n=1; Fil... 79 1e-13
UniRef50_UPI0000E4A7CE Cluster: PREDICTED: similar to LOC553452 ... 78 1e-13
UniRef50_Q9A2X8 Cluster: Oxidoreductase, aldo/keto reductase fam... 78 1e-13
UniRef50_Q0SFM4 Cluster: Probable 2,5-didehydrogluconate reducta... 78 1e-13
UniRef50_Q4DJ59 Cluster: Aldo/keto reductase, putative; n=2; Try... 78 1e-13
UniRef50_Q0CLQ2 Cluster: Putative uncharacterized protein; n=1; ... 78 1e-13
UniRef50_A6RMS0 Cluster: Putative uncharacterized protein; n=1; ... 78 1e-13
UniRef50_UPI0000588153 Cluster: PREDICTED: hypothetical protein;... 78 2e-13
UniRef50_Q89JN4 Cluster: Oxidoreductase; n=8; Rhizobiales|Rep: O... 78 2e-13
UniRef50_Q1IN88 Cluster: Aldehyde reductase; n=5; Bacteria|Rep: ... 78 2e-13
UniRef50_A3VHZ9 Cluster: Oxidoreductase; n=1; Rhodobacterales ba... 78 2e-13
UniRef50_A3JU52 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 78 2e-13
UniRef50_Q838E0 Cluster: Oxidoreductase, aldo/keto reductase fam... 77 2e-13
UniRef50_Q4V008 Cluster: Oxidoreductase; n=4; Proteobacteria|Rep... 77 2e-13
UniRef50_Q17DN0 Cluster: Aldo-keto reductase; n=5; Culicidae|Rep... 77 2e-13
UniRef50_Q929C8 Cluster: Lin2349 protein; n=12; Listeria|Rep: Li... 77 3e-13
UniRef50_A4FEB9 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 77 3e-13
UniRef50_A7RUA2 Cluster: Predicted protein; n=1; Nematostella ve... 77 3e-13
UniRef50_A2EHN6 Cluster: Oxidoreductase, aldo/keto reductase fam... 77 3e-13
UniRef50_A6RKL9 Cluster: Putative uncharacterized protein; n=3; ... 77 3e-13
UniRef50_A4RQH8 Cluster: Predicted protein; n=2; Ostreococcus|Re... 77 4e-13
UniRef50_Q7PLK6 Cluster: CG40064-PA; n=1; Drosophila melanogaste... 77 4e-13
UniRef50_Q5KD52 Cluster: Oxidoreductase, putative; n=1; Filobasi... 77 4e-13
UniRef50_A3LTU8 Cluster: D-arabinose dehydrogenase; n=5; Sacchar... 77 4e-13
UniRef50_Q8G7K9 Cluster: Dehydrogenase or reductase protein; n=4... 76 5e-13
UniRef50_Q5FKI1 Cluster: Reductase-dehydrogenase; n=1; Lactobaci... 76 5e-13
UniRef50_A3UJS6 Cluster: Oxidoreductase; n=3; Alphaproteobacteri... 76 5e-13
UniRef50_Q2V420 Cluster: Uncharacterized protein At2g37770.1; n=... 76 5e-13
UniRef50_Q0PGJ6 Cluster: Aldo-keto reductase; n=32; Magnoliophyt... 76 5e-13
UniRef50_Q54B70 Cluster: Aldehyde reductase; n=2; Dictyostelium ... 76 5e-13
UniRef50_UPI0000498F1F Cluster: oxidoreductase, aldo/keto reduct... 76 7e-13
UniRef50_UPI000065D0BD Cluster: Homolog of Homo sapiens "AKR1B1 ... 76 7e-13
UniRef50_Q8EUH6 Cluster: Oxidoreductase; n=1; Mycoplasma penetra... 76 7e-13
UniRef50_Q5TNP1 Cluster: ENSANGP00000029046; n=2; Culicidae|Rep:... 76 7e-13
UniRef50_Q5UX52 Cluster: Oxidoreductase aldo/keto reductase fami... 76 7e-13
UniRef50_Q8CI22 Cluster: 2310005E10Rik protein; n=30; Tetrapoda|... 75 9e-13
UniRef50_Q6RZX1 Cluster: Gld1; n=22; Pezizomycotina|Rep: Gld1 - ... 75 9e-13
UniRef50_Q5B5R6 Cluster: Putative uncharacterized protein; n=1; ... 75 9e-13
UniRef50_Q4PAT5 Cluster: Putative uncharacterized protein; n=1; ... 75 9e-13
UniRef50_Q4PHK0 Cluster: Putative uncharacterized protein; n=1; ... 64 9e-13
UniRef50_Q96JD6 Cluster: Aldo-keto reductase family 1 member C-l... 72 9e-13
UniRef50_Q96JD6-2 Cluster: Isoform 2 of Q96JD6 ; n=4; Catarrhini... 72 9e-13
UniRef50_A4YQ04 Cluster: 2,5-diketo-D-gluconate reductase B; n=1... 75 1e-12
UniRef50_Q7PM68 Cluster: ENSANGP00000014386; n=1; Anopheles gamb... 75 1e-12
UniRef50_Q24C22 Cluster: Oxidoreductase, aldo/keto reductase fam... 75 1e-12
UniRef50_Q9P6D3 Cluster: Related to aldo-keto reductase YPR1; n=... 75 1e-12
UniRef50_Q76L37 Cluster: Conjugated polyketone reductase C1; n=3... 75 2e-12
UniRef50_P38115 Cluster: D-arabinose dehydrogenase [NAD(P)+] hea... 75 2e-12
UniRef50_Q7NB44 Cluster: ARA1; n=3; Firmicutes|Rep: ARA1 - Mycop... 74 2e-12
UniRef50_A1CAM7 Cluster: Aldo-keto reductase, putative; n=9; Dik... 74 2e-12
UniRef50_UPI00006CD296 Cluster: oxidoreductase, aldo/keto reduct... 74 3e-12
UniRef50_Q9VTL0 Cluster: CG6083-PA; n=4; Diptera|Rep: CG6083-PA ... 74 3e-12
UniRef50_Q5BLA6 Cluster: Zgc:110782; n=2; Danio rerio|Rep: Zgc:1... 73 4e-12
UniRef50_Q2BBN7 Cluster: YvgN; n=1; Bacillus sp. NRRL B-14911|Re... 73 4e-12
UniRef50_Q572D2 Cluster: Aldo-keto reductase, putative; n=1; Phy... 73 4e-12
UniRef50_Q01J82 Cluster: OSIGBa0152K17.5 protein; n=28; Magnolio... 73 4e-12
UniRef50_Q8SSK6 Cluster: ALDOSE REDUCTASE; n=1; Encephalitozoon ... 73 4e-12
UniRef50_A2QB88 Cluster: Contig An01c0460, complete genome. prec... 73 4e-12
UniRef50_UPI0000E45E29 Cluster: PREDICTED: similar to aldose red... 73 5e-12
UniRef50_Q15NA5 Cluster: Aldo/keto reductase; n=2; Gammaproteoba... 73 5e-12
UniRef50_Q6CWB9 Cluster: Similarities with sp|Q12458 Saccharomyc... 73 5e-12
UniRef50_UPI00015B5BD7 Cluster: PREDICTED: similar to aldo-keto ... 73 7e-12
UniRef50_Q14LU6 Cluster: Putative aldo/keto reductase oxidoreduc... 73 7e-12
UniRef50_A6LZ55 Cluster: 2,5-didehydrogluconate reductase; n=1; ... 73 7e-12
UniRef50_Q4Q973 Cluster: Aldo/keto reductase, putative; n=3; Lei... 73 7e-12
UniRef50_Q6CEJ0 Cluster: Yarrowia lipolytica chromosome B of str... 73 7e-12
UniRef50_A6WDZ5 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:... 72 9e-12
UniRef50_A5KSS3 Cluster: Aldehyde reductase; n=1; candidate divi... 72 9e-12
UniRef50_A3VRL4 Cluster: Putative uncharacterized protein; n=1; ... 72 9e-12
UniRef50_Q2LZ66 Cluster: GA19341-PA; n=2; Endopterygota|Rep: GA1... 72 9e-12
UniRef50_A2EYY6 Cluster: Oxidoreductase, aldo/keto reductase fam... 72 9e-12
UniRef50_Q8ZH36 Cluster: 2,5-diketo-D-gluconic acid reductase B;... 72 9e-12
UniRef50_Q6U5V3 Cluster: Putative uncharacterized protein; n=1; ... 72 1e-11
UniRef50_Q0IBY6 Cluster: Alcohol dehydrogenase; n=2; Chroococcal... 72 1e-11
UniRef50_A6NPD6 Cluster: Putative uncharacterized protein; n=3; ... 72 1e-11
UniRef50_A5PDA8 Cluster: Putative oxidoreductase protein; n=1; E... 72 1e-11
UniRef50_Q5KKZ8 Cluster: Aldo-keto reductase, putative; n=2; Fil... 72 1e-11
UniRef50_UPI00015B4912 Cluster: PREDICTED: similar to aldo-keto ... 71 2e-11
UniRef50_Q4P1G1 Cluster: Putative uncharacterized protein; n=1; ... 71 2e-11
UniRef50_Q979I4 Cluster: Aldo / keto reductase; n=3; Archaea|Rep... 71 2e-11
UniRef50_Q5FT75 Cluster: Putative 2,5-diketo-D-gluconic acid red... 71 2e-11
UniRef50_Q68A33 Cluster: Aldo-keto reductase 1a; n=1; Ciona inte... 71 2e-11
UniRef50_P23901 Cluster: Aldose reductase; n=9; Poaceae|Rep: Ald... 71 2e-11
UniRef50_UPI00006CCCD7 Cluster: oxidoreductase, aldo/keto reduct... 71 3e-11
UniRef50_Q11DV1 Cluster: Aldo/keto reductase; n=10; Alphaproteob... 71 3e-11
UniRef50_Q03XK0 Cluster: Aldo/keto reductase of diketogulonate r... 71 3e-11
UniRef50_A6QXT4 Cluster: Predicted protein; n=1; Ajellomyces cap... 71 3e-11
UniRef50_Q5V663 Cluster: Aldehyde reductase; n=6; Halobacteriace... 71 3e-11
UniRef50_UPI000155CAC7 Cluster: PREDICTED: hypothetical protein;... 70 3e-11
UniRef50_Q11BF8 Cluster: Aldo/keto reductase; n=12; Bacteria|Rep... 70 3e-11
UniRef50_Q41399 Cluster: Chalcone reductase; n=4; eudicotyledons... 70 3e-11
UniRef50_A2FPE2 Cluster: Oxidoreductase, aldo/keto reductase fam... 70 3e-11
UniRef50_Q4WI64 Cluster: Aldehyde reductase, putative; n=22; Pez... 70 3e-11
UniRef50_A7TLC4 Cluster: Putative uncharacterized protein; n=1; ... 70 3e-11
UniRef50_Q97UV9 Cluster: Oxidoreductase; n=1; Sulfolobus solfata... 70 3e-11
UniRef50_UPI00006CA3CB Cluster: oxidoreductase, aldo/keto reduct... 70 5e-11
UniRef50_Q1RFP0 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 70 5e-11
UniRef50_Q6C2L0 Cluster: Yarrowia lipolytica chromosome F of str... 70 5e-11
UniRef50_P26690 Cluster: NAD(P)H-dependent 6'-deoxychalcone synt... 70 5e-11
UniRef50_A7PNI3 Cluster: Chromosome chr1 scaffold_22, whole geno... 69 6e-11
UniRef50_Q4WUF7 Cluster: Aldo-keto reductase, putative; n=3; Pez... 69 6e-11
UniRef50_Q11B35 Cluster: Aldo/keto reductase; n=1; Mesorhizobium... 69 8e-11
UniRef50_Q9FJK0 Cluster: Aldose reductase-like protein; n=3; cor... 69 8e-11
UniRef50_Q927E1 Cluster: Lin2848 protein; n=13; Listeria|Rep: Li... 69 1e-10
UniRef50_P70883 Cluster: AkrI; n=1; Butyrivibrio fibrisolvens|Re... 69 1e-10
UniRef50_A3C1Z7 Cluster: Putative uncharacterized protein; n=2; ... 69 1e-10
UniRef50_A7D7K7 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 69 1e-10
UniRef50_Q9X265 Cluster: Oxidoreductase, aldo/keto reductase fam... 68 1e-10
UniRef50_Q5NLW3 Cluster: Putative oxidoreductase; n=1; Zymomonas... 68 1e-10
UniRef50_A1RB46 Cluster: 2,5-diketo-D-gluconate reductase; n=1; ... 68 1e-10
UniRef50_Q54NR2 Cluster: Aldo-keto reductase; n=3; Dictyostelium... 68 1e-10
UniRef50_P91997 Cluster: Putative uncharacterized protein; n=4; ... 68 1e-10
UniRef50_Q5T2L2 Cluster: Aldo-keto reductase family 1 member C-l... 68 1e-10
UniRef50_Q16CS5 Cluster: 2,5-diketo-D-gluconic acid reductase B,... 68 2e-10
UniRef50_A0JX62 Cluster: 2,5-didehydrogluconate reductase; n=9; ... 68 2e-10
UniRef50_Q21274 Cluster: Putative uncharacterized protein; n=1; ... 68 2e-10
UniRef50_Q17DN1 Cluster: Aldo-keto reductase; n=1; Aedes aegypti... 68 2e-10
UniRef50_Q75E75 Cluster: ABL209Cp; n=1; Eremothecium gossypii|Re... 68 2e-10
UniRef50_Q1M4Z6 Cluster: Putative aldo-keto reductase/oxidase; n... 67 2e-10
UniRef50_A0L1A2 Cluster: Aldo/keto reductase; n=8; Gammaproteoba... 67 2e-10
UniRef50_Q7QVQ9 Cluster: GLP_302_44328_45269; n=1; Giardia lambl... 67 2e-10
UniRef50_Q4FY75 Cluster: Aldo-keto reductase-like protein; n=5; ... 67 3e-10
UniRef50_UPI0000D9A956 Cluster: PREDICTED: similar to aldo-keto ... 66 4e-10
UniRef50_Q9HM42 Cluster: Alcohol dehydrogenase related protein; ... 66 4e-10
UniRef50_Q09632 Cluster: Probable oxidoreductase ZK1290.5; n=2; ... 66 4e-10
UniRef50_A7D6Q0 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 66 6e-10
UniRef50_P38715 Cluster: NADPH-dependent aldose reductase GRE3; ... 66 6e-10
UniRef50_Q7ZWA4 Cluster: Zgc:56622; n=6; cellular organisms|Rep:... 66 8e-10
UniRef50_Q2H7A8 Cluster: Putative uncharacterized protein; n=1; ... 65 1e-09
UniRef50_UPI0000DB6EE9 Cluster: PREDICTED: similar to C35D10.6; ... 65 1e-09
UniRef50_Q9U2J5 Cluster: Putative uncharacterized protein; n=2; ... 65 1e-09
UniRef50_Q76L36 Cluster: Conjugated polyketone reductase C2; n=1... 65 1e-09
UniRef50_Q2CAL9 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 64 2e-09
UniRef50_Q9ZUJ6 Cluster: T2K10.1 protein; n=16; core eudicotyled... 64 2e-09
UniRef50_P28475 Cluster: NADP-dependent D-sorbitol-6-phosphate d... 64 2e-09
UniRef50_Q1DLF1 Cluster: Putative uncharacterized protein; n=1; ... 64 3e-09
UniRef50_A5VK30 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 63 4e-09
UniRef50_Q5UYI9 Cluster: Oxidoreductase; n=1; Haloarcula marismo... 63 4e-09
UniRef50_Q5KCN9 Cluster: Putative uncharacterized protein; n=1; ... 63 5e-09
UniRef50_Q4PE96 Cluster: Putative uncharacterized protein; n=1; ... 63 5e-09
UniRef50_Q5V398 Cluster: Oxidoreductase aldo/keto reductase fami... 63 5e-09
UniRef50_Q18483 Cluster: Putative uncharacterized protein; n=2; ... 62 7e-09
UniRef50_A5DRJ6 Cluster: Putative uncharacterized protein; n=4; ... 62 7e-09
UniRef50_Q1Q8W8 Cluster: Aldo/keto reductase; n=1; Psychrobacter... 62 9e-09
UniRef50_Q61U89 Cluster: Putative uncharacterized protein CBG054... 62 9e-09
UniRef50_Q4WP69 Cluster: Aldehyde reductase, putative; n=1; Aspe... 62 9e-09
UniRef50_Q7G764 Cluster: Probable NAD(P)H-dependent oxidoreducta... 62 9e-09
UniRef50_A7LSN6 Cluster: Putative uncharacterized protein; n=3; ... 62 1e-08
UniRef50_Q9P734 Cluster: Related to 2, 5-diketo-D-gluconic acid ... 62 1e-08
UniRef50_A3LWP0 Cluster: Aldo/keto reductase; n=7; Saccharomycet... 62 1e-08
UniRef50_UPI000023DF27 Cluster: hypothetical protein FG07276.1; ... 61 2e-08
UniRef50_Q14LA8 Cluster: Putative aldo/keto reductase oxidoreduc... 60 4e-08
UniRef50_Q03X85 Cluster: Aldo/keto reductase of diketogulonate r... 60 4e-08
UniRef50_A6PR52 Cluster: Aldo/keto reductase; n=1; Victivallis v... 60 4e-08
UniRef50_Q5V1M9 Cluster: Oxidoreductase aldo/keto reductase fami... 60 4e-08
UniRef50_A3T261 Cluster: Putative uncharacterized protein; n=1; ... 60 5e-08
UniRef50_Q9C1X5 Cluster: Xylose and arabinose reductase; n=1; Sc... 60 5e-08
UniRef50_Q5KKC5 Cluster: Putative uncharacterized protein; n=2; ... 60 5e-08
UniRef50_Q4JCC1 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 59 7e-08
UniRef50_A1S0T5 Cluster: Aldo/keto reductase; n=2; Thermoprotei|... 59 7e-08
UniRef50_Q64UK5 Cluster: Aldo/keto reductase family oxidoreducta... 58 1e-07
UniRef50_A6SJ74 Cluster: Putative uncharacterized protein; n=1; ... 58 1e-07
UniRef50_Q7G765 Cluster: Probable NAD(P)H-dependent oxidoreducta... 58 1e-07
UniRef50_A2G4I3 Cluster: Oxidoreductase, aldo/keto reductase fam... 58 2e-07
UniRef50_A3H9Y8 Cluster: Aldo/keto reductase; n=2; Caldivirga ma... 58 2e-07
UniRef50_Q8J0K1 Cluster: 4-dihydromethyltrisporate dehydrogenase... 58 2e-07
UniRef50_O14088 Cluster: Xylose and arabinose reductase; n=1; Sc... 58 2e-07
UniRef50_Q3E9M9 Cluster: Uncharacterized protein At5g01670.2; n=... 43 3e-07
UniRef50_Q1YPE5 Cluster: Aldehyde reductase; n=7; Bacteria|Rep: ... 57 3e-07
UniRef50_Q2NEM6 Cluster: Putative oxidoreductase; n=1; Methanosp... 57 3e-07
UniRef50_A6LWU9 Cluster: Aldo/keto reductase; n=3; Clostridium|R... 57 3e-07
UniRef50_Q4Q5X1 Cluster: Aldehyde reductase, putative; n=75; cel... 56 5e-07
UniRef50_P91021 Cluster: Putative uncharacterized protein; n=1; ... 56 5e-07
UniRef50_Q59Z55 Cluster: Potential aldo/keto reductase; n=6; Sac... 56 5e-07
UniRef50_Q5FHT2 Cluster: Aldehyde reductase; n=4; Lactobacillus|... 56 6e-07
UniRef50_Q1PV10 Cluster: Putative uncharacterized protein; n=1; ... 56 6e-07
UniRef50_A4R217 Cluster: Putative uncharacterized protein; n=1; ... 56 6e-07
UniRef50_Q9V2P1 Cluster: Myo-inositol degradation; n=5; Archaea|... 56 6e-07
UniRef50_Q0GU15 Cluster: ORF28; n=3; Bacteria|Rep: ORF28 - Lacto... 56 8e-07
UniRef50_Q97U17 Cluster: Oxidoreductase, aldo/keto reductase fam... 56 8e-07
UniRef50_A6SUJ2 Cluster: Uncharacterized conserved protein; n=2;... 55 1e-06
UniRef50_Q17568 Cluster: Putative uncharacterized protein; n=1; ... 55 1e-06
UniRef50_Q5B034 Cluster: Putative uncharacterized protein; n=1; ... 55 1e-06
UniRef50_Q5V6N9 Cluster: Alcohol dehydrogenase; n=2; Halobacteri... 55 1e-06
UniRef50_Q07551 Cluster: NADPH-dependent alpha-keto amide reduct... 55 1e-06
UniRef50_P76234 Cluster: Uncharacterized protein yeaE; n=39; Bac... 54 2e-06
UniRef50_A5UNN5 Cluster: Predicted oxidoreductase, aldo/keto red... 54 3e-06
UniRef50_P46905 Cluster: Uncharacterized oxidoreductase yccK; n=... 54 3e-06
UniRef50_Q8DK16 Cluster: Tlr1054 protein; n=6; Cyanobacteria|Rep... 53 4e-06
UniRef50_Q97V56 Cluster: Dehydrogenase; n=8; Thermoprotei|Rep: D... 53 4e-06
UniRef50_Q8PN61 Cluster: Oxidoreductase; n=5; Proteobacteria|Rep... 52 8e-06
UniRef50_Q7D3N9 Cluster: AGR_pAT_274p; n=3; Proteobacteria|Rep: ... 52 8e-06
UniRef50_A1D4E3 Cluster: D-xylose reductase (Xyl1), putative; n=... 52 8e-06
UniRef50_UPI0000D56CE5 Cluster: PREDICTED: similar to CG6084-PA,... 52 1e-05
UniRef50_Q1FGT1 Cluster: Aldo/keto reductase:4Fe-4S ferredoxin, ... 52 1e-05
UniRef50_Q1EZH4 Cluster: Aldo/keto reductase:4Fe-4S ferredoxin, ... 52 1e-05
UniRef50_Q03BE0 Cluster: Aldo/keto reductase family enzyme; n=5;... 52 1e-05
UniRef50_Q7XY49 Cluster: Mannose 6-phosphate reductase; n=1; Gri... 52 1e-05
UniRef50_Q6WGK4 Cluster: Aldose reductase; n=1; Pristionchus pac... 52 1e-05
UniRef50_Q59ZT1 Cluster: Putative uncharacterized protein; n=1; ... 52 1e-05
UniRef50_Q6L139 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 52 1e-05
UniRef50_A7D761 Cluster: Aldo/keto reductase; n=2; Halobacteriac... 52 1e-05
UniRef50_A1RJL6 Cluster: Aldo/keto reductase; n=37; Bacteria|Rep... 52 1e-05
UniRef50_Q03I00 Cluster: Aryl-alcohol dehydrogenase related enzy... 51 2e-05
UniRef50_UPI000038E317 Cluster: hypothetical protein Faci_030017... 51 2e-05
UniRef50_A7D6I8 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 51 2e-05
UniRef50_P47137 Cluster: Probable oxidoreductase YJR096W; n=8; S... 51 2e-05
UniRef50_A7HER9 Cluster: Aldo/keto reductase; n=2; Anaeromyxobac... 50 3e-05
UniRef50_Q8ZU65 Cluster: Aldo-keto reductase, putative; n=4; The... 50 3e-05
UniRef50_UPI00005F9591 Cluster: COG0656: Aldo/keto reductases, r... 50 4e-05
UniRef50_Q55493 Cluster: Auxin-induced protein; n=2; Bacteria|Re... 50 4e-05
UniRef50_Q7R2T6 Cluster: GLP_291_56367_57278; n=1; Giardia lambl... 50 5e-05
UniRef50_A3DNU7 Cluster: Aldo/keto reductase; n=3; Desulfurococc... 50 5e-05
UniRef50_P82125 Cluster: 1,5-anhydro-D-fructose reductase; n=1; ... 49 7e-05
UniRef50_Q5V161 Cluster: Aldo/keto reductase; n=2; Halobacteriac... 38 8e-05
UniRef50_Q3AEN5 Cluster: Oxidoreductase, aldo/keto reductase fam... 49 9e-05
UniRef50_A0GAJ5 Cluster: Aldo/keto reductase precursor; n=9; Pro... 49 9e-05
UniRef50_Q98EU0 Cluster: Oxidoreductase; MocA; n=27; Bacteria|Re... 48 1e-04
UniRef50_A3LSR5 Cluster: D-threo-aldose 1-dehydrogenase; n=5; Sa... 48 1e-04
UniRef50_Q2J7H2 Cluster: Aldo/keto reductase; n=16; Bacteria|Rep... 48 2e-04
UniRef50_Q4J031 Cluster: Aldo/keto reductase precursor; n=2; Pse... 48 2e-04
UniRef50_Q08P32 Cluster: Aldo/keto reductase; n=3; Proteobacteri... 48 2e-04
UniRef50_P77735 Cluster: Uncharacterized oxidoreductase yajO; n=... 48 2e-04
UniRef50_Q40648 Cluster: Probable voltage-gated potassium channe... 48 2e-04
UniRef50_Q64W37 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 48 2e-04
UniRef50_A7DBQ3 Cluster: Aldo/keto reductase precursor; n=2; Met... 48 2e-04
UniRef50_A5VEK4 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:... 48 2e-04
UniRef50_A5CYR4 Cluster: Predicted oxidoreductases; n=2; Clostri... 48 2e-04
UniRef50_A4E7S8 Cluster: Putative uncharacterized protein; n=1; ... 48 2e-04
UniRef50_Q39151 Cluster: K+ channel protein; n=29; cellular orga... 48 2e-04
UniRef50_P73573 Cluster: Sll0867 protein; n=15; Bacteria|Rep: Sl... 47 3e-04
UniRef50_Q8TTK4 Cluster: Aldo/keto reductase; n=28; cellular org... 47 3e-04
UniRef50_Q983C8 Cluster: Oxido-reductase, and dehydratase; MocA;... 47 4e-04
UniRef50_A3WP89 Cluster: Aldo/keto reductase; n=1; Idiomarina ba... 47 4e-04
UniRef50_Q8Y5Q1 Cluster: Lmo2005 protein; n=34; cellular organis... 46 5e-04
UniRef50_A1ZSV4 Cluster: Oxidoreductase, aldo/keto reductase fam... 46 5e-04
UniRef50_Q9USV2 Cluster: Xylose and arabinose reductase; n=2; Sc... 46 5e-04
UniRef50_Q4TC86 Cluster: Chromosome undetermined SCAF7044, whole... 46 7e-04
UniRef50_Q8UIN0 Cluster: Oxidoreductase; n=3; Alphaproteobacteri... 46 7e-04
UniRef50_Q21EY6 Cluster: Aldo/keto reductase; n=1; Saccharophagu... 46 7e-04
UniRef50_Q6L0T3 Cluster: Oxidoreductase; n=2; Thermoplasmatales|... 46 7e-04
UniRef50_Q2NGB6 Cluster: Predicted oxidoreductase; n=1; Methanos... 46 7e-04
UniRef50_A5BF24 Cluster: Putative uncharacterized protein; n=1; ... 46 9e-04
UniRef50_Q7Q0Y6 Cluster: ENSANGP00000006086; n=7; Coelomata|Rep:... 46 9e-04
UniRef50_A7RXR1 Cluster: Predicted protein; n=3; Eumetazoa|Rep: ... 46 9e-04
UniRef50_Q14722 Cluster: Voltage-gated potassium channel subunit... 46 9e-04
UniRef50_Q8EVP7 Cluster: Putative oxidoreductase; n=3; Bacteria|... 45 0.001
UniRef50_Q1H0C2 Cluster: Twin-arginine translocation pathway sig... 45 0.001
UniRef50_Q7NH41 Cluster: Gll2696 protein; n=1; Gloeobacter viola... 45 0.002
UniRef50_A7GIW7 Cluster: Oxidoreductase, aldo/keto reductase fam... 45 0.002
UniRef50_A5AD50 Cluster: Putative uncharacterized protein; n=3; ... 45 0.002
UniRef50_A4IJ00 Cluster: LOC548351 protein; n=1; Xenopus tropica... 44 0.002
UniRef50_A0LHW7 Cluster: Aldo/keto reductase precursor; n=1; Syn... 44 0.002
UniRef50_A0DXM3 Cluster: Chromosome undetermined scaffold_69, wh... 44 0.002
UniRef50_A1DD54 Cluster: Aldo/keto reductase; n=3; Trichocomacea... 44 0.002
UniRef50_Q7NK63 Cluster: Gll1617 protein; n=1; Gloeobacter viola... 44 0.003
UniRef50_Q391C9 Cluster: Aldo/keto reductase; n=10; Proteobacter... 44 0.003
UniRef50_A6BIJ0 Cluster: Putative uncharacterized protein; n=1; ... 44 0.003
UniRef50_Q013C5 Cluster: Glycerol dehydrogenase, putative; n=2; ... 44 0.003
UniRef50_A3H9H5 Cluster: Aldo/keto reductase; n=2; Archaea|Rep: ... 44 0.003
UniRef50_A7P424 Cluster: Chromosome chr1 scaffold_5, whole genom... 44 0.003
UniRef50_A0DCS5 Cluster: Chromosome undetermined scaffold_46, wh... 44 0.003
UniRef50_Q2NFN7 Cluster: Predicted oxidoreductase; n=1; Methanos... 44 0.003
UniRef50_Q3AD20 Cluster: Oxidoreductase, aldo/keto reductase fam... 43 0.005
UniRef50_Q2RJW0 Cluster: Aldo/keto reductase; n=1; Moorella ther... 43 0.005
UniRef50_Q0RGM0 Cluster: Putative aldoketoreductase; n=2; Franki... 43 0.005
UniRef50_Q60BI7 Cluster: Oxidoreductase, aldo/keto reductase fam... 43 0.006
UniRef50_Q1IQ78 Cluster: Aldo/keto reductase; n=1; Acidobacteria... 43 0.006
UniRef50_Q1FGT0 Cluster: Aldo/keto reductase; n=1; Clostridium p... 43 0.006
UniRef50_Q13GB1 Cluster: Aldo/keto reductase; n=1; Burkholderia ... 43 0.006
UniRef50_Q0BAM8 Cluster: Aldo/keto reductase; n=1; Burkholderia ... 43 0.006
UniRef50_Q02C17 Cluster: Aldo/keto reductase precursor; n=1; Sol... 43 0.006
UniRef50_Q1PBI2 Cluster: L-galactose dehydrogenase; n=15; Magnol... 43 0.006
UniRef50_O59826 Cluster: Potassium channel subunit; n=9; cellula... 43 0.006
UniRef50_A3H7G3 Cluster: Aldo/keto reductase; n=2; Caldivirga ma... 43 0.006
UniRef50_Q1U6R9 Cluster: Aldo/keto reductase; n=25; Bacilli|Rep:... 42 0.008
UniRef50_A6W292 Cluster: Aldo/keto reductase; n=9; Bacteria|Rep:... 42 0.008
UniRef50_Q9X0R5 Cluster: Oxidoreductase, aldo/keto reductase fam... 42 0.011
UniRef50_Q89JX0 Cluster: Oxidoreductase; n=26; Bacteria|Rep: Oxi... 42 0.011
UniRef50_Q08VS2 Cluster: Twin-arginine translocation pathway sig... 42 0.011
UniRef50_A1SGJ5 Cluster: Aldo/keto reductase precursor; n=1; Noc... 42 0.011
UniRef50_A0K203 Cluster: Aldo/keto reductase; n=2; Arthrobacter|... 42 0.011
UniRef50_Q6CGE9 Cluster: Similar to sp|P47137 Saccharomyces cere... 42 0.011
UniRef50_Q7UZ40 Cluster: Putative oxidoreductase-possibly Aldo/k... 42 0.014
UniRef50_Q7M4N1 Cluster: Dihydrodiol dehydrogenase DD2; n=2; Hom... 42 0.014
UniRef50_Q8ZYV2 Cluster: Oxidoreductase, conjectural; n=3; Pyrob... 42 0.014
UniRef50_Q39MY8 Cluster: Aldo/keto reductase; n=10; Bacteria|Rep... 41 0.019
UniRef50_A7HL79 Cluster: Aldo/keto reductase; n=1; Fervidobacter... 41 0.019
UniRef50_A6WAE5 Cluster: Aldo/keto reductase; n=1; Kineococcus r... 41 0.019
UniRef50_A3U5K6 Cluster: Oxidoreductase, aldo/keto reductase fam... 41 0.019
UniRef50_Q5ZTU6 Cluster: D-xylose reductase III; n=5; Legionella... 41 0.025
UniRef50_Q2J8X9 Cluster: Aldo/keto reductase; n=3; Frankia|Rep: ... 41 0.025
UniRef50_A5UXT4 Cluster: Aldo/keto reductase; n=2; Roseiflexus|R... 41 0.025
UniRef50_A0YSM3 Cluster: Probable oxidoreductase; n=1; Lyngbya s... 41 0.025
UniRef50_A0Y7Y8 Cluster: Aldo/keto reductase; n=1; marine gamma ... 41 0.025
UniRef50_Q9W2X0 Cluster: CG32688-PA, isoform A; n=4; Sophophora|... 41 0.025
UniRef50_Q75DD3 Cluster: ABR094Wp; n=1; Eremothecium gossypii|Re... 41 0.025
UniRef50_Q6CI80 Cluster: Similar to tr|O59826 Schizosaccharomyce... 41 0.025
UniRef50_Q8YXI8 Cluster: All1225 protein; n=9; Cyanobacteria|Rep... 40 0.032
UniRef50_Q7NJD8 Cluster: Gll1894 protein; n=5; Bacteria|Rep: Gll... 40 0.032
UniRef50_Q191F3 Cluster: Aldo/keto reductase; n=2; Desulfitobact... 40 0.032
UniRef50_A6AKU1 Cluster: Aldo/keto reductase; n=2; Gammaproteoba... 40 0.032
UniRef50_A0JVH3 Cluster: Aldo/keto reductase; n=17; Bacteria|Rep... 40 0.032
UniRef50_Q23TY7 Cluster: Oxidoreductase, aldo/keto reductase fam... 40 0.032
UniRef50_A0C161 Cluster: Chromosome undetermined scaffold_141, w... 40 0.032
UniRef50_UPI0000E87D03 Cluster: Aldo/keto reductase; n=1; Methyl... 40 0.043
UniRef50_UPI00005100E5 Cluster: COG0667: Predicted oxidoreductas... 40 0.043
UniRef50_Q8EUX1 Cluster: Aldo/keto reductase family oxidoreducta... 40 0.043
UniRef50_A6PQ08 Cluster: Aldo/keto reductase precursor; n=1; Vic... 40 0.043
UniRef50_A2SFD3 Cluster: Putative oxidoreductase protein; n=1; M... 40 0.043
UniRef50_A6QVW8 Cluster: Predicted protein; n=1; Ajellomyces cap... 40 0.043
UniRef50_Q97UG6 Cluster: Oxidoreductase; n=5; Archaea|Rep: Oxido... 40 0.043
UniRef50_Q989G0 Cluster: Mlr6441 protein; n=6; Rhizobiales|Rep: ... 40 0.057
UniRef50_Q89RG2 Cluster: Aldo/keto reductase; n=11; Bacteria|Rep... 40 0.057
UniRef50_Q1FHF4 Cluster: Aldo/keto reductase:4Fe-4S ferredoxin, ... 40 0.057
UniRef50_Q0AQX2 Cluster: Aldo/keto reductase; n=1; Maricaulis ma... 40 0.057
UniRef50_Q0DHN0 Cluster: Os05g0456200 protein; n=2; Oryza sativa... 40 0.057
UniRef50_Q55FL2 Cluster: Putative uncharacterized protein; n=1; ... 40 0.057
UniRef50_A1CCJ1 Cluster: Aldo/keto reductase; n=2; Trichocomacea... 40 0.057
UniRef50_Q837G5 Cluster: Oxidoreductase, aldo/keto reductase 2 f... 39 0.075
UniRef50_Q4HND9 Cluster: Oxidoreductase, aldo/keto reductase fam... 39 0.075
UniRef50_Q03UP0 Cluster: Aryl-alcohol dehydrogenase family enzym... 39 0.075
UniRef50_A7BLU0 Cluster: Aldo/keto reductase family; n=1; Beggia... 39 0.075
UniRef50_A4CIJ8 Cluster: Putative uncharacterized protein; n=2; ... 39 0.075
UniRef50_A0LJ47 Cluster: Aldo/keto reductase; n=1; Syntrophobact... 39 0.075
UniRef50_Q2H7K8 Cluster: Putative uncharacterized protein; n=1; ... 39 0.075
UniRef50_Q7VA37 Cluster: Predicted oxidoreductase; n=23; Cyanoba... 39 0.099
UniRef50_Q2AI49 Cluster: Aldo/keto reductase; n=1; Halothermothr... 39 0.099
UniRef50_Q025S3 Cluster: Aldo/keto reductase precursor; n=1; Sol... 39 0.099
UniRef50_A3IX63 Cluster: Putative oxidoreductase; n=1; Cyanothec... 39 0.099
UniRef50_Q295T6 Cluster: GA14985-PA; n=1; Drosophila pseudoobscu... 39 0.099
UniRef50_Q5ASJ7 Cluster: Putative uncharacterized protein; n=1; ... 39 0.099
UniRef50_Q3VQY1 Cluster: Aldo/keto reductase; n=1; Prosthecochlo... 38 0.13
UniRef50_A2WWZ1 Cluster: Putative uncharacterized protein; n=1; ... 38 0.13
UniRef50_Q2UCK9 Cluster: Predicted oxidoreductases; n=16; Pezizo... 38 0.13
UniRef50_A5UJH5 Cluster: Predicted oxidoreductase, aldo/keto red... 38 0.13
UniRef50_Q9VGF3 Cluster: CG18547-PA; n=7; Endopterygota|Rep: CG1... 38 0.17
UniRef50_A5DEF4 Cluster: Putative uncharacterized protein; n=1; ... 38 0.17
UniRef50_UPI0000519C03 Cluster: PREDICTED: similar to CG18547-PA... 38 0.23
UniRef50_Q49V75 Cluster: Putative oxidoreductase; n=1; Staphyloc... 38 0.23
UniRef50_Q2BBT9 Cluster: Probable oxidoreductase protein; n=2; B... 38 0.23
UniRef50_Q1MJ49 Cluster: Putative general stress protein; n=2; R... 38 0.23
UniRef50_A7CYG2 Cluster: Oxidoreductase domain protein; n=2; Opi... 38 0.23
UniRef50_A1RAH7 Cluster: Oxidoreductase, aldo/keto reductase fam... 38 0.23
UniRef50_A5BYJ4 Cluster: Putative uncharacterized protein; n=1; ... 38 0.23
UniRef50_Q8YAN3 Cluster: Lmo0084 protein; n=11; Listeria monocyt... 37 0.30
UniRef50_Q39UW6 Cluster: Oxidoreductase, aldo/keto reductase fam... 37 0.30
UniRef50_Q28R03 Cluster: Aldo/keto reductase; n=4; Alphaproteoba... 37 0.30
UniRef50_Q9YBV5 Cluster: Putative uncharacterized protein; n=1; ... 37 0.30
UniRef50_Q97UJ7 Cluster: Oxidoreductase; n=4; Archaea|Rep: Oxido... 37 0.30
UniRef50_A5UL55 Cluster: Predicted oxidoreductase, aldo/keto red... 37 0.30
UniRef50_P54569 Cluster: Uncharacterized oxidoreductase yqkF; n=... 37 0.30
UniRef50_Q8A955 Cluster: Aldo/keto reductase; n=8; Bacteroidales... 37 0.40
UniRef50_Q4IVF8 Cluster: Aldo/keto reductase; n=22; Gammaproteob... 37 0.40
UniRef50_Q1IH94 Cluster: Aldo/keto reductase; n=2; Bacteria|Rep:... 37 0.40
UniRef50_Q0B0F0 Cluster: Oxidoreductase; n=1; Syntrophomonas wol... 37 0.40
UniRef50_Q04TM6 Cluster: Aryl-alcohol dehydrogenase-related oxid... 37 0.40
UniRef50_A7B5J6 Cluster: Putative uncharacterized protein; n=1; ... 37 0.40
UniRef50_Q55ML8 Cluster: Putative uncharacterized protein; n=2; ... 37 0.40
UniRef50_Q2H7Q3 Cluster: Putative uncharacterized protein; n=1; ... 37 0.40
UniRef50_Q97ZZ1 Cluster: Oxidoreductase; n=4; Sulfolobaceae|Rep:... 37 0.40
UniRef50_P49261 Cluster: Rho beta-crystallin; n=1; Lepidodactylu... 37 0.40
UniRef50_Q5ZRR0 Cluster: Aldo/keto reductase; n=3; Legionella pn... 36 0.53
UniRef50_Q1VSU3 Cluster: Aryl-alcohol dehydrogenase; n=1; Psychr... 36 0.53
UniRef50_Q01RI8 Cluster: Aldo/keto reductase precursor; n=1; Sol... 36 0.53
UniRef50_A1SJZ0 Cluster: Aldo/keto reductase; n=11; Actinomyceta... 36 0.53
UniRef50_A0ZZJ3 Cluster: Oxidoreductase; n=2; Bifidobacterium ad... 36 0.53
UniRef50_A0V7Q3 Cluster: Aldo/keto reductase precursor; n=5; Pro... 36 0.53
UniRef50_A7TRU8 Cluster: Putative uncharacterized protein; n=1; ... 36 0.53
UniRef50_O43488 Cluster: Aflatoxin B1 aldehyde reductase member ... 36 0.53
UniRef50_UPI00015B403B Cluster: PREDICTED: similar to CG18547-PA... 36 0.70
UniRef50_Q87SA8 Cluster: Oxidoreductase Tas, aldo/keto reductase... 36 0.70
UniRef50_A6RHV7 Cluster: Putative uncharacterized protein; n=2; ... 36 0.70
UniRef50_UPI0000DAE567 Cluster: hypothetical protein Rgryl_01000... 36 0.92
UniRef50_Q6XUT6 Cluster: Oxido-reductase/dehydratase; n=3; Bacte... 36 0.92
UniRef50_Q08NK7 Cluster: Aldo/keto reductase; n=1; Stigmatella a... 36 0.92
UniRef50_A5ZM37 Cluster: Putative uncharacterized protein; n=1; ... 36 0.92
UniRef50_A5FAZ9 Cluster: Aldo/keto reductase; n=1; Flavobacteriu... 36 0.92
UniRef50_A1SEE9 Cluster: Aldo/keto reductase; n=1; Nocardioides ... 36 0.92
UniRef50_A1B5W4 Cluster: Aldo/keto reductase; n=1; Paracoccus de... 36 0.92
UniRef50_A0K1H5 Cluster: Aldo/keto reductase; n=6; Actinomycetal... 36 0.92
UniRef50_A1CGI8 Cluster: Aldo-keto reductase (AKR13), puatative;... 36 0.92
UniRef50_Q9F3N3 Cluster: Putative oxidoreductase; n=3; Actinomyc... 35 1.2
UniRef50_Q67NQ1 Cluster: Oxidoreductase; n=1; Symbiobacterium th... 35 1.2
UniRef50_Q099T4 Cluster: Oxidoreductase; n=2; Proteobacteria|Rep... 35 1.2
UniRef50_A1WW73 Cluster: Aldo/keto reductases related to diketog... 35 1.2
UniRef50_Q5K978 Cluster: Aryl-alcohol dehydrogenase, putative; n... 35 1.2
>UniRef50_Q8WRT0 Cluster: 3-dehydrecdysone 3b-reductase; n=1;
Trichoplusia ni|Rep: 3-dehydrecdysone 3b-reductase -
Trichoplusia ni (Cabbage looper)
Length = 308
Score = 125 bits (301), Expect = 9e-28
Identities = 77/171 (45%), Positives = 105/171 (61%), Gaps = 7/171 (4%)
Frame = +1
Query: 37 VFVITTLIVHLSEATTGG-GKASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKP 213
++++ + L A +G GKA LNDGN+IP+L LGTF GF + + +
Sbjct: 3 LYLLPVALWALVNAISGEPGKAPLKQLNDGNAIPSLALGTF-GFGDIPKVR-------QA 54
Query: 214 VKWALEAGYRLIDTAALYLNEDQIGA----AVRASGIPREDIFIVTKLPMD--NQRDVVK 375
V WA++AGYR IDTAALY NE+++G A++ + RE++F+ TKL D + VV
Sbjct: 55 VLWAIQAGYRHIDTAALYGNEEEVGKGIADAIQQGLVKREELFVTTKLWNDKHGRHQVVP 114
Query: 376 QLEKSLARLNMSYVDLYLIHNPVAFNPGFKGFDIVDYLDTWKGMEEAKNLG 528
L +SL +L +SYVDLYLIH+P A N DI D L+TW GMEEAK LG
Sbjct: 115 ALRESLTKLGLSYVDLYLIHSPEATNENGDPVDI-DVLNTWNGMEEAKKLG 164
>UniRef50_A5E082 Cluster: GCY protein; n=4; Saccharomycetales|Rep:
GCY protein - Lodderomyces elongisporus (Yeast)
(Saccharomyces elongisporus)
Length = 295
Score = 113 bits (272), Expect = 3e-24
Identities = 59/136 (43%), Positives = 88/136 (64%), Gaps = 1/136 (0%)
Frame = +1
Query: 109 SLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIG 288
+LN+G IPA+GLGT+L +E + K AL+ GY+ IDTAA Y NEDQ+G
Sbjct: 13 TLNNGLKIPAIGLGTWLADEEDA--------AYKATLTALKNGYKHIDTAAAYGNEDQVG 64
Query: 289 AAVRASGIPREDIFIVTKLPMDNQRDVVKQLEKSLARLNMSYVDLYLIHNPVAFNPGF-K 465
A+ SG+ R++IF+ TKL D +D L++SL +L + YVDLYLIH P++ +P K
Sbjct: 65 RAIADSGVSRDEIFVTTKLWNDQHKDPEGALDESLKKLGLEYVDLYLIHWPLSVDPKTEK 124
Query: 466 GFDIVDYLDTWKGMEE 513
+D D++DTW+ +++
Sbjct: 125 PYDDYDFVDTWRNLQK 140
>UniRef50_UPI00015B56A2 Cluster: PREDICTED: similar to GA10458-PA;
n=2; Nasonia vitripennis|Rep: PREDICTED: similar to
GA10458-PA - Nasonia vitripennis
Length = 569
Score = 113 bits (271), Expect = 4e-24
Identities = 67/157 (42%), Positives = 89/157 (56%), Gaps = 16/157 (10%)
Frame = +1
Query: 106 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 285
++ NDG +P +GLGTFL KPG+ + VK+A+E GYR +DTA Y NE +I
Sbjct: 6 VTFNDGYKMPMIGLGTFLS---------KPGEVAEAVKYAIEVGYRHVDTAFFYENEKEI 56
Query: 286 GAAVRA----SGIPREDIFIVTKLPMDNQR--DVVKQLEKSLARLNMSYVDLYLIHNPVA 447
G+A+R I REDIF+ TKL ++ + +VV +KSL L Y+DL+L+H P A
Sbjct: 57 GSAIREKINDGTIKREDIFVTTKLWCNSHKEDEVVPACKKSLENLGFDYIDLFLVHWPFA 116
Query: 448 FNPGFK----------GFDIVDYLDTWKGMEEAKNLG 528
F G F DYL+TWKGMEE K G
Sbjct: 117 FKSGDALTPRDAAGKIEFSDTDYLETWKGMEECKRQG 153
Score = 76.6 bits (180), Expect = 4e-13
Identities = 48/110 (43%), Positives = 60/110 (54%), Gaps = 13/110 (11%)
Frame = +1
Query: 238 YRLIDTAALYLNEDQIGAAVRAS----GIPREDIFIVTKLPM--DNQRDVVKQLEKSLAR 399
YR IDTA LY NE IG A+R + RED+F+ TKL + +VV ++SL
Sbjct: 301 YRHIDTAYLYDNEKYIGNAIREKIKDGTVKREDLFVTTKLSYYAHKESEVVPACKQSLND 360
Query: 400 LNMSYVDLYLIHNPVA----FNPGFKG---FDIVDYLDTWKGMEEAKNLG 528
L + Y+DLYLIH P+ N G DYL+TWKGMEE K G
Sbjct: 361 LGLDYIDLYLIHWPIRRYFRHNKNASGKLLLSDTDYLETWKGMEECKRQG 410
>UniRef50_A1UEC5 Cluster: 2,5-didehydrogluconate reductase; n=20;
Corynebacterineae|Rep: 2,5-didehydrogluconate reductase
- Mycobacterium sp. (strain KMS)
Length = 283
Score = 112 bits (269), Expect = 7e-24
Identities = 68/143 (47%), Positives = 86/143 (60%), Gaps = 2/143 (1%)
Frame = +1
Query: 106 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 285
+SLNDG+SIP LGLG E+ ++E+ V ALEAGYRLIDTAA+Y NE +
Sbjct: 14 VSLNDGHSIPVLGLGV---------GELSEAEAERSVAAALEAGYRLIDTAAVYGNEAAV 64
Query: 286 GAAVRASGIPREDIFIVTKLPMDNQRDVVKQ--LEKSLARLNMSYVDLYLIHNPVAFNPG 459
G AV ASGIPRE+I++ TKL + +Q Q SL RL + YVDLYLIH P
Sbjct: 65 GRAVNASGIPREEIYVTTKLAVADQGFGTSQDAARASLERLGLDYVDLYLIHWPAG---- 120
Query: 460 FKGFDIVDYLDTWKGMEEAKNLG 528
D Y+D+W G+ +AK G
Sbjct: 121 ----DHGKYIDSWGGLMKAKQDG 139
>UniRef50_UPI00015B56A3 Cluster: PREDICTED: similar to aldo-keto
reductase; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to aldo-keto reductase - Nasonia vitripennis
Length = 321
Score = 107 bits (258), Expect = 1e-22
Identities = 63/161 (39%), Positives = 95/161 (59%), Gaps = 16/161 (9%)
Frame = +1
Query: 94 KASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN 273
K +I+L+DGN +P LGLGT+ G ++ P + E VK A++AGYR D A+ Y N
Sbjct: 4 KVDEITLSDGNKVPVLGLGTWQGGND-------PDEVENAVKLAIDAGYRHFDCASFYGN 56
Query: 274 EDQIGAAVR----ASGIPREDIFIVTKLPMDNQRD--VVKQLEKSLARLNMSYVDLYLIH 435
E +IG A++ + RED+F+VTK+ D ++ VV ++SL +L + Y+DLYL+H
Sbjct: 57 EAEIGKAIQEKIDQGVVKREDLFVVTKVWNDERKQELVVAACKRSLKKLGLGYIDLYLVH 116
Query: 436 NPVAFN--------PGFKG--FDIVDYLDTWKGMEEAKNLG 528
P ++ P + D VDY++TW+GMEE LG
Sbjct: 117 WPFSYPILYQYIVLPTYNAVTLDEVDYIETWRGMEECIKLG 157
>UniRef50_P14065 Cluster: Protein GCY; n=13; Saccharomycetales|Rep:
Protein GCY - Saccharomyces cerevisiae (Baker's yeast)
Length = 312
Score = 107 bits (257), Expect = 2e-22
Identities = 58/126 (46%), Positives = 79/126 (62%), Gaps = 1/126 (0%)
Frame = +1
Query: 106 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 285
+SLN G IP +GLGT+ + K D+ K V AL+ GYR IDTAA+Y NEDQ+
Sbjct: 12 LSLNTGAQIPQIGLGTW---------QSKENDAYKAVLTALKDGYRHIDTAAIYRNEDQV 62
Query: 286 GAAVRASGIPREDIFIVTKLPMDNQRDVVKQLEKSLARLNMSYVDLYLIHNPVAFNPGF- 462
G A++ SG+PRE+IF+ TKL + L++SL RL + YVDLYL+H P +P +
Sbjct: 63 GQAIKDSGVPREEIFVTTKLWCTQHHEPEVALDQSLKRLGLDYVDLYLMHWPARLDPAYI 122
Query: 463 KGFDIV 480
K DI+
Sbjct: 123 KNEDIL 128
>UniRef50_Q1VRG6 Cluster: YvgN; n=1; Psychroflexus torquis ATCC
700755|Rep: YvgN - Psychroflexus torquis ATCC 700755
Length = 280
Score = 107 bits (256), Expect = 2e-22
Identities = 61/143 (42%), Positives = 90/143 (62%), Gaps = 3/143 (2%)
Frame = +1
Query: 109 SLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIG 288
+LNDGN IP +G GT+ +E+G K ++ K AL GYRLIDT A+Y NE+ +G
Sbjct: 4 NLNDGNRIPIVGFGTYKANEEEGIKSIQ--------KSALTLGYRLIDTVAIYQNEEAVG 55
Query: 289 AAVRASGIPREDIFIVTKLPMDN--QRDVVKQLEKSLARLNMSYVDLYLIHNPV-AFNPG 459
A++A G+ RE+IF+ TKL +N + L++SL +L+++Y+DLYLIH P A N
Sbjct: 56 KAIKARGVLREEIFVTTKLWRENLGYKQTRIALDESLRKLDLNYIDLYLIHWPANAIN-- 113
Query: 460 FKGFDIVDYLDTWKGMEEAKNLG 528
+K + + DTW+ MEE + G
Sbjct: 114 YKDWQKTN-ADTWRAMEELQAEG 135
>UniRef50_A0JRJ6 Cluster: Aldo/keto reductase; n=2;
Micrococcineae|Rep: Aldo/keto reductase - Arthrobacter
sp. (strain FB24)
Length = 281
Score = 103 bits (248), Expect = 2e-21
Identities = 62/137 (45%), Positives = 82/137 (59%)
Frame = +1
Query: 103 KISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQ 282
+++LN+G IP LG G F +V P ++++ V+ ALEAGYR IDTAA Y NE
Sbjct: 11 QLTLNNGVKIPQLGFGVF---------QVPPEETQRIVEDALEAGYRHIDTAAAYRNEAG 61
Query: 283 IGAAVRASGIPREDIFIVTKLPMDNQRDVVKQLEKSLARLNMSYVDLYLIHNPVAFNPGF 462
+GAA+ ASGIPREDIFI TKL Q + + + S L + +VDLYLIH PV + G
Sbjct: 62 VGAAISASGIPREDIFITTKLRNGEQGNAHEAFQNSRKALGVEFVDLYLIHWPVP-SQGL 120
Query: 463 KGFDIVDYLDTWKGMEE 513
Y + WK ME+
Sbjct: 121 -------YTEAWKAMEK 130
>UniRef50_UPI000023D0F1 Cluster: hypothetical protein FG03517.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG03517.1 - Gibberella zeae PH-1
Length = 364
Score = 103 bits (247), Expect = 3e-21
Identities = 65/159 (40%), Positives = 97/159 (61%), Gaps = 5/159 (3%)
Frame = +1
Query: 67 LSEATT-GGGKASKISLNDG-NSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGY 240
LS AT+ G + + + N+ IPA GLGT+L G+ V P V++AL+ GY
Sbjct: 37 LSIATSFGPAEMPEFNKNETVRDIPAFGLGTWLA----GKGVVVPA-----VEYALKGGY 87
Query: 241 RLIDTAALYLNEDQIGAAVRASGIPREDIFIVTKL-PMDNQRDVV-KQLEKSLARLNMSY 414
R IDTA ++ NED++G ++ASG+ R++I++ KL D++ ++V K +E S+A L + Y
Sbjct: 88 RHIDTALIWRNEDEVGKGIKASGVSRDEIWVTGKLWNTDHRPELVRKAIETSIANLGVEY 147
Query: 415 VDLYLIHNPVAFNPGFKGFD-IVDYLDTWKGMEEAKNLG 528
+DLYLIH PVA+ P + D +DTWK MEE G
Sbjct: 148 LDLYLIHYPVAWVPETRDVDNNTSLIDTWKAMEELVRAG 186
>UniRef50_Q0CK00 Cluster: Predicted protein; n=1; Aspergillus
terreus NIH2624|Rep: Predicted protein - Aspergillus
terreus (strain NIH 2624)
Length = 292
Score = 102 bits (245), Expect = 5e-21
Identities = 56/141 (39%), Positives = 79/141 (56%)
Frame = +1
Query: 106 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 285
+SL DGN +P LG GT + + + + + +K ALE G+ ID A Y E ++
Sbjct: 6 LSLKDGNLVPILGFGTGTAWYKDDPNDPTNPELIEVLKAALEKGFHHIDAADSYGTEREV 65
Query: 286 GAAVRASGIPREDIFIVTKLPMDNQRDVVKQLEKSLARLNMSYVDLYLIHNPVAFNPGFK 465
G A+R SGIPRE +FI TK+ ++ +DV L+ SL RL + YVDLYL+HNP
Sbjct: 66 GIAIRESGIPREQLFITTKV-LEGWKDVPGALDASLERLQLDYVDLYLLHNPYVIP---- 120
Query: 466 GFDIVDYLDTWKGMEEAKNLG 528
++ D WKG+E K G
Sbjct: 121 --NLTDIQSAWKGLEAVKATG 139
>UniRef50_Q8K023 Cluster: Aldo-keto reductase family 1 member C18;
n=72; Tetrapoda|Rep: Aldo-keto reductase family 1 member
C18 - Mus musculus (Mouse)
Length = 323
Score = 102 bits (245), Expect = 5e-21
Identities = 67/161 (41%), Positives = 93/161 (57%), Gaps = 16/161 (9%)
Frame = +1
Query: 94 KASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN 273
K KI LNDG+SIP LG GT+ + +K S + K A++ G+ ID + LY N
Sbjct: 4 KIQKIELNDGHSIPVLGFGTYATEEHLKKK------SMESTKIAIDVGFCHIDCSHLYQN 57
Query: 274 EDQIGAAVRAS----GIPREDIFIVTKLPMDNQR-DVVK-QLEKSLARLNMSYVDLYLIH 435
E++IG A+ + + REDIF +KL + R ++V+ LE SL +LN+ YVDLYLIH
Sbjct: 58 EEEIGQAILSKIEDGTVKREDIFYTSKLWSTSHRPELVRPSLENSLRKLNLDYVDLYLIH 117
Query: 436 NPVAFNPGFK-------G---FDIVDYLDTWKGMEEAKNLG 528
PV+ PG + G FD VD DTW+ ME+ K+ G
Sbjct: 118 FPVSLKPGNELLPKDEHGNLIFDTVDLCDTWEAMEKCKDAG 158
>UniRef50_P06632 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=8; Actinomycetales|Rep: 2,5-diketo-D-gluconic acid
reductase A - Corynebacterium sp. (strain ATCC 31090)
Length = 278
Score = 102 bits (244), Expect = 7e-21
Identities = 57/114 (50%), Positives = 74/114 (64%), Gaps = 2/114 (1%)
Frame = +1
Query: 106 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 285
I LNDGNSIP LG G F +V P D+++ V+ ALE GYR IDTAA+Y NE+ +
Sbjct: 6 IVLNDGNSIPQLGYGVF---------KVPPADTQRAVEEALEVGYRHIDTAAIYGNEEGV 56
Query: 286 GAAVRASGIPREDIFIVTKLPMDNQ--RDVVKQLEKSLARLNMSYVDLYLIHNP 441
GAA+ ASGI R+D+FI TKL D + + +SLA+L + VDLYL+H P
Sbjct: 57 GAAIAASGIARDDLFITTKLWNDRHDGDEPAAAIAESLAKLALDQVDLYLVHWP 110
>UniRef50_Q88TV9 Cluster: Oxidoreductase; n=4; Lactobacillus|Rep:
Oxidoreductase - Lactobacillus plantarum
Length = 288
Score = 100 bits (240), Expect = 2e-20
Identities = 55/124 (44%), Positives = 77/124 (62%), Gaps = 2/124 (1%)
Frame = +1
Query: 94 KASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN 273
K I+LNDG +IPA+G GTF D+ G + + VK AL GYR IDTA Y N
Sbjct: 3 KTPTITLNDGRAIPAIGFGTFQIPDD--------GSTYQAVKEALVIGYRHIDTAVAYFN 54
Query: 274 EDQIGAAVRASGIPREDIFIVTKLPM-DNQRDVV-KQLEKSLARLNMSYVDLYLIHNPVA 447
ED++G A++ SGIPR+ I++ +KL + D D + +++SL +L + Y+DLYLIH P
Sbjct: 55 EDEVGQAIKDSGIPRDQIWVTSKLWLQDYGFDAASRAIDRSLTKLRLDYIDLYLIHQPYG 114
Query: 448 FNPG 459
PG
Sbjct: 115 DVPG 118
>UniRef50_A3U9Y0 Cluster: Aldehyde reductase; n=5;
Bacteroidetes|Rep: Aldehyde reductase - Croceibacter
atlanticus HTCC2559
Length = 316
Score = 100 bits (240), Expect = 2e-20
Identities = 61/143 (42%), Positives = 84/143 (58%), Gaps = 6/143 (4%)
Frame = +1
Query: 106 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 285
+ DG+SIP++GLGT+ + P D +K VK ALE GY+ ID AA Y NED +
Sbjct: 4 LKFRDGDSIPSIGLGTW---------KSDPEDVKKAVKIALENGYKHIDCAAAYDNEDAV 54
Query: 286 GAAVRAS----GIPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIHNPVA 447
G A + S + REDIF+ +KL + DV+ L+K+L LN+ Y+DLYL+H PVA
Sbjct: 55 GEAFKESFESGNVKREDIFVTSKLWNNAHKKEDVIPALKKTLKDLNLDYLDLYLMHWPVA 114
Query: 448 FNPGFKGFDIVDYLDTWKGMEEA 516
F P GF D + + +EEA
Sbjct: 115 FKPSVNGFPEKD--EDYLSLEEA 135
>UniRef50_Q9Y020 Cluster: 3-dehydroecdysone 3beta-reductase
precursor; n=1; Spodoptera littoralis|Rep:
3-dehydroecdysone 3beta-reductase precursor - Spodoptera
littoralis (Egyptian cotton leafworm)
Length = 345
Score = 100 bits (240), Expect = 2e-20
Identities = 56/145 (38%), Positives = 82/145 (56%), Gaps = 6/145 (4%)
Frame = +1
Query: 112 LNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGA 291
LND +PA+ LGT+LGFD+ G K V A++ GYR DTAA+Y E ++G
Sbjct: 28 LND-REMPAIALGTYLGFDKGGAVTSKDKQLRNVVMQAIDLGYRHFDTAAIYNTEAEVGE 86
Query: 292 AVR----ASGIPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIHNPVAFN 453
A+R I RED+F+ TKL + V ++++L + + YVDL+L+H P+A N
Sbjct: 87 AIRMKIDEGVIKREDVFLTTKLWNTHHKREQVAVAMKETLNKTGLDYVDLFLMHWPIALN 146
Query: 454 PGFKGFDIVDYLDTWKGMEEAKNLG 528
+ + DYL+TW+ EE LG
Sbjct: 147 EDYSHSN-TDYLETWRATEEMVKLG 170
>UniRef50_Q8VC28 Cluster: Aldo-keto reductase family 1 member C13;
n=11; Theria|Rep: Aldo-keto reductase family 1 member
C13 - Mus musculus (Mouse)
Length = 323
Score = 100 bits (240), Expect = 2e-20
Identities = 66/157 (42%), Positives = 88/157 (56%), Gaps = 16/157 (10%)
Frame = +1
Query: 106 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 285
+ LNDG+ IPALG GT+ KEV S + AL+ GYR +DTA Y E++I
Sbjct: 8 VKLNDGHLIPALGFGTYK------PKEVPKSKSLEAACLALDVGYRHVDTAYAYQVEEEI 61
Query: 286 GAA----VRASGIPREDIFIVTKLPMDNQR-DVVK-QLEKSLARLNMSYVDLYLIHNPVA 447
G A ++A + RED+FI TKL R ++VK LEKSL +L + YVDLY++H PV
Sbjct: 62 GQAIQSKIKAGVVKREDLFITTKLWCTCFRPELVKPALEKSLKKLQLDYVDLYIMHYPVP 121
Query: 448 FNPGFKGF----------DIVDYLDTWKGMEEAKNLG 528
G F D VD+ DTW+ +EE K+ G
Sbjct: 122 MKSGDNDFPVNEQGKSLLDTVDFCDTWERLEECKDAG 158
>UniRef50_A2QBD7 Cluster: Catalytic activity: an alcohol + NADP(+)
<=> an aldehyde + NADPH; n=4; Trichocomaceae|Rep:
Catalytic activity: an alcohol + NADP(+) <=> an aldehyde
+ NADPH - Aspergillus niger
Length = 323
Score = 99 bits (238), Expect = 4e-20
Identities = 60/150 (40%), Positives = 85/150 (56%), Gaps = 12/150 (8%)
Frame = +1
Query: 100 SKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNED 279
S ++N G IPA+G GT+ + KP + E V+ AL GYR ID AA+Y NE
Sbjct: 5 SHFTINTGAKIPAVGFGTW---------QAKPLEVENAVEVALREGYRHIDCAAIYRNET 55
Query: 280 QIGAAVRASGIPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIHNPVAFN 453
++G +R SG+PRE+IFI KL DV L+K+L L ++Y+DLYL+H P AF
Sbjct: 56 EVGNGIRKSGVPREEIFITGKLWNTKHAPEDVEPALDKTLQDLGVAYLDLYLMHWPCAFK 115
Query: 454 PGFKGFDI----------VDYLDTWKGMEE 513
G K F + +DY+ T++ ME+
Sbjct: 116 GGDKWFPLNDDGVFDLANIDYITTYRAMEK 145
>UniRef50_P22045 Cluster: Probable reductase; n=101; cellular
organisms|Rep: Probable reductase - Leishmania major
Length = 284
Score = 99 bits (238), Expect = 4e-20
Identities = 61/149 (40%), Positives = 86/149 (57%), Gaps = 7/149 (4%)
Frame = +1
Query: 88 GGKASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALY 267
G + ++L++G +P GLG + + EV +E V WAL AGYR IDTAA+Y
Sbjct: 3 GVDKAMVTLSNGVKMPQFGLGVW----QSPAGEV----TENAVNWALCAGYRHIDTAAIY 54
Query: 268 LNEDQIGAAVRASGIPREDIFIVTKLPMDNQ--RDVVKQLEKSLARLNMSYVDLYLIHNP 441
NE+ +GA +RASG+PRED+FI TKL Q + E+S +L + Y+DLYLIH P
Sbjct: 55 KNEESVGAGLRASGVPREDVFITTKLWNTEQGYESTLAAFEESRQKLGVDYIDLYLIHWP 114
Query: 442 VAFNPGFKGFDIVD-----YLDTWKGMEE 513
+G DI+ YLD+W+ E+
Sbjct: 115 -------RGKDILSKEGKKYLDSWRAFEQ 136
>UniRef50_Q88SL1 Cluster: Oxidoreductase; n=51; Lactobacillales|Rep:
Oxidoreductase - Lactobacillus plantarum
Length = 286
Score = 99.5 bits (237), Expect = 5e-20
Identities = 65/140 (46%), Positives = 85/140 (60%), Gaps = 4/140 (2%)
Frame = +1
Query: 109 SLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIG 288
+LN+G IP +G GT+ D GQ DS V AL+AGYR IDTAA Y NE+ +G
Sbjct: 12 TLNNGTKIPIVGFGTWQTPD--GQVAY---DS---VLAALKAGYRHIDTAAAYGNEESVG 63
Query: 289 AAVRASGIPREDIFIVTKL-PMDNQRDVVKQ-LEKSLARLNMSYVDLYLIH--NPVAFNP 456
A+ SG+ RED+F+ TKL D+ D K+ L+ SLA+L + YVDLYLIH NP A
Sbjct: 64 KAIADSGVAREDLFVTTKLWNADHGYDAAKKALDTSLAKLGLDYVDLYLIHWPNPAAMRD 123
Query: 457 GFKGFDIVDYLDTWKGMEEA 516
++ + DTW+ MEEA
Sbjct: 124 NWEQLN----ADTWRAMEEA 139
>UniRef50_Q68ST9 Cluster: Reductase AKOR2; n=2; Pleurotus
djamor|Rep: Reductase AKOR2 - Pleurotus djamor
Length = 306
Score = 97.5 bits (232), Expect = 2e-19
Identities = 50/112 (44%), Positives = 68/112 (60%)
Frame = +1
Query: 106 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 285
I LN G +PAL LG + G E+ + + K AL++GYR IDTA +Y E +
Sbjct: 7 IVLNTGARMPALALGGWAGLTEEERTQAKEW-----FLTALKSGYRHIDTAQIYYTEKSV 61
Query: 286 GAAVRASGIPREDIFIVTKLPMDNQRDVVKQLEKSLARLNMSYVDLYLIHNP 441
G A+R SGIPRE++FI TKLP ++ V + +KSL L Y+DLYL+H P
Sbjct: 62 GNAIRESGIPREELFITTKLPWNHHSRVAESFQKSLENLGTEYIDLYLVHFP 113
>UniRef50_Q9HGY0 Cluster: Glycerol dehydrogenase; n=8;
Saccharomycetaceae|Rep: Glycerol dehydrogenase -
Zygosaccharomyces rouxii (Candida mogii)
Length = 310
Score = 97.1 bits (231), Expect = 3e-19
Identities = 52/115 (45%), Positives = 74/115 (64%)
Frame = +1
Query: 100 SKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNED 279
S + LN G +IP +GLGT+ + +G K V AL+AGYR ID AA+Y NE
Sbjct: 9 STLKLNTGQTIPQVGLGTWRSKENEGYKAVIE---------ALKAGYRHIDGAAVYGNEG 59
Query: 280 QIGAAVRASGIPREDIFIVTKLPMDNQRDVVKQLEKSLARLNMSYVDLYLIHNPV 444
++G A++ SG+PR +IF+ TKL +QR+ + L++SL RL + YV LYL+H PV
Sbjct: 60 EVGKAIQDSGVPRNEIFLTTKLWCTHQRNPQEALDQSLQRLGLDYVGLYLVHWPV 114
>UniRef50_Q16K66 Cluster: Aldo-keto reductase; n=2; Aedes
aegypti|Rep: Aldo-keto reductase - Aedes aegypti
(Yellowfever mosquito)
Length = 303
Score = 96.7 bits (230), Expect = 4e-19
Identities = 64/154 (41%), Positives = 88/154 (57%), Gaps = 13/154 (8%)
Frame = +1
Query: 106 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 285
++LN+G+SIP +GLGT+ ++ D +K A+E GYRLIDTA +Y NE +
Sbjct: 2 LALNNGHSIPPIGLGTY---------KITGSDGVAAIKSAVEFGYRLIDTAFVYNNEQVV 52
Query: 286 GAAVR-----ASGIPREDIFIVTKL-PMDNQRDVV-KQLEKSLARLNMSYVDLYLIHNPV 444
G A+R + I RED+FIV+KL P ++ + V K SL RL + YVDLYL+H PV
Sbjct: 53 GQALREIFSQGNDINREDVFIVSKLGPTFHRPEAVEKGCRLSLERLGLDYVDLYLMHTPV 112
Query: 445 AFNPGFKG------FDIVDYLDTWKGMEEAKNLG 528
A G D V L+TWK +EE + G
Sbjct: 113 AARDSGDGNDRSEIDDEVTPLETWKALEECQRKG 146
>UniRef50_Q1U9L6 Cluster: 2,5-didehydrogluconate reductase; n=3;
Lactobacillus|Rep: 2,5-didehydrogluconate reductase -
Lactobacillus reuteri 100-23
Length = 288
Score = 96.3 bits (229), Expect = 5e-19
Identities = 61/147 (41%), Positives = 83/147 (56%), Gaps = 4/147 (2%)
Frame = +1
Query: 100 SKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGD-SEKPVKWALEAGYRLIDTAALYLNE 276
S +LN+G IP +G GTF P D +E+ VK A+E GYR IDTAA+Y NE
Sbjct: 9 STFNLNNGVKIPCVGYGTFR----------TPADVAEQAVKEAIETGYRHIDTAAVYGNE 58
Query: 277 DQIGAAVRASGIPREDIFIVTKLPMDNQ--RDVVKQLEKSLARLNMSYVDLYLIHNPVAF 450
+ +G ++ SGI RED+F+ +KL N+ K +++L RL M Y+DLYLIH P
Sbjct: 59 EAVGKGIKDSGIKREDLFVTSKLWNTNRGYEQTKKAFQETLDRLQMDYLDLYLIHWPA-- 116
Query: 451 NPGFKGFDIVDY-LDTWKGMEEAKNLG 528
N G D +TW+ ME+ N G
Sbjct: 117 NEKQFGDDAAKINAETWRAMEDLYNEG 143
>UniRef50_A7CUW0 Cluster: 2,5-didehydrogluconate reductase; n=6;
Bacteria|Rep: 2,5-didehydrogluconate reductase -
Opitutaceae bacterium TAV2
Length = 334
Score = 96.3 bits (229), Expect = 5e-19
Identities = 55/140 (39%), Positives = 81/140 (57%), Gaps = 2/140 (1%)
Frame = +1
Query: 106 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 285
+ L+DG SIP LGLG + ++ + P++ A AGYR IDTA +Y NE+ +
Sbjct: 62 LPLSDGTSIPQLGLGVW---------QMPDDGAGVPIQAAFNAGYRAIDTAPIYGNEEGV 112
Query: 286 GAAVRASGIPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIHNPVAFNPG 459
G A+RASG+PR++++I TK+ ++ + +SL RL + YVDLYLIH PV
Sbjct: 113 GRAIRASGLPRKELYITTKVWNSAQGYDSTLRAVRESLGRLQLEYVDLYLIHWPVP---- 168
Query: 460 FKGFDIVDYLDTWKGMEEAK 519
I Y+DTWK + + K
Sbjct: 169 ----KIDRYVDTWKALAKIK 184
>UniRef50_Q4P4P1 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 322
Score = 96.3 bits (229), Expect = 5e-19
Identities = 57/160 (35%), Positives = 86/160 (53%), Gaps = 4/160 (2%)
Frame = +1
Query: 61 VHLSEATTGGGKASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGY 240
V S +G +I LN+G IP + LG + K G +E KWA +AGY
Sbjct: 4 VTASGIISGNISTQRIKLNNGQEIPQVALGVY--------KAPNDGSTENACKWAFDAGY 55
Query: 241 RLIDTAALYLNEDQIGAAV----RASGIPREDIFIVTKLPMDNQRDVVKQLEKSLARLNM 408
R ID+AA Y+NE+ +G A+ + + +PR +IFI +KL + +E SL +LN+
Sbjct: 56 RHIDSAARYMNEESVGRALAEWTKENNVPRSEIFITSKLWDADHDKAAAAIEDSLKKLNV 115
Query: 409 SYVDLYLIHNPVAFNPGFKGFDIVDYLDTWKGMEEAKNLG 528
Y+D+YL+H +PG G + L+ WK +EEA + G
Sbjct: 116 DYMDMYLMH-----SPGTMGAE--KRLEAWKALEEAVDAG 148
>UniRef50_Q83N50 Cluster: 2,5-diketo-D-gluconic acid reductase; n=2;
Tropheryma whipplei|Rep: 2,5-diketo-D-gluconic acid
reductase - Tropheryma whipplei (strain Twist)
(Whipple's bacillus)
Length = 283
Score = 95.9 bits (228), Expect = 6e-19
Identities = 58/143 (40%), Positives = 82/143 (57%)
Frame = +1
Query: 106 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 285
+ L DG SIP GLGT+ E+ P ++ V+ A+E GYR IDTA+LY NE ++
Sbjct: 12 VLLGDGVSIPQFGLGTY---------ELPPNEASSVVQSAIELGYRHIDTASLYANEREV 62
Query: 286 GAAVRASGIPREDIFIVTKLPMDNQRDVVKQLEKSLARLNMSYVDLYLIHNPVAFNPGFK 465
G A+ +SGI RE+ F+ TKL +Q + E+SL L++ YVDLYLIH P P
Sbjct: 63 GRAIASSGIKREEFFVTTKLWNSDQPKPREAFERSLDLLSLDYVDLYLIHWPCP--PSEL 120
Query: 466 GFDIVDYLDTWKGMEEAKNLGPS 534
++ + L K AK++G S
Sbjct: 121 YINVWEVLLELKESGRAKSVGVS 143
>UniRef50_Q043M4 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=2; Lactobacillus|Rep: Aldo/keto
reductase of diketogulonate reductase family -
Lactobacillus gasseri (strain ATCC 33323 / DSM 20243)
Length = 273
Score = 95.9 bits (228), Expect = 6e-19
Identities = 57/142 (40%), Positives = 78/142 (54%)
Frame = +1
Query: 103 KISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQ 282
+++LN+ IP G GT+ E+ P +++ V A E GYRLIDTA Y NE Q
Sbjct: 3 QLTLNNDVKIPIFGFGTY---------EISPDQTKQAVLSAFEEGYRLIDTAQYYQNEQQ 53
Query: 283 IGAAVRASGIPREDIFIVTKLPMDNQRDVVKQLEKSLARLNMSYVDLYLIHNPVAFNPGF 462
+G AV+ASG+ R+++FI TK D D L++SL R+ + Y DL LIH P+
Sbjct: 54 VGEAVKASGLNRDEVFITTKTMTDGYEDTKIGLDESLRRIGLDYFDLVLIHWPM------ 107
Query: 463 KGFDIVDYLDTWKGMEEAKNLG 528
G DI DTW +E A G
Sbjct: 108 -GHDI----DTWHALEAAYKAG 124
>UniRef50_Q4PDR0 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 339
Score = 95.5 bits (227), Expect = 8e-19
Identities = 53/142 (37%), Positives = 80/142 (56%)
Frame = +1
Query: 109 SLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIG 288
+LN G +P++G+G + G G + + + A++ GYR +DTA Y NE ++G
Sbjct: 9 TLNTGAKLPSVGMGCWQGQPGPG----RDNELVDALVRAIKVGYRHLDTATGYRNEAEVG 64
Query: 289 AAVRASGIPREDIFIVTKLPMDNQRDVVKQLEKSLARLNMSYVDLYLIHNPVAFNPGFKG 468
AVR SG+ R +IF+ TKL DVV++LE SL L + Y+DL+L+H P F G
Sbjct: 65 QAVRQSGVARSEIFVTTKLRPGGVHDVVQELENSLNELGIDYIDLWLLHWPQGFTKDDGG 124
Query: 469 FDIVDYLDTWKGMEEAKNLGPS 534
F + G+E K+LGP+
Sbjct: 125 FGTGESF----GLEHQKHLGPT 142
>UniRef50_Q8F1G4 Cluster: Aldehyde reductase; n=8; Bacteria|Rep:
Aldehyde reductase - Leptospira interrogans
Length = 278
Score = 95.1 bits (226), Expect = 1e-18
Identities = 61/115 (53%), Positives = 72/115 (62%), Gaps = 2/115 (1%)
Frame = +1
Query: 106 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 285
I LN+G S+P LGLG + K KE K + V ALEAGYR IDTA +Y NE +
Sbjct: 12 IMLNNGISMPILGLGVW---KTKSGKECK-----EAVLNALEAGYRHIDTARIYDNEVDV 63
Query: 286 GAAVRASGIPREDIFIVTKL-PMDNQRDVV-KQLEKSLARLNMSYVDLYLIHNPV 444
G A+R SGIPR++IFI TKL D D K LE SL RL + +VDLYLIH PV
Sbjct: 64 GQAIRESGIPRKEIFITTKLWNADQGSDKTRKALENSLDRLGIDFVDLYLIHFPV 118
>UniRef50_Q03TW0 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=1; Lactobacillus brevis ATCC
367|Rep: Aldo/keto reductase of diketogulonate reductase
family - Lactobacillus brevis (strain ATCC 367 / JCM
1170)
Length = 293
Score = 95.1 bits (226), Expect = 1e-18
Identities = 56/143 (39%), Positives = 81/143 (56%), Gaps = 2/143 (1%)
Frame = +1
Query: 106 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 285
+ +N+G+ IP LGLG F + E D++ +KWAL AGYR IDTAA Y NE +
Sbjct: 14 LPMNNGHQIPQLGLGVF----QVDNAE----DTKNAIKWALAAGYRHIDTAAYYGNEQWV 65
Query: 286 GAAVRASGIPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIHNPVAFNPG 459
G A+R S +PR+ IF+ +KL + + +++L +L + Y+DLYLIH P PG
Sbjct: 66 GEAIRESDVPRDQIFVTSKLWNSVRGYDETQAAFQETLDKLGLDYLDLYLIHWPA---PG 122
Query: 460 FKGFDIVDYLDTWKGMEEAKNLG 528
YLD+W+ ME+ G
Sbjct: 123 --------YLDSWRAMEDLYKAG 137
>UniRef50_Q10494 Cluster: Probable oxidoreductase C26F1.07; n=2;
Schizosaccharomyces pombe|Rep: Probable oxidoreductase
C26F1.07 - Schizosaccharomyces pombe (Fission yeast)
Length = 321
Score = 95.1 bits (226), Expect = 1e-18
Identities = 52/119 (43%), Positives = 74/119 (62%), Gaps = 2/119 (1%)
Frame = +1
Query: 109 SLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIG 288
+L DG+ IP LGLGT+ +P ++ VK AL+ GYR ID AA+Y NED++G
Sbjct: 17 TLADGSKIPGLGLGTWRS---------EPNQTKNAVKTALQYGYRHIDAAAIYGNEDEVG 67
Query: 289 AAVRASGIPREDIFIVTKLPMDNQ--RDVVKQLEKSLARLNMSYVDLYLIHNPVAFNPG 459
++ SG+PR+DI++ +KL + V K LEK+L L + Y+D YLIH PV+F G
Sbjct: 68 DGIKESGVPRKDIWVTSKLWCNAHAPEAVPKALEKTLKDLKLDYLDEYLIHWPVSFKTG 126
>UniRef50_A7RRF6 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 275
Score = 93.9 bits (223), Expect = 2e-18
Identities = 52/118 (44%), Positives = 73/118 (61%), Gaps = 2/118 (1%)
Frame = +1
Query: 97 ASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNE 276
+S +L+DG IP GLG + DEK K+ V WALE GYR+IDTAA Y NE
Sbjct: 4 SSTRTLSDGYKIPRFGLGLY-DLDEKHTKQA--------VLWALENGYRMIDTAASYNNE 54
Query: 277 DQIGAAVRASGIPREDIFIVTKLPMDNQ--RDVVKQLEKSLARLNMSYVDLYLIHNPV 444
++G A+R S +PR ++++VTK+ + +K ++SL+ L + YVDLYLIH PV
Sbjct: 55 KRVGEALRESAVPRSEVYLVTKVYHTDHGYEKTMKAYDRSLSALGVDYVDLYLIHFPV 112
>UniRef50_Q927P9 Cluster: Lin2739 protein; n=12; Bacteria|Rep:
Lin2739 protein - Listeria innocua
Length = 283
Score = 93.5 bits (222), Expect = 3e-18
Identities = 47/114 (41%), Positives = 72/114 (63%), Gaps = 2/114 (1%)
Frame = +1
Query: 106 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 285
+ LN+G +P LG GT+ D G++E+ VK A+ AGYR IDTA Y+NE+ +
Sbjct: 4 VKLNNGIEVPILGFGTYQITDA--------GEAEQAVKEAIAAGYRHIDTAQSYMNEEAV 55
Query: 286 GAAVRASGIPREDIFIVTKLPMDN--QRDVVKQLEKSLARLNMSYVDLYLIHNP 441
G + ASG+ R+++FI TK+ ++N + V+ ++SL RL + Y+DL LIH P
Sbjct: 56 GRGIAASGVDRKELFITTKIWVENVSYKGVMSSFDRSLKRLGLDYIDLLLIHQP 109
>UniRef50_Q3CZS2 Cluster: Oxidoreductase, aldo/keto reductase
family; n=2; Streptococcus agalactiae|Rep:
Oxidoreductase, aldo/keto reductase family -
Streptococcus agalactiae H36B
Length = 245
Score = 93.5 bits (222), Expect = 3e-18
Identities = 50/113 (44%), Positives = 74/113 (65%), Gaps = 2/113 (1%)
Frame = +1
Query: 112 LNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGA 291
LN+G IP+LG G F D P + E+ V AL+ GYRLIDTA+ YLNE+ +G
Sbjct: 9 LNNGVKIPSLGFGVFQIDD--------PLECEQSVLDALQVGYRLIDTASGYLNEEAVGR 60
Query: 292 AVRASGIPREDIFIVTKLPMD--NQRDVVKQLEKSLARLNMSYVDLYLIHNPV 444
A++ SGIPR++IF+VTKL + ++ ++++L RL + Y++LYLIH P+
Sbjct: 61 AIKKSGIPRKEIFVVTKLWIQDASEEKAGPAIDRALKRLQLDYINLYLIHQPM 113
>UniRef50_Q2U219 Cluster: Aldo/keto reductase family proteins; n=6;
Pezizomycotina|Rep: Aldo/keto reductase family proteins
- Aspergillus oryzae
Length = 294
Score = 93.5 bits (222), Expect = 3e-18
Identities = 44/113 (38%), Positives = 73/113 (64%)
Frame = +1
Query: 103 KISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQ 282
++ LND SIP LG GT + ++ + + + +K A+ GYR +D A +Y E +
Sbjct: 11 RVKLNDNVSIPILGYGTGTAWYKQAGDDSVNRELVEAIKTAIRLGYRHLDGAEVYGTEAE 70
Query: 283 IGAAVRASGIPREDIFIVTKLPMDNQRDVVKQLEKSLARLNMSYVDLYLIHNP 441
+G A++ SGIPRE++F+ TK+ + N D+ +++SL +L ++YVDLYLIH+P
Sbjct: 71 LGVAIKESGIPREELFVTTKV-ITNIADIPSAIDQSLRKLQLNYVDLYLIHSP 122
>UniRef50_Q8ZI40 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=74; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase
A - Yersinia pestis
Length = 277
Score = 93.5 bits (222), Expect = 3e-18
Identities = 51/112 (45%), Positives = 72/112 (64%)
Frame = +1
Query: 106 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 285
I L DG +P LGLG + Q ++ ++E V ALE GYR IDTAA+Y NE+ +
Sbjct: 7 IKLYDGRLMPQLGLGVW-------QASIQ--ETELAVSKALEVGYRSIDTAAIYKNEEGV 57
Query: 286 GAAVRASGIPREDIFIVTKLPMDNQRDVVKQLEKSLARLNMSYVDLYLIHNP 441
G A++A+ + R+++FI TKL D+Q + + LE SL +L + YVDLYLIH P
Sbjct: 58 GKALKAAAVARDELFITTKLWNDDQHNPQQALETSLQKLQLDYVDLYLIHWP 109
>UniRef50_Q7N0E4 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=2; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase
A - Photorhabdus luminescens subsp. laumondii
Length = 292
Score = 92.3 bits (219), Expect = 8e-18
Identities = 51/112 (45%), Positives = 68/112 (60%)
Frame = +1
Query: 106 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 285
I L DGN +P LGLG++ D++ + + AL+ GYR IDTAA+Y NE +
Sbjct: 7 IRLADGNHMPQLGLGSWASDDQQIAETIHA---------ALDIGYRAIDTAAIYNNEKGV 57
Query: 286 GAAVRASGIPREDIFIVTKLPMDNQRDVVKQLEKSLARLNMSYVDLYLIHNP 441
G A++ + IPREDIF+ TKL D D L +SL +L + YVDLYLIH P
Sbjct: 58 GNALQETDIPREDIFVTTKLWNDRHLDARAALTESLEKLQLDYVDLYLIHWP 109
>UniRef50_A7SGW6 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 264
Score = 92.3 bits (219), Expect = 8e-18
Identities = 50/121 (41%), Positives = 77/121 (63%), Gaps = 2/121 (1%)
Frame = +1
Query: 85 GGGKASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAAL 264
G G +S ++LNDG +P GLG F E G ++V +AL+ GYR++DTA +
Sbjct: 6 GEGLSSFVTLNDGRKMPLFGLGVFRL--ETGCEDV--------CLFALKNGYRMLDTADI 55
Query: 265 YLNEDQIGAAVRASGIPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIHN 438
Y NE ++G+AVR SG+ REDI++ TKL + + +K ++S+ +L++ YVDL+LIH
Sbjct: 56 YQNEKEVGSAVRKSGLKREDIYVTTKLKPSEEGHSNALKYAKESIKKLDIGYVDLFLIHT 115
Query: 439 P 441
P
Sbjct: 116 P 116
>UniRef50_Q96UH3 Cluster: Aldehyde reductase; n=13;
Pezizomycotina|Rep: Aldehyde reductase - Coccidioides
posadasii
Length = 314
Score = 92.3 bits (219), Expect = 8e-18
Identities = 61/151 (40%), Positives = 84/151 (55%), Gaps = 12/151 (7%)
Frame = +1
Query: 112 LNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGA 291
LN G IPA+G GT+ DE Q++ V AL AGYR IDTAA+Y E IG
Sbjct: 10 LNTGEDIPAIGFGTWQ--DENAQEDA--------VLTALSAGYRHIDTAAVYGTEKAIGR 59
Query: 292 AVRASGIPREDIFIVTKLPMDNQR--DVVKQLEKSLARLNMSYVDLYLIHNPVAFNPGFK 465
A+ S + R+++FI +KL + R DV + +++SL L + Y+DLYL+H P AF PG
Sbjct: 60 ALARSRLSRDELFITSKLWNNKHRPEDVEQAIDQSLKNLEIDYLDLYLMHWPAAFAPGDD 119
Query: 466 GFD----------IVDYLDTWKGMEEAKNLG 528
F +DY+DT+K ME+ G
Sbjct: 120 MFPKDSQGNSKTVDIDYVDTYKAMEKLVKSG 150
>UniRef50_Q2UGR1 Cluster: Aldo/keto reductase family proteins; n=2;
Ascomycota|Rep: Aldo/keto reductase family proteins -
Aspergillus oryzae
Length = 323
Score = 92.3 bits (219), Expect = 8e-18
Identities = 53/115 (46%), Positives = 70/115 (60%), Gaps = 2/115 (1%)
Frame = +1
Query: 112 LNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGA 291
LN G +IPA+GLGT+L KP + E V+ AL AGYR ID AA Y NE+++G
Sbjct: 9 LNSGYNIPAIGLGTWLS---------KPHEVENAVEAALRAGYRHIDAAACYQNENEVGN 59
Query: 292 AVRASGIPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIHNPVAF 450
+ SG+PR+ IFI +KL + V + + K+L L Y+DLYLIH PVAF
Sbjct: 60 GWKKSGVPRDQIFITSKLWNTHHHPEHVEEAVNKTLKDLQTDYLDLYLIHWPVAF 114
>UniRef50_Q9ZBW7 Cluster: Putative oxidoreductase; n=2;
Actinomycetales|Rep: Putative oxidoreductase -
Streptomyces coelicolor
Length = 277
Score = 91.5 bits (217), Expect = 1e-17
Identities = 56/142 (39%), Positives = 80/142 (56%), Gaps = 2/142 (1%)
Frame = +1
Query: 94 KASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN 273
K I LN+G +P LG G + +V D++ V ALEAGYR IDTAA+Y N
Sbjct: 4 KVPPIILNNGVEMPQLGFGVW---------QVPDDDAQTAVALALEAGYRSIDTAAIYGN 54
Query: 274 EDQIGAAVRASGIPREDIFIVTKLPMDNQ--RDVVKQLEKSLARLNMSYVDLYLIHNPVA 447
E+ G A+ ASG+ RED+F+ TKL +Q ++ + S+A+L + Y+DLYLIH P+
Sbjct: 55 EEGTGRAIAASGLAREDLFVTTKLWNSDQGYDSTLRAFDTSMAKLGLEYLDLYLIHWPMP 114
Query: 448 FNPGFKGFDIVDYLDTWKGMEE 513
Y+DT+K E+
Sbjct: 115 AKE--------RYVDTYKAFEK 128
>UniRef50_Q890A0 Cluster: Oxidoreductase; n=6; Lactobacillales|Rep:
Oxidoreductase - Lactobacillus plantarum
Length = 282
Score = 91.5 bits (217), Expect = 1e-17
Identities = 53/136 (38%), Positives = 79/136 (58%), Gaps = 3/136 (2%)
Frame = +1
Query: 112 LNDGNSIPALGLGTFLGFDEKGQKEVKPGDSE-KPVKWALEAGYRLIDTAALYLNEDQIG 288
L +G +IP + GT+ ++ G++ + V+ AL AGYR IDTA Y NE +G
Sbjct: 10 LANGVNIPKVAFGTW---------QIPGGEATYQAVRAALAAGYRHIDTALAYQNEASVG 60
Query: 289 AAVRASGIPREDIFIVTKLPMDNQ--RDVVKQLEKSLARLNMSYVDLYLIHNPVAFNPGF 462
A+R SGIPRE IF+ TKLP + + + + ++SL L + YVDLYL+H P +
Sbjct: 61 QAIRDSGIPREQIFVTTKLPAETKSYQGALNDFDRSLKNLGLDYVDLYLVHAPWPWGQVG 120
Query: 463 KGFDIVDYLDTWKGME 510
+ +D + LD W+ ME
Sbjct: 121 RVYDEAN-LDVWQAME 135
>UniRef50_P15121 Cluster: Aldose reductase; n=72; Eumetazoa|Rep:
Aldose reductase - Homo sapiens (Human)
Length = 316
Score = 91.5 bits (217), Expect = 1e-17
Identities = 60/160 (37%), Positives = 91/160 (56%), Gaps = 16/160 (10%)
Frame = +1
Query: 97 ASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNE 276
AS++ LN+G +P LGLGT+ + PG + VK A++ GYR ID A +Y NE
Sbjct: 2 ASRLLLNNGAKMPILGLGTW---------KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNE 52
Query: 277 DQIGAAV----RASGIPREDIFIVTKLPMD-NQRDVVK-QLEKSLARLNMSYVDLYLIHN 438
+++G A+ R + RE++FIV+KL +++ +VK +K+L+ L + Y+DLYLIH
Sbjct: 53 NEVGVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHW 112
Query: 439 PVAFNPGFKGFDI----------VDYLDTWKGMEEAKNLG 528
P F PG + F + + LDTW MEE + G
Sbjct: 113 PTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEG 152
>UniRef50_Q0VGY1 Cluster: 3-alpha-hydroxysteroid dehydrogenase;
n=13; Tetrapoda|Rep: 3-alpha-hydroxysteroid
dehydrogenase - Xenopus tropicalis (Western clawed frog)
(Silurana tropicalis)
Length = 324
Score = 91.1 bits (216), Expect = 2e-17
Identities = 60/161 (37%), Positives = 84/161 (52%), Gaps = 16/161 (9%)
Frame = +1
Query: 94 KASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN 273
K S + LNDG+ +P +G GT+ K K + +E+ K A++ GYR ID A LY N
Sbjct: 5 KDSYVELNDGHKMPVIGFGTYA--PPKFPKSL----AEEGTKVAIDVGYRHIDCAFLYGN 58
Query: 274 EDQIGAAVRA----SGIPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIH 435
E+++G A+RA + RED+F KL V LEKSL L + Y+DL++IH
Sbjct: 59 EEEVGRAIRAKIADGTVKREDVFYTGKLWSTSHTPERVRPALEKSLKDLQLDYMDLFIIH 118
Query: 436 NPVAFNPGFKGFDI----------VDYLDTWKGMEEAKNLG 528
P+ F PG F D DTWK +E+ K+ G
Sbjct: 119 MPMEFKPGDDLFPADENGKFIYHNTDLRDTWKALEKCKDAG 159
>UniRef50_Q8Y463 Cluster: Lmo2592 protein; n=40; Bacteria|Rep:
Lmo2592 protein - Listeria monocytogenes
Length = 283
Score = 91.1 bits (216), Expect = 2e-17
Identities = 47/114 (41%), Positives = 71/114 (62%), Gaps = 2/114 (1%)
Frame = +1
Query: 106 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 285
+ LN+G +P LG GT+ D ++E VK A++AGYR IDTA Y+NE+ +
Sbjct: 4 VKLNNGVEVPILGFGTYQITDA--------AEAEHAVKDAIKAGYRHIDTAQSYMNEEAV 55
Query: 286 GAAVRASGIPREDIFIVTKLPMDN--QRDVVKQLEKSLARLNMSYVDLYLIHNP 441
G + ASG+ R+++FI TK+ ++N + V+ ++SL RL + YVDL LIH P
Sbjct: 56 GRGIAASGVDRKELFITTKIWVENVSYKGVMSSFDRSLKRLGLDYVDLLLIHQP 109
>UniRef50_A6W8E7 Cluster: 2,5-didehydrogluconate reductase; n=3;
Actinomycetales|Rep: 2,5-didehydrogluconate reductase -
Kineococcus radiotolerans SRS30216
Length = 289
Score = 90.6 bits (215), Expect = 2e-17
Identities = 56/143 (39%), Positives = 84/143 (58%), Gaps = 2/143 (1%)
Frame = +1
Query: 106 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 285
I LNDG IP LG G F +++PGD+ + VK AL+ GYR IDTA +Y NE ++
Sbjct: 15 ILLNDGREIPQLGFGVF---------QIEPGDTAQAVKTALDLGYRHIDTAQMYGNEAEV 65
Query: 286 GAAVRASGIPREDIFIVTKLPMD-NQRDVV-KQLEKSLARLNMSYVDLYLIHNPVAFNPG 459
+ SG+PR++I++ +KL ++ D K ++ S+ +L +DLYLIH P+ P
Sbjct: 66 AQGIADSGVPRDEIWVTSKLNNGFHEPDAARKAVDDSVEKLR-GPIDLYLIHWPL---PT 121
Query: 460 FKGFDIVDYLDTWKGMEEAKNLG 528
G D++ TWK +EEA+ G
Sbjct: 122 LYG---GDFVSTWKVLEEARAAG 141
>UniRef50_Q5FLI5 Cluster: Aldehyde reductase; n=2; Bacteria|Rep:
Aldehyde reductase - Lactobacillus acidophilus
Length = 278
Score = 90.2 bits (214), Expect = 3e-17
Identities = 51/137 (37%), Positives = 81/137 (59%), Gaps = 2/137 (1%)
Frame = +1
Query: 106 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 285
++LN+G +P LG G + D+ Q +++ V+ LE GYRL+DTA +Y NE +
Sbjct: 5 VTLNNGIKMPRLGFGVYQ-IDDLAQ-------AQQVVEDGLEVGYRLVDTAQIYGNEQAV 56
Query: 286 GAAVRASGIPREDIFIVTKLPMDN--QRDVVKQLEKSLARLNMSYVDLYLIHNPVAFNPG 459
G A++ S +PREDIFI +K+ +D+ + +K + S+ +L + Y+DLYLIH P +N
Sbjct: 57 GDAIKHSNVPREDIFITSKIWVDDYGYDNTLKAFDDSMKKLQLDYIDLYLIHKP--YN-- 112
Query: 460 FKGFDIVDYLDTWKGME 510
DY TW+ +E
Sbjct: 113 -------DYYGTWRALE 122
>UniRef50_A7BA05 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 292
Score = 90.2 bits (214), Expect = 3e-17
Identities = 58/141 (41%), Positives = 75/141 (53%), Gaps = 2/141 (1%)
Frame = +1
Query: 112 LNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGA 291
L G+ IP LG GT+ +V P D+ V ALE GYR IDTA +Y NE ++GA
Sbjct: 21 LPTGSPIPVLGFGTY---------KVAPEDTYDAVSRALEVGYRHIDTAQMYGNEAEVGA 71
Query: 292 AVRASGIPREDIFIVTKLPMDNQRD--VVKQLEKSLARLNMSYVDLYLIHNPVAFNPGFK 465
A+ ASGI RED+FI TK+ N + +SL L YVDL L+H P+ P
Sbjct: 72 ALEASGIAREDLFITTKVDNSNHEPDRAAASIRRSLEDLRTDYVDLLLVHWPL---PTLY 128
Query: 466 GFDIVDYLDTWKGMEEAKNLG 528
G D+ W +E+A N G
Sbjct: 129 GGDVA---LPWPALEDAFNAG 146
>UniRef50_Q5KI95 Cluster: Aldo-keto reductase, putative; n=14;
Dikarya|Rep: Aldo-keto reductase, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 353
Score = 90.2 bits (214), Expect = 3e-17
Identities = 49/119 (41%), Positives = 69/119 (57%)
Frame = +1
Query: 100 SKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNED 279
+ LN G SIPA+GLGT+ + K G+ + V AL+AGYR ID A Y NED
Sbjct: 37 TSFKLNTGASIPAIGLGTW---------QAKAGEVRQAVAHALKAGYRHIDGALCYQNED 87
Query: 280 QIGAAVRASGIPREDIFIVTKLPMDNQRDVVKQLEKSLARLNMSYVDLYLIHNPVAFNP 456
++G ++ SG+PR +IF+ +K+ V + L+ +L L Y+DLYLIH PV P
Sbjct: 88 EVGLGIKDSGVPRSEIFLTSKVWSSYHDRVEECLDTTLKSLQTDYLDLYLIHWPVRLAP 146
>UniRef50_P14550 Cluster: Alcohol dehydrogenase [NADP+]; n=44;
Bilateria|Rep: Alcohol dehydrogenase [NADP+] - Homo
sapiens (Human)
Length = 325
Score = 90.2 bits (214), Expect = 3e-17
Identities = 59/155 (38%), Positives = 85/155 (54%), Gaps = 17/155 (10%)
Frame = +1
Query: 97 ASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNE 276
AS + L+ G +P +GLGT+ + +PG + VK+AL GYR ID AA+Y NE
Sbjct: 3 ASCVLLHTGQKMPLIGLGTW---------KSEPGQVKAAVKYALSVGYRHIDCAAIYGNE 53
Query: 277 DQIGAAVR-----ASGIPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIH 435
+IG A++ +PRE++F+ +KL + DV L K+LA L + Y+DLYL+H
Sbjct: 54 PEIGEALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMH 113
Query: 436 NPVAF----NP------GFKGFDIVDYLDTWKGME 510
P AF NP G +D Y +TWK +E
Sbjct: 114 WPYAFERGDNPFPKNADGTICYDSTHYKETWKALE 148
>UniRef50_P45376 Cluster: Aldose reductase; n=21; Bilateria|Rep:
Aldose reductase - Mus musculus (Mouse)
Length = 316
Score = 89.8 bits (213), Expect = 4e-17
Identities = 58/160 (36%), Positives = 88/160 (55%), Gaps = 16/160 (10%)
Frame = +1
Query: 97 ASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNE 276
AS + LN+G +P LGLGT+ + PG + VK A++ GYR ID A +Y NE
Sbjct: 2 ASHLELNNGTKMPTLGLGTW---------KSPPGQVTEAVKVAIDLGYRHIDCAQVYQNE 52
Query: 277 DQIGAA----VRASGIPREDIFIVTKLPMD-NQRDVVK-QLEKSLARLNMSYVDLYLIHN 438
++G A ++ + R+D+FIV+KL + + +VK +K+L+ L + Y+DLYLIH
Sbjct: 53 KEVGVALQEKLKEQVVKRQDLFIVSKLWCTFHDKSMVKGAFQKTLSDLQLDYLDLYLIHW 112
Query: 439 PVAFNPGFKGFDI----------VDYLDTWKGMEEAKNLG 528
P F PG F + D++DTW ME+ + G
Sbjct: 113 PTGFKPGPDYFPLDASGNVIPSDTDFVDTWTAMEQLVDEG 152
>UniRef50_A2R6Z3 Cluster: Catalytic activity: an alcohol + NADP(+)
<=> an aldehyde + NADPH; n=9; Pezizomycotina|Rep:
Catalytic activity: an alcohol + NADP(+) <=> an aldehyde
+ NADPH - Aspergillus niger
Length = 345
Score = 89.4 bits (212), Expect = 5e-17
Identities = 61/153 (39%), Positives = 83/153 (54%), Gaps = 14/153 (9%)
Frame = +1
Query: 112 LNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGA 291
LN G +PA+GLGT+ + K + V AL+ GYR ID AA+Y NE ++G
Sbjct: 9 LNTGYDMPAVGLGTW---------QSKKDEVRDAVIAALKCGYRHIDAAAVYGNEQEVGD 59
Query: 292 AVRASGIPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIHNPVAF----- 450
+R SG+PRE+IF+ +KL + +V + ++KSLA L Y+DLYLIH PVAF
Sbjct: 60 GMRLSGVPREEIFLTSKLWNTHHHPENVEEAVDKSLADLQTDYLDLYLIHWPVAFRYSTT 119
Query: 451 -----NPGFKGFDIVD--YLDTWKGMEEAKNLG 528
N D+VD DTW ME+ G
Sbjct: 120 TIQPVNEQTGLIDVVDVPIKDTWAAMEKLVEKG 152
>UniRef50_P27800 Cluster: Aldehyde reductase 1; n=18; root|Rep:
Aldehyde reductase 1 - Sporobolomyces salmonicolor
Length = 323
Score = 89.0 bits (211), Expect = 7e-17
Identities = 48/118 (40%), Positives = 73/118 (61%), Gaps = 2/118 (1%)
Frame = +1
Query: 109 SLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIG 288
+LN G S+ +G GT+ + PG+ + VK A+E GYR +D A +Y N+ ++G
Sbjct: 6 TLNTGASLELVGYGTW---------QAAPGEVGQGVKVAIETGYRHLDLAKVYSNQPEVG 56
Query: 289 AAVRASGIPREDIFIVTKLPMDNQR--DVVKQLEKSLARLNMSYVDLYLIHNPVAFNP 456
AA++ +G+ RED+FI +KL ++ R V L+ +L L + Y+DLYLIH PVAF P
Sbjct: 57 AAIKEAGVKREDLFITSKLWNNSHRPEQVEPALDDTLKELGLEYLDLYLIHWPVAFPP 114
>UniRef50_Q8EVS8 Cluster: Oxidoreductase; n=1; Mycoplasma
penetrans|Rep: Oxidoreductase - Mycoplasma penetrans
Length = 289
Score = 88.6 bits (210), Expect = 9e-17
Identities = 48/128 (37%), Positives = 75/128 (58%)
Frame = +1
Query: 106 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 285
I+LN+GN IP++G G F ++ ++ VK A+ GYRLIDTA Y NE +
Sbjct: 9 ITLNNGNKIPSIGFGVF---------QIPKEETADCVKKAISIGYRLIDTAQAYHNEKET 59
Query: 286 GAAVRASGIPREDIFIVTKLPMDNQRDVVKQLEKSLARLNMSYVDLYLIHNPVAFNPGFK 465
G ++ SG+ RE+IF+ TK+ + N + + +SL RL+ SY+DL L+H P F +K
Sbjct: 60 GLGIKLSGVKREEIFLTTKVWVSNYERCYESVIESLKRLDTSYLDLILLHQP--FGNYYK 117
Query: 466 GFDIVDYL 489
+ ++ L
Sbjct: 118 AYQDLERL 125
>UniRef50_Q6F7K7 Cluster: 2,5-diketo-D-gluconate reductase; n=20;
Bacteria|Rep: 2,5-diketo-D-gluconate reductase -
Acinetobacter sp. (strain ADP1)
Length = 297
Score = 87.8 bits (208), Expect = 2e-16
Identities = 58/141 (41%), Positives = 85/141 (60%), Gaps = 2/141 (1%)
Frame = +1
Query: 112 LNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGA 291
L+DG+SIPALG GT+ KGQ+ V + AL GYR++D+A Y NE +GA
Sbjct: 27 LHDGHSIPALGFGTYT---LKGQQGVDT------MLRALGHGYRMLDSAFNYENEGAVGA 77
Query: 292 AVRASGIPREDIFIVTKLPMDNQR--DVVKQLEKSLARLNMSYVDLYLIHNPVAFNPGFK 465
AVR SG+ R++IFI +KLP + ++ +E+SL R+ Y+DLYLIH P NP +
Sbjct: 78 AVRQSGLLRDEIFITSKLPGRHHAYDKAMETIEESLYRMQFDYLDLYLIHWP---NPQ-Q 133
Query: 466 GFDIVDYLDTWKGMEEAKNLG 528
G Y++ W+ + +A+ G
Sbjct: 134 GL----YIEAWQALIDAQKKG 150
>UniRef50_Q41E86 Cluster: 2,5-didehydrogluconate reductase; n=2;
Bacteria|Rep: 2,5-didehydrogluconate reductase -
Exiguobacterium sibiricum 255-15
Length = 274
Score = 87.8 bits (208), Expect = 2e-16
Identities = 55/138 (39%), Positives = 78/138 (56%), Gaps = 2/138 (1%)
Frame = +1
Query: 106 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 285
++LN+G +P LG G F +V + + V+ AL GYR IDTA +Y NE +
Sbjct: 4 VTLNNGLVMPQLGYGVF---------KVPEQEVYEAVREALRVGYRSIDTAMIYENEAGV 54
Query: 286 GAAVRASGIPREDIFIVTKLPMDNQ--RDVVKQLEKSLARLNMSYVDLYLIHNPVAFNPG 459
G A++ SGIPREDIF+ TK+ +Q + E SL +L + YVDLYLIH P+
Sbjct: 55 GRALKDSGIPREDIFLTTKVWNKDQGYERTLAAFETSLQKLGVDYVDLYLIHWPMP---- 110
Query: 460 FKGFDIVDYLDTWKGMEE 513
D Y+DTW+ +E+
Sbjct: 111 ----DEDLYMDTWRALEQ 124
>UniRef50_Q4Q5N9 Cluster: Prostaglandin f synthase, putative; n=7;
cellular organisms|Rep: Prostaglandin f synthase,
putative - Leishmania major
Length = 279
Score = 87.8 bits (208), Expect = 2e-16
Identities = 52/142 (36%), Positives = 76/142 (53%), Gaps = 2/142 (1%)
Frame = +1
Query: 94 KASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN 273
K + ++L++G +P LG+GT+ E K G+ +KWA+ AGYR +DTA Y N
Sbjct: 4 KCTHVTLSNGVQVPQLGIGTW---------EAKDGNEVVNIKWAVNAGYRHVDTAHYYKN 54
Query: 274 EDQIGAAVRASGIPREDIFIVTKL-PMDN-QRDVVKQLEKSLARLNMSYVDLYLIHNPVA 447
E +G + G+PR DIF+ TKL D+ + E+S L + YVDLYLIH P
Sbjct: 55 EKGVGQGISECGVPRSDIFVTTKLWNYDHGYESALAAFEQSRQALGVEYVDLYLIHWP-- 112
Query: 448 FNPGFKGFDIVDYLDTWKGMEE 513
P Y++TW+ E+
Sbjct: 113 -GPN------RSYIETWRAFEK 127
>UniRef50_UPI00015B4B22 Cluster: PREDICTED: similar to GA15457-PA;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
GA15457-PA - Nasonia vitripennis
Length = 388
Score = 87.4 bits (207), Expect = 2e-16
Identities = 65/173 (37%), Positives = 84/173 (48%), Gaps = 16/173 (9%)
Frame = +1
Query: 40 FVITTLIVHLSEATTGGGKASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVK 219
F+ +V L+ G K+ L+ G+ IPA+GLGT +K + + +
Sbjct: 4 FLGIVCLVVLAVVLPGAQAVEKLKLSSGHEIPAVGLGT---------STIKLDEMDNAIS 54
Query: 220 WALEAGYRLIDTAALYLNEDQIGAAVRA---SGIPREDIFIVTKLPMDNQR--DVVKQLE 384
ALE GYR IDTA Y NE IG ++ G REDIFI +KLP R V L+
Sbjct: 55 SALENGYRHIDTAFSYDNEAAIGKILKKWFDKGGKREDIFITSKLPSQGNRPQSVETYLK 114
Query: 385 KSLARLNMSYVDLYLIHNPVAFNPGFK--------G---FDIVDYLDTWKGME 510
+SL L + YVD+YLIH P A G G FD VD+ WK ME
Sbjct: 115 RSLKDLGLDYVDMYLIHTPFAVKEGENLSSKQDKDGNDLFDDVDHKALWKAME 167
>UniRef50_A5ZYE6 Cluster: Putative uncharacterized protein; n=1;
Ruminococcus obeum ATCC 29174|Rep: Putative
uncharacterized protein - Ruminococcus obeum ATCC 29174
Length = 263
Score = 87.4 bits (207), Expect = 2e-16
Identities = 53/135 (39%), Positives = 77/135 (57%), Gaps = 2/135 (1%)
Frame = +1
Query: 130 IPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGAAVRASG 309
+P LGLG + K ++E + A++ GYRL+DTA+ Y NE+ +G + G
Sbjct: 1 MPLLGLGLY--------KTTDAVEAEDAIAAAVQNGYRLLDTASAYKNEEFVGCGIAKCG 52
Query: 310 IPREDIFIVTKLPMDNQR--DVVKQLEKSLARLNMSYVDLYLIHNPVAFNPGFKGFDIVD 483
+PR+D+FI TK+ + QR DV ++SL RL + Y+DLYLIH PV PG
Sbjct: 53 VPRKDLFITTKIWNNAQRLGDVEGAFQRSLDRLGLDYIDLYLIHWPV---PGC------- 102
Query: 484 YLDTWKGMEEAKNLG 528
+L+TWK ME+ G
Sbjct: 103 FLNTWKDMEKILESG 117
>UniRef50_P51857 Cluster: 3-oxo-5-beta-steroid 4-dehydrogenase (EC
1.3.1.3) (Delta(4)-3- ketosteroid 5-beta-reductase);
n=124; cellular organisms|Rep: 3-oxo-5-beta-steroid
4-dehydrogenase (EC 1.3.1.3) (Delta(4)-3- ketosteroid
5-beta-reductase) - Homo sapiens (Human)
Length = 326
Score = 87.4 bits (207), Expect = 2e-16
Identities = 55/125 (44%), Positives = 74/125 (59%), Gaps = 6/125 (4%)
Frame = +1
Query: 103 KISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQ 282
+I L+DGNSIP +GLGT+ K G VK A++ GYR ID A +Y NE +
Sbjct: 9 RIPLSDGNSIPIIGLGTY-----SEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHE 63
Query: 283 IGAAVR---ASG-IPREDIFIVTKLPMDNQ-RDVVK-QLEKSLARLNMSYVDLYLIHNPV 444
+G A+R A G + REDIF KL N ++V+ LE++L L + YVDLY+I P+
Sbjct: 64 VGEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPM 123
Query: 445 AFNPG 459
AF PG
Sbjct: 124 AFKPG 128
>UniRef50_Q5BKE9 Cluster: LOC594893 protein; n=5; Xenopus
tropicalis|Rep: LOC594893 protein - Xenopus tropicalis
(Western clawed frog) (Silurana tropicalis)
Length = 345
Score = 87.0 bits (206), Expect = 3e-16
Identities = 64/176 (36%), Positives = 88/176 (50%), Gaps = 31/176 (17%)
Frame = +1
Query: 94 KASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPG---------------DSEKPVKWAL 228
+ + I L+DG +P + GTF F G + PG D K AL
Sbjct: 5 QGASIQLHDGRWMPVVAFGTFYPFTFPGDSQANPGHCAGTKHGTEKSFIDDVRVATKMAL 64
Query: 229 EAGYRLIDTAALYLNEDQIGAAVR---ASG-IPREDIFIVTKL-PMDNQRDVVKQ-LEKS 390
+ GYR +D A LY +E +G A R A G + RED+F +KL +Q +V+ LEK+
Sbjct: 65 DLGYRHVDGAFLYSSETGVGQAFREKFADGTLKREDLFYTSKLWNTFHQPHLVRPALEKT 124
Query: 391 LARLNMSYVDLYLIHNPVAFNP----------GFKGFDIVDYLDTWKGMEEAKNLG 528
L+ L M YVDLYLIH P++F P G FD D L TW+ +EE ++ G
Sbjct: 125 LSFLQMDYVDLYLIHMPMSFKPAEELFPKNEDGTCAFDQPDLLQTWQALEECRDAG 180
>UniRef50_A2UAH0 Cluster: Aldo/keto reductase; n=1; Bacillus
coagulans 36D1|Rep: Aldo/keto reductase - Bacillus
coagulans 36D1
Length = 273
Score = 87.0 bits (206), Expect = 3e-16
Identities = 54/143 (37%), Positives = 81/143 (56%), Gaps = 4/143 (2%)
Frame = +1
Query: 112 LNDGNSIPALGLGTFLGFDEKGQKEVKPGDSE-KPVKWALEAGYRLIDTAALYLNEDQIG 288
L +G +IP +GLGT+ +V G++ V +AL+ GYR IDTA Y NE+ +G
Sbjct: 10 LENGVAIPKIGLGTW---------QVPNGETTYHAVSFALKNGYRHIDTAYAYHNEESVG 60
Query: 289 AAVRASGIPREDIFIVTKLPMD--NQRDVVKQLEKSLARLNMSYVDLYLIHNPVAFNPGF 462
AVR SGI R DIF+ +KLP + + +K ++++ + +DLYLIH P ++
Sbjct: 61 KAVRDSGIDRRDIFVTSKLPAEIKSYDKALKTFDETMGNFGLEQLDLYLIHAPWPWSE-- 118
Query: 463 KGFDIV-DYLDTWKGMEEAKNLG 528
KG D + ++ WK MEE G
Sbjct: 119 KGADYTKENIEVWKAMEEIYESG 141
>UniRef50_Q8ET73 Cluster: 2,5-diketo-D-gluconate reductase; n=12;
Bacteria|Rep: 2,5-diketo-D-gluconate reductase -
Oceanobacillus iheyensis
Length = 280
Score = 86.6 bits (205), Expect = 4e-16
Identities = 56/144 (38%), Positives = 79/144 (54%), Gaps = 3/144 (2%)
Frame = +1
Query: 106 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 285
++L+DG +IP +G GT+ + D + + A++ GYRLIDTA Y NE +
Sbjct: 8 VTLHDGLTIPKVGFGTY---------RLNGNDGVQAINNAIDHGYRLIDTAYNYENEGTV 58
Query: 286 GAAVRASGIPREDIFIVTKLP--MDNQRDVVKQLEKSLARLNMSYVDLYLIHNPVAFNPG 459
G AVR S PRE + I +KLP + V +++SL R N+ Y DLYLIH P NP
Sbjct: 59 GEAVRRSSTPREQLLITSKLPGRYHHYDKAVTTIQESLYRANLDYYDLYLIHWP---NP- 114
Query: 460 FKGFDIVD-YLDTWKGMEEAKNLG 528
I D Y++ W+ + EAK G
Sbjct: 115 -----IQDIYVEAWQALIEAKRRG 133
>UniRef50_Q7JVH6 Cluster: LD24696p; n=2; Sophophora|Rep: LD24696p -
Drosophila melanogaster (Fruit fly)
Length = 311
Score = 86.6 bits (205), Expect = 4e-16
Identities = 60/157 (38%), Positives = 85/157 (54%), Gaps = 13/157 (8%)
Frame = +1
Query: 97 ASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNE 276
A I LN+G +P LGLGT+ F+ D+ + AL+ GYR +DTA +Y NE
Sbjct: 5 APTIRLNNGREMPTLGLGTWKSFES---------DAYHSTRHALDVGYRHLDTAFVYENE 55
Query: 277 DQIGAAVR---ASG-IPREDIFIVTKLP--MDNQRDVVKQLEKSLARLNMSYVDLYLIHN 438
++G A+ A G + RE++F+ TKL + V + SL+ L + YVDLYL+H
Sbjct: 56 AEVGQAISEKIAEGVVTREEVFVTTKLGGIHHDPALVERACRLSLSNLGLEYVDLYLMHM 115
Query: 439 PVA--FN-----PGFKGFDIVDYLDTWKGMEEAKNLG 528
PV F+ G VDYLDTW+ ME+ +LG
Sbjct: 116 PVGQKFHNDSNVHGTLELTDVDYLDTWREMEKLVDLG 152
>UniRef50_Q02198 Cluster: Morphine 6-dehydrogenase; n=5;
Bacteria|Rep: Morphine 6-dehydrogenase - Pseudomonas
putida
Length = 296
Score = 86.6 bits (205), Expect = 4e-16
Identities = 49/119 (41%), Positives = 70/119 (58%), Gaps = 2/119 (1%)
Frame = +1
Query: 91 GKASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYL 270
GK+ I+LN+G +PALGLG F E ++ + A+ +GYRLIDTA Y
Sbjct: 3 GKSPLINLNNGVKMPALGLGVFAASAE---------ETASAIASAISSGYRLIDTARSYN 53
Query: 271 NEDQIGAAVRASGIPREDIFIVTKL-PMD-NQRDVVKQLEKSLARLNMSYVDLYLIHNP 441
NE Q+G +R SG+ R ++F+ TKL D ++ ++SL RL + YVDLYL+H P
Sbjct: 54 NEAQVGEGIRNSGVDRAEMFVTTKLFNCDYGYERALRAFDESLGRLGLDYVDLYLLHWP 112
>UniRef50_Q7WSY4 Cluster: Putative aldo-keto reductase; n=1;
Propionibacterium freudenreichii subsp. shermanii|Rep:
Putative aldo-keto reductase - Propionibacterium
freudenreichii subsp. shermanii
Length = 280
Score = 86.2 bits (204), Expect = 5e-16
Identities = 55/143 (38%), Positives = 81/143 (56%), Gaps = 2/143 (1%)
Frame = +1
Query: 106 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 285
+ L+ G +P LG+GT+ +K + V A+E GYRL+DTA Y NE+ +
Sbjct: 11 VELSGGTRMPMLGMGTW---------PLKGEECRAAVASAIEQGYRLVDTAEAYGNEEAV 61
Query: 286 GAAVRASGIPREDIFIVTKLPMD--NQRDVVKQLEKSLARLNMSYVDLYLIHNPVAFNPG 459
G AVR +G R +IF+ TK +++ V + LE SL RL + YVDL+L+H P+ PG
Sbjct: 62 GKAVREAGPDRAEIFVTTKFSKQWHSRKGVHEALEHSLERLGLDYVDLFLMHWPM---PG 118
Query: 460 FKGFDIVDYLDTWKGMEEAKNLG 528
+G Y+D ++GM E K G
Sbjct: 119 -EG----SYVDAYRGMVELKEQG 136
>UniRef50_Q05KR9 Cluster: Benzil reductase; n=5; Bacillales|Rep:
Benzil reductase - Bacillus subtilis
Length = 276
Score = 86.2 bits (204), Expect = 5e-16
Identities = 52/138 (37%), Positives = 79/138 (57%), Gaps = 2/138 (1%)
Frame = +1
Query: 106 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 285
+ L++G +P GLG F K ++ + VK A++ GYR IDTAA+Y NE+ +
Sbjct: 9 VKLHNGVEMPWFGLGVF--------KVENGNEATESVKAAIKNGYRSIDTAAIYKNEEGV 60
Query: 286 GAAVRASGIPREDIFIVTKLPMDNQ--RDVVKQLEKSLARLNMSYVDLYLIHNPVAFNPG 459
G ++ SG+ RE++FI +K+ ++Q + EKSL RL + Y+DLYLIH P
Sbjct: 61 GIGIKESGVAREELFITSKVWNEDQGYETTLAAFEKSLERLQLDYLDLYLIHWP------ 114
Query: 460 FKGFDIVDYLDTWKGMEE 513
G D Y DTW+ +E+
Sbjct: 115 --GKD--KYKDTWRALEK 128
>UniRef50_A6VNW9 Cluster: Aldo/keto reductase precursor; n=1;
Actinobacillus succinogenes 130Z|Rep: Aldo/keto
reductase precursor - Actinobacillus succinogenes 130Z
Length = 315
Score = 85.8 bits (203), Expect = 7e-16
Identities = 48/117 (41%), Positives = 68/117 (58%), Gaps = 1/117 (0%)
Frame = +1
Query: 94 KASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN 273
K + LN+G +P +G+G + + P +EK V AL+AGYRLIDTA +Y N
Sbjct: 41 KKRTVKLNNGIEMPIIGIGVWT---------LTPEQTEKSVGEALKAGYRLIDTARMYRN 91
Query: 274 EDQIGAAVRASGIPREDIFIVTKL-PMDNQRDVVKQLEKSLARLNMSYVDLYLIHNP 441
E +G AVR SGIPRE+IFI TK+ + + + + L L+ Y+DL L+H P
Sbjct: 92 EQAVGRAVRDSGIPREEIFITTKIYGSGDYANAEAAINERLRLLDTDYIDLLLLHYP 148
>UniRef50_P15339 Cluster: 2,5-diketo-D-gluconic acid reductase B;
n=6; Actinomycetales|Rep: 2,5-diketo-D-gluconic acid
reductase B - Corynebacterium sp. (strain SHS752001)
Length = 277
Score = 85.8 bits (203), Expect = 7e-16
Identities = 51/143 (35%), Positives = 79/143 (55%), Gaps = 2/143 (1%)
Frame = +1
Query: 106 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 285
ISLNDG GLGT+ ++ + + A+++GYRL+DTA Y NE ++
Sbjct: 7 ISLNDGRPFAEPGLGTY---------NLRGDEGVAAMVAAIDSGYRLLDTAVNYENESEV 57
Query: 286 GAAVRASGIPREDIFIVTKLP--MDNQRDVVKQLEKSLARLNMSYVDLYLIHNPVAFNPG 459
G AVRAS + R+++ + +K+P + + V + SL RL + +DL LIH P NP
Sbjct: 58 GRAVRASSVDRDELIVASKIPGRQHGRAEAVDSIRGSLDRLGLDVIDLQLIHWP---NP- 113
Query: 460 FKGFDIVDYLDTWKGMEEAKNLG 528
+ +LDTW+GM +A+ G
Sbjct: 114 ----SVGRWLDTWRGMIDAREAG 132
>UniRef50_Q9X0A2 Cluster: Oxidoreductase, aldo/keto reductase
family; n=21; Bacteria|Rep: Oxidoreductase, aldo/keto
reductase family - Thermotoga maritima
Length = 286
Score = 85.4 bits (202), Expect = 9e-16
Identities = 49/119 (41%), Positives = 73/119 (61%), Gaps = 6/119 (5%)
Frame = +1
Query: 103 KISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQ 282
K++LN+G +P LG G F ++ P +E+ V A++ GYRLIDTAA Y+NE+
Sbjct: 5 KVTLNNGVEMPILGYGVF---------QIPPEKTEECVYEAIKVGYRLIDTAASYMNEEG 55
Query: 283 IGAAVRAS---GI-PREDIFIVTKLPMDN--QRDVVKQLEKSLARLNMSYVDLYLIHNP 441
+G A++ + GI RE++F+ TKL + + K EKSL +L + Y+DLYLIH P
Sbjct: 56 VGRAIKRAIDEGIVRREELFVTTKLWVSDVGYESTKKAFEKSLKKLQLEYIDLYLIHQP 114
>UniRef50_Q6CFG7 Cluster: Yarrowia lipolytica chromosome B of strain
CLIB122 of Yarrowia lipolytica; n=9; Ascomycota|Rep:
Yarrowia lipolytica chromosome B of strain CLIB122 of
Yarrowia lipolytica - Yarrowia lipolytica (Candida
lipolytica)
Length = 337
Score = 85.0 bits (201), Expect = 1e-15
Identities = 51/119 (42%), Positives = 69/119 (57%), Gaps = 3/119 (2%)
Frame = +1
Query: 109 SLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIG 288
+LN+G +IPA+GLGT+ K E G E + E GYR IDTA Y NED +G
Sbjct: 35 TLNNGKTIPAIGLGTW-----KSTTEEVAGAVECALT---EGGYRHIDTAFNYRNEDAVG 86
Query: 289 AAVRAS---GIPREDIFIVTKLPMDNQRDVVKQLEKSLARLNMSYVDLYLIHNPVAFNP 456
++ + G+ REDIF+ TK+ + V + L+ SL RL + YVD+ LIH PV NP
Sbjct: 87 LGIKRAMEKGVKREDIFVTTKIWVTYHDRVEENLDMSLERLGLDYVDMLLIHWPVPLNP 145
>UniRef50_Q7VHE1 Cluster: Putative uncharacterized protein; n=1;
Helicobacter hepaticus|Rep: Putative uncharacterized
protein - Helicobacter hepaticus
Length = 270
Score = 84.6 bits (200), Expect = 2e-15
Identities = 51/116 (43%), Positives = 72/116 (62%), Gaps = 4/116 (3%)
Frame = +1
Query: 106 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 285
++LN+G +P LGLGT+ + GQK + SE A+E GYRL D+A +Y NE ++
Sbjct: 4 LTLNNGVKMPILGLGTYSLTGKAGQKAM----SE-----AIEVGYRLFDSAQMYNNEAEL 54
Query: 286 GAAVRAS---GIPREDIFIVTKLPMDNQRDVVKQ-LEKSLARLNMSYVDLYLIHNP 441
GAA+ A+ GI RE+ FI TKL + D+ K+ +EKSL L + Y+D LIH P
Sbjct: 55 GAAINAAVKGGIKREEFFIQTKLLESSSEDLAKKSIEKSLKTLGLDYIDSLLIHMP 110
>UniRef50_Q7VG53 Cluster: Aldo-keto reductase; n=28; Bacteria|Rep:
Aldo-keto reductase - Helicobacter hepaticus
Length = 292
Score = 84.6 bits (200), Expect = 2e-15
Identities = 49/142 (34%), Positives = 78/142 (54%), Gaps = 2/142 (1%)
Frame = +1
Query: 109 SLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIG 288
+LN+GN IP LGLGT+ + E V+ A + GYR IDTA Y NE +G
Sbjct: 16 TLNNGNKIPKLGLGTW---------RIDDNVVEAAVREAFKVGYRHIDTAQAYGNERGVG 66
Query: 289 AAVRASGIPREDIFIVTKLPMD--NQRDVVKQLEKSLARLNMSYVDLYLIHNPVAFNPGF 462
AVR S I RE++FI +K+ + + + ++ SL + + ++DL LIH+P +N
Sbjct: 67 EAVRKSKIKREELFITSKIRAEYKDYKSASASIDTSLKTMKLDFIDLMLIHSPQPWNSFR 126
Query: 463 KGFDIVDYLDTWKGMEEAKNLG 528
KG + ++ + +E+A+ G
Sbjct: 127 KGDYFKENVEVYNALEDAQKAG 148
>UniRef50_Q9VHX4 Cluster: CG2767-PA; n=4; Endopterygota|Rep:
CG2767-PA - Drosophila melanogaster (Fruit fly)
Length = 329
Score = 84.6 bits (200), Expect = 2e-15
Identities = 49/122 (40%), Positives = 71/122 (58%), Gaps = 6/122 (4%)
Frame = +1
Query: 106 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 285
++ N+G +P +G+GT+ DE + E + ALEAGYR IDTA +Y NE I
Sbjct: 7 LTFNNGEKMPVIGIGTWQASDE---------EIETAIDAALEAGYRHIDTAPVYGNEKAI 57
Query: 286 GAAVR----ASGIPREDIFIVTKLPMDNQR--DVVKQLEKSLARLNMSYVDLYLIHNPVA 447
G ++ A + RE++FIVTK+P + R +V ++KSL L + YVDLYL+H P
Sbjct: 58 GRVLKRWLDAGKVKREELFIVTKVPPVSNRPHEVEPTIKKSLEDLQLDYVDLYLVHTPFT 117
Query: 448 FN 453
N
Sbjct: 118 IN 119
>UniRef50_Q17G72 Cluster: Aldo-keto reductase; n=9;
Endopterygota|Rep: Aldo-keto reductase - Aedes aegypti
(Yellowfever mosquito)
Length = 316
Score = 84.6 bits (200), Expect = 2e-15
Identities = 62/158 (39%), Positives = 82/158 (51%), Gaps = 17/158 (10%)
Frame = +1
Query: 106 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 285
I+ +G ++PALG GT+ DE + EK + ALEAGYR IDTA +YLNE I
Sbjct: 7 ITFENGTTMPALGFGTWRASDE---------EVEKALNEALEAGYRHIDTAPVYLNEKTI 57
Query: 286 GAAVR----ASGIPREDIFIVTKLPMDNQR--DVVKQLEKSLARLNMSYVDLYLIHNPVA 447
G ++ A + R+++FIVTKLP R V K L+ SL L + YVDLY +H P
Sbjct: 58 GKVLKEWMDAGKVTRDELFIVTKLPPHGTRASTVEKFLKNSLDDLQLEYVDLYHVHVPFT 117
Query: 448 FNPGFKGFDIV-----------DYLDTWKGMEEAKNLG 528
P G +V D++ WK MEE G
Sbjct: 118 V-PEVDGPFLVEDGLIVLETTTDHVALWKAMEEVYEAG 154
>UniRef50_Q5FK98 Cluster: Oxidoreductase; n=8; Lactobacillales|Rep:
Oxidoreductase - Lactobacillus acidophilus
Length = 285
Score = 84.2 bits (199), Expect = 2e-15
Identities = 56/143 (39%), Positives = 82/143 (57%), Gaps = 3/143 (2%)
Frame = +1
Query: 109 SLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIG 288
+LN+G IP +G GT+ + EV +E+ V AL GYR IDTA+ Y NED +G
Sbjct: 11 TLNNGVKIPIIGFGTW----QTPDGEV----AEESVLAALNCGYRHIDTASAYGNEDSVG 62
Query: 289 AAVRASGIPREDIFIVTKL-PMDNQRDVVKQ-LEKSLARLNMSYVDLYLIHNPVAFNPGF 462
A++ SGI R ++FI TKL D+ + K+ +++SL L + Y+D+YLIH P NP
Sbjct: 63 RAIQKSGINRHELFITTKLWNSDHGYEKTKKAIDQSLLDLKLDYLDMYLIHWP---NPSS 119
Query: 463 KGFDIVDY-LDTWKGMEEAKNLG 528
+ ++W+ MEEA G
Sbjct: 120 MRDHWAEINAESWRAMEEAVRAG 142
>UniRef50_Q2S340 Cluster: Aldehyde reductase; n=10; Bacteria|Rep:
Aldehyde reductase - Salinibacter ruber (strain DSM
13855)
Length = 321
Score = 84.2 bits (199), Expect = 2e-15
Identities = 60/164 (36%), Positives = 87/164 (53%), Gaps = 15/164 (9%)
Frame = +1
Query: 106 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 285
IS +G+ +P +GLGT+ + PG+ + V ALEAGYR +D A +Y NE ++
Sbjct: 4 ISFENGDEMPMIGLGTW---------KSPPGEVYEAVTTALEAGYRHVDCAPIYKNETEV 54
Query: 286 GAAVR----ASGIPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIHNPVA 447
GAA+ A GI R+D+++ +KL + DV LE++L+ L + +DLYLIH PVA
Sbjct: 55 GAALSDSFDAGGIRRDDVWVTSKLWNNAHHPDDVRPALEQTLSDLRLDALDLYLIHWPVA 114
Query: 448 FNP---------GFKGFDIVDYLDTWKGMEEAKNLGPS*IYRHI 552
P F + V +TW ME K G + RHI
Sbjct: 115 LQPEVDFPESPDDFVSPEAVPLTETWAAMEALKKDG---LVRHI 155
>UniRef50_O13848 Cluster: NADH/NADPH dependent indole-3-acetaldehyde
reductase AKR3C2; n=1; Schizosaccharomyces pombe|Rep:
NADH/NADPH dependent indole-3-acetaldehyde reductase
AKR3C2 - Schizosaccharomyces pombe (Fission yeast)
Length = 284
Score = 84.2 bits (199), Expect = 2e-15
Identities = 50/133 (37%), Positives = 76/133 (57%)
Frame = +1
Query: 130 IPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGAAVRASG 309
+PA G+GT L EKG+ DS VK AL AG+ ID A +Y NE+++G A++ +
Sbjct: 12 VPAYGVGTALFKKEKGEINRTIVDS---VKNALAAGFIHIDCAEVYGNEEEVGVALKEAN 68
Query: 310 IPREDIFIVTKLPMDNQRDVVKQLEKSLARLNMSYVDLYLIHNPVAFNPGFKGFDIVDYL 489
+PR +FI +K+ M N ++ + L +SL +L Y+DLYL+H+P+ F +
Sbjct: 69 VPRSKLFITSKV-MHNVDNIPEALNESLRKLGTDYLDLYLLHSPIPFYE-----KKIPIS 122
Query: 490 DTWKGMEEAKNLG 528
+ WK ME A G
Sbjct: 123 EGWKAMETALGTG 135
>UniRef50_A2QVE5 Cluster: Similarity: shows similarity to several
dehydrogenases of different specificities; n=4;
Pezizomycotina|Rep: Similarity: shows similarity to
several dehydrogenases of different specificities -
Aspergillus niger
Length = 381
Score = 84.2 bits (199), Expect = 2e-15
Identities = 52/134 (38%), Positives = 77/134 (57%), Gaps = 8/134 (5%)
Frame = +1
Query: 103 KISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQ 282
K++LN G IP LG GT+ + PG V AL+AGYR +D A +Y N+ +
Sbjct: 6 KVTLNSGAQIPQLGFGTW---------QSAPGQVGDAVYEALKAGYRHLDLATIYQNQRE 56
Query: 283 IGAAVRAS-----GIPREDIFIVTKLPMDNQRD---VVKQLEKSLARLNMSYVDLYLIHN 438
+ ++ + G+ REDIFI +KL ++Q D V K L++ LA L + Y+DLYL+H
Sbjct: 57 VAEGIKRAYKDVPGLKREDIFITSKL-WNSQHDPAVVEKALDECLAELELDYLDLYLVHW 115
Query: 439 PVAFNPGFKGFDIV 480
PV+F G + F +V
Sbjct: 116 PVSFTTGSELFPLV 129
>UniRef50_A2QL02 Cluster: Putative frameshift; n=1; Aspergillus
niger|Rep: Putative frameshift - Aspergillus niger
Length = 357
Score = 84.2 bits (199), Expect = 2e-15
Identities = 56/152 (36%), Positives = 78/152 (51%), Gaps = 12/152 (7%)
Frame = +1
Query: 109 SLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIG 288
+LN G IPALG+GTF P E+ V L+ G RLIDTA +Y E Q+G
Sbjct: 39 TLNTGAKIPALGVGTFQD----------PDSQEETVCQVLQRGMRLIDTARVYGVEQQVG 88
Query: 289 AAVRASGIPREDIFIVTKLPMD--NQRDVVKQLEKSLARLNMSYVDLYLIHNPVAFNPGF 462
++ SG+PRE+IF+ TKL + + DV + ++ SL L YVDL L+H P F G
Sbjct: 89 RGIKKSGVPREEIFLGTKLWCNDFHPDDVERAVDDSLRDLYTPYVDLLLMHYPCTFKRGE 148
Query: 463 KGF----------DIVDYLDTWKGMEEAKNLG 528
F ++DTW+ +E+ G
Sbjct: 149 DRFPRDAEGRMIHGETTFVDTWRALEKVVKTG 180
>UniRef50_A2RMU6 Cluster: Oxidoreductase, aldo/keto reductase
family; n=3; Lactococcus lactis|Rep: Oxidoreductase,
aldo/keto reductase family - Lactococcus lactis subsp.
cremoris (strain MG1363)
Length = 281
Score = 83.8 bits (198), Expect = 3e-15
Identities = 48/115 (41%), Positives = 66/115 (57%), Gaps = 1/115 (0%)
Frame = +1
Query: 103 KISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDS-EKPVKWALEAGYRLIDTAALYLNED 279
KI LNDGN IP GLG + ++ G++ E VK AL GYR IDTA Y NE
Sbjct: 4 KIVLNDGNIIPQFGLGVY---------QIPEGEATENAVKEALRLGYRHIDTAHAYQNER 54
Query: 280 QIGAAVRASGIPREDIFIVTKLPMDNQRDVVKQLEKSLARLNMSYVDLYLIHNPV 444
+G A+ +SGIP +I+I +KL + D + +E+ L LN+ +DL L+H V
Sbjct: 55 SVGRAIHSSGIPISEIWITSKLWPSDYDDASQAIERMLELLNLKQIDLLLLHQQV 109
>UniRef50_Q968S3 Cluster: Aldoketoreductase-like protein; n=1;
Orconectes limosus|Rep: Aldoketoreductase-like protein -
Orconectes limosus (Spinycheek crayfish)
Length = 336
Score = 83.8 bits (198), Expect = 3e-15
Identities = 55/123 (44%), Positives = 72/123 (58%), Gaps = 7/123 (5%)
Frame = +1
Query: 94 KASKISLNDGNSIPALGLGT-FLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYL 270
K I LN G+ IP +GLGT LG + K +E E ALE GYR D+AA Y
Sbjct: 10 KIPTILLNSGSHIPVMGLGTGSLGRNGKMSEEAVTAVLET----ALECGYRHFDSAAYYG 65
Query: 271 NEDQIGAAVR---ASG-IPREDIFIVTKLPM--DNQRDVVKQLEKSLARLNMSYVDLYLI 432
NE IG +R + G + RE++FI TKLP + ++DV + L+KSL L + YVDLYL+
Sbjct: 66 NEAIIGQVLRRWISEGKVKREELFITTKLPTRGNREKDVARFLQKSLDNLRLPYVDLYLV 125
Query: 433 HNP 441
H P
Sbjct: 126 HYP 128
>UniRef50_Q9NAI5 Cluster: Putative uncharacterized protein; n=3;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 316
Score = 83.4 bits (197), Expect = 4e-15
Identities = 55/157 (35%), Positives = 84/157 (53%), Gaps = 16/157 (10%)
Frame = +1
Query: 106 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 285
+ LN G SIPA+GLGT+ + KPG+ +K A+ AGYR ID A +Y N+ ++
Sbjct: 5 LKLNSGYSIPAIGLGTW---------QSKPGEVAAAIKTAVAAGYRHIDCAHVYQNQKEV 55
Query: 286 GAAVR----ASGIPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIHNPVA 447
G A++ + RE++FI +K+ ++ + ++ L+ L +SYVDL LIH P
Sbjct: 56 GEALKEILDEGKVKREELFITSKVWNTFHSEAKAHENIDIILSDLQLSYVDLMLIHWPQG 115
Query: 448 FNPGFKGFDI----------VDYLDTWKGMEEAKNLG 528
+ G + F VDYL+TWK E A+ G
Sbjct: 116 YAEGAELFPAGENGKMRYSDVDYLETWKAFEAAQKAG 152
>UniRef50_Q03U37 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=5; Lactobacillus|Rep: Aldo/keto
reductase of diketogulonate reductase family -
Lactobacillus brevis (strain ATCC 367 / JCM 1170)
Length = 282
Score = 83.0 bits (196), Expect = 5e-15
Identities = 49/138 (35%), Positives = 74/138 (53%), Gaps = 2/138 (1%)
Frame = +1
Query: 112 LNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGA 291
L DG +P +G GT+L D+ ++ A +AGYR+ DTA LY NED +G
Sbjct: 12 LADGRQMPVMGFGTYLLNDQPTMNTA--------IQTAWDAGYRMFDTAMLYRNEDILGP 63
Query: 292 AVRASGIPREDIFIVTKLP--MDNQRDVVKQLEKSLARLNMSYVDLYLIHNPVAFNPGFK 465
A++ G+PRE +F+ +K+ + +K +E SL RL Y+DL LIH PV +
Sbjct: 64 AIQQLGLPREGLFLTSKVAEIVQGYDQTMKAVEGSLKRLQTDYLDLLLIHWPVREH---- 119
Query: 466 GFDIVDYLDTWKGMEEAK 519
+ DTW+ +E+ K
Sbjct: 120 ------FFDTWRALEQLK 131
>UniRef50_A7CWF9 Cluster: Aldehyde reductase; n=2; Bacteria|Rep:
Aldehyde reductase - Opitutaceae bacterium TAV2
Length = 347
Score = 83.0 bits (196), Expect = 5e-15
Identities = 60/171 (35%), Positives = 87/171 (50%), Gaps = 18/171 (10%)
Frame = +1
Query: 94 KASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN 273
K + +L G +PA+G+GTF G PG+ V A E GYR D AA+Y N
Sbjct: 15 KIPQRTLASGARMPAIGMGTF------GSDHAAPGEVAASVYAAAELGYRHFDCAAVYSN 68
Query: 274 EDQIGAAVRA-----SGIPREDIFIVTKLPMDN--QRDVVKQLEKSLARLNMSYVDLYLI 432
E +IGA R +GI RED++I +KL D + DV+ EKSL L + Y+DLYLI
Sbjct: 69 EREIGATFRRILTSNTGIRREDLWITSKLWNDKHAEADVIPAFEKSLRDLGLDYLDLYLI 128
Query: 433 HNPV-----------AFNPGFKGFDIVDYLDTWKGMEEAKNLGPS*IYRHI 552
H P + +P + + +++ TW+ +E + G + RHI
Sbjct: 129 HWPFPNFHPPGCDVSSRSPDARPYIHAEFMKTWRQLETLHDRG---LVRHI 176
>UniRef50_A7ALH6 Cluster: Putative uncharacterized protein; n=1;
Parabacteroides merdae ATCC 43184|Rep: Putative
uncharacterized protein - Parabacteroides merdae ATCC
43184
Length = 301
Score = 83.0 bits (196), Expect = 5e-15
Identities = 52/119 (43%), Positives = 72/119 (60%), Gaps = 2/119 (1%)
Frame = +1
Query: 94 KASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN 273
K + LN+G +P LG+GTFL VK +E+ V A++ G+RLIDTA Y N
Sbjct: 28 KVPTVKLNNGMEMPQLGVGTFL---------VKDNAAER-VCHAIKVGFRLIDTAQGYGN 77
Query: 274 EDQIGAAVRASGIPREDIFIVTKL-PMDNQRDVVKQ-LEKSLARLNMSYVDLYLIHNPV 444
E ++G + SGI R ++FI TK+ M+ + V+Q L+KSLA L Y+DL LIH PV
Sbjct: 78 EKEVGEGICRSGIDRRELFITTKVNTMEMRGGTVRQSLDKSLADLGTDYIDLVLIHWPV 136
>UniRef50_Q23320 Cluster: Putative uncharacterized protein; n=4;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 320
Score = 83.0 bits (196), Expect = 5e-15
Identities = 61/151 (40%), Positives = 81/151 (53%), Gaps = 6/151 (3%)
Frame = +1
Query: 94 KASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN 273
K +L++G +P++GLGT+ E+G+ ++ A+ AGYR IDTA LY N
Sbjct: 4 KVPIFTLSNGVLMPSIGLGTWQMTGEEGKTVIRN---------AVLAGYRHIDTATLYQN 54
Query: 274 EDQIGAAVR---ASGI-PREDIFIVTK-LPMDNQRDVVKQ-LEKSLARLNMSYVDLYLIH 435
E QIG A+ A GI REDIFI TK + DVV++ L SL RL + YVDLYL H
Sbjct: 55 EHQIGDALAELFAEGILKREDIFITTKAFCHEVAPDVVEEALRNSLKRLRLDYVDLYLAH 114
Query: 436 NPVAFNPGFKGFDIVDYLDTWKGMEEAKNLG 528
P + V D W+G E+ LG
Sbjct: 115 IPASTKDDGSFRSDVKVEDIWRGFEKVYGLG 145
>UniRef50_Q8EVT8 Cluster: Oxidoreductase-aldo/keto reductase family;
n=1; Mycoplasma penetrans|Rep: Oxidoreductase-aldo/keto
reductase family - Mycoplasma penetrans
Length = 299
Score = 82.6 bits (195), Expect = 6e-15
Identities = 45/113 (39%), Positives = 67/113 (59%), Gaps = 1/113 (0%)
Frame = +1
Query: 106 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 285
++LNDG IP +GLGT + + +K ALE G RL DTA+LY NE ++
Sbjct: 37 LTLNDGYQIPIIGLGT---------TSLHNQTCKNAIKAALEIGIRLFDTASLYGNEKEV 87
Query: 286 GAAVRASGIPREDIFIVTKL-PMDNQRDVVKQLEKSLARLNMSYVDLYLIHNP 441
G +R S I R +IF++TKL P + K +E++L +LN Y+D+ L+H+P
Sbjct: 88 GETIRESNINRNEIFVITKLYPGAQFANPEKAIEEALNKLNTDYIDMMLLHHP 140
>UniRef50_A0AWM8 Cluster: Aldo/keto reductase; n=4;
Actinomycetales|Rep: Aldo/keto reductase - Arthrobacter
sp. (strain FB24)
Length = 287
Score = 82.6 bits (195), Expect = 6e-15
Identities = 45/137 (32%), Positives = 81/137 (59%), Gaps = 2/137 (1%)
Frame = +1
Query: 103 KISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQ 282
++ L G++IP LGLGT+ ++ + E V++AL++GYRL+DTA Y NE+
Sbjct: 15 RLKLPHGHTIPRLGLGTWPMLED---------ECETAVRFALQSGYRLVDTAFQYRNEEA 65
Query: 283 IGAAVRASGIPREDIFIVTKLPMDNQR--DVVKQLEKSLARLNMSYVDLYLIHNPVAFNP 456
+G +R +G+PR ++FI +K ++ V + ++SL +L + ++D+++ H PV P
Sbjct: 66 VGRGIRTAGVPRSELFISSKFNKESHSIDGVQRAYDESLRKLGLDHLDMFMCHWPV---P 122
Query: 457 GFKGFDIVDYLDTWKGM 507
+ Y+D WKG+
Sbjct: 123 A-----LGKYVDAWKGL 134
>UniRef50_A7BES9 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 282
Score = 82.2 bits (194), Expect = 8e-15
Identities = 46/113 (40%), Positives = 71/113 (62%), Gaps = 1/113 (0%)
Frame = +1
Query: 106 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 285
I+LN+G +IP +GLGT+L ++P D++ V +AL+ Y LIDTA +Y+NE +
Sbjct: 4 ITLNNGITIPQVGLGTYL---------LEPDDAQSAVTYALDNDYTLIDTANVYVNERAV 54
Query: 286 GAAVRASGIPREDIFIVTKL-PMDNQRDVVKQLEKSLARLNMSYVDLYLIHNP 441
G +RAS R++IF+ TKL P +R +E++L RL Y+DL ++H P
Sbjct: 55 GRGMRASSKARDEIFLETKLWPSFFER--ASAVEETLERLGTDYIDLMILHQP 105
>UniRef50_Q6TY50 Cluster: Reductase 2; n=10; Magnoliophyta|Rep:
Reductase 2 - Hydrangea macrophylla (Bigleaf hydrangea)
Length = 321
Score = 82.2 bits (194), Expect = 8e-15
Identities = 57/150 (38%), Positives = 80/150 (53%), Gaps = 14/150 (9%)
Frame = +1
Query: 121 GNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGAAVR 300
G +P LGLGT V P K V AL+ GYR DTAALY +E +G A+
Sbjct: 14 GRKMPVLGLGT------AADPPVDPETVRKAVTEALKLGYRHFDTAALYNSEQPLGDAIA 67
Query: 301 AS---GI--PREDIFIVTKL-PMDNQRDVVKQ-LEKSLARLNMSYVDLYLIHNPVAFNPG 459
+ G+ R+++FI +KL D R+ V+ L+K+L L + Y+D+YLIH PV+ PG
Sbjct: 68 EALGEGLIKSRDELFITSKLWCSDAHRENVEPALQKTLKNLKLEYIDMYLIHWPVSSKPG 127
Query: 460 FKGFDI-------VDYLDTWKGMEEAKNLG 528
+ I +DY W+ MEE + LG
Sbjct: 128 NYEYPIKKEDFLQMDYKSVWEAMEECQKLG 157
>UniRef50_Q7QK25 Cluster: ENSANGP00000019775; n=2; Anopheles gambiae
str. PEST|Rep: ENSANGP00000019775 - Anopheles gambiae
str. PEST
Length = 319
Score = 82.2 bits (194), Expect = 8e-15
Identities = 59/161 (36%), Positives = 88/161 (54%), Gaps = 20/161 (12%)
Frame = +1
Query: 106 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 285
+ ++G IP LG GT+L +KGQ + VK A++ GYR IDTA LY NE +I
Sbjct: 8 VRFSNGYEIPVLGYGTYLA--QKGQ-------CVELVKKAIDLGYRHIDTAFLYENEVEI 58
Query: 286 GAAVR---ASG-IPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIHNPVA 447
G A+R A G I RED+F+ TKL + + V + +S L++ Y+DL+L+H+P+
Sbjct: 59 GQAIRDKIAEGVIRREDVFVTTKLWNTFHDPQHVEEAFRRSFDMLDIGYIDLFLMHSPMG 118
Query: 448 FN-PGFKGFDI-------------VDYLDTWKGMEEAKNLG 528
G++ D+ VDY++TWK ME+ G
Sbjct: 119 VQFSGYEYADMQPKDAAGNMLFSDVDYVETWKAMEKLVTAG 159
>UniRef50_UPI0000499B0E Cluster: oxidoreductase, aldo/keto reductase
family; n=1; Entamoeba histolytica HM-1:IMSS|Rep:
oxidoreductase, aldo/keto reductase family - Entamoeba
histolytica HM-1:IMSS
Length = 307
Score = 81.4 bits (192), Expect = 1e-14
Identities = 55/148 (37%), Positives = 77/148 (52%), Gaps = 9/148 (6%)
Frame = +1
Query: 112 LNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGA 291
LN+G +PA+GLGT+L PG+ K V ALE GYRLID A Y NE +IG
Sbjct: 8 LNNGKFMPAIGLGTWLA---------APGEVGKAVTLALENGYRLIDCARFYKNEKEIGE 58
Query: 292 AVRASGI---PREDIFIVTKLPMDNQRDVVKQLEKSLARLNMSYVDLYLIHNPVAFN--- 453
+ PRE++F+ +KL MD + + +S+ L Y+DLYLIH P+A
Sbjct: 59 MGIEPFLKNHPREELFVTSKLWMDQVTRIRESCLESIQDLKCKYLDLYLIHWPIALKVDA 118
Query: 454 ---PGFKGFDIVDYLDTWKGMEEAKNLG 528
P + F +D + W+ ME + G
Sbjct: 119 SNPPKPEDFLDMDITEIWQEMERLVDEG 146
>UniRef50_Q22352 Cluster: Putative uncharacterized protein T08H10.1;
n=2; Caenorhabditis|Rep: Putative uncharacterized
protein T08H10.1 - Caenorhabditis elegans
Length = 333
Score = 81.4 bits (192), Expect = 1e-14
Identities = 58/153 (37%), Positives = 82/153 (53%), Gaps = 17/153 (11%)
Frame = +1
Query: 106 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 285
I LN G +P GLGT+ DE + ++ AL+AGYRLIDTA LY NE I
Sbjct: 6 IPLNTGAQLPLFGLGTWQVKDE--------AELTVALRAALDAGYRLIDTAHLYQNEHII 57
Query: 286 GAAVR---ASG-IPREDIFIVTKLPMDNQ--RDVVKQLEKSLARLNMSYVDLYLIHNPV- 444
G + +SG + REDIF+ +KLP DV K +E L L + Y+DLYLIH P
Sbjct: 58 GKVLHEYISSGKLKREDIFVTSKLPFTAHAPEDVPKCVESQLKALQLEYIDLYLIHCPFP 117
Query: 445 ------AFNPGFKGFDI----VDYLDTWKGMEE 513
+F P + ++ + ++DTW+ +E+
Sbjct: 118 FKHQEGSFAPLMENGELAVTEIAHIDTWRALEK 150
>UniRef50_A7EW94 Cluster: Putative uncharacterized protein; n=1;
Sclerotinia sclerotiorum 1980|Rep: Putative
uncharacterized protein - Sclerotinia sclerotiorum 1980
Length = 326
Score = 81.4 bits (192), Expect = 1e-14
Identities = 52/145 (35%), Positives = 70/145 (48%), Gaps = 2/145 (1%)
Frame = +1
Query: 100 SKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNED 279
SK+ +N G IP LG G + + E V A +AGYR +D+AA Y NE
Sbjct: 44 SKLRMNSGYEIPILGYGVY---------QTPASQCEDLVAKAFDAGYRHVDSAAAYRNEG 94
Query: 280 QIGAAVRASGIPREDIFIVTKLPMD--NQRDVVKQLEKSLARLNMSYVDLYLIHNPVAFN 453
AA+R S IPREDIF +K+P + + Q+ K+L + Y+DL LIH P
Sbjct: 95 PCAAAIRRSSIPREDIFFTSKIPPRSLSYENTKAQVAKTLMETGLGYIDLMLIHAPYGGR 154
Query: 454 PGFKGFDIVDYLDTWKGMEEAKNLG 528
KG WK + EA+ G
Sbjct: 155 AARKG--------AWKALVEAQEEG 171
>UniRef50_Q28P63 Cluster: Aldo/keto reductase; n=4;
Rhodobacteraceae|Rep: Aldo/keto reductase - Jannaschia
sp. (strain CCS1)
Length = 276
Score = 81.0 bits (191), Expect = 2e-14
Identities = 50/144 (34%), Positives = 82/144 (56%), Gaps = 3/144 (2%)
Frame = +1
Query: 106 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 285
I +DG IP +G G + +V + + V+ A+E GYR+ID A LY+NE +
Sbjct: 7 IKFHDGAQIPQVGFGIW---------QVPQDIAGETVRSAIEIGYRMIDGAYLYMNEAGL 57
Query: 286 GAAVRASGIPREDIFIVTKLPMDNQRDVVK---QLEKSLARLNMSYVDLYLIHNPVAFNP 456
G +RASG+PR+++F+ TK+ +N++ K +E+SL + + +DL LIH PV
Sbjct: 58 GEGLRASGLPRDEVFVTTKV-WNNEQGAAKARASVERSLKTIGVEQLDLVLIHWPVPSQ- 115
Query: 457 GFKGFDIVDYLDTWKGMEEAKNLG 528
D+ YL+TWK ++ ++ G
Sbjct: 116 -----DL--YLETWKAFQDMRDEG 132
>UniRef50_Q55FL3 Cluster: Aldo-keto reductase; n=2; Dictyostelium
discoideum AX4|Rep: Aldo-keto reductase - Dictyostelium
discoideum AX4
Length = 321
Score = 81.0 bits (191), Expect = 2e-14
Identities = 52/123 (42%), Positives = 69/123 (56%), Gaps = 6/123 (4%)
Frame = +1
Query: 100 SKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNED 279
+ LNDGN IP++GLGT+ + E PG+ + AL+ GYR ID AA Y NE
Sbjct: 15 NNFKLNDGNQIPSIGLGTY--YSEN------PGEVGDAINNALKNGYRHIDGAAFYGNEK 66
Query: 280 QIGAAVRA----SGIPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIHNP 441
IG +++ I REDIF +KL N VVK K++ L + Y+DLYLIH P
Sbjct: 67 VIGNSLKEIFKEGEIKREDIFYTSKLWNSCHNSNLVVKHCVKTIEDLGIGYLDLYLIHWP 126
Query: 442 VAF 450
+AF
Sbjct: 127 IAF 129
>UniRef50_Q5XJM7 Cluster: Zgc:101765; n=5; Eumetazoa|Rep: Zgc:101765
- Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 288
Score = 80.6 bits (190), Expect = 2e-14
Identities = 51/117 (43%), Positives = 68/117 (58%), Gaps = 5/117 (4%)
Frame = +1
Query: 106 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 285
+ LN+ +P LGLGTF +GQ+ D+ V AL+AGYR DTAA+Y NE +
Sbjct: 8 VLLNNDIQMPLLGLGTFR---LQGQE-----DTYSAVDAALKAGYRAFDTAAVYRNEAHL 59
Query: 286 GAAVRA----SGIPREDIFIVTKL-PMDNQRDVVKQLEKSLARLNMSYVDLYLIHNP 441
G A+R G+ RED+FI +KL P D +KSL +L + Y+DLYLIH P
Sbjct: 60 GHALRCLLPKHGLSREDVFITSKLGPKDQGSKARNGCQKSLEQLGLGYIDLYLIHWP 116
>UniRef50_Q03PG5 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=1; Lactobacillus brevis ATCC
367|Rep: Aldo/keto reductase of diketogulonate reductase
family - Lactobacillus brevis (strain ATCC 367 / JCM
1170)
Length = 268
Score = 80.6 bits (190), Expect = 2e-14
Identities = 53/135 (39%), Positives = 78/135 (57%), Gaps = 2/135 (1%)
Frame = +1
Query: 112 LNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGA 291
L++G +IP LG GT+L D K D +K AL+AGYR +D A +Y NE +G
Sbjct: 6 LSNGVTIPMLGFGTYL-IDSK--------DVPAAIKTALDAGYRHLDCAHIYGNEPAVGE 56
Query: 292 AVRASGIPREDIFIVTKL-PMDNQRD-VVKQLEKSLARLNMSYVDLYLIHNPVAFNPGFK 465
A++ASGI R D+FI +K+ D D + +++L+ L + Y+DLYLIH P
Sbjct: 57 AIKASGIDRSDLFITSKVWNADQGYDKTLAAFDQTLSDLQLDYLDLYLIH-----WPNED 111
Query: 466 GFDIVDYLDTWKGME 510
F++ LDTW+ +E
Sbjct: 112 DFELT--LDTWRVLE 124
>UniRef50_Q6NII7 Cluster: Putative oxidoreductase; n=2;
Corynebacterium|Rep: Putative oxidoreductase -
Corynebacterium diphtheriae
Length = 290
Score = 80.2 bits (189), Expect = 3e-14
Identities = 45/118 (38%), Positives = 72/118 (61%), Gaps = 6/118 (5%)
Frame = +1
Query: 106 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 285
I+LNDG +PA+G GT+ +++ D+ + V+ A+E GYR IDTA+LY NE+++
Sbjct: 14 ITLNDGTEMPAIGFGTY---------KLREQDAYRAVRSAIEVGYRHIDTASLYKNEEEV 64
Query: 286 GAAV----RASGIPREDIFIVTKLPMDNQRDVVKQ--LEKSLARLNMSYVDLYLIHNP 441
G AV A + R+++FI TK+ D D + Q ++SL RL + Y+D ++H P
Sbjct: 65 GRAVADAITAGEVARDELFITTKVWNDMHGDQLTQRSFQESLHRLGLDYIDCCMVHWP 122
>UniRef50_Q5FK99 Cluster: Oxidoreductase aldo-keto reductase family;
n=5; Lactobacillus|Rep: Oxidoreductase aldo-keto
reductase family - Lactobacillus acidophilus
Length = 289
Score = 80.2 bits (189), Expect = 3e-14
Identities = 49/144 (34%), Positives = 72/144 (50%), Gaps = 2/144 (1%)
Frame = +1
Query: 103 KISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQ 282
KI LNDGN IP LG G F + ++ K V+ A+ GYRLIDTA Y N+
Sbjct: 6 KIKLNDGNEIPQLGFGVF--------QISNHDEAVKAVESAISNGYRLIDTAEAYNNQTA 57
Query: 283 IGAAVRASGIPREDIFIVTKLPMDN--QRDVVKQLEKSLARLNMSYVDLYLIHNPVAFNP 456
+G A++ S + R+DIF+ TKL + N K +++ L L Y+D+ L+H
Sbjct: 58 VGEAIKNSDVNRDDIFLTTKLWVSNFTYEKASKAIDEDLKELGTDYIDMMLLHQAYG--- 114
Query: 457 GFKGFDIVDYLDTWKGMEEAKNLG 528
D W+ +E+A+ G
Sbjct: 115 --------DVAGAWRALEDAQKAG 130
>UniRef50_Q7ZA52 Cluster: Aldose reductase; n=6; Pezizomycotina|Rep:
Aldose reductase - Magnaporthe grisea (Rice blast
fungus) (Pyricularia grisea)
Length = 312
Score = 80.2 bits (189), Expect = 3e-14
Identities = 60/157 (38%), Positives = 88/157 (56%), Gaps = 17/157 (10%)
Frame = +1
Query: 109 SLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIG 288
+LN G IPA GLGT+ G +KG ++ V A+++GYRLID A +Y NE+++G
Sbjct: 7 TLNTGAKIPAFGLGTWQG--DKGV-------IKEAVLTAIKSGYRLIDGAYVYGNEEEVG 57
Query: 289 AAVR---ASGI-PREDIFIVTKLPMDNQRDVVKQLEKSLARLNMSYVDLYLIHNPVAFNP 456
+R +SGI RED+F+V+K L++SL L + YVDLYL+H P+ NP
Sbjct: 58 QGIREAISSGIVKREDLFVVSKCWATYTTRCELGLDQSLKLLGLDYVDLYLVHWPILMNP 117
Query: 457 --GFKGF--------DIV---DYLDTWKGMEEAKNLG 528
+ F DI+ +++DTWK ME+ G
Sbjct: 118 EGNDEKFPKHADGSRDIIHTHNHVDTWKLMEKLPATG 154
>UniRef50_UPI00015B40FA Cluster: PREDICTED: similar to CG2767-PA;
n=2; Nasonia vitripennis|Rep: PREDICTED: similar to
CG2767-PA - Nasonia vitripennis
Length = 356
Score = 79.8 bits (188), Expect = 4e-14
Identities = 51/120 (42%), Positives = 68/120 (56%), Gaps = 5/120 (4%)
Frame = +1
Query: 106 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 285
I L+ G+ +P +GLGT+ ++ P E V ALE+GYR IDTA Y NE+ I
Sbjct: 28 IKLSSGHDMPMIGLGTW---------QMPPEAIEVAVTAALESGYRHIDTAFTYGNEEAI 78
Query: 286 GAAVRA---SGIPREDIFIVTKLPMDNQRD--VVKQLEKSLARLNMSYVDLYLIHNPVAF 450
G ++ G RED+FI TKLP R V L+ SL +L + YV++YLIH P AF
Sbjct: 79 GKTLKKWFDKGGKREDLFITTKLPPIGMRAEYVESYLKLSLEKLGLEYVNMYLIHKPFAF 138
>UniRef50_A0JRJ3 Cluster: 2,5-didehydrogluconate reductase; n=3;
Actinobacteria (class)|Rep: 2,5-didehydrogluconate
reductase - Arthrobacter sp. (strain FB24)
Length = 276
Score = 79.8 bits (188), Expect = 4e-14
Identities = 54/137 (39%), Positives = 71/137 (51%), Gaps = 2/137 (1%)
Frame = +1
Query: 106 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 285
I LNDG+ IP +GLGT+ D + V A+E GYR IDTA Y NE +
Sbjct: 7 IELNDGHRIPQIGLGTWPLDDHQVAAAVVN---------AVEGGYRHIDTAVKYGNEKGV 57
Query: 286 GAAVRASGIPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIHNPVAFNPG 459
G +R+SG+ R ++FI TKL Q V L+ SL RL + YVDL LIH P+
Sbjct: 58 GNGIRSSGLDRSELFITTKLDGEFQGQDRAVAGLDGSLKRLGLDYVDLLLIHWPLPRRD- 116
Query: 460 FKGFDIVDYLDTWKGME 510
+++ TWK E
Sbjct: 117 -------EFISTWKTFE 126
>UniRef50_Q235V6 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=2; Tetrahymena thermophila SB210|Rep:
Oxidoreductase, aldo/keto reductase family protein -
Tetrahymena thermophila SB210
Length = 332
Score = 79.8 bits (188), Expect = 4e-14
Identities = 52/148 (35%), Positives = 80/148 (54%), Gaps = 4/148 (2%)
Frame = +1
Query: 97 ASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNE 276
A LN+G +P +GLGT+L KE + ++ AL+AGYR IDTA Y NE
Sbjct: 5 AHSSKLNNGQIMPLVGLGTYL----LNSKE----EMTNLLRTALDAGYRHIDTAVNYQNE 56
Query: 277 DQIGAAVRA----SGIPREDIFIVTKLPMDNQRDVVKQLEKSLARLNMSYVDLYLIHNPV 444
IG +++ R+D+FIV+K+ + ++++ ++KSL L + YVDLY +H P+
Sbjct: 57 AMIGESLKTIFKEGKYSRKDLFIVSKVFPNKGINMLESVKKSLKELQLDYVDLYYLHFPL 116
Query: 445 AFNPGFKGFDIVDYLDTWKGMEEAKNLG 528
F + F + W +EEA LG
Sbjct: 117 GFLSEKEEFVHLPVHVAWAQLEEAHRLG 144
>UniRef50_Q4JX70 Cluster: Putative oxidoreductase; n=1;
Corynebacterium jeikeium K411|Rep: Putative
oxidoreductase - Corynebacterium jeikeium (strain K411)
Length = 285
Score = 79.4 bits (187), Expect = 6e-14
Identities = 48/116 (41%), Positives = 67/116 (57%), Gaps = 4/116 (3%)
Frame = +1
Query: 106 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 285
+ +NDG + P LGLG + DE D+ V+ A+E GYR IDTAA+Y NE+ +
Sbjct: 11 LEMNDGKTTPQLGLGVWQLSDE---------DTYTSVRAAIETGYRHIDTAAIYGNEEAV 61
Query: 286 GAAV----RASGIPREDIFIVTKLPMDNQRDVVKQLEKSLARLNMSYVDLYLIHNP 441
G AV +A + RE++FI TKL +Q + +S +L M YVDLYL+H P
Sbjct: 62 GRAVADAVKAGDVQREELFITTKLWNADQACGKEAFAESQKKLGMDYVDLYLLHWP 117
>UniRef50_Q01HB5 Cluster: OSIGBa0136O08-OSIGBa0153H12.9 protein;
n=4; Oryza sativa|Rep: OSIGBa0136O08-OSIGBa0153H12.9
protein - Oryza sativa (Rice)
Length = 337
Score = 79.4 bits (187), Expect = 6e-14
Identities = 57/159 (35%), Positives = 80/159 (50%), Gaps = 18/159 (11%)
Frame = +1
Query: 106 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 285
++LN G+++P LG GT P D + A+ GYR +DTAA+Y E +
Sbjct: 23 VTLNSGHAMPVLGFGT--------GSSTPPADLAATIAHAVRLGYRHLDTAAVYGTEGAV 74
Query: 286 GAAV----RASGIP-REDIFIVTKLPMDNQRD--VVKQLEKSLARLNMSYVDLYLIHNPV 444
GAAV R + R ++F+ TKL M + VV L +SL+RL + YVDL+LIH PV
Sbjct: 75 GAAVAEAVRCGAVASRGELFVTTKLSMADAHPPRVVAALRESLSRLGLDYVDLFLIHWPV 134
Query: 445 A-----------FNPGFKGFDIVDYLDTWKGMEEAKNLG 528
A ++ +G D W+GMEE LG
Sbjct: 135 AIGKKDAAGELTWDDLSRGLVPFDMEGVWRGMEECHRLG 173
>UniRef50_Q7PCV3 Cluster: ENSANGP00000031808; n=9;
Endopterygota|Rep: ENSANGP00000031808 - Anopheles
gambiae str. PEST
Length = 316
Score = 79.4 bits (187), Expect = 6e-14
Identities = 58/154 (37%), Positives = 82/154 (53%), Gaps = 17/154 (11%)
Frame = +1
Query: 118 DGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIG--- 288
+GNSIP GLGT+ PG + VK A++ GYR ID A +Y NE ++G
Sbjct: 13 NGNSIPMFGLGTW---------NSPPGQVAQAVKDAIDVGYRHIDCAHVYQNEHEVGEGI 63
Query: 289 AAVRASG-IPREDIFIVTKLPMDNQR-DVVK-QLEKSLARLNMSYVDLYLIHNPVAFNPG 459
AA A G + RED+F+ +KL R D+V+ + +L L + Y+DLYLIH PV + G
Sbjct: 64 AAKIAEGVVKREDLFVTSKLWNTFHRPDLVEGACKTTLQNLKLDYLDLYLIHWPVGYQEG 123
Query: 460 FKGFDI-----------VDYLDTWKGMEEAKNLG 528
+ F + DY+DTW ME+ + G
Sbjct: 124 TELFPMGPDGKTFLFSDADYVDTWPEMEKLVDAG 157
>UniRef50_A7SIT3 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 323
Score = 79.4 bits (187), Expect = 6e-14
Identities = 52/124 (41%), Positives = 75/124 (60%), Gaps = 6/124 (4%)
Frame = +1
Query: 112 LNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGA 291
LN G SIPA+ LGT+ + ++EV G++ V+ A+E GYR ID A +Y NE +IG
Sbjct: 10 LNTGASIPAMALGTW----QSSKEEV--GNA---VRLAIELGYRHIDCAEIYGNEGEIGE 60
Query: 292 A---VRASG-IPREDIFIVTKLPMDNQR--DVVKQLEKSLARLNMSYVDLYLIHNPVAFN 453
A V G + RE++F+ +KL D+ DV+ + +L L + Y+DLYLIH PVAF
Sbjct: 61 ALSEVLTEGKVKREELFVTSKLWCDSHHPDDVLPACQATLKNLQLDYLDLYLIHIPVAFK 120
Query: 454 PGFK 465
G +
Sbjct: 121 KGVR 124
>UniRef50_UPI0000519CC2 Cluster: PREDICTED: similar to CG2767-PA;
n=1; Apis mellifera|Rep: PREDICTED: similar to CG2767-PA
- Apis mellifera
Length = 321
Score = 79.0 bits (186), Expect = 8e-14
Identities = 52/121 (42%), Positives = 69/121 (57%), Gaps = 6/121 (4%)
Frame = +1
Query: 106 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 285
I L +G +P +G GT+ + +KE+ E + ALEAGYR IDTA Y NE I
Sbjct: 6 ILLPNGELMPIIGFGTW----QAQEKEL-----EDALNIALEAGYRHIDTATSYENEKVI 56
Query: 286 GAAVR----ASGIPREDIFIVTKLPMDNQR--DVVKQLEKSLARLNMSYVDLYLIHNPVA 447
G ++ + + R DIFIVTKLP R DV K ++ SL L + Y+DLYLIH P+
Sbjct: 57 GDVLKNWFDSKKLKRSDIFIVTKLPAVGNRAEDVEKWIKTSLQNLRLEYLDLYLIHVPIG 116
Query: 448 F 450
F
Sbjct: 117 F 117
>UniRef50_Q568D7 Cluster: Zgc:110366; n=7; Euteleostomi|Rep:
Zgc:110366 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 289
Score = 79.0 bits (186), Expect = 8e-14
Identities = 57/144 (39%), Positives = 80/144 (55%), Gaps = 3/144 (2%)
Frame = +1
Query: 106 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWAL-EAGYRLIDTAALYLNEDQ 282
+ L++G +IP LGLGT G G S + V +AL E G R IDTA Y E+
Sbjct: 16 VPLHNGLNIPILGLGT----SHYG------GYSHEAVLYALQECGIRHIDTAKRYGCEEA 65
Query: 283 IGAAVRASGIPREDIFIVTKL-PMDNQRDVVKQ-LEKSLARLNMSYVDLYLIHNPVAFNP 456
+G AV SG+ RE++++ TKL P D KQ S ARL + Y+DLYL+H P + P
Sbjct: 66 LGKAVTESGVQREELWVTTKLWPGDYGYQSTKQACRDSRARLGVDYLDLYLMHWPDSMVP 125
Query: 457 GFKGFDIVDYLDTWKGMEEAKNLG 528
G ++ L+TW+ +EE + G
Sbjct: 126 GRSSQEV--RLETWRALEELYDEG 147
>UniRef50_A6ESC0 Cluster: ARA1; n=1; unidentified eubacterium
SCB49|Rep: ARA1 - unidentified eubacterium SCB49
Length = 280
Score = 79.0 bits (186), Expect = 8e-14
Identities = 46/136 (33%), Positives = 80/136 (58%), Gaps = 2/136 (1%)
Frame = +1
Query: 112 LNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGA 291
LN+ +IPA+G GT+ D GQ + +K A++AGY+ ID AA+Y NE +G
Sbjct: 7 LNNNINIPAIGFGTWQTPD--GQTAINA------IKTAIDAGYKHIDAAAIYKNEKGVGL 58
Query: 292 AVRASGIPREDIFIVTKLPMDNQ--RDVVKQLEKSLARLNMSYVDLYLIHNPVAFNPGFK 465
++ + I R+D+F+ +K+ + + + +K + ++ L + Y+DLYLIH P A + F+
Sbjct: 59 GIKEANIDRKDLFVTSKVWNEQRGYENTLKAFDNTINDLQLDYLDLYLIHWPAAAHQ-FE 117
Query: 466 GFDIVDYLDTWKGMEE 513
+ ++ DTW ME+
Sbjct: 118 NWKQLNN-DTWSAMEK 132
>UniRef50_Q5HR31 Cluster: Oxidoreductase, aldo/keto reductase
family; n=3; Staphylococcus|Rep: Oxidoreductase,
aldo/keto reductase family - Staphylococcus epidermidis
(strain ATCC 35984 / RP62A)
Length = 279
Score = 78.6 bits (185), Expect = 1e-13
Identities = 45/112 (40%), Positives = 67/112 (59%), Gaps = 2/112 (1%)
Frame = +1
Query: 112 LNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGA 291
LN+G +PA+GLG + DE+ E+ V+ AL+AGYR DTA Y NE +G+
Sbjct: 8 LNNGYPMPAVGLGVYKIADEQ---------MEEVVRTALDAGYRAFDTAYFYGNEKALGS 58
Query: 292 AVRASGIPREDIFIVTKLPMDNQ--RDVVKQLEKSLARLNMSYVDLYLIHNP 441
A++ S + R+++FI +KL D Q ++ KSL L + Y+DL+LIH P
Sbjct: 59 ALKHSNVERDELFITSKLWNDYQGYDQTIEYFNKSLDNLGLDYLDLFLIHWP 110
>UniRef50_Q5K8C5 Cluster: Aldo-keto reductase, putative; n=1;
Filobasidiella neoformans|Rep: Aldo-keto reductase,
putative - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 303
Score = 78.6 bits (185), Expect = 1e-13
Identities = 45/120 (37%), Positives = 69/120 (57%), Gaps = 5/120 (4%)
Frame = +1
Query: 100 SKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNED 279
+++ ++DGN+IP GLG + E+ ++ VKWALEAGYR +DTA Y NE
Sbjct: 31 ARLKMHDGNAIPQFGLGVY---------EMNDKETYDCVKWALEAGYRHVDTAEWYENEA 81
Query: 280 QIGAAV----RASGIPREDIFIVTKLPMDNQ-RDVVKQLEKSLARLNMSYVDLYLIHNPV 444
G A+ +A+G RE+IF+ +KL ++ L+ SL R + Y DLYL+H+ +
Sbjct: 82 PCGKAIADFLKATGTSREEIFLTSKLKNNSSYEQAFVDLKGSLKRSGVEYFDLYLMHSAI 141
>UniRef50_UPI0000E4A7CE Cluster: PREDICTED: similar to LOC553452
protein; n=6; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to LOC553452 protein -
Strongylocentrotus purpuratus
Length = 321
Score = 78.2 bits (184), Expect = 1e-13
Identities = 53/158 (33%), Positives = 83/158 (52%), Gaps = 17/158 (10%)
Frame = +1
Query: 106 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 285
I L G +P LG GT+ ++KP + + ++ A++ GYR ID A+LY NE +
Sbjct: 8 IVLPGGRKLPLLGFGTW---------QIKPEEVGRVIETAIDCGYRHIDEASLYGNEKGV 58
Query: 286 GAAVRA----SGIPREDIFIVTKLPMDNQRD--VVKQLEKSLARLNMSYVDLYLIHNPVA 447
G ++A I RED+F+ +KL + + V +SL+ L ++Y+DL+LIH P +
Sbjct: 59 GDGIKAKIDDGTIKREDLFVTSKLWVTDSHPSRVEPSCRQSLSDLGLAYLDLFLIHCPTS 118
Query: 448 FNPG-----------FKGFDIVDYLDTWKGMEEAKNLG 528
G F G D +DY+DTW+ ME + G
Sbjct: 119 AVGGKGPFPMDDNGLFIGDDTIDYVDTWRIMESLVDKG 156
>UniRef50_Q9A2X8 Cluster: Oxidoreductase, aldo/keto reductase
family; n=3; Caulobacter|Rep: Oxidoreductase, aldo/keto
reductase family - Caulobacter crescentus (Caulobacter
vibrioides)
Length = 279
Score = 78.2 bits (184), Expect = 1e-13
Identities = 45/106 (42%), Positives = 66/106 (62%), Gaps = 2/106 (1%)
Frame = +1
Query: 130 IPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGAAVRASG 309
+PALG GT+ +++ G + V+ ALE GYR IDTA +Y NE +GAA+R SG
Sbjct: 15 MPALGFGTW---------QLENGTAVPLVEKALEIGYRHIDTAQIYGNERDVGAAIRNSG 65
Query: 310 IPREDIFIVTKLPMDN--QRDVVKQLEKSLARLNMSYVDLYLIHNP 441
+ R++IF+ TK+ +D D+ + EKSL +L + VDL L+H P
Sbjct: 66 VKRDEIFLTTKVWIDQFADGDLQRSAEKSLEKLGVDQVDLLLLHWP 111
>UniRef50_Q0SFM4 Cluster: Probable 2,5-didehydrogluconate reductase;
n=1; Rhodococcus sp. RHA1|Rep: Probable
2,5-didehydrogluconate reductase - Rhodococcus sp.
(strain RHA1)
Length = 265
Score = 78.2 bits (184), Expect = 1e-13
Identities = 44/107 (41%), Positives = 64/107 (59%), Gaps = 2/107 (1%)
Frame = +1
Query: 130 IPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGAAVRASG 309
IP LGLGT+ + D+ + V +EAGYRLIDTA +Y NED +G A+ G
Sbjct: 4 IPPLGLGTW---------PLTGPDATRAVLSGIEAGYRLIDTATIYDNEDAVGVALAECG 54
Query: 310 IPREDIFIVTKLPMDN--QRDVVKQLEKSLARLNMSYVDLYLIHNPV 444
+PRE++F+ TKL + D+ +E+SL L + +DL+LIH P+
Sbjct: 55 VPREELFVTTKLRGSDHVSGDIRGAVERSLKNLGLDRLDLFLIHWPL 101
>UniRef50_Q4DJ59 Cluster: Aldo/keto reductase, putative; n=2;
Trypanosoma|Rep: Aldo/keto reductase, putative -
Trypanosoma cruzi
Length = 322
Score = 78.2 bits (184), Expect = 1e-13
Identities = 45/122 (36%), Positives = 70/122 (57%), Gaps = 3/122 (2%)
Frame = +1
Query: 85 GGGKASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAAL 264
GGG + + G IP +G+GT+ E+ +S V AL G+RL+DTAA
Sbjct: 11 GGGALPLLESSGGMRIPHMGVGTY---------ELYGDESRIAVLAALRLGFRLVDTAAG 61
Query: 265 YLNEDQIGAAVRASGIPREDIFIVTKL---PMDNQRDVVKQLEKSLARLNMSYVDLYLIH 435
Y NE+ +GAA+ SG+ RE++F+V K+ M ++ V K + +S+ +L ++Y D LIH
Sbjct: 62 YHNEEHVGAAIEESGVQREELFVVVKIAPKAMASEELVEKGIRESVRKLRIAYADCVLIH 121
Query: 436 NP 441
P
Sbjct: 122 WP 123
>UniRef50_Q0CLQ2 Cluster: Putative uncharacterized protein; n=1;
Aspergillus terreus NIH2624|Rep: Putative
uncharacterized protein - Aspergillus terreus (strain
NIH 2624)
Length = 301
Score = 78.2 bits (184), Expect = 1e-13
Identities = 46/109 (42%), Positives = 66/109 (60%), Gaps = 2/109 (1%)
Frame = +1
Query: 112 LNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGA 291
L+ G +PA+GLGT+L KP + E V+ AL GYR ID AA YLNE+++G
Sbjct: 9 LSSGYDMPAVGLGTWLS---------KPHEVENAVETALRLGYRHIDAAACYLNENEVGN 59
Query: 292 AVRASGIPREDIFIVTKL-PMDNQRDVVKQ-LEKSLARLNMSYVDLYLI 432
+ SG+PR+ IFI +KL + D V++ + K+L L Y+DLYL+
Sbjct: 60 GWKKSGVPRDQIFITSKLWNTHHHPDHVEEAVNKTLKDLQTDYLDLYLV 108
>UniRef50_A6RMS0 Cluster: Putative uncharacterized protein; n=1;
Botryotinia fuckeliana B05.10|Rep: Putative
uncharacterized protein - Botryotinia fuckeliana B05.10
Length = 286
Score = 78.2 bits (184), Expect = 1e-13
Identities = 55/142 (38%), Positives = 79/142 (55%), Gaps = 3/142 (2%)
Frame = +1
Query: 112 LNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGA 291
L +G+++PA+GLGTF G D G ++VK VK A++AGYR ID AA Y NE+ IG
Sbjct: 10 LVNGSTLPAIGLGTFQGDD--GNEKVK-----NIVKAAIQAGYRHIDGAAAYGNEEAIGD 62
Query: 292 AVRASGIPREDIFIVTKLPMDNQRDVVKQLEKSLARLNMSYVDLYLIHNPVAFNPGFKGF 471
A++ SGI R+++ P +DV + L+ SL L + YV P A+ PG
Sbjct: 63 AIKESGISRDEL----AQPWHEPKDVERALDLSLEALGLEYV-------PHAYLPGPNNV 111
Query: 472 DIV---DYLDTWKGMEEAKNLG 528
D Y +TW+ ME+ + G
Sbjct: 112 DYERSRKYTETWQAMEKLVDSG 133
>UniRef50_UPI0000588153 Cluster: PREDICTED: hypothetical protein;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 333
Score = 77.8 bits (183), Expect = 2e-13
Identities = 52/159 (32%), Positives = 84/159 (52%), Gaps = 18/159 (11%)
Frame = +1
Query: 106 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 285
++L G+++P +GLGT+ ++K + + A++AGYR D A +Y NE ++
Sbjct: 5 VTLPSGHAMPLVGLGTW---------KLKADEVAGAIGAAVDAGYRHFDCALIYGNEKEV 55
Query: 286 GAAVRAS----GIPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIHNPVA 447
G A+R + G+ RED+FI TK+ + DV + +SL L + Y+DLY++H P+
Sbjct: 56 GVALREAMQRLGLKREDVFITTKVWNTFHAKEDVAECFNRSLTDLQLDYIDLYIMHWPLG 115
Query: 448 FN--------PGFKGFDI----VDYLDTWKGMEEAKNLG 528
F P + DI V YL+TW ME+ G
Sbjct: 116 FQNLGPTVMFPRTETGDIVYSDVHYLETWSAMEDLVKTG 154
>UniRef50_Q89JN4 Cluster: Oxidoreductase; n=8; Rhizobiales|Rep:
Oxidoreductase - Bradyrhizobium japonicum
Length = 272
Score = 77.8 bits (183), Expect = 2e-13
Identities = 46/115 (40%), Positives = 70/115 (60%), Gaps = 2/115 (1%)
Frame = +1
Query: 118 DGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGAAV 297
+G IPA+GLGT+ E+ + V+ AL GYR IDTA +Y NE ++G V
Sbjct: 7 NGARIPAIGLGTW---------ELSGRPCARVVEQALRLGYRHIDTAQVYDNEREVGDGV 57
Query: 298 RASGIPREDIFIVTKLPMDN--QRDVVKQLEKSLARLNMSYVDLYLIHNPVAFNP 456
RASG+ R+D+F+ TK+ ++ D+ + +++SLARL + VDL L+H P + P
Sbjct: 58 RASGVRRDDVFLTTKVWTNHFAPNDLERSVKESLARLRLPSVDLLLLHWPNSHVP 112
>UniRef50_Q1IN88 Cluster: Aldehyde reductase; n=5; Bacteria|Rep:
Aldehyde reductase - Acidobacteria bacterium (strain
Ellin345)
Length = 313
Score = 77.8 bits (183), Expect = 2e-13
Identities = 53/127 (41%), Positives = 67/127 (52%), Gaps = 7/127 (5%)
Frame = +1
Query: 100 SKISLNDG-NSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNE 276
++I L+ G IPALG GT + P + + AL AG+R D A Y NE
Sbjct: 9 TRIPLHHGAGHIPALGFGTLIA---------DPALTITATRDALAAGFRHFDCAERYRNE 59
Query: 277 DQIGAAVRAS----GIPREDIFIVTKLPMDNQRD--VVKQLEKSLARLNMSYVDLYLIHN 438
++G A+RA I RE+IF+ TKL N R V E SL RL + Y+DLYLIH
Sbjct: 60 REVGEALRAGRAAGNIAREEIFVTTKLWNTNHRPERVEPAFEASLDRLGLDYLDLYLIHT 119
Query: 439 PVAFNPG 459
P AF PG
Sbjct: 120 PFAFQPG 126
>UniRef50_A3VHZ9 Cluster: Oxidoreductase; n=1; Rhodobacterales
bacterium HTCC2654|Rep: Oxidoreductase - Rhodobacterales
bacterium HTCC2654
Length = 278
Score = 77.8 bits (183), Expect = 2e-13
Identities = 45/117 (38%), Positives = 69/117 (58%), Gaps = 2/117 (1%)
Frame = +1
Query: 97 ASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNE 276
A ++L +G +P LGLGT+ D+ ++ K V A+E GYRLIDTA Y NE
Sbjct: 7 APTVTLANGVEMPQLGLGTWPMTDD---------EAAKAVATAIETGYRLIDTAENYKNE 57
Query: 277 DQIGAAVRASGIPREDIFIVTKLPMD-NQRDVVKQ-LEKSLARLNMSYVDLYLIHNP 441
+G +R +G+ R+++F+ TK+ + D ++ E SL RL + Y+DL+LIH P
Sbjct: 58 TGVGQGIRDAGVARDEVFLTTKMNKQWHSVDGARRACEASLERLGLDYIDLFLIHWP 114
>UniRef50_A3JU52 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=1; Rhodobacterales bacterium HTCC2150|Rep:
2,5-diketo-D-gluconic acid reductase A - Rhodobacterales
bacterium HTCC2150
Length = 334
Score = 77.8 bits (183), Expect = 2e-13
Identities = 48/128 (37%), Positives = 72/128 (56%), Gaps = 13/128 (10%)
Frame = +1
Query: 97 ASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNE 276
A+ +LN +IPA+G GT+L + D++ + A++AGYR IDTA+ Y NE
Sbjct: 37 ATTFTLNTTTTIPAVGFGTYL---------ISNDDAKSTISAAIQAGYRHIDTASGYQNE 87
Query: 277 DQIGAAVRA----SGIPREDIFIVTKLPMDN---------QRDVVKQLEKSLARLNMSYV 417
+GA ++A +GI R+D+F+ KL N + + + + SLARL + YV
Sbjct: 88 KTVGAGIKAGLQSAGITRKDLFVTAKLWPGNPAWGDAPKTKAQTLDECDASLARLGLDYV 147
Query: 418 DLYLIHNP 441
DLYLIH P
Sbjct: 148 DLYLIHAP 155
>UniRef50_Q838E0 Cluster: Oxidoreductase, aldo/keto reductase
family; n=24; Bacilli|Rep: Oxidoreductase, aldo/keto
reductase family - Enterococcus faecalis (Streptococcus
faecalis)
Length = 279
Score = 77.4 bits (182), Expect = 2e-13
Identities = 47/121 (38%), Positives = 69/121 (57%), Gaps = 6/121 (4%)
Frame = +1
Query: 97 ASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNE 276
A ++LN+G IP +GLG F DE+ K V+ G + GYRLIDTA +Y NE
Sbjct: 6 ADTVTLNNGTKIPGMGLGVFQIPDEETAKVVEEG---------IINGYRLIDTAQIYGNE 56
Query: 277 DQIGAAVR----ASGIPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIHN 438
GA ++ A+G+ RED+F+ +K+ + + ++ SL RL + Y+DLYLIH
Sbjct: 57 SGTGAGIKAGLAATGLNREDLFVTSKVWNAHISYDETIQAFNDSLERLGLDYLDLYLIHW 116
Query: 439 P 441
P
Sbjct: 117 P 117
>UniRef50_Q4V008 Cluster: Oxidoreductase; n=4; Proteobacteria|Rep:
Oxidoreductase - Xanthomonas campestris pv. campestris
(strain 8004)
Length = 267
Score = 77.4 bits (182), Expect = 2e-13
Identities = 48/107 (44%), Positives = 67/107 (62%), Gaps = 2/107 (1%)
Frame = +1
Query: 127 SIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGAAVRAS 306
++PA GLGTF K Q + DS V+ AL GYR IDTA +Y NE Q+G A+ +
Sbjct: 2 TVPAFGLGTFR---LKDQVVI---DS---VRNALALGYRAIDTAQIYDNEAQVGQAIADA 52
Query: 307 GIPREDIFIVTKLPMDN-QRDVVK-QLEKSLARLNMSYVDLYLIHNP 441
G+PR+ +F+ TK+ +D RD ++ L++SL +L YVDL LIH P
Sbjct: 53 GVPRDQLFVTTKIWVDRFSRDTLQPSLQESLRKLGTDYVDLTLIHWP 99
>UniRef50_Q17DN0 Cluster: Aldo-keto reductase; n=5; Culicidae|Rep:
Aldo-keto reductase - Aedes aegypti (Yellowfever
mosquito)
Length = 324
Score = 77.4 bits (182), Expect = 2e-13
Identities = 58/163 (35%), Positives = 80/163 (49%), Gaps = 22/163 (13%)
Frame = +1
Query: 106 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 285
+ LN+G +PA+GLGT + K + K V A++ G+R IDTA Y NED +
Sbjct: 9 VKLNNGLEMPAIGLGTSMS---------KGDECCKAVMTAIDEGFRHIDTAYNYRNEDVV 59
Query: 286 GAAVRA----SGIPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIHNPVA 447
G A+RA + RE++F+ TKL + V KSL L + YVDL+LIH P
Sbjct: 60 GRAIRAKIEEGVVTREELFVTTKLWNTFHHPDHVPMAFGKSLEHLGLDYVDLFLIHMPFG 119
Query: 448 FNPGFKGFDIV----------------DYLDTWKGMEEAKNLG 528
+ F G+D DY+DTWK ME+ G
Sbjct: 120 YE--FNGWDPEKRTPLDDNGNVLCSDDDYVDTWKAMEKLLESG 160
>UniRef50_Q929C8 Cluster: Lin2349 protein; n=12; Listeria|Rep:
Lin2349 protein - Listeria innocua
Length = 294
Score = 77.0 bits (181), Expect = 3e-13
Identities = 51/138 (36%), Positives = 76/138 (55%), Gaps = 2/138 (1%)
Frame = +1
Query: 103 KISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQ 282
++ L +IP +GLG F + ++E G EK A+E GYRL DTAA+Y NE
Sbjct: 8 RMILPGNETIPYIGLGVF----QVTEQEFIAGAVEK----AIEVGYRLFDTAAVYNNEAI 59
Query: 283 IGAAVRASGIPREDIFIVTKLPMDN--QRDVVKQLEKSLARLNMSYVDLYLIHNPVAFNP 456
+G A+ S +PRE++FI +K+ + + + E++L L + Y+DLYLIH PVA
Sbjct: 60 VGQAILDSAVPREELFISSKVWNGDLGYDETLFAFERTLRNLKLDYLDLYLIHWPVAGK- 118
Query: 457 GFKGFDIVDYLDTWKGME 510
Y D+W+ ME
Sbjct: 119 ---------YRDSWRAME 127
>UniRef50_A4FEB9 Cluster: 2,5-diketo-D-gluconic acid reductase; n=1;
Saccharopolyspora erythraea NRRL 2338|Rep:
2,5-diketo-D-gluconic acid reductase - Saccharopolyspora
erythraea (strain NRRL 23338)
Length = 159
Score = 77.0 bits (181), Expect = 3e-13
Identities = 45/114 (39%), Positives = 67/114 (58%), Gaps = 2/114 (1%)
Frame = +1
Query: 106 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 285
++LN+G +P LG G F +V ++ V ALEAGYR IDTAA Y NE +
Sbjct: 7 VTLNNGVEMPQLGYGVF---------QVPEDETAAAVGAALEAGYRSIDTAAAYGNEAAV 57
Query: 286 GAAVRASGIPREDIFIVTKLPMDNQ--RDVVKQLEKSLARLNMSYVDLYLIHNP 441
G A+ SG+ R+++F+ TKL +Q + ++ + SL L + ++DLYLIH P
Sbjct: 58 GRALAGSGLARDELFVTTKLWNADQGYDNALRAFDTSLELLGLDHLDLYLIHWP 111
>UniRef50_A7RUA2 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 246
Score = 77.0 bits (181), Expect = 3e-13
Identities = 48/113 (42%), Positives = 63/113 (55%), Gaps = 3/113 (2%)
Frame = +1
Query: 199 DSEKPVKWALEAGYRLIDTAALY-LNEDQIGAAVRASGIPREDIFIVTKLPMD--NQRDV 369
D+ VK ALE GYRLIDTA Y L+E Q+ A+ SGIPR+DIFI+TKL
Sbjct: 14 DTLSVVKTALETGYRLIDTAQGYPLSEPQVAKAIADSGIPRKDIFIITKLHPRYLGYEPT 73
Query: 370 VKQLEKSLARLNMSYVDLYLIHNPVAFNPGFKGFDIVDYLDTWKGMEEAKNLG 528
+K +E SL L+ Y+DL+LIH+ + ++WK MEE G
Sbjct: 74 LKSVEMSLRALSTDYIDLFLIHSKTG-----------TWKESWKAMEELHRQG 115
>UniRef50_A2EHN6 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=10; Trichomonas vaginalis|Rep:
Oxidoreductase, aldo/keto reductase family protein -
Trichomonas vaginalis G3
Length = 312
Score = 77.0 bits (181), Expect = 3e-13
Identities = 62/162 (38%), Positives = 89/162 (54%), Gaps = 21/162 (12%)
Frame = +1
Query: 130 IPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALE-AGYRLIDTAALYLNEDQIGAAVR-- 300
IP LG GT+L D P + + +A+E G R IDTA Y N++ IG ++
Sbjct: 3 IPQLGFGTYLAND--------PAKLKAALHYAIEECGVRHIDTAFAYYNQNVIGETLKEI 54
Query: 301 -ASG-IPREDIFIVTKLPMDNQR-DVVK-QLEKSLARLNMSYVDLYLIHNPVAFN--PGF 462
A G I RED+FI TKL + R D+V+ +L ++LA+L +SYVDL+LIH P+AF P
Sbjct: 55 FAKGKIKREDMFITTKLWCTHHRKDLVEPELHENLAQLQLSYVDLFLIHQPIAFKSLPAK 114
Query: 463 KG------------FDIVDYLDTWKGMEEAKNLGPS*IYRHI 552
G ++ +D L+T+ MEE + G + RHI
Sbjct: 115 DGTMMPKDEKGKIQYEQIDILETYHAMEECQKKG---LTRHI 153
>UniRef50_A6RKL9 Cluster: Putative uncharacterized protein; n=3;
Sclerotiniaceae|Rep: Putative uncharacterized protein -
Botryotinia fuckeliana B05.10
Length = 360
Score = 77.0 bits (181), Expect = 3e-13
Identities = 48/134 (35%), Positives = 77/134 (57%), Gaps = 7/134 (5%)
Frame = +1
Query: 127 SIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGAAV--- 297
S P +G GT+ +V P ++ + V +A+E GYR ID AA+Y NE +G +
Sbjct: 38 SQPLIGFGTW-------NLKVSPENTTEAVAYAIEIGYRQIDCAAVYGNEVAVGRGIEEG 90
Query: 298 -RASGIPREDIFIVTKLPMDNQ---RDVVKQLEKSLARLNMSYVDLYLIHNPVAFNPGFK 465
+ +G+ REDI++ +KL D+ +V K L ++L L + Y+DLYLIH P+ F+
Sbjct: 91 LKRAGLKREDIWVTSKLWNDHHGSYENVEKGLNQTLQDLGLEYLDLYLIHWPIGFSS--N 148
Query: 466 GFDIVDYLDTWKGM 507
G +D++ T+K M
Sbjct: 149 GAKNLDHVQTYKSM 162
>UniRef50_A4RQH8 Cluster: Predicted protein; n=2; Ostreococcus|Rep:
Predicted protein - Ostreococcus lucimarinus CCE9901
Length = 337
Score = 76.6 bits (180), Expect = 4e-13
Identities = 51/128 (39%), Positives = 72/128 (56%), Gaps = 8/128 (6%)
Frame = +1
Query: 100 SKISLNDGNS--IPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN 273
S I +ND N IP +GLGT+ + +P + V+ AL AGY +D AA Y N
Sbjct: 4 STILVNDANGLRIPRVGLGTW---------KARPNEVRDAVRDALGAGYAHVDCAAAYAN 54
Query: 274 EDQIGAAVRAS----GIPREDIFIVTKLPMDNQ--RDVVKQLEKSLARLNMSYVDLYLIH 435
E ++G A+R + RED+F+ +KL D + RDV + L +L L + Y+DLYLIH
Sbjct: 55 ESEVGEALREAFERGDAKREDVFVTSKLWNDRRRPRDVREALMTTLNDLGVGYLDLYLIH 114
Query: 436 NPVAFNPG 459
PVA+ G
Sbjct: 115 WPVAWKRG 122
>UniRef50_Q7PLK6 Cluster: CG40064-PA; n=1; Drosophila
melanogaster|Rep: CG40064-PA - Drosophila melanogaster
(Fruit fly)
Length = 361
Score = 76.6 bits (180), Expect = 4e-13
Identities = 50/122 (40%), Positives = 65/122 (53%), Gaps = 17/122 (13%)
Frame = +1
Query: 214 VKWALEAGYRLIDTAALYLNEDQIGAAVRAS----GIPREDIFIVTKL--PMDNQRDVVK 375
V A+E G+R DTA Y NE +IG A+R I RE+IF+ TKL + RDV +
Sbjct: 50 VHCAIETGFRHFDTAYYYENEKEIGEALRTQIKMGNISRENIFLTTKLWNTHHDPRDVRR 109
Query: 376 QLEKSLARLNMSYVDLYLIHNPVAFN-------PGFKGFDI----VDYLDTWKGMEEAKN 522
EK L L SY+DLYL+H PV + G ++ +DYLDTW+ ME
Sbjct: 110 ICEKQLELLGFSYIDLYLMHFPVGYKYVCDEILMPMSGDELQTVEIDYLDTWRAMENLVK 169
Query: 523 LG 528
LG
Sbjct: 170 LG 171
>UniRef50_Q5KD52 Cluster: Oxidoreductase, putative; n=1;
Filobasidiella neoformans|Rep: Oxidoreductase, putative
- Cryptococcus neoformans (Filobasidiella neoformans)
Length = 321
Score = 76.6 bits (180), Expect = 4e-13
Identities = 50/147 (34%), Positives = 82/147 (55%), Gaps = 3/147 (2%)
Frame = +1
Query: 103 KISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAA---LYLN 273
+I+LNDG+ IPA+ GT+ K KEV P V A++ G+ IDTA +Y N
Sbjct: 5 EITLNDGHRIPAIAFGTW-----KIPKEVTPFQ----VGQAIDVGFDHIDTAQGRIVYHN 55
Query: 274 EDQIGAAVRASGIPREDIFIVTKLPMDNQRDVVKQLEKSLARLNMSYVDLYLIHNPVAFN 453
E+++G A++ SG+ R +++ TK + + + + +SL +L + Y+DLYLIH+P
Sbjct: 56 EEEVGQAIKESGLSRNQLWVTTKWSGIDGKGARQSIGESLEKLGLEYLDLYLIHSPQVTK 115
Query: 454 PGFKGFDIVDYLDTWKGMEEAKNLGPS 534
KG L+T + + K++G S
Sbjct: 116 GDIKG--AWKELETLQKEGKTKSIGVS 140
>UniRef50_A3LTU8 Cluster: D-arabinose dehydrogenase; n=5;
Saccharomycetales|Rep: D-arabinose dehydrogenase -
Pichia stipitis (Yeast)
Length = 326
Score = 76.6 bits (180), Expect = 4e-13
Identities = 52/118 (44%), Positives = 70/118 (59%), Gaps = 4/118 (3%)
Frame = +1
Query: 112 LNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGA 291
L++G +IPALGLGT D P + ++ V A++AGYR IDTA Y E+ IG
Sbjct: 12 LSNGKTIPALGLGTVPPED--------PHELKEQVITAVKAGYRHIDTAWYYGTEEYIGQ 63
Query: 292 AVRA---SGI-PREDIFIVTKLPMDNQRDVVKQLEKSLARLNMSYVDLYLIHNPVAFN 453
A++ GI RED+FI TK+ R+ K L+KSLA L + YVDL+L H PV +
Sbjct: 64 ALKQLFEEGIVKREDLFITTKVWPSFWRNPEKSLDKSLADLGLDYVDLFLQHWPVVLH 121
>UniRef50_Q8G7K9 Cluster: Dehydrogenase or reductase protein; n=4;
Bifidobacterium|Rep: Dehydrogenase or reductase protein
- Bifidobacterium longum
Length = 289
Score = 76.2 bits (179), Expect = 5e-13
Identities = 53/123 (43%), Positives = 72/123 (58%), Gaps = 7/123 (5%)
Frame = +1
Query: 106 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 285
I+L DG+SIP +GLG L D++G V V+ ALEAGYR ID AA Y NE +
Sbjct: 14 IALKDGHSIPQVGLGV-LRIDDEGVVPV--------VESALEAGYRHIDGAAGYNNEAGV 64
Query: 286 GAAVRAS----GIPREDIFIVTKLPMDNQR---DVVKQLEKSLARLNMSYVDLYLIHNPV 444
G A+ AS G RE +++ TKL D+Q+ +K + SL L + YVD+Y+IH P
Sbjct: 65 GRALAASGYNKGAKRETLWVTTKL-RDSQQGYDSALKAFDNSLKLLQLDYVDMYMIHWPT 123
Query: 445 AFN 453
F+
Sbjct: 124 PFD 126
>UniRef50_Q5FKI1 Cluster: Reductase-dehydrogenase; n=1;
Lactobacillus acidophilus|Rep: Reductase-dehydrogenase -
Lactobacillus acidophilus
Length = 271
Score = 76.2 bits (179), Expect = 5e-13
Identities = 49/145 (33%), Positives = 73/145 (50%), Gaps = 4/145 (2%)
Frame = +1
Query: 106 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 285
+ LN+G IP + LGT+L + + K V+ A+ GYR DTA Y NE +
Sbjct: 7 VILNNGEKIPQIQLGTWL---------INNDEVNKVVRQAVNIGYRGFDTAKDYGNESGV 57
Query: 286 GAAVRASGIPREDIFIVTKLP--MDNQRDVVKQLEKSLARLNMSYVDLYLIHNPVAFNPG 459
G + S I R DIF+ TKLP + + K ++ +L + + Y+DL LIH+P +
Sbjct: 58 GKGIWNSDIERSDIFLTTKLPTAVKDYEGTKKAIDAALDKFGLEYIDLLLIHSPQPWIEV 117
Query: 460 FKGFD--IVDYLDTWKGMEEAKNLG 528
+ D L+ W+ MEEA G
Sbjct: 118 NRTNDRHFKGNLENWRAMEEAVKAG 142
>UniRef50_A3UJS6 Cluster: Oxidoreductase; n=3;
Alphaproteobacteria|Rep: Oxidoreductase - Oceanicaulis
alexandrii HTCC2633
Length = 275
Score = 76.2 bits (179), Expect = 5e-13
Identities = 57/153 (37%), Positives = 77/153 (50%), Gaps = 2/153 (1%)
Frame = +1
Query: 118 DGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGAAV 297
+G IP LG GT+ DE D+ + V AL+ GYR IDTA +Y NE +G
Sbjct: 8 NGADIPKLGFGTWQLEDE---------DAARGVATALKTGYRHIDTAQIYGNEAAVGDGW 58
Query: 298 RASGIPREDIFIVTKLPMDNQR--DVVKQLEKSLARLNMSYVDLYLIHNPVAFNPGFKGF 471
+ SG+ RED F+ TK+ D R D+ +++SL +L YVDL L+H PV P
Sbjct: 59 KQSGVKREDFFLTTKVWRDKFRDGDLQASVKESLDKLKTDYVDLLLLHWPVPEVP----- 113
Query: 472 DIVDYLDTWKGMEEAKNLGPS*IYRHI*LQHHT 570
+T K M E K G RHI + + T
Sbjct: 114 ----IAETMKAMNEVKEAGQ---VRHIGVSNFT 139
>UniRef50_Q2V420 Cluster: Uncharacterized protein At2g37770.1; n=1;
Arabidopsis thaliana|Rep: Uncharacterized protein
At2g37770.1 - Arabidopsis thaliana (Mouse-ear cress)
Length = 283
Score = 76.2 bits (179), Expect = 5e-13
Identities = 55/150 (36%), Positives = 75/150 (50%), Gaps = 11/150 (7%)
Frame = +1
Query: 112 LNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGA 291
LN G P++GLGT+ + PG V A++ GYR ID A +Y NE +IGA
Sbjct: 10 LNTGAKFPSVGLGTW---------QASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGA 60
Query: 292 AVRA----SGIPREDIFIVTKLPMDNQ--RDVVKQLEKSLARLNMSYVDLYLIHNPVAFN 453
++ + RED+FI +KL + +DV + L ++L L + YVDLYLIH P
Sbjct: 61 VLKKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIK 120
Query: 454 PGFKGFD-----IVDYLDTWKGMEEAKNLG 528
G G VD TWK ME + G
Sbjct: 121 KGSVGIKPENLLPVDIPSTWKAMEALYDSG 150
>UniRef50_Q0PGJ6 Cluster: Aldo-keto reductase; n=32;
Magnoliophyta|Rep: Aldo-keto reductase - Arabidopsis
thaliana (Mouse-ear cress)
Length = 315
Score = 76.2 bits (179), Expect = 5e-13
Identities = 55/150 (36%), Positives = 75/150 (50%), Gaps = 11/150 (7%)
Frame = +1
Query: 112 LNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGA 291
LN G P++GLGT+ + PG V A++ GYR ID A +Y NE +IGA
Sbjct: 10 LNTGAKFPSVGLGTW---------QASPGLVGDAVAAAVKIGYRHIDCAQIYGNEKEIGA 60
Query: 292 AVRA----SGIPREDIFIVTKLPMDNQ--RDVVKQLEKSLARLNMSYVDLYLIHNPVAFN 453
++ + RED+FI +KL + +DV + L ++L L + YVDLYLIH P
Sbjct: 61 VLKKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARIK 120
Query: 454 PGFKGFD-----IVDYLDTWKGMEEAKNLG 528
G G VD TWK ME + G
Sbjct: 121 KGSVGIKPENLLPVDIPSTWKAMEALYDSG 150
>UniRef50_Q54B70 Cluster: Aldehyde reductase; n=2; Dictyostelium
discoideum|Rep: Aldehyde reductase - Dictyostelium
discoideum AX4
Length = 297
Score = 76.2 bits (179), Expect = 5e-13
Identities = 54/153 (35%), Positives = 81/153 (52%), Gaps = 14/153 (9%)
Frame = +1
Query: 112 LNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGA 291
L+ G+ IP +G GT+ K + + K V+ AL+AGYR ID AA+YLNE ++G
Sbjct: 7 LSSGHKIPLVGFGTW-----KAETTLVG----KAVEVALDAGYRHIDCAAVYLNEKEVGE 57
Query: 292 A-----VRASGIPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIHNPVAF 450
A + + RED+FI +KL + V LE++L+ L + Y+DLYL+H PVAF
Sbjct: 58 AFTKKFTTEATVKREDVFITSKLWNTFHKKEHVRPALERTLSDLGLQYLDLYLVHWPVAF 117
Query: 451 NPGFKGF-------DIVDYLDTWKGMEEAKNLG 528
+ V +TW+ ME+ + G
Sbjct: 118 EYTSNDIQTSGSTQEFVSIRETWEEMEKLVDAG 150
>UniRef50_UPI0000498F1F Cluster: oxidoreductase, aldo/keto reductase
family; n=2; Entamoeba histolytica HM-1:IMSS|Rep:
oxidoreductase, aldo/keto reductase family - Entamoeba
histolytica HM-1:IMSS
Length = 305
Score = 75.8 bits (178), Expect = 7e-13
Identities = 50/143 (34%), Positives = 81/143 (56%), Gaps = 8/143 (5%)
Frame = +1
Query: 109 SLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIG 288
+LN+G IP LGLGT++ + G+ K V+ A++ GYR ID A Y NE ++G
Sbjct: 6 TLNNGYKIPKLGLGTWMSAN---------GEVGKAVEIAIKNGYRHIDCAKAYGNEKEVG 56
Query: 289 AAVR---ASG-IPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIHNPVAF 450
++ A G + RE++F+ TKL ++ DV +SL +L + Y+DLY+IH P+
Sbjct: 57 DGIKSAIAKGYVKREELFVTTKLWSTDKHKEDVRPACLESLKKLQLEYLDLYIIHIPLTA 116
Query: 451 NPGFKGF--DIVDYLDTWKGMEE 513
+ F +I+ +TW+ ME+
Sbjct: 117 DKKTGEFTEEIIPIEETWREMEK 139
>UniRef50_UPI000065D0BD Cluster: Homolog of Homo sapiens "AKR1B1
protein.; n=1; Takifugu rubripes|Rep: Homolog of Homo
sapiens "AKR1B1 protein. - Takifugu rubripes
Length = 330
Score = 75.8 bits (178), Expect = 7e-13
Identities = 51/119 (42%), Positives = 71/119 (59%), Gaps = 6/119 (5%)
Frame = +1
Query: 106 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 285
++LN G +P LGLGT+ K K G + + VK A+ AGYR IDTA +Y NE ++
Sbjct: 5 VTLNTGALMPVLGLGTW-----KSGK----GVTTEAVKVAIGAGYRHIDTAYVYENETEV 55
Query: 286 GAAVRA----SGIPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIHNPV 444
GA V+A + RE++FIV+KL V EK+L+ LN+ YVDLYL+H P+
Sbjct: 56 GAGVQAMIDQGVVKREELFIVSKLWCTFHTPSLVRGACEKTLSSLNLDYVDLYLMHFPM 114
>UniRef50_Q8EUH6 Cluster: Oxidoreductase; n=1; Mycoplasma
penetrans|Rep: Oxidoreductase - Mycoplasma penetrans
Length = 285
Score = 75.8 bits (178), Expect = 7e-13
Identities = 46/137 (33%), Positives = 71/137 (51%), Gaps = 2/137 (1%)
Frame = +1
Query: 106 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 285
I L +G +P +GLG + E + + +K + GYR+IDTA +Y NE+ +
Sbjct: 4 IKLANGLHMPIIGLGVYKAEGENCENTI--------IKAIDDYGYRMIDTAQVYFNEEFV 55
Query: 286 GAAVRASGIPREDIFIVTKLPMDN--QRDVVKQLEKSLARLNMSYVDLYLIHNPVAFNPG 459
G A++ + I REDIFI TK+ + N + + + KSL +L +Y+DL L+H P
Sbjct: 56 GNAIKQTKIKREDIFITTKVWISNYGYNNTMYSISKSLKKLQTNYIDLVLLHQPFG---- 111
Query: 460 FKGFDIVDYLDTWKGME 510
DY WK +E
Sbjct: 112 -------DYYSAWKALE 121
>UniRef50_Q5TNP1 Cluster: ENSANGP00000029046; n=2; Culicidae|Rep:
ENSANGP00000029046 - Anopheles gambiae str. PEST
Length = 331
Score = 75.8 bits (178), Expect = 7e-13
Identities = 50/117 (42%), Positives = 67/117 (57%), Gaps = 7/117 (5%)
Frame = +1
Query: 112 LNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGA 291
LN G IP G GT+ GQ+ + + + +ALEAGYR IDTA +Y NE+ IG
Sbjct: 36 LNTGFDIPLAGFGTY---QIHGQELIY-----QVLDYALEAGYRHIDTAVVYRNEEYIGT 87
Query: 292 AVRA----SGIPREDIFIVTKLPMDNQRD---VVKQLEKSLARLNMSYVDLYLIHNP 441
A++ + REDIFI +KL + +D V + + KSLA L Y+DLYLIH P
Sbjct: 88 ALKTLLPKYNLKREDIFITSKLISQSGKDEAFVEQMVRKSLANLQTDYLDLYLIHWP 144
>UniRef50_Q5UX52 Cluster: Oxidoreductase aldo/keto reductase family;
n=1; Haloarcula marismortui|Rep: Oxidoreductase
aldo/keto reductase family - Haloarcula marismortui
(Halobacterium marismortui)
Length = 274
Score = 75.8 bits (178), Expect = 7e-13
Identities = 45/109 (41%), Positives = 62/109 (56%), Gaps = 2/109 (1%)
Frame = +1
Query: 121 GNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGAAVR 300
G S+PALGLGT+ ++ + V+ AL GYR IDTA Y NE Q+G +
Sbjct: 8 GTSVPALGLGTW---------QLTGQSCRETVETALGMGYRHIDTAQAYGNERQVGLGMD 58
Query: 301 ASGIPREDIFIVTKLPMDN--QRDVVKQLEKSLARLNMSYVDLYLIHNP 441
A+ + RED+F+ TKL N +R V + +SL +L Y+DL LIH P
Sbjct: 59 AAAVDREDVFLTTKLDGSNRDERSVRRSTRESLNKLGTDYLDLLLIHWP 107
>UniRef50_Q8CI22 Cluster: 2310005E10Rik protein; n=30;
Tetrapoda|Rep: 2310005E10Rik protein - Mus musculus
(Mouse)
Length = 316
Score = 75.4 bits (177), Expect = 9e-13
Identities = 55/160 (34%), Positives = 83/160 (51%), Gaps = 16/160 (10%)
Frame = +1
Query: 97 ASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNE 276
A+ ++L G +P +GLGT+ + P + VK A++AGYR ID A +Y NE
Sbjct: 2 AAFVTLLTGAKMPIVGLGTW---------KSPPAKVREAVKVAIDAGYRHIDCAYVYQNE 52
Query: 277 DQIGAAVRAS----GIPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIHN 438
++G A++ + RED+FIV+KL + V K + +L+ L + Y+DLYLIH
Sbjct: 53 SEVGEAIQEKIQEKAVKREDLFIVSKLWSTFFEKSLVKKAFQNTLSDLKLDYLDLYLIHW 112
Query: 439 PVAFNPG-------FKGFDI---VDYLDTWKGMEEAKNLG 528
P F G KG + +LD W+ MEE + G
Sbjct: 113 PQGFQSGNVFLPTDDKGSILSSKYTFLDAWEAMEELVDQG 152
>UniRef50_Q6RZX1 Cluster: Gld1; n=22; Pezizomycotina|Rep: Gld1 -
Trichoderma atroviride (Hypocrea atroviridis)
Length = 327
Score = 75.4 bits (177), Expect = 9e-13
Identities = 46/120 (38%), Positives = 67/120 (55%), Gaps = 7/120 (5%)
Frame = +1
Query: 109 SLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIG 288
+LN G IPA+G GTF +G K G++ V AL+ GYR +D A YLNED++G
Sbjct: 16 TLNTGAKIPAVGFGTFAN---EGAK----GETYAAVTKALDVGYRHLDCAWFYLNEDEVG 68
Query: 289 AAV-----RASGIPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIHNPVA 447
A+ R + R+D+FI TK+ + DV + S L + Y+DL+L+H P+A
Sbjct: 69 DAIRDFLARRPDVTRKDLFICTKVWNHLHEPEDVKWSAKNSCENLKVDYIDLFLVHWPIA 128
>UniRef50_Q5B5R6 Cluster: Putative uncharacterized protein; n=1;
Emericella nidulans|Rep: Putative uncharacterized
protein - Emericella nidulans (Aspergillus nidulans)
Length = 682
Score = 75.4 bits (177), Expect = 9e-13
Identities = 48/122 (39%), Positives = 66/122 (54%)
Frame = +1
Query: 67 LSEATTGGGKASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRL 246
L +T + LN G IPA+GLGT ++ KPG + V+ AL+ GYR
Sbjct: 401 LFTSTQARNRDRSFRLNTGALIPAVGLGT--------RRAQKPGLVYRAVRSALKTGYRH 452
Query: 247 IDTAALYLNEDQIGAAVRASGIPREDIFIVTKLPMDNQRDVVKQLEKSLARLNMSYVDLY 426
IDTA E +IG AV+ SG+ R +++ TKL V + L+ SL+ L M YVDLY
Sbjct: 453 IDTAMSSGVEHEIGQAVKDSGVSRSQVWVTTKLDNRWHTRVQEALDMSLSELGMDYVDLY 512
Query: 427 LI 432
L+
Sbjct: 513 LM 514
>UniRef50_Q4PAT5 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 700
Score = 75.4 bits (177), Expect = 9e-13
Identities = 45/121 (37%), Positives = 67/121 (55%), Gaps = 2/121 (1%)
Frame = +1
Query: 94 KASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN 273
+++ +L +G IP LG GT+ K KE + V A++ GYR ID A Y N
Sbjct: 8 RSANFTLANGAQIPKLGFGTW-----KMSKE----QATPAVAHAIKTGYRHIDCAWAYRN 58
Query: 274 EDQIGAAVRASGIPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIHNPVA 447
ED + A ++ +G+PR +++ +KL + V K L+ SL L Y+DLYL+H PVA
Sbjct: 59 EDAVAAGIKKAGVPRSQLWLTSKLWNSFHHPEHVEKALDASLKDLGTDYLDLYLMHWPVA 118
Query: 448 F 450
F
Sbjct: 119 F 119
>UniRef50_Q4PHK0 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 355
Score = 64.1 bits (149), Expect(2) = 9e-13
Identities = 28/65 (43%), Positives = 43/65 (66%)
Frame = +1
Query: 250 DTAALYLNEDQIGAAVRASGIPREDIFIVTKLPMDNQRDVVKQLEKSLARLNMSYVDLYL 429
D A +Y NE+++G ++ASG+PR ++F+ TK+ R L++SL RL + YVDL L
Sbjct: 80 DAAWIYGNENEVGQGIKASGVPRSELFVTTKIWCTYHRQPEACLDESLQRLGLDYVDLLL 139
Query: 430 IHNPV 444
+H PV
Sbjct: 140 VHWPV 144
Score = 31.5 bits (68), Expect(2) = 9e-13
Identities = 19/46 (41%), Positives = 26/46 (56%)
Frame = +1
Query: 112 LNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLI 249
LN G IP +GLGT+ + PG+ K V+ A++AGYR I
Sbjct: 16 LNTGAEIPVIGLGTW---------QSAPGEVAKAVESAIKAGYRHI 52
>UniRef50_Q96JD6 Cluster: Aldo-keto reductase family 1 member C-like
protein 2; n=37; Euteleostomi|Rep: Aldo-keto reductase
family 1 member C-like protein 2 - Homo sapiens (Human)
Length = 320
Score = 72.1 bits (169), Expect(2) = 9e-13
Identities = 45/115 (39%), Positives = 66/115 (57%), Gaps = 6/115 (5%)
Frame = +1
Query: 130 IPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGAAVRA-- 303
IPA+GL ++ + PG + VK A++AGYR D A Y NE ++GA +R
Sbjct: 4 IPAVGLSSW---------KASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKI 54
Query: 304 --SGIPREDIFIVTKLPMD-NQRDVVK-QLEKSLARLNMSYVDLYLIHNPVAFNP 456
+ RED+FI TKL +++ +V+ KSL L ++Y+DLYLIH P+ F P
Sbjct: 55 KEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKP 109
Score = 23.4 bits (48), Expect(2) = 9e-13
Identities = 7/11 (63%), Positives = 10/11 (90%)
Frame = +1
Query: 481 DYLDTWKGMEE 513
D+LDTW+ ME+
Sbjct: 147 DFLDTWEAMED 157
>UniRef50_Q96JD6-2 Cluster: Isoform 2 of Q96JD6 ; n=4;
Catarrhini|Rep: Isoform 2 of Q96JD6 - Homo sapiens
(Human)
Length = 263
Score = 72.1 bits (169), Expect(2) = 9e-13
Identities = 45/115 (39%), Positives = 66/115 (57%), Gaps = 6/115 (5%)
Frame = +1
Query: 130 IPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGAAVRA-- 303
IPA+GL ++ + PG + VK A++AGYR D A Y NE ++GA +R
Sbjct: 4 IPAVGLSSW---------KASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKI 54
Query: 304 --SGIPREDIFIVTKLPMD-NQRDVVK-QLEKSLARLNMSYVDLYLIHNPVAFNP 456
+ RED+FI TKL +++ +V+ KSL L ++Y+DLYLIH P+ F P
Sbjct: 55 KEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKP 109
Score = 23.4 bits (48), Expect(2) = 9e-13
Identities = 7/11 (63%), Positives = 10/11 (90%)
Frame = +1
Query: 481 DYLDTWKGMEE 513
D+LDTW+ ME+
Sbjct: 147 DFLDTWEAMED 157
>UniRef50_A4YQ04 Cluster: 2,5-diketo-D-gluconate reductase B; n=15;
Proteobacteria|Rep: 2,5-diketo-D-gluconate reductase B -
Bradyrhizobium sp. (strain ORS278)
Length = 273
Score = 74.9 bits (176), Expect = 1e-12
Identities = 48/109 (44%), Positives = 65/109 (59%), Gaps = 2/109 (1%)
Frame = +1
Query: 121 GNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGAAVR 300
G +P LGLGTF + Q V V+ AL GYR IDTA +Y NED IGAA+
Sbjct: 8 GVRLPKLGLGTF-----RMQGTV----CRDAVESALALGYRHIDTAEMYANEDAIGAALA 58
Query: 301 ASGIPREDIFIVTKL-PMDNQRDVVKQ-LEKSLARLNMSYVDLYLIHNP 441
A+ I RED+ + TK+ P + D +++ + SL +L + +VDLYLIH P
Sbjct: 59 AAQIAREDLHVTTKVWPENLAPDAIRRAFDTSLKKLRLDFVDLYLIHWP 107
>UniRef50_Q7PM68 Cluster: ENSANGP00000014386; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000014386 - Anopheles gambiae
str. PEST
Length = 310
Score = 74.9 bits (176), Expect = 1e-12
Identities = 47/123 (38%), Positives = 69/123 (56%), Gaps = 9/123 (7%)
Frame = +1
Query: 106 ISLNDGNSI--PALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNED 279
I+L+D +SI P +GLGT+ + D ++ ++ A++ GYR+ DTA Y NE
Sbjct: 7 INLSDQHSIALPTIGLGTY---------SILGADGKEAIRTAIDVGYRMFDTAVAYGNEA 57
Query: 280 QIGAAVR-----ASGIPREDIFIVTKLPMDNQRD--VVKQLEKSLARLNMSYVDLYLIHN 438
+G A+R + + R+D FI++KL R V K +L RL M YVDLYL+H
Sbjct: 58 IVGEAIREKIRECNNLTRDDFFIISKLSGSYHRQDLVEKCCRMTLDRLGMDYVDLYLMHT 117
Query: 439 PVA 447
PVA
Sbjct: 118 PVA 120
>UniRef50_Q24C22 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=4; Oligohymenophorea|Rep: Oxidoreductase,
aldo/keto reductase family protein - Tetrahymena
thermophila SB210
Length = 297
Score = 74.9 bits (176), Expect = 1e-12
Identities = 55/161 (34%), Positives = 80/161 (49%), Gaps = 5/161 (3%)
Frame = +1
Query: 85 GGGKASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAAL 264
G K ++ +G SIP +G GT+ E++ D V AL+ GY IDTA++
Sbjct: 9 GKVKVPILNFREGGSIPQIGYGTY---------ELRQNDCIIGVTEALKIGYTHIDTASV 59
Query: 265 YLNEDQIGAAVR--ASGIPREDIFIVTKLPMDNQ--RDVVKQLEKSLARLNMSYVDLYLI 432
Y NE I + A GI RED+FI +K+ Q K ++ L RLN+ Y+D LI
Sbjct: 60 YRNEQDIAKVIHNPAYGIKREDLFITSKISPGEQGYEQAKKAVQDMLTRLNIKYLDCVLI 119
Query: 433 HNP-VAFNPGFKGFDIVDYLDTWKGMEEAKNLGPS*IYRHI 552
H P V+ P + L+TWK + E + G + +HI
Sbjct: 120 HWPGVSKLPPNDPKNAQIRLETWKALIELRKAG---VIKHI 157
>UniRef50_Q9P6D3 Cluster: Related to aldo-keto reductase YPR1; n=10;
Pezizomycotina|Rep: Related to aldo-keto reductase YPR1
- Neurospora crassa
Length = 322
Score = 74.9 bits (176), Expect = 1e-12
Identities = 52/150 (34%), Positives = 73/150 (48%), Gaps = 9/150 (6%)
Frame = +1
Query: 106 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVK--------WALEAGYRLIDTAA 261
+ L+DGN IP LG G G K GDS + AL AGY +D A
Sbjct: 27 LKLSDGNEIPMLGYGL-------GTANYKSGDSADTISEPIVNATLTALNAGYAHLDGAE 79
Query: 262 LYLNEDQIGAAVRASGIPREDIFIVTKLPMDNQRDVVKQLEKSLARLNMSYVDLYLIHNP 441
+Y NE ++G A+ S +PR ++I TK + V + +SL +L + YVDLYL+H+P
Sbjct: 80 VYGNEVELGRAIAQSKLPRSSLYITTKTIVRAGDTVTQSFNRSLEKLGLDYVDLYLLHSP 139
Query: 442 -VAFNPGFKGFDIVDYLDTWKGMEEAKNLG 528
A NP W+ ME+ K+ G
Sbjct: 140 FFAKNP-------EQLQAAWREMEKIKDSG 162
>UniRef50_Q76L37 Cluster: Conjugated polyketone reductase C1; n=3;
Saccharomycetales|Rep: Conjugated polyketone reductase
C1 - Candida parapsilosis (Yeast)
Length = 304
Score = 74.5 bits (175), Expect = 2e-12
Identities = 49/151 (32%), Positives = 78/151 (51%), Gaps = 9/151 (5%)
Frame = +1
Query: 103 KISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQ 282
+ L++GN IPA+ GT + ++G ++ ++ AL +G+R ID A +Y +
Sbjct: 7 EFKLSNGNKIPAVAFGTGTKYFKRGHNDLDK-QLIGTLELALRSGFRHIDGAEIYGTNKE 65
Query: 283 IGAAVRASGIPREDIFIVTKLPMDN---------QRDVVKQLEKSLARLNMSYVDLYLIH 435
IG A++ G+ R+D+FI K N ++ L+ L L + YVDLYLIH
Sbjct: 66 IGIALKNVGLNRKDVFITDKYNSGNHTYDGKHSKHQNPYNALKADLEDLGLEYVDLYLIH 125
Query: 436 NPVAFNPGFKGFDIVDYLDTWKGMEEAKNLG 528
P + GFD+V + W+ +E AKN G
Sbjct: 126 FPY-ISEKSHGFDLV---EAWRYLERAKNEG 152
>UniRef50_P38115 Cluster: D-arabinose dehydrogenase [NAD(P)+] heavy
chain; n=3; Saccharomycetaceae|Rep: D-arabinose
dehydrogenase [NAD(P)+] heavy chain - Saccharomyces
cerevisiae (Baker's yeast)
Length = 344
Score = 74.5 bits (175), Expect = 2e-12
Identities = 49/118 (41%), Positives = 66/118 (55%), Gaps = 4/118 (3%)
Frame = +1
Query: 109 SLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIG 288
SLN+G IPALGLGT K ++++ VK A++AGYR IDTA Y E +G
Sbjct: 26 SLNNGVRIPALGLGT-------ANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVG 78
Query: 289 AAVRA----SGIPREDIFIVTKLPMDNQRDVVKQLEKSLARLNMSYVDLYLIHNPVAF 450
A++ I RED+FI TK+ +V + L +SL L + YVDL L H P+ F
Sbjct: 79 EAIKELLEDGSIKREDLFITTKVWPVLWDEVDRSLNESLKALGLEYVDLLLQHWPLCF 136
>UniRef50_Q7NB44 Cluster: ARA1; n=3; Firmicutes|Rep: ARA1 -
Mycoplasma gallisepticum
Length = 289
Score = 74.1 bits (174), Expect = 2e-12
Identities = 53/148 (35%), Positives = 75/148 (50%), Gaps = 3/148 (2%)
Frame = +1
Query: 79 TTGGGKASKISLNDGN-SIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDT 255
TT K K +L N +P++G GT+ D K E VK ALE GYR +D
Sbjct: 4 TTKKIKVMKYNLLANNYKMPSIGFGTYKLEDGKQTVEA--------VKTALEVGYRHLDC 55
Query: 256 AALYLNEDQIGAAVRASGIPREDIFIVTKLPMDNQ--RDVVKQLEKSLARLNMSYVDLYL 429
A +Y N+ + ++ SG+ R++IFI +K+ D++ K K L L++ Y+DL L
Sbjct: 56 AEIYENQLSVSQGIKLSGVNRKEIFITSKIWNDDKGYESTKKAFHKILKDLDLEYLDLLL 115
Query: 430 IHNPVAFNPGFKGFDIVDYLDTWKGMEE 513
IH P+ GFK TWK MEE
Sbjct: 116 IHWPI--GKGFKDNWQEVNAQTWKAMEE 141
>UniRef50_A1CAM7 Cluster: Aldo-keto reductase, putative; n=9;
Dikarya|Rep: Aldo-keto reductase, putative - Aspergillus
clavatus
Length = 283
Score = 74.1 bits (174), Expect = 2e-12
Identities = 38/85 (44%), Positives = 55/85 (64%), Gaps = 4/85 (4%)
Frame = +1
Query: 223 ALEAGYRLIDTAALYLNEDQIGAAVRASGIPREDIFIVTKL--PMDNQRDVVKQLEKSLA 396
AL+AGYR IDTA Y NE ++G A+R SGIPR D+F+ TK+ P + K+L +S+
Sbjct: 42 ALQAGYRNIDTAQFYANEQEVGEALRTSGIPRSDVFVTTKILSPAGSPEATYKKLLESVE 101
Query: 397 RL--NMSYVDLYLIHNPVAFNPGFK 465
++ YVDL+LIH+ + + G K
Sbjct: 102 KIGGENGYVDLFLIHSSSSGSAGRK 126
>UniRef50_UPI00006CD296 Cluster: oxidoreductase, aldo/keto reductase
family protein; n=1; Tetrahymena thermophila SB210|Rep:
oxidoreductase, aldo/keto reductase family protein -
Tetrahymena thermophila SB210
Length = 295
Score = 73.7 bits (173), Expect = 3e-12
Identities = 51/145 (35%), Positives = 73/145 (50%), Gaps = 6/145 (4%)
Frame = +1
Query: 112 LNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGA 291
L +G+ +P GLGT+ K V + ++ AL+ GYR IDTA +Y NE QIG
Sbjct: 10 LCNGSKLPVFGLGTY--------KVVSKEEMVTFLRTALDLGYRHIDTAIMYENEKQIGD 61
Query: 292 AV----RASGIPREDIFIVTKLPMDNQRDVVKQLEKSLARLNMSYVDLYLIHNPVAFNPG 459
A+ + RED+F+VTKL + V Q+ +SL L +Y+DLYL+H A +P
Sbjct: 62 ALQEIYKEGKYKREDLFLVTKLFSNKNTKVEDQVRQSLQNLQTNYIDLYLLH--YASSPP 119
Query: 460 FKGFDIV--DYLDTWKGMEEAKNLG 528
F++ W EE G
Sbjct: 120 TDQFELTHKPVFQVWAEFEELVQKG 144
>UniRef50_Q9VTL0 Cluster: CG6083-PA; n=4; Diptera|Rep: CG6083-PA -
Drosophila melanogaster (Fruit fly)
Length = 322
Score = 73.7 bits (173), Expect = 3e-12
Identities = 53/157 (33%), Positives = 86/157 (54%), Gaps = 18/157 (11%)
Frame = +1
Query: 112 LNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGA 291
L++G ++P LGLGT+ + EV + VK A++ GYR D A +Y NE Q+GA
Sbjct: 8 LSNGKNMPMLGLGTW-----RSPPEVVT----QAVKDAIDIGYRHFDCAHIYGNEAQVGA 58
Query: 292 AVR----ASGIPREDIFIVTKL-PMDNQRDVVK-QLEKSLARLNMSYVDLYLIHNPVAFN 453
A+R + R+++FI +KL ++ D+V+ E S+ L + Y++LYL+H P+A+
Sbjct: 59 ALREKMDEGVVTRDELFITSKLWNTHHKPDLVRPACETSIRNLGVKYLNLYLMHWPMAYK 118
Query: 454 PGF------------KGFDIVDYLDTWKGMEEAKNLG 528
G F+ +DY+DTW+ ME + G
Sbjct: 119 SGSDNLYPTCPDTNKAAFEDIDYVDTWRAMENLVDEG 155
>UniRef50_Q5BLA6 Cluster: Zgc:110782; n=2; Danio rerio|Rep:
Zgc:110782 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 287
Score = 73.3 bits (172), Expect = 4e-12
Identities = 50/131 (38%), Positives = 71/131 (54%), Gaps = 5/131 (3%)
Frame = +1
Query: 106 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 285
+ L G +P LGLGT+ D + K+ V AL+AGYR DTAA+Y NE +
Sbjct: 6 VRLMSGTQMPLLGLGTYKLQDHEQLKQ--------SVSCALQAGYRAFDTAAVYGNEAHL 57
Query: 286 GAAVR----ASGIPREDIFIVTKL-PMDNQRDVVKQLEKSLARLNMSYVDLYLIHNPVAF 450
G ++ G+ RED+FI++KL P D+ + +SL +L+ Y+DLYLIH
Sbjct: 58 GQVLKELLPKYGLIREDVFIISKLAPSDHGLRAKEGCLRSLEQLDCEYIDLYLIH----- 112
Query: 451 NPGFKGFDIVD 483
PG +G D D
Sbjct: 113 WPGMEGLDPED 123
>UniRef50_Q2BBN7 Cluster: YvgN; n=1; Bacillus sp. NRRL B-14911|Rep:
YvgN - Bacillus sp. NRRL B-14911
Length = 268
Score = 73.3 bits (172), Expect = 4e-12
Identities = 47/146 (32%), Positives = 70/146 (47%), Gaps = 5/146 (3%)
Frame = +1
Query: 106 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 285
I+LN+G +P +G GT E + + A+E GYR ID A +Y NE+ +
Sbjct: 4 ITLNNGLEMPIVGTGTNTYGKENNDYNGDLTNEIPELASAIELGYRSIDAAIMYRNEELV 63
Query: 286 GAAVRASGIPREDIFIVTKLPMDNQRDVVKQ-----LEKSLARLNMSYVDLYLIHNPVAF 450
G+ + S +PRE+ FI TK+P + K+ ++ SL Y+DL LIH P+
Sbjct: 64 GSVLAESKVPREEFFITTKIPASEEYISSKEATRAAIDNSLKNFQTDYLDLLLIHFPIE- 122
Query: 451 NPGFKGFDIVDYLDTWKGMEEAKNLG 528
D V +TW+ EE G
Sbjct: 123 -------DKVQLKNTWEVFEEYYEAG 141
>UniRef50_Q572D2 Cluster: Aldo-keto reductase, putative; n=1;
Phytophthora infestans|Rep: Aldo-keto reductase,
putative - Phytophthora infestans (Potato late blight
fungus)
Length = 255
Score = 73.3 bits (172), Expect = 4e-12
Identities = 46/112 (41%), Positives = 63/112 (56%), Gaps = 2/112 (1%)
Frame = +1
Query: 112 LNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGA 291
L G IP +GLG + Q E P ++ + +L+ GYR IDTA +Y NE+ +G
Sbjct: 10 LPSGARIPMIGLGVY-------QSEPGP-ETYNAILTSLKLGYRHIDTAEIYGNEEDVGR 61
Query: 292 AVRASGIPREDIFIVTKLPMDN--QRDVVKQLEKSLARLNMSYVDLYLIHNP 441
AVR SGIPRE+IF+ TKL N + + S RL + Y+ LYL+H P
Sbjct: 62 AVRDSGIPREEIFVTTKLFTTNWGYSKALAAGKASNDRLGIVYIYLYLLHAP 113
>UniRef50_Q01J82 Cluster: OSIGBa0152K17.5 protein; n=28;
Magnoliophyta|Rep: OSIGBa0152K17.5 protein - Oryza
sativa (Rice)
Length = 323
Score = 73.3 bits (172), Expect = 4e-12
Identities = 54/150 (36%), Positives = 70/150 (46%), Gaps = 14/150 (9%)
Frame = +1
Query: 121 GNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGAAV- 297
G +PA+G+GT P ALE G+R DTAALY E +G A+
Sbjct: 14 GRPMPAVGVGT------ADSAATSPETKRGAALAALEVGFRHFDTAALYGTEAPLGEAIA 67
Query: 298 ----RASGIPREDIFIVTKLPMDNQRD--VVKQLEKSLARLNMSYVDLYLIHNPVAFNPG 459
R RE++F+ TKL V+ L +SL L M YVDLYL+H P++ PG
Sbjct: 68 EATRRGLVASREEVFVTTKLWCTQCHPGLVLPSLRESLRNLQMEYVDLYLVHWPISVKPG 127
Query: 460 -----FKGFDIV--DYLDTWKGMEEAKNLG 528
K D V D+ W+ MEE LG
Sbjct: 128 PPMLPVKREDAVPFDFEGVWRAMEECHRLG 157
>UniRef50_Q8SSK6 Cluster: ALDOSE REDUCTASE; n=1; Encephalitozoon
cuniculi|Rep: ALDOSE REDUCTASE - Encephalitozoon
cuniculi
Length = 301
Score = 73.3 bits (172), Expect = 4e-12
Identities = 56/153 (36%), Positives = 78/153 (50%), Gaps = 14/153 (9%)
Frame = +1
Query: 112 LNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGA 291
LN+G IP +GLGT+ G +++ E ++ AL GYR IDTA +Y NE IG
Sbjct: 8 LNNGKEIPTVGLGTW-GMEDEAVLE-------GAIRNALSLGYRHIDTAFIYGNEKMIGN 59
Query: 292 AVRA----SGIPREDIFIVTKLPMDNQRDVVKQLEKSLARLNMSYVDLYLIHNPVAFNPG 459
++ + R+D+FI +KL L +SL L M YVDLYLIH PV F+P
Sbjct: 60 ILKKLFDEGVVQRKDLFITSKLWNTFHGCPEDGLRRSLNDLQMDYVDLYLIHWPVTFDPA 119
Query: 460 FKG--------FDI--VDYLDTWKGMEEAKNLG 528
G +++ D + WK ME +LG
Sbjct: 120 PDGTVESCGKKYNVGKFDAVGVWKKMEALVDLG 152
>UniRef50_A2QB88 Cluster: Contig An01c0460, complete genome.
precursor; n=1; Aspergillus niger|Rep: Contig An01c0460,
complete genome. precursor - Aspergillus niger
Length = 351
Score = 73.3 bits (172), Expect = 4e-12
Identities = 50/119 (42%), Positives = 69/119 (57%), Gaps = 8/119 (6%)
Frame = +1
Query: 127 SIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGAAVRAS 306
+ PA+GLGTF G + G + VK + V AL GYR IDTA Y NE ++G A++ S
Sbjct: 45 TFPAVGLGTFQG--DAGNRGVK-----EAVLQALRCGYRHIDTATAYGNEIEVGEAIKES 97
Query: 307 GIPREDIFIVTKLPMDNQR--DVVKQLEKSLARLNMSY---VDLYLIHN---PVAFNPG 459
IPRE+I + TKL R DV + L+ SL RL ++Y + LY + P A++PG
Sbjct: 98 RIPREEIIVTTKLAQTWHRVSDVERALDLSLERLQLNYGLSMHLYSASSYSVPHAYSPG 156
>UniRef50_UPI0000E45E29 Cluster: PREDICTED: similar to aldose
reductase; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to aldose reductase -
Strongylocentrotus purpuratus
Length = 274
Score = 72.9 bits (171), Expect = 5e-12
Identities = 41/93 (44%), Positives = 59/93 (63%), Gaps = 6/93 (6%)
Frame = +1
Query: 190 KPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGAAVR----ASGIPREDIFIVTKLPMDN 357
KPG E VK A++ GYR ID A +Y NE ++GA ++ A+ + REDIFI +KL +
Sbjct: 8 KPGQVEAAVKAAIDCGYRHIDCAHVYGNEAEVGAGLKEKFDANVVKREDIFITSKLWNNK 67
Query: 358 QR--DVVKQLEKSLARLNMSYVDLYLIHNPVAF 450
DV + + +L L +SYVDLYL+H P+A+
Sbjct: 68 HHPDDVEQACDITLKNLQLSYVDLYLMHWPMAY 100
>UniRef50_Q15NA5 Cluster: Aldo/keto reductase; n=2;
Gammaproteobacteria|Rep: Aldo/keto reductase -
Pseudoalteromonas atlantica (strain T6c / BAA-1087)
Length = 273
Score = 72.9 bits (171), Expect = 5e-12
Identities = 44/115 (38%), Positives = 65/115 (56%), Gaps = 2/115 (1%)
Frame = +1
Query: 175 GQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGAAVRASGIPREDIFIVTKLPMD 354
G +K D++ V+ AL+ GYR IDTA Y NE ++G A+ AS I R ++F+ TK+ D
Sbjct: 17 GTYRLKGDDAKLAVENALDVGYRHIDTAQAYENEAEVGDAISASKISRGELFVTTKVWFD 76
Query: 355 N--QRDVVKQLEKSLARLNMSYVDLYLIHNPVAFNPGFKGFDIVDYLDTWKGMEE 513
N + ++ SL +LN YVDL L+H P +P K + +YL K +E
Sbjct: 77 NLSADKFITSVQNSLTQLNTDYVDLLLVHWP---SPDNK-VSMAEYLKELKACKE 127
>UniRef50_Q6CWB9 Cluster: Similarities with sp|Q12458 Saccharomyces
cerevisiae YDR368w YPR1; n=1; Kluyveromyces lactis|Rep:
Similarities with sp|Q12458 Saccharomyces cerevisiae
YDR368w YPR1 - Kluyveromyces lactis (Yeast) (Candida
sphaerica)
Length = 127
Score = 72.9 bits (171), Expect = 5e-12
Identities = 36/75 (48%), Positives = 46/75 (61%)
Frame = +1
Query: 262 LYLNEDQIGAAVRASGIPREDIFIVTKLPMDNQRDVVKQLEKSLARLNMSYVDLYLIHNP 441
+Y NE +G +R SGIPRE+IF+ TKL QRD L +SL RL + YVDL+LIH P
Sbjct: 1 MYGNETAVGKGIRDSGIPREEIFVTTKLWNTQQRDPASALNESLERLGLDYVDLFLIHWP 60
Query: 442 VAFNPGFKGFDIVDY 486
V P +I+ Y
Sbjct: 61 VPLKPVGGSKNILKY 75
>UniRef50_UPI00015B5BD7 Cluster: PREDICTED: similar to aldo-keto
reductase; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to aldo-keto reductase - Nasonia vitripennis
Length = 310
Score = 72.5 bits (170), Expect = 7e-12
Identities = 47/121 (38%), Positives = 71/121 (58%), Gaps = 7/121 (5%)
Frame = +1
Query: 106 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 285
+ LN+G +P +G+GT+ +G++ +K + + + G+R IDTA +Y NE+ I
Sbjct: 26 LRLNNGYDMPLVGIGTY---KVRGREVIK-----RVIDESFAVGFRSIDTAVVYRNEEDI 77
Query: 286 GAAVRAS----GIPREDIFIVTKL-PMDN--QRDVVKQLEKSLARLNMSYVDLYLIHNPV 444
G A++ + REDIFI +KL P DN + K +E SL L+ SY+DLYLIH P
Sbjct: 78 GLALKELLPKYNLKREDIFITSKLSPSDNGDPDKIRKSVEDSLKALDTSYLDLYLIHWPG 137
Query: 445 A 447
A
Sbjct: 138 A 138
>UniRef50_Q14LU6 Cluster: Putative aldo/keto reductase
oxidoreductase protein; n=1; Spiroplasma citri|Rep:
Putative aldo/keto reductase oxidoreductase protein -
Spiroplasma citri
Length = 138
Score = 72.5 bits (170), Expect = 7e-12
Identities = 41/113 (36%), Positives = 69/113 (61%), Gaps = 2/113 (1%)
Frame = +1
Query: 100 SKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNED 279
+K+ L +G IP +GLGT+ DE + + + AL+ GYR IDTA +Y NE+
Sbjct: 6 TKLKLFNGVEIPLIGLGTYKMTDEH--------EVYQAIITALQNGYRHIDTAQIYGNEE 57
Query: 280 QIGAAVRASGIPREDIFIVTKLPMDNQR--DVVKQLEKSLARLNMSYVDLYLI 432
IG A++ SG+PR++IF+ +K+ N + +++++ L RL+ Y+DL L+
Sbjct: 58 LIGKAIKDSGVPRKEIFLTSKIWNANHKYDAALQEIDNILKRLDTDYLDLCLV 110
>UniRef50_A6LZ55 Cluster: 2,5-didehydrogluconate reductase; n=1;
Clostridium beijerinckii NCIMB 8052|Rep:
2,5-didehydrogluconate reductase - Clostridium
beijerinckii NCIMB 8052
Length = 289
Score = 72.5 bits (170), Expect = 7e-12
Identities = 49/139 (35%), Positives = 73/139 (52%), Gaps = 2/139 (1%)
Frame = +1
Query: 103 KISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQ 282
+I +G IP +G G + K K D E V A++ GYR DTA +Y NE
Sbjct: 7 EIKAVNGIKIPQVGFGVY--------KLNKGEDFETAVGEAIKIGYRHFDTAKIYGNEKD 58
Query: 283 IGAAVRASGIPREDIFIVTKL-PMDNQRDVVKQ-LEKSLARLNMSYVDLYLIHNPVAFNP 456
+G A+ S IPRE+ FI +K+ D+ + K+ E++ +LN+ Y+D+YLIH ++
Sbjct: 59 LGLAIEKSQIPREEFFITSKVWNTDHGYEATKKAFEQTCKKLNVEYLDMYLIHFASSY-- 116
Query: 457 GFKGFDIVDYLDTWKGMEE 513
YL+TW MEE
Sbjct: 117 ---------YLETWHAMEE 126
>UniRef50_Q4Q973 Cluster: Aldo/keto reductase, putative; n=3;
Leishmania|Rep: Aldo/keto reductase, putative -
Leishmania major
Length = 414
Score = 72.5 bits (170), Expect = 7e-12
Identities = 40/107 (37%), Positives = 63/107 (58%), Gaps = 3/107 (2%)
Frame = +1
Query: 130 IPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGAAVRASG 309
+P +G+GT+ E++ V+ AL+ GYRLIDTAA Y NE+ +G + +SG
Sbjct: 20 VPPIGIGTY---------ELRGDACVSAVRAALQMGYRLIDTAAAYRNEELVGEGISSSG 70
Query: 310 IPREDIFIVTKLPMDNQR--DVVKQ-LEKSLARLNMSYVDLYLIHNP 441
+PR D+FIV K+ M + + V+Q + S+ +L + Y D L+H P
Sbjct: 71 VPRADLFIVVKIAMKSMSSDEAVRQGILDSIRKLRIDYADCVLMHWP 117
>UniRef50_Q6CEJ0 Cluster: Yarrowia lipolytica chromosome B of strain
CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome B of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 302
Score = 72.5 bits (170), Expect = 7e-12
Identities = 43/115 (37%), Positives = 64/115 (55%), Gaps = 2/115 (1%)
Frame = +1
Query: 103 KISLNDGNSIPALGLGTFLGFDEK-GQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNED 279
K+ L++G IPA+G G+ + G+KE + + V A+ AG+ IDTA Y E
Sbjct: 5 KVKLSNGLEIPAIGFGSGTKWKRPPGEKEER--ELIDAVVSAINAGHLHIDTAEFYGTEK 62
Query: 280 QIGAAVRASGIPREDIFIVTKLPMD-NQRDVVKQLEKSLARLNMSYVDLYLIHNP 441
QIG A++ SG+PR+DIF+ +K D ++ + L L Y DL+LIH P
Sbjct: 63 QIGEAIKESGVPRKDIFLTSKTLFGLLADDPIESISNQLKTLQTDYFDLFLIHVP 117
>UniRef50_A6WDZ5 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:
Aldo/keto reductase - Kineococcus radiotolerans SRS30216
Length = 343
Score = 72.1 bits (169), Expect = 9e-12
Identities = 41/115 (35%), Positives = 64/115 (55%), Gaps = 5/115 (4%)
Frame = +1
Query: 112 LNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGA 291
L G ++PA+G+GTF G P + V A+ AGYRL+D AA+Y NE Q+G
Sbjct: 18 LRGGATVPAIGIGTF------GSDRYSPAEVAAAVAGAVAAGYRLVDCAAVYGNEAQVGE 71
Query: 292 AVR---ASGIPREDIFIVTKLPMDNQ--RDVVKQLEKSLARLNMSYVDLYLIHNP 441
A+ A G+ R+++F+V+K+ D D V + +SL L + ++D +H P
Sbjct: 72 ALAGAVAGGVDRDELFVVSKVWNDAHAPADAVASVHRSLRDLRLDHLDAVFVHWP 126
>UniRef50_A5KSS3 Cluster: Aldehyde reductase; n=1; candidate
division TM7 genomosp. GTL1|Rep: Aldehyde reductase -
candidate division TM7 genomosp. GTL1
Length = 299
Score = 72.1 bits (169), Expect = 9e-12
Identities = 53/157 (33%), Positives = 81/157 (51%), Gaps = 16/157 (10%)
Frame = +1
Query: 106 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 285
++L + ++P LG GT+ E+ G + V+ A++AGYR ID A +Y NE ++
Sbjct: 4 LTLRNKQTLPLLGYGTW---------ELPTGTTADLVETAIKAGYRHIDCAMIYGNEKEV 54
Query: 286 GAAVRAS----GIPREDIFIVTKL-PMDN-QRDVVKQLEKSLARLNMSYVDLYLIHNPVA 447
G +R + + RED+F+ +KL D+ Q DV K+L L + Y+DLYLIH VA
Sbjct: 55 GEGIRRTIDQGVVKREDLFVTSKLWNTDHAQVDVGVACRKTLNDLGLDYLDLYLIHWGVA 114
Query: 448 F----------NPGFKGFDIVDYLDTWKGMEEAKNLG 528
F + G F + +TW+ MEE G
Sbjct: 115 FEHGDNLEPLDDDGVAKFSFISMKETWQAMEELVEQG 151
>UniRef50_A3VRL4 Cluster: Putative uncharacterized protein; n=1;
Parvularcula bermudensis HTCC2503|Rep: Putative
uncharacterized protein - Parvularcula bermudensis
HTCC2503
Length = 278
Score = 72.1 bits (169), Expect = 9e-12
Identities = 40/107 (37%), Positives = 66/107 (61%), Gaps = 2/107 (1%)
Frame = +1
Query: 130 IPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGAAVRASG 309
IP LG GT+ +++ D+ + A+E GYR ID AA+Y NE ++G ++ SG
Sbjct: 11 IPRLGFGTW---------QLEGEDARTSTRTAIETGYRHIDGAAIYKNEKKVGEGIKDSG 61
Query: 310 IPREDIFIVTKL-PMDNQRDVVKQ-LEKSLARLNMSYVDLYLIHNPV 444
IPR+++F+ TK+ D Q+ + +++SL RL + YV+L L+H P+
Sbjct: 62 IPRDELFVTTKIWNEDIQKGRHSEAVDESLDRLGLDYVNLILLHWPI 108
>UniRef50_Q2LZ66 Cluster: GA19341-PA; n=2; Endopterygota|Rep:
GA19341-PA - Drosophila pseudoobscura (Fruit fly)
Length = 315
Score = 72.1 bits (169), Expect = 9e-12
Identities = 54/156 (34%), Positives = 86/156 (55%), Gaps = 17/156 (10%)
Frame = +1
Query: 112 LNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGA 291
L+ G ++P +GLGT+ + EV + VK A++ GYR D A +Y NE +G
Sbjct: 8 LSSGRNMPMVGLGTW-----RSPPEVVA----QAVKDAIDIGYRHFDCAHIYGNELHVGV 58
Query: 292 AVRAS---G-IPREDIFIVTKL-PMDNQRDVVKQL-EKSLARLNMSYVDLYLIHNPVAF- 450
A+R G + R+++FI +KL ++ ++V+ E SL L + Y+DLYL+H P+A+
Sbjct: 59 AIREKIQEGLVTRDELFITSKLWNTFHKPELVRAACETSLRNLGIDYLDLYLMHWPMAYK 118
Query: 451 ----------NPGFKGFDIVDYLDTWKGMEEAKNLG 528
+ G F+ +DYLDTWK ME+ + G
Sbjct: 119 SGDNLYPTCPDTGKAVFEDIDYLDTWKAMEDLVDSG 154
>UniRef50_A2EYY6 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=9; Trichomonas vaginalis G3|Rep:
Oxidoreductase, aldo/keto reductase family protein -
Trichomonas vaginalis G3
Length = 308
Score = 72.1 bits (169), Expect = 9e-12
Identities = 58/155 (37%), Positives = 81/155 (52%), Gaps = 20/155 (12%)
Frame = +1
Query: 124 NSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWAL-EAGYRLIDTAALYLNEDQIGAAVR 300
N IP +GLGT+ K + D + +A+ EAGY ID A Y NED +G A++
Sbjct: 2 NRIPTIGLGTW--------KSPRSEDLVNAITYAIKEAGYVHIDCALCYENEDIVGQALQ 53
Query: 301 A---SGIPREDIFIVTKLPMDNQR-DVVKQL-EKSLARLNMSYVDLYLIHNPVAF-NPGF 462
SGI RE+I+I +KL + R ++V++ K+L L + Y+DLYL+H P AF N G
Sbjct: 54 QCWDSGIKRENIWITSKLWNTHHRLEIVEEACRKTLKDLRLDYLDLYLMHYPFAFQNTGI 113
Query: 463 KGF-------------DIVDYLDTWKGMEEAKNLG 528
G D V +DTWK ME+ G
Sbjct: 114 GGSLNPLDEKGNTIFDDGVSLIDTWKAMEKLVEKG 148
>UniRef50_Q8ZH36 Cluster: 2,5-diketo-D-gluconic acid reductase B;
n=91; Proteobacteria|Rep: 2,5-diketo-D-gluconic acid
reductase B - Yersinia pestis
Length = 267
Score = 72.1 bits (169), Expect = 9e-12
Identities = 47/107 (43%), Positives = 65/107 (60%), Gaps = 2/107 (1%)
Frame = +1
Query: 127 SIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGAAVRAS 306
SIP GLGTF + Q ++ DS V AL GYR IDTA +Y NE +G A++ S
Sbjct: 2 SIPVFGLGTF-----RLQDQIVI-DS---VSQALTLGYRAIDTAQIYENEAPVGQAIQES 52
Query: 307 GIPREDIFIVTKLPMDN-QRD-VVKQLEKSLARLNMSYVDLYLIHNP 441
GI R+++FI TK+ + N +D ++ L +S+ +L YVDL LIH P
Sbjct: 53 GINRDELFITTKIWIANLSKDKLIPSLRESIQKLKTDYVDLTLIHWP 99
>UniRef50_Q6U5V3 Cluster: Putative uncharacterized protein; n=1;
Klebsiella pneumoniae|Rep: Putative uncharacterized
protein - Klebsiella pneumoniae
Length = 279
Score = 71.7 bits (168), Expect = 1e-11
Identities = 44/116 (37%), Positives = 67/116 (57%), Gaps = 3/116 (2%)
Frame = +1
Query: 106 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 285
I LNDG +P G G +L D + D + ++ AL+AG+R DTA Y NED +
Sbjct: 6 ILLNDGYYMPRPGCGLWL-IDNR--------DVDSLIRQALKAGFRHFDTAQAYFNEDGV 56
Query: 286 GAAVRASGIPREDIFIVTKL---PMDNQRDVVKQLEKSLARLNMSYVDLYLIHNPV 444
G A+R + +PRE +FI +K+ M R +V ++L RL + Y++L+LIH P+
Sbjct: 57 GRALRYTEVPREQLFITSKIRGRDMGYARTLV-SFNETLERLGVEYLELFLIHWPI 111
>UniRef50_Q0IBY6 Cluster: Alcohol dehydrogenase; n=2;
Chroococcales|Rep: Alcohol dehydrogenase - Synechococcus
sp. (strain CC9311)
Length = 336
Score = 71.7 bits (168), Expect = 1e-11
Identities = 56/169 (33%), Positives = 90/169 (53%), Gaps = 15/169 (8%)
Frame = +1
Query: 109 SLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIG 288
SL++G+ +P LGLGT G+ E + K V+ A++ GYR ID A++Y NE+++G
Sbjct: 23 SLSNGDRMPLLGLGT-------GKSESR--QVYKSVREAIKIGYRHIDCASIYGNEEEVG 73
Query: 289 AAVRAS----GIPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIHNPVAF 450
A+R + I R +++I +KL + V L +SL L + Y++LYLIH PV
Sbjct: 74 DAIRDAIQNHEITRSELWITSKLWSNCHGKNHVEAALSQSLQNLGVDYLNLYLIHWPVGI 133
Query: 451 NPGFKGFDIVDYL---------DTWKGMEEAKNLGPS*IYRHI*LQHHT 570
P + VD L +TW+ ME ++ G + +HI + + T
Sbjct: 134 RPEKTFAESVDDLLTPEESPISETWEAMESTRDKG---LTKHIGVSNFT 179
>UniRef50_A6NPD6 Cluster: Putative uncharacterized protein; n=3;
Bacteria|Rep: Putative uncharacterized protein -
Bacteroides capillosus ATCC 29799
Length = 287
Score = 71.7 bits (168), Expect = 1e-11
Identities = 53/148 (35%), Positives = 75/148 (50%), Gaps = 4/148 (2%)
Frame = +1
Query: 97 ASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPV-KWALEAGYRLIDTAALYLN 273
A++ L++G SIPA+G GT+ K GD + V A+ GYR DTA+ Y
Sbjct: 5 ATQFVLSNGLSIPAVGFGTY-----------KTGDGDSAVLSNAIAQGYRHFDTASFYGT 53
Query: 274 EDQIGAAVRASGIPREDIFIVTKL-PMDNQRD-VVKQLEKSLARLNMSYVDLYLIHNPVA 447
E +G AV S IPRED F+ +KL + D ++ + +L RL Y+DLYLIH P
Sbjct: 54 ETALGQAVAESDIPREDFFLTSKLWKTEMGYDAALRAFDATLERLGTDYLDLYLIHWP-- 111
Query: 448 FNPGFKGFDIVDY-LDTWKGMEEAKNLG 528
P + D +TW+ +E G
Sbjct: 112 -RPDLELEDWAKLDRETWRALERLYESG 138
>UniRef50_A5PDA8 Cluster: Putative oxidoreductase protein; n=1;
Erythrobacter sp. SD-21|Rep: Putative oxidoreductase
protein - Erythrobacter sp. SD-21
Length = 272
Score = 71.7 bits (168), Expect = 1e-11
Identities = 51/143 (35%), Positives = 74/143 (51%), Gaps = 2/143 (1%)
Frame = +1
Query: 106 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 285
++LNDG IP LG GT+ +++ D+ + V A++ GY LIDTAA+Y NE +
Sbjct: 7 LNLNDGRQIPQLGFGTW---------QMEEEDAPQAVSTAIDVGYWLIDTAAIYGNEKGV 57
Query: 286 GAAVRASGIPREDIFIVTKLPMDNQ--RDVVKQLEKSLARLNMSYVDLYLIHNPVAFNPG 459
G V DIF+ TK+ D+Q ++ EK L RL +VD+ LIH P
Sbjct: 58 GKGVG----EWSDIFLQTKIWNDSQGYDRTLRAAEKCLERLGREHVDMLLIHWPCPEKDQ 113
Query: 460 FKGFDIVDYLDTWKGMEEAKNLG 528
F +DTWK + E ++ G
Sbjct: 114 F--------VDTWKALIELRDAG 128
>UniRef50_Q5KKZ8 Cluster: Aldo-keto reductase, putative; n=2;
Filobasidiella neoformans|Rep: Aldo-keto reductase,
putative - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 293
Score = 71.7 bits (168), Expect = 1e-11
Identities = 46/131 (35%), Positives = 70/131 (53%), Gaps = 9/131 (6%)
Frame = +1
Query: 100 SKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNED 279
S I L GN IP LG G + + + + E VK A++ GYR +DTA Y NE+
Sbjct: 7 STIKLASGNLIPRLGFGVY---------QARSKECEDAVKKAIDTGYRHVDTAQAYHNEE 57
Query: 280 QIGAAVRASGIPREDIFIVTK-LP---MDNQRDVVKQLEKSLARL-----NMSYVDLYLI 432
+G A+R SG+PR +F+ +K +P + + +V+ + KSL ++ + Y+DL LI
Sbjct: 58 NVGRAIRNSGVPRPSVFLTSKYMPSHTVYSPTEVLDVVRKSLKKVDRCGDDKPYIDLMLI 117
Query: 433 HNPVAFNPGFK 465
H P G K
Sbjct: 118 HAPWGGEEGRK 128
>UniRef50_UPI00015B4912 Cluster: PREDICTED: similar to aldo-keto
reductase; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to aldo-keto reductase - Nasonia vitripennis
Length = 353
Score = 71.3 bits (167), Expect = 2e-11
Identities = 48/117 (41%), Positives = 68/117 (58%), Gaps = 5/117 (4%)
Frame = +1
Query: 112 LNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGA 291
L+ G++ P +GLGT G +E + V G ALE G IDT+ +Y NE+ IG
Sbjct: 33 LSSGHNFPIVGLGTH-GLNEDVLETVLTG--------ALEKGIGHIDTSFVYKNEETIGK 83
Query: 292 AVR---ASGIPREDIFIVTKLPM-DNQRDVV-KQLEKSLARLNMSYVDLYLIHNPVA 447
++ A G REDIF+ +KLP DN + V K ++ SL +L + Y+D+YLIH P A
Sbjct: 84 VLKDWFAKGGKREDIFVTSKLPYYDNHPESVEKYIKLSLEKLGLQYLDMYLIHAPFA 140
>UniRef50_Q4P1G1 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 320
Score = 71.3 bits (167), Expect = 2e-11
Identities = 37/114 (32%), Positives = 63/114 (55%), Gaps = 4/114 (3%)
Frame = +1
Query: 199 DSEKPVKWALEAGYRLIDTAALYLNEDQIGAAVRA----SGIPREDIFIVTKLPMDNQRD 366
D+ K V AL++G+R ID A +Y NE +GA + + SG+ R DI+++TK+ + +D
Sbjct: 29 DAAKQVTMALDSGFRFIDGAEVYANEASMGAGIESFLASSGLKRNDIYVLTKVGKEGMKD 88
Query: 367 VVKQLEKSLARLNMSYVDLYLIHNPVAFNPGFKGFDIVDYLDTWKGMEEAKNLG 528
+ ++ L +L + +D YL+H P G + +D WK +E+ K G
Sbjct: 89 LQSAIKVELQKLKVDQLDSYLLHLPPRGQDG-----LPSNVDAWKELEKIKQAG 137
>UniRef50_Q979I4 Cluster: Aldo / keto reductase; n=3; Archaea|Rep:
Aldo / keto reductase - Thermoplasma volcanium
Length = 288
Score = 71.3 bits (167), Expect = 2e-11
Identities = 46/116 (39%), Positives = 71/116 (61%), Gaps = 7/116 (6%)
Frame = +1
Query: 115 NDGNSIPALGLGTFL--GFDEKGQKEVKPGDSEKPV---KWALEAGYRLIDTAALYLNED 279
N G + ++G+GT+ G+ + VK D+EK + + A++AG LIDTA +Y +ED
Sbjct: 15 NTGVKVSSVGIGTYYDPGWMALSRFNVKR-DAEKKIQAIRTAIDAGVTLIDTAEIYGSED 73
Query: 280 QIGAAVRASGIPREDIFIVTKLPMDNQR--DVVKQLEKSLARLNMSYVDLYLIHNP 441
+ A+ G RE++FI TK+ +++ R V+K + SL+RLN YVDLY IH P
Sbjct: 74 LVAKAIE--GHNREELFIATKVWINHLRYDKVIKACKASLSRLNTKYVDLYQIHFP 127
>UniRef50_Q5FT75 Cluster: Putative 2,5-diketo-D-gluconic acid
reductase; n=1; Gluconobacter oxydans|Rep: Putative
2,5-diketo-D-gluconic acid reductase - Gluconobacter
oxydans (Gluconobacter suboxydans)
Length = 279
Score = 70.9 bits (166), Expect = 2e-11
Identities = 50/143 (34%), Positives = 76/143 (53%), Gaps = 2/143 (1%)
Frame = +1
Query: 106 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 285
IS +DG+++P +GLG + E P ++ + VK A++ GYR +DTA LY NE+ +
Sbjct: 14 ISFHDGHTMPQIGLGVW---------ETPPDETAEVVKEAVKLGYRSVDTARLYKNEEGV 64
Query: 286 GAAVRASGIPREDIFIVTKLPMDNQ--RDVVKQLEKSLARLNMSYVDLYLIHNPVAFNPG 459
G + +IF+ TKL D Q ++ E+S L +DLYLIH P+ P
Sbjct: 65 GKGLE----DHPEIFLTTKLWNDEQGYDSTLRAYEESARLLRRPVLDLYLIHWPM---PA 117
Query: 460 FKGFDIVDYLDTWKGMEEAKNLG 528
+G Y++TWK + E K G
Sbjct: 118 -QG----QYVETWKALVELKKSG 135
>UniRef50_Q68A33 Cluster: Aldo-keto reductase 1a; n=1; Ciona
intestinalis|Rep: Aldo-keto reductase 1a - Ciona
intestinalis (Transparent sea squirt)
Length = 584
Score = 70.9 bits (166), Expect = 2e-11
Identities = 44/124 (35%), Positives = 70/124 (56%), Gaps = 13/124 (10%)
Frame = +1
Query: 106 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNED-- 279
+ LN G +P +GLGT F + + + VK AL+ GYR++DTA +Y ED
Sbjct: 260 VKLNSGYMMPPIGLGTARLFSK----------TYETVKTALKLGYRMLDTAQIYTGEDKI 309
Query: 280 ---------QIGAAVRASGIPREDIFIVTKLPMDN--QRDVVKQLEKSLARLNMSYVDLY 426
+IG A+ S +PR ++FIVTKL ++ + + + ++E+SL +L Y+DL
Sbjct: 310 NNFKVSSEEEIGRAIADSDVPRSELFIVTKLAPESMEKENAIAKVEESLKKLRTDYIDLL 369
Query: 427 LIHN 438
LIH+
Sbjct: 370 LIHD 373
>UniRef50_P23901 Cluster: Aldose reductase; n=9; Poaceae|Rep: Aldose
reductase - Hordeum vulgare (Barley)
Length = 320
Score = 70.9 bits (166), Expect = 2e-11
Identities = 48/136 (35%), Positives = 73/136 (53%), Gaps = 6/136 (4%)
Frame = +1
Query: 70 SEATTGGGKASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWAL-EAGYRL 246
++AT G G+ L G+++PA+GLGT+ D+ V+ A+ EAGYR
Sbjct: 4 AKATMGQGEQDHFVLKSGHAMPAVGLGTWRA----------GSDTAHSVRTAITEAGYRH 53
Query: 247 IDTAALYLNEDQIGAAVRA---SGIPREDIFIVTKLPMDN--QRDVVKQLEKSLARLNMS 411
+DTAA Y E ++G ++A +GI R+D+F+ +K+ N V LE +L L +
Sbjct: 54 VDTAAEYGVEKEVGKGLKAAMEAGIDRKDLFVTSKIWCTNLAPERVRPALENTLKDLQLD 113
Query: 412 YVDLYLIHNPVAFNPG 459
Y+DLY IH P G
Sbjct: 114 YIDLYHIHWPFRLKDG 129
>UniRef50_UPI00006CCCD7 Cluster: oxidoreductase, aldo/keto reductase
family protein; n=1; Tetrahymena thermophila SB210|Rep:
oxidoreductase, aldo/keto reductase family protein -
Tetrahymena thermophila SB210
Length = 323
Score = 70.5 bits (165), Expect = 3e-11
Identities = 55/152 (36%), Positives = 80/152 (52%), Gaps = 11/152 (7%)
Frame = +1
Query: 106 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 285
+ LN+G +P LGLGT +D + V+ + + AL+ GYR DTA Y NE +I
Sbjct: 15 VQLNNGYKMPLLGLGT-QPYDIVTRVTVE--EMTTLLSNALDFGYRNFDTAKQYRNEVEI 71
Query: 286 GAA----VRASGIPREDIFIVTKL-PMDNQRDVVKQLEKSLARLNMSYVDLYLIH---NP 441
G A + RED+FI TKL P ++ + + ++ SL +L SY+DLYLI P
Sbjct: 72 GQAFQNIFQQGKYKREDVFITTKLFPFKIEKKIKEVVQNSLDQLQTSYIDLYLIQWSFTP 131
Query: 442 VAFNPGFKGFDIVDYL---DTWKGMEEAKNLG 528
V N F G V++ + W+ +EE LG
Sbjct: 132 VLTN--FDGSVAVNHRPIHEVWRELEECVELG 161
>UniRef50_Q11DV1 Cluster: Aldo/keto reductase; n=10;
Alphaproteobacteria|Rep: Aldo/keto reductase -
Mesorhizobium sp. (strain BNC1)
Length = 274
Score = 70.5 bits (165), Expect = 3e-11
Identities = 41/109 (37%), Positives = 61/109 (55%), Gaps = 2/109 (1%)
Frame = +1
Query: 121 GNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGAAVR 300
G +IPALG G F + + E+ + ALEAG+R DTA +Y NE +G A+
Sbjct: 8 GATIPALGFGVF---------RMSDAEVERIIPAALEAGFRHFDTAQIYQNEAALGRALE 58
Query: 301 ASGIPREDIFIVTKLPMDNQR--DVVKQLEKSLARLNMSYVDLYLIHNP 441
+G RED+F+ TK+ +DN +++SL +L + VDL L+H P
Sbjct: 59 RAGARREDLFLTTKVWVDNYSADKFAASVDESLEKLKVDQVDLLLLHWP 107
>UniRef50_Q03XK0 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=3; Lactobacillales|Rep: Aldo/keto
reductase of diketogulonate reductase family -
Leuconostoc mesenteroides subsp. mesenteroides (strain
ATCC 8293 /NCDO 523)
Length = 292
Score = 70.5 bits (165), Expect = 3e-11
Identities = 52/146 (35%), Positives = 77/146 (52%), Gaps = 6/146 (4%)
Frame = +1
Query: 109 SLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIG 288
+L G +P LG G F EKG +++ V A++ GYRLIDTAA Y NE ++G
Sbjct: 5 TLASGIEMPLLGFGVFQ-VQEKGA-------AKQAVLDAIKTGYRLIDTAASYGNEREVG 56
Query: 289 AAVRAS---GI-PREDIFIVTKLPMD--NQRDVVKQLEKSLARLNMSYVDLYLIHNPVAF 450
A+ + GI RE++F+ +K+ + + + ++ SL RLN+ Y+DLYLIH P +
Sbjct: 57 EAILEAINQGIVKREELFVTSKMWVQDVSAQQATAAIQSSLQRLNLDYLDLYLIHQP--Y 114
Query: 451 NPGFKGFDIVDYLDTWKGMEEAKNLG 528
N D W+ ME A G
Sbjct: 115 N---------DVFGAWRAMESAYRSG 131
>UniRef50_A6QXT4 Cluster: Predicted protein; n=1; Ajellomyces
capsulatus NAm1|Rep: Predicted protein - Ajellomyces
capsulatus NAm1
Length = 315
Score = 70.5 bits (165), Expect = 3e-11
Identities = 39/97 (40%), Positives = 58/97 (59%), Gaps = 3/97 (3%)
Frame = +1
Query: 250 DTAALYLNEDQIGAAVRASGIPREDIFIVTKLPMDNQRDVVKQLEKSLARLNMSYVDLYL 429
DTA Y ED +G A+RASG+PR +VTKL D +SLA+L++ Y+D++L
Sbjct: 17 DTAPGYATEDLLGEAIRASGVPRSAFTVVTKLLQTQHHDPEASFRESLAKLDVGYIDIFL 76
Query: 430 IHNPVAFNPG--FKGFD-IVDYLDTWKGMEEAKNLGP 531
+H P A P ++G D +++T+K ME K +GP
Sbjct: 77 LHWPNASGPDGRWRGIDERPTFVETYKKME--KLVGP 111
>UniRef50_Q5V663 Cluster: Aldehyde reductase; n=6;
Halobacteriaceae|Rep: Aldehyde reductase - Haloarcula
marismortui (Halobacterium marismortui)
Length = 279
Score = 70.5 bits (165), Expect = 3e-11
Identities = 42/106 (39%), Positives = 61/106 (57%), Gaps = 2/106 (1%)
Frame = +1
Query: 124 NSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGAAVRA 303
+ +P LGLGT+ D + E V+ ALEAGYR IDTA Y NE +G + A
Sbjct: 15 SGMPMLGLGTWQNEDAEQCAE--------SVRTALEAGYRHIDTAQAYDNESAVGDGIAA 66
Query: 304 SGIPREDIFIVTKLPMDN--QRDVVKQLEKSLARLNMSYVDLYLIH 435
+ + R+DIF+ TK+ + N DV++ E+SL +L + VDL +H
Sbjct: 67 ADVDRDDIFLATKVWISNLSHDDVIETTEESLDKLGVDSVDLLYVH 112
>UniRef50_UPI000155CAC7 Cluster: PREDICTED: hypothetical protein;
n=1; Ornithorhynchus anatinus|Rep: PREDICTED:
hypothetical protein - Ornithorhynchus anatinus
Length = 419
Score = 70.1 bits (164), Expect = 3e-11
Identities = 59/153 (38%), Positives = 81/153 (52%), Gaps = 4/153 (2%)
Frame = +1
Query: 67 LSEATTGGG-KASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWAL-EAGY 240
++ AT G G + L +G +IP LGLGT G G S V +AL E G
Sbjct: 1 MASATLGKGLPVPTVPLANGLNIPILGLGT----SHVG------GYSHDAVIYALKECGI 50
Query: 241 RLIDTAALYLNEDQIGAAVRASGIPREDIFIVTKLPM-DNQRDVVKQ-LEKSLARLNMSY 414
R IDTA Y E +G A++ SG+ RE+++I TKL + D + KQ +S RL + Y
Sbjct: 51 RHIDTAKRYGCELLLGKAIQESGVKREELWITTKLWLTDYGYESAKQSCLESCNRLGVEY 110
Query: 415 VDLYLIHNPVAFNPGFKGFDIVDYLDTWKGMEE 513
+DL+LIH P A PG + +TW+ MEE
Sbjct: 111 LDLFLIHWPDAQLPGKSSREA--RAETWRAMEE 141
>UniRef50_Q11BF8 Cluster: Aldo/keto reductase; n=12; Bacteria|Rep:
Aldo/keto reductase - Mesorhizobium sp. (strain BNC1)
Length = 308
Score = 70.1 bits (164), Expect = 3e-11
Identities = 38/110 (34%), Positives = 62/110 (56%), Gaps = 2/110 (1%)
Frame = +1
Query: 121 GNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGAAVR 300
G +P +GLG F + P ++ V+ AL GYR IDTAA Y NE ++G +R
Sbjct: 26 GVEMPMIGLGVF---------QTPPDETTAAVEEALRLGYRHIDTAAAYGNEREVGEGIR 76
Query: 301 ASGIPREDIFIVTKLPMDN--QRDVVKQLEKSLARLNMSYVDLYLIHNPV 444
+GI R+++FI TK+ + + + + +KS +L + +DL L+H P+
Sbjct: 77 RAGIARDEVFIETKIWISDYGYDETLHAFDKSAGKLGVDQIDLLLLHQPL 126
>UniRef50_Q41399 Cluster: Chalcone reductase; n=4;
eudicotyledons|Rep: Chalcone reductase - Sesbania
rostrata
Length = 322
Score = 70.1 bits (164), Expect = 3e-11
Identities = 56/160 (35%), Positives = 84/160 (52%), Gaps = 15/160 (9%)
Frame = +1
Query: 94 KASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN 273
K ++ LN G+ +P +G+GT + + + +V A++ GYR D+A++Y
Sbjct: 5 KIPEVLLNSGHKMPVIGMGTSV--ESRPSNDVLASIFVD----AIQVGYRHFDSASVYGT 58
Query: 274 EDQIGAAVRAS---GI--PREDIFIVTK-LPMDNQRD-VVKQLEKSLARLNMSYVDLYLI 432
E+ IG AV + G+ R+++FI +K D D +V L+ +L +L M YVDLYLI
Sbjct: 59 EEAIGMAVSKAIEQGLIKSRDEVFITSKPWNTDAHHDLIVPALKTTLKKLGMEYVDLYLI 118
Query: 433 HNPVAF-----NPG-FKGFDIV--DYLDTWKGMEEAKNLG 528
H PV NP F D++ D TWK MEE LG
Sbjct: 119 HWPVRLRHDLENPVIFSKEDLLPFDIEGTWKAMEECYRLG 158
>UniRef50_A2FPE2 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=3; Trichomonas vaginalis G3|Rep:
Oxidoreductase, aldo/keto reductase family protein -
Trichomonas vaginalis G3
Length = 309
Score = 70.1 bits (164), Expect = 3e-11
Identities = 55/152 (36%), Positives = 80/152 (52%), Gaps = 19/152 (12%)
Frame = +1
Query: 130 IPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALE-AGYRLIDTAALYLNEDQIGAAVR-- 300
IP++GLGTFL D P + V A+E +GYR +D AA Y N++ IG A+
Sbjct: 4 IPSIGLGTFLAED--------PAALKAAVHSAIEDSGYRHVDCAAYYKNQEIIGEALSEI 55
Query: 301 -ASG-IPREDIFIVTKLPMDNQRD--VVKQLEKSLARLNMSYVDLYLIHNPVAF------ 450
A G + RE+++I +K+ R +VK ++K+L L + Y+DL L+H AF
Sbjct: 56 FAKGQVKREEVWITSKVWNTKHRPDLLVKDVKKTLKELKLEYLDLVLVHWACAFQSREDD 115
Query: 451 ------NPGFKGFDIVDYLDTWKGMEEAKNLG 528
G + +D L+TWK MEE NLG
Sbjct: 116 EYLPRDETGKIITENIDILETWKAMEECYNLG 147
>UniRef50_Q4WI64 Cluster: Aldehyde reductase, putative; n=22;
Pezizomycotina|Rep: Aldehyde reductase, putative -
Aspergillus fumigatus (Sartorya fumigata)
Length = 295
Score = 70.1 bits (164), Expect = 3e-11
Identities = 46/149 (30%), Positives = 72/149 (48%), Gaps = 6/149 (4%)
Frame = +1
Query: 100 SKISLNDGNSIPALGLGTFLGFDEKG---QKEVKPGD-SEKPVKWALEAGYRLIDTAALY 267
S + G IP +G G+ + + + +P + +EK ALE GYR ID+A Y
Sbjct: 8 STYKMVSGYEIPVVGFGSSFRIETPCLTCRWQCRPPEITEKATLKALETGYRHIDSAKYY 67
Query: 268 LNEDQIGAAVRASGIPREDIFIVTKLPMDNQ--RDVVKQLEKSLARLNMSYVDLYLIHNP 441
NE + A++ SGI R IF TK+P + + +E+S+A ++ Y+DL L+H P
Sbjct: 68 ANEKECAVAMKKSGIDRSKIFFTTKVPASSMSYEKAKEAIEQSVAATDLGYIDLILLHAP 127
Query: 442 VAFNPGFKGFDIVDYLDTWKGMEEAKNLG 528
G L W+ + EA+ G
Sbjct: 128 YGGKEG--------RLGAWRALVEAQKAG 148
>UniRef50_A7TLC4 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 313
Score = 70.1 bits (164), Expect = 3e-11
Identities = 49/139 (35%), Positives = 70/139 (50%), Gaps = 6/139 (4%)
Frame = +1
Query: 112 LNDGNSIPAL---GLGTFLGFDEKGQKEVKPGDSEKPVKWALEA-GYRLIDTAALYLNED 279
LN+GN IP++ G GT F G + + + +K+AL G ID A Y
Sbjct: 10 LNNGNQIPSISIIGTGT-RWFKRPGSEHTFSDELVEQIKYALSLPGIIHIDAAECYGTYP 68
Query: 280 QIGAAVRASGIPREDIFIVTKLPMDNQ--RDVVKQLEKSLARLNMSYVDLYLIHNPVAFN 453
++ A++ S PR +IFI K + D ++ L L L + YVDLYLIH+P F+
Sbjct: 69 ELAKALKESSKPRSEIFITDKYSTQTKFTNDPIEGLNTGLKTLGLDYVDLYLIHSPF-FD 127
Query: 454 PGFKGFDIVDYLDTWKGME 510
P FKG ++ WK ME
Sbjct: 128 PEFKGSLTLE--KVWKDME 144
>UniRef50_Q97UV9 Cluster: Oxidoreductase; n=1; Sulfolobus
solfataricus|Rep: Oxidoreductase - Sulfolobus
solfataricus
Length = 304
Score = 70.1 bits (164), Expect = 3e-11
Identities = 42/88 (47%), Positives = 56/88 (63%), Gaps = 5/88 (5%)
Frame = +1
Query: 208 KPVKWALEAGYRLIDTAALY---LNEDQIGAAVRASGIPREDIFIVTKLPMDNQR--DVV 372
K ++ A+E G IDTA Y L+E IG A+ S RED+FI+TK+ +D+ R DV+
Sbjct: 36 KAIQRAIELGINAIDTAESYGNGLSETIIGRAI--SKFKREDLFIITKVSIDHLRYDDVL 93
Query: 373 KQLEKSLARLNMSYVDLYLIHNPVAFNP 456
K E SL RLN SY+DLYL+H P + P
Sbjct: 94 KASEGSLKRLNTSYIDLYLVHWPNHYVP 121
>UniRef50_UPI00006CA3CB Cluster: oxidoreductase, aldo/keto reductase
family protein; n=3; Tetrahymena thermophila SB210|Rep:
oxidoreductase, aldo/keto reductase family protein -
Tetrahymena thermophila SB210
Length = 299
Score = 69.7 bits (163), Expect = 5e-11
Identities = 50/146 (34%), Positives = 78/146 (53%), Gaps = 5/146 (3%)
Frame = +1
Query: 106 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 285
I+L++G +PA GLG+ + +EV ++ AL+ GYR IDTA +Y NE I
Sbjct: 10 ITLSNGQKMPAFGLGSSR---VQSVEEVT-----NLIRKALDVGYRHIDTAQMYENEQFI 61
Query: 286 GAAVRA----SGIPREDIFIVTKLPMDNQRDVVKQLEKSLARLNMSYVDLYLIHNPVAF- 450
GAA++ REDIF+VTK ++ +++ L +L + YVDL LIH P+A
Sbjct: 62 GAALKTIFGEGKYKREDIFLVTKQASIKGVSCLEIMKEQLQKLQVDYVDLLLIHVPLAAP 121
Query: 451 NPGFKGFDIVDYLDTWKGMEEAKNLG 528
+ ++ ++ W EE +LG
Sbjct: 122 SDDYQQWNHKPVHQIWAEFEEIHSLG 147
>UniRef50_Q1RFP0 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=21; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase
A - Escherichia coli (strain UTI89 / UPEC)
Length = 294
Score = 69.7 bits (163), Expect = 5e-11
Identities = 56/160 (35%), Positives = 81/160 (50%), Gaps = 13/160 (8%)
Frame = +1
Query: 112 LNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGA 291
L++ +P +G G F D K+V ++ V A+ GYRLIDTAA+Y NED +G
Sbjct: 11 LSNNLKMPMMGFGVFQVTD----KDV----CKQSVLNAIRTGYRLIDTAAVYGNEDAVGE 62
Query: 292 AVR---ASGI-PREDIFIVTKL---PMDNQRDVVKQLEKSLARLNMSYVDLYLIHNPVAF 450
AVR + G+ RE++FI +KL M NQ +E SL + + Y DLYL+H +
Sbjct: 63 AVREAISEGLCTREELFITSKLWVQDMLNQDIAAAGIEASLKKSGLEYFDLYLLHQAMR- 121
Query: 451 NPGFKGFDIVDYLDTWKGMEEA------KNLGPS*IYRHI 552
DY W+ +E+A K +G S Y H+
Sbjct: 122 ----------DYFSAWRALEDAYEEGKLKAIGVSNFYPHV 151
>UniRef50_Q6C2L0 Cluster: Yarrowia lipolytica chromosome F of strain
CLIB122 of Yarrowia lipolytica; n=3; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome F of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 324
Score = 69.7 bits (163), Expect = 5e-11
Identities = 45/116 (38%), Positives = 67/116 (57%), Gaps = 4/116 (3%)
Frame = +1
Query: 112 LNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGA 291
LNDG+SIPALGLGT G+ E+ V A++ GYR IDTA +Y +E +G
Sbjct: 9 LNDGHSIPALGLGT-----------ASDGNVEEVVYAAIKNGYRHIDTAFIYGSEVDVGK 57
Query: 292 AVRASG----IPREDIFIVTKLPMDNQRDVVKQLEKSLARLNMSYVDLYLIHNPVA 447
++ + + RE++F+ TK+ V + L+ SL L++ YVDL L+H PV+
Sbjct: 58 GIKRAIDEELVKRENLFVTTKVWPTFYNRVSESLDISLKDLSLDYVDLLLVHWPVS 113
>UniRef50_P26690 Cluster: NAD(P)H-dependent 6'-deoxychalcone
synthase; n=3; Papilionoideae|Rep: NAD(P)H-dependent
6'-deoxychalcone synthase - Glycine max (Soybean)
Length = 315
Score = 69.7 bits (163), Expect = 5e-11
Identities = 44/123 (35%), Positives = 68/123 (55%), Gaps = 13/123 (10%)
Frame = +1
Query: 199 DSEKPVKWALEAGYRLIDTAALYLNEDQIGAAVRAS---G-IPREDIFIVTKLPMDNQRD 366
D+++ + A++ GYR DTAA Y +E +G A++ + G + R+D+F+ +KL +
Sbjct: 37 DTKEAIIEAVKQGYRHFDTAAAYGSEQALGEALKEAIHLGLVSRQDLFVTSKLWVTENHP 96
Query: 367 --VVKQLEKSLARLNMSYVDLYLIHNPVAFNPGFKGFDI-------VDYLDTWKGMEEAK 519
V+ L KSL L + Y+DLYLIH P++ PG F I D W+ MEE +
Sbjct: 97 HLVLPALRKSLKTLQLEYLDLYLIHWPLSSQPGKFSFPIEVEDLLPFDVKGVWESMEECQ 156
Query: 520 NLG 528
LG
Sbjct: 157 KLG 159
>UniRef50_A7PNI3 Cluster: Chromosome chr1 scaffold_22, whole genome
shotgun sequence; n=2; Vitis vinifera|Rep: Chromosome
chr1 scaffold_22, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 360
Score = 69.3 bits (162), Expect = 6e-11
Identities = 59/165 (35%), Positives = 82/165 (49%), Gaps = 17/165 (10%)
Frame = +1
Query: 85 GGGKASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGD-SEKPVKWALEAGYRLIDTAA 261
GG + LN IPA+GLGT+ + G GD + VK AL GYR ID A
Sbjct: 5 GGAPGTYFLLNTKAKIPAIGLGTW----QSG------GDLCVEAVKRALSEGYRQIDCAH 54
Query: 262 LYLNEDQIGAAVRAS---GIPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLY 426
LY NE ++G A+ + + RED+F+ +KL M++ + + SL L ++Y+DLY
Sbjct: 55 LYGNEVEVGEALAEAFNGSLKREDVFLTSKLYCTMNSLNKIENSVRVSLKNLGVTYLDLY 114
Query: 427 LIHNP--VAFN-----PGFKGFDIVDYLD----TWKGMEEAKNLG 528
L+H P AF P G D +L+ WK ME LG
Sbjct: 115 LMHWPDITAFGDATDPPSNSGNDHRQFLNRLKKAWKAMEGLIELG 159
>UniRef50_Q4WUF7 Cluster: Aldo-keto reductase, putative; n=3;
Pezizomycotina|Rep: Aldo-keto reductase, putative -
Aspergillus fumigatus (Sartorya fumigata)
Length = 283
Score = 69.3 bits (162), Expect = 6e-11
Identities = 37/85 (43%), Positives = 54/85 (63%), Gaps = 4/85 (4%)
Frame = +1
Query: 223 ALEAGYRLIDTAALYLNEDQIGAAVRASGIPREDIFIVTKL--PMDNQRDVVKQLEKSLA 396
ALEAGYR IDTA Y NE ++G A+R GIPR D+F+ TK+ P + ++L +S+
Sbjct: 42 ALEAGYRHIDTAQFYGNEKEVGEALRKCGIPRSDVFVTTKILSPAGSPEATYQKLLESVE 101
Query: 397 RL--NMSYVDLYLIHNPVAFNPGFK 465
++ YVDL+LIH+ + + G K
Sbjct: 102 KIGGRDGYVDLFLIHSSSSGSAGRK 126
>UniRef50_Q11B35 Cluster: Aldo/keto reductase; n=1; Mesorhizobium
sp. BNC1|Rep: Aldo/keto reductase - Mesorhizobium sp.
(strain BNC1)
Length = 253
Score = 68.9 bits (161), Expect = 8e-11
Identities = 32/87 (36%), Positives = 51/87 (58%)
Frame = +1
Query: 199 DSEKPVKWALEAGYRLIDTAALYLNEDQIGAAVRASGIPREDIFIVTKLPMDNQRDVVKQ 378
++ + V+ A + GYR++DT+ Y + IG A+RASG+ R+DI++VTK ++ D
Sbjct: 14 ETARTVRAAFDLGYRMVDTSGDYGTQSAIGEAIRASGLDRDDIYLVTK--VEETEDAYNA 71
Query: 379 LEKSLARLNMSYVDLYLIHNPVAFNPG 459
+ +L L + Y DL LIH P G
Sbjct: 72 TQANLRELGLDYADLILIHRPPRHGAG 98
>UniRef50_Q9FJK0 Cluster: Aldose reductase-like protein; n=3; core
eudicotyledons|Rep: Aldose reductase-like protein -
Arabidopsis thaliana (Mouse-ear cress)
Length = 316
Score = 68.9 bits (161), Expect = 8e-11
Identities = 47/151 (31%), Positives = 77/151 (50%), Gaps = 12/151 (7%)
Frame = +1
Query: 112 LNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGA 291
L G +IP LG+GT+ QK+ + S V A++ GYR DTA +Y +E+ +G
Sbjct: 8 LRCGETIPLLGMGTYCP-----QKDRESTISA--VHQAIKIGYRHFDTAKIYGSEEALGT 60
Query: 292 A----VRASGIPREDIFIVTKLPMDNQRDVVKQLEKSLARLNMSYVDLYLIHNPVAFNPG 459
A + + R+D+F+ +KL + D + L ++L + + Y+D YL+H P+ PG
Sbjct: 61 ALGQAISYGTVQRDDLFVTSKLWSSDHHDPISALIQTLKTMGLDYLDNYLVHWPIKLKPG 120
Query: 460 F-----KGFDIVDYL---DTWKGMEEAKNLG 528
K + L +TW+GME +G
Sbjct: 121 VSEPIPKEDEFEKDLGIEETWQGMERCLEMG 151
>UniRef50_Q927E1 Cluster: Lin2848 protein; n=13; Listeria|Rep:
Lin2848 protein - Listeria innocua
Length = 280
Score = 68.5 bits (160), Expect = 1e-10
Identities = 38/112 (33%), Positives = 62/112 (55%), Gaps = 2/112 (1%)
Frame = +1
Query: 112 LNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGA 291
LN+G +P G G + DE+ + ++ A++ GYRL DTA+ Y NE ++G
Sbjct: 11 LNNGIEMPRHGFGVYKLTDEQRMRTA--------LETAVDVGYRLFDTASFYHNEKELGD 62
Query: 292 AVRASGIPREDIFIVTKLPMDNQ--RDVVKQLEKSLARLNMSYVDLYLIHNP 441
+SG+ R++ F+ TK+ Q + ++ EKS +L + VDLYL+H P
Sbjct: 63 FFASSGLKRDEFFVTTKMWNTEQGYDETLRAFEKSQKKLQLDQVDLYLVHWP 114
>UniRef50_P70883 Cluster: AkrI; n=1; Butyrivibrio fibrisolvens|Rep:
AkrI - Butyrivibrio fibrisolvens
Length = 172
Score = 68.5 bits (160), Expect = 1e-10
Identities = 50/151 (33%), Positives = 75/151 (49%), Gaps = 8/151 (5%)
Frame = +1
Query: 100 SKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNED 279
++I LN+G +IP G GT+ D+ ++ V+ AL+ GYR IDTAA Y NE
Sbjct: 6 TRIKLNNGTAIPMFGYGTYKIKDQN--------EAYNSVRLALKNGYRHIDTAAFYENEK 57
Query: 280 QIGAAVR----ASGIPREDIFIVTKLPMD--NQRDVVKQLEKSLARLNMSYVDLYLIHNP 441
+ A++ S REDIF+ +K + EK++ + M Y+DLYL+H P
Sbjct: 58 FVANAIKDFMEESQTKREDIFVTSKAWKTELGYDKTLAAFEKTMNEMQMDYLDLYLVHWP 117
Query: 442 V--AFNPGFKGFDIVDYLDTWKGMEEAKNLG 528
AF+ ++ + TWK M E G
Sbjct: 118 ASYAFDDDWENTN----RQTWKAMTEIYKSG 144
>UniRef50_A3C1Z7 Cluster: Putative uncharacterized protein; n=2;
Oryza sativa (japonica cultivar-group)|Rep: Putative
uncharacterized protein - Oryza sativa subsp. japonica
(Rice)
Length = 288
Score = 68.5 bits (160), Expect = 1e-10
Identities = 54/156 (34%), Positives = 83/156 (53%), Gaps = 16/156 (10%)
Frame = +1
Query: 109 SLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNE---- 276
+L+ G +P +G+GT F G + P + V A+EAGYR DTAA+Y E
Sbjct: 5 ALSSGKPMPRVGMGT-ASFP-LGATD--PSTVKDVVLRAIEAGYRHFDTAAVYQTEAILG 60
Query: 277 DQIGAAVRASGIP-REDIFIVTKLPMDNQRD--VVKQLEKSLARLNMSYVDLYLIHNPVA 447
D + AVRA + R++++I +KL + + V+ L ++L ++ M Y+DLYLIH PV+
Sbjct: 61 DAVAEAVRAGLVASRDELYITSKLWVAHAHPGHVLPSLRRALRKMQMEYLDLYLIHFPVS 120
Query: 448 F-------NPGFKGFDIV--DYLDTWKGMEEAKNLG 528
+ + D+V D WK MEE + LG
Sbjct: 121 MRLAEDPESMTYSKDDLVMMDMEGVWKEMEECQRLG 156
>UniRef50_A7D7K7 Cluster: Aldo/keto reductase; n=1; Halorubrum
lacusprofundi ATCC 49239|Rep: Aldo/keto reductase -
Halorubrum lacusprofundi ATCC 49239
Length = 265
Score = 68.5 bits (160), Expect = 1e-10
Identities = 36/91 (39%), Positives = 52/91 (57%), Gaps = 3/91 (3%)
Frame = +1
Query: 193 PGDSEKPVKWALEAGYRLIDTAALYLNEDQIGAAVRASGIPREDIFIVTKLPMDN--QRD 366
P + V ALEAGYR +DTA +Y NE +G + + + R+D+ + TK+ DN D
Sbjct: 18 PAECRATVAAALEAGYRHVDTAQMYDNETAVGEGIATADVDRDDVVVATKIHPDNLAPAD 77
Query: 367 VVKQLEKSLARLNMSYVDLYLIHNPV-AFNP 456
V + KSL RL + VDL +H P A++P
Sbjct: 78 VRETARKSLDRLGLDRVDLLYVHWPTGAYDP 108
>UniRef50_Q9X265 Cluster: Oxidoreductase, aldo/keto reductase
family; n=2; Thermotoga|Rep: Oxidoreductase, aldo/keto
reductase family - Thermotoga maritima
Length = 274
Score = 68.1 bits (159), Expect = 1e-10
Identities = 48/114 (42%), Positives = 68/114 (59%), Gaps = 7/114 (6%)
Frame = +1
Query: 121 GNSIPALGLGTFL--GFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALY---LNEDQI 285
G IPALGLGT+ GF+ + + + +K A++ GY IDTA Y E+ I
Sbjct: 10 GEEIPALGLGTWGIGGFETPDYS--RDEEMVELLKTAIKMGYTHIDTAEYYGGGHTEELI 67
Query: 286 GAAVRASGIPREDIFIVTKL-PMDNQRD-VVKQLEKSLARLNMSYVDLYLIHNP 441
G A++ RED+FIV+K+ P +RD +++ LE +L RL+ YVDLYLIH P
Sbjct: 68 GKAIK--DFRREDLFIVSKVWPTHLRRDDLLRSLENTLKRLDTDYVDLYLIHWP 119
>UniRef50_Q5NLW3 Cluster: Putative oxidoreductase; n=1; Zymomonas
mobilis|Rep: Putative oxidoreductase - Zymomonas mobilis
Length = 273
Score = 68.1 bits (159), Expect = 1e-10
Identities = 48/143 (33%), Positives = 75/143 (52%), Gaps = 2/143 (1%)
Frame = +1
Query: 106 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 285
+ LNDG+S+PA+G G + ++ P +E V + GYR +DTAA Y NE+ +
Sbjct: 7 VVLNDGHSMPAIGQGVY---------QLNPAQAESMVALGYDLGYRAVDTAAWYENEEGV 57
Query: 286 GAAVRASGIPREDIFIVTKL-PMDNQR-DVVKQLEKSLARLNMSYVDLYLIHNPVAFNPG 459
G +R+ FI TKL P D R + L+KS+ L ++ ++LYLIH P
Sbjct: 58 GEGLRSR---HARSFITTKLMPQDMGRVNCFVALDKSIRNLGVTSLNLYLIHWP------ 108
Query: 460 FKGFDIVDYLDTWKGMEEAKNLG 528
G D Y +TW+ + + + +G
Sbjct: 109 --GQDRKRYEETWQTLIQIRAIG 129
>UniRef50_A1RB46 Cluster: 2,5-diketo-D-gluconate reductase; n=1;
Arthrobacter aurescens TC1|Rep: 2,5-diketo-D-gluconate
reductase - Arthrobacter aurescens (strain TC1)
Length = 273
Score = 68.1 bits (159), Expect = 1e-10
Identities = 43/111 (38%), Positives = 61/111 (54%), Gaps = 3/111 (2%)
Frame = +1
Query: 121 GNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGAAVR 300
G ++PA+ LGT L P D + V WAL+ GYR DTAALY E IG A+R
Sbjct: 7 GTALPAITLGTGLR---------PPTDVYRLVGWALDMGYRSFDTAALYGTEAAIGRAIR 57
Query: 301 ASGIPREDIFIVTKL---PMDNQRDVVKQLEKSLARLNMSYVDLYLIHNPV 444
SGI R ++FI K+ ++ V + +E+SL L S+ D+ + H P+
Sbjct: 58 DSGIDRRELFITVKVRGNEYGSRARVHQAIERSLEALGTSFADMVVPHWPL 108
>UniRef50_Q54NR2 Cluster: Aldo-keto reductase; n=3; Dictyostelium
discoideum AX4|Rep: Aldo-keto reductase - Dictyostelium
discoideum AX4
Length = 305
Score = 68.1 bits (159), Expect = 1e-10
Identities = 49/141 (34%), Positives = 69/141 (48%), Gaps = 13/141 (9%)
Frame = +1
Query: 130 IPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGAAVR--- 300
+P LG+GTF K D E +K LE GYR IDTA++Y NE++IG +
Sbjct: 27 MPMLGIGTF-----------KLNDIENIIKVGLENGYRRIDTASMYNNEERIGKVLNEMV 75
Query: 301 -------ASGIPREDIFIVTKLPMDNQ--RDVVKQLEKSLARLNMSYVDLYLIHNP-VAF 450
I RED+FI +K Q + +K E SL +L + Y+D YLIH P V
Sbjct: 76 TKNDGLDGKKIKREDLFITSKCSFMEQGYENALKAFESSLKKLQLDYLDCYLIHWPGVKG 135
Query: 451 NPGFKGFDIVDYLDTWKGMEE 513
G + + TW+ +E+
Sbjct: 136 LDGSDSGNSIQRAQTWRALEK 156
>UniRef50_P91997 Cluster: Putative uncharacterized protein; n=4;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 297
Score = 68.1 bits (159), Expect = 1e-10
Identities = 49/147 (33%), Positives = 75/147 (51%), Gaps = 8/147 (5%)
Frame = +1
Query: 112 LNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGA 291
LN G +IP +G GT+ E V P + AL AGYR+ DTA YLNE ++G
Sbjct: 15 LNSGYNIPFVGFGTYKVTGEN----VPPA-----IDAALTAGYRMFDTAKYYLNEKELGE 65
Query: 292 AVR----ASGIPREDIFIVTKL--PMDNQRDVVKQ-LEKSLARLNMSYVDLYLIHNPVAF 450
A++ G+ R D+F+ +K N R+ + +E+SL L Y+D+YL+H P
Sbjct: 66 ALKILLPKHGLSRSDVFLTSKFFPESKNCREACRGFVEESLQSLQTDYIDMYLVHYPKPN 125
Query: 451 NPGFKGFDIVDYLD-TWKGMEEAKNLG 528
+ + +Y ++ +EEAK G
Sbjct: 126 DSDNDDVNNAEYRKIAYEVLEEAKAAG 152
>UniRef50_Q5T2L2 Cluster: Aldo-keto reductase family 1 member C-like
protein 1; n=14; Eutheria|Rep: Aldo-keto reductase
family 1 member C-like protein 1 - Homo sapiens (Human)
Length = 302
Score = 68.1 bits (159), Expect = 1e-10
Identities = 46/129 (35%), Positives = 67/129 (51%), Gaps = 7/129 (5%)
Frame = +1
Query: 94 KASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN 273
++ + LNDG +P LG GT+ + + K A++ G+R ID+A LY N
Sbjct: 7 QSHSVRLNDGPFMPVLGFGTY------APDHTPKSQAAEATKVAIDVGFRHIDSAYLYQN 60
Query: 274 EDQIGAAV---RASG-IPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIH 435
E+++G A+ A G + RE+IF KL V LE+SL +L YVDL++IH
Sbjct: 61 EEEVGQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIH 120
Query: 436 NPVAF-NPG 459
P A PG
Sbjct: 121 VPFAMKQPG 129
>UniRef50_Q16CS5 Cluster: 2,5-diketo-D-gluconic acid reductase B,
putative; n=3; Bacteria|Rep: 2,5-diketo-D-gluconic acid
reductase B, putative - Roseobacter denitrificans
(strain ATCC 33942 / OCh 114) (Erythrobactersp. (strain
OCh 114)) (Roseobacter denitrificans)
Length = 272
Score = 67.7 bits (158), Expect = 2e-10
Identities = 33/77 (42%), Positives = 48/77 (62%), Gaps = 2/77 (2%)
Frame = +1
Query: 223 ALEAGYRLIDTAALYLNEDQIGAAVRASGIPREDIFIVTKLPMDN--QRDVVKQLEKSLA 396
A E GYR DTA +Y NE + GAA++ +GIPR+ + + TK+ DN + + +E SL
Sbjct: 30 AAEVGYRAFDTAQMYRNEAETGAALKETGIPRDTLCVTTKVENDNYDESKFLASVEASLK 89
Query: 397 RLNMSYVDLYLIHNPVA 447
L + YVD+ L+H P A
Sbjct: 90 ALQLDYVDVLLLHWPPA 106
>UniRef50_A0JX62 Cluster: 2,5-didehydrogluconate reductase; n=9;
Bacteria|Rep: 2,5-didehydrogluconate reductase -
Arthrobacter sp. (strain FB24)
Length = 291
Score = 67.7 bits (158), Expect = 2e-10
Identities = 51/134 (38%), Positives = 70/134 (52%), Gaps = 19/134 (14%)
Frame = +1
Query: 103 KISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQ 282
++SLN+G I LG G + +V P D+ V ALEAGYR DTAA+Y NE
Sbjct: 6 RLSLNNGVLIDQLGFGLY---------KVPPADAAGLVTMALEAGYRHFDTAAMYGNETG 56
Query: 283 IGAAVRA------------SG-----IPREDIFIVTKLPMDNQ--RDVVKQLEKSLARLN 405
+G A+ A SG + RED+F+ TK+ D+ ++ + S++ L
Sbjct: 57 VGKAIGALAGFAGGGPAGGSGEAAPSLSREDLFVTTKVWNDDHGYDATMRAFDTSMSNLG 116
Query: 406 MSYVDLYLIHNPVA 447
M YVDLYLIH P A
Sbjct: 117 MEYVDLYLIHWPCA 130
>UniRef50_Q21274 Cluster: Putative uncharacterized protein; n=1;
Caenorhabditis elegans|Rep: Putative uncharacterized
protein - Caenorhabditis elegans
Length = 301
Score = 67.7 bits (158), Expect = 2e-10
Identities = 53/132 (40%), Positives = 70/132 (53%), Gaps = 7/132 (5%)
Frame = +1
Query: 67 LSEATTGGGKASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRL 246
+S T G A K S DG +P +GLG + E Q D + ++ AL++GYR
Sbjct: 1 MSVFTNVVGGAFKFS--DGYEMPKIGLG--ISRIETQQ------DLDVSIEAALKSGYRQ 50
Query: 247 IDTAALYLNEDQIGAAVR----ASGIPREDIFIVTKLPMDNQRDV---VKQLEKSLARLN 405
DTA LY NE +G +++ G+ RED+FI TK+ N+ V KQL SLA L
Sbjct: 51 FDTANLYKNETFLGNSLKKYLPQFGLTREDVFITTKVRTLNENTVEETEKQLANSLATLQ 110
Query: 406 MSYVDLYLIHNP 441
YVDL LIH P
Sbjct: 111 TDYVDLLLIHYP 122
>UniRef50_Q17DN1 Cluster: Aldo-keto reductase; n=1; Aedes
aegypti|Rep: Aldo-keto reductase - Aedes aegypti
(Yellowfever mosquito)
Length = 284
Score = 67.7 bits (158), Expect = 2e-10
Identities = 42/116 (36%), Positives = 65/116 (56%), Gaps = 5/116 (4%)
Frame = +1
Query: 94 KASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLN 273
KA + LN+G +P LGLGT+L K G+ + +K A++AGYR IDTA Y N
Sbjct: 4 KAPMVKLNNGLEMPVLGLGTWLS---------KEGEGVEAIKAAIDAGYRHIDTAYFYQN 54
Query: 274 EDQIGAAVRA---SGIP-REDIFIVTK-LPMDNQRDVVKQLEKSLARLNMSYVDLY 426
E ++G A+RA G+ RED+F+ TK + D + + + L ++ Y+D +
Sbjct: 55 EKEVGEAIRAKIEEGVVCREDLFVTTKFIDWDTKNLMPYDADGKLQFSDVDYIDTW 110
>UniRef50_Q75E75 Cluster: ABL209Cp; n=1; Eremothecium gossypii|Rep:
ABL209Cp - Ashbya gossypii (Yeast) (Eremothecium
gossypii)
Length = 310
Score = 67.7 bits (158), Expect = 2e-10
Identities = 51/143 (35%), Positives = 70/143 (48%), Gaps = 8/143 (5%)
Frame = +1
Query: 112 LNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGA 291
L+DG IP++GLG + +V + V ALE GYRL D+A Y NED +
Sbjct: 15 LSDGTQIPSVGLGVY---------QVSEQTVQDLVYEALEVGYRLFDSAQAYHNEDGVAR 65
Query: 292 AV-----RASGIPREDIFIVTKLPMDNQ--RDVVKQLEKSL-ARLNMSYVDLYLIHNPVA 447
+ A G RED++ TK+ N K LEKSL A + Y+DL L+H P++
Sbjct: 66 GIAAWLKHAPGRRREDVYFTTKINTQNHGYEATKKSLEKSLHAAGPLGYIDLVLVHAPMS 125
Query: 448 FNPGFKGFDIVDYLDTWKGMEEA 516
D L TW+ +EEA
Sbjct: 126 --------DRTRRLGTWQALEEA 140
>UniRef50_Q1M4Z6 Cluster: Putative aldo-keto reductase/oxidase; n=1;
Rhizobium leguminosarum bv. viciae 3841|Rep: Putative
aldo-keto reductase/oxidase - Rhizobium leguminosarum
bv. viciae (strain 3841)
Length = 274
Score = 67.3 bits (157), Expect = 2e-10
Identities = 38/99 (38%), Positives = 56/99 (56%), Gaps = 2/99 (2%)
Frame = +1
Query: 199 DSEKPVKWALEAGYRLIDTAALYLNEDQIGAAVRASGIPREDIFIVTKLPMDNQRD--VV 372
++ + V WALEAG R IDTA Y NE + ++ +G+ R +IFI TK+ DN V+
Sbjct: 24 EAHQGVIWALEAGCRHIDTAQGYGNEQDVARGIKDAGVARNEIFITTKVKPDNYGPGAVM 83
Query: 373 KQLEKSLARLNMSYVDLYLIHNPVAFNPGFKGFDIVDYL 489
+ +SL +L + VDL L+H P N + + DYL
Sbjct: 84 PSVRESLEKLRVDQVDLLLLHWPSPHNK----YPLADYL 118
>UniRef50_A0L1A2 Cluster: Aldo/keto reductase; n=8;
Gammaproteobacteria|Rep: Aldo/keto reductase -
Shewanella sp. (strain ANA-3)
Length = 280
Score = 67.3 bits (157), Expect = 2e-10
Identities = 43/108 (39%), Positives = 58/108 (53%), Gaps = 2/108 (1%)
Frame = +1
Query: 127 SIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGAAVRAS 306
++P LG GTF +K + V ALE G R IDTA +Y NE +G A+ S
Sbjct: 16 AMPMLGTGTF---------RLKDNAAFDAVLMALEEGSRHIDTAQIYGNEQAVGDAINTS 66
Query: 307 GIPREDIFIVTKLPMDN--QRDVVKQLEKSLARLNMSYVDLYLIHNPV 444
GIPRE++FI TK+ +N + + SL L Y+DL LIH P+
Sbjct: 67 GIPREELFITTKVWTENLTKERFETSVIDSLTALQTKYLDLLLIHWPL 114
>UniRef50_Q7QVQ9 Cluster: GLP_302_44328_45269; n=1; Giardia lamblia
ATCC 50803|Rep: GLP_302_44328_45269 - Giardia lamblia
ATCC 50803
Length = 313
Score = 67.3 bits (157), Expect = 2e-10
Identities = 54/158 (34%), Positives = 81/158 (51%), Gaps = 20/158 (12%)
Frame = +1
Query: 157 LGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGAAV------RASGIPR 318
LGF G + P + V+ AL GYR ID A +Y NE+ IG A +SGI R
Sbjct: 7 LGF---GTWQAPPEAVQTAVETALMTGYRHIDCAYVYQNEEAIGRAFGKIFKDASSGIKR 63
Query: 319 EDIFIVTKLPMDNQRD--VVKQLEKSLARLNMSYVDLYLIHNPVAF------------NP 456
ED++I +KL N R V +Q +K+++ L + Y+DL+L+H P+AF
Sbjct: 64 EDVWITSKLWNYNHRPELVREQCKKTMSDLQVDYLDLFLVHWPLAFVRNDVGDLFPKDAE 123
Query: 457 GFKGFDIVDYLDTWKGMEEAKNLGPS*IYRHI*LQHHT 570
G + V DTW+ ME+ G + +HI + ++T
Sbjct: 124 GRAMLEKVPLADTWRAMEQLVEEG---LVKHIGVSNYT 158
>UniRef50_Q4FY75 Cluster: Aldo-keto reductase-like protein; n=5;
Trypanosomatidae|Rep: Aldo-keto reductase-like protein -
Leishmania major strain Friedlin
Length = 372
Score = 66.9 bits (156), Expect = 3e-10
Identities = 44/120 (36%), Positives = 64/120 (53%), Gaps = 6/120 (5%)
Frame = +1
Query: 103 KISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQ 282
+I++ D ++IP LG GT+ + ++ V +AL GYR +D A Y NE
Sbjct: 21 RIAMRDSHTIPQLGFGTY---------RLPVSEATDAVAFALSCGYRHVDCAKAYGNEAA 71
Query: 283 IGAAV----RASGIPREDIFIVTKL-PMDNQRDVVKQL-EKSLARLNMSYVDLYLIHNPV 444
+G A+ R RED+F+ +KL P D D V+ +LA L + Y+DLYLIH PV
Sbjct: 72 VGEALAQALRTRCTRREDLFVTSKLWPTDQHPDHVEAACRATLAALQLDYLDLYLIHWPV 131
>UniRef50_UPI0000D9A956 Cluster: PREDICTED: similar to aldo-keto
reductase family 1, member B10, partial; n=1; Macaca
mulatta|Rep: PREDICTED: similar to aldo-keto reductase
family 1, member B10, partial - Macaca mulatta
Length = 275
Score = 66.5 bits (155), Expect = 4e-10
Identities = 40/97 (41%), Positives = 60/97 (61%), Gaps = 12/97 (12%)
Frame = +1
Query: 196 GDSEKPVKWALEAGYRLIDTAALYLNEDQIGAAVRAS----GIPREDIFIVTKLPMDN-- 357
G ++ VK A++AGYR ID A +Y NE ++G A++ + RED+FIV+K+ M +
Sbjct: 46 GKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEQAVKREDLFIVSKVHMAHWL 105
Query: 358 -----QRDVV-KQLEKSLARLNMSYVDLYLIHNPVAF 450
+R +V K EK+L L +SY+D+YLIH P F
Sbjct: 106 WTTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGF 142
>UniRef50_Q9HM42 Cluster: Alcohol dehydrogenase related protein;
n=1; Thermoplasma acidophilum|Rep: Alcohol dehydrogenase
related protein - Thermoplasma acidophilum
Length = 284
Score = 66.5 bits (155), Expect = 4e-10
Identities = 40/109 (36%), Positives = 61/109 (55%), Gaps = 2/109 (1%)
Frame = +1
Query: 121 GNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGAAVR 300
G + +G+GT+ E ++ + +++AL+ G IDTA +Y ED +G A++
Sbjct: 13 GRKVSVIGVGTW-------SLEGSRSENVRSIRYALDHGVNFIDTAEMYGTEDIVGEAIK 65
Query: 301 ASGIPREDIFIVTKL-PMD-NQRDVVKQLEKSLARLNMSYVDLYLIHNP 441
G RED+FI TK+ P DV+K E+SL +L YVDLY +H P
Sbjct: 66 --GYRREDLFIATKVWPTHFAYHDVLKSCEESLKKLGTDYVDLYQLHWP 112
>UniRef50_Q09632 Cluster: Probable oxidoreductase ZK1290.5; n=2;
Caenorhabditis|Rep: Probable oxidoreductase ZK1290.5 -
Caenorhabditis elegans
Length = 321
Score = 66.5 bits (155), Expect = 4e-10
Identities = 32/72 (44%), Positives = 46/72 (63%), Gaps = 1/72 (1%)
Frame = +1
Query: 229 EAGYRLIDTAALYLNEDQIGAAVRASGIPREDIFIVTKL-PMDNQRDVVKQLEKSLARLN 405
+ GYRLIDTA Y E Q+G AV+ +PRE++F+ TKL P+D +V + S +L
Sbjct: 37 KCGYRLIDTAKRYGVEKQLGIAVKNCSVPREEMFLSTKLWPVDCGDEVYNAFQTSCEKLQ 96
Query: 406 MSYVDLYLIHNP 441
Y+D+Y+IH P
Sbjct: 97 TDYLDMYMIHMP 108
>UniRef50_A7D6Q0 Cluster: Aldo/keto reductase; n=1; Halorubrum
lacusprofundi ATCC 49239|Rep: Aldo/keto reductase -
Halorubrum lacusprofundi ATCC 49239
Length = 309
Score = 66.1 bits (154), Expect = 6e-10
Identities = 44/113 (38%), Positives = 65/113 (57%), Gaps = 2/113 (1%)
Frame = +1
Query: 109 SLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIG 288
+L G+++PALGLGT+ D++ DS V+ AL +GY IDTA Y NE+ IG
Sbjct: 38 TLPSGDTLPALGLGTYALDDDQ------IADS---VRAALSSGYTHIDTAEGYHNEEAIG 88
Query: 289 AAVRASGIPREDIFIVTKLPMDN--QRDVVKQLEKSLARLNMSYVDLYLIHNP 441
+ + R+D+F+ +K+ N +++ E SL RL Y+DLYLIH P
Sbjct: 89 EVL--AEYDRDDVFLTSKVLAKNLGYESLIQSCEASLERLETDYLDLYLIHWP 139
>UniRef50_P38715 Cluster: NADPH-dependent aldose reductase GRE3;
n=39; cellular organisms|Rep: NADPH-dependent aldose
reductase GRE3 - Saccharomyces cerevisiae (Baker's
yeast)
Length = 327
Score = 66.1 bits (154), Expect = 6e-10
Identities = 46/124 (37%), Positives = 74/124 (59%), Gaps = 6/124 (4%)
Frame = +1
Query: 97 ASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNE 276
+S ++LN+G +P +GLG + K K+V + A++ GYRL D A Y NE
Sbjct: 2 SSLVTLNNGLKMPLVGLGCW-----KIDKKV----CANQIYEAIKLGYRLFDGACDYGNE 52
Query: 277 DQIGAAVR---ASG-IPREDIFIVTKLPMD-NQRDVVK-QLEKSLARLNMSYVDLYLIHN 438
++G +R + G + R+DIF+V+KL + + D VK L+K+L+ + + Y+DLY IH
Sbjct: 53 KEVGEGIRKAISEGLVSRKDIFVVSKLWNNFHHPDHVKLALKKTLSDMGLDYLDLYYIHF 112
Query: 439 PVAF 450
P+AF
Sbjct: 113 PIAF 116
>UniRef50_Q7ZWA4 Cluster: Zgc:56622; n=6; cellular organisms|Rep:
Zgc:56622 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 289
Score = 65.7 bits (153), Expect = 8e-10
Identities = 46/118 (38%), Positives = 62/118 (52%), Gaps = 16/118 (13%)
Frame = +1
Query: 223 ALEAGYRLIDTAALYLNEDQIGAAVR---ASG-IPREDIFIVTKL--PMDNQRDVVKQLE 384
A+ AGYR IDTA Y NE +G A++ G I R+D+FIV+KL D+
Sbjct: 9 AIAAGYRHIDTAFCYRNEVDVGMAIQNKIQQGIIRRQDMFIVSKLWGTHHAPEDIPVCFN 68
Query: 385 KSLARLNMSYVDLYLIHNPVAFN-------PGFKGFDI---VDYLDTWKGMEEAKNLG 528
KSL+ L + Y+D YL+H PV P G + +DY+D W+GME K G
Sbjct: 69 KSLSDLQLDYLDQYLVHFPVGLKKVGDELFPERDGKILTTDIDYVDVWRGMEALKATG 126
>UniRef50_Q2H7A8 Cluster: Putative uncharacterized protein; n=1;
Chaetomium globosum|Rep: Putative uncharacterized
protein - Chaetomium globosum (Soil fungus)
Length = 289
Score = 65.3 bits (152), Expect = 1e-09
Identities = 49/142 (34%), Positives = 71/142 (50%), Gaps = 1/142 (0%)
Frame = +1
Query: 106 ISLNDGNSIPA-LGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQ 282
+ L DGN IP LG TF GQ V D K V +E G+ +D A +Y E++
Sbjct: 6 LRLRDGNQIPLDLGDTTF------GQGLV---DLTKAV---IEKGFYHLDCAEMYGTEEE 53
Query: 283 IGAAVRASGIPREDIFIVTKLPMDNQRDVVKQLEKSLARLNMSYVDLYLIHNPVAFNPGF 462
+ A++ SG+PRE +FI K+ D+ +++SL ++ +Y DLYLIH P F
Sbjct: 54 VAIAIKESGVPREKLFITNKVAQGID-DIEAAIDQSLQKMQTNYFDLYLIHIP------F 106
Query: 463 KGFDIVDYLDTWKGMEEAKNLG 528
D+ WK ME + G
Sbjct: 107 FAKSEEDFQRAWKTMEGIQKAG 128
>UniRef50_UPI0000DB6EE9 Cluster: PREDICTED: similar to C35D10.6;
n=2; Endopterygota|Rep: PREDICTED: similar to C35D10.6 -
Apis mellifera
Length = 292
Score = 64.9 bits (151), Expect = 1e-09
Identities = 45/121 (37%), Positives = 66/121 (54%), Gaps = 7/121 (5%)
Frame = +1
Query: 106 ISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQI 285
+ L+ G +P +G GT+ +G++ V + V +L G+R IDTA Y NE+ I
Sbjct: 8 VCLSSGYDMPLIGFGTY---KIQGRELVY-----QVVDESLNVGFRSIDTAVGYRNEEDI 59
Query: 286 GAAVR----ASGIPREDIFIVTKLPMDNQRD---VVKQLEKSLARLNMSYVDLYLIHNPV 444
G A++ + R DIFI TKLP D + + ++KSL N +Y+DLYLIH P
Sbjct: 60 GYALKNLLPKYNLQRSDIFITTKLPPSVNGDPKGIEQCVQKSLKAFNTTYIDLYLIHWPG 119
Query: 445 A 447
A
Sbjct: 120 A 120
>UniRef50_Q9U2J5 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 339
Score = 64.9 bits (151), Expect = 1e-09
Identities = 46/165 (27%), Positives = 86/165 (52%), Gaps = 21/165 (12%)
Frame = +1
Query: 97 ASKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNE 276
A ++LN G +P +G GT+ ++ + + V+ ALEAGYR ID+A + N+
Sbjct: 4 ADTVTLNSGYEMPVIGYGTW---------QLPKNLAAERVRDALEAGYRHIDSALSFKNQ 54
Query: 277 DQIGAAV----RASGIPREDIFIVTKL--PMDNQRDVVKQLEKSLARLNMSYVDLYLIHN 438
+++ A + + + RE++F+ +K+ ++ ++Q+++ L +Y+DL +IH
Sbjct: 55 EEVAAGIKDWCKIRKVRREELFLSSKIWNTYHSRNRCMQQIDEMLEIFETTYMDLIVIHW 114
Query: 439 PVAF----NPGFKG-----------FDIVDYLDTWKGMEEAKNLG 528
P + PG +G + VDYL+TWK +E+A G
Sbjct: 115 PFGWAEDEPPGERGLWPRGANGKMRYSDVDYLETWKALEDAHRSG 159
>UniRef50_Q76L36 Cluster: Conjugated polyketone reductase C2; n=1;
Candida parapsilosis|Rep: Conjugated polyketone
reductase C2 - Candida parapsilosis (Yeast)
Length = 307
Score = 64.9 bits (151), Expect = 1e-09
Identities = 35/107 (32%), Positives = 58/107 (54%), Gaps = 6/107 (5%)
Frame = +1
Query: 226 LEAGYRLIDTAALYLNEDQIGAAVRASGIPREDIFIVTKLP------MDNQRDVVKQLEK 387
L+ G+R IDTA Y + ++G A++ + +PREDI++ TK + ++K
Sbjct: 50 LKLGFRHIDTAEAYNTQKEVGEALKRTDVPREDIWVTTKYSPGWGSIKAYSKSPSDSIDK 109
Query: 388 SLARLNMSYVDLYLIHNPVAFNPGFKGFDIVDYLDTWKGMEEAKNLG 528
+LA+L + YVDL+LIH+P G+ + W+ + EAK G
Sbjct: 110 ALAQLGVDYVDLFLIHSPFFTTEQTHGYTLE---QAWEALVEAKKAG 153
>UniRef50_Q2CAL9 Cluster: 2,5-didehydrogluconate reductase; n=2;
Oceanicola granulosus HTCC2516|Rep:
2,5-didehydrogluconate reductase - Oceanicola granulosus
HTCC2516
Length = 275
Score = 64.5 bits (150), Expect = 2e-09
Identities = 39/106 (36%), Positives = 58/106 (54%), Gaps = 2/106 (1%)
Frame = +1
Query: 130 IPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGAAVRASG 309
+P LG GT+ +G+ D + ALE GYR +DTA Y E ++G A+R +G
Sbjct: 12 MPGLGFGTY---GRQGE------DGISAILCALETGYRHLDTAQDYDTEAEVGEAIRRAG 62
Query: 310 IPREDIFIVTKLPMDN--QRDVVKQLEKSLARLNMSYVDLYLIHNP 441
+PRE +F+ TK+ N D+V + +SL + + DL LIH P
Sbjct: 63 LPREALFVTTKVRPANFGPGDLVPSVARSLETMGLDRADLVLIHWP 108
>UniRef50_Q9ZUJ6 Cluster: T2K10.1 protein; n=16; core
eudicotyledons|Rep: T2K10.1 protein - Arabidopsis
thaliana (Mouse-ear cress)
Length = 176
Score = 64.1 bits (149), Expect = 2e-09
Identities = 46/138 (33%), Positives = 69/138 (50%), Gaps = 14/138 (10%)
Frame = +1
Query: 157 LGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQIGAAVRAS---GI--PRE 321
LGF +P ++ V A++ GYR DT+ Y E+ IG A+ + G+ R
Sbjct: 24 LGFGTAASPLPEPTMLKETVIEAIKLGYRHFDTSPRYQTEEPIGEALAEAVSLGLVRSRS 83
Query: 322 DIFIVTKLPMDNQRD--VVKQLEKSLARLNMSYVDLYLIHNPVAFNPGFKGFDI------ 477
+ F+ TKL + VV +++SL L + Y+DLY+IH PV+ PG F I
Sbjct: 84 EFFVTTKLWCADAHGGLVVPAIKRSLKNLKLDYLDLYIIHWPVSSKPGKYKFPIDEDDFM 143
Query: 478 -VDYLDTWKGMEEAKNLG 528
+D+ W MEE + LG
Sbjct: 144 PMDFEVVWSEMEECQRLG 161
>UniRef50_P28475 Cluster: NADP-dependent D-sorbitol-6-phosphate
dehydrogenase; n=71; Magnoliophyta|Rep: NADP-dependent
D-sorbitol-6-phosphate dehydrogenase - Malus domestica
(Apple) (Malus sylvestris)
Length = 310
Score = 64.1 bits (149), Expect = 2e-09
Identities = 50/161 (31%), Positives = 81/161 (50%), Gaps = 18/161 (11%)
Frame = +1
Query: 100 SKISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNED 279
S ++L+ G +P +GLG + ++ KEV + A++ GYR D AA Y +E
Sbjct: 2 STVTLSSGYEMPVIGLGLWR-LEKDELKEV--------ILNAIKIGYRHFDCAAHYKSEA 52
Query: 280 QIGAAV----RASGIPREDIFIVTKLPMDNQRDVVKQLEKSLARLNMSYVDLYLIHNP-- 441
+G A+ + + RE++FI TK+ + VV+ + SL +L + Y+DLYL+H P
Sbjct: 53 DVGEALAEAFKTGLVKREELFITTKIWNSDHGHVVEACKNSLEKLQIDYLDLYLVHYPMP 112
Query: 442 -----VAFNPGFKGFDIVDYLD-------TWKGMEEAKNLG 528
+ G D V +D TW+GME+ +LG
Sbjct: 113 TKHNAIGKTASLLGEDKVLDIDVTISLQQTWEGMEKTVSLG 153
>UniRef50_Q1DLF1 Cluster: Putative uncharacterized protein; n=1;
Coccidioides immitis|Rep: Putative uncharacterized
protein - Coccidioides immitis
Length = 324
Score = 63.7 bits (148), Expect = 3e-09
Identities = 48/106 (45%), Positives = 55/106 (51%), Gaps = 5/106 (4%)
Frame = +1
Query: 115 NDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALY---LNEDQI 285
N IPA GLGTF D E DS V AL+ GYR ID A Y E I
Sbjct: 11 NTSIRIPARGLGTFQ-VDPSLYPEGSVKDS---VLHALKIGYRHIDAALAYGWGSVERGI 66
Query: 286 GAAVRASGIPREDIFIVTKLP--MDNQRDVVKQLEKSLARLNMSYV 417
GAA+RASG+PRED+F+VTKL DV + SL L + YV
Sbjct: 67 GAAIRASGVPREDVFVVTKLHNCFHAPEDVEVGMNMSLKNLGLGYV 112
>UniRef50_A5VK30 Cluster: 2,5-didehydrogluconate reductase; n=2;
Lactobacillus reuteri|Rep: 2,5-didehydrogluconate
reductase - Lactobacillus reuteri F275
Length = 300
Score = 63.3 bits (147), Expect = 4e-09
Identities = 44/121 (36%), Positives = 66/121 (54%), Gaps = 7/121 (5%)
Frame = +1
Query: 103 KISLNDGNSIPALGLGTFLGFDEKGQKEVKPGDSEKPVKWALEAGYRLIDTAALYLNEDQ 282
KI LN+G+ IP LGLG + + ++++ VK A+ Y LIDTA Y NE
Sbjct: 12 KIKLNNGHLIPQLGLGVW---------KASLAETQQMVKEAIMNDYVLIDTAKQYGNEAA 62
Query: 283 IGAAV----RASGIPREDIFIVTKLPMDNQRDVVK---QLEKSLARLNMSYVDLYLIHNP 441
+G + +A+G R+ IF+ TK+ +Q D K + + L +L +YVDL L+H P
Sbjct: 63 VGQGIQDGFKATGRKRDSIFLTTKIFNGDQGDYDKLRQAVNEQLKKLQTNYVDLLLLHWP 122
Query: 442 V 444
V
Sbjct: 123 V 123
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 592,370,647
Number of Sequences: 1657284
Number of extensions: 12096614
Number of successful extensions: 35458
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 33669
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 34874
length of database: 575,637,011
effective HSP length: 96
effective length of database: 416,537,747
effective search space used: 40404161459
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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