Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= bmnc8d11
(706 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI00015B4C48 Cluster: PREDICTED: similar to cullin 1; ... 86 7e-16
UniRef50_Q4TBZ8 Cluster: Chromosome undetermined SCAF7068, whole... 83 9e-15
UniRef50_UPI0000EBC7A7 Cluster: PREDICTED: hypothetical protein ... 79 8e-14
UniRef50_Q6QRN4 Cluster: Cullin 1; n=2; Eutheria|Rep: Cullin 1 -... 79 8e-14
UniRef50_Q13616 Cluster: Cullin-1; n=49; Eukaryota|Rep: Cullin-1... 79 1e-13
UniRef50_Q5C3S3 Cluster: SJCHGC03444 protein; n=1; Schistosoma j... 53 8e-06
UniRef50_Q675W7 Cluster: Cullin; n=1; Oikopleura dioica|Rep: Cul... 52 2e-05
UniRef50_Q17389 Cluster: Cullin-1; n=2; Caenorhabditis|Rep: Cull... 48 2e-04
UniRef50_Q21346 Cluster: Cullin-6; n=1; Caenorhabditis elegans|R... 46 0.001
UniRef50_Q54XF7 Cluster: Putative uncharacterized protein; n=1; ... 40 0.060
UniRef50_O13790 Cluster: Cullin-1; n=2; Schizosaccharomyces pomb... 39 0.14
UniRef50_Q0IEU9 Cluster: Cullin; n=1; Aedes aegypti|Rep: Cullin ... 37 0.55
UniRef50_Q5K745 Cluster: Ubiquitin-protein ligase, putative; n=2... 37 0.55
UniRef50_A3LP00 Cluster: Ubiquitin ligase (Cullin) of SCF involv... 37 0.55
UniRef50_A0KM85 Cluster: Putative membrane protein; n=2; Gammapr... 36 1.3
UniRef50_Q5CUE5 Cluster: Putative uncharacterized protein; n=2; ... 36 1.3
UniRef50_Q2H329 Cluster: Putative uncharacterized protein; n=1; ... 35 2.2
UniRef50_Q7RKH0 Cluster: Sodium/hydrogen exchanger family protei... 34 3.0
UniRef50_Q6C9B4 Cluster: Similar to sp|Q12018 Saccharomyces cere... 34 3.9
UniRef50_UPI0000E49D86 Cluster: PREDICTED: similar to Neuromedin... 33 5.2
UniRef50_A6PUA2 Cluster: Glycoside hydrolase family 2, sugar bin... 33 5.2
>UniRef50_UPI00015B4C48 Cluster: PREDICTED: similar to cullin 1;
n=2; Apocrita|Rep: PREDICTED: similar to cullin 1 -
Nasonia vitripennis
Length = 810
Score = 86.2 bits (204), Expect = 7e-16
Identities = 41/74 (55%), Positives = 53/74 (71%), Gaps = 2/74 (2%)
Frame = +2
Query: 464 STSNANRPQVPLRQKDFDQIWGDLQEGIEQXYKKQYMVKRRYIDLYTHVYNYCTSVHH-- 637
S+ ++N+ L+Q D DQIWGDL+EGIEQ Y +Q M K RYI+LYTHVYNYCTSVH
Sbjct: 42 SSHSSNQGPPGLKQIDLDQIWGDLKEGIEQVYNRQCMSKPRYIELYTHVYNYCTSVHQQI 101
Query: 638 HSAGSSSRVPQNNI 679
+S+ SS+ + I
Sbjct: 102 NSSRQSSKSKKGQI 115
>UniRef50_Q4TBZ8 Cluster: Chromosome undetermined SCAF7068, whole
genome shotgun sequence; n=1; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF7068,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 796
Score = 82.6 bits (195), Expect = 9e-15
Identities = 42/77 (54%), Positives = 50/77 (64%), Gaps = 2/77 (2%)
Frame = +2
Query: 473 NANRPQVP--LRQKDFDQIWGDLQEGIEQXYKKQYMVKRRYIDLYTHVYNYCTSVHHHSA 646
++NR Q P LRQ DQIW DL+ GI+Q Y +Q M K RY++LYTHVYNYCTSVH S
Sbjct: 2 SSNRTQNPHGLRQIGLDQIWDDLRAGIQQVYTRQSMAKSRYMELYTHVYNYCTSVHQSSQ 61
Query: 647 GSSSRVPQNNIGRVSYT 697
G S VP + S T
Sbjct: 62 GRGS-VPSAKPSKKSST 77
>UniRef50_UPI0000EBC7A7 Cluster: PREDICTED: hypothetical protein
isoform 3; n=1; Bos taurus|Rep: PREDICTED: hypothetical
protein isoform 3 - Bos taurus
Length = 776
Score = 79.4 bits (187), Expect = 8e-14
Identities = 36/67 (53%), Positives = 46/67 (68%), Gaps = 2/67 (2%)
Frame = +2
Query: 473 NANRPQVP--LRQKDFDQIWGDLQEGIEQXYKKQYMVKRRYIDLYTHVYNYCTSVHHHSA 646
++NR Q P L+Q DQIW DL+ GI+Q Y +Q M K RY++LYTHVYNYCTSVH +
Sbjct: 2 SSNRSQNPHGLKQIGLDQIWDDLRAGIQQVYTRQSMAKSRYMELYTHVYNYCTSVHQSNQ 61
Query: 647 GSSSRVP 667
+ VP
Sbjct: 62 ARGAGVP 68
>UniRef50_Q6QRN4 Cluster: Cullin 1; n=2; Eutheria|Rep: Cullin 1 -
Bos taurus (Bovine)
Length = 187
Score = 79.4 bits (187), Expect = 8e-14
Identities = 36/67 (53%), Positives = 46/67 (68%), Gaps = 2/67 (2%)
Frame = +2
Query: 473 NANRPQVP--LRQKDFDQIWGDLQEGIEQXYKKQYMVKRRYIDLYTHVYNYCTSVHHHSA 646
++NR Q P L+Q DQIW DL+ GI+Q Y +Q M K RY++LYTHVYNYCTSVH +
Sbjct: 2 SSNRSQNPHGLKQIGLDQIWDDLRAGIQQVYTRQSMAKSRYMELYTHVYNYCTSVHQSNQ 61
Query: 647 GSSSRVP 667
+ VP
Sbjct: 62 ARGAGVP 68
>UniRef50_Q13616 Cluster: Cullin-1; n=49; Eukaryota|Rep: Cullin-1 -
Homo sapiens (Human)
Length = 776
Score = 78.6 bits (185), Expect = 1e-13
Identities = 35/69 (50%), Positives = 46/69 (66%)
Frame = +2
Query: 461 MSTSNANRPQVPLRQKDFDQIWGDLQEGIEQXYKKQYMVKRRYIDLYTHVYNYCTSVHHH 640
MS++ + P L+Q DQIW DL+ GI+Q Y +Q M K RY++LYTHVYNYCTSVH
Sbjct: 1 MSSTRSQNPH-GLKQIGLDQIWDDLRAGIQQVYTRQSMAKSRYMELYTHVYNYCTSVHQS 59
Query: 641 SAGSSSRVP 667
+ + VP
Sbjct: 60 NQARGAGVP 68
>UniRef50_Q5C3S3 Cluster: SJCHGC03444 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC03444 protein - Schistosoma
japonicum (Blood fluke)
Length = 195
Score = 52.8 bits (121), Expect = 8e-06
Identities = 20/47 (42%), Positives = 33/47 (70%)
Frame = +2
Query: 521 IWGDLQEGIEQXYKKQYMVKRRYIDLYTHVYNYCTSVHHHSAGSSSR 661
+W DL+ G + ++ + + ++RY++L+THVYNYCTSV S + SR
Sbjct: 11 VWDDLKNGFDAIFRLETIKRKRYMELHTHVYNYCTSVDPKSHTTPSR 57
>UniRef50_Q675W7 Cluster: Cullin; n=1; Oikopleura dioica|Rep: Cullin
- Oikopleura dioica (Tunicate)
Length = 770
Score = 51.6 bits (118), Expect = 2e-05
Identities = 19/40 (47%), Positives = 29/40 (72%)
Frame = +2
Query: 515 DQIWGDLQEGIEQXYKKQYMVKRRYIDLYTHVYNYCTSVH 634
++ W ++QEG+ + M +RYI+LYTHVYNYCT+V+
Sbjct: 13 ERTWAEVQEGLNNVFFHHGMGHKRYIELYTHVYNYCTAVN 52
>UniRef50_Q17389 Cluster: Cullin-1; n=2; Caenorhabditis|Rep:
Cullin-1 - Caenorhabditis elegans
Length = 780
Score = 48.4 bits (110), Expect = 2e-04
Identities = 17/41 (41%), Positives = 29/41 (70%)
Frame = +2
Query: 509 DFDQIWGDLQEGIEQXYKKQYMVKRRYIDLYTHVYNYCTSV 631
D + +W LQ+G++ Y+++ M + Y+ LYT VY+YCTS+
Sbjct: 12 DSEVVWKKLQDGLDVAYRRENMAPKDYMTLYTSVYDYCTSI 52
>UniRef50_Q21346 Cluster: Cullin-6; n=1; Caenorhabditis elegans|Rep:
Cullin-6 - Caenorhabditis elegans
Length = 729
Score = 46.0 bits (104), Expect = 0.001
Identities = 17/48 (35%), Positives = 32/48 (66%)
Frame = +2
Query: 515 DQIWGDLQEGIEQXYKKQYMVKRRYIDLYTHVYNYCTSVHHHSAGSSS 658
+ +WG LQ+G+ Y++++M K+ Y+ LY VYN CT+ ++ ++S
Sbjct: 4 EAVWGTLQDGLNLLYRREHMSKKYYMMLYDAVYNICTTTTLANSNNNS 51
>UniRef50_Q54XF7 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 750
Score = 39.9 bits (89), Expect = 0.060
Identities = 13/42 (30%), Positives = 29/42 (69%), Gaps = 2/42 (4%)
Frame = +2
Query: 515 DQIWGDLQEGIEQXYK--KQYMVKRRYIDLYTHVYNYCTSVH 634
D++W + ++ E + K+ + ++RY+++YT +YNYC+S +
Sbjct: 8 DELWAECEQTFEDLFLNLKKGLSRKRYMEIYTKIYNYCSSAN 49
>UniRef50_O13790 Cluster: Cullin-1; n=2; Schizosaccharomyces
pombe|Rep: Cullin-1 - Schizosaccharomyces pombe (Fission
yeast)
Length = 767
Score = 38.7 bits (86), Expect = 0.14
Identities = 19/59 (32%), Positives = 36/59 (61%), Gaps = 5/59 (8%)
Frame = +2
Query: 461 MSTSNANRPQVPLRQKDFDQI---WGDLQEGIEQXYKK--QYMVKRRYIDLYTHVYNYC 622
M+T N N +P+ +K +D + W L+ G+ Q +++ + M +Y++LYT ++NYC
Sbjct: 1 MTTLNTNDKDLPIVKK-YDSLNGTWDFLKTGVSQIFERLDEGMTITKYMELYTAIHNYC 58
>UniRef50_Q0IEU9 Cluster: Cullin; n=1; Aedes aegypti|Rep: Cullin -
Aedes aegypti (Yellowfever mosquito)
Length = 757
Score = 36.7 bits (81), Expect = 0.55
Identities = 14/40 (35%), Positives = 25/40 (62%), Gaps = 1/40 (2%)
Frame = +2
Query: 506 KDFDQIWGDLQEGIEQXYKKQYMVK-RRYIDLYTHVYNYC 622
K D+ W L +GI + Y+++ + R++ +T+VYNYC
Sbjct: 23 KQQDETWTKLSDGIGRLYRQEESLNLERFLQYHTYVYNYC 62
>UniRef50_Q5K745 Cluster: Ubiquitin-protein ligase, putative; n=2;
Filobasidiella neoformans|Rep: Ubiquitin-protein ligase,
putative - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 775
Score = 36.7 bits (81), Expect = 0.55
Identities = 19/56 (33%), Positives = 26/56 (46%), Gaps = 2/56 (3%)
Frame = +2
Query: 464 STSNANRPQVPLRQKDFDQIWGDLQEGIEQXYKKQY--MVKRRYIDLYTHVYNYCT 625
S + + Q P + D Q W L G++ + M YI LYT +YNYCT
Sbjct: 9 SWTEPTKAQAPPKDADLKQAWAFLSVGVDHIMTRLSFGMSYSYYILLYTAIYNYCT 64
>UniRef50_A3LP00 Cluster: Ubiquitin ligase (Cullin) of SCF involved
in cell cycle control; n=5; Saccharomycetales|Rep:
Ubiquitin ligase (Cullin) of SCF involved in cell cycle
control - Pichia stipitis (Yeast)
Length = 776
Score = 36.7 bits (81), Expect = 0.55
Identities = 19/67 (28%), Positives = 31/67 (46%), Gaps = 3/67 (4%)
Frame = +2
Query: 509 DFDQIWGDLQEGIE---QXYKKQYMVKRRYIDLYTHVYNYCTSVHHHSAGSSSRVPQNNI 679
D + W +Q G+E Q + + Y++ YT VYNYC + H A ++S ++
Sbjct: 8 DLNATWSFIQPGLEFILGAQGDQGVTPKMYMNCYTAVYNYCVNKSRHGATATSIAASSDS 67
Query: 680 GRVSYTG 700
S G
Sbjct: 68 NSYSLAG 74
>UniRef50_A0KM85 Cluster: Putative membrane protein; n=2;
Gammaproteobacteria|Rep: Putative membrane protein -
Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966
/ NCIB 9240)
Length = 357
Score = 35.5 bits (78), Expect = 1.3
Identities = 16/46 (34%), Positives = 30/46 (65%)
Frame = -3
Query: 413 FCFN*IYSLKNVSIRLLIPLQNAML*SLITSRNHSVGSDYFTLIFI 276
FC +YS++N L++ L ++ LI++ ++VGSDYF+ ++I
Sbjct: 9 FCSLYMYSVQNYKASLIVLLPPFIIYFLISALQYNVGSDYFSYLYI 54
>UniRef50_Q5CUE5 Cluster: Putative uncharacterized protein; n=2;
Cryptosporidium|Rep: Putative uncharacterized protein -
Cryptosporidium parvum Iowa II
Length = 311
Score = 35.5 bits (78), Expect = 1.3
Identities = 13/48 (27%), Positives = 28/48 (58%)
Frame = -2
Query: 399 NIFTEKRIDPITNSVTKCNAIKLNNE*KSQCWQRLFYFNIYIT*LFVF 256
++F + PI N++ N L N+ K++ +QR YF +++ +++F
Sbjct: 195 SLFIVSKYQPIVNNIQIINIFDLANKNKNKLYQRKAYFEVFVVGIYIF 242
>UniRef50_Q2H329 Cluster: Putative uncharacterized protein; n=1;
Chaetomium globosum|Rep: Putative uncharacterized
protein - Chaetomium globosum (Soil fungus)
Length = 724
Score = 34.7 bits (76), Expect = 2.2
Identities = 23/68 (33%), Positives = 34/68 (50%), Gaps = 9/68 (13%)
Frame = +2
Query: 485 PQVPLRQKDFDQIWGDLQEGIEQXYK--KQYMVKRRYIDLYTHVYNYCTS-------VHH 637
P P++ D D W LQ+GI +Q + + Y+ +YT V+N+CTS +
Sbjct: 10 PMQPVKD-DIDTTWTYLQDGITMIMMNLQQGIDLQTYMGIYTAVHNFCTSQKAVGFALQS 68
Query: 638 HSAGSSSR 661
H GSS R
Sbjct: 69 HVIGSSQR 76
>UniRef50_Q7RKH0 Cluster: Sodium/hydrogen exchanger family protein,
putative; n=3; Plasmodium (Vinckeia)|Rep: Sodium/hydrogen
exchanger family protein, putative - Plasmodium yoelii
yoelii
Length = 1688
Score = 34.3 bits (75), Expect = 3.0
Identities = 19/66 (28%), Positives = 34/66 (51%), Gaps = 15/66 (22%)
Frame = +2
Query: 482 RPQVPLRQKDFDQI---------------WGDLQEGIEQXYKKQYMVKRRYIDLYTHVYN 616
RP++ ++ K FDQI +G L++G+ Y+KQ + K R +LY ++N
Sbjct: 1395 RPKIKIQSKQFDQIRRSRSHENYRKNKDKYGKLKDGVFHSYRKQIIRKEREGELYIMIFN 1454
Query: 617 YCTSVH 634
C ++
Sbjct: 1455 TCKELY 1460
>UniRef50_Q6C9B4 Cluster: Similar to sp|Q12018 Saccharomyces
cerevisiae YDL132w CDC53 controls G1/S transition; n=1;
Yarrowia lipolytica|Rep: Similar to sp|Q12018
Saccharomyces cerevisiae YDL132w CDC53 controls G1/S
transition - Yarrowia lipolytica (Candida lipolytica)
Length = 788
Score = 33.9 bits (74), Expect = 3.9
Identities = 16/55 (29%), Positives = 29/55 (52%), Gaps = 5/55 (9%)
Frame = +2
Query: 479 NRPQVPLRQKDFDQIWGDLQEGIEQXYKKQY-----MVKRRYIDLYTHVYNYCTS 628
N P +P R D D W +++G+ Q + + + Y++LY+ ++NYC S
Sbjct: 3 NTPPLP-RADDIDATWKYIEDGVGQVLRDDLAHGAGLSSQMYMNLYSAIHNYCVS 56
>UniRef50_UPI0000E49D86 Cluster: PREDICTED: similar to Neuromedin B
receptor; n=2; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to Neuromedin B receptor -
Strongylocentrotus purpuratus
Length = 385
Score = 33.5 bits (73), Expect = 5.2
Identities = 20/57 (35%), Positives = 30/57 (52%), Gaps = 2/57 (3%)
Frame = -3
Query: 251 RAETLRFGFLVRDCLSVVAPVFTLSSTTLHFFMYLMRYD*ACFIIPRFTI--TIHQI 87
R+ +R +V C+ VVA + S L F Y M+ CFI+P FT+ IH++
Sbjct: 156 RSPVVRRTCVVAVCIWVVAVCLGIPSMFLAFLSYEMKPYVLCFILPHFTLQARIHEV 212
>UniRef50_A6PUA2 Cluster: Glycoside hydrolase family 2, sugar
binding; n=1; Victivallis vadensis ATCC BAA-548|Rep:
Glycoside hydrolase family 2, sugar binding -
Victivallis vadensis ATCC BAA-548
Length = 215
Score = 33.5 bits (73), Expect = 5.2
Identities = 16/40 (40%), Positives = 23/40 (57%)
Frame = +1
Query: 484 TPSAAAAKGL*SDMGRSSRGNRTXLQKTVHGQETIHRSVY 603
TP AAAKG+ +++G + +RT L T G H+ VY
Sbjct: 111 TPEQAAAKGMRAELGHINTADRTFLNGTQIGAADEHKRVY 150
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 640,236,283
Number of Sequences: 1657284
Number of extensions: 11867506
Number of successful extensions: 28570
Number of sequences better than 10.0: 21
Number of HSP's better than 10.0 without gapping: 27540
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 28560
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 56198352344
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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