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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= bmov10g05
         (643 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_UPI00015B411C Cluster: PREDICTED: similar to pseudourid...   159   5e-38
UniRef50_UPI0000D554D8 Cluster: PREDICTED: similar to CG4159-PA;...   154   1e-36
UniRef50_Q9VDK6 Cluster: CG4159-PA; n=4; Diptera|Rep: CG4159-PA ...   151   1e-35
UniRef50_UPI0000DB712C Cluster: PREDICTED: similar to CG4159-PA;...   146   5e-34
UniRef50_Q4T6B0 Cluster: Chromosome undetermined SCAF8839, whole...   118   9e-26
UniRef50_Q9Y606 Cluster: tRNA pseudouridine synthase A; n=29; Eu...   107   2e-22
UniRef50_Q6CC39 Cluster: tRNA pseudouridine synthase 1; n=1; Yar...   104   2e-21
UniRef50_A7RII9 Cluster: Predicted protein; n=3; Eumetazoa|Rep: ...   103   4e-21
UniRef50_A7NVQ8 Cluster: Chromosome chr18 scaffold_1, whole geno...   101   1e-20
UniRef50_Q4P397 Cluster: Putative uncharacterized protein; n=1; ...   101   1e-20
UniRef50_Q54FA0 Cluster: TRNA pseudouridylate synthase; n=1; Dic...   100   3e-20
UniRef50_A2X849 Cluster: Putative uncharacterized protein; n=4; ...    99   1e-19
UniRef50_Q9LN29 Cluster: F14O10.3 protein; n=3; Arabidopsis thal...    97   2e-19
UniRef50_Q9XXN0 Cluster: Putative uncharacterized protein pus-1;...    96   7e-19
UniRef50_Q7S319 Cluster: Putative uncharacterized protein NCU075...    95   1e-18
UniRef50_Q12211 Cluster: tRNA pseudouridine synthase 1; n=7; Sac...    94   2e-18
UniRef50_O94396 Cluster: tRNA pseudouridine synthase 1; n=1; Sch...    94   2e-18
UniRef50_UPI00004993EF Cluster: tRNA pseudouridine synthase; n=1...    93   7e-18
UniRef50_A7TTG9 Cluster: Putative uncharacterized protein; n=1; ...    91   2e-17
UniRef50_Q0U5E9 Cluster: Putative uncharacterized protein; n=1; ...    91   2e-17
UniRef50_Q2H827 Cluster: Putative uncharacterized protein; n=1; ...    90   4e-17
UniRef50_Q3KZ66 Cluster: Pseudouridylate synthase; n=3; Schistos...    89   1e-16
UniRef50_A6SDF5 Cluster: Putative uncharacterized protein; n=2; ...    89   1e-16
UniRef50_P53167 Cluster: tRNA pseudouridine synthase 2; n=2; Sac...    86   6e-16
UniRef50_Q6FJJ6 Cluster: Similar to sp|P53167 Saccharomyces cere...    80   4e-14
UniRef50_Q00ST8 Cluster: TRNA pseudouridylate synthase; n=2; Ost...    79   7e-14
UniRef50_A2QZ58 Cluster: Putative frameshift; n=1; Aspergillus n...    77   5e-13
UniRef50_Q5K777 Cluster: Pseudouridylate synthase, putative; n=2...    74   3e-12
UniRef50_A7NY39 Cluster: Chromosome chr6 scaffold_3, whole genom...    73   6e-12
UniRef50_Q4D3D3 Cluster: Putative uncharacterized protein; n=3; ...    72   1e-11
UniRef50_O22928 Cluster: Putative tRNA pseudouridine synthase; n...    72   1e-11
UniRef50_Q1XD12 Cluster: TRNA pseudouridine synthase; n=1; Pneum...    70   4e-11
UniRef50_O94295 Cluster: tRNA pseudouridine synthase 2; n=1; Sch...    70   4e-11
UniRef50_Q59S63 Cluster: tRNA pseudouridine synthase 1; n=2; Sac...    67   3e-10
UniRef50_Q10LR0 Cluster: TRNA pseudouridine synthase family prot...    65   2e-09
UniRef50_A2XGH5 Cluster: Putative uncharacterized protein; n=1; ...    65   2e-09
UniRef50_Q8SS41 Cluster: Pseudouridylate synthase; n=1; Encephal...    65   2e-09
UniRef50_O74451 Cluster: Pseudouridylate synthase; n=1; Schizosa...    63   5e-09
UniRef50_A5ULI2 Cluster: Pseudouridylate synthase; n=1; Methanob...    63   5e-09
UniRef50_A4S8M4 Cluster: Predicted protein; n=2; Ostreococcus|Re...    61   3e-08
UniRef50_Q54TQ3 Cluster: Putative uncharacterized protein; n=1; ...    60   6e-08
UniRef50_A4RAI8 Cluster: Putative uncharacterized protein; n=1; ...    59   8e-08
UniRef50_A3F4X8 Cluster: TRNA pseudouridine synthase A; n=1; Tae...    58   2e-07
UniRef50_A6RCJ6 Cluster: Putative uncharacterized protein; n=1; ...    58   2e-07
UniRef50_A2SU30 Cluster: Pseudouridylate synthase; n=1; Methanoc...    58   2e-07
UniRef50_O26928 Cluster: tRNA pseudouridine synthase A; n=1; Met...    58   2e-07
UniRef50_Q54LM5 Cluster: Putative uncharacterized protein; n=1; ...    55   2e-06
UniRef50_Q4Q9E9 Cluster: Pseudouridylate synthase-like protein; ...    55   2e-06
UniRef50_A2QE34 Cluster: Catalytic activity: tRNA uridine <=> tR...    54   3e-06
UniRef50_Q2NHB4 Cluster: Pseudouridylate synthase; n=1; Methanos...    54   3e-06
UniRef50_A2DE30 Cluster: tRNA pseudouridine synthase family prot...    54   4e-06
UniRef50_Q22TA6 Cluster: Pseudouridylate synthase; n=1; Tetrahym...    53   5e-06
UniRef50_A7ASP1 Cluster: tRNA pseudouridine synthase, putative; ...    51   2e-05
UniRef50_Q18DQ1 Cluster: Pseudouridylate synthase; n=1; Haloquad...    51   2e-05
UniRef50_A7D6F0 Cluster: tRNA pseudouridine synthase; n=1; Halor...    51   3e-05
UniRef50_Q8U2C1 Cluster: tRNA pseudouridine synthase A; n=4; The...    51   3e-05
UniRef50_A0DFY8 Cluster: Pseudouridylate synthase; n=1; Parameci...    50   4e-05
UniRef50_Q8R601 Cluster: tRNA pseudouridine synthase A; n=3; Fus...    50   4e-05
UniRef50_UPI00015BE519 Cluster: UPI00015BE519 related cluster; n...    50   5e-05
UniRef50_UPI0000DB7775 Cluster: PREDICTED: similar to CG3045-PA;...    50   5e-05
UniRef50_A5PKS2 Cluster: LOC100101318 protein; n=4; Xenopus|Rep:...    50   5e-05
UniRef50_Q5UXW0 Cluster: tRNA pseudouridine synthase A; n=3; Hal...    50   6e-05
UniRef50_Q5NG36 Cluster: tRNA pseudouridine synthase A; n=11; Fr...    50   6e-05
UniRef50_Q4Q3H7 Cluster: Putative uncharacterized protein; n=3; ...    49   8e-05
UniRef50_A2E6F9 Cluster: tRNA pseudouridine synthase family prot...    48   1e-04
UniRef50_A0DJ25 Cluster: Pseudouridylate synthase; n=1; Parameci...    48   2e-04
UniRef50_Q8TU65 Cluster: tRNA pseudouridine synthase A; n=5; Arc...    48   2e-04
UniRef50_A0E7K0 Cluster: Pseudouridylate synthase; n=1; Parameci...    48   3e-04
UniRef50_Q8XLQ0 Cluster: tRNA pseudouridine synthase A 1; n=4; C...    48   3e-04
UniRef50_A2FDS7 Cluster: tRNA pseudouridine synthase family prot...    47   3e-04
UniRef50_Q64EQ0 Cluster: Pseudouridylate synthase; n=1; uncultur...    47   3e-04
UniRef50_P70830 Cluster: tRNA pseudouridine synthase A; n=3; Bor...    47   3e-04
UniRef50_Q9UTB3 Cluster: Pseudouridylate synthase; n=1; Schizosa...    46   6e-04
UniRef50_Q4UIU5 Cluster: Pseudouridylate synthase; n=2; Theileri...    46   8e-04
UniRef50_Q6F1W2 Cluster: tRNA pseudouridine synthase A; n=3; Mol...    46   8e-04
UniRef50_Q8KDR7 Cluster: tRNA pseudouridine synthase A; n=9; Chl...    46   8e-04
UniRef50_Q1FEL6 Cluster: Pseudouridylate synthase; n=1; Clostrid...    45   0.001
UniRef50_A7HCM5 Cluster: tRNA-pseudouridine synthase I; n=2; Ana...    45   0.001
UniRef50_A0LIV1 Cluster: Pseudouridylate synthase; n=1; Syntroph...    45   0.001
UniRef50_Q250I7 Cluster: Pseudouridylate synthase; n=2; Desulfit...    44   0.002
UniRef50_Q0W2P8 Cluster: Pseudouridylate synthase; n=1; uncultur...    44   0.002
UniRef50_Q8DWH1 Cluster: tRNA pseudouridine synthase A; n=42; La...    44   0.002
UniRef50_UPI00015B40A8 Cluster: PREDICTED: similar to pseudourid...    44   0.004
UniRef50_A6DAN4 Cluster: Pseudouridylate synthase; n=1; Caminiba...    44   0.004
UniRef50_Q7QV27 Cluster: GLP_180_17283_16483; n=1; Giardia lambl...    44   0.004
UniRef50_O66953 Cluster: tRNA pseudouridine synthase A; n=1; Aqu...    44   0.004
UniRef50_UPI0000E87E98 Cluster: tRNA pseudouridine synthase A; n...    43   0.007
UniRef50_Q1IRQ4 Cluster: Pseudouridylate synthase; n=2; Acidobac...    43   0.007
UniRef50_A0YB03 Cluster: Pseudouridylate synthase; n=10; Gammapr...    43   0.007
UniRef50_Q4D8T5 Cluster: Pseudouridylate synthase I, putative; n...    43   0.007
UniRef50_Q5L3Q7 Cluster: tRNA pseudouridine synthase A; n=11; Ba...    43   0.007
UniRef50_A7PC02 Cluster: Chromosome chr2 scaffold_11, whole geno...    42   0.010
UniRef50_A5E2I9 Cluster: Pseudouridylate synthase; n=4; Saccharo...    42   0.010
UniRef50_A7I4S8 Cluster: tRNA pseudouridine synthase A; n=1; Can...    42   0.010
UniRef50_Q6DI24 Cluster: Zgc:56653 protein; n=2; Danio rerio|Rep...    42   0.013
UniRef50_Q57WP9 Cluster: Pseudouridylate synthase I, putative; n...    42   0.013
UniRef50_Q6MDE3 Cluster: tRNA pseudouridine synthase A 2; n=1; C...    42   0.013
UniRef50_Q583N7 Cluster: Pseudouridylate synthase; n=1; Trypanos...    42   0.017
UniRef50_Q17C60 Cluster: Pseudouridylate synthase; n=2; Culicida...    42   0.017
UniRef50_Q7RDA0 Cluster: Putative uncharacterized protein PY0552...    41   0.022
UniRef50_Q6C194 Cluster: Pseudouridylate synthase; n=1; Yarrowia...    41   0.022
UniRef50_Q2FT01 Cluster: Pseudouridylate synthase; n=1; Methanos...    41   0.022
UniRef50_Q9PPV4 Cluster: tRNA pseudouridine synthase A; n=1; Ure...    41   0.022
UniRef50_Q8TWZ3 Cluster: tRNA pseudouridine synthase A; n=1; Met...    41   0.022
UniRef50_O28544 Cluster: tRNA pseudouridine synthase A; n=1; Arc...    41   0.022
UniRef50_Q654A2 Cluster: Pseudouridylate synthase; n=3; Oryza sa...    41   0.029
UniRef50_Q5CPW7 Cluster: Pus1p-like type II pseudousynthas TruA;...    41   0.029
UniRef50_A3LX03 Cluster: Pseudouridylate synthase; n=4; Saccharo...    41   0.029
UniRef50_A0B7V0 Cluster: Pseudouridylate synthase; n=1; Methanos...    41   0.029
UniRef50_Q057U4 Cluster: Pseudouridylate synthase; n=1; Buchnera...    40   0.039
UniRef50_Q09524 Cluster: Probable tRNA pseudouridine synthase ta...    40   0.039
UniRef50_A4XKB7 Cluster: Pseudouridylate synthase; n=3; Clostrid...    40   0.051
UniRef50_Q8CWM6 Cluster: tRNA pseudouridine synthase A; n=1; Syn...    40   0.051
UniRef50_P31115 Cluster: tRNA pseudouridine synthase 3; n=5; Sac...    40   0.051
UniRef50_Q820P8 Cluster: tRNA pseudouridine synthase A; n=10; Pr...    40   0.067
UniRef50_Q88XU9 Cluster: tRNA pseudouridine synthase A; n=10; La...    40   0.067
UniRef50_Q3ZZP4 Cluster: Pseudouridylate synthase; n=3; Dehaloco...    39   0.089
UniRef50_Q3Y386 Cluster: Pseudouridylate synthase; n=3; Firmicut...    39   0.089
UniRef50_Q8GUL5 Cluster: Putative uncharacterized protein At5g35...    39   0.089
UniRef50_Q8I0W4 Cluster: TRNA pseudouridine synthase, putative; ...    39   0.089
UniRef50_Q22RZ3 Cluster: TRNA pseudouridine synthase family prot...    39   0.089
UniRef50_A3CXX4 Cluster: Pseudouridylate synthase; n=1; Methanoc...    39   0.089
UniRef50_Q9X1R0 Cluster: tRNA pseudouridine synthase A; n=5; The...    39   0.089
UniRef50_UPI00015653AF Cluster: tRNA-pseudouridine synthase A; n...    39   0.12 
UniRef50_UPI000049A0B0 Cluster: pseudouridine synthase; n=1; Ent...    39   0.12 
UniRef50_Q8IAP2 Cluster: Putative uncharacterized protein PF08_0...    39   0.12 
UniRef50_Q4Q7E9 Cluster: Pseudouridylate synthase; n=5; Trypanos...    39   0.12 
UniRef50_Q64XV0 Cluster: tRNA pseudouridine synthase A; n=16; Ba...    39   0.12 
UniRef50_Q3A9U9 Cluster: Pseudouridylate synthase; n=1; Carboxyd...    38   0.16 
UniRef50_Q08Z59 Cluster: Pseudouridylate synthase; n=2; Cystobac...    38   0.16 
UniRef50_Q7MBB9 Cluster: tRNA pseudouridine synthase A; n=1; Glo...    38   0.16 
UniRef50_Q9BZE2 Cluster: tRNA pseudouridine synthase 3; n=19; Eu...    38   0.16 
UniRef50_A6Q408 Cluster: Pseudouridylate synthase; n=2; unclassi...    38   0.21 
UniRef50_A5KCH3 Cluster: Pseudouridylate synthase 1, putative; n...    38   0.21 
UniRef50_Q8R7Y7 Cluster: tRNA pseudouridine synthase A; n=9; Clo...    38   0.21 
UniRef50_Q7TU07 Cluster: tRNA pseudouridine synthase A; n=1; Pir...    38   0.21 
UniRef50_Q4AHD2 Cluster: TRNA pseudouridine synthase; n=1; Chlor...    38   0.27 
UniRef50_Q11XU3 Cluster: Pseudouridylate synthase; n=1; Cytophag...    38   0.27 
UniRef50_A6TWE8 Cluster: Pseudouridylate synthase; n=4; Clostrid...    37   0.36 
UniRef50_A3I2E1 Cluster: TRNA pseudouridine synthase A; n=1; Alg...    37   0.36 
UniRef50_Q7M9U3 Cluster: tRNA pseudouridine synthase A; n=2; Wol...    37   0.36 
UniRef50_Q72DL8 Cluster: tRNA pseudouridine synthase A; n=2; Des...    37   0.36 
UniRef50_Q890R5 Cluster: tRNA pseudouridine synthase A 2; n=11; ...    37   0.36 
UniRef50_Q6I3T8 Cluster: tRNA pseudouridine synthase A 2; n=12; ...    37   0.36 
UniRef50_Q21IY8 Cluster: Pseudouridylate synthase; n=2; Gammapro...    37   0.48 
UniRef50_Q6G7A2 Cluster: tRNA pseudouridine synthase A; n=16; St...    37   0.48 
UniRef50_A0ZG49 Cluster: Pseudouridylate synthase; n=3; Cyanobac...    36   0.63 
UniRef50_Q9C5K6 Cluster: Pseudouridylate synthase; n=3; core eud...    36   0.63 
UniRef50_Q011R7 Cluster: Exopolyphosphatases and related protein...    36   0.63 
UniRef50_Q7TU31 Cluster: tRNA pseudouridine synthase A; n=5; Pro...    36   0.63 
UniRef50_A6NVS7 Cluster: Pseudouridylate synthase; n=1; Bacteroi...    36   0.83 
UniRef50_Q0UN59 Cluster: Putative uncharacterized protein; n=1; ...    36   0.83 
UniRef50_Q72I65 Cluster: tRNA pseudouridine synthase A; n=3; The...    36   0.83 
UniRef50_Q47HQ7 Cluster: Pseudouridylate synthase; n=1; Dechloro...    36   1.1  
UniRef50_A6BIC3 Cluster: Pseudouridylate synthase; n=1; Dorea lo...    36   1.1  
UniRef50_Q4SEJ2 Cluster: Pseudouridylate synthase; n=3; Tetraodo...    35   1.5  
UniRef50_Q1Q1P7 Cluster: Pseudouridylate synthase; n=1; Candidat...    35   1.5  
UniRef50_A7HKV8 Cluster: tRNA pseudouridine synthase A; n=1; Fer...    35   1.5  
UniRef50_A7SJV8 Cluster: Predicted protein; n=1; Nematostella ve...    35   1.5  
UniRef50_A7ANH8 Cluster: tRNA pseudouridine synthase A family pr...    35   1.5  
UniRef50_Q9KTA4 Cluster: tRNA pseudouridine synthase A; n=29; Ga...    35   1.5  
UniRef50_Q6I4Q2 Cluster: tRNA pseudouridine synthase A 1; n=14; ...    35   1.5  
UniRef50_Q0AUL4 Cluster: Pseudouridylate synthase; n=1; Syntroph...    35   1.9  
UniRef50_A5I338 Cluster: Pseudouridylate synthase; n=7; Clostrid...    35   1.9  
UniRef50_P60351 Cluster: tRNA pseudouridine synthase A; n=2; Can...    35   1.9  
UniRef50_UPI000023D4AE Cluster: hypothetical protein FG10837.1; ...    34   2.5  
UniRef50_Q30RV9 Cluster: Pseudouridylate synthase; n=1; Thiomicr...    34   2.5  
UniRef50_Q8GB97 Cluster: Pseudouridylate synthase; n=2; Clostrid...    34   2.5  
UniRef50_Q1FLK6 Cluster: Pseudouridylate synthase; n=1; Clostrid...    34   2.5  
UniRef50_A7I1Z3 Cluster: tRNA pseudouridine synthase A; n=1; Cam...    34   2.5  
UniRef50_A0RNY9 Cluster: Pseudouridylate synthase; n=2; Campylob...    34   2.5  
UniRef50_A5E5W9 Cluster: Putative uncharacterized protein; n=1; ...    34   2.5  
UniRef50_Q6MEE7 Cluster: tRNA pseudouridine synthase A 1; n=1; C...    34   2.5  
UniRef50_UPI0000E48924 Cluster: PREDICTED: similar to FKSG32, pa...    34   3.4  
UniRef50_Q4ALX6 Cluster: Pseudouridylate synthase; n=1; Chlorobi...    34   3.4  
UniRef50_Q5CV63 Cluster: Pseudouridylate synthase; n=2; Cryptosp...    34   3.4  
UniRef50_A0CKA3 Cluster: Chromosome undetermined scaffold_2, who...    34   3.4  
UniRef50_Q30XU3 Cluster: Pseudouridylate synthase; n=2; Desulfov...    33   4.4  
UniRef50_A3ZQX0 Cluster: Pseudouridylate synthase; n=2; Bacteria...    33   4.4  
UniRef50_Q8ZXR6 Cluster: tRNA pseudouridine synthase A; n=4; Pyr...    33   4.4  
UniRef50_Q26G59 Cluster: Pseudouridylate synthase; n=5; Flavobac...    33   5.9  
UniRef50_Q1NSM9 Cluster: Putative uncharacterized protein; n=1; ...    33   5.9  
UniRef50_Q7QX52 Cluster: Pseudouridylate synthase; n=1; Giardia ...    33   5.9  
UniRef50_Q4N208 Cluster: Putative uncharacterized protein; n=1; ...    33   5.9  
UniRef50_Q231M3 Cluster: Tubulin-tyrosine ligase family protein;...    33   5.9  
UniRef50_A5E087 Cluster: Protein POS5; n=2; Saccharomycetales|Re...    33   5.9  
UniRef50_P56144 Cluster: tRNA pseudouridine synthase A; n=4; Hel...    33   5.9  
UniRef50_Q0F2X2 Cluster: Pseudouridylate synthase; n=1; Mariprof...    33   7.7  
UniRef50_A7C1F2 Cluster: tRNA pseudouridine synthase A; n=1; Beg...    33   7.7  
UniRef50_A2U011 Cluster: Pseudouridylate synthase; n=2; Polariba...    33   7.7  
UniRef50_Q54I97 Cluster: Pseudouridylate synthase; n=1; Dictyost...    33   7.7  
UniRef50_A7RKL3 Cluster: Predicted protein; n=2; Nematostella ve...    33   7.7  
UniRef50_Q96KH5 Cluster: HEIL2; n=1; Homo sapiens|Rep: HEIL2 - H...    33   7.7  
UniRef50_Q8D2P5 Cluster: tRNA pseudouridine synthase A; n=1; Wig...    33   7.7  
UniRef50_P47428 Cluster: tRNA pseudouridine synthase A; n=3; Myc...    33   7.7  
UniRef50_Q8CY46 Cluster: tRNA pseudouridine synthase A; n=3; Bif...    33   7.7  

>UniRef50_UPI00015B411C Cluster: PREDICTED: similar to
           pseudouridylate synthase; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to pseudouridylate synthase - Nasonia
           vitripennis
          Length = 437

 Score =  159 bits (386), Expect = 5e-38
 Identities = 76/129 (58%), Positives = 92/129 (71%)
 Frame = +2

Query: 257 KPYERIKRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQ 436
           +P+ RIKRK  AM+LGY G  YYGMQRNPG  TI             IT E FE  QN  
Sbjct: 64  QPFIRIKRKNYAMMLGYCGKNYYGMQRNPGFNTIEEELIKAMLKADLITSEAFETIQNIN 123

Query: 437 FQRSSRTDKGVSAAEQVVSLKLPLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNAR 616
           FQR++RTDKGVSA  QVVSLKLP + + + IN+ LPE I+VFA+KRVT  FNSKS+C+AR
Sbjct: 124 FQRAARTDKGVSAVRQVVSLKLPEDPSKDSINETLPEDIRVFAIKRVTKGFNSKSQCDAR 183

Query: 617 SYSYTLPTY 643
           +YSYT+PT+
Sbjct: 184 TYSYTMPTF 192


>UniRef50_UPI0000D554D8 Cluster: PREDICTED: similar to CG4159-PA;
           n=1; Tribolium castaneum|Rep: PREDICTED: similar to
           CG4159-PA - Tribolium castaneum
          Length = 588

 Score =  154 bits (374), Expect = 1e-36
 Identities = 74/137 (54%), Positives = 98/137 (71%)
 Frame = +2

Query: 230 ETKPPGEIKKPYERIKRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQE 409
           ET+  GE+    E+IKR+K A+LLGYSG  YYGMQRNP   TI            YI++E
Sbjct: 241 ETEVTGEL---IEKIKRRKFAVLLGYSGTNYYGMQRNPNTPTIEEEFFKALYKNNYISEE 297

Query: 410 DFENAQNAQFQRSSRTDKGVSAAEQVVSLKLPLEVNVEEINKRLPETIKVFAVKRVTNRF 589
           +F   Q  QFQR++RTDKGVSAA QVVSLKL  ++++ +IN++LPE I+VF ++RVT  F
Sbjct: 298 NFTQVQTMQFQRAARTDKGVSAARQVVSLKLREDIDISKINEQLPEVIRVFGIRRVTKGF 357

Query: 590 NSKSKCNARSYSYTLPT 640
           NSK +C++RSY+Y LPT
Sbjct: 358 NSKVQCDSRSYTYLLPT 374


>UniRef50_Q9VDK6 Cluster: CG4159-PA; n=4; Diptera|Rep: CG4159-PA -
           Drosophila melanogaster (Fruit fly)
          Length = 410

 Score =  151 bits (366), Expect = 1e-35
 Identities = 71/127 (55%), Positives = 92/127 (72%)
 Frame = +2

Query: 260 PYERIKRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQF 439
           P +RIKRKK A+LL Y G  YYGMQRNPG+QTI            +IT++ FE  Q + F
Sbjct: 63  PADRIKRKKSAILLSYCGANYYGMQRNPGMQTIEEELFKAMLKHKWITEDSFEQIQISCF 122

Query: 440 QRSSRTDKGVSAAEQVVSLKLPLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARS 619
           QR++RTDKGVSAA QV S+KLP E+++E  N  LP+ I++F V+RVT  FN+K +CNAR+
Sbjct: 123 QRAARTDKGVSAARQVCSVKLPEELDLEAFNADLPQQIRLFGVERVTKGFNAKDQCNART 182

Query: 620 YSYTLPT 640
           Y+YTLPT
Sbjct: 183 YTYTLPT 189


>UniRef50_UPI0000DB712C Cluster: PREDICTED: similar to CG4159-PA;
           n=1; Apis mellifera|Rep: PREDICTED: similar to CG4159-PA
           - Apis mellifera
          Length = 366

 Score =  146 bits (353), Expect = 5e-34
 Identities = 75/164 (45%), Positives = 101/164 (61%)
 Frame = +2

Query: 152 EENKSIDIVPNKLLTRYNKRRAHRDWETKPPGEIKKPYERIKRKKMAMLLGYSGVEYYGM 331
           E NK I+ V  +   R     +       P  +I +    IK+KK  M+LGY G  Y GM
Sbjct: 4   ETNKQIEDVVEETNKRQIIDESSEIVAKAPKLDIIEKKNNIKKKKFVMVLGYLGKNYSGM 63

Query: 332 QRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTDKGVSAAEQVVSLKLPLE 511
           Q N G++TI            +IT+ +FE+ +  +FQR++RTDKGVSA  Q+VSL+LP  
Sbjct: 64  QINRGIKTIEGSLLSALLKADFITKNEFEDLKEIKFQRAARTDKGVSAVRQIVSLQLPNH 123

Query: 512 VNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYSYTLPTY 643
           VN E+INK LP+ IKVF +KRVT  FNSK+KC+AR+Y Y LPT+
Sbjct: 124 VNKEDINKHLPKDIKVFDIKRVTRNFNSKNKCDARTYRYVLPTF 167


>UniRef50_Q4T6B0 Cluster: Chromosome undetermined SCAF8839, whole
           genome shotgun sequence; n=1; Tetraodon
           nigroviridis|Rep: Chromosome undetermined SCAF8839,
           whole genome shotgun sequence - Tetraodon nigroviridis
           (Green puffer)
          Length = 375

 Score =  118 bits (285), Expect = 9e-26
 Identities = 66/128 (51%), Positives = 83/128 (64%), Gaps = 4/128 (3%)
 Frame = +2

Query: 269 RIKRKKMAMLLGYSGVEYYGMQRNPG---VQTIXXXXXXXXXXXXYITQEDFENAQNAQF 439
           R  +KK+A+LL YSG  YYGMQRNPG    +TI             I +   E+ +   F
Sbjct: 71  RYPKKKVALLLAYSGKGYYGMQRNPGSSEFRTIEDDLVAALVKSGCIPENHAEDMKKMSF 130

Query: 440 QRSSRTDKGVSAAEQVVSLKLPLEVNV-EEINKRLPETIKVFAVKRVTNRFNSKSKCNAR 616
           QR +RTDKGVSAA QVVSLKL L  ++ E+IN+ LP  I+V  VKRVT  FNSK+ C+AR
Sbjct: 131 QRCARTDKGVSAAGQVVSLKLWLIDDLAEKINQHLPPQIRVLGVKRVTQGFNSKNNCDAR 190

Query: 617 SYSYTLPT 640
           +Y+Y LPT
Sbjct: 191 TYAYMLPT 198


>UniRef50_Q9Y606 Cluster: tRNA pseudouridine synthase A; n=29;
           Euteleostomi|Rep: tRNA pseudouridine synthase A - Homo
           sapiens (Human)
          Length = 427

 Score =  107 bits (258), Expect = 2e-22
 Identities = 58/130 (44%), Positives = 82/130 (63%), Gaps = 4/130 (3%)
 Frame = +2

Query: 266 ERIKRKKMAMLLGYSGVEYYGMQRNPG---VQTIXXXXXXXXXXXXYITQEDFENAQNAQ 436
           E+  ++K+ +L+ YSG  Y+GMQRN G    +TI             I +   E+ +   
Sbjct: 79  EKPPKRKIVLLMAYSGKGYHGMQRNVGSSQFKTIEDDLVSALVRSGCIPENHGEDMRKMS 138

Query: 437 FQRSSRTDKGVSAAEQVVSLKLPLEVNV-EEINKRLPETIKVFAVKRVTNRFNSKSKCNA 613
           FQR +RTDKGVSAA QVVSLK+ L  ++ E+IN  LP  I++  +KRVT  FNSK++C+A
Sbjct: 139 FQRCARTDKGVSAAGQVVSLKVWLIDDILEKINSHLPSHIRILGLKRVTGGFNSKNRCDA 198

Query: 614 RSYSYTLPTY 643
           R+Y Y LPT+
Sbjct: 199 RTYCYLLPTF 208


>UniRef50_Q6CC39 Cluster: tRNA pseudouridine synthase 1; n=1;
           Yarrowia lipolytica|Rep: tRNA pseudouridine synthase 1 -
           Yarrowia lipolytica (Candida lipolytica)
          Length = 528

 Score =  104 bits (249), Expect = 2e-21
 Identities = 54/148 (36%), Positives = 82/148 (55%), Gaps = 2/148 (1%)
 Frame = +2

Query: 206 KRRAHRDWETKPPGEIKKPYERIKRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXX 385
           K+   RD   K  G +     R  ++K+A ++GY G  Y+GMQ NP  +TI         
Sbjct: 60  KQGEGRDTRRKTDGPLVADEVRQPKRKVACMIGYCGTGYHGMQLNPPQKTIEGDIFQAFV 119

Query: 386 XXXYITQEDFENAQNAQFQRSSRTDKGVSAAEQVVSLKLPLEVN--VEEINKRLPETIKV 559
               I+Q + ++ + + F R++RTDKGV AA  V+SLK+ +E    VE+IN  LPE ++V
Sbjct: 120 KAGAISQNNADDPKKSAFMRAARTDKGVHAAGNVISLKMIIEDENIVEKINSHLPEQLRV 179

Query: 560 FAVKRVTNRFNSKSKCNARSYSYTLPTY 643
           + V R    F  +  C++R Y Y +PTY
Sbjct: 180 WGVSRTNKAFECRKLCSSRVYEYLMPTY 207


>UniRef50_A7RII9 Cluster: Predicted protein; n=3; Eumetazoa|Rep:
           Predicted protein - Nematostella vectensis
          Length = 300

 Score =  103 bits (247), Expect = 4e-21
 Identities = 55/123 (44%), Positives = 72/123 (58%), Gaps = 1/123 (0%)
 Frame = +2

Query: 278 RKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRT 457
           +KK A+L+ Y GV Y GMQ NPGV+TI             IT +  E      FQR +RT
Sbjct: 1   KKKCALLISYCGVGYAGMQINPGVRTIEEQLINALHQAEVITDDAKECLGKMSFQRCART 60

Query: 458 DKGVSAAEQVVSLKL-PLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYSYTL 634
           DKGVSAA QVVSLK+  L   + +IN  LP  I++F + + T  F+ K  C+AR+Y Y  
Sbjct: 61  DKGVSAARQVVSLKISALSSLLPKINSFLPPEIRIFGMIKTTKAFDCKQNCSARTYEYLT 120

Query: 635 PTY 643
           PT+
Sbjct: 121 PTF 123


>UniRef50_A7NVQ8 Cluster: Chromosome chr18 scaffold_1, whole genome
           shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
           chr18 scaffold_1, whole genome shotgun sequence - Vitis
           vinifera (Grape)
          Length = 378

 Score =  101 bits (243), Expect = 1e-20
 Identities = 54/132 (40%), Positives = 76/132 (57%), Gaps = 2/132 (1%)
 Frame = +2

Query: 254 KKPYERIKRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNA 433
           KKP  R KR+K+A+   Y GV Y GMQ+NPG +TI             + ++D  + +  
Sbjct: 32  KKP--RYKRRKIAIFFAYCGVGYQGMQKNPGAKTIEGDLEEALFFSGAVPEQDRGHPKRF 89

Query: 434 QFQRSSRTDKGVSAAEQVVSLKLPLEVN--VEEINKRLPETIKVFAVKRVTNRFNSKSKC 607
            + RS+RTDKGVSA  QVVS +  ++    VE +N  LP  I++F  KRVT  FN+K  C
Sbjct: 90  DWARSARTDKGVSAVGQVVSGRFYIDPPGLVERLNSNLPPQIRIFGFKRVTASFNAKKFC 149

Query: 608 NARSYSYTLPTY 643
           + R Y Y +P +
Sbjct: 150 DRRRYVYLIPVF 161


>UniRef50_Q4P397 Cluster: Putative uncharacterized protein; n=1;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 615

 Score =  101 bits (242), Expect = 1e-20
 Identities = 55/159 (34%), Positives = 88/159 (55%), Gaps = 10/159 (6%)
 Frame = +2

Query: 197 RYNKRRAHRDWETKPPG--EIKKPYERIKRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXX 370
           R ++R   R  + + P   E     +R+ ++K+A+  GY G+ Y G+Q NPGV+TI    
Sbjct: 91  RRDRRGTGRAQDNESPSTCEASASTDRLPKRKVAVKFGYCGIGYSGLQINPGVKTIEGDI 150

Query: 371 XXXXXXXXYITQEDFENAQNAQFQRSSRTDKGVSAAEQVVSLKL--------PLEVNVEE 526
                    ++ ++  N      QR++RTD+GV AA  ++SLKL        P E  V++
Sbjct: 151 FDAFCTAGAVSSDNAVNPNKVGLQRAARTDRGVHAAGNLLSLKLILQPQGLKPGETLVDK 210

Query: 527 INKRLPETIKVFAVKRVTNRFNSKSKCNARSYSYTLPTY 643
           +N+ LP  I+++ V RV N FN++  C++R Y Y LPTY
Sbjct: 211 VNELLPPFIRIWGVTRVQNGFNARQSCDSRMYEYLLPTY 249


>UniRef50_Q54FA0 Cluster: TRNA pseudouridylate synthase; n=1;
           Dictyostelium discoideum AX4|Rep: TRNA pseudouridylate
           synthase - Dictyostelium discoideum AX4
          Length = 596

 Score =  100 bits (240), Expect = 3e-20
 Identities = 63/188 (33%), Positives = 96/188 (51%), Gaps = 16/188 (8%)
 Frame = +2

Query: 128 EAADVTKDEENKSIDIVPNKLLTRYNKRRAHRDWETKPP-----------GEIKKPYERI 274
           EA +   D+  K  +       T  NKR+ ++    +PP            + K   +  
Sbjct: 78  EADEDELDKFEKESESTSTTTTTTENKRKPNQPPPVRPPKLSKEELIELQNKTKITTDES 137

Query: 275 KRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSR 454
           ++KK+A++LGYSG  Y GMQ+NPG++T+             I+ ++    Q   + R +R
Sbjct: 138 RKKKVAIILGYSGTNYAGMQKNPGLKTVEEELEHALFRTGGISPDNMYYQQKVDWIRCAR 197

Query: 455 TDKGVSAAEQVVSLKLPL-----EVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARS 619
           TDKGVSA   VVSLK+ +     E     +NK LP+ I VF + RV N F++K+  +ARS
Sbjct: 198 TDKGVSAIRNVVSLKMEMGPPDFEGMKIALNKELPKDITVFHIMRVNNSFHAKNAVDARS 257

Query: 620 YSYTLPTY 643
           Y Y  PT+
Sbjct: 258 YIYVTPTH 265


>UniRef50_A2X849 Cluster: Putative uncharacterized protein; n=4;
           Magnoliophyta|Rep: Putative uncharacterized protein -
           Oryza sativa subsp. indica (Rice)
          Length = 588

 Score = 98.7 bits (235), Expect = 1e-19
 Identities = 52/127 (40%), Positives = 73/127 (57%), Gaps = 2/127 (1%)
 Frame = +2

Query: 269 RIKRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRS 448
           R KR+K+A+LLGY G  Y GMQ+NPG +TI             + + D    +   + R+
Sbjct: 45  RYKRRKVAILLGYCGAGYQGMQKNPGARTIEGDLEEALYRAGAVPEADRAAPRRYDWARA 104

Query: 449 SRTDKGVSAAEQVVSLKLPLE--VNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSY 622
           +RTDKGVSAA QVVS +  ++  V  + +N +L   I+ F   RVTN FN+K  C+ R Y
Sbjct: 105 ARTDKGVSAAAQVVSGRFYVDPPVFTDRLNAQLAPQIRAFGYVRVTNSFNAKKFCDRRRY 164

Query: 623 SYTLPTY 643
            Y LP +
Sbjct: 165 VYLLPVF 171


>UniRef50_Q9LN29 Cluster: F14O10.3 protein; n=3; Arabidopsis
           thaliana|Rep: F14O10.3 protein - Arabidopsis thaliana
           (Mouse-ear cress)
          Length = 549

 Score = 97.5 bits (232), Expect = 2e-19
 Identities = 49/127 (38%), Positives = 74/127 (58%), Gaps = 2/127 (1%)
 Frame = +2

Query: 269 RIKRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRS 448
           + +R+K+A++  + GV Y GMQ+NPG +TI             +   D    +N ++ RS
Sbjct: 54  KYRRRKVAIVFAFCGVGYQGMQKNPGAKTIEGELEEALFHAGAVPDADRNKPRNYEWARS 113

Query: 449 SRTDKGVSAAEQVVSLKLPLEVN--VEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSY 622
           +RTDKGVSA  QVVS +  ++    VE +N +LP+ I+VF  KRV   F+SK  C+ R Y
Sbjct: 114 ARTDKGVSAVGQVVSGRFYVDPPGFVERLNSKLPDQIRVFGYKRVAPSFSSKKFCDRRRY 173

Query: 623 SYTLPTY 643
            Y +P +
Sbjct: 174 VYLIPVF 180


>UniRef50_Q9XXN0 Cluster: Putative uncharacterized protein pus-1;
           n=2; Caenorhabditis|Rep: Putative uncharacterized
           protein pus-1 - Caenorhabditis elegans
          Length = 415

 Score = 95.9 bits (228), Expect = 7e-19
 Identities = 54/138 (39%), Positives = 78/138 (56%), Gaps = 6/138 (4%)
 Frame = +2

Query: 248 EIKKPYERIKRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQ 427
           E KKP  R+K+ K AMLLGY G +YYGMQ    + TI            +IT    E   
Sbjct: 24  EPKKP--RVKQAKYAMLLGYQGKKYYGMQLQKDLPTIESKLLEAMETAGWITTAQKEKPF 81

Query: 428 NAQFQRSSRTDKGVSAAEQVVSLKLPLE------VNVEEINKRLPETIKVFAVKRVTNRF 589
           +  FQR++RTD+ VSAA Q+  ++LP +           +N  LP  I+VF ++R TN F
Sbjct: 82  DFFFQRAARTDRAVSAARQMCGMQLPRDDAKYQAEGAGILNNILPADIRVFGMRRTTNFF 141

Query: 590 NSKSKCNARSYSYTLPTY 643
           + + +C+ R+YSYT P++
Sbjct: 142 HPQKQCDHRTYSYTCPSF 159


>UniRef50_Q7S319 Cluster: Putative uncharacterized protein
           NCU07528.1; n=2; Sordariomycetes|Rep: Putative
           uncharacterized protein NCU07528.1 - Neurospora crassa
          Length = 625

 Score = 95.5 bits (227), Expect = 1e-18
 Identities = 49/128 (38%), Positives = 79/128 (61%), Gaps = 2/128 (1%)
 Frame = +2

Query: 266 ERIKRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQR 445
           ER  ++K+A+L+GY+G  Y+G+Q N   +TI             I++ + ++ + +   R
Sbjct: 116 ERRPKRKVAVLIGYAGTGYHGIQINHKEKTIEGDLFAAFVKAGAISKANADDPKKSSLVR 175

Query: 446 SSRTDKGVSAAEQVVSLKLPLEVN--VEEINKRLPETIKVFAVKRVTNRFNSKSKCNARS 619
            +RTDKGV AA  V+SLKL +E    V++IN  LP+ IKV+ ++RVTN F+    C++R 
Sbjct: 176 CARTDKGVHAAANVLSLKLIVEDEDIVDKINSHLPDQIKVWGIQRVTNGFSCYQACDSRW 235

Query: 620 YSYTLPTY 643
           Y Y +P+Y
Sbjct: 236 YEYLMPSY 243


>UniRef50_Q12211 Cluster: tRNA pseudouridine synthase 1; n=7;
           Saccharomycetales|Rep: tRNA pseudouridine synthase 1 -
           Saccharomyces cerevisiae (Baker's yeast)
          Length = 544

 Score = 94.3 bits (224), Expect = 2e-18
 Identities = 46/127 (36%), Positives = 78/127 (61%), Gaps = 2/127 (1%)
 Frame = +2

Query: 269 RIKRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRS 448
           R+ ++K+A+++GY G  Y+GMQ NP   TI             I++++  + +   F R+
Sbjct: 71  RLPKRKVAVMVGYCGTGYHGMQYNPPNPTIESALFKAFVEAGAISKDNSNDLKKNGFMRA 130

Query: 449 SRTDKGVSAAEQVVSLKLPLEVN--VEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSY 622
           +RTDKGV A   ++SLK+ +E     ++IN++LPE I+V+ ++RV   F+ +  C++R Y
Sbjct: 131 ARTDKGVHAGGNLISLKMIIEDPDIKQKINEKLPEGIRVWDIERVNKAFDCRKMCSSRWY 190

Query: 623 SYTLPTY 643
            Y LPTY
Sbjct: 191 EYLLPTY 197


>UniRef50_O94396 Cluster: tRNA pseudouridine synthase 1; n=1;
           Schizosaccharomyces pombe|Rep: tRNA pseudouridine
           synthase 1 - Schizosaccharomyces pombe (Fission yeast)
          Length = 534

 Score = 94.3 bits (224), Expect = 2e-18
 Identities = 47/128 (36%), Positives = 76/128 (59%), Gaps = 2/128 (1%)
 Frame = +2

Query: 266 ERIKRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQR 445
           E+  ++K+A L+GY G  Y+GMQ NP  +TI             ++  + ++ +     R
Sbjct: 39  EKKPKRKVACLVGYCGSGYHGMQLNPPSKTIEGDLFDAFVKAGAVSSYNADDPKKVALAR 98

Query: 446 SSRTDKGVSAAEQVVSLKLPLEVN--VEEINKRLPETIKVFAVKRVTNRFNSKSKCNARS 619
           ++RTDKGV AA  V+SLKL +E    +E++N+ LP +I+++ V R  N FN ++ C +R 
Sbjct: 99  AARTDKGVHAAGNVISLKLIMEDEKLIEKVNEHLPPSIRLWDVIRTINSFNPRTYCESRI 158

Query: 620 YSYTLPTY 643
           Y Y +PTY
Sbjct: 159 YEYMVPTY 166


>UniRef50_UPI00004993EF Cluster: tRNA pseudouridine synthase; n=1;
           Entamoeba histolytica HM-1:IMSS|Rep: tRNA pseudouridine
           synthase - Entamoeba histolytica HM-1:IMSS
          Length = 401

 Score = 92.7 bits (220), Expect = 7e-18
 Identities = 52/137 (37%), Positives = 83/137 (60%), Gaps = 2/137 (1%)
 Frame = +2

Query: 239 PPGEIKKPYERIKRKKMAMLLGYSGVEYYG-MQRNPGVQTIXXXXXXXXXXXXYITQEDF 415
           P  E KK  ERIK+ K+A++  Y G  Y+G M  N   +TI             I++++ 
Sbjct: 29  PKEEEKK--ERIKKFKVAVIFSYVGRGYFGLMYLNNNPKTIEGEIENAMYKAKCISEDNK 86

Query: 416 ENAQNAQFQRSSRTDKGVSAAEQVVSLKLPLEVN-VEEINKRLPETIKVFAVKRVTNRFN 592
            + +   + R +RTDKGVSAA  ++SLK+ L+ N +E IN  LPETI++  V +V++ FN
Sbjct: 87  HDLKKVGWSRCARTDKGVSAANNLISLKMGLDGNYIERINSFLPETIRIQDVVKVSHSFN 146

Query: 593 SKSKCNARSYSYTLPTY 643
           +K++ ++R+Y Y  P+Y
Sbjct: 147 AKTRVDSRTYEYIFPSY 163


>UniRef50_A7TTG9 Cluster: Putative uncharacterized protein; n=1;
           Vanderwaltozyma polyspora DSM 70294|Rep: Putative
           uncharacterized protein - Vanderwaltozyma polyspora DSM
           70294
          Length = 562

 Score = 91.5 bits (217), Expect = 2e-17
 Identities = 46/128 (35%), Positives = 75/128 (58%), Gaps = 2/128 (1%)
 Frame = +2

Query: 266 ERIKRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQR 445
           +R+ ++K+A+++GY G  Y+GMQ NP   TI             I++ +  + +   F R
Sbjct: 72  KRLPKRKVAVMVGYCGTGYHGMQYNPPNPTIEDALFKAFVQAGAISKANSNDLKKNGFMR 131

Query: 446 SSRTDKGVSAAEQVVSLKLPLE--VNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARS 619
           ++RTDKGV A   ++SLK+ +E     ++IN+ LP  IKV+ ++RV   F+ +  C +R 
Sbjct: 132 AARTDKGVHAGGNLISLKMIIEDPEIKQKINEELPNGIKVWNIERVNKAFDCRKMCGSRW 191

Query: 620 YSYTLPTY 643
           Y Y LPTY
Sbjct: 192 YEYLLPTY 199


>UniRef50_Q0U5E9 Cluster: Putative uncharacterized protein; n=1;
           Phaeosphaeria nodorum|Rep: Putative uncharacterized
           protein - Phaeosphaeria nodorum (Septoria nodorum)
          Length = 621

 Score = 91.1 bits (216), Expect = 2e-17
 Identities = 49/136 (36%), Positives = 78/136 (57%), Gaps = 2/136 (1%)
 Frame = +2

Query: 242 PGEIKKPYERIKRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFEN 421
           P E  +  ER  ++K+A+++GYSG  Y GMQ +   +TI             I++ + ++
Sbjct: 92  PAEEVEAEERRPKRKVAVMIGYSGTGYKGMQIDNKQKTIEGDLFTAFVAAGAISKANADD 151

Query: 422 AQNAQFQRSSRTDKGVSAAEQVVSLKLPLEVN--VEEINKRLPETIKVFAVKRVTNRFNS 595
            + +   R +RTDKGV AA  V+SLKL +E    VE+IN  L E I+V+ ++R T  F+ 
Sbjct: 152 PKKSSLVRCARTDKGVHAAGNVISLKLIIEEEDIVEKINSHLSEQIRVWGIQRTTGSFSC 211

Query: 596 KSKCNARSYSYTLPTY 643
              C++R Y Y +PT+
Sbjct: 212 YQACDSRWYEYLIPTH 227


>UniRef50_Q2H827 Cluster: Putative uncharacterized protein; n=1;
           Chaetomium globosum|Rep: Putative uncharacterized
           protein - Chaetomium globosum (Soil fungus)
          Length = 584

 Score = 90.2 bits (214), Expect = 4e-17
 Identities = 46/128 (35%), Positives = 77/128 (60%), Gaps = 2/128 (1%)
 Frame = +2

Query: 266 ERIKRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQR 445
           ER  ++K+A+L+GY+G  Y+G+Q N   +TI             I++ + ++ + +   R
Sbjct: 103 ERRPKRKVAVLIGYAGTGYHGIQINHKEKTIEGDLFSAFVAAGAISKANADDPKKSSLVR 162

Query: 446 SSRTDKGVSAAEQVVSLKLPLEVN--VEEINKRLPETIKVFAVKRVTNRFNSKSKCNARS 619
            +RTDKGV AA  V+SLKL +E    V +IN+ LPE I+++ + R +N F++   C +R 
Sbjct: 163 CARTDKGVHAAGNVLSLKLIVEDEDIVTKINEHLPEQIRIWGIHRTSNGFSAYQACESRW 222

Query: 620 YSYTLPTY 643
           Y Y +P+Y
Sbjct: 223 YEYLMPSY 230


>UniRef50_Q3KZ66 Cluster: Pseudouridylate synthase; n=3; Schistosoma
           japonicum|Rep: Pseudouridylate synthase - Schistosoma
           japonicum (Blood fluke)
          Length = 334

 Score = 88.6 bits (210), Expect = 1e-16
 Identities = 49/124 (39%), Positives = 68/124 (54%), Gaps = 1/124 (0%)
 Frame = +2

Query: 275 KRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSR 454
           KR+  A+L+ YSG  YYGMQR P   TI             +     E  +   FQR+S+
Sbjct: 45  KRRNNAILMMYSGWGYYGMQRGPIYPTIEGELSKALFTCGQLVNVTSEEHKKVNFQRASK 104

Query: 455 TDKGVSAAEQVVSLKLPLEVNV-EEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYSYT 631
           TDK VSA  QV SLKL  + ++  ++N  LP+ I++  + RVT  F+S + C  R Y Y 
Sbjct: 105 TDKYVSALGQVCSLKLYDDADLLNKLNTALPQDIRILDIIRVTRSFSSYNSCTHRVYDYL 164

Query: 632 LPTY 643
           LPT+
Sbjct: 165 LPTF 168


>UniRef50_A6SDF5 Cluster: Putative uncharacterized protein; n=2;
           Sclerotiniaceae|Rep: Putative uncharacterized protein -
           Botryotinia fuckeliana B05.10
          Length = 631

 Score = 88.6 bits (210), Expect = 1e-16
 Identities = 49/134 (36%), Positives = 76/134 (56%), Gaps = 2/134 (1%)
 Frame = +2

Query: 248 EIKKPYERIKRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQ 427
           E++KP     + K+A+++GY+G  Y G+Q N   +TI             I++ +  + +
Sbjct: 92  EVRKP-----KHKVAVMIGYAGTGYKGLQINTKEKTIEGDMFKAFVAAGAISKANANDPK 146

Query: 428 NAQFQRSSRTDKGVSAAEQVVSLKLPLE--VNVEEINKRLPETIKVFAVKRVTNRFNSKS 601
            +   R +RTDKGV AA  V+SLKL +E    VE IN  LP+ I+V+ ++R T  FN   
Sbjct: 147 KSALIRCARTDKGVHAAGNVLSLKLIIEDPKVVENINSHLPDQIRVWGIERTTGSFNCYQ 206

Query: 602 KCNARSYSYTLPTY 643
            C++R Y Y +PTY
Sbjct: 207 MCDSRWYEYLIPTY 220


>UniRef50_P53167 Cluster: tRNA pseudouridine synthase 2; n=2;
           Saccharomyces cerevisiae|Rep: tRNA pseudouridine
           synthase 2 - Saccharomyces cerevisiae (Baker's yeast)
          Length = 370

 Score = 86.2 bits (204), Expect = 6e-16
 Identities = 45/118 (38%), Positives = 68/118 (57%), Gaps = 1/118 (0%)
 Frame = +2

Query: 293 MLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTDKGVS 472
           MLLGY G  YYGMQ NP  +TI             I++E+    +   F  ++RTDKGV 
Sbjct: 1   MLLGYCGSGYYGMQYNPPHKTIEGEILTKLFDVGAISEENSLAPKKNSFMAAARTDKGVH 60

Query: 473 AAEQVVSLKLPL-EVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYSYTLPTY 643
           A   ++SLK+ L E  V ++N  LP  I+V+ ++ V  +FN++S C++R Y Y +P +
Sbjct: 61  AMLNLLSLKITLREDTVAKLNAALPPEIRVWGIQPVNKKFNARSACDSRWYQYLIPEF 118


>UniRef50_Q6FJJ6 Cluster: Similar to sp|P53167 Saccharomyces
           cerevisiae YGL063w PUS2 pseudouridine synthase 2; n=1;
           Candida glabrata|Rep: Similar to sp|P53167 Saccharomyces
           cerevisiae YGL063w PUS2 pseudouridine synthase 2 -
           Candida glabrata (Yeast) (Torulopsis glabrata)
          Length = 317

 Score = 80.2 bits (189), Expect = 4e-14
 Identities = 43/124 (34%), Positives = 68/124 (54%), Gaps = 5/124 (4%)
 Frame = +2

Query: 287 MAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTDKG 466
           MA++LGY G  Y G+Q NP   TI             I+Q + ++   + F R++RTDKG
Sbjct: 1   MALVLGYLGTGYQGIQYNPPAHTIDNELFKALVATNCISQSNSDDFSKSSFSRATRTDKG 60

Query: 467 VSAAEQVVSLKL-----PLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYSYT 631
           V A   +V+LK+     P +V   E+N+ LP+ I+++ V  V  +FN++     R Y Y 
Sbjct: 61  VHALTNLVALKMQRYEVPQQVKA-ELNEILPDDIRIWDVVPVKKKFNARVMAGTRHYRYV 119

Query: 632 LPTY 643
           +PT+
Sbjct: 120 IPTF 123


>UniRef50_Q00ST8 Cluster: TRNA pseudouridylate synthase; n=2;
           Ostreococcus|Rep: TRNA pseudouridylate synthase -
           Ostreococcus tauri
          Length = 450

 Score = 79.4 bits (187), Expect = 7e-14
 Identities = 42/107 (39%), Positives = 62/107 (57%), Gaps = 2/107 (1%)
 Frame = +2

Query: 275 KRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSR 454
           K++K A+   Y G  Y GMQRNPGV+TI             I+  +  +    Q+ R++R
Sbjct: 40  KKRKCALTFAYVGAGYAGMQRNPGVRTIEGELEGAIARAGGISDANAGDFAKVQWTRAAR 99

Query: 455 TDKGVSAAEQVVSLKLPLEVN--VEEINKRLPETIKVFAVKRVTNRF 589
           TDKGVSA  QV++LK+ +E +  +  IN+ LPE  +VF + RVT  +
Sbjct: 100 TDKGVSAVGQVIALKMVMEPDGMLARINEALPERFEVFGIDRVTGGY 146


>UniRef50_A2QZ58 Cluster: Putative frameshift; n=1; Aspergillus
           niger|Rep: Putative frameshift - Aspergillus niger
          Length = 567

 Score = 76.6 bits (180), Expect = 5e-13
 Identities = 43/125 (34%), Positives = 71/125 (56%), Gaps = 2/125 (1%)
 Frame = +2

Query: 266 ERIKRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQR 445
           +R  +KK+A+LLGYSG  Y GMQ +   +TI             I++ +  + + +   R
Sbjct: 114 QRRPKKKVAVLLGYSGTGYKGMQLSETEKTIEGELFAAFVAAGAISKANATDPKKSSLVR 173

Query: 446 SSRTDKGVSAAEQVVSLKLPLEVN--VEEINKRLPETIKVFAVKRVTNRFNSKSKCNARS 619
            +RTDKGV AA  +VSLKL +E +  +++IN++L   I+V+ +      F+S   C++R 
Sbjct: 174 CARTDKGVHAAGNIVSLKLIVEDDDIIQKINEKLSSQIRVWDILVTNKSFSSYQLCDSRI 233

Query: 620 YSYTL 634
           Y Y +
Sbjct: 234 YEYLI 238


>UniRef50_Q5K777 Cluster: Pseudouridylate synthase, putative; n=2;
           Filobasidiella neoformans|Rep: Pseudouridylate synthase,
           putative - Cryptococcus neoformans (Filobasidiella
           neoformans)
          Length = 560

 Score = 74.1 bits (174), Expect = 3e-12
 Identities = 46/153 (30%), Positives = 79/153 (51%), Gaps = 9/153 (5%)
 Frame = +2

Query: 212 RAHRDWETKPPGEIKKPYERIKRKKMAMLLGYSGVEYYGMQ-RNPGVQTIXXXXXXXXXX 388
           RA R WE   P E     +R+ +++ A+L+GY G  Y GMQ ++   +TI          
Sbjct: 103 RAQRAWE---PSEKTNGEKRLPKRRCAVLIGYCGTGYQGMQIQDHTDRTIEGEVFAALVK 159

Query: 389 XXYITQEDFENAQNAQFQRSSRTDKGVSAAEQVVSLKLPLEVNVEE--------INKRLP 544
              ++ ++  +A+     R++RTD GV AA  V+S+K+  E  + E        +N  LP
Sbjct: 160 AGAVSADNAIDARKVDIARAARTDAGVHAAGNVISIKMITEPPLPEGFKDVAEYVNTFLP 219

Query: 545 ETIKVFAVKRVTNRFNSKSKCNARSYSYTLPTY 643
           + I+++   R    FN+++  ++R Y Y LP+Y
Sbjct: 220 DQIRMWGWVRTVKSFNARTAADSRIYEYLLPSY 252


>UniRef50_A7NY39 Cluster: Chromosome chr6 scaffold_3, whole genome
           shotgun sequence; n=2; Vitis vinifera|Rep: Chromosome
           chr6 scaffold_3, whole genome shotgun sequence - Vitis
           vinifera (Grape)
          Length = 504

 Score = 72.9 bits (171), Expect = 6e-12
 Identities = 47/150 (31%), Positives = 74/150 (49%), Gaps = 14/150 (9%)
 Frame = +2

Query: 230 ETKPPGEIKKPYERIKRKKMAMLLGYSGVEYYG--MQRNPG-VQTIXXXXXXXXXXXXYI 400
           E+ P   ++K +E  ++KK+ M +GY G  Y G  MQR+   + TI             I
Sbjct: 47  ESNPDQSVQK-WESFRKKKVVMRVGYVGTNYRGLQMQRDESSLSTIEGELETAVFKAGGI 105

Query: 401 TQEDFENAQNAQFQRSSRTDKGVSAAEQVVSLKLPLEVNVEE-----------INKRLPE 547
              ++ N     + RSSRTDKGV +   ++SLK+ +  N  +           +N  LP 
Sbjct: 106 RDSNYGNLHKIGWDRSSRTDKGVHSLATMISLKMEIPANAWKEDPNGIALANYVNFHLPN 165

Query: 548 TIKVFAVKRVTNRFNSKSKCNARSYSYTLP 637
            IKVF++      F+++ +C+ R YSY LP
Sbjct: 166 NIKVFSILPSQRSFDARRECDLRRYSYLLP 195


>UniRef50_Q4D3D3 Cluster: Putative uncharacterized protein; n=3;
           Trypanosoma|Rep: Putative uncharacterized protein -
           Trypanosoma cruzi
          Length = 634

 Score = 72.1 bits (169), Expect = 1e-11
 Identities = 47/142 (33%), Positives = 73/142 (51%), Gaps = 17/142 (11%)
 Frame = +2

Query: 269 RIKRKKMAMLLGYSGVEYYGMQRN--PGVQTIXXXXXXXXXXXXYITQEDFENA---QNA 433
           ++ ++K+A++ GY G  Y G+Q N  PG  T+             I++E++E     Q  
Sbjct: 96  KLPKRKVAIIFGYVGERYCGLQWNHLPGYPTVEEELLRALHRTGMISKENYEQEKVQQKL 155

Query: 434 QFQRSSRTDKGVSAAEQVVSLKLPL--------EVNVEEINKRL----PETIKVFAVKRV 577
            ++R+SRTDKGV A   V+SL + L        E + +E  + L    P  I V+ +  V
Sbjct: 156 NWERASRTDKGVHALRNVISLNVMLPYAKGSTTEYDPQEARRILMTVLPHDIIVYEIVPV 215

Query: 578 TNRFNSKSKCNARSYSYTLPTY 643
           T  FN+   C AR+Y Y LPT+
Sbjct: 216 TRSFNAYMLCGARTYEYYLPTF 237


>UniRef50_O22928 Cluster: Putative tRNA pseudouridine synthase; n=1;
           Arabidopsis thaliana|Rep: Putative tRNA pseudouridine
           synthase - Arabidopsis thaliana (Mouse-ear cress)
          Length = 510

 Score = 71.7 bits (168), Expect = 1e-11
 Identities = 44/139 (31%), Positives = 70/139 (50%), Gaps = 14/139 (10%)
 Frame = +2

Query: 263 YERIKRKKMAMLLGYSGVEYYGMQ---RNPGVQTIXXXXXXXXXXXXYITQEDFENAQNA 433
           +E  ++KK+ + +GY G +Y G+Q    +P ++TI             I   ++ +    
Sbjct: 57  WESYRKKKVVIRIGYVGTDYRGLQIQRDDPSIKTIEGELEVAIYKAGGIRDSNYGDLHKI 116

Query: 434 QFQRSSRTDKGVSAAEQVVSLKLPLE-----------VNVEEINKRLPETIKVFAVKRVT 580
            + RSSRTDKGV +    +SLK+ +            V  + I+K LPE I+VF+V    
Sbjct: 117 GWARSSRTDKGVHSLATSISLKMEIPETAWKDDPQGTVLAKCISKHLPENIRVFSVLPSN 176

Query: 581 NRFNSKSKCNARSYSYTLP 637
            RF+ + +C  R YSY LP
Sbjct: 177 RRFDPRRECTLRKYSYLLP 195


>UniRef50_Q1XD12 Cluster: TRNA pseudouridine synthase; n=1;
           Pneumocystis carinii|Rep: TRNA pseudouridine synthase -
           Pneumocystis carinii
          Length = 227

 Score = 70.1 bits (164), Expect = 4e-11
 Identities = 34/84 (40%), Positives = 54/84 (64%), Gaps = 2/84 (2%)
 Frame = +2

Query: 398 ITQEDFENAQNAQFQRSSRTDKGVSAAEQVVSLKLPLEVN--VEEINKRLPETIKVFAVK 571
           I + + ++ + +   R++RTD+GV AA  V+SLKL +E    +E IN+ LPETI+V+ + 
Sbjct: 21  IAEMNADDPKKSSLNRAARTDRGVHAACNVLSLKLIIEQPNLLERINEALPETIRVWGIS 80

Query: 572 RVTNRFNSKSKCNARSYSYTLPTY 643
           R    FN ++ C AR Y Y +P+Y
Sbjct: 81  RTLKSFNPRTFCEARIYEYLVPSY 104


>UniRef50_O94295 Cluster: tRNA pseudouridine synthase 2; n=1;
           Schizosaccharomyces pombe|Rep: tRNA pseudouridine
           synthase 2 - Schizosaccharomyces pombe (Fission yeast)
          Length = 451

 Score = 70.1 bits (164), Expect = 4e-11
 Identities = 39/126 (30%), Positives = 70/126 (55%), Gaps = 6/126 (4%)
 Frame = +2

Query: 284 KMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTDK 463
           ++ +LLGYSG  Y+G+Q N  ++TI            Y+   + + A++    R++RTDK
Sbjct: 40  RIIILLGYSGYGYHGIQINNPLKTIEGDVVAVLKKLGYLKTNNID-AEHLCIARAARTDK 98

Query: 464 GVSAAEQVVSLKL----PLEVNV--EEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYS 625
           GV     ++SL L    PL++++   E+N+ L   I+V++V      FN +  C +R+Y 
Sbjct: 99  GVHTLRNLISLNLFVDKPLDISLLKTELNEALCSQIRVWSVFPAPKYFNPRISCESRTYE 158

Query: 626 YTLPTY 643
           Y +P++
Sbjct: 159 YLIPSF 164


>UniRef50_Q59S63 Cluster: tRNA pseudouridine synthase 1; n=2;
           Saccharomycetales|Rep: tRNA pseudouridine synthase 1 -
           Candida albicans (Yeast)
          Length = 450

 Score = 67.3 bits (157), Expect = 3e-10
 Identities = 31/71 (43%), Positives = 49/71 (69%), Gaps = 2/71 (2%)
 Frame = +2

Query: 437 FQRSSRTDKGVSAAEQVVSLKLPLEVN--VEEINKRLPETIKVFAVKRVTNRFNSKSKCN 610
           FQR++RTDKGV AA  V+SLK+ +E    + +IN  LP+ I+++ ++R T  F+ +  C+
Sbjct: 41  FQRAARTDKGVHAAGNVISLKMIIEDPEIINKINDLLPKQIRIWGIQRATKGFDCRKCCS 100

Query: 611 ARSYSYTLPTY 643
           +R Y Y LPT+
Sbjct: 101 SRIYEYLLPTF 111


>UniRef50_Q10LR0 Cluster: TRNA pseudouridine synthase family
           protein, expressed; n=7; Oryza sativa|Rep: TRNA
           pseudouridine synthase family protein, expressed - Oryza
           sativa subsp. japonica (Rice)
          Length = 516

 Score = 64.9 bits (151), Expect = 2e-09
 Identities = 40/139 (28%), Positives = 67/139 (48%), Gaps = 14/139 (10%)
 Frame = +2

Query: 263 YERIKRKKMAMLLGYSGVEYYGMQRNPGVQ---TIXXXXXXXXXXXXYITQEDFENAQNA 433
           +E  ++K++ + +GY G EY G+Q+   +    TI             I + ++   Q  
Sbjct: 66  WESARKKRVVLRVGYVGTEYRGLQKQRELSADSTIESVLETAIFKAGGILESNYGKLQKV 125

Query: 434 QFQRSSRTDKGVSAAEQVVSLKLPLEVNVEE-----------INKRLPETIKVFAVKRVT 580
            ++RSSRTDKGV +   ++SLK+ +     E           IN  LP+ ++VF+V    
Sbjct: 126 GWERSSRTDKGVHSLATMISLKMEIPDRAWENDPDGIALSNFINSNLPDNVRVFSVLPAQ 185

Query: 581 NRFNSKSKCNARSYSYTLP 637
             F+ + +C  R Y Y LP
Sbjct: 186 RSFDVRRECLYREYLYLLP 204


>UniRef50_A2XGH5 Cluster: Putative uncharacterized protein; n=1;
           Oryza sativa (indica cultivar-group)|Rep: Putative
           uncharacterized protein - Oryza sativa subsp. indica
           (Rice)
          Length = 264

 Score = 64.9 bits (151), Expect = 2e-09
 Identities = 40/139 (28%), Positives = 67/139 (48%), Gaps = 14/139 (10%)
 Frame = +2

Query: 263 YERIKRKKMAMLLGYSGVEYYGMQRNPGVQ---TIXXXXXXXXXXXXYITQEDFENAQNA 433
           +E  ++K++ + +GY G EY G+Q+   +    TI             I + ++   Q  
Sbjct: 66  WESARKKRVVLRVGYVGTEYRGLQKQRELSADSTIESVLETAIFKAGGILESNYGKLQKV 125

Query: 434 QFQRSSRTDKGVSAAEQVVSLKLPLEVNVEE-----------INKRLPETIKVFAVKRVT 580
            ++RSSRTDKGV +   ++SLK+ +     E           IN  LP+ ++VF+V    
Sbjct: 126 GWERSSRTDKGVHSLATMISLKMEIPDRAWENDPDGIALSNFINSNLPDNVRVFSVLPAQ 185

Query: 581 NRFNSKSKCNARSYSYTLP 637
             F+ + +C  R Y Y LP
Sbjct: 186 RSFDVRRECLYREYLYLLP 204


>UniRef50_Q8SS41 Cluster: Pseudouridylate synthase; n=1;
           Encephalitozoon cuniculi|Rep: Pseudouridylate synthase -
           Encephalitozoon cuniculi
          Length = 345

 Score = 64.9 bits (151), Expect = 2e-09
 Identities = 37/124 (29%), Positives = 66/124 (53%), Gaps = 4/124 (3%)
 Frame = +2

Query: 284 KMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTDK 463
           ++ +L+GY G  Y+G+Q N  + T+             I++ +  + +    + SSRTDK
Sbjct: 4   RVGLLVGYDGSRYHGLQFNKDLDTVEKKIVECLLRMDAISERNAGDPRKIHIKSSSRTDK 63

Query: 464 GVSAAEQVVSLKLPLEVNVEEIN--KRL--PETIKVFAVKRVTNRFNSKSKCNARSYSYT 631
           GV AA  +VS+K+ L V+ E ++  + L   E I ++ + R+T       +  +R+Y Y 
Sbjct: 64  GVHAALNLVSVKIELGVSPELVSGLRELLSKEGIHLYDIVRLTKSIVPSKQAISRTYEYI 123

Query: 632 LPTY 643
           +PTY
Sbjct: 124 VPTY 127


>UniRef50_O74451 Cluster: Pseudouridylate synthase; n=1;
           Schizosaccharomyces pombe|Rep: Pseudouridylate synthase
           - Schizosaccharomyces pombe (Fission yeast)
          Length = 413

 Score = 63.3 bits (147), Expect = 5e-09
 Identities = 39/125 (31%), Positives = 63/125 (50%), Gaps = 5/125 (4%)
 Frame = +2

Query: 278 RKKMAM-LLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSR 454
           RK+M   ++ Y G  + G+Q N  V+TI             + Q + ++ +  +   ++R
Sbjct: 35  RKRMVYCVVSYRGTGFAGLQYNANVKTIQDTLFQAFARVGAVVQVNADSPKKIRMCSAAR 94

Query: 455 TDKGVSAAEQVVSLKL----PLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSY 622
           TDKGV A   V+ LK+    PL   V  +N  LP  I+V+ + R  N F+  + C++R Y
Sbjct: 95  TDKGVHAIVNVLGLKVLDNQPLPHVVNLVNDILPPCIRVWKMARTFNSFSPHTVCDSRVY 154

Query: 623 SYTLP 637
            Y LP
Sbjct: 155 EYWLP 159


>UniRef50_A5ULI2 Cluster: Pseudouridylate synthase; n=1;
           Methanobrevibacter smithii ATCC 35061|Rep:
           Pseudouridylate synthase - Methanobrevibacter smithii
           (strain PS / ATCC 35061 / DSM 861)
          Length = 290

 Score = 63.3 bits (147), Expect = 5e-09
 Identities = 38/119 (31%), Positives = 60/119 (50%), Gaps = 1/119 (0%)
 Frame = +2

Query: 281 KKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTD 460
           K+ A+ +GY G  ++G QR P ++T+            YI     ++ + ++F+ + RTD
Sbjct: 2   KRTALKIGYIGTNFHGFQRQPDLRTVEEELIYHLRKLGYI-----DDLKKSRFRIAGRTD 56

Query: 461 KGVSAAEQVVSLKLPLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSK-CNARSYSYTL 634
            GV +   V+S +   EV V EIN  LP+ I++ A   V  RF  K +    R Y Y L
Sbjct: 57  AGVHSLGNVISFQSEKEVRVNEINNSLPDDIQILAKAPV--RFGFKPRYAEMRQYRYVL 113


>UniRef50_A4S8M4 Cluster: Predicted protein; n=2; Ostreococcus|Rep:
           Predicted protein - Ostreococcus lucimarinus CCE9901
          Length = 556

 Score = 60.9 bits (141), Expect = 3e-08
 Identities = 44/137 (32%), Positives = 64/137 (46%), Gaps = 16/137 (11%)
 Frame = +2

Query: 275 KRKKMAMLLGYSGVEYYGMQRN---PGVQTIXXXXXXXXXXXXYITQEDFENA--QNAQF 439
           K+K +A++L Y G  Y G   N   P   T+             I   ++ +   Q  ++
Sbjct: 87  KKKPVAIVLAYVGQGYKGNTHNAQAPRGTTVDDVVEDALFAWGGILMPNYRSRGLQRLKW 146

Query: 440 QRSSRTDKGVSAAEQVVSLKLPLEVNV-----------EEINKRLPETIKVFAVKRVTNR 586
            RSSRTDKGVS+   VVSL+  ++  V            EI K LPE ++ FAV      
Sbjct: 147 SRSSRTDKGVSSLCTVVSLRAEIDPEVWTKDVEARETAREITKHLPEDVECFAVYNTPKS 206

Query: 587 FNSKSKCNARSYSYTLP 637
           F ++ +C  R+Y Y LP
Sbjct: 207 FQARRECIMRTYEYLLP 223


>UniRef50_Q54TQ3 Cluster: Putative uncharacterized protein; n=1;
           Dictyostelium discoideum AX4|Rep: Putative
           uncharacterized protein - Dictyostelium discoideum AX4
          Length = 504

 Score = 59.7 bits (138), Expect = 6e-08
 Identities = 39/138 (28%), Positives = 69/138 (50%), Gaps = 14/138 (10%)
 Frame = +2

Query: 269 RIKRKKM--AMLLGYSGVEYYGMQRNPGVQ--TIXXXXXXXXXXXXYITQEDFENAQNAQ 436
           +I +KK+  AM+ GY G  YYG+     ++  +I            +I   +    +  +
Sbjct: 83  KINKKKLSVAMVFGYDGTGYYGLGYQVDIKYPSIENLIEKVLFRCGHILPSNVGELKRLK 142

Query: 437 FQRSSRTDKGVSAAEQVVSLKLPLEVN----------VEEINKRLPETIKVFAVKRVTNR 586
           +  SSRTDKGV +   V+S  L ++ N          ++ IN  LP +I++F+  +V+  
Sbjct: 143 WSHSSRTDKGVHSLATVISCFLVVDDNTFKNDINQTFIDTINNYLPSSIRLFSACKVSRS 202

Query: 587 FNSKSKCNARSYSYTLPT 640
           F ++ K   RSY+Y +P+
Sbjct: 203 FQARKKGIERSYNYMVPS 220


>UniRef50_A4RAI8 Cluster: Putative uncharacterized protein; n=1;
           Magnaporthe grisea|Rep: Putative uncharacterized protein
           - Magnaporthe grisea (Rice blast fungus) (Pyricularia
           grisea)
          Length = 720

 Score = 59.3 bits (137), Expect = 8e-08
 Identities = 32/88 (36%), Positives = 49/88 (55%)
 Frame = +2

Query: 266 ERIKRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQR 445
           ER  +KK+A+L+GY+G  Y GMQ N   +TI             I++ +  + +     R
Sbjct: 107 ERKPKKKVAVLIGYAGTGYKGMQINHFEKTIEGDLFRAFVDAGAISKANASDPKKVSLMR 166

Query: 446 SSRTDKGVSAAEQVVSLKLPLEVNVEEI 529
            +RTDKGV AA  V+SLKL + +  +E+
Sbjct: 167 CARTDKGVHAASNVISLKLIVPLEEKEL 194



 Score = 40.3 bits (90), Expect = 0.039
 Identities = 16/42 (38%), Positives = 25/42 (59%)
 Frame = +2

Query: 518 VEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYSYTLPTY 643
           V  IN  LP+ I+V+ + R  N F+    C++R Y Y +PT+
Sbjct: 291 VARINSHLPDQIRVWDILRTNNSFSCYQACDSRWYEYLMPTH 332


>UniRef50_A3F4X8 Cluster: TRNA pseudouridine synthase A; n=1; Taenia
           asiatica|Rep: TRNA pseudouridine synthase A - Taenia
           asiatica (Asian tapeworm)
          Length = 123

 Score = 57.6 bits (133), Expect = 2e-07
 Identities = 30/66 (45%), Positives = 39/66 (59%)
 Frame = +2

Query: 281 KKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTD 460
           +K A+L+ YSGV + GMQRN G +TI            YI +E  +N     FQR+S+TD
Sbjct: 57  RKCAILVVYSGVGFCGMQRNEGFRTIEGELMMALCNAGYILEEHMKNPSMICFQRASKTD 116

Query: 461 KGVSAA 478
           K VSAA
Sbjct: 117 KNVSAA 122


>UniRef50_A6RCJ6 Cluster: Putative uncharacterized protein; n=1;
           Ajellomyces capsulatus NAm1|Rep: Putative
           uncharacterized protein - Ajellomyces capsulatus NAm1
          Length = 634

 Score = 57.6 bits (133), Expect = 2e-07
 Identities = 37/99 (37%), Positives = 55/99 (55%), Gaps = 2/99 (2%)
 Frame = +2

Query: 266 ERIKRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQR 445
           +R  +KK+A++LGYSG  Y GMQ +   +TI             I++ +  + + +   R
Sbjct: 116 QRRPKKKVAVMLGYSGSGYKGMQLSETEKTIEGDLFTAFVAAGAISKANATDPKKSSLVR 175

Query: 446 SSRTDKGVSAAEQVVSLKLPLEVN--VEEINKRLPETIK 556
            +RTDKGV AA  VVSLKL +E    V++IN  L   I+
Sbjct: 176 CARTDKGVHAAGNVVSLKLIVEDPNVVQKINGHLSPQIR 214


>UniRef50_A2SU30 Cluster: Pseudouridylate synthase; n=1;
           Methanocorpusculum labreanum Z|Rep: Pseudouridylate
           synthase - Methanocorpusculum labreanum (strain ATCC
           43576 / DSM 4855 / Z)
          Length = 281

 Score = 57.6 bits (133), Expect = 2e-07
 Identities = 37/119 (31%), Positives = 52/119 (43%), Gaps = 1/119 (0%)
 Frame = +2

Query: 284 KMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTDK 463
           K+A L GY G  + G Q  P  +T+                  F +A+ A F+ + RTDK
Sbjct: 2   KLAFLAGYRGQNFAGSQYQPHKRTVEGEFVAGGIELGL-----FSDAKEAHFRTAGRTDK 56

Query: 464 GVSAAEQVVSLKLPL-EVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYSYTLP 637
           GVSA  Q+ S+     E+ +E +N  LP+ I       V   F  +     RSY Y  P
Sbjct: 57  GVSARRQLFSITTEKPELAIEALNFHLPDDIWCIGAAEVDEEFYPRYAARERSYRYYFP 115


>UniRef50_O26928 Cluster: tRNA pseudouridine synthase A; n=1;
           Methanothermobacter thermautotrophicus str. Delta H|Rep:
           tRNA pseudouridine synthase A - Methanobacterium
           thermoautotrophicum
          Length = 275

 Score = 57.6 bits (133), Expect = 2e-07
 Identities = 38/118 (32%), Positives = 55/118 (46%)
 Frame = +2

Query: 281 KKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTD 460
           +K+A+ + Y G  Y+G QR P V T+             I     E+ + A+FQ + RTD
Sbjct: 2   RKIALKVAYIGTNYHGFQRQPDVPTVEGKLLEALEGAGII-----EDPKRARFQIAGRTD 56

Query: 461 KGVSAAEQVVSLKLPLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYSYTL 634
           +GV A    VS     +++V +IN  LP  I+V A   V   F  +     R Y Y L
Sbjct: 57  RGVHALGNFVSFFTEEDIHVNQINDLLPRDIRVLAWASVMYPFKVRYPLE-RHYRYIL 113


>UniRef50_Q54LM5 Cluster: Putative uncharacterized protein; n=1;
           Dictyostelium discoideum AX4|Rep: Putative
           uncharacterized protein - Dictyostelium discoideum AX4
          Length = 615

 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 37/146 (25%), Positives = 67/146 (45%), Gaps = 16/146 (10%)
 Frame = +2

Query: 248 EIKKPYERIKRKKMAMLLGYSGVEYYGMQRNPGVQ--TIXXXXXXXXXXXXYITQEDFEN 421
           EI++  +   +K MA+   Y+G +YYG   +  ++   I            +I  E+  N
Sbjct: 137 EIEQNLKDKSKKPMALCFAYNGSKYYGSSYSFDIRFPAIENLIEKSLIRNGHIALENIGN 196

Query: 422 AQNAQFQRSSRTDKGVSAAEQVVSLKL--------------PLEVNVEEINKRLPETIKV 559
            +  +  RSSRTDKGV +   V+S  L              P +  ++ IN+ LP  I++
Sbjct: 197 LKRIKLSRSSRTDKGVHSVSTVISAFLLIDKETERLAQFGTPPQYFIDNINRYLPSDIRL 256

Query: 560 FAVKRVTNRFNSKSKCNARSYSYTLP 637
            +  + +  F ++    +R Y+Y +P
Sbjct: 257 ISATKPSRTFRARPASKSRVYNYLVP 282


>UniRef50_Q4Q9E9 Cluster: Pseudouridylate synthase-like protein;
           n=3; Leishmania|Rep: Pseudouridylate synthase-like
           protein - Leishmania major
          Length = 696

 Score = 54.8 bits (126), Expect = 2e-06
 Identities = 31/82 (37%), Positives = 46/82 (56%), Gaps = 9/82 (10%)
 Frame = +2

Query: 425 QNAQFQRSSRTDKGVSAAEQVVSLKLPLEVN---------VEEINKRLPETIKVFAVKRV 577
           ++  F RS RTD+GV A   +VSL +P EV           E++N++LP T++V  V ++
Sbjct: 78  EHHHFARSCRTDRGVHAIRNMVSLFVPKEVFEKMGQAEGICEKLNRQLPATVRVANVMQL 137

Query: 578 TNRFNSKSKCNARSYSYTLPTY 643
           +  F  +  CN R Y Y LP Y
Sbjct: 138 SGSFIPRHCCNRRVYRYMLPLY 159


>UniRef50_A2QE34 Cluster: Catalytic activity: tRNA uridine <=> tRNA
           pseudouridine; n=1; Aspergillus niger|Rep: Catalytic
           activity: tRNA uridine <=> tRNA pseudouridine -
           Aspergillus niger
          Length = 517

 Score = 54.0 bits (124), Expect = 3e-06
 Identities = 42/147 (28%), Positives = 66/147 (44%), Gaps = 9/147 (6%)
 Frame = +2

Query: 215 AHRDWETKPPGEIKKPYE----RIKRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXX 382
           A +  + KPP   K   E    R   + +A+   Y G  Y G++   G  T         
Sbjct: 81  AEKKKQVKPPKPPKPRREIDPSRYNTRFIALKFAYLGQRYNGLEHANGNATPLPTIEEEM 140

Query: 383 XXXXYITQED---FENAQNAQFQRSSRTDKGVSAAEQVVSLKLPLEV-NVEEINKRLPET 550
                 T+E    + N    ++ ++ RTD+GVSA  QV+ +++  E+  V  +NK LPE 
Sbjct: 141 YKALRKTRETKPYYINWDGCEYSKAGRTDRGVSAFGQVIGIRVRNELPYVSMLNKVLPED 200

Query: 551 IKVFA-VKRVTNRFNSKSKCNARSYSY 628
           I+V A   R    F+++  C  R Y Y
Sbjct: 201 IRVLAWCPRPPEGFDARFSCGERHYKY 227


>UniRef50_Q2NHB4 Cluster: Pseudouridylate synthase; n=1;
           Methanosphaera stadtmanae DSM 3091|Rep: Pseudouridylate
           synthase - Methanosphaera stadtmanae (strain DSM 3091)
          Length = 274

 Score = 54.0 bits (124), Expect = 3e-06
 Identities = 31/119 (26%), Positives = 56/119 (47%)
 Frame = +2

Query: 281 KKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTD 460
           +++A+ + Y G  ++G QR P  +T+             I     E+   A +  + RTD
Sbjct: 2   RRVALKIAYIGSNFHGYQRQPNYRTVEGELLRVFKETNII-----EDTWTAHYSVAGRTD 56

Query: 461 KGVSAAEQVVSLKLPLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYSYTLP 637
           KGV +   V+S     ++++ ++N  LP+ IK+    RV   F  +     R+Y+Y  P
Sbjct: 57  KGVHSTGNVISFITDEDIHINQLNGLLPDDIKIIGEARVPYGFKVRFPL-TRTYTYIQP 114


>UniRef50_A2DE30 Cluster: tRNA pseudouridine synthase family
           protein; n=1; Trichomonas vaginalis G3|Rep: tRNA
           pseudouridine synthase family protein - Trichomonas
           vaginalis G3
          Length = 345

 Score = 53.6 bits (123), Expect = 4e-06
 Identities = 34/124 (27%), Positives = 61/124 (49%), Gaps = 8/124 (6%)
 Frame = +2

Query: 293 MLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTDKGVS 472
           +L  Y G +Y+G+Q+N    T+            +++ +   N    ++  +SRTD GV 
Sbjct: 31  LLYRYIGTQYHGLQQNIDTHTVEKELFQALISAGFLSDQANCNLNRIKWSEASRTDAGVH 90

Query: 473 AAEQVVSLK------LPLEVNVEEINKRLPETIKVFAVKRVTNR--FNSKSKCNARSYSY 628
           A  QV+S K      + +    + INK+LP T  +  +  +T R  F ++    +R+Y++
Sbjct: 91  ACAQVLSFKASGLKGICIADIPDLINKQLPRTSDIEIITCITLRRQFYAQKFAESRNYNF 150

Query: 629 TLPT 640
            LPT
Sbjct: 151 LLPT 154


>UniRef50_Q22TA6 Cluster: Pseudouridylate synthase; n=1; Tetrahymena
           thermophila SB210|Rep: Pseudouridylate synthase -
           Tetrahymena thermophila SB210
          Length = 481

 Score = 53.2 bits (122), Expect = 5e-06
 Identities = 34/133 (25%), Positives = 56/133 (42%)
 Frame = +2

Query: 230 ETKPPGEIKKPYERIKRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQE 409
           E K   + +  +E  +++  A+ + Y G+ Y G+                      +   
Sbjct: 95  EQKQNNKKESLFEIYQQQHYALKMSYVGINYQGLAYQQETDNTVEEQLFKALEKTTL--- 151

Query: 410 DFENAQNAQFQRSSRTDKGVSAAEQVVSLKLPLEVNVEEINKRLPETIKVFAVKRVTNRF 589
             +N  N  F RS RTDKGVSA  QV+ + L   + + E N    + I++    +V   F
Sbjct: 152 -IKNRDNCNFTRSGRTDKGVSALGQVIGITLRTSIKIGE-NIDEIDDIRILGCSKVDPAF 209

Query: 590 NSKSKCNARSYSY 628
           N++  C  R Y Y
Sbjct: 210 NARFDCQKRIYKY 222


>UniRef50_A7ASP1 Cluster: tRNA pseudouridine synthase, putative;
           n=1; Babesia bovis|Rep: tRNA pseudouridine synthase,
           putative - Babesia bovis
          Length = 414

 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 38/133 (28%), Positives = 56/133 (42%), Gaps = 18/133 (13%)
 Frame = +2

Query: 293 MLLGYSGVEYYGMQ-----RNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRT 457
           ++L Y G  Y+G Q      + G+ T+             I      N    Q  ++SRT
Sbjct: 31  IVLSYIGTNYHGFQIQRDAGDDGIDTVEARVINALVTTDAIHGSHKNNLGKLQLSKASRT 90

Query: 458 DKGVSAAEQVVSLKLPL-------------EVNVEEINKRLPETIKVFAVKRVTNRFNSK 598
           DKGV AA   +  +  L             +  V  +N  LP+ I+ F V RVT  F ++
Sbjct: 91  DKGVHAACTYIGGRFELSHLSAGEPGISKEQCLVSRLNTVLPDDIRCFQVLRVTRGFCAR 150

Query: 599 SKCNARSYSYTLP 637
           S C+ R Y Y +P
Sbjct: 151 SMCSKRMYEYVIP 163


>UniRef50_Q18DQ1 Cluster: Pseudouridylate synthase; n=1;
           Haloquadratum walsbyi DSM 16790|Rep: Pseudouridylate
           synthase - Haloquadratum walsbyi (strain DSM 16790)
          Length = 276

 Score = 51.2 bits (117), Expect = 2e-05
 Identities = 30/115 (26%), Positives = 51/115 (44%)
 Frame = +2

Query: 290 AMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTDKGV 469
           A  L Y G  + G QR P V T+               ++   +++ + +  + RTD GV
Sbjct: 7   AFRLAYDGRPFSGFQRQPSVPTVEDALFDALDSLDVFNRDT--DSKPSGYAAAGRTDAGV 64

Query: 470 SAAEQVVSLKLPLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYSYTL 634
           SA  Q V  + P       +N  LP +++ +A   V + F++      R+Y+Y L
Sbjct: 65  SALRQTVGFECPSWCTPRALNSELPTSVRAWASADVQSGFHATHDALQRTYTYYL 119


>UniRef50_A7D6F0 Cluster: tRNA pseudouridine synthase; n=1;
           Halorubrum lacusprofundi ATCC 49239|Rep: tRNA
           pseudouridine synthase - Halorubrum lacusprofundi ATCC
           49239
          Length = 293

 Score = 50.8 bits (116), Expect = 3e-05
 Identities = 33/116 (28%), Positives = 50/116 (43%), Gaps = 1/116 (0%)
 Frame = +2

Query: 290 AMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFE-NAQNAQFQRSSRTDKG 466
           A  + Y G EY G QR P   T+             + + D   +A    +  + RTD G
Sbjct: 10  AFRVAYDGREYAGFQRQPHATTVEGTLLRALAKHGILDRGDGPTHATPPGYAAAGRTDAG 69

Query: 467 VSAAEQVVSLKLPLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYSYTL 634
           VSA  Q V+ + P  +     N  LP +++V+A   V   F++      R+Y Y L
Sbjct: 70  VSAVAQTVAFEAPDWLTPRAFNGHLPGSVRVWAAADVPAGFHATHDAVRRTYRYHL 125


>UniRef50_Q8U2C1 Cluster: tRNA pseudouridine synthase A; n=4;
           Thermococcaceae|Rep: tRNA pseudouridine synthase A -
           Pyrococcus furiosus
          Length = 266

 Score = 50.8 bits (116), Expect = 3e-05
 Identities = 34/121 (28%), Positives = 60/121 (49%), Gaps = 2/121 (1%)
 Frame = +2

Query: 284 KMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTDK 463
           ++A+ + Y G +++G QR P V+TI                 +FEN     F+ +SRTD+
Sbjct: 2   RVALKIAYDGTKFHGFQRQPNVRTIEGEILRALKDAGI----EFEN-----FKSASRTDR 52

Query: 464 GVSAAEQVVSLKLPLE--VNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYSYTLP 637
           GVSA   V++L    +   N   +N R+ + + ++ +  V   F+ +   N + Y Y LP
Sbjct: 53  GVSARGNVIALSTEDDRIKNPMVLNSRMSD-VWIWGIAEVPEDFHPRFWANTKVYRYYLP 111

Query: 638 T 640
           +
Sbjct: 112 S 112


>UniRef50_A0DFY8 Cluster: Pseudouridylate synthase; n=1; Paramecium
           tetraurelia|Rep: Pseudouridylate synthase - Paramecium
           tetraurelia
          Length = 414

 Score = 50.4 bits (115), Expect = 4e-05
 Identities = 36/124 (29%), Positives = 59/124 (47%), Gaps = 6/124 (4%)
 Frame = +2

Query: 275 KRKKMAMLLGYSGVEYYGMQRNPGVQ-TIXXXXXXXXXXXXYITQEDFENAQNAQFQRSS 451
           K  ++A  L Y G+ Y+G+++    Q TI             I     +N  +  + R+ 
Sbjct: 47  KFTRVAFKLAYVGINYHGLEQQINQQNTIENHLFKALQRVRMI-----DNRDDCNYTRAG 101

Query: 452 RTDKGVSAAEQVVSLKLPL-----EVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNAR 616
           RTDKGVSA   VV+L +       ++  + +N+ LPE I++     V  +FN++  C  R
Sbjct: 102 RTDKGVSAIGNVVALNVRKIGKSDKLYAQILNRVLPEDIQILDECIVDEKFNARYDCIKR 161

Query: 617 SYSY 628
            Y Y
Sbjct: 162 VYKY 165


>UniRef50_Q8R601 Cluster: tRNA pseudouridine synthase A; n=3;
           Fusobacterium nucleatum|Rep: tRNA pseudouridine synthase
           A - Fusobacterium nucleatum subsp. nucleatum
          Length = 247

 Score = 50.4 bits (115), Expect = 4e-05
 Identities = 36/125 (28%), Positives = 56/125 (44%), Gaps = 4/125 (3%)
 Frame = +2

Query: 272 IKRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSS 451
           ++RK + +   Y G  YYG QR P   T+             +T+E+  N  +A      
Sbjct: 3   MRRKNIKIEFRYDGSSYYGFQRQPNKITVQGEIEKVLRI---VTKEEI-NLISA-----G 53

Query: 452 RTDKGVSAAEQV----VSLKLPLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARS 619
           RTD+GV A  QV     S  +P+E     + + LP  I + +V+ V   FN++     R 
Sbjct: 54  RTDRGVHANHQVSNFYTSSNIPIEKYKYLLTRALPNDIDILSVEEVDENFNARHNAKMRE 113

Query: 620 YSYTL 634
           Y Y +
Sbjct: 114 YIYII 118


>UniRef50_UPI00015BE519 Cluster: UPI00015BE519 related cluster; n=1;
           unknown|Rep: UPI00015BE519 UniRef100 entry - unknown
          Length = 247

 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 35/122 (28%), Positives = 54/122 (44%), Gaps = 4/122 (3%)
 Frame = +2

Query: 281 KKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTD 460
           K     + + G  Y G Q  P V TI            YI  +     Q  +    SRTD
Sbjct: 2   KNYKFTISFVGTNYSGWQYQPNVPTIQNEVEEKLY---YIVNKKKPIKQKIRAIGCSRTD 58

Query: 461 KGVSAAEQVVSLKLPLEVNV----EEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYSY 628
           KGV A E V ++K+  + ++    + +N  LP+ IK+  ++ V   FNS+     ++Y Y
Sbjct: 59  KGVHAIEFVFNVKMEFDKDLNFLRKALNSALPKDIKIHNIEEVPLEFNSRFDALKKTYIY 118

Query: 629 TL 634
            L
Sbjct: 119 KL 120


>UniRef50_UPI0000DB7775 Cluster: PREDICTED: similar to CG3045-PA;
           n=2; Endopterygota|Rep: PREDICTED: similar to CG3045-PA
           - Apis mellifera
          Length = 406

 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 46/164 (28%), Positives = 72/164 (43%), Gaps = 15/164 (9%)
 Frame = +2

Query: 191 LTRYNKRRAHRDWETKPPGEIKKPYERIKRKKMAMLLG--YSGVEYYGMQRNPGVQTIXX 364
           L + NK+  ++D   K     +KP++  K  K  +LL   Y G +Y G      VQ    
Sbjct: 33  LEKENKQLKNKDIIRKS----QKPFDFSKCNKRHILLKFYYLGWDYNGFV----VQESID 84

Query: 365 XXXXXXXXXXYITQEDFENAQNAQFQRSSRTDKGVSAAEQVVSLKLPLEVNVEE------ 526
                      I     E+ + + + R  RTDKGVS+  QV+SL +  ++N E+      
Sbjct: 85  NTIEEHLFEALIKSCCIESRETSNYHRCGRTDKGVSSFSQVISLDIRSKLNPEDQYKLED 144

Query: 527 -------INKRLPETIKVFAVKRVTNRFNSKSKCNARSYSYTLP 637
                  +N+ LP  I+  A   V N F+++  C  R+Y Y  P
Sbjct: 145 ELPYCKILNRLLPSNIRCIAWCPVPNDFSARFNCKFRTYKYFFP 188


>UniRef50_A5PKS2 Cluster: LOC100101318 protein; n=4; Xenopus|Rep:
           LOC100101318 protein - Xenopus laevis (African clawed
           frog)
          Length = 507

 Score = 50.0 bits (114), Expect = 5e-05
 Identities = 28/81 (34%), Positives = 42/81 (51%), Gaps = 7/81 (8%)
 Frame = +2

Query: 416 ENAQNAQFQRSSRTDKGVSAAEQVVSLKLPLEVN-------VEEINKRLPETIKVFAVKR 574
           E+ Q + + R  RTD+GVSA  QV+SL L            V  +N+ LP  I+V +   
Sbjct: 100 ESRQTSNYHRCGRTDRGVSALAQVISLDLRCSAEGKPEIRYVHILNRVLPPDIRVLSWAP 159

Query: 575 VTNRFNSKSKCNARSYSYTLP 637
           V   F+++  C +R+Y Y  P
Sbjct: 160 VPPSFSARFSCGSRTYRYLFP 180


>UniRef50_Q5UXW0 Cluster: tRNA pseudouridine synthase A; n=3;
           Halobacteriaceae|Rep: tRNA pseudouridine synthase A -
           Haloarcula marismortui (Halobacterium marismortui)
          Length = 275

 Score = 49.6 bits (113), Expect = 6e-05
 Identities = 33/115 (28%), Positives = 50/115 (43%)
 Frame = +2

Query: 290 AMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTDKGV 469
           A  + Y G  Y+G QR P V T+                E  E   + ++  + RTD GV
Sbjct: 3   AYRVAYDGQPYHGFQRQPDVDTVEGRLRSALVRLGVC--ERGEGLPD-RYAAAGRTDAGV 59

Query: 470 SAAEQVVSLKLPLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYSYTL 634
           SA  Q V+   P  ++    N  LP  ++V+A   V   F++      R+Y+Y L
Sbjct: 60  SARTQTVAFDAPAWLSPAAFNGELPNDVRVWASADVPEDFHATHDAAERTYTYYL 114


>UniRef50_Q5NG36 Cluster: tRNA pseudouridine synthase A; n=11;
           Francisella tularensis|Rep: tRNA pseudouridine synthase
           A - Francisella tularensis subsp. tularensis
          Length = 258

 Score = 49.6 bits (113), Expect = 6e-05
 Identities = 27/74 (36%), Positives = 40/74 (54%), Gaps = 4/74 (5%)
 Frame = +2

Query: 425 QNAQFQRSSRTDKGVSAAEQVVSL----KLPLEVNVEEINKRLPETIKVFAVKRVTNRFN 592
           QN +   + RTD GV A  Q+V+       PL      +N  LP+ IK+ AV++V N FN
Sbjct: 41  QNIEVTCAGRTDTGVHATSQIVNFYSNADRPLSAWQRGVNALLPQDIKILAVQQVDNNFN 100

Query: 593 SKSKCNARSYSYTL 634
           S+     R+Y+Y +
Sbjct: 101 SRFTAINRTYNYII 114


>UniRef50_Q4Q3H7 Cluster: Putative uncharacterized protein; n=3;
           Leishmania|Rep: Putative uncharacterized protein -
           Leishmania major
          Length = 701

 Score = 49.2 bits (112), Expect = 8e-05
 Identities = 33/98 (33%), Positives = 51/98 (52%), Gaps = 6/98 (6%)
 Frame = +2

Query: 266 ERIKRK-KMAMLLGYSGVEYYGMQRN--PGVQTIXXXXXXXXXXXXYITQEDFENAQNAQ 436
           +R++RK K+ ++ GY G  Y G+Q N  P   T+             I++ +F N +  Q
Sbjct: 50  KRVRRKQKVGIIFGYVGECYCGLQWNHLPEYPTVEEALMKALFETDMISEVNFSNVKVQQ 109

Query: 437 ---FQRSSRTDKGVSAAEQVVSLKLPLEVNVEEINKRL 541
              F+R+SRTDKGV A   VVS+ + L  +     KR+
Sbjct: 110 LLNFERASRTDKGVHALRNVVSVAVMLPYDPSYTKKRV 147



 Score = 41.5 bits (93), Expect = 0.017
 Identities = 18/39 (46%), Positives = 23/39 (58%)
 Frame = +2

Query: 527 INKRLPETIKVFAVKRVTNRFNSKSKCNARSYSYTLPTY 643
           +N+ LP  I V+AV  VT  FN+   C  R Y Y LPT+
Sbjct: 190 LNEALPRDIHVYAVVPVTRSFNAYLNCGGRRYEYYLPTF 228


>UniRef50_A2E6F9 Cluster: tRNA pseudouridine synthase family
           protein; n=1; Trichomonas vaginalis G3|Rep: tRNA
           pseudouridine synthase family protein - Trichomonas
           vaginalis G3
          Length = 346

 Score = 48.4 bits (110), Expect = 1e-04
 Identities = 35/121 (28%), Positives = 53/121 (43%), Gaps = 8/121 (6%)
 Frame = +2

Query: 305 YSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTDKGVSAAEQ 484
           Y G  Y+G+Q N  V+TI             + +  ++      +  +SRTD GV A  Q
Sbjct: 39  YIGTGYHGLQYNEKVRTIDSDLFEGLEKSGILPEGSYKRRGKIAWNEASRTDAGVHACGQ 98

Query: 485 VVSLK----LPLEVNV--EEINKRLPE--TIKVFAVKRVTNRFNSKSKCNARSYSYTLPT 640
           ++  K      +E +   E INK LP   TIK+ +     + F  K     R Y+Y LP 
Sbjct: 99  LICFKSYEICDMECSQIPELINKNLPSDSTIKIMSCLCTNSPFPVKDFATHRKYNYLLPL 158

Query: 641 Y 643
           +
Sbjct: 159 H 159


>UniRef50_A0DJ25 Cluster: Pseudouridylate synthase; n=1; Paramecium
           tetraurelia|Rep: Pseudouridylate synthase - Paramecium
           tetraurelia
          Length = 297

 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 31/103 (30%), Positives = 52/103 (50%), Gaps = 21/103 (20%)
 Frame = +2

Query: 398 ITQEDFENAQNAQFQRSSRTDKGVSAAEQVVSLKLPLEVN-------------------- 517
           +++ + ++ +     R +RTD+GV A   VVSLKL ++                      
Sbjct: 26  VSELNADSIKKIGVSRGARTDRGVHALCNVVSLKLQIDQKYCSSMTNNKLVDKWNIDWDL 85

Query: 518 -VEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYSYTLPTY 643
            ++E+N +LP  IKV A+K VT  FN K + + R Y+Y  P++
Sbjct: 86  LIQELNSQLPSDIKVNAIKHVTQSFNVKHQADQRMYNYISPSF 128


>UniRef50_Q8TU65 Cluster: tRNA pseudouridine synthase A; n=5;
           Archaea|Rep: tRNA pseudouridine synthase A -
           Methanosarcina acetivorans
          Length = 269

 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 34/119 (28%), Positives = 54/119 (45%), Gaps = 2/119 (1%)
 Frame = +2

Query: 284 KMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTDK 463
           ++A+ L Y G E++G Q  P V+T+             I     E+ ++A +  + RTD 
Sbjct: 2   RVALKLAYIGTEFHGSQIQPNVETVEKELFKALRNLSII-----ESPKSADYTCAGRTDA 56

Query: 464 GVSAAEQVVSL--KLPLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYSYTL 634
           GV A  QVV+   + P       IN  LP  I  +A   V   F+++    +R Y Y +
Sbjct: 57  GVHALGQVVAFDTEKPNLAIPRVINSELPPAIWAWAHAEVPYYFDARRSAVSRHYHYVM 115


>UniRef50_A0E7K0 Cluster: Pseudouridylate synthase; n=1; Paramecium
           tetraurelia|Rep: Pseudouridylate synthase - Paramecium
           tetraurelia
          Length = 351

 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 39/150 (26%), Positives = 64/150 (42%), Gaps = 30/150 (20%)
 Frame = +2

Query: 278 RKKMAMLLGYSGVEYYGMQRNPGV--QTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSS 451
           ++K+ +  GY+G  Y+G+Q   GV  +T+             I +++  +   + + R +
Sbjct: 7   KQKVLLTFGYNGANYHGLQIQKGVEFETVESKLFQALKDSNLIMEQNANDLSKSGWSRGA 66

Query: 452 RTDKGVSAAEQVVSLKL---------PLEVNVEE-------------------INKRLPE 547
           RTDKGV A    +++KL          ++ N EE                   IN  LP 
Sbjct: 67  RTDKGVHALCNSIAVKLCINKEFFKDEIQQNEEEIVSKLRDKQKVDYSKVLNVINSNLPN 126

Query: 548 TIKVFAVKRVTNRFNSKSKCNARSYSYTLP 637
            IKV ++K VT  F+ +     R Y Y  P
Sbjct: 127 DIKVHSIKLVTQGFDVRKNARYRFYEYIAP 156


>UniRef50_Q8XLQ0 Cluster: tRNA pseudouridine synthase A 1; n=4;
           Clostridium|Rep: tRNA pseudouridine synthase A 1 -
           Clostridium perfringens
          Length = 248

 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 33/123 (26%), Positives = 56/123 (45%), Gaps = 5/123 (4%)
 Frame = +2

Query: 281 KKMAMLLGYSGVEYYGMQR-NPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRT 457
           + + + L Y G +Y G Q+ N     +             +T E+       Q     RT
Sbjct: 2   RNIKITLDYDGSKYKGWQKQNQKGSNVSTVQDKLEKVLTKMTSEEI------QLIGCGRT 55

Query: 458 DKGVSAAEQVVSLK----LPLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYS 625
           D GV A   V + K    + LE  +E IN+ LPE I+V  ++  + RF+++    +++Y 
Sbjct: 56  DSGVHAKNYVANFKTNSLMTLEQIIEYINEYLPEDIRVTEIREASERFHARFNVKSKTYE 115

Query: 626 YTL 634
           YT+
Sbjct: 116 YTI 118


>UniRef50_A2FDS7 Cluster: tRNA pseudouridine synthase family
           protein; n=1; Trichomonas vaginalis G3|Rep: tRNA
           pseudouridine synthase family protein - Trichomonas
           vaginalis G3
          Length = 365

 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 37/125 (29%), Positives = 61/125 (48%), Gaps = 8/125 (6%)
 Frame = +2

Query: 287 MAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTDKG 466
           +A+  GY G  Y+G   +   +T+             I+    + A   ++  SSRTD G
Sbjct: 40  IALCYGYLGTNYHGSSLHDQDKTVTLELQEALVNLGVISPNRTKGA--LKWSESSRTDTG 97

Query: 467 VSAAEQVVSLKL--PLEVNVEE----INKRLPET--IKVFAVKRVTNRFNSKSKCNARSY 622
           V AA+QV + +L  P  V V++    I K+L +   I+V+A  +    FN++   ++R Y
Sbjct: 98  VHAAKQVATFRLVLPEGVKVKDLPRLIQKQLSKNSPIRVWAAVKPGIIFNAQQSASSRRY 157

Query: 623 SYTLP 637
            Y LP
Sbjct: 158 HYLLP 162


>UniRef50_Q64EQ0 Cluster: Pseudouridylate synthase; n=1; uncultured
           archaeon GZfos10C7|Rep: Pseudouridylate synthase -
           uncultured archaeon GZfos10C7
          Length = 284

 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 37/127 (29%), Positives = 59/127 (46%), Gaps = 4/127 (3%)
 Frame = +2

Query: 266 ERIKRKKMAMLLGYSGVEYYGMQRNP--GVQTIXXXXXXXXXXXXYITQEDFENAQNAQF 439
           E  +++++A+ +GY G  Y+G Q  P   + TI             I     E+ + A +
Sbjct: 3   EERQKERIALKIGYIGTNYHGFQIQPRSALPTIEGELFKALKKQGII-----EDRKTANY 57

Query: 440 QRSSRTDKGVSAAEQVVSLKLPLE-VNVEEINKRLPE-TIKVFAVKRVTNRFNSKSKCNA 613
             + RTD GV A  QVVS     +      IN  LP+ +I V A+ +  + FN++    +
Sbjct: 58  SAAGRTDTGVHALAQVVSFVTSNQNTTPRMINSVLPDGSIWVSAIAKPYSGFNARRDAIS 117

Query: 614 RSYSYTL 634
           R Y Y L
Sbjct: 118 REYRYYL 124


>UniRef50_P70830 Cluster: tRNA pseudouridine synthase A; n=3;
           Borrelia burgdorferi group|Rep: tRNA pseudouridine
           synthase A - Borrelia burgdorferi (Lyme disease
           spirochete)
          Length = 246

 Score = 47.2 bits (107), Expect = 3e-04
 Identities = 30/123 (24%), Positives = 52/123 (42%), Gaps = 5/123 (4%)
 Frame = +2

Query: 281 KKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTD 460
           KK+   + Y G  Y+G Q  P   T+                    N +  +   S RTD
Sbjct: 2   KKILAEIAYDGSIYHGFQIQPTKPTVQGEIEKALMKI---------NKKKVKIHSSGRTD 52

Query: 461 KGVSAAEQVVSLKLPLEVNVEEINKR-----LPETIKVFAVKRVTNRFNSKSKCNARSYS 625
           KGV A +Q+++  + + + +  + K      L  +IK+  ++ V N F+ +     R YS
Sbjct: 53  KGVHAKKQIITFDIKINIQLNNLKKALNAILLKNSIKILKLRYVKNSFHPRFSAQKRKYS 112

Query: 626 YTL 634
           Y +
Sbjct: 113 YCI 115


>UniRef50_Q9UTB3 Cluster: Pseudouridylate synthase; n=1;
           Schizosaccharomyces pombe|Rep: Pseudouridylate synthase
           - Schizosaccharomyces pombe (Fission yeast)
          Length = 450

 Score = 46.4 bits (105), Expect = 6e-04
 Identities = 43/170 (25%), Positives = 72/170 (42%), Gaps = 9/170 (5%)
 Frame = +2

Query: 146 KDEENKSIDIVPNKLLTRYNKRRAHRDWETKPPGEIKKPYERIKRKKMAMLLGYSGVEYY 325
           K++ +   +I P  L      + A +D  + P  +  +P++  K   +A    Y G  Y 
Sbjct: 47  KNKLDNGNEIEPQHLSQELVLQHALQDASSLPKLKPVRPFQLEKTVFVAFKFAYCGWNYN 106

Query: 326 GM--QRNPG-VQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTDKGVSAAEQVVSL 496
           G+  Q  P  + T+             IT     +  +  F R  RTDKGVSA  QV+SL
Sbjct: 107 GLAYQLEPTPLPTVEGKVFEALLRAHLIT-----DPSSCSFSRCGRTDKGVSAMGQVISL 161

Query: 497 KL------PLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYSY 628
            +      P+ +  + +N+ LP  I++         F+++  C  R Y Y
Sbjct: 162 NVRHSERRPI-IYCDVLNRLLPADIRITGYAFPPEGFDARFSCKQRHYKY 210


>UniRef50_Q4UIU5 Cluster: Pseudouridylate synthase; n=2;
           Theileria|Rep: Pseudouridylate synthase - Theileria
           annulata
          Length = 478

 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 22/72 (30%), Positives = 38/72 (52%)
 Frame = +2

Query: 428 NAQFQRSSRTDKGVSAAEQVVSLKLPLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKC 607
           +++   SS+ D   +   Q        E  V+ +N  LPE I+ F ++RVT  F+++S C
Sbjct: 168 HSEINNSSKPDTSDNVELQSDGKLSKEEKFVQRLNAALPEDIRCFKIQRVTKGFDARSLC 227

Query: 608 NARSYSYTLPTY 643
           + R Y Y +P +
Sbjct: 228 SKRKYEYIIPEW 239


>UniRef50_Q6F1W2 Cluster: tRNA pseudouridine synthase A; n=3;
           Mollicutes|Rep: tRNA pseudouridine synthase A -
           Mesoplasma florum (Acholeplasma florum)
          Length = 251

 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 39/123 (31%), Positives = 59/123 (47%), Gaps = 6/123 (4%)
 Frame = +2

Query: 284 KMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQR--SSRT 457
           K  + L Y G +++G    P   TI             + +      +NA F+   +S+T
Sbjct: 3   KFLITLEYDGSDFHGWIEQPKTSTIQGE----------LNKAINRVTKNAVFKTIGASKT 52

Query: 458 DKGVSAAEQVVSLKL----PLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYS 625
           D GV A +Q V L L     L++  + INK LPETIKV +++ V   FN +     + YS
Sbjct: 53  DTGVHAIDQKVLLDLGFNPKLDLFKKAINKALPETIKVRSIEEVKQDFNIRDVL-YKEYS 111

Query: 626 YTL 634
           YT+
Sbjct: 112 YTI 114


>UniRef50_Q8KDR7 Cluster: tRNA pseudouridine synthase A; n=9;
           Chlorobiaceae|Rep: tRNA pseudouridine synthase A -
           Chlorobium tepidum
          Length = 247

 Score = 46.0 bits (104), Expect = 8e-04
 Identities = 34/123 (27%), Positives = 51/123 (41%), Gaps = 4/123 (3%)
 Frame = +2

Query: 278 RKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRT 457
           ++ + M + Y G  Y G QR PG   +             I QE            + RT
Sbjct: 5   KRTIKMQIEYDGTGYSGWQRQPG--DVVTVQGEIERVLERIMQEP------VSIDGAGRT 56

Query: 458 DKGVSAAEQVVSLK----LPLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYS 625
           D GV A  QV S      +PL   +   N  LP TI++ A+++    F+++    +R Y 
Sbjct: 57  DSGVHARRQVASFATCSPMPLGRLIYSANSLLPSTIRINAMRQAPESFHARFSATSREYR 116

Query: 626 YTL 634
           Y L
Sbjct: 117 YFL 119


>UniRef50_Q1FEL6 Cluster: Pseudouridylate synthase; n=1; Clostridium
           phytofermentans ISDg|Rep: Pseudouridylate synthase -
           Clostridium phytofermentans ISDg
          Length = 264

 Score = 45.2 bits (102), Expect = 0.001
 Identities = 34/131 (25%), Positives = 60/131 (45%), Gaps = 4/131 (3%)
 Frame = +2

Query: 260 PYERIKRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQF 439
           P E  +++ + +++ Y G  Y G QR P  +              ++++   E  +    
Sbjct: 2   PGEMDRKRNIKLIISYDGTNYSGWQRIP--KAANGDHSIQGLLEEFLSKVLLEPIK---L 56

Query: 440 QRSSRTDKGVSAAEQVVSL--KLPLEVNV--EEINKRLPETIKVFAVKRVTNRFNSKSKC 607
             S RTD GV A  QV +   +  L+VN+  +++N+ LPE IK+     V   F+S+   
Sbjct: 57  IGSGRTDTGVHALGQVANFYSRSNLDVNIIRQKMNQVLPEDIKILQANEVDLNFHSRFDA 116

Query: 608 NARSYSYTLPT 640
             + Y Y + T
Sbjct: 117 VEKIYQYIIDT 127


>UniRef50_A7HCM5 Cluster: tRNA-pseudouridine synthase I; n=2;
           Anaeromyxobacter|Rep: tRNA-pseudouridine synthase I -
           Anaeromyxobacter sp. Fw109-5
          Length = 265

 Score = 45.2 bits (102), Expect = 0.001
 Identities = 34/123 (27%), Positives = 53/123 (43%), Gaps = 4/123 (3%)
 Frame = +2

Query: 272 IKRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSS 451
           ++R+  A+ + Y G  + G QR PG+ T+                        A    ++
Sbjct: 1   MERRFYALRVAYEGGRFRGFQRQPGLPTVQDALEGALLAAGV----------RATLAVAA 50

Query: 452 RTDKGVSAAEQVVSLKLPLEVNVEEI----NKRLPETIKVFAVKRVTNRFNSKSKCNARS 619
           RTD GV A +QVVS      ++   +    N  LPE + V  V RV   F++++   AR 
Sbjct: 51  RTDAGVHALDQVVSFSARAALDPAALRGALNAALPEGVAVLEVLRVAPSFHARNTARARR 110

Query: 620 YSY 628
           Y Y
Sbjct: 111 YVY 113


>UniRef50_A0LIV1 Cluster: Pseudouridylate synthase; n=1;
           Syntrophobacter fumaroxidans MPOB|Rep: Pseudouridylate
           synthase - Syntrophobacter fumaroxidans (strain DSM
           10017 / MPOB)
          Length = 261

 Score = 45.2 bits (102), Expect = 0.001
 Identities = 35/126 (27%), Positives = 53/126 (42%), Gaps = 4/126 (3%)
 Frame = +2

Query: 263 YERIKRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQ 442
           Y+  +RK   ++L Y G  Y+G QR  GV TI              ++ +         +
Sbjct: 4   YDLPERKNFKLILEYDGSHYHGWQRQLGVLTIQEVLE---------SRLEVMLQSPVGVR 54

Query: 443 RSSRTDKGVSAAEQVVSLKLPLEVNVEE----INKRLPETIKVFAVKRVTNRFNSKSKCN 610
            S RTD GV A  QVV+  +   +  EE    IN  LP  I V   +     F+++    
Sbjct: 55  ASGRTDAGVHACGQVVNFHVHTRLRPEEILRGINSLLPPDIVVLHAEVAAESFHARFSAT 114

Query: 611 ARSYSY 628
            ++Y Y
Sbjct: 115 GKTYEY 120


>UniRef50_Q250I7 Cluster: Pseudouridylate synthase; n=2;
           Desulfitobacterium hafniense|Rep: Pseudouridylate
           synthase - Desulfitobacterium hafniense (strain Y51)
          Length = 271

 Score = 44.4 bits (100), Expect = 0.002
 Identities = 29/126 (23%), Positives = 52/126 (41%), Gaps = 4/126 (3%)
 Frame = +2

Query: 278 RKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRT 457
           ++ + + + Y G  Y+G QR P                  + +E   N        + RT
Sbjct: 4   KRNICLKVAYDGTYYHGFQRQPEFHGPTIQGTLEAVWAKLVEEEVTLNT-------AGRT 56

Query: 458 DKGVSAAEQVVSLKLPLEVNVEEI----NKRLPETIKVFAVKRVTNRFNSKSKCNARSYS 625
           D GV AA QVV+ +    + V++I    N  LP  I++ A +     F+++     + Y 
Sbjct: 57  DTGVHAAGQVVNFRTGARIPVDKIPKAFNSLLPRDIRILAAQEAAENFHARFSAKWKRYD 116

Query: 626 YTLPTY 643
           Y +  +
Sbjct: 117 YRIDNH 122


>UniRef50_Q0W2P8 Cluster: Pseudouridylate synthase; n=1; uncultured
           methanogenic archaeon RC-I|Rep: Pseudouridylate synthase
           - Uncultured methanogenic archaeon RC-I
          Length = 266

 Score = 44.4 bits (100), Expect = 0.002
 Identities = 32/119 (26%), Positives = 50/119 (42%), Gaps = 2/119 (1%)
 Frame = +2

Query: 284 KMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTDK 463
           K A+ + Y G  +YG Q  PG+ T+               +E        +   + RTD 
Sbjct: 2   KTALKIAYVGTNFYGSQAQPGLPTVESELRK-------ALEEAGAIKLGTKIAMAGRTDA 54

Query: 464 GVSAAEQVVSLKL--PLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYSYTL 634
           GV A  QVV+ +   P       IN +LP+ +  +A   V + F+ +    +R Y Y L
Sbjct: 55  GVHALGQVVAFEQADPKLTAPRIINSKLPKDLWAYARAEVPDDFDPRRHATSREYRYIL 113


>UniRef50_Q8DWH1 Cluster: tRNA pseudouridine synthase A; n=42;
           Lactobacillales|Rep: tRNA pseudouridine synthase A -
           Streptococcus mutans
          Length = 249

 Score = 44.4 bits (100), Expect = 0.002
 Identities = 28/115 (24%), Positives = 56/115 (48%), Gaps = 4/115 (3%)
 Frame = +2

Query: 296 LLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTDKGVSA 475
           ++ Y G  + G QR P V+T+              T     + Q  +   + RTD GV A
Sbjct: 7   IISYDGTNFSGFQRQPQVRTVQEEIEK--------TLLRLNSGQAVKIHGAGRTDAGVHA 58

Query: 476 AEQVVSLKLPLEVNVEE----INKRLPETIKVFAVKRVTNRFNSKSKCNARSYSY 628
             QV+   LP + ++E+    ++ + P+ I V  V++V + F+++ + + ++Y +
Sbjct: 59  YGQVIHFDLPQQRDLEKLRFGLDTQTPDDIDVIQVEQVADDFHARYQKHRKTYEF 113


>UniRef50_UPI00015B40A8 Cluster: PREDICTED: similar to
           pseudouridylate synthase; n=1; Nasonia vitripennis|Rep:
           PREDICTED: similar to pseudouridylate synthase - Nasonia
           vitripennis
          Length = 421

 Score = 43.6 bits (98), Expect = 0.004
 Identities = 26/87 (29%), Positives = 42/87 (48%), Gaps = 13/87 (14%)
 Frame = +2

Query: 416 ENAQNAQFQRSSRTDKGVSAAEQVVSLKLPLEVNVEE-------------INKRLPETIK 556
           E+ + + + R  RTDKGVSA  QV+SL +   +  E+             +N+ LP+ I+
Sbjct: 112 ESRETSNYHRCGRTDKGVSAFSQVISLDIRSRLEPEKQDNLSDELHYCKMLNRLLPKNIR 171

Query: 557 VFAVKRVTNRFNSKSKCNARSYSYTLP 637
            F+        +++  C  RSY Y  P
Sbjct: 172 CFSWSPAHPEMSARFDCKFRSYKYFFP 198


>UniRef50_A6DAN4 Cluster: Pseudouridylate synthase; n=1;
           Caminibacter mediatlanticus TB-2|Rep: Pseudouridylate
           synthase - Caminibacter mediatlanticus TB-2
          Length = 223

 Score = 43.6 bits (98), Expect = 0.004
 Identities = 25/73 (34%), Positives = 36/73 (49%), Gaps = 4/73 (5%)
 Frame = +2

Query: 428 NAQFQRSSRTDKGVSAAEQVVSLKLP----LEVNVEEINKRLPETIKVFAVKRVTNRFNS 595
           N+  Q + RTDKGV A  QV+S  +P    L      +NK +   I +  +K + N FN 
Sbjct: 24  NSIVQHAGRTDKGVHALNQVISFTIPNFWDLNKLQTSLNKIIHPYIHIKKIKFIKNDFNP 83

Query: 596 KSKCNARSYSYTL 634
           +     RSY Y +
Sbjct: 84  RFNAKKRSYRYII 96


>UniRef50_Q7QV27 Cluster: GLP_180_17283_16483; n=1; Giardia lamblia
           ATCC 50803|Rep: GLP_180_17283_16483 - Giardia lamblia
           ATCC 50803
          Length = 266

 Score = 43.6 bits (98), Expect = 0.004
 Identities = 29/87 (33%), Positives = 40/87 (45%), Gaps = 1/87 (1%)
 Frame = +2

Query: 236 KPPGEIKKPYERIKRKKMAMLLGYSGVEYYGMQRNPGVQ-TIXXXXXXXXXXXXYITQED 412
           KP       +  I  + +A+ + Y G EY G+ + P  + TI             I Q  
Sbjct: 76  KPSSRSLMDWSTIPLRHIAIQVCYDGTEYAGLAQQPNREYTIEELLLNALRGAALIPQH- 134

Query: 413 FENAQNAQFQRSSRTDKGVSAAEQVVS 493
              A +  F+RS RTD+GVSAA QV S
Sbjct: 135 -AEASDVHFERSGRTDRGVSAAGQVFS 160


>UniRef50_O66953 Cluster: tRNA pseudouridine synthase A; n=1;
           Aquifex aeolicus|Rep: tRNA pseudouridine synthase A -
           Aquifex aeolicus
          Length = 241

 Score = 43.6 bits (98), Expect = 0.004
 Identities = 31/116 (26%), Positives = 52/116 (44%), Gaps = 4/116 (3%)
 Frame = +2

Query: 299 LGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTDKGVSAA 478
           L + G  +YG Q  P ++T+             I  ED       +     RTD GV A 
Sbjct: 8   LAFVGTNFYGWQVQPNLRTVQGEIQKALSQ---ILCED------VKVTGCCRTDSGVHAL 58

Query: 479 EQVVSLK----LPLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYSYTL 634
           + + + K     P E  ++ +N  LP+ + V+AVK+V+  FN++     + Y Y +
Sbjct: 59  DYIANFKTQKDFPEEKLLKALNGILPKDVGVYAVKKVSEEFNARYSVKGKVYLYKI 114


>UniRef50_UPI0000E87E98 Cluster: tRNA pseudouridine synthase A; n=1;
           Methylophilales bacterium HTCC2181|Rep: tRNA
           pseudouridine synthase A - Methylophilales bacterium
           HTCC2181
          Length = 264

 Score = 42.7 bits (96), Expect = 0.007
 Identities = 35/122 (28%), Positives = 55/122 (45%), Gaps = 5/122 (4%)
 Frame = +2

Query: 284 KMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSS-RTD 460
           ++A  + Y+G  + G Q+ P V+TI             I     E A++     +S RTD
Sbjct: 2   RIACSVSYNGYGFSGWQKQPDVKTIQGL----------IESALTEIAKDTVITHASGRTD 51

Query: 461 KGVSAAEQVVSLKL----PLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYSY 628
            GV A  Q++        PL   V+ +N  LP +IKV   K ++  F+++     R Y Y
Sbjct: 52  SGVHALGQIIHFDTTKNRPLTAWVKGVNAFLPSSIKVRWAKNISESFHARHSVLEREYQY 111

Query: 629 TL 634
            L
Sbjct: 112 LL 113


>UniRef50_Q1IRQ4 Cluster: Pseudouridylate synthase; n=2;
           Acidobacteria|Rep: Pseudouridylate synthase -
           Acidobacteria bacterium (strain Ellin345)
          Length = 257

 Score = 42.7 bits (96), Expect = 0.007
 Identities = 33/122 (27%), Positives = 50/122 (40%), Gaps = 4/122 (3%)
 Frame = +2

Query: 281 KKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTD 460
           +   + L Y G E++G Q  PG  TI              T E     Q    Q S RTD
Sbjct: 3   RNFKITLAYDGHEFHGWQIQPGKPTIQGTLAE--------TIERITGEQTLP-QGSGRTD 53

Query: 461 KGVSAAEQVVSLKLPLEVNVE----EINKRLPETIKVFAVKRVTNRFNSKSKCNARSYSY 628
            GV A  QV S+ L   +  +     +N +LP +I+   V      F+++     ++Y Y
Sbjct: 54  AGVHALGQVASVALQTPIPADGLHIALNDKLPPSIRALTVGEAAPDFHARHSAKGKTYRY 113

Query: 629 TL 634
            +
Sbjct: 114 RI 115


>UniRef50_A0YB03 Cluster: Pseudouridylate synthase; n=10;
           Gammaproteobacteria|Rep: Pseudouridylate synthase -
           marine gamma proteobacterium HTCC2143
          Length = 288

 Score = 42.7 bits (96), Expect = 0.007
 Identities = 36/123 (29%), Positives = 53/123 (43%), Gaps = 6/123 (4%)
 Frame = +2

Query: 284 KMAMLLGYSGVEYYGMQ--RNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRT 457
           ++A+ + Y G  Y+G Q  R P V T+                    NA N   Q + RT
Sbjct: 27  RVALCVSYDGSAYHGWQSQRKPQVATVQETLEKAL--------SSVANA-NVIVQCAGRT 77

Query: 458 DKGVSAAEQVVSLKLPL----EVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYS 625
           D GV A+ Q+V    P     +  V   N  LP +I +   K V+ +FN++    AR Y 
Sbjct: 78  DTGVHASHQIVHFDSPSARGEKAWVRGGNTNLPSSIAIQWAKPVSAKFNARFSATARRYR 137

Query: 626 YTL 634
           Y +
Sbjct: 138 YVI 140


>UniRef50_Q4D8T5 Cluster: Pseudouridylate synthase I, putative; n=2;
           Trypanosoma cruzi|Rep: Pseudouridylate synthase I,
           putative - Trypanosoma cruzi
          Length = 655

 Score = 42.7 bits (96), Expect = 0.007
 Identities = 28/78 (35%), Positives = 38/78 (48%), Gaps = 9/78 (11%)
 Frame = +2

Query: 437 FQRSSRTDKGVSAAEQVVSLKLPLE--------VNVEE-INKRLPETIKVFAVKRVTNRF 589
           F RS RTD+GV A   +V L +  E          ++E +N  LP TI+V  V  +   F
Sbjct: 79  FSRSCRTDRGVHAVRNLVCLFVFTERIEALGGCEKIKEMLNTTLPLTIRVARVTPLMGNF 138

Query: 590 NSKSKCNARSYSYTLPTY 643
             +  CN R Y Y +P Y
Sbjct: 139 IPRFSCNRRVYHYLIPAY 156


>UniRef50_Q5L3Q7 Cluster: tRNA pseudouridine synthase A; n=11;
           Bacillaceae|Rep: tRNA pseudouridine synthase A -
           Geobacillus kaustophilus
          Length = 258

 Score = 42.7 bits (96), Expect = 0.007
 Identities = 30/124 (24%), Positives = 52/124 (41%), Gaps = 4/124 (3%)
 Frame = +2

Query: 281 KKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTD 460
           +++  ++ Y G  + G Q  PG +T+                         +   S RTD
Sbjct: 3   QRIKCIIAYDGTHFSGYQIQPGKRTVQGEFEEVLRR--------MHKGTKVRVAASGRTD 54

Query: 461 KGVSAAEQVVSLKLPLEVNVEE----INKRLPETIKVFAVKRVTNRFNSKSKCNARSYSY 628
            GV A  QV+    PL ++ E+    +N +LP+ I V  V+     F+++    A+ Y Y
Sbjct: 55  AGVHAYGQVIHFDTPLSLSSEQWKKALNAQLPDDIVVRFVQEADADFHARFSAKAKEYRY 114

Query: 629 TLPT 640
            + T
Sbjct: 115 KVWT 118


>UniRef50_A7PC02 Cluster: Chromosome chr2 scaffold_11, whole genome
           shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
           chr2 scaffold_11, whole genome shotgun sequence - Vitis
           vinifera (Grape)
          Length = 370

 Score = 42.3 bits (95), Expect = 0.010
 Identities = 35/132 (26%), Positives = 57/132 (43%), Gaps = 9/132 (6%)
 Frame = +2

Query: 269 RIKRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQR- 445
           R  R    ++L Y G  + G Q+ PG+ T+               +      +N   +  
Sbjct: 91  RWARLTFKIVLSYHGASFDGWQKQPGLNTVQGLVEASLGRFVDERKAQQLKEKNLPVEGM 150

Query: 446 ---SSRTDKGVSAAEQVVSL---KLPLEV-NVEE-INKRLPETIKVFAVKRVTNRFNSKS 601
              + RTDKGV+A +QV S    K  ++V ++E+ IN   P  ++V +V  V+  F+   
Sbjct: 151 VTVAGRTDKGVTALQQVCSFYTWKKDVKVQDIEDAINGAAPGKLRVISVSEVSRIFHPNF 210

Query: 602 KCNARSYSYTLP 637
               R Y Y  P
Sbjct: 211 SAKWRHYFYIFP 222


>UniRef50_A5E2I9 Cluster: Pseudouridylate synthase; n=4;
           Saccharomycetales|Rep: Pseudouridylate synthase -
           Lodderomyces elongisporus (Yeast) (Saccharomyces
           elongisporus)
          Length = 491

 Score = 42.3 bits (95), Expect = 0.010
 Identities = 29/88 (32%), Positives = 41/88 (46%), Gaps = 17/88 (19%)
 Frame = +2

Query: 416 ENAQNAQFQRSSRTDKGVSAAEQVVSLKLPLEVNVEE----------------INKRLPE 547
           E  +  ++ +  RTDKGVSA  QV+S+KL   +  +E                IN  LP 
Sbjct: 173 EPIEEVEYSKCGRTDKGVSAMNQVISIKLRSNLTPQEQQDPAFDAKEVDYFTVINANLPA 232

Query: 548 TIKVFAV-KRVTNRFNSKSKCNARSYSY 628
            IKV A+  R    F+++  C  R Y Y
Sbjct: 233 DIKVHAICLRPPENFDARFSCKERHYRY 260


>UniRef50_A7I4S8 Cluster: tRNA pseudouridine synthase A; n=1;
           Candidatus Methanoregula boonei 6A8|Rep: tRNA
           pseudouridine synthase A - Methanoregula boonei (strain
           6A8)
          Length = 276

 Score = 42.3 bits (95), Expect = 0.010
 Identities = 28/116 (24%), Positives = 49/116 (42%), Gaps = 1/116 (0%)
 Frame = +2

Query: 284 KMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTDK 463
           ++A  + Y G  +YG Q+    +T+                  F + + A F  + RTD+
Sbjct: 16  RLACRVSYLGTRFYGSQQQESSRTVEGEFIEACRRLAL-----FSDWRTAGFASAGRTDR 70

Query: 464 GVSAAEQVVSLKLPLEVNVEE-INKRLPETIKVFAVKRVTNRFNSKSKCNARSYSY 628
           GV A  QV++          + +N +LP  I   A   V + F+ +    +R+Y Y
Sbjct: 71  GVHACGQVIAFSTQTPDRARQALNSQLPPDIWCTATAVVPDHFHPRYDARSRTYRY 126


>UniRef50_Q6DI24 Cluster: Zgc:56653 protein; n=2; Danio rerio|Rep:
           Zgc:56653 protein - Danio rerio (Zebrafish) (Brachydanio
           rerio)
          Length = 386

 Score = 41.9 bits (94), Expect = 0.013
 Identities = 39/156 (25%), Positives = 69/156 (44%), Gaps = 27/156 (17%)
 Frame = +2

Query: 251 IKKPYE--RIKRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENA 424
           ++KP++     R+ +A+ L Y G +Y G      VQ               +  +  ++ 
Sbjct: 46  VEKPFDFSAHPRRHVALRLAYLGWQYQGF----AVQENTDNTVEARLFEALLKTKLIQDR 101

Query: 425 QNAQFQRSSRTDKGVSAAEQVVSLKL-------------PLEVNVEE------------I 529
           Q + + R  RTDKGVSA  QV+S+ L             P +V+V+             +
Sbjct: 102 QTSCYHRCGRTDKGVSAFSQVISIDLRSTQYGGGLGVTVPADVDVKGKTSADELPYVKIL 161

Query: 530 NKRLPETIKVFAVKRVTNRFNSKSKCNARSYSYTLP 637
           N+ LP+ I++     V + F+++  C +R+Y Y  P
Sbjct: 162 NRVLPQDIRILQWAPVESGFSARFDCQSRTYRYYFP 197


>UniRef50_Q57WP9 Cluster: Pseudouridylate synthase I, putative; n=1;
           Trypanosoma brucei|Rep: Pseudouridylate synthase I,
           putative - Trypanosoma brucei
          Length = 618

 Score = 41.9 bits (94), Expect = 0.013
 Identities = 28/84 (33%), Positives = 40/84 (47%), Gaps = 9/84 (10%)
 Frame = +2

Query: 419 NAQNAQFQRSSRTDKGVSAAEQVVSLKLP---LEVN------VEEINKRLPETIKVFAVK 571
           + +   F RS RTD+GV A   +V L +P   LE         + +N  LP T++V  V 
Sbjct: 73  SGEEHHFARSCRTDRGVHAVRNLVCLFVPNSKLEAAGGCDRLPQLLNAHLPSTVRVERVT 132

Query: 572 RVTNRFNSKSKCNARSYSYTLPTY 643
            V   F  +  C +R Y Y +P Y
Sbjct: 133 TVMGDFIPRFCCVSRIYRYMIPVY 156


>UniRef50_Q6MDE3 Cluster: tRNA pseudouridine synthase A 2; n=1;
           Candidatus Protochlamydia amoebophila UWE25|Rep: tRNA
           pseudouridine synthase A 2 - Protochlamydia amoebophila
           (strain UWE25)
          Length = 262

 Score = 41.9 bits (94), Expect = 0.013
 Identities = 33/140 (23%), Positives = 58/140 (41%), Gaps = 5/140 (3%)
 Frame = +2

Query: 224 DWETKPPGEIKKPYERIKRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYIT 403
           D+ T+    + K  + IK K     + Y G  Y+G Q+ P   ++              T
Sbjct: 2   DYTTQSDLSLSKSMQNIKLK-----IAYDGQAYFGWQKTPAGPSVEKTLQNSLEQILQHT 56

Query: 404 QEDFENAQNAQFQRSSRTDKGVSAAEQVVSLK-----LPLEVNVEEINKRLPETIKVFAV 568
                       Q +SRTDKGV A  Q+V+         L+  +  +N  LP  +++ + 
Sbjct: 57  ---------ISLQAASRTDKGVHARGQIVNFLTTKSITDLQKFILSLNSLLPTDLRILSA 107

Query: 569 KRVTNRFNSKSKCNARSYSY 628
           +++ + F+    C A+ Y Y
Sbjct: 108 EKMPSTFHPTLNCVAKEYCY 127


>UniRef50_Q583N7 Cluster: Pseudouridylate synthase; n=1; Trypanosoma
           brucei|Rep: Pseudouridylate synthase - Trypanosoma
           brucei
          Length = 428

 Score = 41.5 bits (93), Expect = 0.017
 Identities = 40/148 (27%), Positives = 62/148 (41%), Gaps = 15/148 (10%)
 Frame = +2

Query: 230 ETKPPGEIKK-PYERIKRKKMAMLLGYSGVEYYGMQRNPGV-QTIXXXXXXXXXXXXYIT 403
           E KP  + ++  +     +K+A+ L Y G  Y G+ R      T+            ++ 
Sbjct: 7   EGKPRSKERQFDFSSYPSRKIALRLAYHGHIYCGLVRQAETPNTVEAYLVAALERLRFV- 65

Query: 404 QEDFENAQNAQFQRSSRTDKGVSAAEQVVSL-------------KLPLEVNVEEINKRLP 544
               E +    F R  RTDKGVSA   VVS              + PL+   E++N  LP
Sbjct: 66  ----EPSGPKDFSRCGRTDKGVSALGNVVSFTSRASSWATDEQQQPPLDY-CEKLNNVLP 120

Query: 545 ETIKVFAVKRVTNRFNSKSKCNARSYSY 628
            TI++     V   F+++  C  R+Y Y
Sbjct: 121 PTIRIVGWSYVNADFDARFSCTGRTYRY 148


>UniRef50_Q17C60 Cluster: Pseudouridylate synthase; n=2;
           Culicidae|Rep: Pseudouridylate synthase - Aedes aegypti
           (Yellowfever mosquito)
          Length = 467

 Score = 41.5 bits (93), Expect = 0.017
 Identities = 29/91 (31%), Positives = 46/91 (50%), Gaps = 17/91 (18%)
 Frame = +2

Query: 416 ENAQNAQFQRSSRTDKGVSAAEQVVSL---------------KLPLEVN-VEEINKRLPE 547
           EN + + + R  RTDKGVSA  QVVSL                +  E+N  + +N+ LP+
Sbjct: 115 ENRETSNYHRCGRTDKGVSAFHQVVSLDVRSKFAPENQLEPESIANEINYCQLLNRVLPQ 174

Query: 548 TIKVFA-VKRVTNRFNSKSKCNARSYSYTLP 637
            I+  A +  V   ++++  C +R+Y Y  P
Sbjct: 175 DIRCVAWMPMVNPNYSARFDCRSRTYRYFFP 205


>UniRef50_Q7RDA0 Cluster: Putative uncharacterized protein PY05524;
            n=10; Plasmodium (Vinckeia)|Rep: Putative uncharacterized
            protein PY05524 - Plasmodium yoelii yoelii
          Length = 1510

 Score = 41.1 bits (92), Expect = 0.022
 Identities = 16/42 (38%), Positives = 25/42 (59%)
 Frame = +2

Query: 518  VEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYSYTLPTY 643
            ++ +N  LP  IK F + +VT  F+++  C+ R Y Y  PTY
Sbjct: 1219 IKLLNSNLPSDIKCFDIYKVTKSFDARKFCSFRLYEYLFPTY 1260



 Score = 33.1 bits (72), Expect = 5.9
 Identities = 30/121 (24%), Positives = 47/121 (38%), Gaps = 4/121 (3%)
 Frame = +2

Query: 185  KLLTRYNKRRAHRDWETKPPGEIKKPY----ERIKRKKMAMLLGYSGVEYYGMQRNPGVQ 352
            KL    NKRR   D + +  G+ K       +  K KK  + +GY G  Y+G Q   G +
Sbjct: 1032 KLKFERNKRRKEDDEKNEKGGDEKNEKGGDEKNNKFKKYGLCVGYIGSRYHGCQ-GQGKE 1090

Query: 353  TIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTDKGVSAAEQVVSLKLPLEVNVEEIN 532
             +                +      N    RS+RTD GV A   +    + +++   + N
Sbjct: 1091 YMTIENEIERTLTKINAVKKTSKGFNYCLSRSARTDLGVHALYNLFVYNINIDICENDNN 1150

Query: 533  K 535
            K
Sbjct: 1151 K 1151


>UniRef50_Q6C194 Cluster: Pseudouridylate synthase; n=1; Yarrowia
           lipolytica|Rep: Pseudouridylate synthase - Yarrowia
           lipolytica (Candida lipolytica)
          Length = 443

 Score = 41.1 bits (92), Expect = 0.022
 Identities = 27/81 (33%), Positives = 43/81 (53%), Gaps = 17/81 (20%)
 Frame = +2

Query: 437 FQRSSRTDKGVSAAEQVVSLKLPLEVNVEE----------------INKRLPETIKVFAV 568
           F R  RTD+GVSA  QV++LK+  +++ EE                +N+ LP  I++++V
Sbjct: 137 FSRCGRTDRGVSAFSQVIALKVRSKLSPEEQQDAANDNKELNYIHILNQLLPPDIRIYSV 196

Query: 569 K-RVTNRFNSKSKCNARSYSY 628
             R+   F+S+  C  R Y Y
Sbjct: 197 ALRLPEGFDSRFSCEYRHYRY 217


>UniRef50_Q2FT01 Cluster: Pseudouridylate synthase; n=1;
           Methanospirillum hungatei JF-1|Rep: Pseudouridylate
           synthase - Methanospirillum hungatei (strain JF-1 / DSM
           864)
          Length = 276

 Score = 41.1 bits (92), Expect = 0.022
 Identities = 31/116 (26%), Positives = 51/116 (43%), Gaps = 1/116 (0%)
 Frame = +2

Query: 284 KMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTDK 463
           ++A  +GY G  ++G Q  P  +T+             IT     + Q ++   S RTD+
Sbjct: 12  RLAFRIGYIGTSFFGSQYQPDQRTVEGEIEAACLRAGIIT-----SRQVSRLALSGRTDR 66

Query: 464 GVSAAEQVVSLKL-PLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYSY 628
           GV A  Q+++L     ++ V  +N +LP  I V A       F  +     R+Y Y
Sbjct: 67  GVHAKCQILALSTHNPDLAVRALNGQLPPDIWVSAWAYAPESFYPRYDVIIRTYRY 122


>UniRef50_Q9PPV4 Cluster: tRNA pseudouridine synthase A; n=1;
           Ureaplasma parvum|Rep: tRNA pseudouridine synthase A -
           Ureaplasma parvum (Ureaplasma urealyticum biotype 1)
          Length = 241

 Score = 41.1 bits (92), Expect = 0.022
 Identities = 32/120 (26%), Positives = 53/120 (44%), Gaps = 5/120 (4%)
 Frame = +2

Query: 299 LGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTDKGVSAA 478
           L Y G  +YG  R P  +T+             I +  F+   N +   S RTDKGV A 
Sbjct: 7   LRYDGSLFYGWARQPQKRTVQGDLEE-------IFKSIFK-INNIRIIGSGRTDKGVHAY 58

Query: 479 EQVVS-----LKLPLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYSYTLPTY 643
           EQ  S     LK    +  + +  R    I++  V++V + F+++    +++Y Y +  Y
Sbjct: 59  EQTFSVKHSALKYDSHIIYQALCSRTSSDIQILEVQKVDDSFHAQYNATSKTYQYVINDY 118


>UniRef50_Q8TWZ3 Cluster: tRNA pseudouridine synthase A; n=1;
           Methanopyrus kandleri|Rep: tRNA pseudouridine synthase A
           - Methanopyrus kandleri
          Length = 256

 Score = 41.1 bits (92), Expect = 0.022
 Identities = 35/118 (29%), Positives = 52/118 (44%), Gaps = 1/118 (0%)
 Frame = +2

Query: 284 KMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTDK 463
           ++A+ + Y G  Y+G Q  P V TI             +++   E    A     SRTD 
Sbjct: 2   RVALRVAYDGSRYHGFQYQPDVPTIEGALRKA------LSELGLELVGYA-----SRTDA 50

Query: 464 GVSAAEQVVSLKLPLEV-NVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYSYTL 634
           G  A  QVV ++   E+   + IN RLP+ I+V A   V   F+ +     + Y Y L
Sbjct: 51  GAHARYQVVVVEGDPELAQPDPINARLPKDIRVIAKTEVHEEFDPRRDALRKEYRYFL 108


>UniRef50_O28544 Cluster: tRNA pseudouridine synthase A; n=1;
           Archaeoglobus fulgidus|Rep: tRNA pseudouridine synthase
           A - Archaeoglobus fulgidus
          Length = 265

 Score = 41.1 bits (92), Expect = 0.022
 Identities = 29/117 (24%), Positives = 51/117 (43%)
 Frame = +2

Query: 284 KMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTDK 463
           K A  + Y G  ++G Q  P  +T+                      +N + + + RTD 
Sbjct: 3   KFAFKIAYFGDNFHGSQFQPDQRTVEGEVINALRRL---------GVENPRLRSAGRTDA 53

Query: 464 GVSAAEQVVSLKLPLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYSYTL 634
           GV A  QV+S     ++    +N  LPE I  +A  +V+  F+ + +  +R Y+Y +
Sbjct: 54  GVHAYGQVISFYSEDKIFPRMLNAELPEDITAWAWAKVSEDFDPR-RAKSRVYTYVM 109


>UniRef50_Q654A2 Cluster: Pseudouridylate synthase; n=3; Oryza
           sativa|Rep: Pseudouridylate synthase - Oryza sativa
           subsp. japonica (Rice)
          Length = 495

 Score = 40.7 bits (91), Expect = 0.029
 Identities = 33/132 (25%), Positives = 57/132 (43%), Gaps = 9/132 (6%)
 Frame = +2

Query: 269 RIKRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQR- 445
           R +R    ++L Y G  + G Q+ PG+ T+               +     A++   +  
Sbjct: 117 RWERVTFKIVLSYHGGSFDGWQKQPGLNTVQGLVEKHLGQFVDEKKAKQLEARSLPLEGC 176

Query: 446 ---SSRTDKGVSAAEQVVSL----KLPLEVNVEE-INKRLPETIKVFAVKRVTNRFNSKS 601
              + RTDKGV+A +QV S     K     ++++ INK  P+ ++   V +V+  F+   
Sbjct: 177 AVVAGRTDKGVTALQQVCSFYTWRKDVKSSDIKDAINKAAPDKLRPLHVSQVSREFHPNF 236

Query: 602 KCNARSYSYTLP 637
               R Y Y  P
Sbjct: 237 AAKWRRYLYIFP 248


>UniRef50_Q5CPW7 Cluster: Pus1p-like type II pseudousynthas TruA;
           n=2; Cryptosporidium|Rep: Pus1p-like type II
           pseudousynthas TruA - Cryptosporidium parvum Iowa II
          Length = 501

 Score = 40.7 bits (91), Expect = 0.029
 Identities = 19/49 (38%), Positives = 31/49 (63%), Gaps = 1/49 (2%)
 Frame = +2

Query: 500 LPLEVNVEEINKRLPET-IKVFAVKRVTNRFNSKSKCNARSYSYTLPTY 643
           L L+  V ++N+ L  T IKVF + RVT  F++++ C+ R Y Y +P +
Sbjct: 163 LILDYIVTKLNELLESTKIKVFKIFRVTKNFDARTDCSRRQYEYLMPEF 211



 Score = 35.5 bits (78), Expect = 1.1
 Identities = 29/99 (29%), Positives = 41/99 (41%), Gaps = 13/99 (13%)
 Frame = +2

Query: 266 ERIKRKKMAMLLGYSGVEYYGMQ----RNPGVQTIXXXXXXXXXXXXYITQEDFENAQN- 430
           E I  K   M  GY G +Y+GMQ     N  V+ +             +      N QN 
Sbjct: 3   EVIPMKTYCMSFGYDGSDYHGMQIQMRNNKKVEELRTIEGEMEDCLEKLGMFFLSNEQND 62

Query: 431 --------AQFQRSSRTDKGVSAAEQVVSLKLPLEVNVE 523
                    ++ R  RTDKGV +  QVVS +  +++N E
Sbjct: 63  DQGGLLKKIKWSRVGRTDKGVHSVCQVVSFRAKIKINDE 101


>UniRef50_A3LX03 Cluster: Pseudouridylate synthase; n=4;
           Saccharomycetaceae|Rep: Pseudouridylate synthase -
           Pichia stipitis (Yeast)
          Length = 465

 Score = 40.7 bits (91), Expect = 0.029
 Identities = 40/140 (28%), Positives = 60/140 (42%), Gaps = 20/140 (14%)
 Frame = +2

Query: 269 RIKRKKMAMLLGYSGVEYYGM--QRNPG-VQTIXXXXXXXXXXXXYITQEDFENAQNAQF 439
           +  ++ +A+   Y G  Y G+  Q  P  + T+             IT+         +F
Sbjct: 85  KYNKRFIALKFAYLGWNYNGLAYQSEPTPLPTVEEVVLKALTMSRLITEP---TPDKCKF 141

Query: 440 QRSSRTDKGVSAAEQVVSLKLPLEVNVEE----------------INKRLPETIKVFAV- 568
            R  RTDKGVSA  QV+SL +   +N EE                IN  LP  I++ AV 
Sbjct: 142 SRCGRTDKGVSAMNQVISLVVRSNLNEEEQLLKENDHKEIKYLSIINALLPPDIRMTAVC 201

Query: 569 KRVTNRFNSKSKCNARSYSY 628
            R   +F+++  C+ R Y Y
Sbjct: 202 LRPPPKFDARFSCDYRHYRY 221


>UniRef50_A0B7V0 Cluster: Pseudouridylate synthase; n=1;
           Methanosaeta thermophila PT|Rep: Pseudouridylate
           synthase - Methanosaeta thermophila (strain DSM 6194 /
           PT) (Methanothrixthermophila (strain DSM 6194 / PT))
          Length = 267

 Score = 40.7 bits (91), Expect = 0.029
 Identities = 33/121 (27%), Positives = 49/121 (40%), Gaps = 4/121 (3%)
 Frame = +2

Query: 284 KMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTDK 463
           K+A+ + Y G  YYG QR PG++T+                       N  F  + RTD+
Sbjct: 2   KIALKIAYLGDRYYGFQRQPGLRTVESVMRDALLRI---------GVANGDFCYAGRTDR 52

Query: 464 GVSAAEQVVSLKLPLE----VNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYSYT 631
           GVSA  QV+   +  +         IN  LP  +  +A       F+++     R Y Y 
Sbjct: 53  GVSALGQVIDFWIEEDRAYLAFPRVINSLLPSDVWAWARAVAPVGFSARWSALWREYRYF 112

Query: 632 L 634
           L
Sbjct: 113 L 113


>UniRef50_Q057U4 Cluster: Pseudouridylate synthase; n=1; Buchnera
           aphidicola str. Cc (Cinara cedri)|Rep: Pseudouridylate
           synthase - Buchnera aphidicola subsp. Cinara cedri
          Length = 269

 Score = 40.3 bits (90), Expect = 0.039
 Identities = 23/67 (34%), Positives = 37/67 (55%), Gaps = 4/67 (5%)
 Frame = +2

Query: 446 SSRTDKGVSAAEQVVSLKLPLEVNVEE----INKRLPETIKVFAVKRVTNRFNSKSKCNA 613
           + RTDKGV A  Q+V     +  N E     +N  LP+ I V  +K+V++ F+++    +
Sbjct: 47  AGRTDKGVHAITQIVHFSSLIIRNEEVWFTGLNSLLPKNITVLWLKKVSSNFHARFSALS 106

Query: 614 RSYSYTL 634
           RSY Y +
Sbjct: 107 RSYRYII 113


>UniRef50_Q09524 Cluster: Probable tRNA pseudouridine synthase
           tag-124; n=2; Caenorhabditis|Rep: Probable tRNA
           pseudouridine synthase tag-124 - Caenorhabditis elegans
          Length = 402

 Score = 40.3 bits (90), Expect = 0.039
 Identities = 43/146 (29%), Positives = 62/146 (42%), Gaps = 28/146 (19%)
 Frame = +2

Query: 278 RKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRT 457
           R+K+A+   Y G E+ G+ + P  Q              ++     E+     F R  RT
Sbjct: 29  RRKIAIQFFYLGWEHDGLVQQPHTQNTVENHIMQALIKTHL----IEDWTKCDFSRCGRT 84

Query: 458 DKGVS-----AAEQVVSL-----------------KLPLEVNVEEI------NKRLPETI 553
           DKGVS     AA  V SL                 K+  + + EE+      N  LP+TI
Sbjct: 85  DKGVSAFKQTAAMVVRSLCPGDSGVFWSDSTQEHQKVDYKASGEELPYVKMLNGVLPKTI 144

Query: 554 KVFAVKRVTNRFNSKSKCNARSYSYT 631
           +VFA   V   FN++  CN R+Y Y+
Sbjct: 145 RVFAWAPVAQTFNARFDCNRRTYKYS 170


>UniRef50_A4XKB7 Cluster: Pseudouridylate synthase; n=3;
           Clostridiales|Rep: Pseudouridylate synthase -
           Caldicellulosiruptor saccharolyticus (strain ATCC 43494
           / DSM 8903)
          Length = 244

 Score = 39.9 bits (89), Expect = 0.051
 Identities = 29/122 (23%), Positives = 51/122 (41%), Gaps = 4/122 (3%)
 Frame = +2

Query: 281 KKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTD 460
           + + + + Y G  Y+G Q+ P  +T+             IT ED           S RTD
Sbjct: 2   RNILLTIEYDGTNYFGWQKQPNKKTVQGVIEDAIKK---ITGED------VNLVGSGRTD 52

Query: 461 KGVSAAEQVVSLKLPLEVNVEE----INKRLPETIKVFAVKRVTNRFNSKSKCNARSYSY 628
           +GV A  Q  + K   ++  E+    +N  LP  I +     V+  F+++     ++Y Y
Sbjct: 53  RGVHALGQKANFKTESKIPTEKFPLALNSVLPNDISIKDAAEVSLDFSARYSAKQKTYKY 112

Query: 629 TL 634
            +
Sbjct: 113 LI 114


>UniRef50_Q8CWM6 Cluster: tRNA pseudouridine synthase A; n=1;
           Synechococcus elongatus|Rep: tRNA pseudouridine synthase
           A - Synechococcus elongatus (Thermosynechococcus
           elongatus)
          Length = 284

 Score = 39.9 bits (89), Expect = 0.051
 Identities = 34/126 (26%), Positives = 59/126 (46%), Gaps = 6/126 (4%)
 Frame = +2

Query: 281 KKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQN--AQFQRSSR 454
           +++A+L+ Y G  ++G QR  G +T+             + ++   +  N       + R
Sbjct: 12  QRLALLIQYQGTHFHGWQRQVGQRTVQE-----------VIEQAIASVVNHPVSVVAAGR 60

Query: 455 TDKGVSAAEQV--VSLKLPLEVNVEE--INKRLPETIKVFAVKRVTNRFNSKSKCNARSY 622
           TD GV AA QV  V++  P+ V+     +N RLP  + + A   V   ++++     R Y
Sbjct: 61  TDTGVHAAGQVAHVTVNSPIPVHRWPGILNARLPADVVIRAAAAVPPDWHARFSALWRRY 120

Query: 623 SYTLPT 640
            YTL T
Sbjct: 121 RYTLYT 126


>UniRef50_P31115 Cluster: tRNA pseudouridine synthase 3; n=5;
           Saccharomycetales|Rep: tRNA pseudouridine synthase 3 -
           Saccharomyces cerevisiae (Baker's yeast)
          Length = 442

 Score = 39.9 bits (89), Expect = 0.051
 Identities = 29/85 (34%), Positives = 43/85 (50%), Gaps = 17/85 (20%)
 Frame = +2

Query: 425 QNAQFQRSSRTDKGVSAAEQVVSLKLPLEVNVEE----------------INKRLPETIK 556
           Q+ +F R  RTDKGVSA  QV+SL++   +  EE                +N+ LP+ I+
Sbjct: 140 QDYKFSRCGRTDKGVSAMNQVISLEVRSNLTDEEQRDPTNDSREIPYVHVLNQLLPDDIR 199

Query: 557 VFAV-KRVTNRFNSKSKCNARSYSY 628
           + AV  R    F+++  C  R Y Y
Sbjct: 200 ISAVCLRPPPNFDARFSCVHRHYKY 224


>UniRef50_Q820P8 Cluster: tRNA pseudouridine synthase A; n=10;
           Proteobacteria|Rep: tRNA pseudouridine synthase A -
           Nitrosomonas europaea
          Length = 272

 Score = 39.5 bits (88), Expect = 0.067
 Identities = 32/121 (26%), Positives = 48/121 (39%), Gaps = 4/121 (3%)
 Frame = +2

Query: 284 KMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTDK 463
           K+ + L Y G  Y G Q+ PG  ++                      +  Q   + RTD 
Sbjct: 13  KIVLALEYDGRGYCGWQKQPGCLSVQSRLESALSGVA---------GRQIQVVAAGRTDA 63

Query: 464 GVSAAEQVVSL----KLPLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYSYT 631
           GV A  QVV L    + PL   +   N  LP  I +     V++ F+++     R+Y Y 
Sbjct: 64  GVHALCQVVHLETCVRRPLNAWIRGTNALLPGDISILEASEVSDDFHARFSATERTYLYY 123

Query: 632 L 634
           L
Sbjct: 124 L 124


>UniRef50_Q88XU9 Cluster: tRNA pseudouridine synthase A; n=10;
           Lactobacillales|Rep: tRNA pseudouridine synthase A -
           Lactobacillus plantarum
          Length = 262

 Score = 39.5 bits (88), Expect = 0.067
 Identities = 31/116 (26%), Positives = 48/116 (41%), Gaps = 4/116 (3%)
 Frame = +2

Query: 293 MLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTDKGVS 472
           ++L Y G  + G QR P  +T+             + +   +  +      + RTD GV 
Sbjct: 7   VVLAYDGTNFAGFQRQPHQRTVEQVVTKA------VNKMAKDPVEPIVIYGAGRTDAGVH 60

Query: 473 AAEQVVSLKLPLEVNVEEI----NKRLPETIKVFAVKRVTNRFNSKSKCNARSYSY 628
           A  Q +   LP E+N E +    N  LP    V AV  V N F+++     + Y Y
Sbjct: 61  AFGQTLHFDLPYEINPEGVRRGLNSMLPMDTIVKAVSIVPNDFHARYDTVGKRYWY 116


>UniRef50_Q3ZZP4 Cluster: Pseudouridylate synthase; n=3;
           Dehalococcoides|Rep: Pseudouridylate synthase -
           Dehalococcoides sp. (strain CBDB1)
          Length = 246

 Score = 39.1 bits (87), Expect = 0.089
 Identities = 26/73 (35%), Positives = 36/73 (49%), Gaps = 4/73 (5%)
 Frame = +2

Query: 422 AQNAQFQRSSRTDKGVSAAEQVVSLKLPLEVNVEEI----NKRLPETIKVFAVKRVTNRF 589
           ++  +   S RTD GV AA QVVS      + +E+I    N  LP  I V  V  V   F
Sbjct: 35  SEQTRVSGSGRTDAGVHAAYQVVSYLTESSLGLEKIKGGLNYYLPPDIAVKEVHFVAENF 94

Query: 590 NSKSKCNARSYSY 628
           + + +  +R YSY
Sbjct: 95  DVRRRAISREYSY 107


>UniRef50_Q3Y386 Cluster: Pseudouridylate synthase; n=3;
           Firmicutes|Rep: Pseudouridylate synthase - Enterococcus
           faecium DO
          Length = 246

 Score = 39.1 bits (87), Expect = 0.089
 Identities = 21/65 (32%), Positives = 33/65 (50%), Gaps = 4/65 (6%)
 Frame = +2

Query: 446 SSRTDKGVSAAEQVVSLKLPLEVNVEEI----NKRLPETIKVFAVKRVTNRFNSKSKCNA 613
           S RTD G  A  QV + K   E+ + E+    N+ LP  I +  ++ +  RF+S+     
Sbjct: 49  SGRTDAGTHARGQVANFKTNTEIGLAEMIDFMNRYLPRDIVIKRIEEMPERFHSRYNAVG 108

Query: 614 RSYSY 628
           + YSY
Sbjct: 109 KKYSY 113


>UniRef50_Q8GUL5 Cluster: Putative uncharacterized protein
           At5g35400; n=1; Arabidopsis thaliana|Rep: Putative
           uncharacterized protein At5g35400 - Arabidopsis thaliana
           (Mouse-ear cress)
          Length = 420

 Score = 39.1 bits (87), Expect = 0.089
 Identities = 32/132 (24%), Positives = 56/132 (42%), Gaps = 9/132 (6%)
 Frame = +2

Query: 269 RIKRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQR- 445
           R +R    ++L Y+G  + G Q+ P + T+               +      +    +  
Sbjct: 89  RWERVNFKIVLSYNGASFDGWQKQPDLHTVQGVVEKSLGGFVDERKAQLLKKKCKPLEGR 148

Query: 446 ---SSRTDKGVSAAEQVVSL---KLPLE-VNVEE-INKRLPETIKVFAVKRVTNRFNSKS 601
              + RTDKGVSA  QV S    +  +E + +E+ INK     ++V ++ +V+  F+   
Sbjct: 149 VLVAGRTDKGVSALNQVCSFYTWRKDIEPIAIEDAINKDASGKLRVVSISKVSRSFHPNF 208

Query: 602 KCNARSYSYTLP 637
               R Y Y  P
Sbjct: 209 SAKWRRYLYIFP 220


>UniRef50_Q8I0W4 Cluster: TRNA pseudouridine synthase, putative;
           n=6; Plasmodium|Rep: TRNA pseudouridine synthase,
           putative - Plasmodium falciparum (isolate 3D7)
          Length = 304

 Score = 39.1 bits (87), Expect = 0.089
 Identities = 25/73 (34%), Positives = 41/73 (56%), Gaps = 11/73 (15%)
 Frame = +2

Query: 443 RSSRTDKGVSAAEQVVSLKLPLEVN-----------VEEINKRLPETIKVFAVKRVTNRF 589
           R SRTDKGVSA    ++L+L ++             V+E+ K+L + I +  +K V+N F
Sbjct: 46  RVSRTDKGVSARINGINLRLNIKYENVPIFEIEKKYVKELKKKL-KNIHIHDIKHVSNTF 104

Query: 590 NSKSKCNARSYSY 628
           +++  C  R+Y Y
Sbjct: 105 DARLNCIQRTYVY 117


>UniRef50_Q22RZ3 Cluster: TRNA pseudouridine synthase family
           protein; n=1; Tetrahymena thermophila SB210|Rep: TRNA
           pseudouridine synthase family protein - Tetrahymena
           thermophila SB210
          Length = 484

 Score = 39.1 bits (87), Expect = 0.089
 Identities = 23/77 (29%), Positives = 39/77 (50%), Gaps = 2/77 (2%)
 Frame = +2

Query: 284 KMAMLLGYSGVEYYGMQ--RNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRT 457
           K+A+  GY+G  Y+G Q  ++  ++TI             I++      + A + R +RT
Sbjct: 12  KVAIFFGYNGKGYHGSQSQKDQNIKTIEKSLFEGLIDSKLISETHMGELKKAGWGRGART 71

Query: 458 DKGVSAAEQVVSLKLPL 508
           DKGV A    V++KL +
Sbjct: 72  DKGVHALCNGVNVKLAI 88


>UniRef50_A3CXX4 Cluster: Pseudouridylate synthase; n=1;
           Methanoculleus marisnigri JR1|Rep: Pseudouridylate
           synthase - Methanoculleus marisnigri (strain ATCC 35101
           / DSM 1498 / JR1)
          Length = 270

 Score = 39.1 bits (87), Expect = 0.089
 Identities = 30/115 (26%), Positives = 48/115 (41%), Gaps = 1/115 (0%)
 Frame = +2

Query: 287 MAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTDKG 466
           +A    Y G  ++G Q  P + T+                  F++ + A F  + RTD+G
Sbjct: 3   LAFRFSYFGDRFFGSQMQPDLCTVEGEFIGACRLLRL-----FDDWREANFATAGRTDRG 57

Query: 467 VSAAEQVVS-LKLPLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYSY 628
           V A  QV S L    E  +E +N+ LP  I         + F+ +    +R+Y Y
Sbjct: 58  VHARSQVCSFLTDKPERAIEALNRVLPADIWCTGWAEAPDGFHPRYSAVSRTYRY 112


>UniRef50_Q9X1R0 Cluster: tRNA pseudouridine synthase A; n=5;
           Thermotogaceae|Rep: tRNA pseudouridine synthase A -
           Thermotoga maritima
          Length = 245

 Score = 39.1 bits (87), Expect = 0.089
 Identities = 33/125 (26%), Positives = 55/125 (44%), Gaps = 5/125 (4%)
 Frame = +2

Query: 281 KKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTD 460
           K++A ++ Y G  ++G Q  P V+T+               +  F+  Q    Q + RTD
Sbjct: 2   KRVAAVIEYDGSNFFGYQGQPDVRTVQGVIEDAL-------ERIFK--QRIYTQAAGRTD 52

Query: 461 KGVSAAEQVVSLKLPLE-VNVEEI----NKRLPETIKVFAVKRVTNRFNSKSKCNARSYS 625
            GV A  Q+++   P + +  E+I    N  LP+ + V  V  V   F+ +     R Y 
Sbjct: 53  TGVHANGQLIAFNCPNDRMTTEDIRNAMNANLPDDVYVKEVFEVPVNFHPRFDVTKRIYH 112

Query: 626 YTLPT 640
           Y + T
Sbjct: 113 YFILT 117


>UniRef50_UPI00015653AF Cluster: tRNA-pseudouridine synthase A; n=1;
           Symbiobacterium thermophilum IAM 14863|Rep:
           tRNA-pseudouridine synthase A - Symbiobacterium
           thermophilum IAM 14863
          Length = 267

 Score = 38.7 bits (86), Expect = 0.12
 Identities = 33/121 (27%), Positives = 50/121 (41%), Gaps = 4/121 (3%)
 Frame = +2

Query: 281 KKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTD 460
           + + ++L Y G  Y G QR P   TI             +T E       A    + RTD
Sbjct: 2   RTIKLILAYDGTAYAGFQRQPNGITIQQRLEEALRA---VTGEPDLRIGAA----AGRTD 54

Query: 461 KGVSAAEQVVSLK----LPLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYSY 628
            GV A  QVV L+    +P++     +N  LP+ I V   +     F+++     + Y Y
Sbjct: 55  AGVHARGQVVHLRTYATIPIDRWPAALNGHLPDDIAVIGAEEAPPDFHARYWAREKRYRY 114

Query: 629 T 631
           T
Sbjct: 115 T 115


>UniRef50_UPI000049A0B0 Cluster: pseudouridine synthase; n=1;
           Entamoeba histolytica HM-1:IMSS|Rep: pseudouridine
           synthase - Entamoeba histolytica HM-1:IMSS
          Length = 366

 Score = 38.7 bits (86), Expect = 0.12
 Identities = 38/145 (26%), Positives = 59/145 (40%), Gaps = 23/145 (15%)
 Frame = +2

Query: 263 YERIKRKKMAMLLGYSGVEYYGMQ---RNPGVQTIXXXXXXXXXXXXYITQEDF-----E 418
           +   K + +A+ L Y G++Y G+Q    N                   + +  F     +
Sbjct: 30  FNNYKTRHIAIRLTYIGIDYNGIQCTLLNDVTDATFDSVINDGTIEYQLFKALFKTRLIQ 89

Query: 419 NAQNAQFQRSSRTDKGVSAAEQVVSLKLPLEVNVEEI---------------NKRLPETI 553
           N ++ ++ R  RTDKGVSA  QVV L +   +  E I               N  LP  I
Sbjct: 90  NTKDCKYNRCGRTDKGVSAFGQVVDLWVRSNLKDETILYTKREGELDYCRMLNGLLPTDI 149

Query: 554 KVFAVKRVTNRFNSKSKCNARSYSY 628
           +      V + FNS+  C +R+Y Y
Sbjct: 150 RCLGWCGVPDDFNSRFSCQSRTYHY 174


>UniRef50_Q8IAP2 Cluster: Putative uncharacterized protein
           PF08_0123; n=1; Plasmodium falciparum 3D7|Rep: Putative
           uncharacterized protein PF08_0123 - Plasmodium
           falciparum (isolate 3D7)
          Length = 530

 Score = 38.7 bits (86), Expect = 0.12
 Identities = 30/99 (30%), Positives = 44/99 (44%), Gaps = 6/99 (6%)
 Frame = +2

Query: 197 RYNKRRAHRDWETKPPGEIKKPYERIKR-----KKMAMLLGYSGVEYYGMQ-RNPGVQTI 358
           R  K +  R    K   E K+ YE  ++     KK A+ +GY G +Y+G Q +    +TI
Sbjct: 18  RIKKLKLERQAIKKKEEEGKEKYENEEKNNLNLKKYALCIGYIGSQYHGCQGQGENCETI 77

Query: 359 XXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTDKGVSA 475
                        I ++ F    N    RS+RTD+GV A
Sbjct: 78  ENTLERTLLKINAIKKKKFFKNFNFCLSRSARTDQGVHA 116



 Score = 37.1 bits (82), Expect = 0.36
 Identities = 15/39 (38%), Positives = 22/39 (56%)
 Frame = +2

Query: 527 INKRLPETIKVFAVKRVTNRFNSKSKCNARSYSYTLPTY 643
           +N  LP  IK F + +VT  F+++  C+ R Y Y  P Y
Sbjct: 223 LNDHLPCDIKCFKIYKVTKSFDARKFCSFRFYEYLFPVY 261


>UniRef50_Q4Q7E9 Cluster: Pseudouridylate synthase; n=5;
           Trypanosomatidae|Rep: Pseudouridylate synthase -
           Leishmania major
          Length = 498

 Score = 38.7 bits (86), Expect = 0.12
 Identities = 34/134 (25%), Positives = 53/134 (39%), Gaps = 12/134 (8%)
 Frame = +2

Query: 263 YERIKRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQ 442
           ++R   +K+A+ L Y G  + G+ +                    +  ED  +     F 
Sbjct: 54  FDRYPSRKIALRLAYHGHVHDGLAKQKETDNTVEGLVCDALRRLRLIPEDGPH----NFG 109

Query: 443 RSSRTDKGVSAAEQVVSL------------KLPLEVNVEEINKRLPETIKVFAVKRVTNR 586
           R  RTDKGVSA     SL            +LP       +N  LP TI++     V + 
Sbjct: 110 RCGRTDKGVSALGNAFSLTARASCTGDAEPQLPPLDYCSMLNNVLPSTIRIVGCALVDDA 169

Query: 587 FNSKSKCNARSYSY 628
           F+++  C  R+Y Y
Sbjct: 170 FDARFSCVHRTYRY 183


>UniRef50_Q64XV0 Cluster: tRNA pseudouridine synthase A; n=16;
           Bacteroidetes|Rep: tRNA pseudouridine synthase A -
           Bacteroides fragilis
          Length = 252

 Score = 38.7 bits (86), Expect = 0.12
 Identities = 24/70 (34%), Positives = 38/70 (54%), Gaps = 5/70 (7%)
 Frame = +2

Query: 446 SSRTDKGVSAAEQVVSLKL---PLEVN--VEEINKRLPETIKVFAVKRVTNRFNSKSKCN 610
           + RTD GV A+  V        PL+V+   E++N+ LP+ I V+ V RV    +++    
Sbjct: 50  AGRTDAGVHASLMVAHFDYEGEPLDVDKVAEKLNRLLPQDISVYKVCRVKPDAHARFDAT 109

Query: 611 ARSYSYTLPT 640
           AR+Y Y + T
Sbjct: 110 ARTYKYYITT 119


>UniRef50_Q3A9U9 Cluster: Pseudouridylate synthase; n=1;
           Carboxydothermus hydrogenoformans Z-2901|Rep:
           Pseudouridylate synthase - Carboxydothermus
           hydrogenoformans (strain Z-2901 / DSM 6008)
          Length = 246

 Score = 38.3 bits (85), Expect = 0.16
 Identities = 22/67 (32%), Positives = 34/67 (50%), Gaps = 4/67 (5%)
 Frame = +2

Query: 446 SSRTDKGVSAAEQVVSLKLPLEVNVEEI----NKRLPETIKVFAVKRVTNRFNSKSKCNA 613
           + RTD GV A  QVV+   P +  V++I    N  LP  I+V   + V + F+++     
Sbjct: 52  AGRTDAGVHALGQVVNFSAPWKAPVDKIPEILNNTLPTAIRVLEAEIVPDDFHARYSARK 111

Query: 614 RSYSYTL 634
           + Y Y L
Sbjct: 112 KEYRYYL 118


>UniRef50_Q08Z59 Cluster: Pseudouridylate synthase; n=2;
           Cystobacterineae|Rep: Pseudouridylate synthase -
           Stigmatella aurantiaca DW4/3-1
          Length = 303

 Score = 38.3 bits (85), Expect = 0.16
 Identities = 34/123 (27%), Positives = 50/123 (40%), Gaps = 4/123 (3%)
 Frame = +2

Query: 272 IKRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSS 451
           +KR    + L Y G  ++G QR P   T+                        A    + 
Sbjct: 24  LKRLSTTLWLWYRGGGFHGFQRQPEGPTVQSTLEAVLR----------STGVPATVMPAG 73

Query: 452 RTDKGVSAAEQVVSLKLPLEVNVEEINKRLPETIK----VFAVKRVTNRFNSKSKCNARS 619
           RTD+GV A  QVVSL+L      E +  RLP  +     V AV+R    F+++     ++
Sbjct: 74  RTDRGVHARMQVVSLRLEAGDTPEALAARLPALLPPDLGVCAVRRPPPSFHAQWSAAGKT 133

Query: 620 YSY 628
           Y Y
Sbjct: 134 YCY 136


>UniRef50_Q7MBB9 Cluster: tRNA pseudouridine synthase A; n=1;
           Gloeobacter violaceus|Rep: tRNA pseudouridine synthase A
           - Gloeobacter violaceus
          Length = 304

 Score = 38.3 bits (85), Expect = 0.16
 Identities = 32/121 (26%), Positives = 55/121 (45%), Gaps = 4/121 (3%)
 Frame = +2

Query: 284 KMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTDK 463
           ++A+ + Y G  ++G Q  PG +T+              T+    +    ++  + RTD 
Sbjct: 16  RLALRVQYLGGHFFGWQWQPGQRTVQQCLEEA-------TERIARHP--VRYHAAGRTDT 66

Query: 464 GVSAAEQVVSL----KLPLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYSYT 631
           GV A+ QVV      KL  E  V  +N  LP+ I V A   V++ ++++     R Y Y 
Sbjct: 67  GVHASGQVVHFDTHKKLAPETWVRGLNSLLPDDIAVRAAAYVSDHWHARFTALWREYRYC 126

Query: 632 L 634
           +
Sbjct: 127 I 127


>UniRef50_Q9BZE2 Cluster: tRNA pseudouridine synthase 3; n=19;
           Euteleostomi|Rep: tRNA pseudouridine synthase 3 - Homo
           sapiens (Human)
          Length = 481

 Score = 38.3 bits (85), Expect = 0.16
 Identities = 31/97 (31%), Positives = 45/97 (46%), Gaps = 23/97 (23%)
 Frame = +2

Query: 416 ENAQNAQFQRSSRTDKGVSAAEQVVSLKL---------PLEVNVEE-------------- 526
           E+ Q + + R  RTDKGVSA  QV+SL L           + NV+E              
Sbjct: 104 ESRQTSNYHRCGRTDKGVSAFGQVISLDLRSQFPRGRDSEDFNVKEEANAAAEEIRYTHI 163

Query: 527 INKRLPETIKVFAVKRVTNRFNSKSKCNARSYSYTLP 637
           +N+ LP  I++ A   V   F+++  C  R+Y Y  P
Sbjct: 164 LNRVLPPDIRILAWAPVEPSFSARFSCLERTYRYFFP 200


>UniRef50_A6Q408 Cluster: Pseudouridylate synthase; n=2;
           unclassified Epsilonproteobacteria|Rep: Pseudouridylate
           synthase - Nitratiruptor sp. (strain SB155-2)
          Length = 241

 Score = 37.9 bits (84), Expect = 0.21
 Identities = 24/68 (35%), Positives = 34/68 (50%), Gaps = 5/68 (7%)
 Frame = +2

Query: 446 SSRTDKGVSAAEQVVSLKLP-----LEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCN 610
           S RTDKGV A  QV+   LP     LE     +N+ L   I++  V +V   F+++    
Sbjct: 47  SGRTDKGVHATAQVIHFDLPPFWSELERLQNLLNESLRPYIQIKRVVKVPKEFHARYSAK 106

Query: 611 ARSYSYTL 634
            R+Y Y L
Sbjct: 107 RRAYRYLL 114


>UniRef50_A5KCH3 Cluster: Pseudouridylate synthase 1, putative; n=1;
           Plasmodium vivax|Rep: Pseudouridylate synthase 1,
           putative - Plasmodium vivax
          Length = 587

 Score = 37.9 bits (84), Expect = 0.21
 Identities = 15/37 (40%), Positives = 23/37 (62%)
 Frame = +2

Query: 527 INKRLPETIKVFAVKRVTNRFNSKSKCNARSYSYTLP 637
           +N+ LPE I+ F + RVT  F+++  C+ R Y Y  P
Sbjct: 191 LNEHLPEDIRCFDMHRVTKSFDARKFCSFRLYEYLFP 227


>UniRef50_Q8R7Y7 Cluster: tRNA pseudouridine synthase A; n=9;
           Clostridia|Rep: tRNA pseudouridine synthase A -
           Thermoanaerobacter tengcongensis
          Length = 240

 Score = 37.9 bits (84), Expect = 0.21
 Identities = 21/67 (31%), Positives = 34/67 (50%), Gaps = 4/67 (5%)
 Frame = +2

Query: 446 SSRTDKGVSAAEQVVSLKLPLEVNVEEI----NKRLPETIKVFAVKRVTNRFNSKSKCNA 613
           SSRTD GV A  QV + K   ++  E++    N  LP+ + V   K V   F+++    +
Sbjct: 44  SSRTDTGVHALYQVANFKTKTKIPPEKLPYALNAVLPDDVVVVKAKEVDKSFHARYSARS 103

Query: 614 RSYSYTL 634
           + Y Y +
Sbjct: 104 KRYRYLI 110


>UniRef50_Q7TU07 Cluster: tRNA pseudouridine synthase A; n=1;
           Pirellula sp.|Rep: tRNA pseudouridine synthase A -
           Rhodopirellula baltica
          Length = 276

 Score = 37.9 bits (84), Expect = 0.21
 Identities = 24/66 (36%), Positives = 33/66 (50%), Gaps = 5/66 (7%)
 Frame = +2

Query: 446 SSRTDKGVSAAEQVVSLKLPL----EVNVEE-INKRLPETIKVFAVKRVTNRFNSKSKCN 610
           S RTD GV A  QV    LP+     V ++  IN +LP  I+V AV+    RF+  +   
Sbjct: 54  SGRTDAGVHAIGQVARCVLPVWKADTVALQRAINSKLPNDIRVKAVRETRERFHPIADAT 113

Query: 611 ARSYSY 628
            + Y Y
Sbjct: 114 GKQYQY 119


>UniRef50_Q4AHD2 Cluster: TRNA pseudouridine synthase; n=1;
           Chlorobium phaeobacteroides BS1|Rep: TRNA pseudouridine
           synthase - Chlorobium phaeobacteroides BS1
          Length = 240

 Score = 37.5 bits (83), Expect = 0.27
 Identities = 20/68 (29%), Positives = 38/68 (55%), Gaps = 5/68 (7%)
 Frame = +2

Query: 452 RTDKGVSAAEQVVSLKLP-LEVNVEEI----NKRLPETIKVFAVKRVTNRFNSKSKCNAR 616
           RTD GV A      + +P +E N+ ++    N+ LP+ + V+ ++ V +  +S+   N+R
Sbjct: 55  RTDTGVHARAFYAHIDIPAIESNLNDLVYKLNRFLPDDLVVYFIQEVPHDLHSRFSANSR 114

Query: 617 SYSYTLPT 640
           +Y Y + T
Sbjct: 115 TYKYYIST 122


>UniRef50_Q11XU3 Cluster: Pseudouridylate synthase; n=1; Cytophaga
           hutchinsonii ATCC 33406|Rep: Pseudouridylate synthase -
           Cytophaga hutchinsonii (strain ATCC 33406 / NCIMB 9469)
          Length = 248

 Score = 37.5 bits (83), Expect = 0.27
 Identities = 30/117 (25%), Positives = 52/117 (44%), Gaps = 5/117 (4%)
 Frame = +2

Query: 299 LGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQ--RSSRTDKGVS 472
           + Y G  Y+G Q      T+             + Q+   N   A+     S RTD GV 
Sbjct: 7   ISYRGANYHGWQIQENAVTVQG-----------VLQKALSNVLGAKIDILGSGRTDTGVH 55

Query: 473 AAEQVVSLKLPLEVN---VEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYSYTL 634
           A+ Q+V L  P E++   +  IN  LP+ I + + + V +  +++    +R+Y Y +
Sbjct: 56  ASSQIVHLDSPKEIDAALIFRINGYLPKDICIKSARLVQDDAHARFDALSRAYVYRI 112


>UniRef50_A6TWE8 Cluster: Pseudouridylate synthase; n=4;
           Clostridia|Rep: Pseudouridylate synthase - Alkaliphilus
           metalliredigens QYMF
          Length = 255

 Score = 37.1 bits (82), Expect = 0.36
 Identities = 21/67 (31%), Positives = 32/67 (47%), Gaps = 4/67 (5%)
 Frame = +2

Query: 446 SSRTDKGVSAAEQVVSLKLPLEVNVEEI----NKRLPETIKVFAVKRVTNRFNSKSKCNA 613
           S RTD GV A  QV S +L  ++  E I    N +LP  I +   K +   F+++     
Sbjct: 48  SGRTDAGVHAQGQVASFQLHSKIPAERISFALNGKLPRDITILEAKEMPEDFHARYSAIG 107

Query: 614 RSYSYTL 634
           + Y Y +
Sbjct: 108 KRYGYCI 114


>UniRef50_A3I2E1 Cluster: TRNA pseudouridine synthase A; n=1;
           Algoriphagus sp. PR1|Rep: TRNA pseudouridine synthase A
           - Algoriphagus sp. PR1
          Length = 233

 Score = 37.1 bits (82), Expect = 0.36
 Identities = 22/65 (33%), Positives = 34/65 (52%), Gaps = 4/65 (6%)
 Frame = +2

Query: 446 SSRTDKGVSAAEQVVSLKLPLEVNVE----EINKRLPETIKVFAVKRVTNRFNSKSKCNA 613
           +SRTD GVS     V + L  EV ++    + N+ LP+ I + +VK V+  FN       
Sbjct: 12  ASRTDSGVSCVGGFVQVFLRDEVEMDLLLPQFNEHLPQDIHLNSVKEVSTTFNLIQSVKK 71

Query: 614 RSYSY 628
           ++Y Y
Sbjct: 72  KTYRY 76


>UniRef50_Q7M9U3 Cluster: tRNA pseudouridine synthase A; n=2;
           Wolinella succinogenes|Rep: tRNA pseudouridine synthase
           A - Wolinella succinogenes
          Length = 253

 Score = 37.1 bits (82), Expect = 0.36
 Identities = 21/68 (30%), Positives = 37/68 (54%), Gaps = 5/68 (7%)
 Frame = +2

Query: 446 SSRTDKGVSAAEQVVSLKLPLEVN-----VEEINKRLPETIKVFAVKRVTNRFNSKSKCN 610
           S RTD+GV A  Q VS ++P + +      EE+NK+L   ++V  +  +    + + +  
Sbjct: 47  SGRTDRGVHATRQAVSFEVPYKKSDWGYFKEELNKKLFPYLRVRRLYPIREGLDPRFEAK 106

Query: 611 ARSYSYTL 634
           +R+Y Y L
Sbjct: 107 SRAYRYLL 114


>UniRef50_Q72DL8 Cluster: tRNA pseudouridine synthase A; n=2;
           Desulfovibrio vulgaris subsp. vulgaris|Rep: tRNA
           pseudouridine synthase A - Desulfovibrio vulgaris
           (strain Hildenborough / ATCC 29579 / NCIMB8303)
          Length = 297

 Score = 37.1 bits (82), Expect = 0.36
 Identities = 22/74 (29%), Positives = 40/74 (54%), Gaps = 4/74 (5%)
 Frame = +2

Query: 425 QNAQFQRSSRTDKGVSAAEQVVSLKLP---LEVNVEE-INKRLPETIKVFAVKRVTNRFN 592
           +  +   + RTD GV A  QV  + +P   L V+ ++ IN +LP+ I +  V+R  + F+
Sbjct: 46  EQVRLHAAGRTDAGVHADGQVAHVDIPDHKLGVDWQKAINAQLPDDICILDVRRAADDFH 105

Query: 593 SKSKCNARSYSYTL 634
           ++     + Y+Y L
Sbjct: 106 ARFDALGKRYTYRL 119


>UniRef50_Q890R5 Cluster: tRNA pseudouridine synthase A 2; n=11;
           Clostridium|Rep: tRNA pseudouridine synthase A 2 -
           Clostridium tetani
          Length = 248

 Score = 37.1 bits (82), Expect = 0.36
 Identities = 22/67 (32%), Positives = 33/67 (49%), Gaps = 4/67 (5%)
 Frame = +2

Query: 446 SSRTDKGVSAAEQVVSLK----LPLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNA 613
           SSRTD GV A     + K    +P E     +N+ LPE I +   + V   F+S+  C  
Sbjct: 51  SSRTDAGVHALAYTANFKTCSTIPGEKFKHALNRFLPEDIVILESEEVPMEFHSRFDCIG 110

Query: 614 RSYSYTL 634
           ++Y Y +
Sbjct: 111 KTYVYKI 117


>UniRef50_Q6I3T8 Cluster: tRNA pseudouridine synthase A 2; n=12;
           Bacillus|Rep: tRNA pseudouridine synthase A 2 - Bacillus
           anthracis
          Length = 245

 Score = 37.1 bits (82), Expect = 0.36
 Identities = 22/66 (33%), Positives = 38/66 (57%), Gaps = 4/66 (6%)
 Frame = +2

Query: 449 SRTDKGVSAAEQVVSLKLP---LEVNVEE-INKRLPETIKVFAVKRVTNRFNSKSKCNAR 616
           SRTD GV A  QV + +     +E  V++ +N+ LP  I +  V+ V +RF+++    A+
Sbjct: 50  SRTDAGVHALNQVANFQSDEKLVEHKVKKYLNQYLPNDISITNVEEVHDRFHARYNSKAK 109

Query: 617 SYSYTL 634
           +Y Y +
Sbjct: 110 TYLYKI 115


>UniRef50_Q21IY8 Cluster: Pseudouridylate synthase; n=2;
           Gammaproteobacteria|Rep: Pseudouridylate synthase -
           Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM
           17024)
          Length = 289

 Score = 36.7 bits (81), Expect = 0.48
 Identities = 20/67 (29%), Positives = 35/67 (52%), Gaps = 4/67 (5%)
 Frame = +2

Query: 446 SSRTDKGVSAAEQVVSLKL----PLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNA 613
           + RTD GV A  Q+V        P +  ++ +N  LP +I+V + K V   F+++    +
Sbjct: 70  AGRTDAGVHATSQIVHFDTLAGRPSKAWLQGVNTHLPFSIRVISAKEVGFDFHARFSALS 129

Query: 614 RSYSYTL 634
           R+Y Y +
Sbjct: 130 RTYRYVI 136


>UniRef50_Q6G7A2 Cluster: tRNA pseudouridine synthase A; n=16;
           Staphylococcus|Rep: tRNA pseudouridine synthase A -
           Staphylococcus aureus (strain MSSA476)
          Length = 267

 Score = 36.7 bits (81), Expect = 0.48
 Identities = 22/72 (30%), Positives = 36/72 (50%), Gaps = 4/72 (5%)
 Frame = +2

Query: 425 QNAQFQRSSRTDKGVSAAEQV----VSLKLPLEVNVEEINKRLPETIKVFAVKRVTNRFN 592
           ++ +   SSRTD+GV A +Q       L +P+      +N+ LP+ I V  V  V + F+
Sbjct: 40  RHVRIHPSSRTDRGVHAIQQYFHFDTELNIPMSQWQYAMNRTLPDDIYVNNVVTVDDDFH 99

Query: 593 SKSKCNARSYSY 628
            +  C  + Y Y
Sbjct: 100 CRYDCVGKRYRY 111


>UniRef50_A0ZG49 Cluster: Pseudouridylate synthase; n=3;
           Cyanobacteria|Rep: Pseudouridylate synthase - Nodularia
           spumigena CCY 9414
          Length = 296

 Score = 36.3 bits (80), Expect = 0.63
 Identities = 23/69 (33%), Positives = 34/69 (49%), Gaps = 4/69 (5%)
 Frame = +2

Query: 446 SSRTDKGVSAAEQVVSLK----LPLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNA 613
           + RTD GV AA QV   +    +P       +N  LP+ I + A   V NR++++     
Sbjct: 58  AGRTDSGVHAAAQVAHFEATGLIPPHRWASILNSYLPQDILIKASAAVDNRWHARFSAAY 117

Query: 614 RSYSYTLPT 640
           R Y YT+ T
Sbjct: 118 RRYRYTIYT 126


>UniRef50_Q9C5K6 Cluster: Pseudouridylate synthase; n=3; core
           eudicotyledons|Rep: Pseudouridylate synthase -
           Arabidopsis thaliana (Mouse-ear cress)
          Length = 446

 Score = 36.3 bits (80), Expect = 0.63
 Identities = 45/201 (22%), Positives = 81/201 (40%), Gaps = 22/201 (10%)
 Frame = +2

Query: 92  LAITSARLLSVMEAADVTKDEENKSIDIVPNKLLTRYNKRRAHRDWETKPPGEIKKPYER 271
           L + +A+LLS + +    + E      +  +  L R  +RR  +  +   P  +      
Sbjct: 35  LEVENAKLLSQVSSCQCQQMEVKHDRSLSDSSSLVR--RRRVRKGDKNSIPSHL------ 86

Query: 272 IKRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSS 451
           I ++ +A+ + Y G  +YG      ++               +   D    +++ + R  
Sbjct: 87  ISKRYVALKIMYFGKRFYGFSAEAQMEPSIESEVFKALERTRLLVGD---KKDSCYSRCG 143

Query: 452 RTDKGVSAAEQVVS------LKLP-----LEVN-----------VEEINKRLPETIKVFA 565
           RTDKGVS+  QV++      LK P      +VN           V  +N+ LP+ I+V  
Sbjct: 144 RTDKGVSSTGQVIALFLRSRLKSPPGDSKAQVNGRTGERPEYDYVRVLNRALPDDIRVIG 203

Query: 566 VKRVTNRFNSKSKCNARSYSY 628
                  F+++  C AR Y Y
Sbjct: 204 WSPAPIDFHARFSCYAREYKY 224


>UniRef50_Q011R7 Cluster: Exopolyphosphatases and related proteins;
           n=3; Ostreococcus|Rep: Exopolyphosphatases and related
           proteins - Ostreococcus tauri
          Length = 813

 Score = 36.3 bits (80), Expect = 0.63
 Identities = 23/77 (29%), Positives = 36/77 (46%), Gaps = 9/77 (11%)
 Frame = +2

Query: 425 QNAQFQRSSRTDKGVSAAEQVVSLKL-------PLEV--NVEEINKRLPETIKVFAVKRV 577
           + A + R  RTD+GVS   Q+V+L++       P E    V  +N+ LP  ++      V
Sbjct: 504 KTASYARCGRTDRGVSGLGQIVTLQVRSNGASDPREELDYVGLLNRALPSDVRALGWAPV 563

Query: 578 TNRFNSKSKCNARSYSY 628
               N++  C  R Y Y
Sbjct: 564 DEELNARFDCKWRQYKY 580


>UniRef50_Q7TU31 Cluster: tRNA pseudouridine synthase A; n=5;
           Prochlorococcus marinus|Rep: tRNA pseudouridine synthase
           A - Prochlorococcus marinus subsp. pastoris (strain CCMP
           1378 / MED4)
          Length = 268

 Score = 36.3 bits (80), Expect = 0.63
 Identities = 20/67 (29%), Positives = 34/67 (50%), Gaps = 4/67 (5%)
 Frame = +2

Query: 446 SSRTDKGVSAAEQVVSLKL----PLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNA 613
           S RTD GV A+ QV+   +    P++   + +N RLP TI++     V + +++      
Sbjct: 48  SGRTDAGVHASGQVIHFDIDFLIPIDRYADVLNSRLPHTIRILESVEVKSSWHACYSAVY 107

Query: 614 RSYSYTL 634
           R Y Y +
Sbjct: 108 RHYRYVI 114


>UniRef50_A6NVS7 Cluster: Pseudouridylate synthase; n=1; Bacteroides
           capillosus ATCC 29799|Rep: Pseudouridylate synthase -
           Bacteroides capillosus ATCC 29799
          Length = 249

 Score = 35.9 bits (79), Expect = 0.83
 Identities = 20/67 (29%), Positives = 32/67 (47%), Gaps = 4/67 (5%)
 Frame = +2

Query: 446 SSRTDKGVSAAEQVVSLK----LPLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNA 613
           + RTD GV A   + + +    +P +     +N RLPE I V     V + FN+   C  
Sbjct: 48  AGRTDAGVHAENYIANFRTTSTIPCDRLPLAVNTRLPEDIVVVKATEVHDGFNAIGSCIK 107

Query: 614 RSYSYTL 634
           + Y+Y +
Sbjct: 108 KEYTYRI 114


>UniRef50_Q0UN59 Cluster: Putative uncharacterized protein; n=1;
           Phaeosphaeria nodorum|Rep: Putative uncharacterized
           protein - Phaeosphaeria nodorum (Septoria nodorum)
          Length = 498

 Score = 35.9 bits (79), Expect = 0.83
 Identities = 20/52 (38%), Positives = 28/52 (53%), Gaps = 5/52 (9%)
 Frame = +1

Query: 247 RNQKTIRKD*EKKNGYAAGVLRS*IL---RYA--TKSWCTNNRRRIIKSIVG 387
           R+  T R + EK+NGY    + S +L    YA   KSWC  N  +I+ S+ G
Sbjct: 168 RSADTRRDEAEKRNGYITRPMNSFMLYRSAYAERAKSWCAQNNHQIVSSVAG 219


>UniRef50_Q72I65 Cluster: tRNA pseudouridine synthase A; n=3;
           Thermus thermophilus|Rep: tRNA pseudouridine synthase A
           - Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM
           7039)
          Length = 253

 Score = 35.9 bits (79), Expect = 0.83
 Identities = 21/67 (31%), Positives = 33/67 (49%), Gaps = 4/67 (5%)
 Frame = +2

Query: 446 SSRTDKGVSAAEQV----VSLKLPLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNA 613
           + RTD GV A        V   +P+E   E +N+ LPE +KV   + V   F+++     
Sbjct: 48  AGRTDAGVHALAMPFHVDVESAIPVEKVPEALNRLLPEDLKVVGAREVAPDFHARKDALW 107

Query: 614 RSYSYTL 634
           R+Y Y +
Sbjct: 108 RAYRYRI 114


>UniRef50_Q47HQ7 Cluster: Pseudouridylate synthase; n=1;
           Dechloromonas aromatica RCB|Rep: Pseudouridylate
           synthase - Dechloromonas aromatica (strain RCB)
          Length = 262

 Score = 35.5 bits (78), Expect = 1.1
 Identities = 21/67 (31%), Positives = 30/67 (44%), Gaps = 4/67 (5%)
 Frame = +2

Query: 446 SSRTDKGVSAAEQVVSLKLPLE----VNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNA 613
           + RTD GV A  QV     P++      V  +N  LPE + V   + V   F+++     
Sbjct: 47  AGRTDAGVHATHQVAHFDAPVDRPLTAWVRGVNSHLPEGVAVRWAQPVAEDFHARFSARG 106

Query: 614 RSYSYTL 634
           R Y Y L
Sbjct: 107 RRYRYLL 113


>UniRef50_A6BIC3 Cluster: Pseudouridylate synthase; n=1; Dorea
           longicatena DSM 13814|Rep: Pseudouridylate synthase -
           Dorea longicatena DSM 13814
          Length = 245

 Score = 35.5 bits (78), Expect = 1.1
 Identities = 19/65 (29%), Positives = 32/65 (49%), Gaps = 4/65 (6%)
 Frame = +2

Query: 452 RTDKGVSAAEQVVSLKLPLEVNVEEI----NKRLPETIKVFAVKRVTNRFNSKSKCNARS 619
           RT+ GV A  Q+ + K       + I    N+ LP  I +  VK V  RF+++    +++
Sbjct: 54  RTEVGVHAYAQIANFKTSSSTTTQNIKHYLNRYLPMDIAIIDVKEVPERFHAQLNATSKT 113

Query: 620 YSYTL 634
           Y Y +
Sbjct: 114 YVYRM 118


>UniRef50_Q4SEJ2 Cluster: Pseudouridylate synthase; n=3;
           Tetraodontidae|Rep: Pseudouridylate synthase - Tetraodon
           nigroviridis (Green puffer)
          Length = 412

 Score = 35.1 bits (77), Expect = 1.5
 Identities = 35/147 (23%), Positives = 58/147 (39%), Gaps = 27/147 (18%)
 Frame = +2

Query: 278 RKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRT 457
           R+ +A+ L Y G  Y G                       + Q+     Q++ + R  RT
Sbjct: 72  RRHVALRLAYLGWAYQGFAVQENTDNTVEARLFEALHKTCLIQD----RQSSNYHRCGRT 127

Query: 458 DKGVSAAEQVVSL-------------KLPLEVN--------------VEEINKRLPETIK 556
           DKGVSA  QV+++             KLP  V+              V+ +N+ LP  I+
Sbjct: 128 DKGVSAFSQVITIESRSTQFCGGLGVKLPENVDADKKSQTAVSELPYVKMLNRVLPHDIR 187

Query: 557 VFAVKRVTNRFNSKSKCNARSYSYTLP 637
           ++        F+++  C +R+Y Y  P
Sbjct: 188 IWNWAPAAEGFSARFDCQSRTYRYYFP 214


>UniRef50_Q1Q1P7 Cluster: Pseudouridylate synthase; n=1; Candidatus
           Kuenenia stuttgartiensis|Rep: Pseudouridylate synthase -
           Candidatus Kuenenia stuttgartiensis
          Length = 244

 Score = 35.1 bits (77), Expect = 1.5
 Identities = 20/74 (27%), Positives = 36/74 (48%), Gaps = 4/74 (5%)
 Frame = +2

Query: 425 QNAQFQRSSRTDKGVSAAEQVVSLK----LPLEVNVEEINKRLPETIKVFAVKRVTNRFN 592
           +  +   + RTD GV A  QV + K    +P +  +  IN  LP+ I +  V  +   F+
Sbjct: 41  EEVEIHGAGRTDAGVHALGQVANFKTYSAIPAKQLLRAINFHLPQDITIKDVADMEEGFH 100

Query: 593 SKSKCNARSYSYTL 634
           ++    ++ Y YT+
Sbjct: 101 ARYSATSKVYRYTV 114


>UniRef50_A7HKV8 Cluster: tRNA pseudouridine synthase A; n=1;
           Fervidobacterium nodosum Rt17-B1|Rep: tRNA pseudouridine
           synthase A - Fervidobacterium nodosum Rt17-B1
          Length = 246

 Score = 35.1 bits (77), Expect = 1.5
 Identities = 32/125 (25%), Positives = 52/125 (41%), Gaps = 5/125 (4%)
 Frame = +2

Query: 281 KKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTD 460
           +++A+   Y G +++G Q    V+T+             I  + +          + RTD
Sbjct: 2   RRVAIEFSYDGTDFFGYQIQNNVRTVQGELEKALEKVFKIHIDTYA---------AGRTD 52

Query: 461 KGVSAAEQVVSLKLP----LEVNVEE-INKRLPETIKVFAVKRVTNRFNSKSKCNARSYS 625
            GV A  QVVS   P    +E +++  IN  LP  I +  V      FN + +   R Y 
Sbjct: 53  TGVHANGQVVSFDCPNDRLMENDIKNAINANLPGDIYIKKVWFTHPTFNPRYEAKRRIYH 112

Query: 626 YTLPT 640
           Y + T
Sbjct: 113 YYIDT 117


>UniRef50_A7SJV8 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 464

 Score = 35.1 bits (77), Expect = 1.5
 Identities = 38/164 (23%), Positives = 67/164 (40%), Gaps = 27/164 (16%)
 Frame = +2

Query: 230 ETKPPGEIKKPYERIKRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQE 409
           ++KP  E    + R   +++A+ L Y G + +G      +                + + 
Sbjct: 65  KSKPRKEFD--FSRYNTRRIALRLSYLGWDMHGFASQEKIDNTVEAHLFDALIKACLVK- 121

Query: 410 DFENAQNAQFQRSSRTDKGVSAAEQVVSLKLPLEVN---------------------VEE 526
              + ++  + R  RTDKGVSA  QV+SL +   ++                     ++E
Sbjct: 122 ---SRESCSYSRCGRTDKGVSAFGQVISLNVRTNLDKGPGVILRQESSVGRDTKGKTMKE 178

Query: 527 I------NKRLPETIKVFAVKRVTNRFNSKSKCNARSYSYTLPT 640
           I      NK LP+ I+V A   V   F+++  C+ R Y Y  P+
Sbjct: 179 ILYVDILNKVLPKEIRVLAWAPVELDFDARFSCSYRKYKYLFPS 222


>UniRef50_A7ANH8 Cluster: tRNA pseudouridine synthase A family
           protein; n=1; Babesia bovis|Rep: tRNA pseudouridine
           synthase A family protein - Babesia bovis
          Length = 248

 Score = 35.1 bits (77), Expect = 1.5
 Identities = 20/54 (37%), Positives = 27/54 (50%)
 Frame = +2

Query: 467 VSAAEQVVSLKLPLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYSY 628
           VS  E+ V     +    + INK LP  I+V  VK V + F+S+  C  R Y Y
Sbjct: 92  VSPDERGVGPCYRINTFTKAINKHLPRGIRVNWVKHVPDDFSSRRNCTFRVYKY 145


>UniRef50_Q9KTA4 Cluster: tRNA pseudouridine synthase A; n=29;
           Gammaproteobacteria|Rep: tRNA pseudouridine synthase A -
           Vibrio cholerae
          Length = 264

 Score = 35.1 bits (77), Expect = 1.5
 Identities = 32/121 (26%), Positives = 47/121 (38%), Gaps = 4/121 (3%)
 Frame = +2

Query: 284 KMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTDK 463
           ++A+ + Y G  YYG QR   V+++             I     E       Q + RTD 
Sbjct: 2   RIALGIEYDGTHYYGWQRQREVKSVQEALEKALSK---IANHPVE------VQCAGRTDA 52

Query: 464 GVSAAEQVVSLKLPLEVNVEE----INKRLPETIKVFAVKRVTNRFNSKSKCNARSYSYT 631
           GV    QVV      E  +       N  LP+ I V     V + F+++    AR Y Y 
Sbjct: 53  GVHGTGQVVHFDTTAERQMVAWTMGANANLPKDIAVRWAMAVPDEFHARFSATARRYRYV 112

Query: 632 L 634
           +
Sbjct: 113 I 113


>UniRef50_Q6I4Q2 Cluster: tRNA pseudouridine synthase A 1; n=14;
           Bacillaceae|Rep: tRNA pseudouridine synthase A 1 -
           Bacillus anthracis
          Length = 247

 Score = 35.1 bits (77), Expect = 1.5
 Identities = 26/114 (22%), Positives = 46/114 (40%), Gaps = 4/114 (3%)
 Frame = +2

Query: 299 LGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTDKGVSAA 478
           + Y G+ + G Q  P  +T+                +     +  + Q S RTD  V A 
Sbjct: 8   VAYDGMHFCGYQIQPQHRTVQQEIEKAL--------QKLHKGELVRVQASGRTDSTVHAK 59

Query: 479 EQVVSLKLPLEVNVEE----INKRLPETIKVFAVKRVTNRFNSKSKCNARSYSY 628
            QV+    PL +   +    +N  LP+ I +  V++ T  F+++     + Y Y
Sbjct: 60  GQVIHFDTPLSLEEWQWSNALNTMLPDDIVITQVEKKTEEFHARYGVERKEYRY 113


>UniRef50_Q0AUL4 Cluster: Pseudouridylate synthase; n=1;
           Syntrophomonas wolfei subsp. wolfei str. Goettingen|Rep:
           Pseudouridylate synthase - Syntrophomonas wolfei subsp.
           wolfei (strain Goettingen)
          Length = 249

 Score = 34.7 bits (76), Expect = 1.9
 Identities = 29/121 (23%), Positives = 47/121 (38%), Gaps = 4/121 (3%)
 Frame = +2

Query: 284 KMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTDK 463
           ++ +LL Y G  Y+G Q      T+                    + + A    + RTD 
Sbjct: 3   RIKLLLEYDGSNYHGFQLQKNANTVQAELEKAIYRL---------SGERATIVCAGRTDA 53

Query: 464 GVSAAEQVVSLK----LPLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYSYT 631
           GV A  QVV+      +P +     +N +LPE I+V   +     FN +     + Y Y 
Sbjct: 54  GVHAWGQVVAFDSCSTIPGDRWAYALNSQLPEDIQVLESQETRAEFNPRFDALKKCYGYL 113

Query: 632 L 634
           +
Sbjct: 114 I 114


>UniRef50_A5I338 Cluster: Pseudouridylate synthase; n=7;
           Clostridiaceae|Rep: Pseudouridylate synthase -
           Clostridium botulinum A str. ATCC 3502
          Length = 246

 Score = 34.7 bits (76), Expect = 1.9
 Identities = 21/67 (31%), Positives = 33/67 (49%), Gaps = 4/67 (5%)
 Frame = +2

Query: 446 SSRTDKGVSAAEQVVSLKLPLEVNVEEI----NKRLPETIKVFAVKRVTNRFNSKSKCNA 613
           S RTD GV A  QV +     + + +EI     + LP+ I V+    V  RF+S+     
Sbjct: 49  SGRTDTGVHANMQVANFHTTFQGSTDEILSYCYEYLPKDIVVYDAFHVDERFHSRLNVKK 108

Query: 614 RSYSYTL 634
           + Y+Y +
Sbjct: 109 KKYTYKI 115


>UniRef50_P60351 Cluster: tRNA pseudouridine synthase A; n=2;
           Candidatus Phytoplasma asteris|Rep: tRNA pseudouridine
           synthase A - Onion yellows phytoplasma
          Length = 243

 Score = 34.7 bits (76), Expect = 1.9
 Identities = 28/116 (24%), Positives = 47/116 (40%), Gaps = 4/116 (3%)
 Frame = +2

Query: 293 MLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTDKGVS 472
           ++L Y G  YYG Q+ P   T+            +         QN     +SRTDKGV 
Sbjct: 8   LILSYDGTCYYGYQKQPQKITVQQTFEKALKKMTH---------QNIPTFAASRTDKGVH 58

Query: 473 AAEQVVSLKLPLEVN----VEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYSY 628
           +  Q +  +    +      + +N  LP  I+V  +   T  F+++    ++ Y Y
Sbjct: 59  SQGQTLHFQTTFFLKPTHFQKTLNYLLPPDIRVRQMNFATPNFHARYSAKSKIYQY 114


>UniRef50_UPI000023D4AE Cluster: hypothetical protein FG10837.1;
           n=1; Gibberella zeae PH-1|Rep: hypothetical protein
           FG10837.1 - Gibberella zeae PH-1
          Length = 538

 Score = 34.3 bits (75), Expect = 2.5
 Identities = 30/116 (25%), Positives = 47/116 (40%), Gaps = 4/116 (3%)
 Frame = +2

Query: 233 TKPPGEIKKPYERIKRKKMAMLLGYSGVEYYGM--QRNPGVQTIXXXXXXXXXXXXYITQ 406
           TKP  + K    +   + +A+ L Y G  Y G   Q      +I             I  
Sbjct: 45  TKPKVKRKMDPNKYTTRYIALKLAYLGKNYGGFEFQAMANAPSIEEELWNALTKACLIFP 104

Query: 407 ED--FENAQNAQFQRSSRTDKGVSAAEQVVSLKLPLEVNVEEINKRLPETIKVFAV 568
           ED    +    ++ +  RTDKGVSA  QV+ L++     V +  +R+ E  +   V
Sbjct: 105 EDERIVDFDCCEYSKCGRTDKGVSAFGQVIGLRVRSARPVPKKRRRMSEAGEAMVV 160


>UniRef50_Q30RV9 Cluster: Pseudouridylate synthase; n=1;
           Thiomicrospira denitrificans ATCC 33889|Rep:
           Pseudouridylate synthase - Thiomicrospira denitrificans
           (strain ATCC 33889 / DSM 1351)
          Length = 236

 Score = 34.3 bits (75), Expect = 2.5
 Identities = 20/68 (29%), Positives = 35/68 (51%), Gaps = 5/68 (7%)
 Frame = +2

Query: 446 SSRTDKGVSAAEQVVSLKLP-----LEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCN 610
           S RTD+GV A+ QV  + LP     +    + + + LP +I +  +K V + F+++    
Sbjct: 47  SGRTDRGVHASGQVCHIDLPPYWSDITKLQDSLGRVLPPSILIKKIKIVDDTFHARYSAK 106

Query: 611 ARSYSYTL 634
            R Y Y +
Sbjct: 107 RRVYRYII 114


>UniRef50_Q8GB97 Cluster: Pseudouridylate synthase; n=2;
           Clostridiales|Rep: Pseudouridylate synthase -
           Heliobacillus mobilis
          Length = 249

 Score = 34.3 bits (75), Expect = 2.5
 Identities = 28/116 (24%), Positives = 45/116 (38%), Gaps = 4/116 (3%)
 Frame = +2

Query: 299 LGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTDKGVSAA 478
           + Y G  Y+G Q       +             +T E+       +   + RTD GV A 
Sbjct: 1   MSYDGTSYHGFQTQEDPTNLPTIQDELMRAIQVLTGEE------VKITCAGRTDAGVHAR 54

Query: 479 EQVVSL----KLPLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYSYTL 634
            QVV      ++P E     +N  LP+ I V   + V   F+S+     + Y Y++
Sbjct: 55  GQVVDFLTTSRIPDEKFPLAMNSLLPKDIAVVKAETVAEDFHSRFGALGKHYRYSI 110


>UniRef50_Q1FLK6 Cluster: Pseudouridylate synthase; n=1; Clostridium
           phytofermentans ISDg|Rep: Pseudouridylate synthase -
           Clostridium phytofermentans ISDg
          Length = 276

 Score = 34.3 bits (75), Expect = 2.5
 Identities = 30/122 (24%), Positives = 48/122 (39%), Gaps = 4/122 (3%)
 Frame = +2

Query: 281 KKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTD 460
           + + +++ Y G  Y G Q+  G Q                     EN +      ++RT+
Sbjct: 30  RNIQLIIEYDGSRYDGWQKQAGNQKSITIQDKLEDVL-----NKMEN-ETVTVIGAARTE 83

Query: 461 KGVSAAEQVVSLKLPLEVNVEEI----NKRLPETIKVFAVKRVTNRFNSKSKCNARSYSY 628
            GV A +QV S     ++ V EI    N+ LP  I V     V  RF++     +  Y Y
Sbjct: 84  AGVHAYKQVASFMTNSKLKVYEIKQYLNRFLPRDIAVLEALEVPERFHASFNAGSFEYEY 143

Query: 629 TL 634
            +
Sbjct: 144 KI 145


>UniRef50_A7I1Z3 Cluster: tRNA pseudouridine synthase A; n=1;
           Campylobacter hominis ATCC BAA-381|Rep: tRNA
           pseudouridine synthase A - Campylobacter hominis (strain
           ATCC BAA-381 / LMG 19568 / NCTC 13146 /CH001A)
          Length = 278

 Score = 34.3 bits (75), Expect = 2.5
 Identities = 23/73 (31%), Positives = 34/73 (46%), Gaps = 4/73 (5%)
 Frame = +2

Query: 428 NAQFQRSSRTDKGVSAAEQVVSLKLPLEVNVEE----INKRLPETIKVFAVKRVTNRFNS 595
           N +   +SRTDKGV A  QV +       +++     IN+    +I V  ++R    F  
Sbjct: 44  NEKVISASRTDKGVHALSQVSTTHCAAFWDLQNLRHFINRHAKPSIYVRKIERADENFQV 103

Query: 596 KSKCNARSYSYTL 634
           +    ARSY Y L
Sbjct: 104 RFDAKARSYRYIL 116


>UniRef50_A0RNY9 Cluster: Pseudouridylate synthase; n=2;
           Campylobacter|Rep: Pseudouridylate synthase -
           Campylobacter fetus subsp. fetus (strain 82-40)
          Length = 258

 Score = 34.3 bits (75), Expect = 2.5
 Identities = 23/69 (33%), Positives = 35/69 (50%), Gaps = 6/69 (8%)
 Frame = +2

Query: 446 SSRTDKGVSAAEQVVSLKLP------LEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKC 607
           SSRTDKGV A  QV  ++         E    +INK     I +  +++V++ F+ +   
Sbjct: 47  SSRTDKGVHAISQVSCVECGEFWNERFERLKNQINKHTKPYIYIKNIQKVSDEFHPRYDA 106

Query: 608 NARSYSYTL 634
            ARSY Y +
Sbjct: 107 VARSYRYII 115


>UniRef50_A5E5W9 Cluster: Putative uncharacterized protein; n=1;
           Lodderomyces elongisporus NRRL YB-4239|Rep: Putative
           uncharacterized protein - Lodderomyces elongisporus
           (Yeast) (Saccharomyces elongisporus)
          Length = 380

 Score = 34.3 bits (75), Expect = 2.5
 Identities = 18/70 (25%), Positives = 36/70 (51%), Gaps = 1/70 (1%)
 Frame = +2

Query: 398 ITQEDFENAQNAQFQRSSRTDKGVSAAEQVVSLKLPLEVNVEEINKRLPETIK-VFAVKR 574
           ++QE+FENA+      + + D  V  +   V  K   E   EE+ K+L   ++ ++  + 
Sbjct: 240 LSQEEFENAKQNYMNLAKKVDDAVCVSVDGVLYKSRTEEENEELKKKLLSQLETLYETEA 299

Query: 575 VTNRFNSKSK 604
            +N + SK++
Sbjct: 300 ASNEYRSKAQ 309


>UniRef50_Q6MEE7 Cluster: tRNA pseudouridine synthase A 1; n=1;
           Candidatus Protochlamydia amoebophila UWE25|Rep: tRNA
           pseudouridine synthase A 1 - Protochlamydia amoebophila
           (strain UWE25)
          Length = 256

 Score = 34.3 bits (75), Expect = 2.5
 Identities = 22/67 (32%), Positives = 33/67 (49%), Gaps = 4/67 (5%)
 Frame = +2

Query: 446 SSRTDKGVSAAEQVVSLKLPLEVNVEEI----NKRLPETIKVFAVKRVTNRFNSKSKCNA 613
           S RTD GV A  QV        +++  +    N  LP  I++ AV+ V+ RF+S+     
Sbjct: 49  SGRTDAGVHAKGQVAHFHFQDYIDLSRLHVSLNGLLPRDIRIKAVEPVSPRFHSQYSAIR 108

Query: 614 RSYSYTL 634
           + Y Y L
Sbjct: 109 KEYHYYL 115


>UniRef50_UPI0000E48924 Cluster: PREDICTED: similar to FKSG32,
           partial; n=1; Strongylocentrotus purpuratus|Rep:
           PREDICTED: similar to FKSG32, partial -
           Strongylocentrotus purpuratus
          Length = 224

 Score = 33.9 bits (74), Expect = 3.4
 Identities = 23/87 (26%), Positives = 41/87 (47%), Gaps = 2/87 (2%)
 Frame = +2

Query: 248 EIKKPYE--RIKRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFEN 421
           +I +P++  +   + +A+ + Y G +Y+G      VQ                  +  E+
Sbjct: 50  KIPRPFDFKKYNTRHVALKITYLGWDYHGFV----VQEDSNNTVEHHLFEALTKTKLIES 105

Query: 422 AQNAQFQRSSRTDKGVSAAEQVVSLKL 502
            Q + + R  RTDKGVSA  QV+++ L
Sbjct: 106 RQTSNYSRCGRTDKGVSAFGQVIAIDL 132


>UniRef50_Q4ALX6 Cluster: Pseudouridylate synthase; n=1; Chlorobium
           phaeobacteroides BS1|Rep: Pseudouridylate synthase -
           Chlorobium phaeobacteroides BS1
          Length = 233

 Score = 33.9 bits (74), Expect = 3.4
 Identities = 29/117 (24%), Positives = 51/117 (43%), Gaps = 5/117 (4%)
 Frame = +2

Query: 293 MLLGYSGVEYYGMQRNP-GVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTDKGV 469
           M + Y G ++ G Q+ P GV T+             I QE+           + RTD+GV
Sbjct: 1   MTIEYDGTDFSGWQKQPEGVVTVQGVLETTLSR---IVQEE------VVMTAAGRTDRGV 51

Query: 470 SAAEQVVSLKLPLEVN----VEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYSY 628
            A  QV + +    ++    +  +N  LP T+ +  ++ V + F+++     R Y Y
Sbjct: 52  HARGQVANFRTASCLSTGRLLHSLNALLPSTVCIRDMQEVPDSFHARYSALFREYRY 108


>UniRef50_Q5CV63 Cluster: Pseudouridylate synthase; n=2;
           Cryptosporidium|Rep: Pseudouridylate synthase -
           Cryptosporidium parvum Iowa II
          Length = 283

 Score = 33.9 bits (74), Expect = 3.4
 Identities = 22/72 (30%), Positives = 32/72 (44%), Gaps = 7/72 (9%)
 Frame = +2

Query: 443 RSSRTDKGVSAAEQVVSLKLPLEVN-------VEEINKRLPETIKVFAVKRVTNRFNSKS 601
           R  RTD+GV +A   +S+ L            +E +N  LP  I+V     V   F+++ 
Sbjct: 42  RCGRTDRGVHSAGNYISVNLRTRAKNLEPYNYMEMLNGVLPWDIRVIGYCEVRPDFSARF 101

Query: 602 KCNARSYSYTLP 637
            C  R Y Y  P
Sbjct: 102 DCEYRLYKYFFP 113


>UniRef50_A0CKA3 Cluster: Chromosome undetermined scaffold_2, whole
           genome shotgun sequence; n=4; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_2,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 429

 Score = 33.9 bits (74), Expect = 3.4
 Identities = 24/95 (25%), Positives = 46/95 (48%)
 Frame = +2

Query: 263 YERIKRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQ 442
           ++++KR K+   L +  +  Y  ++ PG+Q I              TQE+ +N +N Q +
Sbjct: 290 FQKLKRSKLQESLKHK-IHMYNPKQIPGIQKIIESIQTANNTIAKTTQENVQNEENKQ-E 347

Query: 443 RSSRTDKGVSAAEQVVSLKLPLEVNVEEINKRLPE 547
           +S + D  V    Q V+ +     +V E+N+ + E
Sbjct: 348 QSDQGDNAV-IENQNVNQQEDNNNDVNEVNEAVNE 381


>UniRef50_Q30XU3 Cluster: Pseudouridylate synthase; n=2;
           Desulfovibrionaceae|Rep: Pseudouridylate synthase -
           Desulfovibrio desulfuricans (strain G20)
          Length = 278

 Score = 33.5 bits (73), Expect = 4.4
 Identities = 21/67 (31%), Positives = 34/67 (50%), Gaps = 4/67 (5%)
 Frame = +2

Query: 446 SSRTDKGVSAAEQVVSLKLP-LEVNVE---EINKRLPETIKVFAVKRVTNRFNSKSKCNA 613
           + RTD GV A  QV  L +P  +  V+    +N +LPE I V     V + F+++     
Sbjct: 57  AGRTDSGVHAEGQVAHLDIPDAKAAVDWRRALNAKLPEDISVLQAAVVPDGFHARFDAVK 116

Query: 614 RSYSYTL 634
           + Y+Y +
Sbjct: 117 KRYTYRI 123


>UniRef50_A3ZQX0 Cluster: Pseudouridylate synthase; n=2;
           Bacteria|Rep: Pseudouridylate synthase - Blastopirellula
           marina DSM 3645
          Length = 260

 Score = 33.5 bits (73), Expect = 4.4
 Identities = 21/67 (31%), Positives = 32/67 (47%), Gaps = 4/67 (5%)
 Frame = +2

Query: 446 SSRTDKGVSAAEQVVSLKLPLEVNVE----EINKRLPETIKVFAVKRVTNRFNSKSKCNA 613
           S RTD GV A  QVVS ++  +++ +     +N  LP  I V + +     FN+      
Sbjct: 53  SGRTDSGVHAIGQVVSFRMQSQLSPDVMRRALNAELPPDIVVQSARNAIPEFNAIDCAIK 112

Query: 614 RSYSYTL 634
           + Y Y L
Sbjct: 113 KRYRYLL 119


>UniRef50_Q8ZXR6 Cluster: tRNA pseudouridine synthase A; n=4;
           Pyrobaculum|Rep: tRNA pseudouridine synthase A -
           Pyrobaculum aerophilum
          Length = 256

 Score = 33.5 bits (73), Expect = 4.4
 Identities = 20/65 (30%), Positives = 30/65 (46%)
 Frame = +2

Query: 443 RSSRTDKGVSAAEQVVSLKLPLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSY 622
           R SRTD GVSA   VV     + +    +N ++P+    + +  V   FN + +   R Y
Sbjct: 38  RGSRTDPGVSAVGNVVMTGRKMALGY--VNSKMPKGAWAWGIAEVPEGFNPR-RAKLRRY 94

Query: 623 SYTLP 637
            Y  P
Sbjct: 95  LYVAP 99


>UniRef50_Q26G59 Cluster: Pseudouridylate synthase; n=5;
           Flavobacteria|Rep: Pseudouridylate synthase -
           Flavobacteria bacterium BBFL7
          Length = 267

 Score = 33.1 bits (72), Expect = 5.9
 Identities = 28/115 (24%), Positives = 44/115 (38%), Gaps = 5/115 (4%)
 Frame = +2

Query: 299 LGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTDKGVSAA 478
           L Y G  ++G Q+ P V T+              T     +  N +   + RTD  VS  
Sbjct: 15  LQYLGFRFHGWQKQPDVPTVEKMVKR--------TLRFVLDHHNFKVLAAGRTDARVSVN 66

Query: 479 EQVVSL-----KLPLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYSY 628
           E ++ L      L L+  + E N  LP  I+   ++    +FN       + Y Y
Sbjct: 67  ETIIELFLDDEALNLDTFLAEFNLNLPSDIRALDIEETNAQFNVIQHPKEKEYIY 121


>UniRef50_Q1NSM9 Cluster: Putative uncharacterized protein; n=1;
           delta proteobacterium MLMS-1|Rep: Putative
           uncharacterized protein - delta proteobacterium MLMS-1
          Length = 90

 Score = 33.1 bits (72), Expect = 5.9
 Identities = 20/70 (28%), Positives = 33/70 (47%)
 Frame = +2

Query: 110 RLLSVMEAADVTKDEENKSIDIVPNKLLTRYNKRRAHRDWETKPPGEIKKPYERIKRKKM 289
           R L+++   D    E+      V  +   RY   R   +W+T   GE K+ + RI R  +
Sbjct: 17  RSLALVNTYDARGAEKPAMGFTVAKRKGIRYVGGRGVTEWKTMAGGEKKRGHGRISRNPL 76

Query: 290 AMLLGYSGVE 319
            +L+G  G+E
Sbjct: 77  ILLVGRIGIE 86


>UniRef50_Q7QX52 Cluster: Pseudouridylate synthase; n=1; Giardia
           lamblia ATCC 50803|Rep: Pseudouridylate synthase -
           Giardia lamblia ATCC 50803
          Length = 351

 Score = 33.1 bits (72), Expect = 5.9
 Identities = 19/74 (25%), Positives = 37/74 (50%), Gaps = 1/74 (1%)
 Frame = +2

Query: 284 KMAMLLGYSGVEYYGMQRNP-GVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTD 460
           ++A+L+ + G  ++G    P G  T+            Y+ +   E  ++ + +R+ RTD
Sbjct: 2   RVALLVAFHGTAFHGNAYQPTGGSTVEGALFEGLQKTGYLKEN--ETIKDIELERTGRTD 59

Query: 461 KGVSAAEQVVSLKL 502
            GVSA   + +L+L
Sbjct: 60  AGVSAECMLYTLQL 73


>UniRef50_Q4N208 Cluster: Putative uncharacterized protein; n=1;
           Theileria parva|Rep: Putative uncharacterized protein -
           Theileria parva
          Length = 408

 Score = 33.1 bits (72), Expect = 5.9
 Identities = 20/81 (24%), Positives = 40/81 (49%)
 Frame = +2

Query: 395 YITQEDFENAQNAQFQRSSRTDKGVSAAEQVVSLKLPLEVNVEEINKRLPETIKVFAVKR 574
           Y    +  N      Q  S T + ++  + V +L +P  + V+ ++   P T++  +V +
Sbjct: 180 YTRPTNLFNTNLTTIQSQSETPEYLNRVDNV-NLDIPAAIPVDTMDVN-PNTMENLSVDK 237

Query: 575 VTNRFNSKSKCNARSYSYTLP 637
           V N FN+ +  N+ +Y+  LP
Sbjct: 238 VNNMFNTPNYLNSVNYTDNLP 258


>UniRef50_Q231M3 Cluster: Tubulin-tyrosine ligase family protein;
           n=1; Tetrahymena thermophila SB210|Rep: Tubulin-tyrosine
           ligase family protein - Tetrahymena thermophila SB210
          Length = 993

 Score = 33.1 bits (72), Expect = 5.9
 Identities = 34/148 (22%), Positives = 62/148 (41%)
 Frame = +2

Query: 182 NKLLTRYNKRRAHRDWETKPPGEIKKPYERIKRKKMAMLLGYSGVEYYGMQRNPGVQTIX 361
           N L  +   ++ ++  E +   +++   + IK+KK+        ++      N   + I 
Sbjct: 74  NNLKRKVKTQKVNQTKENQQTSQVQISSQEIKQKKLIHSAEDIDLQVKQFDVNANAEAIK 133

Query: 362 XXXXXXXXXXXYITQEDFENAQNAQFQRSSRTDKGVSAAEQVVSLKLPLEVNVEEINKRL 541
                       I QED EN +N Q QR  + +K         + K  L+ NV + N +L
Sbjct: 134 LEQLKKIDEAKAI-QEDLEN-RNKQRQRDMKLEKLPLNLSN--NNKKSLQ-NVSKRNPQL 188

Query: 542 PETIKVFAVKRVTNRFNSKSKCNARSYS 625
            ET+ +++      +   KS  N +SYS
Sbjct: 189 AETLDIYSQSSGIYQIMQKSLLNGQSYS 216


>UniRef50_A5E087 Cluster: Protein POS5; n=2; Saccharomycetales|Rep:
           Protein POS5 - Lodderomyces elongisporus (Yeast)
           (Saccharomyces elongisporus)
          Length = 535

 Score = 33.1 bits (72), Expect = 5.9
 Identities = 20/61 (32%), Positives = 30/61 (49%), Gaps = 7/61 (11%)
 Frame = +2

Query: 161 KSIDIVPNKLLTRYNKRRAHR----DWETKPPGEI---KKPYERIKRKKMAMLLGYSGVE 319
           +S + +P   L  Y K + HR     W T PP  +   KKP++   R+ M  L+ +  VE
Sbjct: 87  ESCENLPKARLPDYVKSQQHRLFNIIWRTSPPKNVLMVKKPWDATVREAMIQLINHLHVE 146

Query: 320 Y 322
           Y
Sbjct: 147 Y 147


>UniRef50_P56144 Cluster: tRNA pseudouridine synthase A; n=4;
           Helicobacter|Rep: tRNA pseudouridine synthase A -
           Helicobacter pylori (Campylobacter pylori)
          Length = 242

 Score = 33.1 bits (72), Expect = 5.9
 Identities = 26/84 (30%), Positives = 41/84 (48%), Gaps = 7/84 (8%)
 Frame = +2

Query: 404 QEDFENAQNAQFQRS-----SRTDKGVSAAEQVVSLKLPLEVNVEEINKRL-PETIKVFA 565
           Q+  E+A NA   +S      RTDKGV A  QV+S   P   N  ++   L P+      
Sbjct: 28  QDKIEDALNALGIKSVVIAAGRTDKGVHANNQVLSFHAPKHWNAAKLFYYLAPKLAPHIV 87

Query: 566 VKRVTNR-FNSKSKCNARSYSYTL 634
           +K++  + F+++     R+Y Y L
Sbjct: 88  LKKLEEKNFHARFDAQKRAYRYLL 111


>UniRef50_Q0F2X2 Cluster: Pseudouridylate synthase; n=1;
           Mariprofundus ferrooxydans PV-1|Rep: Pseudouridylate
           synthase - Mariprofundus ferrooxydans PV-1
          Length = 267

 Score = 32.7 bits (71), Expect = 7.7
 Identities = 13/35 (37%), Positives = 20/35 (57%)
 Frame = +2

Query: 530 NKRLPETIKVFAVKRVTNRFNSKSKCNARSYSYTL 634
           N  LP+ I+V  V+ V   F+++  C  RSY Y +
Sbjct: 91  NSHLPDEIRVVGVRAVAADFHARFACRGRSYRYQI 125


>UniRef50_A7C1F2 Cluster: tRNA pseudouridine synthase A; n=1;
           Beggiatoa sp. PS|Rep: tRNA pseudouridine synthase A -
           Beggiatoa sp. PS
          Length = 272

 Score = 32.7 bits (71), Expect = 7.7
 Identities = 18/67 (26%), Positives = 31/67 (46%), Gaps = 4/67 (5%)
 Frame = +2

Query: 446 SSRTDKGVSAAEQVVSLKLPLEVNVEE----INKRLPETIKVFAVKRVTNRFNSKSKCNA 613
           + RTD GV A  QV+   + ++ +        N  LP  + +   + V N F+++    A
Sbjct: 47  AGRTDTGVHAIGQVIHADVTVQRSTRSWVLGTNSNLPIDVSMLWAQSVDNNFHARFSAQA 106

Query: 614 RSYSYTL 634
           R Y Y +
Sbjct: 107 RHYRYII 113


>UniRef50_A2U011 Cluster: Pseudouridylate synthase; n=2;
           Polaribacter|Rep: Pseudouridylate synthase -
           Polaribacter dokdonensis MED152
          Length = 260

 Score = 32.7 bits (71), Expect = 7.7
 Identities = 20/65 (30%), Positives = 29/65 (44%), Gaps = 4/65 (6%)
 Frame = +2

Query: 446 SSRTDKGVSAAEQVVSL----KLPLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNA 613
           + RTD  VSA   +  L     L  +V + E+N  LP   K + V  V  +FN  +    
Sbjct: 52  AGRTDAKVSANRYLFQLFTNEVLQQDVFLNELNSNLPADFKAYTVSEVATKFNIINAPKI 111

Query: 614 RSYSY 628
           + Y Y
Sbjct: 112 KEYHY 116


>UniRef50_Q54I97 Cluster: Pseudouridylate synthase; n=1;
           Dictyostelium discoideum AX4|Rep: Pseudouridylate
           synthase - Dictyostelium discoideum AX4
          Length = 491

 Score = 32.7 bits (71), Expect = 7.7
 Identities = 20/78 (25%), Positives = 35/78 (44%)
 Frame = +2

Query: 263 YERIKRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQ 442
           +++  ++ +A  L Y G  ++G       Q              ++      + + A + 
Sbjct: 79  FDKCYKRHVAFKLSYVGWPFFGF----AAQDCSEETIENYLIKAFLKTSLIPDIKTANYF 134

Query: 443 RSSRTDKGVSAAEQVVSL 496
           +S RTDKGVSA  QV+SL
Sbjct: 135 KSGRTDKGVSAYGQVISL 152


>UniRef50_A7RKL3 Cluster: Predicted protein; n=2; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 639

 Score = 32.7 bits (71), Expect = 7.7
 Identities = 23/96 (23%), Positives = 43/96 (44%)
 Frame = +2

Query: 26  VAGKVQEDNCKREKHGNS*KNILAITSARLLSVMEAADVTKDEENKSIDIVPNKLLTRYN 205
           +  +   +  KR+ H    K      S +   + E    T +++N+  D +  K    +N
Sbjct: 300 ITNRGHNEGNKRKGHNERRKETEPKESEKRNKLTELDGATHNKQNE--DKIDEKNENEHN 357

Query: 206 KRRAHRDWETKPPGEIKKPYERIKRKKMAMLLGYSG 313
           K   H + ++   G++ K  ERI++K+ A   G SG
Sbjct: 358 KLNEHCEGDSHNEGKMDKENERIEQKEDATKSGASG 393


>UniRef50_Q96KH5 Cluster: HEIL2; n=1; Homo sapiens|Rep: HEIL2 - Homo
           sapiens (Human)
          Length = 225

 Score = 32.7 bits (71), Expect = 7.7
 Identities = 15/46 (32%), Positives = 25/46 (54%)
 Frame = -3

Query: 173 YRLTYFLHLSLRRQLPLRTASVRLLWLKYFFMNSHAFLVCNYPLVL 36
           +RL + +H S    L   ++ +  LWL Y+F  S AF + ++ L L
Sbjct: 148 FRLNFHVHHSTESTLLKNSSDLPCLWLNYYFNLSAAFYIFDHSLFL 193


>UniRef50_Q8D2P5 Cluster: tRNA pseudouridine synthase A; n=1;
           Wigglesworthia glossinidia endosymbiont of Glossina
           brevipalpis|Rep: tRNA pseudouridine synthase A -
           Wigglesworthia glossinidia brevipalpis
          Length = 264

 Score = 32.7 bits (71), Expect = 7.7
 Identities = 30/123 (24%), Positives = 52/123 (42%), Gaps = 5/123 (4%)
 Frame = +2

Query: 281 KKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFE-NAQNAQFQRSSRT 457
           KK+A  + Y G  Y G Q    + +I            Y+    F+ + +  +   + RT
Sbjct: 2   KKLAAGISYQGNNYCGWQSQKNIISIQE----------YVELALFKFSGEKIKIYCAGRT 51

Query: 458 DKGVSAAEQVVSLKLPLEVNVEE----INKRLPETIKVFAVKRVTNRFNSKSKCNARSYS 625
           D  V A  QVV     ++ +  +    +N  LP  I +  V +V N F+++    A+ Y 
Sbjct: 52  DAKVHALLQVVHFYTDIKRSYRQWILGVNSYLPYDISIMWVIKVHNNFHARYSAIAKKYL 111

Query: 626 YTL 634
           Y +
Sbjct: 112 YLI 114


>UniRef50_P47428 Cluster: tRNA pseudouridine synthase A; n=3;
           Mycoplasma|Rep: tRNA pseudouridine synthase A -
           Mycoplasma genitalium
          Length = 244

 Score = 32.7 bits (71), Expect = 7.7
 Identities = 17/67 (25%), Positives = 35/67 (52%), Gaps = 4/67 (5%)
 Frame = +2

Query: 446 SSRTDKGVSAAEQVVSLKLPLEVNVEEINKRLPETIKVFAVKR----VTNRFNSKSKCNA 613
           S RTDKGV A  Q   + +  E+N+  + +++ + IK   + +    V + F+++ +   
Sbjct: 48  SGRTDKGVHAINQTFHVDINGEINLNLLIRKINQLIKPHCIVKTLVLVNDSFHARFQVKT 107

Query: 614 RSYSYTL 634
           + Y Y +
Sbjct: 108 KVYEYLI 114


>UniRef50_Q8CY46 Cluster: tRNA pseudouridine synthase A; n=3;
           Bifidobacterium|Rep: tRNA pseudouridine synthase A -
           Bifidobacterium longum
          Length = 303

 Score = 32.7 bits (71), Expect = 7.7
 Identities = 20/72 (27%), Positives = 32/72 (44%)
 Frame = +2

Query: 299 LGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTDKGVSAA 478
           L Y G  +YG  + P ++T+             +  +D   A+  +   + RTD GV A+
Sbjct: 8   LAYDGGGFYGWAKQPNLRTVQGTIEDALHKVLRVPTDD--AAEPLRLTVAGRTDTGVHAS 65

Query: 479 EQVVSLKLPLEV 514
            QV  L +  EV
Sbjct: 66  HQVAHLDVSDEV 77


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 605,115,908
Number of Sequences: 1657284
Number of extensions: 11552404
Number of successful extensions: 35125
Number of sequences better than 10.0: 197
Number of HSP's better than 10.0 without gapping: 33869
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 35005
length of database: 575,637,011
effective HSP length: 97
effective length of database: 414,880,463
effective search space used: 48126133708
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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