Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= bmov10i01
(734 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI00015B605A Cluster: PREDICTED: similar to GA19489-PA... 269 4e-71
UniRef50_UPI0000DB72A4 Cluster: PREDICTED: similar to 3-phosphog... 261 1e-68
UniRef50_A7SFV8 Cluster: Predicted protein; n=1; Nematostella ve... 239 7e-62
UniRef50_O43175 Cluster: D-3-phosphoglycerate dehydrogenase; n=5... 235 1e-60
UniRef50_Q0W4A2 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 200 2e-50
UniRef50_Q3AQU0 Cluster: D-3-phosphoglycerate dehydrogenase; n=5... 193 3e-48
UniRef50_Q58424 Cluster: D-3-phosphoglycerate dehydrogenase; n=7... 191 1e-47
UniRef50_A5UQ03 Cluster: D-3-phosphoglycerate dehydrogenase; n=5... 191 2e-47
UniRef50_A0L7J1 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 190 3e-47
UniRef50_Q3ZX05 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 190 4e-47
UniRef50_A7HDB1 Cluster: D-3-phosphoglycerate dehydrogenase; n=5... 190 4e-47
UniRef50_Q897N8 Cluster: D-3-phosphoglycerate dehydrogenase; n=4... 188 9e-47
UniRef50_Q8PW48 Cluster: D-3-phosphoglycerate dehydrogenase; n=4... 186 7e-46
UniRef50_A2U4T1 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 184 2e-45
UniRef50_A6UQN3 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 182 8e-45
UniRef50_O29445 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 182 8e-45
UniRef50_P73821 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 182 1e-44
UniRef50_Q2AHU0 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 181 1e-44
UniRef50_UPI0000DC0E13 Cluster: 3-phosphoglycerate dehydrogenase... 181 2e-44
UniRef50_Q9X1C1 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 180 3e-44
UniRef50_A1SM51 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 179 6e-44
UniRef50_Q1NQ97 Cluster: D-isomer specific 2-hydroxyacid dehydro... 179 8e-44
UniRef50_A3EWA5 Cluster: Phosphoglycerate dehydrogenase; n=2; Ba... 179 8e-44
UniRef50_Q8YIU3 Cluster: D-3-PHOSPHOGLYCERATE DEHYDROGENASE; n=7... 177 2e-43
UniRef50_Q7UQL2 Cluster: Phosphoglycerate dehydrogenase; n=2; Pl... 177 3e-43
UniRef50_Q1PZY1 Cluster: Similar to D-3-phosphoglycerate dehydro... 174 2e-42
UniRef50_A6C9V4 Cluster: Phosphoglycerate dehydrogenase; n=1; Pl... 174 2e-42
UniRef50_Q67TJ9 Cluster: Phosphoglycerate dehydrogenase; n=1; Sy... 173 4e-42
UniRef50_Q4L766 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 172 7e-42
UniRef50_P35136 Cluster: D-3-phosphoglycerate dehydrogenase; n=8... 172 7e-42
UniRef50_Q8EN61 Cluster: Phosphoglycerate dehydrogenase; n=2; Ba... 171 2e-41
UniRef50_A0LMX1 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 171 2e-41
UniRef50_Q8R716 Cluster: Phosphoglycerate dehydrogenase and rela... 170 3e-41
UniRef50_UPI0000E4762C Cluster: PREDICTED: similar to D-3-phosph... 143 3e-41
UniRef50_Q1IVI0 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 170 3e-41
UniRef50_A1DFM4 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 169 8e-41
UniRef50_O04130 Cluster: D-3-phosphoglycerate dehydrogenase, chl... 168 1e-40
UniRef50_O67741 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 167 2e-40
UniRef50_A7CYD6 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 166 6e-40
UniRef50_Q2LGV1 Cluster: Phosphoglycerate dehydrogenase; n=6; Ha... 165 1e-39
UniRef50_O33116 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 165 1e-39
UniRef50_Q1AXS3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 164 2e-39
UniRef50_A7P9P5 Cluster: Chromosome chr3 scaffold_8, whole genom... 163 4e-39
UniRef50_Q8ZTC7 Cluster: D-3-phosphoglycerate dehydrogenase; n=5... 163 4e-39
UniRef50_UPI00015BAF48 Cluster: D-isomer specific 2-hydroxyacid ... 160 3e-38
UniRef50_A6C2G1 Cluster: Phosphoglycerate dehydrogenase; n=1; Pl... 159 9e-38
UniRef50_A1IDH6 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 158 2e-37
UniRef50_Q8TYK0 Cluster: Predicted dehydrogenase related to phos... 157 3e-37
UniRef50_Q0J5C2 Cluster: Os08g0447000 protein; n=11; Viridiplant... 154 2e-36
UniRef50_Q9RUU0 Cluster: D-3-phosphoglycerate dehydrogenase; n=4... 153 6e-36
UniRef50_A4MA79 Cluster: D-isomer specific 2-hydroxyacid dehydro... 147 3e-34
UniRef50_A4FIF2 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 146 4e-34
UniRef50_A0RW58 Cluster: Phosphoglycerate dehydrogenase; n=3; Cr... 146 5e-34
UniRef50_A6DQ00 Cluster: SerA; n=1; Lentisphaera araneosa HTCC21... 145 9e-34
UniRef50_Q1K3M3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 143 3e-33
UniRef50_Q0EUV6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 143 3e-33
UniRef50_Q97N23 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 138 1e-31
UniRef50_Q8EMJ8 Cluster: Hypothetical conserved protein; n=1; Oc... 138 1e-31
UniRef50_Q97ZK1 Cluster: D-3-phosphoglycerate dehydrogenase; n=4... 136 4e-31
UniRef50_A6PUG1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 132 6e-30
UniRef50_Q5KN70 Cluster: D-3-phosphoglycerate dehydrogenase 2, p... 132 1e-29
UniRef50_A1RDF9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 131 1e-29
UniRef50_A6EBH4 Cluster: Phosphoglycerate dehydrogenase; n=1; Pe... 131 2e-29
UniRef50_A6CKS4 Cluster: Putative uncharacterized protein; n=1; ... 130 3e-29
UniRef50_Q46VE6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 130 5e-29
UniRef50_A1HSQ7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 130 5e-29
UniRef50_Q81T55 Cluster: D-isomer specific 2-hydroxyacid dehydro... 129 6e-29
UniRef50_Q6MN05 Cluster: Phosphoglycerate dehydrogenase; n=1; Bd... 129 8e-29
UniRef50_Q11UL6 Cluster: Phosphoglycerate dehydrogenase; n=1; Cy... 128 1e-28
UniRef50_Q8XPB1 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 126 7e-28
UniRef50_Q0ETU3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 126 7e-28
UniRef50_A6Q7Q2 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 125 1e-27
UniRef50_Q9WYG2 Cluster: Phosphoglycerate dehydrogenase, putativ... 124 2e-27
UniRef50_Q8UJZ6 Cluster: Phosphoglycerate dehydrogenase; n=3; Al... 124 2e-27
UniRef50_A4YUP8 Cluster: Putative D-3-phosphoglycerate dehydroge... 124 2e-27
UniRef50_A1AR04 Cluster: D-isomer specific 2-hydroxyacid dehydro... 123 4e-27
UniRef50_Q18XF4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 122 9e-27
UniRef50_A7HM61 Cluster: Glyoxylate reductase; n=1; Fervidobacte... 121 2e-26
UniRef50_A0V9Y4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 120 4e-26
UniRef50_A0UAW1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 120 4e-26
UniRef50_Q3SK87 Cluster: D-isomer specific 2-hydroxyacid dehydro... 119 6e-26
UniRef50_A7HEG1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 119 6e-26
UniRef50_A4WXD4 Cluster: Dimethylmenaquinone methyltransferase; ... 119 6e-26
UniRef50_A4YFM2 Cluster: D-isomer specific 2-hydroxyacid dehydro... 119 6e-26
UniRef50_Q6W1I8 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 118 1e-25
UniRef50_Q4WHR3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 118 1e-25
UniRef50_Q5V1E2 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 118 2e-25
UniRef50_Q5WLJ2 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 117 3e-25
UniRef50_A2A023 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 117 3e-25
UniRef50_Q7X388 Cluster: Phosphoglycerate dehydrogenase; n=3; Es... 117 3e-25
UniRef50_A7CY19 Cluster: D-isomer specific 2-hydroxyacid dehydro... 116 5e-25
UniRef50_A0LN07 Cluster: D-isomer specific 2-hydroxyacid dehydro... 116 5e-25
UniRef50_Q0RXU8 Cluster: Phosphoglycerate dehydrogenase; n=1; Rh... 116 6e-25
UniRef50_A4FHH0 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 116 6e-25
UniRef50_Q21A61 Cluster: D-isomer specific 2-hydroxyacid dehydro... 116 8e-25
UniRef50_Q03YV3 Cluster: Lactate dehydrogenase related enzyme; n... 115 1e-24
UniRef50_Q65WI5 Cluster: SerA protein; n=1; Mannheimia succinici... 115 1e-24
UniRef50_Q3CIY1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 115 1e-24
UniRef50_Q214B1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 115 1e-24
UniRef50_Q6L245 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 114 2e-24
UniRef50_Q88ZU6 Cluster: Phosphoglycerate dehydrogenase; n=2; La... 114 2e-24
UniRef50_Q49ZM5 Cluster: Putative dehydrogenase; n=1; Staphyloco... 114 2e-24
UniRef50_Q88YI0 Cluster: Phosphoglycerate dehydrogenase; n=5; Ba... 113 3e-24
UniRef50_Q7D366 Cluster: AGR_pAT_578p; n=2; Agrobacterium tumefa... 113 3e-24
UniRef50_A6C853 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 113 3e-24
UniRef50_Q031D4 Cluster: Phosphoglycerate dehydrogenase; n=20; S... 113 6e-24
UniRef50_A0VQR0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 113 6e-24
UniRef50_A1G3C5 Cluster: D-isomer specific 2-hydroxyacid dehydro... 112 1e-23
UniRef50_Q83AZ4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 111 1e-23
UniRef50_Q6A5K9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 111 1e-23
UniRef50_Q0FX01 Cluster: D-isomer specific 2-hydroxyacid dehydro... 111 1e-23
UniRef50_A7NGZ0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 111 1e-23
UniRef50_Q3KBX8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 111 2e-23
UniRef50_Q8Y3L1 Cluster: Lmo2824 protein; n=14; Bacillales|Rep: ... 111 2e-23
UniRef50_O58320 Cluster: Glyoxylate reductase; n=16; cellular or... 111 2e-23
UniRef50_A6ULR7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 110 3e-23
UniRef50_A5N5A9 Cluster: SerA; n=1; Clostridium kluyveri DSM 555... 110 3e-23
UniRef50_Q5KYJ7 Cluster: Dehydrogenase; n=3; Firmicutes|Rep: Deh... 110 4e-23
UniRef50_A5URV2 Cluster: D-isomer specific 2-hydroxyacid dehydro... 109 5e-23
UniRef50_Q9TXJ5 Cluster: D-3-phosphoglycerate dehydrogenase-like... 109 5e-23
UniRef50_A4ARG6 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 109 9e-23
UniRef50_Q7WM64 Cluster: Putative dehydrogenase; n=2; Bordetella... 108 1e-22
UniRef50_A1HM37 Cluster: D-isomer specific 2-hydroxyacid dehydro... 108 1e-22
UniRef50_A1HMI9 Cluster: Phosphoglycerate dehydrogenase; n=1; Th... 108 2e-22
UniRef50_Q825H6 Cluster: Putative glycerate dehydrogenase; n=1; ... 107 2e-22
UniRef50_A1ZGW5 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 107 2e-22
UniRef50_UPI0000DA2A77 Cluster: PREDICTED: similar to D-3-phosph... 107 3e-22
UniRef50_Q82XE1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 106 6e-22
UniRef50_A3ZW64 Cluster: Phosphoglycerate dehydrogenase, putativ... 106 6e-22
UniRef50_Q27SN5 Cluster: Beta xylosidase-like protein; n=1; Acan... 106 6e-22
UniRef50_Q81N95 Cluster: D-3-phosphoglycerate dehydrogenase, put... 105 9e-22
UniRef50_Q1FF19 Cluster: D-isomer specific 2-hydroxyacid dehydro... 105 9e-22
UniRef50_P0A9T3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 105 9e-22
UniRef50_Q82U25 Cluster: D-isomer specific 2-hydroxyacid dehydro... 105 1e-21
UniRef50_A0JVX0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 105 1e-21
UniRef50_A0HBX6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 105 1e-21
UniRef50_A1W9A3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 104 2e-21
UniRef50_Q7UQC8 Cluster: Probable 2-hydroxyacid dehydrogenase; n... 104 3e-21
UniRef50_Q8EP33 Cluster: Glycerate dehydrogenase; n=2; Bacillace... 103 3e-21
UniRef50_Q3DL54 Cluster: Glyoxylate reductase, NADH-dependent; n... 103 3e-21
UniRef50_Q63VJ5 Cluster: D-3-phosphoglycerate dehydrogenase; n=8... 103 5e-21
UniRef50_A5Z3X2 Cluster: Putative uncharacterized protein; n=1; ... 103 5e-21
UniRef50_Q72KT6 Cluster: Glycerate dehydrogenase/glyoxylate redu... 103 6e-21
UniRef50_A3UGW9 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 103 6e-21
UniRef50_Q4AIL7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 102 8e-21
UniRef50_A7IJ69 Cluster: D-isomer specific 2-hydroxyacid dehydro... 102 8e-21
UniRef50_A4FK85 Cluster: D-3-phosphoglycerate dehydrogenase, put... 102 8e-21
UniRef50_Q1WVK4 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 102 1e-20
UniRef50_UPI000023F60F Cluster: hypothetical protein FG08018.1; ... 101 1e-20
UniRef50_A1JTE6 Cluster: Putative oxidoreductase; n=1; Yersinia ... 101 2e-20
UniRef50_A0GVM6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 101 2e-20
UniRef50_UPI00015BD3AA Cluster: UPI00015BD3AA related cluster; n... 100 3e-20
UniRef50_A4AN91 Cluster: Predicted dehydrogenase; n=14; Bacteroi... 100 3e-20
UniRef50_P40054 Cluster: D-3-phosphoglycerate dehydrogenase 1; n... 100 3e-20
UniRef50_Q5FUW5 Cluster: D-3-phosphoglycerate dehydrogenase; n=5... 100 4e-20
UniRef50_Q01W77 Cluster: D-isomer specific 2-hydroxyacid dehydro... 99 6e-20
UniRef50_A6T665 Cluster: Putative D-3-phosphoglycerate dehydroge... 99 6e-20
UniRef50_A0Z6W9 Cluster: Spermidine/putrescine ABC transporter A... 99 6e-20
UniRef50_Q27SS3 Cluster: Glycerate dehydrogenase-like protein; n... 99 6e-20
UniRef50_Q1CG62 Cluster: D-isomer specific 2-hydroxyacid dehydro... 100 7e-20
UniRef50_Q1GAM7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 99 1e-19
UniRef50_Q0C254 Cluster: D-isomer specific 2-hydroxyacid dehydro... 99 1e-19
UniRef50_A6GGA6 Cluster: Probable 2-hydroxyacid dehydrogenase; n... 99 1e-19
UniRef50_A0ZEB8 Cluster: Predicted dehydrogenase; n=6; Cyanobact... 99 1e-19
UniRef50_Q5FUD9 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 98 2e-19
UniRef50_Q9UYH9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 98 2e-19
UniRef50_A7HBU0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 98 2e-19
UniRef50_Q896Z8 Cluster: 2-hydroxyacid dehydrogenase; n=4; Clost... 97 3e-19
UniRef50_Q64UR3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 97 3e-19
UniRef50_Q3A6W9 Cluster: 3-phosphoglycerate dehydrogenase; n=1; ... 97 3e-19
UniRef50_P73990 Cluster: D-isomer specific 2-hydroxyacid dehydro... 97 3e-19
UniRef50_A6UCB8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 97 3e-19
UniRef50_A4S3N1 Cluster: Predicted protein; n=2; Ostreococcus|Re... 97 3e-19
UniRef50_A3JX80 Cluster: D-isomer specific 2-hydroxyacid dehydro... 97 4e-19
UniRef50_A2SRM1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 97 4e-19
UniRef50_Q5FKH9 Cluster: Glyoxylate reductase; n=1; Lactobacillu... 97 5e-19
UniRef50_Q30V14 Cluster: D-isomer specific 2-hydroxyacid dehydro... 97 5e-19
UniRef50_Q0K073 Cluster: D-3-Phosphoglycerate dehydrogenase; n=2... 97 5e-19
UniRef50_A4EQ78 Cluster: Dehydrogenase; n=1; Roseobacter sp. SK2... 97 5e-19
UniRef50_UPI0000D9FBAD Cluster: PREDICTED: similar to 3-phosphog... 96 7e-19
UniRef50_A4RX85 Cluster: Predicted protein; n=3; Ostreococcus|Re... 96 9e-19
UniRef50_O28495 Cluster: 2-hydroxyacid dehydrogenase, putative; ... 96 9e-19
UniRef50_Q0W672 Cluster: Glycerate dehydrogenase; n=2; Archaea|R... 96 9e-19
UniRef50_Q89QF5 Cluster: Blr3173 protein; n=3; Bradyrhizobium|Re... 95 1e-18
UniRef50_A4SWE6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 95 1e-18
UniRef50_Q7WEA3 Cluster: Phosphoglycerate dehydrogenase; n=1; Bo... 95 2e-18
UniRef50_Q11JH0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 95 2e-18
UniRef50_A0JWH0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 95 2e-18
UniRef50_Q6F7L0 Cluster: Glycerate dehydrogenase; n=3; Gammaprot... 95 2e-18
UniRef50_Q44NM9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 95 2e-18
UniRef50_Q8TR50 Cluster: Glycerate dehydrogenase; n=2; Methanosa... 95 2e-18
UniRef50_A4TF35 Cluster: D-isomer specific 2-hydroxyacid dehydro... 94 3e-18
UniRef50_A4EAR0 Cluster: Putative uncharacterized protein; n=1; ... 94 3e-18
UniRef50_A1W7V5 Cluster: D-isomer specific 2-hydroxyacid dehydro... 94 3e-18
UniRef50_Q0CUD5 Cluster: Putative uncharacterized protein; n=1; ... 94 3e-18
UniRef50_A4U158 Cluster: D-isomer specific 2-hydroxyacid dehydro... 94 4e-18
UniRef50_UPI00015B49ED Cluster: PREDICTED: similar to putative g... 93 5e-18
UniRef50_Q8CPW2 Cluster: Glycerate dehydrogenase; n=4; Staphyloc... 93 5e-18
UniRef50_Q49UN3 Cluster: NAD-dependent formate dehydrogenase; n=... 93 5e-18
UniRef50_Q03WU1 Cluster: Lactate dehydrogenase related dehydroge... 93 6e-18
UniRef50_Q12VM6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 93 6e-18
UniRef50_UPI000050F9E4 Cluster: COG0111: Phosphoglycerate dehydr... 93 8e-18
UniRef50_Q74CK1 Cluster: Glycerate dehydrogenase; n=12; Bacteria... 93 8e-18
UniRef50_Q3Y1E6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 93 8e-18
UniRef50_Q5KQ73 Cluster: D-3-phosphoglycerate dehydrogenase, put... 93 8e-18
UniRef50_UPI000023EBBC Cluster: hypothetical protein FG00146.1; ... 92 1e-17
UniRef50_Q120S8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 92 1e-17
UniRef50_A3IA61 Cluster: D-3 phosphoglycerate dehydrogenase; n=1... 92 1e-17
UniRef50_A0AFI6 Cluster: Complete genome; n=1; Listeria welshime... 92 1e-17
UniRef50_Q8ZXX8 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 92 1e-17
UniRef50_Q8YK31 Cluster: Glycerate dehydrogenase; n=3; Cyanobact... 91 2e-17
UniRef50_Q04DF1 Cluster: Lactate dehydrogenase related enzyme; n... 91 2e-17
UniRef50_A1UEI9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 91 2e-17
UniRef50_A4FIJ9 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 91 3e-17
UniRef50_Q76KF5 Cluster: D-phosphoglycerate dehydrogenase; n=2; ... 91 3e-17
UniRef50_A7CR80 Cluster: D-isomer specific 2-hydroxyacid dehydro... 91 3e-17
UniRef50_A6PPS4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 91 3e-17
UniRef50_A2F8V0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 91 3e-17
UniRef50_Q89EL0 Cluster: Blr7063 protein; n=1; Bradyrhizobium ja... 90 5e-17
UniRef50_Q9HK29 Cluster: 2-hydroxyacid dehydrogenase related pro... 90 5e-17
UniRef50_A7D498 Cluster: D-isomer specific 2-hydroxyacid dehydro... 90 5e-17
UniRef50_Q89LI6 Cluster: Blr4558 protein; n=6; Bradyrhizobiaceae... 90 6e-17
UniRef50_Q6AMI7 Cluster: Related to D-3-phosphoglycerate dehydro... 90 6e-17
UniRef50_A3PPC6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 90 6e-17
UniRef50_A6G5P3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 89 8e-17
UniRef50_A0FZA8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 89 8e-17
UniRef50_Q2S4U0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 89 1e-16
UniRef50_A6LZ51 Cluster: D-isomer specific 2-hydroxyacid dehydro... 89 1e-16
UniRef50_A5V6T9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 89 1e-16
UniRef50_Q98LH4 Cluster: Phosphoglycerate dehydrogenase; n=3; Me... 89 1e-16
UniRef50_Q2LUG0 Cluster: 2-hydroxyacid dehydrogenase, D-isomer s... 89 1e-16
UniRef50_Q5ZYW9 Cluster: D-3-phosphoglycerate dehydrogenase; n=3... 88 2e-16
UniRef50_Q1MQK2 Cluster: Phosphoglycerate dehydrogenase and rela... 88 2e-16
UniRef50_Q0FY56 Cluster: Putative phosphoglycerate dehydrogenase... 88 2e-16
UniRef50_A7BQE7 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 88 2e-16
UniRef50_A1AQ02 Cluster: D-isomer specific 2-hydroxyacid dehydro... 88 2e-16
UniRef50_Q20595 Cluster: Putative uncharacterized protein; n=3; ... 88 2e-16
UniRef50_Q6A895 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 88 2e-16
UniRef50_Q6KZ29 Cluster: Gluconate 2-dehydrogenase; n=3; Archaea... 88 2e-16
UniRef50_A4AQJ2 Cluster: D-lactate dehydrogenase; n=1; Flavobact... 87 3e-16
UniRef50_Q4PK14 Cluster: Predicted D-isomer specific 2-hydroxyac... 87 4e-16
UniRef50_A0Y9Y1 Cluster: Glyoxylate reductase; n=2; unclassified... 87 4e-16
UniRef50_A0HB22 Cluster: D-isomer specific 2-hydroxyacid dehydro... 87 4e-16
UniRef50_Q5HW94 Cluster: D-isomer specific 2-hydroxyacid dehydro... 87 6e-16
UniRef50_A7AAD2 Cluster: Putative uncharacterized protein; n=1; ... 87 6e-16
UniRef50_Q5LT44 Cluster: D-isomer specific 2-hydroxyacid dehydro... 86 7e-16
UniRef50_Q3S8E5 Cluster: Putative D-isomer specific 2-hydroxyaci... 86 7e-16
UniRef50_Q0FF66 Cluster: Glycolate reductase; n=2; Alphaproteoba... 86 7e-16
UniRef50_A6CRV0 Cluster: 2-hydroxyacid dehydrogenase; n=15; Baci... 86 7e-16
UniRef50_A5ZA39 Cluster: Putative uncharacterized protein; n=1; ... 86 7e-16
UniRef50_Q5KE95 Cluster: Phosphoglycerate dehydrogenase; n=2; Fi... 86 7e-16
UniRef50_A1RC54 Cluster: Glyoxylate reductase; n=2; Actinomyceta... 86 1e-15
UniRef50_A3H6F3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 86 1e-15
UniRef50_Q8R8Q2 Cluster: Lactate dehydrogenase and related dehyd... 85 1e-15
UniRef50_Q81K70 Cluster: D-isomer specific 2-hydroxyacid dehydro... 85 1e-15
UniRef50_Q7WNI7 Cluster: Putative dehydrogenase; n=1; Bordetella... 85 1e-15
UniRef50_A0RUD3 Cluster: 2 lactate dehydrogenase; n=2; Thermopro... 85 1e-15
UniRef50_Q4IXK9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 85 2e-15
UniRef50_A5G0Z0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 85 2e-15
UniRef50_A3K878 Cluster: 2-hydroxyacid dehydrogenase; n=1; Sagit... 85 2e-15
UniRef50_A1HQU2 Cluster: Glyoxylate reductase; n=1; Thermosinus ... 85 2e-15
UniRef50_Q9K7P7 Cluster: Glycerate dehydrogenase; n=8; Bacillace... 85 2e-15
UniRef50_Q7MT26 Cluster: D-isomer specific 2-hydroxyacid dehydro... 85 2e-15
UniRef50_O34815 Cluster: YoaD; n=2; Bacillus|Rep: YoaD - Bacillu... 85 2e-15
UniRef50_A5UPU9 Cluster: Glyoxylate reductase; n=12; Bacteria|Re... 85 2e-15
UniRef50_Q4PP80 Cluster: Putative glyoxylate reductase/hydroxypy... 85 2e-15
UniRef50_Q39LG4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 84 3e-15
UniRef50_Q0B1Q1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 84 3e-15
UniRef50_Q04AA8 Cluster: Lactate dehydrogenase related enzyme; n... 84 3e-15
UniRef50_O86322 Cluster: POSSIBLE D-3-PHOSPHOGLYCERATE DEHYDROGE... 84 4e-15
UniRef50_Q1VRN5 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 84 4e-15
UniRef50_Q986P2 Cluster: Phosphoglycerate dehydrogenase; n=14; c... 83 5e-15
UniRef50_A4AL46 Cluster: Putative dehydrogenase; n=1; marine act... 83 5e-15
UniRef50_Q97F10 Cluster: Possible phosphoglycerate dehydrogenase... 83 7e-15
UniRef50_Q5U922 Cluster: (R)-2-hydroxyisocaproate dehydrogenase;... 83 7e-15
UniRef50_A6W4F1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 83 7e-15
UniRef50_P13443 Cluster: Glycerate dehydrogenase; n=15; Viridipl... 83 7e-15
UniRef50_Q8GQX5 Cluster: 2-oxo-4-phenylbutanoate reductase; n=2;... 83 9e-15
UniRef50_Q5IW39 Cluster: Putative PhpE; n=2; Actinomycetales|Rep... 83 9e-15
UniRef50_A3PDQ1 Cluster: Putative dehydrogenase; n=1; Prochloroc... 83 9e-15
UniRef50_Q73M93 Cluster: Glycerate dehydrogenase; n=3; Bacteria|... 82 1e-14
UniRef50_A4ETV8 Cluster: Putative uncharacterized protein; n=6; ... 82 2e-14
UniRef50_Q8EMJ4 Cluster: 2-ketogluconate reductase; n=1; Oceanob... 81 2e-14
UniRef50_Q7W397 Cluster: Putative 2-hydroxyacid dehydrogenase; n... 81 2e-14
UniRef50_Q126V3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 81 2e-14
UniRef50_Q11QU3 Cluster: D-lactate dehydrogenase; n=1; Cytophaga... 81 2e-14
UniRef50_A0GDF1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 81 2e-14
UniRef50_Q59516 Cluster: Glycerate dehydrogenase; n=23; Proteoba... 81 2e-14
UniRef50_O66939 Cluster: D-lactate dehydrogenase; n=1; Aquifex a... 81 3e-14
UniRef50_Q125T3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 81 3e-14
UniRef50_A0Z2L3 Cluster: Putative uncharacterized protein; n=1; ... 81 3e-14
UniRef50_Q8YEC6 Cluster: Gluconate 2-dehydrogenase; n=72; Alphap... 81 4e-14
UniRef50_A7UH56 Cluster: Putative 2-hydroxy acid dehydrogenase; ... 81 4e-14
UniRef50_A7EUN0 Cluster: Formate dehydrogenase; n=2; Sclerotinia... 81 4e-14
UniRef50_Q8F5N8 Cluster: Phosphoglycerate dehydrogenase; n=4; Le... 80 5e-14
UniRef50_Q7NEV2 Cluster: Phosphoglycerate dehydrogenase; n=6; Ba... 80 5e-14
UniRef50_Q13ZE9 Cluster: Putative dehydrogenase, D-3-phosphoglyc... 80 5e-14
UniRef50_Q8MR05 Cluster: LD48009p; n=11; Coelomata|Rep: LD48009p... 80 5e-14
UniRef50_Q5KFZ5 Cluster: Phosphoglycerate dehydrogenase, putativ... 80 5e-14
UniRef50_Q6LYW5 Cluster: 2-hydroxyacid dehydrogenase, D-isomer s... 80 5e-14
UniRef50_O69054 Cluster: Phosphonate dehydrogenase; n=16; Bacter... 80 5e-14
UniRef50_Q9K1Q1 Cluster: Glycerate dehydrogenase; n=6; cellular ... 80 6e-14
UniRef50_Q03U10 Cluster: 2-hydroxyacid dehydrogenase; n=1; Lacto... 80 6e-14
UniRef50_A7FYM9 Cluster: D-lactate dehydrogenase; n=4; Clostridi... 80 6e-14
UniRef50_P36234 Cluster: Glycerate dehydrogenase; n=2; Hyphomicr... 80 6e-14
UniRef50_Q9S2M5 Cluster: Putative D-lactate dehydrogenase; n=1; ... 79 8e-14
UniRef50_Q8EMM3 Cluster: Dehydrogenase; n=2; cellular organisms|... 79 8e-14
UniRef50_Q5WAF3 Cluster: 2-ketogluconate reductase; n=1; Bacillu... 79 8e-14
UniRef50_Q47W88 Cluster: D-isomer specific 2-hydroxyacid dehydro... 79 8e-14
UniRef50_Q1V097 Cluster: Phosphoglycerate dehydrogenase; n=2; Ca... 79 8e-14
UniRef50_A5MYX9 Cluster: Putative uncharacterized protein; n=1; ... 79 8e-14
UniRef50_Q5BU19 Cluster: Ribeye a protein; n=4; Clupeocephala|Re... 79 1e-13
UniRef50_Q82XY9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 79 1e-13
UniRef50_Q1MPI0 Cluster: Lactate dehydrogenase and related dehyd... 79 1e-13
UniRef50_A3RV54 Cluster: 2-hydroxyacid dehydrogenase; n=5; Burkh... 79 1e-13
UniRef50_Q0VQC3 Cluster: Erythronate-4-phosphate dehydrogenase; ... 79 1e-13
UniRef50_Q82ZC3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 79 1e-13
UniRef50_A3ZMM2 Cluster: Dehydrogenase; n=1; Blastopirellula mar... 79 1e-13
UniRef50_A2QX18 Cluster: Contig An11c0250, complete genome; n=3;... 79 1e-13
UniRef50_Q1LCR9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 78 2e-13
UniRef50_P56545 Cluster: C-terminal-binding protein 2; n=98; Coe... 78 2e-13
UniRef50_A1ZX42 Cluster: Glycerate dehydrogenase; n=1; Microscil... 78 3e-13
UniRef50_A7S382 Cluster: Predicted protein; n=3; Eumetazoa|Rep: ... 78 3e-13
UniRef50_Q6MY49 Cluster: NAD-dependant D-isomer specific 2-hydro... 78 3e-13
UniRef50_Q9HVG5 Cluster: Glycerate dehydrogenase; n=23; Gammapro... 77 3e-13
UniRef50_Q483F8 Cluster: Putative glyoxylate reductase; n=1; Col... 77 3e-13
UniRef50_Q2RTD0 Cluster: Glycolate reductase; n=8; Alphaproteoba... 77 3e-13
UniRef50_A4TXP1 Cluster: Glycolate reductase; n=1; Magnetospiril... 77 3e-13
UniRef50_A0L0H4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 77 3e-13
UniRef50_P44501 Cluster: 2-hydroxyacid dehydrogenase homolog; n=... 77 3e-13
UniRef50_Q4FNZ3 Cluster: Probable dehydrogenase; n=2; Candidatus... 77 5e-13
UniRef50_Q03XJ7 Cluster: 2-hydroxyacid dehydrogenase; n=3; Lacto... 77 5e-13
UniRef50_A4SW26 Cluster: D-isomer specific 2-hydroxyacid dehydro... 77 5e-13
UniRef50_Q6FFP8 Cluster: Putative 2-hydroxyacid dehydrogenase; n... 77 6e-13
UniRef50_Q5QU97 Cluster: 2-hydroxyacid dehydrogenase; n=4; Gamma... 77 6e-13
UniRef50_Q579J7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 77 6e-13
UniRef50_Q2S4S4 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 77 6e-13
UniRef50_Q0FUK3 Cluster: Predicted dehydrogenase; n=3; Rhodobact... 77 6e-13
UniRef50_A1S0J0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 77 6e-13
UniRef50_P30799 Cluster: 2-hydroxyacid dehydrogenase homolog; n=... 77 6e-13
UniRef50_Q0PQJ5 Cluster: D-isomer specific 2-hydroxyacid dehydro... 76 8e-13
UniRef50_A1FGW0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 76 8e-13
UniRef50_O32264 Cluster: Probable 2-ketogluconate reductase; n=1... 76 8e-13
UniRef50_Q3KAR6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 76 1e-12
UniRef50_O24922 Cluster: Phosphoglycerate dehydrogenase; n=4; He... 76 1e-12
UniRef50_Q1GJ08 Cluster: D-isomer specific 2-hydroxyacid dehydro... 76 1e-12
UniRef50_A1RBK7 Cluster: Putative 2-hydroxyacid-family dehydroge... 76 1e-12
UniRef50_Q752A0 Cluster: AFR675Wp; n=3; Saccharomycetales|Rep: A... 76 1e-12
UniRef50_Q89388 Cluster: A53R protein; n=3; Chlorovirus|Rep: A53... 75 1e-12
UniRef50_Q883D2 Cluster: D-isomer specific 2-hydroxyacid dehydro... 75 1e-12
UniRef50_Q63YS2 Cluster: D-isomer specific 2-hydroxyacid dehydro... 75 1e-12
UniRef50_A1SPF8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 75 1e-12
UniRef50_Q88VJ2 Cluster: D-lactate dehydrogenase; n=27; Lactobac... 75 1e-12
UniRef50_Q9UBQ7 Cluster: Glyoxylate reductase/hydroxypyruvate re... 75 1e-12
UniRef50_P17584 Cluster: D-2-hydroxyisocaproate dehydrogenase; n... 75 1e-12
UniRef50_Q8FPW0 Cluster: Putative uncharacterized protein; n=1; ... 75 2e-12
UniRef50_Q398N2 Cluster: D-isomer specific 2-hydroxyacid dehydro... 75 2e-12
UniRef50_Q11JF3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 75 2e-12
UniRef50_A6CXX0 Cluster: Dehydrogenase; n=1; Vibrio shilonii AK1... 75 2e-12
UniRef50_A0QQ27 Cluster: Glyoxylate reductase; n=4; Mycobacteriu... 75 2e-12
UniRef50_A7P8C8 Cluster: Chromosome chr3 scaffold_8, whole genom... 75 2e-12
UniRef50_Q2S0U3 Cluster: Erythronate-4-phosphate dehydrogenase; ... 75 2e-12
UniRef50_Q6FCL4 Cluster: 2-keto-D-gluconate reductase; n=15; Pse... 75 2e-12
UniRef50_A2FHI8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 75 2e-12
UniRef50_Q2KZD5 Cluster: Putative reductase precursor; n=1; Bord... 74 3e-12
UniRef50_Q12CS0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 74 3e-12
UniRef50_A6TVU1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 74 3e-12
UniRef50_Q87MN8 Cluster: Erythronate-4-phosphate dehydrogenase; ... 74 3e-12
UniRef50_Q8ECR2 Cluster: Erythronate-4-phosphate dehydrogenase; ... 74 3e-12
UniRef50_Q6F943 Cluster: Erythronate-4-phosphate dehydrogenase; ... 74 3e-12
UniRef50_Q7MV92 Cluster: Glycerate dehydrogenase; n=1; Porphyrom... 74 4e-12
UniRef50_Q1R7K3 Cluster: 2-hydroxyacid dehydrogenase; n=7; Enter... 74 4e-12
UniRef50_A5ZQ76 Cluster: Putative uncharacterized protein; n=2; ... 74 4e-12
UniRef50_A4A9T4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 74 4e-12
UniRef50_Q6CDS0 Cluster: Similar to tr|O94020 Candida albicans Y... 74 4e-12
UniRef50_Q9HJV5 Cluster: Glycerate dehydrogenase related protein... 74 4e-12
UniRef50_O83080 Cluster: D-lactate dehydrogenase; n=1; Treponema... 74 4e-12
UniRef50_P52643 Cluster: D-lactate dehydrogenase; n=118; cellula... 74 4e-12
UniRef50_Q5FTU6 Cluster: Putative 2-hydroxyacid dehydrogenase; n... 73 6e-12
UniRef50_Q126C0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 73 6e-12
UniRef50_A7HWK6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 73 6e-12
UniRef50_A6FZB7 Cluster: Putative dehydrogenase; n=1; Plesiocyst... 73 6e-12
UniRef50_A0QVE9 Cluster: Glyoxylate reductase; n=1; Mycobacteriu... 73 6e-12
UniRef50_A0NLL6 Cluster: Glycerate dehydrogenase; n=1; Stappia a... 73 6e-12
UniRef50_Q00TL2 Cluster: D-isomer specific 2-hydroxyacid dehydro... 73 6e-12
UniRef50_Q9KP72 Cluster: 2-hydroxyacid dehydrogenase family prot... 73 7e-12
UniRef50_Q67M76 Cluster: Phosphoglycerate dehydrogenase, N-termi... 73 7e-12
UniRef50_Q3IFC5 Cluster: 2-hydroxyacid dehydrogenase family prot... 73 7e-12
UniRef50_A5G073 Cluster: D-isomer specific 2-hydroxyacid dehydro... 73 7e-12
UniRef50_Q9KEA4 Cluster: D-3-phosphoglycerate dehydrogenase; n=1... 73 1e-11
UniRef50_Q11GX7 Cluster: D-isomer specific 2-hydroxyacid dehydro... 73 1e-11
UniRef50_A6DBV6 Cluster: D-lactate dehydrogenase; n=1; Caminibac... 73 1e-11
UniRef50_A5WBM9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 73 1e-11
UniRef50_Q6MIG3 Cluster: Hxdroxypyruvate reductase; n=1; Bdellov... 72 1e-11
UniRef50_Q12E23 Cluster: D-isomer specific 2-hydroxyacid dehydro... 72 1e-11
UniRef50_A6G855 Cluster: Erythronate-4-phosphate dehydrogenase; ... 72 1e-11
UniRef50_A1SW94 Cluster: Erythronate-4-phosphate dehydrogenase; ... 72 1e-11
UniRef50_Q931A1 Cluster: Putative; n=2; Rhizobiales|Rep: Putativ... 72 2e-11
UniRef50_Q89J71 Cluster: 2-hydroxyacid dehydrogenase; n=8; Brady... 72 2e-11
UniRef50_Q0RXQ1 Cluster: Probable phosphoglycerate dehydrogenase... 72 2e-11
UniRef50_A5ZAJ9 Cluster: Putative uncharacterized protein; n=1; ... 72 2e-11
UniRef50_A5N6P2 Cluster: GyaR; n=1; Clostridium kluyveri DSM 555... 72 2e-11
UniRef50_A3Y4H8 Cluster: Erythronate-4-phosphate dehydrogenase; ... 72 2e-11
UniRef50_A5YST2 Cluster: Phosphoglycerate dehydrogenase; n=2; Ha... 72 2e-11
UniRef50_Q6LNU2 Cluster: Erythronate-4-phosphate dehydrogenase; ... 72 2e-11
UniRef50_Q1QXV7 Cluster: Erythronate-4-phosphate dehydrogenase; ... 72 2e-11
UniRef50_Q65DI9 Cluster: YoaD; n=1; Bacillus licheniformis ATCC ... 71 2e-11
UniRef50_Q397E0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 71 2e-11
UniRef50_A0PVI8 Cluster: D-3-phosphoglycerate dehydrogenase SerA... 71 2e-11
UniRef50_Q1E5G6 Cluster: Putative uncharacterized protein; n=1; ... 71 2e-11
UniRef50_Q4LAE6 Cluster: Similar to glycerate dehydrogenase; n=1... 71 3e-11
UniRef50_Q2NVC4 Cluster: Putative 2-hydroxyacid-family dehydroge... 71 3e-11
UniRef50_A4BPX8 Cluster: Glycerate dehydrogenase; n=1; Nitrococc... 71 3e-11
UniRef50_Q4WMF4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 71 3e-11
UniRef50_Q4IV69 Cluster: D-isomer specific 2-hydroxyacid dehydro... 71 4e-11
UniRef50_A6Q114 Cluster: D-isomer specific 2-hydroxyacid dehydro... 71 4e-11
UniRef50_A6BZW2 Cluster: Putative dehydrogenase; n=1; Planctomyc... 71 4e-11
UniRef50_A5P5Y8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 71 4e-11
UniRef50_A3XKE7 Cluster: D-lactate dehydrogenase; n=3; Bacteria|... 71 4e-11
UniRef50_Q22CX9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 70 5e-11
UniRef50_O50096 Cluster: Putative uncharacterized protein PH1388... 70 5e-11
UniRef50_Q5LQR6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 70 7e-11
UniRef50_A4AK07 Cluster: Glycerate dehydrogenase; n=1; marine ac... 70 7e-11
UniRef50_A0Q8P3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 70 7e-11
UniRef50_UPI0000384B5F Cluster: COG0111: Phosphoglycerate dehydr... 69 9e-11
UniRef50_UPI000023E18D Cluster: hypothetical protein FG04024.1; ... 69 9e-11
UniRef50_Q981W5 Cluster: Phosphoglycerate dehydrogenase; n=1; Me... 69 9e-11
UniRef50_A5TUT7 Cluster: Dehydrogenase; n=4; Fusobacterium nucle... 69 9e-11
UniRef50_Q3IF36 Cluster: Erythronate-4-phosphate dehydrogenase; ... 69 9e-11
UniRef50_Q8U6W5 Cluster: 2-hydroxyacid dehydrogenase; n=3; Alpha... 69 1e-10
UniRef50_Q39JN8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 69 1e-10
UniRef50_Q5KKI9 Cluster: 2-hydroxyacid dehydrogenase, putative; ... 69 1e-10
UniRef50_A4R1I1 Cluster: Putative uncharacterized protein; n=1; ... 69 1e-10
UniRef50_P58220 Cluster: 2-ketogluconate reductase; n=75; Proteo... 69 1e-10
UniRef50_Q5QUE2 Cluster: Erythronate-4-phosphate dehydrogenase; ... 69 1e-10
UniRef50_Q8G427 Cluster: Possible 2-hydroxyacid dehydrogenase; n... 69 2e-10
UniRef50_Q2BHH2 Cluster: Glycerate dehydrogenase; n=1; Neptuniib... 69 2e-10
UniRef50_A6Q6K4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 69 2e-10
UniRef50_Q9C7T6 Cluster: Phosphoglycerate dehydrogenase, putativ... 69 2e-10
UniRef50_Q6BTY7 Cluster: Debaryomyces hansenii chromosome C of s... 69 2e-10
UniRef50_A0YEL9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 68 2e-10
UniRef50_Q7Z019 Cluster: Putative D-lactate dehydrogenase; n=1; ... 68 2e-10
UniRef50_Q17CL5 Cluster: Glyoxylate/hydroxypyruvate reductase; n... 68 2e-10
UniRef50_Q62LV8 Cluster: Glyoxylate reductase; n=53; cellular or... 68 3e-10
UniRef50_A1WAF9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 68 3e-10
UniRef50_Q893I3 Cluster: D-lactate dehydrogenase; n=2; Firmicute... 67 4e-10
UniRef50_Q0D7C9 Cluster: Os07g0264100 protein; n=5; Oryza sativa... 67 4e-10
UniRef50_Q99ZM2 Cluster: D-lactate dehydrogenase; n=7; Streptoco... 67 4e-10
UniRef50_Q1V300 Cluster: D-3-phosphoglycerate dehydrogenase; n=2... 67 5e-10
UniRef50_Q036G7 Cluster: Lactate dehydrogenase related 2-hydroxy... 67 5e-10
UniRef50_Q76KF6 Cluster: D-glycerate dehydrogenase; n=4; Entamoe... 67 5e-10
UniRef50_A6QVW0 Cluster: Putative uncharacterized protein; n=1; ... 67 5e-10
UniRef50_Q9HSS1 Cluster: Phosphoglycerate dehydrogenase; n=1; Ha... 67 5e-10
UniRef50_Q7P6Z0 Cluster: D-lactate dehydrogenase; n=10; Bacteria... 66 6e-10
UniRef50_Q1FLB8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 66 6e-10
UniRef50_A5V093 Cluster: D-isomer specific 2-hydroxyacid dehydro... 66 6e-10
UniRef50_Q8LL97 Cluster: Putative uncharacterized protein; n=1; ... 66 6e-10
UniRef50_Q7X9L3 Cluster: Formate dehydrogenase; n=4; Magnoliophy... 66 6e-10
UniRef50_Q2UDC2 Cluster: Glyoxylate/hydroxypyruvate reductase; n... 66 6e-10
UniRef50_Q03UK9 Cluster: Lactate dehydrogenase; n=3; Leuconostoc... 66 8e-10
UniRef50_A4BI79 Cluster: D-lactate dehydrogenase; n=1; Reinekea ... 66 8e-10
UniRef50_A1FCW9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 66 8e-10
UniRef50_Q54UF7 Cluster: Putative uncharacterized protein; n=1; ... 66 8e-10
UniRef50_Q4P752 Cluster: Putative uncharacterized protein; n=1; ... 66 8e-10
UniRef50_O94574 Cluster: Putative 2-hydroxyacid dehydrogenase C1... 66 8e-10
UniRef50_UPI0000587CB1 Cluster: PREDICTED: hypothetical protein;... 66 1e-09
UniRef50_Q8XN08 Cluster: D-lactate dehydrogenase; n=4; Firmicute... 66 1e-09
UniRef50_Q5LSR6 Cluster: D-isomer specific 2-hydroxyacid dehydro... 66 1e-09
UniRef50_Q0LSC3 Cluster: D-isomer specific 2-hydroxyacid dehydro... 66 1e-09
UniRef50_Q9LE33 Cluster: T12C24.9; n=6; core eudicotyledons|Rep:... 66 1e-09
UniRef50_Q9BLF6 Cluster: D-lactate dehydrogenase; n=1; Octopus v... 66 1e-09
UniRef50_A6QZ02 Cluster: Predicted protein; n=2; Onygenales|Rep:... 66 1e-09
UniRef50_Q9RJA1 Cluster: Putative 2-hydroxyacid-family dehydroge... 65 1e-09
UniRef50_Q8RC97 Cluster: Phosphoglycerate dehydrogenase and rela... 65 1e-09
UniRef50_Q11SX0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 65 1e-09
UniRef50_A7CUT0 Cluster: D-isomer specific 2-hydroxyacid dehydro... 65 1e-09
UniRef50_P45250 Cluster: Putative 2-hydroxyacid dehydrogenase HI... 65 1e-09
UniRef50_Q98GE4 Cluster: Phosphoglycerate dehydrogenase; n=5; Rh... 65 2e-09
UniRef50_Q8RG31 Cluster: 2-hydroxyglutarate dehydrogenase; n=4; ... 65 2e-09
UniRef50_Q87JV4 Cluster: D-lactate dehydrogenase; n=6; Vibrio|Re... 65 2e-09
UniRef50_Q7M7Q8 Cluster: PUTATIVE D-2-HYDROXYACID DEHYDROGENASE;... 65 2e-09
UniRef50_Q1M4L9 Cluster: Putative glyoxylate reductase; n=1; Rhi... 65 2e-09
UniRef50_A3VA29 Cluster: D-isomer specific 2-hydroxyacid dehydro... 65 2e-09
UniRef50_A1WHT1 Cluster: D-isomer specific 2-hydroxyacid dehydro... 65 2e-09
UniRef50_Q120Q8 Cluster: D-isomer specific 2-hydroxyacid dehydro... 64 3e-09
UniRef50_A5ZAS1 Cluster: Putative uncharacterized protein; n=1; ... 64 3e-09
UniRef50_A4QT80 Cluster: Putative uncharacterized protein; n=2; ... 64 3e-09
UniRef50_Q13QJ6 Cluster: Putative dehydrogenase; n=1; Burkholder... 64 3e-09
UniRef50_A6W9Y4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 64 3e-09
UniRef50_A6PLZ4 Cluster: D-isomer specific 2-hydroxyacid dehydro... 64 3e-09
UniRef50_A2SEV8 Cluster: Phosphoglycerate dehydrogenase-related ... 64 3e-09
UniRef50_A7STU0 Cluster: Predicted protein; n=5; Nematostella ve... 64 3e-09
UniRef50_Q4FV16 Cluster: Erythronate-4-phosphate dehydrogenase; ... 64 3e-09
UniRef50_Q47XK1 Cluster: Erythronate-4-phosphate dehydrogenase; ... 64 3e-09
UniRef50_Q7VRU9 Cluster: Erythronate-4-phosphate dehydrogenase; ... 64 3e-09
UniRef50_UPI000038E31A Cluster: hypothetical protein Faci_030017... 64 4e-09
UniRef50_Q8UBA7 Cluster: 2-hydroxyacid-family dehydrogenase; n=5... 64 4e-09
UniRef50_Q2BM60 Cluster: Erythronate-4-phosphate dehydrogenase; ... 64 4e-09
UniRef50_A5G1C9 Cluster: D-isomer specific 2-hydroxyacid dehydro... 64 4e-09
UniRef50_A0YAX4 Cluster: Phosphoglycerate dehydrogenase and rela... 64 4e-09
>UniRef50_UPI00015B605A Cluster: PREDICTED: similar to GA19489-PA;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
GA19489-PA - Nasonia vitripennis
Length = 511
Score = 269 bits (660), Expect = 4e-71
Identities = 125/218 (57%), Positives = 162/218 (74%)
Frame = +2
Query: 74 MVVDIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTK 253
M V+++SVL+ D V +CA LL ++G+ TTK K+SKEEL+ E+ HD L+VRS T+VT
Sbjct: 1 MSVNLRSVLVSDPVDERCAALLTSHGVPVTTKYKLSKEELINELQKHDGLIVRSETKVTA 60
Query: 254 EVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHV 433
+V+ A LK+VGRAG GVDNID+ +A + G+ V+N PG N++SACELTC ++ LAR+V
Sbjct: 61 DVIAASPNLKLVGRAGTGVDNIDIPAATRNGILVLNTPGGNSVSACELTCAVISALARNV 120
Query: 434 VPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSAD 613
V A ++K GRWDR LY G EL+GK L ++G GR+GREVA RM AFGM II +DPF + +
Sbjct: 121 VQAGQSMKEGRWDRKLYAGRELSGKALGVVGFGRIGREVAHRMKAFGMEIIAYDPFFTKE 180
Query: 614 QCAQFHCTKMELEDIWPLADYITLHTPLIXSTRNFINA 727
Q AQ TK ELEDIW ADYIT+HTPLI T+N INA
Sbjct: 181 QAAQIGVTKGELEDIWKNADYITVHTPLIPQTKNLINA 218
>UniRef50_UPI0000DB72A4 Cluster: PREDICTED: similar to
3-phosphoglycerate dehydrogenase; n=1; Apis
mellifera|Rep: PREDICTED: similar to 3-phosphoglycerate
dehydrogenase - Apis mellifera
Length = 478
Score = 261 bits (639), Expect = 1e-68
Identities = 122/218 (55%), Positives = 161/218 (73%)
Frame = +2
Query: 74 MVVDIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTK 253
M ++SVLI D V A C ELL +GI TTK K+SKE+L+ E+ NH+ L+VRS T+VT
Sbjct: 1 MSTTLRSVLISDPVDACCGELLVRHGIPVTTKYKLSKEKLIKELQNHEGLIVRSETKVTA 60
Query: 254 EVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHV 433
+V L+VVGRAG GVDNID+++A +KGV V+N PG N++SACELTC L+ LAR+V
Sbjct: 61 DVFACCPNLRVVGRAGTGVDNIDLEAATRKGVIVLNTPGGNSISACELTCALISNLARNV 120
Query: 434 VPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSAD 613
A +LK GRWDR LY+G EL+GKTLA+LG+GR+GREV RM A+GM +I FDP ++++
Sbjct: 121 TQAVQSLKDGRWDRKLYSGFELSGKTLAVLGMGRIGREVTRRMQAYGMRVIAFDPLLTSE 180
Query: 614 QCAQFHCTKMELEDIWPLADYITLHTPLIXSTRNFINA 727
+ K L++IWP+ADYIT+HTPLI T+N INA
Sbjct: 181 DANYLNVEKFSLDEIWPMADYITVHTPLIPQTKNLINA 218
>UniRef50_A7SFV8 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 487
Score = 239 bits (584), Expect = 7e-62
Identities = 112/215 (52%), Positives = 149/215 (69%)
Frame = +2
Query: 80 VDIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEV 259
+++K VLI D V + C +L G+ K+SKEEL+ EIP +D L+VRSAT+V+++V
Sbjct: 4 LELKRVLISDSVDSCCKTILERNGVTVDVNTKLSKEELVSEIPKYDGLIVRSATKVSEDV 63
Query: 260 LDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVP 439
+ AG LK++GRAG GVDNID +A GV V+N PG N LSA E TC L+ LARH+
Sbjct: 64 IKAGKNLKIIGRAGTGVDNIDTVAASLHGVLVMNTPGGNTLSAAEHTCALISSLARHIPQ 123
Query: 440 ASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQC 619
AS + K G+W+R + G+EL GKTLAI+GLGR+GREVA RM ++G+ IG+DP VS
Sbjct: 124 ASASTKEGKWERKQFMGNELFGKTLAIIGLGRIGREVALRMQSYGVKTIGYDPLVSPQDA 183
Query: 620 AQFHCTKMELEDIWPLADYITLHTPLIXSTRNFIN 724
A+ + ME E IWPLADYIT+H PLI T+ +N
Sbjct: 184 AESNIEWMETEKIWPLADYITVHVPLIPPTKGMLN 218
>UniRef50_O43175 Cluster: D-3-phosphoglycerate dehydrogenase; n=53;
Bilateria|Rep: D-3-phosphoglycerate dehydrogenase - Homo
sapiens (Human)
Length = 533
Score = 235 bits (574), Expect = 1e-60
Identities = 106/214 (49%), Positives = 155/214 (72%)
Frame = +2
Query: 83 DIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVL 262
+++ VLI D + C ++L G+ K +SKEEL+ E+ + + L+VRSAT+VT +V+
Sbjct: 5 NLRKVLISDSLDPCCRKILQDGGLQVVEKQNLSKEELIAELQDCEGLIVRSATKVTADVI 64
Query: 263 DAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPA 442
+A KL+VVGRAG GVDN+D+++A +KG+ V+N P N+LSA ELTC +++ LAR + A
Sbjct: 65 NAAEKLQVVGRAGTGVDNVDLEAATRKGILVMNTPNGNSLSAAELTCGMIMCLARQIPQA 124
Query: 443 STALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCA 622
+ ++K G+W+R + G+EL GKTL ILGLGR+GREVATRM +FGM IG+DP +S + A
Sbjct: 125 TASMKDGKWERKKFMGTELNGKTLGILGLGRIGREVATRMQSFGMKTIGYDPIISPEVSA 184
Query: 623 QFHCTKMELEDIWPLADYITLHTPLIXSTRNFIN 724
F ++ LE+IWPL D+IT+HTPL+ ST +N
Sbjct: 185 SFGVQQLPLEEIWPLCDFITVHTPLLPSTTGLLN 218
>UniRef50_Q0W4A2 Cluster: D-3-phosphoglycerate dehydrogenase; n=11;
cellular organisms|Rep: D-3-phosphoglycerate
dehydrogenase - Uncultured methanogenic archaeon RC-I
Length = 526
Score = 200 bits (489), Expect = 2e-50
Identities = 87/211 (41%), Positives = 149/211 (70%), Gaps = 1/211 (0%)
Frame = +2
Query: 95 VLIVDGVGAKCAELLNAY-GIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAG 271
VL+ D + + ++L + G+ + +++KE+L+ +I +++AL++RS TQVTKEV+ AG
Sbjct: 3 VLVTDPISEEGIKILKSEPGVQVDIETRLTKEQLIEKIKDYNALIIRSETQVTKEVIAAG 62
Query: 272 VKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTA 451
LK++GRAG G+DN+DV +A +KG+ V NAP N ++ACE T ++ML ++R++ A+ +
Sbjct: 63 KNLKIIGRAGVGIDNVDVPAATEKGIIVANAPEGNTIAACEHTLSMMLAMSRNIPQANAS 122
Query: 452 LKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFH 631
LK+G+W+R+ + G E+ KTL I+GLGR+G E+ R +FGM ++ +DPF +A++ Q
Sbjct: 123 LKSGKWERSKFMGVEVMNKTLGIIGLGRIGGEITKRARSFGMEVLAYDPFTTAERAQQIG 182
Query: 632 CTKMELEDIWPLADYITLHTPLIXSTRNFIN 724
L++I+ AD+IT+HTPL ST++ ++
Sbjct: 183 ARLTTLDEIYEKADFITVHTPLTPSTKHMVS 213
>UniRef50_Q3AQU0 Cluster: D-3-phosphoglycerate dehydrogenase; n=5;
Chlorobium/Pelodictyon group|Rep: D-3-phosphoglycerate
dehydrogenase - Chlorobium chlorochromatii (strain CaD3)
Length = 538
Score = 193 bits (471), Expect = 3e-48
Identities = 95/216 (43%), Positives = 137/216 (63%)
Frame = +2
Query: 83 DIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVL 262
++ VLI D V +C LL +G T K +S +EL I +++ L+VRSAT + EVL
Sbjct: 11 NVMKVLITDSVHPQCGRLLLQHGFEVTEKPSLSPKELHAIIADYNILIVRSATSLPAEVL 70
Query: 263 DAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPA 442
+L+++GRAG GVDNID+++A ++G+ V++ PG NA+SA E TC ++L ARH+ A
Sbjct: 71 AKATQLELIGRAGTGVDNIDLEAATRQGIVVMSTPGGNAVSAAEHTCAMLLAAARHIPQA 130
Query: 443 STALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCA 622
LK G W++ LY G EL GKTL+++GLGRVGREVA RM AFGM I +DP ++ + A
Sbjct: 131 MADLKQGNWNKHLYAGIELEGKTLSLIGLGRVGREVAMRMQAFGMRTIAYDPAIADEDAA 190
Query: 623 QFHCTKMELEDIWPLADYITLHTPLIXSTRNFINAD 730
+ L + AD IT+H+ L ST N + +
Sbjct: 191 LLDIELLPLHENLLRADVITIHSALDESTYNLLGKE 226
>UniRef50_Q58424 Cluster: D-3-phosphoglycerate dehydrogenase; n=7;
Euryarchaeota|Rep: D-3-phosphoglycerate dehydrogenase -
Methanococcus jannaschii
Length = 524
Score = 191 bits (466), Expect = 1e-47
Identities = 94/213 (44%), Positives = 139/213 (65%), Gaps = 1/213 (0%)
Frame = +2
Query: 95 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 274
+L+ D + ++L G ++KEELL +I + D LVVRS T+VT++V++
Sbjct: 4 ILVTDPLHEDAIKILEEVGEVEVATG-LTKEELLEKIKDADVLVVRSGTKVTRDVIEKAE 62
Query: 275 KLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL 454
KLKV+GRAG GVDNIDV++A +KG+ V+NAP A+++S ELT LML AR++ A+ +L
Sbjct: 63 KLKVIGRAGVGVDNIDVEAATEKGIIVVNAPDASSISVAELTMGLMLAAARNIPQATASL 122
Query: 455 KAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHC 634
K G WDR + G EL GKTL ++GLGR+G++V R AFGMNIIG+DP++ +
Sbjct: 123 KRGEWDRKRFKGIELYGKTLGVIGLGRIGQQVVKRAKAFGMNIIGYDPYIPKEVAESMGV 182
Query: 635 TKM-ELEDIWPLADYITLHTPLIXSTRNFINAD 730
+ ++ ++ AD+ITLH PL TR+ I +
Sbjct: 183 ELVDDINELCKRADFITLHVPLTPKTRHIIGRE 215
>UniRef50_A5UQ03 Cluster: D-3-phosphoglycerate dehydrogenase; n=5;
Chloroflexi (class)|Rep: D-3-phosphoglycerate
dehydrogenase - Roseiflexus sp. RS-1
Length = 524
Score = 191 bits (465), Expect = 2e-47
Identities = 88/187 (47%), Positives = 132/187 (70%)
Frame = +2
Query: 167 KAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKG 346
+ + K L+ +P +DAL+VRSAT+VT EVL AG +L+VVGRAG GVDNID+++A ++G
Sbjct: 27 RTDLDKAGLIAILPEYDALIVRSATRVTAEVLAAGTRLRVVGRAGTGVDNIDLEAATRQG 86
Query: 347 VGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILG 526
+ V+NAP +N+++ ELT L+L LARH+ A +++ AG+W+R + G E+ KTL ++G
Sbjct: 87 IMVVNAPASNSVAVAELTIALILSLARHIPQAHSSVVAGKWERNRFMGFEVRNKTLGLVG 146
Query: 527 LGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYITLHTPLIXS 706
LGR+G EVA R M+++ +DP VS ++ AQ T LE++ AD ++LH PLI +
Sbjct: 147 LGRIGAEVARRARGLEMHVVAYDPVVSTERAAQLGATLAPLEEVLAQADIVSLHVPLIDA 206
Query: 707 TRNFINA 727
TRN I+A
Sbjct: 207 TRNMIDA 213
>UniRef50_A0L7J1 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
Proteobacteria|Rep: D-3-phosphoglycerate dehydrogenase -
Magnetococcus sp. (strain MC-1)
Length = 527
Score = 190 bits (463), Expect = 3e-47
Identities = 88/214 (41%), Positives = 134/214 (62%), Gaps = 1/214 (0%)
Frame = +2
Query: 95 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 274
VLI D + E+ A G+ K +S +ELL I +D + +RSAT++ + + A
Sbjct: 4 VLIADKMSPMAEEVFRARGLEVDVKVGMSPDELLACIDQYDGIAIRSATRLPAQAIAAAS 63
Query: 275 KLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL 454
+LKV+GRAG GVDN+D +A +KG+ V+N P NA++ EL TL + ARH+ A+ +
Sbjct: 64 RLKVIGRAGIGVDNVDTPAASQKGIIVMNTPFGNAITTAELGVTLAMAAARHIPAATAST 123
Query: 455 KAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHC 634
KAG+W+++ + G ELAGKT ++GLG VGR VA R+ M ++ +DPF++ D+
Sbjct: 124 KAGKWEKSRFMGRELAGKTAGVIGLGNVGRLVAQRLAGLDMKVVAYDPFINKDRAISLGL 183
Query: 635 TKME-LEDIWPLADYITLHTPLIXSTRNFINADV 733
++ LED+WP D +T+HTPL TRN ++A V
Sbjct: 184 EMVDKLEDLWPRVDLLTVHTPLNDHTRNLVDAKV 217
>UniRef50_Q3ZX05 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
Dehalococcoides|Rep: D-3-phosphoglycerate dehydrogenase
- Dehalococcoides sp. (strain CBDB1)
Length = 526
Score = 190 bits (462), Expect = 4e-47
Identities = 94/212 (44%), Positives = 133/212 (62%)
Frame = +2
Query: 86 IKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLD 265
+K VL+ D + A L K + EEL+ I +DAL+VRS TQVT ++++
Sbjct: 1 MKKVLVSDALSATGLAPLKEIA-QVDVKTGLKPEELISIIGEYDALLVRSQTQVTADIIN 59
Query: 266 AGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPAS 445
AG KL+V+GRAG GVDNID+ +A G+ V+NAP N +SA E T LML +ARH+ A+
Sbjct: 60 AGKKLQVIGRAGVGVDNIDLKTATGNGIIVVNAPTGNTISATEHTLALMLAMARHIPRAN 119
Query: 446 TALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQ 625
+LK+G+W R + GSEL GKTL I+GLG +G E+A R A M +IG+DPF+S ++ +
Sbjct: 120 ASLKSGQWKRNEFVGSELKGKTLGIVGLGNIGSEIAKRALALEMRVIGYDPFISMERAKK 179
Query: 626 FHCTKMELEDIWPLADYITLHTPLIXSTRNFI 721
+ ED+ AD+ITLH P+ T+ I
Sbjct: 180 LQVELLPFEDLLKRADFITLHVPMTGQTKGLI 211
>UniRef50_A7HDB1 Cluster: D-3-phosphoglycerate dehydrogenase; n=5;
Proteobacteria|Rep: D-3-phosphoglycerate dehydrogenase -
Anaeromyxobacter sp. Fw109-5
Length = 528
Score = 190 bits (462), Expect = 4e-47
Identities = 80/214 (37%), Positives = 140/214 (65%)
Frame = +2
Query: 86 IKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLD 265
+ VL+ D + + +L G+ K + ++L + ++D L VRSAT+VT ++LD
Sbjct: 2 VARVLVSDDLSPEAVRILQEAGLEVDVKVGLKPDQLERIVGDYDGLAVRSATKVTAQLLD 61
Query: 266 AGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPAS 445
+LKV+GRAG GVDN+D+ +A ++GV V+N PG ++++ EL +++L L+RHV A+
Sbjct: 62 KAARLKVIGRAGVGVDNVDLAAATRRGVVVMNTPGGSSITVAELALSMILALSRHVAAAT 121
Query: 446 TALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQ 625
++KAG+W++ + G ELAG+TL ++G+G +G + R A GM ++ FDPF+SA+ A+
Sbjct: 122 GSVKAGKWEKKRFQGHELAGRTLGVVGIGNIGSVLVARAVALGMRVVAFDPFISAEAAAK 181
Query: 626 FHCTKMELEDIWPLADYITLHTPLIXSTRNFINA 727
+ ++L+ +W AD +++H PL TR+ ++A
Sbjct: 182 LGASLVDLDTLWREADVVSIHVPLTDKTRHLVDA 215
>UniRef50_Q897N8 Cluster: D-3-phosphoglycerate dehydrogenase; n=4;
Clostridiales|Rep: D-3-phosphoglycerate dehydrogenase -
Clostridium tetani
Length = 533
Score = 188 bits (459), Expect = 9e-47
Identities = 96/217 (44%), Positives = 137/217 (63%), Gaps = 2/217 (0%)
Frame = +2
Query: 80 VDIKSVLIVDGVGAKCAELLNAY-GIATTTKAKISKEELLMEIPNHDALVVRSATQVTKE 256
+D +LIVD + K ELL + K + +E+LL I N+D L++RS T + E
Sbjct: 1 MDKAKILIVDKIDTKGIELLESEPNFEVDIKMGLEREKLLNIIENYDGLIIRSDTNIDIE 60
Query: 257 VLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVV 436
+++ KLKVVGRAG GVDNID+ A K+G+ V N P +N +SACELT L+L +R++
Sbjct: 61 LMNMAKKLKVVGRAGNGVDNIDIPEATKRGIIVANTPDSNTISACELTIGLLLAQSRNIA 120
Query: 437 PASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQ 616
LK G WDR + G+EL KTL I+GLGR+G VATRM AF M +I +DP++S ++
Sbjct: 121 KTDRFLKEGNWDRDSFMGTELFNKTLGIIGLGRIGSLVATRMNAFDMKVIAYDPYISDER 180
Query: 617 CAQFHCTKME-LEDIWPLADYITLHTPLIXSTRNFIN 724
+F+ K + LED+ +D+IT+HTP T N I+
Sbjct: 181 FKRFNVEKKDTLEDLLKESDFITIHTPRTEETINIIS 217
>UniRef50_Q8PW48 Cluster: D-3-phosphoglycerate dehydrogenase; n=4;
Methanomicrobia|Rep: D-3-phosphoglycerate dehydrogenase
- Methanosarcina mazei (Methanosarcina frisia)
Length = 540
Score = 186 bits (452), Expect = 7e-46
Identities = 91/215 (42%), Positives = 139/215 (64%)
Frame = +2
Query: 80 VDIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEV 259
+D+K VL+ D + + E+L + + ++EL+ +I +DALV+RS TQVT+ +
Sbjct: 16 IDMK-VLVSDSLSNEGLEILKEH-FDIDVCTGLCEDELVEKIKGYDALVIRSGTQVTQRI 73
Query: 260 LDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVP 439
++A LK++GRAG GVDN+DVD+A KKG+ V NAP N +SA E T +M+ ++R++
Sbjct: 74 IEAADNLKIIGRAGVGVDNVDVDAATKKGIIVANAPEGNMISAAEHTIAMMMSMSRNIPQ 133
Query: 440 ASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQC 619
A+ +LKA W R + G E+ GKTL ++GLGR+G EVA R MN++G+DPF+S +
Sbjct: 134 ANASLKAREWKRNKFMGVEVKGKTLGVIGLGRIGSEVAKRAAGLEMNLMGYDPFISEKRA 193
Query: 620 AQFHCTKMELEDIWPLADYITLHTPLIXSTRNFIN 724
+ + +I ADYIT+HTPLI TRN ++
Sbjct: 194 MELGVKLATVNEIAKEADYITVHTPLIKETRNILD 228
>UniRef50_A2U4T1 Cluster: D-3-phosphoglycerate dehydrogenase; n=14;
Bacillales|Rep: D-3-phosphoglycerate dehydrogenase -
Bacillus coagulans 36D1
Length = 541
Score = 184 bits (449), Expect = 2e-45
Identities = 89/212 (41%), Positives = 140/212 (66%), Gaps = 1/212 (0%)
Frame = +2
Query: 92 SVLIVDGVGAKCAELLNAY-GIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDA 268
++L+ D V + + L A+ + I+ E+L I +D L+VR+ T+VTK++++A
Sbjct: 3 NILVTDKVSEEGLKKLYAHKDFIVEHQPGIAPEDLKATIGQYDGLIVRNQTKVTKDIIEA 62
Query: 269 GVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPAST 448
L+V+ RAG GVDNIDVD+A +KG+ V+N+PG N +SA E T +ML L+R++ A
Sbjct: 63 SGNLRVIARAGVGVDNIDVDAATRKGIIVVNSPGGNTISATEHTLAMMLSLSRNIPQAHK 122
Query: 449 ALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQF 628
+ AG+W+R + G EL KTL I+G G++G EVA R AFGM ++G+DP+++ ++ A+
Sbjct: 123 SAAAGKWEREKFKGVELFKKTLGIIGTGKIGTEVAKRAKAFGMAVLGYDPYLTEERAAKL 182
Query: 629 HCTKMELEDIWPLADYITLHTPLIXSTRNFIN 724
K L++I AD+ITLHTPL+ T++ IN
Sbjct: 183 GIKKATLDEIAAQADFITLHTPLMKETKHLIN 214
>UniRef50_A6UQN3 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Methanococcus|Rep: D-3-phosphoglycerate dehydrogenase -
Methanococcus vannielii SB
Length = 523
Score = 182 bits (443), Expect = 8e-45
Identities = 90/209 (43%), Positives = 134/209 (64%)
Frame = +2
Query: 95 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 274
+LI D + E+L G IS EE+ +I + DALVVRS T VTKE++DA
Sbjct: 4 ILITDPLHESAIEILKEAGEVEIATG-ISIEEIKQKIKDADALVVRSGTTVTKEIIDASE 62
Query: 275 KLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL 454
LKV+ RAG GVDN+D+D+A +KGV V+NAP A+++S EL LML AR++ A+ +L
Sbjct: 63 NLKVIARAGVGVDNVDLDAATEKGVVVVNAPDASSISVAELMFGLMLSAARNIPQATASL 122
Query: 455 KAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHC 634
K G WDR + G E+ KTL I+GLGR+G++VA R AF MNI+ +DP++ + ++
Sbjct: 123 KKGEWDRKSFKGMEVYAKTLGIVGLGRIGQQVAKRAQAFEMNIVAYDPYIPENVASELGI 182
Query: 635 TKMELEDIWPLADYITLHTPLIXSTRNFI 721
+ ++++ +++ITLH PL T++ I
Sbjct: 183 KLLSVDELCAESEFITLHVPLTTKTKHMI 211
>UniRef50_O29445 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
cellular organisms|Rep: D-3-phosphoglycerate
dehydrogenase - Archaeoglobus fulgidus
Length = 527
Score = 182 bits (443), Expect = 8e-45
Identities = 84/209 (40%), Positives = 129/209 (61%)
Frame = +2
Query: 95 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 274
VL+ + + + + + G+ K +S+EEL+ E+P ++A+VVRS T+V EV+ A
Sbjct: 3 VLVAEPISEEAIDYMRKNGLEVEVKTGMSREELIREVPKYEAIVVRSQTKVDAEVIQAAK 62
Query: 275 KLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL 454
LK++GRAG GVDNID+++A ++G+ V+NAPG N +S E LML AR + A ++
Sbjct: 63 NLKIIGRAGVGVDNIDINAATQRGIVVVNAPGGNTISTAEHAIALMLAAARKIPQADRSV 122
Query: 455 KAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHC 634
K G+W+R + G EL GKT ++GLGRVG EVA R A MN++ +DPFVS ++ Q
Sbjct: 123 KEGKWERKKFMGIELRGKTAGVIGLGRVGFEVAKRCKALEMNVLAYDPFVSKERAEQIGV 182
Query: 635 TKMELEDIWPLADYITLHTPLIXSTRNFI 721
++ + + +D IT+H P T I
Sbjct: 183 KLVDFDTLLASSDVITVHVPRTKETIGLI 211
>UniRef50_P73821 Cluster: D-3-phosphoglycerate dehydrogenase; n=37;
Cyanobacteria|Rep: D-3-phosphoglycerate dehydrogenase -
Synechocystis sp. (strain PCC 6803)
Length = 554
Score = 182 bits (442), Expect = 1e-44
Identities = 82/212 (38%), Positives = 139/212 (65%)
Frame = +2
Query: 95 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 274
VL+ D + ++L K +S+ E++ +P +DA+++RSAT+VT++++ AG
Sbjct: 32 VLVSDSIDQVGIDILKQVA-QVDVKTGLSEAEIIDIVPEYDAIMLRSATKVTEKIIQAGS 90
Query: 275 KLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL 454
+LK++GRAG GVDNIDV +A ++G+ V+N+P N ++A E +M+ LARH+ A+ ++
Sbjct: 91 QLKIIGRAGVGVDNIDVPAATRQGIVVVNSPEGNTIAAAEHALAMMMALARHIPDANKSV 150
Query: 455 KAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHC 634
K +W+R + G+E+ KTL ++GLG++G VA A GM ++ +DPF+S ++ Q C
Sbjct: 151 KESKWERKQFIGTEVYKKTLGVVGLGKIGSHVAGVAKAMGMKLLAYDPFISQERADQIGC 210
Query: 635 TKMELEDIWPLADYITLHTPLIXSTRNFINAD 730
T ++L+ ++ AD+ITLH P T N INA+
Sbjct: 211 TLVDLDLLFSEADFITLHIPKTPETANLINAE 242
>UniRef50_Q2AHU0 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Halothermothrix orenii H 168|Rep: D-3-phosphoglycerate
dehydrogenase - Halothermothrix orenii H 168
Length = 527
Score = 181 bits (441), Expect = 1e-44
Identities = 91/210 (43%), Positives = 128/210 (60%)
Frame = +2
Query: 95 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 274
VL+ D + K E+L T +S+EE L I +D L+VRS T+V KE LD
Sbjct: 4 VLVSDNISPKGIEILEQEA-DVTFNPDLSREEFLDIIGEYDGLIVRSMTEVDKEALDKAR 62
Query: 275 KLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL 454
LKV+GRAG G DNID++ A K+G+ V N P N +SA E T +ML L+R++ A+ AL
Sbjct: 63 NLKVIGRAGTGYDNIDIEEASKRGIIVFNTPTGNTISAVEHTIGMMLALSRNIPQANQAL 122
Query: 455 KAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHC 634
G WDR Y G E+ GKTL I+GLGR+G VA R AFGM +I DP++ ++ A+ +
Sbjct: 123 HEGIWDRKKYMGVEVKGKTLGIIGLGRIGSRVAVRAQAFGMKVIANDPYLPPEKAAKINV 182
Query: 635 TKMELEDIWPLADYITLHTPLIXSTRNFIN 724
+ +++ +DYITLHTPL T + ++
Sbjct: 183 PLLGFKEVLKKSDYITLHTPLTDETYHILS 212
>UniRef50_UPI0000DC0E13 Cluster: 3-phosphoglycerate dehydrogenase;
n=4; Amniota|Rep: 3-phosphoglycerate dehydrogenase -
Rattus norvegicus
Length = 316
Score = 181 bits (440), Expect = 2e-44
Identities = 92/214 (42%), Positives = 136/214 (63%)
Frame = +2
Query: 83 DIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVL 262
++ VLI D + C +LL G+ K +SKEEL++EI + + T+VT +V
Sbjct: 5 NLHKVLISDILDPGCWKLLKDGGLQVVEKQNLSKEELIVEIQDCET------TKVTADVT 58
Query: 263 DAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPA 442
+ KL++VGRAG G+DN+++++A K + V+N P +LSA ELTC +++ L R + P
Sbjct: 59 NTAEKLQLVGRAGTGMDNVNLEAAMTKSILVMNTPNGKSLSASELTCGMIVCLTRQIPP- 117
Query: 443 STALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCA 622
G+WD+ + G+EL GKTL ILGLGR+GREV T+M AF M +GFDP S + A
Sbjct: 118 ------GKWDQEEFMGTELNGKTLGILGLGRIGREVTTQMQAFRMKAVGFDPISSPEIAA 171
Query: 623 QFHCTKMELEDIWPLADYITLHTPLIXSTRNFIN 724
F ++ LE++WPL D+IT+HTPL+ ST +N
Sbjct: 172 SFGVQQLLLEELWPLCDFITVHTPLLLSTTGLLN 205
>UniRef50_Q9X1C1 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
Thermotogaceae|Rep: D-3-phosphoglycerate dehydrogenase -
Thermotoga maritima
Length = 306
Score = 180 bits (438), Expect = 3e-44
Identities = 91/212 (42%), Positives = 131/212 (61%)
Frame = +2
Query: 95 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 274
V + D + + +LL T + K+EL+ IP D LVVRSAT+VT ++++AG
Sbjct: 6 VHVNDPLDKEATQLLMNKEELEVTSEHLEKDELMKIIPEVDVLVVRSATKVTADIIEAGK 65
Query: 275 KLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL 454
LK++ RAG G+DNIDV A +KG+ V+N PGA+A S EL LML ARH+ A+ +L
Sbjct: 66 NLKIIARAGIGLDNIDVQKAKEKGIKVLNTPGASAPSVAELAMGLMLACARHIARATVSL 125
Query: 455 KAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHC 634
K G+W++ G EL GKTL ++G G +G+EVA R AFGM II +DP A
Sbjct: 126 KEGKWEKKALKGKELLGKTLGLIGFGNIGQEVAKRALAFGMKIIAYDP---AKPETDLPV 182
Query: 635 TKMELEDIWPLADYITLHTPLIXSTRNFINAD 730
++L+ ++ +D+I+LH PL STR+ IN +
Sbjct: 183 EYVDLDTLFKESDFISLHVPLTESTRHIINRE 214
>UniRef50_A1SM51 Cluster: D-3-phosphoglycerate dehydrogenase; n=15;
Actinobacteria (class)|Rep: D-3-phosphoglycerate
dehydrogenase - Nocardioides sp. (strain BAA-499 /
JS614)
Length = 536
Score = 179 bits (436), Expect = 6e-44
Identities = 89/181 (49%), Positives = 120/181 (66%)
Frame = +2
Query: 188 ELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAP 367
ELL +P DA++VRSAT+V E L A +LKV+ RAG G+DN+DV +A + GV V+NAP
Sbjct: 44 ELLAALPEADAILVRSATKVDAEALAAARRLKVIARAGVGLDNVDVRAATQAGVMVVNAP 103
Query: 368 GANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGRE 547
+N +SA EL LML ARH+ PA ALK G W RA YTG+EL KT+ I+GLGR+G
Sbjct: 104 TSNIVSAAELAVALMLAAARHISPAHAALKNGEWKRARYTGTELYEKTVGIVGLGRIGVL 163
Query: 548 VATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYITLHTPLIXSTRNFINA 727
VA R+ AFGM I+ +DP+V A + AQ ++L+ + AD++++H P T I A
Sbjct: 164 VAQRLSAFGMKIVAYDPYVQAGRAAQMGVRLVDLDTLLAEADFMSVHLPKTPETVGLIGA 223
Query: 728 D 730
D
Sbjct: 224 D 224
>UniRef50_Q1NQ97 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding; n=2;
Bacteria|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding - delta
proteobacterium MLMS-1
Length = 304
Score = 179 bits (435), Expect = 8e-44
Identities = 84/212 (39%), Positives = 133/212 (62%)
Frame = +2
Query: 95 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 274
VLI D + +++ G+ + +S EEL+ IP +D LV+RSA++VT E+L+A
Sbjct: 3 VLISDNLAPVGEKIMRDAGLEVDVRTGLSPEELVKIIPAYDGLVIRSASKVTAEILEAAE 62
Query: 275 KLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL 454
LKVVGRAG G+DN+DV +A KKGV V+NAP NA +A E ++M+ L R++ A+ ++
Sbjct: 63 NLKVVGRAGIGLDNVDVPAASKKGVVVMNAPDGNATTAAEHAVSMMMALTRNIPQATASM 122
Query: 455 KAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHC 634
KAG+W++ + G E+ K ++G+GR+GR A R M +I FDP + A+Q +
Sbjct: 123 KAGKWEKKKFQGHEVTAKVAGVVGIGRIGRIFAERAMGLRMKVIAFDPHMPAEQMEKIGV 182
Query: 635 TKMELEDIWPLADYITLHTPLIXSTRNFINAD 730
+ LE++ ADYI++H PL T++ + A+
Sbjct: 183 EPVTLEELCQRADYISVHVPLTPETKHVLGAE 214
>UniRef50_A3EWA5 Cluster: Phosphoglycerate dehydrogenase; n=2;
Bacteria|Rep: Phosphoglycerate dehydrogenase -
Leptospirillum sp. Group II UBA
Length = 535
Score = 179 bits (435), Expect = 8e-44
Identities = 84/217 (38%), Positives = 137/217 (63%)
Frame = +2
Query: 74 MVVDIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTK 253
M DI+ +LI D + + G K K+S +EL EI +D LV+RS T+VT+
Sbjct: 1 MSSDIR-ILISDAISEDGVRIFQKAGFHVDMKTKLSPQELAQEISQYDGLVIRSGTKVTR 59
Query: 254 EVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHV 433
E+L +LKV+GRAGAG+DN+D+++A ++G+ V+N PG N ++ E T +L++ +AR +
Sbjct: 60 EILKNADRLKVIGRAGAGLDNVDLEAATERGIVVMNTPGGNTVTTAEHTMSLLMSMARRI 119
Query: 434 VPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSAD 613
A+ + KAG+W+++ + G EL KTL I+G+G++G+ VA MNII FDP+++ +
Sbjct: 120 PQANASNKAGKWEKSKFMGVELFQKTLGIVGMGKIGQHVAQIARGIAMNIIAFDPYLTPE 179
Query: 614 QCAQFHCTKMELEDIWPLADYITLHTPLIXSTRNFIN 724
+ + L++++ AD+IT+HTPL T IN
Sbjct: 180 VAEKSGVHPVSLDELFQRADFITVHTPLTPETTGLIN 216
>UniRef50_Q8YIU3 Cluster: D-3-PHOSPHOGLYCERATE DEHYDROGENASE; n=75;
Bacteria|Rep: D-3-PHOSPHOGLYCERATE DEHYDROGENASE -
Brucella melitensis
Length = 538
Score = 177 bits (432), Expect = 2e-43
Identities = 86/213 (40%), Positives = 133/213 (62%), Gaps = 2/213 (0%)
Frame = +2
Query: 95 VLIVDGVGAKCAELLNAYGIATTTKAKISK--EELLMEIPNHDALVVRSATQVTKEVLDA 268
VL+ D + ++ G+ + K E+LL I +D L +RSAT+VT++++ A
Sbjct: 10 VLVSDKLSPTAVQIFKDRGVDVDYLPDLGKDKEKLLEVIGEYDGLAIRSATKVTEKLIAA 69
Query: 269 GVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPAST 448
KLKVVGRAG GVDN+D+ +A ++G+ V+N P N+++ E LM +AR + A T
Sbjct: 70 AKKLKVVGRAGIGVDNVDIPAASRRGIIVMNTPFGNSITTAEHAIALMFAVARQLPEADT 129
Query: 449 ALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQF 628
+ +AG+W++ + G E+ GKTL ++G G +G VATR M+++ FDPF+S + +
Sbjct: 130 STRAGKWEKNRFMGVEITGKTLGVVGCGNIGSIVATRGIGLKMHVVAFDPFLSDARAQEL 189
Query: 629 HCTKMELEDIWPLADYITLHTPLIXSTRNFINA 727
K+EL+++ AD+ITLHTPLI TRN INA
Sbjct: 190 GVEKVELDELLARADFITLHTPLIDKTRNIINA 222
>UniRef50_Q7UQL2 Cluster: Phosphoglycerate dehydrogenase; n=2;
Planctomycetaceae|Rep: Phosphoglycerate dehydrogenase -
Rhodopirellula baltica
Length = 540
Score = 177 bits (430), Expect = 3e-43
Identities = 82/214 (38%), Positives = 133/214 (62%), Gaps = 2/214 (0%)
Frame = +2
Query: 95 VLIVDGVGAKCAELLNAY-GIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAG 271
+L++D + + +LL A GI + K+ EEL + DA ++RS +T E L+
Sbjct: 4 ILVLDDIAQEGIDLLEASEGIEYEVRTKLKGEELRQSLNEFDAAILRSGVTITPESLEGN 63
Query: 272 VKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTA 451
+L+ + RAG G DNID +A ++G+ V+N P N +S E T ++L ++R++ A+ +
Sbjct: 64 TRLRALVRAGVGTDNIDKPAATRRGIVVMNTPAGNTVSTAEHTFAMLLAMSRNIAAANQS 123
Query: 452 LKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFH 631
L GRWDR + G+++AGKTL I+G+GR+GREVA+R AF M+++ FDPF++ DQ
Sbjct: 124 LVEGRWDRKKFMGTQVAGKTLGIVGMGRIGREVASRAQAFDMDVVAFDPFLTDDQAESLK 183
Query: 632 CTKM-ELEDIWPLADYITLHTPLIXSTRNFINAD 730
++ ++D+ P DY+T+HTPL TR I +
Sbjct: 184 VRRVATVDDMLPQIDYLTVHTPLTPETRGLIGME 217
>UniRef50_Q1PZY1 Cluster: Similar to D-3-phosphoglycerate
dehydrogenase; n=1; Candidatus Kuenenia
stuttgartiensis|Rep: Similar to D-3-phosphoglycerate
dehydrogenase - Candidatus Kuenenia stuttgartiensis
Length = 535
Score = 174 bits (423), Expect = 2e-42
Identities = 91/213 (42%), Positives = 127/213 (59%), Gaps = 2/213 (0%)
Frame = +2
Query: 95 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 274
VLI D + C E+L G+ K + EL I D ++VRS T++T VL+
Sbjct: 12 VLIADDLPDVCNEILQNAGVEVLKKTGLKPPELDAVIKMCDGVIVRSNTKLTAPVLEKSE 71
Query: 275 KLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL 454
KLK + RAG GVDNIDV +A KKG+ V+N P N +S E T L+ L+R V A ++
Sbjct: 72 KLKAICRAGVGVDNIDVPAATKKGIVVMNTPAGNIISTAEHTIALLCSLSRFVPQACASV 131
Query: 455 KAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQF-- 628
K G+W++ +TG +L GKT I+GLGRVGR+VA R A M +IG+DPF++ + +Q+
Sbjct: 132 KEGKWEKKKFTGQQLTGKTFGIIGLGRVGRQVAKRAAALEMKVIGYDPFITTEISSQYNI 191
Query: 629 HCTKMELEDIWPLADYITLHTPLIXSTRNFINA 727
H K L D+ ADYIT+H L T+N I +
Sbjct: 192 HIVK-NLRDLLAQADYITIHVTLNKETKNLITS 223
>UniRef50_A6C9V4 Cluster: Phosphoglycerate dehydrogenase; n=1;
Planctomyces maris DSM 8797|Rep: Phosphoglycerate
dehydrogenase - Planctomyces maris DSM 8797
Length = 541
Score = 174 bits (423), Expect = 2e-42
Identities = 87/214 (40%), Positives = 136/214 (63%), Gaps = 2/214 (0%)
Frame = +2
Query: 95 VLIVDGVGAKCAELLNAYG-IATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAG 271
VLI D + ++L I ++ +S EE+ + + D +++RSAT++T+EVL
Sbjct: 4 VLITDNLSPAGLKILEDNPEIEVDIRSGLSPEEVREALKSADGIIIRSATKLTEEVLKGQ 63
Query: 272 VKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTA 451
+LK + RAG GVDNID +A ++G+ V+N P N S E T LM+ LAR++ PA
Sbjct: 64 PRLKAIVRAGVGVDNIDRAAATREGIVVMNTPAGNTTSTAEQTIALMMALARNIGPAYAT 123
Query: 452 LKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFH 631
+K G+W+R TG+++AGKTLAI+GLGR+G VA R M +IG+DPF+SA++ A++
Sbjct: 124 MKEGKWERKKLTGTQVAGKTLAIIGLGRIGLSVAHRAQGLEMKVIGYDPFMSAERAAEYG 183
Query: 632 C-TKMELEDIWPLADYITLHTPLIXSTRNFINAD 730
E++++ D++T+HTPL TR+ INA+
Sbjct: 184 IELYKEVDELVKHCDFLTVHTPLTDETRDLINAE 217
>UniRef50_Q67TJ9 Cluster: Phosphoglycerate dehydrogenase; n=1;
Symbiobacterium thermophilum|Rep: Phosphoglycerate
dehydrogenase - Symbiobacterium thermophilum
Length = 540
Score = 173 bits (421), Expect = 4e-42
Identities = 88/187 (47%), Positives = 119/187 (63%), Gaps = 2/187 (1%)
Frame = +2
Query: 173 KISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVG 352
K++ EELL IP +DAL+ RS T+VT EVL G +LKVVGRAG GVDNIDV +A ++GV
Sbjct: 27 KVTSEELLEIIPEYDALITRSETKVTAEVLARGTRLKVVGRAGVGVDNIDVAAATERGVV 86
Query: 353 VINAPGANALSACELTCTLMLVLARHVVPASTAL-KAGRWDRALYTGSELAGKTLAILGL 529
V+N PGAN S E L++ +AR++ A AL + GRWDR + G+EL GKTL I+GL
Sbjct: 87 VVNVPGANTYSTAEHAFGLLIAVARNIPQAHHALAREGRWDRMSFVGTELHGKTLGIIGL 146
Query: 530 GRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKM-ELEDIWPLADYITLHTPLIXS 706
GR+G EVA R AFGM ++ +DP+V + T + L + P D++T+H
Sbjct: 147 GRIGSEVAVRARAFGMRVLAYDPYVPHSRAEHLGVTLVPSLRGLLPEVDFLTIHAAKTPE 206
Query: 707 TRNFINA 727
+ I A
Sbjct: 207 SARLIGA 213
>UniRef50_Q4L766 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
Staphylococcus|Rep: D-3-phosphoglycerate dehydrogenase -
Staphylococcus haemolyticus (strain JCSC1435)
Length = 532
Score = 172 bits (419), Expect = 7e-42
Identities = 83/214 (38%), Positives = 133/214 (62%), Gaps = 1/214 (0%)
Frame = +2
Query: 92 SVLIVDGVGAKCAE-LLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDA 268
++L+ D + + LLN K + ++ LL I +++ L+VRS TQVT++V++
Sbjct: 4 NILVSDPISTDGLQSLLNHSDFNVDIKTDLDEQSLLDIIGDYEGLIVRSQTQVTQQVIEK 63
Query: 269 GVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPAST 448
LKV+ RAG GVDNID+D+A +G+ VINAP N +SA E + ++L +AR++ A
Sbjct: 64 ASNLKVIARAGVGVDNIDIDAATLQGILVINAPDGNTISATEHSVAMILAMARNIPQAHA 123
Query: 449 ALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQF 628
+LK W+R + G EL KTL ++G GR+G VA R+ +FGM ++ +DP+++ D+ Q
Sbjct: 124 SLKNKEWNRKAFKGVELYQKTLGVIGAGRIGIGVAQRLQSFGMKVLAYDPYLTEDKAQQL 183
Query: 629 HCTKMELEDIWPLADYITLHTPLIXSTRNFINAD 730
+++I AD++T+HTPL TR +NAD
Sbjct: 184 GVKLATIDEIARQADFVTVHTPLTPKTRGIVNAD 217
>UniRef50_P35136 Cluster: D-3-phosphoglycerate dehydrogenase; n=8;
Bacillaceae|Rep: D-3-phosphoglycerate dehydrogenase -
Bacillus subtilis
Length = 525
Score = 172 bits (419), Expect = 7e-42
Identities = 82/177 (46%), Positives = 115/177 (64%)
Frame = +2
Query: 200 EIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANA 379
E+ DAL+VRSAT+VT+++ + LK+VGRAG GVDNID+D A K GV VINAP N
Sbjct: 37 ELHTFDALLVRSATKVTEDLFNKMTSLKIVGRAGVGVDNIDIDEATKHGVIVINAPNGNT 96
Query: 380 LSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATR 559
+S E T ++ L RH+ A+ ++K+ W+R Y GSEL GKTL I+GLGR+G E+A R
Sbjct: 97 ISTAEHTFAMISSLMRHIPQANISVKSREWNRTAYVGSELYGKTLGIVGLGRIGSEIAQR 156
Query: 560 MYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYITLHTPLIXSTRNFINAD 730
AFGM + FDPF++ ++ + E++ AD IT+HTPL T+ +N +
Sbjct: 157 RGAFGMTVHVFDPFLTEERAKKIGVNSRTFEEVLESADIITVHTPLTKETKGLLNKE 213
>UniRef50_Q8EN61 Cluster: Phosphoglycerate dehydrogenase; n=2;
Bacillaceae|Rep: Phosphoglycerate dehydrogenase -
Oceanobacillus iheyensis
Length = 528
Score = 171 bits (416), Expect = 2e-41
Identities = 89/213 (41%), Positives = 131/213 (61%), Gaps = 1/213 (0%)
Frame = +2
Query: 95 VLIVDGVGAKCAE-LLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAG 271
VLI D + + + L A I +++EL +I + DA++VRS TQVT+ +++
Sbjct: 5 VLISDPLSEEGLKPLQEAENIEVVINPGWNEQELSDQIDSFDAILVRSQTQVTRALIEKA 64
Query: 272 VKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTA 451
LK++GRAG GVDNID+++A + GV V+NAP N SA E T +++ L+R++ A A
Sbjct: 65 SNLKIIGRAGVGVDNIDLEAATENGVIVVNAPNGNTNSAAEHTMAMIMALSRNIPQAYHA 124
Query: 452 LKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFH 631
LK +WDR + G EL KTL I+GLGR+G EVA R MN+I +DPF + ++ Q
Sbjct: 125 LKQKQWDRKRFVGVELKQKTLGIVGLGRIGAEVAARAKGQRMNVIAYDPFFTEEKAEQMG 184
Query: 632 CTKMELEDIWPLADYITLHTPLIXSTRNFINAD 730
LED+ D+IT+HTPL+ T++ IN D
Sbjct: 185 VQYGTLEDVLRAGDFITVHTPLLKETKHLINKD 217
>UniRef50_A0LMX1 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Syntrophobacter fumaroxidans MPOB|Rep:
D-3-phosphoglycerate dehydrogenase - Syntrophobacter
fumaroxidans (strain DSM 10017 / MPOB)
Length = 525
Score = 171 bits (416), Expect = 2e-41
Identities = 84/213 (39%), Positives = 133/213 (62%), Gaps = 1/213 (0%)
Frame = +2
Query: 95 VLIVDGVGAKCAELLNAY-GIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAG 271
VLI DG+ +L A GI + EE+ +P++DA++VRS T++T E+++
Sbjct: 3 VLICDGMHEVGLSILRAAEGIDVDVPDQPGAEEIKAMLPDYDAVIVRSRTRITAELIENA 62
Query: 272 VKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTA 451
+LKV+GRAG GVDNIDV +A +G V+N PGANA +A E T +ML LARH+ A+ +
Sbjct: 63 PRLKVIGRAGTGVDNIDVKAASARGALVMNTPGANATAAAEHTIAMMLALARHIPQATQS 122
Query: 452 LKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFH 631
++ GRWD+ + G+EL +TL I+GLG++G VA R + M+++G DP++ + A
Sbjct: 123 MREGRWDKKRFMGTELFHQTLGIIGLGKIGSIVADRALSMKMDVLGHDPYIIPEAAAILG 182
Query: 632 CTKMELEDIWPLADYITLHTPLIXSTRNFINAD 730
+ L+++ +D++TLHTP T +N +
Sbjct: 183 VEWVPLDELLARSDFLTLHTPSTSETVRILNRE 215
>UniRef50_Q8R716 Cluster: Phosphoglycerate dehydrogenase and related
dehydrogenases; n=5; Clostridia|Rep: Phosphoglycerate
dehydrogenase and related dehydrogenases -
Thermoanaerobacter tengcongensis
Length = 533
Score = 170 bits (414), Expect = 3e-41
Identities = 83/209 (39%), Positives = 134/209 (64%)
Frame = +2
Query: 95 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 274
+++ + + + L Y K IS+EELL I ++DA++VRSAT+V +E+++ G
Sbjct: 3 IIVTEKISENGIDYLKKYA-DVDVKTNISREELLEVIKDYDAIIVRSATKVDRELIEKGE 61
Query: 275 KLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL 454
KLKV+GRAG GVDNIDV++A ++G+ V+N P N ++A ELT LML +AR++ A A
Sbjct: 62 KLKVIGRAGNGVDNIDVEAATQRGILVVNTPAGNTIAAAELTIGLMLAIARNIPQAYHAA 121
Query: 455 KAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHC 634
G + R + G EL GKT+ I+GLGR+G VA+R+ AF M +I +DP++ ++ +
Sbjct: 122 LNGDFRRDRFKGVELNGKTVGIIGLGRIGSLVASRLAAFNMRVIAYDPYMPDERFEKCGV 181
Query: 635 TKMELEDIWPLADYITLHTPLIXSTRNFI 721
++ L+++ +D+IT+H P T+ I
Sbjct: 182 KRVTLDELLEQSDFITIHIPKTEETKKMI 210
>UniRef50_UPI0000E4762C Cluster: PREDICTED: similar to
D-3-phosphoglycerate dehydrogenase; n=1;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
D-3-phosphoglycerate dehydrogenase - Strongylocentrotus
purpuratus
Length = 493
Score = 143 bits (347), Expect(2) = 3e-41
Identities = 68/135 (50%), Positives = 86/135 (63%)
Frame = +2
Query: 317 IDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSE 496
IDV + G PG N LSA E TC ++ L+R + A LKAG+WDR + GSE
Sbjct: 46 IDVYDYLRMAWGSTYTPGGNTLSAAEHTCAMVCCLSRSLPQAHATLKAGKWDRKAFMGSE 105
Query: 497 LAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADY 676
L GKTL I+GLGR+GREVA RM +FGM IGFDP V A++ Q++ LE +WP DY
Sbjct: 106 LYGKTLGIVGLGRIGREVAQRMQSFGMTTIGFDPIVPAEEAKQYNIEWQTLEQMWPRCDY 165
Query: 677 ITLHTPLIXSTRNFI 721
IT+HTPLI T+ +
Sbjct: 166 ITVHTPLIPQTKGLL 180
Score = 48.4 bits (110), Expect(2) = 3e-41
Identities = 23/45 (51%), Positives = 27/45 (60%)
Frame = +2
Query: 74 MVVDIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIP 208
M +K VLI D V +CAE+L GI K+SKEELL EIP
Sbjct: 1 MAFSLKKVLISDSVSPRCAEILRENGIEVDNNTKLSKEELLAEIP 45
>UniRef50_Q1IVI0 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Acidobacteria|Rep: D-3-phosphoglycerate dehydrogenase -
Acidobacteria bacterium (strain Ellin345)
Length = 531
Score = 170 bits (413), Expect = 3e-41
Identities = 83/182 (45%), Positives = 119/182 (65%)
Frame = +2
Query: 182 KEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVIN 361
KE+LL ++ DAL+VRSA V +L+ +L+V+GRAG GVDNI++++A +KG+ V+N
Sbjct: 34 KEQLLEQLKGADALIVRSAVFVDAAMLEHADQLRVIGRAGVGVDNIELEAATRKGIAVMN 93
Query: 362 APGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVG 541
PGANA++ E T LML LAR + A+ + AG+W++ G+EL GKTL I+GLGR+G
Sbjct: 94 TPGANAIAVAEHTIGLMLALARFIPRATETMHAGKWEKKSLQGTELRGKTLGIVGLGRIG 153
Query: 542 REVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYITLHTPLIXSTRNFI 721
EVA R +FGM ++ DP+VS + +++ +ADYITLH L T N I
Sbjct: 154 LEVARRAASFGMTLVAHDPYVSPAIAHDAKIRLADRDEVLAVADYITLHVGLTPQTANMI 213
Query: 722 NA 727
NA
Sbjct: 214 NA 215
>UniRef50_A1DFM4 Cluster: D-3-phosphoglycerate dehydrogenase; n=10;
Fungi/Metazoa group|Rep: D-3-phosphoglycerate
dehydrogenase - Neosartorya fischeri (strain ATCC 1020 /
DSM 3700 / NRRL 181)(Aspergillus fischerianus (strain
ATCC 1020 / DSM 3700 / NRRL 181))
Length = 582
Score = 169 bits (410), Expect = 8e-41
Identities = 87/211 (41%), Positives = 131/211 (62%), Gaps = 1/211 (0%)
Frame = +2
Query: 95 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 274
VL+ + + LL A + + + +ELL IP ++ALVVRS T+VT +L A
Sbjct: 11 VLVPEKLSPDGLALLRA-SLEVDERRGLDADELLQIIPEYEALVVRSETKVTGNLLRAAK 69
Query: 275 KLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL 454
+LKVV RAG GVDN+DV+ A K G+ V+N+P N +A E T L++ +AR++ A ++L
Sbjct: 70 QLKVVARAGVGVDNVDVEEATKLGIVVVNSPSGNIGAAAEHTIALLIAMARNIPEACSSL 129
Query: 455 KAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHC 634
K+G+W+R+ + G E+ GKTL+I+GLG+VG VA GMN+ DP+ S
Sbjct: 130 KSGKWERSKFVGVEVKGKTLSIIGLGKVGLTVARLAKGLGMNVNALDPYASPAVAVSASV 189
Query: 635 TKM-ELEDIWPLADYITLHTPLIXSTRNFIN 724
T + L ++ P AD++T+HTPLI ST+ I+
Sbjct: 190 TLVSSLSELLPTADFLTIHTPLIASTKGMIS 220
>UniRef50_O04130 Cluster: D-3-phosphoglycerate dehydrogenase,
chloroplast precursor; n=13; Magnoliophyta|Rep:
D-3-phosphoglycerate dehydrogenase, chloroplast
precursor - Arabidopsis thaliana (Mouse-ear cress)
Length = 624
Score = 168 bits (408), Expect = 1e-40
Identities = 83/211 (39%), Positives = 127/211 (60%), Gaps = 1/211 (0%)
Frame = +2
Query: 95 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 274
+L+ + +G LL +G + +S E+L ++ DAL+VRS T+VT+EV +A
Sbjct: 85 ILVTEKLGEAGVNLLREFGDVDCSY-DLSPEDLKKKVAESDALIVRSGTKVTREVFEAAK 143
Query: 275 -KLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTA 451
+LKVVGRAG G+DN+D+ +A + G V+NAP AN ++A E L+ +AR+V A +
Sbjct: 144 GRLKVVGRAGVGIDNVDLQAATEHGCLVVNAPTANTVAAAEHGIALLASMARNVAQADAS 203
Query: 452 LKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFH 631
+KAG+W+R+ Y G L GKTLA++G G+VG EVA R GM +I DP+ AD+
Sbjct: 204 IKAGKWERSKYVGVSLVGKTLAVMGFGKVGTEVARRAKGLGMTVISHDPYAPADRARALG 263
Query: 632 CTKMELEDIWPLADYITLHTPLIXSTRNFIN 724
+ + AD+++LH PL +T+ N
Sbjct: 264 VDLVSFDQAISTADFVSLHMPLTPATKKVFN 294
>UniRef50_O67741 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Aquifex aeolicus|Rep: D-3-phosphoglycerate dehydrogenase
- Aquifex aeolicus
Length = 533
Score = 167 bits (406), Expect = 2e-40
Identities = 87/212 (41%), Positives = 128/212 (60%), Gaps = 2/212 (0%)
Frame = +2
Query: 95 VLIVDGVGAKCAELLNAYG-IATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAG 271
VLI D + + ELL + + IS EELL I + DA++ RS T VTKE+L+
Sbjct: 4 VLITDPIAPEGIELLQKDPEVEVYNEPDISYEELLEIIKDFDAIITRSRTPVTKELLERA 63
Query: 272 VKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTA 451
KLKVVGRAG GVDN+D++ A K+G+ V+N PGAN + A ELT ML + R+ A +
Sbjct: 64 EKLKVVGRAGVGVDNVDIEEATKRGILVVNTPGANTIGATELTMMHMLTIMRNGHKAHES 123
Query: 452 LKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFH 631
+ +WDR + G EL G+ L I+GLG +G +VA R AFGM ++ +DP++ ++ +
Sbjct: 124 MLNYKWDRKKFMGEELYGRILGIIGLGNIGSQVAIRAKAFGMKVMAYDPYIPREKAEKLG 183
Query: 632 CTKME-LEDIWPLADYITLHTPLIXSTRNFIN 724
++ L D+ D +T+H PL T+N I+
Sbjct: 184 VKLVDNLHDMLREIDVLTIHAPLTHETKNMID 215
>UniRef50_A7CYD6 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Opitutaceae bacterium TAV2|Rep: D-3-phosphoglycerate
dehydrogenase - Opitutaceae bacterium TAV2
Length = 529
Score = 166 bits (403), Expect = 6e-40
Identities = 83/211 (39%), Positives = 129/211 (61%), Gaps = 1/211 (0%)
Frame = +2
Query: 95 VLIVDGVGAK-CAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAG 271
+L+ D + K A L G S E++L + + A+ VRS T++T+EV+ A
Sbjct: 3 ILVADKISPKGVAYLRQQEGFEVVEAYGSSPEKVLELVKDVHAIAVRSETKITREVIAAA 62
Query: 272 VKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTA 451
+LKVVGRAG GVDN+DV++A ++GV V+N P N ++ ELT T +L +R V A+ +
Sbjct: 63 PQLKVVGRAGVGVDNVDVEAATERGVVVMNTPAGNTIATAELTFTHILCGSRPVSQAAAS 122
Query: 452 LKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFH 631
++ G+WDR ++G EL KTL ++G+GR+G EVA R AFGM ++ +DP+++ +
Sbjct: 123 MREGKWDRKSFSGVELFKKTLGVIGMGRIGGEVARRAVAFGMKVLAYDPYLAPSRAKAMQ 182
Query: 632 CTKMELEDIWPLADYITLHTPLIXSTRNFIN 724
L++I ADYIT+H PL T+ I+
Sbjct: 183 VEVATLDEILAQADYITVHMPLTDDTKYMID 213
>UniRef50_Q2LGV1 Cluster: Phosphoglycerate dehydrogenase; n=6;
Halobacteriaceae|Rep: Phosphoglycerate dehydrogenase -
Haloquadratum walsbyi
Length = 536
Score = 165 bits (401), Expect = 1e-39
Identities = 85/210 (40%), Positives = 124/210 (59%)
Frame = +2
Query: 95 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 274
VL+ D + E L A G + T I E LL I + +ALVVRS T V + V +A
Sbjct: 7 VLVTDPIDDAGLERLRAAGHSVETAYDIGDEALLNTITDVNALVVRSGTDVNEAVFEAAS 66
Query: 275 KLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL 454
L +VGRAG GVDNID+D+A + GV V NAP N +A E T + AR + A L
Sbjct: 67 DLIIVGRAGIGVDNIDIDAATEHGVIVANAPEGNVRAAAEHTVAMTFAGARSIPQAHARL 126
Query: 455 KAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHC 634
+ G W ++ Y G+E+ GKTL ++GLGRVG+EVA R+ + GM+++ +DP++S D+ +
Sbjct: 127 RTGEWAKSEYLGTEVNGKTLGVVGLGRVGQEVAKRLESLGMDLVAYDPYISEDRAERLGA 186
Query: 635 TKMELEDIWPLADYITLHTPLIXSTRNFIN 724
+E + A+++T+HTPL T I+
Sbjct: 187 ELVEFDTCLERAEFLTVHTPLTSETAGMIS 216
>UniRef50_O33116 Cluster: D-3-phosphoglycerate dehydrogenase; n=28;
Actinomycetales|Rep: D-3-phosphoglycerate dehydrogenase
- Mycobacterium leprae
Length = 528
Score = 165 bits (400), Expect = 1e-39
Identities = 79/183 (43%), Positives = 119/183 (65%)
Frame = +2
Query: 182 KEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVIN 361
+ +LL +P DAL+VRSAT V EVL A KLK+V RAG G+DN+DVD+A +GV V+N
Sbjct: 34 RTKLLAAVPEADALLVRSATTVDAEVLAAAPKLKIVARAGVGLDNVDVDAATARGVLVVN 93
Query: 362 APGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVG 541
AP +N SA E L+L +R + A +L+A W R+ ++G+E+ GKT+ ++GLGR+G
Sbjct: 94 APTSNIHSAAEHALALLLAASRQIAEADASLRAHIWKRSSFSGTEIFGKTVGVVGLGRIG 153
Query: 542 REVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYITLHTPLIXSTRNFI 721
+ VA R+ AFG ++I +DP+V+ + AQ M +D+ AD+I++H P T I
Sbjct: 154 QLVAARIAAFGAHVIAYDPYVAPARAAQLGIELMSFDDLLARADFISVHLPKTPETAGLI 213
Query: 722 NAD 730
+ +
Sbjct: 214 DKE 216
>UniRef50_Q1AXS3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Rubrobacter xylanophilus DSM 9941|Rep:
D-3-phosphoglycerate dehydrogenase - Rubrobacter
xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 527
Score = 164 bits (398), Expect = 2e-39
Identities = 84/213 (39%), Positives = 128/213 (60%), Gaps = 1/213 (0%)
Frame = +2
Query: 95 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 274
VL+ + + + ELL +S ELL I +D L+VRSAT+VT EV++A
Sbjct: 3 VLVTEKLAERGVELLRRE-FEVDVLLGLSPGELLERIGEYDGLIVRSATKVTAEVIEAAG 61
Query: 275 KLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL 454
+LK +GRAG GVDNID+++A K+G+ V NAP +N ++A E T LML +AR + A +L
Sbjct: 62 RLKAIGRAGIGVDNIDIEAATKRGILVANAPESNTVAAAEHTLGLMLAVARRIPAADASL 121
Query: 455 KAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHC 634
+ G W+RA + G E+A KTL ++GLG VG VA GM ++ +DP+VS ++ +
Sbjct: 122 RRGEWNRAAFKGVEVAEKTLGLVGLGHVGSIVARGALGMGMRVLAYDPYVSEERMRSMNV 181
Query: 635 TKM-ELEDIWPLADYITLHTPLIXSTRNFINAD 730
+ LE+I+ AD+++LH P T + +
Sbjct: 182 ERAGSLEEIFEEADFVSLHVPRTPQTTGMVGEE 214
>UniRef50_A7P9P5 Cluster: Chromosome chr3 scaffold_8, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr3 scaffold_8, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 653
Score = 163 bits (396), Expect = 4e-39
Identities = 84/212 (39%), Positives = 128/212 (60%), Gaps = 1/212 (0%)
Frame = +2
Query: 92 SVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAG 271
+VL+ + +GA +LL + +S EEL +I DAL+VRS T+V++EV +A
Sbjct: 113 TVLVAEKLGAAGLDLLKDFANVDCAY-NLSPEELCTKISLCDALIVRSGTKVSREVFEAS 171
Query: 272 V-KLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPAST 448
+LKVVGRAG G+DN+D+ +A + G V+NAP AN ++A E L+ +AR+V A
Sbjct: 172 SGRLKVVGRAGVGIDNVDLAAATEHGCLVVNAPTANTVAAAEHGIALLTAMARNVAQADA 231
Query: 449 ALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQF 628
++K+G+W R Y G L GKTLA++G G+VG EV R GM++I DP+ +AD+
Sbjct: 232 SVKSGKWQRNKYVGVSLVGKTLAVMGFGKVGSEVTRRAKGLGMHVIAHDPYAAADRARAI 291
Query: 629 HCTKMELEDIWPLADYITLHTPLIXSTRNFIN 724
+ ++ AD+I+LH PL +T +N
Sbjct: 292 GVELVGFDEAISTADFISLHMPLTPATSKMLN 323
>UniRef50_Q8ZTC7 Cluster: D-3-phosphoglycerate dehydrogenase; n=5;
Thermoproteaceae|Rep: D-3-phosphoglycerate dehydrogenase
- Pyrobaculum aerophilum
Length = 307
Score = 163 bits (396), Expect = 4e-39
Identities = 81/213 (38%), Positives = 126/213 (59%)
Frame = +2
Query: 92 SVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAG 271
S LIVD V E L GI ISK++L+ I N++ L+ R ++ K+++DAG
Sbjct: 2 SALIVDKVDETLKERLERIGIKVDLAPGISKDDLIKIIKNYNILIFRGRLKIDKDIMDAG 61
Query: 272 VKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTA 451
LK++ R G G+DN+DV+ A KKG+ V++AP A + S ELT L+ +AR + +
Sbjct: 62 QNLKILARYGVGLDNVDVEYAVKKGIAVVSAPNAPSQSVAELTIGLLFSVARRIPLLNAK 121
Query: 452 LKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFH 631
+KAG W + Y G E+AGKT+ I+G GR+GR VA + GMNI+ D + + A+
Sbjct: 122 VKAGEWPKGKYIGIEIAGKTMGIVGFGRIGRFVAQMAKSLGMNILASDVIDVSKEVAKIG 181
Query: 632 CTKMELEDIWPLADYITLHTPLIXSTRNFINAD 730
++ LE++ +D +T+H PL T + +NA+
Sbjct: 182 GRQVPLEELLRQSDVVTIHVPLTPETYHLLNAE 214
>UniRef50_UPI00015BAF48 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Ignicoccus hospitalis
KIN4/I|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Ignicoccus hospitalis
KIN4/I
Length = 308
Score = 160 bits (389), Expect = 3e-38
Identities = 88/213 (41%), Positives = 127/213 (59%), Gaps = 2/213 (0%)
Frame = +2
Query: 98 LIVDGVGAKCAELLNAYGIATTTKAKISKEELLME-IPNHDALVVRSATQVTKEVLDAGV 274
L+ D V ELL GI + K E+L E I D L+VRS T+V +EV++A
Sbjct: 5 LVTDKVHPAGLELLREKGIEVVEDLEAYKPEVLKERIKGFDVLIVRSRTKVRREVIEAAD 64
Query: 275 KLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL 454
KLKV+ RAG+G+DNID+++A +KG+ V+NAP A + EL +M+VLAR + L
Sbjct: 65 KLKVIARAGSGLDNIDLEAAKEKGIKVVNAPDALKNAVAELVIGMMVVLARRAHYSYRKL 124
Query: 455 KAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHC 634
G W++ + G ELAGKTL ++G GR+GREVA + A GMN+I +D ++ +
Sbjct: 125 LEGEWEKVM--GFELAGKTLGVVGFGRIGREVAKKAKALGMNVIAYDVVDLSETAKEMGV 182
Query: 635 T-KMELEDIWPLADYITLHTPLIXSTRNFINAD 730
+LE++ +D ++LH PL TRN IN D
Sbjct: 183 EFTQDLEELLRKSDVVSLHVPLTEQTRNMINRD 215
>UniRef50_A6C2G1 Cluster: Phosphoglycerate dehydrogenase; n=1;
Planctomyces maris DSM 8797|Rep: Phosphoglycerate
dehydrogenase - Planctomyces maris DSM 8797
Length = 316
Score = 159 bits (385), Expect = 9e-38
Identities = 82/215 (38%), Positives = 127/215 (59%), Gaps = 3/215 (1%)
Frame = +2
Query: 86 IKSVLIVDGV-GAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVL 262
+ VL+ + + G L+ + + + + L +I N AL+VR+ T+V +E++
Sbjct: 1 MSDVLVTENIQGVSMNRLIQEHDVEFDAYLWQNIDLLKQKIQNTRALIVRNQTKVDRELI 60
Query: 263 DAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPA 442
DA +LK++ RAGAG+DN+D + A +KG+ V P AN+LS ELT LML L R + A
Sbjct: 61 DAAPELKIIARAGAGLDNVDTEYAHEKGIVVCFTPDANSLSVAELTIGLMLALMRKIPEA 120
Query: 443 STALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSAD--Q 616
G W+R +TG+EL GK+ ++GLGR+G ATR AFGMNI+ DPF+ AD Q
Sbjct: 121 RQDTLTGGWNRLKFTGTELYGKSFGLIGLGRIGSFTATRAKAFGMNILAADPFLKADAPQ 180
Query: 617 CAQFHCTKMELEDIWPLADYITLHTPLIXSTRNFI 721
+ + T + L+D+ +D ++ H+PL TR +
Sbjct: 181 LKKLNATLLSLDDLLAESDVVSCHSPLTPDTRKML 215
>UniRef50_A1IDH6 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
Deltaproteobacteria|Rep: D-3-phosphoglycerate
dehydrogenase - Candidatus Desulfococcus oleovorans Hxd3
Length = 532
Score = 158 bits (383), Expect = 2e-37
Identities = 80/212 (37%), Positives = 124/212 (58%), Gaps = 2/212 (0%)
Frame = +2
Query: 95 VLIVDGVGAK-CAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAG 271
VL+ D + A + L N G A K + EEL I +DAL++RSAT+VT ++L+AG
Sbjct: 5 VLVSDTIDASGVSRLENESGFAVDVKTGLPPEELKSIIGQYDALIIRSATKVTADILEAG 64
Query: 272 V-KLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPAST 448
KLK V RAG G+DN+D+ +A K GV V+N P N ++ E T +M+ L R++ +
Sbjct: 65 APKLKAVARAGIGLDNVDIPAATKHGVAVMNTPEGNVVTTAEHTIAMMMALTRNIPQGTL 124
Query: 449 ALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQF 628
+L++G+W++ G E+ KTL ++G G++G VA R MN+I FDP ++
Sbjct: 125 SLRSGQWEKKKLQGREVFNKTLGVIGFGKIGSIVADRARQLKMNVIVFDPNIARTTIENE 184
Query: 629 HCTKMELEDIWPLADYITLHTPLIXSTRNFIN 724
+ L+D++ ADYIT+H P + T +N
Sbjct: 185 GFEYVSLDDLFARADYITVHVPKLKQTVGLLN 216
>UniRef50_Q8TYK0 Cluster: Predicted dehydrogenase related to
phosphoglycerate dehydrogenase; n=9; Archaea|Rep:
Predicted dehydrogenase related to phosphoglycerate
dehydrogenase - Methanopyrus kandleri
Length = 522
Score = 157 bits (381), Expect = 3e-37
Identities = 79/213 (37%), Positives = 125/213 (58%), Gaps = 1/213 (0%)
Frame = +2
Query: 95 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 274
+L+ D + L G + +EE+ + + DA VVRS T+VT+E+++
Sbjct: 4 ILVTDPIHEDALRKLEELGEVVVLE-DADEEEIREHVRDADAWVVRSGTRVTRELIEEAK 62
Query: 275 KLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL 454
LKV+ RAG GVDNIDV +A ++G+ V+NAP ++++S E T L+L LAR + A ++
Sbjct: 63 NLKVIARAGVGVDNIDVKAATERGIIVVNAPESSSISVAEHTMGLILALARKIPQADRSV 122
Query: 455 KAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHC 634
+ G WDR + G ELAGKTL ++GLGR+G++VA R AF M + +DP++ +
Sbjct: 123 RRGEWDRKRFMGVELAGKTLGLIGLGRIGQQVAKRAKAFEMEVTAYDPYIPEKVAEELGV 182
Query: 635 TKM-ELEDIWPLADYITLHTPLIXSTRNFINAD 730
+ ELE++ AD +++H PL T I +
Sbjct: 183 ELVDELEELLERADVVSIHVPLTEETEGMIGEE 215
>UniRef50_Q0J5C2 Cluster: Os08g0447000 protein; n=11;
Viridiplantae|Rep: Os08g0447000 protein - Oryza sativa
subsp. japonica (Rice)
Length = 666
Score = 154 bits (373), Expect = 2e-36
Identities = 83/196 (42%), Positives = 117/196 (59%), Gaps = 13/196 (6%)
Frame = +2
Query: 176 ISKEELLMEIPNHDALVVRSATQVTKEVLDAGV-KLKVVGRAGAGVDNIDVDSAGKKGVG 352
+S ELL ++ DAL+VRS T+VT+EVL+AG +L+VVGRAG G+DN+D+ +A + G
Sbjct: 106 MSPAELLAKVAQFDALIVRSGTKVTREVLEAGRGRLRVVGRAGVGIDNVDLQAATEAGCL 165
Query: 353 VINAPGANALSACELTCTLMLVLARHVVPASTALKA------------GRWDRALYTGSE 496
V+NAP AN ++A E L+ +AR+V A ALKA G+W R Y G
Sbjct: 166 VVNAPTANTVAAAEHGIALLASMARNVSQADAALKAVYSRTLTVFTAQGKWQRTKYVGVS 225
Query: 497 LAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADY 676
L GKTLA++G G+VG EVA R GM++I DP+ AD+ + ++ AD+
Sbjct: 226 LVGKTLAVMGFGKVGSEVARRAKGLGMHVIAHDPYAPADRARAIGAELVSFDEAIGRADF 285
Query: 677 ITLHTPLIXSTRNFIN 724
I+LH PL +T N
Sbjct: 286 ISLHMPLTPATSKVFN 301
>UniRef50_Q9RUU0 Cluster: D-3-phosphoglycerate dehydrogenase; n=4;
Deinococci|Rep: D-3-phosphoglycerate dehydrogenase -
Deinococcus radiodurans
Length = 544
Score = 153 bits (370), Expect = 6e-36
Identities = 78/197 (39%), Positives = 120/197 (60%), Gaps = 2/197 (1%)
Frame = +2
Query: 137 LNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDA-GVKLKVVGRAGAGVD 313
L+ G + + +EE L +P++DAL+ RS T+V +E+LDA G +LKV+GR G GVD
Sbjct: 33 LDHEGFQIDYQGNLEREETLRRLPDYDALITRSRTKVDRELLDAAGPRLKVIGRGGVGVD 92
Query: 314 NIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGS 493
NID++ A ++G+ V+NAP +N +SA EL ++ AR + + +AG WDR + G
Sbjct: 93 NIDLEYASRRGLLVLNAPESNNVSAAELAVMHLMAAARGLTRSDRKTRAGEWDRK-FLGL 151
Query: 494 ELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTK-MELEDIWPLA 670
EL KTL I+GLGR+G VA R MN++ +DP+V ++ + + L+++
Sbjct: 152 ELTDKTLGIVGLGRIGSIVADRAQGLHMNVVAYDPYVPENKFERLGVQRAASLDELLGQV 211
Query: 671 DYITLHTPLIXSTRNFI 721
D +T+HTPL TR I
Sbjct: 212 DALTVHTPLTDETRGMI 228
>UniRef50_A4MA79 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Petrotoga mobilis
SJ95|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Petrotoga mobilis SJ95
Length = 310
Score = 147 bits (356), Expect = 3e-34
Identities = 75/188 (39%), Positives = 116/188 (61%), Gaps = 1/188 (0%)
Frame = +2
Query: 164 TKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKK 343
T + K+ L +I D L+VRSAT+VTKE+L+ KLK+V RAG G+DNIDVD+A K
Sbjct: 27 TSEHLEKDVLKDKIKEIDVLIVRSATKVTKEILEHADKLKIVARAGMGLDNIDVDTAKLK 86
Query: 344 GVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAIL 523
G+ V+N PG N+LS EL ++L + RH+ + LK +W++ G EL+ KT I+
Sbjct: 87 GITVLNTPGQNSLSVAELVIGMVLDIYRHITRGTIGLKNEQWEKKQLEGFELSQKTFGII 146
Query: 524 GLGRVGREVATRMYAFGMNIIGFDPF-VSADQCAQFHCTKMELEDIWPLADYITLHTPLI 700
G G VG+ +A + F N + +D F +SA++ ++ ++ LE++ +D I+LH P
Sbjct: 147 GFGYVGKNLAQLLKGFQTNTLVYDVFEISAEEQKNYNVRQVSLEELLQNSDIISLHIPKN 206
Query: 701 XSTRNFIN 724
T +FI+
Sbjct: 207 EKTYHFIS 214
>UniRef50_A4FIF2 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Saccharopolyspora erythraea NRRL 2338|Rep:
D-3-phosphoglycerate dehydrogenase - Saccharopolyspora
erythraea (strain NRRL 23338)
Length = 316
Score = 147 bits (355), Expect = 4e-34
Identities = 77/192 (40%), Positives = 120/192 (62%), Gaps = 4/192 (2%)
Frame = +2
Query: 131 ELLNAYGIATT----TKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRA 298
E+L A G A T+A + ++LL +P DAL+V VT EV++AG +L+V+ +
Sbjct: 20 EILEAAGSAAVRPHETRA-MPADDLLARVPEADALIV-GMDLVTAEVIEAGPRLRVIAKH 77
Query: 299 GAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRA 478
G GVDNID+D+A +G+ V+ APG+N+ + ELT LM+ AR + A TA+ AG W +
Sbjct: 78 GVGVDNIDLDAARARGIPVVFAPGSNSRAVAELTFGLMIAAARRIAAAHTAVVAGDWPK- 136
Query: 479 LYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDI 658
LY G ELAG+TL ++G GR+GR +A AFGM ++G+DPF+ + + + +
Sbjct: 137 LY-GPELAGRTLGVIGFGRIGRLLAGYAQAFGMTVVGYDPFLDDGELTERGVRPVSFSEC 195
Query: 659 WPLADYITLHTP 694
++D+++LH P
Sbjct: 196 LAMSDFVSLHLP 207
>UniRef50_A0RW58 Cluster: Phosphoglycerate dehydrogenase; n=3;
Crenarchaeota|Rep: Phosphoglycerate dehydrogenase -
Cenarchaeum symbiosum
Length = 310
Score = 146 bits (354), Expect = 5e-34
Identities = 76/215 (35%), Positives = 118/215 (54%), Gaps = 1/215 (0%)
Frame = +2
Query: 89 KSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDA 268
++VLI D +L G+ + K +I+ EEL E P + ++VRS T +T E++ +
Sbjct: 5 ETVLICDKADPVLGRILQQNGLRVSYKPEITPEELAAEAPGYSIIIVRSRTTITGEIIRS 64
Query: 269 GVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPAST 448
K++ R G G+DNID+ +A GV VINA + EL +ML +AR + A
Sbjct: 65 AKDCKIIARVGVGLDNIDLAAAESAGVRVINAVEGATTAVSELVLGMMLCMARQIPRADR 124
Query: 449 ALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPF-VSADQCAQ 625
++ G+W + G+EL GK L I+GLG +GR + MNIIG D + A+ +
Sbjct: 125 GIRGGKWLKGELGGTELKGKYLGIVGLGNIGRRLGRLARGMNMNIIGHDVVPIDAEFSRE 184
Query: 626 FHCTKMELEDIWPLADYITLHTPLIXSTRNFINAD 730
K +L + +DY++LH PL+ STR+ INA+
Sbjct: 185 VGLMKTDLNTLLGSSDYVSLHVPLLDSTRHMINAE 219
>UniRef50_A6DQ00 Cluster: SerA; n=1; Lentisphaera araneosa
HTCC2155|Rep: SerA - Lentisphaera araneosa HTCC2155
Length = 522
Score = 145 bits (352), Expect = 9e-34
Identities = 75/215 (34%), Positives = 120/215 (55%)
Frame = +2
Query: 89 KSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDA 268
+ VLI + ++L G +A + EL P+ + ++VRS ++T EV+D
Sbjct: 3 QKVLIPTKLSTAAKDILEGNGFTVVQEAGVDLVELAKAHPDTEGMIVRSE-KLTPEVIDL 61
Query: 269 GVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPAST 448
LK V RAGAG + ID+ A K + V+N PGAN+ + E +M+ AR +
Sbjct: 62 FPNLKAVVRAGAGYNTIDIQYARSKDITVMNTPGANSNAVAEEAVGMMISCARFFIEGDR 121
Query: 449 ALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQF 628
+ +AG W +A G EL GKT+ I G G +G+ +A R+ F ++I+ +DPFVS D+ A+F
Sbjct: 122 STRAGEWKKAQLQGFELTGKTVGIAGFGNIGQLLAKRLSGFEVDILVYDPFVSEDKLAEF 181
Query: 629 HCTKMELEDIWPLADYITLHTPLIXSTRNFINADV 733
+ LE+++ +D+I+LH P T N I+ D+
Sbjct: 182 GAKNVSLEELFAGSDFISLHMPATKETANVISTDL 216
>UniRef50_Q1K3M3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Desulfuromonas acetoxidans DSM 684|Rep:
D-3-phosphoglycerate dehydrogenase - Desulfuromonas
acetoxidans DSM 684
Length = 528
Score = 143 bits (347), Expect = 3e-33
Identities = 74/213 (34%), Positives = 122/213 (57%), Gaps = 1/213 (0%)
Frame = +2
Query: 95 VLIVDGVGAKCAELLN-AYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAG 271
VLI D + +L + A GI + I+ + LL I N+DAL+VR T V++E++ A
Sbjct: 3 VLISDNFSSAGLKLFDEAEGITADYQPGITHDNLLKIINNYDALIVRGGTTVSEELIFAA 62
Query: 272 VKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTA 451
+LK++ RAG GV+NI +D+A KG+ V N P + + E +M+ LAR + A +
Sbjct: 63 KRLKIIARAGIGVENIAMDAANIKGIVVTNTPLGSTTTIAEHAIAMMMSLARLIPQAHES 122
Query: 452 LKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFH 631
+ G+W + GS++ KTL ++G G++GR V M++ +DP++S + +
Sbjct: 123 MSQGKWQSTEFLGSDINDKTLGVIGGGKIGRRVIEYARGLHMHVNLYDPYLSEEVITRLG 182
Query: 632 CTKMELEDIWPLADYITLHTPLIXSTRNFINAD 730
+K+ LED+ AD+I+LH PL T +NA+
Sbjct: 183 ASKVSLEDLLSTADFISLHLPLTLETEQILNAE 215
>UniRef50_Q0EUV6 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=4; Thermoanaerobacter
ethanolicus|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Thermoanaerobacter
ethanolicus X514
Length = 320
Score = 143 bits (347), Expect = 3e-33
Identities = 72/182 (39%), Positives = 114/182 (62%)
Frame = +2
Query: 176 ISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGV 355
+S EEL+ + + DAL+V + +VT++V++AG KLKV+ R G G DN+D+++A KKG+ V
Sbjct: 40 LSAEELIPLVKDADALIVGN-DKVTEDVINAGKKLKVISRYGVGYDNVDLNAAKKKGIVV 98
Query: 356 INAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGR 535
N P AN S +L LMLVLAR+++ +K+G W R + G+E+ GKTL I+GLG+
Sbjct: 99 TNTPNANNNSVADLVIGLMLVLARNLLAVDRIVKSGGWKRIM--GTEIYGKTLGIIGLGK 156
Query: 536 VGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYITLHTPLIXSTRN 715
+G+ VA R F MN++ +D + ++ T E++ +D +T+H PL T+
Sbjct: 157 IGKGVAKRAKGFDMNVLCYDVYPDLKFSEEYGVTYCSFEELLKQSDIVTIHVPLTPETKG 216
Query: 716 FI 721
I
Sbjct: 217 LI 218
>UniRef50_Q97N23 Cluster: D-3-phosphoglycerate dehydrogenase; n=10;
Clostridiaceae|Rep: D-3-phosphoglycerate dehydrogenase -
Clostridium acetobutylicum
Length = 305
Score = 138 bits (335), Expect = 1e-31
Identities = 77/177 (43%), Positives = 110/177 (62%), Gaps = 6/177 (3%)
Frame = +2
Query: 182 KEELLMEIPNHDALVVRSATQVTKEVLDA----GVKLKVVGRAGAGVDNIDVDSAGKKGV 349
K+ELL++I D LVVRSAT+VTKEV+DA G KLK++ RAG GVDNIDV A KG+
Sbjct: 32 KDELLVKIKEFDVLVVRSATKVTKEVIDAATVKGAKLKLIIRAGVGVDNIDVTYARDKGL 91
Query: 350 GVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGL 529
V N P A++ S EL M ++R + A+ ++ G+W++ YTG+E+ GKTL ++G
Sbjct: 92 TVNNTPNASSASVAELAIGHMFAVSRFINTANVTMRQGKWEKKAYTGTEIFGKTLGLIGF 151
Query: 530 GRVGREVATRMYAFGMNIIGFD--PFVSADQCAQFHCTKMELEDIWPLADYITLHTP 694
GR+ REVA R A GM +I D V +F+ ++ + AD+++LH P
Sbjct: 152 GRIAREVAKRAEALGMKVIYNDICGKVVGYDSYEFY---DDINGLLREADFVSLHIP 205
>UniRef50_Q8EMJ8 Cluster: Hypothetical conserved protein; n=1;
Oceanobacillus iheyensis|Rep: Hypothetical conserved
protein - Oceanobacillus iheyensis
Length = 319
Score = 138 bits (334), Expect = 1e-31
Identities = 75/214 (35%), Positives = 119/214 (55%), Gaps = 2/214 (0%)
Frame = +2
Query: 95 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 274
VL+ + + LL G + + L+ + + DA++ R+ +++VL+
Sbjct: 5 VLVPQKIAQEGIRLLEENGASIVVPPSHDEATLVEYVSDVDAIIARTEIY-SEKVLENAN 63
Query: 275 KLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL 454
+LK++ R G GVDNIDV +A K G+ V N P AN + EL T ML RH++P A+
Sbjct: 64 RLKIIARHGIGVDNIDVKAATKYGIKVTNTPSANINAVAELVLTFMLASTRHLLPIDEAV 123
Query: 455 KAGRWD-RALYTGSELAGKTLAILGLGRVGREVATR-MYAFGMNIIGFDPFVSADQCAQF 628
+AG +D R G EL GKT+ I+G G +GR +A + GMNI+ FDP+V+A+ +
Sbjct: 124 RAGNFDIRNQLFGYELNGKTVGIIGFGNIGRLIAEKCRLGLGMNIVVFDPYVTAESVEPY 183
Query: 629 HCTKMELEDIWPLADYITLHTPLIXSTRNFINAD 730
LED+ ++D +TLH P + +T + I+ D
Sbjct: 184 VELTESLEDLLRISDVVTLHVPYVRATHHLIHKD 217
>UniRef50_Q97ZK1 Cluster: D-3-phosphoglycerate dehydrogenase; n=4;
Sulfolobaceae|Rep: D-3-phosphoglycerate dehydrogenase -
Sulfolobus solfataricus
Length = 326
Score = 136 bits (330), Expect = 4e-31
Identities = 80/219 (36%), Positives = 122/219 (55%), Gaps = 2/219 (0%)
Frame = +2
Query: 80 VDIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEV 259
+D K VLI D V L G+ K +I++EELL I + L+VRS T+V KE+
Sbjct: 16 LDFK-VLITDPVDQYMIRTLQNNGLIVDYKPEITREELLKIIDQYQVLIVRSRTKVDKEI 74
Query: 260 LDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVP 439
+ GV LK++ RAG G+DNID + A K+ + ++ APGA+ SA ELT L++ AR +
Sbjct: 75 IRYGVNLKIIARAGIGLDNIDTEEASKRNIKIVYAPGASTDSAAELTIGLLIAAARKLYD 134
Query: 440 ASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQC 619
+ K G + + G ELAGKT+ I+G GR+G +VA A MN+I +D ++ +
Sbjct: 135 SMNMAKGGIFKK--IEGIELAGKTIGIVGFGRIGTKVAKVCKALDMNVIAYD-VINIKEK 191
Query: 620 AQFHCTKM--ELEDIWPLADYITLHTPLIXSTRNFINAD 730
A ++ LE++ +D IT H + + +N D
Sbjct: 192 ANIVGVRVAESLEELLKNSDVITFHVTVGKDAKPILNKD 230
>UniRef50_A6PUG1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Victivallis vadensis
ATCC BAA-548|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Victivallis vadensis ATCC
BAA-548
Length = 524
Score = 132 bits (320), Expect = 6e-30
Identities = 67/213 (31%), Positives = 118/213 (55%)
Frame = +2
Query: 86 IKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLD 265
++ VLI + A +L+ G +L+ + + L+VRS ++T E++D
Sbjct: 1 MRKVLIPTKLDKFAATMLSDRGYNVVLDGATPLADLVKANSDAEVLIVRSE-KITPEIID 59
Query: 266 AGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPAS 445
+LK++ RAGAG + ID+ A K + V+N PGAN+ + E +ML +RH++PA
Sbjct: 60 LLPQLKLIVRAGAGFNTIDIKYARKHDIDVMNTPGANSNAVAEEVVAMMLAASRHLIPAD 119
Query: 446 TALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQ 625
+ + G W+++ + G EL GKT+ ILGLG +G+ + R+ F M ++G+DP +S +
Sbjct: 120 ISTRKGDWEKSKFMGRELTGKTVGILGLGHIGQLLVKRLAGFEMKVLGYDPMLSPALADK 179
Query: 626 FHCTKMELEDIWPLADYITLHTPLIXSTRNFIN 724
++ I+ +D+++LH P TR +N
Sbjct: 180 LGVELTTVDRIFAESDFVSLHIPENDETRGMVN 212
>UniRef50_Q5KN70 Cluster: D-3-phosphoglycerate dehydrogenase 2,
putative; n=2; Filobasidiella neoformans|Rep:
D-3-phosphoglycerate dehydrogenase 2, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 508
Score = 132 bits (318), Expect = 1e-29
Identities = 70/216 (32%), Positives = 125/216 (57%), Gaps = 4/216 (1%)
Frame = +2
Query: 95 VLIVDGVGAKCAELLNAYG--IATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDA 268
+L+++ + A+ L + G + TKA ++EEL+ ++PN+ A+ +RS T++T +V+DA
Sbjct: 101 ILLLENINLDAADYLKSQGYEVDHVTKA-YTEEELIAKLPNYHAIGIRSKTKITAKVIDA 159
Query: 269 GVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPAST 448
+L +G G + +D++ A K+G+ V N+P +N+ S EL + ++ L+R ++ +
Sbjct: 160 NPQLLAIGCFCIGTNQVDLEHAAKRGIAVFNSPFSNSRSVAELVISEIIALSRQIIDRTH 219
Query: 449 ALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFD--PFVSADQCA 622
++AG W++ E+ GKTL I+G G +G +++ AFGM++I FD P +
Sbjct: 220 EMRAGIWNKLSKNCWEIRGKTLGIVGYGHIGSQLSVLAEAFGMSVIYFDVVPIMPLGSAR 279
Query: 623 QFHCTKMELEDIWPLADYITLHTPLIXSTRNFINAD 730
Q LED+ AD+ITLH P I T + A+
Sbjct: 280 QVD----TLEDLLSRADFITLHVPEIPDTIGMMGAE 311
>UniRef50_A1RDF9 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=1; Arthrobacter
aurescens TC1|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase family protein - Arthrobacter aurescens
(strain TC1)
Length = 329
Score = 131 bits (317), Expect = 1e-29
Identities = 64/174 (36%), Positives = 104/174 (59%), Gaps = 2/174 (1%)
Frame = +2
Query: 209 NHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSA 388
N D +++R+ T T+E+++A +LK++ R G G DN+D+ +A + V V + PG+N+ +
Sbjct: 41 NIDGVILRAET-FTREMIEASPRLKIIARHGVGTDNVDIPAASEHSVWVTSTPGSNSNAV 99
Query: 389 CELTCTLMLVLARHVVPASTALKAGRW--DRALYTGSELAGKTLAILGLGRVGREVATRM 562
E +L+L L R ++PA+ + AG W R G EL+G+TL I+G G +G+ VAT
Sbjct: 100 AEHVFSLLLSLTRRIIPAANRVLAGTWAEGRGDLVGFELSGRTLGIVGFGAIGKRVATIA 159
Query: 563 YAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYITLHTPLIXSTRNFIN 724
FGM ++ DP +A +EL+ ++ AD ITLH PL+ TR+ I+
Sbjct: 160 NGFGMRVLASDPIATAADAEAAGAVLVELDTLYDGADIITLHAPLLSGTRHMIS 213
>UniRef50_A6EBH4 Cluster: Phosphoglycerate dehydrogenase; n=1;
Pedobacter sp. BAL39|Rep: Phosphoglycerate dehydrogenase
- Pedobacter sp. BAL39
Length = 309
Score = 131 bits (316), Expect = 2e-29
Identities = 72/214 (33%), Positives = 121/214 (56%), Gaps = 2/214 (0%)
Frame = +2
Query: 95 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 274
+LIVD + A E A G + ++ + L I ++D + VR+ ++ +E++DAG
Sbjct: 6 ILIVDELHAIFKERAAAMGYEVHDEPNFTRAQTLAAIADYDGIAVRTKFRIDRELIDAGT 65
Query: 275 KLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL 454
KLK + RAGAG+DNID A ++ + +INAP N + E LML L + A +
Sbjct: 66 KLKFIARAGAGLDNIDEAVALERNIHLINAPEGNMDAVGEHAVGLMLSLMNNFRNADMEI 125
Query: 455 KAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVS--ADQCAQF 628
+ G+WDR G EL GKT+ I+G G +G +A ++ FG+ +I +D + + +DQ A+
Sbjct: 126 RKGKWDREGNRGYELKGKTVGIIGYGFMGSSLARKLSGFGVQVIAYDKYKTGFSDQYAR- 184
Query: 629 HCTKMELEDIWPLADYITLHTPLIXSTRNFINAD 730
++ +E+I L+D ++ H PL TR ++ +
Sbjct: 185 ---EVSMEEIVKLSDVLSFHIPLTNETRQLVDEE 215
>UniRef50_A6CKS4 Cluster: Putative uncharacterized protein; n=1;
Bacillus sp. SG-1|Rep: Putative uncharacterized protein
- Bacillus sp. SG-1
Length = 322
Score = 130 bits (314), Expect = 3e-29
Identities = 69/214 (32%), Positives = 123/214 (57%), Gaps = 2/214 (0%)
Frame = +2
Query: 95 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 274
VLI + + +LL G ++E L+ + + DA+++R+A ++++ V++
Sbjct: 5 VLIPQPIAKEGIDLLEKEGAEVIIPPDYNEETLISHVSDVDAILIRTA-KLSRVVIEKAS 63
Query: 275 KLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL 454
KLKV+ R G GVDNID+++A +G+ V NAP AN + E TL+L +R ++ +AL
Sbjct: 64 KLKVIARHGIGVDNIDLEAASDRGILVTNAPFANVNAVAEHVLTLILSGSRQLIQVDSAL 123
Query: 455 KAGRWD-RALYTGSELAGKTLAILGLGRVGREVATRM-YAFGMNIIGFDPFVSADQCAQF 628
+ G ++ R G EL GKTL ++G G +G+ VA + Y GM+++ +DP+V + + +
Sbjct: 124 RNGDFEVRNRKFGIELKGKTLGVVGFGNIGQLVAEKCHYGLGMDVLVYDPYVREENVSSY 183
Query: 629 HCTKMELEDIWPLADYITLHTPLIXSTRNFINAD 730
L ++ +D +T+H P + ST + IN +
Sbjct: 184 VQLNQSLSEVLASSDIVTIHVPYLPSTHHLINEE 217
>UniRef50_Q46VE6 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding; n=6;
Proteobacteria|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding - Ralstonia
eutropha (strain JMP134) (Alcaligenes eutrophus)
Length = 312
Score = 130 bits (313), Expect = 5e-29
Identities = 71/182 (39%), Positives = 102/182 (56%), Gaps = 3/182 (1%)
Frame = +2
Query: 191 LLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPG 370
LL + DAL+VR+ TQV +L+ L+VVGR G G+DNIDV + +G+ VI A G
Sbjct: 38 LLDALAGADALIVRNRTQVDAALLERAPALRVVGRLGVGLDNIDVAACRDRGIRVIPASG 97
Query: 371 ANALSACELTCTLMLVLARHVVPASTALKAGRWDRA-LYTGSELAGKTLAILGLGRVGRE 547
ANA S E T +L R S + G+W RA L G E GKTL ++G G +GR+
Sbjct: 98 ANARSVAEYVVTTAALLLRGAYLGSAEVAGGKWPRARLSEGREALGKTLGLIGFGDIGRQ 157
Query: 548 VATRMYAFGMNIIGFDPFVSADQ--CAQFHCTKMELEDIWPLADYITLHTPLIXSTRNFI 721
A AFGM ++ DP ++ D + M L+ + +D ++LH PL+ +TR+ +
Sbjct: 158 AAALAQAFGMRVVAHDPMLAPDDPVWSATGVVCMTLDALLAQSDAVSLHVPLVAATRHLM 217
Query: 722 NA 727
NA
Sbjct: 218 NA 219
>UniRef50_A1HSQ7 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Thermosinus
carboxydivorans Nor1|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, NAD-binding - Thermosinus
carboxydivorans Nor1
Length = 317
Score = 130 bits (313), Expect = 5e-29
Identities = 73/186 (39%), Positives = 104/186 (55%), Gaps = 1/186 (0%)
Frame = +2
Query: 176 ISKEELLMEIPNHDALVVRSATQVTKEVLDAGVK-LKVVGRAGAGVDNIDVDSAGKKGVG 352
++++EL+ I DALV VT +V+ AG+ LK++ + G G + IDV +A G+
Sbjct: 37 LTEDELVELIKGMDALVA-GMDAVTAKVIAAGLPTLKIIAKHGVGYNTIDVAAAAAYGIP 95
Query: 353 VINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLG 532
V PGAN +S EL LML +ARH+ ++ G W R TGSEL GK L I+G+G
Sbjct: 96 VTITPGANNISVAELAIGLMLAVARHIPQMDGIVRRGGWSRM--TGSELYGKVLGIIGMG 153
Query: 533 RVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYITLHTPLIXSTR 712
+G EVA R +AFGM II +D D + T + + D AD+++LH P + T
Sbjct: 154 SIGCEVAKRAHAFGMKIIAYDIRPRQDMIENYGVTYLPMADCLAQADFLSLHAPALPETI 213
Query: 713 NFINAD 730
IN D
Sbjct: 214 GMINKD 219
>UniRef50_Q81T55 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=41; cellular
organisms|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase family protein - Bacillus anthracis
Length = 323
Score = 129 bits (312), Expect = 6e-29
Identities = 72/190 (37%), Positives = 106/190 (55%), Gaps = 4/190 (2%)
Frame = +2
Query: 131 ELLNAYGIATTTKAK-ISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAG 307
ELL + + K + IS +EL + + DAL+ +T+VTKEV+DA LK+V GAG
Sbjct: 16 ELLKDHDVEMYDKEELISLDELTERVKDKDALLSLLSTKVTKEVIDAAPSLKIVANYGAG 75
Query: 308 VDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKA---GRWDRA 478
DNID AG+KG+ V N P + + ELT L+L AR + T + W
Sbjct: 76 YDNIDYTYAGEKGIAVTNTPKVSTEATAELTFALLLAAARRIPEGDTLCRTTGFNGWAPL 135
Query: 479 LYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDI 658
+ G E+ GKT+ I+GLG +G+ VA R AFGMNI+ P + ++ T + LE++
Sbjct: 136 FFLGREVHGKTIGIIGLGEIGKAVAKRAKAFGMNILYTGPNRKPEAESELEATYVTLEEL 195
Query: 659 WPLADYITLH 688
AD+IT++
Sbjct: 196 LQTADFITIN 205
>UniRef50_Q6MN05 Cluster: Phosphoglycerate dehydrogenase; n=1;
Bdellovibrio bacteriovorus|Rep: Phosphoglycerate
dehydrogenase - Bdellovibrio bacteriovorus
Length = 328
Score = 129 bits (311), Expect = 8e-29
Identities = 67/212 (31%), Positives = 113/212 (53%)
Frame = +2
Query: 89 KSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDA 268
K +LI D L + ++ + L + + AL++RS T++ +E+L
Sbjct: 3 KKILITDRFAQDSFLYLQQHSQFEVVRSDNPQHLPLEHLVSAHALIIRSRTKIDEELLKK 62
Query: 269 GVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPAST 448
+L+++ +G D+ID+++ K GV V++ P AN SA +LT L+L ++ A
Sbjct: 63 ARQLQLIVTCTSGFDHIDLEATQKWGVTVMHTPTANIESAAQLTWGLVLSCVNNIQAAHK 122
Query: 449 ALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQF 628
+KAG W+R TG ELAG+ I+GLGR+G VA AFGMN++ +DP+ + +
Sbjct: 123 MVKAGEWNRDQITGIELAGRNYGIVGLGRIGSRVAELAQAFGMNVVAYDPYQEDEVFERL 182
Query: 629 HCTKMELEDIWPLADYITLHTPLIXSTRNFIN 724
H ++ E++ AD I+ H P T + +N
Sbjct: 183 HIPRLSYEEVLKTADVISFHVPKTLETEHMLN 214
>UniRef50_Q11UL6 Cluster: Phosphoglycerate dehydrogenase; n=1;
Cytophaga hutchinsonii ATCC 33406|Rep: Phosphoglycerate
dehydrogenase - Cytophaga hutchinsonii (strain ATCC
33406 / NCIMB 9469)
Length = 314
Score = 128 bits (309), Expect = 1e-28
Identities = 71/209 (33%), Positives = 117/209 (55%)
Frame = +2
Query: 98 LIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVK 277
LIVD V +LL+ IA K SKE + +P ++ LV+RS +V K+++D+ K
Sbjct: 7 LIVDDVDTALFQLLDKAAIAYDYKPDWSKETCIEALPAYEGLVIRSKFRVDKKIIDSCTK 66
Query: 278 LKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALK 457
L+ + RAGAGVDNID + +K + + +A N ++ E T L+L L ++V + T +K
Sbjct: 67 LQFIARAGAGVDNIDKEYLKEKNIALFHASEGNRVAVGEHTLGLILALINNIVRSDTEVK 126
Query: 458 AGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCT 637
W R G EL T+ ++G G +G+E + R+ AFG II +D + C +
Sbjct: 127 DAIWLREENRGYELESLTVGLIGYGNMGKETSKRLAAFGCKIIAYDKYRENYSCK--NAE 184
Query: 638 KMELEDIWPLADYITLHTPLIXSTRNFIN 724
++++E + AD I+LH PL +R +++
Sbjct: 185 QVDIEKLKAEADIISLHIPLDDFSRGWVD 213
>UniRef50_Q8XPB1 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
Clostridium perfringens|Rep: D-3-phosphoglycerate
dehydrogenase - Clostridium perfringens
Length = 301
Score = 126 bits (303), Expect = 7e-28
Identities = 75/215 (34%), Positives = 121/215 (56%), Gaps = 3/215 (1%)
Frame = +2
Query: 95 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 274
+L+ DG+ K L G T E+L +I D +V+RSAT++ +E++D +
Sbjct: 4 ILLNDGLDKKAISNLEFLGFDVDTN-HYDIEDLKEKIKKVDCIVIRSATKIRRELIDEAI 62
Query: 275 K---LKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPAS 445
K LK++ R G GVDNIDV A + G+ V N P A++ S E+ M LAR + ++
Sbjct: 63 KGGKLKLIIRGGVGVDNIDVQYAEQNGIKVRNTPNASSSSVAEIILAHMFSLARFLNQSN 122
Query: 446 TALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQ 625
+KAG W + Y G EL GKTL I+G+GR+G E+A + A GM II FD + +
Sbjct: 123 ITMKAGLWKKKDYVGVELEGKTLGIIGMGRIGSELAKKCTALGMKIIYFD--LMDIKNID 180
Query: 626 FHCTKMELEDIWPLADYITLHTPLIXSTRNFINAD 730
+ K+E +++ +D+I+++ I T++ I ++
Sbjct: 181 NNYRKVEFDELLRESDFISIN---ISGTKSIIGSE 212
>UniRef50_Q0ETU3 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Thermoanaerobacter
ethanolicus X514|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Thermoanaerobacter
ethanolicus X514
Length = 324
Score = 126 bits (303), Expect = 7e-28
Identities = 69/218 (31%), Positives = 122/218 (55%), Gaps = 2/218 (0%)
Frame = +2
Query: 86 IKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLD 265
+K VL+ + + + +LL T S++ L+ + + DA+++R+ +++T+EV++
Sbjct: 1 MKKVLLSEEIHPEGRKLLEGK-FEIVTAPDTSQQTLISMVKDVDAIILRTRSKITREVIE 59
Query: 266 AGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPAS 445
LK++ R GAGVDNIDV++A +KG+ V N P N LS E T ++L L++ +
Sbjct: 60 NAPHLKIISRTGAGVDNIDVNAATEKGILVCNLPAVNNLSVAEHTIAMILNLSKQLSLMD 119
Query: 446 TALKAGRWD-RALYTGSELAGKTLAILGLGRVGREVATRMY-AFGMNIIGFDPFVSADQC 619
A+++G W R E+ GK L I+G+G +G VA + + GM I+ +DP+V
Sbjct: 120 KAVRSGNWGARNSNISVEIEGKVLGIVGMGNIGSLVAKKCHDGLGMKIVAYDPYVKEKFR 179
Query: 620 AQFHCTKMELEDIWPLADYITLHTPLIXSTRNFINADV 733
+ E+++ +D++TLH P I TR I ++
Sbjct: 180 GYDYKFVDTREELFKESDFVTLHCPDIPETRGMITREL 217
>UniRef50_A6Q7Q2 Cluster: D-3-phosphoglycerate dehydrogenase; n=27;
Epsilonproteobacteria|Rep: D-3-phosphoglycerate
dehydrogenase - Sulfurovum sp. (strain NBC37-1)
Length = 529
Score = 125 bits (302), Expect = 1e-27
Identities = 77/219 (35%), Positives = 113/219 (51%), Gaps = 5/219 (2%)
Frame = +2
Query: 89 KSVLIVDGVGAKCAELL-NAYGIATTTKAKISKEELLMEI-PNHDALVVRSATQVTKEVL 262
K++++ D + ++L N I A K++L+ EI P D + RS+T V L
Sbjct: 4 KTIVVCDHIHQSGLDILANDSEIKLINAADEPKDKLIAEIIPLADVAITRSSTDVDAAFL 63
Query: 263 DAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPA 442
++ K+ + RAG GVDN+D+ + K+G+ V+N P AN ++A ELT ML R A
Sbjct: 64 ESAKKITAIVRAGVGVDNVDIPGSSKQGIVVMNVPTANTIAAVELTLAHMLSCVRQFPYA 123
Query: 443 STALKAGR-WDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQC 619
LK R W R + G+EL K L I+G G +G V R AF M+++ +DP++ +
Sbjct: 124 HNNLKLDRVWRRQDWYGTELKDKKLGIIGFGNIGSRVGKRAKAFEMDVLAYDPYIDPSKA 183
Query: 620 AQFHC--TKMELEDIWPLADYITLHTPLIXSTRNFINAD 730
TK EDI D IT+HTP T IN D
Sbjct: 184 TDLDIGYTK-NFEDIL-ACDIITIHTPKTEETIGMINKD 220
>UniRef50_Q9WYG2 Cluster: Phosphoglycerate dehydrogenase, putative;
n=2; Thermotoga|Rep: Phosphoglycerate dehydrogenase,
putative - Thermotoga maritima
Length = 327
Score = 124 bits (300), Expect = 2e-27
Identities = 68/171 (39%), Positives = 103/171 (60%), Gaps = 2/171 (1%)
Frame = +2
Query: 215 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 394
DAL+V VT E+++ LK++ + G GVDNID+++A KKG+ V GAN+LS E
Sbjct: 44 DALIV-GTHPVTAEMVENS-SLKIIAKHGVGVDNIDLEAATKKGIPVTITAGANSLSVAE 101
Query: 395 LTCTLMLVLARHVVPASTAL-KAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAF 571
LT + L+R +V A L RW+ + G E++GKTL ++G G +GREV +
Sbjct: 102 LTIAFIFALSRGLVWAHNKLFLERRWEGTV--GQEVSGKTLGVVGFGSIGREVVKKAVCL 159
Query: 572 GMNIIGFDPFVSADQCAQFHCTKM-ELEDIWPLADYITLHTPLIXSTRNFI 721
GMN++ +DP+VS D T + +LE + +D+++LH PL ST+N I
Sbjct: 160 GMNVLVYDPYVSKDSVRLLEATPVDDLEQLLKESDFVSLHVPLNESTKNMI 210
>UniRef50_Q8UJZ6 Cluster: Phosphoglycerate dehydrogenase; n=3;
Alphaproteobacteria|Rep: Phosphoglycerate dehydrogenase
- Agrobacterium tumefaciens (strain C58 / ATCC 33970)
Length = 354
Score = 124 bits (299), Expect = 2e-27
Identities = 58/169 (34%), Positives = 101/169 (59%), Gaps = 1/169 (0%)
Frame = +2
Query: 221 LVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELT 400
+VVR + ++ + A L+V+ + G GVDNIDVD+A ++ + V+ A GANALS E
Sbjct: 76 VVVRMG-RFSEAAIKAAPSLRVLSKHGVGVDNIDVDAASRREIPVVVAAGANALSVAEHA 134
Query: 401 CTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMN 580
TL+ + + +VP + ++AGRW++A Y+G ELAG + ++G G + R+ A FG+
Sbjct: 135 ITLLFAVVKRIVPLDSGIRAGRWEKAGYSGKELAGMIIGLVGFGAIARQTAVFARGFGLK 194
Query: 581 IIGFDPFVSADQCAQFHCTKM-ELEDIWPLADYITLHTPLIXSTRNFIN 724
+ +DPF + ++ +++D+ +D ++LH PL TRN ++
Sbjct: 195 VQAYDPFTDETAFVEAGVHRVADVDDLISSSDILSLHCPLTPDTRNLLD 243
>UniRef50_A4YUP8 Cluster: Putative D-3-phosphoglycerate
dehydrogenase; n=1; Bradyrhizobium sp. ORS278|Rep:
Putative D-3-phosphoglycerate dehydrogenase -
Bradyrhizobium sp. (strain ORS278)
Length = 335
Score = 124 bits (299), Expect = 2e-27
Identities = 70/221 (31%), Positives = 115/221 (52%), Gaps = 5/221 (2%)
Frame = +2
Query: 83 DIKSVLIVDG--VGAKCAELLNAYGIATTTKAKISKEELLMEIPNH---DALVVRSATQV 247
D++ L++ G + A+ + G A + + + L EI D ++VR ++
Sbjct: 9 DMRYKLLITGPALTAEATAIAARRGAALVDNPRYASPQELAEITAREQPDGIIVRQG-KI 67
Query: 248 TKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLAR 427
+V+ A KLK + + G G DNIDV++A ++G+ V A GAN+ S EL LM +AR
Sbjct: 68 DDQVIGASQKLKAIAKHGVGYDNIDVEAADRRGIPVFVARGANSQSVAELAFALMFAVAR 127
Query: 428 HVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVS 607
+ +K G WD+A G++L G++L ++G G +GR + + M + FDP++
Sbjct: 128 EIPHLDARIKTGHWDKATTKGAQLLGRSLGVIGFGEIGRILVGLVQPLHMEVRIFDPYMP 187
Query: 608 ADQCAQFHCTKMELEDIWPLADYITLHTPLIXSTRNFINAD 730
AD L++I +D I+LH PL+ TRN I D
Sbjct: 188 ADAEISGAERAGSLDEILTASDVISLHCPLMPQTRNMIGRD 228
>UniRef50_A1AR04 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Pelobacter propionicus
DSM 2379|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Pelobacter propionicus
(strain DSM 2379)
Length = 357
Score = 123 bits (297), Expect = 4e-27
Identities = 71/221 (32%), Positives = 121/221 (54%), Gaps = 4/221 (1%)
Frame = +2
Query: 80 VDIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEV 259
V +VLI + + E L S+E L I + +ALV RS +V+ ++
Sbjct: 20 VHTMNVLIASSIDGEAIERLEQEHQVIRAFPNSSEESLHALIRDCEALVFRSGIRVSADL 79
Query: 260 LDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVP 439
+ +LK++ RAG+G+DN+DV+ A K+GV ++ P +A + E+ ML L+R ++
Sbjct: 80 MGCAPRLKLLVRAGSGMDNLDVEYARKRGVQLVRIPQPSARAVAEMAFAFMLALSRRLLE 139
Query: 440 ASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQC 619
A +++ GRW++ ++G L KTL ++G+G G VA A+GM +IG S ++
Sbjct: 140 ADRSMRNGRWEKHEFSGYLLRDKTLGVVGIGNTGSCVAQMGVAWGMRVIGCVQHPSRERE 199
Query: 620 AQFHCTK----MELEDIWPLADYITLHTPLIXSTRNFINAD 730
F C K +E + + ADY+++H PL +TR ++AD
Sbjct: 200 EGF-CEKGIQMLEFDQVIANADYLSIHVPLKDNTRRLLDAD 239
>UniRef50_Q18XF4 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=2; Desulfitobacterium
hafniense|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Desulfitobacterium
hafniense (strain DCB-2)
Length = 320
Score = 122 bits (294), Expect = 9e-27
Identities = 64/161 (39%), Positives = 95/161 (59%)
Frame = +2
Query: 242 QVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVL 421
+V E L+A LK++ + G GVD+ID+ +A +G+ V NAPG NA S +L ML L
Sbjct: 61 KVYAEDLEAAPNLKLIIKHGTGVDSIDLKAAAARGITVANAPGTNANSVADLAFGFMLSL 120
Query: 422 ARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPF 601
AR +V A + G W + G ++ GKTL +LGLG++G+ V R F MNI+G+D
Sbjct: 121 ARQIVSADKRTRDGFWGTVM--GKDVYGKTLGVLGLGQIGKGVIRRASGFDMNILGYDLV 178
Query: 602 VSADQCAQFHCTKMELEDIWPLADYITLHTPLIXSTRNFIN 724
+ ++ LE+I ADYI++H PL+ ST+N I+
Sbjct: 179 HHSQFEKEYRVRAATLEEIMSEADYISVHLPLLESTKNIID 219
>UniRef50_A7HM61 Cluster: Glyoxylate reductase; n=1;
Fervidobacterium nodosum Rt17-B1|Rep: Glyoxylate
reductase - Fervidobacterium nodosum Rt17-B1
Length = 317
Score = 121 bits (292), Expect = 2e-26
Identities = 59/189 (31%), Positives = 110/189 (58%), Gaps = 4/189 (2%)
Frame = +2
Query: 176 ISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGV 355
+SKEE++ DA+V + + KE + + K K++ G +NID+++A ++G+ V
Sbjct: 32 LSKEEMIKRAEYADAIVTQLRDPIDKEFIYSLKKAKIIANYAVGYNNIDIEAAKERGIYV 91
Query: 356 INAPGANALSACELTCTLMLVLARHVVPASTALKAGR---WDRALYTGSELAGKTLAILG 526
N PG + ++ L+L +AR +V + ++ G+ W L+ G +L GKTL ++G
Sbjct: 92 TNTPGVLTEATADIAFALILAVARRIVESDKFVREGKFVGWKPKLFLGYDLYGKTLGVIG 151
Query: 527 LGRVGREVATRMYAFGMNIIGFDPFVSADQC-AQFHCTKMELEDIWPLADYITLHTPLIX 703
+GR+G+ VA R FGMNI+ ++ ++ Q++ + ++++ ++DYI+LHTPL
Sbjct: 152 MGRIGQAVARRALGFGMNIVYYNRNRLPEEIEKQYNAKYVNIDELVEISDYISLHTPLTK 211
Query: 704 STRNFINAD 730
T + IN +
Sbjct: 212 ETYHLINKE 220
>UniRef50_A0V9Y4 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=2; Comamonadaceae|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Delftia acidovorans SPH-1
Length = 354
Score = 120 bits (289), Expect = 4e-26
Identities = 69/176 (39%), Positives = 102/176 (57%), Gaps = 5/176 (2%)
Frame = +2
Query: 215 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 394
DA++ R+AT ++ + A LKV+ + G GV NIDV +A ++G+ V PGANA S E
Sbjct: 75 DAVISRTAT-LSAAAIAACPTLKVISKHGVGVSNIDVAAASQRGIPVYVTPGANAQSVAE 133
Query: 395 LTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFG 574
+T LM AR + L+AGRW RA G EL+G+TL +LG G+VG+ VA A G
Sbjct: 134 MTLGLMFAAARRIAWMDAELRAGRWSRA-QDGLELSGRTLGLLGFGQVGQRVARVALALG 192
Query: 575 MNIIGFDPF---VSADQCAQFHCTKM--ELEDIWPLADYITLHTPLIXSTRNFINA 727
M ++ FDP A +M ++++ PL+D ++LH PL TR+ ++A
Sbjct: 193 MQVVAFDPAFDPACAPGPGAVAGVRMLGSVDELLPLSDVLSLHLPLNARTRHLLDA 248
>UniRef50_A0UAW1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=14; Burkholderiales|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Burkholderia multivorans ATCC 17616
Length = 452
Score = 120 bits (289), Expect = 4e-26
Identities = 64/216 (29%), Positives = 111/216 (51%), Gaps = 2/216 (0%)
Frame = +2
Query: 89 KSVLIVDG--VGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVL 262
K V++V + + E+L + + K + + + + + ++ ++ V+
Sbjct: 144 KPVVLVTAADLAPQALEMLAQFDVVFAGKQPTEDDIVALCVKHKPVAIIVRYGKINARVM 203
Query: 263 DAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPA 442
DA L+V+ + G+G+D ID D+A +G+ V A GANA + E L+L A+ V
Sbjct: 204 DAAENLQVISKHGSGIDVIDQDAAAARGIAVRAAVGANAAAVAEHAWALILACAKSVPQL 263
Query: 443 STALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCA 622
++ G WD+A + EL G+TL ++GLG +GR VA AFGM ++ FDPF A
Sbjct: 264 DMRMREGHWDKATHKSVELDGRTLGLVGLGAIGRRVAAIGVAFGMKVLAFDPFAKE---A 320
Query: 623 QFHCTKMELEDIWPLADYITLHTPLIXSTRNFINAD 730
T + L+ ++ +D +++H PL R +N D
Sbjct: 321 PAGVTLVPLDTLYAESDVVSMHCPLTADNRRMLNRD 356
>UniRef50_Q3SK87 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase; n=4; Proteobacteria|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase - Thiobacillus
denitrificans (strain ATCC 25259)
Length = 391
Score = 119 bits (287), Expect = 6e-26
Identities = 73/218 (33%), Positives = 119/218 (54%), Gaps = 15/218 (6%)
Frame = +2
Query: 119 AKCAELLNAYGIATTTKAKISKEELLM-EIPNHDALVVRSATQVTKEVLDAGVKLKVVGR 295
A+ ++L I+ A++ + ++ ++ + DA++VRSA E+ + +GR
Sbjct: 2 AEARKILTLNAISARGLARLPEHYVVGGDLADPDAILVRSANMHEMEI---PTSVCAIGR 58
Query: 296 AGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPA----------- 442
AGAG +NI V ++G+ V NAPGANA + EL ML+ AR++VPA
Sbjct: 59 AGAGTNNIPVKKMSERGLPVFNAPGANANAVKELVIAGMLMGARNLVPALKFVESLDGTD 118
Query: 443 STALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCA 622
KA + + G EL G+TL ++GLG +G +A GMN++G+DP ++ D
Sbjct: 119 EAMHKATEAGKKQFAGMELPGRTLGVIGLGAIGSHIAEAAIRLGMNVVGYDPAITVDAAW 178
Query: 623 QF--HCTKME-LEDIWPLADYITLHTPLIXSTRNFINA 727
+ + E ++D+ AD++TLH PL+ +TRN INA
Sbjct: 179 RLPSQVKRAENVDDVLRTADFVTLHVPLLDATRNLINA 216
>UniRef50_A7HEG1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=4; Bacteria|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase NAD-binding -
Anaeromyxobacter sp. Fw109-5
Length = 399
Score = 119 bits (287), Expect = 6e-26
Identities = 69/215 (32%), Positives = 115/215 (53%), Gaps = 2/215 (0%)
Frame = +2
Query: 95 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 274
+L+ D + A G+ + ++ +EL + LVVRS QV +V DA
Sbjct: 3 ILVADAFPTERLADFQALGLEVAHRPDVAVQELAAAARDAAILVVRSK-QVQADVFDAAP 61
Query: 275 KLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL 454
L +V RAGAGV+ IDV +A ++GV V N PG N+++ EL L++ L R + L
Sbjct: 62 GLSLVVRAGAGVNTIDVAAASRRGVYVANCPGQNSIAVAELAIGLVVALDRRIPDNVALL 121
Query: 455 KAGRWDRALYTGSE-LAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFH 631
+AG+WD+ ++ ++ L G+TL + G+G +GREVA R A GM ++ + + Q
Sbjct: 122 RAGKWDKKTFSEAQGLYGRTLGVAGVGSIGREVARRAQALGMRVVAWSRSLDDRQAKLLG 181
Query: 632 CTKM-ELEDIWPLADYITLHTPLIXSTRNFINADV 733
+ +L + +D+++LH L TR ++ +V
Sbjct: 182 VERAPDLAALARESDFLSLHLALSKETRGIVSREV 216
>UniRef50_A4WXD4 Cluster: Dimethylmenaquinone methyltransferase;
n=1; Rhodobacter sphaeroides ATCC 17025|Rep:
Dimethylmenaquinone methyltransferase - Rhodobacter
sphaeroides ATCC 17025
Length = 334
Score = 119 bits (287), Expect = 6e-26
Identities = 59/171 (34%), Positives = 96/171 (56%)
Frame = +2
Query: 215 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 394
DA++VR ++T EV+ A LKV+ + G GVDNID+ +A +G+ V+ + G+N+ + E
Sbjct: 58 DAMMVRQG-RITDEVIGASPGLKVIVKHGVGVDNIDLAAAEARGIPVLRSMGSNSRAVAE 116
Query: 395 LTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFG 574
L L+L + + P + A+K G W + + G + G L ++G G +GRE A A G
Sbjct: 117 HAIALALMLVKEIQPLNAAVKGGAWPKPTFIGKDFQGAMLGLVGYGGIGRETARMAEALG 176
Query: 575 MNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYITLHTPLIXSTRNFINA 727
M ++ DP+ A +LE + P D ++LH PL +TR+ I+A
Sbjct: 177 MEVVVHDPYAPEAAEADGFAAAADLEAMLPALDILSLHCPLTSATRDLIDA 227
>UniRef50_A4YFM2 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Metallosphaera sedula
DSM 5348|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Metallosphaera sedula DSM
5348
Length = 324
Score = 119 bits (287), Expect = 6e-26
Identities = 67/225 (29%), Positives = 124/225 (55%), Gaps = 5/225 (2%)
Frame = +2
Query: 71 KMVVDIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVT 250
K VV I S +IV+ + + LN+ +++++ + + A+V R A +++
Sbjct: 2 KPVVGIDSSVIVEELDQEKVRELNSLAEIVYFNPYAPEDQIVSLLRDAIAIVDRKA-KIS 60
Query: 251 KEVLDAGVKLKVVGRAGAGVDN--IDVDSAGKKGVGVINAPGANALSACELTCTLMLVLA 424
+++ LK++ R GAGVD +D+ +A ++ + + PG N+++ ELT L + L
Sbjct: 61 SKIIRELRNLKLIARTGAGVDETRVDLKAAKERDIIITYNPGGNSVAVAELTIMLAIALY 120
Query: 425 RHVVPASTALKAGRWDRAL---YTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFD 595
R V+P + ++KAG+W G EL GK ILG G +G+ VA + + ++G+D
Sbjct: 121 RKVIPLALSVKAGKWSELKPKDTMGHELEGKAWGILGFGNIGKRVAQLVTSLNCKVLGYD 180
Query: 596 PFVSADQCAQFHCTKMELEDIWPLADYITLHTPLIXSTRNFINAD 730
P+VS++ + + LE++ +D I++H PL STR+ IN++
Sbjct: 181 PYVSSEIMEKHGVKSLSLEELLSKSDIISIHVPLTESTRHLINSE 225
>UniRef50_Q6W1I8 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Rhizobium sp. NGR234|Rep: D-3-phosphoglycerate
dehydrogenase - Rhizobium sp. (strain NGR234)
Length = 327
Score = 118 bits (284), Expect = 1e-25
Identities = 69/182 (37%), Positives = 102/182 (56%), Gaps = 1/182 (0%)
Frame = +2
Query: 185 EELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINA 364
+EL + + DA +V S T+EVL LKV+ R G G D+ID D+A + GVG+
Sbjct: 41 DELATLLEDCDAAIV-STDPFTREVLAGDRNLKVIARVGVGTDSIDHDAAKEFGVGISVT 99
Query: 365 PGANALSACELTCTLMLVLARHVVPASTALKAGRWDR-ALYTGSELAGKTLAILGLGRVG 541
PG NA + + T ++L L R VV A+KAGRWDR T +EL KT+ ++G G +G
Sbjct: 100 PGMNAETVADQTLAMILGLMRRVVTQDQAVKAGRWDRVGEATPTELYRKTVGLIGAGIIG 159
Query: 542 REVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYITLHTPLIXSTRNFI 721
+ V R+ FG+ ++ FD V A+ C L+ + +D ++LH PL+ TR +
Sbjct: 160 KAVIRRLLGFGVRVLYFDAMVEKVHGAE-RCG--SLDQLLGSSDIVSLHAPLLADTRELM 216
Query: 722 NA 727
NA
Sbjct: 217 NA 218
>UniRef50_Q4WHR3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Aspergillus fumigatus|Rep: D-3-phosphoglycerate
dehydrogenase - Aspergillus fumigatus (Sartorya
fumigata)
Length = 635
Score = 118 bits (284), Expect = 1e-25
Identities = 88/262 (33%), Positives = 132/262 (50%), Gaps = 52/262 (19%)
Frame = +2
Query: 95 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 274
VL+ + + LL A + + + +ELL IP ++ALVVRS T+VT +L A
Sbjct: 11 VLVPEKLSPDGLALLRA-SLEVDERRGLDADELLQIIPEYEALVVRSETKVTANLLRAAK 69
Query: 275 KLKVVGRAGAGVDNI------------------------DVDSAGKKGVGVINAPGANAL 382
+LKVV RAG GVDN+ DV+ A K G+ V+N+P N
Sbjct: 70 QLKVVARAGVGVDNVGELAQPPLPPSPSLGSWPLTSHRTDVEEATKLGIVVVNSPSGNIG 129
Query: 383 SACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGL---------GR 535
+A E T L++ +AR++ A ++LK+G+W+R+ + G E+ GKTL+I+GL GR
Sbjct: 130 AAAEHTIALLMAMARNIPEACSSLKSGKWERSKFVGVEVKGKTLSIIGLGKGELLAIWGR 189
Query: 536 ------------------VGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKME-LEDI 658
VG VA GM++ DP+ S A T + L ++
Sbjct: 190 GIHFRYDGGSSGWADRQTVGLTVARLAKGLGMHVNALDPYASPAVAASASVTLVSSLSEL 249
Query: 659 WPLADYITLHTPLIXSTRNFIN 724
P AD++T+HTPLI ST+ I+
Sbjct: 250 LPTADFLTIHTPLIASTKGMIS 271
>UniRef50_Q5V1E2 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Haloarcula marismortui|Rep: D-3-phosphoglycerate
dehydrogenase - Haloarcula marismortui (Halobacterium
marismortui)
Length = 323
Score = 118 bits (283), Expect = 2e-25
Identities = 68/206 (33%), Positives = 103/206 (50%), Gaps = 1/206 (0%)
Frame = +2
Query: 116 GAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGR 295
G A +L+A T A E + + DAL+V + TQVT EV++A LKVVGR
Sbjct: 15 GETRAAVLDAVDATVETIAAKEPEAVARAVDGADALIVDAGTQVTAEVIEAADSLKVVGR 74
Query: 296 AGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDR 475
AG G+DNI V +A GV V+N P + T LML R + ++K G W
Sbjct: 75 AGIGMDNIAVRAAVAAGVTVVNVPDYSVEEVSTHTFALMLACLRRIPTFDRSVKRGEWKW 134
Query: 476 AL-YTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELE 652
A+ LAG T+ ++ G++ A ++ F +++I +DP+ + + LE
Sbjct: 135 AVGQPIRRLAGSTVGLVAFGKLASRFAAKLRGFDIDVIAYDPYAPEYRMGDLGVESVTLE 194
Query: 653 DIWPLADYITLHTPLIXSTRNFINAD 730
+ +D ++LH PL TR I+AD
Sbjct: 195 TLLGDSDIVSLHAPLTDETRGMIDAD 220
>UniRef50_Q5WLJ2 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Bacillus|Rep: D-3-phosphoglycerate dehydrogenase -
Bacillus clausii (strain KSM-K16)
Length = 316
Score = 117 bits (282), Expect = 3e-25
Identities = 61/182 (33%), Positives = 103/182 (56%)
Frame = +2
Query: 176 ISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGV 355
IS+ ++E A +V + ++ VL LK++ + G GVDNIDVD+A K GV V
Sbjct: 35 ISQSAFVLEARGAQAAIV-AFNEIHDAVLAQLPDLKIIAKHGVGVDNIDVDAAKKHGVTV 93
Query: 356 INAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGR 535
N P AN + + +L+L LAR + + K G+W +L+ G+++ +TL I+GLG
Sbjct: 94 TNVPNANKHAVADFAFSLLLSLARQIPTGNEKTKKGKWP-SLF-GADVYQQTLGIIGLGA 151
Query: 536 VGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYITLHTPLIXSTRN 715
+G+EVA R F M ++ +DP++ + + L+ + +D++T+H PL+ TR+
Sbjct: 152 IGKEVARRASGFSMTVLAYDPYIDRTYARKNGIEAVSLDALLQQSDFVTIHIPLLPETRH 211
Query: 716 FI 721
I
Sbjct: 212 LI 213
>UniRef50_A2A023 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Flexibacteraceae|Rep: D-3-phosphoglycerate dehydrogenase
- Microscilla marina ATCC 23134
Length = 316
Score = 117 bits (282), Expect = 3e-25
Identities = 64/214 (29%), Positives = 119/214 (55%), Gaps = 1/214 (0%)
Frame = +2
Query: 92 SVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAG 271
++LI+D + LL + GI + I++ E+L + ++ L+VRS T + ++++
Sbjct: 4 NILIIDKMHPSITSLLESRGIQGDYRPDITRAEILTIVDKYEGLMVRSKTAIDEDLIGRA 63
Query: 272 VKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTA 451
+LKV+ RAGAG+D ID+ +A +G+ V+NAP N + E T ++L L +V A
Sbjct: 64 SRLKVIARAGAGLDKIDLSAANARGIKVLNAPEGNRDAVGEQTIGMLLSLLHNVQRADWE 123
Query: 452 LKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFG-MNIIGFDPFVSADQCAQF 628
+K W R G EL K + ++G G +G+ A R+ +FG ++I +D D+ ++
Sbjct: 124 VKNFAWKREANRGVELMDKVVGVIGYGNMGKAFAKRLSSFGCKDVIAYDR--RPDRGDEY 181
Query: 629 HCTKMELEDIWPLADYITLHTPLIXSTRNFINAD 730
++ +++++ A+ I+LH PL T ++ D
Sbjct: 182 -ARQVSMDEVFERAEIISLHVPLDEYTYELVDDD 214
>UniRef50_Q7X388 Cluster: Phosphoglycerate dehydrogenase; n=3;
Escherichia coli|Rep: Phosphoglycerate dehydrogenase -
Escherichia coli
Length = 306
Score = 117 bits (281), Expect = 3e-25
Identities = 67/187 (35%), Positives = 107/187 (57%)
Frame = +2
Query: 173 KISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVG 352
+ SKEEL+ +I + +A++ + +++EV+D LKV+ + G G+DNIDVD A K +
Sbjct: 37 RYSKEELIEKIKDANAIITGN-DPLSREVIDQAKNLKVISKYGVGLDNIDVDYANSKDIV 95
Query: 353 VINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLG 532
V A AN++S E+T +ML +R V + + G+ R + G EL K L ++GLG
Sbjct: 96 VHKALNANSISVAEMTILMMLSSSRKYVEIESQARNGKDIRLV--GYELYQKNLGLIGLG 153
Query: 533 RVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYITLHTPLIXSTR 712
+G+ VA ++ GM I DP + + + K ++I+ +D I+LH PL+ STR
Sbjct: 154 AIGQHVAHIAHSMGMTITAHDPHIDKSKVPSYIELKSP-DEIYQYSDVISLHLPLLDSTR 212
Query: 713 NFINADV 733
N IN V
Sbjct: 213 NIINDSV 219
>UniRef50_A7CY19 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=1; Opitutaceae bacterium
TAV2|Rep: D-isomer specific 2-hydroxyacid dehydrogenase
NAD-binding - Opitutaceae bacterium TAV2
Length = 318
Score = 116 bits (280), Expect = 5e-25
Identities = 64/163 (39%), Positives = 97/163 (59%), Gaps = 2/163 (1%)
Frame = +2
Query: 245 VTKEVLDAGV-KLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVL 421
+T V+D + +LKV+ + G G+D IDV A K + V+ PG N + E T L+L L
Sbjct: 58 ITAAVIDKSLPRLKVISKYGIGLDKIDVAHATSKKIPVLFTPGVNHTTVAEHTFLLLLAL 117
Query: 422 ARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPF 601
++++ + + ++G W R TG EL KT+ I+GLGR+G+EVA R AFGM +I +D +
Sbjct: 118 EKNILFHTDSTRSGGWKRK--TGHELLAKTIGIVGLGRIGKEVAIRARAFGMEVIAYDIY 175
Query: 602 VSADQCAQFHCTKMEL-EDIWPLADYITLHTPLIXSTRNFINA 727
Q + ++ E+I+ ADYI+LHT L TR+ INA
Sbjct: 176 WDEAFAKQHNVKRVATKEEIFTSADYISLHTNLTPETRDMINA 218
>UniRef50_A0LN07 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Syntrophobacter
fumaroxidans MPOB|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Syntrophobacter
fumaroxidans (strain DSM 10017 / MPOB)
Length = 317
Score = 116 bits (280), Expect = 5e-25
Identities = 65/213 (30%), Positives = 119/213 (55%), Gaps = 2/213 (0%)
Frame = +2
Query: 95 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 274
+L+ + + A+ E+L A + ++ L+ + + D +++R+ VT+ ++++
Sbjct: 7 ILLYESMHARGTEVL-AEKCELVYATSLDEKNLIAQAADVDGIIIRANGAVTRALIESAP 65
Query: 275 KLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL 454
+LKV+GR G G+D ID+ A ++GV V+ P AN S E + ++LA+ + AL
Sbjct: 66 RLKVIGRHGVGLDAIDLRCAKERGVKVVFTPTANTESVAEHFVGMAIMLAKMIRTGDIAL 125
Query: 455 KAGRW-DRALYTGSELAGKTLAILGLGRVGREVA-TRMYAFGMNIIGFDPFVSADQCAQF 628
+ G W R G+EL GK L +LG GR+GR+ A F MN+I +D +
Sbjct: 126 RTGDWAARNRLIGTELHGKALGVLGFGRIGRQTARICRNGFAMNVIYYDVCDYPAVEKEL 185
Query: 629 HCTKMELEDIWPLADYITLHTPLIXSTRNFINA 727
++ E+++ +D+I+++ PL+ STR+F+NA
Sbjct: 186 QAKRVSGEEVFEQSDFISVNLPLLPSTRHFVNA 218
>UniRef50_Q0RXU8 Cluster: Phosphoglycerate dehydrogenase; n=1;
Rhodococcus sp. RHA1|Rep: Phosphoglycerate dehydrogenase
- Rhodococcus sp. (strain RHA1)
Length = 325
Score = 116 bits (279), Expect = 6e-25
Identities = 74/217 (34%), Positives = 109/217 (50%), Gaps = 1/217 (0%)
Frame = +2
Query: 86 IKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLD 265
I +V+ D G +L + I A +E+LL ALVVR+ TQV +++++
Sbjct: 8 IDAVITEDVWGRAFNDLGTSRSILRAPHAWQDREKLLELGSRSRALVVRNRTQVDRQLIE 67
Query: 266 AGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPAS 445
A L+V+ RAG G+DNIDV A + GV V+ GANA+S E T + L R V
Sbjct: 68 ACPSLRVIARAGVGLDNIDVKCANEAGVVVVAPLGANAISVAEHTIGMALAAVRRTVELD 127
Query: 446 TALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQ 625
+ G W+R G EL G +LG G GR A + GM+I+ +DPF A++ AQ
Sbjct: 128 ADCRRGGWERT--PGRELHGGVWGLLGAGATGRACARLARSLGMSIVAYDPFADAEKLAQ 185
Query: 626 FHCTKMELED-IWPLADYITLHTPLIXSTRNFINADV 733
+E + AD ++ H P T + IN ++
Sbjct: 186 EGIELVEHPALVAARADVMSCHLPATRGTAHLINGEL 222
>UniRef50_A4FHH0 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Saccharopolyspora erythraea NRRL 2338|Rep:
D-3-phosphoglycerate dehydrogenase - Saccharopolyspora
erythraea (strain NRRL 23338)
Length = 336
Score = 116 bits (279), Expect = 6e-25
Identities = 74/219 (33%), Positives = 116/219 (52%), Gaps = 6/219 (2%)
Frame = +2
Query: 95 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 274
VL+ D A+ L +G + + E+L + + LVVRS T V V++A
Sbjct: 3 VLLADAFPAEHVSALTEHGHDCDYQPDTTTEQLPDRLTGREVLVVRS-TAVPSAVIEAAD 61
Query: 275 KLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL 454
L++V RAG+G + ID +SA ++GV V N PG NA++ EL LML L R V L
Sbjct: 62 SLRLVIRAGSGTNTIDCESAAERGVHVCNVPGRNAIAVAELAFALMLALDRSVCDNVDDL 121
Query: 455 KAGRWDRALYTGSE-LAGKTLAILGLGRVGREVATRMYAFGMNIIGF-DPFVSADQCAQF 628
+AGRWD+ Y+ + + G+ + ++GLG++G A R AFG + P S +
Sbjct: 122 RAGRWDKKRYSRARGIHGRRVGVVGLGQIGLAFAERAAAFGATVHAVAKPGRSPKTAERA 181
Query: 629 HCTKME-LEDIWPLA---DYITLHTPLIXSTRNFINADV 733
+ ++D+ LA D ++LH P +TRN ++AD+
Sbjct: 182 DAIGIRFVDDLTTLARTCDVLSLHVPATSATRNLVDADL 220
>UniRef50_Q21A61 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Rhodopseudomonas
palustris BisB18|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Rhodopseudomonas palustris
(strain BisB18)
Length = 321
Score = 116 bits (278), Expect = 8e-25
Identities = 61/170 (35%), Positives = 96/170 (56%), Gaps = 1/170 (0%)
Frame = +2
Query: 215 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 394
DA++VR ++ +++ A LKVV + GAG ++ID+ +A GV V+ A GANA S E
Sbjct: 49 DAIIVRLVERIDADLMKASPNLKVVAKHGAGTNDIDLAAAKALGVPVLAAVGANAHSVAE 108
Query: 395 LTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFG 574
LML L + V ++ G WD+ Y G EL G+ L ++G+G +GR +A + G
Sbjct: 109 HAFMLMLALIKDVRNQDAYVRGGGWDKKGYRGRELRGRVLGLVGIGMIGRALAAMVQPIG 168
Query: 575 MNIIGFDPFVSADQCAQFHCTKME-LEDIWPLADYITLHTPLIXSTRNFI 721
M I +DPF A H +++ L+++ +D ++LH PL T+N I
Sbjct: 169 MTTIAYDPFAPAAAFGP-HARRVDSLDELLAQSDVVSLHCPLTPQTQNLI 217
>UniRef50_Q03YV3 Cluster: Lactate dehydrogenase related enzyme; n=1;
Leuconostoc mesenteroides subsp. mesenteroides ATCC
8293|Rep: Lactate dehydrogenase related enzyme -
Leuconostoc mesenteroides subsp. mesenteroides (strain
ATCC 8293 /NCDO 523)
Length = 314
Score = 115 bits (277), Expect = 1e-24
Identities = 63/215 (29%), Positives = 115/215 (53%), Gaps = 1/215 (0%)
Frame = +2
Query: 89 KSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDA 268
K V + D + A ++L G+ + E++ E A+++ + +++DA
Sbjct: 3 KQVFLPDDIPAVGKKILEEAGLEVVVGSGRDHEKMKAEGVEASAVLI-GTQKFDADIMDA 61
Query: 269 GVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPAST 448
LKV+ R G G D +DVD+A ++G+ V+N P A + S E + +L +++++ S
Sbjct: 62 MPNLKVIARNGVGYDAVDVDAATQRGIYVVNTPKALSGSVAETAVSELLAISKNLYQDSK 121
Query: 449 ALKAGRWD-RALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQ 625
A+ W+ R + G ++ GKT+ ILG GR+G++VA ++ F + +I FDPF +
Sbjct: 122 AIHDDNWNYRKAHPGRDIEGKTVGILGFGRIGQQVAKKLSGFDVKVIAFDPFAKDVPGVE 181
Query: 626 FHCTKMELEDIWPLADYITLHTPLIXSTRNFINAD 730
++ E I+ ADY+ +H P + T++ I AD
Sbjct: 182 L----VDRETIFKTADYVMVHLPALPETQHSIGAD 212
>UniRef50_Q65WI5 Cluster: SerA protein; n=1; Mannheimia
succiniciproducens MBEL55E|Rep: SerA protein -
Mannheimia succiniciproducens (strain MBEL55E)
Length = 326
Score = 115 bits (276), Expect = 1e-24
Identities = 72/206 (34%), Positives = 114/206 (55%), Gaps = 4/206 (1%)
Frame = +2
Query: 116 GAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGR 295
G K E NA +A T + + +L E+ + + L++R + + +E + LKV+GR
Sbjct: 15 GMKVLEDANAQ-VAITNDG--NPKIMLPELLDAEGLIIRIGS-IDRETMLQAKNLKVIGR 70
Query: 296 AGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD- 472
G GVD++DV +A + G+ V+ APG+N S E LM A+ +V + ++ G +
Sbjct: 71 PGVGVDDVDVKTATELGIPVVIAPGSNTRSVAEHAFALMFACAKDIVRSDNEMRKGNFAI 130
Query: 473 RALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFV---SADQCAQFHCTKM 643
R+ Y EL KTLA++G GR+G +A A GMN+ +DPFV + +Q +CT
Sbjct: 131 RSSYKAYELNHKTLALIGYGRIGSILAQMSKAIGMNVKVYDPFVKQGTIEQEGYIYCT-- 188
Query: 644 ELEDIWPLADYITLHTPLIXSTRNFI 721
EL+D+ + I++H PL TRN I
Sbjct: 189 ELDDVIRDSHVISIHVPLTNETRNLI 214
>UniRef50_Q3CIY1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding; n=2;
Thermoanaerobacter ethanolicus|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, catalytic region:D- isomer
specific 2-hydroxyacid dehydrogenase, NAD-binding -
Thermoanaerobacter ethanolicus ATCC 33223
Length = 319
Score = 115 bits (276), Expect = 1e-24
Identities = 71/203 (34%), Positives = 115/203 (56%), Gaps = 1/203 (0%)
Frame = +2
Query: 125 CAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGA 304
C +LN +G T EE++ + DAL+V + +V +V+ +LK++ + G
Sbjct: 29 CEVVLNPFGRPFTN------EEIIRYASDADALIVGN-DKVPGDVIKKCKRLKIIAKHGV 81
Query: 305 GVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALY 484
GVD+IDV +A + G+ V NAPG N+ +L L+ +LAR + A+T K G+W + +
Sbjct: 82 GVDSIDVKTANQLGIVVTNAPGTNSEEVADLAFGLLHMLARGLYQANTDTKNGKWIKPV- 140
Query: 485 TGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTK-MELEDIW 661
G L+ KT+ I+G+G +G VA R + MNI+G+D + + A K + L+++
Sbjct: 141 -GISLSKKTIGIIGVGTIGTAVAKRATGYDMNILGYD--IKKNPLALGLGVKYVGLDELL 197
Query: 662 PLADYITLHTPLIXSTRNFINAD 730
AD+I+LH PL T N +NAD
Sbjct: 198 SEADFISLHLPLTNDTLNILNAD 220
>UniRef50_Q214B1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding precursor; n=2;
Proteobacteria|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding precursor - Rhodopseudomonas
palustris (strain BisB18)
Length = 336
Score = 115 bits (276), Expect = 1e-24
Identities = 70/215 (32%), Positives = 114/215 (53%), Gaps = 2/215 (0%)
Frame = +2
Query: 89 KSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDA 268
K +L+ + + E L + G T + + ++ ++ +IP D ++VR + ++ V DA
Sbjct: 23 KRILLPQELMPEGREYLESRGYQLVTGSGMDEDHVIHDIPECDGIIVR-LSPMSARVFDA 81
Query: 269 GVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPAST 448
KLKV+ R G+G D +D+ +A K GV V+NAP AN+ S EL ML +R+
Sbjct: 82 AKKLKVLVRHGSGYDTVDLAAAKKHGVTVLNAPLANSTSVAELALFYMLHCSRNFRLVQQ 141
Query: 449 ALKAGRWDRALYT-GSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPF-VSADQCA 622
+ + L T SE+A K L ++G+G +G VA F M +IGFDP+ AD
Sbjct: 142 TMLVDYYKAKLDTPKSEIACKKLGLIGVGNIGSRVAKMARGFDMQVIGFDPYKTQADMPE 201
Query: 623 QFHCTKMELEDIWPLADYITLHTPLIXSTRNFINA 727
T+ + + I+ D+++LH P T+ F+NA
Sbjct: 202 GVELTQ-DFDRIFTDCDFVSLHCPSTPETKGFVNA 235
>UniRef50_Q6L245 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Thermoplasmatales|Rep: D-3-phosphoglycerate
dehydrogenase - Picrophilus torridus
Length = 299
Score = 114 bits (275), Expect = 2e-24
Identities = 65/201 (32%), Positives = 111/201 (55%)
Frame = +2
Query: 95 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 274
+LI D V E L+ I+++ELL +I ++D ++VRS T++ ++++D
Sbjct: 5 ILICDPVDGIMIEKLSK-DFDIDNSPDITRDELLKKIGDYDIIIVRSRTKIDRDIIDNAK 63
Query: 275 KLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL 454
+LK++ RAG G D+IDVD A +KG+ ++ APG++ S ELT ++ AR ++
Sbjct: 64 RLKIIARAGIGTDSIDVDYAQEKGIKIVYAPGSSTESVVELTVAFAVIAARQIIKGVENT 123
Query: 455 KAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHC 634
+ D G EL+GKTL I+G GR+GR +A F + I +D + A+
Sbjct: 124 RKN--DFTKLKGIELSGKTLGIIGYGRIGRAIANAFSVFNVRSIAYDAYPVDFTGAE--- 178
Query: 635 TKMELEDIWPLADYITLHTPL 697
++ LED+ +D I+++ L
Sbjct: 179 -QVTLEDLLRNSDIISINITL 198
>UniRef50_Q88ZU6 Cluster: Phosphoglycerate dehydrogenase; n=2;
Lactobacillus|Rep: Phosphoglycerate dehydrogenase -
Lactobacillus plantarum
Length = 392
Score = 114 bits (274), Expect = 2e-24
Identities = 71/184 (38%), Positives = 102/184 (55%), Gaps = 12/184 (6%)
Frame = +2
Query: 215 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 394
DA ++RS T E L + LKV+ RAGAGV+NI +D A G V N PG+NA + E
Sbjct: 31 DAYLIRSVNLHT-ETLPSS--LKVIVRAGAGVNNIPIDQATANGTAVFNTPGSNANAVKE 87
Query: 395 LTCTLMLVLARHVVPAST---------ALKAGRWDRALYTGSELAGKTLAILGLGRVGRE 547
L L+++ +R+++ A+T + D+ + G EL GKTLA++GLG VG
Sbjct: 88 LIIGLLIMASRNLIAATTYSAQHTEADISQRTEHDKTQFNGIELTGKTLAVIGLGHVGAL 147
Query: 548 VATRMYAFGMNIIGFDPFVSAD---QCAQFHCTKMELEDIWPLADYITLHTPLIXSTRNF 718
VA + GMN+IG+DP++SAD A+ L D AD++T+H P T +
Sbjct: 148 VANAALSLGMNVIGYDPYLSADAAWNIAKQVQRAATLPDAVKQADFVTVHVPKNADTLHL 207
Query: 719 INAD 730
IN D
Sbjct: 208 INKD 211
>UniRef50_Q49ZM5 Cluster: Putative dehydrogenase; n=1;
Staphylococcus saprophyticus subsp. saprophyticus ATCC
15305|Rep: Putative dehydrogenase - Staphylococcus
saprophyticus subsp. saprophyticus (strain ATCC 15305
/DSM 20229)
Length = 318
Score = 114 bits (274), Expect = 2e-24
Identities = 61/174 (35%), Positives = 95/174 (54%), Gaps = 3/174 (1%)
Frame = +2
Query: 176 ISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGV 355
I KE L + + DAL+ +T V KEV+DA LK++ GAG +N+D+D A ++ + V
Sbjct: 34 IDKETLKQGVKDADALISLLSTSVDKEVIDAANNLKIITNYGAGFNNVDIDYARQQNIDV 93
Query: 356 INAPGANALSACELTCTLMLVLARHVVPASTALKA---GRWDRALYTGSELAGKTLAILG 526
N P A+ S ELT L+L +AR + + W + G E++GKT+ I+G
Sbjct: 94 TNTPKASTNSTAELTFALVLAVARRIPEGDKLCRTTGFDGWAPLFFRGREVSGKTIGIIG 153
Query: 527 LGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYITLH 688
LG +G VA R AF MNI+ P D+ + ++LE + AD++T++
Sbjct: 154 LGEIGSAVARRAKAFDMNILYTGPHQKVDKEREIGAKYVDLETLLKNADFVTIN 207
>UniRef50_Q88YI0 Cluster: Phosphoglycerate dehydrogenase; n=5;
Bacilli|Rep: Phosphoglycerate dehydrogenase -
Lactobacillus plantarum
Length = 324
Score = 113 bits (273), Expect = 3e-24
Identities = 63/187 (33%), Positives = 102/187 (54%), Gaps = 4/187 (2%)
Frame = +2
Query: 176 ISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGV 355
IS EL+ + + D L++ +TQV ++VLD LK++ GAG +NID+ +A K+ + V
Sbjct: 34 ISHAELIRRVADADFLIIPLSTQVDQDVLDHAPHLKLIANFGAGTNNIDIAAAAKRQIPV 93
Query: 356 INAPGANALSACELTCTLMLVLARHVVPASTALKA---GRWDRALYTGSELAGKTLAILG 526
N P +A++ E T L++ LA +V ++ W + G L GKTL ILG
Sbjct: 94 TNTPNVSAVATAESTVGLIISLAHRIVEGDHLMRTSGFNGWAPLFFLGHNLQGKTLGILG 153
Query: 527 LGRVGREVATRMYAFGMNIIGFDPF-VSADQCAQFHCTKMELEDIWPLADYITLHTPLIX 703
LG++G+ VA R++AF M I+ + + Q T + +++ AD +TLH PL
Sbjct: 154 LGQIGQAVAKRLHAFDMPILYSQHHRLPISRETQLGATFVSQDELLQRADIVTLHLPLTT 213
Query: 704 STRNFIN 724
T + I+
Sbjct: 214 QTTHLID 220
>UniRef50_Q7D366 Cluster: AGR_pAT_578p; n=2; Agrobacterium
tumefaciens str. C58|Rep: AGR_pAT_578p - Agrobacterium
tumefaciens (strain C58 / ATCC 33970)
Length = 317
Score = 113 bits (273), Expect = 3e-24
Identities = 57/181 (31%), Positives = 97/181 (53%)
Frame = +2
Query: 185 EELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINA 364
+EL + + DA++ T + V + +LK + R G GVDNID+D+A + G+ V NA
Sbjct: 42 DELSARLGDVDAVIAGVDTW-NERVFNLAPRLKAIARFGVGVDNIDIDAAHRHGIAVTNA 100
Query: 365 PGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGR 544
PG NA + ELT L+L R + AL+ G WDR + G EL G+ + +LG G + R
Sbjct: 101 PGGNANAVAELTLGLILSAMRRIPYLHDALRGGAWDR--FVGQELIGRRVGLLGFGNIAR 158
Query: 545 EVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYITLHTPLIXSTRNFIN 724
++A ++ F + +I +D F + E++++ +D + + P + TR ++
Sbjct: 159 KIARKLCGFDVEVIAYDKFPDQVAATKLGVRMCEMDEVLSSSDILVMMMPSLPETRRLMD 218
Query: 725 A 727
A
Sbjct: 219 A 219
>UniRef50_A6C853 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Planctomyces maris DSM 8797|Rep: D-3-phosphoglycerate
dehydrogenase - Planctomyces maris DSM 8797
Length = 328
Score = 113 bits (273), Expect = 3e-24
Identities = 69/206 (33%), Positives = 113/206 (54%), Gaps = 6/206 (2%)
Frame = +2
Query: 131 ELLNAYGI---ATTTKAKISKE--ELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGR 295
E+L A G T+ + KE ++ ++ +DA V+ A ++EVL LKV+ R
Sbjct: 18 EILQAAGFEVDTVPTEVDLRKEPHRVVEQVQGYDA-VLAGAEIYSREVLQQLPDLKVISR 76
Query: 296 AGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDR 475
G G D +D+ +A + + V PG N S E L++ +AR A+++G W+R
Sbjct: 77 YGVGFDAVDLAAADAQNIVVTITPGVNHHSVAEQAFALLMGIARMTRTQDRAVRSGEWER 136
Query: 476 ALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTK-MELE 652
L + G T+ I+GLGR+G+ VATR GM+++ +DPF + ++ A+ H K + LE
Sbjct: 137 ELTP--RVWGSTIGIVGLGRIGQAVATRAIGMGMHVLAYDPFPN-EEFAKTHQIKLLSLE 193
Query: 653 DIWPLADYITLHTPLIXSTRNFINAD 730
++ +DY+TLH P+ T + IN D
Sbjct: 194 ELLKQSDYVTLHLPVTPETIDIINRD 219
>UniRef50_Q031D4 Cluster: Phosphoglycerate dehydrogenase; n=20;
Streptococcaceae|Rep: Phosphoglycerate dehydrogenase -
Lactococcus lactis subsp. cremoris (strain SK11)
Length = 398
Score = 113 bits (271), Expect = 6e-24
Identities = 60/164 (36%), Positives = 97/164 (59%), Gaps = 14/164 (8%)
Frame = +2
Query: 275 KLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL 454
+L +GRAGAG +NI ++ KG+ V NAPG NA + EL ++M+ R++ PA+ L
Sbjct: 52 ELLAIGRAGAGFNNIPIEKCASKGIVVFNAPGGNANAVKELVLSMMIFGTRNLKPANKWL 111
Query: 455 KAGRW-DRAL----------YTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPF 601
+ D+A+ ++GSE++GKTL ++GLG +G +VA GM +IG+DP+
Sbjct: 112 TGQKGNDKAIDVAVENGKKAFSGSEISGKTLGVIGLGNIGSKVANDAQRLGMKVIGYDPY 171
Query: 602 VSADQC--AQFHCTKM-ELEDIWPLADYITLHTPLIXSTRNFIN 724
+S + H ++ +L +I+ ADYIT+HTP T+ +N
Sbjct: 172 LSIEHAWNLSHHVKRVNDLSEIFEKADYITVHTPATDETKGMLN 215
>UniRef50_A0VQR0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Dinoroseobacter shibae
DFL 12|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Dinoroseobacter shibae DFL
12
Length = 316
Score = 113 bits (271), Expect = 6e-24
Identities = 61/179 (34%), Positives = 93/179 (51%), Gaps = 1/179 (0%)
Frame = +2
Query: 194 LMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGA 373
L+ + D ++VR+ TQV + LDA +L+V+G G G+DNID+ + +G+ V A GA
Sbjct: 39 LVAVARADGVIVRNRTQVDRPFLDAASRLRVIGLLGTGLDNIDMAACAARGISVHPATGA 98
Query: 374 NALSACELTCTLMLVLARHVVPASTALKAGRWDRA-LYTGSELAGKTLAILGLGRVGREV 550
N S E T L+L R ++ ++ G W R L G E+AG+ L + G G V + V
Sbjct: 99 NTRSVAEYVITAALMLTRRAFMSTPEMQEGAWPRGPLGEGGEIAGRKLGLYGCGAVAQAV 158
Query: 551 ATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYITLHTPLIXSTRNFINA 727
A M I+G DP + T++ ++ AD ++LH PL TR I+A
Sbjct: 159 ARLAKPLSMTILGHDPHLGPGHPLWTEVTRVSDAELLARADVLSLHLPLTPETRGRIDA 217
>UniRef50_A1G3C5 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Salinispora arenicola
CNS205|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Salinispora arenicola
CNS205
Length = 345
Score = 112 bits (269), Expect = 1e-23
Identities = 65/173 (37%), Positives = 94/173 (54%), Gaps = 3/173 (1%)
Frame = +2
Query: 221 LVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELT 400
L VR Q+T +VLDA +L V +G GVDNID+ +A + GV V N PG E
Sbjct: 47 LAVRYPAQITADVLDAAPQLLAVLSSGRGVDNIDIPAASRAGVVVANNPGLGGKPVSEHA 106
Query: 401 CTLMLVLARHVVPASTALKAGRWDRALYTGS-ELAGKTLAILGLGRVGREVATRMYA-FG 574
L++++ R + + G W++ L T EL G TL I+G G VG +A R A F
Sbjct: 107 LGLLIMITRDLTAVARDAMTGAWEKRLTTRRVELTGGTLGIVGCGNVGGWMARRASAGFQ 166
Query: 575 MNIIGFDPFVSADQCAQFHCTKME-LEDIWPLADYITLHTPLIXSTRNFINAD 730
M ++ +DP+VSA+Q AQ TK++ L+ + AD+++ H L T N D
Sbjct: 167 MRVLAYDPYVSAEQMAQVGATKVDNLDKLLAEADFVSCHPELNDETDGMFNDD 219
>UniRef50_Q83AZ4 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=11; Bacteria|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase family
protein - Coxiella burnetii
Length = 388
Score = 111 bits (268), Expect = 1e-23
Identities = 71/197 (36%), Positives = 105/197 (53%), Gaps = 14/197 (7%)
Frame = +2
Query: 182 KEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVIN 361
K LL E DA++VRS K++ D +++V+GRAG GV+NI V GV V+N
Sbjct: 23 KYTLLTECEEPDAILVRSCNLHDKKIAD---RVQVIGRAGVGVNNIPVRPLTLSGVPVLN 79
Query: 362 APGANALSACELTCTLMLVLARHVVPA-----------STALKAGRWDRALYTGSELAGK 508
PGANA + EL T +L+ +RH+ PA T ++ ++G EL GK
Sbjct: 80 TPGANANAVKELVITGILLASRHIYPALDYARHIEGDDETITHQVEKNKKRFSGFELPGK 139
Query: 509 TLAILGLGRVGREVATRMYAFGMNIIGFDPFV---SADQCAQFHCTKMELEDIWPLADYI 679
TL I+GLG++G +VA GM IG+DP + SA + + L D+ +D++
Sbjct: 140 TLGIIGLGQIGVKVANAAIRLGMKAIGYDPAITVRSAWELSSEVAQAESLRDVLRNSDFV 199
Query: 680 TLHTPLIXSTRNFINAD 730
T+H PL T + IN +
Sbjct: 200 TVHVPLNTHTHHLINEE 216
>UniRef50_Q6A5K9 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, putative D-3- phosphoglycerate
dehydrogenase; n=1; Propionibacterium acnes|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase, putative
D-3- phosphoglycerate dehydrogenase - Propionibacterium
acnes
Length = 321
Score = 111 bits (268), Expect = 1e-23
Identities = 64/194 (32%), Positives = 109/194 (56%), Gaps = 9/194 (4%)
Frame = +2
Query: 176 ISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGV 355
+ ++EL +I DA++ + + E++ G LKV+G+ AG +NID+D+A + GV V
Sbjct: 31 MDRQELSRQIATADAILTSLSDPLDAEMIGQGKNLKVIGQCAAGFNNIDLDAAKQAGVVV 90
Query: 356 INAPGANALSACELTCTLMLVLARHVVPASTALKAG---RWDRALYTGSELAGKTLAILG 526
+ PG + +L TL+L + R A ++AG R+D G+ L G TL I+G
Sbjct: 91 TSTPGVLHEATADLAFTLLLEVTRRTGEAERWVRAGRAWRYDHTFMLGAGLQGATLGIVG 150
Query: 527 LGRVGREVATRMYAFGMNII---GFDPFVSADQCAQFH---CTKMELEDIWPLADYITLH 688
LG++G +A R AFGMN+I + V+A + ++EL++++ +D ++LH
Sbjct: 151 LGQIGEAMARRGAAFGMNVIYNARHEKDVAAIDAVNLNTQPTRRVELDELFATSDVVSLH 210
Query: 689 TPLIXSTRNFINAD 730
PL TR+ ++AD
Sbjct: 211 CPLTDETRHLVDAD 224
>UniRef50_Q0FX01 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD binding subunit; n=3;
Rhodobacteraceae|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD binding subunit - Roseovarius sp.
HTCC2601
Length = 326
Score = 111 bits (268), Expect = 1e-23
Identities = 61/158 (38%), Positives = 89/158 (56%)
Frame = +2
Query: 215 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 394
DALVV VT E L G KL+ V + G GVDNID+ + + G+ V N P ANA + E
Sbjct: 53 DALVV-GLVPVTPETLTQGGKLRAVIKHGVGVDNIDIPACTEAGLPVCNTPAANADAVAE 111
Query: 395 LTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFG 574
L LM +AR + ++ AG WDR + G++L GKTL I+GLG +G+ +A G
Sbjct: 112 LAVGLMFSMARWIPQGHASVTAGGWDRRI--GTQLGGKTLGIVGLGNIGKRLAKLARGLG 169
Query: 575 MNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYITLH 688
M ++ D + A+ + + LE++ +DYI+LH
Sbjct: 170 MQVVATDKYPDEAFAAEHGISFLPLEELLAQSDYISLH 207
>UniRef50_A7NGZ0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=1; Roseiflexus castenholzii
DSM 13941|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding - Roseiflexus castenholzii DSM
13941
Length = 345
Score = 111 bits (268), Expect = 1e-23
Identities = 63/178 (35%), Positives = 92/178 (51%), Gaps = 3/178 (1%)
Frame = +2
Query: 203 IPNHDALVVRSATQVTKEVLD-AGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANA 379
+P A ++ + +D AG L + R G GVDNID+ +A ++G+ VIN P
Sbjct: 44 LPGSAAAIISAMINADGAWMDRAGPTLMAIARPGIGVDNIDLAAATERGILVINTPDGPT 103
Query: 380 LSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVA-T 556
S E L+L LA+ VV A + W A G E+ GKTL ++GLGR+GR VA
Sbjct: 104 ESTAEHAVALVLALAKQVVAADHRFRTAGWSAARLRGVEVRGKTLGVVGLGRIGRRVAQI 163
Query: 557 RMYAFGMNIIGFDPFVSADQCAQFHCTKME-LEDIWPLADYITLHTPLIXSTRNFINA 727
GM + +DP A+ A +E L+++ P ++++TLH L STR I A
Sbjct: 164 CRQGLGMRVAAYDPLAPAEAFAALDVVHVETLDNLLPQSEFLTLHCALTPSTRGLIGA 221
>UniRef50_Q3KBX8 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=2; Pseudomonas|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Pseudomonas fluorescens (strain PfO-1)
Length = 324
Score = 111 bits (267), Expect = 2e-23
Identities = 67/178 (37%), Positives = 96/178 (53%), Gaps = 3/178 (1%)
Frame = +2
Query: 200 EIPNH-DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGAN 376
EI N DA+ +R ++ E++ A KL++V R GAG DN+D +A + GV V N PGAN
Sbjct: 37 EIQNEVDAVFLRGG-HISAEMIAASPKLRIVARHGAGYDNVDYKAAAELGVWVTNTPGAN 95
Query: 377 ALSACELTCTLMLVLARHVVPASTALKAGRW--DRALYTGSELAGKTLAILGLGRVGREV 550
S E L+L ++R V A+ + W DR TG EL G+TL ++G G +GR V
Sbjct: 96 RRSVVEHVFALLLGISRKVQLATDQTRNNIWAQDRLSLTGIELEGRTLGLIGFGDIGRHV 155
Query: 551 ATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYITLHTPLIXSTRNFIN 724
A AFGM ++ DP F ++L+ + AD ++LH PL T N I+
Sbjct: 156 APVAEAFGMKVLATDPAYD----TSFDKRLVDLDTLLTQADVVSLHVPLQEGTENLIS 209
>UniRef50_Q8Y3L1 Cluster: Lmo2824 protein; n=14; Bacillales|Rep:
Lmo2824 protein - Listeria monocytogenes
Length = 395
Score = 111 bits (266), Expect = 2e-23
Identities = 62/164 (37%), Positives = 91/164 (55%), Gaps = 13/164 (7%)
Frame = +2
Query: 278 LKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALK 457
+K V RAGAGV+NI V++ +KG+ V N PGANA + EL + V AR ++ + +K
Sbjct: 50 VKAVARAGAGVNNIPVENCSEKGIVVFNTPGANANAVKELVLASLFVSARPILEGTEWVK 109
Query: 458 AGRWD----------RALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVS 607
+ + + G+ELAGK L I+GLG +G VA + GM+++G+DPFVS
Sbjct: 110 ELPAEDDVEQKVEAGKKAFAGTELAGKKLGIIGLGAIGALVANDALSLGMDVVGYDPFVS 169
Query: 608 ADQCAQFHC---TKMELEDIWPLADYITLHTPLIXSTRNFINAD 730
D + M +E++ DY+T+H PL TR NAD
Sbjct: 170 VDTAWRISKEVERAMTIEEVLATCDYLTVHVPLTDKTRGMFNAD 213
>UniRef50_O58320 Cluster: Glyoxylate reductase; n=16; cellular
organisms|Rep: Glyoxylate reductase - Pyrococcus
horikoshii
Length = 334
Score = 111 bits (266), Expect = 2e-23
Identities = 60/193 (31%), Positives = 100/193 (51%), Gaps = 7/193 (3%)
Frame = +2
Query: 173 KISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVG 352
+I +E LL ++ DALV + ++ KEV + KL++V G DNID++ A K+G+
Sbjct: 33 EIPREILLKKVKEVDALVTMLSERIDKEVFENAPKLRIVANYAVGYDNIDIEEATKRGIY 92
Query: 353 VINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDR-------ALYTGSELAGKT 511
V N P + +L L+L ARHVV +++G W + + G ++ GKT
Sbjct: 93 VTNTPDVLTDATADLAFALLLATARHVVKGDRFVRSGEWKKRGVAWHPKWFLGYDVYGKT 152
Query: 512 LAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYITLHT 691
+ I+GLGR+G+ +A R F M I+ + + + + LED+ +D++ L
Sbjct: 153 IGIIGLGRIGQAIAKRAKGFNMRILYYSRTRKEEVERELNAEFKPLEDLLRESDFVVLAV 212
Query: 692 PLIXSTRNFINAD 730
PL T + IN +
Sbjct: 213 PLTRETYHLINEE 225
>UniRef50_A6ULR7 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=1; Sinorhizobium medicae
WSM419|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding - Sinorhizobium medicae WSM419
Length = 328
Score = 110 bits (265), Expect = 3e-23
Identities = 65/188 (34%), Positives = 104/188 (55%)
Frame = +2
Query: 164 TKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKK 343
T+A+++ E L P DA++ R+ + +++ L+V+ R G G +N+D++SA ++
Sbjct: 34 TEAELA--ESLRSTP-FDAVISRTLA-LPAMMIETAPALRVISRHGVGYNNVDIESATRR 89
Query: 344 GVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAIL 523
GV V+ A GAN S EL L L +AR + +++A +W+R+ Y G + AGKT I+
Sbjct: 90 GVPVLIADGANGKSVAELAVGLALSVARKITTQDASIRARQWNRSAY-GLQFAGKTAGIV 148
Query: 524 GLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYITLHTPLIX 703
G +GR VA + A M II FDP T+ L+++ +D ++LH PL
Sbjct: 149 AFGAIGRRVAEILRAMDMRIIAFDPHARDRSTTGVDWTE-TLDELLQESDLVSLHCPLTP 207
Query: 704 STRNFINA 727
TRN I A
Sbjct: 208 ETRNMITA 215
>UniRef50_A5N5A9 Cluster: SerA; n=1; Clostridium kluyveri DSM
555|Rep: SerA - Clostridium kluyveri DSM 555
Length = 320
Score = 110 bits (265), Expect = 3e-23
Identities = 63/211 (29%), Positives = 114/211 (54%), Gaps = 2/211 (0%)
Frame = +2
Query: 95 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 274
+LI + + + E L +G S++ L+ E+ + DA++VR A +T++V+ AG
Sbjct: 5 ILITESIEEEGVEYLKKFGYEIKMPRDTSEDVLIEEVKDCDAILVRMAN-ITEKVIRAGK 63
Query: 275 KLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL 454
KLKV+ R G GV+N+D+ +A + + + NAP +N + E T L++ LA+ L
Sbjct: 64 KLKVISRFGVGVNNVDIKTASELSIQITNAPESNKNTVAEYTMGLIIALAKKFFLYDRGL 123
Query: 455 KAGRWDRALYTGSELAGKTLAILGLGRVGREVATR-MYAFGMNIIGFDPFVSADQCAQFH 631
+ G + G +L GK L I+GLG +G+ +A + FGM +IGF + + + +
Sbjct: 124 RKGNFKVRDILGIDLEGKVLGIVGLGSIGKLLALKASKGFGMKVIGFKRHIDEESKSLDY 183
Query: 632 CTKME-LEDIWPLADYITLHTPLIXSTRNFI 721
+ L+ + +D+++L+ PL +T I
Sbjct: 184 VELTDSLDYVLENSDFVSLNVPLTKATTKII 214
>UniRef50_Q5KYJ7 Cluster: Dehydrogenase; n=3; Firmicutes|Rep:
Dehydrogenase - Geobacillus kaustophilus
Length = 334
Score = 110 bits (264), Expect = 4e-23
Identities = 60/202 (29%), Positives = 113/202 (55%), Gaps = 4/202 (1%)
Frame = +2
Query: 131 ELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGV 310
E+L++ + ++EE++ + DA++ + A ++ EV+ K K++ R G GV
Sbjct: 21 EVLSSLNVEFVATQCRTEEEVISACRDADAIINQYAP-ISAEVIAQLEKCKIISRYGVGV 79
Query: 311 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD----RA 478
+ +DVD+A +KG+ V N + + L+L LAR +V + +K+G W+ +
Sbjct: 80 NTVDVDAATEKGIIVANVTDYSIDEVSDHALALLLSLARKIVKLNHEVKSGTWNFNVGKP 139
Query: 479 LYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDI 658
+Y L G+TL ++GLGR+ + +A + AFG+ +I +DP+V A + + + L D+
Sbjct: 140 IY---RLRGRTLGLVGLGRIPQALAKKAQAFGLRVIAYDPYVPAKVADELNVQLLGLNDV 196
Query: 659 WPLADYITLHTPLIXSTRNFIN 724
+ +DYI++H PL T+ I+
Sbjct: 197 FRQSDYISVHAPLTKETKGMIS 218
>UniRef50_A5URV2 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Roseiflexus sp.
RS-1|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Roseiflexus sp. RS-1
Length = 323
Score = 109 bits (263), Expect = 5e-23
Identities = 61/156 (39%), Positives = 86/156 (55%), Gaps = 2/156 (1%)
Frame = +2
Query: 266 AGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPAS 445
AG L+ + R G GVDNID+ +A K+G+ VIN P S E L+L LA+ VV +
Sbjct: 65 AGDALRAICRPGIGVDNIDIAAATKRGILVINTPDGPTESTAEHAVALLLALAKQVVASD 124
Query: 446 TALKAGRWDRALYTGSELAGKTLAILGLGRVGREVA-TRMYAFGMNIIGFDPFVSADQCA 622
L+ W A G E+ GKTL I+GLGR+GR VA GM+++ +DP V + A
Sbjct: 125 RVLRTEGWRAARLRGIEVRGKTLGIVGLGRIGRRVAQICRQGLGMHVVAYDPPVPDETFA 184
Query: 623 QFHCTK-MELEDIWPLADYITLHTPLIXSTRNFINA 727
+ L+D+ P A +++LH L TR+ I A
Sbjct: 185 TLDVARAATLDDLLPHAQFLSLHCALTPETRHLIGA 220
>UniRef50_Q9TXJ5 Cluster: D-3-phosphoglycerate dehydrogenase-like
protein; n=10; cellular organisms|Rep:
D-3-phosphoglycerate dehydrogenase-like protein -
Leishmania major
Length = 511
Score = 109 bits (263), Expect = 5e-23
Identities = 66/214 (30%), Positives = 110/214 (51%), Gaps = 3/214 (1%)
Frame = +2
Query: 98 LIVDGVGAKCAELLNAYG-IATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 274
L+++GV ELL + G I + ++ LL +I + L +RS TQVT+ +LDA
Sbjct: 116 LLLEGVNPIAKELLESKGCIVEYIPNALPRDTLLEKIRDVHFLGIRSKTQVTQAILDAAP 175
Query: 275 KLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL 454
KL +G G + +D+D A +GV V N+P AN S EL ++ L+R + S +
Sbjct: 176 KLLGIGCFCIGTNQVDLDYATTRGVAVFNSPFANTRSVAELVIGEIISLSRKMTQRSEEV 235
Query: 455 KAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFD--PFVSADQCAQF 628
G W++ E+ GKT+ I+G G +G +V A GMN++ +D P ++ +F
Sbjct: 236 HRGVWNKTHVGCYEVRGKTVGIVGYGHIGSQVGVLAEALGMNVVFYDVLPTLAIGNATKF 295
Query: 629 HCTKMELEDIWPLADYITLHTPLIXSTRNFINAD 730
+ D+ +D++T+H P T+ I +
Sbjct: 296 ----THINDLLTFSDFVTIHVPETDVTKGMIGEE 325
>UniRef50_A4ARG6 Cluster: D-3-phosphoglycerate dehydrogenase; n=14;
Bacteroidetes|Rep: D-3-phosphoglycerate dehydrogenase -
Flavobacteriales bacterium HTCC2170
Length = 329
Score = 109 bits (261), Expect = 9e-23
Identities = 79/223 (35%), Positives = 112/223 (50%), Gaps = 18/223 (8%)
Frame = +2
Query: 80 VDIKSVLIVDGVGAKCAELLNAYG--IATTTKAKISKEELLMEIPNHDA-LVVRSATQVT 250
V+ +L DG+ L A G I+TTT A+ +E + E N A L+VRSATQV
Sbjct: 11 VNSMKILANDGISQTGINELEAAGFEISTTTVAQEQLKEFINE--NQIAGLLVRSATQVR 68
Query: 251 KEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLM------ 412
K+++D LK++GR G G+DNIDV A +KG+ VIN P A++ S EL +
Sbjct: 69 KDIIDNCPSLKLIGRGGVGMDNIDVAYAKEKGLHVINTPAASSESVAELVFAHLFGGVRF 128
Query: 413 LVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGF 592
L A +P K + ++ GSEL GKTL ++G GR+G+ A GM +I
Sbjct: 129 LYDANRNMPLEGDSKFKQLKKSYAGGSELRGKTLGVIGFGRIGQATAKIALGIGMKVIYS 188
Query: 593 DPFVSA---------DQCAQFHCTKMELEDIWPLADYITLHTP 694
DPF+ Q F ++ AD+I+LH P
Sbjct: 189 DPFIEKASIELPFFDGQKVSFDFVSKSKSELLQNADFISLHVP 231
>UniRef50_Q7WM64 Cluster: Putative dehydrogenase; n=2;
Bordetella|Rep: Putative dehydrogenase - Bordetella
bronchiseptica (Alcaligenes bronchisepticus)
Length = 330
Score = 108 bits (260), Expect = 1e-22
Identities = 64/202 (31%), Positives = 106/202 (52%), Gaps = 3/202 (1%)
Frame = +2
Query: 98 LIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVK 277
LIV + + LL G+ A + ++ I + DA + R+A T+ + +AG +
Sbjct: 9 LIVQPIHEEGLALLREAGVECIAPASAAMADVAAAIADCDAAITRNAGLDTRAI-EAGRR 67
Query: 278 LKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALK 457
L+V+G G G + ID+ +A + G+ V+N PGANA S EL + + L + VP A++
Sbjct: 68 LRVIGNHGTGTNMIDLAAAERLGIPVVNTPGANARSVAELALAMAMALLKRTVPLDQAVR 127
Query: 458 AGRWDRALYTG-SELAGKTLAILGLGRVGREVAT-RMYAFGMNIIGFDPFVSADQCAQFH 631
G W+ G EL+G +L I+G G++GR +A + FGM + + P V+ A
Sbjct: 128 QGNWNIRYEAGLRELSGMSLGIVGFGQIGRALAAMAIGGFGMRVHVYSPSVAPQDIAAAG 187
Query: 632 CTKME-LEDIWPLADYITLHTP 694
C + + L + AD ++LH P
Sbjct: 188 CQRADSLPALAREADIVSLHRP 209
>UniRef50_A1HM37 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=3; cellular organisms|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Thermosinus carboxydivorans Nor1
Length = 365
Score = 108 bits (260), Expect = 1e-22
Identities = 59/187 (31%), Positives = 103/187 (55%), Gaps = 4/187 (2%)
Frame = +2
Query: 173 KISKEELLMEIPNHDA-LVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGV 349
+I + + L++ DA L+ ++ +V DA KL++VG + AG++N++V A K+G+
Sbjct: 60 EIEEVDALIQSEGKDAELLAGLFVPISSKVFDAMPKLRIVGVSRAGLENVNVKEATKRGI 119
Query: 350 GVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGS---ELAGKTLAI 520
V N G NA + + T LML R++ A ++K G W + EL GK + +
Sbjct: 120 LVFNIEGRNAEAVSDFTVGLMLAECRNIARAHYSIKNGGWRKEFSNSDWVPELKGKKVGL 179
Query: 521 LGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYITLHTPLI 700
+G G +GR VA ++ FG+ + +DPFV + C ++ E ++ +D+I+LH L
Sbjct: 180 VGFGYIGRLVAQKLSGFGVTRLVYDPFVDEETIRGAGCIPVDKETLFKESDFISLHARLS 239
Query: 701 XSTRNFI 721
ST+N +
Sbjct: 240 ESTKNLV 246
>UniRef50_A1HMI9 Cluster: Phosphoglycerate dehydrogenase; n=1;
Thermosinus carboxydivorans Nor1|Rep: Phosphoglycerate
dehydrogenase - Thermosinus carboxydivorans Nor1
Length = 326
Score = 108 bits (259), Expect = 2e-22
Identities = 65/201 (32%), Positives = 106/201 (52%), Gaps = 3/201 (1%)
Frame = +2
Query: 131 ELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGV 310
E + G+ T ++ +E + + D +V + ++T+E++ KLK++ + G GV
Sbjct: 19 ESIKPSGVTVTYWYTLNDKEKEQALNSADYFLV-ALYKITQELIQKAPKLKMIQKTGVGV 77
Query: 311 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG 490
DNID+ +A G+ V N PG NA S ELT +++ L R + K G W +
Sbjct: 78 DNIDLAAAKTLGIPVANTPGGNATSVAELTLGMIINLYRKINILDRETKKGNWMSWEFRP 137
Query: 491 S--ELAGKTLAILGLGRVGREVATRMYAFGMNIIGFD-PFVSADQCAQFHCTKMELEDIW 661
S E+ GKT I+G G +GREVA AFG N+I +D + + + + T EL ++
Sbjct: 138 SSYEVKGKTHGIIGFGNIGREVARLSQAFGTNVIYYDLRRLEPAEEKRLNVTYHELNELL 197
Query: 662 PLADYITLHTPLIXSTRNFIN 724
+D I++H PL T+N I+
Sbjct: 198 QKSDIISIHLPLTPDTKNLIS 218
>UniRef50_Q825H6 Cluster: Putative glycerate dehydrogenase; n=1;
Streptomyces avermitilis|Rep: Putative glycerate
dehydrogenase - Streptomyces avermitilis
Length = 325
Score = 107 bits (258), Expect = 2e-22
Identities = 75/213 (35%), Positives = 113/213 (53%), Gaps = 6/213 (2%)
Frame = +2
Query: 110 GVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVV 289
G GA A + T +A L E H +++ VT E + A +L+++
Sbjct: 19 GAGAALASVFPGQARVTVVEATDEDPAALREA--H--VIITGLGPVTAEHIAAAPELQLI 74
Query: 290 GRAGAGVDNIDVDSAGKKGVGVIN--APGANALSACELTCTLMLVLARHVVPASTALKAG 463
A G D +D+D+A +G+ V N + GA + E T LML LA+ +VPA TAL
Sbjct: 75 QCASHGFDYVDLDAARARGLPVCNIGSSGAEQQNVAEQTFALMLALAKQLVPAHTALVDA 134
Query: 464 RW--DRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNII-GFDPFVSADQCAQFHC 634
W R + +EL+GKTL I+GLG +G EVA R AF M I+ V A++ A+
Sbjct: 135 DWALPRLQRSITELSGKTLGIVGLGHIGEEVARRAVAFDMRIVYAGRERVGAEREARLGG 194
Query: 635 TK-MELEDIWPLADYITLHTPLIXSTRNFINAD 730
+ + L+++ ADY+TLH PL +TR+ ++AD
Sbjct: 195 ARHVGLDELLRTADYVTLHAPLTEATRHLLDAD 227
>UniRef50_A1ZGW5 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Microscilla marina ATCC 23134|Rep: D-3-phosphoglycerate
dehydrogenase - Microscilla marina ATCC 23134
Length = 322
Score = 107 bits (258), Expect = 2e-22
Identities = 75/221 (33%), Positives = 112/221 (50%), Gaps = 8/221 (3%)
Frame = +2
Query: 83 DIKSVLIVDGVGAKCAELLNAYGIATTTK-AKISKEELLMEIPNHD-ALVVRSATQVTKE 256
+I VL +DG L+ Y T+ + S E + I H +V A + +E
Sbjct: 3 EIPIVLKIDGATYFEMPQLDGYLAKHQTRLVEASLNEAISAINEHSPGAIVSGAAPIGRE 62
Query: 257 VLDAGVK--LKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARH 430
++DAG++ L+ + +AG G+DNID + A + + V N P + E LML LAR
Sbjct: 63 IMDAGLQKGLRGIVKAGTGLDNIDCEYARCQQILVENIPDYVHETVAEYAINLMLSLARK 122
Query: 431 VVPASTALKAGRW--DRALYTGSELAGKTLAILGLGRVGREVA-TRMYAFGMNIIGFDPF 601
P ++ W G+EL GKT+ ++G GR+ R VA + F M++I +DP+
Sbjct: 123 SWPVQQTMRQKGWFDITPASLGTELNGKTIGLVGFGRIARSVARIAHFGFQMSVIAYDPY 182
Query: 602 VSADQCAQFHCTKME-LEDIWPLADYITLHTPLIXSTRNFI 721
VSA++ K E LEDI P D ++LHT L TRN I
Sbjct: 183 VSAEEMELCAVQKAEQLEDILPHCDVVSLHTSLNNDTRNLI 223
>UniRef50_UPI0000DA2A77 Cluster: PREDICTED: similar to
D-3-phosphoglycerate dehydrogenase (3-PGDH); n=2; Rattus
norvegicus|Rep: PREDICTED: similar to
D-3-phosphoglycerate dehydrogenase (3-PGDH) - Rattus
norvegicus
Length = 155
Score = 107 bits (257), Expect = 3e-22
Identities = 62/158 (39%), Positives = 95/158 (60%)
Frame = +2
Query: 83 DIKSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVL 262
+I VLI D + C ++L G+ ++KEEL+ E+ + + L ++SAT+VT + +
Sbjct: 5 NICKVLISDSLDPCCQKILQDGGLQN-----LNKEELITELQDCEGLTIQSATKVTADAV 59
Query: 263 DAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPA 442
+A KL+VVG AG G+DN+D+++A +K + V+N N+LS ELTC + L A P
Sbjct: 60 NAAQKLQVVGSAGTGMDNVDLEAAMRKSILVMNTSNGNSLSPVELTCGMNLCQAD--FPG 117
Query: 443 STALKAGRWDRALYTGSELAGKTLAILGLGRVGREVAT 556
+ + + G+ L GKTL LGLGR+GREVAT
Sbjct: 118 NNFNERWQMGPEEVHGATLTGKTLGNLGLGRIGREVAT 155
>UniRef50_Q82XE1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase; n=5; Proteobacteria|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase - Nitrosomonas
europaea
Length = 403
Score = 106 bits (254), Expect = 6e-22
Identities = 62/189 (32%), Positives = 103/189 (54%), Gaps = 14/189 (7%)
Frame = +2
Query: 200 EIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANA 379
+I D ++VRS E+ ++ + +GRAGAG +NI V+ +G+ V N PGANA
Sbjct: 35 DITGPDVILVRSHNLHDMEIPESVI---AIGRAGAGTNNIPVNQMSARGIPVFNTPGANA 91
Query: 380 LSACELTCTLMLVLARHVVPASTALKAGRWD-----------RALYTGSELAGKTLAILG 526
+ EL ML+ +R+++PA ++ D + ++G EL G+TL ++G
Sbjct: 92 NAVRELVLAGMLMASRNLIPALRFVETLEGDDQSFNLQVEAGKKQFSGLELPGRTLGVIG 151
Query: 527 LGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKM---ELEDIWPLADYITLHTPL 697
LG++GR+VA GM ++G+DP ++ D ++ED+ + +I+LH PL
Sbjct: 152 LGKIGRQVADIAIKLGMKVLGYDPKITIDSAWSLPAEVQKANQIEDLIRRSQFISLHVPL 211
Query: 698 IXSTRNFIN 724
STR+ IN
Sbjct: 212 NDSTRHLIN 220
>UniRef50_A3ZW64 Cluster: Phosphoglycerate dehydrogenase, putative;
n=1; Blastopirellula marina DSM 3645|Rep:
Phosphoglycerate dehydrogenase, putative -
Blastopirellula marina DSM 3645
Length = 320
Score = 106 bits (254), Expect = 6e-22
Identities = 57/168 (33%), Positives = 90/168 (53%)
Frame = +2
Query: 224 VVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTC 403
V+ S T EVL +++VV R G G D+++V +A ++ + V PG S E T
Sbjct: 49 VICSTEPYTAEVLSR-TQVRVVSRVGVGYDSVNVPAATEQNIAVCRTPGTLHQSVVEHTI 107
Query: 404 TLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNI 583
++L + R+V+ + ++AG WDR G GKTL I+G G +G+EVA GM +
Sbjct: 108 GMILAIYRNVISQNKQVRAGDWDRT--AGPRAYGKTLGIIGYGVIGKEVAKAAVLLGMQV 165
Query: 584 IGFDPFVSADQCAQFHCTKMELEDIWPLADYITLHTPLIXSTRNFINA 727
I +DP A ++ ++ L++IW +D ++LH P T INA
Sbjct: 166 IAYDPIAPAGGPSEVE--RVALDEIWRRSDVVSLHAPCTPETERIINA 211
>UniRef50_Q27SN5 Cluster: Beta xylosidase-like protein; n=1;
Acanthamoeba castellanii|Rep: Beta xylosidase-like
protein - Acanthamoeba castellanii (Amoeba)
Length = 222
Score = 106 bits (254), Expect = 6e-22
Identities = 57/194 (29%), Positives = 102/194 (52%), Gaps = 5/194 (2%)
Frame = +2
Query: 164 TKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKK 343
T+ + +EE+L ++ + DA++ + E++ G KLKV+ GAG D +DV +A ++
Sbjct: 7 TEDYMPREEVLHKVTDVDAIICHGKDKADAELVAKGSKLKVISNFGAGYDTVDVKAATER 66
Query: 344 GVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDR-----ALYTGSELAGK 508
+ V N PGA + ++ L+L R A L+ G W+R + G+ GK
Sbjct: 67 NIWVCNTPGAVTNATADVALYLLLAACRRATEAERFLRDGSWERQGSDILAFWGNNPEGK 126
Query: 509 TLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYITLH 688
TL I+G+G +G+ +A R A M +I + + + T ++D+ +D+I++H
Sbjct: 127 TLGIIGMGNIGKALAKRAAALDMRVIYYKR-TPLPKEEENGATYKSMDDLLAESDFISIH 185
Query: 689 TPLIXSTRNFINAD 730
TPL +TR+ + D
Sbjct: 186 TPLTDATRHILGRD 199
>UniRef50_Q81N95 Cluster: D-3-phosphoglycerate dehydrogenase,
putative; n=19; Bacteria|Rep: D-3-phosphoglycerate
dehydrogenase, putative - Bacillus anthracis
Length = 390
Score = 105 bits (253), Expect = 9e-22
Identities = 63/184 (34%), Positives = 102/184 (55%), Gaps = 13/184 (7%)
Frame = +2
Query: 209 NH-DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALS 385
NH D +++RS + +E LK + RAGAGV+NI V+ +KG+ V N PGANA +
Sbjct: 30 NHPDGILLRSYSLHQEEF---SKDLKAIARAGAGVNNIPVERCTEKGIVVFNTPGANANA 86
Query: 386 ACELTCTLMLVLARHVVPASTALKAGRWD---------RALYTGSELAGKTLAILGLGRV 538
EL +++ +R+++ + K + + + GSE+AGK L ++GLG +
Sbjct: 87 VKELIIASLIMSSRNIINGVSWTKNLEGEEVPQLVESGKKQFVGSEIAGKRLGVIGLGAI 146
Query: 539 GREVATRMYAFGMNIIGFDPFVSADQCAQF--HCTK-MELEDIWPLADYITLHTPLIXST 709
G VA A GM+++G+DP++S + + H + L++I+ DYITLH PL T
Sbjct: 147 GALVANDALALGMDVVGYDPYISVETAWRLSTHVQRAFSLDEIFATCDYITLHIPLTNQT 206
Query: 710 RNFI 721
+ I
Sbjct: 207 KGMI 210
>UniRef50_Q1FF19 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding; n=1;
Clostridium phytofermentans ISDg|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, catalytic region:D- isomer
specific 2-hydroxyacid dehydrogenase, NAD-binding -
Clostridium phytofermentans ISDg
Length = 316
Score = 105 bits (253), Expect = 9e-22
Identities = 67/213 (31%), Positives = 106/213 (49%), Gaps = 2/213 (0%)
Frame = +2
Query: 95 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 274
+LI V L G S E + I + L++R+ TKEV DA
Sbjct: 5 ILIPQDVDESGKNYLQEKGYELRILQDSSIENICNNIGDCSGLLLRTVP-CTKEVFDAAP 63
Query: 275 KLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL 454
LKV+GR G G DNID+ A +G+ V P ANA S E T L+L A+++V A L
Sbjct: 64 HLKVIGRHGVGYDNIDIAEATAQGIKVCYTPLANANSVAEHTIMLLLACAKNIVIADKEL 123
Query: 455 KAGRWD-RALYTGSELAGKTLAILGLGRVGREVATR-MYAFGMNIIGFDPFVSADQCAQF 628
+ G ++ R G ++ GKTL I+G GR+G+ VA + GM I+ + + + +
Sbjct: 124 RQGNYEIRNQMPGIDVFGKTLGIIGFGRIGKSVAKKAALGLGMKILAYGRGLEIKEVPDY 183
Query: 629 HCTKMELEDIWPLADYITLHTPLIXSTRNFINA 727
E++++ +D+I+LH P + F+++
Sbjct: 184 VTIIKEVDELIRQSDFISLHMPYSKEMQGFMDS 216
>UniRef50_P0A9T3 Cluster: D-3-phosphoglycerate dehydrogenase; n=185;
Bacteria|Rep: D-3-phosphoglycerate dehydrogenase -
Shigella flexneri
Length = 410
Score = 105 bits (253), Expect = 9e-22
Identities = 65/213 (30%), Positives = 110/213 (51%), Gaps = 3/213 (1%)
Frame = +2
Query: 98 LIVDGVGAKCAELLNAYGIATTT--KAKISKEELLMEIPNHDALVVRSATQVTKEVLDAG 271
L+V+GV K E L A G K + E+L I + + +RS T +T++V++A
Sbjct: 14 LLVEGVHQKALESLRAAGYTNIEFHKGALDDEQLKESIRDAHFIGLRSRTHLTEDVINAA 73
Query: 272 VKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTA 451
KL +G G + +D+D+A K+G+ V NAP +N S EL +L+L R V A+
Sbjct: 74 EKLVAIGCFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEANAK 133
Query: 452 LKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFH 631
G W++ E GK L I+G G +G ++ + GM + +D ++ +
Sbjct: 134 AHRGVWNKLAAGSFEARGKKLGIIGYGHIGTQLGILAESLGMYVYFYD---IENKLPLGN 190
Query: 632 CTKME-LEDIWPLADYITLHTPLIXSTRNFINA 727
T+++ L D+ ++D ++LH P ST+N + A
Sbjct: 191 ATQVQHLSDLLNMSDVVSLHVPENPSTKNMMGA 223
>UniRef50_Q82U25 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase; n=3; Nitrosomonadaceae|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase - Nitrosomonas
europaea
Length = 311
Score = 105 bits (251), Expect = 1e-21
Identities = 59/186 (31%), Positives = 98/186 (52%)
Frame = +2
Query: 173 KISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVG 352
K++++E++ + N ++ +T+ VL + L+V+ R G G+DN+D+++A + +
Sbjct: 37 KLTEDEIITLLGNDTVALLAGVEPLTEHVLTSASALRVIARCGTGMDNVDLEAARRLNIQ 96
Query: 353 VINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLG 532
V N P A A + ELT LML R + +++ G W R+ G LA +T+ I+GLG
Sbjct: 97 VSNTPEAPAQAVAELTLGLMLDCLRQINRIDRSVRQGEWPRS--QGRLLAARTVGIVGLG 154
Query: 533 RVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYITLHTPLIXSTR 712
+GR VA AFG +I DP + Q A + L + AD +TLH P +
Sbjct: 155 HIGRRVAKLCQAFGAQVIAHDPHL---QLAPDGVELVALTTLLEQADLVTLHLPYSPAVH 211
Query: 713 NFINAD 730
I+A+
Sbjct: 212 YLIDAE 217
>UniRef50_A0JVX0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Arthrobacter sp.
FB24|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Arthrobacter sp. (strain FB24)
Length = 319
Score = 105 bits (251), Expect = 1e-21
Identities = 53/151 (35%), Positives = 87/151 (57%)
Frame = +2
Query: 242 QVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVL 421
+++ +VL+ +LK + R G GVD+IDV++A + G+ V+ APGAN+ ELT L+L
Sbjct: 72 RLSGQVLEDLTRLKAISRNGVGVDSIDVEAAERLGINVLTAPGANSQGVAELTIALILAG 131
Query: 422 ARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPF 601
+R + LK+G+W+R G+E++GK L ++G G++GR VAT GM +I FD +
Sbjct: 132 SRSIPWHDAQLKSGQWNRR--PGNEVSGKVLGLIGCGQIGRRVATMALGLGMKVIAFDEY 189
Query: 602 VSADQCAQFHCTKMELEDIWPLADYITLHTP 694
+ E + + ++LHTP
Sbjct: 190 PVTSFAPSPDFSWAPRERVLSSSHVVSLHTP 220
>UniRef50_A0HBX6 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Comamonas testosteroni
KF-1|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Comamonas testosteroni KF-1
Length = 320
Score = 105 bits (251), Expect = 1e-21
Identities = 60/171 (35%), Positives = 90/171 (52%)
Frame = +2
Query: 218 ALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACEL 397
ALV+R + V+ VL A L++V + GAGVD++D+++A +GV V A ANA + E
Sbjct: 55 ALVLRGSKPVSAAVLRAAPALRIVAKNGAGVDSVDMEAARTQGVAVAVAQAANAPAVAEH 114
Query: 398 TCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGM 577
LML L R + ++AG W + + G + G T+ I+G G +GR A A G
Sbjct: 115 ALALMLALVRQLPQLDQQVRAGGWAGSNWQGRDFRGSTVGIVGYGAIGRATAQLAAALGA 174
Query: 578 NIIGFDPFVSADQCAQFHCTKMELEDIWPLADYITLHTPLIXSTRNFINAD 730
++ P A Q F C + +L + P D ++LH PL TR I A+
Sbjct: 175 KVLVLRP---AGQADDFDC-EPDLRRLLPRVDILSLHCPLTEQTRGLIGAN 221
>UniRef50_A1W9A3 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Acidovorax sp.
JS42|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Acidovorax sp. (strain JS42)
Length = 339
Score = 104 bits (250), Expect = 2e-21
Identities = 56/171 (32%), Positives = 92/171 (53%)
Frame = +2
Query: 215 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 394
+ L V T+V + VL +L++V AG D+ID+++ K+G+ V + P + S E
Sbjct: 51 EVLCVFVRTRVDESVLRMLPRLRLVATRSAGFDHIDLEACRKRGIAVCHVPDYGSASVAE 110
Query: 395 LTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFG 574
L+L + RH+ A + G + TG EL G+TL I+GLGR+GR VA FG
Sbjct: 111 HAFALLLGVTRHLTQAHERARQGSFAYRGLTGFELEGRTLGIVGLGRIGRHVARIAVGFG 170
Query: 575 MNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYITLHTPLIXSTRNFINA 727
M+++ +DP +A + + E + +D ++LH P +TR+ I+A
Sbjct: 171 MDVLAYDPAFAASAARPAGVSLVTWEQVLQGSDILSLHVPATEATRHLIDA 221
>UniRef50_Q7UQC8 Cluster: Probable 2-hydroxyacid dehydrogenase; n=1;
Pirellula sp.|Rep: Probable 2-hydroxyacid dehydrogenase
- Rhodopirellula baltica
Length = 406
Score = 104 bits (249), Expect = 3e-21
Identities = 60/189 (31%), Positives = 102/189 (53%), Gaps = 5/189 (2%)
Frame = +2
Query: 179 SKEELLMEIPNHDALVVRSATQVTKEVLD-AGVKLKVVGRAGAGVDNIDVDSAGKKGVGV 355
S+EEL + L+ + ++ E++D AG +L VV G +NIDVD+A +GV V
Sbjct: 120 SREELCRLVKGRHGLLTMLSDRIDGELMDVAGEQLCVVSNYAVGFNNIDVDAAKTRGVVV 179
Query: 356 INAPGANALSACELTCTLMLVLARHVVPASTALKAGR---WDRALYTGSELAGKTLAILG 526
N P + +L +L+ +RHV+PA ++ G W+ + G E + KTL I+G
Sbjct: 180 GNTPDVLTDATADLAVSLLFAASRHVLPAGNQVREGEWKTWEPTGWLGVEPSDKTLGIVG 239
Query: 527 LGRVGREVATRMY-AFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYITLHTPLIX 703
+GR+G+ A R+ +GMN++ D + ++EL+ + +D++++H L
Sbjct: 240 MGRIGKATAKRLVGGWGMNLLYTSRSDQGDVEKELGGRRVELDTLLAESDFVSVHVALTD 299
Query: 704 STRNFINAD 730
TRN I+AD
Sbjct: 300 ETRNLIDAD 308
>UniRef50_Q8EP33 Cluster: Glycerate dehydrogenase; n=2;
Bacillaceae|Rep: Glycerate dehydrogenase -
Oceanobacillus iheyensis
Length = 314
Score = 103 bits (248), Expect = 3e-21
Identities = 63/201 (31%), Positives = 100/201 (49%), Gaps = 2/201 (0%)
Frame = +2
Query: 131 ELLNAYGIATT--TKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGA 304
E LN G T T I KE+L + + +++ + Q+ KE++DA LK + + GA
Sbjct: 20 ENLNRLGNVTILDTDNGIEKEKLKQAVREVE-VIITAVVQIDKEIIDAAPNLKYIMKFGA 78
Query: 305 GVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALY 484
G DNID A +KG+ V N PG NA + +L LML AR++ + L+ G W+ L
Sbjct: 79 GYDNIDFKYAREKGIPVTNTPGQNADAVADLAIGLMLATARNIPAKNEELRNGNWE--LS 136
Query: 485 TGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWP 664
G E+ K L I+G G +G+ +A R F M ++ + F + + ++L +
Sbjct: 137 MGIEIFQKKLGIIGFGAIGQAIAQRATGFQMEVLAYGTFQDQTIADRLNVEFVDLNKLLN 196
Query: 665 LADYITLHTPLIXSTRNFINA 727
+D + + T L INA
Sbjct: 197 ESDIVVVSTTLRKDNYQLINA 217
>UniRef50_Q3DL54 Cluster: Glyoxylate reductase, NADH-dependent; n=9;
Streptococcus|Rep: Glyoxylate reductase, NADH-dependent
- Streptococcus agalactiae 515
Length = 318
Score = 103 bits (248), Expect = 3e-21
Identities = 62/223 (27%), Positives = 114/223 (51%), Gaps = 5/223 (2%)
Frame = +2
Query: 80 VDIKSVLIVDGVGAK-CAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKE 256
+D K +L+ V + +L++ + + + S++ +L + +D ++ + KE
Sbjct: 1 MDKKKILVTGTVPKEGLRKLMDRFDVTYSEDRPFSRDYVLEHLSEYDGWLLMGQ-KGDKE 59
Query: 257 VLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVV 436
++DAG L+++ G D++D A +KG+ V N+P A + E+T L+L ++ +
Sbjct: 60 MIDAGENLQIISLNAVGFDHVDTAYAKEKGIIVSNSPQAVRVPTAEMTFALILAASKRLA 119
Query: 437 PASTALKAGRW---DRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPF-V 604
+ +++G W Y G L G TL I G+GR+G VA AFGM ++ D + +
Sbjct: 120 FYDSIVRSGEWIDPSEQRYQGLTLQGSTLGIYGMGRIGLTVANFAKAFGMTVVYNDVYRL 179
Query: 605 SADQCAQFHCTKMELEDIWPLADYITLHTPLIXSTRNFINADV 733
D+ + T +E + + AD IT+H P + ST + N DV
Sbjct: 180 PEDKEKELGVTYLEFDQLIKTADVITIHAPALPSTIHKFNKDV 222
>UniRef50_Q63VJ5 Cluster: D-3-phosphoglycerate dehydrogenase; n=8;
Burkholderiaceae|Rep: D-3-phosphoglycerate dehydrogenase
- Burkholderia pseudomallei (Pseudomonas pseudomallei)
Length = 424
Score = 103 bits (247), Expect = 5e-21
Identities = 61/189 (32%), Positives = 89/189 (47%)
Frame = +2
Query: 167 KAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKG 346
K ++ EL + H + +RSAT + ++ +DA L +G G +D+ +A G
Sbjct: 52 KGALAGAELRRALQQHQLIGIRSATHLLRDEIDAARHLLAIGCFCIGTSQVDLPAAAHHG 111
Query: 347 VGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILG 526
+ V NAP +N S EL ++L R V S AG W + E GKT+AI+G
Sbjct: 112 IPVFNAPFSNTRSVAELVIAEAILLLRRVPEKSVLAHAGEWAKGAGGSFEARGKTIAIVG 171
Query: 527 LGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYITLHTPLIXS 706
G +G +V A GM ++ +D V A L + LAD +TLH P S
Sbjct: 172 YGNIGAQVGVLAEALGMRVVYYD--VQAKLSLGSAQPARSLGEAIALADVVTLHVPAHAS 229
Query: 707 TRNFINADV 733
T N I+A V
Sbjct: 230 THNMIDASV 238
>UniRef50_A5Z3X2 Cluster: Putative uncharacterized protein; n=1;
Eubacterium ventriosum ATCC 27560|Rep: Putative
uncharacterized protein - Eubacterium ventriosum ATCC
27560
Length = 387
Score = 103 bits (247), Expect = 5e-21
Identities = 66/186 (35%), Positives = 93/186 (50%), Gaps = 14/186 (7%)
Frame = +2
Query: 215 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 394
D +VRSA LD L + RAGAGV+NI +D KGV V N PGANA E
Sbjct: 32 DVALVRSAAM---HDLDLPESLLAIARAGAGVNNIPLDKCADKGVVVFNTPGANANGVKE 88
Query: 395 LTCTLMLVLARHVVPAS----------TALKAGRWDRALYTGSELAGKTLAILGLGRVGR 544
L ML+ +R ++ + K + + G+E+ GK L ++GLG +GR
Sbjct: 89 LVLCGMLLASRDIIGGNKWVANNTDNENISKDMEKAKKNFAGNEIKGKKLGVIGLGAIGR 148
Query: 545 EVATRMYAFGMNIIGFDPFVSADQCAQF----HCTKMELEDIWPLADYITLHTPLIXSTR 712
VA + GM + G DPF+S + H K E+I+ D+IT+HTPL+ T+
Sbjct: 149 LVANAAESMGMEVYGNDPFISVEGALSLKRDVHLVKTR-EEIFKECDFITVHTPLVDDTK 207
Query: 713 NFINAD 730
IN +
Sbjct: 208 KMINKE 213
>UniRef50_Q72KT6 Cluster: Glycerate dehydrogenase/glyoxylate
reductase; n=2; Thermus thermophilus|Rep: Glycerate
dehydrogenase/glyoxylate reductase - Thermus
thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)
Length = 338
Score = 103 bits (246), Expect = 6e-21
Identities = 59/188 (31%), Positives = 96/188 (51%), Gaps = 3/188 (1%)
Frame = +2
Query: 176 ISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGV 355
+ K ELL + L+ ++ EV+D LKV+ GVD++D+++A ++G+ V
Sbjct: 59 LPKAELLKRVEGAVGLIPTVEDRIDAEVMDRAKGLKVIACYSVGVDHVDLEAARERGIRV 118
Query: 356 INAPGANALSACELTCTLMLVLARHVVPASTALKAG---RWDRALYTGSELAGKTLAILG 526
+ PG + +LT L+L +AR VV + + G W L G +L G TL ++G
Sbjct: 119 THTPGVLTEATADLTLALLLAVARRVVEGAAYARDGLWRAWHPELLLGLDLQGLTLGLVG 178
Query: 527 LGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYITLHTPLIXS 706
+GR+G+ VA R AFGM ++ A + LE++ AD ++LHTPL
Sbjct: 179 MGRIGQAVAKRALAFGMRVV-----YHARTPKPLPYPFLSLEELLKEADVVSLHTPLTPE 233
Query: 707 TRNFINAD 730
T +N +
Sbjct: 234 THRLLNRE 241
>UniRef50_A3UGW9 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Proteobacteria|Rep: D-3-phosphoglycerate dehydrogenase -
Oceanicaulis alexandrii HTCC2633
Length = 407
Score = 103 bits (246), Expect = 6e-21
Identities = 66/216 (30%), Positives = 107/216 (49%), Gaps = 3/216 (1%)
Frame = +2
Query: 92 SVLIVDGVGAKCAELLNAYGIATTTKAKISKE--ELLMEIPNHDALVVRSATQVTKEVLD 265
+ L+++ V L G T + S + +L EI + L +RS T V +LD
Sbjct: 8 TALLLENVHPDADNALQTAGPVTVKRLSGSPDRAQLESEIASASVLGIRSRTHVDAALLD 67
Query: 266 AGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPAS 445
A +L+ VG G + +D+ +A ++GV V NAP AN S ELT +++L R +
Sbjct: 68 AAKELQAVGCFCIGTNQVDLVAAAERGVPVFNAPFANTRSVAELTMASVIMLMRRIPEKM 127
Query: 446 TALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQ 625
A++ G W + +E+ K L I+G G +G +++ A GM++ +D A + A
Sbjct: 128 FAIQRGEWLKTADGANEVRKKKLGIIGYGNIGAQLSVIASALGMHVYYYD---IAPKLAH 184
Query: 626 FHCTKME-LEDIWPLADYITLHTPLIXSTRNFINAD 730
+ M+ L+DI D +TLH P T+N I D
Sbjct: 185 GNARPMDTLDDILTECDVVTLHVPSTPRTKNMIGKD 220
>UniRef50_Q4AIL7 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding precursor; n=1;
Chlorobium phaeobacteroides BS1|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, catalytic region:D- isomer
specific 2-hydroxyacid dehydrogenase, NAD-binding
precursor - Chlorobium phaeobacteroides BS1
Length = 312
Score = 102 bits (245), Expect = 8e-21
Identities = 56/207 (27%), Positives = 98/207 (47%)
Frame = +2
Query: 89 KSVLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDA 268
+ VL +D LL G + +++ L + +V+RS ++ E L +
Sbjct: 4 RKVLFIDSAHPSLTLLLQELGFTCDYFPEYKRDDYLKIASQYLGVVIRSKIKIDAEFLSS 63
Query: 269 GVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPAST 448
+L+ + R GAG++NID+ SA K V +NAP N + E ++L L ++ A
Sbjct: 64 ATQLRFIARVGAGMENIDIQSADKHQVVCLNAPEGNRDAVAEQAVGMILTLFNRLLIADA 123
Query: 449 ALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQF 628
++ G W R G EL GKT+ I+G G G A ++ F + I+ +D + +
Sbjct: 124 EVRKGIWLREQNRGIELGGKTVGIIGYGNTGSAFARKLQGFDVRILAYDKYKTG--FGNS 181
Query: 629 HCTKMELEDIWPLADYITLHTPLIXST 709
+ +++I+ AD ++ H PL T
Sbjct: 182 FVKEATMDEIYQQADILSFHVPLTEET 208
>UniRef50_A7IJ69 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=2; Rhizobiales|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase
NAD-binding - Xanthobacter sp. (strain Py2)
Length = 359
Score = 102 bits (245), Expect = 8e-21
Identities = 58/161 (36%), Positives = 91/161 (56%)
Frame = +2
Query: 245 VTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLA 424
VT++VL A +LKV+ R G G D +DVD+A G V A GAN + + T LML +
Sbjct: 94 VTRDVLAAHPQLKVIARRGVGYDRVDVDAARDLGRVVTIAAGANDPAVADHTIALMLAVL 153
Query: 425 RHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFV 604
R + + A+ G W R L G++L GKT+ ++G GR+GR+VA R+ F + ++
Sbjct: 154 RRLKASQAAIARGDW-RVL-VGADLTGKTVGLIGFGRIGRQVARRLSGFDVTVLVTSRTP 211
Query: 605 SADQCAQFHCTKMELEDIWPLADYITLHTPLIXSTRNFINA 727
+ T + L+++ +D ++LH PL+ TR+ INA
Sbjct: 212 DPEAAG---VTFVALDELIARSDVVSLHAPLVPETRHVINA 249
>UniRef50_A4FK85 Cluster: D-3-phosphoglycerate dehydrogenase,
putative; n=1; Saccharopolyspora erythraea NRRL
2338|Rep: D-3-phosphoglycerate dehydrogenase, putative -
Saccharopolyspora erythraea (strain NRRL 23338)
Length = 352
Score = 102 bits (245), Expect = 8e-21
Identities = 62/199 (31%), Positives = 94/199 (47%), Gaps = 4/199 (2%)
Frame = +2
Query: 146 YGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDV 325
+G K EE L+E + + T +VL L+ VG G N+D+
Sbjct: 44 FGPVGNVKEASGTEEQLLESLSGVQIAATQMAPFTADVLAKSPDLRFVGVCRGGPVNVDL 103
Query: 326 DSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYT----GS 493
+A + GV V APG NA +A E L+L R + + LK+G W Y G
Sbjct: 104 QAATEAGVVVSYAPGRNAAAAAEFAVGLVLAALRRIPASDAELKSGNWRGDYYAYENAGI 163
Query: 494 ELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLAD 673
EL G T+ ++G G +GR VA + AFG +++ DPFV + +ELE++ +
Sbjct: 164 ELEGSTVGLVGYGAIGRIVARVLAAFGAHVLVADPFVKPEDATADGVELVELEELLRRSS 223
Query: 674 YITLHTPLIXSTRNFINAD 730
++LH L T + +NAD
Sbjct: 224 VVSLHARLTPETHHLLNAD 242
>UniRef50_Q1WVK4 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Lactobacillus salivarius subsp. salivarius UCC118|Rep:
D-3-phosphoglycerate dehydrogenase - Lactobacillus
salivarius subsp. salivarius (strain UCC118)
Length = 394
Score = 102 bits (244), Expect = 1e-20
Identities = 65/184 (35%), Positives = 96/184 (52%), Gaps = 12/184 (6%)
Frame = +2
Query: 215 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 394
DAL++RS G + + RAGAGV+NI ++ A +G V N PG+NA + E
Sbjct: 32 DALLIRSQDM---HKTPFGTSVLAIARAGAGVNNIPLEKATSQGTAVFNTPGSNANAVKE 88
Query: 395 LTCTLMLVLARHVVPA-STALKAGRWDRALYT--------GSELAGKTLAILGLGRVGRE 547
L T++L+ R V + A K D +L T G+EL GK + I+GLG +G
Sbjct: 89 LIITMLLLSVRPVFASVKWAQKLAGADVSLQTEKGKNHFAGTELYGKKIGIIGLGNIGSR 148
Query: 548 VATRMYAFGMNIIGFDPFVSADQCAQF--HCTKME-LEDIWPLADYITLHTPLIXSTRNF 718
VA GM +IG+DP++S ++ Q + E LE++ +D+IT+H P RN
Sbjct: 149 VAKACMDLGMKVIGYDPYISVEKAWQLSNDIPRAESLEELLEQSDFITIHIPYTDKNRNI 208
Query: 719 INAD 730
I D
Sbjct: 209 IGED 212
>UniRef50_UPI000023F60F Cluster: hypothetical protein FG08018.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG08018.1 - Gibberella zeae PH-1
Length = 901
Score = 101 bits (243), Expect = 1e-20
Identities = 60/173 (34%), Positives = 90/173 (52%), Gaps = 3/173 (1%)
Frame = +2
Query: 221 LVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELT 400
L+VRS+ ++++ L +G+ G G+D IDVD+ +G+ + N PG NA + EL
Sbjct: 61 LLVRSSRLTAQDIISCP-NLVAIGKQGVGLDKIDVDACASRGIKIFNTPGVNARAVAELV 119
Query: 401 CTLMLVLARHVVPASTALKAG-RWDRALYTGSELAGKTLAILGLGRVGREVATRMY-AFG 574
TL AR V +G + +G L KT+ ILG+G +G+ VA AF
Sbjct: 120 LTLATASARQVGSIIAKQSSGILVPKEKCSGLILHEKTIGILGMGNIGKCVAKIFRGAFD 179
Query: 575 MNIIGFDPFVSADQCAQF-HCTKMELEDIWPLADYITLHTPLIXSTRNFINAD 730
N+I +DPF+ AD + H +E++ +D IT+H PL TRN I D
Sbjct: 180 ANVIAYDPFLPADAWEEIPHKRATSVEEVLRSSDVITVHMPLTPETRNLIGYD 232
>UniRef50_A1JTE6 Cluster: Putative oxidoreductase; n=1; Yersinia
enterocolitica subsp. enterocolitica 8081|Rep: Putative
oxidoreductase - Yersinia enterocolitica serotype O:8 /
biotype 1B (strain 8081)
Length = 338
Score = 101 bits (242), Expect = 2e-20
Identities = 73/209 (34%), Positives = 110/209 (52%), Gaps = 23/209 (11%)
Frame = +2
Query: 167 KAKISKEELLMEIPNHDA-LVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKK 343
K K+S+E+L+ HDA +V S +T V+ A +LK++ A NIDV++A ++
Sbjct: 31 KPKLSEEQLIAL--GHDADFLVTSYDDITARVIKACPQLKLIACTRANPVNIDVNAATER 88
Query: 344 GVGVINAPGANALSACELTCTLMLVLARHVVPASTALK-----------AGR-----WD- 472
G+ V+ PG N+ +A ELT LML LARH+ A +ALK AG WD
Sbjct: 89 GIPVVYTPGRNSDAAAELTIALMLNLARHIPQAHSALKQRQFTATTPGNAGLKTDVVWDV 148
Query: 473 -----RALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCT 637
++ G EL KTL I+G G +G+ V AFGM ++ DP+VS + +
Sbjct: 149 TKDSPYEVFKGVELRNKTLGIVGYGSIGQRVGRIARAFGMQLLVADPYVSEVELDEPGIH 208
Query: 638 KMELEDIWPLADYITLHTPLIXSTRNFIN 724
K LE ++ +D++TLH + T I+
Sbjct: 209 KTTLERLFSQSDFVTLHVKVTPQTVGLID 237
>UniRef50_A0GVM6 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Burkholderia
phytofirmans PsJN|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Burkholderia phytofirmans
PsJN
Length = 327
Score = 101 bits (241), Expect = 2e-20
Identities = 60/187 (32%), Positives = 102/187 (54%), Gaps = 2/187 (1%)
Frame = +2
Query: 179 SKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVI 358
S+E L + + DAL+VR ++ ++ D +LK R G G+D I V+ A + + V
Sbjct: 34 SEETLRKFVADADALIVR--VRLPDDIFDHAPRLKACVRHGVGLDFIPVERATRADIAVA 91
Query: 359 NAPGANALSACELTCTLMLVLARHVVPASTALKAGRW-DRALYTGSELAGKTLAILGLGR 535
N P +N + E +L +AR A + W R + G EL +T+ I+GLGR
Sbjct: 92 NLPDSNTQAVAEHVVGAILAMARGFDRLPRAWRNDGWLVRQTFQGIELRDRTVGIVGLGR 151
Query: 536 VGREVATRMY-AFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYITLHTPLIXSTR 712
+G +VA ++ FGM ++G D A + + + +E+++ +D+ITLH PL+ STR
Sbjct: 152 IGLQVAAALHHGFGMRVLGCDN--GAREGLPSYVDQTSIENVFSGSDFITLHAPLVKSTR 209
Query: 713 NFINADV 733
+ +NA++
Sbjct: 210 HLVNAEL 216
>UniRef50_UPI00015BD3AA Cluster: UPI00015BD3AA related cluster; n=1;
unknown|Rep: UPI00015BD3AA UniRef100 entry - unknown
Length = 332
Score = 100 bits (240), Expect = 3e-20
Identities = 58/179 (32%), Positives = 94/179 (52%), Gaps = 1/179 (0%)
Frame = +2
Query: 197 MEIPNH-DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGA 373
+EIP+ + L V ++++K+V+D+ LK++ G D+IDV A KG+ V N P
Sbjct: 38 VEIPDDIEILSVFIYSKISKDVIDSLPDLKLIATRSTGFDHIDVAYANSKGITVCNVPSY 97
Query: 374 NALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVA 553
S E LML LAR + ++ G + + G ELAGKTL ++G GR+G A
Sbjct: 98 GEESVSEYAIMLMLALARKLRETIDNVEKGVYKTSNLRGIELAGKTLGVIGTGRIGARTA 157
Query: 554 TRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYITLHTPLIXSTRNFINAD 730
FGM+++ +D + ++ ++ ++D+ITLH P + ST + IN D
Sbjct: 158 LLARCFGMDVVCYDARQN-QILIDAGIKYLDFNELLSVSDFITLHVPYLPSTHHLINMD 215
>UniRef50_A4AN91 Cluster: Predicted dehydrogenase; n=14;
Bacteroidetes|Rep: Predicted dehydrogenase -
Flavobacteriales bacterium HTCC2170
Length = 337
Score = 100 bits (240), Expect = 3e-20
Identities = 55/182 (30%), Positives = 94/182 (51%)
Frame = +2
Query: 179 SKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVI 358
SKE++ I +D + +RS + KE + LK +GR GAG++NIDV A KK + +
Sbjct: 56 SKEQIEHRIGEYDGITIRSRFTIDKEFIKKAKNLKFIGRVGAGLENIDVAYAKKKNIFLA 115
Query: 359 NAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRV 538
AP N + E T ++L L ++ A+ ++ G+WDR G EL GKT+ I+G G +
Sbjct: 116 AAPEGNRNAVGEHTLGMLLSLFNNLNKANLEVRNGKWDREGNRGVELDGKTVGIIGYGNM 175
Query: 539 GREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYITLHTPLIXSTRNF 718
G+ A ++ F + ++ +D + ++ + ++ D ++LH P T
Sbjct: 176 GKAFAKKLRGFDVEVLCYD---IVGGVGDENARQVGIMELQQKTDVLSLHVPQTPETTGM 232
Query: 719 IN 724
IN
Sbjct: 233 IN 234
>UniRef50_P40054 Cluster: D-3-phosphoglycerate dehydrogenase 1;
n=35; Eukaryota|Rep: D-3-phosphoglycerate dehydrogenase
1 - Saccharomyces cerevisiae (Baker's yeast)
Length = 469
Score = 100 bits (240), Expect = 3e-20
Identities = 61/217 (28%), Positives = 112/217 (51%), Gaps = 2/217 (0%)
Frame = +2
Query: 83 DIKSVLIVDGVGAKCAELLNAYGIATTT-KAKISKEELLMEIPNHDALVVRSATQVTKEV 259
D+K +L+++ V + G K+ + +EEL+ +I + A+ +RS T++T V
Sbjct: 58 DMK-ILLLENVNQTAITIFEEQGYQVEFYKSSLPEEELIEKIKDVHAIGIRSKTRLTSNV 116
Query: 260 LDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVP 439
L L +G G + +D+D A +G+ V N+P +N+ S EL ++ LAR +
Sbjct: 117 LQHAKNLVCIGCFCIGTNQVDLDYATSRGIAVFNSPFSNSRSVAELVIAEIISLARQLGD 176
Query: 440 ASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFD-PFVSADQ 616
S L G W++ E+ GKTL I+G G +G +++ A G++++ +D + A
Sbjct: 177 RSIELHTGTWNKVAARCWEVRGKTLGIIGYGHIGSQLSVLAEAMGLHVLYYDIVTIMALG 236
Query: 617 CAQFHCTKMELEDIWPLADYITLHTPLIXSTRNFINA 727
A+ T L+++ +D++TLH P T ++A
Sbjct: 237 TARQVST---LDELLNKSDFVTLHVPATPETEKMLSA 270
>UniRef50_Q5FUW5 Cluster: D-3-phosphoglycerate dehydrogenase; n=55;
Bacteria|Rep: D-3-phosphoglycerate dehydrogenase -
Gluconobacter oxydans (Gluconobacter suboxydans)
Length = 416
Score = 100 bits (239), Expect = 4e-20
Identities = 62/207 (29%), Positives = 103/207 (49%), Gaps = 2/207 (0%)
Frame = +2
Query: 95 VLIVDGVGAKCAELLNAYGIATTTKAKISKE-ELLMEIPNHDALV-VRSATQVTKEVLDA 268
+L+++G+ A A G T+ K + E + L E +V +RS TQ+T+EVL+
Sbjct: 14 ILLLEGIHESAAAHFAAEGYTEVTRVKGALEGDALKEALQGVHMVGIRSRTQLTREVLEG 73
Query: 269 GVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPAST 448
+L +G G + +D+++A G+ V NAP +N S EL +++L R + S
Sbjct: 74 ADRLMAIGCFCIGTNQVDLNAARMLGIPVFNAPFSNTRSVAELVMGEIVMLLRRIPSRSE 133
Query: 449 ALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQF 628
A G WD++ E+ GKTL I+G G +G +++ AFGM ++ FD
Sbjct: 134 ACHKGGWDKSATNAWEVRGKTLGIVGYGSIGSQLSVLAEAFGMRVLYFDVMPRLPHGNAI 193
Query: 629 HCTKMELEDIWPLADYITLHTPLIXST 709
+ L D+ +D ++LH P T
Sbjct: 194 AVS--TLHDLLAQSDIVSLHVPQTPET 218
>UniRef50_Q01W77 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Solibacter usitatus
Ellin6076|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Solibacter usitatus (strain
Ellin6076)
Length = 312
Score = 99 bits (238), Expect = 6e-20
Identities = 60/170 (35%), Positives = 90/170 (52%)
Frame = +2
Query: 218 ALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACEL 397
AL +RS+++ T+ V A KL++V G G D++D+ +A + GV V N PG A S E
Sbjct: 52 ALNIRSSSRFTERVFAACPKLRMVSIWGTGTDHVDLAAAARHGVTVANTPGVAARSIAEH 111
Query: 398 TCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGM 577
T L+ +AR + A + G W+R EL GKT ++G G VGR A A GM
Sbjct: 112 TLALLFAVARQIPHMDAATRRGAWERG--QSMELYGKTCGVIGYGAVGRHFARLATAIGM 169
Query: 578 NIIGFDPFVSADQCAQFHCTKMELEDIWPLADYITLHTPLIXSTRNFINA 727
++ + SA +F LED++ +D I++H L T++FI A
Sbjct: 170 RVMQWTLHPSAYPDVEF----ASLEDLYRASDVISVHLRLSPDTQDFIAA 215
>UniRef50_A6T665 Cluster: Putative D-3-phosphoglycerate
dehydrogenase; n=1; Klebsiella pneumoniae subsp.
pneumoniae MGH 78578|Rep: Putative D-3-phosphoglycerate
dehydrogenase - Klebsiella pneumoniae subsp. pneumoniae
MGH 78578
Length = 342
Score = 99 bits (238), Expect = 6e-20
Identities = 72/213 (33%), Positives = 108/213 (50%), Gaps = 26/213 (12%)
Frame = +2
Query: 167 KAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKG 346
K K+S +L+ E+ + ++V S +VT V+ A +L+V+ A NID +A +G
Sbjct: 31 KPKLSAGQLI-ELAHDAEVLVTSYDEVTDAVMAACPRLQVIACTRANPVNIDTQAAQARG 89
Query: 347 VGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGR-------------------- 466
+ V+ PG NA +A ELT LML LARH+ + ALK G
Sbjct: 90 IRVLYTPGRNADAAAELTLGLMLSLARHIPQSHAALKRGEFTQADNASAATQQGLRRDVV 149
Query: 467 WDRA------LYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQF 628
WD + ++ GSEL KTL ++G G +GR VA AFGM ++ DPFV+A+ +
Sbjct: 150 WDVSPESPYEVFKGSELRNKTLGLVGYGNIGRRVARIARAFGMAVLVVDPFVAAEDINEP 209
Query: 629 HCTKMELEDIWPLADYITLHTPLIXSTRNFINA 727
K LE ++ AD ++LH + +NA
Sbjct: 210 GLQKTTLEALFREADIVSLHLSSGPHSDGLVNA 242
>UniRef50_A0Z6W9 Cluster: Spermidine/putrescine ABC transporter
ATP-binding subunit; n=4; Bacteria|Rep:
Spermidine/putrescine ABC transporter ATP-binding
subunit - marine gamma proteobacterium HTCC2080
Length = 395
Score = 99 bits (238), Expect = 6e-20
Identities = 64/193 (33%), Positives = 102/193 (52%), Gaps = 16/193 (8%)
Frame = +2
Query: 200 EIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANA 379
EI + DA+++RS E+ + + RAGAGV+NI + + G+ V N PGANA
Sbjct: 28 EIGSADAMLLRSHKLQADEI---SASVTAIARAGAGVNNIPLSHCTELGIPVFNTPGANA 84
Query: 380 LSACELTCTLMLVLARHV---VPASTALKAGRWDRAL----------YTGSELAGKTLAI 520
+ EL +L+ +R + + +L ++A+ + G+EL GKTL +
Sbjct: 85 NAVKELVAAGLLLASRDILGGIDFVNSLSEDLDEQAMGPLLEAEKKRFAGAELKGKTLGV 144
Query: 521 LGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPL---ADYITLHT 691
LGLG +G VA GM+++GFDP +S + Q + +E++ L ADYI++H
Sbjct: 145 LGLGAIGSLVAQLGLELGMDVVGFDPAISIEAAWQLPSSVKRMENMQALFSRADYISIHV 204
Query: 692 PLIXSTRNFINAD 730
P I ST + IN +
Sbjct: 205 PAIESTHHLINQE 217
>UniRef50_Q27SS3 Cluster: Glycerate dehydrogenase-like protein; n=2;
Eukaryota|Rep: Glycerate dehydrogenase-like protein -
Trimastix pyriformis
Length = 232
Score = 99 bits (238), Expect = 6e-20
Identities = 57/186 (30%), Positives = 98/186 (52%), Gaps = 3/186 (1%)
Frame = +2
Query: 179 SKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVI 358
+++EL+ D + + ++ +E+L+ +L+VV G +NID+ +A ++ V V
Sbjct: 34 TRDELVSGFQWADGALTMLSDKIDRELLEVAPRLRVVANYAVGYNNIDLTAANERHVVVT 93
Query: 359 NAPGANALSACELTCTLMLVLARHVVPASTALKAG---RWDRALYTGSELAGKTLAILGL 529
N P A + +LT L+L +AR +V ++AG W G +L GKTL I+GL
Sbjct: 94 NTPHCLAEATADLTMGLLLAVARRLVEGDGLVRAGLFKGWAPEFLLGMDLHGKTLGIIGL 153
Query: 530 GRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYITLHTPLIXST 709
G +G VA R AFGM I+ + A ++ ++EL ++ +D ++LH PL T
Sbjct: 154 GEIGTCVARRARAFGMRIV-YCARHEAPTASELQAERVELPELLRRSDVVSLHCPLTAET 212
Query: 710 RNFINA 727
+ + A
Sbjct: 213 KGMLGA 218
>UniRef50_Q1CG62 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=8; Yersinia|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase family
protein - Yersinia pestis (biovar Antiqua strain
Nepal516)
Length = 316
Score = 99.5 bits (237), Expect = 7e-20
Identities = 54/170 (31%), Positives = 88/170 (51%), Gaps = 2/170 (1%)
Frame = +2
Query: 221 LVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELT 400
+V+ + +T+ V+ A V+ R G GVDNID+ +A K+G+ + N P +
Sbjct: 47 VVLNNFAPMTERVMAAMPPGAVIVRYGVGVDNIDLSAARKRGMRICNVPDYGIEEVADHA 106
Query: 401 CTLMLVLARHVVPASTALKAGRW--DRALYTGSELAGKTLAILGLGRVGREVATRMYAFG 574
+ L LAR + +++GRW D+ + L T+ ++GLGR+ R ATRM FG
Sbjct: 107 AAMTLALARKLGRYEAGIRSGRWEIDQMVDGVRSLRDTTVGLIGLGRIARAYATRMAVFG 166
Query: 575 MNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYITLHTPLIXSTRNFIN 724
IIGFDP+V+ + + + + A ++LH PL TR+ I+
Sbjct: 167 CRIIGFDPYVTETEARSAGIEPLPQDKVIASAHILSLHVPLTPETRDLID 216
>UniRef50_Q1GAM7 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase; n=1; Lactobacillus delbrueckii subsp.
bulgaricus ATCC 11842|Rep: D-isomer specific
2-hydroxyacid dehydrogenase - Lactobacillus delbrueckii
subsp. bulgaricus (strain ATCC 11842 / DSM20081)
Length = 322
Score = 99.1 bits (236), Expect = 1e-19
Identities = 66/213 (30%), Positives = 106/213 (49%), Gaps = 4/213 (1%)
Frame = +2
Query: 98 LIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVK 277
++V G+ + L T A K+ L + + DAL+ V +E+LDAG K
Sbjct: 12 VLVAGLAVRQLPELEKVCEVTFAPAGAGKDWYLANLGDFDALIT-GKLPVDQELLDAGKK 70
Query: 278 LKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALK 457
LK+V G G D+IDVD A +G+ V N P + E+ TL+L L+R + + ++
Sbjct: 71 LKIVSATGVGYDHIDVDYASSQGIIVSNCPASVMQPTAEMAFTLLLALSRKLALYNQEMR 130
Query: 458 AGRW-DRALY--TGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPF-VSADQCAQ 625
+ D L G GKTL I G+GR+G+ +A+ FGMNI+ + + D+
Sbjct: 131 QENFLDTGLLENQGQSPVGKTLGIFGMGRIGKTLASYARTFGMNILYHNRHQLPEDEERA 190
Query: 626 FHCTKMELEDIWPLADYITLHTPLIXSTRNFIN 724
+ + L D+ ADY++L+ P T + I+
Sbjct: 191 LGVSYVPLADLLSQADYVSLNAPATAETYHVID 223
>UniRef50_Q0C254 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=2;
Alphaproteobacteria|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase family protein - Hyphomonas neptunium
(strain ATCC 15444)
Length = 337
Score = 99.1 bits (236), Expect = 1e-19
Identities = 56/184 (30%), Positives = 97/184 (52%)
Frame = +2
Query: 176 ISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGV 355
++ E++ + + VV A ++T+ V +A L V+ R G G + +DV++A G V
Sbjct: 44 LNVEDIRLLLEGAGGWVVGHA-RITRAVFEALPDLAVISRRGVGYEKVDVEAARDLGRVV 102
Query: 356 INAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGR 535
A G N S + +M+ + R A +A+KAG+W+ + G+EL + + I+G GR
Sbjct: 103 AIAAGGNDASVADQVIGMMISIGRRFQEAQSAMKAGKWN--ILVGTELYRRKVGIVGFGR 160
Query: 536 VGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYITLHTPLIXSTRN 715
+GR +A R+ F I+ P ++++ F + E + ADYI++H PL TR+
Sbjct: 161 IGRSLARRLSGFEAEILVCAPRLASEDIETFGLRHVAFETLLKEADYISVHAPLTPETRH 220
Query: 716 FINA 727
NA
Sbjct: 221 MFNA 224
>UniRef50_A6GGA6 Cluster: Probable 2-hydroxyacid dehydrogenase; n=1;
Plesiocystis pacifica SIR-1|Rep: Probable 2-hydroxyacid
dehydrogenase - Plesiocystis pacifica SIR-1
Length = 327
Score = 98.7 bits (235), Expect = 1e-19
Identities = 58/164 (35%), Positives = 88/164 (53%), Gaps = 3/164 (1%)
Frame = +2
Query: 245 VTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLA 424
V +LDA +L+VV G DN+DV + + + V N PG + +L L+L A
Sbjct: 63 VDAALLDAFPELRVVSNMAVGFDNVDVPACTARSIRVGNTPGVLTDATADLAMALLLSAA 122
Query: 425 RHVVPASTALKAGRWDR---ALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFD 595
R++ AS + GRW + G EL G TL ++GLG++G VA R AFGM+I+ +
Sbjct: 123 RNLPAASLDAREGRWQTWSPTGWLGLELRGATLGVVGLGKIGLAVAQRARAFGMDIL-YT 181
Query: 596 PFVSADQCAQFHCTKMELEDIWPLADYITLHTPLIXSTRNFINA 727
A + T++EL+ + AD ++LH PL TR+ I+A
Sbjct: 182 RRSDAPAPPELGATRVELDALLARADVVSLHVPLRPDTRHLIDA 225
>UniRef50_A0ZEB8 Cluster: Predicted dehydrogenase; n=6;
Cyanobacteria|Rep: Predicted dehydrogenase - Nodularia
spumigena CCY 9414
Length = 341
Score = 98.7 bits (235), Expect = 1e-19
Identities = 59/180 (32%), Positives = 95/180 (52%), Gaps = 3/180 (1%)
Frame = +2
Query: 179 SKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVI 358
+K E+ I + VR T++ + + KLKV+ +G G D ID+ A K GV V+
Sbjct: 46 TKNEINQAIQEASGVFVRYPTKLDAQAIGLAKKLKVISTSGFGTDAIDISVATKHGVVVV 105
Query: 359 NAPGANALSACELTCTLMLVLARHVVPASTALKAGRW-DRALYTGSELAGKTLAILGLGR 535
N PG + + E T ++L LA+ + + +K G + R +L GKTL I+GLGR
Sbjct: 106 NNPGLSTTAVAEHTICMILALAKKLTFLNQCVKTGNYLIRNQVQPMQLEGKTLGIVGLGR 165
Query: 536 VGREVATR-MYAFGMNIIGFDPFVSADQCAQFHCTKME-LEDIWPLADYITLHTPLIXST 709
+G VA++ AF M ++ +DP+V Q T +E L+ + +D+++LH L T
Sbjct: 166 IGSAVASKCSAAFQMRVLAYDPYVLPSQAEAVGGTLVENLDYLLAESDFVSLHPELTDET 225
>UniRef50_Q5FUD9 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Gluconobacter oxydans|Rep: D-3-phosphoglycerate
dehydrogenase - Gluconobacter oxydans (Gluconobacter
suboxydans)
Length = 314
Score = 98.3 bits (234), Expect = 2e-19
Identities = 64/200 (32%), Positives = 100/200 (50%), Gaps = 3/200 (1%)
Frame = +2
Query: 137 LNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDN 316
LN GI T + E ++ E+ + DA++ R + E LDA LK++ G+G +
Sbjct: 18 LNNAGIRTRYATAPTMEAVIREVGDADAVITRDLG-FSAEALDAAPNLKIISCHGSGTNR 76
Query: 317 IDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD-RALYTGS 493
I +A +GV V NAP N+ S E+T L+L + R + A A++ G W+ R G
Sbjct: 77 IAKAAAAARGVLVTNAPNTNSRSVAEMTIGLLLAVVRRLCEADLAVREGNWEFRYTGKGM 136
Query: 494 ELAGKTLAILGLGRVGREVA-TRMYAFGMNIIGFDPFVSADQCAQFHCTKM-ELEDIWPL 667
EL +TL ++G G + R VA GM ++ + P V AD + L+D+
Sbjct: 137 ELHTRTLGLVGFGAIARHVAQIAGQGLGMRVMAWSPSVPADVFEGAGVMRANSLDDLLVA 196
Query: 668 ADYITLHTPLIXSTRNFINA 727
+D ++LH P S R I+A
Sbjct: 197 SDVLSLHRPAQGSGRPTIDA 216
>UniRef50_Q9UYH9 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase; n=4; Thermococcaceae|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase - Pyrococcus abyssi
Length = 333
Score = 98.3 bits (234), Expect = 2e-19
Identities = 53/190 (27%), Positives = 98/190 (51%), Gaps = 6/190 (3%)
Frame = +2
Query: 179 SKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVI 358
S+EEL IP D +++ T++TK++L+ +LKV+ AG D++DV+ A K+G+ V
Sbjct: 32 SEEELKEIIPELDGIIIAPVTRITKDILERAERLKVISCQSAGYDHVDVEEATKRGIYVT 91
Query: 359 NAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSE------LAGKTLAI 520
G + + E L++ L R + A + ++ G+W+ + E L GK + I
Sbjct: 92 KVSGLLSEAVAEFALGLLISLMRKIHYADSFIREGKWESHTFVWREFKEVETLYGKEVGI 151
Query: 521 LGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYITLHTPLI 700
+G+G +G+ +A R+ FG I + D + + ++L+++ D + L PL
Sbjct: 152 VGMGAIGKAIARRLKPFGCEIYYWSRHRKEDIEREVNAKYLDLDELLEEVDIVILALPLT 211
Query: 701 XSTRNFINAD 730
T + IN +
Sbjct: 212 KETYHIINEE 221
>UniRef50_A7HBU0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=2; Anaeromyxobacter|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase
NAD-binding - Anaeromyxobacter sp. Fw109-5
Length = 313
Score = 97.9 bits (233), Expect = 2e-19
Identities = 59/208 (28%), Positives = 101/208 (48%), Gaps = 3/208 (1%)
Frame = +2
Query: 116 GAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGR 295
G + A L + + +E L+ E LV +V ++DA L+ V
Sbjct: 13 GGELAPLRELFEVRGGAPRPPPRERLVEEAREAAVLVPTYIDRVDAALVDALPALRHVAS 72
Query: 296 AGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW-- 469
G GV+++D+D+ ++GV V N PG + + L+L AR VV ++AG W
Sbjct: 73 YGVGVNHLDLDACRRRGVLVTNTPGVVTDATADHAMALLLAAARRVVEGDRVVRAGGWTE 132
Query: 470 -DRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKME 646
D A G+E+ GKT+ ++G GR+G+ A R F ++ + S ++
Sbjct: 133 VDPAWMLGTEVTGKTVGVVGFGRIGQAFARRARGFDTRVL----YTSPRDAGVAWAERVG 188
Query: 647 LEDIWPLADYITLHTPLIXSTRNFINAD 730
LE + AD+++LH PL+ +TRN ++ +
Sbjct: 189 LERLLAEADFVSLHVPLVPATRNLLSRE 216
>UniRef50_Q896Z8 Cluster: 2-hydroxyacid dehydrogenase; n=4;
Clostridium|Rep: 2-hydroxyacid dehydrogenase -
Clostridium tetani
Length = 357
Score = 97.5 bits (232), Expect = 3e-19
Identities = 55/182 (30%), Positives = 99/182 (54%)
Frame = +2
Query: 185 EELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINA 364
E L + D L++ + + KEV++A LK++ A G+D+I++++ K + V N+
Sbjct: 81 EVLKKRVETADVLILANMP-LKKEVIEAATNLKMISVAFTGIDHINMETCRKNNIMVCNS 139
Query: 365 PGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGR 544
G + S ELT L+L L R++VP + ++ G + Y+ +LAGKTL ++G G +G
Sbjct: 140 AGYSTSSVVELTFGLILSLLRNIVPLNDEVRNGNTKQG-YSQYDLAGKTLGVIGAGDIGT 198
Query: 545 EVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYITLHTPLIXSTRNFIN 724
EV AFG N++ ++ + T+ L+++ +D +TLH P T+ IN
Sbjct: 199 EVIRIGKAFGCNVLVYNR-SEKQHIKELGATQTTLDEVLKNSDIVTLHIPSNNETKGLIN 257
Query: 725 AD 730
++
Sbjct: 258 SE 259
>UniRef50_Q64UR3 Cluster: D-3-phosphoglycerate dehydrogenase; n=10;
cellular organisms|Rep: D-3-phosphoglycerate
dehydrogenase - Bacteroides fragilis
Length = 306
Score = 97.5 bits (232), Expect = 3e-19
Identities = 61/182 (33%), Positives = 96/182 (52%), Gaps = 1/182 (0%)
Frame = +2
Query: 182 KEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVIN 361
K +LL + + +A+++RS + EVLDA +LK+V RAGAG DN+D+++A GV V+N
Sbjct: 39 KAQLLDAVKDANAIIIRSDI-IDAEVLDAAKELKIVVRAGAGYDNVDLNAATAHGVCVMN 97
Query: 362 APGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVG 541
PG N+ + EL L++ R+ + +G+EL GK L I G VG
Sbjct: 98 TPGQNSNAVAELVFGLLVYAVRNFYNGT-------------SGTELMGKKLGIHAYGNVG 144
Query: 542 REVATRMYAFGMNIIGFDPFVSADQCAQFHCTKME-LEDIWPLADYITLHTPLIXSTRNF 718
R VA FGM + +D F D + ++ E+++ + ++LH P T+N
Sbjct: 145 RNVARIAKGFGMELYAYDAFCPKDVIEKDGVKAVDSAEELYKTCNIVSLHIPATAETKNS 204
Query: 719 IN 724
IN
Sbjct: 205 IN 206
>UniRef50_Q3A6W9 Cluster: 3-phosphoglycerate dehydrogenase; n=1;
Pelobacter carbinolicus DSM 2380|Rep: 3-phosphoglycerate
dehydrogenase - Pelobacter carbinolicus (strain DSM 2380
/ Gra Bd 1)
Length = 321
Score = 97.5 bits (232), Expect = 3e-19
Identities = 54/179 (30%), Positives = 90/179 (50%), Gaps = 3/179 (1%)
Frame = +2
Query: 203 IPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANAL 382
I + +AL+ RS +T ++ L+++ RAG+G+DN+D+D + ++ P A
Sbjct: 38 IRDREALIFRSGVNITAGIMACAPDLQLLIRAGSGLDNVDLDYLRNHDLKLVRIPQPGAR 97
Query: 383 SACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRM 562
+ EL +ML L+R ++ A L+ G W + G L K L I+GLG +G +
Sbjct: 98 AVAELAFGMMLALSRQILVADQLLRKGTWAKHQLRGHLLVNKQLGIVGLGNIGTLLGQMG 157
Query: 563 YAFGMNIIGFDPFVSADQCAQFHCTKMELED---IWPLADYITLHTPLIXSTRNFINAD 730
A+GM ++G S ++ AQF + L D + ADY+ + PL +T I D
Sbjct: 158 LAWGMQVLGCVEHPSPERAAQFEAKGLHLTDLNTVLSTADYLCVCVPLKTTTSGLIGHD 216
>UniRef50_P73990 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family; n=2; Cyanobacteria|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase family -
Synechocystis sp. (strain PCC 6803)
Length = 318
Score = 97.5 bits (232), Expect = 3e-19
Identities = 60/196 (30%), Positives = 100/196 (51%), Gaps = 3/196 (1%)
Frame = +2
Query: 152 IATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV--KLKVVGRAGAGVDNIDV 325
+A T ++S+ EL +I + D V+ T VL G KLK + + G GVD ID+
Sbjct: 31 VAPTITQQLSEAELCEQIADFDG-VIAGDDPFTARVLTIGKQGKLKALAKWGIGVDAIDL 89
Query: 326 DSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAG 505
+A + G+ N P ++ +++LAR + A++ G W + G L G
Sbjct: 90 AAAKQLGILTSNTPNVFGDEVADVAIGYLILLARELHCIDQAVRQGEWLKI--RGHSLRG 147
Query: 506 KTLAILGLGRVGREVATRMYAFGMNIIGFDPF-VSADQCAQFHCTKMELEDIWPLADYIT 682
KT I+G+G +G+ +A R+ + G+ ++G+DP +SAD C Q + L+D+ AD +
Sbjct: 148 KTAGIIGVGSIGQAIAVRLQSMGLKLLGYDPHPISADFCEQTGLHPVPLQDVLQQADCLF 207
Query: 683 LHTPLIXSTRNFINAD 730
L L + +NAD
Sbjct: 208 LACNLTPDNFHLLNAD 223
>UniRef50_A6UCB8 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=2; Sinorhizobium|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase
NAD-binding - Sinorhizobium medicae WSM419
Length = 310
Score = 97.5 bits (232), Expect = 3e-19
Identities = 54/163 (33%), Positives = 93/163 (57%), Gaps = 2/163 (1%)
Frame = +2
Query: 245 VTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLA 424
V+ +V+ A L+ + R G G+DN+ + ++G+G++ A GANA+ EL+ LML
Sbjct: 60 VSDKVIAAADSLRAISRNGTGIDNLPLPLLKERGIGILKAEGANAVGVAELSVGLMLAAL 119
Query: 425 RHVVPASTA-LKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPF 601
RH +PA TA ++AG W R+ G E+A +T+ I+G G +G+ VA + A ++I DPF
Sbjct: 120 RH-IPAETAGIRAGGWPRS--RGREIAERTVGIIGCGAIGKRVARAVSAMRASVIACDPF 176
Query: 602 -VSADQCAQFHCTKMELEDIWPLADYITLHTPLIXSTRNFINA 727
+ + F L++++ AD ++LH P + ++A
Sbjct: 177 RPNVEVYGPFKWA--SLDEVFAGADIVSLHCPAPADGKPIVDA 217
>UniRef50_A4S3N1 Cluster: Predicted protein; n=2; Ostreococcus|Rep:
Predicted protein - Ostreococcus lucimarinus CCE9901
Length = 380
Score = 97.5 bits (232), Expect = 3e-19
Identities = 62/194 (31%), Positives = 102/194 (52%), Gaps = 5/194 (2%)
Frame = +2
Query: 155 ATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDA----GVKLKVVGRAGAGVDNID 322
AT + A++S + + HDA+ V EV+DA GVKL ++ R AG DN+D
Sbjct: 61 ATYSSARLSLDTASLA-QGHDAVCVFVDDDARGEVVDALAERGVKL-ILLRC-AGFDNVD 117
Query: 323 VDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSELA 502
+ A ++G+ V+ P + LS E +M+ L RH+ + L+ G + GS +
Sbjct: 118 CERARERGISVLRVPAYDPLSISEHAVAMMMSLNRHLCASRDRLRMGNFTLDGLVGSSMR 177
Query: 503 GKTLAILGLGRVGREVATRM-YAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYI 679
GKT+ ++G G++GR VA + F M ++G+D F D C + + L+++ +D +
Sbjct: 178 GKTVGVVGTGKIGRGVAEILKNGFQMRVLGYDKFEKDDFCGDY----VSLDELLARSDVV 233
Query: 680 TLHTPLIXSTRNFI 721
+LH PL TR I
Sbjct: 234 SLHLPLTPETRGMI 247
>UniRef50_A3JX80 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding protein; n=1; Sagittula
stellata E-37|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding protein - Sagittula stellata
E-37
Length = 320
Score = 97.1 bits (231), Expect = 4e-19
Identities = 52/152 (34%), Positives = 80/152 (52%), Gaps = 1/152 (0%)
Frame = +2
Query: 152 IATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDS 331
I TT +IS++ I DAL++R+ +T +D +LK+V R G G D +DV +
Sbjct: 24 ITTTYIDEISEDSYTPHIAGADALLIRTQA-LTSPTIDRADRLKIVSRHGVGYDAVDVAA 82
Query: 332 AGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD-RALYTGSELAGK 508
+G+ + AN+ S E C L+L + + A A++ G W R ++ G+
Sbjct: 83 LNARGIALAVCGDANSTSVAEHACMLILAAFKRALRADVAVRRGPWGWRNQLESQDIRGR 142
Query: 509 TLAILGLGRVGREVATRMYAFGMNIIGFDPFV 604
L ILG GR+G+ AT M FGMNI DP++
Sbjct: 143 NLLILGFGRIGQHTATMMSGFGMNIRAHDPYL 174
>UniRef50_A2SRM1 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Methanocorpusculum
labreanum Z|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Methanocorpusculum
labreanum (strain ATCC 43576 / DSM 4855 / Z)
Length = 334
Score = 97.1 bits (231), Expect = 4e-19
Identities = 58/186 (31%), Positives = 98/186 (52%), Gaps = 3/186 (1%)
Frame = +2
Query: 176 ISKEELLMEIPNHDALVVRSATQVTKEVL-DAGVKLKVVGRAGAGVDN-IDVDSAGKKGV 349
+ ++E++ + DA + VT++++ A LKV+ G G +DV +A K +
Sbjct: 44 LKEDEIIEALAGVDAYIPGGEEVVTEKIIASAKNTLKVISFNGVGYGYYVDVPAAKKHNI 103
Query: 350 GVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGL 529
V N P AN+L+ E T L+L L + + + K+G W + Y +++ KT+ I+G+
Sbjct: 104 AVTNVPHANSLAVSEFTVALILTLMKKIPIMNKETKSGLWHK--YISQDVSDKTIGIVGM 161
Query: 530 GRVGREVATRM-YAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYITLHTPLIXS 706
G +GR VA +M Y FG I+ + +D + +EL D+ L+D ITLH P
Sbjct: 162 GSIGRLVAKKMYYGFGCKILYYSRTRESDIEQELDAKFVELHDLCRLSDVITLHLPYTSE 221
Query: 707 TRNFIN 724
TR+ I+
Sbjct: 222 TRHIID 227
>UniRef50_Q5FKH9 Cluster: Glyoxylate reductase; n=1; Lactobacillus
acidophilus|Rep: Glyoxylate reductase - Lactobacillus
acidophilus
Length = 321
Score = 96.7 bits (230), Expect = 5e-19
Identities = 59/188 (31%), Positives = 98/188 (52%), Gaps = 4/188 (2%)
Frame = +2
Query: 182 KEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVIN 361
++ +L I +D ++V KE++DA LKV+ G G D+ID+D A +KG+ V N
Sbjct: 39 RQWVLKNIAKYDGVIVAKMI-FDKEIIDAAKNLKVISTYGVGFDHIDIDYAREKGIVVTN 97
Query: 362 APGANALSACELTCTLMLVLARHVVPASTALKAGRW---DRALYTGSELAGKTLAILGLG 532
P + EL T+++ AR + AL+ G + D G + GKTL ILG+G
Sbjct: 98 CPNSVLRPTAELALTMIMASARRIRYYDHALREGVFLNVDEYDSQGYTIEGKTLGILGMG 157
Query: 533 RVGREVATRMYAFGMNIIGFDPF-VSADQCAQFHCTKMELEDIWPLADYITLHTPLIXST 709
R+G++VA A GM II + + + A+ + ++ + +D+++LH P T
Sbjct: 158 RIGQQVARFAKALGMKIIYHNRHQLKPELEAELNARYVDFASLVKNSDFLSLHAPATDET 217
Query: 710 RNFINADV 733
+ I+ DV
Sbjct: 218 YHIIDKDV 225
>UniRef50_Q30V14 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=3; Desulfovibrio|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase family
protein - Desulfovibrio desulfuricans (strain G20)
Length = 305
Score = 96.7 bits (230), Expect = 5e-19
Identities = 59/173 (34%), Positives = 92/173 (53%), Gaps = 1/173 (0%)
Frame = +2
Query: 215 DALVVRSATQ-VTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSAC 391
D + V + T+ +T V+DA LKV+ R G G+DN+D+++A +G+ V N P +
Sbjct: 48 DCVAVAAGTEPLTARVMDALPGLKVISRCGTGMDNVDMEAARARGIAVRNTPDGPTQAVA 107
Query: 392 ELTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAF 571
ELT L L L R V L++G W + + G+ L GK L I+G+GR+GR VA
Sbjct: 108 ELTLGLALDLMRQVSRMDRELRSGVWKKRM--GNLLGGKRLGIVGMGRIGRAVADIFTPL 165
Query: 572 GMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYITLHTPLIXSTRNFINAD 730
G+ + DP VS C + C M +E++ AD ++LH + + A+
Sbjct: 166 GVQVAFNDP-VSC--CGDYPC--MPVEELLGWADILSLHCSMTGGECSLFTAE 213
>UniRef50_Q0K073 Cluster: D-3-Phosphoglycerate dehydrogenase; n=2;
Burkholderiales|Rep: D-3-Phosphoglycerate dehydrogenase
- Ralstonia eutropha (strain ATCC 17699 / H16 / DSM 428
/ Stanier 337)(Cupriavidus necator (strain ATCC 17699 /
H16 / DSM 428 / Stanier337))
Length = 360
Score = 96.7 bits (230), Expect = 5e-19
Identities = 51/140 (36%), Positives = 77/140 (55%), Gaps = 1/140 (0%)
Frame = +2
Query: 278 LKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALK 457
L V +G+G D ID+D+ + GV V+N G NA S E+T LML + R + + +L+
Sbjct: 85 LLAVSSSGSGCDTIDIDACTEAGVAVLNQAGGNADSVAEMTLGLMLAVLRRIAESDRSLR 144
Query: 458 AGRWD-RALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHC 634
A + R G EL G+TL ++G+G GR VA A GM +IG DP + A + +
Sbjct: 145 AHNCESREDLMGHELRGRTLGLVGVGHAGRRVAALGRALGMRVIGCDPALDAAELSARGA 204
Query: 635 TKMELEDIWPLADYITLHTP 694
+ E++ AD ++LH P
Sbjct: 205 QAVSFEELLRSADIVSLHCP 224
>UniRef50_A4EQ78 Cluster: Dehydrogenase; n=1; Roseobacter sp.
SK209-2-6|Rep: Dehydrogenase - Roseobacter sp. SK209-2-6
Length = 343
Score = 96.7 bits (230), Expect = 5e-19
Identities = 55/199 (27%), Positives = 97/199 (48%), Gaps = 1/199 (0%)
Frame = +2
Query: 131 ELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGV 310
E+L A G A + KE L + A ++ ++ E + + +V+ R G GV
Sbjct: 31 EILEAAG-AEVVALQAKKETDLFDAARRCAAMMNQYARIGHETITRMQRCEVIARYGVGV 89
Query: 311 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD-RALYT 487
D +DV++A KG+ V N + L L LAR + A AG W ++
Sbjct: 90 DIVDVNAATAKGILVTNVQNYCTEEVADHAIALWLALARKLPDYDRATHAGLWQWQSGQP 149
Query: 488 GSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPL 667
L G+T+ ++ LG++G+ +A R AFG+N+I +DPF+ + A+ + ++
Sbjct: 150 VHRLRGRTMGVVSLGKIGQAIAARARAFGVNVIAYDPFLPGEAAAKLGVELVGKPELLAR 209
Query: 668 ADYITLHTPLIXSTRNFIN 724
+DYI + P+ T +F++
Sbjct: 210 SDYILMQAPMTPDTHHFLS 228
>UniRef50_UPI0000D9FBAD Cluster: PREDICTED: similar to
3-phosphoglycerate dehydrogenase, partial; n=1; Macaca
mulatta|Rep: PREDICTED: similar to 3-phosphoglycerate
dehydrogenase, partial - Macaca mulatta
Length = 333
Score = 96.3 bits (229), Expect = 7e-19
Identities = 69/214 (32%), Positives = 104/214 (48%), Gaps = 2/214 (0%)
Frame = +2
Query: 98 LIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVK 277
+ VDG+ C + +G K ++EEL + +A +VRS ++ +E +
Sbjct: 71 IAVDGIEKICKDNGLTFGKIEGYK---TQEELYSAAESAEACIVRS-DKLDEEFFNRAKN 126
Query: 278 LKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALK 457
LK+V RAGAGVD ID+D+A K V V N PG NA + E+ L++ + R+ A+
Sbjct: 127 LKIVVRAGAGVDTIDLDAASKHHVVVENTPGQNANAVAEMVFALLIAMKRNHFDAT---- 182
Query: 458 AGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCT 637
+G E+ G TL + G G V R + F M +DPF+S +Q + C
Sbjct: 183 ---------SGREIRGSTLGLYGCGNVSRAMIEVSKGFAMKCYSYDPFLSDEQIKE--CG 231
Query: 638 KMELEDIWPL--ADYITLHTPLIXSTRNFINADV 733
L D+ L D ++LH P T N IN D+
Sbjct: 232 AEPLHDLKELFKCDIVSLHVPATPQTINSINEDL 265
>UniRef50_A4RX85 Cluster: Predicted protein; n=3; Ostreococcus|Rep:
Predicted protein - Ostreococcus lucimarinus CCE9901
Length = 454
Score = 95.9 bits (228), Expect = 9e-19
Identities = 70/224 (31%), Positives = 111/224 (49%), Gaps = 22/224 (9%)
Frame = +2
Query: 122 KCAELLNAYGIATTTKAKISKEELLMEIPNHD-ALVVRSATQVTKEVLDAGVKLKVVGRA 298
K ++ G+ K K + E+P A+++RS EV ++ + R
Sbjct: 32 KTFNAISPVGLNKFPKGKYAVSGDDKELPGDPMAMMLRSHKLQVSEVPST---VRGIVRC 88
Query: 299 GAGVDNIDVDSAGKKGVGVINAPGANALSACELT-CTLMLVLA------RHVVPASTALK 457
GAG +NI V + G+ V N PGANA + EL C+L+L +HV +
Sbjct: 89 GAGTNNIPVKEMSELGIPVFNTPGANANAVKELVVCSLLLASRGIIEGNKHVNDVINVEE 148
Query: 458 AGRW---------DRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSA 610
G + D+A++ G+E+ GKTL ++GLG +G V GMN+IG+DP +S
Sbjct: 149 NGDYAKISVRIEKDKAMFGGTEIEGKTLGVIGLGAIGSRVVNAALGLGMNVIGYDPVLSL 208
Query: 611 DQCAQFHCTKM----ELEDIWPLADYITLHTPLIXS-TRNFINA 727
+ + KM +L++++ LADYIT+H P I T + I+A
Sbjct: 209 EAAWRLPGDKMSRADDLDELFALADYITIHVPYIKGVTHHLIDA 252
>UniRef50_O28495 Cluster: 2-hydroxyacid dehydrogenase, putative;
n=4; Archaea|Rep: 2-hydroxyacid dehydrogenase, putative
- Archaeoglobus fulgidus
Length = 323
Score = 95.9 bits (228), Expect = 9e-19
Identities = 56/162 (34%), Positives = 88/162 (54%), Gaps = 3/162 (1%)
Frame = +2
Query: 245 VTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLA 424
+T+E++ A K+K++ + G +NIDV++A K + V N G NALS E T L L
Sbjct: 60 ITEEMMRAMEKVKLIQQPSTGYNNIDVEAAKKLSITVANVGGVNALSVAEHTVMFALALL 119
Query: 425 RHVVPASTALKAGRWDR---ALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFD 595
R ++ A ++ +GRW++ A EL GKT I+G+G GREV R+ +G+ II D
Sbjct: 120 RRLIYAHNSVLSGRWEQDEMANLGVYELHGKTWGIIGMGAQGREVTKRLQGWGVKIIYHD 179
Query: 596 PFVSADQCAQFHCTKMELEDIWPLADYITLHTPLIXSTRNFI 721
A+ ++ + + + AD ++LH PL TR I
Sbjct: 180 -VRRAEDIEEYGVEFRDFDALLREADIVSLHVPLTEETRGMI 220
>UniRef50_Q0W672 Cluster: Glycerate dehydrogenase; n=2; Archaea|Rep:
Glycerate dehydrogenase - Uncultured methanogenic
archaeon RC-I
Length = 319
Score = 95.9 bits (228), Expect = 9e-19
Identities = 59/185 (31%), Positives = 94/185 (50%)
Frame = +2
Query: 176 ISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGV 355
+S EE L I D VV S ++ D+ LK+V G D++D+D+A KGV V
Sbjct: 34 LSMEEYLCRIAEADVAVV-SHFKLPARSFDSST-LKLVALTRTGYDDVDLDAATLKGVAV 91
Query: 356 INAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGR 535
NAPG + + E ++L R + A ++ ++D + G EL GKT+ I+G G+
Sbjct: 92 ANAPGYSNEAVAEHVFAMLLSFIRRISEADFWIREEKFDCTAFEGRELRGKTMGIIGTGQ 151
Query: 536 VGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYITLHTPLIXSTRN 715
+G VA FGM++I +D V + + L+ + +D+IT+H PL TR
Sbjct: 152 IGLRVAEIARCFGMDVIAYD--VRRNPAVAEKLRYVGLDRLCAESDFITVHLPLTSDTRG 209
Query: 716 FINAD 730
I+ +
Sbjct: 210 LIDEE 214
>UniRef50_Q89QF5 Cluster: Blr3173 protein; n=3; Bradyrhizobium|Rep:
Blr3173 protein - Bradyrhizobium japonicum
Length = 360
Score = 95.5 bits (227), Expect = 1e-18
Identities = 51/151 (33%), Positives = 87/151 (57%), Gaps = 2/151 (1%)
Frame = +2
Query: 278 LKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALK 457
L +V GAG D +DV++ GV V+N G NA S E +ML L++ ++ + L+
Sbjct: 90 LLLVSSNGAGFDPVDVEACTDAGVLVVNQSGGNAHSVAEHALAMMLTLSKRIIQSDRRLR 149
Query: 458 AGR-WDRALYTGSELAGKTLAILGLGRVGREVATRMYA-FGMNIIGFDPFVSADQCAQFH 631
R +R G+E+ KT+ I+GLG VGR +A GM ++ +DP+++A+ A+
Sbjct: 150 RERDVNRNDLVGNEVEHKTVGIIGLGNVGRRIAALCNGLLGMKVLAYDPYLTAEVMAERG 209
Query: 632 CTKMELEDIWPLADYITLHTPLIXSTRNFIN 724
K+EL+++ AD++++ PL +RN I+
Sbjct: 210 GEKVELDELLRRADFVSISCPLNKGSRNMIS 240
>UniRef50_A4SWE6 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=4; Bacteria|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase, NAD-binding -
Polynucleobacter sp. QLW-P1DMWA-1
Length = 326
Score = 95.5 bits (227), Expect = 1e-18
Identities = 53/188 (28%), Positives = 96/188 (51%), Gaps = 4/188 (2%)
Frame = +2
Query: 176 ISKEELLMEIPNHDALVVRSATQVTKEVLDA-GVKLKVVGRAGAGVDNIDVDSAGKKGVG 352
+++EEL+ + DA++ V E+LDA G + K++ G +N ++D+A K+GV
Sbjct: 35 LTREELMNAVKGRDAVITLLTDNVDAEILDAAGPQCKIIANYAVGFNNFNLDAATKRGVI 94
Query: 353 VINAPGANALSACELTCTLMLVLARHVVPASTALKAGR---WDRALYTGSELAGKTLAIL 523
+ N PG + L+L A+ + + ++ G+ W + G ++ GKTL I
Sbjct: 95 MTNTPGVLDKATATHAWALLLATAKRISESERYVREGKWKGWSPMTFIGQDVDGKTLGIA 154
Query: 524 GLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYITLHTPLIX 703
GLGR+G A + AF M +I + + D T ++ E + +D++++H PL
Sbjct: 155 GLGRIGTMFARKAAAFDMKVIYTNEQRNFDFEKDHGATFVDKETLLKESDFLSIHLPLTP 214
Query: 704 STRNFINA 727
T+ +I A
Sbjct: 215 ETKYYIGA 222
>UniRef50_Q7WEA3 Cluster: Phosphoglycerate dehydrogenase; n=1;
Bordetella bronchiseptica|Rep: Phosphoglycerate
dehydrogenase - Bordetella bronchiseptica (Alcaligenes
bronchisepticus)
Length = 329
Score = 95.1 bits (226), Expect = 2e-18
Identities = 67/205 (32%), Positives = 101/205 (49%), Gaps = 6/205 (2%)
Frame = +2
Query: 131 ELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGV 310
+LL A GI A + L I DA++VR Q+ E++D +L V+ G G
Sbjct: 16 QLLRAAGITVIEPAGPGLDALRQVIAGADAVLVRD--QLPAELIDMAPRLCVIANHGTGT 73
Query: 311 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW----DRA 478
D I V A G+ V+ P AN S E LMLV AR V A A + G W ++
Sbjct: 74 DKIAVAHADALGIPVVYTPQANVRSVAEHALMLMLVTARQAVQADAATRKGHWGFKYEQP 133
Query: 479 LYTGSELAGKTLAILGLGRVGREVATRMY-AFGMNIIGFDPFVSADQCAQFHCTKME-LE 652
+Y+ L GKTL ++GLGR GR + A M + + P + A + +++ L+
Sbjct: 134 MYS---LYGKTLGVIGLGRTGRLLCEMAAPALNMQALVWSPSLPAGEALPPGARRVDTLQ 190
Query: 653 DIWPLADYITLHTPLIXSTRNFINA 727
++ AD ++LH PL TR+ ++A
Sbjct: 191 ELLREADVVSLHRPLRPDTRHTLDA 215
>UniRef50_Q11JH0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Mesorhizobium sp.
BNC1|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Mesorhizobium sp. (strain BNC1)
Length = 342
Score = 95.1 bits (226), Expect = 2e-18
Identities = 55/169 (32%), Positives = 94/169 (55%), Gaps = 6/169 (3%)
Frame = +2
Query: 239 TQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLV 418
T +T+++L KL++V + G G+D ID++ A ++GV V G+NA + E T L+L
Sbjct: 60 TAITEKLLQESPKLRLVHKWGIGIDKIDLEGAERQGVYVAITAGSNAGAVAEHTIMLILA 119
Query: 419 LARHVVPASTALKAGRWDRALYTG-----SELAGKTLAILGLGRVGREVATRMYAFGMNI 583
R + A +++ G+W +YT +L+GKT+ ILG G +GR VA R+ F + I
Sbjct: 120 ALRRLALADQSMREGKW---IYTELRPLCRKLSGKTVGILGFGNIGRNVAQRLQGFDVEI 176
Query: 584 IGFDPFVSADQCA-QFHCTKMELEDIWPLADYITLHTPLIXSTRNFINA 727
I DPF + + + T + +++ ++ +TLH P + + INA
Sbjct: 177 IYHDPFRAPPEVEDRLKATYVSFDELIKRSNILTLHCPGGAANHHIINA 225
>UniRef50_A0JWH0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=14; Bacteria|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase, NAD-binding -
Arthrobacter sp. (strain FB24)
Length = 322
Score = 95.1 bits (226), Expect = 2e-18
Identities = 56/170 (32%), Positives = 93/170 (54%)
Frame = +2
Query: 221 LVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELT 400
+ +R T +E L LK++ G +ID+ +A + G+ V+ G + +A ELT
Sbjct: 53 IAMRERTAFGRERLAKLPDLKLLVTTGMANQSIDLRAAEELGI-VVCGTGGSPTAAPELT 111
Query: 401 CTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMN 580
L+L LAR + L+ GRW + G ELAGKTL +LGLG++GR VA AFGM+
Sbjct: 112 WGLLLALARSISFEDRNLREGRWQSTV--GFELAGKTLGVLGLGKIGRRVAAYGQAFGMD 169
Query: 581 IIGFDPFVSADQCAQFHCTKMELEDIWPLADYITLHTPLIXSTRNFINAD 730
+I + P ++ + AQ K+ E+++ +D +++H L +R + +
Sbjct: 170 VIAWSPNLTGEAAAQAGVRKVSKEELFRDSDVVSVHVRLSERSRGVVGEE 219
>UniRef50_Q6F7L0 Cluster: Glycerate dehydrogenase; n=3;
Gammaproteobacteria|Rep: Glycerate dehydrogenase -
Acinetobacter sp. (strain ADP1)
Length = 318
Score = 94.7 bits (225), Expect = 2e-18
Identities = 59/175 (33%), Positives = 93/175 (53%), Gaps = 6/175 (3%)
Frame = +2
Query: 221 LVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELT 400
+ + + + E L KLK++ + G +N+D+ +A +G+ V N G S + T
Sbjct: 48 VAITNKVVINAEALTRLPKLKLILVSATGTNNVDLRAAKAQGIVVCNCQGYGTASVAQHT 107
Query: 401 CTLMLVLARHVVPASTALKAGRWDRAL------YTGSELAGKTLAILGLGRVGREVATRM 562
TLML LA ++ A+ GRW +A Y EL+GKTL I+G G +G+EVA
Sbjct: 108 LTLMLALATSLLRYDHAVAQGRWQQASQFCFLDYPIIELSGKTLGIVGYGELGKEVARLA 167
Query: 563 YAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYITLHTPLIXSTRNFINA 727
AFGM I+ + Q + H ++ELE + P D+++LH PL T++ I+A
Sbjct: 168 QAFGMKIL----IANLPQRPK-HEDRLELEALLPQVDFLSLHCPLTEHTQHLIDA 217
>UniRef50_Q44NM9 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding; n=1;
Chlorobium limicola DSM 245|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, catalytic region:D- isomer
specific 2-hydroxyacid dehydrogenase, NAD-binding -
Chlorobium limicola DSM 245
Length = 305
Score = 94.7 bits (225), Expect = 2e-18
Identities = 51/185 (27%), Positives = 93/185 (50%)
Frame = +2
Query: 140 NAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNI 319
N Y + + E+ ++EI +V + ++V+D L+ + R G G+D++
Sbjct: 25 NGYEVINNPFGRKLTEDEVIEIAKECVGIVAGVEPLNQKVMDNLPNLRCISRVGVGMDSV 84
Query: 320 DVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSEL 499
D+D A +KG+ V N P S ELT + L L R V A +K G W + + G+ +
Sbjct: 85 DLDYAKQKGIVVTNTPDGPTRSVAELTIAMTLALLRKVPQAHMNIKQGVWKKEI--GNLM 142
Query: 500 AGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYI 679
K + ++GLG++G+ A++ AFG +++ FD + +++E + +D I
Sbjct: 143 YEKKVGLIGLGKIGKLAASQFQAFGCSVMAFDLYPETAWAEANDVEIVDMEKLLAESDII 202
Query: 680 TLHTP 694
+LH P
Sbjct: 203 SLHIP 207
>UniRef50_Q8TR50 Cluster: Glycerate dehydrogenase; n=2;
Methanosarcina|Rep: Glycerate dehydrogenase -
Methanosarcina acetivorans
Length = 319
Score = 94.7 bits (225), Expect = 2e-18
Identities = 56/184 (30%), Positives = 89/184 (48%)
Frame = +2
Query: 176 ISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGV 355
+S +E + I + D +VV V+ E L + +LK++ G DN+D++ A GV V
Sbjct: 33 VSLDEFIDRIKDADIVVV-GRYGVSAEALRSAPRLKMISLWQTGFDNVDLEEATDHGVIV 91
Query: 356 INAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGR 535
N P S E L L L R V A L+ G +D Y G++L KT+ +LG G
Sbjct: 92 SNVPSYAFESVAEFVFALTLNLLRRVHLADMNLREGLFDWKYYVGNQLMSKTIGVLGTGE 151
Query: 536 VGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYITLHTPLIXSTRN 715
+G+ V + F MN++ S ++ ++L+ + +D +TLH PL T +
Sbjct: 152 IGKRVIQIAHGFNMNVLSVTAHPSPERAKALGVKFVDLDTLLSESDIVTLHVPLTPETEH 211
Query: 716 FINA 727
I A
Sbjct: 212 MIGA 215
>UniRef50_A4TF35 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Mycobacterium gilvum
PYR-GCK|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Mycobacterium gilvum
PYR-GCK
Length = 298
Score = 94.3 bits (224), Expect = 3e-18
Identities = 57/188 (30%), Positives = 92/188 (48%)
Frame = +2
Query: 167 KAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKG 346
+ + S ELL E + ++ ++ + KLK V R G G+D++D ++A + G
Sbjct: 27 RQQFSSSELL-EYSSRLIGIIAGDDELDADFFAGAGKLKTVIRWGIGMDSVDHEAARRHG 85
Query: 347 VGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILG 526
V V N PG + +L LAR + A++ G W + G L G L I+G
Sbjct: 86 VTVRNTPGVFGYEVADSAFGYILNLARGYMAVDAAVRRGEWPKV--EGITLDGSRLGIVG 143
Query: 527 LGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYITLHTPLIXS 706
G +GRE+A R FG ++ FDPFV A + +EL+++ + ++ L PL
Sbjct: 144 FGAIGREIAKRGAGFGQEVVAFDPFVKASPAG---VSMVELDELLATSRFVVLACPLTPE 200
Query: 707 TRNFINAD 730
T + I+AD
Sbjct: 201 TFHLIDAD 208
>UniRef50_A4EAR0 Cluster: Putative uncharacterized protein; n=1;
Collinsella aerofaciens ATCC 25986|Rep: Putative
uncharacterized protein - Collinsella aerofaciens ATCC
25986
Length = 387
Score = 94.3 bits (224), Expect = 3e-18
Identities = 60/185 (32%), Positives = 96/185 (51%), Gaps = 13/185 (7%)
Frame = +2
Query: 215 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 394
DA+++RS T + L G++ + R GAGV+NI V+ KKGV V N+PGAN+ + E
Sbjct: 32 DAILMRS-TDLHGYELPEGIR--AIARCGAGVNNIPVEEYAKKGVVVFNSPGANSNAVKE 88
Query: 395 LTCTLMLVLARHVVPASTALKAGRWD----------RALYTGSELAGKTLAILGLGRVGR 544
L ++++ +R VV + ++ D + + G EL GK + ++GLG VG
Sbjct: 89 LVLGMLVLSSRGVVQSMNWVRDNADDPEIQVDAEKAKKAFVGRELKGKRIGVIGLGNVGS 148
Query: 545 EVATRMYAFGMNIIGFDPFVSADQCAQFHCTKME---LEDIWPLADYITLHTPLIXSTRN 715
+VA GM++ G+DPF+S + LED+ DY+T+H P T
Sbjct: 149 KVANACVDLGMDVYGYDPFISVEHAWVLSREVQRVGTLEDLCRGCDYLTVHVPSKADTIG 208
Query: 716 FINAD 730
I+ +
Sbjct: 209 MISTE 213
>UniRef50_A1W7V5 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=2; Proteobacteria|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Acidovorax sp. (strain JS42)
Length = 337
Score = 94.3 bits (224), Expect = 3e-18
Identities = 50/161 (31%), Positives = 79/161 (49%)
Frame = +2
Query: 239 TQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLV 418
+++T EVL +L+++ G D+ID+D G+ V N P + E L+L
Sbjct: 52 SRLTAEVLAQFPRLRLIATRSTGYDHIDLDYCRAHGIAVSNVPDYGDATVAEHAFALLLA 111
Query: 419 LARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDP 598
++RH+V + + G + + G EL GKTL +LG GR+GR V FGM I+ +D
Sbjct: 112 VSRHIVTGAERTRRGDFSQHGLRGFELRGKTLGVLGTGRIGRRVIEIGKGFGMKIVAYDL 171
Query: 599 FVSADQCAQFHCTKMELEDIWPLADYITLHTPLIXSTRNFI 721
F A ++L + AD +TLH P T + +
Sbjct: 172 FPDAAVAEHLGYEYLDLHVLLSQADVVTLHVPATPQTHHLL 212
>UniRef50_Q0CUD5 Cluster: Putative uncharacterized protein; n=1;
Aspergillus terreus NIH2624|Rep: Putative uncharacterized
protein - Aspergillus terreus (strain NIH 2624)
Length = 743
Score = 94.3 bits (224), Expect = 3e-18
Identities = 56/177 (31%), Positives = 93/177 (52%), Gaps = 3/177 (1%)
Frame = +2
Query: 209 NHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSA 388
N AL++RS+ +T E + + L +G+ G G++ ID D+ K+G+ ++N PGANA
Sbjct: 476 NARALLIRSS-YLTAEDIASCPNLVAIGKHGVGIEKIDQDACVKRGIKILNTPGANARDV 534
Query: 389 CELTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMY- 565
EL TL L +AR + +T + + G L KT+ I+G+G +GR VA
Sbjct: 535 AELVVTLALSVARGIRSITTRQMSKPVPKETCNGLTLYQKTIGIIGMGNIGRTVAEIFRG 594
Query: 566 AFGMNIIGFDPFVSADQCAQF--HCTKMELEDIWPLADYITLHTPLIXSTRNFINAD 730
F +I+ +D + + D Q H ++++ AD +++H PL TR+ I D
Sbjct: 595 GFAADIVAYDAY-TPDNIWQHIPHVRARSIDEVLVRADVLSIHVPLTKDTRDMITYD 650
>UniRef50_A4U158 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding; n=4;
Proteobacteria|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding -
Magnetospirillum gryphiswaldense
Length = 319
Score = 93.9 bits (223), Expect = 4e-18
Identities = 61/200 (30%), Positives = 99/200 (49%), Gaps = 2/200 (1%)
Frame = +2
Query: 131 ELLNAYGIAT--TTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGA 304
EL YG T T A +S E L+ + HD + + ++ +VL +L+VVG+ G
Sbjct: 25 ELTQRYGQVTFNETGASLSGESLVAFLDGHDKAIT-ALERLNGDVLARLPRLRVVGKYGV 83
Query: 305 GVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALY 484
G+D ID+ + G + G N S EL + L RHV A+ ++ G W + +
Sbjct: 84 GLDMIDLPAMSALGKKLGWTGGVNRRSVSELVIAATISLLRHVPAANQLVRDGGWRQLM- 142
Query: 485 TGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWP 664
G +L+ + + I+G G +G+++A + AFG ++ D D A M L+ +
Sbjct: 143 -GRQLSQRVVGIVGCGHIGKDLAVLLRAFGCRVLAHDIKAFPDFYAAHGVEPMGLDALLQ 201
Query: 665 LADYITLHTPLIXSTRNFIN 724
AD +TLH P STRN ++
Sbjct: 202 QADVVTLHLPGDESTRNILD 221
>UniRef50_UPI00015B49ED Cluster: PREDICTED: similar to putative
glyoxylate reductase/hydroxypyruvate reductase; n=1;
Nasonia vitripennis|Rep: PREDICTED: similar to putative
glyoxylate reductase/hydroxypyruvate reductase - Nasonia
vitripennis
Length = 699
Score = 93.5 bits (222), Expect = 5e-18
Identities = 51/189 (26%), Positives = 96/189 (50%), Gaps = 4/189 (2%)
Frame = +2
Query: 176 ISKEELLMEIPNHDALVVRSATQVTKEVLDA-GVKLKVVGRAGAGVDNIDVDSAGKKGVG 352
I K EL+ I DA+ ++ +EVL A G KLKV+ GVD++D+ + + +
Sbjct: 410 IPKPELIKRIKEADAIFCLLTDKIDEEVLSAAGSKLKVIATMSVGVDHLDLKAIKSRNIP 469
Query: 353 VINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDR---ALYTGSELAGKTLAIL 523
+ PG + ELT L+L +R ++ A+ A+ G W TG +++G + I+
Sbjct: 470 IGYTPGVLTDATAELTMALLLATSRRLIEANRAIYRGEWKAWCPTWMTGPKISGSNIGIV 529
Query: 524 GLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYITLHTPLIX 703
GLGR+G V+ + +FG+ I + + K++L+++ +D++ + T L+
Sbjct: 530 GLGRIGLRVSEYLKSFGVAKILYTSRTEKPAATKLGAQKVDLDELLKESDFVIVTTALVP 589
Query: 704 STRNFINAD 730
T++ +
Sbjct: 590 ETKHLFKKE 598
>UniRef50_Q8CPW2 Cluster: Glycerate dehydrogenase; n=4;
Staphylococcus|Rep: Glycerate dehydrogenase -
Staphylococcus epidermidis (strain ATCC 12228)
Length = 323
Score = 93.5 bits (222), Expect = 5e-18
Identities = 54/187 (28%), Positives = 91/187 (48%), Gaps = 3/187 (1%)
Frame = +2
Query: 176 ISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGV 355
+S+E L + + A V+ + + +EV +LKV+ G DNID+ A K GV V
Sbjct: 34 MSRESFLANVEDATACVITLSEHIDEEVFLRAQQLKVIANMAVGFDNIDISLAKKHGVVV 93
Query: 356 INAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDR---ALYTGSELAGKTLAILG 526
N P + EL TLML +AR ++ A++ ++ G+W L +G ++ G T+ I G
Sbjct: 94 TNTPHVLTETTAELGFTLMLTVARRIIEATSYIQEGKWKSWGPYLLSGKDVYGATVGIFG 153
Query: 527 LGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYITLHTPLIXS 706
+G +G+ A R+ F II + + + T + + + +D+I PL
Sbjct: 154 MGDIGKAFARRLQGFDARIIYHNRKRDLNAERDLNATYVTFKSLLEQSDFIICTAPLTKE 213
Query: 707 TRNFINA 727
T N +A
Sbjct: 214 TENQFDA 220
>UniRef50_Q49UN3 Cluster: NAD-dependent formate dehydrogenase; n=13;
Staphylococcus|Rep: NAD-dependent formate dehydrogenase
- Staphylococcus saprophyticus subsp. saprophyticus
(strain ATCC 15305 /DSM 20229)
Length = 389
Score = 93.5 bits (222), Expect = 5e-18
Identities = 52/165 (31%), Positives = 84/165 (50%), Gaps = 2/165 (1%)
Frame = +2
Query: 245 VTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLA 424
+TKE ++ LK+V AG G D++D+ +A + +GV+ G+N +S E +L+L
Sbjct: 116 MTKERIEKAPNLKLVITAGVGSDHVDLQAASEHNIGVVEVTGSNTISVAEHAVMDLLILL 175
Query: 425 RHVVPASTALKAGRWDRALYTG--SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDP 598
R+ K G W+ + EL KT+ I G GR+G+ VA R+ F + I +DP
Sbjct: 176 RNYEEGHRQAKDGEWNLSKVGNHVHELQIKTIGIFGFGRIGQLVAERLAPFNVTIQHYDP 235
Query: 599 FVSADQCAQFHCTKMELEDIWPLADYITLHTPLIXSTRNFINADV 733
D H T + +++ +D +T+H PL T N + DV
Sbjct: 236 INQKD---NEHSTFVNFDELVSTSDAVTIHAPLTPETDNLFDYDV 277
>UniRef50_Q03WU1 Cluster: Lactate dehydrogenase related
dehydrogenase; n=1; Leuconostoc mesenteroides subsp.
mesenteroides ATCC 8293|Rep: Lactate dehydrogenase
related dehydrogenase - Leuconostoc mesenteroides subsp.
mesenteroides (strain ATCC 8293 /NCDO 523)
Length = 312
Score = 93.1 bits (221), Expect = 6e-18
Identities = 54/182 (29%), Positives = 93/182 (51%), Gaps = 2/182 (1%)
Frame = +2
Query: 185 EELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINA 364
E+ L+ + + A+++ + K DA LK++ R G G DNI V+SA K GV V N
Sbjct: 35 EKKLLSLASDAAVIIMTDMAFDKNWFDALPNLKLIARRGVGYDNIPVESATKHGVWVTNT 94
Query: 365 PGANALSACELTCTLMLVLARHVVPASTALKAGR--WDRALYTGSELAGKTLAILGLGRV 538
PGANA++ EL TL+L + R V A+ +++ G A G L+GK + ++G G++
Sbjct: 95 PGANAIAVAELAVTLILTVLRKVNQATNSVQKGEALTYPASLMGHNLSGKIIGLIGYGQI 154
Query: 539 GREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYITLHTPLIXSTRNF 718
+ + ++ FG +++ + QF + + + +D I+LH P T
Sbjct: 155 AQNLEKILHGFGAHVLVYSRTKRETLYGQF----VSYDTLLAQSDIISLHIPATPETSGI 210
Query: 719 IN 724
+N
Sbjct: 211 LN 212
>UniRef50_Q12VM6 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=2; cellular organisms|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Methanococcoides burtonii (strain DSM
6242)
Length = 317
Score = 93.1 bits (221), Expect = 6e-18
Identities = 53/190 (27%), Positives = 96/190 (50%)
Frame = +2
Query: 152 IATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDS 331
I + + KI+ EL +I N D L+ ++T+EV+ LK++ R G G+D ++ +
Sbjct: 29 ILNSHERKITTRELASDIGNSDVLIA-GTERITEEVIKNAPNLKLISRVGVGLDGVNFEL 87
Query: 332 AGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKT 511
K G+ V P A ++ EL ++L L+R + ++ G WDR Y G+ L GKT
Sbjct: 88 CNKYGIKVTYTPDAPTMAVAELCVGIILDLSRKISYTDRNVRKGVWDR--YMGNLLYGKT 145
Query: 512 LAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYITLHT 691
+ I G+GR+G+ + + +F + + D ++ + D+ +D I+++
Sbjct: 146 VGIFGMGRIGKSLVHLLSSFNVKFLVNDITPDFSFGRLYNIEFVSKNDVLEKSDIISINI 205
Query: 692 PLIXSTRNFI 721
PL T +FI
Sbjct: 206 PLKKDTYDFI 215
>UniRef50_UPI000050F9E4 Cluster: COG0111: Phosphoglycerate
dehydrogenase and related dehydrogenases; n=1;
Brevibacterium linens BL2|Rep: COG0111: Phosphoglycerate
dehydrogenase and related dehydrogenases -
Brevibacterium linens BL2
Length = 314
Score = 92.7 bits (220), Expect = 8e-18
Identities = 49/155 (31%), Positives = 80/155 (51%)
Frame = +2
Query: 227 VRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCT 406
+ ++ V +++L LKV+ RAG G DN+D+D+A + G+ V N PG N + EL
Sbjct: 54 IAASEPVARDMLATSPMLKVIARAGVGYDNVDIDAAAELGIRVCNTPGVNHHAVAELALA 113
Query: 407 LMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNII 586
LML AR + + G W R G+EL GK+L ++G G G+ +A A GM ++
Sbjct: 114 LMLACARRLNTVLAGVDDGGWPRE--AGTELRGKSLGVIGYGPSGKAIAALGVALGMRVL 171
Query: 587 GFDPFVSADQCAQFHCTKMELEDIWPLADYITLHT 691
++Q + + + ADY++LH+
Sbjct: 172 VSTAHPDSEQSSGIEFA--DFDTTIKAADYLSLHS 204
>UniRef50_Q74CK1 Cluster: Glycerate dehydrogenase; n=12;
Bacteria|Rep: Glycerate dehydrogenase - Geobacter
sulfurreducens
Length = 327
Score = 92.7 bits (220), Expect = 8e-18
Identities = 60/186 (32%), Positives = 96/186 (51%), Gaps = 6/186 (3%)
Frame = +2
Query: 188 ELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAP 367
EL +E +V+ S ++ + L A KL+ + G +N+DV++AGK+G+ V N P
Sbjct: 40 ELRVERAKDADIVLTSKVKLDEATLAALPKLRYISMLATGYNNVDVEAAGKRGIPVANIP 99
Query: 368 GANALSACELTCTLMLVLARHVVPASTALKAGRW----DRALYTGS--ELAGKTLAILGL 529
+ S + T L+L LA HV +A+KA W D + + EL G TL I+G
Sbjct: 100 AYSTESVVQTTFALLLELAVHVGIHDSAVKAREWVRSPDHSFWKTPIVELDGLTLGIVGY 159
Query: 530 GRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYITLHTPLIXST 709
G +GR VA AFGM I+ + P V AD + L++++ +D ++L+ P
Sbjct: 160 GTIGRAVARVGAAFGMKIMAYAPRVPAD-LGPVPVRFVSLDELFAGSDVVSLNCPQTAEN 218
Query: 710 RNFINA 727
F+N+
Sbjct: 219 TGFVNS 224
>UniRef50_Q3Y1E6 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, catalytic region:D- isomer specific
2-hydroxyacid dehydrogenase, NAD-binding; n=1;
Enterococcus faecium DO|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, catalytic region:D- isomer
specific 2-hydroxyacid dehydrogenase, NAD-binding -
Enterococcus faecium DO
Length = 386
Score = 92.7 bits (220), Expect = 8e-18
Identities = 59/179 (32%), Positives = 94/179 (52%), Gaps = 9/179 (5%)
Frame = +2
Query: 215 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 394
+ +V+RS T+V E L L + RAG GV+ I+V+ A + G V+N PG NA + E
Sbjct: 32 EGIVIRS-TKVKDEWLTPD--LLAISRAGVGVNTINVEKASENGTIVMNTPGVNANAVKE 88
Query: 395 LTCTLMLVLARHVVPAS---------TALKAGRWDRALYTGSELAGKTLAILGLGRVGRE 547
L +L+ +R ++ AS L+ R+ Y G EL GKT+ +LGLG +G +
Sbjct: 89 LVLCCLLLSSRPIIEASRMVQTLTGPNILEQAENKRSAYVGRELQGKTIGLLGLGAIGTK 148
Query: 548 VATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYITLHTPLIXSTRNFIN 724
VA Y+ GM+++G+ S + + +LE + +DYI + PL T+ I+
Sbjct: 149 VALSCYSLGMDVLGY----SIRDAQLDYVRQADLETVLSTSDYIVVMLPLTEDTKGLID 203
>UniRef50_Q5KQ73 Cluster: D-3-phosphoglycerate dehydrogenase,
putative; n=3; Filobasidiella neoformans|Rep:
D-3-phosphoglycerate dehydrogenase, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 594
Score = 92.7 bits (220), Expect = 8e-18
Identities = 60/164 (36%), Positives = 88/164 (53%), Gaps = 11/164 (6%)
Frame = +2
Query: 269 GVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPAST 448
G KLK + + G GVD ID+ +A K G+ V+N PG NA + EL +ML LAR
Sbjct: 96 GGKLKYISKQGTGVDKIDIVNAKKLGIPVMNTPGVNAQAVAELAFGMMLSLARQTPSIDR 155
Query: 449 ALKAGRWDRAL--YTGSELAGKTLAILGLGRVGREVATRMY--AFGMNIIGFDPFV---- 604
++ G L + G L GKTL ++G G +G VA +M+ AF I+ +DP++
Sbjct: 156 KIRKGASVTKLDGWKGQMLYGKTLGVIGGGNIGLLVA-KMFAGAFSGKIVLYDPYLKSLD 214
Query: 605 ---SADQCAQFHCTKMELEDIWPLADYITLHTPLIXSTRNFINA 727
SA A H E++++ +D +T+H PL ST N I+A
Sbjct: 215 TWHSAIPNASIHKVS-EIDELLTTSDIVTIHVPLTPSTENMISA 257
>UniRef50_UPI000023EBBC Cluster: hypothetical protein FG00146.1; n=1;
Gibberella zeae PH-1|Rep: hypothetical protein FG00146.1
- Gibberella zeae PH-1
Length = 1068
Score = 91.9 bits (218), Expect = 1e-17
Identities = 57/181 (31%), Positives = 100/181 (55%), Gaps = 7/181 (3%)
Frame = +2
Query: 206 PNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALS 385
P+ A++++ +T++ L + +L+V+G+ G G+D IDV++ + V V N PG NA +
Sbjct: 790 PHATAILIKDY-YITEDDLASAPQLRVIGKQGVGLDKIDVEACKRHNVKVCNTPGVNASA 848
Query: 386 ACELTCTLMLVLARHV--VPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATR 559
E+T L L +AR V V ++ + G L+ K + ++G+G +G+ +A +
Sbjct: 849 VAEMTLCLALTVAREVPDVVIRQKIQGEAIRKETVAGMLLSRKIIGVVGMGHIGQAIA-Q 907
Query: 560 MYAFGM--NIIGFDPFVSADQ--CAQFHCTKME-LEDIWPLADYITLHTPLIXSTRNFIN 724
M+ G+ II FDP+ +Q ++E L ++ +AD +TLH PL ST+N I
Sbjct: 908 MFVGGLQAEIIAFDPYFHDNQGPWDTIPYKRVETLTELLEVADVVTLHVPLTHSTKNMIA 967
Query: 725 A 727
A
Sbjct: 968 A 968
>UniRef50_Q120S8 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=2; Proteobacteria|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Polaromonas sp. (strain JS666 / ATCC
BAA-500)
Length = 325
Score = 91.9 bits (218), Expect = 1e-17
Identities = 58/185 (31%), Positives = 92/185 (49%), Gaps = 2/185 (1%)
Frame = +2
Query: 179 SKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVI 358
S+E ++ + D ++VR ++ V++ V+DA + K V R G GVDNID+ +A + + V
Sbjct: 45 SEEAAILAVRGADVVLVRESS-VSRRVIDAMDRCKAVIRYGIGVDNIDMAAAAARRIAVA 103
Query: 359 NAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGS-ELAGKTLAILGLGR 535
N P T L L + R VV +++GRW + L G+TL ++G GR
Sbjct: 104 NVPDYGTDEVSTQTVALALAVVRQVVSHDREVRSGRWSTGVIKPMYRLRGRTLGLIGYGR 163
Query: 536 VGREVATRMYAFGM-NIIGFDPFVSADQCAQFHCTKMELEDIWPLADYITLHTPLIXSTR 712
+ R + FG ++ DP Q +++DI AD I+LH PL TR
Sbjct: 164 IARMTHEKFSGFGFGRVLVNDPCPELPDGVQ----AADVDDICREADIISLHAPLTAQTR 219
Query: 713 NFINA 727
+ I+A
Sbjct: 220 HIIDA 224
>UniRef50_A3IA61 Cluster: D-3 phosphoglycerate dehydrogenase; n=1;
Bacillus sp. B14905|Rep: D-3 phosphoglycerate
dehydrogenase - Bacillus sp. B14905
Length = 319
Score = 91.9 bits (218), Expect = 1e-17
Identities = 59/212 (27%), Positives = 99/212 (46%), Gaps = 2/212 (0%)
Frame = +2
Query: 101 IVDGVGAKCAELLNAYG--IATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 274
+ D + K AE + G + + EL D +++ + T EV+D
Sbjct: 11 VSDSIIEKLAEPIKQAGHEFVYYNEKTTDRAELARRSEGADVIMIANNPYPT-EVIDQNA 69
Query: 275 KLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL 454
LK++ A GVD++ + A + V V NA G + ELT L+L + RH+ +
Sbjct: 70 NLKLINVAFTGVDHVGIGQARNQDVMVCNAAGYANQAVAELTIGLVLDVYRHITQGDKEI 129
Query: 455 KAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHC 634
A + A + GSE+ GKT+ ++G G++G A AFG I+ D
Sbjct: 130 HADHFPGA-FQGSEIKGKTVGLIGTGKIGMMTARLFKAFGAKIVASDQSRRNPAAEVLGI 188
Query: 635 TKMELEDIWPLADYITLHTPLIXSTRNFINAD 730
MEL+++ +D ++LH PL+ ST+ I+ +
Sbjct: 189 EYMELDELLAQSDIVSLHIPLLSSTKGLISKE 220
>UniRef50_A0AFI6 Cluster: Complete genome; n=1; Listeria welshimeri
serovar 6b str. SLCC5334|Rep: Complete genome - Listeria
welshimeri serovar 6b (strain ATCC 35897 / DSM 20650
/SLCC5334)
Length = 349
Score = 91.9 bits (218), Expect = 1e-17
Identities = 53/178 (29%), Positives = 97/178 (54%), Gaps = 5/178 (2%)
Frame = +2
Query: 215 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 394
D L+V A V+K+++ + KL+++G + G++N+ V++A ++ + VI+ NA +
Sbjct: 74 DILLVHIAP-VSKKMIASAKKLRLIGASRGGMENVAVEAATERKIPVIHVI-RNAEPVAD 131
Query: 395 LTCTLMLVLARHVVPASTALKAGRWDRALYTGS---ELAGKTLAILGLGRVGREVATRMY 565
T LM R++ A ++K GRWD+ + LA T+ ++GLG +G+ VA R+
Sbjct: 132 FTVALMYAETRNIARAHLSIKNGRWDKGFSNDAYKTTLAKHTVGLIGLGYIGKLVAKRLN 191
Query: 566 AFGMNIIGFDPFVSADQCAQ--FHCTKMELEDIWPLADYITLHTPLIXSTRNFINADV 733
G+ +I +DPF+ + L +++ AD I+LH + T N INA++
Sbjct: 192 GLGVKVIAYDPFIDPKKLVDEGLDIELKGLHEVFREADIISLHMRVTKETTNMINAEL 249
>UniRef50_Q8ZXX8 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Pyrobaculum aerophilum|Rep: D-3-phosphoglycerate
dehydrogenase - Pyrobaculum aerophilum
Length = 323
Score = 91.9 bits (218), Expect = 1e-17
Identities = 59/187 (31%), Positives = 91/187 (48%), Gaps = 2/187 (1%)
Frame = +2
Query: 176 ISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGV 355
+ KE L+ +ALV+ + KEVLDAG KLK+V A GVD+IDV+ A +KGV V
Sbjct: 40 VPKEVLIDAARRCEALVIFIGDVIDKEVLDAGEKLKIVSTASVGVDHIDVEYAKRKGVVV 99
Query: 356 INAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDR--ALYTGSELAGKTLAILGL 529
+ P + +L L++ + R + +++G D G L GK I+GL
Sbjct: 100 AHTPYVLVDAVADLAVGLLIAVTRKIALGDRLIRSGAADAVWGSLMGVNLRGKRAGIVGL 159
Query: 530 GRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYITLHTPLIXST 709
G +G +A R+ AF + + + + MEL+ + +D+I L L T
Sbjct: 160 GNIGVAIARRLKAFDIEVAYWSRRRKPEVEFALGIEYMELDSLLSSSDFIFLTMALTPET 219
Query: 710 RNFINAD 730
R F N +
Sbjct: 220 RWFFNRE 226
>UniRef50_Q8YK31 Cluster: Glycerate dehydrogenase; n=3;
Cyanobacteria|Rep: Glycerate dehydrogenase - Anabaena
sp. (strain PCC 7120)
Length = 332
Score = 91.5 bits (217), Expect = 2e-17
Identities = 60/217 (27%), Positives = 111/217 (51%), Gaps = 5/217 (2%)
Frame = +2
Query: 95 VLIVDGVGAKCAELL--NAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDA 268
V+I + V + ELL + IA +K +S+EE+L + +AL+V + + L
Sbjct: 5 VVITNWVHPEVIELLKPSCEVIANPSKEALSREEILQRAKDAEALMVFMPDTIDEAFLRE 64
Query: 269 GVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPAST 448
KLK++ A G DN DV + +G+ P + E+T L++ L R ++
Sbjct: 65 CPKLKIIAAALKGYDNFDVAACTHRGIWFTIVPSLLSAPTAEITIGLLIGLGRQMLEGDR 124
Query: 449 ALKAGRWD--RALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPF-VSADQC 619
++ G++ R + LA +TL I+G+G +G+ +A R+ F M ++ DP + +Q
Sbjct: 125 FIRTGKFTGWRPQFYSLGLANRTLGIVGMGALGKAIAGRLAGFEMQLLYSDPVALPPEQE 184
Query: 620 AQFHCTKMELEDIWPLADYITLHTPLIXSTRNFINAD 730
A + +++ E + +D++ L PL +T + INA+
Sbjct: 185 ATGNISRVPFETLIESSDFVVLVVPLQPATLHLINAN 221
>UniRef50_Q04DF1 Cluster: Lactate dehydrogenase related enzyme; n=1;
Oenococcus oeni PSU-1|Rep: Lactate dehydrogenase related
enzyme - Oenococcus oeni (strain BAA-331 / PSU-1)
Length = 311
Score = 91.5 bits (217), Expect = 2e-17
Identities = 53/182 (29%), Positives = 94/182 (51%), Gaps = 1/182 (0%)
Frame = +2
Query: 167 KAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKG 346
+A K+E ++++ +V + L LK++ R G G DN+D AG+ G
Sbjct: 26 EAPDDKQETILKVGKDADGIVLMTDPFDNQTLTKFTNLKIIARHGVGFDNVDEKFAGEHG 85
Query: 347 VGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRAL-YTGSELAGKTLAIL 523
V V P ANA + E T +L L++++ S ++ G + L + G +L+ K + ++
Sbjct: 86 VYVTITPMANASTVAETTIAEILDLSKNLTKISDEMRQGNFAYKLDHMGFDLSHKKIGVM 145
Query: 524 GLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYITLHTPLIX 703
G GR+GR+VA + A GM+++ FDPFV + + ++ + + +D ITLH +
Sbjct: 146 GYGRIGRQVAEKANALGMDVLIFDPFVKETKIGKL----VDRDTLISQSDVITLHLAVTD 201
Query: 704 ST 709
T
Sbjct: 202 QT 203
>UniRef50_A1UEI9 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=5; Mycobacterium|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Mycobacterium sp. (strain KMS)
Length = 321
Score = 91.5 bits (217), Expect = 2e-17
Identities = 69/190 (36%), Positives = 93/190 (48%), Gaps = 7/190 (3%)
Frame = +2
Query: 179 SKEELLMEIPNHDALVVRSATQVTKEVLDA-GVKLKVVGRAGAGVDNIDVDSAGKKGVGV 355
+++EL A VV +V E+LDA G L+VV G DNIDV +A GV V
Sbjct: 38 TRDELAAGFTGACAAVVTLTERVDAEILDAAGDGLRVVANVAVGYDNIDVAAAHAAGVTV 97
Query: 356 INAPGANALSACELTCTLMLVLARHVVPASTALKAGR---WDRALYTGSEL-AGKTLAIL 523
N PG + + T L+L + R VV L++ R W + TG ++ AG TL IL
Sbjct: 98 TNTPGVLDNATADHTFALILAVTRRVVDGDRFLRSRRPWIWGPRMLTGLDVSAGATLGIL 157
Query: 524 GLGRVGREVATRMYAFGMNIIGFD--PFVSADQCAQFHCTKMELEDIWPLADYITLHTPL 697
G GR+GR VA R AF M ++ AD F T L D +D + + TPL
Sbjct: 158 GYGRIGRAVARRARAFDMTVLATSRRRTSGADDDVWFVDTDTLLAD----SDVVCVLTPL 213
Query: 698 IXSTRNFINA 727
TR+ I+A
Sbjct: 214 TPETRHLIDA 223
>UniRef50_A4FIJ9 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Saccharopolyspora erythraea NRRL 2338|Rep:
D-3-phosphoglycerate dehydrogenase - Saccharopolyspora
erythraea (strain NRRL 23338)
Length = 322
Score = 91.1 bits (216), Expect = 3e-17
Identities = 53/164 (32%), Positives = 84/164 (51%)
Frame = +2
Query: 242 QVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVL 421
++ +LDA +++ G D +D +A ++G+ V N PG NA + + T ML L
Sbjct: 62 RIDAALLDAMPNCRLIQSVAVGFDGVDHVAAAERGIPVANLPGFNADAVADWTVGAMLHL 121
Query: 422 ARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPF 601
RH ++ G W G +L+ T+AILG G +GR VA R+ FG I+ DPF
Sbjct: 122 LRHYAAGHRKVEQGGWGPEGLRGRDLSALTVAILGFGNIGRAVARRLDGFGAEIVVHDPF 181
Query: 602 VSADQCAQFHCTKMELEDIWPLADYITLHTPLIXSTRNFINADV 733
S + Q+ + LE+ AD ++LH PL +TR + ++
Sbjct: 182 PS-EPGRQY----VALEEAVARADVLSLHMPLNDATRGLLGDEL 220
>UniRef50_Q76KF5 Cluster: D-phosphoglycerate dehydrogenase; n=2;
Entamoeba histolytica|Rep: D-phosphoglycerate
dehydrogenase - Entamoeba histolytica
Length = 299
Score = 91.1 bits (216), Expect = 3e-17
Identities = 58/184 (31%), Positives = 96/184 (52%)
Frame = +2
Query: 182 KEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVIN 361
KE+++ I + D ++VRS ++ +E++ AG K+K++ RAGAG DNID+++ + + V+N
Sbjct: 39 KEDVIERIKDADGVIVRS-DKIDEEIIKAGEKVKIIVRAGAGYDNIDIEACNQGKIVVMN 97
Query: 362 APGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVG 541
PG N EL +M+ R K G+ G EL KTL I G G VG
Sbjct: 98 TPGQNRNGVAELCIGMMIFGFR------KGFKEGK-------GRELKDKTLGICGCGYVG 144
Query: 542 REVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYITLHTPLIXSTRNFI 721
+ V GM I +DPF++ + + ++E+++ I+LH PL T+ I
Sbjct: 145 KRVKEIAEGIGMKIKVYDPFITTENQVK------KIEELFEECQVISLHLPLTKETKGKI 198
Query: 722 NADV 733
++
Sbjct: 199 GYEL 202
>UniRef50_A7CR80 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase NAD-binding; n=1; Opitutaceae bacterium
TAV2|Rep: D-isomer specific 2-hydroxyacid dehydrogenase
NAD-binding - Opitutaceae bacterium TAV2
Length = 355
Score = 90.6 bits (215), Expect = 3e-17
Identities = 57/191 (29%), Positives = 93/191 (48%), Gaps = 6/191 (3%)
Frame = +2
Query: 176 ISKEELLMEIPNHDALVVRSATQVTKEVLDAGV--KLKVVGRAGAGVDNIDVDSAGKKGV 349
+S+ EL+ +P D ++ T V +AG +LK + G GVDN+D + + G+
Sbjct: 79 LSEAELIELVPQFDGWIIGD-DPATARVFEAGKAGRLKAAVKWGVGVDNVDFAACQRLGL 137
Query: 350 GVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGL 529
+ N PG ++ ++ LAR +KAG W ++ G LAGKT+A+ G
Sbjct: 138 PISNTPGMFGREVADVAVGYVIALARQTFAIDRTVKAGGWIKS--AGISLAGKTVALAGF 195
Query: 530 GRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPL----ADYITLHTPL 697
G +GR A R++A M I+ +DPF A + +E +WP AD+I + L
Sbjct: 196 GDIGRNTARRLFAAEMKIVAYDPFFKAASGLE----AVE-PAVWPQRMEEADFIVITCAL 250
Query: 698 IXSTRNFINAD 730
R+ + +D
Sbjct: 251 TKENRHMLGSD 261
>UniRef50_A6PPS4 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Victivallis vadensis
ATCC BAA-548|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding - Victivallis vadensis ATCC
BAA-548
Length = 316
Score = 90.6 bits (215), Expect = 3e-17
Identities = 57/173 (32%), Positives = 81/173 (46%), Gaps = 1/173 (0%)
Frame = +2
Query: 212 HDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSAC 391
H V+ E+ DA K V+ R G G DNI++ A +KG+ N PGA S
Sbjct: 44 HAKYVIVGGAPYRNELYDAVPKGGVIARFGIGCDNINLPRAAEKGIYCTNTPGALEQSVA 103
Query: 392 ELTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVAT-RMYA 568
E ++L+ AR + A+ + G W TG ELAGKTLA++G G +G VA
Sbjct: 104 ECAIGMILLAARQFIAAADDCRNGLWQP--QTGCELAGKTLAVIGCGAIGSRVAAIAKNG 161
Query: 569 FGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYITLHTPLIXSTRNFINA 727
FGM++ G C K D AD+++LH P N+++A
Sbjct: 162 FGMSVTGVIRSAPRPDCPADRFVK-NWSDAVADADFVSLHIPGSPENLNYVSA 213
>UniRef50_A2F8V0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, putative; n=3; Trichomonas vaginalis
G3|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
putative - Trichomonas vaginalis G3
Length = 396
Score = 90.6 bits (215), Expect = 3e-17
Identities = 54/165 (32%), Positives = 85/165 (51%), Gaps = 1/165 (0%)
Frame = +2
Query: 95 VLIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV 274
+LI D + K E+L A G I++ L EI +++ L+VRS V ++A
Sbjct: 4 ILIADSLSPKAVEMLKAAGHEVRMDPSITQASLANEISDYNVLIVRSKV-VNAAAIEAAK 62
Query: 275 KLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTAL 454
L ++ RAGAGV+ IDV++A KGV V N PG N + EL ++ R + + L
Sbjct: 63 GLNLIIRAGAGVNTIDVNAASAKGVLVCNTPGMNNDAVAELAFGHIVCCDRCITTNTAHL 122
Query: 455 KAGRWDRALYTGSE-LAGKTLAILGLGRVGREVATRMYAFGMNII 586
+ G W + L+ E L +TL I+G G + + + F MN++
Sbjct: 123 RNGEWRKKLFLTCEGLRDRTLGIVGRGNIAKSMIRIAKGFMMNVV 167
>UniRef50_Q89EL0 Cluster: Blr7063 protein; n=1; Bradyrhizobium
japonicum|Rep: Blr7063 protein - Bradyrhizobium
japonicum
Length = 387
Score = 90.2 bits (214), Expect = 5e-17
Identities = 51/183 (27%), Positives = 86/183 (46%), Gaps = 3/183 (1%)
Frame = +2
Query: 155 ATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSA 334
A +A ++ E + N DA+ + +TK ++DA KV+ GVD++DV +A
Sbjct: 73 AEIIEAPANEAEFIAAAKNADAIYAKGIP-ITKSIIDALESCKVITLGSVGVDSVDVKAA 131
Query: 335 GKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDR---ALYTGSELAG 505
+G+ V N P + L+L R +V +++GRW AL L G
Sbjct: 132 TARGIPVTNIPDTFIEEVADHAMMLLLAGFRRLVEQDRMVRSGRWAEGRPALLKIPRLMG 191
Query: 506 KTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYITL 685
+TL + GRV R VA R FG+ ++ +DPF+ L ++ +D++++
Sbjct: 192 QTLGFISFGRVARAVAKRAAPFGLRMMAYDPFIQETLMYDHGVIPATLNEVLSQSDFVSM 251
Query: 686 HTP 694
H P
Sbjct: 252 HAP 254
>UniRef50_Q9HK29 Cluster: 2-hydroxyacid dehydrogenase related
protein; n=4; Thermoplasmatales|Rep: 2-hydroxyacid
dehydrogenase related protein - Thermoplasma acidophilum
Length = 309
Score = 90.2 bits (214), Expect = 5e-17
Identities = 54/172 (31%), Positives = 95/172 (55%), Gaps = 1/172 (0%)
Frame = +2
Query: 215 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 394
+ L+V + T V ++L +L+ V A G DN+D+++ K G+ V N P A+A S E
Sbjct: 41 EILIVTTFTPVNGDLLKKMPRLRFVQVASIGYDNVDMNAMKKNGIMVSNIPTASADSVAE 100
Query: 395 LTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFG 574
+++L L + +++GRW R + S+L GKT I+G+G +GR +A R+ F
Sbjct: 101 HALSMVLSLIKDQRFLDAEIRSGRWPR-ITRSSDLMGKTFGIVGMGSIGRALAARLLPFK 159
Query: 575 MNIIGFD-PFVSADQCAQFHCTKMELEDIWPLADYITLHTPLIXSTRNFINA 727
+ II D +S + ++ T + L+ + +D I++H PL +TR+ N+
Sbjct: 160 VAIIYNDTKRMSEAEEEEYGATFVSLDRLLSDSDVISVHVPLNETTRHMFNS 211
>UniRef50_A7D498 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Halorubrum
lacusprofundi ATCC 49239|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, NAD-binding - Halorubrum
lacusprofundi ATCC 49239
Length = 324
Score = 90.2 bits (214), Expect = 5e-17
Identities = 52/185 (28%), Positives = 92/185 (49%), Gaps = 1/185 (0%)
Frame = +2
Query: 179 SKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVI 358
S E L+ DA+V T VT E L + L+ V RA GVDN+DV +A ++GV V
Sbjct: 38 STERLIEAAAGADAVVTDIDTPVTDEALGR-LDLRAVVRAAVGVDNVDVGAAAERGVTVT 96
Query: 359 NAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTG-SELAGKTLAILGLGR 535
AP + +L+L R + + W + ++ T+ + G
Sbjct: 97 RAPDYCTDEVAIHSVSLLLACLRSLKAYDDHVVDDGWSWEVGRPIRRVSASTVGFVSFGP 156
Query: 536 VGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYITLHTPLIXSTRN 715
+ R A ++ F +++ +DPFV AD+ A++ K + ++++ AD++ ++ PL +TR
Sbjct: 157 IARRAAEQIAGFDADLVAYDPFVEADEMAEYGVEKADFDELFDRADHVGVYAPLTDATRG 216
Query: 716 FINAD 730
++AD
Sbjct: 217 MVDAD 221
>UniRef50_Q89LI6 Cluster: Blr4558 protein; n=6;
Bradyrhizobiaceae|Rep: Blr4558 protein - Bradyrhizobium
japonicum
Length = 329
Score = 89.8 bits (213), Expect = 6e-17
Identities = 61/193 (31%), Positives = 92/193 (47%), Gaps = 2/193 (1%)
Frame = +2
Query: 155 ATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSA 334
A AK + L P H V AT + L+A +KVV R G G D +DV +
Sbjct: 34 ANLISAKDFQALLKSHAPVHG--VALGATAFGETELEASKDMKVVTRIGVGYDAVDVPAL 91
Query: 335 GKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW-DRALYTGSELAGKT 511
++ V ++ A AN+ S E +ML LA+ + +K G+W DR +L GKT
Sbjct: 92 SRRKVPLMVAGSANSPSVAEQALFMMLTLAKRAQEMHSCVKDGKWADRLGMLPFDLYGKT 151
Query: 512 LAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQC-AQFHCTKMELEDIWPLADYITLH 688
+ I+G GR+G A R A M + +DP+ A + A + +L+ P AD++T+H
Sbjct: 152 VLIIGFGRIGTRTAKRCLAMEMRVQVYDPYKPAAEIKAAGYEPVADLDAALPHADFVTIH 211
Query: 689 TPLIXSTRNFINA 727
P T +A
Sbjct: 212 CPKTPETVGLFDA 224
>UniRef50_Q6AMI7 Cluster: Related to D-3-phosphoglycerate
dehydrogenase; n=1; Desulfotalea psychrophila|Rep:
Related to D-3-phosphoglycerate dehydrogenase -
Desulfotalea psychrophila
Length = 393
Score = 89.8 bits (213), Expect = 6e-17
Identities = 59/166 (35%), Positives = 88/166 (53%), Gaps = 15/166 (9%)
Frame = +2
Query: 278 LKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHV------VP 439
L V RAGAG +N++V+ A KKG+ V N PGANA + +L ++ V R++
Sbjct: 51 LLAVARAGAGTNNVNVERATKKGICVFNTPGANANAVVDLVFPMLGVWKRNIFNGINFCK 110
Query: 440 ASTALKAGRWD------RALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPF 601
+ TA+ + D ++ Y G E+AGK L ++GLG++G +A MN+ GFDP
Sbjct: 111 SLTAVDPDKVDSVVEAQKSAYKGEEIAGKNLTVVGLGQIGVRLANGGIQRLMNVKGFDPA 170
Query: 602 VSADQCAQFH---CTKMELEDIWPLADYITLHTPLIXSTRNFINAD 730
+ + Q L+D AD I+LH PL TRN +NA+
Sbjct: 171 PALENIHQLSPQVRVCRALKDAVSDADVISLHLPLNDRTRNLVNAE 216
>UniRef50_A3PPC6 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=4; Rhodobacteraceae|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Rhodobacter sphaeroides (strain ATCC 17029
/ ATH 2.4.9)
Length = 331
Score = 89.8 bits (213), Expect = 6e-17
Identities = 69/212 (32%), Positives = 99/212 (46%), Gaps = 2/212 (0%)
Frame = +2
Query: 98 LIVDGVGAKCAELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVK 277
LIV + L A GIA + + DA++ R A + AG +
Sbjct: 4 LIVQPIHEAGLAALRAAGIAPILCPAPDMATVARHMAGIDAVITRDAG-LDAAAFAAGDR 62
Query: 278 LKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALK 457
L+ V GAG D +D ++A +KGV V N PGANA S EL L L +AR + A AL+
Sbjct: 63 LRAVVVHGAGHDPVDKEAAARKGVVVANTPGANARSVAELAVGLALAVARRIPAADRALR 122
Query: 458 AGRWD-RALYTGSELAGKTLAILGLGRVGREVATRM-YAFGMNIIGFDPFVSADQCAQFH 631
G+ R SEL G+T ++G G GRE + AF M ++ P V + +
Sbjct: 123 EGKTGFRESARFSELRGRTALVVGWGASGRETGRMLAQAFDMRLLVHSPRVPRIEGGE-- 180
Query: 632 CTKMELEDIWPLADYITLHTPLIXSTRNFINA 727
L + AD ++LHTPL T + ++A
Sbjct: 181 -RVASLAEGLAAADLVSLHTPLRPETHHMMDA 211
>UniRef50_A6G5P3 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Plesiocystis pacifica SIR-1|Rep: D-3-phosphoglycerate
dehydrogenase - Plesiocystis pacifica SIR-1
Length = 405
Score = 89.4 bits (212), Expect = 8e-17
Identities = 52/167 (31%), Positives = 83/167 (49%)
Frame = +2
Query: 227 VRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCT 406
VRS T+V + +A +L VG G D ID++ A + GV V NAP +N S EL
Sbjct: 49 VRSKTKVRAPIFEAVPRLAAVGAFCIGTDQIDLEVAAQSGVAVFNAPFSNTRSVAELVIA 108
Query: 407 LMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNII 586
++ L+R + S A GRW + E+ GKTL I+G G +G +++ A G+ +
Sbjct: 109 EIVCLSRQLFERSWAAHEGRWRKDAKGAHEVRGKTLGIIGYGHIGSQLSVLAEAMGLR-V 167
Query: 587 GFDPFVSADQCAQFHCTKMELEDIWPLADYITLHTPLIXSTRNFINA 727
+ V+ ++ L+ + +D+++LH P TRN A
Sbjct: 168 RYHDIVNKLPLGNASASE-SLDALLAGSDFVSLHVPNTPQTRNMFGA 213
>UniRef50_A0FZA8 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=3; Burkholderia|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Burkholderia phymatum STM815
Length = 321
Score = 89.4 bits (212), Expect = 8e-17
Identities = 49/170 (28%), Positives = 86/170 (50%), Gaps = 4/170 (2%)
Frame = +2
Query: 227 VRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCT 406
+ + ++ E L +LKV+ G D DVD K+G+ + N P S + +
Sbjct: 46 IGTGVKMNAETLADASRLKVLSTVSVGFDAFDVDYLNKRGILLTNTPDVLTESTADTAFS 105
Query: 407 LMLVLARHVVPASTALKAGRWDRALYT---GSELAGKTLAILGLGRVGREVATR-MYAFG 574
L+L+ AR + + +KAG+W + + G ++ KTL I+GLGR+G VA R F
Sbjct: 106 LILLTARRLAELAAFVKAGKWTKKIAEDRFGVDVHHKTLGIVGLGRIGTSVARRAALGFQ 165
Query: 575 MNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYITLHTPLIXSTRNFIN 724
MN++ D V+ ++ ++ +++ +D++ L PL TRN I+
Sbjct: 166 MNVLYVDQGVNEKAEREYGAKRVSFDELLKTSDFVLLQAPLTPETRNLIS 215
>UniRef50_Q2S4U0 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD binding domain protein; n=2; cellular
organisms|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD binding domain protein - Salinibacter
ruber (strain DSM 13855)
Length = 321
Score = 89.0 bits (211), Expect = 1e-16
Identities = 57/188 (30%), Positives = 94/188 (50%), Gaps = 5/188 (2%)
Frame = +2
Query: 179 SKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVI 358
S +EL+ D L+ A +T+ + +A L++V + GVDNID+++A V V
Sbjct: 36 SVDELIALADGADVLLSVLADPITEALFEARPGLQMVSQYAVGVDNIDLEAAEAHDVAVT 95
Query: 359 NAPGANALSACELTCTLMLVLARHVVPASTALKAG---RWDRALYTGSELAGKTLAILGL 529
+ PG + + L+L ARHV A ++ G RW+ G ELA KT+ I+G+
Sbjct: 96 HTPGVLTDATADQAWALLLAAARHVPAADRYVRDGRFERWETTHLMGMELARKTIGIVGM 155
Query: 530 GRVGREVATRMYAFGMNIIGFDPFVSADQCA--QFHCTKMELEDIWPLADYITLHTPLIX 703
GR+G VA R FGM +I + A+ Q + L ++ +D ++LH P
Sbjct: 156 GRIGTAVARRALGFGMEVI-YHNRTRANPTVERQVSARHVGLGELLTTSDVVSLHCPHND 214
Query: 704 STRNFINA 727
+ + ++A
Sbjct: 215 ESHHLLDA 222
>UniRef50_A6LZ51 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Clostridium
beijerinckii NCIMB 8052|Rep: D-isomer specific
2-hydroxyacid dehydrogenase, NAD-binding - Clostridium
beijerinckii NCIMB 8052
Length = 320
Score = 89.0 bits (211), Expect = 1e-16
Identities = 59/186 (31%), Positives = 97/186 (52%), Gaps = 3/186 (1%)
Frame = +2
Query: 185 EELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINA 364
+E+L I + L+ +V +L KLK+V + GAG DN+D+D+ + G+ NA
Sbjct: 40 KEMLHHIEDCQVLIPEHI-KVDCSLLSIAKKLKLV-QTGAGFDNVDIDACTQYGIWAANA 97
Query: 365 PGANALSACELTCTLMLVLARHVVPASTALKAGRWDRAL-YTGSELAGKTLAILGLGRVG 541
G NA + E L+L +++ + +K + L YTGSEL GKT+ I+G G VG
Sbjct: 98 AGVNAQAVAEHVMALILSYYKNIPFLDSFIKNKIDENELQYTGSELKGKTIGIIGFGAVG 157
Query: 542 REVATRMYAFGMNIIGF--DPFVSADQCAQFHCTKMELEDIWPLADYITLHTPLIXSTRN 715
++VA F MNI+ + +P V +D + + + + +D +++H L T+
Sbjct: 158 KKVAEFCRVFDMNILVYARNPVVQSDSFVKM----TDFDTLVGASDIVSVHVSLNQQTKQ 213
Query: 716 FINADV 733
IN DV
Sbjct: 214 LINKDV 219
>UniRef50_A5V6T9 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=1; Sphingomonas wittichii
RW1|Rep: D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Sphingomonas wittichii RW1
Length = 317
Score = 89.0 bits (211), Expect = 1e-16
Identities = 60/178 (33%), Positives = 90/178 (50%), Gaps = 6/178 (3%)
Frame = +2
Query: 215 DALVVRSATQVTKEVLDAGVKLKVVGRA--GAGVDNIDVDSAGKKGVGVINAPGANALSA 388
D L++ A +V L AG+ V A G+D+ID+D+ +G+ + N PG + +
Sbjct: 47 DVLLLSPAVRVDAAFL-AGLPASVGALATYSVGLDHIDLDAVRARGLPMFNTPGILSNAV 105
Query: 389 CELTCTLMLVLARHVVPASTALKAGRWD---RALYTGSELAGKTLAILGLGRVGREVATR 559
+ L+L R + A+ L+ GRW + G ELAG+TL I GLG +GR VA R
Sbjct: 106 ADQAMLLLLAATRRMAEATALLREGRWTDLWSSHILGVELAGRTLGIYGLGDIGRRVARR 165
Query: 560 MYAFGMNIIGFDPFVSADQC-AQFHCTKMELEDIWPLADYITLHTPLIXSTRNFINAD 730
AFGM ++ + + D+ A F T E+ AD + L P TRNF+N +
Sbjct: 166 ATAFGMRLVYHNRRRAVDEAGATFAAT---AEEFLASADILLLAAPSTGETRNFLNRE 220
>UniRef50_Q98LH4 Cluster: Phosphoglycerate dehydrogenase; n=3;
Mesorhizobium loti|Rep: Phosphoglycerate dehydrogenase -
Rhizobium loti (Mesorhizobium loti)
Length = 341
Score = 88.6 bits (210), Expect = 1e-16
Identities = 55/187 (29%), Positives = 98/187 (52%), Gaps = 2/187 (1%)
Frame = +2
Query: 173 KISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVG 352
+ +++EL+ + AL+ S T++T+ V+ A L+ + + G GVD+ID+D+A + G+
Sbjct: 45 RFTEDELIAKAHGCIALMGASGTRITRRVMQALPDLRYISKYGIGVDSIDIDAATEHGIL 104
Query: 353 VINAPG-ANALSACELTCTLMLVLARHV-VPASTALKAGRWDRALYTGSELAGKTLAILG 526
V + P + E LML +A+ + ++ G W R L G+ L G T+ I+G
Sbjct: 105 VSSTPNDFQIFTVSEHAVALMLAVAKQLGTWTPEFMRRGGW-RGLTHGATLRGATVGIVG 163
Query: 527 LGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYITLHTPLIXS 706
LGR+GR VA R+ + I+ +DPF+ A ++ + +D++TLH
Sbjct: 164 LGRIGRGVAQRLSGWEARILAYDPFLKE---APPGIELVDFPTLVEQSDFLTLHATPSPD 220
Query: 707 TRNFINA 727
+ +NA
Sbjct: 221 NHHILNA 227
>UniRef50_Q2LUG0 Cluster: 2-hydroxyacid dehydrogenase, D-isomer
specific; n=1; Syntrophus aciditrophicus SB|Rep:
2-hydroxyacid dehydrogenase, D-isomer specific -
Syntrophus aciditrophicus (strain SB)
Length = 326
Score = 88.6 bits (210), Expect = 1e-16
Identities = 52/178 (29%), Positives = 91/178 (51%), Gaps = 6/178 (3%)
Frame = +2
Query: 215 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 394
+AL+V + +T+ LD L+V+G G++++ + S +G+ ++N G + +
Sbjct: 61 EALIVLLSEPLTEADLDLCPNLRVIGTYSVGINHLPITSCQSRGIRIVNTQGVLTDATAD 120
Query: 395 LTCTLMLVLARHVVPASTALKAGRWD---RALYTGSELAGKTLAILGLGRVGREVATRMY 565
L TL+L L R V +++G W L G+ L GKT ILG G +GR A R++
Sbjct: 121 LALTLLLSLTRRVREGEALVRSGHWKGWAPDLLLGTGLTGKTCGILGSGPIGRAFARRVW 180
Query: 566 AFGMNIIGFDPFVSADQCAQFH---CTKMELEDIWPLADYITLHTPLIXSTRNFINAD 730
A GM +I F + F ++ L+++ +D ++LH PL +TR +N +
Sbjct: 181 AIGMKVI-FWNREGNQKPVDFGVDIAARLPLDELLRQSDVLSLHCPLTDTTRGLLNRE 237
>UniRef50_Q5ZYW9 Cluster: D-3-phosphoglycerate dehydrogenase; n=3;
Legionella pneumophila|Rep: D-3-phosphoglycerate
dehydrogenase - Legionella pneumophila subsp.
pneumophila (strain Philadelphia 1 /ATCC 33152 / DSM
7513)
Length = 295
Score = 88.2 bits (209), Expect = 2e-16
Identities = 60/213 (28%), Positives = 109/213 (51%), Gaps = 3/213 (1%)
Frame = +2
Query: 95 VLIVDGVGAKCAEL---LNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLD 265
+ +V+ +G E+ L + I + S E+L+ + + D + + + +++ V++
Sbjct: 3 IAVVEPIGIAMQEIRSELPGHTIIECDSRQWSDEQLIDFVKDADIIALTNR-RLSAAVIN 61
Query: 266 AGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPAS 445
+ ++L+++ A AG+D+ID D+ K+ + V NA G + EL LM+ LARH+ +
Sbjct: 62 SALRLQLIAVAFAGIDHIDRDAVSKRNIPVKNAAGYANTAVSELVFGLMISLARHIPDNN 121
Query: 446 TALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQ 625
+ R TG EL K L I+G G +G EVA AF M I +D
Sbjct: 122 QRI---REQGITNTGIELKNKVLGIVGYGAIGAEVARLAKAFQMTTIIYD---------- 168
Query: 626 FHCTKMELEDIWPLADYITLHTPLIXSTRNFIN 724
+++ L+D++ +D++TLH PL T+ +N
Sbjct: 169 -RKSQVTLDDLFSQSDFVTLHVPLTNETKGMVN 200
>UniRef50_Q1MQK2 Cluster: Phosphoglycerate dehydrogenase and related
dehydrogenases; n=1; Lawsonia intracellularis
PHE/MN1-00|Rep: Phosphoglycerate dehydrogenase and
related dehydrogenases - Lawsonia intracellularis
(strain PHE/MN1-00)
Length = 302
Score = 88.2 bits (209), Expect = 2e-16
Identities = 57/177 (32%), Positives = 94/177 (53%), Gaps = 3/177 (1%)
Frame = +2
Query: 122 KCAELLNAYGIATTTKAK---ISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVG 292
K ELL+ GI + ++ EEL+ I ++V S + K+VL+ +LK +
Sbjct: 16 KPLELLSQAGIEYILNEQGYHLTDEELIQIIDGCAGIIVGSEP-LPKKVLETNPRLKTIA 74
Query: 293 RAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD 472
G +DNIDV+ A +K + + N P A++ E T L+L L R + +++G W
Sbjct: 75 CCGKHLDNIDVEYAQEKNIIIYNPPKGYAIAVAEFTVGLILSLIRQIPYQDKEVRSGVWH 134
Query: 473 RALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKM 643
+ + G+ L GK + I+GLG+VG+ VA R+ FG++I DP V + +F K+
Sbjct: 135 KRI--GNLLHGKRVGIIGLGQVGKAVAERLLPFGVDIAYNDPNVYSTTFQKFDLDKL 189
>UniRef50_Q0FY56 Cluster: Putative phosphoglycerate dehydrogenase
protein; n=1; Fulvimarina pelagi HTCC2506|Rep: Putative
phosphoglycerate dehydrogenase protein - Fulvimarina
pelagi HTCC2506
Length = 322
Score = 88.2 bits (209), Expect = 2e-16
Identities = 59/183 (32%), Positives = 91/183 (49%), Gaps = 5/183 (2%)
Frame = +2
Query: 200 EIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANA 379
E+ +VVR A + L+ KL+ + R GAG+D I V +A + G+ V N P NA
Sbjct: 35 ELAEASFVVVRRA--IPAGALENAPKLRALVRHGAGLDFIPVQAASRLGIAVTNTPSVNA 92
Query: 380 LSACELTCTLMLVLARHVVPASTALKAGRWD--RALYTGS-ELAGKTLAILGLGRVGREV 550
S E L++ LAR +V ++ W RA GS E+AGK L ++G G +G+ +
Sbjct: 93 KSVAEHVFGLIICLARRIVENDAGIRRNEWHALRAAAPGSCEIAGKALGLIGYGGIGQAI 152
Query: 551 A-TRMYAFGMNIIGFDPFVSADQ-CAQFHCTKMELEDIWPLADYITLHTPLIXSTRNFIN 724
A FGMN++ + D+ FH L D+ AD + + PL TRN ++
Sbjct: 153 AQIGKLGFGMNVLAATRWPREDEDGVSFH----PLTDVAAKADILVVACPLSEETRNLVS 208
Query: 725 ADV 733
++
Sbjct: 209 EEI 211
>UniRef50_A7BQE7 Cluster: D-3-phosphoglycerate dehydrogenase; n=1;
Beggiatoa sp. PS|Rep: D-3-phosphoglycerate dehydrogenase
- Beggiatoa sp. PS
Length = 302
Score = 88.2 bits (209), Expect = 2e-16
Identities = 53/185 (28%), Positives = 93/185 (50%), Gaps = 3/185 (1%)
Frame = +2
Query: 179 SKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVI 358
+KE LL I + D ++++S ++ KE + A LK+V AG G+D+I +D K+G+
Sbjct: 30 NKERLLEVIEDKDVVILKSRIELDKEAIFAAKHLKLVVMAGIGLDHICLDELKKRGIAWF 89
Query: 359 NAPGANALSACELTCTLMLVLARHVVPASTALKAGR---WDRALYTGSELAGKTLAILGL 529
N P +A EL L L LAR + + L+ W R G L + I+G
Sbjct: 90 NIPDLSARGVAELVLGLTLSLARKICLGDSLLRNNEFKLWKRPELMGFNLQDRLFGIVGY 149
Query: 530 GRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYITLHTPLIXST 709
G++G+E+A+ FGM + + S + + + T + +++ +D I++H PL T
Sbjct: 150 GKIGKEMASVAKCFGMKVQVY-VRNSDHKTFEQNITPVTFQNLLKTSDVISIHVPLTDET 208
Query: 710 RNFIN 724
+ +
Sbjct: 209 KGMFS 213
>UniRef50_A1AQ02 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=3; Bacteria|Rep: D-isomer
specific 2-hydroxyacid dehydrogenase, NAD-binding -
Pelobacter propionicus (strain DSM 2379)
Length = 318
Score = 88.2 bits (209), Expect = 2e-16
Identities = 59/187 (31%), Positives = 96/187 (51%), Gaps = 10/187 (5%)
Frame = +2
Query: 200 EIPNH---DALVVRSATQVTKEVLDA-GVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAP 367
EIP+ +V+ + +E++ +K++ AG G +NID+ +A +G+GV N P
Sbjct: 39 EIPSRVEGQTIVITKELPLGRELIHCFPASVKLICEAGTGYNNIDIAAARSRGIGVCNVP 98
Query: 368 GANALSACELTCTLMLVLARHVVPASTALKAGRWD---RALYTGS-ELAGKTLAILGLGR 535
+ + +L T ML L+ +V T L+ G D ++L EL GKTL ++G G
Sbjct: 99 SYSTDAVAQLAITFMLNLSASLVQQQTMLRRGNLDNFQKSLQLPHFELNGKTLGVIGFGE 158
Query: 536 VGREVATRMYAFGMNII--GFDPFVSADQCAQFHCTKMELEDIWPLADYITLHTPLIXST 709
+GR V GM II P D +F + LE++ +D+++LH PL +T
Sbjct: 159 IGRRVIAIARTLGMKIIVHSRTPRPELDPDLRF----VSLEELLATSDFVSLHCPLNDAT 214
Query: 710 RNFINAD 730
R+ INA+
Sbjct: 215 RHVINAE 221
>UniRef50_Q20595 Cluster: Putative uncharacterized protein; n=3;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 727
Score = 88.2 bits (209), Expect = 2e-16
Identities = 70/194 (36%), Positives = 99/194 (51%), Gaps = 10/194 (5%)
Frame = +2
Query: 179 SKEELLMEIPNHD-ALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGV 355
S +E+ ++ N A ++ + ++ KE L+ LKVV R G G+DNIDV +A + G+ V
Sbjct: 209 STQEIHEKVLNEAVAALMYHSIKLEKEDLEKFKVLKVVFRIGYGIDNIDVKAATELGIAV 268
Query: 356 INAPGANALSACELTCTLMLVLAR----HVVPASTALKAGRWD--RALYTGS-ELAGKTL 514
+APG + T +L+L L R H S K D R GS ++ G L
Sbjct: 269 CHAPGDYVEDVADSTLSLILDLFRRTYWHAKSYSETRKTIGADQVRENAVGSKKVRGSVL 328
Query: 515 AILGLGRVGREVATRMYAFGMNIIGFDPFV--SADQCAQFHCTKMELEDIWPLADYITLH 688
ILG GRVG V R AFG++II +DPFV D+ F +++ +D I+LH
Sbjct: 329 GILGCGRVGTAVGLRARAFGLHIIFYDPFVREGHDKALGFE-RVYTMDEFMSRSDCISLH 387
Query: 689 TPLIXSTRNFINAD 730
L TR INAD
Sbjct: 388 CNLGDETRGIINAD 401
>UniRef50_Q6A895 Cluster: D-3-phosphoglycerate dehydrogenase; n=2;
Actinomycetales|Rep: D-3-phosphoglycerate dehydrogenase
- Propionibacterium acnes
Length = 417
Score = 87.8 bits (208), Expect = 2e-16
Identities = 53/204 (25%), Positives = 103/204 (50%), Gaps = 3/204 (1%)
Frame = +2
Query: 86 IKSVLIVDGVGAKCAELLNAYGIATTTKAK-ISKEELLMEIPNHDALVVRSATQVTKEVL 262
+ L+++ + + L G ++ + +++L+ + D L +RS T+VT+ V+
Sbjct: 21 VMKALLLENIHDEAVRTLKKAGYEVERVSEALDEDDLISALDGVDLLGIRSRTRVTRRVV 80
Query: 263 DA-GVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVP 439
+A G KL VG G + +D+D+ + GV NAP +N S EL ++ LAR +
Sbjct: 81 EACGDKLHAVGAFCIGTNQMDLDALAEAGVPAFNAPYSNTRSVVELVMAEIIALARRLGD 140
Query: 440 ASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQC 619
+T + G W ++ E+ G+ L I+G G +G++++ A GM + +D AD
Sbjct: 141 RNTQMHNGVWRKSAIGSHEIRGRRLGIIGYGNIGQQLSVVAEAMGMQVFFYD---IADVL 197
Query: 620 AQFHCTKME-LEDIWPLADYITLH 688
+ K + +E++ + ++LH
Sbjct: 198 PMGNAHKCDSMEELLGSVETVSLH 221
>UniRef50_Q6KZ29 Cluster: Gluconate 2-dehydrogenase; n=3;
Archaea|Rep: Gluconate 2-dehydrogenase - Picrophilus
torridus
Length = 310
Score = 87.8 bits (208), Expect = 2e-16
Identities = 52/189 (27%), Positives = 94/189 (49%), Gaps = 4/189 (2%)
Frame = +2
Query: 179 SKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVI 358
S + L+ I + D +++ + ++ E++DA KLKV+ G D+IDV A + + +
Sbjct: 30 SHQWLMESINDADGILITLSDRIDSEIIDAAKKLKVISTYSVGYDHIDVKYALSRNIKIG 89
Query: 359 NAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRA----LYTGSELAGKTLAILG 526
P S + L++ +AR + + + +W+ G ++ GKTL ILG
Sbjct: 90 YTPDVLTESTADFIFGLIICIARRICSGYETIISNKWEYRWKPDFMLGHDVYGKTLGILG 149
Query: 527 LGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYITLHTPLIXS 706
LGR+G V R F MN+I ++ ++ H + L +++ +D+I + PL
Sbjct: 150 LGRIGHAVMRRASGFDMNVIYYN---RTERDVNGH---VGLNELFSRSDFIVITLPLNDE 203
Query: 707 TRNFINADV 733
TRN +N D+
Sbjct: 204 TRNIVNKDL 212
>UniRef50_A4AQJ2 Cluster: D-lactate dehydrogenase; n=1;
Flavobacteriales bacterium HTCC2170|Rep: D-lactate
dehydrogenase - Flavobacteriales bacterium HTCC2170
Length = 335
Score = 87.4 bits (207), Expect = 3e-16
Identities = 46/160 (28%), Positives = 84/160 (52%)
Frame = +2
Query: 245 VTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLA 424
V +++ D GVK + AG +NI + +A + G+ V NAP + + EL L++ +
Sbjct: 59 VLEKLRDLGVKY--ITLRSAGYNNIQIKAAKRFGLKVANAPDYSPNAIAELAVALLMTIN 116
Query: 425 RHVVPASTALKAGRWDRALYTGSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFV 604
R ++ A + A +D+ G +L KT+ ++G+GR+G + M+ FG NI+ D
Sbjct: 117 RKIIVADKQVHAHNFDQKNLLGCDLVHKTVGVIGVGRIGSVMVKIMHGFGCNILAHDLQP 176
Query: 605 SADQCAQFHCTKMELEDIWPLADYITLHTPLIXSTRNFIN 724
+ D ++ LE+++ +D I+LH PL T ++
Sbjct: 177 NGDLVEKYQVKYTSLEELYAQSDIISLHVPLTHETHYMVS 216
>UniRef50_Q4PK14 Cluster: Predicted D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=1; uncultured bacterium
MedeBAC49C08|Rep: Predicted D-isomer specific
2-hydroxyacid dehydrogenase family protein - uncultured
bacterium MedeBAC49C08
Length = 395
Score = 87.0 bits (206), Expect = 4e-16
Identities = 59/188 (31%), Positives = 93/188 (49%), Gaps = 15/188 (7%)
Frame = +2
Query: 215 DALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACE 394
DA+++RS E+ + +K + RAGAGV+NI V+ K G+ V N PGANA + E
Sbjct: 34 DAIILRSHKLQMSEIPSS---VKAIVRAGAGVNNIPVEECSKIGIPVFNTPGANANAVKE 90
Query: 395 LTCTLMLVLARHVVP-----------ASTALKAG-RWDRALYTGSELAGKTLAILGLGRV 538
+ +L+ +R + + LKA + + G EL L ++G+G +
Sbjct: 91 MVLAALLMSSRGIFDGVKFVHGIEDVSKENLKAHIESGKKSFKGRELKDGCLGVVGMGAI 150
Query: 539 GREVATRMYAFGMNIIGFDPFVSADQCAQFHC---TKMELEDIWPLADYITLHTPLIXST 709
G +VA GM +IGFDP ++ + K +E+I+ +DY+TLH P T
Sbjct: 151 GAKVAEMGVMLGMRVIGFDPQITVEAAWALPNEVERKETIEEIFKESDYVTLHVPANEHT 210
Query: 710 RNFINADV 733
IN D+
Sbjct: 211 TGMINKDL 218
>UniRef50_A0Y9Y1 Cluster: Glyoxylate reductase; n=2; unclassified
Gammaproteobacteria|Rep: Glyoxylate reductase - marine
gamma proteobacterium HTCC2143
Length = 326
Score = 87.0 bits (206), Expect = 4e-16
Identities = 51/192 (26%), Positives = 94/192 (48%), Gaps = 5/192 (2%)
Frame = +2
Query: 167 KAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKG 346
K I ++EL+ + D ++ ++ E++++ LK V GVD++DV + +G
Sbjct: 30 KGSIPRDELMARVEGVDGIICLLTERIDGELINSSKNLKAVSCVSVGVDHVDVGTLTARG 89
Query: 347 VGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRA-----LYTGSELAGKT 511
+ + + PG + +L L+L AR + ++ G W A + G +AGKT
Sbjct: 90 IPLGHTPGVLVDATADLAFGLLLAAARRIPQGDRHVRTGGWQGASWSPKAFLGCSVAGKT 149
Query: 512 LAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYITLHT 691
L I+GLG +G+ +A R F M +I + S + A + LE + +D+++++
Sbjct: 150 LGIIGLGDIGQALARRAAGFDMPVIAWSR--SGREVAGVR--TLSLEQVLDQSDFVSINV 205
Query: 692 PLIXSTRNFINA 727
L TR I+A
Sbjct: 206 ALTEETRGLIDA 217
>UniRef50_A0HB22 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase, NAD-binding; n=3; Burkholderiales|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase,
NAD-binding - Comamonas testosteroni KF-1
Length = 327
Score = 87.0 bits (206), Expect = 4e-16
Identities = 57/186 (30%), Positives = 91/186 (48%), Gaps = 3/186 (1%)
Frame = +2
Query: 179 SKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVI 358
S +L + + DA++ VTKE L +LK + A G DN D+ + + GV V
Sbjct: 36 SPSQLREYLVDADAMMAFMTDSVTKESLLNAPRLKTISCALKGYDNFDLRACAQAGVSVT 95
Query: 359 NAPGANALSACELTCTLMLVLARHVVPASTALKAG--RWDRALYTGSELAGKTLAILGLG 532
P EL L + R+V+ A +AG W ALY G+ L G +++GLG
Sbjct: 96 FVPDLLTEPTAELAIGLAIAAGRNVLQGDAATRAGYSGWRPALY-GTGLHGSVASVIGLG 154
Query: 533 RVGREVATRMYAFG-MNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYITLHTPLIXST 709
+VG+ + R+ FG ++G DP V DQ + L++ +DY+ L PL+ T
Sbjct: 155 KVGQAILARLAGFGCARLLGVDPSVRLDQ-----VELVTLDEAVSTSDYVFLAVPLVSDT 209
Query: 710 RNFINA 727
R+ +++
Sbjct: 210 RHLVDS 215
>UniRef50_Q5HW94 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=15;
Campylobacterales|Rep: D-isomer specific 2-hydroxyacid
dehydrogenase family protein - Campylobacter jejuni
(strain RM1221)
Length = 311
Score = 86.6 bits (205), Expect = 6e-16
Identities = 61/203 (30%), Positives = 101/203 (49%), Gaps = 6/203 (2%)
Frame = +2
Query: 131 ELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGV 310
E + I TTT +KE+ + + + + + + K+V+DA LK++ GV
Sbjct: 20 EKFGSLQIYTTT----NKEQTIERLKDANVAMTNKVV-IDKDVIDACKNLKLILETATGV 74
Query: 311 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRW-DRALYT 487
+NID++ A +KG+ V NA G + +S + T M V K G+W + ++T
Sbjct: 75 NNIDIEYAKEKGIIVKNAAGYSTMSVVQHTFAFMFAFLNQVPYYDKWSKEGKWCESPIFT 134
Query: 488 G-----SELAGKTLAILGLGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELE 652
+ L+GK I+GLG +G+EVA AFG I + A++ A F +EL+
Sbjct: 135 DYSRILNTLSGKKHGIIGLGTIGKEVAKISKAFGAEIYYYST-SGANKNADF--VHLELK 191
Query: 653 DIWPLADYITLHTPLIXSTRNFI 721
D+ D I++H PL T+N +
Sbjct: 192 DLLKTCDIISIHAPLNEKTKNLL 214
>UniRef50_A7AAD2 Cluster: Putative uncharacterized protein; n=1;
Parabacteroides merdae ATCC 43184|Rep: Putative
uncharacterized protein - Parabacteroides merdae ATCC
43184
Length = 320
Score = 86.6 bits (205), Expect = 6e-16
Identities = 59/202 (29%), Positives = 96/202 (47%), Gaps = 5/202 (2%)
Frame = +2
Query: 131 ELLNAYGIATTTKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGV 310
EL + Y + + EE+L IP +D L V KE++D KLK+V G
Sbjct: 17 ELESKYEVTFPEGRDFTYEEVLEMIPEYDVLCSMFDFPVNKELIDHASKLKMVANYAVGY 76
Query: 311 DNIDVDSAGKKGVGVINAPGANALSACELTCTLMLVLARHVVPASTALK---AGRWDRAL 481
+NIDV +KG+ V N P L LML +AR + L+ G L
Sbjct: 77 NNIDVAYCLEKGITVANTPDPVTAPTANLALGLMLDVARRITECDRKLRREGLGMKVGVL 136
Query: 482 YT-GSELAGKTLAILGLGRVGREVATRMYAFGMNIIGFD-PFVSADQCAQFHCTKMELED 655
G + GKTL I+G+GR+G+ +A R A GM ++ + + ++ + + T + E+
Sbjct: 137 ENLGINVTGKTLGIIGMGRIGKALARRANACGMEVLYHNRRQLYVEEETKLNVTYVSKEE 196
Query: 656 IWPLADYITLHTPLIXSTRNFI 721
+ +D+++L+ P T + I
Sbjct: 197 LLSQSDFVSLNAPYTPETYHII 218
>UniRef50_Q5LT44 Cluster: D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=16; Proteobacteria|Rep:
D-isomer specific 2-hydroxyacid dehydrogenase family
protein - Silicibacter pomeroyi
Length = 330
Score = 86.2 bits (204), Expect = 7e-16
Identities = 56/195 (28%), Positives = 100/195 (51%), Gaps = 7/195 (3%)
Frame = +2
Query: 164 TKAKISKEELLMEIPNHDALVVRSATQVTKEVLDAGV-KLKVVGRAGAGVDNIDVDSAGK 340
T ++ E + DA++ ++ E LD + +++ G G +ID D+
Sbjct: 38 TDTPLTSAEFRSALARFDAILPTVTDKLGAEALDVTAPQTRLLANYGVGYSHIDSDAVRA 97
Query: 341 KGVGVINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWD--RALY-TGSELAGKT 511
G+ V N P + ++ TLML++AR L+AG+W R + GS+++GK
Sbjct: 98 HGITVSNTPDVLSECTADIAMTLMLMVARRAGEGERELRAGQWTGWRPTHLVGSKVSGKV 157
Query: 512 LAILGLGRVGREVATRM-YAFGMNIIGFD-PFVSADQCAQFHCTKME-LEDIWPLADYIT 682
L I+G GR+G+ +A R + FGM I+ + V D ++ T++E L+ + P D+++
Sbjct: 158 LGIVGFGRIGQAMAQRAHHGFGMKILVQNRSAVPQDVLDRYGATQVETLDAMLPQCDFVS 217
Query: 683 LHTPLIXSTRNFINA 727
LH P + R+ IN+
Sbjct: 218 LHCPGGAANRHLINS 232
>UniRef50_Q3S8E5 Cluster: Putative D-isomer specific 2-hydroxyacid
dehydrogenase family protein; n=1; Paracoccus
pantotrophus|Rep: Putative D-isomer specific
2-hydroxyacid dehydrogenase family protein - Paracoccus
pantotrophus (Thiosphaera pantotropha)
Length = 338
Score = 86.2 bits (204), Expect = 7e-16
Identities = 56/185 (30%), Positives = 100/185 (54%), Gaps = 2/185 (1%)
Frame = +2
Query: 179 SKEELLMEIPNHDALV-VRSATQVTKEVLDAGVKLKVVGRAGA-GVDNIDVDSAGKKGVG 352
++ +L+ + DA++ +R T+ + EVL A +L++V G +ID+ + + G+
Sbjct: 36 TETDLIHRLQGFDAVLRIRERTEFSVEVLAALPQLRLVLCTGMRNARSIDLAACDRLGIT 95
Query: 353 VINAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDRALYTGSELAGKTLAILGLG 532
V A A + ELT LM+ L R + +L+AG W + G L GKTL ++GLG
Sbjct: 96 VC-ATDALHQTTVELTVWLMIALMRGLPRECASLRAGGWQVGV--GRSLGGKTLGVVGLG 152
Query: 533 RVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYITLHTPLIXSTR 712
+G VA GM++I + P ++ ++ A+ + E+++ AD +TLH P I +T
Sbjct: 153 NMGIPVAKICKIMGMDVIAWSPNLTQERAAEHGVRAVSKEELFAQADVVTLHMPHINATE 212
Query: 713 NFINA 727
+ ++A
Sbjct: 213 HLVSA 217
>UniRef50_Q0FF66 Cluster: Glycolate reductase; n=2;
Alphaproteobacteria|Rep: Glycolate reductase - alpha
proteobacterium HTCC2255
Length = 319
Score = 86.2 bits (204), Expect = 7e-16
Identities = 51/187 (27%), Positives = 92/187 (49%), Gaps = 4/187 (2%)
Frame = +2
Query: 179 SKEELLMEIPNHDALVVRSATQVTKEVLDA-GVKLKVVGRAGAGVDNIDVDSAGKKGVGV 355
+KEE++ DA+V + + +V+ G +LK++ GVD+ D+ + +K + V
Sbjct: 36 TKEEIISASFEFDAIVPCHSEVFSSDVVSKFGPRLKIIANHSVGVDHCDLAALNEKNILV 95
Query: 356 INAPGANALSACELTCTLMLVLARHVVPASTALKAGRWDR---ALYTGSELAGKTLAILG 526
N P + + E+ LML ARH V +++G W + G +L G + I+G
Sbjct: 96 TNTPDVLSDATAEIAMLLMLGAARHAVLGDEIVRSGNWKNWSPSFMVGKQLTGARIGIIG 155
Query: 527 LGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYITLHTPLIXS 706
+GRVG+ A + F M+I F+ D + +E + ++D+++LH P
Sbjct: 156 MGRVGQAFAKKARGFDMDIHYFNRTKLNDSVSLGASYHDNIESLLKVSDFLSLHCPATPE 215
Query: 707 TRNFINA 727
T+ I+A
Sbjct: 216 TKLLIDA 222
>UniRef50_A6CRV0 Cluster: 2-hydroxyacid dehydrogenase; n=15;
Bacillales|Rep: 2-hydroxyacid dehydrogenase - Bacillus
sp. SG-1
Length = 351
Score = 86.2 bits (204), Expect = 7e-16
Identities = 49/188 (26%), Positives = 87/188 (46%), Gaps = 3/188 (1%)
Frame = +2
Query: 176 ISKEELLMEIPNHDALVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGV 355
+ +E LL + ++ + + +E+ + LKVV G DNID+ +A +K V V
Sbjct: 61 VPREILLEKAGEASGILSMLSDPIDRELFEKSPNLKVVANLAVGFDNIDLKAANEKDVAV 120
Query: 356 INAPGANALSACELTCTLMLVLARHVVPASTALKAGR---WDRALYTGSELAGKTLAILG 526
N P + +LT LM+ AR ++ A ++ G+ W L G+++ KT+ I+G
Sbjct: 121 CNTPDVLTDTTADLTFGLMMAAARRLIEADKYVREGKWKSWSPLLMAGTDIHHKTVGIIG 180
Query: 527 LGRVGREVATRMYAFGMNIIGFDPFVSADQCAQFHCTKMELEDIWPLADYITLHTPLIXS 706
+G +G A R F MNI+ + + LE++ +DY+ PL
Sbjct: 181 MGSIGEAFARRAKGFDMNILYHNRSRKPEAEEVLGAKYASLEELLSQSDYVVCLAPLTPE 240
Query: 707 TRNFINAD 730
T+ + +
Sbjct: 241 TKGLLQKE 248
>UniRef50_A5ZA39 Cluster: Putative uncharacterized protein; n=1;
Eubacterium ventriosum ATCC 27560|Rep: Putative
uncharacterized protein - Eubacterium ventriosum ATCC
27560
Length = 381
Score = 86.2 bits (204), Expect = 7e-16
Identities = 51/177 (28%), Positives = 92/177 (51%), Gaps = 7/177 (3%)
Frame = +2
Query: 221 LVVRSATQVTKEVLDAGVKLKVVGRAGAGVDNIDVDSAGKKGVGVINAPGANALSACELT 400
+V+ + + K +++ G LK++ + GV++I+V A + V N NA +
Sbjct: 102 IVMTHFSPIPKYIIEKGKNLKLILTSRGGVEHINVKEASNHNIPVFNVI-RNAEPVADFA 160
Query: 401 CTLMLVLARHVVPASTALKAGRWDRALYTGSELA---GKTLAILGLGRVGREVATRMYAF 571
LML + R++ + ++ G+W Y ++ G + ++G+G VG +A R+ A
Sbjct: 161 LGLMLDITRNITLSDKFIRNGQWMHEYYNTGQIKLFNGHLVGLVGIGNVGAAIARRLNAL 220
Query: 572 GMNIIGFDPFVSADQCAQ---FHCTKME-LEDIWPLADYITLHTPLIXSTRNFINAD 730
G++II +D FVS ++ AQ K+E +ED++ AD ++LH L T IN D
Sbjct: 221 GVSIIAYDSFVSEERLAQQGLGFIKKVETMEDVFKKADIVSLHLRLTPETEGIINED 277
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 731,207,934
Number of Sequences: 1657284
Number of extensions: 15879789
Number of successful extensions: 82251
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 70433
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 80972
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 59677054775
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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