BLASTX 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= bmov10g05 (643 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_UPI00015B411C Cluster: PREDICTED: similar to pseudourid... 159 5e-38 UniRef50_UPI0000D554D8 Cluster: PREDICTED: similar to CG4159-PA;... 154 1e-36 UniRef50_Q9VDK6 Cluster: CG4159-PA; n=4; Diptera|Rep: CG4159-PA ... 151 1e-35 UniRef50_UPI0000DB712C Cluster: PREDICTED: similar to CG4159-PA;... 146 5e-34 UniRef50_Q4T6B0 Cluster: Chromosome undetermined SCAF8839, whole... 118 9e-26 UniRef50_Q9Y606 Cluster: tRNA pseudouridine synthase A; n=29; Eu... 107 2e-22 UniRef50_Q6CC39 Cluster: tRNA pseudouridine synthase 1; n=1; Yar... 104 2e-21 UniRef50_A7RII9 Cluster: Predicted protein; n=3; Eumetazoa|Rep: ... 103 4e-21 UniRef50_A7NVQ8 Cluster: Chromosome chr18 scaffold_1, whole geno... 101 1e-20 UniRef50_Q4P397 Cluster: Putative uncharacterized protein; n=1; ... 101 1e-20 UniRef50_Q54FA0 Cluster: TRNA pseudouridylate synthase; n=1; Dic... 100 3e-20 UniRef50_A2X849 Cluster: Putative uncharacterized protein; n=4; ... 99 1e-19 UniRef50_Q9LN29 Cluster: F14O10.3 protein; n=3; Arabidopsis thal... 97 2e-19 UniRef50_Q9XXN0 Cluster: Putative uncharacterized protein pus-1;... 96 7e-19 UniRef50_Q7S319 Cluster: Putative uncharacterized protein NCU075... 95 1e-18 UniRef50_Q12211 Cluster: tRNA pseudouridine synthase 1; n=7; Sac... 94 2e-18 UniRef50_O94396 Cluster: tRNA pseudouridine synthase 1; n=1; Sch... 94 2e-18 UniRef50_UPI00004993EF Cluster: tRNA pseudouridine synthase; n=1... 93 7e-18 UniRef50_A7TTG9 Cluster: Putative uncharacterized protein; n=1; ... 91 2e-17 UniRef50_Q0U5E9 Cluster: Putative uncharacterized protein; n=1; ... 91 2e-17 UniRef50_Q2H827 Cluster: Putative uncharacterized protein; n=1; ... 90 4e-17 UniRef50_Q3KZ66 Cluster: Pseudouridylate synthase; n=3; Schistos... 89 1e-16 UniRef50_A6SDF5 Cluster: Putative uncharacterized protein; n=2; ... 89 1e-16 UniRef50_P53167 Cluster: tRNA pseudouridine synthase 2; n=2; Sac... 86 6e-16 UniRef50_Q6FJJ6 Cluster: Similar to sp|P53167 Saccharomyces cere... 80 4e-14 UniRef50_Q00ST8 Cluster: TRNA pseudouridylate synthase; n=2; Ost... 79 7e-14 UniRef50_A2QZ58 Cluster: Putative frameshift; n=1; Aspergillus n... 77 5e-13 UniRef50_Q5K777 Cluster: Pseudouridylate synthase, putative; n=2... 74 3e-12 UniRef50_A7NY39 Cluster: Chromosome chr6 scaffold_3, whole genom... 73 6e-12 UniRef50_Q4D3D3 Cluster: Putative uncharacterized protein; n=3; ... 72 1e-11 UniRef50_O22928 Cluster: Putative tRNA pseudouridine synthase; n... 72 1e-11 UniRef50_Q1XD12 Cluster: TRNA pseudouridine synthase; n=1; Pneum... 70 4e-11 UniRef50_O94295 Cluster: tRNA pseudouridine synthase 2; n=1; Sch... 70 4e-11 UniRef50_Q59S63 Cluster: tRNA pseudouridine synthase 1; n=2; Sac... 67 3e-10 UniRef50_Q10LR0 Cluster: TRNA pseudouridine synthase family prot... 65 2e-09 UniRef50_A2XGH5 Cluster: Putative uncharacterized protein; n=1; ... 65 2e-09 UniRef50_Q8SS41 Cluster: Pseudouridylate synthase; n=1; Encephal... 65 2e-09 UniRef50_O74451 Cluster: Pseudouridylate synthase; n=1; Schizosa... 63 5e-09 UniRef50_A5ULI2 Cluster: Pseudouridylate synthase; n=1; Methanob... 63 5e-09 UniRef50_A4S8M4 Cluster: Predicted protein; n=2; Ostreococcus|Re... 61 3e-08 UniRef50_Q54TQ3 Cluster: Putative uncharacterized protein; n=1; ... 60 6e-08 UniRef50_A4RAI8 Cluster: Putative uncharacterized protein; n=1; ... 59 8e-08 UniRef50_A3F4X8 Cluster: TRNA pseudouridine synthase A; n=1; Tae... 58 2e-07 UniRef50_A6RCJ6 Cluster: Putative uncharacterized protein; n=1; ... 58 2e-07 UniRef50_A2SU30 Cluster: Pseudouridylate synthase; n=1; Methanoc... 58 2e-07 UniRef50_O26928 Cluster: tRNA pseudouridine synthase A; n=1; Met... 58 2e-07 UniRef50_Q54LM5 Cluster: Putative uncharacterized protein; n=1; ... 55 2e-06 UniRef50_Q4Q9E9 Cluster: Pseudouridylate synthase-like protein; ... 55 2e-06 UniRef50_A2QE34 Cluster: Catalytic activity: tRNA uridine <=> tR... 54 3e-06 UniRef50_Q2NHB4 Cluster: Pseudouridylate synthase; n=1; Methanos... 54 3e-06 UniRef50_A2DE30 Cluster: tRNA pseudouridine synthase family prot... 54 4e-06 UniRef50_Q22TA6 Cluster: Pseudouridylate synthase; n=1; Tetrahym... 53 5e-06 UniRef50_A7ASP1 Cluster: tRNA pseudouridine synthase, putative; ... 51 2e-05 UniRef50_Q18DQ1 Cluster: Pseudouridylate synthase; n=1; Haloquad... 51 2e-05 UniRef50_A7D6F0 Cluster: tRNA pseudouridine synthase; n=1; Halor... 51 3e-05 UniRef50_Q8U2C1 Cluster: tRNA pseudouridine synthase A; n=4; The... 51 3e-05 UniRef50_A0DFY8 Cluster: Pseudouridylate synthase; n=1; Parameci... 50 4e-05 UniRef50_Q8R601 Cluster: tRNA pseudouridine synthase A; n=3; Fus... 50 4e-05 UniRef50_UPI00015BE519 Cluster: UPI00015BE519 related cluster; n... 50 5e-05 UniRef50_UPI0000DB7775 Cluster: PREDICTED: similar to CG3045-PA;... 50 5e-05 UniRef50_A5PKS2 Cluster: LOC100101318 protein; n=4; Xenopus|Rep:... 50 5e-05 UniRef50_Q5UXW0 Cluster: tRNA pseudouridine synthase A; n=3; Hal... 50 6e-05 UniRef50_Q5NG36 Cluster: tRNA pseudouridine synthase A; n=11; Fr... 50 6e-05 UniRef50_Q4Q3H7 Cluster: Putative uncharacterized protein; n=3; ... 49 8e-05 UniRef50_A2E6F9 Cluster: tRNA pseudouridine synthase family prot... 48 1e-04 UniRef50_A0DJ25 Cluster: Pseudouridylate synthase; n=1; Parameci... 48 2e-04 UniRef50_Q8TU65 Cluster: tRNA pseudouridine synthase A; n=5; Arc... 48 2e-04 UniRef50_A0E7K0 Cluster: Pseudouridylate synthase; n=1; Parameci... 48 3e-04 UniRef50_Q8XLQ0 Cluster: tRNA pseudouridine synthase A 1; n=4; C... 48 3e-04 UniRef50_A2FDS7 Cluster: tRNA pseudouridine synthase family prot... 47 3e-04 UniRef50_Q64EQ0 Cluster: Pseudouridylate synthase; n=1; uncultur... 47 3e-04 UniRef50_P70830 Cluster: tRNA pseudouridine synthase A; n=3; Bor... 47 3e-04 UniRef50_Q9UTB3 Cluster: Pseudouridylate synthase; n=1; Schizosa... 46 6e-04 UniRef50_Q4UIU5 Cluster: Pseudouridylate synthase; n=2; Theileri... 46 8e-04 UniRef50_Q6F1W2 Cluster: tRNA pseudouridine synthase A; n=3; Mol... 46 8e-04 UniRef50_Q8KDR7 Cluster: tRNA pseudouridine synthase A; n=9; Chl... 46 8e-04 UniRef50_Q1FEL6 Cluster: Pseudouridylate synthase; n=1; Clostrid... 45 0.001 UniRef50_A7HCM5 Cluster: tRNA-pseudouridine synthase I; n=2; Ana... 45 0.001 UniRef50_A0LIV1 Cluster: Pseudouridylate synthase; n=1; Syntroph... 45 0.001 UniRef50_Q250I7 Cluster: Pseudouridylate synthase; n=2; Desulfit... 44 0.002 UniRef50_Q0W2P8 Cluster: Pseudouridylate synthase; n=1; uncultur... 44 0.002 UniRef50_Q8DWH1 Cluster: tRNA pseudouridine synthase A; n=42; La... 44 0.002 UniRef50_UPI00015B40A8 Cluster: PREDICTED: similar to pseudourid... 44 0.004 UniRef50_A6DAN4 Cluster: Pseudouridylate synthase; n=1; Caminiba... 44 0.004 UniRef50_Q7QV27 Cluster: GLP_180_17283_16483; n=1; Giardia lambl... 44 0.004 UniRef50_O66953 Cluster: tRNA pseudouridine synthase A; n=1; Aqu... 44 0.004 UniRef50_UPI0000E87E98 Cluster: tRNA pseudouridine synthase A; n... 43 0.007 UniRef50_Q1IRQ4 Cluster: Pseudouridylate synthase; n=2; Acidobac... 43 0.007 UniRef50_A0YB03 Cluster: Pseudouridylate synthase; n=10; Gammapr... 43 0.007 UniRef50_Q4D8T5 Cluster: Pseudouridylate synthase I, putative; n... 43 0.007 UniRef50_Q5L3Q7 Cluster: tRNA pseudouridine synthase A; n=11; Ba... 43 0.007 UniRef50_A7PC02 Cluster: Chromosome chr2 scaffold_11, whole geno... 42 0.010 UniRef50_A5E2I9 Cluster: Pseudouridylate synthase; n=4; Saccharo... 42 0.010 UniRef50_A7I4S8 Cluster: tRNA pseudouridine synthase A; n=1; Can... 42 0.010 UniRef50_Q6DI24 Cluster: Zgc:56653 protein; n=2; Danio rerio|Rep... 42 0.013 UniRef50_Q57WP9 Cluster: Pseudouridylate synthase I, putative; n... 42 0.013 UniRef50_Q6MDE3 Cluster: tRNA pseudouridine synthase A 2; n=1; C... 42 0.013 UniRef50_Q583N7 Cluster: Pseudouridylate synthase; n=1; Trypanos... 42 0.017 UniRef50_Q17C60 Cluster: Pseudouridylate synthase; n=2; Culicida... 42 0.017 UniRef50_Q7RDA0 Cluster: Putative uncharacterized protein PY0552... 41 0.022 UniRef50_Q6C194 Cluster: Pseudouridylate synthase; n=1; Yarrowia... 41 0.022 UniRef50_Q2FT01 Cluster: Pseudouridylate synthase; n=1; Methanos... 41 0.022 UniRef50_Q9PPV4 Cluster: tRNA pseudouridine synthase A; n=1; Ure... 41 0.022 UniRef50_Q8TWZ3 Cluster: tRNA pseudouridine synthase A; n=1; Met... 41 0.022 UniRef50_O28544 Cluster: tRNA pseudouridine synthase A; n=1; Arc... 41 0.022 UniRef50_Q654A2 Cluster: Pseudouridylate synthase; n=3; Oryza sa... 41 0.029 UniRef50_Q5CPW7 Cluster: Pus1p-like type II pseudousynthas TruA;... 41 0.029 UniRef50_A3LX03 Cluster: Pseudouridylate synthase; n=4; Saccharo... 41 0.029 UniRef50_A0B7V0 Cluster: Pseudouridylate synthase; n=1; Methanos... 41 0.029 UniRef50_Q057U4 Cluster: Pseudouridylate synthase; n=1; Buchnera... 40 0.039 UniRef50_Q09524 Cluster: Probable tRNA pseudouridine synthase ta... 40 0.039 UniRef50_A4XKB7 Cluster: Pseudouridylate synthase; n=3; Clostrid... 40 0.051 UniRef50_Q8CWM6 Cluster: tRNA pseudouridine synthase A; n=1; Syn... 40 0.051 UniRef50_P31115 Cluster: tRNA pseudouridine synthase 3; n=5; Sac... 40 0.051 UniRef50_Q820P8 Cluster: tRNA pseudouridine synthase A; n=10; Pr... 40 0.067 UniRef50_Q88XU9 Cluster: tRNA pseudouridine synthase A; n=10; La... 40 0.067 UniRef50_Q3ZZP4 Cluster: Pseudouridylate synthase; n=3; Dehaloco... 39 0.089 UniRef50_Q3Y386 Cluster: Pseudouridylate synthase; n=3; Firmicut... 39 0.089 UniRef50_Q8GUL5 Cluster: Putative uncharacterized protein At5g35... 39 0.089 UniRef50_Q8I0W4 Cluster: TRNA pseudouridine synthase, putative; ... 39 0.089 UniRef50_Q22RZ3 Cluster: TRNA pseudouridine synthase family prot... 39 0.089 UniRef50_A3CXX4 Cluster: Pseudouridylate synthase; n=1; Methanoc... 39 0.089 UniRef50_Q9X1R0 Cluster: tRNA pseudouridine synthase A; n=5; The... 39 0.089 UniRef50_UPI00015653AF Cluster: tRNA-pseudouridine synthase A; n... 39 0.12 UniRef50_UPI000049A0B0 Cluster: pseudouridine synthase; n=1; Ent... 39 0.12 UniRef50_Q8IAP2 Cluster: Putative uncharacterized protein PF08_0... 39 0.12 UniRef50_Q4Q7E9 Cluster: Pseudouridylate synthase; n=5; Trypanos... 39 0.12 UniRef50_Q64XV0 Cluster: tRNA pseudouridine synthase A; n=16; Ba... 39 0.12 UniRef50_Q3A9U9 Cluster: Pseudouridylate synthase; n=1; Carboxyd... 38 0.16 UniRef50_Q08Z59 Cluster: Pseudouridylate synthase; n=2; Cystobac... 38 0.16 UniRef50_Q7MBB9 Cluster: tRNA pseudouridine synthase A; n=1; Glo... 38 0.16 UniRef50_Q9BZE2 Cluster: tRNA pseudouridine synthase 3; n=19; Eu... 38 0.16 UniRef50_A6Q408 Cluster: Pseudouridylate synthase; n=2; unclassi... 38 0.21 UniRef50_A5KCH3 Cluster: Pseudouridylate synthase 1, putative; n... 38 0.21 UniRef50_Q8R7Y7 Cluster: tRNA pseudouridine synthase A; n=9; Clo... 38 0.21 UniRef50_Q7TU07 Cluster: tRNA pseudouridine synthase A; n=1; Pir... 38 0.21 UniRef50_Q4AHD2 Cluster: TRNA pseudouridine synthase; n=1; Chlor... 38 0.27 UniRef50_Q11XU3 Cluster: Pseudouridylate synthase; n=1; Cytophag... 38 0.27 UniRef50_A6TWE8 Cluster: Pseudouridylate synthase; n=4; Clostrid... 37 0.36 UniRef50_A3I2E1 Cluster: TRNA pseudouridine synthase A; n=1; Alg... 37 0.36 UniRef50_Q7M9U3 Cluster: tRNA pseudouridine synthase A; n=2; Wol... 37 0.36 UniRef50_Q72DL8 Cluster: tRNA pseudouridine synthase A; n=2; Des... 37 0.36 UniRef50_Q890R5 Cluster: tRNA pseudouridine synthase A 2; n=11; ... 37 0.36 UniRef50_Q6I3T8 Cluster: tRNA pseudouridine synthase A 2; n=12; ... 37 0.36 UniRef50_Q21IY8 Cluster: Pseudouridylate synthase; n=2; Gammapro... 37 0.48 UniRef50_Q6G7A2 Cluster: tRNA pseudouridine synthase A; n=16; St... 37 0.48 UniRef50_A0ZG49 Cluster: Pseudouridylate synthase; n=3; Cyanobac... 36 0.63 UniRef50_Q9C5K6 Cluster: Pseudouridylate synthase; n=3; core eud... 36 0.63 UniRef50_Q011R7 Cluster: Exopolyphosphatases and related protein... 36 0.63 UniRef50_Q7TU31 Cluster: tRNA pseudouridine synthase A; n=5; Pro... 36 0.63 UniRef50_A6NVS7 Cluster: Pseudouridylate synthase; n=1; Bacteroi... 36 0.83 UniRef50_Q0UN59 Cluster: Putative uncharacterized protein; n=1; ... 36 0.83 UniRef50_Q72I65 Cluster: tRNA pseudouridine synthase A; n=3; The... 36 0.83 UniRef50_Q47HQ7 Cluster: Pseudouridylate synthase; n=1; Dechloro... 36 1.1 UniRef50_A6BIC3 Cluster: Pseudouridylate synthase; n=1; Dorea lo... 36 1.1 UniRef50_Q4SEJ2 Cluster: Pseudouridylate synthase; n=3; Tetraodo... 35 1.5 UniRef50_Q1Q1P7 Cluster: Pseudouridylate synthase; n=1; Candidat... 35 1.5 UniRef50_A7HKV8 Cluster: tRNA pseudouridine synthase A; n=1; Fer... 35 1.5 UniRef50_A7SJV8 Cluster: Predicted protein; n=1; Nematostella ve... 35 1.5 UniRef50_A7ANH8 Cluster: tRNA pseudouridine synthase A family pr... 35 1.5 UniRef50_Q9KTA4 Cluster: tRNA pseudouridine synthase A; n=29; Ga... 35 1.5 UniRef50_Q6I4Q2 Cluster: tRNA pseudouridine synthase A 1; n=14; ... 35 1.5 UniRef50_Q0AUL4 Cluster: Pseudouridylate synthase; n=1; Syntroph... 35 1.9 UniRef50_A5I338 Cluster: Pseudouridylate synthase; n=7; Clostrid... 35 1.9 UniRef50_P60351 Cluster: tRNA pseudouridine synthase A; n=2; Can... 35 1.9 UniRef50_UPI000023D4AE Cluster: hypothetical protein FG10837.1; ... 34 2.5 UniRef50_Q30RV9 Cluster: Pseudouridylate synthase; n=1; Thiomicr... 34 2.5 UniRef50_Q8GB97 Cluster: Pseudouridylate synthase; n=2; Clostrid... 34 2.5 UniRef50_Q1FLK6 Cluster: Pseudouridylate synthase; n=1; Clostrid... 34 2.5 UniRef50_A7I1Z3 Cluster: tRNA pseudouridine synthase A; n=1; Cam... 34 2.5 UniRef50_A0RNY9 Cluster: Pseudouridylate synthase; n=2; Campylob... 34 2.5 UniRef50_A5E5W9 Cluster: Putative uncharacterized protein; n=1; ... 34 2.5 UniRef50_Q6MEE7 Cluster: tRNA pseudouridine synthase A 1; n=1; C... 34 2.5 UniRef50_UPI0000E48924 Cluster: PREDICTED: similar to FKSG32, pa... 34 3.4 UniRef50_Q4ALX6 Cluster: Pseudouridylate synthase; n=1; Chlorobi... 34 3.4 UniRef50_Q5CV63 Cluster: Pseudouridylate synthase; n=2; Cryptosp... 34 3.4 UniRef50_A0CKA3 Cluster: Chromosome undetermined scaffold_2, who... 34 3.4 UniRef50_Q30XU3 Cluster: Pseudouridylate synthase; n=2; Desulfov... 33 4.4 UniRef50_A3ZQX0 Cluster: Pseudouridylate synthase; n=2; Bacteria... 33 4.4 UniRef50_Q8ZXR6 Cluster: tRNA pseudouridine synthase A; n=4; Pyr... 33 4.4 UniRef50_Q26G59 Cluster: Pseudouridylate synthase; n=5; Flavobac... 33 5.9 UniRef50_Q1NSM9 Cluster: Putative uncharacterized protein; n=1; ... 33 5.9 UniRef50_Q7QX52 Cluster: Pseudouridylate synthase; n=1; Giardia ... 33 5.9 UniRef50_Q4N208 Cluster: Putative uncharacterized protein; n=1; ... 33 5.9 UniRef50_Q231M3 Cluster: Tubulin-tyrosine ligase family protein;... 33 5.9 UniRef50_A5E087 Cluster: Protein POS5; n=2; Saccharomycetales|Re... 33 5.9 UniRef50_P56144 Cluster: tRNA pseudouridine synthase A; n=4; Hel... 33 5.9 UniRef50_Q0F2X2 Cluster: Pseudouridylate synthase; n=1; Mariprof... 33 7.7 UniRef50_A7C1F2 Cluster: tRNA pseudouridine synthase A; n=1; Beg... 33 7.7 UniRef50_A2U011 Cluster: Pseudouridylate synthase; n=2; Polariba... 33 7.7 UniRef50_Q54I97 Cluster: Pseudouridylate synthase; n=1; Dictyost... 33 7.7 UniRef50_A7RKL3 Cluster: Predicted protein; n=2; Nematostella ve... 33 7.7 UniRef50_Q96KH5 Cluster: HEIL2; n=1; Homo sapiens|Rep: HEIL2 - H... 33 7.7 UniRef50_Q8D2P5 Cluster: tRNA pseudouridine synthase A; n=1; Wig... 33 7.7 UniRef50_P47428 Cluster: tRNA pseudouridine synthase A; n=3; Myc... 33 7.7 UniRef50_Q8CY46 Cluster: tRNA pseudouridine synthase A; n=3; Bif... 33 7.7 >UniRef50_UPI00015B411C Cluster: PREDICTED: similar to pseudouridylate synthase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to pseudouridylate synthase - Nasonia vitripennis Length = 437 Score = 159 bits (386), Expect = 5e-38 Identities = 76/129 (58%), Positives = 92/129 (71%) Frame = +2 Query: 257 KPYERIKRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQ 436 +P+ RIKRK AM+LGY G YYGMQRNPG TI IT E FE QN Sbjct: 64 QPFIRIKRKNYAMMLGYCGKNYYGMQRNPGFNTIEEELIKAMLKADLITSEAFETIQNIN 123 Query: 437 FQRSSRTDKGVSAAEQVVSLKLPLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNAR 616 FQR++RTDKGVSA QVVSLKLP + + + IN+ LPE I+VFA+KRVT FNSKS+C+AR Sbjct: 124 FQRAARTDKGVSAVRQVVSLKLPEDPSKDSINETLPEDIRVFAIKRVTKGFNSKSQCDAR 183 Query: 617 SYSYTLPTY 643 +YSYT+PT+ Sbjct: 184 TYSYTMPTF 192 >UniRef50_UPI0000D554D8 Cluster: PREDICTED: similar to CG4159-PA; n=1; Tribolium castaneum|Rep: PREDICTED: similar to CG4159-PA - Tribolium castaneum Length = 588 Score = 154 bits (374), Expect = 1e-36 Identities = 74/137 (54%), Positives = 98/137 (71%) Frame = +2 Query: 230 ETKPPGEIKKPYERIKRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQE 409 ET+ GE+ E+IKR+K A+LLGYSG YYGMQRNP TI YI++E Sbjct: 241 ETEVTGEL---IEKIKRRKFAVLLGYSGTNYYGMQRNPNTPTIEEEFFKALYKNNYISEE 297 Query: 410 DFENAQNAQFQRSSRTDKGVSAAEQVVSLKLPLEVNVEEINKRLPETIKVFAVKRVTNRF 589 +F Q QFQR++RTDKGVSAA QVVSLKL ++++ +IN++LPE I+VF ++RVT F Sbjct: 298 NFTQVQTMQFQRAARTDKGVSAARQVVSLKLREDIDISKINEQLPEVIRVFGIRRVTKGF 357 Query: 590 NSKSKCNARSYSYTLPT 640 NSK +C++RSY+Y LPT Sbjct: 358 NSKVQCDSRSYTYLLPT 374 >UniRef50_Q9VDK6 Cluster: CG4159-PA; n=4; Diptera|Rep: CG4159-PA - Drosophila melanogaster (Fruit fly) Length = 410 Score = 151 bits (366), Expect = 1e-35 Identities = 71/127 (55%), Positives = 92/127 (72%) Frame = +2 Query: 260 PYERIKRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQF 439 P +RIKRKK A+LL Y G YYGMQRNPG+QTI +IT++ FE Q + F Sbjct: 63 PADRIKRKKSAILLSYCGANYYGMQRNPGMQTIEEELFKAMLKHKWITEDSFEQIQISCF 122 Query: 440 QRSSRTDKGVSAAEQVVSLKLPLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARS 619 QR++RTDKGVSAA QV S+KLP E+++E N LP+ I++F V+RVT FN+K +CNAR+ Sbjct: 123 QRAARTDKGVSAARQVCSVKLPEELDLEAFNADLPQQIRLFGVERVTKGFNAKDQCNART 182 Query: 620 YSYTLPT 640 Y+YTLPT Sbjct: 183 YTYTLPT 189 >UniRef50_UPI0000DB712C Cluster: PREDICTED: similar to CG4159-PA; n=1; Apis mellifera|Rep: PREDICTED: similar to CG4159-PA - Apis mellifera Length = 366 Score = 146 bits (353), Expect = 5e-34 Identities = 75/164 (45%), Positives = 101/164 (61%) Frame = +2 Query: 152 EENKSIDIVPNKLLTRYNKRRAHRDWETKPPGEIKKPYERIKRKKMAMLLGYSGVEYYGM 331 E NK I+ V + R + P +I + IK+KK M+LGY G Y GM Sbjct: 4 ETNKQIEDVVEETNKRQIIDESSEIVAKAPKLDIIEKKNNIKKKKFVMVLGYLGKNYSGM 63 Query: 332 QRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTDKGVSAAEQVVSLKLPLE 511 Q N G++TI +IT+ +FE+ + +FQR++RTDKGVSA Q+VSL+LP Sbjct: 64 QINRGIKTIEGSLLSALLKADFITKNEFEDLKEIKFQRAARTDKGVSAVRQIVSLQLPNH 123 Query: 512 VNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYSYTLPTY 643 VN E+INK LP+ IKVF +KRVT FNSK+KC+AR+Y Y LPT+ Sbjct: 124 VNKEDINKHLPKDIKVFDIKRVTRNFNSKNKCDARTYRYVLPTF 167 >UniRef50_Q4T6B0 Cluster: Chromosome undetermined SCAF8839, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome undetermined SCAF8839, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 375 Score = 118 bits (285), Expect = 9e-26 Identities = 66/128 (51%), Positives = 83/128 (64%), Gaps = 4/128 (3%) Frame = +2 Query: 269 RIKRKKMAMLLGYSGVEYYGMQRNPG---VQTIXXXXXXXXXXXXYITQEDFENAQNAQF 439 R +KK+A+LL YSG YYGMQRNPG +TI I + E+ + F Sbjct: 71 RYPKKKVALLLAYSGKGYYGMQRNPGSSEFRTIEDDLVAALVKSGCIPENHAEDMKKMSF 130 Query: 440 QRSSRTDKGVSAAEQVVSLKLPLEVNV-EEINKRLPETIKVFAVKRVTNRFNSKSKCNAR 616 QR +RTDKGVSAA QVVSLKL L ++ E+IN+ LP I+V VKRVT FNSK+ C+AR Sbjct: 131 QRCARTDKGVSAAGQVVSLKLWLIDDLAEKINQHLPPQIRVLGVKRVTQGFNSKNNCDAR 190 Query: 617 SYSYTLPT 640 +Y+Y LPT Sbjct: 191 TYAYMLPT 198 >UniRef50_Q9Y606 Cluster: tRNA pseudouridine synthase A; n=29; Euteleostomi|Rep: tRNA pseudouridine synthase A - Homo sapiens (Human) Length = 427 Score = 107 bits (258), Expect = 2e-22 Identities = 58/130 (44%), Positives = 82/130 (63%), Gaps = 4/130 (3%) Frame = +2 Query: 266 ERIKRKKMAMLLGYSGVEYYGMQRNPG---VQTIXXXXXXXXXXXXYITQEDFENAQNAQ 436 E+ ++K+ +L+ YSG Y+GMQRN G +TI I + E+ + Sbjct: 79 EKPPKRKIVLLMAYSGKGYHGMQRNVGSSQFKTIEDDLVSALVRSGCIPENHGEDMRKMS 138 Query: 437 FQRSSRTDKGVSAAEQVVSLKLPLEVNV-EEINKRLPETIKVFAVKRVTNRFNSKSKCNA 613 FQR +RTDKGVSAA QVVSLK+ L ++ E+IN LP I++ +KRVT FNSK++C+A Sbjct: 139 FQRCARTDKGVSAAGQVVSLKVWLIDDILEKINSHLPSHIRILGLKRVTGGFNSKNRCDA 198 Query: 614 RSYSYTLPTY 643 R+Y Y LPT+ Sbjct: 199 RTYCYLLPTF 208 >UniRef50_Q6CC39 Cluster: tRNA pseudouridine synthase 1; n=1; Yarrowia lipolytica|Rep: tRNA pseudouridine synthase 1 - Yarrowia lipolytica (Candida lipolytica) Length = 528 Score = 104 bits (249), Expect = 2e-21 Identities = 54/148 (36%), Positives = 82/148 (55%), Gaps = 2/148 (1%) Frame = +2 Query: 206 KRRAHRDWETKPPGEIKKPYERIKRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXX 385 K+ RD K G + R ++K+A ++GY G Y+GMQ NP +TI Sbjct: 60 KQGEGRDTRRKTDGPLVADEVRQPKRKVACMIGYCGTGYHGMQLNPPQKTIEGDIFQAFV 119 Query: 386 XXXYITQEDFENAQNAQFQRSSRTDKGVSAAEQVVSLKLPLEVN--VEEINKRLPETIKV 559 I+Q + ++ + + F R++RTDKGV AA V+SLK+ +E VE+IN LPE ++V Sbjct: 120 KAGAISQNNADDPKKSAFMRAARTDKGVHAAGNVISLKMIIEDENIVEKINSHLPEQLRV 179 Query: 560 FAVKRVTNRFNSKSKCNARSYSYTLPTY 643 + V R F + C++R Y Y +PTY Sbjct: 180 WGVSRTNKAFECRKLCSSRVYEYLMPTY 207 >UniRef50_A7RII9 Cluster: Predicted protein; n=3; Eumetazoa|Rep: Predicted protein - Nematostella vectensis Length = 300 Score = 103 bits (247), Expect = 4e-21 Identities = 55/123 (44%), Positives = 72/123 (58%), Gaps = 1/123 (0%) Frame = +2 Query: 278 RKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRT 457 +KK A+L+ Y GV Y GMQ NPGV+TI IT + E FQR +RT Sbjct: 1 KKKCALLISYCGVGYAGMQINPGVRTIEEQLINALHQAEVITDDAKECLGKMSFQRCART 60 Query: 458 DKGVSAAEQVVSLKL-PLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYSYTL 634 DKGVSAA QVVSLK+ L + +IN LP I++F + + T F+ K C+AR+Y Y Sbjct: 61 DKGVSAARQVVSLKISALSSLLPKINSFLPPEIRIFGMIKTTKAFDCKQNCSARTYEYLT 120 Query: 635 PTY 643 PT+ Sbjct: 121 PTF 123 >UniRef50_A7NVQ8 Cluster: Chromosome chr18 scaffold_1, whole genome shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome chr18 scaffold_1, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 378 Score = 101 bits (243), Expect = 1e-20 Identities = 54/132 (40%), Positives = 76/132 (57%), Gaps = 2/132 (1%) Frame = +2 Query: 254 KKPYERIKRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNA 433 KKP R KR+K+A+ Y GV Y GMQ+NPG +TI + ++D + + Sbjct: 32 KKP--RYKRRKIAIFFAYCGVGYQGMQKNPGAKTIEGDLEEALFFSGAVPEQDRGHPKRF 89 Query: 434 QFQRSSRTDKGVSAAEQVVSLKLPLEVN--VEEINKRLPETIKVFAVKRVTNRFNSKSKC 607 + RS+RTDKGVSA QVVS + ++ VE +N LP I++F KRVT FN+K C Sbjct: 90 DWARSARTDKGVSAVGQVVSGRFYIDPPGLVERLNSNLPPQIRIFGFKRVTASFNAKKFC 149 Query: 608 NARSYSYTLPTY 643 + R Y Y +P + Sbjct: 150 DRRRYVYLIPVF 161 >UniRef50_Q4P397 Cluster: Putative uncharacterized protein; n=1; Ustilago maydis|Rep: Putative uncharacterized protein - Ustilago maydis (Smut fungus) Length = 615 Score = 101 bits (242), Expect = 1e-20 Identities = 55/159 (34%), Positives = 88/159 (55%), Gaps = 10/159 (6%) Frame = +2 Query: 197 RYNKRRAHRDWETKPPG--EIKKPYERIKRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXX 370 R ++R R + + P E +R+ ++K+A+ GY G+ Y G+Q NPGV+TI Sbjct: 91 RRDRRGTGRAQDNESPSTCEASASTDRLPKRKVAVKFGYCGIGYSGLQINPGVKTIEGDI 150 Query: 371 XXXXXXXXYITQEDFENAQNAQFQRSSRTDKGVSAAEQVVSLKL--------PLEVNVEE 526 ++ ++ N QR++RTD+GV AA ++SLKL P E V++ Sbjct: 151 FDAFCTAGAVSSDNAVNPNKVGLQRAARTDRGVHAAGNLLSLKLILQPQGLKPGETLVDK 210 Query: 527 INKRLPETIKVFAVKRVTNRFNSKSKCNARSYSYTLPTY 643 +N+ LP I+++ V RV N FN++ C++R Y Y LPTY Sbjct: 211 VNELLPPFIRIWGVTRVQNGFNARQSCDSRMYEYLLPTY 249 >UniRef50_Q54FA0 Cluster: TRNA pseudouridylate synthase; n=1; Dictyostelium discoideum AX4|Rep: TRNA pseudouridylate synthase - Dictyostelium discoideum AX4 Length = 596 Score = 100 bits (240), Expect = 3e-20 Identities = 63/188 (33%), Positives = 96/188 (51%), Gaps = 16/188 (8%) Frame = +2 Query: 128 EAADVTKDEENKSIDIVPNKLLTRYNKRRAHRDWETKPP-----------GEIKKPYERI 274 EA + D+ K + T NKR+ ++ +PP + K + Sbjct: 78 EADEDELDKFEKESESTSTTTTTTENKRKPNQPPPVRPPKLSKEELIELQNKTKITTDES 137 Query: 275 KRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSR 454 ++KK+A++LGYSG Y GMQ+NPG++T+ I+ ++ Q + R +R Sbjct: 138 RKKKVAIILGYSGTNYAGMQKNPGLKTVEEELEHALFRTGGISPDNMYYQQKVDWIRCAR 197 Query: 455 TDKGVSAAEQVVSLKLPL-----EVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARS 619 TDKGVSA VVSLK+ + E +NK LP+ I VF + RV N F++K+ +ARS Sbjct: 198 TDKGVSAIRNVVSLKMEMGPPDFEGMKIALNKELPKDITVFHIMRVNNSFHAKNAVDARS 257 Query: 620 YSYTLPTY 643 Y Y PT+ Sbjct: 258 YIYVTPTH 265 >UniRef50_A2X849 Cluster: Putative uncharacterized protein; n=4; Magnoliophyta|Rep: Putative uncharacterized protein - Oryza sativa subsp. indica (Rice) Length = 588 Score = 98.7 bits (235), Expect = 1e-19 Identities = 52/127 (40%), Positives = 73/127 (57%), Gaps = 2/127 (1%) Frame = +2 Query: 269 RIKRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRS 448 R KR+K+A+LLGY G Y GMQ+NPG +TI + + D + + R+ Sbjct: 45 RYKRRKVAILLGYCGAGYQGMQKNPGARTIEGDLEEALYRAGAVPEADRAAPRRYDWARA 104 Query: 449 SRTDKGVSAAEQVVSLKLPLE--VNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSY 622 +RTDKGVSAA QVVS + ++ V + +N +L I+ F RVTN FN+K C+ R Y Sbjct: 105 ARTDKGVSAAAQVVSGRFYVDPPVFTDRLNAQLAPQIRAFGYVRVTNSFNAKKFCDRRRY 164 Query: 623 SYTLPTY 643 Y LP + Sbjct: 165 VYLLPVF 171 >UniRef50_Q9LN29 Cluster: F14O10.3 protein; n=3; Arabidopsis thaliana|Rep: F14O10.3 protein - Arabidopsis thaliana (Mouse-ear cress) Length = 549 Score = 97.5 bits (232), Expect = 2e-19 Identities = 49/127 (38%), Positives = 74/127 (58%), Gaps = 2/127 (1%) Frame = +2 Query: 269 RIKRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRS 448 + +R+K+A++ + GV Y GMQ+NPG +TI + D +N ++ RS Sbjct: 54 KYRRRKVAIVFAFCGVGYQGMQKNPGAKTIEGELEEALFHAGAVPDADRNKPRNYEWARS 113 Query: 449 SRTDKGVSAAEQVVSLKLPLEVN--VEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSY 622 +RTDKGVSA QVVS + ++ VE +N +LP+ I+VF KRV F+SK C+ R Y Sbjct: 114 ARTDKGVSAVGQVVSGRFYVDPPGFVERLNSKLPDQIRVFGYKRVAPSFSSKKFCDRRRY 173 Query: 623 SYTLPTY 643 Y +P + Sbjct: 174 VYLIPVF 180 >UniRef50_Q9XXN0 Cluster: Putative uncharacterized protein pus-1; n=2; Caenorhabditis|Rep: Putative uncharacterized protein pus-1 - Caenorhabditis elegans Length = 415 Score = 95.9 bits (228), Expect = 7e-19 Identities = 54/138 (39%), Positives = 78/138 (56%), Gaps = 6/138 (4%) Frame = +2 Query: 248 EIKKPYERIKRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQ 427 E KKP R+K+ K AMLLGY G +YYGMQ + TI +IT E Sbjct: 24 EPKKP--RVKQAKYAMLLGYQGKKYYGMQLQKDLPTIESKLLEAMETAGWITTAQKEKPF 81 Query: 428 NAQFQRSSRTDKGVSAAEQVVSLKLPLE------VNVEEINKRLPETIKVFAVKRVTNRF 589 + FQR++RTD+ VSAA Q+ ++LP + +N LP I+VF ++R TN F Sbjct: 82 DFFFQRAARTDRAVSAARQMCGMQLPRDDAKYQAEGAGILNNILPADIRVFGMRRTTNFF 141 Query: 590 NSKSKCNARSYSYTLPTY 643 + + +C+ R+YSYT P++ Sbjct: 142 HPQKQCDHRTYSYTCPSF 159 >UniRef50_Q7S319 Cluster: Putative uncharacterized protein NCU07528.1; n=2; Sordariomycetes|Rep: Putative uncharacterized protein NCU07528.1 - Neurospora crassa Length = 625 Score = 95.5 bits (227), Expect = 1e-18 Identities = 49/128 (38%), Positives = 79/128 (61%), Gaps = 2/128 (1%) Frame = +2 Query: 266 ERIKRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQR 445 ER ++K+A+L+GY+G Y+G+Q N +TI I++ + ++ + + R Sbjct: 116 ERRPKRKVAVLIGYAGTGYHGIQINHKEKTIEGDLFAAFVKAGAISKANADDPKKSSLVR 175 Query: 446 SSRTDKGVSAAEQVVSLKLPLEVN--VEEINKRLPETIKVFAVKRVTNRFNSKSKCNARS 619 +RTDKGV AA V+SLKL +E V++IN LP+ IKV+ ++RVTN F+ C++R Sbjct: 176 CARTDKGVHAAANVLSLKLIVEDEDIVDKINSHLPDQIKVWGIQRVTNGFSCYQACDSRW 235 Query: 620 YSYTLPTY 643 Y Y +P+Y Sbjct: 236 YEYLMPSY 243 >UniRef50_Q12211 Cluster: tRNA pseudouridine synthase 1; n=7; Saccharomycetales|Rep: tRNA pseudouridine synthase 1 - Saccharomyces cerevisiae (Baker's yeast) Length = 544 Score = 94.3 bits (224), Expect = 2e-18 Identities = 46/127 (36%), Positives = 78/127 (61%), Gaps = 2/127 (1%) Frame = +2 Query: 269 RIKRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRS 448 R+ ++K+A+++GY G Y+GMQ NP TI I++++ + + F R+ Sbjct: 71 RLPKRKVAVMVGYCGTGYHGMQYNPPNPTIESALFKAFVEAGAISKDNSNDLKKNGFMRA 130 Query: 449 SRTDKGVSAAEQVVSLKLPLEVN--VEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSY 622 +RTDKGV A ++SLK+ +E ++IN++LPE I+V+ ++RV F+ + C++R Y Sbjct: 131 ARTDKGVHAGGNLISLKMIIEDPDIKQKINEKLPEGIRVWDIERVNKAFDCRKMCSSRWY 190 Query: 623 SYTLPTY 643 Y LPTY Sbjct: 191 EYLLPTY 197 >UniRef50_O94396 Cluster: tRNA pseudouridine synthase 1; n=1; Schizosaccharomyces pombe|Rep: tRNA pseudouridine synthase 1 - Schizosaccharomyces pombe (Fission yeast) Length = 534 Score = 94.3 bits (224), Expect = 2e-18 Identities = 47/128 (36%), Positives = 76/128 (59%), Gaps = 2/128 (1%) Frame = +2 Query: 266 ERIKRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQR 445 E+ ++K+A L+GY G Y+GMQ NP +TI ++ + ++ + R Sbjct: 39 EKKPKRKVACLVGYCGSGYHGMQLNPPSKTIEGDLFDAFVKAGAVSSYNADDPKKVALAR 98 Query: 446 SSRTDKGVSAAEQVVSLKLPLEVN--VEEINKRLPETIKVFAVKRVTNRFNSKSKCNARS 619 ++RTDKGV AA V+SLKL +E +E++N+ LP +I+++ V R N FN ++ C +R Sbjct: 99 AARTDKGVHAAGNVISLKLIMEDEKLIEKVNEHLPPSIRLWDVIRTINSFNPRTYCESRI 158 Query: 620 YSYTLPTY 643 Y Y +PTY Sbjct: 159 YEYMVPTY 166 >UniRef50_UPI00004993EF Cluster: tRNA pseudouridine synthase; n=1; Entamoeba histolytica HM-1:IMSS|Rep: tRNA pseudouridine synthase - Entamoeba histolytica HM-1:IMSS Length = 401 Score = 92.7 bits (220), Expect = 7e-18 Identities = 52/137 (37%), Positives = 83/137 (60%), Gaps = 2/137 (1%) Frame = +2 Query: 239 PPGEIKKPYERIKRKKMAMLLGYSGVEYYG-MQRNPGVQTIXXXXXXXXXXXXYITQEDF 415 P E KK ERIK+ K+A++ Y G Y+G M N +TI I++++ Sbjct: 29 PKEEEKK--ERIKKFKVAVIFSYVGRGYFGLMYLNNNPKTIEGEIENAMYKAKCISEDNK 86 Query: 416 ENAQNAQFQRSSRTDKGVSAAEQVVSLKLPLEVN-VEEINKRLPETIKVFAVKRVTNRFN 592 + + + R +RTDKGVSAA ++SLK+ L+ N +E IN LPETI++ V +V++ FN Sbjct: 87 HDLKKVGWSRCARTDKGVSAANNLISLKMGLDGNYIERINSFLPETIRIQDVVKVSHSFN 146 Query: 593 SKSKCNARSYSYTLPTY 643 +K++ ++R+Y Y P+Y Sbjct: 147 AKTRVDSRTYEYIFPSY 163 >UniRef50_A7TTG9 Cluster: Putative uncharacterized protein; n=1; Vanderwaltozyma polyspora DSM 70294|Rep: Putative uncharacterized protein - Vanderwaltozyma polyspora DSM 70294 Length = 562 Score = 91.5 bits (217), Expect = 2e-17 Identities = 46/128 (35%), Positives = 75/128 (58%), Gaps = 2/128 (1%) Frame = +2 Query: 266 ERIKRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQR 445 +R+ ++K+A+++GY G Y+GMQ NP TI I++ + + + F R Sbjct: 72 KRLPKRKVAVMVGYCGTGYHGMQYNPPNPTIEDALFKAFVQAGAISKANSNDLKKNGFMR 131 Query: 446 SSRTDKGVSAAEQVVSLKLPLE--VNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARS 619 ++RTDKGV A ++SLK+ +E ++IN+ LP IKV+ ++RV F+ + C +R Sbjct: 132 AARTDKGVHAGGNLISLKMIIEDPEIKQKINEELPNGIKVWNIERVNKAFDCRKMCGSRW 191 Query: 620 YSYTLPTY 643 Y Y LPTY Sbjct: 192 YEYLLPTY 199 >UniRef50_Q0U5E9 Cluster: Putative uncharacterized protein; n=1; Phaeosphaeria nodorum|Rep: Putative uncharacterized protein - Phaeosphaeria nodorum (Septoria nodorum) Length = 621 Score = 91.1 bits (216), Expect = 2e-17 Identities = 49/136 (36%), Positives = 78/136 (57%), Gaps = 2/136 (1%) Frame = +2 Query: 242 PGEIKKPYERIKRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFEN 421 P E + ER ++K+A+++GYSG Y GMQ + +TI I++ + ++ Sbjct: 92 PAEEVEAEERRPKRKVAVMIGYSGTGYKGMQIDNKQKTIEGDLFTAFVAAGAISKANADD 151 Query: 422 AQNAQFQRSSRTDKGVSAAEQVVSLKLPLEVN--VEEINKRLPETIKVFAVKRVTNRFNS 595 + + R +RTDKGV AA V+SLKL +E VE+IN L E I+V+ ++R T F+ Sbjct: 152 PKKSSLVRCARTDKGVHAAGNVISLKLIIEEEDIVEKINSHLSEQIRVWGIQRTTGSFSC 211 Query: 596 KSKCNARSYSYTLPTY 643 C++R Y Y +PT+ Sbjct: 212 YQACDSRWYEYLIPTH 227 >UniRef50_Q2H827 Cluster: Putative uncharacterized protein; n=1; Chaetomium globosum|Rep: Putative uncharacterized protein - Chaetomium globosum (Soil fungus) Length = 584 Score = 90.2 bits (214), Expect = 4e-17 Identities = 46/128 (35%), Positives = 77/128 (60%), Gaps = 2/128 (1%) Frame = +2 Query: 266 ERIKRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQR 445 ER ++K+A+L+GY+G Y+G+Q N +TI I++ + ++ + + R Sbjct: 103 ERRPKRKVAVLIGYAGTGYHGIQINHKEKTIEGDLFSAFVAAGAISKANADDPKKSSLVR 162 Query: 446 SSRTDKGVSAAEQVVSLKLPLEVN--VEEINKRLPETIKVFAVKRVTNRFNSKSKCNARS 619 +RTDKGV AA V+SLKL +E V +IN+ LPE I+++ + R +N F++ C +R Sbjct: 163 CARTDKGVHAAGNVLSLKLIVEDEDIVTKINEHLPEQIRIWGIHRTSNGFSAYQACESRW 222 Query: 620 YSYTLPTY 643 Y Y +P+Y Sbjct: 223 YEYLMPSY 230 >UniRef50_Q3KZ66 Cluster: Pseudouridylate synthase; n=3; Schistosoma japonicum|Rep: Pseudouridylate synthase - Schistosoma japonicum (Blood fluke) Length = 334 Score = 88.6 bits (210), Expect = 1e-16 Identities = 49/124 (39%), Positives = 68/124 (54%), Gaps = 1/124 (0%) Frame = +2 Query: 275 KRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSR 454 KR+ A+L+ YSG YYGMQR P TI + E + FQR+S+ Sbjct: 45 KRRNNAILMMYSGWGYYGMQRGPIYPTIEGELSKALFTCGQLVNVTSEEHKKVNFQRASK 104 Query: 455 TDKGVSAAEQVVSLKLPLEVNV-EEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYSYT 631 TDK VSA QV SLKL + ++ ++N LP+ I++ + RVT F+S + C R Y Y Sbjct: 105 TDKYVSALGQVCSLKLYDDADLLNKLNTALPQDIRILDIIRVTRSFSSYNSCTHRVYDYL 164 Query: 632 LPTY 643 LPT+ Sbjct: 165 LPTF 168 >UniRef50_A6SDF5 Cluster: Putative uncharacterized protein; n=2; Sclerotiniaceae|Rep: Putative uncharacterized protein - Botryotinia fuckeliana B05.10 Length = 631 Score = 88.6 bits (210), Expect = 1e-16 Identities = 49/134 (36%), Positives = 76/134 (56%), Gaps = 2/134 (1%) Frame = +2 Query: 248 EIKKPYERIKRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQ 427 E++KP + K+A+++GY+G Y G+Q N +TI I++ + + + Sbjct: 92 EVRKP-----KHKVAVMIGYAGTGYKGLQINTKEKTIEGDMFKAFVAAGAISKANANDPK 146 Query: 428 NAQFQRSSRTDKGVSAAEQVVSLKLPLE--VNVEEINKRLPETIKVFAVKRVTNRFNSKS 601 + R +RTDKGV AA V+SLKL +E VE IN LP+ I+V+ ++R T FN Sbjct: 147 KSALIRCARTDKGVHAAGNVLSLKLIIEDPKVVENINSHLPDQIRVWGIERTTGSFNCYQ 206 Query: 602 KCNARSYSYTLPTY 643 C++R Y Y +PTY Sbjct: 207 MCDSRWYEYLIPTY 220 >UniRef50_P53167 Cluster: tRNA pseudouridine synthase 2; n=2; Saccharomyces cerevisiae|Rep: tRNA pseudouridine synthase 2 - Saccharomyces cerevisiae (Baker's yeast) Length = 370 Score = 86.2 bits (204), Expect = 6e-16 Identities = 45/118 (38%), Positives = 68/118 (57%), Gaps = 1/118 (0%) Frame = +2 Query: 293 MLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTDKGVS 472 MLLGY G YYGMQ NP +TI I++E+ + F ++RTDKGV Sbjct: 1 MLLGYCGSGYYGMQYNPPHKTIEGEILTKLFDVGAISEENSLAPKKNSFMAAARTDKGVH 60 Query: 473 AAEQVVSLKLPL-EVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYSYTLPTY 643 A ++SLK+ L E V ++N LP I+V+ ++ V +FN++S C++R Y Y +P + Sbjct: 61 AMLNLLSLKITLREDTVAKLNAALPPEIRVWGIQPVNKKFNARSACDSRWYQYLIPEF 118 >UniRef50_Q6FJJ6 Cluster: Similar to sp|P53167 Saccharomyces cerevisiae YGL063w PUS2 pseudouridine synthase 2; n=1; Candida glabrata|Rep: Similar to sp|P53167 Saccharomyces cerevisiae YGL063w PUS2 pseudouridine synthase 2 - Candida glabrata (Yeast) (Torulopsis glabrata) Length = 317 Score = 80.2 bits (189), Expect = 4e-14 Identities = 43/124 (34%), Positives = 68/124 (54%), Gaps = 5/124 (4%) Frame = +2 Query: 287 MAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTDKG 466 MA++LGY G Y G+Q NP TI I+Q + ++ + F R++RTDKG Sbjct: 1 MALVLGYLGTGYQGIQYNPPAHTIDNELFKALVATNCISQSNSDDFSKSSFSRATRTDKG 60 Query: 467 VSAAEQVVSLKL-----PLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYSYT 631 V A +V+LK+ P +V E+N+ LP+ I+++ V V +FN++ R Y Y Sbjct: 61 VHALTNLVALKMQRYEVPQQVKA-ELNEILPDDIRIWDVVPVKKKFNARVMAGTRHYRYV 119 Query: 632 LPTY 643 +PT+ Sbjct: 120 IPTF 123 >UniRef50_Q00ST8 Cluster: TRNA pseudouridylate synthase; n=2; Ostreococcus|Rep: TRNA pseudouridylate synthase - Ostreococcus tauri Length = 450 Score = 79.4 bits (187), Expect = 7e-14 Identities = 42/107 (39%), Positives = 62/107 (57%), Gaps = 2/107 (1%) Frame = +2 Query: 275 KRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSR 454 K++K A+ Y G Y GMQRNPGV+TI I+ + + Q+ R++R Sbjct: 40 KKRKCALTFAYVGAGYAGMQRNPGVRTIEGELEGAIARAGGISDANAGDFAKVQWTRAAR 99 Query: 455 TDKGVSAAEQVVSLKLPLEVN--VEEINKRLPETIKVFAVKRVTNRF 589 TDKGVSA QV++LK+ +E + + IN+ LPE +VF + RVT + Sbjct: 100 TDKGVSAVGQVIALKMVMEPDGMLARINEALPERFEVFGIDRVTGGY 146 >UniRef50_A2QZ58 Cluster: Putative frameshift; n=1; Aspergillus niger|Rep: Putative frameshift - Aspergillus niger Length = 567 Score = 76.6 bits (180), Expect = 5e-13 Identities = 43/125 (34%), Positives = 71/125 (56%), Gaps = 2/125 (1%) Frame = +2 Query: 266 ERIKRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQR 445 +R +KK+A+LLGYSG Y GMQ + +TI I++ + + + + R Sbjct: 114 QRRPKKKVAVLLGYSGTGYKGMQLSETEKTIEGELFAAFVAAGAISKANATDPKKSSLVR 173 Query: 446 SSRTDKGVSAAEQVVSLKLPLEVN--VEEINKRLPETIKVFAVKRVTNRFNSKSKCNARS 619 +RTDKGV AA +VSLKL +E + +++IN++L I+V+ + F+S C++R Sbjct: 174 CARTDKGVHAAGNIVSLKLIVEDDDIIQKINEKLSSQIRVWDILVTNKSFSSYQLCDSRI 233 Query: 620 YSYTL 634 Y Y + Sbjct: 234 YEYLI 238 >UniRef50_Q5K777 Cluster: Pseudouridylate synthase, putative; n=2; Filobasidiella neoformans|Rep: Pseudouridylate synthase, putative - Cryptococcus neoformans (Filobasidiella neoformans) Length = 560 Score = 74.1 bits (174), Expect = 3e-12 Identities = 46/153 (30%), Positives = 79/153 (51%), Gaps = 9/153 (5%) Frame = +2 Query: 212 RAHRDWETKPPGEIKKPYERIKRKKMAMLLGYSGVEYYGMQ-RNPGVQTIXXXXXXXXXX 388 RA R WE P E +R+ +++ A+L+GY G Y GMQ ++ +TI Sbjct: 103 RAQRAWE---PSEKTNGEKRLPKRRCAVLIGYCGTGYQGMQIQDHTDRTIEGEVFAALVK 159 Query: 389 XXYITQEDFENAQNAQFQRSSRTDKGVSAAEQVVSLKLPLEVNVEE--------INKRLP 544 ++ ++ +A+ R++RTD GV AA V+S+K+ E + E +N LP Sbjct: 160 AGAVSADNAIDARKVDIARAARTDAGVHAAGNVISIKMITEPPLPEGFKDVAEYVNTFLP 219 Query: 545 ETIKVFAVKRVTNRFNSKSKCNARSYSYTLPTY 643 + I+++ R FN+++ ++R Y Y LP+Y Sbjct: 220 DQIRMWGWVRTVKSFNARTAADSRIYEYLLPSY 252 >UniRef50_A7NY39 Cluster: Chromosome chr6 scaffold_3, whole genome shotgun sequence; n=2; Vitis vinifera|Rep: Chromosome chr6 scaffold_3, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 504 Score = 72.9 bits (171), Expect = 6e-12 Identities = 47/150 (31%), Positives = 74/150 (49%), Gaps = 14/150 (9%) Frame = +2 Query: 230 ETKPPGEIKKPYERIKRKKMAMLLGYSGVEYYG--MQRNPG-VQTIXXXXXXXXXXXXYI 400 E+ P ++K +E ++KK+ M +GY G Y G MQR+ + TI I Sbjct: 47 ESNPDQSVQK-WESFRKKKVVMRVGYVGTNYRGLQMQRDESSLSTIEGELETAVFKAGGI 105 Query: 401 TQEDFENAQNAQFQRSSRTDKGVSAAEQVVSLKLPLEVNVEE-----------INKRLPE 547 ++ N + RSSRTDKGV + ++SLK+ + N + +N LP Sbjct: 106 RDSNYGNLHKIGWDRSSRTDKGVHSLATMISLKMEIPANAWKEDPNGIALANYVNFHLPN 165 Query: 548 TIKVFAVKRVTNRFNSKSKCNARSYSYTLP 637 IKVF++ F+++ +C+ R YSY LP Sbjct: 166 NIKVFSILPSQRSFDARRECDLRRYSYLLP 195 >UniRef50_Q4D3D3 Cluster: Putative uncharacterized protein; n=3; Trypanosoma|Rep: Putative uncharacterized protein - Trypanosoma cruzi Length = 634 Score = 72.1 bits (169), Expect = 1e-11 Identities = 47/142 (33%), Positives = 73/142 (51%), Gaps = 17/142 (11%) Frame = +2 Query: 269 RIKRKKMAMLLGYSGVEYYGMQRN--PGVQTIXXXXXXXXXXXXYITQEDFENA---QNA 433 ++ ++K+A++ GY G Y G+Q N PG T+ I++E++E Q Sbjct: 96 KLPKRKVAIIFGYVGERYCGLQWNHLPGYPTVEEELLRALHRTGMISKENYEQEKVQQKL 155 Query: 434 QFQRSSRTDKGVSAAEQVVSLKLPL--------EVNVEEINKRL----PETIKVFAVKRV 577 ++R+SRTDKGV A V+SL + L E + +E + L P I V+ + V Sbjct: 156 NWERASRTDKGVHALRNVISLNVMLPYAKGSTTEYDPQEARRILMTVLPHDIIVYEIVPV 215 Query: 578 TNRFNSKSKCNARSYSYTLPTY 643 T FN+ C AR+Y Y LPT+ Sbjct: 216 TRSFNAYMLCGARTYEYYLPTF 237 >UniRef50_O22928 Cluster: Putative tRNA pseudouridine synthase; n=1; Arabidopsis thaliana|Rep: Putative tRNA pseudouridine synthase - Arabidopsis thaliana (Mouse-ear cress) Length = 510 Score = 71.7 bits (168), Expect = 1e-11 Identities = 44/139 (31%), Positives = 70/139 (50%), Gaps = 14/139 (10%) Frame = +2 Query: 263 YERIKRKKMAMLLGYSGVEYYGMQ---RNPGVQTIXXXXXXXXXXXXYITQEDFENAQNA 433 +E ++KK+ + +GY G +Y G+Q +P ++TI I ++ + Sbjct: 57 WESYRKKKVVIRIGYVGTDYRGLQIQRDDPSIKTIEGELEVAIYKAGGIRDSNYGDLHKI 116 Query: 434 QFQRSSRTDKGVSAAEQVVSLKLPLE-----------VNVEEINKRLPETIKVFAVKRVT 580 + RSSRTDKGV + +SLK+ + V + I+K LPE I+VF+V Sbjct: 117 GWARSSRTDKGVHSLATSISLKMEIPETAWKDDPQGTVLAKCISKHLPENIRVFSVLPSN 176 Query: 581 NRFNSKSKCNARSYSYTLP 637 RF+ + +C R YSY LP Sbjct: 177 RRFDPRRECTLRKYSYLLP 195 >UniRef50_Q1XD12 Cluster: TRNA pseudouridine synthase; n=1; Pneumocystis carinii|Rep: TRNA pseudouridine synthase - Pneumocystis carinii Length = 227 Score = 70.1 bits (164), Expect = 4e-11 Identities = 34/84 (40%), Positives = 54/84 (64%), Gaps = 2/84 (2%) Frame = +2 Query: 398 ITQEDFENAQNAQFQRSSRTDKGVSAAEQVVSLKLPLEVN--VEEINKRLPETIKVFAVK 571 I + + ++ + + R++RTD+GV AA V+SLKL +E +E IN+ LPETI+V+ + Sbjct: 21 IAEMNADDPKKSSLNRAARTDRGVHAACNVLSLKLIIEQPNLLERINEALPETIRVWGIS 80 Query: 572 RVTNRFNSKSKCNARSYSYTLPTY 643 R FN ++ C AR Y Y +P+Y Sbjct: 81 RTLKSFNPRTFCEARIYEYLVPSY 104 >UniRef50_O94295 Cluster: tRNA pseudouridine synthase 2; n=1; Schizosaccharomyces pombe|Rep: tRNA pseudouridine synthase 2 - Schizosaccharomyces pombe (Fission yeast) Length = 451 Score = 70.1 bits (164), Expect = 4e-11 Identities = 39/126 (30%), Positives = 70/126 (55%), Gaps = 6/126 (4%) Frame = +2 Query: 284 KMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTDK 463 ++ +LLGYSG Y+G+Q N ++TI Y+ + + A++ R++RTDK Sbjct: 40 RIIILLGYSGYGYHGIQINNPLKTIEGDVVAVLKKLGYLKTNNID-AEHLCIARAARTDK 98 Query: 464 GVSAAEQVVSLKL----PLEVNV--EEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYS 625 GV ++SL L PL++++ E+N+ L I+V++V FN + C +R+Y Sbjct: 99 GVHTLRNLISLNLFVDKPLDISLLKTELNEALCSQIRVWSVFPAPKYFNPRISCESRTYE 158 Query: 626 YTLPTY 643 Y +P++ Sbjct: 159 YLIPSF 164 >UniRef50_Q59S63 Cluster: tRNA pseudouridine synthase 1; n=2; Saccharomycetales|Rep: tRNA pseudouridine synthase 1 - Candida albicans (Yeast) Length = 450 Score = 67.3 bits (157), Expect = 3e-10 Identities = 31/71 (43%), Positives = 49/71 (69%), Gaps = 2/71 (2%) Frame = +2 Query: 437 FQRSSRTDKGVSAAEQVVSLKLPLEVN--VEEINKRLPETIKVFAVKRVTNRFNSKSKCN 610 FQR++RTDKGV AA V+SLK+ +E + +IN LP+ I+++ ++R T F+ + C+ Sbjct: 41 FQRAARTDKGVHAAGNVISLKMIIEDPEIINKINDLLPKQIRIWGIQRATKGFDCRKCCS 100 Query: 611 ARSYSYTLPTY 643 +R Y Y LPT+ Sbjct: 101 SRIYEYLLPTF 111 >UniRef50_Q10LR0 Cluster: TRNA pseudouridine synthase family protein, expressed; n=7; Oryza sativa|Rep: TRNA pseudouridine synthase family protein, expressed - Oryza sativa subsp. japonica (Rice) Length = 516 Score = 64.9 bits (151), Expect = 2e-09 Identities = 40/139 (28%), Positives = 67/139 (48%), Gaps = 14/139 (10%) Frame = +2 Query: 263 YERIKRKKMAMLLGYSGVEYYGMQRNPGVQ---TIXXXXXXXXXXXXYITQEDFENAQNA 433 +E ++K++ + +GY G EY G+Q+ + TI I + ++ Q Sbjct: 66 WESARKKRVVLRVGYVGTEYRGLQKQRELSADSTIESVLETAIFKAGGILESNYGKLQKV 125 Query: 434 QFQRSSRTDKGVSAAEQVVSLKLPLEVNVEE-----------INKRLPETIKVFAVKRVT 580 ++RSSRTDKGV + ++SLK+ + E IN LP+ ++VF+V Sbjct: 126 GWERSSRTDKGVHSLATMISLKMEIPDRAWENDPDGIALSNFINSNLPDNVRVFSVLPAQ 185 Query: 581 NRFNSKSKCNARSYSYTLP 637 F+ + +C R Y Y LP Sbjct: 186 RSFDVRRECLYREYLYLLP 204 >UniRef50_A2XGH5 Cluster: Putative uncharacterized protein; n=1; Oryza sativa (indica cultivar-group)|Rep: Putative uncharacterized protein - Oryza sativa subsp. indica (Rice) Length = 264 Score = 64.9 bits (151), Expect = 2e-09 Identities = 40/139 (28%), Positives = 67/139 (48%), Gaps = 14/139 (10%) Frame = +2 Query: 263 YERIKRKKMAMLLGYSGVEYYGMQRNPGVQ---TIXXXXXXXXXXXXYITQEDFENAQNA 433 +E ++K++ + +GY G EY G+Q+ + TI I + ++ Q Sbjct: 66 WESARKKRVVLRVGYVGTEYRGLQKQRELSADSTIESVLETAIFKAGGILESNYGKLQKV 125 Query: 434 QFQRSSRTDKGVSAAEQVVSLKLPLEVNVEE-----------INKRLPETIKVFAVKRVT 580 ++RSSRTDKGV + ++SLK+ + E IN LP+ ++VF+V Sbjct: 126 GWERSSRTDKGVHSLATMISLKMEIPDRAWENDPDGIALSNFINSNLPDNVRVFSVLPAQ 185 Query: 581 NRFNSKSKCNARSYSYTLP 637 F+ + +C R Y Y LP Sbjct: 186 RSFDVRRECLYREYLYLLP 204 >UniRef50_Q8SS41 Cluster: Pseudouridylate synthase; n=1; Encephalitozoon cuniculi|Rep: Pseudouridylate synthase - Encephalitozoon cuniculi Length = 345 Score = 64.9 bits (151), Expect = 2e-09 Identities = 37/124 (29%), Positives = 66/124 (53%), Gaps = 4/124 (3%) Frame = +2 Query: 284 KMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTDK 463 ++ +L+GY G Y+G+Q N + T+ I++ + + + + SSRTDK Sbjct: 4 RVGLLVGYDGSRYHGLQFNKDLDTVEKKIVECLLRMDAISERNAGDPRKIHIKSSSRTDK 63 Query: 464 GVSAAEQVVSLKLPLEVNVEEIN--KRL--PETIKVFAVKRVTNRFNSKSKCNARSYSYT 631 GV AA +VS+K+ L V+ E ++ + L E I ++ + R+T + +R+Y Y Sbjct: 64 GVHAALNLVSVKIELGVSPELVSGLRELLSKEGIHLYDIVRLTKSIVPSKQAISRTYEYI 123 Query: 632 LPTY 643 +PTY Sbjct: 124 VPTY 127 >UniRef50_O74451 Cluster: Pseudouridylate synthase; n=1; Schizosaccharomyces pombe|Rep: Pseudouridylate synthase - Schizosaccharomyces pombe (Fission yeast) Length = 413 Score = 63.3 bits (147), Expect = 5e-09 Identities = 39/125 (31%), Positives = 63/125 (50%), Gaps = 5/125 (4%) Frame = +2 Query: 278 RKKMAM-LLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSR 454 RK+M ++ Y G + G+Q N V+TI + Q + ++ + + ++R Sbjct: 35 RKRMVYCVVSYRGTGFAGLQYNANVKTIQDTLFQAFARVGAVVQVNADSPKKIRMCSAAR 94 Query: 455 TDKGVSAAEQVVSLKL----PLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSY 622 TDKGV A V+ LK+ PL V +N LP I+V+ + R N F+ + C++R Y Sbjct: 95 TDKGVHAIVNVLGLKVLDNQPLPHVVNLVNDILPPCIRVWKMARTFNSFSPHTVCDSRVY 154 Query: 623 SYTLP 637 Y LP Sbjct: 155 EYWLP 159 >UniRef50_A5ULI2 Cluster: Pseudouridylate synthase; n=1; Methanobrevibacter smithii ATCC 35061|Rep: Pseudouridylate synthase - Methanobrevibacter smithii (strain PS / ATCC 35061 / DSM 861) Length = 290 Score = 63.3 bits (147), Expect = 5e-09 Identities = 38/119 (31%), Positives = 60/119 (50%), Gaps = 1/119 (0%) Frame = +2 Query: 281 KKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTD 460 K+ A+ +GY G ++G QR P ++T+ YI ++ + ++F+ + RTD Sbjct: 2 KRTALKIGYIGTNFHGFQRQPDLRTVEEELIYHLRKLGYI-----DDLKKSRFRIAGRTD 56 Query: 461 KGVSAAEQVVSLKLPLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSK-CNARSYSYTL 634 GV + V+S + EV V EIN LP+ I++ A V RF K + R Y Y L Sbjct: 57 AGVHSLGNVISFQSEKEVRVNEINNSLPDDIQILAKAPV--RFGFKPRYAEMRQYRYVL 113 >UniRef50_A4S8M4 Cluster: Predicted protein; n=2; Ostreococcus|Rep: Predicted protein - Ostreococcus lucimarinus CCE9901 Length = 556 Score = 60.9 bits (141), Expect = 3e-08 Identities = 44/137 (32%), Positives = 64/137 (46%), Gaps = 16/137 (11%) Frame = +2 Query: 275 KRKKMAMLLGYSGVEYYGMQRN---PGVQTIXXXXXXXXXXXXYITQEDFENA--QNAQF 439 K+K +A++L Y G Y G N P T+ I ++ + Q ++ Sbjct: 87 KKKPVAIVLAYVGQGYKGNTHNAQAPRGTTVDDVVEDALFAWGGILMPNYRSRGLQRLKW 146 Query: 440 QRSSRTDKGVSAAEQVVSLKLPLEVNV-----------EEINKRLPETIKVFAVKRVTNR 586 RSSRTDKGVS+ VVSL+ ++ V EI K LPE ++ FAV Sbjct: 147 SRSSRTDKGVSSLCTVVSLRAEIDPEVWTKDVEARETAREITKHLPEDVECFAVYNTPKS 206 Query: 587 FNSKSKCNARSYSYTLP 637 F ++ +C R+Y Y LP Sbjct: 207 FQARRECIMRTYEYLLP 223 >UniRef50_Q54TQ3 Cluster: Putative uncharacterized protein; n=1; Dictyostelium discoideum AX4|Rep: Putative uncharacterized protein - Dictyostelium discoideum AX4 Length = 504 Score = 59.7 bits (138), Expect = 6e-08 Identities = 39/138 (28%), Positives = 69/138 (50%), Gaps = 14/138 (10%) Frame = +2 Query: 269 RIKRKKM--AMLLGYSGVEYYGMQRNPGVQ--TIXXXXXXXXXXXXYITQEDFENAQNAQ 436 +I +KK+ AM+ GY G YYG+ ++ +I +I + + + Sbjct: 83 KINKKKLSVAMVFGYDGTGYYGLGYQVDIKYPSIENLIEKVLFRCGHILPSNVGELKRLK 142 Query: 437 FQRSSRTDKGVSAAEQVVSLKLPLEVN----------VEEINKRLPETIKVFAVKRVTNR 586 + SSRTDKGV + V+S L ++ N ++ IN LP +I++F+ +V+ Sbjct: 143 WSHSSRTDKGVHSLATVISCFLVVDDNTFKNDINQTFIDTINNYLPSSIRLFSACKVSRS 202 Query: 587 FNSKSKCNARSYSYTLPT 640 F ++ K RSY+Y +P+ Sbjct: 203 FQARKKGIERSYNYMVPS 220 >UniRef50_A4RAI8 Cluster: Putative uncharacterized protein; n=1; Magnaporthe grisea|Rep: Putative uncharacterized protein - Magnaporthe grisea (Rice blast fungus) (Pyricularia grisea) Length = 720 Score = 59.3 bits (137), Expect = 8e-08 Identities = 32/88 (36%), Positives = 49/88 (55%) Frame = +2 Query: 266 ERIKRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQR 445 ER +KK+A+L+GY+G Y GMQ N +TI I++ + + + R Sbjct: 107 ERKPKKKVAVLIGYAGTGYKGMQINHFEKTIEGDLFRAFVDAGAISKANASDPKKVSLMR 166 Query: 446 SSRTDKGVSAAEQVVSLKLPLEVNVEEI 529 +RTDKGV AA V+SLKL + + +E+ Sbjct: 167 CARTDKGVHAASNVISLKLIVPLEEKEL 194 Score = 40.3 bits (90), Expect = 0.039 Identities = 16/42 (38%), Positives = 25/42 (59%) Frame = +2 Query: 518 VEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYSYTLPTY 643 V IN LP+ I+V+ + R N F+ C++R Y Y +PT+ Sbjct: 291 VARINSHLPDQIRVWDILRTNNSFSCYQACDSRWYEYLMPTH 332 >UniRef50_A3F4X8 Cluster: TRNA pseudouridine synthase A; n=1; Taenia asiatica|Rep: TRNA pseudouridine synthase A - Taenia asiatica (Asian tapeworm) Length = 123 Score = 57.6 bits (133), Expect = 2e-07 Identities = 30/66 (45%), Positives = 39/66 (59%) Frame = +2 Query: 281 KKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTD 460 +K A+L+ YSGV + GMQRN G +TI YI +E +N FQR+S+TD Sbjct: 57 RKCAILVVYSGVGFCGMQRNEGFRTIEGELMMALCNAGYILEEHMKNPSMICFQRASKTD 116 Query: 461 KGVSAA 478 K VSAA Sbjct: 117 KNVSAA 122 >UniRef50_A6RCJ6 Cluster: Putative uncharacterized protein; n=1; Ajellomyces capsulatus NAm1|Rep: Putative uncharacterized protein - Ajellomyces capsulatus NAm1 Length = 634 Score = 57.6 bits (133), Expect = 2e-07 Identities = 37/99 (37%), Positives = 55/99 (55%), Gaps = 2/99 (2%) Frame = +2 Query: 266 ERIKRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQR 445 +R +KK+A++LGYSG Y GMQ + +TI I++ + + + + R Sbjct: 116 QRRPKKKVAVMLGYSGSGYKGMQLSETEKTIEGDLFTAFVAAGAISKANATDPKKSSLVR 175 Query: 446 SSRTDKGVSAAEQVVSLKLPLEVN--VEEINKRLPETIK 556 +RTDKGV AA VVSLKL +E V++IN L I+ Sbjct: 176 CARTDKGVHAAGNVVSLKLIVEDPNVVQKINGHLSPQIR 214 >UniRef50_A2SU30 Cluster: Pseudouridylate synthase; n=1; Methanocorpusculum labreanum Z|Rep: Pseudouridylate synthase - Methanocorpusculum labreanum (strain ATCC 43576 / DSM 4855 / Z) Length = 281 Score = 57.6 bits (133), Expect = 2e-07 Identities = 37/119 (31%), Positives = 52/119 (43%), Gaps = 1/119 (0%) Frame = +2 Query: 284 KMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTDK 463 K+A L GY G + G Q P +T+ F +A+ A F+ + RTDK Sbjct: 2 KLAFLAGYRGQNFAGSQYQPHKRTVEGEFVAGGIELGL-----FSDAKEAHFRTAGRTDK 56 Query: 464 GVSAAEQVVSLKLPL-EVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYSYTLP 637 GVSA Q+ S+ E+ +E +N LP+ I V F + RSY Y P Sbjct: 57 GVSARRQLFSITTEKPELAIEALNFHLPDDIWCIGAAEVDEEFYPRYAARERSYRYYFP 115 >UniRef50_O26928 Cluster: tRNA pseudouridine synthase A; n=1; Methanothermobacter thermautotrophicus str. Delta H|Rep: tRNA pseudouridine synthase A - Methanobacterium thermoautotrophicum Length = 275 Score = 57.6 bits (133), Expect = 2e-07 Identities = 38/118 (32%), Positives = 55/118 (46%) Frame = +2 Query: 281 KKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTD 460 +K+A+ + Y G Y+G QR P V T+ I E+ + A+FQ + RTD Sbjct: 2 RKIALKVAYIGTNYHGFQRQPDVPTVEGKLLEALEGAGII-----EDPKRARFQIAGRTD 56 Query: 461 KGVSAAEQVVSLKLPLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYSYTL 634 +GV A VS +++V +IN LP I+V A V F + R Y Y L Sbjct: 57 RGVHALGNFVSFFTEEDIHVNQINDLLPRDIRVLAWASVMYPFKVRYPLE-RHYRYIL 113 >UniRef50_Q54LM5 Cluster: Putative uncharacterized protein; n=1; Dictyostelium discoideum AX4|Rep: Putative uncharacterized protein - Dictyostelium discoideum AX4 Length = 615 Score = 54.8 bits (126), Expect = 2e-06 Identities = 37/146 (25%), Positives = 67/146 (45%), Gaps = 16/146 (10%) Frame = +2 Query: 248 EIKKPYERIKRKKMAMLLGYSGVEYYGMQRNPGVQ--TIXXXXXXXXXXXXYITQEDFEN 421 EI++ + +K MA+ Y+G +YYG + ++ I +I E+ N Sbjct: 137 EIEQNLKDKSKKPMALCFAYNGSKYYGSSYSFDIRFPAIENLIEKSLIRNGHIALENIGN 196 Query: 422 AQNAQFQRSSRTDKGVSAAEQVVSLKL--------------PLEVNVEEINKRLPETIKV 559 + + RSSRTDKGV + V+S L P + ++ IN+ LP I++ Sbjct: 197 LKRIKLSRSSRTDKGVHSVSTVISAFLLIDKETERLAQFGTPPQYFIDNINRYLPSDIRL 256 Query: 560 FAVKRVTNRFNSKSKCNARSYSYTLP 637 + + + F ++ +R Y+Y +P Sbjct: 257 ISATKPSRTFRARPASKSRVYNYLVP 282 >UniRef50_Q4Q9E9 Cluster: Pseudouridylate synthase-like protein; n=3; Leishmania|Rep: Pseudouridylate synthase-like protein - Leishmania major Length = 696 Score = 54.8 bits (126), Expect = 2e-06 Identities = 31/82 (37%), Positives = 46/82 (56%), Gaps = 9/82 (10%) Frame = +2 Query: 425 QNAQFQRSSRTDKGVSAAEQVVSLKLPLEVN---------VEEINKRLPETIKVFAVKRV 577 ++ F RS RTD+GV A +VSL +P EV E++N++LP T++V V ++ Sbjct: 78 EHHHFARSCRTDRGVHAIRNMVSLFVPKEVFEKMGQAEGICEKLNRQLPATVRVANVMQL 137 Query: 578 TNRFNSKSKCNARSYSYTLPTY 643 + F + CN R Y Y LP Y Sbjct: 138 SGSFIPRHCCNRRVYRYMLPLY 159 >UniRef50_A2QE34 Cluster: Catalytic activity: tRNA uridine <=> tRNA pseudouridine; n=1; Aspergillus niger|Rep: Catalytic activity: tRNA uridine <=> tRNA pseudouridine - Aspergillus niger Length = 517 Score = 54.0 bits (124), Expect = 3e-06 Identities = 42/147 (28%), Positives = 66/147 (44%), Gaps = 9/147 (6%) Frame = +2 Query: 215 AHRDWETKPPGEIKKPYE----RIKRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXX 382 A + + KPP K E R + +A+ Y G Y G++ G T Sbjct: 81 AEKKKQVKPPKPPKPRREIDPSRYNTRFIALKFAYLGQRYNGLEHANGNATPLPTIEEEM 140 Query: 383 XXXXYITQED---FENAQNAQFQRSSRTDKGVSAAEQVVSLKLPLEV-NVEEINKRLPET 550 T+E + N ++ ++ RTD+GVSA QV+ +++ E+ V +NK LPE Sbjct: 141 YKALRKTRETKPYYINWDGCEYSKAGRTDRGVSAFGQVIGIRVRNELPYVSMLNKVLPED 200 Query: 551 IKVFA-VKRVTNRFNSKSKCNARSYSY 628 I+V A R F+++ C R Y Y Sbjct: 201 IRVLAWCPRPPEGFDARFSCGERHYKY 227 >UniRef50_Q2NHB4 Cluster: Pseudouridylate synthase; n=1; Methanosphaera stadtmanae DSM 3091|Rep: Pseudouridylate synthase - Methanosphaera stadtmanae (strain DSM 3091) Length = 274 Score = 54.0 bits (124), Expect = 3e-06 Identities = 31/119 (26%), Positives = 56/119 (47%) Frame = +2 Query: 281 KKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTD 460 +++A+ + Y G ++G QR P +T+ I E+ A + + RTD Sbjct: 2 RRVALKIAYIGSNFHGYQRQPNYRTVEGELLRVFKETNII-----EDTWTAHYSVAGRTD 56 Query: 461 KGVSAAEQVVSLKLPLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYSYTLP 637 KGV + V+S ++++ ++N LP+ IK+ RV F + R+Y+Y P Sbjct: 57 KGVHSTGNVISFITDEDIHINQLNGLLPDDIKIIGEARVPYGFKVRFPL-TRTYTYIQP 114 >UniRef50_A2DE30 Cluster: tRNA pseudouridine synthase family protein; n=1; Trichomonas vaginalis G3|Rep: tRNA pseudouridine synthase family protein - Trichomonas vaginalis G3 Length = 345 Score = 53.6 bits (123), Expect = 4e-06 Identities = 34/124 (27%), Positives = 61/124 (49%), Gaps = 8/124 (6%) Frame = +2 Query: 293 MLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTDKGVS 472 +L Y G +Y+G+Q+N T+ +++ + N ++ +SRTD GV Sbjct: 31 LLYRYIGTQYHGLQQNIDTHTVEKELFQALISAGFLSDQANCNLNRIKWSEASRTDAGVH 90 Query: 473 AAEQVVSLK------LPLEVNVEEINKRLPETIKVFAVKRVTNR--FNSKSKCNARSYSY 628 A QV+S K + + + INK+LP T + + +T R F ++ +R+Y++ Sbjct: 91 ACAQVLSFKASGLKGICIADIPDLINKQLPRTSDIEIITCITLRRQFYAQKFAESRNYNF 150 Query: 629 TLPT 640 LPT Sbjct: 151 LLPT 154 >UniRef50_Q22TA6 Cluster: Pseudouridylate synthase; n=1; Tetrahymena thermophila SB210|Rep: Pseudouridylate synthase - Tetrahymena thermophila SB210 Length = 481 Score = 53.2 bits (122), Expect = 5e-06 Identities = 34/133 (25%), Positives = 56/133 (42%) Frame = +2 Query: 230 ETKPPGEIKKPYERIKRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQE 409 E K + + +E +++ A+ + Y G+ Y G+ + Sbjct: 95 EQKQNNKKESLFEIYQQQHYALKMSYVGINYQGLAYQQETDNTVEEQLFKALEKTTL--- 151 Query: 410 DFENAQNAQFQRSSRTDKGVSAAEQVVSLKLPLEVNVEEINKRLPETIKVFAVKRVTNRF 589 +N N F RS RTDKGVSA QV+ + L + + E N + I++ +V F Sbjct: 152 -IKNRDNCNFTRSGRTDKGVSALGQVIGITLRTSIKIGE-NIDEIDDIRILGCSKVDPAF 209 Query: 590 NSKSKCNARSYSY 628 N++ C R Y Y Sbjct: 210 NARFDCQKRIYKY 222 >UniRef50_A7ASP1 Cluster: tRNA pseudouridine synthase, putative; n=1; Babesia bovis|Rep: tRNA pseudouridine synthase, putative - Babesia bovis Length = 414 Score = 51.2 bits (117), Expect = 2e-05 Identities = 38/133 (28%), Positives = 56/133 (42%), Gaps = 18/133 (13%) Frame = +2 Query: 293 MLLGYSGVEYYGMQ-----RNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRT 457 ++L Y G Y+G Q + G+ T+ I N Q ++SRT Sbjct: 31 IVLSYIGTNYHGFQIQRDAGDDGIDTVEARVINALVTTDAIHGSHKNNLGKLQLSKASRT 90 Query: 458 DKGVSAAEQVVSLKLPL-------------EVNVEEINKRLPETIKVFAVKRVTNRFNSK 598 DKGV AA + + L + V +N LP+ I+ F V RVT F ++ Sbjct: 91 DKGVHAACTYIGGRFELSHLSAGEPGISKEQCLVSRLNTVLPDDIRCFQVLRVTRGFCAR 150 Query: 599 SKCNARSYSYTLP 637 S C+ R Y Y +P Sbjct: 151 SMCSKRMYEYVIP 163 >UniRef50_Q18DQ1 Cluster: Pseudouridylate synthase; n=1; Haloquadratum walsbyi DSM 16790|Rep: Pseudouridylate synthase - Haloquadratum walsbyi (strain DSM 16790) Length = 276 Score = 51.2 bits (117), Expect = 2e-05 Identities = 30/115 (26%), Positives = 51/115 (44%) Frame = +2 Query: 290 AMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTDKGV 469 A L Y G + G QR P V T+ ++ +++ + + + RTD GV Sbjct: 7 AFRLAYDGRPFSGFQRQPSVPTVEDALFDALDSLDVFNRDT--DSKPSGYAAAGRTDAGV 64 Query: 470 SAAEQVVSLKLPLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYSYTL 634 SA Q V + P +N LP +++ +A V + F++ R+Y+Y L Sbjct: 65 SALRQTVGFECPSWCTPRALNSELPTSVRAWASADVQSGFHATHDALQRTYTYYL 119 >UniRef50_A7D6F0 Cluster: tRNA pseudouridine synthase; n=1; Halorubrum lacusprofundi ATCC 49239|Rep: tRNA pseudouridine synthase - Halorubrum lacusprofundi ATCC 49239 Length = 293 Score = 50.8 bits (116), Expect = 3e-05 Identities = 33/116 (28%), Positives = 50/116 (43%), Gaps = 1/116 (0%) Frame = +2 Query: 290 AMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFE-NAQNAQFQRSSRTDKG 466 A + Y G EY G QR P T+ + + D +A + + RTD G Sbjct: 10 AFRVAYDGREYAGFQRQPHATTVEGTLLRALAKHGILDRGDGPTHATPPGYAAAGRTDAG 69 Query: 467 VSAAEQVVSLKLPLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYSYTL 634 VSA Q V+ + P + N LP +++V+A V F++ R+Y Y L Sbjct: 70 VSAVAQTVAFEAPDWLTPRAFNGHLPGSVRVWAAADVPAGFHATHDAVRRTYRYHL 125 >UniRef50_Q8U2C1 Cluster: tRNA pseudouridine synthase A; n=4; Thermococcaceae|Rep: tRNA pseudouridine synthase A - Pyrococcus furiosus Length = 266 Score = 50.8 bits (116), Expect = 3e-05 Identities = 34/121 (28%), Positives = 60/121 (49%), Gaps = 2/121 (1%) Frame = +2 Query: 284 KMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTDK 463 ++A+ + Y G +++G QR P V+TI +FEN F+ +SRTD+ Sbjct: 2 RVALKIAYDGTKFHGFQRQPNVRTIEGEILRALKDAGI----EFEN-----FKSASRTDR 52 Query: 464 GVSAAEQVVSLKLPLE--VNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYSYTLP 637 GVSA V++L + N +N R+ + + ++ + V F+ + N + Y Y LP Sbjct: 53 GVSARGNVIALSTEDDRIKNPMVLNSRMSD-VWIWGIAEVPEDFHPRFWANTKVYRYYLP 111 Query: 638 T 640 + Sbjct: 112 S 112 >UniRef50_A0DFY8 Cluster: Pseudouridylate synthase; n=1; Paramecium tetraurelia|Rep: Pseudouridylate synthase - Paramecium tetraurelia Length = 414 Score = 50.4 bits (115), Expect = 4e-05 Identities = 36/124 (29%), Positives = 59/124 (47%), Gaps = 6/124 (4%) Frame = +2 Query: 275 KRKKMAMLLGYSGVEYYGMQRNPGVQ-TIXXXXXXXXXXXXYITQEDFENAQNAQFQRSS 451 K ++A L Y G+ Y+G+++ Q TI I +N + + R+ Sbjct: 47 KFTRVAFKLAYVGINYHGLEQQINQQNTIENHLFKALQRVRMI-----DNRDDCNYTRAG 101 Query: 452 RTDKGVSAAEQVVSLKLPL-----EVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNAR 616 RTDKGVSA VV+L + ++ + +N+ LPE I++ V +FN++ C R Sbjct: 102 RTDKGVSAIGNVVALNVRKIGKSDKLYAQILNRVLPEDIQILDECIVDEKFNARYDCIKR 161 Query: 617 SYSY 628 Y Y Sbjct: 162 VYKY 165 >UniRef50_Q8R601 Cluster: tRNA pseudouridine synthase A; n=3; Fusobacterium nucleatum|Rep: tRNA pseudouridine synthase A - Fusobacterium nucleatum subsp. nucleatum Length = 247 Score = 50.4 bits (115), Expect = 4e-05 Identities = 36/125 (28%), Positives = 56/125 (44%), Gaps = 4/125 (3%) Frame = +2 Query: 272 IKRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSS 451 ++RK + + Y G YYG QR P T+ +T+E+ N +A Sbjct: 3 MRRKNIKIEFRYDGSSYYGFQRQPNKITVQGEIEKVLRI---VTKEEI-NLISA-----G 53 Query: 452 RTDKGVSAAEQV----VSLKLPLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARS 619 RTD+GV A QV S +P+E + + LP I + +V+ V FN++ R Sbjct: 54 RTDRGVHANHQVSNFYTSSNIPIEKYKYLLTRALPNDIDILSVEEVDENFNARHNAKMRE 113 Query: 620 YSYTL 634 Y Y + Sbjct: 114 YIYII 118 >UniRef50_UPI00015BE519 Cluster: UPI00015BE519 related cluster; n=1; unknown|Rep: UPI00015BE519 UniRef100 entry - unknown Length = 247 Score = 50.0 bits (114), Expect = 5e-05 Identities = 35/122 (28%), Positives = 54/122 (44%), Gaps = 4/122 (3%) Frame = +2 Query: 281 KKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTD 460 K + + G Y G Q P V TI YI + Q + SRTD Sbjct: 2 KNYKFTISFVGTNYSGWQYQPNVPTIQNEVEEKLY---YIVNKKKPIKQKIRAIGCSRTD 58 Query: 461 KGVSAAEQVVSLKLPLEVNV----EEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYSY 628 KGV A E V ++K+ + ++ + +N LP+ IK+ ++ V FNS+ ++Y Y Sbjct: 59 KGVHAIEFVFNVKMEFDKDLNFLRKALNSALPKDIKIHNIEEVPLEFNSRFDALKKTYIY 118 Query: 629 TL 634 L Sbjct: 119 KL 120 >UniRef50_UPI0000DB7775 Cluster: PREDICTED: similar to CG3045-PA; n=2; Endopterygota|Rep: PREDICTED: similar to CG3045-PA - Apis mellifera Length = 406 Score = 50.0 bits (114), Expect = 5e-05 Identities = 46/164 (28%), Positives = 72/164 (43%), Gaps = 15/164 (9%) Frame = +2 Query: 191 LTRYNKRRAHRDWETKPPGEIKKPYERIKRKKMAMLLG--YSGVEYYGMQRNPGVQTIXX 364 L + NK+ ++D K +KP++ K K +LL Y G +Y G VQ Sbjct: 33 LEKENKQLKNKDIIRKS----QKPFDFSKCNKRHILLKFYYLGWDYNGFV----VQESID 84 Query: 365 XXXXXXXXXXYITQEDFENAQNAQFQRSSRTDKGVSAAEQVVSLKLPLEVNVEE------ 526 I E+ + + + R RTDKGVS+ QV+SL + ++N E+ Sbjct: 85 NTIEEHLFEALIKSCCIESRETSNYHRCGRTDKGVSSFSQVISLDIRSKLNPEDQYKLED 144 Query: 527 -------INKRLPETIKVFAVKRVTNRFNSKSKCNARSYSYTLP 637 +N+ LP I+ A V N F+++ C R+Y Y P Sbjct: 145 ELPYCKILNRLLPSNIRCIAWCPVPNDFSARFNCKFRTYKYFFP 188 >UniRef50_A5PKS2 Cluster: LOC100101318 protein; n=4; Xenopus|Rep: LOC100101318 protein - Xenopus laevis (African clawed frog) Length = 507 Score = 50.0 bits (114), Expect = 5e-05 Identities = 28/81 (34%), Positives = 42/81 (51%), Gaps = 7/81 (8%) Frame = +2 Query: 416 ENAQNAQFQRSSRTDKGVSAAEQVVSLKLPLEVN-------VEEINKRLPETIKVFAVKR 574 E+ Q + + R RTD+GVSA QV+SL L V +N+ LP I+V + Sbjct: 100 ESRQTSNYHRCGRTDRGVSALAQVISLDLRCSAEGKPEIRYVHILNRVLPPDIRVLSWAP 159 Query: 575 VTNRFNSKSKCNARSYSYTLP 637 V F+++ C +R+Y Y P Sbjct: 160 VPPSFSARFSCGSRTYRYLFP 180 >UniRef50_Q5UXW0 Cluster: tRNA pseudouridine synthase A; n=3; Halobacteriaceae|Rep: tRNA pseudouridine synthase A - Haloarcula marismortui (Halobacterium marismortui) Length = 275 Score = 49.6 bits (113), Expect = 6e-05 Identities = 33/115 (28%), Positives = 50/115 (43%) Frame = +2 Query: 290 AMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTDKGV 469 A + Y G Y+G QR P V T+ E E + ++ + RTD GV Sbjct: 3 AYRVAYDGQPYHGFQRQPDVDTVEGRLRSALVRLGVC--ERGEGLPD-RYAAAGRTDAGV 59 Query: 470 SAAEQVVSLKLPLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYSYTL 634 SA Q V+ P ++ N LP ++V+A V F++ R+Y+Y L Sbjct: 60 SARTQTVAFDAPAWLSPAAFNGELPNDVRVWASADVPEDFHATHDAAERTYTYYL 114 >UniRef50_Q5NG36 Cluster: tRNA pseudouridine synthase A; n=11; Francisella tularensis|Rep: tRNA pseudouridine synthase A - Francisella tularensis subsp. tularensis Length = 258 Score = 49.6 bits (113), Expect = 6e-05 Identities = 27/74 (36%), Positives = 40/74 (54%), Gaps = 4/74 (5%) Frame = +2 Query: 425 QNAQFQRSSRTDKGVSAAEQVVSL----KLPLEVNVEEINKRLPETIKVFAVKRVTNRFN 592 QN + + RTD GV A Q+V+ PL +N LP+ IK+ AV++V N FN Sbjct: 41 QNIEVTCAGRTDTGVHATSQIVNFYSNADRPLSAWQRGVNALLPQDIKILAVQQVDNNFN 100 Query: 593 SKSKCNARSYSYTL 634 S+ R+Y+Y + Sbjct: 101 SRFTAINRTYNYII 114 >UniRef50_Q4Q3H7 Cluster: Putative uncharacterized protein; n=3; Leishmania|Rep: Putative uncharacterized protein - Leishmania major Length = 701 Score = 49.2 bits (112), Expect = 8e-05 Identities = 33/98 (33%), Positives = 51/98 (52%), Gaps = 6/98 (6%) Frame = +2 Query: 266 ERIKRK-KMAMLLGYSGVEYYGMQRN--PGVQTIXXXXXXXXXXXXYITQEDFENAQNAQ 436 +R++RK K+ ++ GY G Y G+Q N P T+ I++ +F N + Q Sbjct: 50 KRVRRKQKVGIIFGYVGECYCGLQWNHLPEYPTVEEALMKALFETDMISEVNFSNVKVQQ 109 Query: 437 ---FQRSSRTDKGVSAAEQVVSLKLPLEVNVEEINKRL 541 F+R+SRTDKGV A VVS+ + L + KR+ Sbjct: 110 LLNFERASRTDKGVHALRNVVSVAVMLPYDPSYTKKRV 147 Score = 41.5 bits (93), Expect = 0.017 Identities = 18/39 (46%), Positives = 23/39 (58%) Frame = +2 Query: 527 INKRLPETIKVFAVKRVTNRFNSKSKCNARSYSYTLPTY 643 +N+ LP I V+AV VT FN+ C R Y Y LPT+ Sbjct: 190 LNEALPRDIHVYAVVPVTRSFNAYLNCGGRRYEYYLPTF 228 >UniRef50_A2E6F9 Cluster: tRNA pseudouridine synthase family protein; n=1; Trichomonas vaginalis G3|Rep: tRNA pseudouridine synthase family protein - Trichomonas vaginalis G3 Length = 346 Score = 48.4 bits (110), Expect = 1e-04 Identities = 35/121 (28%), Positives = 53/121 (43%), Gaps = 8/121 (6%) Frame = +2 Query: 305 YSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTDKGVSAAEQ 484 Y G Y+G+Q N V+TI + + ++ + +SRTD GV A Q Sbjct: 39 YIGTGYHGLQYNEKVRTIDSDLFEGLEKSGILPEGSYKRRGKIAWNEASRTDAGVHACGQ 98 Query: 485 VVSLK----LPLEVNV--EEINKRLPE--TIKVFAVKRVTNRFNSKSKCNARSYSYTLPT 640 ++ K +E + E INK LP TIK+ + + F K R Y+Y LP Sbjct: 99 LICFKSYEICDMECSQIPELINKNLPSDSTIKIMSCLCTNSPFPVKDFATHRKYNYLLPL 158 Query: 641 Y 643 + Sbjct: 159 H 159 >UniRef50_A0DJ25 Cluster: Pseudouridylate synthase; n=1; Paramecium tetraurelia|Rep: Pseudouridylate synthase - Paramecium tetraurelia Length = 297 Score = 48.0 bits (109), Expect = 2e-04 Identities = 31/103 (30%), Positives = 52/103 (50%), Gaps = 21/103 (20%) Frame = +2 Query: 398 ITQEDFENAQNAQFQRSSRTDKGVSAAEQVVSLKLPLEVN-------------------- 517 +++ + ++ + R +RTD+GV A VVSLKL ++ Sbjct: 26 VSELNADSIKKIGVSRGARTDRGVHALCNVVSLKLQIDQKYCSSMTNNKLVDKWNIDWDL 85 Query: 518 -VEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYSYTLPTY 643 ++E+N +LP IKV A+K VT FN K + + R Y+Y P++ Sbjct: 86 LIQELNSQLPSDIKVNAIKHVTQSFNVKHQADQRMYNYISPSF 128 >UniRef50_Q8TU65 Cluster: tRNA pseudouridine synthase A; n=5; Archaea|Rep: tRNA pseudouridine synthase A - Methanosarcina acetivorans Length = 269 Score = 48.0 bits (109), Expect = 2e-04 Identities = 34/119 (28%), Positives = 54/119 (45%), Gaps = 2/119 (1%) Frame = +2 Query: 284 KMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTDK 463 ++A+ L Y G E++G Q P V+T+ I E+ ++A + + RTD Sbjct: 2 RVALKLAYIGTEFHGSQIQPNVETVEKELFKALRNLSII-----ESPKSADYTCAGRTDA 56 Query: 464 GVSAAEQVVSL--KLPLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYSYTL 634 GV A QVV+ + P IN LP I +A V F+++ +R Y Y + Sbjct: 57 GVHALGQVVAFDTEKPNLAIPRVINSELPPAIWAWAHAEVPYYFDARRSAVSRHYHYVM 115 >UniRef50_A0E7K0 Cluster: Pseudouridylate synthase; n=1; Paramecium tetraurelia|Rep: Pseudouridylate synthase - Paramecium tetraurelia Length = 351 Score = 47.6 bits (108), Expect = 3e-04 Identities = 39/150 (26%), Positives = 64/150 (42%), Gaps = 30/150 (20%) Frame = +2 Query: 278 RKKMAMLLGYSGVEYYGMQRNPGV--QTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSS 451 ++K+ + GY+G Y+G+Q GV +T+ I +++ + + + R + Sbjct: 7 KQKVLLTFGYNGANYHGLQIQKGVEFETVESKLFQALKDSNLIMEQNANDLSKSGWSRGA 66 Query: 452 RTDKGVSAAEQVVSLKL---------PLEVNVEE-------------------INKRLPE 547 RTDKGV A +++KL ++ N EE IN LP Sbjct: 67 RTDKGVHALCNSIAVKLCINKEFFKDEIQQNEEEIVSKLRDKQKVDYSKVLNVINSNLPN 126 Query: 548 TIKVFAVKRVTNRFNSKSKCNARSYSYTLP 637 IKV ++K VT F+ + R Y Y P Sbjct: 127 DIKVHSIKLVTQGFDVRKNARYRFYEYIAP 156 >UniRef50_Q8XLQ0 Cluster: tRNA pseudouridine synthase A 1; n=4; Clostridium|Rep: tRNA pseudouridine synthase A 1 - Clostridium perfringens Length = 248 Score = 47.6 bits (108), Expect = 3e-04 Identities = 33/123 (26%), Positives = 56/123 (45%), Gaps = 5/123 (4%) Frame = +2 Query: 281 KKMAMLLGYSGVEYYGMQR-NPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRT 457 + + + L Y G +Y G Q+ N + +T E+ Q RT Sbjct: 2 RNIKITLDYDGSKYKGWQKQNQKGSNVSTVQDKLEKVLTKMTSEEI------QLIGCGRT 55 Query: 458 DKGVSAAEQVVSLK----LPLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYS 625 D GV A V + K + LE +E IN+ LPE I+V ++ + RF+++ +++Y Sbjct: 56 DSGVHAKNYVANFKTNSLMTLEQIIEYINEYLPEDIRVTEIREASERFHARFNVKSKTYE 115 Query: 626 YTL 634 YT+ Sbjct: 116 YTI 118 >UniRef50_A2FDS7 Cluster: tRNA pseudouridine synthase family protein; n=1; Trichomonas vaginalis G3|Rep: tRNA pseudouridine synthase family protein - Trichomonas vaginalis G3 Length = 365 Score = 47.2 bits (107), Expect = 3e-04 Identities = 37/125 (29%), Positives = 61/125 (48%), Gaps = 8/125 (6%) Frame = +2 Query: 287 MAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTDKG 466 +A+ GY G Y+G + +T+ I+ + A ++ SSRTD G Sbjct: 40 IALCYGYLGTNYHGSSLHDQDKTVTLELQEALVNLGVISPNRTKGA--LKWSESSRTDTG 97 Query: 467 VSAAEQVVSLKL--PLEVNVEE----INKRLPET--IKVFAVKRVTNRFNSKSKCNARSY 622 V AA+QV + +L P V V++ I K+L + I+V+A + FN++ ++R Y Sbjct: 98 VHAAKQVATFRLVLPEGVKVKDLPRLIQKQLSKNSPIRVWAAVKPGIIFNAQQSASSRRY 157 Query: 623 SYTLP 637 Y LP Sbjct: 158 HYLLP 162 >UniRef50_Q64EQ0 Cluster: Pseudouridylate synthase; n=1; uncultured archaeon GZfos10C7|Rep: Pseudouridylate synthase - uncultured archaeon GZfos10C7 Length = 284 Score = 47.2 bits (107), Expect = 3e-04 Identities = 37/127 (29%), Positives = 59/127 (46%), Gaps = 4/127 (3%) Frame = +2 Query: 266 ERIKRKKMAMLLGYSGVEYYGMQRNP--GVQTIXXXXXXXXXXXXYITQEDFENAQNAQF 439 E +++++A+ +GY G Y+G Q P + TI I E+ + A + Sbjct: 3 EERQKERIALKIGYIGTNYHGFQIQPRSALPTIEGELFKALKKQGII-----EDRKTANY 57 Query: 440 QRSSRTDKGVSAAEQVVSLKLPLE-VNVEEINKRLPE-TIKVFAVKRVTNRFNSKSKCNA 613 + RTD GV A QVVS + IN LP+ +I V A+ + + FN++ + Sbjct: 58 SAAGRTDTGVHALAQVVSFVTSNQNTTPRMINSVLPDGSIWVSAIAKPYSGFNARRDAIS 117 Query: 614 RSYSYTL 634 R Y Y L Sbjct: 118 REYRYYL 124 >UniRef50_P70830 Cluster: tRNA pseudouridine synthase A; n=3; Borrelia burgdorferi group|Rep: tRNA pseudouridine synthase A - Borrelia burgdorferi (Lyme disease spirochete) Length = 246 Score = 47.2 bits (107), Expect = 3e-04 Identities = 30/123 (24%), Positives = 52/123 (42%), Gaps = 5/123 (4%) Frame = +2 Query: 281 KKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTD 460 KK+ + Y G Y+G Q P T+ N + + S RTD Sbjct: 2 KKILAEIAYDGSIYHGFQIQPTKPTVQGEIEKALMKI---------NKKKVKIHSSGRTD 52 Query: 461 KGVSAAEQVVSLKLPLEVNVEEINKR-----LPETIKVFAVKRVTNRFNSKSKCNARSYS 625 KGV A +Q+++ + + + + + K L +IK+ ++ V N F+ + R YS Sbjct: 53 KGVHAKKQIITFDIKINIQLNNLKKALNAILLKNSIKILKLRYVKNSFHPRFSAQKRKYS 112 Query: 626 YTL 634 Y + Sbjct: 113 YCI 115 >UniRef50_Q9UTB3 Cluster: Pseudouridylate synthase; n=1; Schizosaccharomyces pombe|Rep: Pseudouridylate synthase - Schizosaccharomyces pombe (Fission yeast) Length = 450 Score = 46.4 bits (105), Expect = 6e-04 Identities = 43/170 (25%), Positives = 72/170 (42%), Gaps = 9/170 (5%) Frame = +2 Query: 146 KDEENKSIDIVPNKLLTRYNKRRAHRDWETKPPGEIKKPYERIKRKKMAMLLGYSGVEYY 325 K++ + +I P L + A +D + P + +P++ K +A Y G Y Sbjct: 47 KNKLDNGNEIEPQHLSQELVLQHALQDASSLPKLKPVRPFQLEKTVFVAFKFAYCGWNYN 106 Query: 326 GM--QRNPG-VQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTDKGVSAAEQVVSL 496 G+ Q P + T+ IT + + F R RTDKGVSA QV+SL Sbjct: 107 GLAYQLEPTPLPTVEGKVFEALLRAHLIT-----DPSSCSFSRCGRTDKGVSAMGQVISL 161 Query: 497 KL------PLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYSY 628 + P+ + + +N+ LP I++ F+++ C R Y Y Sbjct: 162 NVRHSERRPI-IYCDVLNRLLPADIRITGYAFPPEGFDARFSCKQRHYKY 210 >UniRef50_Q4UIU5 Cluster: Pseudouridylate synthase; n=2; Theileria|Rep: Pseudouridylate synthase - Theileria annulata Length = 478 Score = 46.0 bits (104), Expect = 8e-04 Identities = 22/72 (30%), Positives = 38/72 (52%) Frame = +2 Query: 428 NAQFQRSSRTDKGVSAAEQVVSLKLPLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKC 607 +++ SS+ D + Q E V+ +N LPE I+ F ++RVT F+++S C Sbjct: 168 HSEINNSSKPDTSDNVELQSDGKLSKEEKFVQRLNAALPEDIRCFKIQRVTKGFDARSLC 227 Query: 608 NARSYSYTLPTY 643 + R Y Y +P + Sbjct: 228 SKRKYEYIIPEW 239 >UniRef50_Q6F1W2 Cluster: tRNA pseudouridine synthase A; n=3; Mollicutes|Rep: tRNA pseudouridine synthase A - Mesoplasma florum (Acholeplasma florum) Length = 251 Score = 46.0 bits (104), Expect = 8e-04 Identities = 39/123 (31%), Positives = 59/123 (47%), Gaps = 6/123 (4%) Frame = +2 Query: 284 KMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQR--SSRT 457 K + L Y G +++G P TI + + +NA F+ +S+T Sbjct: 3 KFLITLEYDGSDFHGWIEQPKTSTIQGE----------LNKAINRVTKNAVFKTIGASKT 52 Query: 458 DKGVSAAEQVVSLKL----PLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYS 625 D GV A +Q V L L L++ + INK LPETIKV +++ V FN + + YS Sbjct: 53 DTGVHAIDQKVLLDLGFNPKLDLFKKAINKALPETIKVRSIEEVKQDFNIRDVL-YKEYS 111 Query: 626 YTL 634 YT+ Sbjct: 112 YTI 114 >UniRef50_Q8KDR7 Cluster: tRNA pseudouridine synthase A; n=9; Chlorobiaceae|Rep: tRNA pseudouridine synthase A - Chlorobium tepidum Length = 247 Score = 46.0 bits (104), Expect = 8e-04 Identities = 34/123 (27%), Positives = 51/123 (41%), Gaps = 4/123 (3%) Frame = +2 Query: 278 RKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRT 457 ++ + M + Y G Y G QR PG + I QE + RT Sbjct: 5 KRTIKMQIEYDGTGYSGWQRQPG--DVVTVQGEIERVLERIMQEP------VSIDGAGRT 56 Query: 458 DKGVSAAEQVVSLK----LPLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYS 625 D GV A QV S +PL + N LP TI++ A+++ F+++ +R Y Sbjct: 57 DSGVHARRQVASFATCSPMPLGRLIYSANSLLPSTIRINAMRQAPESFHARFSATSREYR 116 Query: 626 YTL 634 Y L Sbjct: 117 YFL 119 >UniRef50_Q1FEL6 Cluster: Pseudouridylate synthase; n=1; Clostridium phytofermentans ISDg|Rep: Pseudouridylate synthase - Clostridium phytofermentans ISDg Length = 264 Score = 45.2 bits (102), Expect = 0.001 Identities = 34/131 (25%), Positives = 60/131 (45%), Gaps = 4/131 (3%) Frame = +2 Query: 260 PYERIKRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQF 439 P E +++ + +++ Y G Y G QR P + ++++ E + Sbjct: 2 PGEMDRKRNIKLIISYDGTNYSGWQRIP--KAANGDHSIQGLLEEFLSKVLLEPIK---L 56 Query: 440 QRSSRTDKGVSAAEQVVSL--KLPLEVNV--EEINKRLPETIKVFAVKRVTNRFNSKSKC 607 S RTD GV A QV + + L+VN+ +++N+ LPE IK+ V F+S+ Sbjct: 57 IGSGRTDTGVHALGQVANFYSRSNLDVNIIRQKMNQVLPEDIKILQANEVDLNFHSRFDA 116 Query: 608 NARSYSYTLPT 640 + Y Y + T Sbjct: 117 VEKIYQYIIDT 127 >UniRef50_A7HCM5 Cluster: tRNA-pseudouridine synthase I; n=2; Anaeromyxobacter|Rep: tRNA-pseudouridine synthase I - Anaeromyxobacter sp. Fw109-5 Length = 265 Score = 45.2 bits (102), Expect = 0.001 Identities = 34/123 (27%), Positives = 53/123 (43%), Gaps = 4/123 (3%) Frame = +2 Query: 272 IKRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSS 451 ++R+ A+ + Y G + G QR PG+ T+ A ++ Sbjct: 1 MERRFYALRVAYEGGRFRGFQRQPGLPTVQDALEGALLAAGV----------RATLAVAA 50 Query: 452 RTDKGVSAAEQVVSLKLPLEVNVEEI----NKRLPETIKVFAVKRVTNRFNSKSKCNARS 619 RTD GV A +QVVS ++ + N LPE + V V RV F++++ AR Sbjct: 51 RTDAGVHALDQVVSFSARAALDPAALRGALNAALPEGVAVLEVLRVAPSFHARNTARARR 110 Query: 620 YSY 628 Y Y Sbjct: 111 YVY 113 >UniRef50_A0LIV1 Cluster: Pseudouridylate synthase; n=1; Syntrophobacter fumaroxidans MPOB|Rep: Pseudouridylate synthase - Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB) Length = 261 Score = 45.2 bits (102), Expect = 0.001 Identities = 35/126 (27%), Positives = 53/126 (42%), Gaps = 4/126 (3%) Frame = +2 Query: 263 YERIKRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQ 442 Y+ +RK ++L Y G Y+G QR GV TI ++ + + Sbjct: 4 YDLPERKNFKLILEYDGSHYHGWQRQLGVLTIQEVLE---------SRLEVMLQSPVGVR 54 Query: 443 RSSRTDKGVSAAEQVVSLKLPLEVNVEE----INKRLPETIKVFAVKRVTNRFNSKSKCN 610 S RTD GV A QVV+ + + EE IN LP I V + F+++ Sbjct: 55 ASGRTDAGVHACGQVVNFHVHTRLRPEEILRGINSLLPPDIVVLHAEVAAESFHARFSAT 114 Query: 611 ARSYSY 628 ++Y Y Sbjct: 115 GKTYEY 120 >UniRef50_Q250I7 Cluster: Pseudouridylate synthase; n=2; Desulfitobacterium hafniense|Rep: Pseudouridylate synthase - Desulfitobacterium hafniense (strain Y51) Length = 271 Score = 44.4 bits (100), Expect = 0.002 Identities = 29/126 (23%), Positives = 52/126 (41%), Gaps = 4/126 (3%) Frame = +2 Query: 278 RKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRT 457 ++ + + + Y G Y+G QR P + +E N + RT Sbjct: 4 KRNICLKVAYDGTYYHGFQRQPEFHGPTIQGTLEAVWAKLVEEEVTLNT-------AGRT 56 Query: 458 DKGVSAAEQVVSLKLPLEVNVEEI----NKRLPETIKVFAVKRVTNRFNSKSKCNARSYS 625 D GV AA QVV+ + + V++I N LP I++ A + F+++ + Y Sbjct: 57 DTGVHAAGQVVNFRTGARIPVDKIPKAFNSLLPRDIRILAAQEAAENFHARFSAKWKRYD 116 Query: 626 YTLPTY 643 Y + + Sbjct: 117 YRIDNH 122 >UniRef50_Q0W2P8 Cluster: Pseudouridylate synthase; n=1; uncultured methanogenic archaeon RC-I|Rep: Pseudouridylate synthase - Uncultured methanogenic archaeon RC-I Length = 266 Score = 44.4 bits (100), Expect = 0.002 Identities = 32/119 (26%), Positives = 50/119 (42%), Gaps = 2/119 (1%) Frame = +2 Query: 284 KMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTDK 463 K A+ + Y G +YG Q PG+ T+ +E + + RTD Sbjct: 2 KTALKIAYVGTNFYGSQAQPGLPTVESELRK-------ALEEAGAIKLGTKIAMAGRTDA 54 Query: 464 GVSAAEQVVSLKL--PLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYSYTL 634 GV A QVV+ + P IN +LP+ + +A V + F+ + +R Y Y L Sbjct: 55 GVHALGQVVAFEQADPKLTAPRIINSKLPKDLWAYARAEVPDDFDPRRHATSREYRYIL 113 >UniRef50_Q8DWH1 Cluster: tRNA pseudouridine synthase A; n=42; Lactobacillales|Rep: tRNA pseudouridine synthase A - Streptococcus mutans Length = 249 Score = 44.4 bits (100), Expect = 0.002 Identities = 28/115 (24%), Positives = 56/115 (48%), Gaps = 4/115 (3%) Frame = +2 Query: 296 LLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTDKGVSA 475 ++ Y G + G QR P V+T+ T + Q + + RTD GV A Sbjct: 7 IISYDGTNFSGFQRQPQVRTVQEEIEK--------TLLRLNSGQAVKIHGAGRTDAGVHA 58 Query: 476 AEQVVSLKLPLEVNVEE----INKRLPETIKVFAVKRVTNRFNSKSKCNARSYSY 628 QV+ LP + ++E+ ++ + P+ I V V++V + F+++ + + ++Y + Sbjct: 59 YGQVIHFDLPQQRDLEKLRFGLDTQTPDDIDVIQVEQVADDFHARYQKHRKTYEF 113 >UniRef50_UPI00015B40A8 Cluster: PREDICTED: similar to pseudouridylate synthase; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to pseudouridylate synthase - Nasonia vitripennis Length = 421 Score = 43.6 bits (98), Expect = 0.004 Identities = 26/87 (29%), Positives = 42/87 (48%), Gaps = 13/87 (14%) Frame = +2 Query: 416 ENAQNAQFQRSSRTDKGVSAAEQVVSLKLPLEVNVEE-------------INKRLPETIK 556 E+ + + + R RTDKGVSA QV+SL + + E+ +N+ LP+ I+ Sbjct: 112 ESRETSNYHRCGRTDKGVSAFSQVISLDIRSRLEPEKQDNLSDELHYCKMLNRLLPKNIR 171 Query: 557 VFAVKRVTNRFNSKSKCNARSYSYTLP 637 F+ +++ C RSY Y P Sbjct: 172 CFSWSPAHPEMSARFDCKFRSYKYFFP 198 >UniRef50_A6DAN4 Cluster: Pseudouridylate synthase; n=1; Caminibacter mediatlanticus TB-2|Rep: Pseudouridylate synthase - Caminibacter mediatlanticus TB-2 Length = 223 Score = 43.6 bits (98), Expect = 0.004 Identities = 25/73 (34%), Positives = 36/73 (49%), Gaps = 4/73 (5%) Frame = +2 Query: 428 NAQFQRSSRTDKGVSAAEQVVSLKLP----LEVNVEEINKRLPETIKVFAVKRVTNRFNS 595 N+ Q + RTDKGV A QV+S +P L +NK + I + +K + N FN Sbjct: 24 NSIVQHAGRTDKGVHALNQVISFTIPNFWDLNKLQTSLNKIIHPYIHIKKIKFIKNDFNP 83 Query: 596 KSKCNARSYSYTL 634 + RSY Y + Sbjct: 84 RFNAKKRSYRYII 96 >UniRef50_Q7QV27 Cluster: GLP_180_17283_16483; n=1; Giardia lamblia ATCC 50803|Rep: GLP_180_17283_16483 - Giardia lamblia ATCC 50803 Length = 266 Score = 43.6 bits (98), Expect = 0.004 Identities = 29/87 (33%), Positives = 40/87 (45%), Gaps = 1/87 (1%) Frame = +2 Query: 236 KPPGEIKKPYERIKRKKMAMLLGYSGVEYYGMQRNPGVQ-TIXXXXXXXXXXXXYITQED 412 KP + I + +A+ + Y G EY G+ + P + TI I Q Sbjct: 76 KPSSRSLMDWSTIPLRHIAIQVCYDGTEYAGLAQQPNREYTIEELLLNALRGAALIPQH- 134 Query: 413 FENAQNAQFQRSSRTDKGVSAAEQVVS 493 A + F+RS RTD+GVSAA QV S Sbjct: 135 -AEASDVHFERSGRTDRGVSAAGQVFS 160 >UniRef50_O66953 Cluster: tRNA pseudouridine synthase A; n=1; Aquifex aeolicus|Rep: tRNA pseudouridine synthase A - Aquifex aeolicus Length = 241 Score = 43.6 bits (98), Expect = 0.004 Identities = 31/116 (26%), Positives = 52/116 (44%), Gaps = 4/116 (3%) Frame = +2 Query: 299 LGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTDKGVSAA 478 L + G +YG Q P ++T+ I ED + RTD GV A Sbjct: 8 LAFVGTNFYGWQVQPNLRTVQGEIQKALSQ---ILCED------VKVTGCCRTDSGVHAL 58 Query: 479 EQVVSLK----LPLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYSYTL 634 + + + K P E ++ +N LP+ + V+AVK+V+ FN++ + Y Y + Sbjct: 59 DYIANFKTQKDFPEEKLLKALNGILPKDVGVYAVKKVSEEFNARYSVKGKVYLYKI 114 >UniRef50_UPI0000E87E98 Cluster: tRNA pseudouridine synthase A; n=1; Methylophilales bacterium HTCC2181|Rep: tRNA pseudouridine synthase A - Methylophilales bacterium HTCC2181 Length = 264 Score = 42.7 bits (96), Expect = 0.007 Identities = 35/122 (28%), Positives = 55/122 (45%), Gaps = 5/122 (4%) Frame = +2 Query: 284 KMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSS-RTD 460 ++A + Y+G + G Q+ P V+TI I E A++ +S RTD Sbjct: 2 RIACSVSYNGYGFSGWQKQPDVKTIQGL----------IESALTEIAKDTVITHASGRTD 51 Query: 461 KGVSAAEQVVSLKL----PLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYSY 628 GV A Q++ PL V+ +N LP +IKV K ++ F+++ R Y Y Sbjct: 52 SGVHALGQIIHFDTTKNRPLTAWVKGVNAFLPSSIKVRWAKNISESFHARHSVLEREYQY 111 Query: 629 TL 634 L Sbjct: 112 LL 113 >UniRef50_Q1IRQ4 Cluster: Pseudouridylate synthase; n=2; Acidobacteria|Rep: Pseudouridylate synthase - Acidobacteria bacterium (strain Ellin345) Length = 257 Score = 42.7 bits (96), Expect = 0.007 Identities = 33/122 (27%), Positives = 50/122 (40%), Gaps = 4/122 (3%) Frame = +2 Query: 281 KKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTD 460 + + L Y G E++G Q PG TI T E Q Q S RTD Sbjct: 3 RNFKITLAYDGHEFHGWQIQPGKPTIQGTLAE--------TIERITGEQTLP-QGSGRTD 53 Query: 461 KGVSAAEQVVSLKLPLEVNVE----EINKRLPETIKVFAVKRVTNRFNSKSKCNARSYSY 628 GV A QV S+ L + + +N +LP +I+ V F+++ ++Y Y Sbjct: 54 AGVHALGQVASVALQTPIPADGLHIALNDKLPPSIRALTVGEAAPDFHARHSAKGKTYRY 113 Query: 629 TL 634 + Sbjct: 114 RI 115 >UniRef50_A0YB03 Cluster: Pseudouridylate synthase; n=10; Gammaproteobacteria|Rep: Pseudouridylate synthase - marine gamma proteobacterium HTCC2143 Length = 288 Score = 42.7 bits (96), Expect = 0.007 Identities = 36/123 (29%), Positives = 53/123 (43%), Gaps = 6/123 (4%) Frame = +2 Query: 284 KMAMLLGYSGVEYYGMQ--RNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRT 457 ++A+ + Y G Y+G Q R P V T+ NA N Q + RT Sbjct: 27 RVALCVSYDGSAYHGWQSQRKPQVATVQETLEKAL--------SSVANA-NVIVQCAGRT 77 Query: 458 DKGVSAAEQVVSLKLPL----EVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYS 625 D GV A+ Q+V P + V N LP +I + K V+ +FN++ AR Y Sbjct: 78 DTGVHASHQIVHFDSPSARGEKAWVRGGNTNLPSSIAIQWAKPVSAKFNARFSATARRYR 137 Query: 626 YTL 634 Y + Sbjct: 138 YVI 140 >UniRef50_Q4D8T5 Cluster: Pseudouridylate synthase I, putative; n=2; Trypanosoma cruzi|Rep: Pseudouridylate synthase I, putative - Trypanosoma cruzi Length = 655 Score = 42.7 bits (96), Expect = 0.007 Identities = 28/78 (35%), Positives = 38/78 (48%), Gaps = 9/78 (11%) Frame = +2 Query: 437 FQRSSRTDKGVSAAEQVVSLKLPLE--------VNVEE-INKRLPETIKVFAVKRVTNRF 589 F RS RTD+GV A +V L + E ++E +N LP TI+V V + F Sbjct: 79 FSRSCRTDRGVHAVRNLVCLFVFTERIEALGGCEKIKEMLNTTLPLTIRVARVTPLMGNF 138 Query: 590 NSKSKCNARSYSYTLPTY 643 + CN R Y Y +P Y Sbjct: 139 IPRFSCNRRVYHYLIPAY 156 >UniRef50_Q5L3Q7 Cluster: tRNA pseudouridine synthase A; n=11; Bacillaceae|Rep: tRNA pseudouridine synthase A - Geobacillus kaustophilus Length = 258 Score = 42.7 bits (96), Expect = 0.007 Identities = 30/124 (24%), Positives = 52/124 (41%), Gaps = 4/124 (3%) Frame = +2 Query: 281 KKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTD 460 +++ ++ Y G + G Q PG +T+ + S RTD Sbjct: 3 QRIKCIIAYDGTHFSGYQIQPGKRTVQGEFEEVLRR--------MHKGTKVRVAASGRTD 54 Query: 461 KGVSAAEQVVSLKLPLEVNVEE----INKRLPETIKVFAVKRVTNRFNSKSKCNARSYSY 628 GV A QV+ PL ++ E+ +N +LP+ I V V+ F+++ A+ Y Y Sbjct: 55 AGVHAYGQVIHFDTPLSLSSEQWKKALNAQLPDDIVVRFVQEADADFHARFSAKAKEYRY 114 Query: 629 TLPT 640 + T Sbjct: 115 KVWT 118 >UniRef50_A7PC02 Cluster: Chromosome chr2 scaffold_11, whole genome shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome chr2 scaffold_11, whole genome shotgun sequence - Vitis vinifera (Grape) Length = 370 Score = 42.3 bits (95), Expect = 0.010 Identities = 35/132 (26%), Positives = 57/132 (43%), Gaps = 9/132 (6%) Frame = +2 Query: 269 RIKRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQR- 445 R R ++L Y G + G Q+ PG+ T+ + +N + Sbjct: 91 RWARLTFKIVLSYHGASFDGWQKQPGLNTVQGLVEASLGRFVDERKAQQLKEKNLPVEGM 150 Query: 446 ---SSRTDKGVSAAEQVVSL---KLPLEV-NVEE-INKRLPETIKVFAVKRVTNRFNSKS 601 + RTDKGV+A +QV S K ++V ++E+ IN P ++V +V V+ F+ Sbjct: 151 VTVAGRTDKGVTALQQVCSFYTWKKDVKVQDIEDAINGAAPGKLRVISVSEVSRIFHPNF 210 Query: 602 KCNARSYSYTLP 637 R Y Y P Sbjct: 211 SAKWRHYFYIFP 222 >UniRef50_A5E2I9 Cluster: Pseudouridylate synthase; n=4; Saccharomycetales|Rep: Pseudouridylate synthase - Lodderomyces elongisporus (Yeast) (Saccharomyces elongisporus) Length = 491 Score = 42.3 bits (95), Expect = 0.010 Identities = 29/88 (32%), Positives = 41/88 (46%), Gaps = 17/88 (19%) Frame = +2 Query: 416 ENAQNAQFQRSSRTDKGVSAAEQVVSLKLPLEVNVEE----------------INKRLPE 547 E + ++ + RTDKGVSA QV+S+KL + +E IN LP Sbjct: 173 EPIEEVEYSKCGRTDKGVSAMNQVISIKLRSNLTPQEQQDPAFDAKEVDYFTVINANLPA 232 Query: 548 TIKVFAV-KRVTNRFNSKSKCNARSYSY 628 IKV A+ R F+++ C R Y Y Sbjct: 233 DIKVHAICLRPPENFDARFSCKERHYRY 260 >UniRef50_A7I4S8 Cluster: tRNA pseudouridine synthase A; n=1; Candidatus Methanoregula boonei 6A8|Rep: tRNA pseudouridine synthase A - Methanoregula boonei (strain 6A8) Length = 276 Score = 42.3 bits (95), Expect = 0.010 Identities = 28/116 (24%), Positives = 49/116 (42%), Gaps = 1/116 (0%) Frame = +2 Query: 284 KMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTDK 463 ++A + Y G +YG Q+ +T+ F + + A F + RTD+ Sbjct: 16 RLACRVSYLGTRFYGSQQQESSRTVEGEFIEACRRLAL-----FSDWRTAGFASAGRTDR 70 Query: 464 GVSAAEQVVSLKLPLEVNVEE-INKRLPETIKVFAVKRVTNRFNSKSKCNARSYSY 628 GV A QV++ + +N +LP I A V + F+ + +R+Y Y Sbjct: 71 GVHACGQVIAFSTQTPDRARQALNSQLPPDIWCTATAVVPDHFHPRYDARSRTYRY 126 >UniRef50_Q6DI24 Cluster: Zgc:56653 protein; n=2; Danio rerio|Rep: Zgc:56653 protein - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 386 Score = 41.9 bits (94), Expect = 0.013 Identities = 39/156 (25%), Positives = 69/156 (44%), Gaps = 27/156 (17%) Frame = +2 Query: 251 IKKPYE--RIKRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENA 424 ++KP++ R+ +A+ L Y G +Y G VQ + + ++ Sbjct: 46 VEKPFDFSAHPRRHVALRLAYLGWQYQGF----AVQENTDNTVEARLFEALLKTKLIQDR 101 Query: 425 QNAQFQRSSRTDKGVSAAEQVVSLKL-------------PLEVNVEE------------I 529 Q + + R RTDKGVSA QV+S+ L P +V+V+ + Sbjct: 102 QTSCYHRCGRTDKGVSAFSQVISIDLRSTQYGGGLGVTVPADVDVKGKTSADELPYVKIL 161 Query: 530 NKRLPETIKVFAVKRVTNRFNSKSKCNARSYSYTLP 637 N+ LP+ I++ V + F+++ C +R+Y Y P Sbjct: 162 NRVLPQDIRILQWAPVESGFSARFDCQSRTYRYYFP 197 >UniRef50_Q57WP9 Cluster: Pseudouridylate synthase I, putative; n=1; Trypanosoma brucei|Rep: Pseudouridylate synthase I, putative - Trypanosoma brucei Length = 618 Score = 41.9 bits (94), Expect = 0.013 Identities = 28/84 (33%), Positives = 40/84 (47%), Gaps = 9/84 (10%) Frame = +2 Query: 419 NAQNAQFQRSSRTDKGVSAAEQVVSLKLP---LEVN------VEEINKRLPETIKVFAVK 571 + + F RS RTD+GV A +V L +P LE + +N LP T++V V Sbjct: 73 SGEEHHFARSCRTDRGVHAVRNLVCLFVPNSKLEAAGGCDRLPQLLNAHLPSTVRVERVT 132 Query: 572 RVTNRFNSKSKCNARSYSYTLPTY 643 V F + C +R Y Y +P Y Sbjct: 133 TVMGDFIPRFCCVSRIYRYMIPVY 156 >UniRef50_Q6MDE3 Cluster: tRNA pseudouridine synthase A 2; n=1; Candidatus Protochlamydia amoebophila UWE25|Rep: tRNA pseudouridine synthase A 2 - Protochlamydia amoebophila (strain UWE25) Length = 262 Score = 41.9 bits (94), Expect = 0.013 Identities = 33/140 (23%), Positives = 58/140 (41%), Gaps = 5/140 (3%) Frame = +2 Query: 224 DWETKPPGEIKKPYERIKRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYIT 403 D+ T+ + K + IK K + Y G Y+G Q+ P ++ T Sbjct: 2 DYTTQSDLSLSKSMQNIKLK-----IAYDGQAYFGWQKTPAGPSVEKTLQNSLEQILQHT 56 Query: 404 QEDFENAQNAQFQRSSRTDKGVSAAEQVVSLK-----LPLEVNVEEINKRLPETIKVFAV 568 Q +SRTDKGV A Q+V+ L+ + +N LP +++ + Sbjct: 57 ---------ISLQAASRTDKGVHARGQIVNFLTTKSITDLQKFILSLNSLLPTDLRILSA 107 Query: 569 KRVTNRFNSKSKCNARSYSY 628 +++ + F+ C A+ Y Y Sbjct: 108 EKMPSTFHPTLNCVAKEYCY 127 >UniRef50_Q583N7 Cluster: Pseudouridylate synthase; n=1; Trypanosoma brucei|Rep: Pseudouridylate synthase - Trypanosoma brucei Length = 428 Score = 41.5 bits (93), Expect = 0.017 Identities = 40/148 (27%), Positives = 62/148 (41%), Gaps = 15/148 (10%) Frame = +2 Query: 230 ETKPPGEIKK-PYERIKRKKMAMLLGYSGVEYYGMQRNPGV-QTIXXXXXXXXXXXXYIT 403 E KP + ++ + +K+A+ L Y G Y G+ R T+ ++ Sbjct: 7 EGKPRSKERQFDFSSYPSRKIALRLAYHGHIYCGLVRQAETPNTVEAYLVAALERLRFV- 65 Query: 404 QEDFENAQNAQFQRSSRTDKGVSAAEQVVSL-------------KLPLEVNVEEINKRLP 544 E + F R RTDKGVSA VVS + PL+ E++N LP Sbjct: 66 ----EPSGPKDFSRCGRTDKGVSALGNVVSFTSRASSWATDEQQQPPLDY-CEKLNNVLP 120 Query: 545 ETIKVFAVKRVTNRFNSKSKCNARSYSY 628 TI++ V F+++ C R+Y Y Sbjct: 121 PTIRIVGWSYVNADFDARFSCTGRTYRY 148 >UniRef50_Q17C60 Cluster: Pseudouridylate synthase; n=2; Culicidae|Rep: Pseudouridylate synthase - Aedes aegypti (Yellowfever mosquito) Length = 467 Score = 41.5 bits (93), Expect = 0.017 Identities = 29/91 (31%), Positives = 46/91 (50%), Gaps = 17/91 (18%) Frame = +2 Query: 416 ENAQNAQFQRSSRTDKGVSAAEQVVSL---------------KLPLEVN-VEEINKRLPE 547 EN + + + R RTDKGVSA QVVSL + E+N + +N+ LP+ Sbjct: 115 ENRETSNYHRCGRTDKGVSAFHQVVSLDVRSKFAPENQLEPESIANEINYCQLLNRVLPQ 174 Query: 548 TIKVFA-VKRVTNRFNSKSKCNARSYSYTLP 637 I+ A + V ++++ C +R+Y Y P Sbjct: 175 DIRCVAWMPMVNPNYSARFDCRSRTYRYFFP 205 >UniRef50_Q7RDA0 Cluster: Putative uncharacterized protein PY05524; n=10; Plasmodium (Vinckeia)|Rep: Putative uncharacterized protein PY05524 - Plasmodium yoelii yoelii Length = 1510 Score = 41.1 bits (92), Expect = 0.022 Identities = 16/42 (38%), Positives = 25/42 (59%) Frame = +2 Query: 518 VEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYSYTLPTY 643 ++ +N LP IK F + +VT F+++ C+ R Y Y PTY Sbjct: 1219 IKLLNSNLPSDIKCFDIYKVTKSFDARKFCSFRLYEYLFPTY 1260 Score = 33.1 bits (72), Expect = 5.9 Identities = 30/121 (24%), Positives = 47/121 (38%), Gaps = 4/121 (3%) Frame = +2 Query: 185 KLLTRYNKRRAHRDWETKPPGEIKKPY----ERIKRKKMAMLLGYSGVEYYGMQRNPGVQ 352 KL NKRR D + + G+ K + K KK + +GY G Y+G Q G + Sbjct: 1032 KLKFERNKRRKEDDEKNEKGGDEKNEKGGDEKNNKFKKYGLCVGYIGSRYHGCQ-GQGKE 1090 Query: 353 TIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTDKGVSAAEQVVSLKLPLEVNVEEIN 532 + + N RS+RTD GV A + + +++ + N Sbjct: 1091 YMTIENEIERTLTKINAVKKTSKGFNYCLSRSARTDLGVHALYNLFVYNINIDICENDNN 1150 Query: 533 K 535 K Sbjct: 1151 K 1151 >UniRef50_Q6C194 Cluster: Pseudouridylate synthase; n=1; Yarrowia lipolytica|Rep: Pseudouridylate synthase - Yarrowia lipolytica (Candida lipolytica) Length = 443 Score = 41.1 bits (92), Expect = 0.022 Identities = 27/81 (33%), Positives = 43/81 (53%), Gaps = 17/81 (20%) Frame = +2 Query: 437 FQRSSRTDKGVSAAEQVVSLKLPLEVNVEE----------------INKRLPETIKVFAV 568 F R RTD+GVSA QV++LK+ +++ EE +N+ LP I++++V Sbjct: 137 FSRCGRTDRGVSAFSQVIALKVRSKLSPEEQQDAANDNKELNYIHILNQLLPPDIRIYSV 196 Query: 569 K-RVTNRFNSKSKCNARSYSY 628 R+ F+S+ C R Y Y Sbjct: 197 ALRLPEGFDSRFSCEYRHYRY 217 >UniRef50_Q2FT01 Cluster: Pseudouridylate synthase; n=1; Methanospirillum hungatei JF-1|Rep: Pseudouridylate synthase - Methanospirillum hungatei (strain JF-1 / DSM 864) Length = 276 Score = 41.1 bits (92), Expect = 0.022 Identities = 31/116 (26%), Positives = 51/116 (43%), Gaps = 1/116 (0%) Frame = +2 Query: 284 KMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTDK 463 ++A +GY G ++G Q P +T+ IT + Q ++ S RTD+ Sbjct: 12 RLAFRIGYIGTSFFGSQYQPDQRTVEGEIEAACLRAGIIT-----SRQVSRLALSGRTDR 66 Query: 464 GVSAAEQVVSLKL-PLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYSY 628 GV A Q+++L ++ V +N +LP I V A F + R+Y Y Sbjct: 67 GVHAKCQILALSTHNPDLAVRALNGQLPPDIWVSAWAYAPESFYPRYDVIIRTYRY 122 >UniRef50_Q9PPV4 Cluster: tRNA pseudouridine synthase A; n=1; Ureaplasma parvum|Rep: tRNA pseudouridine synthase A - Ureaplasma parvum (Ureaplasma urealyticum biotype 1) Length = 241 Score = 41.1 bits (92), Expect = 0.022 Identities = 32/120 (26%), Positives = 53/120 (44%), Gaps = 5/120 (4%) Frame = +2 Query: 299 LGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTDKGVSAA 478 L Y G +YG R P +T+ I + F+ N + S RTDKGV A Sbjct: 7 LRYDGSLFYGWARQPQKRTVQGDLEE-------IFKSIFK-INNIRIIGSGRTDKGVHAY 58 Query: 479 EQVVS-----LKLPLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYSYTLPTY 643 EQ S LK + + + R I++ V++V + F+++ +++Y Y + Y Sbjct: 59 EQTFSVKHSALKYDSHIIYQALCSRTSSDIQILEVQKVDDSFHAQYNATSKTYQYVINDY 118 >UniRef50_Q8TWZ3 Cluster: tRNA pseudouridine synthase A; n=1; Methanopyrus kandleri|Rep: tRNA pseudouridine synthase A - Methanopyrus kandleri Length = 256 Score = 41.1 bits (92), Expect = 0.022 Identities = 35/118 (29%), Positives = 52/118 (44%), Gaps = 1/118 (0%) Frame = +2 Query: 284 KMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTDK 463 ++A+ + Y G Y+G Q P V TI +++ E A SRTD Sbjct: 2 RVALRVAYDGSRYHGFQYQPDVPTIEGALRKA------LSELGLELVGYA-----SRTDA 50 Query: 464 GVSAAEQVVSLKLPLEV-NVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYSYTL 634 G A QVV ++ E+ + IN RLP+ I+V A V F+ + + Y Y L Sbjct: 51 GAHARYQVVVVEGDPELAQPDPINARLPKDIRVIAKTEVHEEFDPRRDALRKEYRYFL 108 >UniRef50_O28544 Cluster: tRNA pseudouridine synthase A; n=1; Archaeoglobus fulgidus|Rep: tRNA pseudouridine synthase A - Archaeoglobus fulgidus Length = 265 Score = 41.1 bits (92), Expect = 0.022 Identities = 29/117 (24%), Positives = 51/117 (43%) Frame = +2 Query: 284 KMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTDK 463 K A + Y G ++G Q P +T+ +N + + + RTD Sbjct: 3 KFAFKIAYFGDNFHGSQFQPDQRTVEGEVINALRRL---------GVENPRLRSAGRTDA 53 Query: 464 GVSAAEQVVSLKLPLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYSYTL 634 GV A QV+S ++ +N LPE I +A +V+ F+ + + +R Y+Y + Sbjct: 54 GVHAYGQVISFYSEDKIFPRMLNAELPEDITAWAWAKVSEDFDPR-RAKSRVYTYVM 109 >UniRef50_Q654A2 Cluster: Pseudouridylate synthase; n=3; Oryza sativa|Rep: Pseudouridylate synthase - Oryza sativa subsp. japonica (Rice) Length = 495 Score = 40.7 bits (91), Expect = 0.029 Identities = 33/132 (25%), Positives = 57/132 (43%), Gaps = 9/132 (6%) Frame = +2 Query: 269 RIKRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQR- 445 R +R ++L Y G + G Q+ PG+ T+ + A++ + Sbjct: 117 RWERVTFKIVLSYHGGSFDGWQKQPGLNTVQGLVEKHLGQFVDEKKAKQLEARSLPLEGC 176 Query: 446 ---SSRTDKGVSAAEQVVSL----KLPLEVNVEE-INKRLPETIKVFAVKRVTNRFNSKS 601 + RTDKGV+A +QV S K ++++ INK P+ ++ V +V+ F+ Sbjct: 177 AVVAGRTDKGVTALQQVCSFYTWRKDVKSSDIKDAINKAAPDKLRPLHVSQVSREFHPNF 236 Query: 602 KCNARSYSYTLP 637 R Y Y P Sbjct: 237 AAKWRRYLYIFP 248 >UniRef50_Q5CPW7 Cluster: Pus1p-like type II pseudousynthas TruA; n=2; Cryptosporidium|Rep: Pus1p-like type II pseudousynthas TruA - Cryptosporidium parvum Iowa II Length = 501 Score = 40.7 bits (91), Expect = 0.029 Identities = 19/49 (38%), Positives = 31/49 (63%), Gaps = 1/49 (2%) Frame = +2 Query: 500 LPLEVNVEEINKRLPET-IKVFAVKRVTNRFNSKSKCNARSYSYTLPTY 643 L L+ V ++N+ L T IKVF + RVT F++++ C+ R Y Y +P + Sbjct: 163 LILDYIVTKLNELLESTKIKVFKIFRVTKNFDARTDCSRRQYEYLMPEF 211 Score = 35.5 bits (78), Expect = 1.1 Identities = 29/99 (29%), Positives = 41/99 (41%), Gaps = 13/99 (13%) Frame = +2 Query: 266 ERIKRKKMAMLLGYSGVEYYGMQ----RNPGVQTIXXXXXXXXXXXXYITQEDFENAQN- 430 E I K M GY G +Y+GMQ N V+ + + N QN Sbjct: 3 EVIPMKTYCMSFGYDGSDYHGMQIQMRNNKKVEELRTIEGEMEDCLEKLGMFFLSNEQND 62 Query: 431 --------AQFQRSSRTDKGVSAAEQVVSLKLPLEVNVE 523 ++ R RTDKGV + QVVS + +++N E Sbjct: 63 DQGGLLKKIKWSRVGRTDKGVHSVCQVVSFRAKIKINDE 101 >UniRef50_A3LX03 Cluster: Pseudouridylate synthase; n=4; Saccharomycetaceae|Rep: Pseudouridylate synthase - Pichia stipitis (Yeast) Length = 465 Score = 40.7 bits (91), Expect = 0.029 Identities = 40/140 (28%), Positives = 60/140 (42%), Gaps = 20/140 (14%) Frame = +2 Query: 269 RIKRKKMAMLLGYSGVEYYGM--QRNPG-VQTIXXXXXXXXXXXXYITQEDFENAQNAQF 439 + ++ +A+ Y G Y G+ Q P + T+ IT+ +F Sbjct: 85 KYNKRFIALKFAYLGWNYNGLAYQSEPTPLPTVEEVVLKALTMSRLITEP---TPDKCKF 141 Query: 440 QRSSRTDKGVSAAEQVVSLKLPLEVNVEE----------------INKRLPETIKVFAV- 568 R RTDKGVSA QV+SL + +N EE IN LP I++ AV Sbjct: 142 SRCGRTDKGVSAMNQVISLVVRSNLNEEEQLLKENDHKEIKYLSIINALLPPDIRMTAVC 201 Query: 569 KRVTNRFNSKSKCNARSYSY 628 R +F+++ C+ R Y Y Sbjct: 202 LRPPPKFDARFSCDYRHYRY 221 >UniRef50_A0B7V0 Cluster: Pseudouridylate synthase; n=1; Methanosaeta thermophila PT|Rep: Pseudouridylate synthase - Methanosaeta thermophila (strain DSM 6194 / PT) (Methanothrixthermophila (strain DSM 6194 / PT)) Length = 267 Score = 40.7 bits (91), Expect = 0.029 Identities = 33/121 (27%), Positives = 49/121 (40%), Gaps = 4/121 (3%) Frame = +2 Query: 284 KMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTDK 463 K+A+ + Y G YYG QR PG++T+ N F + RTD+ Sbjct: 2 KIALKIAYLGDRYYGFQRQPGLRTVESVMRDALLRI---------GVANGDFCYAGRTDR 52 Query: 464 GVSAAEQVVSLKLPLE----VNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYSYT 631 GVSA QV+ + + IN LP + +A F+++ R Y Y Sbjct: 53 GVSALGQVIDFWIEEDRAYLAFPRVINSLLPSDVWAWARAVAPVGFSARWSALWREYRYF 112 Query: 632 L 634 L Sbjct: 113 L 113 >UniRef50_Q057U4 Cluster: Pseudouridylate synthase; n=1; Buchnera aphidicola str. Cc (Cinara cedri)|Rep: Pseudouridylate synthase - Buchnera aphidicola subsp. Cinara cedri Length = 269 Score = 40.3 bits (90), Expect = 0.039 Identities = 23/67 (34%), Positives = 37/67 (55%), Gaps = 4/67 (5%) Frame = +2 Query: 446 SSRTDKGVSAAEQVVSLKLPLEVNVEE----INKRLPETIKVFAVKRVTNRFNSKSKCNA 613 + RTDKGV A Q+V + N E +N LP+ I V +K+V++ F+++ + Sbjct: 47 AGRTDKGVHAITQIVHFSSLIIRNEEVWFTGLNSLLPKNITVLWLKKVSSNFHARFSALS 106 Query: 614 RSYSYTL 634 RSY Y + Sbjct: 107 RSYRYII 113 >UniRef50_Q09524 Cluster: Probable tRNA pseudouridine synthase tag-124; n=2; Caenorhabditis|Rep: Probable tRNA pseudouridine synthase tag-124 - Caenorhabditis elegans Length = 402 Score = 40.3 bits (90), Expect = 0.039 Identities = 43/146 (29%), Positives = 62/146 (42%), Gaps = 28/146 (19%) Frame = +2 Query: 278 RKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRT 457 R+K+A+ Y G E+ G+ + P Q ++ E+ F R RT Sbjct: 29 RRKIAIQFFYLGWEHDGLVQQPHTQNTVENHIMQALIKTHL----IEDWTKCDFSRCGRT 84 Query: 458 DKGVS-----AAEQVVSL-----------------KLPLEVNVEEI------NKRLPETI 553 DKGVS AA V SL K+ + + EE+ N LP+TI Sbjct: 85 DKGVSAFKQTAAMVVRSLCPGDSGVFWSDSTQEHQKVDYKASGEELPYVKMLNGVLPKTI 144 Query: 554 KVFAVKRVTNRFNSKSKCNARSYSYT 631 +VFA V FN++ CN R+Y Y+ Sbjct: 145 RVFAWAPVAQTFNARFDCNRRTYKYS 170 >UniRef50_A4XKB7 Cluster: Pseudouridylate synthase; n=3; Clostridiales|Rep: Pseudouridylate synthase - Caldicellulosiruptor saccharolyticus (strain ATCC 43494 / DSM 8903) Length = 244 Score = 39.9 bits (89), Expect = 0.051 Identities = 29/122 (23%), Positives = 51/122 (41%), Gaps = 4/122 (3%) Frame = +2 Query: 281 KKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTD 460 + + + + Y G Y+G Q+ P +T+ IT ED S RTD Sbjct: 2 RNILLTIEYDGTNYFGWQKQPNKKTVQGVIEDAIKK---ITGED------VNLVGSGRTD 52 Query: 461 KGVSAAEQVVSLKLPLEVNVEE----INKRLPETIKVFAVKRVTNRFNSKSKCNARSYSY 628 +GV A Q + K ++ E+ +N LP I + V+ F+++ ++Y Y Sbjct: 53 RGVHALGQKANFKTESKIPTEKFPLALNSVLPNDISIKDAAEVSLDFSARYSAKQKTYKY 112 Query: 629 TL 634 + Sbjct: 113 LI 114 >UniRef50_Q8CWM6 Cluster: tRNA pseudouridine synthase A; n=1; Synechococcus elongatus|Rep: tRNA pseudouridine synthase A - Synechococcus elongatus (Thermosynechococcus elongatus) Length = 284 Score = 39.9 bits (89), Expect = 0.051 Identities = 34/126 (26%), Positives = 59/126 (46%), Gaps = 6/126 (4%) Frame = +2 Query: 281 KKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQN--AQFQRSSR 454 +++A+L+ Y G ++G QR G +T+ + ++ + N + R Sbjct: 12 QRLALLIQYQGTHFHGWQRQVGQRTVQE-----------VIEQAIASVVNHPVSVVAAGR 60 Query: 455 TDKGVSAAEQV--VSLKLPLEVNVEE--INKRLPETIKVFAVKRVTNRFNSKSKCNARSY 622 TD GV AA QV V++ P+ V+ +N RLP + + A V ++++ R Y Sbjct: 61 TDTGVHAAGQVAHVTVNSPIPVHRWPGILNARLPADVVIRAAAAVPPDWHARFSALWRRY 120 Query: 623 SYTLPT 640 YTL T Sbjct: 121 RYTLYT 126 >UniRef50_P31115 Cluster: tRNA pseudouridine synthase 3; n=5; Saccharomycetales|Rep: tRNA pseudouridine synthase 3 - Saccharomyces cerevisiae (Baker's yeast) Length = 442 Score = 39.9 bits (89), Expect = 0.051 Identities = 29/85 (34%), Positives = 43/85 (50%), Gaps = 17/85 (20%) Frame = +2 Query: 425 QNAQFQRSSRTDKGVSAAEQVVSLKLPLEVNVEE----------------INKRLPETIK 556 Q+ +F R RTDKGVSA QV+SL++ + EE +N+ LP+ I+ Sbjct: 140 QDYKFSRCGRTDKGVSAMNQVISLEVRSNLTDEEQRDPTNDSREIPYVHVLNQLLPDDIR 199 Query: 557 VFAV-KRVTNRFNSKSKCNARSYSY 628 + AV R F+++ C R Y Y Sbjct: 200 ISAVCLRPPPNFDARFSCVHRHYKY 224 >UniRef50_Q820P8 Cluster: tRNA pseudouridine synthase A; n=10; Proteobacteria|Rep: tRNA pseudouridine synthase A - Nitrosomonas europaea Length = 272 Score = 39.5 bits (88), Expect = 0.067 Identities = 32/121 (26%), Positives = 48/121 (39%), Gaps = 4/121 (3%) Frame = +2 Query: 284 KMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTDK 463 K+ + L Y G Y G Q+ PG ++ + Q + RTD Sbjct: 13 KIVLALEYDGRGYCGWQKQPGCLSVQSRLESALSGVA---------GRQIQVVAAGRTDA 63 Query: 464 GVSAAEQVVSL----KLPLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYSYT 631 GV A QVV L + PL + N LP I + V++ F+++ R+Y Y Sbjct: 64 GVHALCQVVHLETCVRRPLNAWIRGTNALLPGDISILEASEVSDDFHARFSATERTYLYY 123 Query: 632 L 634 L Sbjct: 124 L 124 >UniRef50_Q88XU9 Cluster: tRNA pseudouridine synthase A; n=10; Lactobacillales|Rep: tRNA pseudouridine synthase A - Lactobacillus plantarum Length = 262 Score = 39.5 bits (88), Expect = 0.067 Identities = 31/116 (26%), Positives = 48/116 (41%), Gaps = 4/116 (3%) Frame = +2 Query: 293 MLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTDKGVS 472 ++L Y G + G QR P +T+ + + + + + RTD GV Sbjct: 7 VVLAYDGTNFAGFQRQPHQRTVEQVVTKA------VNKMAKDPVEPIVIYGAGRTDAGVH 60 Query: 473 AAEQVVSLKLPLEVNVEEI----NKRLPETIKVFAVKRVTNRFNSKSKCNARSYSY 628 A Q + LP E+N E + N LP V AV V N F+++ + Y Y Sbjct: 61 AFGQTLHFDLPYEINPEGVRRGLNSMLPMDTIVKAVSIVPNDFHARYDTVGKRYWY 116 >UniRef50_Q3ZZP4 Cluster: Pseudouridylate synthase; n=3; Dehalococcoides|Rep: Pseudouridylate synthase - Dehalococcoides sp. (strain CBDB1) Length = 246 Score = 39.1 bits (87), Expect = 0.089 Identities = 26/73 (35%), Positives = 36/73 (49%), Gaps = 4/73 (5%) Frame = +2 Query: 422 AQNAQFQRSSRTDKGVSAAEQVVSLKLPLEVNVEEI----NKRLPETIKVFAVKRVTNRF 589 ++ + S RTD GV AA QVVS + +E+I N LP I V V V F Sbjct: 35 SEQTRVSGSGRTDAGVHAAYQVVSYLTESSLGLEKIKGGLNYYLPPDIAVKEVHFVAENF 94 Query: 590 NSKSKCNARSYSY 628 + + + +R YSY Sbjct: 95 DVRRRAISREYSY 107 >UniRef50_Q3Y386 Cluster: Pseudouridylate synthase; n=3; Firmicutes|Rep: Pseudouridylate synthase - Enterococcus faecium DO Length = 246 Score = 39.1 bits (87), Expect = 0.089 Identities = 21/65 (32%), Positives = 33/65 (50%), Gaps = 4/65 (6%) Frame = +2 Query: 446 SSRTDKGVSAAEQVVSLKLPLEVNVEEI----NKRLPETIKVFAVKRVTNRFNSKSKCNA 613 S RTD G A QV + K E+ + E+ N+ LP I + ++ + RF+S+ Sbjct: 49 SGRTDAGTHARGQVANFKTNTEIGLAEMIDFMNRYLPRDIVIKRIEEMPERFHSRYNAVG 108 Query: 614 RSYSY 628 + YSY Sbjct: 109 KKYSY 113 >UniRef50_Q8GUL5 Cluster: Putative uncharacterized protein At5g35400; n=1; Arabidopsis thaliana|Rep: Putative uncharacterized protein At5g35400 - Arabidopsis thaliana (Mouse-ear cress) Length = 420 Score = 39.1 bits (87), Expect = 0.089 Identities = 32/132 (24%), Positives = 56/132 (42%), Gaps = 9/132 (6%) Frame = +2 Query: 269 RIKRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQR- 445 R +R ++L Y+G + G Q+ P + T+ + + + Sbjct: 89 RWERVNFKIVLSYNGASFDGWQKQPDLHTVQGVVEKSLGGFVDERKAQLLKKKCKPLEGR 148 Query: 446 ---SSRTDKGVSAAEQVVSL---KLPLE-VNVEE-INKRLPETIKVFAVKRVTNRFNSKS 601 + RTDKGVSA QV S + +E + +E+ INK ++V ++ +V+ F+ Sbjct: 149 VLVAGRTDKGVSALNQVCSFYTWRKDIEPIAIEDAINKDASGKLRVVSISKVSRSFHPNF 208 Query: 602 KCNARSYSYTLP 637 R Y Y P Sbjct: 209 SAKWRRYLYIFP 220 >UniRef50_Q8I0W4 Cluster: TRNA pseudouridine synthase, putative; n=6; Plasmodium|Rep: TRNA pseudouridine synthase, putative - Plasmodium falciparum (isolate 3D7) Length = 304 Score = 39.1 bits (87), Expect = 0.089 Identities = 25/73 (34%), Positives = 41/73 (56%), Gaps = 11/73 (15%) Frame = +2 Query: 443 RSSRTDKGVSAAEQVVSLKLPLEVN-----------VEEINKRLPETIKVFAVKRVTNRF 589 R SRTDKGVSA ++L+L ++ V+E+ K+L + I + +K V+N F Sbjct: 46 RVSRTDKGVSARINGINLRLNIKYENVPIFEIEKKYVKELKKKL-KNIHIHDIKHVSNTF 104 Query: 590 NSKSKCNARSYSY 628 +++ C R+Y Y Sbjct: 105 DARLNCIQRTYVY 117 >UniRef50_Q22RZ3 Cluster: TRNA pseudouridine synthase family protein; n=1; Tetrahymena thermophila SB210|Rep: TRNA pseudouridine synthase family protein - Tetrahymena thermophila SB210 Length = 484 Score = 39.1 bits (87), Expect = 0.089 Identities = 23/77 (29%), Positives = 39/77 (50%), Gaps = 2/77 (2%) Frame = +2 Query: 284 KMAMLLGYSGVEYYGMQ--RNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRT 457 K+A+ GY+G Y+G Q ++ ++TI I++ + A + R +RT Sbjct: 12 KVAIFFGYNGKGYHGSQSQKDQNIKTIEKSLFEGLIDSKLISETHMGELKKAGWGRGART 71 Query: 458 DKGVSAAEQVVSLKLPL 508 DKGV A V++KL + Sbjct: 72 DKGVHALCNGVNVKLAI 88 >UniRef50_A3CXX4 Cluster: Pseudouridylate synthase; n=1; Methanoculleus marisnigri JR1|Rep: Pseudouridylate synthase - Methanoculleus marisnigri (strain ATCC 35101 / DSM 1498 / JR1) Length = 270 Score = 39.1 bits (87), Expect = 0.089 Identities = 30/115 (26%), Positives = 48/115 (41%), Gaps = 1/115 (0%) Frame = +2 Query: 287 MAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTDKG 466 +A Y G ++G Q P + T+ F++ + A F + RTD+G Sbjct: 3 LAFRFSYFGDRFFGSQMQPDLCTVEGEFIGACRLLRL-----FDDWREANFATAGRTDRG 57 Query: 467 VSAAEQVVS-LKLPLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYSY 628 V A QV S L E +E +N+ LP I + F+ + +R+Y Y Sbjct: 58 VHARSQVCSFLTDKPERAIEALNRVLPADIWCTGWAEAPDGFHPRYSAVSRTYRY 112 >UniRef50_Q9X1R0 Cluster: tRNA pseudouridine synthase A; n=5; Thermotogaceae|Rep: tRNA pseudouridine synthase A - Thermotoga maritima Length = 245 Score = 39.1 bits (87), Expect = 0.089 Identities = 33/125 (26%), Positives = 55/125 (44%), Gaps = 5/125 (4%) Frame = +2 Query: 281 KKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTD 460 K++A ++ Y G ++G Q P V+T+ + F+ Q Q + RTD Sbjct: 2 KRVAAVIEYDGSNFFGYQGQPDVRTVQGVIEDAL-------ERIFK--QRIYTQAAGRTD 52 Query: 461 KGVSAAEQVVSLKLPLE-VNVEEI----NKRLPETIKVFAVKRVTNRFNSKSKCNARSYS 625 GV A Q+++ P + + E+I N LP+ + V V V F+ + R Y Sbjct: 53 TGVHANGQLIAFNCPNDRMTTEDIRNAMNANLPDDVYVKEVFEVPVNFHPRFDVTKRIYH 112 Query: 626 YTLPT 640 Y + T Sbjct: 113 YFILT 117 >UniRef50_UPI00015653AF Cluster: tRNA-pseudouridine synthase A; n=1; Symbiobacterium thermophilum IAM 14863|Rep: tRNA-pseudouridine synthase A - Symbiobacterium thermophilum IAM 14863 Length = 267 Score = 38.7 bits (86), Expect = 0.12 Identities = 33/121 (27%), Positives = 50/121 (41%), Gaps = 4/121 (3%) Frame = +2 Query: 281 KKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTD 460 + + ++L Y G Y G QR P TI +T E A + RTD Sbjct: 2 RTIKLILAYDGTAYAGFQRQPNGITIQQRLEEALRA---VTGEPDLRIGAA----AGRTD 54 Query: 461 KGVSAAEQVVSLK----LPLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYSY 628 GV A QVV L+ +P++ +N LP+ I V + F+++ + Y Y Sbjct: 55 AGVHARGQVVHLRTYATIPIDRWPAALNGHLPDDIAVIGAEEAPPDFHARYWAREKRYRY 114 Query: 629 T 631 T Sbjct: 115 T 115 >UniRef50_UPI000049A0B0 Cluster: pseudouridine synthase; n=1; Entamoeba histolytica HM-1:IMSS|Rep: pseudouridine synthase - Entamoeba histolytica HM-1:IMSS Length = 366 Score = 38.7 bits (86), Expect = 0.12 Identities = 38/145 (26%), Positives = 59/145 (40%), Gaps = 23/145 (15%) Frame = +2 Query: 263 YERIKRKKMAMLLGYSGVEYYGMQ---RNPGVQTIXXXXXXXXXXXXYITQEDF-----E 418 + K + +A+ L Y G++Y G+Q N + + F + Sbjct: 30 FNNYKTRHIAIRLTYIGIDYNGIQCTLLNDVTDATFDSVINDGTIEYQLFKALFKTRLIQ 89 Query: 419 NAQNAQFQRSSRTDKGVSAAEQVVSLKLPLEVNVEEI---------------NKRLPETI 553 N ++ ++ R RTDKGVSA QVV L + + E I N LP I Sbjct: 90 NTKDCKYNRCGRTDKGVSAFGQVVDLWVRSNLKDETILYTKREGELDYCRMLNGLLPTDI 149 Query: 554 KVFAVKRVTNRFNSKSKCNARSYSY 628 + V + FNS+ C +R+Y Y Sbjct: 150 RCLGWCGVPDDFNSRFSCQSRTYHY 174 >UniRef50_Q8IAP2 Cluster: Putative uncharacterized protein PF08_0123; n=1; Plasmodium falciparum 3D7|Rep: Putative uncharacterized protein PF08_0123 - Plasmodium falciparum (isolate 3D7) Length = 530 Score = 38.7 bits (86), Expect = 0.12 Identities = 30/99 (30%), Positives = 44/99 (44%), Gaps = 6/99 (6%) Frame = +2 Query: 197 RYNKRRAHRDWETKPPGEIKKPYERIKR-----KKMAMLLGYSGVEYYGMQ-RNPGVQTI 358 R K + R K E K+ YE ++ KK A+ +GY G +Y+G Q + +TI Sbjct: 18 RIKKLKLERQAIKKKEEEGKEKYENEEKNNLNLKKYALCIGYIGSQYHGCQGQGENCETI 77 Query: 359 XXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTDKGVSA 475 I ++ F N RS+RTD+GV A Sbjct: 78 ENTLERTLLKINAIKKKKFFKNFNFCLSRSARTDQGVHA 116 Score = 37.1 bits (82), Expect = 0.36 Identities = 15/39 (38%), Positives = 22/39 (56%) Frame = +2 Query: 527 INKRLPETIKVFAVKRVTNRFNSKSKCNARSYSYTLPTY 643 +N LP IK F + +VT F+++ C+ R Y Y P Y Sbjct: 223 LNDHLPCDIKCFKIYKVTKSFDARKFCSFRFYEYLFPVY 261 >UniRef50_Q4Q7E9 Cluster: Pseudouridylate synthase; n=5; Trypanosomatidae|Rep: Pseudouridylate synthase - Leishmania major Length = 498 Score = 38.7 bits (86), Expect = 0.12 Identities = 34/134 (25%), Positives = 53/134 (39%), Gaps = 12/134 (8%) Frame = +2 Query: 263 YERIKRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQ 442 ++R +K+A+ L Y G + G+ + + ED + F Sbjct: 54 FDRYPSRKIALRLAYHGHVHDGLAKQKETDNTVEGLVCDALRRLRLIPEDGPH----NFG 109 Query: 443 RSSRTDKGVSAAEQVVSL------------KLPLEVNVEEINKRLPETIKVFAVKRVTNR 586 R RTDKGVSA SL +LP +N LP TI++ V + Sbjct: 110 RCGRTDKGVSALGNAFSLTARASCTGDAEPQLPPLDYCSMLNNVLPSTIRIVGCALVDDA 169 Query: 587 FNSKSKCNARSYSY 628 F+++ C R+Y Y Sbjct: 170 FDARFSCVHRTYRY 183 >UniRef50_Q64XV0 Cluster: tRNA pseudouridine synthase A; n=16; Bacteroidetes|Rep: tRNA pseudouridine synthase A - Bacteroides fragilis Length = 252 Score = 38.7 bits (86), Expect = 0.12 Identities = 24/70 (34%), Positives = 38/70 (54%), Gaps = 5/70 (7%) Frame = +2 Query: 446 SSRTDKGVSAAEQVVSLKL---PLEVN--VEEINKRLPETIKVFAVKRVTNRFNSKSKCN 610 + RTD GV A+ V PL+V+ E++N+ LP+ I V+ V RV +++ Sbjct: 50 AGRTDAGVHASLMVAHFDYEGEPLDVDKVAEKLNRLLPQDISVYKVCRVKPDAHARFDAT 109 Query: 611 ARSYSYTLPT 640 AR+Y Y + T Sbjct: 110 ARTYKYYITT 119 >UniRef50_Q3A9U9 Cluster: Pseudouridylate synthase; n=1; Carboxydothermus hydrogenoformans Z-2901|Rep: Pseudouridylate synthase - Carboxydothermus hydrogenoformans (strain Z-2901 / DSM 6008) Length = 246 Score = 38.3 bits (85), Expect = 0.16 Identities = 22/67 (32%), Positives = 34/67 (50%), Gaps = 4/67 (5%) Frame = +2 Query: 446 SSRTDKGVSAAEQVVSLKLPLEVNVEEI----NKRLPETIKVFAVKRVTNRFNSKSKCNA 613 + RTD GV A QVV+ P + V++I N LP I+V + V + F+++ Sbjct: 52 AGRTDAGVHALGQVVNFSAPWKAPVDKIPEILNNTLPTAIRVLEAEIVPDDFHARYSARK 111 Query: 614 RSYSYTL 634 + Y Y L Sbjct: 112 KEYRYYL 118 >UniRef50_Q08Z59 Cluster: Pseudouridylate synthase; n=2; Cystobacterineae|Rep: Pseudouridylate synthase - Stigmatella aurantiaca DW4/3-1 Length = 303 Score = 38.3 bits (85), Expect = 0.16 Identities = 34/123 (27%), Positives = 50/123 (40%), Gaps = 4/123 (3%) Frame = +2 Query: 272 IKRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSS 451 +KR + L Y G ++G QR P T+ A + Sbjct: 24 LKRLSTTLWLWYRGGGFHGFQRQPEGPTVQSTLEAVLR----------STGVPATVMPAG 73 Query: 452 RTDKGVSAAEQVVSLKLPLEVNVEEINKRLPETIK----VFAVKRVTNRFNSKSKCNARS 619 RTD+GV A QVVSL+L E + RLP + V AV+R F+++ ++ Sbjct: 74 RTDRGVHARMQVVSLRLEAGDTPEALAARLPALLPPDLGVCAVRRPPPSFHAQWSAAGKT 133 Query: 620 YSY 628 Y Y Sbjct: 134 YCY 136 >UniRef50_Q7MBB9 Cluster: tRNA pseudouridine synthase A; n=1; Gloeobacter violaceus|Rep: tRNA pseudouridine synthase A - Gloeobacter violaceus Length = 304 Score = 38.3 bits (85), Expect = 0.16 Identities = 32/121 (26%), Positives = 55/121 (45%), Gaps = 4/121 (3%) Frame = +2 Query: 284 KMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTDK 463 ++A+ + Y G ++G Q PG +T+ T+ + ++ + RTD Sbjct: 16 RLALRVQYLGGHFFGWQWQPGQRTVQQCLEEA-------TERIARHP--VRYHAAGRTDT 66 Query: 464 GVSAAEQVVSL----KLPLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYSYT 631 GV A+ QVV KL E V +N LP+ I V A V++ ++++ R Y Y Sbjct: 67 GVHASGQVVHFDTHKKLAPETWVRGLNSLLPDDIAVRAAAYVSDHWHARFTALWREYRYC 126 Query: 632 L 634 + Sbjct: 127 I 127 >UniRef50_Q9BZE2 Cluster: tRNA pseudouridine synthase 3; n=19; Euteleostomi|Rep: tRNA pseudouridine synthase 3 - Homo sapiens (Human) Length = 481 Score = 38.3 bits (85), Expect = 0.16 Identities = 31/97 (31%), Positives = 45/97 (46%), Gaps = 23/97 (23%) Frame = +2 Query: 416 ENAQNAQFQRSSRTDKGVSAAEQVVSLKL---------PLEVNVEE-------------- 526 E+ Q + + R RTDKGVSA QV+SL L + NV+E Sbjct: 104 ESRQTSNYHRCGRTDKGVSAFGQVISLDLRSQFPRGRDSEDFNVKEEANAAAEEIRYTHI 163 Query: 527 INKRLPETIKVFAVKRVTNRFNSKSKCNARSYSYTLP 637 +N+ LP I++ A V F+++ C R+Y Y P Sbjct: 164 LNRVLPPDIRILAWAPVEPSFSARFSCLERTYRYFFP 200 >UniRef50_A6Q408 Cluster: Pseudouridylate synthase; n=2; unclassified Epsilonproteobacteria|Rep: Pseudouridylate synthase - Nitratiruptor sp. (strain SB155-2) Length = 241 Score = 37.9 bits (84), Expect = 0.21 Identities = 24/68 (35%), Positives = 34/68 (50%), Gaps = 5/68 (7%) Frame = +2 Query: 446 SSRTDKGVSAAEQVVSLKLP-----LEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCN 610 S RTDKGV A QV+ LP LE +N+ L I++ V +V F+++ Sbjct: 47 SGRTDKGVHATAQVIHFDLPPFWSELERLQNLLNESLRPYIQIKRVVKVPKEFHARYSAK 106 Query: 611 ARSYSYTL 634 R+Y Y L Sbjct: 107 RRAYRYLL 114 >UniRef50_A5KCH3 Cluster: Pseudouridylate synthase 1, putative; n=1; Plasmodium vivax|Rep: Pseudouridylate synthase 1, putative - Plasmodium vivax Length = 587 Score = 37.9 bits (84), Expect = 0.21 Identities = 15/37 (40%), Positives = 23/37 (62%) Frame = +2 Query: 527 INKRLPETIKVFAVKRVTNRFNSKSKCNARSYSYTLP 637 +N+ LPE I+ F + RVT F+++ C+ R Y Y P Sbjct: 191 LNEHLPEDIRCFDMHRVTKSFDARKFCSFRLYEYLFP 227 >UniRef50_Q8R7Y7 Cluster: tRNA pseudouridine synthase A; n=9; Clostridia|Rep: tRNA pseudouridine synthase A - Thermoanaerobacter tengcongensis Length = 240 Score = 37.9 bits (84), Expect = 0.21 Identities = 21/67 (31%), Positives = 34/67 (50%), Gaps = 4/67 (5%) Frame = +2 Query: 446 SSRTDKGVSAAEQVVSLKLPLEVNVEEI----NKRLPETIKVFAVKRVTNRFNSKSKCNA 613 SSRTD GV A QV + K ++ E++ N LP+ + V K V F+++ + Sbjct: 44 SSRTDTGVHALYQVANFKTKTKIPPEKLPYALNAVLPDDVVVVKAKEVDKSFHARYSARS 103 Query: 614 RSYSYTL 634 + Y Y + Sbjct: 104 KRYRYLI 110 >UniRef50_Q7TU07 Cluster: tRNA pseudouridine synthase A; n=1; Pirellula sp.|Rep: tRNA pseudouridine synthase A - Rhodopirellula baltica Length = 276 Score = 37.9 bits (84), Expect = 0.21 Identities = 24/66 (36%), Positives = 33/66 (50%), Gaps = 5/66 (7%) Frame = +2 Query: 446 SSRTDKGVSAAEQVVSLKLPL----EVNVEE-INKRLPETIKVFAVKRVTNRFNSKSKCN 610 S RTD GV A QV LP+ V ++ IN +LP I+V AV+ RF+ + Sbjct: 54 SGRTDAGVHAIGQVARCVLPVWKADTVALQRAINSKLPNDIRVKAVRETRERFHPIADAT 113 Query: 611 ARSYSY 628 + Y Y Sbjct: 114 GKQYQY 119 >UniRef50_Q4AHD2 Cluster: TRNA pseudouridine synthase; n=1; Chlorobium phaeobacteroides BS1|Rep: TRNA pseudouridine synthase - Chlorobium phaeobacteroides BS1 Length = 240 Score = 37.5 bits (83), Expect = 0.27 Identities = 20/68 (29%), Positives = 38/68 (55%), Gaps = 5/68 (7%) Frame = +2 Query: 452 RTDKGVSAAEQVVSLKLP-LEVNVEEI----NKRLPETIKVFAVKRVTNRFNSKSKCNAR 616 RTD GV A + +P +E N+ ++ N+ LP+ + V+ ++ V + +S+ N+R Sbjct: 55 RTDTGVHARAFYAHIDIPAIESNLNDLVYKLNRFLPDDLVVYFIQEVPHDLHSRFSANSR 114 Query: 617 SYSYTLPT 640 +Y Y + T Sbjct: 115 TYKYYIST 122 >UniRef50_Q11XU3 Cluster: Pseudouridylate synthase; n=1; Cytophaga hutchinsonii ATCC 33406|Rep: Pseudouridylate synthase - Cytophaga hutchinsonii (strain ATCC 33406 / NCIMB 9469) Length = 248 Score = 37.5 bits (83), Expect = 0.27 Identities = 30/117 (25%), Positives = 52/117 (44%), Gaps = 5/117 (4%) Frame = +2 Query: 299 LGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQ--RSSRTDKGVS 472 + Y G Y+G Q T+ + Q+ N A+ S RTD GV Sbjct: 7 ISYRGANYHGWQIQENAVTVQG-----------VLQKALSNVLGAKIDILGSGRTDTGVH 55 Query: 473 AAEQVVSLKLPLEVN---VEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYSYTL 634 A+ Q+V L P E++ + IN LP+ I + + + V + +++ +R+Y Y + Sbjct: 56 ASSQIVHLDSPKEIDAALIFRINGYLPKDICIKSARLVQDDAHARFDALSRAYVYRI 112 >UniRef50_A6TWE8 Cluster: Pseudouridylate synthase; n=4; Clostridia|Rep: Pseudouridylate synthase - Alkaliphilus metalliredigens QYMF Length = 255 Score = 37.1 bits (82), Expect = 0.36 Identities = 21/67 (31%), Positives = 32/67 (47%), Gaps = 4/67 (5%) Frame = +2 Query: 446 SSRTDKGVSAAEQVVSLKLPLEVNVEEI----NKRLPETIKVFAVKRVTNRFNSKSKCNA 613 S RTD GV A QV S +L ++ E I N +LP I + K + F+++ Sbjct: 48 SGRTDAGVHAQGQVASFQLHSKIPAERISFALNGKLPRDITILEAKEMPEDFHARYSAIG 107 Query: 614 RSYSYTL 634 + Y Y + Sbjct: 108 KRYGYCI 114 >UniRef50_A3I2E1 Cluster: TRNA pseudouridine synthase A; n=1; Algoriphagus sp. PR1|Rep: TRNA pseudouridine synthase A - Algoriphagus sp. PR1 Length = 233 Score = 37.1 bits (82), Expect = 0.36 Identities = 22/65 (33%), Positives = 34/65 (52%), Gaps = 4/65 (6%) Frame = +2 Query: 446 SSRTDKGVSAAEQVVSLKLPLEVNVE----EINKRLPETIKVFAVKRVTNRFNSKSKCNA 613 +SRTD GVS V + L EV ++ + N+ LP+ I + +VK V+ FN Sbjct: 12 ASRTDSGVSCVGGFVQVFLRDEVEMDLLLPQFNEHLPQDIHLNSVKEVSTTFNLIQSVKK 71 Query: 614 RSYSY 628 ++Y Y Sbjct: 72 KTYRY 76 >UniRef50_Q7M9U3 Cluster: tRNA pseudouridine synthase A; n=2; Wolinella succinogenes|Rep: tRNA pseudouridine synthase A - Wolinella succinogenes Length = 253 Score = 37.1 bits (82), Expect = 0.36 Identities = 21/68 (30%), Positives = 37/68 (54%), Gaps = 5/68 (7%) Frame = +2 Query: 446 SSRTDKGVSAAEQVVSLKLPLEVN-----VEEINKRLPETIKVFAVKRVTNRFNSKSKCN 610 S RTD+GV A Q VS ++P + + EE+NK+L ++V + + + + + Sbjct: 47 SGRTDRGVHATRQAVSFEVPYKKSDWGYFKEELNKKLFPYLRVRRLYPIREGLDPRFEAK 106 Query: 611 ARSYSYTL 634 +R+Y Y L Sbjct: 107 SRAYRYLL 114 >UniRef50_Q72DL8 Cluster: tRNA pseudouridine synthase A; n=2; Desulfovibrio vulgaris subsp. vulgaris|Rep: tRNA pseudouridine synthase A - Desulfovibrio vulgaris (strain Hildenborough / ATCC 29579 / NCIMB8303) Length = 297 Score = 37.1 bits (82), Expect = 0.36 Identities = 22/74 (29%), Positives = 40/74 (54%), Gaps = 4/74 (5%) Frame = +2 Query: 425 QNAQFQRSSRTDKGVSAAEQVVSLKLP---LEVNVEE-INKRLPETIKVFAVKRVTNRFN 592 + + + RTD GV A QV + +P L V+ ++ IN +LP+ I + V+R + F+ Sbjct: 46 EQVRLHAAGRTDAGVHADGQVAHVDIPDHKLGVDWQKAINAQLPDDICILDVRRAADDFH 105 Query: 593 SKSKCNARSYSYTL 634 ++ + Y+Y L Sbjct: 106 ARFDALGKRYTYRL 119 >UniRef50_Q890R5 Cluster: tRNA pseudouridine synthase A 2; n=11; Clostridium|Rep: tRNA pseudouridine synthase A 2 - Clostridium tetani Length = 248 Score = 37.1 bits (82), Expect = 0.36 Identities = 22/67 (32%), Positives = 33/67 (49%), Gaps = 4/67 (5%) Frame = +2 Query: 446 SSRTDKGVSAAEQVVSLK----LPLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNA 613 SSRTD GV A + K +P E +N+ LPE I + + V F+S+ C Sbjct: 51 SSRTDAGVHALAYTANFKTCSTIPGEKFKHALNRFLPEDIVILESEEVPMEFHSRFDCIG 110 Query: 614 RSYSYTL 634 ++Y Y + Sbjct: 111 KTYVYKI 117 >UniRef50_Q6I3T8 Cluster: tRNA pseudouridine synthase A 2; n=12; Bacillus|Rep: tRNA pseudouridine synthase A 2 - Bacillus anthracis Length = 245 Score = 37.1 bits (82), Expect = 0.36 Identities = 22/66 (33%), Positives = 38/66 (57%), Gaps = 4/66 (6%) Frame = +2 Query: 449 SRTDKGVSAAEQVVSLKLP---LEVNVEE-INKRLPETIKVFAVKRVTNRFNSKSKCNAR 616 SRTD GV A QV + + +E V++ +N+ LP I + V+ V +RF+++ A+ Sbjct: 50 SRTDAGVHALNQVANFQSDEKLVEHKVKKYLNQYLPNDISITNVEEVHDRFHARYNSKAK 109 Query: 617 SYSYTL 634 +Y Y + Sbjct: 110 TYLYKI 115 >UniRef50_Q21IY8 Cluster: Pseudouridylate synthase; n=2; Gammaproteobacteria|Rep: Pseudouridylate synthase - Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024) Length = 289 Score = 36.7 bits (81), Expect = 0.48 Identities = 20/67 (29%), Positives = 35/67 (52%), Gaps = 4/67 (5%) Frame = +2 Query: 446 SSRTDKGVSAAEQVVSLKL----PLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNA 613 + RTD GV A Q+V P + ++ +N LP +I+V + K V F+++ + Sbjct: 70 AGRTDAGVHATSQIVHFDTLAGRPSKAWLQGVNTHLPFSIRVISAKEVGFDFHARFSALS 129 Query: 614 RSYSYTL 634 R+Y Y + Sbjct: 130 RTYRYVI 136 >UniRef50_Q6G7A2 Cluster: tRNA pseudouridine synthase A; n=16; Staphylococcus|Rep: tRNA pseudouridine synthase A - Staphylococcus aureus (strain MSSA476) Length = 267 Score = 36.7 bits (81), Expect = 0.48 Identities = 22/72 (30%), Positives = 36/72 (50%), Gaps = 4/72 (5%) Frame = +2 Query: 425 QNAQFQRSSRTDKGVSAAEQV----VSLKLPLEVNVEEINKRLPETIKVFAVKRVTNRFN 592 ++ + SSRTD+GV A +Q L +P+ +N+ LP+ I V V V + F+ Sbjct: 40 RHVRIHPSSRTDRGVHAIQQYFHFDTELNIPMSQWQYAMNRTLPDDIYVNNVVTVDDDFH 99 Query: 593 SKSKCNARSYSY 628 + C + Y Y Sbjct: 100 CRYDCVGKRYRY 111 >UniRef50_A0ZG49 Cluster: Pseudouridylate synthase; n=3; Cyanobacteria|Rep: Pseudouridylate synthase - Nodularia spumigena CCY 9414 Length = 296 Score = 36.3 bits (80), Expect = 0.63 Identities = 23/69 (33%), Positives = 34/69 (49%), Gaps = 4/69 (5%) Frame = +2 Query: 446 SSRTDKGVSAAEQVVSLK----LPLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNA 613 + RTD GV AA QV + +P +N LP+ I + A V NR++++ Sbjct: 58 AGRTDSGVHAAAQVAHFEATGLIPPHRWASILNSYLPQDILIKASAAVDNRWHARFSAAY 117 Query: 614 RSYSYTLPT 640 R Y YT+ T Sbjct: 118 RRYRYTIYT 126 >UniRef50_Q9C5K6 Cluster: Pseudouridylate synthase; n=3; core eudicotyledons|Rep: Pseudouridylate synthase - Arabidopsis thaliana (Mouse-ear cress) Length = 446 Score = 36.3 bits (80), Expect = 0.63 Identities = 45/201 (22%), Positives = 81/201 (40%), Gaps = 22/201 (10%) Frame = +2 Query: 92 LAITSARLLSVMEAADVTKDEENKSIDIVPNKLLTRYNKRRAHRDWETKPPGEIKKPYER 271 L + +A+LLS + + + E + + L R +RR + + P + Sbjct: 35 LEVENAKLLSQVSSCQCQQMEVKHDRSLSDSSSLVR--RRRVRKGDKNSIPSHL------ 86 Query: 272 IKRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSS 451 I ++ +A+ + Y G +YG ++ + D +++ + R Sbjct: 87 ISKRYVALKIMYFGKRFYGFSAEAQMEPSIESEVFKALERTRLLVGD---KKDSCYSRCG 143 Query: 452 RTDKGVSAAEQVVS------LKLP-----LEVN-----------VEEINKRLPETIKVFA 565 RTDKGVS+ QV++ LK P +VN V +N+ LP+ I+V Sbjct: 144 RTDKGVSSTGQVIALFLRSRLKSPPGDSKAQVNGRTGERPEYDYVRVLNRALPDDIRVIG 203 Query: 566 VKRVTNRFNSKSKCNARSYSY 628 F+++ C AR Y Y Sbjct: 204 WSPAPIDFHARFSCYAREYKY 224 >UniRef50_Q011R7 Cluster: Exopolyphosphatases and related proteins; n=3; Ostreococcus|Rep: Exopolyphosphatases and related proteins - Ostreococcus tauri Length = 813 Score = 36.3 bits (80), Expect = 0.63 Identities = 23/77 (29%), Positives = 36/77 (46%), Gaps = 9/77 (11%) Frame = +2 Query: 425 QNAQFQRSSRTDKGVSAAEQVVSLKL-------PLEV--NVEEINKRLPETIKVFAVKRV 577 + A + R RTD+GVS Q+V+L++ P E V +N+ LP ++ V Sbjct: 504 KTASYARCGRTDRGVSGLGQIVTLQVRSNGASDPREELDYVGLLNRALPSDVRALGWAPV 563 Query: 578 TNRFNSKSKCNARSYSY 628 N++ C R Y Y Sbjct: 564 DEELNARFDCKWRQYKY 580 >UniRef50_Q7TU31 Cluster: tRNA pseudouridine synthase A; n=5; Prochlorococcus marinus|Rep: tRNA pseudouridine synthase A - Prochlorococcus marinus subsp. pastoris (strain CCMP 1378 / MED4) Length = 268 Score = 36.3 bits (80), Expect = 0.63 Identities = 20/67 (29%), Positives = 34/67 (50%), Gaps = 4/67 (5%) Frame = +2 Query: 446 SSRTDKGVSAAEQVVSLKL----PLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNA 613 S RTD GV A+ QV+ + P++ + +N RLP TI++ V + +++ Sbjct: 48 SGRTDAGVHASGQVIHFDIDFLIPIDRYADVLNSRLPHTIRILESVEVKSSWHACYSAVY 107 Query: 614 RSYSYTL 634 R Y Y + Sbjct: 108 RHYRYVI 114 >UniRef50_A6NVS7 Cluster: Pseudouridylate synthase; n=1; Bacteroides capillosus ATCC 29799|Rep: Pseudouridylate synthase - Bacteroides capillosus ATCC 29799 Length = 249 Score = 35.9 bits (79), Expect = 0.83 Identities = 20/67 (29%), Positives = 32/67 (47%), Gaps = 4/67 (5%) Frame = +2 Query: 446 SSRTDKGVSAAEQVVSLK----LPLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNA 613 + RTD GV A + + + +P + +N RLPE I V V + FN+ C Sbjct: 48 AGRTDAGVHAENYIANFRTTSTIPCDRLPLAVNTRLPEDIVVVKATEVHDGFNAIGSCIK 107 Query: 614 RSYSYTL 634 + Y+Y + Sbjct: 108 KEYTYRI 114 >UniRef50_Q0UN59 Cluster: Putative uncharacterized protein; n=1; Phaeosphaeria nodorum|Rep: Putative uncharacterized protein - Phaeosphaeria nodorum (Septoria nodorum) Length = 498 Score = 35.9 bits (79), Expect = 0.83 Identities = 20/52 (38%), Positives = 28/52 (53%), Gaps = 5/52 (9%) Frame = +1 Query: 247 RNQKTIRKD*EKKNGYAAGVLRS*IL---RYA--TKSWCTNNRRRIIKSIVG 387 R+ T R + EK+NGY + S +L YA KSWC N +I+ S+ G Sbjct: 168 RSADTRRDEAEKRNGYITRPMNSFMLYRSAYAERAKSWCAQNNHQIVSSVAG 219 >UniRef50_Q72I65 Cluster: tRNA pseudouridine synthase A; n=3; Thermus thermophilus|Rep: tRNA pseudouridine synthase A - Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) Length = 253 Score = 35.9 bits (79), Expect = 0.83 Identities = 21/67 (31%), Positives = 33/67 (49%), Gaps = 4/67 (5%) Frame = +2 Query: 446 SSRTDKGVSAAEQV----VSLKLPLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNA 613 + RTD GV A V +P+E E +N+ LPE +KV + V F+++ Sbjct: 48 AGRTDAGVHALAMPFHVDVESAIPVEKVPEALNRLLPEDLKVVGAREVAPDFHARKDALW 107 Query: 614 RSYSYTL 634 R+Y Y + Sbjct: 108 RAYRYRI 114 >UniRef50_Q47HQ7 Cluster: Pseudouridylate synthase; n=1; Dechloromonas aromatica RCB|Rep: Pseudouridylate synthase - Dechloromonas aromatica (strain RCB) Length = 262 Score = 35.5 bits (78), Expect = 1.1 Identities = 21/67 (31%), Positives = 30/67 (44%), Gaps = 4/67 (5%) Frame = +2 Query: 446 SSRTDKGVSAAEQVVSLKLPLE----VNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNA 613 + RTD GV A QV P++ V +N LPE + V + V F+++ Sbjct: 47 AGRTDAGVHATHQVAHFDAPVDRPLTAWVRGVNSHLPEGVAVRWAQPVAEDFHARFSARG 106 Query: 614 RSYSYTL 634 R Y Y L Sbjct: 107 RRYRYLL 113 >UniRef50_A6BIC3 Cluster: Pseudouridylate synthase; n=1; Dorea longicatena DSM 13814|Rep: Pseudouridylate synthase - Dorea longicatena DSM 13814 Length = 245 Score = 35.5 bits (78), Expect = 1.1 Identities = 19/65 (29%), Positives = 32/65 (49%), Gaps = 4/65 (6%) Frame = +2 Query: 452 RTDKGVSAAEQVVSLKLPLEVNVEEI----NKRLPETIKVFAVKRVTNRFNSKSKCNARS 619 RT+ GV A Q+ + K + I N+ LP I + VK V RF+++ +++ Sbjct: 54 RTEVGVHAYAQIANFKTSSSTTTQNIKHYLNRYLPMDIAIIDVKEVPERFHAQLNATSKT 113 Query: 620 YSYTL 634 Y Y + Sbjct: 114 YVYRM 118 >UniRef50_Q4SEJ2 Cluster: Pseudouridylate synthase; n=3; Tetraodontidae|Rep: Pseudouridylate synthase - Tetraodon nigroviridis (Green puffer) Length = 412 Score = 35.1 bits (77), Expect = 1.5 Identities = 35/147 (23%), Positives = 58/147 (39%), Gaps = 27/147 (18%) Frame = +2 Query: 278 RKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRT 457 R+ +A+ L Y G Y G + Q+ Q++ + R RT Sbjct: 72 RRHVALRLAYLGWAYQGFAVQENTDNTVEARLFEALHKTCLIQD----RQSSNYHRCGRT 127 Query: 458 DKGVSAAEQVVSL-------------KLPLEVN--------------VEEINKRLPETIK 556 DKGVSA QV+++ KLP V+ V+ +N+ LP I+ Sbjct: 128 DKGVSAFSQVITIESRSTQFCGGLGVKLPENVDADKKSQTAVSELPYVKMLNRVLPHDIR 187 Query: 557 VFAVKRVTNRFNSKSKCNARSYSYTLP 637 ++ F+++ C +R+Y Y P Sbjct: 188 IWNWAPAAEGFSARFDCQSRTYRYYFP 214 >UniRef50_Q1Q1P7 Cluster: Pseudouridylate synthase; n=1; Candidatus Kuenenia stuttgartiensis|Rep: Pseudouridylate synthase - Candidatus Kuenenia stuttgartiensis Length = 244 Score = 35.1 bits (77), Expect = 1.5 Identities = 20/74 (27%), Positives = 36/74 (48%), Gaps = 4/74 (5%) Frame = +2 Query: 425 QNAQFQRSSRTDKGVSAAEQVVSLK----LPLEVNVEEINKRLPETIKVFAVKRVTNRFN 592 + + + RTD GV A QV + K +P + + IN LP+ I + V + F+ Sbjct: 41 EEVEIHGAGRTDAGVHALGQVANFKTYSAIPAKQLLRAINFHLPQDITIKDVADMEEGFH 100 Query: 593 SKSKCNARSYSYTL 634 ++ ++ Y YT+ Sbjct: 101 ARYSATSKVYRYTV 114 >UniRef50_A7HKV8 Cluster: tRNA pseudouridine synthase A; n=1; Fervidobacterium nodosum Rt17-B1|Rep: tRNA pseudouridine synthase A - Fervidobacterium nodosum Rt17-B1 Length = 246 Score = 35.1 bits (77), Expect = 1.5 Identities = 32/125 (25%), Positives = 52/125 (41%), Gaps = 5/125 (4%) Frame = +2 Query: 281 KKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTD 460 +++A+ Y G +++G Q V+T+ I + + + RTD Sbjct: 2 RRVAIEFSYDGTDFFGYQIQNNVRTVQGELEKALEKVFKIHIDTYA---------AGRTD 52 Query: 461 KGVSAAEQVVSLKLP----LEVNVEE-INKRLPETIKVFAVKRVTNRFNSKSKCNARSYS 625 GV A QVVS P +E +++ IN LP I + V FN + + R Y Sbjct: 53 TGVHANGQVVSFDCPNDRLMENDIKNAINANLPGDIYIKKVWFTHPTFNPRYEAKRRIYH 112 Query: 626 YTLPT 640 Y + T Sbjct: 113 YYIDT 117 >UniRef50_A7SJV8 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 464 Score = 35.1 bits (77), Expect = 1.5 Identities = 38/164 (23%), Positives = 67/164 (40%), Gaps = 27/164 (16%) Frame = +2 Query: 230 ETKPPGEIKKPYERIKRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQE 409 ++KP E + R +++A+ L Y G + +G + + + Sbjct: 65 KSKPRKEFD--FSRYNTRRIALRLSYLGWDMHGFASQEKIDNTVEAHLFDALIKACLVK- 121 Query: 410 DFENAQNAQFQRSSRTDKGVSAAEQVVSLKLPLEVN---------------------VEE 526 + ++ + R RTDKGVSA QV+SL + ++ ++E Sbjct: 122 ---SRESCSYSRCGRTDKGVSAFGQVISLNVRTNLDKGPGVILRQESSVGRDTKGKTMKE 178 Query: 527 I------NKRLPETIKVFAVKRVTNRFNSKSKCNARSYSYTLPT 640 I NK LP+ I+V A V F+++ C+ R Y Y P+ Sbjct: 179 ILYVDILNKVLPKEIRVLAWAPVELDFDARFSCSYRKYKYLFPS 222 >UniRef50_A7ANH8 Cluster: tRNA pseudouridine synthase A family protein; n=1; Babesia bovis|Rep: tRNA pseudouridine synthase A family protein - Babesia bovis Length = 248 Score = 35.1 bits (77), Expect = 1.5 Identities = 20/54 (37%), Positives = 27/54 (50%) Frame = +2 Query: 467 VSAAEQVVSLKLPLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYSY 628 VS E+ V + + INK LP I+V VK V + F+S+ C R Y Y Sbjct: 92 VSPDERGVGPCYRINTFTKAINKHLPRGIRVNWVKHVPDDFSSRRNCTFRVYKY 145 >UniRef50_Q9KTA4 Cluster: tRNA pseudouridine synthase A; n=29; Gammaproteobacteria|Rep: tRNA pseudouridine synthase A - Vibrio cholerae Length = 264 Score = 35.1 bits (77), Expect = 1.5 Identities = 32/121 (26%), Positives = 47/121 (38%), Gaps = 4/121 (3%) Frame = +2 Query: 284 KMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTDK 463 ++A+ + Y G YYG QR V+++ I E Q + RTD Sbjct: 2 RIALGIEYDGTHYYGWQRQREVKSVQEALEKALSK---IANHPVE------VQCAGRTDA 52 Query: 464 GVSAAEQVVSLKLPLEVNVEE----INKRLPETIKVFAVKRVTNRFNSKSKCNARSYSYT 631 GV QVV E + N LP+ I V V + F+++ AR Y Y Sbjct: 53 GVHGTGQVVHFDTTAERQMVAWTMGANANLPKDIAVRWAMAVPDEFHARFSATARRYRYV 112 Query: 632 L 634 + Sbjct: 113 I 113 >UniRef50_Q6I4Q2 Cluster: tRNA pseudouridine synthase A 1; n=14; Bacillaceae|Rep: tRNA pseudouridine synthase A 1 - Bacillus anthracis Length = 247 Score = 35.1 bits (77), Expect = 1.5 Identities = 26/114 (22%), Positives = 46/114 (40%), Gaps = 4/114 (3%) Frame = +2 Query: 299 LGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTDKGVSAA 478 + Y G+ + G Q P +T+ + + + Q S RTD V A Sbjct: 8 VAYDGMHFCGYQIQPQHRTVQQEIEKAL--------QKLHKGELVRVQASGRTDSTVHAK 59 Query: 479 EQVVSLKLPLEVNVEE----INKRLPETIKVFAVKRVTNRFNSKSKCNARSYSY 628 QV+ PL + + +N LP+ I + V++ T F+++ + Y Y Sbjct: 60 GQVIHFDTPLSLEEWQWSNALNTMLPDDIVITQVEKKTEEFHARYGVERKEYRY 113 >UniRef50_Q0AUL4 Cluster: Pseudouridylate synthase; n=1; Syntrophomonas wolfei subsp. wolfei str. Goettingen|Rep: Pseudouridylate synthase - Syntrophomonas wolfei subsp. wolfei (strain Goettingen) Length = 249 Score = 34.7 bits (76), Expect = 1.9 Identities = 29/121 (23%), Positives = 47/121 (38%), Gaps = 4/121 (3%) Frame = +2 Query: 284 KMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTDK 463 ++ +LL Y G Y+G Q T+ + + A + RTD Sbjct: 3 RIKLLLEYDGSNYHGFQLQKNANTVQAELEKAIYRL---------SGERATIVCAGRTDA 53 Query: 464 GVSAAEQVVSLK----LPLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYSYT 631 GV A QVV+ +P + +N +LPE I+V + FN + + Y Y Sbjct: 54 GVHAWGQVVAFDSCSTIPGDRWAYALNSQLPEDIQVLESQETRAEFNPRFDALKKCYGYL 113 Query: 632 L 634 + Sbjct: 114 I 114 >UniRef50_A5I338 Cluster: Pseudouridylate synthase; n=7; Clostridiaceae|Rep: Pseudouridylate synthase - Clostridium botulinum A str. ATCC 3502 Length = 246 Score = 34.7 bits (76), Expect = 1.9 Identities = 21/67 (31%), Positives = 33/67 (49%), Gaps = 4/67 (5%) Frame = +2 Query: 446 SSRTDKGVSAAEQVVSLKLPLEVNVEEI----NKRLPETIKVFAVKRVTNRFNSKSKCNA 613 S RTD GV A QV + + + +EI + LP+ I V+ V RF+S+ Sbjct: 49 SGRTDTGVHANMQVANFHTTFQGSTDEILSYCYEYLPKDIVVYDAFHVDERFHSRLNVKK 108 Query: 614 RSYSYTL 634 + Y+Y + Sbjct: 109 KKYTYKI 115 >UniRef50_P60351 Cluster: tRNA pseudouridine synthase A; n=2; Candidatus Phytoplasma asteris|Rep: tRNA pseudouridine synthase A - Onion yellows phytoplasma Length = 243 Score = 34.7 bits (76), Expect = 1.9 Identities = 28/116 (24%), Positives = 47/116 (40%), Gaps = 4/116 (3%) Frame = +2 Query: 293 MLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTDKGVS 472 ++L Y G YYG Q+ P T+ + QN +SRTDKGV Sbjct: 8 LILSYDGTCYYGYQKQPQKITVQQTFEKALKKMTH---------QNIPTFAASRTDKGVH 58 Query: 473 AAEQVVSLKLPLEVN----VEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYSY 628 + Q + + + + +N LP I+V + T F+++ ++ Y Y Sbjct: 59 SQGQTLHFQTTFFLKPTHFQKTLNYLLPPDIRVRQMNFATPNFHARYSAKSKIYQY 114 >UniRef50_UPI000023D4AE Cluster: hypothetical protein FG10837.1; n=1; Gibberella zeae PH-1|Rep: hypothetical protein FG10837.1 - Gibberella zeae PH-1 Length = 538 Score = 34.3 bits (75), Expect = 2.5 Identities = 30/116 (25%), Positives = 47/116 (40%), Gaps = 4/116 (3%) Frame = +2 Query: 233 TKPPGEIKKPYERIKRKKMAMLLGYSGVEYYGM--QRNPGVQTIXXXXXXXXXXXXYITQ 406 TKP + K + + +A+ L Y G Y G Q +I I Sbjct: 45 TKPKVKRKMDPNKYTTRYIALKLAYLGKNYGGFEFQAMANAPSIEEELWNALTKACLIFP 104 Query: 407 ED--FENAQNAQFQRSSRTDKGVSAAEQVVSLKLPLEVNVEEINKRLPETIKVFAV 568 ED + ++ + RTDKGVSA QV+ L++ V + +R+ E + V Sbjct: 105 EDERIVDFDCCEYSKCGRTDKGVSAFGQVIGLRVRSARPVPKKRRRMSEAGEAMVV 160 >UniRef50_Q30RV9 Cluster: Pseudouridylate synthase; n=1; Thiomicrospira denitrificans ATCC 33889|Rep: Pseudouridylate synthase - Thiomicrospira denitrificans (strain ATCC 33889 / DSM 1351) Length = 236 Score = 34.3 bits (75), Expect = 2.5 Identities = 20/68 (29%), Positives = 35/68 (51%), Gaps = 5/68 (7%) Frame = +2 Query: 446 SSRTDKGVSAAEQVVSLKLP-----LEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCN 610 S RTD+GV A+ QV + LP + + + + LP +I + +K V + F+++ Sbjct: 47 SGRTDRGVHASGQVCHIDLPPYWSDITKLQDSLGRVLPPSILIKKIKIVDDTFHARYSAK 106 Query: 611 ARSYSYTL 634 R Y Y + Sbjct: 107 RRVYRYII 114 >UniRef50_Q8GB97 Cluster: Pseudouridylate synthase; n=2; Clostridiales|Rep: Pseudouridylate synthase - Heliobacillus mobilis Length = 249 Score = 34.3 bits (75), Expect = 2.5 Identities = 28/116 (24%), Positives = 45/116 (38%), Gaps = 4/116 (3%) Frame = +2 Query: 299 LGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTDKGVSAA 478 + Y G Y+G Q + +T E+ + + RTD GV A Sbjct: 1 MSYDGTSYHGFQTQEDPTNLPTIQDELMRAIQVLTGEE------VKITCAGRTDAGVHAR 54 Query: 479 EQVVSL----KLPLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYSYTL 634 QVV ++P E +N LP+ I V + V F+S+ + Y Y++ Sbjct: 55 GQVVDFLTTSRIPDEKFPLAMNSLLPKDIAVVKAETVAEDFHSRFGALGKHYRYSI 110 >UniRef50_Q1FLK6 Cluster: Pseudouridylate synthase; n=1; Clostridium phytofermentans ISDg|Rep: Pseudouridylate synthase - Clostridium phytofermentans ISDg Length = 276 Score = 34.3 bits (75), Expect = 2.5 Identities = 30/122 (24%), Positives = 48/122 (39%), Gaps = 4/122 (3%) Frame = +2 Query: 281 KKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTD 460 + + +++ Y G Y G Q+ G Q EN + ++RT+ Sbjct: 30 RNIQLIIEYDGSRYDGWQKQAGNQKSITIQDKLEDVL-----NKMEN-ETVTVIGAARTE 83 Query: 461 KGVSAAEQVVSLKLPLEVNVEEI----NKRLPETIKVFAVKRVTNRFNSKSKCNARSYSY 628 GV A +QV S ++ V EI N+ LP I V V RF++ + Y Y Sbjct: 84 AGVHAYKQVASFMTNSKLKVYEIKQYLNRFLPRDIAVLEALEVPERFHASFNAGSFEYEY 143 Query: 629 TL 634 + Sbjct: 144 KI 145 >UniRef50_A7I1Z3 Cluster: tRNA pseudouridine synthase A; n=1; Campylobacter hominis ATCC BAA-381|Rep: tRNA pseudouridine synthase A - Campylobacter hominis (strain ATCC BAA-381 / LMG 19568 / NCTC 13146 /CH001A) Length = 278 Score = 34.3 bits (75), Expect = 2.5 Identities = 23/73 (31%), Positives = 34/73 (46%), Gaps = 4/73 (5%) Frame = +2 Query: 428 NAQFQRSSRTDKGVSAAEQVVSLKLPLEVNVEE----INKRLPETIKVFAVKRVTNRFNS 595 N + +SRTDKGV A QV + +++ IN+ +I V ++R F Sbjct: 44 NEKVISASRTDKGVHALSQVSTTHCAAFWDLQNLRHFINRHAKPSIYVRKIERADENFQV 103 Query: 596 KSKCNARSYSYTL 634 + ARSY Y L Sbjct: 104 RFDAKARSYRYIL 116 >UniRef50_A0RNY9 Cluster: Pseudouridylate synthase; n=2; Campylobacter|Rep: Pseudouridylate synthase - Campylobacter fetus subsp. fetus (strain 82-40) Length = 258 Score = 34.3 bits (75), Expect = 2.5 Identities = 23/69 (33%), Positives = 35/69 (50%), Gaps = 6/69 (8%) Frame = +2 Query: 446 SSRTDKGVSAAEQVVSLKLP------LEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKC 607 SSRTDKGV A QV ++ E +INK I + +++V++ F+ + Sbjct: 47 SSRTDKGVHAISQVSCVECGEFWNERFERLKNQINKHTKPYIYIKNIQKVSDEFHPRYDA 106 Query: 608 NARSYSYTL 634 ARSY Y + Sbjct: 107 VARSYRYII 115 >UniRef50_A5E5W9 Cluster: Putative uncharacterized protein; n=1; Lodderomyces elongisporus NRRL YB-4239|Rep: Putative uncharacterized protein - Lodderomyces elongisporus (Yeast) (Saccharomyces elongisporus) Length = 380 Score = 34.3 bits (75), Expect = 2.5 Identities = 18/70 (25%), Positives = 36/70 (51%), Gaps = 1/70 (1%) Frame = +2 Query: 398 ITQEDFENAQNAQFQRSSRTDKGVSAAEQVVSLKLPLEVNVEEINKRLPETIK-VFAVKR 574 ++QE+FENA+ + + D V + V K E EE+ K+L ++ ++ + Sbjct: 240 LSQEEFENAKQNYMNLAKKVDDAVCVSVDGVLYKSRTEEENEELKKKLLSQLETLYETEA 299 Query: 575 VTNRFNSKSK 604 +N + SK++ Sbjct: 300 ASNEYRSKAQ 309 >UniRef50_Q6MEE7 Cluster: tRNA pseudouridine synthase A 1; n=1; Candidatus Protochlamydia amoebophila UWE25|Rep: tRNA pseudouridine synthase A 1 - Protochlamydia amoebophila (strain UWE25) Length = 256 Score = 34.3 bits (75), Expect = 2.5 Identities = 22/67 (32%), Positives = 33/67 (49%), Gaps = 4/67 (5%) Frame = +2 Query: 446 SSRTDKGVSAAEQVVSLKLPLEVNVEEI----NKRLPETIKVFAVKRVTNRFNSKSKCNA 613 S RTD GV A QV +++ + N LP I++ AV+ V+ RF+S+ Sbjct: 49 SGRTDAGVHAKGQVAHFHFQDYIDLSRLHVSLNGLLPRDIRIKAVEPVSPRFHSQYSAIR 108 Query: 614 RSYSYTL 634 + Y Y L Sbjct: 109 KEYHYYL 115 >UniRef50_UPI0000E48924 Cluster: PREDICTED: similar to FKSG32, partial; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to FKSG32, partial - Strongylocentrotus purpuratus Length = 224 Score = 33.9 bits (74), Expect = 3.4 Identities = 23/87 (26%), Positives = 41/87 (47%), Gaps = 2/87 (2%) Frame = +2 Query: 248 EIKKPYE--RIKRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFEN 421 +I +P++ + + +A+ + Y G +Y+G VQ + E+ Sbjct: 50 KIPRPFDFKKYNTRHVALKITYLGWDYHGFV----VQEDSNNTVEHHLFEALTKTKLIES 105 Query: 422 AQNAQFQRSSRTDKGVSAAEQVVSLKL 502 Q + + R RTDKGVSA QV+++ L Sbjct: 106 RQTSNYSRCGRTDKGVSAFGQVIAIDL 132 >UniRef50_Q4ALX6 Cluster: Pseudouridylate synthase; n=1; Chlorobium phaeobacteroides BS1|Rep: Pseudouridylate synthase - Chlorobium phaeobacteroides BS1 Length = 233 Score = 33.9 bits (74), Expect = 3.4 Identities = 29/117 (24%), Positives = 51/117 (43%), Gaps = 5/117 (4%) Frame = +2 Query: 293 MLLGYSGVEYYGMQRNP-GVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTDKGV 469 M + Y G ++ G Q+ P GV T+ I QE+ + RTD+GV Sbjct: 1 MTIEYDGTDFSGWQKQPEGVVTVQGVLETTLSR---IVQEE------VVMTAAGRTDRGV 51 Query: 470 SAAEQVVSLKLPLEVN----VEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYSY 628 A QV + + ++ + +N LP T+ + ++ V + F+++ R Y Y Sbjct: 52 HARGQVANFRTASCLSTGRLLHSLNALLPSTVCIRDMQEVPDSFHARYSALFREYRY 108 >UniRef50_Q5CV63 Cluster: Pseudouridylate synthase; n=2; Cryptosporidium|Rep: Pseudouridylate synthase - Cryptosporidium parvum Iowa II Length = 283 Score = 33.9 bits (74), Expect = 3.4 Identities = 22/72 (30%), Positives = 32/72 (44%), Gaps = 7/72 (9%) Frame = +2 Query: 443 RSSRTDKGVSAAEQVVSLKLPLEVN-------VEEINKRLPETIKVFAVKRVTNRFNSKS 601 R RTD+GV +A +S+ L +E +N LP I+V V F+++ Sbjct: 42 RCGRTDRGVHSAGNYISVNLRTRAKNLEPYNYMEMLNGVLPWDIRVIGYCEVRPDFSARF 101 Query: 602 KCNARSYSYTLP 637 C R Y Y P Sbjct: 102 DCEYRLYKYFFP 113 >UniRef50_A0CKA3 Cluster: Chromosome undetermined scaffold_2, whole genome shotgun sequence; n=4; Paramecium tetraurelia|Rep: Chromosome undetermined scaffold_2, whole genome shotgun sequence - Paramecium tetraurelia Length = 429 Score = 33.9 bits (74), Expect = 3.4 Identities = 24/95 (25%), Positives = 46/95 (48%) Frame = +2 Query: 263 YERIKRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQ 442 ++++KR K+ L + + Y ++ PG+Q I TQE+ +N +N Q + Sbjct: 290 FQKLKRSKLQESLKHK-IHMYNPKQIPGIQKIIESIQTANNTIAKTTQENVQNEENKQ-E 347 Query: 443 RSSRTDKGVSAAEQVVSLKLPLEVNVEEINKRLPE 547 +S + D V Q V+ + +V E+N+ + E Sbjct: 348 QSDQGDNAV-IENQNVNQQEDNNNDVNEVNEAVNE 381 >UniRef50_Q30XU3 Cluster: Pseudouridylate synthase; n=2; Desulfovibrionaceae|Rep: Pseudouridylate synthase - Desulfovibrio desulfuricans (strain G20) Length = 278 Score = 33.5 bits (73), Expect = 4.4 Identities = 21/67 (31%), Positives = 34/67 (50%), Gaps = 4/67 (5%) Frame = +2 Query: 446 SSRTDKGVSAAEQVVSLKLP-LEVNVE---EINKRLPETIKVFAVKRVTNRFNSKSKCNA 613 + RTD GV A QV L +P + V+ +N +LPE I V V + F+++ Sbjct: 57 AGRTDSGVHAEGQVAHLDIPDAKAAVDWRRALNAKLPEDISVLQAAVVPDGFHARFDAVK 116 Query: 614 RSYSYTL 634 + Y+Y + Sbjct: 117 KRYTYRI 123 >UniRef50_A3ZQX0 Cluster: Pseudouridylate synthase; n=2; Bacteria|Rep: Pseudouridylate synthase - Blastopirellula marina DSM 3645 Length = 260 Score = 33.5 bits (73), Expect = 4.4 Identities = 21/67 (31%), Positives = 32/67 (47%), Gaps = 4/67 (5%) Frame = +2 Query: 446 SSRTDKGVSAAEQVVSLKLPLEVNVE----EINKRLPETIKVFAVKRVTNRFNSKSKCNA 613 S RTD GV A QVVS ++ +++ + +N LP I V + + FN+ Sbjct: 53 SGRTDSGVHAIGQVVSFRMQSQLSPDVMRRALNAELPPDIVVQSARNAIPEFNAIDCAIK 112 Query: 614 RSYSYTL 634 + Y Y L Sbjct: 113 KRYRYLL 119 >UniRef50_Q8ZXR6 Cluster: tRNA pseudouridine synthase A; n=4; Pyrobaculum|Rep: tRNA pseudouridine synthase A - Pyrobaculum aerophilum Length = 256 Score = 33.5 bits (73), Expect = 4.4 Identities = 20/65 (30%), Positives = 30/65 (46%) Frame = +2 Query: 443 RSSRTDKGVSAAEQVVSLKLPLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSY 622 R SRTD GVSA VV + + +N ++P+ + + V FN + + R Y Sbjct: 38 RGSRTDPGVSAVGNVVMTGRKMALGY--VNSKMPKGAWAWGIAEVPEGFNPR-RAKLRRY 94 Query: 623 SYTLP 637 Y P Sbjct: 95 LYVAP 99 >UniRef50_Q26G59 Cluster: Pseudouridylate synthase; n=5; Flavobacteria|Rep: Pseudouridylate synthase - Flavobacteria bacterium BBFL7 Length = 267 Score = 33.1 bits (72), Expect = 5.9 Identities = 28/115 (24%), Positives = 44/115 (38%), Gaps = 5/115 (4%) Frame = +2 Query: 299 LGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTDKGVSAA 478 L Y G ++G Q+ P V T+ T + N + + RTD VS Sbjct: 15 LQYLGFRFHGWQKQPDVPTVEKMVKR--------TLRFVLDHHNFKVLAAGRTDARVSVN 66 Query: 479 EQVVSL-----KLPLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNARSYSY 628 E ++ L L L+ + E N LP I+ ++ +FN + Y Y Sbjct: 67 ETIIELFLDDEALNLDTFLAEFNLNLPSDIRALDIEETNAQFNVIQHPKEKEYIY 121 >UniRef50_Q1NSM9 Cluster: Putative uncharacterized protein; n=1; delta proteobacterium MLMS-1|Rep: Putative uncharacterized protein - delta proteobacterium MLMS-1 Length = 90 Score = 33.1 bits (72), Expect = 5.9 Identities = 20/70 (28%), Positives = 33/70 (47%) Frame = +2 Query: 110 RLLSVMEAADVTKDEENKSIDIVPNKLLTRYNKRRAHRDWETKPPGEIKKPYERIKRKKM 289 R L+++ D E+ V + RY R +W+T GE K+ + RI R + Sbjct: 17 RSLALVNTYDARGAEKPAMGFTVAKRKGIRYVGGRGVTEWKTMAGGEKKRGHGRISRNPL 76 Query: 290 AMLLGYSGVE 319 +L+G G+E Sbjct: 77 ILLVGRIGIE 86 >UniRef50_Q7QX52 Cluster: Pseudouridylate synthase; n=1; Giardia lamblia ATCC 50803|Rep: Pseudouridylate synthase - Giardia lamblia ATCC 50803 Length = 351 Score = 33.1 bits (72), Expect = 5.9 Identities = 19/74 (25%), Positives = 37/74 (50%), Gaps = 1/74 (1%) Frame = +2 Query: 284 KMAMLLGYSGVEYYGMQRNP-GVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTD 460 ++A+L+ + G ++G P G T+ Y+ + E ++ + +R+ RTD Sbjct: 2 RVALLVAFHGTAFHGNAYQPTGGSTVEGALFEGLQKTGYLKEN--ETIKDIELERTGRTD 59 Query: 461 KGVSAAEQVVSLKL 502 GVSA + +L+L Sbjct: 60 AGVSAECMLYTLQL 73 >UniRef50_Q4N208 Cluster: Putative uncharacterized protein; n=1; Theileria parva|Rep: Putative uncharacterized protein - Theileria parva Length = 408 Score = 33.1 bits (72), Expect = 5.9 Identities = 20/81 (24%), Positives = 40/81 (49%) Frame = +2 Query: 395 YITQEDFENAQNAQFQRSSRTDKGVSAAEQVVSLKLPLEVNVEEINKRLPETIKVFAVKR 574 Y + N Q S T + ++ + V +L +P + V+ ++ P T++ +V + Sbjct: 180 YTRPTNLFNTNLTTIQSQSETPEYLNRVDNV-NLDIPAAIPVDTMDVN-PNTMENLSVDK 237 Query: 575 VTNRFNSKSKCNARSYSYTLP 637 V N FN+ + N+ +Y+ LP Sbjct: 238 VNNMFNTPNYLNSVNYTDNLP 258 >UniRef50_Q231M3 Cluster: Tubulin-tyrosine ligase family protein; n=1; Tetrahymena thermophila SB210|Rep: Tubulin-tyrosine ligase family protein - Tetrahymena thermophila SB210 Length = 993 Score = 33.1 bits (72), Expect = 5.9 Identities = 34/148 (22%), Positives = 62/148 (41%) Frame = +2 Query: 182 NKLLTRYNKRRAHRDWETKPPGEIKKPYERIKRKKMAMLLGYSGVEYYGMQRNPGVQTIX 361 N L + ++ ++ E + +++ + IK+KK+ ++ N + I Sbjct: 74 NNLKRKVKTQKVNQTKENQQTSQVQISSQEIKQKKLIHSAEDIDLQVKQFDVNANAEAIK 133 Query: 362 XXXXXXXXXXXYITQEDFENAQNAQFQRSSRTDKGVSAAEQVVSLKLPLEVNVEEINKRL 541 I QED EN +N Q QR + +K + K L+ NV + N +L Sbjct: 134 LEQLKKIDEAKAI-QEDLEN-RNKQRQRDMKLEKLPLNLSN--NNKKSLQ-NVSKRNPQL 188 Query: 542 PETIKVFAVKRVTNRFNSKSKCNARSYS 625 ET+ +++ + KS N +SYS Sbjct: 189 AETLDIYSQSSGIYQIMQKSLLNGQSYS 216 >UniRef50_A5E087 Cluster: Protein POS5; n=2; Saccharomycetales|Rep: Protein POS5 - Lodderomyces elongisporus (Yeast) (Saccharomyces elongisporus) Length = 535 Score = 33.1 bits (72), Expect = 5.9 Identities = 20/61 (32%), Positives = 30/61 (49%), Gaps = 7/61 (11%) Frame = +2 Query: 161 KSIDIVPNKLLTRYNKRRAHR----DWETKPPGEI---KKPYERIKRKKMAMLLGYSGVE 319 +S + +P L Y K + HR W T PP + KKP++ R+ M L+ + VE Sbjct: 87 ESCENLPKARLPDYVKSQQHRLFNIIWRTSPPKNVLMVKKPWDATVREAMIQLINHLHVE 146 Query: 320 Y 322 Y Sbjct: 147 Y 147 >UniRef50_P56144 Cluster: tRNA pseudouridine synthase A; n=4; Helicobacter|Rep: tRNA pseudouridine synthase A - Helicobacter pylori (Campylobacter pylori) Length = 242 Score = 33.1 bits (72), Expect = 5.9 Identities = 26/84 (30%), Positives = 41/84 (48%), Gaps = 7/84 (8%) Frame = +2 Query: 404 QEDFENAQNAQFQRS-----SRTDKGVSAAEQVVSLKLPLEVNVEEINKRL-PETIKVFA 565 Q+ E+A NA +S RTDKGV A QV+S P N ++ L P+ Sbjct: 28 QDKIEDALNALGIKSVVIAAGRTDKGVHANNQVLSFHAPKHWNAAKLFYYLAPKLAPHIV 87 Query: 566 VKRVTNR-FNSKSKCNARSYSYTL 634 +K++ + F+++ R+Y Y L Sbjct: 88 LKKLEEKNFHARFDAQKRAYRYLL 111 >UniRef50_Q0F2X2 Cluster: Pseudouridylate synthase; n=1; Mariprofundus ferrooxydans PV-1|Rep: Pseudouridylate synthase - Mariprofundus ferrooxydans PV-1 Length = 267 Score = 32.7 bits (71), Expect = 7.7 Identities = 13/35 (37%), Positives = 20/35 (57%) Frame = +2 Query: 530 NKRLPETIKVFAVKRVTNRFNSKSKCNARSYSYTL 634 N LP+ I+V V+ V F+++ C RSY Y + Sbjct: 91 NSHLPDEIRVVGVRAVAADFHARFACRGRSYRYQI 125 >UniRef50_A7C1F2 Cluster: tRNA pseudouridine synthase A; n=1; Beggiatoa sp. PS|Rep: tRNA pseudouridine synthase A - Beggiatoa sp. PS Length = 272 Score = 32.7 bits (71), Expect = 7.7 Identities = 18/67 (26%), Positives = 31/67 (46%), Gaps = 4/67 (5%) Frame = +2 Query: 446 SSRTDKGVSAAEQVVSLKLPLEVNVEE----INKRLPETIKVFAVKRVTNRFNSKSKCNA 613 + RTD GV A QV+ + ++ + N LP + + + V N F+++ A Sbjct: 47 AGRTDTGVHAIGQVIHADVTVQRSTRSWVLGTNSNLPIDVSMLWAQSVDNNFHARFSAQA 106 Query: 614 RSYSYTL 634 R Y Y + Sbjct: 107 RHYRYII 113 >UniRef50_A2U011 Cluster: Pseudouridylate synthase; n=2; Polaribacter|Rep: Pseudouridylate synthase - Polaribacter dokdonensis MED152 Length = 260 Score = 32.7 bits (71), Expect = 7.7 Identities = 20/65 (30%), Positives = 29/65 (44%), Gaps = 4/65 (6%) Frame = +2 Query: 446 SSRTDKGVSAAEQVVSL----KLPLEVNVEEINKRLPETIKVFAVKRVTNRFNSKSKCNA 613 + RTD VSA + L L +V + E+N LP K + V V +FN + Sbjct: 52 AGRTDAKVSANRYLFQLFTNEVLQQDVFLNELNSNLPADFKAYTVSEVATKFNIINAPKI 111 Query: 614 RSYSY 628 + Y Y Sbjct: 112 KEYHY 116 >UniRef50_Q54I97 Cluster: Pseudouridylate synthase; n=1; Dictyostelium discoideum AX4|Rep: Pseudouridylate synthase - Dictyostelium discoideum AX4 Length = 491 Score = 32.7 bits (71), Expect = 7.7 Identities = 20/78 (25%), Positives = 35/78 (44%) Frame = +2 Query: 263 YERIKRKKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQ 442 +++ ++ +A L Y G ++G Q ++ + + A + Sbjct: 79 FDKCYKRHVAFKLSYVGWPFFGF----AAQDCSEETIENYLIKAFLKTSLIPDIKTANYF 134 Query: 443 RSSRTDKGVSAAEQVVSL 496 +S RTDKGVSA QV+SL Sbjct: 135 KSGRTDKGVSAYGQVISL 152 >UniRef50_A7RKL3 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 639 Score = 32.7 bits (71), Expect = 7.7 Identities = 23/96 (23%), Positives = 43/96 (44%) Frame = +2 Query: 26 VAGKVQEDNCKREKHGNS*KNILAITSARLLSVMEAADVTKDEENKSIDIVPNKLLTRYN 205 + + + KR+ H K S + + E T +++N+ D + K +N Sbjct: 300 ITNRGHNEGNKRKGHNERRKETEPKESEKRNKLTELDGATHNKQNE--DKIDEKNENEHN 357 Query: 206 KRRAHRDWETKPPGEIKKPYERIKRKKMAMLLGYSG 313 K H + ++ G++ K ERI++K+ A G SG Sbjct: 358 KLNEHCEGDSHNEGKMDKENERIEQKEDATKSGASG 393 >UniRef50_Q96KH5 Cluster: HEIL2; n=1; Homo sapiens|Rep: HEIL2 - Homo sapiens (Human) Length = 225 Score = 32.7 bits (71), Expect = 7.7 Identities = 15/46 (32%), Positives = 25/46 (54%) Frame = -3 Query: 173 YRLTYFLHLSLRRQLPLRTASVRLLWLKYFFMNSHAFLVCNYPLVL 36 +RL + +H S L ++ + LWL Y+F S AF + ++ L L Sbjct: 148 FRLNFHVHHSTESTLLKNSSDLPCLWLNYYFNLSAAFYIFDHSLFL 193 >UniRef50_Q8D2P5 Cluster: tRNA pseudouridine synthase A; n=1; Wigglesworthia glossinidia endosymbiont of Glossina brevipalpis|Rep: tRNA pseudouridine synthase A - Wigglesworthia glossinidia brevipalpis Length = 264 Score = 32.7 bits (71), Expect = 7.7 Identities = 30/123 (24%), Positives = 52/123 (42%), Gaps = 5/123 (4%) Frame = +2 Query: 281 KKMAMLLGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFE-NAQNAQFQRSSRT 457 KK+A + Y G Y G Q + +I Y+ F+ + + + + RT Sbjct: 2 KKLAAGISYQGNNYCGWQSQKNIISIQE----------YVELALFKFSGEKIKIYCAGRT 51 Query: 458 DKGVSAAEQVVSLKLPLEVNVEE----INKRLPETIKVFAVKRVTNRFNSKSKCNARSYS 625 D V A QVV ++ + + +N LP I + V +V N F+++ A+ Y Sbjct: 52 DAKVHALLQVVHFYTDIKRSYRQWILGVNSYLPYDISIMWVIKVHNNFHARYSAIAKKYL 111 Query: 626 YTL 634 Y + Sbjct: 112 YLI 114 >UniRef50_P47428 Cluster: tRNA pseudouridine synthase A; n=3; Mycoplasma|Rep: tRNA pseudouridine synthase A - Mycoplasma genitalium Length = 244 Score = 32.7 bits (71), Expect = 7.7 Identities = 17/67 (25%), Positives = 35/67 (52%), Gaps = 4/67 (5%) Frame = +2 Query: 446 SSRTDKGVSAAEQVVSLKLPLEVNVEEINKRLPETIKVFAVKR----VTNRFNSKSKCNA 613 S RTDKGV A Q + + E+N+ + +++ + IK + + V + F+++ + Sbjct: 48 SGRTDKGVHAINQTFHVDINGEINLNLLIRKINQLIKPHCIVKTLVLVNDSFHARFQVKT 107 Query: 614 RSYSYTL 634 + Y Y + Sbjct: 108 KVYEYLI 114 >UniRef50_Q8CY46 Cluster: tRNA pseudouridine synthase A; n=3; Bifidobacterium|Rep: tRNA pseudouridine synthase A - Bifidobacterium longum Length = 303 Score = 32.7 bits (71), Expect = 7.7 Identities = 20/72 (27%), Positives = 32/72 (44%) Frame = +2 Query: 299 LGYSGVEYYGMQRNPGVQTIXXXXXXXXXXXXYITQEDFENAQNAQFQRSSRTDKGVSAA 478 L Y G +YG + P ++T+ + +D A+ + + RTD GV A+ Sbjct: 8 LAYDGGGFYGWAKQPNLRTVQGTIEDALHKVLRVPTDD--AAEPLRLTVAGRTDTGVHAS 65 Query: 479 EQVVSLKLPLEV 514 QV L + EV Sbjct: 66 HQVAHLDVSDEV 77 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 605,115,908 Number of Sequences: 1657284 Number of extensions: 11552404 Number of successful extensions: 35125 Number of sequences better than 10.0: 197 Number of HSP's better than 10.0 without gapping: 33869 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 35005 length of database: 575,637,011 effective HSP length: 97 effective length of database: 414,880,463 effective search space used: 48126133708 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits)
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