Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= bmov10i07
(640 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI00015B5DA8 Cluster: PREDICTED: similar to CG12068-PA... 124 2e-27
UniRef50_UPI0000D5679E Cluster: PREDICTED: similar to CG12068-PA... 124 2e-27
UniRef50_UPI0000DB702A Cluster: PREDICTED: similar to CG12068-PA... 118 1e-25
UniRef50_Q9VAH3 Cluster: CG12068-PA; n=2; Sophophora|Rep: CG1206... 117 3e-25
UniRef50_Q02338 Cluster: D-beta-hydroxybutyrate dehydrogenase, m... 89 1e-16
UniRef50_Q7Q4T3 Cluster: ENSANGP00000017799; n=1; Anopheles gamb... 87 3e-16
UniRef50_A7SKS9 Cluster: Predicted protein; n=1; Nematostella ve... 84 2e-15
UniRef50_Q80XN0 Cluster: D-beta-hydroxybutyrate dehydrogenase, m... 83 4e-15
UniRef50_Q20012 Cluster: Putative uncharacterized protein dhs-20... 81 2e-14
UniRef50_UPI0000F2B8EE Cluster: PREDICTED: hypothetical protein;... 81 2e-14
UniRef50_Q60M45 Cluster: Putative uncharacterized protein CBG233... 81 2e-14
UniRef50_UPI0000F2B793 Cluster: PREDICTED: similar to 17-beta hy... 81 3e-14
UniRef50_UPI0000E8001E Cluster: PREDICTED: hypothetical protein;... 79 7e-14
UniRef50_A7SQ85 Cluster: Predicted protein; n=1; Nematostella ve... 79 7e-14
UniRef50_UPI0000ECB04E Cluster: Estradiol 17-beta-dehydrogenase ... 77 4e-13
UniRef50_A1I773 Cluster: Oxidoreductase, short-chain dehydrogena... 76 6e-13
UniRef50_Q5EB01 Cluster: Zgc:113142; n=4; Clupeocephala|Rep: Zgc... 75 1e-12
UniRef50_A5FMQ8 Cluster: Short-chain dehydrogenase/reductase SDR... 75 2e-12
UniRef50_Q6P0H9 Cluster: Hydroxysteroid 11-beta dehydrogenase 2;... 74 3e-12
UniRef50_A7S3H1 Cluster: Predicted protein; n=1; Nematostella ve... 73 4e-12
UniRef50_UPI000045B9B2 Cluster: COG1028: Dehydrogenases with dif... 73 6e-12
UniRef50_UPI000065ECA5 Cluster: Homolog of Homo sapiens "D-beta-... 73 6e-12
UniRef50_A7RIH3 Cluster: Predicted protein; n=1; Nematostella ve... 73 6e-12
UniRef50_UPI000069F00A Cluster: Estradiol 17-beta-dehydrogenase ... 73 8e-12
UniRef50_Q97DY5 Cluster: Short-chain alcohol dehydrogenase famil... 73 8e-12
UniRef50_A1UBR0 Cluster: Short-chain dehydrogenase/reductase SDR... 72 1e-11
UniRef50_A1IEM4 Cluster: Oxidoreductase, short-chain dehydrogena... 72 1e-11
UniRef50_Q9HYR5 Cluster: Probable short chain dehydrogenase; n=4... 71 2e-11
UniRef50_P50169 Cluster: Retinol dehydrogenase 3; n=25; Tetrapod... 71 2e-11
UniRef50_Q6GMC4 Cluster: MGC81883 protein; n=2; Xenopus|Rep: MGC... 70 4e-11
UniRef50_A0NKJ7 Cluster: Short-chain dehydrogenase; n=2; Oenococ... 70 5e-11
UniRef50_A6E8Y7 Cluster: Short-chain dehydrogenase; n=1; Pedobac... 69 1e-10
UniRef50_Q9GQA9 Cluster: Microsomal retinol dehydrogenase 2; n=3... 68 2e-10
UniRef50_Q1PLL0 Cluster: 17-beta hydroxysteroid dehydrogenase 2;... 68 2e-10
UniRef50_A3UHW8 Cluster: Oxidoreductase, short-chain dehydrogena... 68 2e-10
UniRef50_A0KBT1 Cluster: Short-chain dehydrogenase/reductase SDR... 68 2e-10
UniRef50_Q8U4K9 Cluster: Alcohol dehydrogenase, short chain; n=2... 68 2e-10
UniRef50_Q1IZR4 Cluster: Short-chain dehydrogenase/reductase SDR... 67 3e-10
UniRef50_O16881 Cluster: Dehydrogenases, short chain protein 16;... 67 3e-10
UniRef50_Q92781 Cluster: 11-cis retinol dehydrogenase; n=60; Eut... 67 3e-10
UniRef50_A6Q6X0 Cluster: Oxidoreductase; n=4; Proteobacteria|Rep... 67 4e-10
UniRef50_A7SRY0 Cluster: Predicted protein; n=3; Nematostella ve... 66 5e-10
UniRef50_Q72GV3 Cluster: Corticosteroid 11-beta-dehydrogenase; n... 66 7e-10
UniRef50_A1UA98 Cluster: Short-chain dehydrogenase/reductase SDR... 66 7e-10
UniRef50_A7RSA6 Cluster: Predicted protein; n=1; Nematostella ve... 66 7e-10
UniRef50_UPI00006A0336 Cluster: D-beta-hydroxybutyrate dehydroge... 65 1e-09
UniRef50_UPI00003639C7 Cluster: 11-cis retinol dehydrogenase (EC... 65 1e-09
UniRef50_Q7K3N4 Cluster: GH26015p; n=2; Sophophora|Rep: GH26015p... 65 1e-09
UniRef50_A5V3K8 Cluster: Short-chain dehydrogenase/reductase SDR... 65 2e-09
UniRef50_Q801X5 Cluster: 11beta hydroxysteroid dehydrogenase; n=... 64 2e-09
UniRef50_Q081K4 Cluster: Short-chain dehydrogenase/reductase SDR... 64 2e-09
UniRef50_Q2JVU3 Cluster: Oxidoreductase, short chain dehydrogena... 64 3e-09
UniRef50_A7RZX3 Cluster: Predicted protein; n=2; Nematostella ve... 64 3e-09
UniRef50_O14756 Cluster: Hydroxysteroid 17-beta dehydrogenase 6 ... 64 3e-09
UniRef50_Q0AKR3 Cluster: Short-chain dehydrogenase/reductase SDR... 64 4e-09
UniRef50_O01758 Cluster: Dehydrogenases, short chain protein 2, ... 64 4e-09
UniRef50_A5DIM4 Cluster: Putative uncharacterized protein; n=1; ... 64 4e-09
UniRef50_A1ZFM2 Cluster: Oxidoreductase; n=1; Microscilla marina... 63 5e-09
UniRef50_A2TZE3 Cluster: Putative dehydrogenase; n=1; Polaribact... 63 6e-09
UniRef50_A7SME4 Cluster: Predicted protein; n=8; Nematostella ve... 63 6e-09
UniRef50_P37059 Cluster: Estradiol 17-beta-dehydrogenase 2; n=16... 63 6e-09
UniRef50_Q166N1 Cluster: Oxidoreductase, putative; n=2; Rhodobac... 62 8e-09
UniRef50_UPI0000587D40 Cluster: PREDICTED: similar to Retinol de... 62 1e-08
UniRef50_Q4S323 Cluster: Chromosome 3 SCAF14756, whole genome sh... 62 1e-08
UniRef50_Q9PBQ8 Cluster: Oxidoreductase; n=11; Proteobacteria|Re... 62 1e-08
UniRef50_Q222H9 Cluster: Short-chain dehydrogenase/reductase SDR... 62 1e-08
UniRef50_Q0SDG7 Cluster: Short chain dehydrogenase; n=3; Nocardi... 62 1e-08
UniRef50_A5V6Z5 Cluster: Short-chain dehydrogenase/reductase SDR... 62 1e-08
UniRef50_A7RYH1 Cluster: Predicted protein; n=7; Eumetazoa|Rep: ... 62 1e-08
UniRef50_UPI0000E47390 Cluster: PREDICTED: similar to retinol de... 61 2e-08
UniRef50_Q82RJ3 Cluster: Putative dehydrogenase; n=1; Streptomyc... 61 2e-08
UniRef50_Q2YCW1 Cluster: Short-chain dehydrogenase/reductase SDR... 61 2e-08
UniRef50_A1G780 Cluster: Short-chain dehydrogenase/reductase SDR... 61 2e-08
UniRef50_Q3IVD0 Cluster: Short-chain alcohol dehydrogenases; n=2... 61 3e-08
UniRef50_Q1WVR8 Cluster: Short chain dehydrogenase; n=1; Lactoba... 61 3e-08
UniRef50_Q1DE83 Cluster: Oxidoreductase, short chain dehydrogena... 61 3e-08
UniRef50_Q0BWW4 Cluster: Oxidoreductase, short chain dehydrogena... 61 3e-08
UniRef50_A5WC68 Cluster: Short-chain dehydrogenase/reductase SDR... 61 3e-08
UniRef50_Q3AXB5 Cluster: Oxidoreductase; n=4; Synechococcus|Rep:... 60 3e-08
UniRef50_Q12HC0 Cluster: Short-chain dehydrogenase/reductase SDR... 60 3e-08
UniRef50_A6F0V6 Cluster: Short-chain dehydrogenase/reductase SDR... 60 3e-08
UniRef50_A4BGV8 Cluster: Short chain dehydrogenase; n=1; Reineke... 60 3e-08
UniRef50_A7DQK3 Cluster: Short-chain dehydrogenase/reductase SDR... 60 3e-08
UniRef50_Q9BPW9 Cluster: Dehydrogenase/reductase SDR family memb... 60 3e-08
UniRef50_Q8RS26 Cluster: Benzil reductase; n=16; Bacillus cereus... 60 4e-08
UniRef50_Q0AQK5 Cluster: Short-chain dehydrogenase/reductase SDR... 60 4e-08
UniRef50_Q07KD0 Cluster: Short-chain dehydrogenase/reductase SDR... 60 4e-08
UniRef50_A7IEU0 Cluster: Short-chain dehydrogenase/reductase SDR... 60 4e-08
UniRef50_A6EJ86 Cluster: Short-chain dehydrogenase/reductase SDR... 60 4e-08
UniRef50_A4WGJ7 Cluster: Short-chain dehydrogenase/reductase SDR... 60 4e-08
UniRef50_Q6RH38 Cluster: 17b-hydroxysteroid dehydrogenase type I... 60 6e-08
UniRef50_Q127D6 Cluster: Short-chain dehydrogenase/reductase SDR... 60 6e-08
UniRef50_A6FXI4 Cluster: Short-chain dehydrogenase/reductase SDR... 60 6e-08
UniRef50_A4A7Q2 Cluster: Short-chain dehydrogenase/reductase SDR... 60 6e-08
UniRef50_Q8NEX9 Cluster: Retinol dehydrogenase similar protein; ... 60 6e-08
UniRef50_UPI0000E46C37 Cluster: PREDICTED: hypothetical protein;... 59 8e-08
UniRef50_Q4JV39 Cluster: Putative dehydrogenase related to short... 59 8e-08
UniRef50_Q3IU31 Cluster: Probable dehydrogenase/ reductase 4; n=... 59 8e-08
UniRef50_A7DJ01 Cluster: Short-chain dehydrogenase/reductase SDR... 59 1e-07
UniRef50_Q20840 Cluster: Putative uncharacterized protein; n=2; ... 59 1e-07
UniRef50_Q6MRN8 Cluster: Putative oxidoreductase; n=1; Bdellovib... 58 1e-07
UniRef50_A3HAH4 Cluster: Short-chain dehydrogenase/reductase SDR... 58 1e-07
UniRef50_Q0S388 Cluster: Possible dehydrogenase; n=16; Corynebac... 58 2e-07
UniRef50_Q0RXI5 Cluster: Probable short-chain dehydrogenase; n=1... 58 2e-07
UniRef50_Q08T77 Cluster: Oxidoreductase; n=1; Stigmatella aurant... 58 2e-07
UniRef50_Q07WY7 Cluster: Short-chain dehydrogenase/reductase SDR... 58 2e-07
UniRef50_A3PSV4 Cluster: Short-chain dehydrogenase/reductase SDR... 58 2e-07
UniRef50_Q19246 Cluster: Dehydrogenases, short chain protein 25;... 58 2e-07
UniRef50_Q8TMH3 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 58 2e-07
UniRef50_A7D324 Cluster: Short-chain dehydrogenase/reductase SDR... 58 2e-07
UniRef50_Q07530 Cluster: Uncharacterized oxidoreductase YDL114W;... 58 2e-07
UniRef50_Q7D8X9 Cluster: Oxidoreductase, short-chain dehydrogena... 58 2e-07
UniRef50_Q1GI00 Cluster: Short-chain dehydrogenase/reductase SDR... 58 2e-07
UniRef50_A7HRS7 Cluster: Short-chain dehydrogenase/reductase SDR... 58 2e-07
UniRef50_Q9FJP5 Cluster: Similarity to dehydrogenase; n=9; core ... 58 2e-07
UniRef50_P80365 Cluster: Corticosteroid 11-beta-dehydrogenase is... 58 2e-07
UniRef50_Q4L7K1 Cluster: Similar to 3(or 17)beta-hydroxysteroid ... 57 3e-07
UniRef50_Q3WJ14 Cluster: Short-chain dehydrogenase/reductase SDR... 57 3e-07
UniRef50_Q1IPD7 Cluster: Short-chain dehydrogenase/reductase SDR... 57 3e-07
UniRef50_Q04HM4 Cluster: D-alanine transfer protein, short-chain... 57 3e-07
UniRef50_A5V342 Cluster: Short-chain dehydrogenase/reductase SDR... 57 3e-07
UniRef50_A5ICI0 Cluster: Oxidoreductase, short chain dehydrogena... 57 3e-07
UniRef50_A3YG01 Cluster: Short-chain dehydrogenase/reductase SDR... 57 3e-07
UniRef50_A1UD76 Cluster: Short-chain dehydrogenase/reductase SDR... 57 3e-07
UniRef50_A0QZW1 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 57 3e-07
UniRef50_Q1ITJ9 Cluster: Short-chain dehydrogenase/reductase SDR... 57 4e-07
UniRef50_A6G575 Cluster: Oxidoreductase, short chain dehydrogena... 57 4e-07
UniRef50_A5FD88 Cluster: Short-chain dehydrogenase/reductase SDR... 57 4e-07
UniRef50_P0AFP5 Cluster: Uncharacterized oxidoreductase ybbO; n=... 57 4e-07
UniRef50_P14061 Cluster: Estradiol 17-beta-dehydrogenase 1; n=38... 57 4e-07
UniRef50_Q81RT0 Cluster: Oxidoreductase, short-chain dehydrogena... 56 5e-07
UniRef50_Q5KRX7 Cluster: Putative oxidoreductase; n=2; Corynebac... 56 5e-07
UniRef50_A6EJ72 Cluster: Short-chain dehydrogenase; n=1; Pedobac... 56 5e-07
UniRef50_Q5BII6 Cluster: RH05486p; n=4; Sophophora|Rep: RH05486p... 56 5e-07
UniRef50_Q09851 Cluster: Uncharacterized oxidoreductase C23D3.11... 56 5e-07
UniRef50_Q7UIV9 Cluster: Ketoacyl reductase; n=1; Pirellula sp.|... 56 7e-07
UniRef50_Q41CM8 Cluster: Short-chain dehydrogenase/reductase SDR... 56 7e-07
UniRef50_Q1JYA3 Cluster: Short-chain dehydrogenase/reductase SDR... 56 7e-07
UniRef50_A5FF05 Cluster: Short-chain dehydrogenase/reductase SDR... 56 7e-07
UniRef50_A5CSQ5 Cluster: Short chain dehydrogenase/oxidoreductas... 56 7e-07
UniRef50_Q2U1R9 Cluster: Dehydrogenases with different specifici... 56 7e-07
UniRef50_Q89FM8 Cluster: Dehydrogenase; n=1; Bradyrhizobium japo... 56 1e-06
UniRef50_Q1CWB6 Cluster: Oxidoreductase, short chain dehydrogena... 56 1e-06
UniRef50_Q11QG7 Cluster: Short-chain alcohol-related dehydrogena... 56 1e-06
UniRef50_Q0S3V2 Cluster: Short chain dehydrogenase; n=4; Bacteri... 56 1e-06
UniRef50_A5ELU7 Cluster: Putative Short-chain dehydrogenase/redu... 56 1e-06
UniRef50_A3R4Q6 Cluster: Oxidoreductase; n=1; Streptomyces vitam... 56 1e-06
UniRef50_A3PV65 Cluster: Short-chain dehydrogenase/reductase SDR... 56 1e-06
UniRef50_A0GPK9 Cluster: Short-chain dehydrogenase/reductase SDR... 56 1e-06
UniRef50_Q38D51 Cluster: Short-chain dehydrogenase, putative; n=... 56 1e-06
UniRef50_Q7NIM9 Cluster: Gll2154 protein; n=2; Bacteria|Rep: Gll... 55 1e-06
UniRef50_Q1N3U9 Cluster: Short chain dehydrogenase; n=1; Oceanob... 55 1e-06
UniRef50_Q0LEN5 Cluster: Short-chain dehydrogenase/reductase SDR... 55 1e-06
UniRef50_A5L8A4 Cluster: Short-chain dehydrogenase/reductase SDR... 55 1e-06
UniRef50_A4ABL9 Cluster: Short-chain dehydrogenase/reductase SDR... 55 1e-06
UniRef50_A0Y8P7 Cluster: Short chain dehydrogenase; n=1; marine ... 55 1e-06
UniRef50_A5AAH5 Cluster: Catalytic activity: estradiol-17-beta +... 55 1e-06
UniRef50_UPI000058941E Cluster: PREDICTED: hypothetical protein;... 55 2e-06
UniRef50_Q9CC98 Cluster: Short chain alcohol dehydrogenase; n=36... 55 2e-06
UniRef50_O34782 Cluster: YvrD protein; n=3; Bacillus|Rep: YvrD p... 55 2e-06
UniRef50_A6UDX9 Cluster: Short-chain dehydrogenase/reductase SDR... 55 2e-06
UniRef50_A6GAH4 Cluster: Oxidoreductase, short chain dehydrogena... 55 2e-06
UniRef50_A6EHZ8 Cluster: Short-chain dehydrogenase/reductase SDR... 55 2e-06
UniRef50_A3HWV9 Cluster: Short chain oxidoreductase; n=1; Algori... 55 2e-06
UniRef50_A1UM02 Cluster: Short-chain dehydrogenase/reductase SDR... 55 2e-06
UniRef50_A0GHU7 Cluster: Short-chain dehydrogenase/reductase SDR... 55 2e-06
UniRef50_O97166 Cluster: 3-alpha-hydroxysteroid dehydrogenase-li... 55 2e-06
UniRef50_UPI0000E4A41A Cluster: PREDICTED: similar to Retinol de... 54 2e-06
UniRef50_Q89G53 Cluster: Bll6494 protein; n=13; Proteobacteria|R... 54 2e-06
UniRef50_Q2BDF6 Cluster: Putative uncharacterized protein; n=1; ... 54 2e-06
UniRef50_A4C4K9 Cluster: Short-chain alcohol dehydrogenase-like ... 54 2e-06
UniRef50_A4BUN6 Cluster: Short-chain dehydrogenase/reductase SDR... 54 2e-06
UniRef50_A4A4T0 Cluster: Short-chain dehydrogenase/reductase SDR... 54 2e-06
UniRef50_A1VQT6 Cluster: Short-chain dehydrogenase/reductase SDR... 54 2e-06
UniRef50_A1UG25 Cluster: Short-chain dehydrogenase/reductase SDR... 54 2e-06
UniRef50_A0BHQ0 Cluster: Chromosome undetermined scaffold_108, w... 54 2e-06
UniRef50_A2BJK2 Cluster: Short chain dehydrogenase; n=1; Hyperth... 54 2e-06
UniRef50_P37959 Cluster: Uncharacterized oxidoreductase yusZ; n=... 54 2e-06
UniRef50_UPI0000584AC8 Cluster: PREDICTED: similar to retinol de... 54 3e-06
UniRef50_Q9CBP7 Cluster: Possible short chain reductase; n=20; B... 54 3e-06
UniRef50_Q9A477 Cluster: Short chain dehydrogenase family protei... 54 3e-06
UniRef50_A1ZYN0 Cluster: Dehydrogenase/reductase SDR family memb... 54 3e-06
UniRef50_A0Z5T7 Cluster: 3-ketoacyl-(Acyl-carrier-protein) reduc... 54 3e-06
UniRef50_Q4A054 Cluster: Uncharacterized oxidoreductase SSP0419;... 54 3e-06
UniRef50_P66778 Cluster: Probable oxidoreductase ephD; n=16; Myc... 54 3e-06
UniRef50_UPI000058485A Cluster: PREDICTED: similar to retinol de... 54 4e-06
UniRef50_Q6PC70 Cluster: Retinol dehydrogenase 8; n=14; Euteleos... 54 4e-06
UniRef50_Q8ELB7 Cluster: Oxidoreductase; n=1; Oceanobacillus ihe... 54 4e-06
UniRef50_Q1GSP0 Cluster: Short-chain dehydrogenase/reductase SDR... 54 4e-06
UniRef50_Q0LKA9 Cluster: Short-chain dehydrogenase/reductase SDR... 54 4e-06
UniRef50_A5FZ99 Cluster: Short-chain dehydrogenase/reductase SDR... 54 4e-06
UniRef50_A4BRT2 Cluster: Probable oxidoreductase; n=1; Nitrococc... 54 4e-06
UniRef50_Q2QLP7 Cluster: Oxidoreductase, short chain dehydrogena... 54 4e-06
UniRef50_A7RGK5 Cluster: Predicted protein; n=4; Eumetazoa|Rep: ... 54 4e-06
UniRef50_Q9Y8Y1 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 54 4e-06
UniRef50_UPI0000E4927A Cluster: PREDICTED: similar to retinol de... 53 5e-06
UniRef50_UPI000038D7DD Cluster: COG1028: Dehydrogenases with dif... 53 5e-06
UniRef50_Q4K8K3 Cluster: Oxidoreductase, short chain dehydrogena... 53 5e-06
UniRef50_Q2IK95 Cluster: Short-chain dehydrogenase/reductase SDR... 53 5e-06
UniRef50_Q28P30 Cluster: Short-chain dehydrogenase/reductase SDR... 53 5e-06
UniRef50_Q15UE4 Cluster: 3-hydroxybutyrate dehydrogenase precurs... 53 5e-06
UniRef50_Q0FWE7 Cluster: Short-chain alcohol dehydrogenase; n=2;... 53 5e-06
UniRef50_A7GTG0 Cluster: Amino acid adenylation domain; n=2; Fir... 53 5e-06
UniRef50_A6UFZ1 Cluster: Short-chain dehydrogenase/reductase SDR... 53 5e-06
UniRef50_A5UVY6 Cluster: Short-chain dehydrogenase/reductase SDR... 53 5e-06
UniRef50_A4BV46 Cluster: Putative ketoreductase; n=1; Nitrococcu... 53 5e-06
UniRef50_A3VG77 Cluster: Short-chain dehydrogenase/reductase SDR... 53 5e-06
UniRef50_A1UGA6 Cluster: Short-chain dehydrogenase/reductase SDR... 53 5e-06
UniRef50_A0Z6U9 Cluster: Short-chain dehydrogenase/reductase SDR... 53 5e-06
UniRef50_A3LZX3 Cluster: 1-acyl dihydroxyacetone phosphate reduc... 53 5e-06
UniRef50_Q82Q22 Cluster: Putative dehydrogenase; n=4; Streptomyc... 53 7e-06
UniRef50_Q6D7W8 Cluster: Probable short chain dehydrogenase; n=1... 53 7e-06
UniRef50_Q3KCP9 Cluster: Short-chain dehydrogenase/reductase SDR... 53 7e-06
UniRef50_Q390V2 Cluster: Short-chain dehydrogenase/reductase SDR... 53 7e-06
UniRef50_Q02B17 Cluster: Short-chain dehydrogenase/reductase SDR... 53 7e-06
UniRef50_A7IE62 Cluster: Short-chain dehydrogenase/reductase SDR... 53 7e-06
UniRef50_A7H6A6 Cluster: Short-chain dehydrogenase/reductase SDR... 53 7e-06
UniRef50_A4XF79 Cluster: Short-chain dehydrogenase/reductase SDR... 53 7e-06
UniRef50_Q872E5 Cluster: Putative uncharacterized protein 80A10.... 53 7e-06
UniRef50_Q8R9W0 Cluster: Dehydrogenases with different specifici... 52 9e-06
UniRef50_Q8EQ60 Cluster: Oxidoreductase; n=1; Oceanobacillus ihe... 52 9e-06
UniRef50_Q5NM60 Cluster: Short-chain alcohol dehydrogenase; n=14... 52 9e-06
UniRef50_Q5KZB7 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 52 9e-06
UniRef50_Q2S401 Cluster: Oxidoreductase, short chain dehydrogena... 52 9e-06
UniRef50_Q1N298 Cluster: Short chain dehydrogenase; n=1; Oceanob... 52 9e-06
UniRef50_Q1DCG1 Cluster: Oxidoreductase, short-chain dehydrogena... 52 9e-06
UniRef50_A3ZTM1 Cluster: Probable short-chain dehydrogenase; n=1... 52 9e-06
UniRef50_A3JFT9 Cluster: Short chain dehydrogenase; n=1; Marinob... 52 9e-06
UniRef50_A2SJ81 Cluster: Oxidoreductase, short-chain dehydrogena... 52 9e-06
UniRef50_A1G528 Cluster: Short-chain dehydrogenase/reductase SDR... 52 9e-06
UniRef50_A0Z215 Cluster: Short chain dehydrogenase; n=2; Gammapr... 52 9e-06
UniRef50_A0M1K4 Cluster: Short-chain dehydrogenase/reductase fam... 52 9e-06
UniRef50_Q7XZ53 Cluster: Short-chain alcohol dehydrogenase famil... 52 9e-06
UniRef50_Q7SHI2 Cluster: Putative uncharacterized protein NCU029... 52 9e-06
UniRef50_Q5KC11 Cluster: Ketoreductase, putative; n=1; Filobasid... 52 9e-06
UniRef50_UPI000038DA04 Cluster: COG1028: Dehydrogenases with dif... 52 1e-05
UniRef50_Q1LWF3 Cluster: Novel protein; n=9; Euteleostomi|Rep: N... 52 1e-05
UniRef50_Q46241 Cluster: NanH gene & ORF1,2,3 & 4 precursor; n=4... 52 1e-05
UniRef50_Q1ZIG4 Cluster: Putative short-chain dehydrogenase; n=1... 52 1e-05
UniRef50_Q02BL8 Cluster: Short-chain dehydrogenase/reductase SDR... 52 1e-05
UniRef50_A5WY75 Cluster: Orf_Bo159; n=22; Bacteria|Rep: Orf_Bo15... 52 1e-05
UniRef50_A4XEF9 Cluster: Short-chain dehydrogenase/reductase SDR... 52 1e-05
UniRef50_A1UPA3 Cluster: Short-chain dehydrogenase/reductase SDR... 52 1e-05
UniRef50_A1IB88 Cluster: Oxidoreductase, short chain dehydrogena... 52 1e-05
UniRef50_A0QN52 Cluster: DltE protein; n=1; Mycobacterium avium ... 52 1e-05
UniRef50_A0PUC7 Cluster: Dehydrogenase/decarboxylase protein; n=... 52 1e-05
UniRef50_Q61YR4 Cluster: Putative uncharacterized protein CBG034... 52 1e-05
UniRef50_Q9HSR4 Cluster: Oxidoreductase; n=6; cellular organisms... 52 1e-05
UniRef50_UPI0000E49D04 Cluster: PREDICTED: hypothetical protein,... 52 2e-05
UniRef50_Q87XV8 Cluster: Oxidoreductase, short-chain dehydrogena... 52 2e-05
UniRef50_Q6D5Y3 Cluster: Short chain dehydrogenase; n=5; Proteob... 52 2e-05
UniRef50_Q3BTU5 Cluster: Short chain dehydrogenase; n=1; Xanthom... 52 2e-05
UniRef50_Q2B357 Cluster: Oxidoreductase, short chain dehydrogena... 52 2e-05
UniRef50_A1ZL47 Cluster: Oxidoreductase, short chain dehydrogena... 52 2e-05
UniRef50_A0H5N7 Cluster: Short-chain dehydrogenase/reductase SDR... 52 2e-05
UniRef50_Q9W5H1 Cluster: CG13377-PA; n=5; Diptera|Rep: CG13377-P... 52 2e-05
UniRef50_Q54WM6 Cluster: Putative uncharacterized protein; n=2; ... 52 2e-05
UniRef50_A2QJV4 Cluster: Contig An04c0270, complete genome. prec... 52 2e-05
UniRef50_Q5UYV4 Cluster: Oxidoreductase; n=1; Haloarcula marismo... 52 2e-05
UniRef50_UPI00015549FC Cluster: PREDICTED: similar to 3-hydroxyb... 51 2e-05
UniRef50_Q9A3M7 Cluster: Short chain dehydrogenase family protei... 51 2e-05
UniRef50_Q2GBS3 Cluster: Short-chain dehydrogenase/reductase SDR... 51 2e-05
UniRef50_Q2AV34 Cluster: Short-chain dehydrogenase/reductase SDR... 51 2e-05
UniRef50_Q1MZC9 Cluster: Oxidoreductase, short-chain dehydrogena... 51 2e-05
UniRef50_Q0LMZ4 Cluster: Short-chain dehydrogenase/reductase SDR... 51 2e-05
UniRef50_A3U7Y8 Cluster: Oxidoreductase; n=2; Flavobacteriaceae|... 51 2e-05
UniRef50_Q4D5D5 Cluster: Short chain dehydrogenase, putative; n=... 51 2e-05
UniRef50_Q16FA9 Cluster: Short-chain dehydrogenase; n=1; Aedes a... 51 2e-05
UniRef50_Q97WD7 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct... 51 2e-05
UniRef50_A0RXB6 Cluster: Short-chain alcohol dehydrogenase; n=2;... 51 2e-05
UniRef50_P14802 Cluster: Uncharacterized oxidoreductase yoxD; n=... 51 2e-05
UniRef50_Q985G9 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct... 51 3e-05
UniRef50_Q8A945 Cluster: Putative oxidoreductase; n=3; Bacteroid... 51 3e-05
UniRef50_Q8RTR1 Cluster: Alcohol dehydrogenase; n=69; Proteobact... 51 3e-05
UniRef50_Q3WB10 Cluster: Short-chain dehydrogenase/reductase SDR... 51 3e-05
UniRef50_Q28RW9 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct... 51 3e-05
UniRef50_Q026V2 Cluster: Short-chain dehydrogenase/reductase SDR... 51 3e-05
UniRef50_A6QK68 Cluster: Oxidoreductase; n=12; Staphylococcus au... 51 3e-05
UniRef50_A6CNE9 Cluster: Cyclohexanol dehydrogenase; n=3; Bacill... 51 3e-05
UniRef50_A5VEH5 Cluster: Short-chain dehydrogenase/reductase SDR... 51 3e-05
UniRef50_A5GNL7 Cluster: Short-chain dehydrogenase/reductase fam... 51 3e-05
UniRef50_A4X6Z1 Cluster: Short-chain dehydrogenase/reductase SDR... 51 3e-05
UniRef50_A3JK09 Cluster: Oxidoreductase; n=1; Marinobacter sp. E... 51 3e-05
UniRef50_A0M1Z5 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 51 3e-05
UniRef50_A7S0P8 Cluster: Predicted protein; n=2; Nematostella ve... 51 3e-05
UniRef50_UPI00015B49F3 Cluster: PREDICTED: similar to oxidoreduc... 50 4e-05
UniRef50_UPI0000ECB73B Cluster: 11-cis retinol dehydrogenase (EC... 50 4e-05
UniRef50_Q5E6R7 Cluster: Short chain dehydrogenase; n=3; Gammapr... 50 4e-05
UniRef50_Q2JY74 Cluster: Oxidoreductase, short chain dehydrogena... 50 4e-05
UniRef50_Q1DFC5 Cluster: Oxidoreductase, short chain dehydrogena... 50 4e-05
UniRef50_Q0S4U3 Cluster: Dehydrogenase; n=2; Actinomycetales|Rep... 50 4e-05
UniRef50_A7MMI9 Cluster: Putative uncharacterized protein; n=1; ... 50 4e-05
UniRef50_A6C0A9 Cluster: Short-chain dehydrogenase/reductase SDR... 50 4e-05
UniRef50_A3J2Q4 Cluster: Short-chain dehydrogenase; n=2; Flavoba... 50 4e-05
UniRef50_A0M3M9 Cluster: Short-chain dehydrogenase/reductase fam... 50 4e-05
UniRef50_Q01JQ2 Cluster: H0523F07.11 protein; n=4; Oryza sativa|... 50 4e-05
UniRef50_A7R1I3 Cluster: Chromosome undetermined scaffold_358, w... 50 4e-05
UniRef50_A6R0Z3 Cluster: Predicted protein; n=1; Ajellomyces cap... 50 4e-05
UniRef50_A2R6G5 Cluster: Contig An15c0250, complete genome; n=1;... 50 4e-05
UniRef50_Q9NYR8 Cluster: Retinol dehydrogenase 8; n=24; Euteleos... 50 4e-05
UniRef50_Q04520 Cluster: Acetoin(diacetyl) reductase; n=1; Raoul... 50 4e-05
UniRef50_UPI0000510098 Cluster: COG1028: Dehydrogenases with dif... 50 5e-05
UniRef50_Q737G7 Cluster: Short chain dehydrogenase family protei... 50 5e-05
UniRef50_Q2K6U1 Cluster: Probable oxidoreductase protein; n=2; P... 50 5e-05
UniRef50_A7DM41 Cluster: Short-chain dehydrogenase/reductase SDR... 50 5e-05
UniRef50_A6W2Y5 Cluster: Short-chain dehydrogenase/reductase SDR... 50 5e-05
UniRef50_A5V305 Cluster: Short-chain dehydrogenase/reductase SDR... 50 5e-05
UniRef50_A3K7F0 Cluster: Putative oxidoreductase protein; n=1; S... 50 5e-05
UniRef50_A1ZM53 Cluster: Short chain dehydrogenase; n=1; Microsc... 50 5e-05
UniRef50_A1W2D9 Cluster: Short-chain dehydrogenase/reductase SDR... 50 5e-05
UniRef50_A0JXQ7 Cluster: Short-chain dehydrogenase/reductase SDR... 50 5e-05
UniRef50_A0JAB3 Cluster: Short-chain dehydrogenase/reductase SDR... 50 5e-05
UniRef50_Q16M72 Cluster: Hydroxybutyrate dehydrogenase; n=4; End... 50 5e-05
UniRef50_A7RNX1 Cluster: Predicted protein; n=1; Nematostella ve... 50 5e-05
UniRef50_Q2FSZ0 Cluster: Short-chain dehydrogenase/reductase SDR... 50 5e-05
UniRef50_Q06136 Cluster: 3-ketodihydrosphingosine reductase prec... 50 5e-05
UniRef50_Q9S1Q4 Cluster: Putative oxidoreductase; n=2; Streptomy... 50 6e-05
UniRef50_Q9RKB7 Cluster: Probable 3-oxoacyl-[acyl carrier protei... 50 6e-05
UniRef50_Q98JK8 Cluster: Oxidoreductase of short-chain; n=8; Pro... 50 6e-05
UniRef50_Q89DU5 Cluster: Blr7343 protein; n=3; Bradyrhizobium|Re... 50 6e-05
UniRef50_Q83D17 Cluster: Oxidoreductase, short-chain dehydrogena... 50 6e-05
UniRef50_Q67RV7 Cluster: Putative oxidoreductase; n=1; Symbiobac... 50 6e-05
UniRef50_Q48LL4 Cluster: Oxidoreductase, short-chain dehydrogena... 50 6e-05
UniRef50_Q2IEG2 Cluster: Short-chain dehydrogenase/reductase SDR... 50 6e-05
UniRef50_Q1IKU0 Cluster: Short-chain dehydrogenase/reductase SDR... 50 6e-05
UniRef50_Q1DDT9 Cluster: Oxidoreductase, short chain dehydrogena... 50 6e-05
UniRef50_Q0YP41 Cluster: Short-chain dehydrogenase/reductase SDR... 50 6e-05
UniRef50_Q026V0 Cluster: Short-chain dehydrogenase/reductase SDR... 50 6e-05
UniRef50_A3EPN7 Cluster: Putative short-chain alcohol dehydrogen... 50 6e-05
UniRef50_A7QX66 Cluster: Chromosome undetermined scaffold_213, w... 50 6e-05
UniRef50_Q5HKG6 Cluster: Acetoin(diacetyl) reductase; n=6; Bacte... 50 6e-05
UniRef50_A1ZK52 Cluster: Dehydrogenase/reductase SDR family memb... 48 7e-05
UniRef50_UPI0000E47E8E Cluster: PREDICTED: similar to Retinol de... 49 8e-05
UniRef50_UPI000023E40F Cluster: hypothetical protein FG03579.1; ... 49 8e-05
UniRef50_Q87GW0 Cluster: Acetoacetyl-CoA reductase; n=7; Vibrio|... 49 8e-05
UniRef50_Q5FKH2 Cluster: Oxidoreductase, short chaindehydrogenas... 49 8e-05
UniRef50_Q2S7V4 Cluster: Short-chain alcohol dehydrogenase-like ... 49 8e-05
UniRef50_Q10782 Cluster: Possible ketoacyl reductase; n=11; Myco... 49 8e-05
UniRef50_Q8RTU4 Cluster: Short chain dehydrogenase family protei... 49 8e-05
UniRef50_Q15NJ3 Cluster: Short-chain dehydrogenase/reductase SDR... 49 8e-05
UniRef50_Q0VMP1 Cluster: Short chain dehydrogenase/reductase, pu... 49 8e-05
UniRef50_Q0M3P6 Cluster: NAD-dependent epimerase/dehydratase:Sho... 49 8e-05
UniRef50_Q0K3J3 Cluster: Short chain dehydrogenase; n=2; Cupriav... 49 8e-05
UniRef50_Q0C499 Cluster: Oxidoreductase, short chain dehydrogena... 49 8e-05
UniRef50_A6ECJ3 Cluster: Short chain dehydrogenase; n=1; Pedobac... 49 8e-05
UniRef50_A6E7M9 Cluster: Short-chain dehydrogenase/reductase SDR... 49 8e-05
UniRef50_A6C1B7 Cluster: Putative uncharacterized protein; n=1; ... 49 8e-05
UniRef50_A1U9F9 Cluster: Short-chain dehydrogenase/reductase SDR... 49 8e-05
UniRef50_Q8SYA6 Cluster: RH08058p; n=5; Diptera|Rep: RH08058p - ... 49 8e-05
UniRef50_Q54HS2 Cluster: Putative uncharacterized protein; n=1; ... 49 8e-05
UniRef50_Q2H7T1 Cluster: Putative uncharacterized protein; n=1; ... 49 8e-05
UniRef50_Q0UEA1 Cluster: Putative uncharacterized protein; n=1; ... 49 8e-05
UniRef50_A2R9D0 Cluster: Remark: during fruiting body developmen... 49 8e-05
UniRef50_Q10245 Cluster: Uncharacterized oxidoreductase C4G9.15;... 49 8e-05
UniRef50_P25970 Cluster: Uncharacterized oxidoreductase MXAN_590... 49 8e-05
UniRef50_Q97NV2 Cluster: Oxidoreductase, short chain dehydrogena... 49 1e-04
UniRef50_Q3IVH5 Cluster: Short-chain dehydrogenase/reductase SDR... 49 1e-04
UniRef50_Q39ME1 Cluster: Short-chain dehydrogenase/reductase SDR... 49 1e-04
UniRef50_Q0FK49 Cluster: FabG3_1; n=1; Roseovarius sp. HTCC2601|... 49 1e-04
UniRef50_Q0F2B4 Cluster: Short chain dehydrogenase; n=2; Proteob... 49 1e-04
UniRef50_A6W3U8 Cluster: Short-chain dehydrogenase/reductase SDR... 49 1e-04
UniRef50_A5USZ9 Cluster: Short-chain dehydrogenase/reductase SDR... 49 1e-04
UniRef50_A4X7G9 Cluster: Short-chain dehydrogenase/reductase SDR... 49 1e-04
UniRef50_A1ZEB0 Cluster: Possible ketoacyl reductase; n=1; Micro... 49 1e-04
UniRef50_A0YDH9 Cluster: Putative oxidoreductase; n=1; marine ga... 49 1e-04
UniRef50_A0J9W6 Cluster: Short-chain dehydrogenase/reductase SDR... 49 1e-04
UniRef50_Q16HM8 Cluster: Putative uncharacterized protein; n=1; ... 49 1e-04
UniRef50_Q4P1X0 Cluster: Putative uncharacterized protein; n=1; ... 49 1e-04
UniRef50_Q5V3M2 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 49 1e-04
UniRef50_Q48436 Cluster: Acetoin(diacetyl) reductase; n=59; cell... 49 1e-04
UniRef50_UPI0000E4700A Cluster: PREDICTED: hypothetical protein,... 48 1e-04
UniRef50_UPI000050F7E5 Cluster: COG1028: Dehydrogenases with dif... 48 1e-04
UniRef50_Q8YSW6 Cluster: Oxidoreductase; n=3; Nostocaceae|Rep: O... 48 1e-04
UniRef50_Q8EN17 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=20; ... 48 1e-04
UniRef50_Q815Q8 Cluster: Short chain dehydrogenase; n=1; Bacillu... 48 1e-04
UniRef50_Q398N9 Cluster: Short-chain dehydrogenase/reductase SDR... 48 1e-04
UniRef50_Q7CW28 Cluster: AGR_L_43p; n=4; Proteobacteria|Rep: AGR... 48 1e-04
UniRef50_Q6HXT9 Cluster: Oxidoreductase, short-chain dehydrogena... 48 1e-04
UniRef50_Q3W5I4 Cluster: Short-chain dehydrogenase/reductase SDR... 48 1e-04
UniRef50_Q2AGJ3 Cluster: NAD-dependent epimerase/dehydratase:Sho... 48 1e-04
UniRef50_Q21Z23 Cluster: Short-chain dehydrogenase/reductase SDR... 48 1e-04
UniRef50_Q13XG5 Cluster: Putative short-chain dehydrogenase/redu... 48 1e-04
UniRef50_Q022W9 Cluster: Short-chain dehydrogenase/reductase SDR... 48 1e-04
UniRef50_A6VPT1 Cluster: Short-chain dehydrogenase/reductase SDR... 48 1e-04
UniRef50_A4XF86 Cluster: Short-chain dehydrogenase/reductase SDR... 48 1e-04
UniRef50_A3ZWB3 Cluster: 1-cyclohexenylcarbonyl CoA reductase-sh... 48 1e-04
UniRef50_A1ZIV8 Cluster: Short-chain dehydrogenase/reductase SDR... 48 1e-04
UniRef50_A1U9A7 Cluster: Short-chain dehydrogenase/reductase SDR... 48 1e-04
UniRef50_A0YGB7 Cluster: Probable short-chain dehydrogenase; n=1... 48 1e-04
UniRef50_Q8IGG7 Cluster: RH24570p; n=37; Eumetazoa|Rep: RH24570p... 48 1e-04
UniRef50_Q7QV57 Cluster: GLP_435_8600_7644; n=1; Giardia lamblia... 48 1e-04
UniRef50_O74959 Cluster: Short chain dehydrogenase; n=1; Schizos... 48 1e-04
UniRef50_A2QFQ6 Cluster: Contig An03c0020, complete genome; n=4;... 48 1e-04
UniRef50_P40471 Cluster: NADPH-dependent 1-acyldihydroxyacetone ... 48 1e-04
UniRef50_Q9S0N7 Cluster: C-5 ketoreductase; n=3; Bacteria|Rep: C... 48 2e-04
UniRef50_Q8UAB0 Cluster: Dehydrogenase; n=1; Agrobacterium tumef... 48 2e-04
UniRef50_Q8KKW7 Cluster: Probable oxidoreductase protein; n=2; P... 48 2e-04
UniRef50_Q7P820 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 48 2e-04
UniRef50_Q1GS40 Cluster: Short-chain dehydrogenase/reductase SDR... 48 2e-04
UniRef50_Q0SHW8 Cluster: Probable short-chain dehydrogenase; n=1... 48 2e-04
UniRef50_A6EA39 Cluster: Short-chain dehydrogenase; n=1; Pedobac... 48 2e-04
UniRef50_A1ZGN7 Cluster: Short-chain dehydrogenase/reductase SDR... 48 2e-04
UniRef50_A1UHZ5 Cluster: Short-chain dehydrogenase/reductase SDR... 48 2e-04
UniRef50_Q9VJG8 Cluster: CG6012-PA; n=2; Sophophora|Rep: CG6012-... 48 2e-04
UniRef50_Q5AUZ8 Cluster: Putative uncharacterized protein; n=1; ... 48 2e-04
UniRef50_Q0CEC6 Cluster: Predicted protein; n=1; Aspergillus ter... 48 2e-04
UniRef50_A2R6T6 Cluster: Contig An16c0040, complete genome; n=3;... 48 2e-04
UniRef50_Q5V473 Cluster: Short-chain dehydrogenase/oxidoreductas... 48 2e-04
UniRef50_Q4RVG4 Cluster: Chromosome 15 SCAF14992, whole genome s... 48 3e-04
UniRef50_Q9WYS2 Cluster: Oxidoreductase, short chain dehydrogena... 48 3e-04
UniRef50_Q8YZV3 Cluster: NADPH-dependent carbonyl reductase; n=5... 48 3e-04
UniRef50_Q88ZF7 Cluster: Short-chain dehydrogenase/oxidoreductas... 48 3e-04
UniRef50_Q3J0A0 Cluster: Putative 3-oxoacyl-(Acyl-carrier-protei... 48 3e-04
UniRef50_Q39LN3 Cluster: Short-chain dehydrogenase/reductase SDR... 48 3e-04
UniRef50_Q0SDB4 Cluster: Short chain dehydrogenase; n=1; Rhodoco... 48 3e-04
UniRef50_Q0RTK3 Cluster: Putative Short-chain dehydrogenase/redu... 48 3e-04
UniRef50_Q0RJN1 Cluster: Putative short chain oxidoreductase; n=... 48 3e-04
UniRef50_A6WBU5 Cluster: Short-chain dehydrogenase/reductase SDR... 48 3e-04
UniRef50_A6GC41 Cluster: Short-chain dehydrogenase/reductase SDR... 48 3e-04
UniRef50_A6G9L1 Cluster: Oxidoreductase, short chain dehydrogena... 48 3e-04
UniRef50_A4EYN4 Cluster: Putative uncharacterized protein; n=2; ... 48 3e-04
UniRef50_A0PSR4 Cluster: Short-chain dehydrogenase; n=1; Mycobac... 48 3e-04
UniRef50_A7F3T6 Cluster: Putative uncharacterized protein; n=1; ... 48 3e-04
UniRef50_UPI00015B54B8 Cluster: PREDICTED: similar to oxidoreduc... 47 3e-04
UniRef50_UPI000045C012 Cluster: COG1028: Dehydrogenases with dif... 47 3e-04
UniRef50_Q9RT26 Cluster: 3-oxoacyl-acyl carrier protein reductas... 47 3e-04
UniRef50_Q89ML0 Cluster: Blr4183 protein; n=16; Bacteria|Rep: Bl... 47 3e-04
UniRef50_Q5P5I4 Cluster: (S)-1-Phenylethanol dehydrogenase; n=1;... 47 3e-04
UniRef50_Q5NZC3 Cluster: Predicted short chain dehydrogenase; n=... 47 3e-04
UniRef50_Q2RWG2 Cluster: Short-chain dehydrogenase/reductase SDR... 47 3e-04
UniRef50_Q2JF82 Cluster: Short-chain dehydrogenase/reductase SDR... 47 3e-04
UniRef50_Q41G38 Cluster: Short-chain dehydrogenase/reductase SDR... 47 3e-04
UniRef50_Q2CKD4 Cluster: Short-chain dehydrogenase/reductase fam... 47 3e-04
UniRef50_Q12B22 Cluster: Short-chain dehydrogenase/reductase SDR... 47 3e-04
UniRef50_A6W9E2 Cluster: Short-chain dehydrogenase/reductase SDR... 47 3e-04
UniRef50_A6E9L8 Cluster: Putative uncharacterized protein; n=1; ... 47 3e-04
UniRef50_A6CTS3 Cluster: Putative uncharacterized protein; n=1; ... 47 3e-04
UniRef50_A5UWJ6 Cluster: Short-chain dehydrogenase/reductase SDR... 47 3e-04
UniRef50_A3ZUW7 Cluster: Putative oxidoreductase; n=1; Blastopir... 47 3e-04
UniRef50_A1U9Z1 Cluster: Short-chain dehydrogenase/reductase SDR... 47 3e-04
UniRef50_A0QXW7 Cluster: Short-chain dehydrogenase/reductase; n=... 47 3e-04
UniRef50_O74628 Cluster: Short chain dehydrogenase; n=1; Schizos... 47 3e-04
UniRef50_A7TJI6 Cluster: Putative uncharacterized protein; n=1; ... 47 3e-04
UniRef50_Q8N3Y7 Cluster: Epidermal retinal dehydrogenase 2; n=36... 47 3e-04
UniRef50_Q8GAV9 Cluster: Cyclopentanol dehydrogenase; n=9; Bacte... 47 3e-04
UniRef50_O86034 Cluster: D-beta-hydroxybutyrate dehydrogenase; n... 47 3e-04
UniRef50_UPI00015B5CBB Cluster: PREDICTED: similar to ENSANGP000... 47 4e-04
UniRef50_UPI0000D57363 Cluster: PREDICTED: similar to hydroxypro... 47 4e-04
UniRef50_Q9AK65 Cluster: Putative glucose 1-dehydrogenase; n=2; ... 47 4e-04
UniRef50_Q8PPZ3 Cluster: Oxidoreductase; n=2; Proteobacteria|Rep... 47 4e-04
UniRef50_Q8KG22 Cluster: Oxidoreductase, short-chain dehydrogena... 47 4e-04
UniRef50_Q8E9X1 Cluster: Oxidoreductase, short-chain dehydrogena... 47 4e-04
UniRef50_Q88T73 Cluster: Short-chain dehydrogenase/oxidoreductas... 47 4e-04
UniRef50_Q81M93 Cluster: Oxidoreductase, short-chain dehydrogena... 47 4e-04
UniRef50_Q7UJY8 Cluster: Probable short-chain dehydrogenase; n=1... 47 4e-04
UniRef50_Q5WE81 Cluster: Short-chain dehydrogenase; n=1; Bacillu... 47 4e-04
UniRef50_Q48I17 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct... 47 4e-04
UniRef50_A4ARP0 Cluster: Putative short chain oxidoreductase pro... 47 4e-04
UniRef50_A3HWW0 Cluster: Short-chain dehydrogenase; n=1; Algorip... 47 4e-04
UniRef50_A1G626 Cluster: Short-chain dehydrogenase/reductase SDR... 47 4e-04
UniRef50_Q9VCS2 Cluster: CG13833-PA; n=2; Sophophora|Rep: CG1383... 47 4e-04
UniRef50_Q22R68 Cluster: Oxidoreductase, short chain dehydrogena... 47 4e-04
UniRef50_Q2UUQ7 Cluster: Dehydrogenases with different specifici... 47 4e-04
UniRef50_UPI0000E47E5A Cluster: PREDICTED: hypothetical protein;... 46 6e-04
UniRef50_Q9CEQ0 Cluster: 3-oxoacyl-acyl carrier protein reductas... 46 6e-04
UniRef50_Q8YT35 Cluster: All2891 protein; n=8; Cyanobacteria|Rep... 46 6e-04
UniRef50_Q8YQ25 Cluster: Alr4011 protein; n=3; Bacteria|Rep: Alr... 46 6e-04
UniRef50_Q8YLL2 Cluster: Alr5286 protein; n=10; Cyanobacteria|Re... 46 6e-04
UniRef50_Q89X14 Cluster: Hypothetical oxidoreductase; n=3; Brady... 46 6e-04
UniRef50_Q6MLJ7 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct... 46 6e-04
UniRef50_Q6F7B8 Cluster: Fatty acyl-CoA reductase; n=6; Moraxell... 46 6e-04
UniRef50_Q2S467 Cluster: NAD-binding domain 4, putative; n=1; Sa... 46 6e-04
UniRef50_Q0SC53 Cluster: Dehydrogenase; n=3; Corynebacterineae|R... 46 6e-04
UniRef50_Q1R0D3 Cluster: Short-chain dehydrogenase/reductase SDR... 46 6e-04
UniRef50_Q0SE96 Cluster: Possible 3-oxoacyl-[acyl-carrier-protei... 46 6e-04
UniRef50_A4XEW8 Cluster: Short-chain dehydrogenase/reductase SDR... 46 6e-04
UniRef50_A4TJR6 Cluster: Dehydrogenase precursor; n=7; Yersinia|... 46 6e-04
UniRef50_A4SJZ3 Cluster: Oxidoreductase, short-chain dehydrogena... 46 6e-04
UniRef50_A4B8L3 Cluster: Short chain dehydrogenase; n=1; Alterom... 46 6e-04
UniRef50_A1UAJ6 Cluster: Acetoin reductases; n=18; Bacteria|Rep:... 46 6e-04
UniRef50_A1U1W7 Cluster: Short-chain dehydrogenase/reductase SDR... 46 6e-04
UniRef50_A1I967 Cluster: Ketoacyl reductases-like; n=1; Candidat... 46 6e-04
UniRef50_Q54Q00 Cluster: Putative uncharacterized protein; n=7; ... 46 6e-04
UniRef50_Q19843 Cluster: Dehydrogenases, short chain protein 29;... 46 6e-04
UniRef50_Q6MY99 Cluster: Short-chain oxidoreductase, putative; n... 46 6e-04
UniRef50_Q6CNU5 Cluster: Similar to sp|Q9ALU7 Enterobacter cloac... 46 6e-04
UniRef50_A5DPQ3 Cluster: Putative uncharacterized protein; n=2; ... 46 6e-04
UniRef50_A1DKR3 Cluster: Short chain dehydrogenase/reductase fam... 46 6e-04
UniRef50_UPI0000E0FECB Cluster: putative short-chain dehydrogena... 46 8e-04
UniRef50_UPI000023E2AD Cluster: hypothetical protein FG00054.1; ... 46 8e-04
UniRef50_Q9I216 Cluster: Probable short-chain dehydrogenase; n=6... 46 8e-04
UniRef50_Q8UH21 Cluster: Oxidoreductase; n=6; Bacteria|Rep: Oxid... 46 8e-04
UniRef50_Q1AT94 Cluster: Short-chain dehydrogenase/reductase SDR... 46 8e-04
UniRef50_Q15XF6 Cluster: Short-chain dehydrogenase/reductase SDR... 46 8e-04
UniRef50_Q124X5 Cluster: Male sterility-like; n=9; Proteobacteri... 46 8e-04
UniRef50_Q0SGM5 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct... 46 8e-04
UniRef50_Q0SFE0 Cluster: Probable short chain dehydrogenase; n=1... 46 8e-04
UniRef50_Q0S716 Cluster: Short chain dehydrogenase; n=3; Bacteri... 46 8e-04
UniRef50_A7HKF3 Cluster: Short-chain dehydrogenase/reductase SDR... 46 8e-04
UniRef50_A6ULH8 Cluster: Short-chain dehydrogenase/reductase SDR... 46 8e-04
>UniRef50_UPI00015B5DA8 Cluster: PREDICTED: similar to CG12068-PA;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
CG12068-PA - Nasonia vitripennis
Length = 331
Score = 124 bits (299), Expect = 2e-27
Identities = 71/169 (42%), Positives = 99/169 (58%)
Frame = +1
Query: 106 SAMSVSRLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLD 285
S + L+ +TGCDSGLG+++A +G +AG+ + ++EAA +L K A PLD
Sbjct: 33 SRLGPRHLIVLTGCDSGLGYSLACHCLCQGAKVVAGVLQE-KSEAADSLVKSGATVLPLD 91
Query: 286 VTRVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGA 465
+T SV+ F + V + K + +F A+VNNAGVM G++EW A + S + VN+LG
Sbjct: 92 LTDDSSVERFGREVEKISKTEDR-EFRALVNNAGVMIFGEFEWQLADQVRSQLEVNVLGT 150
Query: 466 MRVISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKS 612
M + LP IR + K RIINV SHC L PLP AAY ASK+
Sbjct: 151 MSLTKRLLPWIR--------EGKSRIINVTSHCALAPLPGLAAYGASKA 191
>UniRef50_UPI0000D5679E Cluster: PREDICTED: similar to CG12068-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG12068-PA - Tribolium castaneum
Length = 371
Score = 124 bits (298), Expect = 2e-27
Identities = 67/168 (39%), Positives = 98/168 (58%), Gaps = 2/168 (1%)
Frame = +1
Query: 115 SVSRLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHT--FPLDV 288
S+ ++V ++GCDSGLG+++A AR GF +AG +E+ A+ +++ LDV
Sbjct: 70 SLKQIVLISGCDSGLGFSLAIHAARLGFTVVAGF-LDLESPGAREIKQFHRKITQIQLDV 128
Query: 289 TRVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAM 468
T ESV + + L NP Y+F+A+VNNAGVM G++EW T +I VHVNL+G M
Sbjct: 129 TSKESVFVAVETINQYLNSNPSYEFYALVNNAGVMVFGEFEWQTERLIHQQVHVNLMGTM 188
Query: 469 RVISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKS 612
V AF+P +RK R+IN+ SHC LP + Y A+K+
Sbjct: 189 NVSRAFIPLLRKY--------HGRLINITSHCSFTCLPGLSVYGATKA 228
>UniRef50_UPI0000DB702A Cluster: PREDICTED: similar to CG12068-PA;
n=2; Apis mellifera|Rep: PREDICTED: similar to
CG12068-PA - Apis mellifera
Length = 302
Score = 118 bits (284), Expect = 1e-25
Identities = 63/161 (39%), Positives = 92/161 (57%)
Frame = +1
Query: 130 VAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESVQ 309
+ VTGCDSGLG+++A + G + IA + + I+ AK LE +PLDVT+++SV+
Sbjct: 27 IIVTGCDSGLGYSLALHCRKLGAVVIASVLQ-IDGPGAKQLENENVLVYPLDVTKIKSVE 85
Query: 310 EFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAFL 489
F V T+L N ++NNA +M G++EW T + + V VNLLG MR+ +
Sbjct: 86 NFVNSVRTILTQN-NLVLRCLINNAAIMIFGEFEWQTDEQLRNQVEVNLLGTMRITQELM 144
Query: 490 PEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKS 612
P IR RII + SHC +QP+P AAYS +K+
Sbjct: 145 PMIRAHF--------TRIIVISSHCNIQPIPGVAAYSGTKA 177
>UniRef50_Q9VAH3 Cluster: CG12068-PA; n=2; Sophophora|Rep:
CG12068-PA - Drosophila melanogaster (Fruit fly)
Length = 335
Score = 117 bits (281), Expect = 3e-25
Identities = 64/170 (37%), Positives = 96/170 (56%), Gaps = 8/170 (4%)
Frame = +1
Query: 127 LVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCA--------HTFPL 282
+V +TGCDSGLG ++A +T+ I++E AK L+ L + HT L
Sbjct: 28 VVLITGCDSGLGHSMAVYCHESLHMTVISCCHNIKSEGAKLLQGLASAKDGLSRMHTLEL 87
Query: 283 DVTRVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLG 462
D+ +S++ + + +L +P Y+ A++NNAGVM G++EW IE+ ++ NLLG
Sbjct: 88 DLLEPDSIRLVHRQLRDILAKDPSYRLTALINNAGVMCFGEFEWQLTEQIEAQINCNLLG 147
Query: 463 AMRVISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKS 612
MR+ LP +R + + RIINV SHCGLQ LPA Y+ASK+
Sbjct: 148 TMRLTHELLPLLR--------QQQGRIINVTSHCGLQALPALGPYAASKA 189
>UniRef50_Q02338 Cluster: D-beta-hydroxybutyrate dehydrogenase,
mitochondrial precursor; n=9; Amniota|Rep:
D-beta-hydroxybutyrate dehydrogenase, mitochondrial
precursor - Homo sapiens (Human)
Length = 343
Score = 88.6 bits (210), Expect = 1e-16
Identities = 61/177 (34%), Positives = 93/177 (52%), Gaps = 4/177 (2%)
Frame = +1
Query: 121 SRLVAVTGCDSGLGWAVAARLAREGFITIAG-MHKGIETEAAKALEKLCA---HTFPLDV 288
S+ V VTGCDSG G+++A L +GF+ AG + K + K L+ L + T L+V
Sbjct: 55 SKAVLVTGCDSGFGFSLAKHLHSKGFLVFAGCLMKDKGHDGVKELDSLNSDRLRTVQLNV 114
Query: 289 TRVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAM 468
E V++ + V + LKD P+ +VNNAG+ T G+ E+ + + VNL G +
Sbjct: 115 CSSEEVEKVVEIVRSSLKD-PEKGMWGLVNNAGISTFGEVEFTSLETYKQVAEVNLWGTV 173
Query: 469 RVISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKSWPFGVDTMS 639
R+ +FLP IR+ K R++N+ S G PA + Y +K FGV+ S
Sbjct: 174 RMTKSFLPLIRRA--------KGRVVNISSMLGRMANPARSPYCITK---FGVEAFS 219
>UniRef50_Q7Q4T3 Cluster: ENSANGP00000017799; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000017799 - Anopheles gambiae
str. PEST
Length = 344
Score = 87.0 bits (206), Expect = 3e-16
Identities = 52/175 (29%), Positives = 92/175 (52%), Gaps = 5/175 (2%)
Frame = +1
Query: 103 VSAMSVSRLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHT--- 273
+ +S +V +TGCDSGLG+ +A + G +T+ E++ K+L+ T
Sbjct: 41 IRKLSTKDVVIITGCDSGLGYNMACMCLQAG-MTVMATCVSKESDGYKSLQSRGKQTGQL 99
Query: 274 --FPLDVTRVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVH 447
F +D+ ES+ + + N + +A+VNNAGVM G+ EW+++++ + ++
Sbjct: 100 VCFIMDLNSQESIADTHSAIRKWFAANHPARLYALVNNAGVMCFGEAEWLSSNLTKLQLN 159
Query: 448 VNLLGAMRVISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKS 612
VN +G ++ L +R+ + R+I V SHCG Q LP + YSA+K+
Sbjct: 160 VNAIGTIQFTLPLLELVREN--------RARLIVVTSHCGRQALPGLSVYSATKA 206
>UniRef50_A7SKS9 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 323
Score = 84.2 bits (199), Expect = 2e-15
Identities = 53/163 (32%), Positives = 83/163 (50%), Gaps = 3/163 (1%)
Frame = +1
Query: 130 VAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAH---TFPLDVTRVE 300
V +TGCD+G G +A RL + G AG + K L++ C+ T LDVT+
Sbjct: 37 VLITGCDTGFGHQLAKRLDKLGLRVFAGC---LSEGGEKNLQQCCSARLTTIRLDVTKQV 93
Query: 301 SVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVIS 480
+++ + + + A+VNNAG+ + G ++W+T ++ VN+ G + V
Sbjct: 94 DIEKTLCLITQEMASSSGSVLWAIVNNAGIGSGGPFDWITVQQMQRVFDVNVWGLLNVTK 153
Query: 481 AFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
AFLP ++K+ RI+NV S G P P +AYSASK
Sbjct: 154 AFLPLLKKSC--------GRIVNVASCAGKLPGPGLSAYSASK 188
>UniRef50_Q80XN0 Cluster: D-beta-hydroxybutyrate dehydrogenase,
mitochondrial precursor; n=22; Euteleostomi|Rep:
D-beta-hydroxybutyrate dehydrogenase, mitochondrial
precursor - Mus musculus (Mouse)
Length = 343
Score = 83.4 bits (197), Expect = 4e-15
Identities = 56/176 (31%), Positives = 90/176 (51%), Gaps = 4/176 (2%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREGFITIAG-MHKGIETEAAKALEKLCA---HTFPLDVT 291
+ + +TGCDSG G+++A L +GF+ AG + K K L+ L + T L+V
Sbjct: 56 KAILITGCDSGFGFSLAKHLHSKGFLVFAGCLMKDKGDAGVKELDSLKSDRLRTIQLNVC 115
Query: 292 RVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMR 471
E V++ + + + LKD P+ +VNNAG+ T G+ E+ + + VNL G +R
Sbjct: 116 NSEEVEKAVETIRSGLKD-PEKGMWGLVNNAGISTFGEVEFTSMETYKEVAEVNLWGTVR 174
Query: 472 VISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKSWPFGVDTMS 639
+FLP +R+ K R++N+ S G PA + Y +K FGV+ S
Sbjct: 175 TTKSFLPLLRRA--------KGRVVNISSMLGRMANPARSPYCITK---FGVEAFS 219
>UniRef50_Q20012 Cluster: Putative uncharacterized protein dhs-20;
n=1; Caenorhabditis elegans|Rep: Putative
uncharacterized protein dhs-20 - Caenorhabditis elegans
Length = 342
Score = 81.4 bits (192), Expect = 2e-14
Identities = 63/167 (37%), Positives = 86/167 (51%), Gaps = 5/167 (2%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAH----TFPLDVT 291
R + +TGCD+G G +A + A+ GF+ AG + TEAAK LE A+ T PLDV+
Sbjct: 42 RAILITGCDTGFGRELAKKCAKNGFLVFAGC---LTTEAAKTLESESANPRLRTVPLDVS 98
Query: 292 RVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMT-VGKYEWMTASMIESPVHVNLLGAM 468
+ ESV+ K V V K +K VVNNAG+ + G +W + + + VN LG +
Sbjct: 99 KDESVE---KTVEFVKKSLGNHKLWGVVNNAGIFSCYGPDDWCRMNDYKLALDVNCLGVI 155
Query: 469 RVISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
RV AF ++ K A K RI+ V S G PA Y SK
Sbjct: 156 RVTQAF-KKLVKAA-------KGRIVTVTSVNGRLSTPAAGPYVVSK 194
>UniRef50_UPI0000F2B8EE Cluster: PREDICTED: hypothetical protein;
n=1; Monodelphis domestica|Rep: PREDICTED: hypothetical
protein - Monodelphis domestica
Length = 389
Score = 81.0 bits (191), Expect = 2e-14
Identities = 47/132 (35%), Positives = 73/132 (55%), Gaps = 4/132 (3%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREGFITIAGM----HKGIETEAAKALEKLCAHTFPLDVT 291
+ V +TGCD+G G ++A RL GF A +G + +A H LDVT
Sbjct: 43 KAVLITGCDTGFGHSLALRLFSLGFTVFATCLFPDGEGAQRLRQEAGSSCRLHVLKLDVT 102
Query: 292 RVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMR 471
+ + V E +++VL K+ P+ +VNNAG+M VG EW++ ++ + VNLLG++R
Sbjct: 103 QDQDVAEAKEFVL---KNMPENGLWGLVNNAGIMLVGPIEWISFDECKNVIDVNLLGSIR 159
Query: 472 VISAFLPEIRKT 507
FLP I+K+
Sbjct: 160 TTLTFLPLIKKS 171
>UniRef50_Q60M45 Cluster: Putative uncharacterized protein CBG23309;
n=1; Caenorhabditis briggsae|Rep: Putative
uncharacterized protein CBG23309 - Caenorhabditis
briggsae
Length = 356
Score = 81.0 bits (191), Expect = 2e-14
Identities = 62/167 (37%), Positives = 88/167 (52%), Gaps = 5/167 (2%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAH----TFPLDVT 291
R V +TGCD+G G +A + A+ GF+ AG + TEAAK LE A+ T PLDV+
Sbjct: 17 RAVFITGCDTGFGKELAKKCAKNGFMVFAGC---LTTEAAKTLEAEVANPRLKTVPLDVS 73
Query: 292 RVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMT-VGKYEWMTASMIESPVHVNLLGAM 468
+ ESV++ ++V L + +K VVNNAG+ + G +W + + + VN LG +
Sbjct: 74 KDESVEKAAEFVKKYLGN---HKLWGVVNNAGIFSCYGPDDWCRMNDYKLALDVNCLGVI 130
Query: 469 RVISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
RV AF ++ K A K RI+ V S G PA Y SK
Sbjct: 131 RVTQAF-KKLVKAA-------KGRIVTVTSVNGRLSTPAAGPYVVSK 169
>UniRef50_UPI0000F2B793 Cluster: PREDICTED: similar to 17-beta
hydroxysteroid dehydrogenase 2; n=1; Monodelphis
domestica|Rep: PREDICTED: similar to 17-beta
hydroxysteroid dehydrogenase 2 - Monodelphis domestica
Length = 339
Score = 80.6 bits (190), Expect = 3e-14
Identities = 54/167 (32%), Positives = 88/167 (52%), Gaps = 4/167 (2%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAH---TFPLDVTR 294
R V +TG DSG+G A++ L GF G+ + A+AL+K C+ F +D+T+
Sbjct: 72 RAVLITGGDSGIGHALSKYLDELGFTVFVGVLNE-KGPGAEALKKTCSKRTSVFQMDITK 130
Query: 295 VESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVM-TVGKYEWMTASMIESPVHVNLLGAMR 471
++E + V ++ + A+VNNAG++ ++G E + + + VN GA+
Sbjct: 131 PAQIREVQARVAEKVQQTGLW---AIVNNAGILGSIGDGELLPMEVYRQCMDVNFFGAVE 187
Query: 472 VISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKS 612
V AF+P +RK+ K R++NV S G P+ AAY ASK+
Sbjct: 188 VTKAFMPLLRKS--------KGRVVNVSSLAGAMPMKFLAAYCASKA 226
>UniRef50_UPI0000E8001E Cluster: PREDICTED: hypothetical protein;
n=2; Gallus gallus|Rep: PREDICTED: hypothetical protein
- Gallus gallus
Length = 452
Score = 79.4 bits (187), Expect = 7e-14
Identities = 54/134 (40%), Positives = 72/134 (53%), Gaps = 7/134 (5%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREGFITIAG-MHKGIETEAAKALEKLCA------HTFPL 282
R V +TGCDSG G +A RL R GF AG + G E A+ L++ A L
Sbjct: 163 RAVLITGCDSGFGHLLALRLHRLGFTVFAGCLCPG--GEGARRLQREAAGDAGRMRVLRL 220
Query: 283 DVTRVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLG 462
DVTR V ++ VL+ L P+ F +VNNAG+ T G+ W++ E VNLLG
Sbjct: 221 DVTRGRDVLAAKELVLSHL---PERGFWGLVNNAGISTFGETGWLSMEKYEKFADVNLLG 277
Query: 463 AMRVISAFLPEIRK 504
++R AFLP +RK
Sbjct: 278 SIRTTLAFLPLLRK 291
>UniRef50_A7SQ85 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 296
Score = 79.4 bits (187), Expect = 7e-14
Identities = 53/165 (32%), Positives = 80/165 (48%), Gaps = 2/165 (1%)
Frame = +1
Query: 121 SRLVAVTGCDSGLGWAVAARLAREGFITIAGM--HKGIETEAAKALEKLCAHTFPLDVTR 294
SR + VTGCD+G G A RL + GF A +G+ + E++ F LDVT
Sbjct: 6 SRYILVTGCDTGFGKMNAVRLQKLGFYVFATCLTEEGMAEMTGISSERIIP--FRLDVTD 63
Query: 295 VESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRV 474
+++ + +L ++ +VNNAG++ VG +W + I+ VNL G + V
Sbjct: 64 SFQIRQVYTRISELLPEDTG--LWGLVNNAGILQVGPLDWQSLDSIKQTADVNLWGLIDV 121
Query: 475 ISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
FLP ++K K R++N+GS CG LP Y SK
Sbjct: 122 TKTFLPLLKKA--------KGRVVNMGSSCGKITLPYMVPYCISK 158
>UniRef50_UPI0000ECB04E Cluster: Estradiol 17-beta-dehydrogenase 2
(EC 1.1.1.62) (17-beta-HSD 2) (Microsomal
17-beta-hydroxysteroid dehydrogenase) (20 alpha-
hydroxysteroid dehydrogenase) (20-alpha-HSD) (E2DH).;
n=2; Gallus gallus|Rep: Estradiol 17-beta-dehydrogenase
2 (EC 1.1.1.62) (17-beta-HSD 2) (Microsomal
17-beta-hydroxysteroid dehydrogenase) (20 alpha-
hydroxysteroid dehydrogenase) (20-alpha-HSD) (E2DH). -
Gallus gallus
Length = 384
Score = 77.0 bits (181), Expect = 4e-13
Identities = 53/164 (32%), Positives = 82/164 (50%), Gaps = 1/164 (0%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVES 303
+ V +TG D+G+G A+A L GFI AG+ + A+ L + C+ L + +
Sbjct: 81 KAVLITGSDTGIGHALAKYLDNLGFIVFAGVLNK-DGPGAEELRRTCSQRLSLLQLDITN 139
Query: 304 VQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTV-GKYEWMTASMIESPVHVNLLGAMRVIS 480
+ ++ L V + K VVNNAG++ E + SM + VN GA+ V
Sbjct: 140 PTQVKEAYLQVSEKVQKTGLWGVVNNAGILGFPADGELLPMSMYRQCMEVNFFGAVHVSK 199
Query: 481 AFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKS 612
FLP +RK+ + R++N+ S G PLP +AAY ASK+
Sbjct: 200 TFLPLLRKS--------RGRLVNMSSMTGGIPLPRYAAYGASKA 235
>UniRef50_A1I773 Cluster: Oxidoreductase, short-chain
dehydrogenase/reductase family; n=1; Candidatus
Desulfococcus oleovorans Hxd3|Rep: Oxidoreductase,
short-chain dehydrogenase/reductase family - Candidatus
Desulfococcus oleovorans Hxd3
Length = 285
Score = 76.2 bits (179), Expect = 6e-13
Identities = 56/162 (34%), Positives = 79/162 (48%), Gaps = 2/162 (1%)
Frame = +1
Query: 130 VAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFP--LDVTRVES 303
V +TG +G+G A LAR G+ AG+ + EA + H P LDVT ++
Sbjct: 4 VLITGASTGIGRQCALDLARAGWQVFAGVRNPEDGEALVSAGS--GHIIPVILDVTDADT 61
Query: 304 VQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISA 483
+ + K + T L A+VNNAG+ G E++ +M E+ + VN+ G + V A
Sbjct: 62 IGQAAKKLETDLAGKG---LDALVNNAGITVQGPLEFIPLAMFETQMQVNVTGQLAVTQA 118
Query: 484 FLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
FLP IRK K RI+ + S G LP YSASK
Sbjct: 119 FLPLIRKA--------KGRIVFMSSESGRNTLPLLGPYSASK 152
>UniRef50_Q5EB01 Cluster: Zgc:113142; n=4; Clupeocephala|Rep:
Zgc:113142 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 359
Score = 74.9 bits (176), Expect = 1e-12
Identities = 48/128 (37%), Positives = 63/128 (49%), Gaps = 2/128 (1%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHT--FPLDVTRV 297
R V +TGCDSG G+ +A +L GF AG A +E+ LDVT
Sbjct: 52 RAVLITGCDSGFGYHLAKKLDLMGFTVFAGCLCPEGPGARSLVEESSKRVKILQLDVTNE 111
Query: 298 ESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVI 477
E + + +V L P +AVVNNAG+ G+ EW TA + VNL GA+RV
Sbjct: 112 EHISSAKDFVEANL---PVKGLYAVVNNAGISDWGETEWSTAEDFQKMADVNLFGAIRVT 168
Query: 478 SAFLPEIR 501
FLP +R
Sbjct: 169 IPFLPLVR 176
>UniRef50_A5FMQ8 Cluster: Short-chain dehydrogenase/reductase SDR;
n=5; Bacteroidetes|Rep: Short-chain
dehydrogenase/reductase SDR - Flavobacterium johnsoniae
UW101
Length = 268
Score = 74.5 bits (175), Expect = 2e-12
Identities = 56/174 (32%), Positives = 79/174 (45%)
Frame = +1
Query: 118 VSRLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRV 297
+ + + +TG +GLG + A +G+ IA M + +LE + PLDVT
Sbjct: 1 MQKTIFITGASTGLGKSTAKLFQSKGWQVIATMRNPEKETELTSLENVIV--LPLDVTNS 58
Query: 298 ESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVI 477
E + E T+ KY V+NNAG +G E ++ IE + NL G +R+
Sbjct: 59 EQITE------TIKSITEKYSVDVVLNNAGYGLIGALESLSEIQIERQIVTNLFGVIRIS 112
Query: 478 SAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKSWPFGVDTMS 639
AF P R+ K INV S GL P + YSA+K FGVD S
Sbjct: 113 KAFTPHFRE-------KKSGTFINVTSTFGLIGFPTCSIYSATK---FGVDGFS 156
>UniRef50_Q6P0H9 Cluster: Hydroxysteroid 11-beta dehydrogenase 2;
n=6; Elopocephala|Rep: Hydroxysteroid 11-beta
dehydrogenase 2 - Danio rerio (Zebrafish) (Brachydanio
rerio)
Length = 400
Score = 73.7 bits (173), Expect = 3e-12
Identities = 52/164 (31%), Positives = 76/164 (46%), Gaps = 1/164 (0%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVES 303
+ V +TGCDSG G A A +L GF A + +E E AK L K+C+ L +
Sbjct: 72 KAVFITGCDSGFGNATAKKLDAMGFEVFATV-LNLEGEGAKHLRKVCSSRLTLLQVDITQ 130
Query: 304 VQEFRKYVLTVLKDNPKYKFHAVVNNAG-VMTVGKYEWMTASMIESPVHVNLLGAMRVIS 480
Q+ ++ +L +VNNAG + +G E S + VN G + V
Sbjct: 131 PQQVQQALLDTKAKLGIRDLWGLVNNAGWCVNIGDAELSLMSNYRGCMEVNFFGTVTVTR 190
Query: 481 AFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKS 612
FLP +R++ K RI+ + S G P P A+Y ASK+
Sbjct: 191 TFLPLLRQS--------KGRIVTISSPSGEHPFPCLASYGASKA 226
>UniRef50_A7S3H1 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 344
Score = 73.3 bits (172), Expect = 4e-12
Identities = 55/166 (33%), Positives = 76/166 (45%), Gaps = 3/166 (1%)
Frame = +1
Query: 121 SRLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCA---HTFPLDVT 291
S+ V +TGCDSG G A L G IA + + L+K C TF LDVT
Sbjct: 43 SKYVLITGCDSGFGQETAILLDSLGVHVIATC---LTARGEQELQKECCGRVRTFRLDVT 99
Query: 292 RVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMR 471
+ + VQE + + L VVNNAG+ VG +W+ + +NL G +
Sbjct: 100 KSKEVQEVYRALQEELPHGTG--LWGVVNNAGIAGVGPVDWIPVERFKHVADINLWGLVD 157
Query: 472 VISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
V FLP +++ + RI+NV S G LP + YS SK
Sbjct: 158 VTKTFLPLVKRA--------RGRIVNVTSIAGRFTLPFASPYSVSK 195
>UniRef50_UPI000045B9B2 Cluster: COG1028: Dehydrogenases with
different specificities (related to short-chain alcohol
dehydrogenases); n=1; Nostoc punctiforme PCC 73102|Rep:
COG1028: Dehydrogenases with different specificities
(related to short-chain alcohol dehydrogenases) - Nostoc
punctiforme PCC 73102
Length = 285
Score = 72.9 bits (171), Expect = 6e-12
Identities = 55/164 (33%), Positives = 80/164 (48%), Gaps = 2/164 (1%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFP--LDVTRV 297
R V VTG +G+G A A L + GF AG+ + I+ + K +K P LDVT
Sbjct: 7 RTVVVTGASTGIGQACALLLDQLGFSVFAGVRQNIDAQTLK--QKGSPRLIPIFLDVTDA 64
Query: 298 ESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVI 477
ES+ + V V + +VNNAG+ G E + + + + VN+ G + V
Sbjct: 65 ESIAD---AVDKVTNEVGGTGILGLVNNAGIAIPGPLELLAIAEFQHQMQVNVTGQLAVT 121
Query: 478 SAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
AFL +R++ + RIIN+GS G P P AY+ASK
Sbjct: 122 QAFLGLLRQS--------RGRIINMGSIAGRSPTPFLGAYNASK 157
>UniRef50_UPI000065ECA5 Cluster: Homolog of Homo sapiens
"D-beta-hydroxybutyrate dehydrogenase, mitochondrial
precursor; n=1; Takifugu rubripes|Rep: Homolog of Homo
sapiens "D-beta-hydroxybutyrate dehydrogenase,
mitochondrial precursor - Takifugu rubripes
Length = 298
Score = 72.9 bits (171), Expect = 6e-12
Identities = 49/127 (38%), Positives = 66/127 (51%), Gaps = 3/127 (2%)
Frame = +1
Query: 130 VAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEK--LC-AHTFPLDVTRVE 300
V +TGCDSG G +A L ++GF+ AG + A+ L K C LDVT
Sbjct: 44 VLITGCDSGFGHQLARCLDQKGFVVFAGCLFP-DGNGAQTLTKHSTCNLKVLKLDVTSDA 102
Query: 301 SVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVIS 480
V++ RK VL L P+ AVVNNAG+ + EW T + V +NL G++R
Sbjct: 103 DVEQARKVVLENL---PEKGLWAVVNNAGITQWAEIEWSTIRDFSNMVDINLFGSIRTTI 159
Query: 481 AFLPEIR 501
AFLP +R
Sbjct: 160 AFLPLVR 166
>UniRef50_A7RIH3 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 252
Score = 72.9 bits (171), Expect = 6e-12
Identities = 59/174 (33%), Positives = 77/174 (44%), Gaps = 2/174 (1%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREGFITIAGM--HKGIETEAAKALEKLCAHTFPLDVTRV 297
R V +TGCDSG G A +L GF A KG A E+L T PLDVT
Sbjct: 21 RYVLITGCDSGFGKMAAEQLDNMGFHVFASCLTDKGQAFLKAHCSERLV--TLPLDVTDS 78
Query: 298 ESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVI 477
++E V +L P A++NNA V T G EW+ + VNL G M V
Sbjct: 79 TQIEEAYNIVKCLL---PLKGLWALLNNAAVTTTGPIEWVPMETCRWVLDVNLYGMMDVT 135
Query: 478 SAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKSWPFGVDTMS 639
FLP ++ + RI+N+ S G +P+ Y SK F V+ S
Sbjct: 136 KTFLPLVKTSG--------GRIVNMSSAGGYISVPSIGVYCISK---FAVEAFS 178
>UniRef50_UPI000069F00A Cluster: Estradiol 17-beta-dehydrogenase 2
(EC 1.1.1.62) (17-beta-HSD 2) (Microsomal
17-beta-hydroxysteroid dehydrogenase) (20 alpha-
hydroxysteroid dehydrogenase) (20-alpha-HSD) (E2DH).;
n=1; Xenopus tropicalis|Rep: Estradiol
17-beta-dehydrogenase 2 (EC 1.1.1.62) (17-beta-HSD 2)
(Microsomal 17-beta-hydroxysteroid dehydrogenase) (20
alpha- hydroxysteroid dehydrogenase) (20-alpha-HSD)
(E2DH). - Xenopus tropicalis
Length = 388
Score = 72.5 bits (170), Expect = 8e-12
Identities = 53/164 (32%), Positives = 85/164 (51%), Gaps = 3/164 (1%)
Frame = +1
Query: 130 VAVTGCDSGLGWAVAARLAREGFITIAGM--HKGIETEAAKALEKLCAHTFPLDVTRVES 303
V +TGCDSG G A+A L + G AG+ KG E K + L++T E
Sbjct: 89 VLITGCDSGFGHALAKHLDKLGVHVFAGVLDKKGPGAEELKRVCSTHLCLIQLNITNCEE 148
Query: 304 VQEFRKYVLTVLKDNPKYKFHAVVNNAGVM-TVGKYEWMTASMIESPVHVNLLGAMRVIS 480
+++ K + + ++D + +V+NAGV+ V E + S+ + VN LGA++V
Sbjct: 149 IRKAYKEISSYIQDAGLW---GIVHNAGVLGYVADGELIPFSVYRQCMEVNFLGAVQVTQ 205
Query: 481 AFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKS 612
F P +RK+ K R++++ S G PL FAAY++SK+
Sbjct: 206 IFAPLLRKS--------KGRLVSISSMGGHVPLNGFAAYASSKA 241
>UniRef50_Q97DY5 Cluster: Short-chain alcohol dehydrogenase family
enzyme; n=1; Clostridium acetobutylicum|Rep: Short-chain
alcohol dehydrogenase family enzyme - Clostridium
acetobutylicum
Length = 266
Score = 72.5 bits (170), Expect = 8e-12
Identities = 55/171 (32%), Positives = 86/171 (50%)
Frame = +1
Query: 127 LVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESV 306
+V +TGC +G+G + L +G+ +A K + + A KL PLDVT+ ESV
Sbjct: 6 VVLITGCSTGIGRELCKILYNKGYTVVATARKVEDLKDLPAALKL-----PLDVTKEESV 60
Query: 307 QEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAF 486
+ K V+ +K +VNNAG G E + S ++S +VN+ G + ++ A
Sbjct: 61 HKAIKEVMLNF-----HKIDILVNNAGYSVRGALEEVNVSDVKSMFNVNVFGIINMLQAV 115
Query: 487 LPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKSWPFGVDTMS 639
+PE+RK + +IIN+GS G P AY A+K F V+ +S
Sbjct: 116 IPEMRK-------RKTGKIINIGSISGKFVQPINGAYCAAK---FAVEALS 156
>UniRef50_A1UBR0 Cluster: Short-chain dehydrogenase/reductase SDR;
n=32; Bacteria|Rep: Short-chain dehydrogenase/reductase
SDR - Mycobacterium sp. (strain KMS)
Length = 289
Score = 72.1 bits (169), Expect = 1e-11
Identities = 58/167 (34%), Positives = 80/167 (47%), Gaps = 2/167 (1%)
Frame = +1
Query: 115 SVSRL--VAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDV 288
SVSR+ V VTGC SG G A A R REG+ +A M + A E+L PLDV
Sbjct: 39 SVSRMKTVLVTGCSSGYGLATAQRFHREGWNVVATMRTPRDEVLAPG-ERLTV--LPLDV 95
Query: 289 TRVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAM 468
T S+ + V P +VNNAG+ VG +E M S++ N G M
Sbjct: 96 TDPASIAD------AVASAGP---IDVLVNNAGIGAVGAFEAMPMSLVRELFETNTFGVM 146
Query: 469 RVISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
+ A +P++R+ + ++NV S L +P AAY+ASK
Sbjct: 147 AMTQAVIPQMRE-------RRSGVVVNVTSSVTLTAMPLAAAYTASK 186
>UniRef50_A1IEM4 Cluster: Oxidoreductase, short-chain
dehydrogenase/reductase family precursor; n=1;
Candidatus Desulfococcus oleovorans Hxd3|Rep:
Oxidoreductase, short-chain dehydrogenase/reductase
family precursor - Candidatus Desulfococcus oleovorans
Hxd3
Length = 289
Score = 72.1 bits (169), Expect = 1e-11
Identities = 48/164 (29%), Positives = 75/164 (45%)
Frame = +1
Query: 118 VSRLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRV 297
+++ + VTG +G+GWA + LA +G+ A + K + + + T +D+
Sbjct: 1 MNKSILVTGASTGIGWATSLELAEKGWRVFAAVRKEADAKKLRDASSGKITTVIMDIVDY 60
Query: 298 ESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVI 477
ESV+ + + L A+ NNAG+ G E + + E + VN+ G + V
Sbjct: 61 ESVKHGAQEIEKALGG---AGLDALFNNAGISVQGPLEIIPIELFEQQIRVNVFGHVFVT 117
Query: 478 SAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
FLP +RK K RI+ S G LP A YSASK
Sbjct: 118 QTFLPLLRKA--------KGRIVFTSSESGRMTLPLMAPYSASK 153
>UniRef50_Q9HYR5 Cluster: Probable short chain dehydrogenase; n=4;
Pseudomonas aeruginosa|Rep: Probable short chain
dehydrogenase - Pseudomonas aeruginosa
Length = 304
Score = 71.3 bits (167), Expect = 2e-11
Identities = 54/169 (31%), Positives = 80/169 (47%), Gaps = 1/169 (0%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEA-AKALEKLCAHTFPLDVTRVE 300
R V +TG SGLG A LA +GF IAG+ + + E A A T +DVT E
Sbjct: 13 RHVLITGASSGLGRETALHLAEQGFQVIAGVRRQEDGERLANACPSGRISTLLIDVTDEE 72
Query: 301 SVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVIS 480
S+ V + D + +VNNAG+ E +++ ++ + VNL+G + V
Sbjct: 73 SIGRAAAQVAEKVGDTGLW---GLVNNAGICISAPLECVSSDLLRRQLEVNLIGQLAVTR 129
Query: 481 AFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKSWPFGV 627
A LP +R+ R++NV S G +P AYSA++ GV
Sbjct: 130 AILPLLRRGG-------AARLVNVTSGLGSVAIPYLGAYSAAQFAKEGV 171
>UniRef50_P50169 Cluster: Retinol dehydrogenase 3; n=25;
Tetrapoda|Rep: Retinol dehydrogenase 3 - Rattus
norvegicus (Rat)
Length = 317
Score = 71.3 bits (167), Expect = 2e-11
Identities = 58/175 (33%), Positives = 85/175 (48%), Gaps = 3/175 (1%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREGFITIAGM--HKGIETEAAKALEKLCAHTFPLDVTRV 297
+ V +TGCDSG G +A +L R G +A KG E +K ++L T LDVT+
Sbjct: 30 KYVFITGCDSGFGNLLARQLDRRGMRVLAACLTEKGAEQLRSKTSDRL--ETVILDVTKT 87
Query: 298 ESVQEFRKYVLTVLKDNPKYKFHAVVNNAGV-MTVGKYEWMTASMIESPVHVNLLGAMRV 474
ES+ ++V + + + +VNNAG+ + VG EWM S + VNLLG + V
Sbjct: 88 ESIVAATQWVKERVGNRGLW---GLVNNAGISVPVGPNEWMRKKDFASVLDVNLLGVIEV 144
Query: 475 ISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKSWPFGVDTMS 639
LP +RK + R++N+ S G L Y SK +GV+ S
Sbjct: 145 TLNMLPLVRKA--------RGRVVNIASTMGRMSLVG-GGYCISK---YGVEAFS 187
>UniRef50_Q6GMC4 Cluster: MGC81883 protein; n=2; Xenopus|Rep:
MGC81883 protein - Xenopus laevis (African clawed frog)
Length = 388
Score = 70.1 bits (164), Expect = 4e-11
Identities = 50/165 (30%), Positives = 76/165 (46%), Gaps = 1/165 (0%)
Frame = +1
Query: 121 SRLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVE 300
+++V +TGCD+G G A +L GF IA + +E+ AK L+K+C+ + +
Sbjct: 86 AKVVFITGCDTGFGNVAAHKLDSMGFKVIATV-LNLESPGAKKLKKICSDNLTIIQMDLT 144
Query: 301 SVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMT-VGKYEWMTASMIESPVHVNLLGAMRVI 477
++ +K T A+VNNAG G E S + + VN G + +
Sbjct: 145 KQEDIKKAQQTTKLHTAGRGLWALVNNAGYCAHFGDAELTLMSTYKGCMDVNFFGTLELT 204
Query: 478 SAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKS 612
A LP IR K RI+ +GS G P AAY +SK+
Sbjct: 205 QALLPFIRYA--------KGRIVTIGSPAGEHSFPYLAAYGSSKA 241
>UniRef50_A0NKJ7 Cluster: Short-chain dehydrogenase; n=2; Oenococcus
oeni|Rep: Short-chain dehydrogenase - Oenococcus oeni
ATCC BAA-1163
Length = 272
Score = 69.7 bits (163), Expect = 5e-11
Identities = 51/166 (30%), Positives = 76/166 (45%)
Frame = +1
Query: 112 MSVSRLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVT 291
M + V +TG SG+G+A A ++ G+ AG + E K L+K TF LD++
Sbjct: 1 MEKQKTVIITGASSGMGFAAAELFSKHGWQVFAGARR---LERMKELKKFGVETFFLDLS 57
Query: 292 RVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMR 471
+ +S++ F + VL D ++NNAG G E + VN+ AMR
Sbjct: 58 KDDSIETFFRQVLQKNDD-----IDVLINNAGYGEYGSLEDTPIEQARAQFQVNVFAAMR 112
Query: 472 VISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
+ LP +RK + K RIIN+ S G P Y A+K
Sbjct: 113 LTQLLLPFMRK-------QHKGRIINISSIAGFLYTPLGGWYDATK 151
>UniRef50_A6E8Y7 Cluster: Short-chain dehydrogenase; n=1; Pedobacter
sp. BAL39|Rep: Short-chain dehydrogenase - Pedobacter
sp. BAL39
Length = 269
Score = 68.5 bits (160), Expect = 1e-10
Identities = 49/160 (30%), Positives = 78/160 (48%)
Frame = +1
Query: 130 VAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESVQ 309
+ +TG SGLG A A +G+ IA M + + +LE++ H +PLDVT + V
Sbjct: 5 IFITGASSGLGKAAAKLFQSKGWTVIATMRDPEKEQELSSLERV--HLYPLDVTNPDQV- 61
Query: 310 EFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAFL 489
+ + VLK +K V NNAG VG +E + + I+ + NL+G +RV F+
Sbjct: 62 --KSTIDEVLKH---FKVDVVFNNAGYGMVGGFESYSENDIQRQIETNLIGVLRVTRPFI 116
Query: 490 PEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
R+ K + ++ S G+ P + YSA+K
Sbjct: 117 TYFRE------QKKQGLLLTTTSAAGIAANPLASVYSATK 150
>UniRef50_Q9GQA9 Cluster: Microsomal retinol dehydrogenase 2; n=3;
Branchiostoma|Rep: Microsomal retinol dehydrogenase 2 -
Branchiostoma floridae (Florida lancelet) (Amphioxus)
Length = 335
Score = 68.1 bits (159), Expect = 2e-10
Identities = 57/178 (32%), Positives = 87/178 (48%), Gaps = 6/178 (3%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKA-LEKLCAHTFP---LDVT 291
+ V +TGCD+G G +A RL + G AG TEA A L + C+ +DV+
Sbjct: 35 KTVLITGCDTGFGNLLAKRLDQLGLRVFAGCL----TEAGVAELRQSCSERLQPIRMDVS 90
Query: 292 RVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTV--GKYEWMTASMIESPVHVNLLGA 465
+SVQ+ + V + + +VNNAG+ V G EW T + ++VNLLG
Sbjct: 91 SSDSVQDGFRVVKEAVGSKGLW---GLVNNAGIAGVAGGTMEWATKEDYQVVLNVNLLGM 147
Query: 466 MRVISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKSWPFGVDTMS 639
+ V FLP ++K+ + R++NV S G +P Y+ SK +GV+ S
Sbjct: 148 IDVTKTFLPLLKKS--------RGRVVNVASAVGRMAVPQAGPYTVSK---YGVEAFS 194
>UniRef50_Q1PLL0 Cluster: 17-beta hydroxysteroid dehydrogenase 2;
n=3; Danio rerio|Rep: 17-beta hydroxysteroid
dehydrogenase 2 - Danio rerio (Zebrafish) (Brachydanio
rerio)
Length = 358
Score = 67.7 bits (158), Expect = 2e-10
Identities = 53/165 (32%), Positives = 78/165 (47%), Gaps = 3/165 (1%)
Frame = +1
Query: 127 LVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAH--TFPLDVTRVE 300
L V CDSG G +A L R G AG+ + A K E + LD+T
Sbjct: 60 LAGVFSCDSGFGHELAQVLDRAGMRVFAGVLDELSPGALKLKESASVNLTVLQLDITNNT 119
Query: 301 SVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMT-VGKYEWMTASMIESPVHVNLLGAMRVI 477
+ + +++ + K A+VNNAGV+ V E + M +S + VN LG++ +
Sbjct: 120 QITQTHQFIKS---QTGKTGLWALVNNAGVLGYVCDGEILPMKMYKSCLDVNFLGSVMMT 176
Query: 478 SAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKS 612
FLP IR++ + R+IN+ S G PL FA Y ASK+
Sbjct: 177 HTFLPLIRQS--------RGRVINITSMAGEVPLVGFAGYGASKA 213
>UniRef50_A3UHW8 Cluster: Oxidoreductase, short-chain
dehydrogenase/reductase family protein; n=1;
Oceanicaulis alexandrii HTCC2633|Rep: Oxidoreductase,
short-chain dehydrogenase/reductase family protein -
Oceanicaulis alexandrii HTCC2633
Length = 287
Score = 67.7 bits (158), Expect = 2e-10
Identities = 51/168 (30%), Positives = 80/168 (47%), Gaps = 2/168 (1%)
Frame = +1
Query: 112 MSVSRLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPL--D 285
MS + V +TG +G+G+A A LA +G+ AG+ K + E A +L A +P+ D
Sbjct: 1 MSEMKRVMITGASTGIGYASAKYLADKGWRVYAGVRKPEDAERLSA--ELGASVYPVLCD 58
Query: 286 VTRVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGA 465
VT ++ + V L+ +VNNAG+ G + + + VN+ G
Sbjct: 59 VTDAGIIKSAAEQVQNDLQGQ---TLDGLVNNAGIAVAGPLLHLPPEEMTRQLDVNVTGQ 115
Query: 466 MRVISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
+RV AF P + A + +P RI+N+ S G Q P Y+ SK
Sbjct: 116 LRVTQAFAPLMGARA-DFDGQP-GRIVNISSVAGFQATPMLTPYACSK 161
>UniRef50_A0KBT1 Cluster: Short-chain dehydrogenase/reductase SDR;
n=4; Proteobacteria|Rep: Short-chain
dehydrogenase/reductase SDR - Burkholderia cenocepacia
(strain HI2424)
Length = 307
Score = 67.7 bits (158), Expect = 2e-10
Identities = 54/168 (32%), Positives = 77/168 (45%), Gaps = 2/168 (1%)
Frame = +1
Query: 112 MSVSRLVAVTGCDSGLGWAVAARLAREGFITIAGMHK--GIETEAAKALEKLCAHTFPLD 285
+++SR + +TG SG G A L+R G A M G A AL LD
Sbjct: 14 LNMSRTILITGASSGFGRDTAETLSRAGHRVFASMRDVAGRNRPHADALRASGVQVVELD 73
Query: 286 VTRVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGA 465
VT SV+ + V +VL+ + ++NNAG+ + G E T +++ VN+ G
Sbjct: 74 VTDDASVE---RGVASVLEHAGR--LDVLINNAGIGSAGVSEAFTTKQVQALFDVNVFGI 128
Query: 466 MRVISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
R+ A LP RK + + I+NVGS G P F Y ASK
Sbjct: 129 QRMSRAVLPTFRK-------QGEGLIVNVGSILGRVTFPFFGLYGASK 169
>UniRef50_Q8U4K9 Cluster: Alcohol dehydrogenase, short chain; n=2;
Pyrococcus furiosus|Rep: Alcohol dehydrogenase, short
chain - Pyrococcus furiosus
Length = 251
Score = 67.7 bits (158), Expect = 2e-10
Identities = 50/151 (33%), Positives = 72/151 (47%), Gaps = 7/151 (4%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREGFITIAGMHK--GIETEAAKALEKLCAHTFP--LDVT 291
++ +TG G+G A+A LA +G+ G +E A + EK F LDV+
Sbjct: 19 KVAVITGASRGIGEAIAKALAEDGYSLALGARSVDRLEKIAKELSEKHGVEVFYDYLDVS 78
Query: 292 RVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMR 471
+ ESV+EF + L D VV NAG+ G+ E +T + VNLLG R
Sbjct: 79 KPESVEEFARKTLAHFGD-----VDVVVANAGLGYFGRLEELTEEQFHEMIEVNLLGVWR 133
Query: 472 VISAFLPEIRKT---AIETTSKPKPRIINVG 555
I AFL +++T AI TS R++ G
Sbjct: 134 TIKAFLNSLKRTGGVAIVVTSDVSARLLPYG 164
>UniRef50_Q1IZR4 Cluster: Short-chain dehydrogenase/reductase SDR
precursor; n=1; Deinococcus geothermalis DSM 11300|Rep:
Short-chain dehydrogenase/reductase SDR precursor -
Deinococcus geothermalis (strain DSM 11300)
Length = 236
Score = 67.3 bits (157), Expect = 3e-10
Identities = 54/164 (32%), Positives = 78/164 (47%), Gaps = 2/164 (1%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREGFITIAGMH--KGIETEAAKALEKLCAHTFPLDVTRV 297
R+VAVTG G+GWAV A L +G IAG +G+ E A+ HT LDVT
Sbjct: 9 RVVAVTGASKGIGWAVVAALTAQGARVIAGARDVRGLSLEGAE------FHT--LDVTDE 60
Query: 298 ESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVI 477
SV F + D A+VNNAGV + +E +T + + N+LG + V
Sbjct: 61 TSVGAFAGAAVRAGVD-------ALVNNAGVGSFQPFEAITVAEYRRVMDTNVLGTVLVT 113
Query: 478 SAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
A +P R+ A + +++N+ S + A Y+ASK
Sbjct: 114 RALIPHFRERAAQGQGS---QVVNITSDVSARTFAGGALYTASK 154
>UniRef50_O16881 Cluster: Dehydrogenases, short chain protein 16;
n=2; Caenorhabditis|Rep: Dehydrogenases, short chain
protein 16 - Caenorhabditis elegans
Length = 388
Score = 67.3 bits (157), Expect = 3e-10
Identities = 51/158 (32%), Positives = 76/158 (48%), Gaps = 7/158 (4%)
Frame = +1
Query: 115 SVSRLVAVTGCDSGLGWAVAARLARE------GFITIAGMHKGIETEAAKALEKLCAHTF 276
S + V +TGCDSG G +A L + T GM K K +T
Sbjct: 30 SSGKYVMITGCDSGFGRLLATSLLDKHVNVFAACFTQQGMASLHSEWKLKKGPKGQLYTL 89
Query: 277 PLDVTRVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTV-GKYEWMTASMIESPVHVN 453
LDVT SV + +V +LK+ K +VNNAG+ ++ G +W + S ++VN
Sbjct: 90 QLDVTSQASVDSAKSFVTKILKEQNS-KLWGLVNNAGIFSIHGPDDWCSVDEYASSLNVN 148
Query: 454 LLGAMRVISAFLPEIRKTAIETTSKPKPRIINVGSHCG 567
LGA+R+ AF+P I+K+ + RI+ +GS G
Sbjct: 149 TLGAVRMCHAFVPLIKKS--------RGRIVTMGSTAG 178
>UniRef50_Q92781 Cluster: 11-cis retinol dehydrogenase; n=60;
Euteleostomi|Rep: 11-cis retinol dehydrogenase - Homo
sapiens (Human)
Length = 318
Score = 67.3 bits (157), Expect = 3e-10
Identities = 48/149 (32%), Positives = 72/149 (48%), Gaps = 4/149 (2%)
Frame = +1
Query: 130 VAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESVQ 309
V +TGCDSG G +A +L + GF +A E + + HT LD+T +SVQ
Sbjct: 31 VFITGCDSGFGRLLALQLDQRGFRVLASCLTPSGAEDLQRVASSRLHTTLLDITDPQSVQ 90
Query: 310 EFRKYVLTVLKDNPKYKFHAVVNNAGVM-TVGKYEWMTASMIESPVHVNLLGAMRVISAF 486
+ K+V +K+ + +VNNAGV +G W+T + ++VN +G + V A
Sbjct: 91 QAAKWVEMHVKEAGLF---GLVNNAGVAGIIGPTPWLTRDDFQRVLNVNTMGPIGVTLAL 147
Query: 487 LP---EIRKTAIETTSKPKPRIINVGSHC 564
LP + R I TS N G +C
Sbjct: 148 LPLLQQARGRVINITSVLGRLAANGGGYC 176
>UniRef50_A6Q6X0 Cluster: Oxidoreductase; n=4; Proteobacteria|Rep:
Oxidoreductase - Sulfurovum sp. (strain NBC37-1)
Length = 270
Score = 66.9 bits (156), Expect = 4e-10
Identities = 52/164 (31%), Positives = 83/164 (50%)
Frame = +1
Query: 118 VSRLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRV 297
+S++V +TG SG+G + LA+ G+I AG K EA + L+ + LDVT
Sbjct: 1 MSKVVLITGASSGMGKRTSEFLAQNGYIVYAGSRKAESMEAKENLKPVY-----LDVTDT 55
Query: 298 ESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVI 477
ES+Q+ V T++++ + K +VNNAG + E T + ++VN+ G ++
Sbjct: 56 ESIQQ---AVETIIQN--EGKIDVLVNNAGYGLLSTVEDGTDEEMFDQLNVNVFGLLKAT 110
Query: 478 SAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
A LP +R + II++ S G LP A Y+ASK
Sbjct: 111 RAVLPHMR-------AAKSGVIIDISSFLGKMGLPLLAHYNASK 147
>UniRef50_A7SRY0 Cluster: Predicted protein; n=3; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 331
Score = 66.5 bits (155), Expect = 5e-10
Identities = 56/174 (32%), Positives = 80/174 (45%), Gaps = 2/174 (1%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREGFITIAGM--HKGIETEAAKALEKLCAHTFPLDVTRV 297
+ V +TGCDSG G A L G IA KG E + ++L A LDVT
Sbjct: 35 KYVLITGCDSGFGRVTAVHLDGLGVHVIACCLTEKGAENLRNECSDRLRA--LLLDVTSS 92
Query: 298 ESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVI 477
+VQ+ + V ++ P +VNNAG + VG EW+ S + VNL G + V
Sbjct: 93 VNVQDVYETVKRIVP--PNIGLWGLVNNAGTLDVGPIEWLPLSSYKHVADVNLWGMIDVT 150
Query: 478 SAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKSWPFGVDTMS 639
AFLP +++ R++NV S G +AY SK +G++ S
Sbjct: 151 KAFLPLVQQA--------HGRVVNVSSITGRFCPKFLSAYVISK---YGIEAFS 193
>UniRef50_Q72GV3 Cluster: Corticosteroid 11-beta-dehydrogenase; n=2;
Thermus thermophilus|Rep: Corticosteroid
11-beta-dehydrogenase - Thermus thermophilus (strain
HB27 / ATCC BAA-163 / DSM 7039)
Length = 274
Score = 66.1 bits (154), Expect = 7e-10
Identities = 51/164 (31%), Positives = 79/164 (48%)
Frame = +1
Query: 118 VSRLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRV 297
++R V VTG SG+G A A L +G+ G+ + E +AA+ ++ LDVTR
Sbjct: 1 MARAVLVTGAGSGIGLATARLLTAKGYRVYGGVRR--EEDAARLAQEGVVPLL-LDVTRE 57
Query: 298 ESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVI 477
E + R+ ++ +V NAG+ G E + S + VN+LGA +
Sbjct: 58 EDLLRARERLVGE-------GLWGLVVNAGIAVAGPLELVPLSAFREALEVNVLGAFATV 110
Query: 478 SAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
AFLP +R + + R++ +GS GL LP Y+ASK
Sbjct: 111 KAFLPLLRAS--------RGRVVLMGSVSGLVALPLMGPYAASK 146
>UniRef50_A1UA98 Cluster: Short-chain dehydrogenase/reductase SDR;
n=6; Mycobacterium|Rep: Short-chain
dehydrogenase/reductase SDR - Mycobacterium sp. (strain
KMS)
Length = 287
Score = 66.1 bits (154), Expect = 7e-10
Identities = 53/174 (30%), Positives = 82/174 (47%), Gaps = 2/174 (1%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVA-ARLAREGFITIAGMHKGIETEAAKALEKLCAHT-FPLDVTRV 297
+ +A+TG G+G+A A A LAR + I ++ A L KL + +PLDVT
Sbjct: 7 KTIAITGAARGIGYATAKALLARGARVVIGDRDVALQESAVAQLTKLGPVSGYPLDVTDR 66
Query: 298 ESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVI 477
ES F L + + ++NNAGVM +G + + I S + VNL G +
Sbjct: 67 ESFATF----LDKARTDGGGHIDVLINNAGVMPIGPFLEQSEQAIRSSIEVNLYGVIAGC 122
Query: 478 SAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKSWPFGVDTMS 639
LP++ ++ + IIN+ S G+ P+P Y +K FGV +S
Sbjct: 123 QLALPDM-------VARGRGHIINIASLSGVIPVPGQVVYVGAK---FGVVGLS 166
>UniRef50_A7RSA6 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 288
Score = 66.1 bits (154), Expect = 7e-10
Identities = 55/183 (30%), Positives = 90/183 (49%), Gaps = 7/183 (3%)
Frame = +1
Query: 112 MSVSRLVAVTGCDSGLGWAVAARLAREG------FITIAGMHK-GIETEAAKALEKLCAH 270
M+ +V +TGC +G+G A A LA++ + T+ + K GI EAA+
Sbjct: 1 MAAPTVVLITGCSTGIGLAAALLLAKDDGRRFKVYATMRNLEKRGILEEAARRQLGDTLI 60
Query: 271 TFPLDVTRVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHV 450
LDVT ESV E + + + + + +VNNAGV +G E T S++ +V
Sbjct: 61 VKQLDVTSDESVTEVLQSIYSAER-----RIDVLVNNAGVGLIGVLETHTMSLVREMFNV 115
Query: 451 NLLGAMRVISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKSWPFGVD 630
N G +R+ A +P++++ IIN+ S G++ +P A Y +SK F V+
Sbjct: 116 NFFGVVRLTKAVIPKMKE-------NHSGHIINITSIGGIRGVPFNAIYCSSK---FAVE 165
Query: 631 TMS 639
M+
Sbjct: 166 GMA 168
>UniRef50_UPI00006A0336 Cluster: D-beta-hydroxybutyrate
dehydrogenase, mitochondrial precursor (EC 1.1.1.30)
(BDH) (3-hydroxybutyrate dehydrogenase).; n=1; Xenopus
tropicalis|Rep: D-beta-hydroxybutyrate dehydrogenase,
mitochondrial precursor (EC 1.1.1.30) (BDH)
(3-hydroxybutyrate dehydrogenase). - Xenopus tropicalis
Length = 312
Score = 65.3 bits (152), Expect = 1e-09
Identities = 52/162 (32%), Positives = 75/162 (46%), Gaps = 2/162 (1%)
Frame = +1
Query: 130 VAVTGCDSGLGWAVAARLAREGFITIAG--MHKGIETEAAKALEKLCAHTFPLDVTRVES 303
V +TGCD+G G+A+A L + GF AG + I+ K T L V + +
Sbjct: 32 VLITGCDTGFGFALAKHLHKLGFTVFAGCLLKVIIQVLLIWPCGKHHQLTAALAVLLIGN 91
Query: 304 VQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISA 483
Q V+ + + VVNNAG+ T G E+ T + + VNL G +R+ A
Sbjct: 92 QQSCHNGVIFTATEAGLW---GVVNNAGISTFGDVEFTTLDKYKEVMDVNLWGTVRITKA 148
Query: 484 FLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
F P IR+ K R++ VGS G P+ + YS SK
Sbjct: 149 FSPLIRQA--------KGRVVCVGSTLGRMCKPSRSCYSISK 182
>UniRef50_UPI00003639C7 Cluster: 11-cis retinol dehydrogenase (EC
1.1.1.105) (11-cis RDH).; n=1; Takifugu rubripes|Rep:
11-cis retinol dehydrogenase (EC 1.1.1.105) (11-cis
RDH). - Takifugu rubripes
Length = 336
Score = 65.3 bits (152), Expect = 1e-09
Identities = 48/149 (32%), Positives = 72/149 (48%), Gaps = 1/149 (0%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVES 303
+ V VTGCDSG G + +L R GF +AG + K + T L+VT ES
Sbjct: 29 KYVFVTGCDSGFGNLLCRKLDRRGFHVLAGCFTEKGADDLKRVAGPNLKTVLLNVTNEES 88
Query: 304 VQEFRKYVLTVLKDNPKYKFHAVVNNAG-VMTVGKYEWMTASMIESPVHVNLLGAMRVIS 480
+Q+ ++ K+ + +VNNAG + +G EWM + + VN+ G + +
Sbjct: 89 IQKAMEW---AKKEVGEKGLWGIVNNAGSSLPMGPSEWMKVEDFQRTLKVNMNGVIAMTM 145
Query: 481 AFLPEIRKTAIETTSKPKPRIINVGSHCG 567
AFLP I+K + RI+NV S G
Sbjct: 146 AFLPLIKKA--------RGRIVNVASVLG 166
>UniRef50_Q7K3N4 Cluster: GH26015p; n=2; Sophophora|Rep: GH26015p -
Drosophila melanogaster (Fruit fly)
Length = 388
Score = 65.3 bits (152), Expect = 1e-09
Identities = 40/129 (31%), Positives = 73/129 (56%), Gaps = 4/129 (3%)
Frame = +1
Query: 130 VAVTGCDSGLGWAVAARLAREGFITIAGMHKGIE-TEAAKALEKLCAHTFPL---DVTRV 297
V +TGC++ L W +A +L GF AG + IE ++ AK L+++ + L DVT
Sbjct: 98 VLITGCEAPLAWYLAKKLDDLGFTVYAGFNTPIEESDEAKILKEVTSGRMKLLHLDVTSE 157
Query: 298 ESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVI 477
+++ E +YV L + + +VV+ A + +G+ EW+ +++ + +NLLG+ R+
Sbjct: 158 KTILEAARYVSQHLPHGAEGLW-SVVHCAHWIALGELEWIPFAVLRKSLDLNLLGSARLT 216
Query: 478 SAFLPEIRK 504
FLP +R+
Sbjct: 217 QIFLPLVRR 225
>UniRef50_A5V3K8 Cluster: Short-chain dehydrogenase/reductase SDR
precursor; n=1; Sphingomonas wittichii RW1|Rep:
Short-chain dehydrogenase/reductase SDR precursor -
Sphingomonas wittichii RW1
Length = 281
Score = 64.9 bits (151), Expect = 2e-09
Identities = 48/162 (29%), Positives = 70/162 (43%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVES 303
R VTG SG+G A AA L G+ + + E D+ +
Sbjct: 2 RAAVVTGASSGIGRATAALLVERGWRVFGSVRTEAQAEELSVALGPALVPLRFDLRDGPA 61
Query: 304 VQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISA 483
+ K V L+ + + +VNNAG+ G + ++ V VNL G +RV+ A
Sbjct: 62 IARAAKQVAAALEGS---RLAGLVNNAGLAHFGPLAVQPIADWQAQVDVNLTGTLRVVQA 118
Query: 484 FLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
FLP + A S P RI+N+ S G LP + Y+ASK
Sbjct: 119 FLPLL--GADRARSGPPGRIVNISSVSGRITLPFTSGYAASK 158
>UniRef50_Q801X5 Cluster: 11beta hydroxysteroid dehydrogenase; n=2;
Elopocephala|Rep: 11beta hydroxysteroid dehydrogenase -
Anguilla japonica (Japanese eel)
Length = 436
Score = 64.5 bits (150), Expect = 2e-09
Identities = 46/164 (28%), Positives = 72/164 (43%), Gaps = 1/164 (0%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVES 303
+ V +TGCDSG G A A L GF A + ++ A L + C+ L +
Sbjct: 64 KAVFITGCDSGFGKATARHLDALGFEVFASV-LDLDGPGATELRRACSSRLTLLQMDITQ 122
Query: 304 VQEFRKYVLTVLKDNPKYKFHAVVNNAGV-MTVGKYEWMTASMIESPVHVNLLGAMRVIS 480
++ ++ +L +VNNAGV + +G E S + VN G + +
Sbjct: 123 PRDIQQALLATKAQLGLRGLWGLVNNAGVCVNIGDAELSLLSNYRGCMEVNFFGTVERLK 182
Query: 481 AFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKS 612
FLP +R+ + R++ + S G P P AAY ASK+
Sbjct: 183 TFLPLLRQA--------QGRLVTISSPSGEHPFPCLAAYGASKA 218
>UniRef50_Q081K4 Cluster: Short-chain dehydrogenase/reductase SDR;
n=2; Alteromonadales|Rep: Short-chain
dehydrogenase/reductase SDR - Shewanella frigidimarina
(strain NCIMB 400)
Length = 276
Score = 64.5 bits (150), Expect = 2e-09
Identities = 46/167 (27%), Positives = 84/167 (50%), Gaps = 3/167 (1%)
Frame = +1
Query: 121 SRLVAVTGCDSGLGWAVAARLARE-GFITIAGMHKGIETEAAKALEKLCAHTF--PLDVT 291
S+ V VTG SGLG A+A + A + + +A ++K + + ++ L F P D+T
Sbjct: 7 SQNVVVTGAASGLGKALALKWASQHAEVCVADINKPAGEQVCQEIQALGGKAFFVPCDIT 66
Query: 292 RVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMR 471
+S+ ++ VL + ++ ++NNAGV + K E + +NL G +
Sbjct: 67 NTDSITA----LVQVLNERWQH-IDVLINNAGVASADKIEVEPILQWRWVMEINLFGIVN 121
Query: 472 VISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKS 612
+ F+P ++ + + I+NV S GL P+P ++Y+ASK+
Sbjct: 122 MCQQFVPIFKQQGVGS-------IVNVASQAGLTPIPFMSSYNASKA 161
>UniRef50_Q2JVU3 Cluster: Oxidoreductase, short chain
dehydrogenase/reductase family; n=5; Cyanobacteria|Rep:
Oxidoreductase, short chain dehydrogenase/reductase
family - Synechococcus sp. (strain JA-3-3Ab)
(Cyanobacteria bacteriumYellowstone A-Prime)
Length = 280
Score = 64.1 bits (149), Expect = 3e-09
Identities = 55/166 (33%), Positives = 80/166 (48%), Gaps = 5/166 (3%)
Frame = +1
Query: 127 LVAVTGCDSGLGWAVAARLAREGF-ITIAGMHKGIETEAAKALEK-LCAHTF--PLDVTR 294
+V +TG G+G A A AR G+ + +A + A LE+ L A P DVT+
Sbjct: 4 VVLITGASEGIGRATAFTFARGGYRLALAARTAETLRQTAIELEQSLNAEVLAVPTDVTQ 63
Query: 295 VESVQEFRKYVLTVLKDNPKY-KFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMR 471
E VQ + L +Y + ++NNAG+ G + T ++ + VN G +
Sbjct: 64 PEQVQNLVERTLE------RYGRIDCLINNAGICLKGPFLQTTLEHWQALMAVNFWGYLY 117
Query: 472 VISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
I A LP++ K + K +IINVGS G PLP +AY ASK
Sbjct: 118 TIRAVLPDMLK-------RKKGQIINVGSVGGKMPLPQMSAYCASK 156
>UniRef50_A7RZX3 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 328
Score = 64.1 bits (149), Expect = 3e-09
Identities = 54/176 (30%), Positives = 77/176 (43%), Gaps = 3/176 (1%)
Frame = +1
Query: 121 SRLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCA---HTFPLDVT 291
+R V +TGCDSG G A A +L G AG + A L + C+ T LDVT
Sbjct: 38 NRHVLITGCDSGFGRAAAIKLDELGLSVFAGC---LTESGASKLARQCSDRLQTLILDVT 94
Query: 292 RVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMR 471
+ +++ + V L + +VNNAG+ E S + VNL G +
Sbjct: 95 NPDDIKKAHEQVKQHLPQHT--GLWGLVNNAGIAMFTAVELTPLSEYKKMADVNLWGLID 152
Query: 472 VISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKSWPFGVDTMS 639
V FLP IRK R++N+ S G +P YS +K +GV+ S
Sbjct: 153 VTLTFLPLIRKCG--------GRVVNISSIAGRLSIPNTGPYSVTK---YGVEAFS 197
>UniRef50_O14756 Cluster: Hydroxysteroid 17-beta dehydrogenase 6
precursor; n=35; Tetrapoda|Rep: Hydroxysteroid 17-beta
dehydrogenase 6 precursor - Homo sapiens (Human)
Length = 317
Score = 64.1 bits (149), Expect = 3e-09
Identities = 47/151 (31%), Positives = 77/151 (50%), Gaps = 3/151 (1%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREGFITIAG--MHKGIETEAAKALEKLCAHTFPLDVTRV 297
+ V +TGCDSG G +A +L G +A KG E + ++L T LDVT++
Sbjct: 30 KYVFITGCDSGFGNLLARQLDARGLRVLAACLTEKGAEQLRGQTSDRL--ETVTLDVTKM 87
Query: 298 ESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMT-VGKYEWMTASMIESPVHVNLLGAMRV 474
ES+ ++V + D + +VNNAG++T + EW+ + + VNL+G ++V
Sbjct: 88 ESIAAATQWVKEHVGDRGLW---GLVNNAGILTPITLCEWLNTEDSMNMLKVNLIGVIQV 144
Query: 475 ISAFLPEIRKTAIETTSKPKPRIINVGSHCG 567
+ LP +R+ + RI+NV S G
Sbjct: 145 TLSMLPLVRRA--------RGRIVNVSSILG 167
>UniRef50_Q0AKR3 Cluster: Short-chain dehydrogenase/reductase SDR
precursor; n=1; Maricaulis maris MCS10|Rep: Short-chain
dehydrogenase/reductase SDR precursor - Maricaulis maris
(strain MCS10)
Length = 289
Score = 63.7 bits (148), Expect = 4e-09
Identities = 53/160 (33%), Positives = 76/160 (47%), Gaps = 2/160 (1%)
Frame = +1
Query: 136 VTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFP--LDVTRVESVQ 309
VTG +G+G A A RL EG+ AG+ K + E KA +L A+ P +DVT +SV+
Sbjct: 10 VTGASTGIGAACAKRLVDEGWRVFAGVRKNEDGERLKA--ELGANLIPVTIDVTDTDSVR 67
Query: 310 EFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAFL 489
V L D K +VNNAG+ G + ++ + VN+ G +RV AF
Sbjct: 68 AAAAIVREAL-DGQTLK--GLVNNAGIAVAGPMLELPIEEFQNQMDVNVTGIVRVTQAFG 124
Query: 490 PEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
P + E + RI+ + S G P Y+ASK
Sbjct: 125 PLL--GVDEGLTGGPGRIVMMSSVAGEMGAPFLGPYAASK 162
>UniRef50_O01758 Cluster: Dehydrogenases, short chain protein 2,
isoform a; n=4; Caenorhabditis|Rep: Dehydrogenases,
short chain protein 2, isoform a - Caenorhabditis
elegans
Length = 368
Score = 63.7 bits (148), Expect = 4e-09
Identities = 56/172 (32%), Positives = 83/172 (48%), Gaps = 10/172 (5%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREGFITIAG--MHKGIETEAAKALEKL----CAHTFPLD 285
R V +TGCDSG G +A + +G AG +GIE+ +A+A + + F +D
Sbjct: 70 RAVFITGCDSGFGRGLALKCLEQGMPVFAGCLTEQGIESLSAEARKSIGNGRSLDAFLMD 129
Query: 286 VTRVESVQEFRKYVLTVLKDNPKY-KFHAVVNNAGVMTVGKY---EWMTASMIESPVHVN 453
VT ESV E K + K +Y HAVVNNAG+ GK+ +++ + ++N
Sbjct: 130 VTSDESVGEVAK---RLEKKCEQYGGLHAVVNNAGI--TGKHIADDFLDINEYLKVANIN 184
Query: 454 LLGAMRVISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
L G +R A ++K K + R++ V S C LP YS SK
Sbjct: 185 LWGPIRTTMA----VKK----LLKKARGRVVTVASICARVGLPGLGPYSVSK 228
>UniRef50_A5DIM4 Cluster: Putative uncharacterized protein; n=1;
Pichia guilliermondii|Rep: Putative uncharacterized
protein - Pichia guilliermondii (Yeast) (Candida
guilliermondii)
Length = 289
Score = 63.7 bits (148), Expect = 4e-09
Identities = 46/158 (29%), Positives = 72/158 (45%)
Frame = +1
Query: 136 VTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESVQEF 315
VTG SG+G+A+A LA G+ AG + K LE L TF LDV +ES++
Sbjct: 8 VTGASSGIGYALAIELAERGYRVFAGARR---LSRMKPLEDLGITTFELDVGSLESIERA 64
Query: 316 RKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAFLPE 495
+++ +N K + NNAG+ + + +N+ G +R+I P
Sbjct: 65 VEFI----SENTGGKLDLLFNNAGIQCFSPAVEVDDEKFQKCFQINVYGPIRLIRELAPL 120
Query: 496 IRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
+ K+ + I GS GL P P + Y+A+K
Sbjct: 121 VIKS--------RGVIAFTGSTAGLNPFPFLSIYAATK 150
>UniRef50_A1ZFM2 Cluster: Oxidoreductase; n=1; Microscilla marina
ATCC 23134|Rep: Oxidoreductase - Microscilla marina ATCC
23134
Length = 264
Score = 63.3 bits (147), Expect = 5e-09
Identities = 50/174 (28%), Positives = 85/174 (48%)
Frame = +1
Query: 118 VSRLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRV 297
+S+++ +TG SG+G ++A L ++G+ + + A K L+ +D+T
Sbjct: 1 MSKVILITGASSGIGNSMAVYLQQQGYTAYGTSRRAMPDGAVKMLK--------MDITNE 52
Query: 298 ESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVI 477
+ + K V+ +N + +VNNAG+ T G E S IE N++G +R+
Sbjct: 53 TEIVQGVKQVI----ENEGH-IDVLVNNAGLGTAGALEETPLSDIEQVFATNVMGVVRLT 107
Query: 478 SAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKSWPFGVDTMS 639
LP +RK + +IIN+GS G+ LP A Y ASK F +D ++
Sbjct: 108 QEVLPYMRK-------QQSGKIINIGSIGGVMGLPYRATYCASK---FAIDGLT 151
>UniRef50_A2TZE3 Cluster: Putative dehydrogenase; n=1; Polaribacter
dokdonensis MED152|Rep: Putative dehydrogenase -
Polaribacter dokdonensis MED152
Length = 277
Score = 62.9 bits (146), Expect = 6e-09
Identities = 42/163 (25%), Positives = 74/163 (45%)
Frame = +1
Query: 121 SRLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVE 300
+++ +TG SGLG A+A + +G I K + + A LD+T +
Sbjct: 3 NKIWLITGISSGLGKALAESVIEQGDFVIGTFRKQSQVDEFNKNSTKNAQAILLDITNEK 62
Query: 301 SVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVIS 480
S+++ K +++ K +VNNAGV VG E + + + N G +++
Sbjct: 63 SIEDNIKNIIS-----EHVKIDVLVNNAGVGFVGAVEETSLKEVRTVFEPNFFGTLKMTQ 117
Query: 481 AFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
+ LP +RK + I+ + SH G++ F Y+ASK
Sbjct: 118 SVLPYMRK-------EKSGNIVQISSHGGIKAFAGFGIYNASK 153
>UniRef50_A7SME4 Cluster: Predicted protein; n=8; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 338
Score = 62.9 bits (146), Expect = 6e-09
Identities = 55/176 (31%), Positives = 76/176 (43%), Gaps = 3/176 (1%)
Frame = +1
Query: 121 SRLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHT---FPLDVT 291
++ V VTGCDSG G + RL GF + + LE+ C+ +DVT
Sbjct: 48 NKYVLVTGCDSGFGRDLVIRLDGMGFHVFGAC---LTQPGKRDLEQTCSKRTVGLLMDVT 104
Query: 292 RVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMR 471
E + E + V VL AV NNAG MT+ EW + VNL G +
Sbjct: 105 SHEQIIEAFEQVKRVLPSGTG--LWAVYNNAGYMTLAPLEWFPLDDYKRMADVNLWGLVD 162
Query: 472 VISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKSWPFGVDTMS 639
V FLP ++ + R++NV S GL A YS +K +GV+ S
Sbjct: 163 VSKTFLPLVKMA--------RGRVVNVASTVGLIANELTAPYSITK---YGVEAFS 207
>UniRef50_P37059 Cluster: Estradiol 17-beta-dehydrogenase 2; n=16;
Mammalia|Rep: Estradiol 17-beta-dehydrogenase 2 - Homo
sapiens (Human)
Length = 387
Score = 62.9 bits (146), Expect = 6e-09
Identities = 53/169 (31%), Positives = 82/169 (48%), Gaps = 6/169 (3%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCA---HTFPLDVTR 294
+ V VTG D GLG A+ L GF AG+ A+ L + C+ +D+T+
Sbjct: 83 KAVLVTGGDCGLGHALCKYLDELGFTVFAGVLNE-NGPGAEELRRTCSPRLSVLQMDITK 141
Query: 295 VESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVM---TVGKYEWMTASMIESPVHVNLLGA 465
+++ V +L+D + AV+NNAGV+ T G+ MT + + VN G
Sbjct: 142 PVQIKDAYSKVAAMLQDRGLW---AVINNAGVLGFPTDGELLLMTD--YKQCMAVNFFGT 196
Query: 466 MRVISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKS 612
+ V FLP +RK+ K R++NV S G P+ A+Y +SK+
Sbjct: 197 VEVTKTFLPLLRKS--------KGRLVNVSSMGGGAPMERLASYGSSKA 237
>UniRef50_Q166N1 Cluster: Oxidoreductase, putative; n=2;
Rhodobacteraceae|Rep: Oxidoreductase, putative -
Roseobacter denitrificans (strain ATCC 33942 / OCh 114)
(Erythrobactersp. (strain OCh 114)) (Roseobacter
denitrificans)
Length = 294
Score = 62.5 bits (145), Expect = 8e-09
Identities = 54/174 (31%), Positives = 78/174 (44%), Gaps = 8/174 (4%)
Frame = +1
Query: 112 MSVSRLVAVTGCDSGLGWAVAARLAREGFITIAGMHK--GIETEAAKAL------EKLCA 267
M+ ++ + +TG G+G + LA G AGM G +AA A+ E+L
Sbjct: 1 MTDTKTILITGASRGIGHLASLALAAHGHRVYAGMRDIAGSNKDAASAMQAQAQAERLNL 60
Query: 268 HTFPLDVTRVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVH 447
LDVT ++ Q + + D P +VNNAGVM VG E T +
Sbjct: 61 VPLELDVTNAQACQTA---IDKIEADGP---LDVLVNNAGVMPVGLTEAFTMEQAKDVFD 114
Query: 448 VNLLGAMRVISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
VN+ G MR+ A LP +R ++ +IN+ S G +P F Y ASK
Sbjct: 115 VNVYGIMRLTRAALPCMR-------ARKSGLVINLSSSAGRFGMPYFGIYCASK 161
>UniRef50_UPI0000587D40 Cluster: PREDICTED: similar to Retinol
dehydrogenase 8 like; n=4; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to Retinol
dehydrogenase 8 like - Strongylocentrotus purpuratus
Length = 302
Score = 62.1 bits (144), Expect = 1e-08
Identities = 56/170 (32%), Positives = 82/170 (48%), Gaps = 8/170 (4%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLARE---GFITIAGMH----KG-IETEAAKALEKLCAHTFP 279
R+ +TGC SG+G + A +A++ G+I A M KG +E A L K T
Sbjct: 4 RVAIITGCSSGIGLSTAVMMAKDPSKGYIVYATMRNLAKKGDLEKAAGATLNKTLFIT-Q 62
Query: 280 LDVTRVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLL 459
LDVTR +S++ K V T K + +VNNAG + G E +T + + VN
Sbjct: 63 LDVTRGDSIKRAVKDVFTKHK-----RIDILVNNAGHGSSGYIELVTDQQMRALFDVNFF 117
Query: 460 GAMRVISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
G + +I LP ++K + RII+V S G+ P Y+ASK
Sbjct: 118 GVVHLIQEVLPIMKK-------QRSGRIISVSSVGGITAWPFGEIYAASK 160
>UniRef50_Q4S323 Cluster: Chromosome 3 SCAF14756, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 3 SCAF14756, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 536
Score = 61.7 bits (143), Expect = 1e-08
Identities = 53/154 (34%), Positives = 77/154 (50%), Gaps = 5/154 (3%)
Frame = +1
Query: 121 SRLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAH---TFPLDVT 291
S+ V +TGCDSG G +A L ++GF IA + + L+K C+ T LDV
Sbjct: 256 SKYVYITGCDSGFGNLLARHLDQQGFRVIASC---FTEKGEEDLKKSCSSNLITAHLDVR 312
Query: 292 RVESVQEFRKYVLTVLKDN-PKYKFHAVVNNAGV-MTVGKYEWMTASMIESPVHVNLLGA 465
+SV + V ++KD + AVVNNAGV + +W+T ES + VNL G
Sbjct: 313 SKDSVAK----VAAMIKDKVGQQGLWAVVNNAGVSVPSAPCDWLTIDDYESMLQVNLNGV 368
Query: 466 MRVISAFLPEIRKTAIETTSKPKPRIINVGSHCG 567
+ V + LP I+K + R++NV S G
Sbjct: 369 IAVTLSVLPLIKKA--------RGRVVNVASVFG 394
Score = 52.8 bits (121), Expect = 7e-06
Identities = 52/168 (30%), Positives = 78/168 (46%), Gaps = 4/168 (2%)
Frame = +1
Query: 121 SRLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAH---TFPLDVT 291
S+ V +TGCDSG G +A L ++GF IA + + L+K C+ T LDV
Sbjct: 29 SKYVYITGCDSGFGNLLARHLDQQGFRVIASC---FTEKGEEDLKKSCSSNLITAHLDVR 85
Query: 292 RVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGV-MTVGKYEWMTASMIESPVHVNLLGAM 468
+SV + V ++KD V GV + G +W+T S + VNL+G +
Sbjct: 86 SKDSVAK----VAAMIKDK--------VGQQGVTVPSGPCDWLTIDDYRSLLEVNLVGVI 133
Query: 469 RVISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKS 612
V + LP I+K + R++N+ S G + AY SKS
Sbjct: 134 SVTLSVLPLIKKA--------RGRVVNMASVAGRLSMSG-GAYPVSKS 172
>UniRef50_Q9PBQ8 Cluster: Oxidoreductase; n=11; Proteobacteria|Rep:
Oxidoreductase - Xylella fastidiosa
Length = 268
Score = 61.7 bits (143), Expect = 1e-08
Identities = 50/166 (30%), Positives = 79/166 (47%)
Frame = +1
Query: 112 MSVSRLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVT 291
MS S++V +TG SG+G A A LA++G + E A+A+ + +D+
Sbjct: 1 MSNSKVVVITGVSSGIGRATALILAKQGCQVFGTVRNA---EKAQAIPGVVL--VEMDIR 55
Query: 292 RVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMR 471
SV+ + ++ K + +VNNAGV +G E + + ++ NL G +
Sbjct: 56 DDVSVERGIQNIMAQAK-----RIDVLVNNAGVTLLGATEETSVTEAKTLFDTNLFGMLC 110
Query: 472 VISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
I A LP +R+ + RI+N+ S G P P A YSASK
Sbjct: 111 TIQAVLPHMRE-------QRSGRIVNISSVLGFLPAPYMALYSASK 149
>UniRef50_Q222H9 Cluster: Short-chain dehydrogenase/reductase SDR;
n=2; Bacteria|Rep: Short-chain dehydrogenase/reductase
SDR - Rhodoferax ferrireducens (strain DSM 15236 / ATCC
BAA-621 / T118)
Length = 267
Score = 61.7 bits (143), Expect = 1e-08
Identities = 46/161 (28%), Positives = 74/161 (45%), Gaps = 1/161 (0%)
Frame = +1
Query: 130 VAVTGCDSGLGWAVAARLAREG-FITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESV 306
+ VTG +G+G A A R AR G F+ + + E A LE C LDVT ++
Sbjct: 12 IFVTGAATGIGRACAERFARHGWFVGLYDIDADGAAEVAATLEHGCVVAGALDVTDPDAW 71
Query: 307 QEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAF 486
+ L + + + NNAGV+T G +E + + + ++VN+LG + +
Sbjct: 72 ----RVALAQFWEKSGQRLDVLFNNAGVLTAGPFETVELARHQGMLNVNVLGMINGCHSA 127
Query: 487 LPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
+R+T P R+IN+ S + P YSA+K
Sbjct: 128 FDYLRRT-------PGARVINMASATAIYGQPDLVTYSATK 161
>UniRef50_Q0SDG7 Cluster: Short chain dehydrogenase; n=3;
Nocardiaceae|Rep: Short chain dehydrogenase -
Rhodococcus sp. (strain RHA1)
Length = 286
Score = 61.7 bits (143), Expect = 1e-08
Identities = 50/167 (29%), Positives = 80/167 (47%), Gaps = 1/167 (0%)
Frame = +1
Query: 130 VAVTGCDSGLGWAVAARLAREGF-ITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESV 306
V VTG G+G A A A G + I + + + E A ++ A + +DVT ES
Sbjct: 19 VVVTGGGRGIGRATAELFAARGATVCIGDLDRAVADETAA---EIGARAYTVDVTSAES- 74
Query: 307 QEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAF 486
+R++V VL D + +VNNAGVM +G + + + ++VN+ G + +
Sbjct: 75 --WRRFVDAVLADCDR--IDVLVNNAGVMPLGGFLEESDATSRMTMNVNVWGPLHGMRMV 130
Query: 487 LPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKSWPFGV 627
LP + + + I+NV S G P+P A Y+ASK G+
Sbjct: 131 LPGM-------VERGRGHIVNVASMAGKLPVPGMAVYNASKFGAVGL 170
>UniRef50_A5V6Z5 Cluster: Short-chain dehydrogenase/reductase SDR
precursor; n=1; Sphingomonas wittichii RW1|Rep:
Short-chain dehydrogenase/reductase SDR precursor -
Sphingomonas wittichii RW1
Length = 298
Score = 61.7 bits (143), Expect = 1e-08
Identities = 56/168 (33%), Positives = 81/168 (48%), Gaps = 6/168 (3%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREGFITIAGMH-----KGIETEA-AKALEKLCAHTFPLD 285
R+V VTGC SG+G A A G +A + + EA A+AL+ L PLD
Sbjct: 2 RVVVVTGCSSGIGLETALAFAAAGDTVVATVRDPQRAATLRAEAEARALDILIE---PLD 58
Query: 286 VTRVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGA 465
VTR S F +V V+ + + +VNNAG++ G +E + + + + N GA
Sbjct: 59 VTRSAS---FAGFVDGVVGRHG--RIDVLVNNAGMLPAGAFEDIDEAGLRLVMETNFFGA 113
Query: 466 MRVISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
++ A LP +R+ T I+N+ S GL AAYSASK
Sbjct: 114 ALLMKAVLPVMRRQRSGT-------IVNISSLSGLAARAGDAAYSASK 154
>UniRef50_A7RYH1 Cluster: Predicted protein; n=7; Eumetazoa|Rep:
Predicted protein - Nematostella vectensis
Length = 180
Score = 61.7 bits (143), Expect = 1e-08
Identities = 51/180 (28%), Positives = 86/180 (47%), Gaps = 8/180 (4%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREG------FITIAGMHK--GIETEAAKALEKLCAHTFP 279
++ +TGC SG+G A A+ LA++G + T+ + K +E+ AL
Sbjct: 4 KVAVITGCSSGIGLATASILAKDGEKRFRVYATMRNLDKKGSLESACQNALGDTL-FIRE 62
Query: 280 LDVTRVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLL 459
LDV+ +SV+E L + + + + +VNNAG+ +G E T S+++ + N
Sbjct: 63 LDVSSDDSVEE----ALNAIYEE-EGRIDILVNNAGISHIGMLETQTQSLVKETFNTNFF 117
Query: 460 GAMRVISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKSWPFGVDTMS 639
G +R+ A +P ++ S IIN+ S G +P Y ASK F V+ +S
Sbjct: 118 GVLRMSKAVIPRMK-------SDHSGHIINISSTAGHTGMPFTGLYCASK---FAVEGLS 167
>UniRef50_UPI0000E47390 Cluster: PREDICTED: similar to retinol
dehydrogenase 8 (all-trans), partial; n=4;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
retinol dehydrogenase 8 (all-trans), partial -
Strongylocentrotus purpuratus
Length = 216
Score = 61.3 bits (142), Expect = 2e-08
Identities = 51/169 (30%), Positives = 82/169 (48%), Gaps = 8/169 (4%)
Frame = +1
Query: 127 LVAVTGCDSGLGWAVAARLARE---GFITIAGMH-----KGIETEAAKALEKLCAHTFPL 282
+V ++GC +G+G A+AARLA++ ++ A M +G+E AL+K L
Sbjct: 5 VVLISGCSTGIGLALAARLAQDPDKKYLVYATMRNLAKKEGLEKATGDALDK-TLFVRQL 63
Query: 283 DVTRVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLG 462
DVT + V+ ++++ + +VNNAG G E M+ +S N G
Sbjct: 64 DVTVDDQVKSIFEFIM-----GKHGRVDVLVNNAGFGFFGPLEAMSMEKAKSMFDTNYFG 118
Query: 463 AMRVISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
+R+I A LP ++K + RI+N+ S G LP Y+ASK
Sbjct: 119 TVRLIRAALPIMKK-------QKSGRIVNISSILGHLALPYMDMYNASK 160
>UniRef50_Q82RJ3 Cluster: Putative dehydrogenase; n=1; Streptomyces
avermitilis|Rep: Putative dehydrogenase - Streptomyces
avermitilis
Length = 270
Score = 61.3 bits (142), Expect = 2e-08
Identities = 53/167 (31%), Positives = 79/167 (47%), Gaps = 1/167 (0%)
Frame = +1
Query: 112 MSVSRLVA-VTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDV 288
M+ +R VA VTG SG+G A L GF +AG G +T L+ + F LDV
Sbjct: 1 MTTNRPVALVTGASSGIGKQTALALVAAGF-EVAGT--GRDTSRVTPLQGVTF--FDLDV 55
Query: 289 TRVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAM 468
+ V + V+ + +VNNAGV ++G E + + + +N+ G M
Sbjct: 56 VSDKLVTAVVQQVIERFG-----RIDVLVNNAGVGSIGAVEETSLAQAQGVFDINVFGVM 110
Query: 469 RVISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
R++ LP +R ++ + RIIN+ S G P P A Y ASK
Sbjct: 111 RMVKEVLPHMR-------ARGRGRIINLSSVQGFIPAPYMAVYGASK 150
>UniRef50_Q2YCW1 Cluster: Short-chain dehydrogenase/reductase SDR
precursor; n=2; Nitrosospira multiformis ATCC 25196|Rep:
Short-chain dehydrogenase/reductase SDR precursor -
Nitrosospira multiformis (strain ATCC 25196 / NCIMB
11849)
Length = 272
Score = 61.3 bits (142), Expect = 2e-08
Identities = 49/161 (30%), Positives = 76/161 (47%)
Frame = +1
Query: 127 LVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESV 306
+ VTG SG+G A A LA+ G+ A + E ++ E++ LDVT E+V
Sbjct: 5 IALVTGASSGIGRATAELLAQNGYYVFAIARRKYRLEQIRS-ERI--EPIILDVTDDEAV 61
Query: 307 QEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAF 486
++ YV++ K + +VNNAG+ +G E + + VNL G R + A
Sbjct: 62 RKAIGYVIST-----KSRIDLLVNNAGISQLGAVECVPLEAARYQLEVNLFGYARFMQAV 116
Query: 487 LPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
LP +R ++ I+N+ S +P F YSASK
Sbjct: 117 LPHMR-------NQKSGCIVNIVSVLSRISVPGFGWYSASK 150
>UniRef50_A1G780 Cluster: Short-chain dehydrogenase/reductase SDR
precursor; n=3; Salinispora|Rep: Short-chain
dehydrogenase/reductase SDR precursor - Salinispora
arenicola CNS205
Length = 286
Score = 61.3 bits (142), Expect = 2e-08
Identities = 48/165 (29%), Positives = 75/165 (45%)
Frame = +1
Query: 115 SVSRLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTR 294
+ +R V +TG SG+G A A AR G+ T+A M + A A + + +
Sbjct: 4 ATNRCVLITGTSSGIGLATAIACARAGWTTVATMRDTTKASALLAAAEAAGVSLDVRELE 63
Query: 295 VESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRV 474
V S R+ V V+ ++ + AVVNNAG +G E + + + V VN G ++V
Sbjct: 64 VTSDASVRECVGAVVAEHG--RLDAVVNNAGAAYIGTLENDDLADVRACVEVNFFGVIQV 121
Query: 475 ISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
A +P +R + R+I + S G P AY A+K
Sbjct: 122 SHAAMPHLRASG--------GRLITISSVGGSVGQPFNEAYCAAK 158
>UniRef50_Q3IVD0 Cluster: Short-chain alcohol dehydrogenases; n=2;
Rhodobacteraceae|Rep: Short-chain alcohol dehydrogenases
- Rhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 /
NCIB 8253 / DSM158)
Length = 247
Score = 60.9 bits (141), Expect = 3e-08
Identities = 50/163 (30%), Positives = 76/163 (46%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVES 303
R + +TG SG+G A + AREG T+A + + E A ++ H F LDVT +
Sbjct: 8 RKIVITGAGSGIGRESARQFAREG-ATLALIDRD-EAAAQVTADETGGHVFALDVTDEAA 65
Query: 304 VQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISA 483
V+ L ++N+AG++T+ + + V VNL G V A
Sbjct: 66 VETVVGRAAEALGG-----IDGLLNSAGILTMKTVDDIGVEEFRRVVDVNLTGTFLVCQA 120
Query: 484 FLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKS 612
LP +RK +PK I+N+ S L P +AY+ASK+
Sbjct: 121 ALPWLRK-------EPKAAIVNIASAQALLPSLTGSAYAASKA 156
>UniRef50_Q1WVR8 Cluster: Short chain dehydrogenase; n=1;
Lactobacillus salivarius subsp. salivarius UCC118|Rep:
Short chain dehydrogenase - Lactobacillus salivarius
subsp. salivarius (strain UCC118)
Length = 282
Score = 60.9 bits (141), Expect = 3e-08
Identities = 49/163 (30%), Positives = 78/163 (47%), Gaps = 1/163 (0%)
Frame = +1
Query: 127 LVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESV 306
+V VTG G+G+ I + G + E AAK EKL A +++
Sbjct: 5 VVIVTGASKGIGFETVLAALNNDMIVV-GTSRTPEKLAAKVQEKLPAKVDNFTAMKMDFN 63
Query: 307 QEFRKYVLTVLKDNPKY-KFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISA 483
+E K V++ + K+ + +VNNAG +G +E M + + + VN+ G M + A
Sbjct: 64 EESIKQVVSEVI--AKFGRIDVLVNNAGYAILGAFEDMDMAEVRTNFDVNVFGLMSMTQA 121
Query: 484 FLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKS 612
LP++RK + RIIN+ S G P+ + YSASK+
Sbjct: 122 VLPQMRK-------QKSGRIINLSSISGSVTGPSQSIYSASKA 157
>UniRef50_Q1DE83 Cluster: Oxidoreductase, short chain
dehydrogenase/reductase family; n=2; Myxococcus xanthus
DK 1622|Rep: Oxidoreductase, short chain
dehydrogenase/reductase family - Myxococcus xanthus
(strain DK 1622)
Length = 275
Score = 60.9 bits (141), Expect = 3e-08
Identities = 57/165 (34%), Positives = 77/165 (46%)
Frame = +1
Query: 115 SVSRLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTR 294
S +V +TG SG+G A A L+ G I + +E A L LDVT+
Sbjct: 4 SQGSVVLITGASSGIGKACAELLSARGHIVYGTSRRPVEA-APPGYRML-----ELDVTQ 57
Query: 295 VESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRV 474
+SVQ + V TVL + + + VVNNAG G E + + + N LGA+RV
Sbjct: 58 DDSVQ---RAVATVL--SREGRIDVVVNNAGHALAGAAEDTSIEEARAQLDANFLGALRV 112
Query: 475 ISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
A LP +R+ + RII V S G LP + YSASK
Sbjct: 113 CKAVLPSMRE-------RRAGRIIQVSSLGGQVGLPFQSLYSASK 150
>UniRef50_Q0BWW4 Cluster: Oxidoreductase, short chain
dehydrogenase/reductase family; n=1; Hyphomonas
neptunium ATCC 15444|Rep: Oxidoreductase, short chain
dehydrogenase/reductase family - Hyphomonas neptunium
(strain ATCC 15444)
Length = 294
Score = 60.9 bits (141), Expect = 3e-08
Identities = 45/169 (26%), Positives = 77/169 (45%)
Frame = +1
Query: 103 VSAMSVSRLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPL 282
++A +++R + VTG +G+G A A +A G+ AG+ + A + L
Sbjct: 4 LTAPALARSLLVTGASTGIGEAAARHMAARGWTVFAGVRSEKDASALRQGAAGDLRPIIL 63
Query: 283 DVTRVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLG 462
DVT+ E V+ + T L + + ++NNAG+ +G E+ VN+ G
Sbjct: 64 DVTKPEQVEGAVATISTALGNR---RLSGLLNNAGIAKMGPLAIQPLEDFEAHFTVNVFG 120
Query: 463 AMRVISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
+RV AF+P + + RI+ + S G P AY+A+K
Sbjct: 121 MLRVTQAFVPLLGGDPAREGA--PGRIVTITSVGGKIAAPFLGAYTATK 167
>UniRef50_A5WC68 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Psychrobacter sp. PRwf-1|Rep: Short-chain
dehydrogenase/reductase SDR - Psychrobacter sp. PRwf-1
Length = 309
Score = 60.9 bits (141), Expect = 3e-08
Identities = 50/173 (28%), Positives = 89/173 (51%), Gaps = 3/173 (1%)
Frame = +1
Query: 100 IVSAMSVSRLVAVTGCDSGLGWAVAARLAREGF-ITIAGMH-KGI-ETEAAKALEKLCAH 270
+++ + A+TG SG+G A+A LA+ G + ++ ++ K + ETE ++
Sbjct: 9 VITHFYQGHVAAITGAGSGIGRALALNLAQAGCNLALSDINAKNLAETEQLLKPFEIKIT 68
Query: 271 TFPLDVTRVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHV 450
T LDV+ ++V + +V+ +D+ + F + NNAGV E + IE + +
Sbjct: 69 TQALDVSDKQAVFGWADHVM---QDHTQVNF--IFNNAGVALSSTVEGESIEDIEWVMGI 123
Query: 451 NLLGAMRVISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
N G + AFLP I+++ + + IIN+ S G+ PA +AY+ASK
Sbjct: 124 NFWGMVYGTKAFLPLIKQSMQQAGNAKHGHIINISSLFGIIAQPAQSAYNASK 176
>UniRef50_Q3AXB5 Cluster: Oxidoreductase; n=4; Synechococcus|Rep:
Oxidoreductase - Synechococcus sp. (strain CC9902)
Length = 275
Score = 60.5 bits (140), Expect = 3e-08
Identities = 50/162 (30%), Positives = 69/162 (42%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVES 303
R V +TG SG+G A L +G+ A + A L++ A PLDV +S
Sbjct: 6 RTVLITGASSGIGCVTAHLLLDQGWNVFAAARR---QGAMDELQRRGAVVLPLDVADAQS 62
Query: 304 VQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISA 483
R+ + + D + A+VNNAG VG E M S VN+ G M +
Sbjct: 63 ----REDLAAEIHDRTGGRLDALVNNAGYGEVGPMETMALERARSMFEVNVFGLMGLTQL 118
Query: 484 FLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
LP +R + + RI+NV S G P Y ASK
Sbjct: 119 VLPAMR-------DRRRGRIVNVSSIAGRFATPGAGWYCASK 153
>UniRef50_Q12HC0 Cluster: Short-chain dehydrogenase/reductase SDR
precursor; n=23; Bacteria|Rep: Short-chain
dehydrogenase/reductase SDR precursor - Polaromonas sp.
(strain JS666 / ATCC BAA-500)
Length = 284
Score = 60.5 bits (140), Expect = 3e-08
Identities = 47/165 (28%), Positives = 80/165 (48%), Gaps = 1/165 (0%)
Frame = +1
Query: 118 VSRLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRV 297
++++ VTG SG+G A RL++ G+ +G + ++ E L PLDVT+
Sbjct: 4 MNKIALVTGASSGIGEVTAQRLSKAGYKVYGTSRRGGQA-GQQSFEML-----PLDVTKN 57
Query: 298 ESVQEFRKYVLTVLKDNPKYKFHAVVNNAGV-MTVGKYEWMTASMIESPVHVNLLGAMRV 474
ESV+ + ++ + + + +VNNAG + E + +S N G +R+
Sbjct: 58 ESVEAAVQKLMQL-----EGRIDLLVNNAGFGVAAAGAEESSIEQAQSMFDTNFFGIVRM 112
Query: 475 ISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
A +P +R+ RIIN+GS G P+P A Y+A+K
Sbjct: 113 TRAVVPHMRRQG-------SGRIINIGSVFGFLPMPYMALYAATK 150
>UniRef50_A6F0V6 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Marinobacter algicola DG893|Rep: Short-chain
dehydrogenase/reductase SDR - Marinobacter algicola
DG893
Length = 256
Score = 60.5 bits (140), Expect = 3e-08
Identities = 44/161 (27%), Positives = 73/161 (45%), Gaps = 1/161 (0%)
Frame = +1
Query: 130 VAVTGCDSGLGWAVAARLAREG-FITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESV 306
+ +TG +G+G A A G F+ A + L C T +DV SV
Sbjct: 5 IFITGAGAGIGRETARLFASRGWFVGAADRDEAALASLGSELGDECCSTHIIDVVDEASV 64
Query: 307 QEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAF 486
++ L + + NNAG++ VG +E ++ + + V VN++G M V+ A
Sbjct: 65 RQG----LADFASRTGGQLRLLHNNAGILKVGPFEEISLAAHRAVVEVNVIGLMTVLHAA 120
Query: 487 LPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
P ++ T P +++N+ S +P FA+YSASK
Sbjct: 121 FPYLKAT-------PGAQVVNMSSASAAYGIPDFASYSASK 154
>UniRef50_A4BGV8 Cluster: Short chain dehydrogenase; n=1; Reinekea
sp. MED297|Rep: Short chain dehydrogenase - Reinekea sp.
MED297
Length = 271
Score = 60.5 bits (140), Expect = 3e-08
Identities = 51/164 (31%), Positives = 82/164 (50%), Gaps = 3/164 (1%)
Frame = +1
Query: 130 VAVTGCDSGLGWAVAARLAREGF-ITIAGMHKGIETEAAKALEKLCAHTFPL--DVTRVE 300
+ +TG SGLG A+A R A+ G I + ++ A + L++L A F + DVT
Sbjct: 4 LVITGGASGLGLAMAQRWAKTGTNICLIDRNEDGAEFALQKLQRLGATAFFICCDVTDDN 63
Query: 301 SVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVIS 480
+V V L ++N+AGV T G E + + + +++NL+G +RV
Sbjct: 64 AVAAMAAKVKQQLGT-----IDILINSAGVPTAGSIEAESIDVWQWVLNINLMGTVRVTK 118
Query: 481 AFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKS 612
A P +R+ + K IINV S GL P+P +Y+A+K+
Sbjct: 119 ALGPLMRQ-------QGKGHIINVASQAGLTPMPMMGSYNATKA 155
>UniRef50_A7DQK3 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Candidatus Nitrosopumilus maritimus SCM1|Rep:
Short-chain dehydrogenase/reductase SDR - Candidatus
Nitrosopumilus maritimus SCM1
Length = 264
Score = 60.5 bits (140), Expect = 3e-08
Identities = 53/166 (31%), Positives = 69/166 (41%), Gaps = 3/166 (1%)
Frame = +1
Query: 121 SRLVAVTGCDSGLGWAVAARLAREGF-ITIAGMHKGIETEAAKALEKLCAHTF--PLDVT 291
++ V +TG SG+G A A+ G I + K E A LEK TF DV+
Sbjct: 5 NKTVLITGASSGIGKQTAIEFAKLGANIILVARRKEKLDELASELEKFKVTTFVCKCDVS 64
Query: 292 RVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMR 471
V+E K VL +VNNAG G + ++ IES + N G M
Sbjct: 65 DKTQVKEMSKTVLEKFDS-----VDVLVNNAGFAIYGSVKDLSVDEIESQMETNYFGMMY 119
Query: 472 VISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
I FLP + K I+NV S LP A+Y ASK
Sbjct: 120 CIKNFLPSM-------LDKKSGHIVNVASVAASFGLPGIASYCASK 158
>UniRef50_Q9BPW9 Cluster: Dehydrogenase/reductase SDR family member
9 precursor; n=29; Tetrapoda|Rep:
Dehydrogenase/reductase SDR family member 9 precursor -
Homo sapiens (Human)
Length = 319
Score = 60.5 bits (140), Expect = 3e-08
Identities = 40/128 (31%), Positives = 61/128 (47%), Gaps = 1/128 (0%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVES 303
+ + +TGCDSG G A ++GF IA + A KA T LDVT E+
Sbjct: 30 KYIFITGCDSGFGNLAARTFDKKGFHVIAACLTESGSTALKAETSERLRTVLLDVTDPEN 89
Query: 304 VQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTV-GKYEWMTASMIESPVHVNLLGAMRVIS 480
V+ ++V + + + ++NNAGV V +W+T P+ VNL G + V
Sbjct: 90 VKRTAQWVKNQVGEKGLW---GLINNAGVPGVLAPTDWLTLEDYREPIEVNLFGLISVTL 146
Query: 481 AFLPEIRK 504
LP ++K
Sbjct: 147 NMLPLVKK 154
>UniRef50_Q8RS26 Cluster: Benzil reductase; n=16; Bacillus cereus
group|Rep: Benzil reductase - Bacillus cereus
Length = 249
Score = 60.1 bits (139), Expect = 4e-08
Identities = 46/167 (27%), Positives = 81/167 (48%), Gaps = 4/167 (2%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTF--PLDVTRV 297
R V +TG GLG A+A +L E T+ + + E K E+ ++ LD+ V
Sbjct: 2 RYVIITGTSQGLGEAIATQLLEES-TTVISISRRENRELTKLAEQYNSNCIFHSLDLQDV 60
Query: 298 ESVQ-EFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGK-YEWMTASMIESPVHVNLLGAMR 471
+++ F++ + ++ KDN H ++NNAG + K E + + VH+NLL M
Sbjct: 61 HNLETNFKEIISSIKKDNVS-SIH-LINNAGTVAPMKPIEKAESEQFITNVHINLLAPMI 118
Query: 472 VISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKS 612
+ S F+ ++ ++ R+IN+ S G P + AY +K+
Sbjct: 119 LTSTFMKHTKEWKVD------KRVINISSGAGKNPYFGWGAYCTTKA 159
>UniRef50_Q0AQK5 Cluster: Short-chain dehydrogenase/reductase SDR
precursor; n=5; Bacteria|Rep: Short-chain
dehydrogenase/reductase SDR precursor - Maricaulis maris
(strain MCS10)
Length = 277
Score = 60.1 bits (139), Expect = 4e-08
Identities = 54/175 (30%), Positives = 82/175 (46%), Gaps = 3/175 (1%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREG--FITIAGMHKGIETEAAKALEKLCA-HTFPLDVTR 294
R +TG SG+G A+AA LA G I + G++ AA CA TF +D+
Sbjct: 10 RTALITGAASGIGAALAAGLAARGASLILVDINADGLDGVAAPLRADGCAVSTFVVDMAD 69
Query: 295 VESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRV 474
++ K V + H + NNAG+ G +E + + E + +NL G +R+
Sbjct: 70 AAAIARLAKDV-----EASGAPVHLLFNNAGIALGGMFEDVEMADFERLIDINLYGVIRM 124
Query: 475 ISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKSWPFGVDTMS 639
AFLP +R A++ + I+N+ S G+ AAYS +K FGV S
Sbjct: 125 SRAFLPRMR--AVD-----EAHIVNISSIFGIVAPAGQAAYSTAK---FGVKGFS 169
>UniRef50_Q07KD0 Cluster: Short-chain dehydrogenase/reductase SDR
precursor; n=1; Rhodopseudomonas palustris BisA53|Rep:
Short-chain dehydrogenase/reductase SDR precursor -
Rhodopseudomonas palustris (strain BisA53)
Length = 283
Score = 60.1 bits (139), Expect = 4e-08
Identities = 48/164 (29%), Positives = 75/164 (45%), Gaps = 2/164 (1%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREG--FITIAGMHKGIETEAAKALEKLCAHTFPLDVTRV 297
++V +TG SG+G A+A R A EG I G++ L DVT
Sbjct: 7 KVVVITGAASGIGRALAVRFAAEGARLALIDHDESGLDETGRGCLGASAIELRRSDVTAR 66
Query: 298 ESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVI 477
++V++ V++ V+NNAGV + G + + + VN G +
Sbjct: 67 DAVEQAAHAVVSCFGG-----VDIVINNAGVSSAGMIGEIGYDTLRWTMEVNFWGVVHGT 121
Query: 478 SAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
AFLP +R ++P+ ++NV S GL +PA +AY ASK
Sbjct: 122 MAFLPHLR-------ARPEAHLVNVSSVYGLIGVPAQSAYCASK 158
>UniRef50_A7IEU0 Cluster: Short-chain dehydrogenase/reductase SDR;
n=2; Alphaproteobacteria|Rep: Short-chain
dehydrogenase/reductase SDR - Xanthobacter sp. (strain
Py2)
Length = 269
Score = 60.1 bits (139), Expect = 4e-08
Identities = 50/163 (30%), Positives = 74/163 (45%), Gaps = 1/163 (0%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREGF-ITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVE 300
R V +TG SG+G A+A A G + + G +G + A AL PL ++
Sbjct: 10 RRVLITGAGSGIGRALALEAAARGMEVALCGRRRGALEDTAAALPPGAR---PLVISADI 66
Query: 301 SVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVIS 480
+ R ++ +K H +VNNAGV+ G E + +E N+L M +
Sbjct: 67 TSTADRARIVARIKAEWG-ALHVLVNNAGVVEGGPLETFDDAALEDTFRTNVLAPMALTR 125
Query: 481 AFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
P + ++P R++NVGS G P FAAYSASK
Sbjct: 126 DLAPLL------AAARPS-RVVNVGSVFGDIAYPGFAAYSASK 161
>UniRef50_A6EJ86 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Pedobacter sp. BAL39|Rep: Short-chain
dehydrogenase/reductase SDR - Pedobacter sp. BAL39
Length = 287
Score = 60.1 bits (139), Expect = 4e-08
Identities = 51/164 (31%), Positives = 77/164 (46%), Gaps = 2/164 (1%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREGFITIAGMHK--GIETEAAKALEKLCAHTFPLDVTRV 297
++V +TG +SG GW A +A G A M G + AKAL ++ A+ LDVT
Sbjct: 4 KVVLITGTNSGFGWLTANSVAALGHKVYATMRDTAGKNADKAKALAQV-ANVTVLDVTLT 62
Query: 298 ESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVI 477
+ + + TV+ +VNNAG+ G E T + ++ VN++ R++
Sbjct: 63 DETS-VKNAIDTVIATEGT--IDVLVNNAGISMFGVAESATPADVQRMFDVNVIAPWRLM 119
Query: 478 SAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
LP +RK + + IINV S G P A Y+ASK
Sbjct: 120 KLALPAMRK-------QSEGLIINVSSGWGRFSAPFSAVYAASK 156
>UniRef50_A4WGJ7 Cluster: Short-chain dehydrogenase/reductase SDR
precursor; n=1; Enterobacter sp. 638|Rep: Short-chain
dehydrogenase/reductase SDR precursor - Enterobacter sp.
638
Length = 242
Score = 60.1 bits (139), Expect = 4e-08
Identities = 51/164 (31%), Positives = 73/164 (44%), Gaps = 2/164 (1%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREGF--ITIAGMHKGIETEAAKALEKLCAHTFPLDVTRV 297
R+ VTG SG+G A+A LA G + +A + I+ A++ A DVT
Sbjct: 8 RVAVVTGASSGIGEALARELAGNGIQVVLLARRFERIDVLASELGHGAIA--IKADVTDR 65
Query: 298 ESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVI 477
ES+ V L ++NNAGVM G ++ V NLLGAM V
Sbjct: 66 ESIVAAANQVEQTLGG-----VDILINNAGVMLTGPFDSSQLDEHRQMVETNLLGAMTVT 120
Query: 478 SAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
FLP++R+ K ++N+ S G FA Y+A+K
Sbjct: 121 EVFLPQLRRN--------KGDLVNISSVAGRVAPSGFAVYAATK 156
>UniRef50_Q6RH38 Cluster: 17b-hydroxysteroid dehydrogenase type I;
n=3; Elopocephala|Rep: 17b-hydroxysteroid dehydrogenase
type I - Anguilla japonica (Japanese eel)
Length = 293
Score = 59.7 bits (138), Expect = 6e-08
Identities = 49/169 (28%), Positives = 81/169 (47%), Gaps = 7/169 (4%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREGFITI---AGMHKGIETEA----AKALEKLCAHTFPL 282
R+V +TGC SG+G ++A ++A + T A M + E K K +
Sbjct: 4 RVVLITGCSSGIGLSLAVQMASDPAKTYKVYASMRNLAKKERLLEYVKGFHKDTLDIIQM 63
Query: 283 DVTRVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLG 462
DVT +S+Q+ ++ + + + +V NAGV +G E ++ + + VNLLG
Sbjct: 64 DVTDQQSIQDAKEKIT-------ENRVDILVCNAGVGLMGPLETLSQDTMRQILDVNLLG 116
Query: 463 AMRVISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
+R I FLP ++ ++ + ++ GS GLQ LP Y ASK
Sbjct: 117 TIRTIQTFLPGMK-------TRRRGHVLVTGSIGGLQGLPFNELYCASK 158
>UniRef50_Q127D6 Cluster: Short-chain dehydrogenase/reductase SDR
precursor; n=6; Proteobacteria|Rep: Short-chain
dehydrogenase/reductase SDR precursor - Polaromonas sp.
(strain JS666 / ATCC BAA-500)
Length = 268
Score = 59.7 bits (138), Expect = 6e-08
Identities = 53/166 (31%), Positives = 72/166 (43%)
Frame = +1
Query: 112 MSVSRLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVT 291
MS S +V VTG SG+G A + AR G + G + I AKA +DV
Sbjct: 1 MSKSIVVVVTGVSSGIGRVAAEKFARRG-CQVFGTVRSI----AKAKPMSGVELIEMDVR 55
Query: 292 RVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMR 471
SVQ + ++ + +VNNAG+ +G E T S N+ G +R
Sbjct: 56 DDASVQRAIQSIIDQVG-----CIDVLVNNAGMNMIGAVEETTTGEAASLFDTNVFGILR 110
Query: 472 VISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
A LP +R ++ RI+NV S G P P YSASK
Sbjct: 111 TTQAVLPHMR-------AQHHGRIVNVSSVLGFLPAPYMGLYSASK 149
>UniRef50_A6FXI4 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Plesiocystis pacifica SIR-1|Rep: Short-chain
dehydrogenase/reductase SDR - Plesiocystis pacifica
SIR-1
Length = 266
Score = 59.7 bits (138), Expect = 6e-08
Identities = 49/161 (30%), Positives = 70/161 (43%), Gaps = 1/161 (0%)
Frame = +1
Query: 130 VAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESVQ 309
V +TG G+G A A G G +AA A E H +DV ESV
Sbjct: 15 VFITGAARGIGLACARAFVEAGAHVGVCDRDGEALDAA-AKELAGVHAERVDVCEPESVA 73
Query: 310 EFRKYVLTVLKDNP-KYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAF 486
L D P + + +VNNAGVM VG +E + + + VN G + + A
Sbjct: 74 R----ALAAFVDGPGRGRLDVLVNNAGVMHVGPFEAVPLAAHHQTIAVNFQGLLNLCHAA 129
Query: 487 LPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
P + +T P R+IN+ S + +P A+YSA+K
Sbjct: 130 FPHLAQT-------PGARLINMSSASAIHGIPEMASYSATK 163
>UniRef50_A4A7Q2 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Congregibacter litoralis KT71|Rep: Short-chain
dehydrogenase/reductase SDR - Congregibacter litoralis
KT71
Length = 277
Score = 59.7 bits (138), Expect = 6e-08
Identities = 50/161 (31%), Positives = 74/161 (45%), Gaps = 1/161 (0%)
Frame = +1
Query: 130 VAVTGCDSGLGWAVAARLA-REGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESV 306
+ +TG +G+G A A LA ++ + AG + E E + A +DVT +SV
Sbjct: 4 IVITGATAGIGRAAAILLASKKHRVFAAGRDEAALAELDAGYENITA--LAMDVTDGDSV 61
Query: 307 QEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAF 486
V L +VNNAG VG E + + E N+LG +RV AF
Sbjct: 62 TAAAARVFDALDGKAP---DVLVNNAGYAVVGPLEAVPDAEWERQFSTNVLGLVRVTRAF 118
Query: 487 LPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
+P +R+ + + RIINV S G LP F Y+++K
Sbjct: 119 VPGMRE-------RRRGRIINVSSVAGRVTLPFFGPYNSTK 152
>UniRef50_Q8NEX9 Cluster: Retinol dehydrogenase similar protein;
n=8; Eutheria|Rep: Retinol dehydrogenase similar protein
- Homo sapiens (Human)
Length = 313
Score = 59.7 bits (138), Expect = 6e-08
Identities = 49/173 (28%), Positives = 81/173 (46%), Gaps = 1/173 (0%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVES 303
+ V +TGCDSG G +A +L G +A ++ + T LDVT+ ES
Sbjct: 26 KYVFITGCDSGFGNLLAKQLVDRGMQVLAACFTEEGSQKLQRDTSYRLQTTLLDVTKSES 85
Query: 304 VQEFRKYVLTVLKDNPKYKFHAVVNNAGV-MTVGKYEWMTASMIESPVHVNLLGAMRVIS 480
++ ++V + + + A+VNNAGV + G EW+T ++VNL+G + V
Sbjct: 86 IKAAAQWVRDKVGEQGLW---ALVNNAGVGLPSGPNEWLTKDDFVKVINVNLVGLIEVTL 142
Query: 481 AFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKSWPFGVDTMS 639
LP +++ + R++N+ S G + Y SK FGV+ S
Sbjct: 143 HMLPMVKRA--------RGRVVNMSSSGGRVAVIG-GGYCVSK---FGVEAFS 183
>UniRef50_UPI0000E46C37 Cluster: PREDICTED: hypothetical protein;
n=2; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 304
Score = 59.3 bits (137), Expect = 8e-08
Identities = 47/170 (27%), Positives = 79/170 (46%), Gaps = 8/170 (4%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREG------FITIAGMHK--GIETEAAKALEKLCAHTFP 279
++ +TGC SG+G +AA+L ++ + T+ + K ++T A AL+ P
Sbjct: 4 KVALITGCSSGIGLNIAAKLGKDAAKKYMVYSTMRNLGKKEALQTAAGDALDDTI-FIRP 62
Query: 280 LDVTRVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLL 459
LDV +SV ++ + + V+NNAG+ T E+ S + N
Sbjct: 63 LDVVNDDSVTNAVNEIV-----DKHGRIDLVINNAGIATFSPLEYTPLSDVRDVFETNFF 117
Query: 460 GAMRVISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
G +R++ A LP +++ + IINV S G+ P + YSASK
Sbjct: 118 GVVRMMQAVLPHMKE-------QRSGHIINVSSIGGVLGHPFYETYSASK 160
>UniRef50_Q4JV39 Cluster: Putative dehydrogenase related to
short-chain alcohol dehydrogenases; n=1; Corynebacterium
jeikeium K411|Rep: Putative dehydrogenase related to
short-chain alcohol dehydrogenases - Corynebacterium
jeikeium (strain K411)
Length = 279
Score = 59.3 bits (137), Expect = 8e-08
Identities = 50/170 (29%), Positives = 81/170 (47%), Gaps = 6/170 (3%)
Frame = +1
Query: 136 VTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALE-KLCAHTFP----LDVTRVE 300
VTG SG+G VA +LA G+ +A + E A A + C T +DVT VE
Sbjct: 5 VTGAASGIGREVALQLAERGY-AVAISDRDAEGLATTASDITTCGGTVADQRTVDVTDVE 63
Query: 301 SVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVIS 480
+V+ + V+ P H AG+ G M + + VNL+G++ ++
Sbjct: 64 AVKAWADDVVAT-HGAPDQVHHV----AGIAIWGDVRQMPHEKWQRVIDVNLMGSVHMVE 118
Query: 481 AFLPEIRKT-AIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKSWPFGV 627
AF P++ ++ + + + +++ V S G+ LP AAYSASK G+
Sbjct: 119 AFAPKLMESQPVRRRRRDRRKLVFVSSAAGIIGLPWHAAYSASKGGVLGM 168
>UniRef50_Q3IU31 Cluster: Probable dehydrogenase/ reductase 4; n=1;
Natronomonas pharaonis DSM 2160|Rep: Probable
dehydrogenase/ reductase 4 - Natronomonas pharaonis
(strain DSM 2160 / ATCC 35678)
Length = 253
Score = 59.3 bits (137), Expect = 8e-08
Identities = 55/164 (33%), Positives = 77/164 (46%), Gaps = 4/164 (2%)
Frame = +1
Query: 130 VAVTGCDSGLGWAVAARLAREG-FITIAGMHKGIETEAAKALEKL--CAHTFPLDVTRVE 300
V +TG SG+G A A ++AREG F+ +++ E A+E A LDVT
Sbjct: 8 VFITGAGSGIGRATALKVAREGAFVVATDINEDGGRETVDAVEDAGGDAAFHELDVT--- 64
Query: 301 SVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKY-EWMTASMIESPVHVNLLGAMRVI 477
EF+ V T + Y A++NNAGV Y E +T + E + VNL G
Sbjct: 65 DADEFKAVVETAADE---YGLDAMINNAGVGHPPAYTEDVTETTFEYVLDVNLRGVWNGC 121
Query: 478 SAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
A LP ++ S+ + I+NVGS LP A YS +K
Sbjct: 122 QAALPHLK-------SQGEGAIVNVGSLASFLGLPKQAVYSLTK 158
>UniRef50_A7DJ01 Cluster: Short-chain dehydrogenase/reductase SDR;
n=2; Methylobacterium extorquens PA1|Rep: Short-chain
dehydrogenase/reductase SDR - Methylobacterium
extorquens PA1
Length = 247
Score = 58.8 bits (136), Expect = 1e-07
Identities = 53/172 (30%), Positives = 78/172 (45%), Gaps = 1/172 (0%)
Frame = +1
Query: 112 MSVSRLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIET-EAAKALEKLCAHTFPLDV 288
+ RLV VTG GLG A+A LA +GF +A + E EAA+ D+
Sbjct: 5 LKTGRLVVVTGASRGLGLAMAETLAADGFRVVALARRPSEALEAAQVAAPGRIAFMAADL 64
Query: 289 TRVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAM 468
++++Q + + + P Y +VNNA + T G M AS I VH+N L M
Sbjct: 65 GEIDALQALAQRIRA--EHGPVY---GLVNNAALGTPGLLTTMPASKIAELVHLNTLAPM 119
Query: 469 RVISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKSWPFG 624
V++ +L TA RI+NV S A + Y+A+K+ G
Sbjct: 120 -VLTKYLARGMMTA------GAGRIVNVSSVIAFTGYNALSVYAATKASMIG 164
>UniRef50_Q20840 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 305
Score = 58.8 bits (136), Expect = 1e-07
Identities = 49/164 (29%), Positives = 78/164 (47%), Gaps = 2/164 (1%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFP-LDVTRVE 300
+ VA++GCDSG G +A RL ++G + K + T + TF L+V E
Sbjct: 20 KTVAISGCDSGFGRLLAVRLVKQGVPNGESLKKEVNTPSLL--------TFGILNVANDE 71
Query: 301 SVQEFRKYVLTVLKDNPKYKFHAVVNNAGVM-TVGKYEWMTASMIESPVHVNLLGAMRVI 477
SV+EF K V +++ + VV NAG++ G +W++A + + VN G MR
Sbjct: 72 SVKEFVKLVEKTVENRGLW---GVVANAGILGNSGPDDWLSAQDYINTMQVNTFGVMR-- 126
Query: 478 SAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
F+ ++K K + R++ + S G P P Y SK
Sbjct: 127 --FIQGLKK----FVKKQEGRVVIISSISGRTPRPTVGPYCVSK 164
>UniRef50_Q6MRN8 Cluster: Putative oxidoreductase; n=1; Bdellovibrio
bacteriovorus|Rep: Putative oxidoreductase -
Bdellovibrio bacteriovorus
Length = 308
Score = 58.4 bits (135), Expect = 1e-07
Identities = 53/167 (31%), Positives = 77/167 (46%), Gaps = 6/167 (3%)
Frame = +1
Query: 127 LVAVTGCDSGLGWAVAARLAR--EGFITIAGMHKGIETEAAKALEKLCAHTFPLDVT--- 291
+V VTGC +G+G AVA L R E + + K ++ + LE PLDVT
Sbjct: 19 VVLVTGCSAGIGLAVAHLLRRHPEYRLVLTAREKSLDKLRDEFLEDERLLIRPLDVTSEA 78
Query: 292 -RVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAM 468
R++ V E K + ++NNAG+ E MT E + N G M
Sbjct: 79 DRIQLVNEVSKVWGGI---------DILINNAGISYRAVVEHMTEKDEELQMATNYFGPM 129
Query: 469 RVISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
+I LP +R+T + +IINV S G+ +P ++YSASK
Sbjct: 130 GLIRLCLPHMRETG-------RGKIINVSSVSGMLAMPTMSSYSASK 169
>UniRef50_A3HAH4 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Caldivirga maquilingensis IC-167|Rep: Short-chain
dehydrogenase/reductase SDR - Caldivirga maquilingensis
IC-167
Length = 248
Score = 58.4 bits (135), Expect = 1e-07
Identities = 53/167 (31%), Positives = 76/167 (45%), Gaps = 4/167 (2%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAH--TFPLDVTRV 297
++ VTG G+G +A RLAR+G I +A G E E A+ + KL LDVT
Sbjct: 7 KVAIVTGAGQGIGRGIALRLARDGAIVVATDITGKENEVAEEVRKLGGQGMALRLDVTDG 66
Query: 298 ESVQEFRKYVLTVLKDNPKY-KFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRV 474
+ +E + V KY +VNNAG+ + MT + ++VNL G V
Sbjct: 67 KMAEEVARTVF------DKYGHIDILVNNAGIYPFKPFMEMTFNDWYRVINVNLNGVFNV 120
Query: 475 ISAFLPEIRKTAIETTSKPKPRIINVGSHCG-LQPLPAFAAYSASKS 612
A +P + K + RIIN+ S G + YSASK+
Sbjct: 121 TRAVVPYMVK-------QKNGRIINIASIAGAVMGFMGLTHYSASKA 160
>UniRef50_Q0S388 Cluster: Possible dehydrogenase; n=16;
Corynebacterineae|Rep: Possible dehydrogenase -
Rhodococcus sp. (strain RHA1)
Length = 664
Score = 58.0 bits (134), Expect = 2e-07
Identities = 59/171 (34%), Positives = 83/171 (48%), Gaps = 6/171 (3%)
Frame = +1
Query: 118 VSRLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLC---AHTFPLDV 288
V R V +TG SG+G + A AR+G I + E +A A + A+ +P D+
Sbjct: 364 VGRHVVITGASSGIGRSSAIATARKGAKVILLARRTEELDAVVAEIRAAGGDAYGYPCDI 423
Query: 289 TRVESVQEFRKYVLTVLKDNPKYKFHAVVNNAG-VMTVGKYEWM-TASMIESPVHVNLLG 462
T ESV+ K VL D+ +VNNAG + G Y E + VN G
Sbjct: 424 TDDESVEHTVKAVLAE-HDH----VDMLVNNAGRSIRRGLYNSTDRLHDFERTMAVNYFG 478
Query: 463 AMRVISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQ-PLPAFAAYSASKS 612
A+R++ AFLP++R + I+N+ S G+Q P FAAY ASKS
Sbjct: 479 AVRLVLAFLPQMR-------DRRFGHIVNISS-AGVQGATPRFAAYVASKS 521
>UniRef50_Q0RXI5 Cluster: Probable short-chain dehydrogenase; n=1;
Rhodococcus sp. RHA1|Rep: Probable short-chain
dehydrogenase - Rhodococcus sp. (strain RHA1)
Length = 552
Score = 58.0 bits (134), Expect = 2e-07
Identities = 52/171 (30%), Positives = 76/171 (44%), Gaps = 4/171 (2%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCA--HTFP-LDVT- 291
R V +TG +G+G A A R A +G+ A +++ A L HT+ LDVT
Sbjct: 300 RTVVITGAGAGIGRAAARRFAAKGWTLCA---TDVDSSALDELRADLGDQHTYASLDVTD 356
Query: 292 RVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMR 471
+ E + F ++ F +VNNAGV + K+E MT E VN+ G +
Sbjct: 357 KAEIARVFAEFAAA-----HGGSFEVLVNNAGVAFIDKFEDMTLEQHELITRVNVNGVLN 411
Query: 472 VISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKSWPFG 624
P + KT ++IN+ S +P+ A YSASK W G
Sbjct: 412 CTYLAFPHLSKTG-------DAKVINMCSLSAEYGVPSEATYSASKFWVRG 455
>UniRef50_Q08T77 Cluster: Oxidoreductase; n=1; Stigmatella
aurantiaca DW4/3-1|Rep: Oxidoreductase - Stigmatella
aurantiaca DW4/3-1
Length = 300
Score = 58.0 bits (134), Expect = 2e-07
Identities = 55/171 (32%), Positives = 77/171 (45%), Gaps = 2/171 (1%)
Frame = +1
Query: 103 VSAMSVSRLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPL 282
+S S+ + V +TGC +G G A A A +G+ IA M + AL +
Sbjct: 15 LSVWSMKKTVLITGCSTGFGLASAKHFAAQGWNVIATMRTPSPEQELVALPGVL------ 68
Query: 283 DVTRVESVQEFRKYVLTVLKDNPKY--KFHAVVNNAGVMTVGKYEWMTASMIESPVHVNL 456
VTR++ VQ+ R + + LK + AVVNNAG G +E I VN+
Sbjct: 69 -VTRLD-VQD-RTSIDSALKVGVERFGGLDAVVNNAGFGLHGLFESTPREKILEQFEVNV 125
Query: 457 LGAMRVISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
G M VI A LP + + I+NV S G+ LP + Y ASK
Sbjct: 126 FGVMDVIRAALPYF-------VQRGEGAIVNVSSGAGVFTLPMISLYCASK 169
>UniRef50_Q07WY7 Cluster: Short-chain dehydrogenase/reductase SDR
precursor; n=2; Gammaproteobacteria|Rep: Short-chain
dehydrogenase/reductase SDR precursor - Shewanella
frigidimarina (strain NCIMB 400)
Length = 256
Score = 58.0 bits (134), Expect = 2e-07
Identities = 42/161 (26%), Positives = 76/161 (47%), Gaps = 1/161 (0%)
Frame = +1
Query: 130 VAVTGCDSGLGWAVAARLAREGF-ITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESV 306
+ +TG SG+G A A ++G+ + +A ++ T+A + ++ F LDV+ V
Sbjct: 6 IFITGAASGIGLATAKHFHKKGYWVGMADINLAQLTQATEIWDRTRVRLFQLDVSDFSQV 65
Query: 307 QEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAF 486
Q + + +VNNAG++ +G +E + + + VN++G M + A
Sbjct: 66 Q----HAMAKFCAEHNNCLAILVNNAGILEIGPFEDIPIEHHQRTLSVNVIGVMNLCHAA 121
Query: 487 LPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
P ++ + T IIN+ S +P A+YSASK
Sbjct: 122 WPYLKNSGTST-------IINMSSASSDYGVPELASYSASK 155
>UniRef50_A3PSV4 Cluster: Short-chain dehydrogenase/reductase SDR
precursor; n=27; cellular organisms|Rep: Short-chain
dehydrogenase/reductase SDR precursor - Mycobacterium
sp. (strain JLS)
Length = 247
Score = 58.0 bits (134), Expect = 2e-07
Identities = 48/170 (28%), Positives = 80/170 (47%), Gaps = 4/170 (2%)
Frame = +1
Query: 112 MSVSRLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIE----TEAAKALEKLCAHTFP 279
M+ S+++ VTG SG+G AVA LAR G IAG + + A LE+
Sbjct: 5 MTDSKIILVTGASSGIGAAVATHLARAGHHVIAGARREDRLRELADGAADLERGSLSVRR 64
Query: 280 LDVTRVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLL 459
LDVT E +V + + + +VNNAG+M + + + + ++ + VN+
Sbjct: 65 LDVT---DRAEMAAFVDDAVSTHG--RIDVLVNNAGIMPLSRLDALLVDQWDAMIDVNVR 119
Query: 460 GAMRVISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
G + I+A LP + + ++G+H + +P A YSA+K
Sbjct: 120 GLLNGIAAALPHFHRLG----GGHFVTVASIGAH---EVVPTSAVYSATK 162
>UniRef50_Q19246 Cluster: Dehydrogenases, short chain protein 25;
n=4; Caenorhabditis|Rep: Dehydrogenases, short chain
protein 25 - Caenorhabditis elegans
Length = 248
Score = 58.0 bits (134), Expect = 2e-07
Identities = 52/176 (29%), Positives = 83/176 (47%), Gaps = 2/176 (1%)
Frame = +1
Query: 103 VSAMSVSRLVAVTGCDSGLGWAVAARLAREGF-ITIAGMHKGIETEAAKALEKLCAH-TF 276
+SA+ R+ VTG SG+G A++ LA+ G + +A + G AKAL +H +F
Sbjct: 1 MSALLGGRIAVVTGGASGIGKAISQTLAKHGARVVVADLDSGNAAATAKALPASQSHSSF 60
Query: 277 PLDVTRVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNL 456
DV+ +SV+ ++V ++ P +VN AG+ M +S + VNL
Sbjct: 61 ACDVSNADSVKGLSEHVKSL--GTPS----ILVNCAGITKDSTLLKMKQEQWDSVIKVNL 114
Query: 457 LGAMRVISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKSWPFG 624
G V AF+ K +++ + P IINV S G Y+A+K+ G
Sbjct: 115 TGVFHVSQAFV----KASVDNNNHPL-SIINVSSIVGKMGNFGQTNYAATKAGVIG 165
>UniRef50_Q8TMH3 Cluster: 3-oxoacyl-[acyl-carrier protein]
reductase; n=4; Methanosarcina|Rep:
3-oxoacyl-[acyl-carrier protein] reductase -
Methanosarcina acetivorans
Length = 242
Score = 58.0 bits (134), Expect = 2e-07
Identities = 52/174 (29%), Positives = 80/174 (45%), Gaps = 3/174 (1%)
Frame = +1
Query: 118 VSRLVAVTGCDSGLGWAVAARLAREGF-ITIAGMHKGIETEAAKALEKLCAHTF--PLDV 288
V + VTG + G+G A+ LA+EG I IA ++ E L+ + + F P+DV
Sbjct: 10 VGQTALVTGGNKGIGRAICFALAKEGVNIIIAARNESESKETQDQLKDMGSKAFEIPVDV 69
Query: 289 TRVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAM 468
E V+ R T+ K + ++NNAGV + E T + + NL G
Sbjct: 70 RNEEDVR--RLISRTIDKCG---RLDILINNAGVALKKRLEETTVEEYDKIIDTNLKGVF 124
Query: 469 RVISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKSWPFGVD 630
+P +R++ +IIN+ S GL +P F+ Y ASK FGV+
Sbjct: 125 LCTKYAIPYLRRSK-------NGKIINISSIGGLHGIPEFSVYCASK---FGVN 168
>UniRef50_A7D324 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Halorubrum lacusprofundi ATCC 49239|Rep:
Short-chain dehydrogenase/reductase SDR - Halorubrum
lacusprofundi ATCC 49239
Length = 306
Score = 58.0 bits (134), Expect = 2e-07
Identities = 52/174 (29%), Positives = 72/174 (41%)
Frame = +1
Query: 118 VSRLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRV 297
V + V +TGC SG+G A A EG+ A + E L + LDVT
Sbjct: 10 VQKTVLITGCSSGIGRAAAHAFLDEGWTVYATARNPADIET---LGEAGCELATLDVTDQ 66
Query: 298 ESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVI 477
V +L + + AVVNNAG G E + + + VN+ G R+I
Sbjct: 67 SDVDRVVDRIL-----DEEGAIDAVVNNAGYGQFGPVEDVPTAKVHEQFDVNVYGPHRLI 121
Query: 478 SAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKSWPFGVDTMS 639
A LP +R+ T I+NV S G P YS SK F ++ +S
Sbjct: 122 KAVLPGMRRERDGT-------IVNVSSVAGRVSFPGGGVYSGSK---FAIEALS 165
>UniRef50_Q07530 Cluster: Uncharacterized oxidoreductase YDL114W;
n=2; Saccharomyces cerevisiae|Rep: Uncharacterized
oxidoreductase YDL114W - Saccharomyces cerevisiae
(Baker's yeast)
Length = 308
Score = 58.0 bits (134), Expect = 2e-07
Identities = 46/173 (26%), Positives = 76/173 (43%)
Frame = +1
Query: 106 SAMSVSRLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLD 285
S +S + +TG SGLG+ +A L+R I + T A + + D
Sbjct: 33 SILSKNATALITGGSSGLGFELAKELSRRINKVIVADIQSFPTFAQVEYNNI--FYYQCD 90
Query: 286 VTRVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGA 465
+T ++ ++ +K + + + ++NNAGV + K E MT +E + +NL+GA
Sbjct: 91 ITSLDEIKNLKKAI-----ERDHGNINIIINNAGVAHIKKLEHMTNKEVEQLIDINLIGA 145
Query: 466 MRVISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKSWPFG 624
R+IS F A + + IIN+ S G +Y ASK G
Sbjct: 146 YRIISTF-------AEDMIDNREGFIINIASVLGELTPARLTSYGASKGAMIG 191
>UniRef50_Q7D8X9 Cluster: Oxidoreductase, short-chain
dehydrogenase/reductase family; n=10; Mycobacterium
tuberculosis complex|Rep: Oxidoreductase, short-chain
dehydrogenase/reductase family - Mycobacterium
tuberculosis
Length = 302
Score = 57.6 bits (133), Expect = 2e-07
Identities = 51/165 (30%), Positives = 79/165 (47%), Gaps = 4/165 (2%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREG-FITIAGMHKGIETEAAKALEKL--CAHTFPLDVTR 294
++V +TG SG+G A A AREG + +A +G A+ +E A PLDV+
Sbjct: 10 QVVLITGASSGIGEATAKAFAREGAVVALAARREGALRRVAREIEAAGGRAMVAPLDVSS 69
Query: 295 VESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMT-ASMIESPVHVNLLGAMR 471
ESV R V V+ + + V NNAGV VG + T + ++ LG +R
Sbjct: 70 SESV---RAMVADVVGEFG--RIDVVFNNAGVSLVGPVDAETFLDDTREMLEIDYLGTVR 124
Query: 472 VISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSAS 606
V+ LP +++ + RI+N+ S G + FA YS++
Sbjct: 125 VVREVLPIMKQ-------QRSGRIMNMSSVVGRKAFARFAGYSSA 162
>UniRef50_Q1GI00 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Silicibacter sp. TM1040|Rep: Short-chain
dehydrogenase/reductase SDR - Silicibacter sp. (strain
TM1040)
Length = 277
Score = 57.6 bits (133), Expect = 2e-07
Identities = 52/165 (31%), Positives = 72/165 (43%)
Frame = +1
Query: 115 SVSRLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTR 294
S +++ VTG SG+G A RL EG+ T+ G + ++ + L H PLDVT
Sbjct: 4 SKHKVIVVTGASSGIGKTGALRLISEGY-TVYGAARSVDK--MQDLVVAGGHALPLDVTD 60
Query: 295 VESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRV 474
SV++ V VLK+ + + NNAG G E + VNL G +
Sbjct: 61 ASSVKQA---VAQVLKEQGR--IDVLWNNAGYSVAGAVEDVPLLDARQQFEVNLFGVAEI 115
Query: 475 ISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
LP++RK + IIN S G P A Y ASK
Sbjct: 116 TKTVLPQMRK-------QRSGLIINTSSVGGKVFSPLNAWYHASK 153
>UniRef50_A7HRS7 Cluster: Short-chain dehydrogenase/reductase SDR;
n=2; Alphaproteobacteria|Rep: Short-chain
dehydrogenase/reductase SDR - Parvibaculum
lavamentivorans DS-1
Length = 281
Score = 57.6 bits (133), Expect = 2e-07
Identities = 50/163 (30%), Positives = 74/163 (45%)
Frame = +1
Query: 121 SRLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVE 300
SR +TG SGLG A+A G + + + + E +AL A F LDVT
Sbjct: 5 SRKWWITGVSSGLGQAIATAALARGDMVAGTVRRKADLEVFEALAPGRALGFLLDVTDSA 64
Query: 301 SVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVIS 480
+V++ ++++ +VNNAG +G E + I + VN+ GA+ VI
Sbjct: 65 AVRK----TAAIIEERTG-GIDILVNNAGYGLIGAIEEASVEEIRAQFDVNVFGAVGVIQ 119
Query: 481 AFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
A LP +RK + I+NV S GL P Y A+K
Sbjct: 120 AALPFMRK-------RRAGHILNVTSVSGLAPWMGTGIYGATK 155
>UniRef50_Q9FJP5 Cluster: Similarity to dehydrogenase; n=9; core
eudicotyledons|Rep: Similarity to dehydrogenase -
Arabidopsis thaliana (Mouse-ear cress)
Length = 341
Score = 57.6 bits (133), Expect = 2e-07
Identities = 50/171 (29%), Positives = 81/171 (47%), Gaps = 2/171 (1%)
Frame = +1
Query: 106 SAMSVSRLVAVTGCDSG-LGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPL 282
S+ + +V +TGC G +G A+A + G +A + LEK F +
Sbjct: 3 SSSDETPVVLITGCSQGGIGHALAREFSANGCRVVATSRS---QKTMTELEK--DSKFFV 57
Query: 283 DVTRVESVQEFRKYVLTVLKDNPKY-KFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLL 459
V+S Q K V V+ K+ + +VNNAGV +G + S ++ + N+L
Sbjct: 58 QELDVQSEQSVSKVVSKVID---KFGQIDVLVNNAGVQCIGPLAEIPISAMDYTFNTNVL 114
Query: 460 GAMRVISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKS 612
G+MR+ A +P + SK K +I+N+GS + P P Y+ASK+
Sbjct: 115 GSMRMTQAVVPHM-------ASKKKGKIVNIGSISIMAPGPWAGVYTASKA 158
>UniRef50_P80365 Cluster: Corticosteroid 11-beta-dehydrogenase
isozyme 2; n=39; Euteleostomi|Rep: Corticosteroid
11-beta-dehydrogenase isozyme 2 - Homo sapiens (Human)
Length = 405
Score = 57.6 bits (133), Expect = 2e-07
Identities = 51/171 (29%), Positives = 74/171 (43%), Gaps = 7/171 (4%)
Frame = +1
Query: 121 SRLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCA---HTFPLDVT 291
+R V +TGCDSG G A +L GF +A + + + + A L C+ +D+T
Sbjct: 82 TRAVLITGCDSGFGKETAKKLDSMGFTVLATVLE-LNSPGAIELRTCCSPRLRLLQMDLT 140
Query: 292 R---VESVQEFRKYVLTVLKDNPKYKFHAVVNNAG-VMTVGKYEWMTASMIESPVHVNLL 459
+ + V EF K T +VNNAG V E + S + VN
Sbjct: 141 KPGDISRVLEFTKAHTT------STGLWGLVNNAGHNEVVADAELSPVATFRSCMEVNFF 194
Query: 460 GAMRVISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKS 612
GA+ + LP +R + + RI+ VGS G P P AY SK+
Sbjct: 195 GALELTKGLLPLLRSS--------RGRIVTVGSPAGDMPYPCLGAYGTSKA 237
>UniRef50_Q4L7K1 Cluster: Similar to 3(or 17)beta-hydroxysteroid
dehydrogenase; n=1; Staphylococcus haemolyticus
JCSC1435|Rep: Similar to 3(or 17)beta-hydroxysteroid
dehydrogenase - Staphylococcus haemolyticus (strain
JCSC1435)
Length = 285
Score = 57.2 bits (132), Expect = 3e-07
Identities = 51/173 (29%), Positives = 83/173 (47%), Gaps = 5/173 (2%)
Frame = +1
Query: 127 LVAVTGCDSGLGWAVAARLAREGFITIAGMHK-----GIETEAAKALEKLCAHTFPLDVT 291
+ VTG SGLG+ + LA +GF A M ++ EA K L LDVT
Sbjct: 5 IALVTGASSGLGFETSLMLAEKGFQVYATMRNLENQMNLKIEATKRNVDLTI--LELDVT 62
Query: 292 RVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMR 471
+++S++ ++++ + + ++NNAG E T I +++NL+G +R
Sbjct: 63 KLDSIKSAVEFII-----QEEGRIDILINNAGAGFNKTTEQATDEEINWQLNLNLMGVIR 117
Query: 472 VISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKSWPFGVD 630
+ A LP +R S+ + R+IN+ S GL P Y A+K FGV+
Sbjct: 118 MTKAVLPIMR-------SQREGRVINISSVGGLVGQPFNEIYCAAK---FGVE 160
>UniRef50_Q3WJ14 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Frankia sp. EAN1pec|Rep: Short-chain
dehydrogenase/reductase SDR - Frankia sp. EAN1pec
Length = 288
Score = 57.2 bits (132), Expect = 3e-07
Identities = 51/162 (31%), Positives = 68/162 (41%), Gaps = 1/162 (0%)
Frame = +1
Query: 130 VAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCA-HTFPLDVTRVESV 306
V V+G G+G A LA G++ A + E ++ L L +DV ESV
Sbjct: 10 VLVSGAAGGIGAATVRLLADRGYLVFAAVRA--ENHTSRVLADLSGVQVVTMDVADPESV 67
Query: 307 QEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAF 486
+ V + P AVVNNAGV+ G E + + VN G V AF
Sbjct: 68 ATAAEEVNGAV---PNGGLRAVVNNAGVIVQGPLELVPPDELRRQFEVNTFGPAYVTQAF 124
Query: 487 LPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKS 612
LP +R RIINV + P+P A SASK+
Sbjct: 125 LPMLR--------AGHGRIINVTAPTARVPMPFMAPISASKA 158
>UniRef50_Q1IPD7 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Acidobacteria bacterium Ellin345|Rep: Short-chain
dehydrogenase/reductase SDR - Acidobacteria bacterium
(strain Ellin345)
Length = 244
Score = 57.2 bits (132), Expect = 3e-07
Identities = 57/178 (32%), Positives = 80/178 (44%), Gaps = 5/178 (2%)
Frame = +1
Query: 121 SRLVAVTGCDSGLGWAVAARLAREGF-ITIAGMH-KGIETEAAKALEK--LCAHTFPLDV 288
+++ VTG G+G A+A RLA G + I H +G+ A E C P DV
Sbjct: 13 NQVSVVTGSSRGMGAAIARRLAIMGAAVVITARHAEGLSATAQSIRENGGQC-EAVPCDV 71
Query: 289 TRVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEW-MTASMIESPVHVNLLGA 465
T + V+ + V + + +VNNAG+ ++G+ W E + NL G
Sbjct: 72 TNLAQVEAVGRAV-----EKKFGRIDILVNNAGIGSMGRKLWEFPPDEWERVMSTNLRGP 126
Query: 466 MRVISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKSWPFGVDTMS 639
+I F P + I S IIN+ S G PLP AAYSASK W T+S
Sbjct: 127 YYLIRTFAPMM----IRANSG---HIINISSLAGKNPLPNGAAYSASK-WGLNGLTLS 176
>UniRef50_Q04HM4 Cluster: D-alanine transfer protein, short-chain
dehydrogenase; n=2; Oenococcus oeni|Rep: D-alanine
transfer protein, short-chain dehydrogenase - Oenococcus
oeni (strain BAA-331 / PSU-1)
Length = 263
Score = 57.2 bits (132), Expect = 3e-07
Identities = 48/167 (28%), Positives = 80/167 (47%), Gaps = 3/167 (1%)
Frame = +1
Query: 121 SRLVAVTGCDSGLGWAVAARLAR-EGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRV 297
++ + VTG SG+G A A +LA + I I K TE K + + + +DV+
Sbjct: 5 NKKIVVTGGTSGIGLAFAKKLAAIDNQIIIGSRSKEKITEVVKDNKNISG--YQVDVSDQ 62
Query: 298 ESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKY--EWMTASMIESPVHVNLLGAMR 471
ESV+ F K ++ K+ V+N+AG+M E T+ +++ + NL+G +
Sbjct: 63 ESVERFYKQTISEFKN-----IDIVINSAGIMRHYNLLDEKTTSQKLQAEIQTNLIGTIN 117
Query: 472 VISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKS 612
+ FLP +RK A + I+N+ S A YSA+K+
Sbjct: 118 IDKIFLPILRKQA-------ESMIVNISSGLANLSSAAHPIYSATKA 157
>UniRef50_A5V342 Cluster: Short-chain dehydrogenase/reductase SDR
precursor; n=1; Sphingomonas wittichii RW1|Rep:
Short-chain dehydrogenase/reductase SDR precursor -
Sphingomonas wittichii RW1
Length = 265
Score = 57.2 bits (132), Expect = 3e-07
Identities = 46/158 (29%), Positives = 62/158 (39%)
Frame = +1
Query: 136 VTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESVQEF 315
VTG GLG A+A L G I + + E EA AH LD+ +
Sbjct: 7 VTGVAGGLGQALATALLDRGDIVVGTARRVAEAEAFARSRPGAAHGIALDLDDHARIAAA 66
Query: 316 RKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAFLPE 495
+ + + VVNNAG E ++ NL G M V+ AFLP
Sbjct: 67 VEQAMALAGGG----IDVVVNNAGRSLFAPVEETPLDDAKALFATNLFGPMAVMQAFLPH 122
Query: 496 IRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
+R+ T + + S CGL +P AY ASK
Sbjct: 123 VRRQGRGT-------FVTISSGCGLMGVPGLGAYCASK 153
>UniRef50_A5ICI0 Cluster: Oxidoreductase, short chain
dehydrogenase/reductase family; n=4; Legionella
pneumophila|Rep: Oxidoreductase, short chain
dehydrogenase/reductase family - Legionella pneumophila
(strain Corby)
Length = 283
Score = 57.2 bits (132), Expect = 3e-07
Identities = 43/163 (26%), Positives = 74/163 (45%)
Frame = +1
Query: 121 SRLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVE 300
++++ +TGC SG+G+ L G IA K TE + L LDV+
Sbjct: 5 TKVILITGCSSGIGFDAVFALKNRGHRVIASCRK---TEDVQKLLNKGVEALLLDVSNPI 61
Query: 301 SVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVIS 480
S+Q +L + + ++NNAG VG E ++ ++ N+ G + +
Sbjct: 62 SIQSAFAQLLIMTSGH----LDVLINNAGYGQVGALEDISRDILRQQFETNVFGLQDLTN 117
Query: 481 AFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
+P +R+ + + RIIN+ S G+ +P AY+ASK
Sbjct: 118 LVIPVMRE-------QGQGRIINISSILGVVSMPFRGAYNASK 153
>UniRef50_A3YG01 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Marinomonas sp. MED121|Rep: Short-chain
dehydrogenase/reductase SDR - Marinomonas sp. MED121
Length = 265
Score = 57.2 bits (132), Expect = 3e-07
Identities = 48/170 (28%), Positives = 75/170 (44%), Gaps = 5/170 (2%)
Frame = +1
Query: 118 VSRLVAVTGCDSGLGWAVAARLAREGFITIAGMH---KGIETEAAKALEKLCAHT--FPL 282
+ + + +TGC SG G+ A +G+ IA M +GI EA K L
Sbjct: 9 IMKTILITGCSSGFGYESAYHFLDKGWHVIATMRNLDEGIFKEALKDKSGAQGRLELLEL 68
Query: 283 DVTRVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLG 462
DVT S+ + V T+ A+VNNAG+ + +E + + N
Sbjct: 69 DVTDATSIANLVESVGTI---------DALVNNAGIGWLSPFEGTSDENVRRIFETNTFA 119
Query: 463 AMRVISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKS 612
+I A LP++R+ + I+NV S ++PLP A Y+ASK+
Sbjct: 120 VFEMIRALLPKMRQQG-------EGVIVNVSSSVTMKPLPLLAVYTASKA 162
>UniRef50_A1UD76 Cluster: Short-chain dehydrogenase/reductase SDR;
n=12; Bacteria|Rep: Short-chain dehydrogenase/reductase
SDR - Mycobacterium sp. (strain KMS)
Length = 246
Score = 57.2 bits (132), Expect = 3e-07
Identities = 47/169 (27%), Positives = 78/169 (46%), Gaps = 3/169 (1%)
Frame = +1
Query: 115 SVSRLVAVTGCDSGLGWAVAARLAREGFITIAGMHKG--IETEAAKALEK-LCAHTFPLD 285
++SR+VA+TG SG+G A A LAR G + G + ++ AA+ E A D
Sbjct: 4 TMSRVVAITGASSGIGEATARELARRGAAVVLGARRADHLDRVAAEIREAGGAAVVCTAD 63
Query: 286 VTRVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGA 465
VTR++ V+ + + +VNNAG+ +G + + + VNL G
Sbjct: 64 VTRLDDVRRLADRAVDEFG-----RLDVMVNNAGIGRIGPISDLDVDGWSAMIDVNLRGV 118
Query: 466 MRVISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKS 612
+ I+A LP R+ + + S GL+ +P Y+A+K+
Sbjct: 119 LHGIAAALPIFRR-------QGHGHFVTTVSTAGLKIVPDQGVYAATKN 160
>UniRef50_A0QZW1 Cluster: 3-oxoacyl-[acyl-carrier-protein]
reductase; n=1; Mycobacterium smegmatis str. MC2
155|Rep: 3-oxoacyl-[acyl-carrier-protein] reductase -
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Length = 236
Score = 57.2 bits (132), Expect = 3e-07
Identities = 54/168 (32%), Positives = 74/168 (44%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVES 303
++ +TG D GLG AVA RLA++GF + G H G +EA + E L T P DVT
Sbjct: 4 KVAVLTGADGGLGRAVAQRLAKDGFTLVLGYHPG--SEAPQTPEAL---TVPADVTSEHD 58
Query: 304 VQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISA 483
V + LT + A+V AGVM + + + VNL G A
Sbjct: 59 VAK-----LTSAAVIEYGRIDALVTLAGVMEQTLLPDLDLATWNQTIAVNLTGTFLCAKA 113
Query: 484 FLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKSWPFGV 627
E+ KT I+ +GS G AAY+ASK+ G+
Sbjct: 114 AADELMKTG--------GTIVTIGSQIGYVGGINCAAYTASKAGVAGL 153
>UniRef50_Q1ITJ9 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Acidobacteria bacterium Ellin345|Rep: Short-chain
dehydrogenase/reductase SDR - Acidobacteria bacterium
(strain Ellin345)
Length = 281
Score = 56.8 bits (131), Expect = 4e-07
Identities = 51/165 (30%), Positives = 71/165 (43%), Gaps = 3/165 (1%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREGFITIAGMHK--GIETEAAKAL-EKLCAHTFPLDVTR 294
R V VTG G+G+ +A A G+ A M G A KA E L +DV R
Sbjct: 2 RSVLVTGSSKGIGYEIAIAFAHAGYRVFATMRNPSGSPALAEKAAAESLPIFVSAMDVDR 61
Query: 295 VESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRV 474
+SV + + K P ++NNAGV G E + + + N GA+R
Sbjct: 62 DDSVANAIAAIQS--KHGP---IDILINNAGVDRAGSIEEQSLDDFRACMETNYFGAIRC 116
Query: 475 ISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
I A +P++R+ T IIN+ S G P AY +SK
Sbjct: 117 IKAVVPQMRERRSGT-------IINISSVAGSFSHPPMTAYCSSK 154
>UniRef50_A6G575 Cluster: Oxidoreductase, short chain
dehydrogenase/reductase family protein; n=1;
Plesiocystis pacifica SIR-1|Rep: Oxidoreductase, short
chain dehydrogenase/reductase family protein -
Plesiocystis pacifica SIR-1
Length = 279
Score = 56.8 bits (131), Expect = 4e-07
Identities = 53/163 (32%), Positives = 70/163 (42%), Gaps = 3/163 (1%)
Frame = +1
Query: 130 VAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTF-PLDVTRVESV 306
+ VTG SG+G + A LA G + E AK + TF +DV SV
Sbjct: 4 ILVTGASSGIGLSTARLLASRGHRVFGTSRRSPEAVVAKLGAQ--PFTFVTMDVRDPGSV 61
Query: 307 QEFRKYVLTVLKDN--PKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVIS 480
V + D P VVNNAG+ G E + + + N LG RV
Sbjct: 62 AAAIAEVHRQIADELGPDQGLDVVVNNAGMGVAGALEDTSDAEALEQLDTNFLGVHRVCR 121
Query: 481 AFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
A LP++R ++ + RI+NVGS G LP YSASK
Sbjct: 122 AVLPDMR-------ARGRGRIVNVGSLAGRITLPFQGFYSASK 157
>UniRef50_A5FD88 Cluster: Short-chain dehydrogenase/reductase SDR;
n=2; Flavobacteriaceae|Rep: Short-chain
dehydrogenase/reductase SDR - Flavobacterium johnsoniae
UW101
Length = 246
Score = 56.8 bits (131), Expect = 4e-07
Identities = 54/181 (29%), Positives = 89/181 (49%), Gaps = 13/181 (7%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREG-FITIAGMHKGIETEAAKALEKLCAHTF------PL 282
+ V +TG + G+G+ A +L ++G F+ IA + G ALEKL A F L
Sbjct: 2 KTVLITGANKGIGFETARQLLQKGFFVFIASRNPG---NGLTALEKLKAEGFSNVESIEL 58
Query: 283 DVTRVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVG-KYEWMTASMIE--SPVHVN 453
DVT + S+Q R+ ++ + ++NNAG+ Y + AS ++ V+ N
Sbjct: 59 DVTDLCSIQTAREKIVEKVS-----VLDVLINNAGINGGSPPYTVLEASSVQYLDAVNTN 113
Query: 454 LLGAMRVISAFLPEIRKTAIETTSKPKPRIINVGSHCG---LQPLPAFAAYSASKSWPFG 624
L+G V F+ ++K++ +PRI+NV + G LQ P + AYS +K +
Sbjct: 114 LIGTANVTQIFIDLLKKSS-------EPRIVNVSTSVGSLALQSNPQWPAYSYAKYGVYA 166
Query: 625 V 627
V
Sbjct: 167 V 167
>UniRef50_P0AFP5 Cluster: Uncharacterized oxidoreductase ybbO; n=39;
Enterobacteriaceae|Rep: Uncharacterized oxidoreductase
ybbO - Escherichia coli O6
Length = 269
Score = 56.8 bits (131), Expect = 4e-07
Identities = 48/170 (28%), Positives = 73/170 (42%)
Frame = +1
Query: 100 IVSAMSVSRLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFP 279
I++ + + V +TGC SG+G A L R+GF +AG K + E + +
Sbjct: 8 ILTGKVMQKSVLITGCSSGIGLESALELKRQGFHVLAGCRKPDDVE---RMNSMGFTGVL 64
Query: 280 LDVTRVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLL 459
+D+ ESV V+ L DN Y + NNAG G ++ + +E N
Sbjct: 65 IDLDSPESVDRAADEVI-ALTDNCLY---GIFNNAGFGMYGPLSTISRAQMEQQFSANFF 120
Query: 460 GAMRVISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
GA ++ LP + + RI+ S GL P AY+ASK
Sbjct: 121 GAHQLTMRLLPAM-------LPHGEGRIVMTSSVMGLISTPGRGAYAASK 163
>UniRef50_P14061 Cluster: Estradiol 17-beta-dehydrogenase 1; n=38;
Euteleostomi|Rep: Estradiol 17-beta-dehydrogenase 1 -
Homo sapiens (Human)
Length = 328
Score = 56.8 bits (131), Expect = 4e-07
Identities = 53/170 (31%), Positives = 83/170 (48%), Gaps = 9/170 (5%)
Frame = +1
Query: 127 LVAVTGCDSGLGWAVAARLAREG------FITIAGMH-KGIETEAAKALE--KLCAHTFP 279
+V +TGC SG+G +A RLA + + T+ + +G EAA+AL T
Sbjct: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 64
Query: 280 LDVTRVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLL 459
LDV +SV R+ V D +V NAG+ +G E + + S + VN++
Sbjct: 65 LDVRDSKSVAAARERVTEGRVD-------VLVCNAGLGLLGPLEALGEDAVASVLDVNVV 117
Query: 460 GAMRVISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
G +R++ AFLP++++ + R++ GS GL LP Y ASK
Sbjct: 118 GTVRMLQAFLPDMKR-------RGSGRVLVTGSVGGLMGLPFNDVYCASK 160
>UniRef50_Q81RT0 Cluster: Oxidoreductase, short-chain
dehydrogenase/reductase family; n=19; Bacteria|Rep:
Oxidoreductase, short-chain dehydrogenase/reductase
family - Bacillus anthracis
Length = 242
Score = 56.4 bits (130), Expect = 5e-07
Identities = 53/164 (32%), Positives = 74/164 (45%)
Frame = +1
Query: 136 VTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESVQEF 315
+TG G+G AVA LA+EG + + + + E A A E + T S E
Sbjct: 15 ITGAGRGIGRAVAIALAKEG-VNVGLLARSEENLKAVAKEVEAEGVKAVIATADVSSYEE 73
Query: 316 RKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAFLPE 495
+ LK N ++NNAG+ GK+ + + E + VNL+G A LP
Sbjct: 74 VTTAIETLK-NGLGSIDILINNAGISKFGKFLELDVADWEKIIQVNLMGVYYATRAALPS 132
Query: 496 IRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKSWPFGV 627
+ IE S IIN+ S G + P +AYSASK FGV
Sbjct: 133 M----IEQQSGD---IINISSTAGQKGAPVTSAYSASK---FGV 166
>UniRef50_Q5KRX7 Cluster: Putative oxidoreductase; n=2;
Corynebacterium glutamicum|Rep: Putative oxidoreductase
- Corynebacterium glutamicum (Brevibacterium flavum)
Length = 279
Score = 56.4 bits (130), Expect = 5e-07
Identities = 46/164 (28%), Positives = 79/164 (48%), Gaps = 2/164 (1%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREGF-ITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVE 300
++ +TG SG+G + A LA G + I ++ + E K + + AH L+VT
Sbjct: 38 KVAFITGAASGMGASHARVLAAHGAKVVITDLNDELGQELVKEIGEEKAHYVHLNVT--- 94
Query: 301 SVQEFRKYVLTVLKDNPKY-KFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVI 477
F ++ + V K ++ K ++NNAG+ + G E TA+ + + ++L G +
Sbjct: 95 ---SFEEWEVAVQKALERFGKIDTLINNAGIFSSGSVEDATAADWDKTIAIDLNGTFYGM 151
Query: 478 SAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
A LP +++ P IIN+ S G+ AAYSA+K
Sbjct: 152 KAALPALKE-------NPTASIINISSIAGVTGFKNRAAYSAAK 188
>UniRef50_A6EJ72 Cluster: Short-chain dehydrogenase; n=1; Pedobacter
sp. BAL39|Rep: Short-chain dehydrogenase - Pedobacter
sp. BAL39
Length = 269
Score = 56.4 bits (130), Expect = 5e-07
Identities = 45/164 (27%), Positives = 72/164 (43%)
Frame = +1
Query: 118 VSRLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRV 297
+++ + +TG +G+G A A +G+ IA M AA+ E LDVT+
Sbjct: 1 MAKTIFITGASTGIGKTTALYFAAKGWQVIATMRN--TQSAAELAENKNITLLTLDVTKP 58
Query: 298 ESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVI 477
E + + V + + V+NNAG TVG E + I + N LG +++
Sbjct: 59 EQIAD------AVKQATEMGQVDVVLNNAGYGTVGPLEGTSDEDIRQIIDTNFLGVIQLT 112
Query: 478 SAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
AF+P R+ + I + S GL P F+ Y A+K
Sbjct: 113 KAFIPHFRE-------RQSGVFITISSIGGLVAYPFFSLYHATK 149
>UniRef50_Q5BII6 Cluster: RH05486p; n=4; Sophophora|Rep: RH05486p -
Drosophila melanogaster (Fruit fly)
Length = 255
Score = 56.4 bits (130), Expect = 5e-07
Identities = 49/170 (28%), Positives = 83/170 (48%), Gaps = 3/170 (1%)
Frame = +1
Query: 112 MSVS-RLVAVTGCDSGLGWAVAARLAREG-FITIAGMHKGIETEAAKALEKLCAHTFPLD 285
MS+S ++V VTG SG+G A+A LAREG + + G + K+L+ A D
Sbjct: 5 MSLSNKVVIVTGASSGIGAAIAQVLAREGATLALVGRNVANLEATKKSLKGTQAEIVVAD 64
Query: 286 VTR-VESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLG 462
VT+ +++ + T+ K + +VNNAG++ G + ++ ++ NL G
Sbjct: 65 VTKDADAIVQ-----QTLAKFG---RIDVLVNNAGILGKGGLIDLDIEEFDAVLNTNLRG 116
Query: 463 AMRVISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKS 612
+ + A LP + KT K ++NV S G++P +Y SK+
Sbjct: 117 VILLTKAVLPHLLKT--------KGAVVNVSSCAGIRPFAGALSYGVSKA 158
>UniRef50_Q09851 Cluster: Uncharacterized oxidoreductase C23D3.11;
n=1; Schizosaccharomyces pombe|Rep: Uncharacterized
oxidoreductase C23D3.11 - Schizosaccharomyces pombe
(Fission yeast)
Length = 296
Score = 56.4 bits (130), Expect = 5e-07
Identities = 48/168 (28%), Positives = 74/168 (44%), Gaps = 1/168 (0%)
Frame = +1
Query: 112 MSVSRLVAVTGC-DSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDV 288
M + V +TGC + G+G A+A + +EGF +A + E L K T LDV
Sbjct: 1 MEAEKFVLITGCSEGGIGNALALKFHQEGFQVLATAR---QVERMDNLTKAGLQTLKLDV 57
Query: 289 TRVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAM 468
T +SV+E + V + H ++NNAG + + + VN G +
Sbjct: 58 TDEDSVREVEQEVRKFTNGS----LHYLINNAGAPCSAPAIDLDIEDVSKVMDVNFYGVI 113
Query: 469 RVISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKS 612
R+ AF ++ + K I+NV S P AAY+ASK+
Sbjct: 114 RMNKAFQHQLIRA--------KGTIVNVNSLVSYVPFAFNAAYNASKA 153
>UniRef50_Q7UIV9 Cluster: Ketoacyl reductase; n=1; Pirellula
sp.|Rep: Ketoacyl reductase - Rhodopirellula baltica
Length = 339
Score = 56.0 bits (129), Expect = 7e-07
Identities = 51/166 (30%), Positives = 73/166 (43%), Gaps = 3/166 (1%)
Frame = +1
Query: 121 SRLVAVTGCDSGLGWAVAARLAREGF-ITIAGMHKGIETEAAKALEKLCAHTF--PLDVT 291
++ V +TG GLG +A +LA +G I I + AA L + A P DV
Sbjct: 35 NKRVVITGGSRGLGLVIARQLADQGARIAITARTEEDLCAAAAELRRRGAEVIAHPCDVR 94
Query: 292 RVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMR 471
E V F V N ++N AG++TVG +E MT +S + N GA+
Sbjct: 95 DREQVATFIDRVT-----NQFDGIDVLLNVAGIITVGPFESMTMEDFQSAMQTNCWGALH 149
Query: 472 VISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
V LP +R RI+N+ S G + +P Y+ASK
Sbjct: 150 VAMEVLPHMRAAG-------WGRIVNIASLGGKRAVPHMLPYAASK 188
>UniRef50_Q41CM8 Cluster: Short-chain dehydrogenase/reductase SDR
precursor; n=1; Exiguobacterium sibiricum 255-15|Rep:
Short-chain dehydrogenase/reductase SDR precursor -
Exiguobacterium sibiricum 255-15
Length = 270
Score = 56.0 bits (129), Expect = 7e-07
Identities = 46/165 (27%), Positives = 81/165 (49%), Gaps = 5/165 (3%)
Frame = +1
Query: 136 VTGCDSGLGWAVAARLAREGF--ITIAGMHKGIETEAAKALEK---LCAHTFPLDVTRVE 300
+TG G+G +A AR+GF + IA K + TE LEK + A+TF D+++ +
Sbjct: 8 ITGASGGIGLDLAVLAARDGFDCVLIARNEKKL-TELKHVLEKRYQIKAYTFAADLSKPD 66
Query: 301 SVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVIS 480
SV +L+ L+++ + + NNAG T G++ + S + +HVN++ +
Sbjct: 67 SVSR----ILSFLEEH-ELTVDLLFNNAGFATSGRFAEIDPSEDLNSIHVNVVALTELTK 121
Query: 481 AFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKSW 615
+P + + RI+NV S P P + Y A+K++
Sbjct: 122 RLVPGM-------LDRGFGRILNVASVAAFMPGPYMSVYYATKAY 159
>UniRef50_Q1JYA3 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Desulfuromonas acetoxidans DSM 684|Rep: Short-chain
dehydrogenase/reductase SDR - Desulfuromonas acetoxidans
DSM 684
Length = 283
Score = 56.0 bits (129), Expect = 7e-07
Identities = 49/169 (28%), Positives = 78/169 (46%)
Frame = +1
Query: 103 VSAMSVSRLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPL 282
+++M R V VTG SG+G +A L + + IA + + E L +L T L
Sbjct: 1 MTSMGQQRWVVVTGASSGIGRDIALTLYQYDYRVIATARRDEDLEE---LRRLGLTTCAL 57
Query: 283 DVTRVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLG 462
++ SV +L+ L DN Y A++NNA G E ++ +E VNL G
Sbjct: 58 ELADSASVDRAINTILS-LCDNALY---ALINNAAYGQPGAVEDLSRDSLEQQFAVNLFG 113
Query: 463 AMRVISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
++ LP +++ A + R++ + S GL P AY+ASK
Sbjct: 114 THQLTVGLLPALKQGA-------EGRLVTISSVLGLVAFPWQGAYNASK 155
>UniRef50_A5FF05 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Flavobacterium johnsoniae UW101|Rep: Short-chain
dehydrogenase/reductase SDR - Flavobacterium johnsoniae
UW101
Length = 285
Score = 56.0 bits (129), Expect = 7e-07
Identities = 49/168 (29%), Positives = 71/168 (42%), Gaps = 4/168 (2%)
Frame = +1
Query: 118 VSRLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTF---PLDV 288
+S+ + +TG +G G A LA G IAGM + AA A E +DV
Sbjct: 1 MSKTIFITGTSTGFGKLTALTLANAGHSVIAGMRNTNDKNAAAAKELGAVENIEVVDIDV 60
Query: 289 TRVESVQEFRKYVLTVLKDNPKY-KFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGA 465
T SV + + V+T KY K ++NNA V G E + + VN+
Sbjct: 61 TDDASVNKAIEKVIT------KYGKIDVLINNAAVSGFGLLEGYSIDQVRKMFDVNVYSV 114
Query: 466 MRVISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
+R+ A LP +RK + +IN+ + LP Y ASK
Sbjct: 115 LRMYQAVLPSMRK-------ERNGLVINITTGASGHTLPFMVPYIASK 155
>UniRef50_A5CSQ5 Cluster: Short chain dehydrogenase/oxidoreductase;
n=6; Bacteria|Rep: Short chain
dehydrogenase/oxidoreductase - Clavibacter michiganensis
subsp. michiganensis (strain NCPPB 382)
Length = 265
Score = 56.0 bits (129), Expect = 7e-07
Identities = 47/162 (29%), Positives = 74/162 (45%), Gaps = 3/162 (1%)
Frame = +1
Query: 136 VTGCDSGLGWAVAARLAREG-FITIAGMHKGIETEAAKALE-KLCAHTFPLDVTRVESVQ 309
+TG DSG+GW A L EG + ++ +G EAA L+ H F DVT VES+
Sbjct: 12 ITGADSGIGWETARILLSEGATVVLSDQDQGSLDEAAAKLDGGDRVHAFAADVTSVESLA 71
Query: 310 EFRKYVLTVLKDNPKYKFHAVVNNAGVM-TVGKYEWMTASMIESPVHVNLLGAMRVISAF 486
V + D +V +AG+ G + + + + V+L+G +R++ F
Sbjct: 72 ALHDKVQEAVGD-----IDILVQSAGITGAQGLFHEIDDEGWTNTIEVDLMGPVRLVKRF 126
Query: 487 LPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKS 612
LP +RK RI+ + S +QP Y A+K+
Sbjct: 127 LPSLRKGG-------WGRIVFLASEDAVQPYDDELPYCAAKA 161
>UniRef50_Q2U1R9 Cluster: Dehydrogenases with different
specificities; n=4; Pezizomycotina|Rep: Dehydrogenases
with different specificities - Aspergillus oryzae
Length = 286
Score = 56.0 bits (129), Expect = 7e-07
Identities = 46/160 (28%), Positives = 70/160 (43%), Gaps = 2/160 (1%)
Frame = +1
Query: 136 VTGCDSGLGWAVAARLAREGFITIAGMHKGIET-EAAKALEKLCAHTFPLDVTRVESVQE 312
+TG SGLG +++ G I + ++ +A + ++ LDVT+ +++ E
Sbjct: 8 ITGASSGLGLSLSLYALSAGHHVIGTVRNASKSADAVQTIQNKGGKIVELDVTKADAIPE 67
Query: 313 FRKYVLTVLKDNPKY-KFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAFL 489
V K Y K +VNNAG +G E + + N G +RVI A L
Sbjct: 68 ------AVKKAESFYGKIDVLVNNAGYSLLGAVEDLNDKESALQMETNFFGPLRVIRAVL 121
Query: 490 PEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
P +R T I+N+ S G LP+ YSASK
Sbjct: 122 PGMRGNRSGT-------IVNISSVAGQDALPSCGLYSASK 154
>UniRef50_Q89FM8 Cluster: Dehydrogenase; n=1; Bradyrhizobium
japonicum|Rep: Dehydrogenase - Bradyrhizobium japonicum
Length = 255
Score = 55.6 bits (128), Expect = 1e-06
Identities = 53/180 (29%), Positives = 82/180 (45%), Gaps = 8/180 (4%)
Frame = +1
Query: 109 AMSVSRLVAVTGCDSGLGWAVAARLAREGF-ITIAGMHKGIETEAAKALEKL--CAHTFP 279
A+ + + VTG SG+G A+AA AREG + + ++ E A+ + K A +F
Sbjct: 2 ALLANHIAVVTGAGSGIGRAIAAGYAREGAQVVLLDVNADTVAEGAQEIRKAGGRAESFA 61
Query: 280 LDVTRVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIE---SPVHV 450
LDVTR + K V + + +VNNAG+ + T ++ + + +
Sbjct: 62 LDVTRRDDCFALAKQVADKVG-----QVSILVNNAGITRRNAFTAETETVAKDWNDIISL 116
Query: 451 NLLGAMRVISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPL--PAFAAYSASKSWPFG 624
NL G + AFL +R K RI+N+GS L P+ AAY+ SK G
Sbjct: 117 NLNGVFNMTQAFLAPLRAA--------KGRIVNIGSIQSFVHLRTPSSAAYTTSKHGVLG 168
>UniRef50_Q1CWB6 Cluster: Oxidoreductase, short chain
dehydrogenase/reductase family; n=1; Myxococcus xanthus
DK 1622|Rep: Oxidoreductase, short chain
dehydrogenase/reductase family - Myxococcus xanthus
(strain DK 1622)
Length = 334
Score = 55.6 bits (128), Expect = 1e-06
Identities = 48/166 (28%), Positives = 71/166 (42%), Gaps = 3/166 (1%)
Frame = +1
Query: 121 SRLVAVTGCDSGLGWAVAARLAREG-FITIAGMHKGIETEAAKALEKL--CAHTFPLDVT 291
+++V VTG SG+G A A LA +G + +A + + A+ L AH P DV+
Sbjct: 7 NQVVVVTGASSGIGRATALALANKGAHVVLAARREEPLEDLARECRGLGVQAHVVPTDVS 66
Query: 292 RVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMR 471
V +VQ V F A +NNAGV +G+ E + N G +
Sbjct: 67 DVAAVQHLADEARNVFG-----HFDAWINNAGVYLMGRLEETPDDAFRQVMETNFFGTVS 121
Query: 472 VISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
A + + R+ T ++NV S G P +AY ASK
Sbjct: 122 GARAAVAQFRRQGYGT-------LVNVSSTFGAVAAPYVSAYVASK 160
>UniRef50_Q11QG7 Cluster: Short-chain alcohol-related dehydrogenase;
n=1; Cytophaga hutchinsonii ATCC 33406|Rep: Short-chain
alcohol-related dehydrogenase - Cytophaga hutchinsonii
(strain ATCC 33406 / NCIMB 9469)
Length = 272
Score = 55.6 bits (128), Expect = 1e-06
Identities = 48/165 (29%), Positives = 78/165 (47%)
Frame = +1
Query: 118 VSRLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRV 297
++++V VTG SG+G ++ L +G+I + G + A + KL A LDV
Sbjct: 1 MNQVVLVTGGSSGIGKSICLYLHEKGYI-VYGTSRNPARYAHEVPFKLIA----LDVLDD 55
Query: 298 ESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVI 477
++ K ++ + + K +VNNAG+ +G E TA ++ N+ G +R
Sbjct: 56 TTITPALKTII-----DAEGKLDVLVNNAGIGMLGSIEDSTAEEVKEVFETNVYGILRTC 110
Query: 478 SAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKS 612
A LP +R+ + IINV S G LP YSA+K+
Sbjct: 111 QAVLPHMRE-------RKMGLIINVSSIAGYMGLPYRGIYSATKA 148
>UniRef50_Q0S3V2 Cluster: Short chain dehydrogenase; n=4;
Bacteria|Rep: Short chain dehydrogenase - Rhodococcus
sp. (strain RHA1)
Length = 276
Score = 55.6 bits (128), Expect = 1e-06
Identities = 50/165 (30%), Positives = 77/165 (46%), Gaps = 3/165 (1%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREGF-ITIAGMHKGIETEAAKALEKLCAHTFP--LDVTR 294
++V +TG SG+G A+A LA G + I+ M E A+ E L A LDVT+
Sbjct: 7 KVVVITGAGSGIGRALALNLAGRGARLAISDMDTVGLAETARQAEALGAEVKADHLDVTQ 66
Query: 295 VESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRV 474
E+V + V K + V NNAG+ G++E IE + V+ G +
Sbjct: 67 REAVLAYADDVRAHFG-----KINQVYNNAGIAYHGEFEKSEFKDIERIMDVDFWGVVNG 121
Query: 475 ISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
AFLP + + ++NV S GL +P +AY+++K
Sbjct: 122 TKAFLPHL-------IASGDGHVVNVSSLFGLLSMPGQSAYNSAK 159
>UniRef50_A5ELU7 Cluster: Putative Short-chain
dehydrogenase/reductase SDR; n=1; Bradyrhizobium sp.
BTAi1|Rep: Putative Short-chain dehydrogenase/reductase
SDR - Bradyrhizobium sp. (strain BTAi1 / ATCC BAA-1182)
Length = 267
Score = 55.6 bits (128), Expect = 1e-06
Identities = 45/166 (27%), Positives = 79/166 (47%), Gaps = 2/166 (1%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREGF--ITIAGMHKGIETEAAKALEKLCAHTFPLDVTRV 297
R VTG SG+G A A RLA G+ I +A + +E E A+ + T + +
Sbjct: 6 RFAVVTGASSGIGVAYAERLAARGYYLILVARRRERLE-ETARNIRAKTNVTVEIVTADL 64
Query: 298 ESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVI 477
+ + V T+++ + +VNNAG+ +G ++A+ +++ + +N+ R+
Sbjct: 65 GDSNDLSR-VATLIEG--REDIDLLVNNAGLGALGLTAQVSAAALDNLIKINVQALTRLT 121
Query: 478 SAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKSW 615
A LP + + + IIN+ S L P P A YS SK++
Sbjct: 122 HAALPGFLR-------RDRGTIINIASIIALMPTPTGAGYSGSKAY 160
>UniRef50_A3R4Q6 Cluster: Oxidoreductase; n=1; Streptomyces
vitaminophilus|Rep: Oxidoreductase - Streptomyces
vitaminophilus
Length = 313
Score = 55.6 bits (128), Expect = 1e-06
Identities = 43/160 (26%), Positives = 67/160 (41%)
Frame = +1
Query: 130 VAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESVQ 309
V +TG +G+G A A LA GF AG+ K + + + K LDVT E ++
Sbjct: 11 VVITGASTGIGRACALHLAENGFQVFAGVRKEADGASLERDAKGSLRALLLDVTDQEQIE 70
Query: 310 EFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAFL 489
+ + K +VNNAG+ E + ++ VN+ G + V FL
Sbjct: 71 A----AAAEVSRSSGGKLRCLVNNAGIGIPAPTELVDLDLLRRQFEVNVFGQVAVTQEFL 126
Query: 490 PEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
P +R RI+N+GS +P ++SK
Sbjct: 127 PLLRAAT--------GRIVNMGSIADRLTMPFAGPLNSSK 158
>UniRef50_A3PV65 Cluster: Short-chain dehydrogenase/reductase SDR
precursor; n=30; cellular organisms|Rep: Short-chain
dehydrogenase/reductase SDR precursor - Mycobacterium
sp. (strain JLS)
Length = 283
Score = 55.6 bits (128), Expect = 1e-06
Identities = 48/162 (29%), Positives = 69/162 (42%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVES 303
R + +TG SGLG A AA G + + K + EA +AL AH LDVT E+
Sbjct: 2 RTILITGVSSGLGRAFAAGALDAGHRVVGTVRKAEDAEAFEALSPGRAHARLLDVTDDEA 61
Query: 304 VQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISA 483
V R P V+ NAG G +E + + + N+ G + A
Sbjct: 62 V--LRTVADVEATVGP---IDVVIANAGYGVEGVFEETPLAELRAQFATNVFGVAATLQA 116
Query: 484 FLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
LP +R+ + ++ V S GL +P +AY ASK
Sbjct: 117 ALPAMRE-------RRSGHLMAVTSMAGLMAVPGMSAYCASK 151
>UniRef50_A0GPK9 Cluster: Short-chain dehydrogenase/reductase SDR
precursor; n=3; Burkholderia|Rep: Short-chain
dehydrogenase/reductase SDR precursor - Burkholderia
phytofirmans PsJN
Length = 266
Score = 55.6 bits (128), Expect = 1e-06
Identities = 50/172 (29%), Positives = 80/172 (46%), Gaps = 7/172 (4%)
Frame = +1
Query: 115 SVSRLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLC----AHTFPL 282
S S + VTG SG+G A A R A+ G+ G + A ++E C A T
Sbjct: 4 SSSPVCVVTGSASGIGAATALRFAQAGWSVAIGNFDDSTRQTALSVEAACRDAGASTLIF 63
Query: 283 DVTRVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTV---GKYEWMTASMIESPVHVN 453
D V + R+ + TV + + A++N AG V ++ + A E VN
Sbjct: 64 DAD-VGNDAHCRRAMDTVA--SRWQRVDALINCAGTTRVIAHNAFDEIDAVEFERVYRVN 120
Query: 454 LLGAMRVISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
L+G ++ A +P +R++A +T K ++N+ S GL + AY+ASK
Sbjct: 121 LIGLYQMTRAAVPLLRESAGLSTVKRSTSVVNISSLAGLNGTGSSIAYAASK 172
>UniRef50_Q38D51 Cluster: Short-chain dehydrogenase, putative; n=3;
Trypanosoma|Rep: Short-chain dehydrogenase, putative -
Trypanosoma brucei
Length = 426
Score = 55.6 bits (128), Expect = 1e-06
Identities = 47/154 (30%), Positives = 79/154 (51%), Gaps = 6/154 (3%)
Frame = +1
Query: 121 SRLVAVTGCDSGLGWAVAARLAREGF-ITIAGMHKGIETEAAKAL----EKLCAHTF-PL 282
SR+ VTG SG+G+AV +L G+ + +AG + EA K + CA L
Sbjct: 71 SRVALVTGASSGIGFAVTQQLVEHGWRVVMAGRSEERLLEARKKIMVRNPAGCAIVVGVL 130
Query: 283 DVTRVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLG 462
D++ + SV++F + V+T KD + +VN AGV+ + + +E + N++G
Sbjct: 131 DLSDLSSVRDFAE-VVTGQKD--QLSLSLLVNAAGVLR-RRLHRCDGTGMEEMIATNVVG 186
Query: 463 AMRVISAFLPEIRKTAIETTSKPKPRIINVGSHC 564
M + LP + +TA+ T + RI+N+ S C
Sbjct: 187 PMLLTELLLPLLDETALRTGA--SSRIVNIASSC 218
>UniRef50_Q7NIM9 Cluster: Gll2154 protein; n=2; Bacteria|Rep:
Gll2154 protein - Gloeobacter violaceus
Length = 246
Score = 55.2 bits (127), Expect = 1e-06
Identities = 51/167 (30%), Positives = 72/167 (43%), Gaps = 1/167 (0%)
Frame = +1
Query: 112 MSVSRLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVT 291
M V R+ VTG +G+G A A LA EGF G + +E A A E C LDVT
Sbjct: 1 MGVKRVAVVTGASAGIGAATARVLAGEGFSVYGGARR-VERLEALAREAGCI-PLALDVT 58
Query: 292 RVESVQEFRKYVLTVLKDNPKYKFHAVVNNA-GVMTVGKYEWMTASMIESPVHVNLLGAM 468
SV F + L D + H +VNNA G + + + M + N+LG +
Sbjct: 59 DPASVDAFAAH----LPD----RVHVLVNNAGGALGLDRIVEMDEQRWLAMYQTNVLGLV 110
Query: 469 RVISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
RV A + + ++N+GS GL+ Y+A K
Sbjct: 111 RVSKALFGRLEASG-------SAHVVNIGSIAGLETYVGGGGYTAVK 150
>UniRef50_Q1N3U9 Cluster: Short chain dehydrogenase; n=1;
Oceanobacter sp. RED65|Rep: Short chain dehydrogenase -
Oceanobacter sp. RED65
Length = 278
Score = 55.2 bits (127), Expect = 1e-06
Identities = 45/164 (27%), Positives = 75/164 (45%), Gaps = 3/164 (1%)
Frame = +1
Query: 130 VAVTGCDSGLGWAVAARLAREGF-ITIAGMH-KGI-ETEAAKALEKLCAHTFPLDVTRVE 300
V +TG G G A+A A G+ I ++ + +G+ ET L AH D+T+ E
Sbjct: 10 VLITGAAKGFGRALALSFAHRGWRILLSDIDTEGLAETAELVDLAGGMAHWVQCDITQPE 69
Query: 301 SVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVIS 480
V + + + ++NNAG+ G++ + S + NL+G +R
Sbjct: 70 QVTRMYDTAMELWQG-----VDVLINNAGIYAGGRFADIPESNWSKVLDTNLIGTIRCCQ 124
Query: 481 AFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKS 612
F+P +K + RI+N+ S G+ P+P A YS SK+
Sbjct: 125 KFVPMFQK-------QRSGRIVNIASLSGILPMPGSAFYSISKA 161
>UniRef50_Q0LEN5 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Herpetosiphon aurantiacus ATCC 23779|Rep:
Short-chain dehydrogenase/reductase SDR - Herpetosiphon
aurantiacus ATCC 23779
Length = 297
Score = 55.2 bits (127), Expect = 1e-06
Identities = 45/171 (26%), Positives = 77/171 (45%), Gaps = 4/171 (2%)
Frame = +1
Query: 112 MSVSRLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKL----CAHTFP 279
M+ ++ + VTG SGLG A+ LA+ G A M +GI + A+A ++L H
Sbjct: 1 MAHAQTILVTGSSSGLGRAIVETLAQHGHTVFASM-RGIAGKNAQAAQELRDFASQHGLN 59
Query: 280 LDVTRVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLL 459
++ ++ V + + ++NNAG G E + ++ +N+
Sbjct: 60 IEPIELDVVNQASVDQAIATIQAKAGRLDCLINNAGAGLAGLTEACSIEQVQQLFDINVF 119
Query: 460 GAMRVISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKS 612
GA+RV A LP +R+ + +I + S +P AAY ASK+
Sbjct: 120 GALRVSKAVLPLMRQ-------QQAGLLITISSTSTQIVVPFLAAYGASKA 163
>UniRef50_A5L8A4 Cluster: Short-chain dehydrogenase/reductase SDR;
n=3; Proteobacteria|Rep: Short-chain
dehydrogenase/reductase SDR - Vibrionales bacterium
SWAT-3
Length = 287
Score = 55.2 bits (127), Expect = 1e-06
Identities = 46/165 (27%), Positives = 74/165 (44%), Gaps = 3/165 (1%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREGFI---TIAGMHKGIETEAAKALEKLCAHTFPLDVTR 294
++V +TG +SG+G A A++ + ++ + KG+E E A + L DVTR
Sbjct: 11 QVVLITGANSGMGLETALLFAQKNYRVYGSVRSIAKGLELEKVFAEKGLSITPVVCDVTR 70
Query: 295 VESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRV 474
+ V + + V+ + + +VNNAG V E T VN+ G +R
Sbjct: 71 TQDVNDAIRMVM-----SDAGRLDILVNNAGYGLVASVEEGTDEEFMHQFDVNVFGVLRT 125
Query: 475 ISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
A +P +R+ + IINV S G LP Y++SK
Sbjct: 126 CRAVIPFMRE-------QNSGMIINVSSFLGKMGLPLLTHYNSSK 163
>UniRef50_A4ABL9 Cluster: Short-chain dehydrogenase/reductase SDR;
n=3; Proteobacteria|Rep: Short-chain
dehydrogenase/reductase SDR - Congregibacter litoralis
KT71
Length = 686
Score = 55.2 bits (127), Expect = 1e-06
Identities = 53/168 (31%), Positives = 81/168 (48%), Gaps = 5/168 (2%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREG---FITIAGMHKGIETEAAKALEKLCAHTFPLDVTR 294
++V VTG SG+G A RLAR G + + K ET A + A + DV+
Sbjct: 394 QVVMVTGATSGIGKECALRLARAGATVLLVARTVEKLDETLQEIAQKGGDAQAYSCDVS- 452
Query: 295 VESVQEFRKYVLTVLKDNPKYKFHAVVNNAG--VMTVGKYEWMTASMIESPVHVNLLGAM 468
S ++ +K V VL+D+ +VNNAG + ++ + E + +N GA+
Sbjct: 453 --SEKDCQKLVRDVLRDHG--HVDVLVNNAGRSIRRSVRHSYDRFHDFERTMELNYFGAL 508
Query: 469 RVISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKS 612
R+I FLP + + + + IIN+ S L P F+AY ASKS
Sbjct: 509 RLILGFLPSMEE-------RERGHIINISSIGVLTNPPRFSAYVASKS 549
>UniRef50_A0Y8P7 Cluster: Short chain dehydrogenase; n=1; marine
gamma proteobacterium HTCC2143|Rep: Short chain
dehydrogenase - marine gamma proteobacterium HTCC2143
Length = 288
Score = 55.2 bits (127), Expect = 1e-06
Identities = 46/164 (28%), Positives = 67/164 (40%), Gaps = 3/164 (1%)
Frame = +1
Query: 127 LVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEA---AKALEKLCAHTFPLDVTRV 297
+ VTG +G+G+ + LAR G+ AGM + + A A E L +DVT
Sbjct: 3 IAVVTGTSTGIGFETSLHLARNGYYVFAGMRNTKKAQPLIDAAAAESLAVEVIEMDVTDG 62
Query: 298 ESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVI 477
S+ + N K + +VNNAG+ E N G + I
Sbjct: 63 SSLNGAFDII------NAKGQVSLLVNNAGIGGASPLELTPEDEHRQIFETNYFGTIACI 116
Query: 478 SAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
LP +R+ + K I+N+ S G+ P AYSASK
Sbjct: 117 QKVLPAMRE-------QGKGDIVNISSIVGILATPNQLAYSASK 153
>UniRef50_A5AAH5 Cluster: Catalytic activity: estradiol-17-beta +
NAD(+) = estrone + NADH. precursor; n=5;
Trichocomaceae|Rep: Catalytic activity:
estradiol-17-beta + NAD(+) = estrone + NADH. precursor -
Aspergillus niger
Length = 291
Score = 55.2 bits (127), Expect = 1e-06
Identities = 45/159 (28%), Positives = 67/159 (42%), Gaps = 1/159 (0%)
Frame = +1
Query: 136 VTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKA-LEKLCAHTFPLDVTRVESVQE 312
+TG SGLG ++A + G +A A + L LDV + +
Sbjct: 10 ITGSSSGLGASLAIAALKAGHKVLATARNPTTASAQNPQITSLGGIWISLDVNDPSTPNK 69
Query: 313 FRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAFLP 492
+ + T + VVNNAG +G E M+ S IES N+ G +RV+ LP
Sbjct: 70 IQSAINT----HADGIIDVVVNNAGYSLLGSIEDMSESEIESQFSTNVYGPIRVLKGVLP 125
Query: 493 EIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
+RK T ++N+ S G+ P A Y+ SK
Sbjct: 126 FMRKRRAGT-------VVNISSSAGVDGAPGCAVYAGSK 157
>UniRef50_UPI000058941E Cluster: PREDICTED: hypothetical protein;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 356
Score = 54.8 bits (126), Expect = 2e-06
Identities = 47/150 (31%), Positives = 72/150 (48%), Gaps = 5/150 (3%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREGFITIAGM-HKGIETEAAKALEKLCA----HTFPLDV 288
++ VTG SG+G A R+G I G H +A + ++K A PLD+
Sbjct: 41 KVAIVTGGASGIGLETAKAFCRKGIQVIIGSPHAENAKKAIQVIKKENALARVEWIPLDL 100
Query: 289 TRVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAM 468
+ ++SV++F + L N K H +VNNAGVM ++ TA E VN LG
Sbjct: 101 SSLQSVRDFAETFL-----NSKLPLHIIVNNAGVMMTPYHK--TADDFELQFQVNYLGHY 153
Query: 469 RVISAFLPEIRKTAIETTSKPKPRIINVGS 558
++ L ++ +A S+ +IINV S
Sbjct: 154 LLMRLLLDKLHNSA---HSRSYAKIINVSS 180
>UniRef50_Q9CC98 Cluster: Short chain alcohol dehydrogenase; n=36;
Bacteria|Rep: Short chain alcohol dehydrogenase -
Mycobacterium leprae
Length = 277
Score = 54.8 bits (126), Expect = 2e-06
Identities = 53/165 (32%), Positives = 79/165 (47%), Gaps = 3/165 (1%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREGF-ITIAGMH-KGI-ETEAAKALEKLCAHTFPLDVTR 294
++ VTG SG+G A+A LAR G + I+ + +G+ +TE A T LDVT
Sbjct: 7 KVAVVTGAGSGIGQALAIELARSGAKLAISDVDGEGLAQTEGQLKAIGASARTDRLDVTE 66
Query: 295 VESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRV 474
E+ F Y V+ +N K + + NNAG+ G E IE + V+ G +
Sbjct: 67 REA---FLTYA-DVVHEN-FGKVNQIYNNAGIAFTGDVEVSHFKDIERVMDVDYWGVVNG 121
Query: 475 ISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
AFLP + S +IN+ S GL +P AAY+++K
Sbjct: 122 TKAFLPYL-------ISSGDGHVINISSVFGLFSVPGQAAYNSAK 159
>UniRef50_O34782 Cluster: YvrD protein; n=3; Bacillus|Rep: YvrD
protein - Bacillus subtilis
Length = 263
Score = 54.8 bits (126), Expect = 2e-06
Identities = 45/167 (26%), Positives = 73/167 (43%), Gaps = 4/167 (2%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCA----HTFPLDVT 291
+LV +TG SG+G A A +EG I K + + +E+L H D++
Sbjct: 8 KLVLITGSTSGIGKAAAKSFLQEGAAVIVNGRK--QETVDRTIEELSGYGTVHGAAADLS 65
Query: 292 RVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMR 471
+ + F + K N +VNN G V + +T VN++ A+R
Sbjct: 66 KTDEAAAF------IEKVNEIGDIDILVNNLGFFEVKDFADVTDEEWNQYFEVNVMSAVR 119
Query: 472 VISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKS 612
FLP++ +K RI+N+ S G++PLP YS +K+
Sbjct: 120 TSRHFLPKM-------LAKNSGRILNIASEAGVKPLPTMIPYSMTKT 159
>UniRef50_A6UDX9 Cluster: Short-chain dehydrogenase/reductase SDR;
n=4; Alphaproteobacteria|Rep: Short-chain
dehydrogenase/reductase SDR - Sinorhizobium medicae
WSM419
Length = 251
Score = 54.8 bits (126), Expect = 2e-06
Identities = 51/171 (29%), Positives = 73/171 (42%), Gaps = 3/171 (1%)
Frame = +1
Query: 121 SRLVAVTGCDSGLGWAVAARLAREGF---ITIAGMHKGIETEAAKALEKLCAHTFPLDVT 291
+R VTG G+G A+A LA G+ I K + A +E+L +
Sbjct: 5 NRTALVTGASRGIGRAIAIGLAERGYDVAINDIERQKDVLAGVATEIEELGRRVITV-CA 63
Query: 292 RVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMR 471
V S E R V + AVVNNAG++ G E + +S + VN G
Sbjct: 64 DVSSKAEVRAMAKAV--GDAFGHLDAVVNNAGILISGDVEGLDEEHWDSVMDVNAKGTFL 121
Query: 472 VISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKSWPFG 624
V+ A LP ++ ++ RI+N+ S G P A YSASK+ G
Sbjct: 122 VVQAVLPMMK-------ARRYGRIVNIASIGGKHGAPEQAHYSASKAAVMG 165
>UniRef50_A6GAH4 Cluster: Oxidoreductase, short chain
dehydrogenase/reductase family protein; n=1;
Plesiocystis pacifica SIR-1|Rep: Oxidoreductase, short
chain dehydrogenase/reductase family protein -
Plesiocystis pacifica SIR-1
Length = 251
Score = 54.8 bits (126), Expect = 2e-06
Identities = 46/165 (27%), Positives = 78/165 (47%), Gaps = 1/165 (0%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREG-FITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVE 300
R +TG SG+G A+A LA EG + +A + E A+++ K AH +V
Sbjct: 4 RSALITGASSGIGAAIAHTLAAEGSSVVLAARREDKLAEVAESIAK--AHGADKVRVQVL 61
Query: 301 SVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVIS 480
V + + TV + + + F V+ NAGV ++ +E+ V VN+ GA+ ++
Sbjct: 62 DVSDPERTEATVRELDGELAFDLVIANAGVSKSTPGPKLSWKAVETVVSVNVCGAVATLT 121
Query: 481 AFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKSW 615
LP + + ++ V S + LP+ AAY ASK++
Sbjct: 122 GALPGM-------VERGAGHLVGVSSVAKYRGLPSSAAYCASKAF 159
>UniRef50_A6EHZ8 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Pedobacter sp. BAL39|Rep: Short-chain
dehydrogenase/reductase SDR - Pedobacter sp. BAL39
Length = 289
Score = 54.8 bits (126), Expect = 2e-06
Identities = 51/162 (31%), Positives = 71/162 (43%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVES 303
+ V VTG SG+G A A LA+ G+ + TE + L+ L +DVT ES
Sbjct: 22 KTVLVTGASSGIGKATAVYLAQNGYKVYGAARR---TEKLEELKTLGVIPISMDVTNEES 78
Query: 304 VQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISA 483
+ + V ++K+ +VNNAG G E M S + VN+ R+I
Sbjct: 79 LS---RCVERIMKE--AGGIDILVNNAGSGYYGALEDMPMSDARYQMEVNVFAVARLIQL 133
Query: 484 FLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
LP +RK +IIN+ S G LP Y ASK
Sbjct: 134 VLPGMRKNKY-------GKIINISSIGGKVTLPMGVWYHASK 168
>UniRef50_A3HWV9 Cluster: Short chain oxidoreductase; n=1;
Algoriphagus sp. PR1|Rep: Short chain oxidoreductase -
Algoriphagus sp. PR1
Length = 291
Score = 54.8 bits (126), Expect = 2e-06
Identities = 45/162 (27%), Positives = 67/162 (41%), Gaps = 2/162 (1%)
Frame = +1
Query: 130 VAVTGCDSGLGWAVAARLAREGFITIAGMH--KGIETEAAKALEKLCAHTFPLDVTRVES 303
+ VTG G +LA G + M +G A L+ +DVT ES
Sbjct: 5 ILVTGASGAFGSLACIQLAENGHQVVGTMRSLQGKNEPIANELKSKGVSLVKMDVTNEES 64
Query: 304 VQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISA 483
V K + ++ + NNAG+ G E T++ I+ +N+ G R++ A
Sbjct: 65 VNSGIKSAIELMDG-----LDTIFNNAGIGANGILECFTSNDIQKMFDINVFGVQRLMRA 119
Query: 484 FLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
LP +R+ K II+ S G P A+YSASK
Sbjct: 120 VLPHLRQQG-------KGTIIHTSSCIGRVTTPFLASYSASK 154
>UniRef50_A1UM02 Cluster: Short-chain dehydrogenase/reductase SDR
precursor; n=18; Corynebacterineae|Rep: Short-chain
dehydrogenase/reductase SDR precursor - Mycobacterium
sp. (strain KMS)
Length = 281
Score = 54.8 bits (126), Expect = 2e-06
Identities = 52/169 (30%), Positives = 76/169 (44%), Gaps = 6/169 (3%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREGFITIAGMHKG------IETEAAKALEKLCAHTFPLD 285
R V G SG+G A A LA GF G + ++T A+ E + H LD
Sbjct: 11 RPALVAGASSGIGAATAIELAAHGFPVALGARRVEKCQEIVDTIRAEGGEAIAVH---LD 67
Query: 286 VTRVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGA 465
VT +SV+ + + L D +V AG GK ++ ES + ++L+GA
Sbjct: 68 VTDPDSVKAAVEQTTSELGD-----IEVLVAGAGDTYFGKLADISTEQFESQIQIHLIGA 122
Query: 466 MRVISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKS 612
RV A LP + IE + + +I VGS L+ P AY A+K+
Sbjct: 123 NRVAGAVLPGM----IE---RQRGDLIFVGSDVALRQRPHMGAYGAAKA 164
>UniRef50_A0GHU7 Cluster: Short-chain dehydrogenase/reductase SDR
precursor; n=2; Burkholderia|Rep: Short-chain
dehydrogenase/reductase SDR precursor - Burkholderia
phytofirmans PsJN
Length = 255
Score = 54.8 bits (126), Expect = 2e-06
Identities = 52/169 (30%), Positives = 76/169 (44%), Gaps = 7/169 (4%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLC------AHTFPLD 285
+L VTG G+G A+AARLAR+G I +H TE A+A+ K A T +
Sbjct: 8 KLALVTGASRGIGAAIAARLARDGASVI--VHYASSTERAEAVVKEIRDAGGEAETVGAN 65
Query: 286 VTRVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGA 465
+++ E V+ + + + +VNNAG + G + + +S H NL
Sbjct: 66 LSKPEGVRSLIDSLSGAFGGRFEGRLDILVNNAGTVEYGPF--LDSSESSYDTHFNL--- 120
Query: 466 MRVISAFLPEIRKTAIETTSKPKPRIINVGSHCG-LQPLPAFAAYSASK 609
+ A + + A + RIINVGS G PLP Y ASK
Sbjct: 121 --NVRAPIKLAKDAAARMVAAGWGRIINVGSAFGEAAPLPGVTLYIASK 167
>UniRef50_O97166 Cluster: 3-alpha-hydroxysteroid dehydrogenase-like
protein; n=1; Branchiostoma floridae|Rep:
3-alpha-hydroxysteroid dehydrogenase-like protein -
Branchiostoma floridae (Florida lancelet) (Amphioxus)
Length = 273
Score = 54.8 bits (126), Expect = 2e-06
Identities = 43/154 (27%), Positives = 70/154 (45%), Gaps = 4/154 (2%)
Frame = +1
Query: 118 VSRLVAVTGCDSGLGWAVAARLARE--GFITIAGMHKGIETEAAKAL-EKLCAHTF-PLD 285
+SR+ VTG + G+G A+ L ++ G + + + EA K L E+ C F LD
Sbjct: 1 MSRVAVVTGANKGIGLAIVKGLCKQFDGTVYLTARDESKGQEAVKELNEQGCQPRFHQLD 60
Query: 286 VTRVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGA 465
V ++S+ F++++ + +VNNAGVM G +E + +N G
Sbjct: 61 VLSLDSIHRFKQHL-----EKEHQGLDVLVNNAGVMYGGSNPTPLVEQVEVTMGINFFGL 115
Query: 466 MRVISAFLPEIRKTAIETTSKPKPRIINVGSHCG 567
+ + A P + KP RI+NV S G
Sbjct: 116 LNLTKALTPLL---------KPHARIVNVSSGLG 140
>UniRef50_UPI0000E4A41A Cluster: PREDICTED: similar to Retinol
dehydrogenase 8 like; n=3; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to Retinol
dehydrogenase 8 like - Strongylocentrotus purpuratus
Length = 304
Score = 54.4 bits (125), Expect = 2e-06
Identities = 43/135 (31%), Positives = 68/135 (50%), Gaps = 8/135 (5%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREG------FITIAGMHKGIETEAAKALEKLCAHTF--P 279
++V +TGC +G+G A+A RLA + T+ M + E AA + L F
Sbjct: 4 QIVLITGCSAGIGLAIATRLALDRDQRYIVIATVIAMTEKAELVAAVG-DALYKTVFIQA 62
Query: 280 LDVTRVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLL 459
LDVT E++ YV+ + N + ++NNAG++ VG E + I+ VN +
Sbjct: 63 LDVTDDENIS----YVVNNVV-NTYGRIDVLINNAGLVVVGIPELIPREKIDQIFSVNAI 117
Query: 460 GAMRVISAFLPEIRK 504
G MRV A LP +++
Sbjct: 118 GTMRVTQAVLPHMKE 132
>UniRef50_Q89G53 Cluster: Bll6494 protein; n=13; Proteobacteria|Rep:
Bll6494 protein - Bradyrhizobium japonicum
Length = 285
Score = 54.4 bits (125), Expect = 2e-06
Identities = 45/164 (27%), Positives = 71/164 (43%), Gaps = 2/164 (1%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPL--DVTRV 297
R V VTG +G+GWA+A + G+ + K + +A + + A+ P+ DVT
Sbjct: 4 RSVVVTGASTGIGWAIAKFMVGRGYRVFGSVRK--QADADRLTGEFGANFTPVLFDVTDE 61
Query: 298 ESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVI 477
+V + V L +VNNAGV G ++ + +N++G +
Sbjct: 62 AAVLAAARNVREALGGE---TLAGLVNNAGVAVAGPVLELSVDDFRRQMDINVIGPVIAT 118
Query: 478 SAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
AF P + A + PK RI+ + S G P A Y SK
Sbjct: 119 QAFGPLL--GADPSLKGPKGRIVMISSVAGKNGNPLSAPYCTSK 160
>UniRef50_Q2BDF6 Cluster: Putative uncharacterized protein; n=1;
Bacillus sp. NRRL B-14911|Rep: Putative uncharacterized
protein - Bacillus sp. NRRL B-14911
Length = 260
Score = 54.4 bits (125), Expect = 2e-06
Identities = 41/172 (23%), Positives = 73/172 (42%), Gaps = 1/172 (0%)
Frame = +1
Query: 103 VSAMSVSRLVAVTGCDSGLGWAVAARLAREGF-ITIAGMHKGIETEAAKALEKLCAHTFP 279
+ + + + V +TG SGLG+ A +G+ + + +K E K + L T
Sbjct: 1 MEVLMMKKSVLITGATSGLGYDFVKLFAADGYDLVLVARNKAKLEEIKKEFQDLSVLTIS 60
Query: 280 LDVTRVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLL 459
D++ + +E + V +VNNAG +G + + + +N+
Sbjct: 61 KDLSIAGAAKEVYEEVSAA-----GISIDVLVNNAGFGLMGPFHELDIRKQAEMIQLNVT 115
Query: 460 GAMRVISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKSW 615
+ FLP ++ + K K RI+NV S QP P A Y A+K++
Sbjct: 116 ALTELTYHFLPGLK------SQKDKARILNVASTAAFQPGPLMAVYYATKAY 161
>UniRef50_A4C4K9 Cluster: Short-chain alcohol dehydrogenase-like
protein; n=1; Pseudoalteromonas tunicata D2|Rep:
Short-chain alcohol dehydrogenase-like protein -
Pseudoalteromonas tunicata D2
Length = 270
Score = 54.4 bits (125), Expect = 2e-06
Identities = 47/167 (28%), Positives = 78/167 (46%), Gaps = 1/167 (0%)
Frame = +1
Query: 112 MSVSRLVAVTGCDSGLGWAVAARLAREGF-ITIAGMHKGIETEAAKALEKLCAHTFPLDV 288
MS S L +TG G+G A+AA L +G+ + + G ++ + +K+L ++ D+
Sbjct: 1 MSKSPLCVLTGASGGIGQAMAAALHDQGYRLLLVGRNELKLAQLSKSLGNQHSY-ITADL 59
Query: 289 TRVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAM 468
+E V K ++NNAGV + ++ +A I + +NLL M
Sbjct: 60 ATIEGRDAL------VHKAQKLGGASVLINNAGVNQMASFDHQSAVDISKTLEMNLLVPM 113
Query: 469 RVISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
+ AFL ++ + K I+NVGS G P +A+Y ASK
Sbjct: 114 LLTQAFLAQL-------SQKDSATIVNVGSAFGSIGFPYYASYCASK 153
>UniRef50_A4BUN6 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Nitrococcus mobilis Nb-231|Rep: Short-chain
dehydrogenase/reductase SDR - Nitrococcus mobilis Nb-231
Length = 243
Score = 54.4 bits (125), Expect = 2e-06
Identities = 51/179 (28%), Positives = 79/179 (44%), Gaps = 16/179 (8%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKAL---EKLCAHTFPLDVTR 294
R+ +TG + GLG+ A +LAR G+ + ++ +AA E L PLDVTR
Sbjct: 6 RIAVITGANRGLGFETARQLARRGYKAVLTSRDAVQGKAAADKLQGEALDVGYHPLDVTR 65
Query: 295 VESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVM-----------TVGKYEWMTASMIESP 441
+SVQ ++ DN + +VNNAG+ +E S+ E+
Sbjct: 66 ADSVQRLAGFL-----DNAFGRLDVLVNNAGIFPEQASAHGAHSAPNVFEMPLESLHEN- 119
Query: 442 VHVNLLGAMRVISAFLPEIRKTAIETTSKPKPRIINVGSHCG--LQPLPAFAAYSASKS 612
+ N GA+R+I +P +R+ RI+N+ S G F AY SK+
Sbjct: 120 LQTNAFGALRLIQTIVPLMRRHGY-------GRIVNISSGYGQLAHMAHGFPAYRMSKA 171
>UniRef50_A4A4T0 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Congregibacter litoralis KT71|Rep: Short-chain
dehydrogenase/reductase SDR - Congregibacter litoralis
KT71
Length = 321
Score = 54.4 bits (125), Expect = 2e-06
Identities = 38/129 (29%), Positives = 59/129 (45%)
Frame = +1
Query: 106 SAMSVSRLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLD 285
S + R + VTG SG+G +A L+R GF AG K + EA ++ + LD
Sbjct: 25 SGATPQRAILVTGATSGIGKEIALTLSRRGFFVYAGARKSADIEALSKIDNM--RGIRLD 82
Query: 286 VTRVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGA 465
VT +Q + ++ + + H +VNNAGV ++ + + VN+ G
Sbjct: 83 VT----IQADIDAAVETIEQSGR-GLHGLVNNAGVFVFDPLIEVSERDMRFVMDVNVFGP 137
Query: 466 MRVISAFLP 492
RV AF P
Sbjct: 138 YRVTKAFAP 146
>UniRef50_A1VQT6 Cluster: Short-chain dehydrogenase/reductase SDR;
n=2; Proteobacteria|Rep: Short-chain
dehydrogenase/reductase SDR - Polaromonas
naphthalenivorans (strain CJ2)
Length = 286
Score = 54.4 bits (125), Expect = 2e-06
Identities = 51/177 (28%), Positives = 78/177 (44%), Gaps = 2/177 (1%)
Frame = +1
Query: 103 VSAMSVSRLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHT-FP 279
V+ + + VTG G+GWA A RLA +G + +A + + A+A E H
Sbjct: 13 VTPNPAAAVAIVTGAADGIGWATAQRLAADG-LRVALLDLRADAAQARAAELGSIHLGLG 71
Query: 280 LDVTRVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGV-MTVGKYEWMTASMIESPVHVNL 456
DVT ESV+ VL + A+VNNAG+ G + + + V+L
Sbjct: 72 CDVTSEESVEAAVAAVLERFG-----RIDALVNNAGIGDQTGPTTEQSVQAFDRVLAVHL 126
Query: 457 LGAMRVISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKSWPFGV 627
G + A + + A + + I+N+GS LPA AYSA K+ G+
Sbjct: 127 RGTFLMSRAVARHMLQAA-PVPGRGRGAIVNLGSIASSTGLPARNAYSAGKAGVLGM 182
>UniRef50_A1UG25 Cluster: Short-chain dehydrogenase/reductase SDR;
n=6; Mycobacterium|Rep: Short-chain
dehydrogenase/reductase SDR - Mycobacterium sp. (strain
KMS)
Length = 348
Score = 54.4 bits (125), Expect = 2e-06
Identities = 46/165 (27%), Positives = 73/165 (44%), Gaps = 3/165 (1%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLD---VTR 294
R V +TG GLG+A A RL REG+ +A M E A L + T D +
Sbjct: 14 RTVVITGASRGLGFASAVRLYREGWRVVAAMR--TPGECAALLREAAGATDDDDRLVCVQ 71
Query: 295 VESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRV 474
++ + L + +A+V+NAG+ G E + + +++G + +
Sbjct: 72 LDLMDTASVAAAAKLIEEAVGAPYALVHNAGISAAGVVEETDIELWQKMFATHVMGPVAL 131
Query: 475 ISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
A LP +R + RI+ V S G++ PA A YSA+K
Sbjct: 132 TKALLPSMRAAG-------RGRIVLVSSAGGVRGQPAIAPYSAAK 169
>UniRef50_A0BHQ0 Cluster: Chromosome undetermined scaffold_108,
whole genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_108,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 310
Score = 54.4 bits (125), Expect = 2e-06
Identities = 40/162 (24%), Positives = 70/162 (43%)
Frame = +1
Query: 130 VAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESVQ 309
V +TG G+G +A + +++GF I + EA + +H D + ++
Sbjct: 53 VCITGASDGIGKQLAMKFSQKGFKIILVARTRSKLEAVAQQLQTESHIIVADFAQSMDIK 112
Query: 310 EFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAFL 489
F K ++ + + V+NN G ++ ++ I + VN L + F+
Sbjct: 113 LFDK----IMDEVGERDVSIVINNVGADAFNRFHLISDEEIYKTIIVNCLPVTMLCKRFI 168
Query: 490 PEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKSW 615
P++ + K I+NV S G P P F YSASKS+
Sbjct: 169 PQLLRRRSH-----KSAIVNVTSLAGQIPTPYFNVYSASKSY 205
>UniRef50_A2BJK2 Cluster: Short chain dehydrogenase; n=1;
Hyperthermus butylicus DSM 5456|Rep: Short chain
dehydrogenase - Hyperthermus butylicus (strain DSM 5456
/ JCM 9403)
Length = 243
Score = 54.4 bits (125), Expect = 2e-06
Identities = 51/166 (30%), Positives = 80/166 (48%), Gaps = 4/166 (2%)
Frame = +1
Query: 127 LVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLC--AHTFPLDVTRVE 300
+V VTG G+G AVA AR G + + +AA+ +L A PL V
Sbjct: 7 VVLVTGSSRGIGRAVAVEAARRGAKGVVVNYVS-RRDAAEETARLVKEAGAVPLVVRADV 65
Query: 301 SV-QEFRKYVLTVLKDNPKY-KFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRV 474
SV +E RK V ++ K+ + VVNNAG++ +E M + + V+ GA+ V
Sbjct: 66 SVYEEARKLVEAAIE---KWGRLDVVVNNAGILEPKLFEDMKPRDWQRMIEVHFYGALNV 122
Query: 475 ISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKS 612
A +P +++ I+N+ S GL+P P + YSA+K+
Sbjct: 123 AHAAIPYMKRNGGGV-------IVNIASVLGLRPEPEASHYSAAKA 161
>UniRef50_P37959 Cluster: Uncharacterized oxidoreductase yusZ; n=4;
Bacillus|Rep: Uncharacterized oxidoreductase yusZ -
Bacillus subtilis
Length = 280
Score = 54.4 bits (125), Expect = 2e-06
Identities = 52/170 (30%), Positives = 69/170 (40%), Gaps = 8/170 (4%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCA--------HTFP 279
++ VTG SG G A +LAR F+ + E A+ L +L A H
Sbjct: 4 KIAIVTGASSGFGLLAAVKLARSFFVIATSR----QPEKAEQLRELAAAHNVSDSIHITA 59
Query: 280 LDVTRVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLL 459
LDVT +S+ F K V + +VNNAG G E + N+
Sbjct: 60 LDVTDEQSIVSFGKAV------SAYAPIDLLVNNAGTAYGGFIEDVPMEHFRQQFETNVF 113
Query: 460 GAMRVISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
G + V LP IRK +IINV S GL PA + Y +SK
Sbjct: 114 GVIHVTKTVLPYIRKHG-------GAKIINVSSISGLTGFPALSPYVSSK 156
>UniRef50_UPI0000584AC8 Cluster: PREDICTED: similar to retinol
dehydrogenase type III; n=3; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to retinol
dehydrogenase type III - Strongylocentrotus purpuratus
Length = 335
Score = 54.0 bits (124), Expect = 3e-06
Identities = 57/176 (32%), Positives = 78/176 (44%), Gaps = 4/176 (2%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREGFITIAG--MHKGIETEAAKALEKLCAHTFPLDVTRV 297
R V +TGCD+G G +A +L G IA KG T+ T LDVT
Sbjct: 54 RYVFITGCDTGFGNKLAKQLDIMGVHVIAACLTEKG-RTDLDDVTSDR-VKTLILDVTDH 111
Query: 298 ESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKY-EWMTASMIESPVHVNLLGAMRV 474
ESV + V ++ K VVNNAG+ + Y EW E + VNL G + V
Sbjct: 112 ESVLRAYEEVKKIIPH--KAALWGVVNNAGISNLAGYLEWTRREDYEKVLAVNLFGVVDV 169
Query: 475 ISAFLPEIRKTAIETTSKPKPRIINVGSHCG-LQPLPAFAAYSASKSWPFGVDTMS 639
FLP +++++ R++NV S G + LP Y SK F V+ S
Sbjct: 170 TLTFLPLLKESS--------GRLVNVASSAGRVSALP--GGYCESK---FAVEAFS 212
>UniRef50_Q9CBP7 Cluster: Possible short chain reductase; n=20;
Bacteria|Rep: Possible short chain reductase -
Mycobacterium leprae
Length = 312
Score = 54.0 bits (124), Expect = 3e-06
Identities = 47/165 (28%), Positives = 68/165 (41%), Gaps = 1/165 (0%)
Frame = +1
Query: 118 VSRLVAVTGCDSGLGWAVAARLAREGF-ITIAGMHKGIETEAAKALEKLCAHTFPLDVTR 294
V + VTG SG+G A A RLA G + + H + L A
Sbjct: 9 VGKRCFVTGAASGIGRATALRLAAYGAELYLTDRHCDGLAQTVSEARALGAQVPEYRALD 68
Query: 295 VESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRV 474
+ E + + +P V+N AGV G + +T + V +NL+G + +
Sbjct: 69 ISDYDEVAAFGADIHARHPSMDI--VMNIAGVSVWGTVDRLTHDQWSNVVAINLMGPIHI 126
Query: 475 ISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
I F+P I + ++NV S GL LP AAYSASK
Sbjct: 127 IETFVPAI------LAAGRGGHLVNVSSAAGLVALPWHAAYSASK 165
>UniRef50_Q9A477 Cluster: Short chain dehydrogenase family protein;
n=3; Alphaproteobacteria|Rep: Short chain dehydrogenase
family protein - Caulobacter crescentus (Caulobacter
vibrioides)
Length = 270
Score = 54.0 bits (124), Expect = 3e-06
Identities = 48/161 (29%), Positives = 73/161 (45%), Gaps = 1/161 (0%)
Frame = +1
Query: 130 VAVTGCDSGLGWAVAARLAREG-FITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESV 306
+ +TG SG+G A A R A+EG F+ ++ + K A A+ PLDV E+
Sbjct: 15 IFITGAASGIGLACAKRFAQEGWFVGLSDIDKVGLKAALLAVGPENGSIHPLDVRDREAW 74
Query: 307 QEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAF 486
+ + K +A++NNAGV G M+ + + + +NL G + A
Sbjct: 75 EN----AIGEFGRETGGKANALLNNAGVARFGMLNEMSDADCDIQIDINLKGVINGARAG 130
Query: 487 LPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
LP ++ R+INV S GL P A YSA+K
Sbjct: 131 LPLLKAAG--------GRLINVASCAGLYGSPKLAVYSATK 163
>UniRef50_A1ZYN0 Cluster: Dehydrogenase/reductase SDR family member
9; n=1; Microscilla marina ATCC 23134|Rep:
Dehydrogenase/reductase SDR family member 9 -
Microscilla marina ATCC 23134
Length = 280
Score = 54.0 bits (124), Expect = 3e-06
Identities = 41/164 (25%), Positives = 73/164 (44%), Gaps = 2/164 (1%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPL--DVTRV 297
+ + +TG +G+G+ + G+ + + K + +A K + PL DV+
Sbjct: 2 KTILITGASTGIGYGCVKEFHQRGYQVLGSVRK--QADADKLSSEFGDRFIPLLFDVSNP 59
Query: 298 ESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVI 477
E++Q+ + V +L + + ++NNAG+ G S I VN+ G ++V
Sbjct: 60 EAIQQAVQQVEQILGN--EQGLAGLINNAGIALGGPLALQPMSDIRQHFEVNVFGLIQVT 117
Query: 478 SAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
AFLP + + K I+N+ S G P AY A+K
Sbjct: 118 QAFLPLLGARKNHPVAPGK--ILNISSVGGKVGAPFIGAYVATK 159
>UniRef50_A0Z5T7 Cluster: 3-ketoacyl-(Acyl-carrier-protein)
reductase; n=2; unclassified Gammaproteobacteria
(miscellaneous)|Rep: 3-ketoacyl-(Acyl-carrier-protein)
reductase - marine gamma proteobacterium HTCC2080
Length = 248
Score = 54.0 bits (124), Expect = 3e-06
Identities = 45/159 (28%), Positives = 73/159 (45%)
Frame = +1
Query: 136 VTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESVQEF 315
+TG G+G A+AAR +G + + +G E + L A DV+ V + Q
Sbjct: 13 ITGASRGIGAAIAARAHEQGCRVVV-IARGEEAISTAGRLGLGAIAIQADVSDVAAAQSA 71
Query: 316 RKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAFLPE 495
+ + VVNNAGV GK E ++ ++ ++VNL GA+ +I A P
Sbjct: 72 VDETIATFG-----RIDVVVNNAGVHRGGKVERLSPEDWQTVLNVNLTGALNMIRAAKPH 126
Query: 496 IRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKS 612
+ + IIN+G+ G + P AY++SK+
Sbjct: 127 MGSGS---------SIINIGAVVGFRGFPGDVAYASSKA 156
>UniRef50_Q4A054 Cluster: Uncharacterized oxidoreductase SSP0419;
n=15; Staphylococcus|Rep: Uncharacterized oxidoreductase
SSP0419 - Staphylococcus saprophyticus subsp.
saprophyticus (strain ATCC 15305 /DSM 20229)
Length = 234
Score = 54.0 bits (124), Expect = 3e-06
Identities = 47/168 (27%), Positives = 76/168 (45%), Gaps = 5/168 (2%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREGF-ITIAGMHKGIETEAAKALE---KLCAHTFPLDVT 291
++ VTG SG+G ++A LA +G + + G + E AK ++ + T +DVT
Sbjct: 7 KVAVVTGASSGIGASIAETLANQGVKVVLTGRDESRLAEVAKRIQDNKQAVVETSIVDVT 66
Query: 292 RVESVQEFRKYVLTVLKDNPKY-KFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAM 468
E V E V K K+ + +VN+AG+M E+ + VN+ G +
Sbjct: 67 HKEEVTEL------VEKTKEKFGQIDILVNSAGLMLSSAITEGDVEAWEAMIDVNIKGTL 120
Query: 469 RVISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKS 612
I+A LP + ++ IIN+ S G + YSASK+
Sbjct: 121 YTINAVLPSM-------LNQSSGHIINIASISGFEVTKKSTLYSASKA 161
>UniRef50_P66778 Cluster: Probable oxidoreductase ephD; n=16;
Mycobacterium|Rep: Probable oxidoreductase ephD -
Mycobacterium bovis
Length = 592
Score = 54.0 bits (124), Expect = 3e-06
Identities = 52/165 (31%), Positives = 78/165 (47%), Gaps = 3/165 (1%)
Frame = +1
Query: 127 LVAVTGCDSGLGWAVAARLAREGF-ITIAGMHKGI--ETEAAKALEKLCAHTFPLDVTRV 297
LV+VTG SG+G A AREG I I+ + + +T A A A+ + LDV+
Sbjct: 326 LVSVTGAGSGIGRETALAFAREGAEIVISDIDEATVKDTAAEIAARGGIAYPYVLDVSDA 385
Query: 298 ESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVI 477
E+V+ F + V + P VVNNAG+ G++ A + + VNL G +
Sbjct: 386 EAVEAFAERV-SAEHGVP----DIVVNNAGIGQAGRFLDTPAEQFDRVLAVNLGGVVNGC 440
Query: 478 SAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKS 612
AF + +E + I+NV S PL + +AY SK+
Sbjct: 441 RAF----GQRLVERGT--GGHIVNVSSMAAYAPLQSLSAYCTSKA 479
>UniRef50_UPI000058485A Cluster: PREDICTED: similar to retinol
dehydrogenase 8; n=10; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to retinol
dehydrogenase 8 - Strongylocentrotus purpuratus
Length = 288
Score = 53.6 bits (123), Expect = 4e-06
Identities = 54/179 (30%), Positives = 88/179 (49%), Gaps = 8/179 (4%)
Frame = +1
Query: 118 VSRLVAVTGCDSGLGWAVAARLA---REGFITIAG---MHKGIETEAA--KALEKLCAHT 273
V ++V +TGC +G+G A A RLA + +I IA M + E AA AL+K
Sbjct: 2 VPQIVLITGCSAGIGLATAKRLAFDVDQRYIVIATVIVMSEKAELVAAVGDALDK-TVFI 60
Query: 274 FPLDVTRVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVN 453
LDVT +++ + + V+ V + + ++N AG+ E +T I+ +VN
Sbjct: 61 RELDVTNDKNISDVVRDVIRV-----QGRIDILINVAGLAFNEIPERVTREQIDKLFNVN 115
Query: 454 LLGAMRVISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKSWPFGVD 630
+G +R+ A LP +++ + +I+ V S Q P F YSA+K FGV+
Sbjct: 116 TIGPIRLAQAVLPHMKE-------RQAGKIVTVSSDMSRQAWPYFDIYSATK---FGVE 164
>UniRef50_Q6PC70 Cluster: Retinol dehydrogenase 8; n=14;
Euteleostomi|Rep: Retinol dehydrogenase 8 - Danio rerio
(Zebrafish) (Brachydanio rerio)
Length = 318
Score = 53.6 bits (123), Expect = 4e-06
Identities = 49/169 (28%), Positives = 79/169 (46%), Gaps = 7/169 (4%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREG---FITIAGMH----KGIETEAAKALEKLCAHTFPL 282
++V +TGC SG+G +A LAR+ + IA M K EAA + PL
Sbjct: 8 KVVLITGCSSGIGLRIAVLLARDEQKRYHVIATMRDLKKKDRLVEAAGEVYGQTLTLLPL 67
Query: 283 DVTRVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLG 462
D+ ESV++ + +KD ++NNAGV +G E ++ ++ N G
Sbjct: 68 DICSDESVRQ----CVNSVKDR---HIDVLINNAGVGLLGPVESISMDEMKRVFETNFFG 120
Query: 463 AMRVISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
+R+I +P+++K + II + S GLQ + Y+ASK
Sbjct: 121 TVRMIKEVMPDMKK-------RQAGHIIIMSSVMGLQGVVFNDVYTASK 162
>UniRef50_Q8ELB7 Cluster: Oxidoreductase; n=1; Oceanobacillus
iheyensis|Rep: Oxidoreductase - Oceanobacillus iheyensis
Length = 248
Score = 53.6 bits (123), Expect = 4e-06
Identities = 45/165 (27%), Positives = 81/165 (49%), Gaps = 1/165 (0%)
Frame = +1
Query: 121 SRLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLC-AHTFPLDVTRV 297
++++ VTG + G G A+A LA G I G+ + +A + E + AH FP+ +
Sbjct: 6 NQVILVTGANRGQGKAIAQHLASLG--AIVGVAARKDEDAQEVAEMIGEAHAFPVQLDVT 63
Query: 298 ESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVI 477
+ + E++ V ++ N + +VNNAG + ++ T + ++VN LG +
Sbjct: 64 KEL-EWKTAVDEII--NKFGRLDVLVNNAGALKRKPFKETTLDDYQQLINVNQLGVFMGM 120
Query: 478 SAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKS 612
A +P++ K + K IIN S P+ +AY+A+KS
Sbjct: 121 QAVIPQMEK-------QQKGSIINNVSISAFAPISQSSAYAATKS 158
>UniRef50_Q1GSP0 Cluster: Short-chain dehydrogenase/reductase SDR
precursor; n=5; Alphaproteobacteria|Rep: Short-chain
dehydrogenase/reductase SDR precursor - Sphingopyxis
alaskensis (Sphingomonas alaskensis)
Length = 329
Score = 53.6 bits (123), Expect = 4e-06
Identities = 51/179 (28%), Positives = 75/179 (41%), Gaps = 7/179 (3%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREGFITIAGMH-------KGIETEAAKALEKLCAHTFPL 282
R + +TGC SG G A AR G IA M + + EAAK +KL +
Sbjct: 38 RTILITGCSSGFGRIGALHYARLGAKVIATMRGLPRPEAESLAAEAAK--DKLDLDIVEI 95
Query: 283 DVTRVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLG 462
DVT SV L + + +VNNAG+ G E + N+ G
Sbjct: 96 DVTSDASVASGTAKALAIAGG----RIDTLVNNAGIGITGPVEVQDMEATQLIFDTNVFG 151
Query: 463 AMRVISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKSWPFGVDTMS 639
R++ A LP++R + ++ N+ S G +P YSA+K F V+ +S
Sbjct: 152 IQRMLRALLPQMR-------AAKGGQVFNISSQLGRVIVPGGGHYSATK---FAVEALS 200
>UniRef50_Q0LKA9 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Herpetosiphon aurantiacus ATCC 23779|Rep:
Short-chain dehydrogenase/reductase SDR - Herpetosiphon
aurantiacus ATCC 23779
Length = 258
Score = 53.6 bits (123), Expect = 4e-06
Identities = 48/161 (29%), Positives = 70/161 (43%), Gaps = 3/161 (1%)
Frame = +1
Query: 136 VTGCDSGLGWAVAARLAREGF-ITIAGMHKGIETEAAKALEKLCAHTFPL--DVTRVESV 306
+TG SG+G +A LAR G + +A E A A+ + A + DV+ ++V
Sbjct: 10 ITGASSGIGKLIAEGLARGGANVVLAARSAEQLNELAAAINQTGAKALAVATDVSDAQAV 69
Query: 307 QEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAF 486
Q + + + ++NNAG E + IE + VN GAM I A
Sbjct: 70 QALVEQAVATFG-----RVDLLINNAGYGVFDSIEQIEWKHIEGMITVNYFGAMHCIRAV 124
Query: 487 LPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
LP +RK + I+NV S GL +YSASK
Sbjct: 125 LPVMRK-------QNSGHIVNVASVAGLVSTHNMGSYSASK 158
>UniRef50_A5FZ99 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Acidiphilium cryptum JF-5|Rep: Short-chain
dehydrogenase/reductase SDR - Acidiphilium cryptum
(strain JF-5)
Length = 265
Score = 53.6 bits (123), Expect = 4e-06
Identities = 46/166 (27%), Positives = 72/166 (43%)
Frame = +1
Query: 115 SVSRLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTR 294
S +V +TG SG+G A+A +G+ + E A P DVT
Sbjct: 6 SADGIVWITGASSGIGRALAEAHVAQGWRVAITARREAELRALAETHPSRIIVAPADVTD 65
Query: 295 VESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRV 474
+SV+E V T+ +D P + + NAG E TA + V +NLLG R
Sbjct: 66 PDSVREA---VNTITRDGPIAR---AILNAGTYERDTAETFTADRLRRQVELNLLGTARG 119
Query: 475 ISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKS 612
+ +P + ++ + +I + S GL LP +YSA+K+
Sbjct: 120 LELVMPAM-------IARKRGQIALMSSLAGLAGLPGSVSYSATKA 158
>UniRef50_A4BRT2 Cluster: Probable oxidoreductase; n=1; Nitrococcus
mobilis Nb-231|Rep: Probable oxidoreductase -
Nitrococcus mobilis Nb-231
Length = 256
Score = 53.6 bits (123), Expect = 4e-06
Identities = 44/162 (27%), Positives = 69/162 (42%), Gaps = 1/162 (0%)
Frame = +1
Query: 130 VAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESVQ 309
V VTG G+G A+ A G+ I G++ AAK AH D+ R +
Sbjct: 4 VIVTGAAGGIGQALVRAFAEAGYPVI-----GVDL-AAKPERLPTAHYIQCDLARTVAEP 57
Query: 310 EFRKYVLTVLKDN-PKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAF 486
+ + + + ++ F A++NNA V +GK E + + VNLL A
Sbjct: 58 TYAEEIFSTIRTTLDGQPFDALINNAAVQILGKVEGLNRDAWHRTLDVNLLAPFLWAQAL 117
Query: 487 LPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKS 612
LPE+ + K ++N+ S P F AY+ SK+
Sbjct: 118 LPELEEA--------KGCVLNISSIHARLTKPEFVAYATSKA 151
>UniRef50_Q2QLP7 Cluster: Oxidoreductase, short chain
dehydrogenase/reductase family protein, expressed; n=1;
Oryza sativa (japonica cultivar-group)|Rep:
Oxidoreductase, short chain dehydrogenase/reductase
family protein, expressed - Oryza sativa subsp. japonica
(Rice)
Length = 302
Score = 53.6 bits (123), Expect = 4e-06
Identities = 48/163 (29%), Positives = 72/163 (44%), Gaps = 1/163 (0%)
Frame = +1
Query: 127 LVAVTGC-DSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVES 303
+V +TGC + G+G+ A G +A + L L A PLDVT ES
Sbjct: 19 VVLITGCANGGIGYEYCKAFASLGCRVVATD----VPDRVPDLAGLDADHLPLDVTSDES 74
Query: 304 VQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISA 483
V+ V VL ++ + +VNNAG+ G + + + VN LG +R++ A
Sbjct: 75 VEGA---VARVLAEHGRVD--VLVNNAGIGCTGPLAELRGEAVRRAMDVNFLGQLRMVRA 129
Query: 484 FLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKS 612
P + S+ R++NVGS G P Y ASK+
Sbjct: 130 VAPHM-------ASRRSGRVVNVGSVVGTAATPWAGPYCASKA 165
>UniRef50_A7RGK5 Cluster: Predicted protein; n=4; Eumetazoa|Rep:
Predicted protein - Nematostella vectensis
Length = 275
Score = 53.6 bits (123), Expect = 4e-06
Identities = 45/174 (25%), Positives = 73/174 (41%), Gaps = 4/174 (2%)
Frame = +1
Query: 109 AMSVSRLVAVTGCDSGLGWAVAARLARE--GFITIAGMHKGIETEAAKAL--EKLCAHTF 276
A S SR+ VTG + G+G+A+ L ++ G + + ++ + EA L E L
Sbjct: 2 AASPSRVAVVTGSNKGIGFAIVRGLCKQFSGTVILTARNENLGKEAVDKLKEEGLNPVFH 61
Query: 277 PLDVTRVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNL 456
LD+T ES+ + R Y+ + K ++NNAG+ G + E N
Sbjct: 62 QLDITSQESINKLRDYLSSTYKG-----LDLLINNAGIAYKGASIAPFSEQAEVTARTNF 116
Query: 457 LGAMRVISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKSWP 618
G + + P +R P R++NV S GL + A A + P
Sbjct: 117 TGTLNICDTLFPLLR---------PHARVVNVASLAGLLKIIPSEAIKAKFTSP 161
>UniRef50_Q9Y8Y1 Cluster: 3-oxoacyl-[acyl-carrier-protein]
reductase; n=3; Desulfurococcales|Rep:
3-oxoacyl-[acyl-carrier-protein] reductase - Aeropyrum
pernix
Length = 250
Score = 53.6 bits (123), Expect = 4e-06
Identities = 53/170 (31%), Positives = 75/170 (44%), Gaps = 6/170 (3%)
Frame = +1
Query: 136 VTGCDSGLGWAVAARLAREGFITIAGMHKGIE-----TEAAKALEKLCAHTFPLDVTRVE 300
VTG G+G A R AREG+ + + E A+ L A+T +DV +
Sbjct: 8 VTGGSRGIGRATVLRFAREGWSVVIAYKSRADLAEKTAEEARRLGSPEAYTVRVDVGDPD 67
Query: 301 SVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVIS 480
SV E V ++ + +VN AGV+ +G E + S E + VNL G V
Sbjct: 68 SVTEMSSRVGELIPH-----LNVLVNAAGVLQLGGIEETSISEWEETLRVNLTGVYLVTK 122
Query: 481 AFLPEIRKTAIETTSKPKPRIINVGSHCG-LQPLPAFAAYSASKSWPFGV 627
LP +RK + I+NV S G + A AYSASK+ G+
Sbjct: 123 LLLPLLRKAKWAS-------IVNVASIAGETGNVVAGVAYSASKAGVIGL 165
>UniRef50_UPI0000E4927A Cluster: PREDICTED: similar to retinol
dehydrogenase 8; n=2; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to retinol dehydrogenase 8 -
Strongylocentrotus purpuratus
Length = 279
Score = 53.2 bits (122), Expect = 5e-06
Identities = 48/169 (28%), Positives = 82/169 (48%), Gaps = 8/169 (4%)
Frame = +1
Query: 127 LVAVTGCDSGLGWAVAARLAREG---FITIAGMHKGIETE---AAKALEKLCAHTFPL-- 282
+V ++GC SG+G A A LA + F+ A + K +E E +A + L FPL
Sbjct: 4 IVLISGCSSGIGLATAQLLAHDSQKRFLVYATILKPLEQEEQFRLQAGDALNDTLFPLQV 63
Query: 283 DVTRVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLG 462
DVT+ + + V TV+K + + +++ AGV + E ++ +++ +N G
Sbjct: 64 DVTKEAMIVD---AVATVMKKHG--RIDVLISIAGVNILNVTEAISLDVMKRVFDINFFG 118
Query: 463 AMRVISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
+R+ +P ++K + RIIN+GS GL P Y A+K
Sbjct: 119 MVRIAQEVIPGMKK-------QRSGRIINMGSIHGLGAFPYMGIYGATK 160
>UniRef50_UPI000038D7DD Cluster: COG1028: Dehydrogenases with
different specificities (related to short-chain alcohol
dehydrogenases); n=1; Nostoc punctiforme PCC 73102|Rep:
COG1028: Dehydrogenases with different specificities
(related to short-chain alcohol dehydrogenases) - Nostoc
punctiforme PCC 73102
Length = 281
Score = 53.2 bits (122), Expect = 5e-06
Identities = 43/162 (26%), Positives = 73/162 (45%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVES 303
+ V +TG SG+G A++G+ A M + + + + + LDVT S
Sbjct: 3 KTVFITGTSSGIGKFTTIYFAQQGWNVAATMRNPSQDQNFREFPNI--KVYFLDVTDNNS 60
Query: 304 VQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISA 483
+Q + + ++D + +VNNAG G +E MT +I + N+ G MR+ A
Sbjct: 61 IQTA---IASAIQDFGQ--IDVLVNNAGYGVDGVFEAMTDEIIAKQFNTNVFGLMRITQA 115
Query: 484 FLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
+P +R+ T II + S G P ++ Y +SK
Sbjct: 116 IIPHLRQQGGGT-------IIQIASMGGRITFPLYSIYHSSK 150
>UniRef50_Q4K8K3 Cluster: Oxidoreductase, short chain
dehydrogenase/reductase family; n=18; Pseudomonas|Rep:
Oxidoreductase, short chain dehydrogenase/reductase
family - Pseudomonas fluorescens (strain Pf-5 / ATCC
BAA-477)
Length = 313
Score = 53.2 bits (122), Expect = 5e-06
Identities = 46/163 (28%), Positives = 81/163 (49%), Gaps = 4/163 (2%)
Frame = +1
Query: 136 VTGCDSGLGWAVAARLAREGF-ITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESVQE 312
+TG SGLG +A R AREG+ + ++ + + E K + F V R + V++
Sbjct: 49 ITGAGSGLGREIALRWAREGWRLALSDVSEAGLQETLKLVRAAGGDGF---VQRCD-VRD 104
Query: 313 FRKYVLTVLKDNPKYKFHAV---VNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISA 483
+ + LT + KF + VNNAGV + G + ++ + + +NL+G ++ A
Sbjct: 105 YSQ--LTAFAQACEVKFGGIDIIVNNAGVASGGFFSELSLEDWDWQIAINLMGVVKGCKA 162
Query: 484 FLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKS 612
FLP + ++ K +IIN+ S L PA + Y+ +K+
Sbjct: 163 FLPLLEQS--------KGKIINIASMAALMQGPAMSNYNVAKA 197
>UniRef50_Q2IK95 Cluster: Short-chain dehydrogenase/reductase SDR
precursor; n=1; Anaeromyxobacter dehalogenans 2CP-C|Rep:
Short-chain dehydrogenase/reductase SDR precursor -
Anaeromyxobacter dehalogenans (strain 2CP-C)
Length = 286
Score = 53.2 bits (122), Expect = 5e-06
Identities = 46/163 (28%), Positives = 78/163 (47%), Gaps = 3/163 (1%)
Frame = +1
Query: 130 VAVTGCDSGLGWAVAARL-AREGFITIAGMHKGIETEAAKALEKL--CAHTFPLDVTRVE 300
V +TG +G+G A+A RL AR + + + A A+ + A LDVT+
Sbjct: 9 VLITGAAAGIGRALAERLGARGAALILTDRDEEPLAATADAIRRAGAVAEHHVLDVTKGA 68
Query: 301 SVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVIS 480
++ + R + + + P +VNNAGV+ G + + VN+LG + V
Sbjct: 69 AILQVRDAIHS--RGGP---IDVLVNNAGVVFGGAFADVPLQKHLDTFAVNVLGLVSVTH 123
Query: 481 AFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
AFL ++ ++P+ ++NV S GL +P + Y+ASK
Sbjct: 124 AFLDDL-------VARPEAHLVNVASAAGLTAVPFASTYAASK 159
>UniRef50_Q28P30 Cluster: Short-chain dehydrogenase/reductase SDR;
n=2; Rhodobacteraceae|Rep: Short-chain
dehydrogenase/reductase SDR - Jannaschia sp. (strain
CCS1)
Length = 257
Score = 53.2 bits (122), Expect = 5e-06
Identities = 52/167 (31%), Positives = 75/167 (44%), Gaps = 3/167 (1%)
Frame = +1
Query: 136 VTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCA---HTFPLDVTRVESV 306
VTG SG+G A+A RLAR+G + G +T+ K + A H LDV ESV
Sbjct: 10 VTGGLSGMGLAIARRLARDGTTVVIGARSAGDTDYVKDVLGTDADGLHAEQLDVQSHESV 69
Query: 307 QEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAF 486
F V +V+K + +VN AGV + + ++ NL G R I A
Sbjct: 70 DGF---VASVVKTHGGVDI--LVNAAGVYEEAAVIDHPEQIWDDHINTNLSGTFRTIRAV 124
Query: 487 LPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKSWPFGV 627
+P +++ RIIN+ S + AAY ASK+ G+
Sbjct: 125 MPHMKRAG-------WGRIINMASVAAHNGMANNAAYCASKAGLLGL 164
>UniRef50_Q15UE4 Cluster: 3-hydroxybutyrate dehydrogenase precursor;
n=12; Proteobacteria|Rep: 3-hydroxybutyrate
dehydrogenase precursor - Pseudoalteromonas atlantica
(strain T6c / BAA-1087)
Length = 261
Score = 53.2 bits (122), Expect = 5e-06
Identities = 48/165 (29%), Positives = 71/165 (43%), Gaps = 3/165 (1%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREGF-ITIAGMHKGIETEAAKAL--EKLCAHTFPLDVTR 294
R + +TG SG+G +A +L G I IA M+ A L + + A LDVT
Sbjct: 10 RTILITGGASGIGLGIAQQLGSNGHKIVIADMNMDAAENAVAELGAQGISARALLLDVTN 69
Query: 295 VESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRV 474
E + + D ++NNAG+ V K E + +++ L+ +
Sbjct: 70 QEHINNLSANLAPDTVD-------VLINNAGIQHVAKLEEFPGDKWQQLINIMLVAPAML 122
Query: 475 ISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
A LP +R SK RIIN+GS L P +AY A+K
Sbjct: 123 TQALLPTMR-------SKNYGRIINIGSVHSLIASPYKSAYVAAK 160
>UniRef50_Q0FWE7 Cluster: Short-chain alcohol dehydrogenase; n=2;
Alphaproteobacteria|Rep: Short-chain alcohol
dehydrogenase - Roseovarius sp. HTCC2601
Length = 242
Score = 53.2 bits (122), Expect = 5e-06
Identities = 53/163 (32%), Positives = 73/163 (44%), Gaps = 1/163 (0%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVES 303
R + VTG SG+G AVA +EG G EA L + LD+T E+
Sbjct: 11 RRIVVTGAASGIGKAVAELFRQEGAALALLDLDGAGAEAT--LGEGEGLGIGLDITDAEA 68
Query: 304 VQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISA 483
V++ L VVN AG+M GK M A + VNL G VI A
Sbjct: 69 VEQSIDRAAEALGG-----IDGVVNAAGIMLTGKLLEMPAEAWRKQIDVNLNGTYLVIRA 123
Query: 484 FLPEIRKTAIETTSKPKPRIINVGSHCGLQP-LPAFAAYSASK 609
LP +++ ET + ++N+ S GL P P ++Y+ASK
Sbjct: 124 CLPFLQR---ETGA----TVVNIASAQGLLPNAPGLSSYAASK 159
>UniRef50_A7GTG0 Cluster: Amino acid adenylation domain; n=2;
Firmicutes|Rep: Amino acid adenylation domain - Bacillus
cereus subsp. cytotoxis NVH 391-98
Length = 2031
Score = 53.2 bits (122), Expect = 5e-06
Identities = 52/171 (30%), Positives = 77/171 (45%), Gaps = 3/171 (1%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREGF-ITIAGMHKGIETEAAKALEKLCAH--TFPLDVTR 294
++ VTG G+G A+A +A+EG + I + E A + KL P D+
Sbjct: 1786 KVAIVTGGGRGIGRAIAISMAQEGASVAIVSRTEHQLDETACEIRKLGIEPLVIPGDIGE 1845
Query: 295 VESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRV 474
VQ K TV K K VVNNAG+ VG +T+ + + VN+ G +
Sbjct: 1846 WNDVQHIVK---TVSKQFGKIDI--VVNNAGITKVGSVTDVTSEEWKEIIRVNVFGTYHM 1900
Query: 475 ISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKSWPFGV 627
A +P + IE + +IIN+GS P +AY+ASK G+
Sbjct: 1901 CRATIPYL----IE---QKCGKIINIGSDSSFIGYPFMSAYAASKHGVLGL 1944
>UniRef50_A6UFZ1 Cluster: Short-chain dehydrogenase/reductase SDR;
n=2; Bacteria|Rep: Short-chain dehydrogenase/reductase
SDR - Sinorhizobium medicae WSM419
Length = 299
Score = 53.2 bits (122), Expect = 5e-06
Identities = 45/169 (26%), Positives = 72/169 (42%), Gaps = 1/169 (0%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREGFITIAGMHKG-IETEAAKALEKLCAHTFPLDVTRVE 300
++V +TG SG G A R AREG + +G + E A+ L A ++ V
Sbjct: 9 KVVVITGASSGFGKGAARRFAREGCSLVLAARRGNLLDELARECRSLGAPALAIEAD-VS 67
Query: 301 SVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVIS 480
+ + L + + VNNAGV +G +E + V NLLG +
Sbjct: 68 DRERVARLASAALAEYGRIDIW--VNNAGVGAIGPFEDIPLEDQAKVVETNLLGTLYGSF 125
Query: 481 AFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKSWPFGV 627
+ R+ + +IN+ S G + +P +AAY+ASK G+
Sbjct: 126 HAYRQFRQ-------QGSGILINIASELGRETVPYYAAYTASKHGVIGL 167
>UniRef50_A5UVY6 Cluster: Short-chain dehydrogenase/reductase SDR
precursor; n=3; Bacteria|Rep: Short-chain
dehydrogenase/reductase SDR precursor - Roseiflexus sp.
RS-1
Length = 269
Score = 53.2 bits (122), Expect = 5e-06
Identities = 51/165 (30%), Positives = 77/165 (46%), Gaps = 3/165 (1%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREG-FITIAGMHK-GIE-TEAAKALEKLCAHTFPLDVTR 294
R VTG SG+G AVA LAR + + +++ G+E T A A + LDV
Sbjct: 6 RTAVVTGAASGIGRAVAVSLARRRCHLALVDINQAGLEHTAALVATHGVRVSCHRLDVAD 65
Query: 295 VESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRV 474
+V V + +VN+AGV G +E ++A+ E +N+ G +R+
Sbjct: 66 AAAVAALPDAVCHI-----HASVDVLVNSAGVAVWGTFEQVSAADFEWLFGINVHGLVRM 120
Query: 475 ISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
AFLP ++ + R++NV S GL AAY+ASK
Sbjct: 121 TRAFLPLLK-------ASDDARLVNVSSVYGLVAPAGQAAYAASK 158
>UniRef50_A4BV46 Cluster: Putative ketoreductase; n=1; Nitrococcus
mobilis Nb-231|Rep: Putative ketoreductase - Nitrococcus
mobilis Nb-231
Length = 275
Score = 53.2 bits (122), Expect = 5e-06
Identities = 42/165 (25%), Positives = 80/165 (48%), Gaps = 6/165 (3%)
Frame = +1
Query: 136 VTGCDSGLGWAVAARLAREGF-ITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESV-- 306
+TG +G+G A+A AR+G +T++ + E A+ +E + P D V+ +
Sbjct: 10 ITGAGNGVGRAIAVAFARKGVRLTLSDRFEQRLRETAQQVEDVSREERPDDTPEVQLIPS 69
Query: 307 ---QEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVI 477
+R+ V+ ++ + +VNN V+ G+ E + A + + + NL+ +
Sbjct: 70 DVPDSWRERVIRMVLERFG-TLDILVNNVSVVQGGRLEKIEAEQLRAQLDANLVAPIYYT 128
Query: 478 SAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKS 612
A LP ++++ + IINV S GL LP + Y+A+K+
Sbjct: 129 RAALPALKESG-------EAAIINVSSVLGLVGLPFYTVYTAAKA 166
>UniRef50_A3VG77 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Rhodobacterales bacterium HTCC2654|Rep: Short-chain
dehydrogenase/reductase SDR - Rhodobacterales bacterium
HTCC2654
Length = 274
Score = 53.2 bits (122), Expect = 5e-06
Identities = 44/159 (27%), Positives = 72/159 (45%)
Frame = +1
Query: 136 VTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESVQEF 315
+TG GLG A+AA G I + G A ++L H +D+ + + +
Sbjct: 6 ITGVSRGLGQAIAAAALAAGDRVIGTVRNGT-AHVENAGDRL--HLLTVDLAKPGAAEAA 62
Query: 316 RKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAFLPE 495
+ L+V + VVNNAG +G + +T +E+ V++ +R+ LP
Sbjct: 63 ARQALSV-----HGRIDIVVNNAGFGVIGALDDLTDDQLETLFEVDVFAGIRICRTLLPH 117
Query: 496 IRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKS 612
IR + RI+N+ S G P A AAY+A+K+
Sbjct: 118 IR-------VQGAGRILNITSVAGRAPGAATAAYAAAKA 149
>UniRef50_A1UGA6 Cluster: Short-chain dehydrogenase/reductase SDR;
n=3; Mycobacterium|Rep: Short-chain
dehydrogenase/reductase SDR - Mycobacterium sp. (strain
KMS)
Length = 248
Score = 53.2 bits (122), Expect = 5e-06
Identities = 49/166 (29%), Positives = 71/166 (42%), Gaps = 2/166 (1%)
Frame = +1
Query: 118 VSRLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLC-AHTFPLDVTR 294
++R+ VTG + GLG A A LAR +A G +E A LDV
Sbjct: 1 MARIALVTGANRGLGRATALALARNKIRVVAASRNGASGVVDDIVEAGGEAIAVQLDVAD 60
Query: 295 VESVQEFRKYVLT-VLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMR 471
+ SV+ R L + ++ +VNNAGV +T ++ VN+ G +
Sbjct: 61 LSSVEAARVAALAGIGQEWNASTIDVLVNNAGVGLFAPLGAITVEDFDATFAVNVRGPLF 120
Query: 472 VISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
V AFLP + + A I+NV S PA + Y+ASK
Sbjct: 121 VTQAFLPHLSEGA---------SIVNVSSSLSRHVSPAASVYAASK 157
>UniRef50_A0Z6U9 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; marine gamma proteobacterium HTCC2080|Rep:
Short-chain dehydrogenase/reductase SDR - marine gamma
proteobacterium HTCC2080
Length = 255
Score = 53.2 bits (122), Expect = 5e-06
Identities = 47/163 (28%), Positives = 77/163 (47%), Gaps = 2/163 (1%)
Frame = +1
Query: 130 VAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESVQ 309
V +TG + G+G A+A ++GF I K + A L+K+ LD+T SV
Sbjct: 35 VLITGANRGIGLALARHFHQQGFAVIPTARK---PDEALELKKIGVEILQLDITDPASV- 90
Query: 310 EFRKYVLTVLKDNPKYKFHAVVNNAGV--MTVGKYEWMTASMIESPVHVNLLGAMRVISA 483
EF K + LK+ +VNNAG+ + K E + ++ +VN LGA+RV A
Sbjct: 91 EFLK---SQLKNR---SLDILVNNAGIGGHSTSKLEDLDIERLKHTFNVNSLGALRVTQA 144
Query: 484 FLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKS 612
+P ++ + + + R+ ++ + G Y ASKS
Sbjct: 145 LIPNMKMGSRKIVANMSSRMGSIQQNAG-----GAIGYRASKS 182
>UniRef50_A3LZX3 Cluster: 1-acyl dihydroxyacetone phosphate
reductase; n=6; Saccharomycetales|Rep: 1-acyl
dihydroxyacetone phosphate reductase - Pichia stipitis
(Yeast)
Length = 297
Score = 53.2 bits (122), Expect = 5e-06
Identities = 42/163 (25%), Positives = 73/163 (44%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVES 303
++ +TG SG+G+A + A+ G+ AG + E + L + TF LDV+ +ES
Sbjct: 10 KVALITGASSGIGYATSIEFAKRGYKVFAGARR---LEPMEPLREHGVITFKLDVSSLES 66
Query: 304 VQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISA 483
V+ +++++ D + + NNAG +T + VN+ G MR+
Sbjct: 67 VKSAKQFIIEQTGD---HYLDVLFNNAGQSCTFPAIDVTDEWFKQCFEVNVFGPMRLTRE 123
Query: 484 FLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKS 612
P + K I GS G+ P P + YS++K+
Sbjct: 124 LSPLL--------INAKGAIGFTGSVSGVIPFPFSSTYSSTKA 158
>UniRef50_Q82Q22 Cluster: Putative dehydrogenase; n=4;
Streptomyces|Rep: Putative dehydrogenase - Streptomyces
avermitilis
Length = 307
Score = 52.8 bits (121), Expect = 7e-06
Identities = 44/164 (26%), Positives = 73/164 (44%), Gaps = 1/164 (0%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREGF-ITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVE 300
R+ VTG G+G A+A RL+ G + + G + AA +L + DVT
Sbjct: 21 RVAVVTGAARGVGEALAQRLSAAGMLVALLGREEETLRRAAASLPNRNIYV-EADVTDHA 79
Query: 301 SVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVIS 480
++++ ++V DN VV NAG+ G + A + + + VNL+G+
Sbjct: 80 ALEDAARHV-----DNELGPASVVVANAGIAAGGPFTRTAADLWQRVIDVNLVGSANTAR 134
Query: 481 AFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKS 612
AFLP++ T + + + S P +AY ASK+
Sbjct: 135 AFLPQLTHT--------RGYFLQIASTAAFGSAPMMSAYCASKA 170
>UniRef50_Q6D7W8 Cluster: Probable short chain dehydrogenase; n=1;
Pectobacterium atrosepticum|Rep: Probable short chain
dehydrogenase - Erwinia carotovora subsp. atroseptica
(Pectobacterium atrosepticum)
Length = 256
Score = 52.8 bits (121), Expect = 7e-06
Identities = 42/171 (24%), Positives = 82/171 (47%), Gaps = 5/171 (2%)
Frame = +1
Query: 115 SVSRLVAVTGCDSGLGWAVAARLAREG-FITIAGMHKGIETEAAKALEKLCAHTFPLDVT 291
+ + + +TG SG+G +A R G + + G + E + + H F LD+
Sbjct: 3 TANNTILITGGGSGIGRELAQRFNDLGNTVIVTGRRASLLQETIAGRQNM--HAFELDID 60
Query: 292 RVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASM----IESPVHVNLL 459
+++ F + ++T + P + ++NNAG+M +YE ++ ++ + N+L
Sbjct: 61 DPKAINAFAQRIVT---EYPS--LNVLINNAGIM---RYEDLSTRSDLCDAQAQITTNVL 112
Query: 460 GAMRVISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKS 612
G +R+ +AF+ ++ S+ P I+NV S P A YSA+K+
Sbjct: 113 GPIRLTNAFIDHLK-------SQQNPAIVNVSSGLAFVPRADAAVYSATKA 156
>UniRef50_Q3KCP9 Cluster: Short-chain dehydrogenase/reductase SDR
precursor; n=7; Proteobacteria|Rep: Short-chain
dehydrogenase/reductase SDR precursor - Pseudomonas
fluorescens (strain PfO-1)
Length = 254
Score = 52.8 bits (121), Expect = 7e-06
Identities = 48/167 (28%), Positives = 84/167 (50%), Gaps = 6/167 (3%)
Frame = +1
Query: 130 VAVTGCDSGLGWAVAARLAREGF-ITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESV 306
+ +TG SG+G A+A + G + IAG + + E A+A + T LD+ + +
Sbjct: 8 IFITGGTSGIGRALAEAFHQRGNQVIIAGRRQALLDEIARANPGI--DTVQLDINDPQQI 65
Query: 307 QEFRKYVLTVLKDNPKYKFHAVVNNAGVMTV-----GKYEWMTASMIESPVHVNLLGAMR 471
++ + V++ +P + ++NNAG+M G Y+ A + + NLLG +R
Sbjct: 66 KDVAQ---EVIRRHPS--LNVIINNAGIMPFDNPASGDYDDEQAVSL---LQTNLLGPVR 117
Query: 472 VISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKS 612
V +AF+ +++ +P+ IIN S PL A A YSA+K+
Sbjct: 118 VSAAFVEHLKR-------QPEAFIINNSSVLAYLPLAATALYSATKA 157
>UniRef50_Q390V2 Cluster: Short-chain dehydrogenase/reductase SDR;
n=11; Proteobacteria|Rep: Short-chain
dehydrogenase/reductase SDR - Burkholderia sp. (strain
383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086
/ R18194))
Length = 273
Score = 52.8 bits (121), Expect = 7e-06
Identities = 49/172 (28%), Positives = 81/172 (47%), Gaps = 4/172 (2%)
Frame = +1
Query: 109 AMSVSRLVA-VTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLD 285
A + R VA VTG SG+G A+A RLA +G+ I + A A E A+
Sbjct: 27 ASRLHRPVALVTGSTSGIGAAIARRLAADGYAVILHSRSSADVGRAMARELGAAYVQADL 86
Query: 286 VTRVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIE--SPVH-VNL 456
E V+ R+ V + +VNNAGV V ++ + A+ E +H +N+
Sbjct: 87 ADDAERVRLIREAVAV------HGRLDVLVNNAGVSRVIPHDDLAAATPEVWREMHEINV 140
Query: 457 LGAMRVISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKS 612
+ R+++ +R+ A + ++NV SH G++P A Y+A+K+
Sbjct: 141 IAPFRLVAEAEAALREAASHGRA---GCVVNVSSHAGVRPKGASIPYAAAKA 189
>UniRef50_Q02B17 Cluster: Short-chain dehydrogenase/reductase SDR
precursor; n=1; Solibacter usitatus Ellin6076|Rep:
Short-chain dehydrogenase/reductase SDR precursor -
Solibacter usitatus (strain Ellin6076)
Length = 289
Score = 52.8 bits (121), Expect = 7e-06
Identities = 52/165 (31%), Positives = 72/165 (43%), Gaps = 4/165 (2%)
Frame = +1
Query: 127 LVAVTGCDSGLGWAVAARLAREGFITIAGMH---KGI-ETEAAKALEKLCAHTFPLDVTR 294
+ VTG +G+G A A LAR G A M +G E + E L PLDV
Sbjct: 3 IALVTGTSTGIGQATAVTLARGGHTVYATMRNPARGAGEIQEIAEKENLPVTVIPLDVDD 62
Query: 295 VESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRV 474
SV + V VL + + +VNNAG+ G E + + + + N GA+R
Sbjct: 63 DASV---KAGVAQVLAQSGRVD--VLVNNAGIGMHGSVEELPVADFKRAMETNFFGALRC 117
Query: 475 ISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
I A LP +R+ + I+NV S G A Y+ASK
Sbjct: 118 IQAVLPGMRE-------RRHGVIVNVSSVAGRFSSAPQAPYAASK 155
>UniRef50_A7IE62 Cluster: Short-chain dehydrogenase/reductase SDR;
n=2; Alphaproteobacteria|Rep: Short-chain
dehydrogenase/reductase SDR - Xanthobacter sp. (strain
Py2)
Length = 242
Score = 52.8 bits (121), Expect = 7e-06
Identities = 44/154 (28%), Positives = 72/154 (46%), Gaps = 5/154 (3%)
Frame = +1
Query: 112 MSVSRLVA-VTGCDSGLGWAVAARLA-REGFITIAG---MHKGIETEAAKALEKLCAHTF 276
M + ++A V+G + G+G A+AA LA R+G + G + +G E L
Sbjct: 1 METNEIIALVSGANRGIGLAIAAGLARRKGVNVLLGCRDLDRGKTASLPLLAEGLRVRPV 60
Query: 277 PLDVTRVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNL 456
LD T SV ++ +N + A+VNNAG+ I+ + VN+
Sbjct: 61 QLDATDEASVSSLAHFI-----ENEYGRLDALVNNAGIGLDYDPSLSVVERIQKTLDVNV 115
Query: 457 LGAMRVISAFLPEIRKTAIETTSKPKPRIINVGS 558
+GA+R+ A +P + K+ +PRI+NV S
Sbjct: 116 VGALRLTEAMVPLLAKST-------RPRIVNVSS 142
>UniRef50_A7H6A6 Cluster: Short-chain dehydrogenase/reductase SDR;
n=2; Anaeromyxobacter|Rep: Short-chain
dehydrogenase/reductase SDR - Anaeromyxobacter sp.
Fw109-5
Length = 342
Score = 52.8 bits (121), Expect = 7e-06
Identities = 51/165 (30%), Positives = 68/165 (41%), Gaps = 3/165 (1%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAK---ALEKLCAHTFPLDVTR 294
++ VTG GLG VA L R G + E E A+ A E + P DVT
Sbjct: 33 KIALVTGGSRGLGLLVARELGRRGMRVVVLARDEEELERARSSLAAEGIDVTALPCDVTD 92
Query: 295 VESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRV 474
E +Q V L P +VNNAG++ VG E M + V GA+
Sbjct: 93 EEGIQGLVADVEQNL--GP---IDVLVNNAGIIQVGPVETMKPDDYRRAMDVMFWGALNA 147
Query: 475 ISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
A LP +R+ + + I+NV S LP A Y A+K
Sbjct: 148 AEAVLPGMRQ-------RRRGTIVNVTSIGAAVGLPHLAPYDAAK 185
>UniRef50_A4XF79 Cluster: Short-chain dehydrogenase/reductase SDR
precursor; n=1; Novosphingobium aromaticivorans DSM
12444|Rep: Short-chain dehydrogenase/reductase SDR
precursor - Novosphingobium aromaticivorans (strain DSM
12444)
Length = 327
Score = 52.8 bits (121), Expect = 7e-06
Identities = 46/163 (28%), Positives = 73/163 (44%), Gaps = 5/163 (3%)
Frame = +1
Query: 136 VTGCDSGLGWAVAARLAREGFITIAGMHK----GIETEAAKALEKLCAHT-FPLDVTRVE 300
+TG +G G VA +A G+ A M G E +LE A +DVT
Sbjct: 7 LTGGSTGFGAGVALEMAARGWTVFASMRDLAKAGRLMEYTASLESGGAIVPVRIDVTDGA 66
Query: 301 SVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVIS 480
S++ VL + + + A++NNAG + +E MT + + + + N GA+ +
Sbjct: 67 SIESGLAEVL----ERTEGRLDALLNNAGYSVIAPFEEMTEADVRAQMETNFFGALAITR 122
Query: 481 AFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
A LP +R + RI+ V S+ P P + Y+ASK
Sbjct: 123 AVLPTMRDAG-------RGRILTVTSNAVNTPHPMLSLYAASK 158
>UniRef50_Q872E5 Cluster: Putative uncharacterized protein
80A10.300; n=1; Neurospora crassa|Rep: Putative
uncharacterized protein 80A10.300 - Neurospora crassa
Length = 296
Score = 52.8 bits (121), Expect = 7e-06
Identities = 46/166 (27%), Positives = 71/166 (42%)
Frame = +1
Query: 115 SVSRLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTR 294
S R+ +TG SGLG +A R +G I A + + ++LC LDVT
Sbjct: 3 STPRVWLITGASSGLGREIALRALAQGDIVFATARNPAKIPESLTSQELCIPE-TLDVTS 61
Query: 295 VESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRV 474
++V + N + VVN+AG + G E +A + + N+LG + V
Sbjct: 62 PDAVLAETVARIVSHPKNVSGRIDIVVNSAGYVLAGGCEEASAEEAFAQFNTNVLGQLAV 121
Query: 475 ISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKS 612
A LP +R+ T + NVGS P YS++K+
Sbjct: 122 GRAVLPVLRRQRAGT-------LANVGSILSYLGPPGGGLYSSTKA 160
>UniRef50_Q8R9W0 Cluster: Dehydrogenases with different
specificities; n=4; Bacteria|Rep: Dehydrogenases with
different specificities - Thermoanaerobacter
tengcongensis
Length = 247
Score = 52.4 bits (120), Expect = 9e-06
Identities = 52/170 (30%), Positives = 76/170 (44%), Gaps = 2/170 (1%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTR--V 297
R+ VTG G+G A+A RLA++GF IA + + A + +E++ H + V
Sbjct: 6 RVAFVTGGSRGIGRAIAVRLAKDGF-NIAITYVKDDKSAEEVVEEVKKHGVDALAIKCDV 64
Query: 298 ESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVI 477
E K V V+++ VVNNAG+ M + + VNL GA VI
Sbjct: 65 SKYHEVEKAVEKVIEEFG--SIDVVVNNAGITKDNLILKMEEEEWDQVIDVNLKGAFNVI 122
Query: 478 SAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKSWPFGV 627
+ K K K +IIN+ S GL A Y+ASK+ G+
Sbjct: 123 KFASKYMIK-------KRKGKIINISSVVGLMGNVGQANYAASKAGIIGL 165
>UniRef50_Q8EQ60 Cluster: Oxidoreductase; n=1; Oceanobacillus
iheyensis|Rep: Oxidoreductase - Oceanobacillus iheyensis
Length = 267
Score = 52.4 bits (120), Expect = 9e-06
Identities = 40/173 (23%), Positives = 82/173 (47%), Gaps = 4/173 (2%)
Frame = +1
Query: 118 VSRLVAVTGCDSGLGWAVAARLARE-GFITIAGMHKGIETEAAKALEKLC---AHTFPLD 285
V++ + +TG SG+G +A ++A + GF + + K +++L + +P+D
Sbjct: 8 VNKKIIITGASSGIGEMLAKKVASQGGFPILVARSRDKLITIQKEIDQLYNQRSAIYPID 67
Query: 286 VTRVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGA 465
+T +++ + ++ DN + A++NNAG+ E M + +N+
Sbjct: 68 LTDKDNIDNL---IPAIINDNK--QIDALINNAGLGVFDSIEDMNYDDLLETFQLNVFAG 122
Query: 466 MRVISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKSWPFG 624
+++ + +P +RKT T +I+NV S P A+Y++SK G
Sbjct: 123 IQLSQSIIPYLRKTNANT------QIVNVISQAAKISTPKSASYASSKQAMLG 169
>UniRef50_Q5NM60 Cluster: Short-chain alcohol dehydrogenase; n=14;
cellular organisms|Rep: Short-chain alcohol
dehydrogenase - Zymomonas mobilis
Length = 248
Score = 52.4 bits (120), Expect = 9e-06
Identities = 53/166 (31%), Positives = 77/166 (46%), Gaps = 3/166 (1%)
Frame = +1
Query: 121 SRLVAVTGCDSGLGWAVAARLAREGFITIAGMHKG--IETEAAKALEKLC-AHTFPLDVT 291
+++V +TG SGLG A L+ G + G + I T A + K A DVT
Sbjct: 7 NKIVVITGASSGLGAETARHLSDLGATVVLGARREERIATLANSIVAKGGQALAIKTDVT 66
Query: 292 RVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMR 471
ESV+ V T +K + ++NNAGVM + E + E V VN+ G +
Sbjct: 67 DRESVKNL---VDTAVKTYGRVD--VLLNNAGVMPLSPLEKLRVDEWELMVDVNIKGVLY 121
Query: 472 VISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
I+A LP ++ S+ IINV S G + + A YSA+K
Sbjct: 122 GIAAALPHMK-------SQKFGHIINVSSVAGHKVIDGGAVYSATK 160
>UniRef50_Q5KZB7 Cluster: 3-oxoacyl-[acyl-carrier protein]
reductase; n=2; Geobacillus|Rep: 3-oxoacyl-[acyl-carrier
protein] reductase - Geobacillus kaustophilus
Length = 256
Score = 52.4 bits (120), Expect = 9e-06
Identities = 49/167 (29%), Positives = 71/167 (42%), Gaps = 5/167 (2%)
Frame = +1
Query: 127 LVAVTGCDSGLGWAVAARLAREG-FITIAGMHKGIETEAAKALEKL----CAHTFPLDVT 291
+ +TG SG+G A A RLA+EG + + G E + + +L A F DVT
Sbjct: 7 VAVITGGGSGIGRATAVRLAQEGATVVLVGRTAVKLEETVQDITRLGVPGVADRFAADVT 66
Query: 292 RVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMR 471
E V+ YV N H +VNNAG+ T K+ +T + VN+
Sbjct: 67 DHEQVRALAAYV-----QNRYGDLHVLVNNAGISTHTKWLELTEQEWDDVQRVNMKSVFL 121
Query: 472 VISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKS 612
V P + + A + I+NV S G Q YSA+K+
Sbjct: 122 VSQTLAPLMIEGA--KRERANRAIVNVASLSGHQAGAEIPHYSAAKA 166
>UniRef50_Q2S401 Cluster: Oxidoreductase, short chain
dehydrogenase/reductase family; n=1; Salinibacter ruber
DSM 13855|Rep: Oxidoreductase, short chain
dehydrogenase/reductase family - Salinibacter ruber
(strain DSM 13855)
Length = 267
Score = 52.4 bits (120), Expect = 9e-06
Identities = 50/168 (29%), Positives = 66/168 (39%), Gaps = 4/168 (2%)
Frame = +1
Query: 121 SRLVAVTGCDSGLGWAVAARLAREGFITIAGMHKG--IETEAAKALEKLCAHTFPL--DV 288
+R V G GLG A A LAREG G I T A + A PL DV
Sbjct: 7 NRTAFVAGASKGLGRATAHELAREGCSVALCSRDGDRIRTAAKAIRDDTGAEVLPLVCDV 66
Query: 289 TRVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAM 468
T E V+ N H +V NAG G + S V +NL+ +
Sbjct: 67 TDAEQVES-----AIAQTANTFGGLHVLVTNAGGPPSGAATELDPSDYRDAVELNLMSTI 121
Query: 469 RVISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKS 612
+ A LP +R A E R+I V S QP+P A + +++
Sbjct: 122 SLCDAALPHLRMAAAE---DDHARVIMVTSVSSKQPIPTLALSNTARA 166
>UniRef50_Q1N298 Cluster: Short chain dehydrogenase; n=1;
Oceanobacter sp. RED65|Rep: Short chain dehydrogenase -
Oceanobacter sp. RED65
Length = 265
Score = 52.4 bits (120), Expect = 9e-06
Identities = 46/165 (27%), Positives = 77/165 (46%), Gaps = 1/165 (0%)
Frame = +1
Query: 121 SRLVAVTGCDSGLGWAVAARLAREGF-ITIAGMHKGIETEAAKALEKLCAHTFPLDVTRV 297
S++V +TG SGLG ++ ++G + + + + AK L + A + LD+T
Sbjct: 6 SKIVLITGAASGLGLEMSKVFIKKGHQVIMVDLQIDKLKQEAKELG-VNAFAYELDLTNG 64
Query: 298 ESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVI 477
+SV + + K +VNNAG+ E +IE + V+ LG +R+
Sbjct: 65 DSVSQLVDDITKQFKT-----LDVLVNNAGITHRSLAEQTDIKVIEKVMAVDYLGPVRLA 119
Query: 478 SAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKS 612
+ LP + S+ K +IN+GS G P+ A Y A+KS
Sbjct: 120 QSCLPLL--------SESKGDVINIGSMAGWMPVLGRAGYCAAKS 156
>UniRef50_Q1DCG1 Cluster: Oxidoreductase, short-chain
dehydrogenase/reductase family; n=4; Bacteria|Rep:
Oxidoreductase, short-chain dehydrogenase/reductase
family - Myxococcus xanthus (strain DK 1622)
Length = 348
Score = 52.4 bits (120), Expect = 9e-06
Identities = 43/161 (26%), Positives = 74/161 (45%), Gaps = 1/161 (0%)
Frame = +1
Query: 130 VAVTGCDSGLGWAVAARLARE-GFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESV 306
V +TG GLG +A +L +E + I G + A + LE+ + + + V
Sbjct: 44 VLITGGSRGLGLVLARQLLKEEARVAICGRDEQTLERAREELERTGGEVYAIPCDVRDPV 103
Query: 307 QEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAF 486
Q + +++ + + ++NNAGV+ VG E MT + + +L + A
Sbjct: 104 QV--EAMVSAIHERWG-TVDVLINNAGVIQVGPLESMTLEDFQEAIDTHLWAPLYTTLAV 160
Query: 487 LPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
LPE+++ + K RI+N+ S G +P YSASK
Sbjct: 161 LPEMKR-------RGKGRIVNIASVGGKVSIPHLVPYSASK 194
>UniRef50_A3ZTM1 Cluster: Probable short-chain dehydrogenase; n=1;
Blastopirellula marina DSM 3645|Rep: Probable
short-chain dehydrogenase - Blastopirellula marina DSM
3645
Length = 299
Score = 52.4 bits (120), Expect = 9e-06
Identities = 44/165 (26%), Positives = 73/165 (44%), Gaps = 3/165 (1%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIE-TEAAKALEKLCAHTFPL--DVTR 294
++ VTG GLG A+A RL R+G I + AA++L+ L P+ DVT
Sbjct: 33 KVALVTGASRGLGLAIARRLVRQGATVILTARDPADLAAAAESLKGLSGAAIPMAADVTS 92
Query: 295 VESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRV 474
+ V+ K + ++ + +VNN G+ + GK + +N++ A+R
Sbjct: 93 DDDVKRLEKEI-----ESRFGRLDLLVNNVGISSRGKLLETQLADFRRQWELNVMTAIRC 147
Query: 475 ISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
+ AF P I +K K I+N+GS Y+ +K
Sbjct: 148 VQAFAPMI--------TKRKGHIVNIGSLASKSAARFIGPYATTK 184
>UniRef50_A3JFT9 Cluster: Short chain dehydrogenase; n=1;
Marinobacter sp. ELB17|Rep: Short chain dehydrogenase -
Marinobacter sp. ELB17
Length = 273
Score = 52.4 bits (120), Expect = 9e-06
Identities = 53/176 (30%), Positives = 80/176 (45%), Gaps = 6/176 (3%)
Frame = +1
Query: 130 VAVTGCDSGLGWAVAARLAREGFITIAG---MHKG--IETEAAKALEKLCAHTFPLDVTR 294
V +TG SGLG A+A R AREG G +G +E E +KA + + DV R
Sbjct: 5 VFITGGASGLGRAIALRYAREGAKVCIGDVNPQQGALVEQEISKAGGE--GYYVDCDVRR 62
Query: 295 VESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRV 474
++ ++ R + VVNNAGV + G E + E + +N+LG +R
Sbjct: 63 LKDLERVRDDLAARWGG-----VDIVVNNAGVASAGSIEDTPMADWEWILDINVLGVVRG 117
Query: 475 ISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKSWPFGV-DTMS 639
AF P ++ T +N+ S GL P +Y+ SK+ + +TMS
Sbjct: 118 CKAFTPMFKQQGAGT-------FVNIASMAGLMLAPMMNSYNVSKAGVIALSETMS 166
>UniRef50_A2SJ81 Cluster: Oxidoreductase, short-chain
dehydrogenase/reductase family; n=1; Methylibium
petroleiphilum PM1|Rep: Oxidoreductase, short-chain
dehydrogenase/reductase family - Methylibium
petroleiphilum (strain PM1)
Length = 265
Score = 52.4 bits (120), Expect = 9e-06
Identities = 47/166 (28%), Positives = 73/166 (43%), Gaps = 6/166 (3%)
Frame = +1
Query: 130 VAVTGCDSGLGWAVAARLAREGF-ITIAGMHKGIETEAAKALEK-----LCAHTFPLDVT 291
V +TG G+G AVA L+ G + + G G A+ LE D+T
Sbjct: 10 VVLTGASGGIGAAVARALSGAGARLLLVGRDAGRLAALARTLETHPDQPRRVEVLAADLT 69
Query: 292 RVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMR 471
V+ R+ L + + +VNNAGV + G+ + + + I V NL+ M
Sbjct: 70 TSAGVEAVRRVALA-------RRANVLVNNAGVASFGRLDALDDAHILQAVTTNLVAPML 122
Query: 472 VISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
+ A LP + ++ ++NVGS G LP F+ YSA+K
Sbjct: 123 LTRALLPGL-------LAQRSAAVLNVGSVLGRLALPGFSVYSATK 161
>UniRef50_A1G528 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Salinispora arenicola CNS205|Rep: Short-chain
dehydrogenase/reductase SDR - Salinispora arenicola
CNS205
Length = 237
Score = 52.4 bits (120), Expect = 9e-06
Identities = 47/145 (32%), Positives = 65/145 (44%), Gaps = 1/145 (0%)
Frame = +1
Query: 136 VTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESVQEF 315
VTG + G+G RL G+ G +A A E + AH LDVT SV+
Sbjct: 13 VTGANKGIGLETVRRLVEAGYRVYLGARSKERGQA--AAEAVGAHFLELDVTCDASVRPA 70
Query: 316 RKYVLTVLKDNPKYKFHAVVNNAGVM-TVGKYEWMTASMIESPVHVNLLGAMRVISAFLP 492
+V + +VNNAG+ V TA I + N++G +R+I AFLP
Sbjct: 71 VAFV-----EQADGHLDVLVNNAGITGPVRDPHDYTADDITEVLLTNVVGYVRLIHAFLP 125
Query: 493 EIRKTAIETTSKPKPRIINVGSHCG 567
+ K+ PRI+NVGS G
Sbjct: 126 LLEKS-------DAPRIVNVGSGLG 143
>UniRef50_A0Z215 Cluster: Short chain dehydrogenase; n=2;
Gammaproteobacteria|Rep: Short chain dehydrogenase -
marine gamma proteobacterium HTCC2080
Length = 291
Score = 52.4 bits (120), Expect = 9e-06
Identities = 44/162 (27%), Positives = 78/162 (48%), Gaps = 1/162 (0%)
Frame = +1
Query: 130 VAVTGCDSGLGWAVAARLAREGF-ITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESV 306
+ +TG SGLG A+A + A EG+ + IA + + A L + A+ + S
Sbjct: 4 ILITGAASGLGLALAKKYASEGWSVCIADIQDEEGIKIAAQLNEEYANDCFFQHLNITSD 63
Query: 307 QEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAF 486
++++ L L A+VNNAGV G + + + V +NL+GA++
Sbjct: 64 TQWQE--LVALISERWQGLDALVNNAGVGASGDIDTFSIKDFQWTVDINLMGAVKGCHVC 121
Query: 487 LPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKS 612
+P ++++ K +INV S GL + + +AY+ SK+
Sbjct: 122 VPLLKES--------KGLLINVASMAGLLHMGSMSAYNVSKA 155
>UniRef50_A0M1K4 Cluster: Short-chain dehydrogenase/reductase family
protein; n=4; cellular organisms|Rep: Short-chain
dehydrogenase/reductase family protein - Gramella
forsetii (strain KT0803)
Length = 249
Score = 52.4 bits (120), Expect = 9e-06
Identities = 49/170 (28%), Positives = 80/170 (47%), Gaps = 7/170 (4%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREGF-ITIAGMHKGIETEAAKALEKL---CAHTFPLDVT 291
+ + +TG SG+G A A RLA+EG + + + E ++K A P DVT
Sbjct: 6 KTIIITGASSGIGEATAMRLAKEGVNVVLTARREEKLKELKSKIDKENGGKALVIPGDVT 65
Query: 292 RVESVQEFRKYVLTVLKDNPKYKFHAV---VNNAGVMTVGKYEWMTASMIESPVHVNLLG 462
+ E +F+ + D K +F ++ +NNAG+M + + + + V VN+ G
Sbjct: 66 KKE---DFKNLI-----DKTKKEFGSIDGLINNAGLMPLSYVKNLHTDEWDKMVDVNIKG 117
Query: 463 AMRVISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKS 612
+ ++A LP T +E S IIN+ S + P A Y A+KS
Sbjct: 118 VLNGVAAVLP----TMMEQKS---GNIINISSSAARKIYPGGAVYCATKS 160
>UniRef50_Q7XZ53 Cluster: Short-chain alcohol dehydrogenase family
enzyme; n=1; Griffithsia japonica|Rep: Short-chain
alcohol dehydrogenase family enzyme - Griffithsia
japonica (Red alga)
Length = 210
Score = 52.4 bits (120), Expect = 9e-06
Identities = 51/167 (30%), Positives = 71/167 (42%), Gaps = 1/167 (0%)
Frame = +1
Query: 112 MSVSRLVAVTGCDSGLGWAVAARLA-REGFITIAGMHKGIETEAAKALEKLCAHTFPLDV 288
M+ V +TGC SG+G A+A LA + G+ IA + K + A+ LDV
Sbjct: 1 MTSKHTVVITGCSSGIGIALALLLADKPGYTVIATLRKPSKAPASLT-SHASIDVQRLDV 59
Query: 289 TRVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAM 468
T ES +YV L+ VVNNAG G E + VN+ G
Sbjct: 60 TDDESTDALARYVK--LQHGGA---SIVVNNAGFGIPGSLEQVGLEDAAGIFAVNVWGVA 114
Query: 469 RVISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
RV AF P +R ++ ++ V S G +P Y+ASK
Sbjct: 115 RVTRAFAPHLR-------ARGGGLVVTVSSTSGWLAVPYLDYYTASK 154
>UniRef50_Q7SHI2 Cluster: Putative uncharacterized protein
NCU02922.1; n=2; Sordariomycetes|Rep: Putative
uncharacterized protein NCU02922.1 - Neurospora crassa
Length = 290
Score = 52.4 bits (120), Expect = 9e-06
Identities = 47/165 (28%), Positives = 78/165 (47%), Gaps = 1/165 (0%)
Frame = +1
Query: 121 SRLVAVTGCDSG-LGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRV 297
++ +TGC +G +G A+ R G IA + + E+++ L+K F LDVT
Sbjct: 6 TKFALITGCGAGGIGEALILEYLRRGIHPIATL---LPFESSEHLDKAGITWFKLDVTNE 62
Query: 298 ESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVI 477
ESV + +K V + K + +VNNAG+ ++ VNL G MR++
Sbjct: 63 ESVVQLKKDVSELTKG----RLDFLVNNAGICYTMTAIDTDVKSVQRMFDVNLFGPMRMV 118
Query: 478 SAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKS 612
F I ++ I+N+GS G+ P ++Y+ASK+
Sbjct: 119 HHF----HDMLIASSG----IIVNIGSIGGVVPFVYGSSYNASKA 155
>UniRef50_Q5KC11 Cluster: Ketoreductase, putative; n=1;
Filobasidiella neoformans|Rep: Ketoreductase, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 361
Score = 52.4 bits (120), Expect = 9e-06
Identities = 48/166 (28%), Positives = 76/166 (45%), Gaps = 7/166 (4%)
Frame = +1
Query: 136 VTGCDSGLGWAVAARLAREGF-ITIAGMHKGIETEAAKALE-KLCAHT--FPLDVTRVES 303
VTGC SG+G A +LA + F I + G + T+ +K +E K HT +DV+ S
Sbjct: 80 VTGCTSGIGLEFARQLAAKKFNIILVGRRQSALTDLSKEIESKYDVHTKSVTVDVSTPGS 139
Query: 304 VQEFRKYVLTVLKDNPKYKFHAVVNNAGV---MTVGKYEWMTASMIESPVHVNLLGAMRV 474
++ L +L N ++NN G M V +E + M + N+ V
Sbjct: 140 ARDDALTQLELLAQN--LDVGILINNVGASHSMPVAFHETERSEMSRI-IETNVTWTYLV 196
Query: 475 ISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKS 612
+ LP + + + PK +I +GS G P P A+YS +K+
Sbjct: 197 TRSILPSMVARS-KQKGAPKSLVITIGSLSGRIPSPLLASYSGTKA 241
>UniRef50_UPI000038DA04 Cluster: COG1028: Dehydrogenases with
different specificities (related to short-chain alcohol
dehydrogenases); n=1; Nostoc punctiforme PCC 73102|Rep:
COG1028: Dehydrogenases with different specificities
(related to short-chain alcohol dehydrogenases) - Nostoc
punctiforme PCC 73102
Length = 267
Score = 52.0 bits (119), Expect = 1e-05
Identities = 51/166 (30%), Positives = 73/166 (43%)
Frame = +1
Query: 112 MSVSRLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVT 291
M+ ++V VTG SG G A +LA G+ K A+ +E L LDVT
Sbjct: 1 MTDKKVVLVTGASSGFGQLTAKKLAAVGYWVFGTSRKSY--PASGDVEML-----KLDVT 53
Query: 292 RVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMR 471
SVQ K +LT + N + ++NNAG + E + + N G +R
Sbjct: 54 SDSSVQLCIKQLLT--RTN---RIDLLINNAGQIHASMLEETSLQQAKEIFETNFWGVVR 108
Query: 472 VISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
+ +A LP +R+ + IIN+ S GL P YSASK
Sbjct: 109 LTNAVLPVMRQ-------QRSGHIINISSVAGLIGAPGQGFYSASK 147
>UniRef50_Q1LWF3 Cluster: Novel protein; n=9; Euteleostomi|Rep:
Novel protein - Danio rerio (Zebrafish) (Brachydanio
rerio)
Length = 256
Score = 52.0 bits (119), Expect = 1e-05
Identities = 40/163 (24%), Positives = 70/163 (42%), Gaps = 7/163 (4%)
Frame = +1
Query: 100 IVSAMSVSRLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCA---- 267
+++A + +TG GLG + L GF + AK L++L
Sbjct: 1 MINAFQNCSNLMITGASRGLGLQIVESLVTGGFSPGKIIATARNPNGAKELQRLAEEYQN 60
Query: 268 -HTFPLDVTRVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPV 444
H LDV ES++ V ++++ + ++NNAG+ V E +TA +
Sbjct: 61 IHIIKLDVISQESIERAAAEVEELVQEEG---LNCLINNAGINVVANLETVTADQMLENF 117
Query: 445 HVNLLGAMRVISAFLPEIRKTAIETTSK--PKPRIINVGSHCG 567
H N + + + A LP +++ A + T + +INV S G
Sbjct: 118 HTNSVAPLMITKAMLPLLKRAAAKGTGMGIHRAAVINVTSLLG 160
>UniRef50_Q46241 Cluster: NanH gene & ORF1,2,3 & 4 precursor; n=4;
Clostridium perfringens|Rep: NanH gene & ORF1,2,3 & 4
precursor - Clostridium perfringens
Length = 190
Score = 52.0 bits (119), Expect = 1e-05
Identities = 45/162 (27%), Positives = 71/162 (43%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVES 303
+++ +TG SG+G++ A L EG I + E + L++L LDV +
Sbjct: 4 KVILITGASSGIGYSTAKLLLEEGHIVYCTARR---VENMRELQRLGGKIIFLDVKDERA 60
Query: 304 VQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISA 483
VQ K V T+++ + + V N+ G E + + VNL G RVI A
Sbjct: 61 VQ---KVVNTIIR--MESRIDVVFANSXYACAGALETVNIDDAKEEFDVNLFGVARVIKA 115
Query: 484 FLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
+P++RK + II S G+ P + Y ASK
Sbjct: 116 VMPQMRK-------QKYGYIIVTSSLVGIVSTPMMSFYPASK 150
>UniRef50_Q1ZIG4 Cluster: Putative short-chain dehydrogenase; n=1;
Psychromonas sp. CNPT3|Rep: Putative short-chain
dehydrogenase - Psychromonas sp. CNPT3
Length = 254
Score = 52.0 bits (119), Expect = 1e-05
Identities = 43/168 (25%), Positives = 80/168 (47%), Gaps = 2/168 (1%)
Frame = +1
Query: 118 VSRLVAVTGCDSGLGWAVAARLAREG--FITIAGMHKGIETEAAKALEKLCAHTFPLDVT 291
+ ++V +TG SGLG A +LA +G + IA +++ A + + K AH +
Sbjct: 1 MGKVVVITGASSGLGEEFAYQLAEQGASLLLIARRSSKLQSIAQQIMTKY-AHVKVYVLV 59
Query: 292 RVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMR 471
SV + ++VL ++ + + ++NNAG G +E + ++ + + VN+ M
Sbjct: 60 LDLSVDDASEHVLNYIETH-QLSLQGLINNAGFGARGYFESLELTLQQQMLQVNIHILMS 118
Query: 472 VISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKSW 615
+ + +++ S+ IINV S Q P A Y ASK++
Sbjct: 119 LTHCLIAQLK-------SQENAFIINVASTAAFQAGPNLAVYYASKAF 159
>UniRef50_Q02BL8 Cluster: Short-chain dehydrogenase/reductase SDR
precursor; n=1; Solibacter usitatus Ellin6076|Rep:
Short-chain dehydrogenase/reductase SDR precursor -
Solibacter usitatus (strain Ellin6076)
Length = 257
Score = 52.0 bits (119), Expect = 1e-05
Identities = 43/164 (26%), Positives = 73/164 (44%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVES 303
R+ VTG SG+G A A RL+R+GF I + E+ A E A T D+T+ E
Sbjct: 4 RVAMVTGASSGIGAAFARRLSRDGFALILVARRADRLESL-ARELGGAETVAADLTQHEG 62
Query: 304 VQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISA 483
+ + + + +VNNAG T GK+ + ++ ++++ MR+ A
Sbjct: 63 LARVEQRIASAA------DLELLVNNAGFGTKGKFHETSLEGQDAMHRLHVIATMRLTRA 116
Query: 484 FLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKSW 615
L + + + +INV S P +Y ++K+W
Sbjct: 117 ALAAM-------VPRGRGGVINVSSVAAFGQSPGNVSYCSTKAW 153
>UniRef50_A5WY75 Cluster: Orf_Bo159; n=22; Bacteria|Rep: Orf_Bo159 -
Agrobacterium tumefaciens
Length = 262
Score = 52.0 bits (119), Expect = 1e-05
Identities = 47/172 (27%), Positives = 76/172 (44%), Gaps = 4/172 (2%)
Frame = +1
Query: 112 MSVSRLVAVTGCDSGLGWAVAARLAREG--FITIAGMHKGIETEAAKALEKLCAHT-FPL 282
M+ V +TG +G+G A R A+ G + +A +ET A E+L A T +
Sbjct: 1 MTAKPSVLITGASTGIGAGYAERFAQRGHDLVLVARNTSRMETLA----ERLRAETGVAI 56
Query: 283 DVTRVESVQEFRKYVLTV-LKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLL 459
D+ + + V+ L D+ + ++NNAG G + T IE V +N
Sbjct: 57 DIIAADLANSAERAVVEARLSDDARIGI--LINNAGTTLAGTFVEQTTDDIERLVTLNTT 114
Query: 460 GAMRVISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKSW 615
+R+ A P + + + IIN+GS GL P A Y A+K++
Sbjct: 115 ALVRLAHAIAPRLAQAG-------EGSIINIGSVVGLAPEFGMAVYGATKAF 159
>UniRef50_A4XEF9 Cluster: Short-chain dehydrogenase/reductase SDR;
n=1; Novosphingobium aromaticivorans DSM 12444|Rep:
Short-chain dehydrogenase/reductase SDR -
Novosphingobium aromaticivorans (strain DSM 12444)
Length = 245
Score = 52.0 bits (119), Expect = 1e-05
Identities = 51/165 (30%), Positives = 77/165 (46%), Gaps = 2/165 (1%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAREGF-ITIAGMH-KGIETEAAKALEKLCAHTFPLDVTRV 297
++ VTG SGLG A+A A EG + +A + G ET AA+ + A PLDVT+
Sbjct: 7 KVTFVTGGASGLGEAIARAFAAEGASVVVADIDVAGGETLAAQ----IGAQFVPLDVTQE 62
Query: 298 ESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVI 477
S E P + +VNNAG+ T+G E +T + +++LG I
Sbjct: 63 GSWAEAVA---------PFERIDVLVNNAGITTLGSVEEITLDQFRHELDIDVLGVFMGI 113
Query: 478 SAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKS 612
A LP ++ IIN+ S G++ AY+A+K+
Sbjct: 114 QATLPRMKTHG--------GSIINMSSLSGVKASANLVAYNAAKA 150
>UniRef50_A1UPA3 Cluster: Short-chain dehydrogenase/reductase SDR;
n=12; Actinomycetales|Rep: Short-chain
dehydrogenase/reductase SDR - Mycobacterium sp. (strain
KMS)
Length = 222
Score = 52.0 bits (119), Expect = 1e-05
Identities = 42/158 (26%), Positives = 74/158 (46%)
Frame = +1
Query: 136 VTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESVQEF 315
+TG GLG A+A LA + +AG E A ++L A T+ +D V+++
Sbjct: 6 ITGASRGLGAAIATALAPTHTLFLAGRPSAQLDEVA---QRLGATTWEIDFDDVDTIPAA 62
Query: 316 RKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAFLPE 495
+ P + +++NAGV + T + ++VN++GA+ + A LP
Sbjct: 63 VE---------PIVELDVLIHNAGVAYPARVAESTVDEWRATMNVNVIGAVALTLALLPA 113
Query: 496 IRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
+R + P +++ + S G+ P A+YSASK
Sbjct: 114 LR-------AAPDGQVVFINSGSGINASPGLASYSASK 144
>UniRef50_A1IB88 Cluster: Oxidoreductase, short chain
dehydrogenase/reductase family precursor; n=5;
Proteobacteria|Rep: Oxidoreductase, short chain
dehydrogenase/reductase family precursor - Candidatus
Desulfococcus oleovorans Hxd3
Length = 275
Score = 52.0 bits (119), Expect = 1e-05
Identities = 48/168 (28%), Positives = 78/168 (46%), Gaps = 3/168 (1%)
Frame = +1
Query: 118 VSRLVAVTGCDSGLGWAVAARLAREGF-ITIAGMHKGIETEAAKAL-EKLCAHTF-PLDV 288
+++ + +TG SGLG A+A + A G+ + I +++ A+ L E + F P DV
Sbjct: 1 MNQRIFITGGASGLGQALARQYAARGWRVCIGDVNQEAGEAFAQTLSEDIARAAFVPCDV 60
Query: 289 TRVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAM 468
TR +Q ++ + VVNNAGV G + S + + +NLLG +
Sbjct: 61 TRESDLQAAADWL-----EKNWGGVDIVVNNAGVAAAGGIAEVPLSDWQWILEINLLGVV 115
Query: 469 RVISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKS 612
R F P RK + R +N+ S GL P+ +Y+ SK+
Sbjct: 116 RGCKVFTPLFRK-------QGHGRFVNIASMAGLLNPPSSVSYNVSKA 156
>UniRef50_A0QN52 Cluster: DltE protein; n=1; Mycobacterium avium
104|Rep: DltE protein - Mycobacterium avium (strain 104)
Length = 254
Score = 52.0 bits (119), Expect = 1e-05
Identities = 48/161 (29%), Positives = 67/161 (41%)
Frame = +1
Query: 130 VAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPLDVTRVESVQ 309
V VTG +G+G +A R G I +G + A A T LD+ ++
Sbjct: 8 VLVTGGGTGIGRGLAEAFHRLGNRVIIAARRGEQLRAV-AEANPGIQTLSLDLGDPADIR 66
Query: 310 EFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISAFL 489
F V D + VVNNAG+ V A + E V VNLLG +R+I+ L
Sbjct: 67 RFATEVTDHYPD-----LNVVVNNAGMQRVEDLISGNAGLAEQTVAVNLLGPIRLIATLL 121
Query: 490 PEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKS 612
P + + +P I+NV S P Y ASK+
Sbjct: 122 PALLR-------RPHAAILNVTSGLAFMPSALTPTYCASKA 155
>UniRef50_A0PUC7 Cluster: Dehydrogenase/decarboxylase protein; n=1;
Mycobacterium ulcerans Agy99|Rep:
Dehydrogenase/decarboxylase protein - Mycobacterium
ulcerans (strain Agy99)
Length = 516
Score = 52.0 bits (119), Expect = 1e-05
Identities = 39/129 (30%), Positives = 60/129 (46%), Gaps = 2/129 (1%)
Frame = +1
Query: 130 VAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKLCAHTFPL--DVTRVES 303
+ VTG SG+G + A RLA G+ AG+ + + EA +A PL DVT E
Sbjct: 1 MVVTGASSGIGRSTALRLASAGWHVYAGVRRAADGEALQAASS-GGQLSPLLMDVTVAEQ 59
Query: 304 VQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISA 483
+ V V + +V+NAG+ E + + + VN++G + V A
Sbjct: 60 IDAA---VGIVGEHIGAAGLDGLVDNAGIGVASPVEMVPLDALRQQLQVNVVGQIAVTQA 116
Query: 484 FLPEIRKTA 510
FLP +R+ A
Sbjct: 117 FLPLLRRAA 125
>UniRef50_Q61YR4 Cluster: Putative uncharacterized protein CBG03429;
n=1; Caenorhabditis briggsae|Rep: Putative
uncharacterized protein CBG03429 - Caenorhabditis
briggsae
Length = 417
Score = 52.0 bits (119), Expect = 1e-05
Identities = 47/172 (27%), Positives = 80/172 (46%), Gaps = 13/172 (7%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAR-EGFITIAGMHKGIETEAAKALEKLCA-----HTFPLD 285
+ V +TG + G+G+ + L + G TI + +E AAK L+ H +D
Sbjct: 227 KTVFITGANRGIGFGIVRELLKVSGIETIIAGARNVE--AAKELQSFSQADSRLHLISVD 284
Query: 286 VTRVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKY-EWMTASMIESPVHVNLLG 462
V+ ES++ K V ++ D + ++NNAG++ + + + + + VN +G
Sbjct: 285 VSEDESLENSVKQVEGLVGDRG---LNLLINNAGILEHYRTTDPPNRATVLRTIDVNAVG 341
Query: 463 AMRVISAFLPEIRKTAIETT----SKPKPRIINVGSHCGLQPL--PAFAAYS 600
+ FLP ++K A T S K I+N+GS C Q L P F Y+
Sbjct: 342 PLMASQYFLPLLKKAAELTQGDELSVSKAAIVNIGSDCSSQTLNVPGFNEYT 393
Score = 46.0 bits (104), Expect = 8e-04
Identities = 42/163 (25%), Positives = 75/163 (46%), Gaps = 11/163 (6%)
Frame = +1
Query: 124 RLVAVTGCDSGLGWAVAARLAR-EGFITIAGMHKGIETEAAKALEKLCA-----HTFPLD 285
+ V + G + G+G + L + G TI + +ET AK L+ H +D
Sbjct: 4 KTVFIAGANRGIGLGIVKELLKVPGIETINAGARNVET--AKELQSFSQADSRLHLISVD 61
Query: 286 VTRVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKY-EWMTASMIESPVHVNLLG 462
V+ ES++ K V ++ D + ++NNAG++ + + + + + VN +
Sbjct: 62 VSEDESLENSVKQVEGLVGDRG---LNLLINNAGILEHYRTTDPPNRATVLRTIDVNAVS 118
Query: 463 AMRVISAFLPEIRKTAIETT----SKPKPRIINVGSHCGLQPL 579
A+ FLP ++K A +T S + I+N+GS C Q L
Sbjct: 119 ALLASQYFLPLLKKAAEQTQGDEFSVSRAGIVNIGSDCSSQTL 161
>UniRef50_Q9HSR4 Cluster: Oxidoreductase; n=6; cellular
organisms|Rep: Oxidoreductase - Halobacterium salinarium
(Halobacterium halobium)
Length = 260
Score = 52.0 bits (119), Expect = 1e-05
Identities = 51/172 (29%), Positives = 78/172 (45%), Gaps = 4/172 (2%)
Frame = +1
Query: 136 VTGCDSGLGWAVAARLAREGFITIAGMHKGIETEA-AKALEKLC--AHTFPLDVTRVESV 306
VTG SG+G A A LA EG + + E A A +E A P D+T +++
Sbjct: 25 VTGASSGIGEATAEALAAEGAHVVLAARRADELAALADRIEDTDGDALVVPTDITDDDAI 84
Query: 307 QEFRKYVLTVLKDNPKY-KFHAVVNNAGVMTVGKYEWMTASMIESPVHVNLLGAMRVISA 483
+ V + +Y + +VNNAGVM + E S + V VNLLG M + A
Sbjct: 85 DDL------VSETVDEYGRIDILVNNAGVMLLEPLERADRSNLRQMVEVNLLGLMNLTHA 138
Query: 484 FLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASKSWPFGVDTMS 639
+P ++ + ++NV S G Q + Y+A+K FGV+ +
Sbjct: 139 VVPIMQ-------DQDAGHVVNVSSVAGRQADADSSGYNATK---FGVNAFT 180
>UniRef50_UPI0000E49D04 Cluster: PREDICTED: hypothetical protein,
partial; n=2; Strongylocentrotus purpuratus|Rep:
PREDICTED: hypothetical protein, partial -
Strongylocentrotus purpuratus
Length = 223
Score = 51.6 bits (118), Expect = 2e-05
Identities = 30/75 (40%), Positives = 39/75 (52%)
Frame = +1
Query: 385 GVMTVGKYEWMTASMIESPVHVNLLGAMRVISAFLPEIRKTAIETTSKPKPRIINVGSHC 564
G+ G+ EW T M + VNL G +RV +AF P +RK+ K RI+N+GS
Sbjct: 58 GISCFGQAEWCTVDMFKRIADVNLWGTVRVTNAFTPLVRKS--------KGRIVNIGSVL 109
Query: 565 GLQPLPAFAAYSASK 609
Q FA YS SK
Sbjct: 110 ARQGTAGFAHYSISK 124
>UniRef50_Q87XV8 Cluster: Oxidoreductase, short-chain
dehydrogenase/reductase family; n=3; Proteobacteria|Rep:
Oxidoreductase, short-chain dehydrogenase/reductase
family - Pseudomonas syringae pv. tomato
Length = 298
Score = 51.6 bits (118), Expect = 2e-05
Identities = 50/176 (28%), Positives = 72/176 (40%)
Frame = +1
Query: 82 QV*IF*IVSAMSVSRLVAVTGCDSGLGWAVAARLAREGFITIAGMHKGIETEAAKALEKL 261
QV F + + V +TG SG G +A L ++GF + G + E A KL
Sbjct: 17 QVCAFPSTHGSRMKKTVLITGASSGFGLLLATHLHQQGF-NVVGTSRYPEKYAGSVRFKL 75
Query: 262 CAHTFPLDVTRVESVQEFRKYVLTVLKDNPKYKFHAVVNNAGVMTVGKYEWMTASMIESP 441
LD+ SVQ F + + + +VNNAG M G E
Sbjct: 76 ----LRLDIDDDSSVQAFTDELFKHIT-----RLDVLVNNAGYMVTGLAEETPIETGRQQ 126
Query: 442 VHVNLLGAMRVISAFLPEIRKTAIETTSKPKPRIINVGSHCGLQPLPAFAAYSASK 609
N G ++V +A LP +R+ + +II V S GL P + Y+ASK
Sbjct: 127 FETNFWGTVKVTNALLPYMRR-------QKNGQIITVSSMVGLIGPPNLSYYAASK 175
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 607,089,651
Number of Sequences: 1657284
Number of extensions: 11927211
Number of successful extensions: 43512
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 40391
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 42055
length of database: 575,637,011
effective HSP length: 97
effective length of database: 414,880,463
effective search space used: 47711253245
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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