Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= bmnc3d18
(508 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q9NXA8 Cluster: NAD-dependent deacetylase sirtuin-5; n=... 159 4e-38
UniRef50_A7RMK8 Cluster: Predicted protein; n=5; Eumetazoa|Rep: ... 124 9e-28
UniRef50_UPI0000D578DC Cluster: PREDICTED: similar to sirtuin 5 ... 100 2e-20
UniRef50_Q8U1Q1 Cluster: NAD-dependent deacetylase; n=19; cellul... 91 2e-17
UniRef50_Q8ZT00 Cluster: NAD-dependent deacetylase 2; n=2; cellu... 90 3e-17
UniRef50_Q8Y015 Cluster: NAD-dependent deacetylase; n=11; Bacter... 84 2e-15
UniRef50_Q9RYD4 Cluster: NAD-dependent deacetylase; n=4; Deinoco... 84 2e-15
UniRef50_Q9CBW6 Cluster: NAD-dependent deacetylase; n=14; Mycoba... 83 4e-15
UniRef50_Q3E2I1 Cluster: Silent information regulator protein Si... 81 1e-14
UniRef50_Q0LFI4 Cluster: Silent information regulator protein Si... 79 8e-14
UniRef50_A5WD15 Cluster: Silent information regulator protein Si... 78 1e-13
UniRef50_A2QWZ2 Cluster: Function: human SIRT5 belongs to the Si... 75 9e-13
UniRef50_Q4APN6 Cluster: Silent information regulator protein Si... 71 2e-11
UniRef50_A1CTI6 Cluster: SIR2 family histone deacetylase, putati... 70 3e-11
UniRef50_Q607X6 Cluster: NAD-dependent deacetylase; n=1; Methylo... 70 3e-11
UniRef50_Q9I4L0 Cluster: NAD-dependent deacetylase 1; n=10; Bact... 69 5e-11
UniRef50_Q0LN22 Cluster: Silent information regulator protein Si... 69 6e-11
UniRef50_A7DQD6 Cluster: Silent information regulator protein Si... 69 8e-11
UniRef50_Q21KQ1 Cluster: Silent information regulator protein Si... 68 1e-10
UniRef50_A1FG80 Cluster: Silent information regulator protein Si... 68 1e-10
UniRef50_Q88BY5 Cluster: NAD-dependent deacetylase; n=9; Bacteri... 66 4e-10
UniRef50_A4RCT8 Cluster: Putative uncharacterized protein; n=3; ... 65 8e-10
UniRef50_A6SP88 Cluster: Putative uncharacterized protein; n=2; ... 64 2e-09
UniRef50_A7SK95 Cluster: Predicted protein; n=1; Nematostella ve... 64 2e-09
UniRef50_Q7S223 Cluster: Putative uncharacterized protein NCU059... 64 2e-09
UniRef50_A3LRA1 Cluster: Transcriptional regulatory protein; n=2... 64 2e-09
UniRef50_Q6C8C7 Cluster: Similar to DEHA0C01507g Debaryomyces ha... 63 3e-09
UniRef50_Q3S8X8 Cluster: IS-Sir2; n=3; Pseudomonas syringae grou... 63 4e-09
UniRef50_Q2LSF2 Cluster: Sir2 family of NAD+-dependent deacetyla... 62 5e-09
UniRef50_Q6BVM7 Cluster: Similar to CA4170|IPF7784 Candida albic... 62 7e-09
UniRef50_Q8F3Z6 Cluster: NAD-dependent deacetylase; n=4; Leptosp... 61 2e-08
UniRef50_Q6MJJ2 Cluster: NAD-dependent deacetylase; n=5; Proteob... 61 2e-08
UniRef50_A0LG97 Cluster: Silent information regulator protein Si... 60 2e-08
UniRef50_Q8FRV5 Cluster: NAD-dependent deacetylase 2; n=9; Coryn... 60 2e-08
UniRef50_A5USR3 Cluster: Silent information regulator protein Si... 60 4e-08
UniRef50_Q67KQ0 Cluster: NAD-dependent deacetylase; n=1; Symbiob... 59 5e-08
UniRef50_A5DW75 Cluster: Putative uncharacterized protein; n=1; ... 59 7e-08
UniRef50_Q89EA6 Cluster: NAD-dependent deacetylase 2; n=9; Prote... 58 9e-08
UniRef50_A7B9E8 Cluster: Putative uncharacterized protein; n=1; ... 58 1e-07
UniRef50_A2DZ01 Cluster: Transcriptional regulator, Sir2 family ... 57 2e-07
UniRef50_Q73KE1 Cluster: NAD-dependent deacetylase; n=1; Trepone... 57 2e-07
UniRef50_Q1D737 Cluster: NAD-dependent deacetylase; n=1; Myxococ... 57 3e-07
UniRef50_A4J646 Cluster: Silent information regulator protein Si... 57 3e-07
UniRef50_Q7WLE5 Cluster: NAD-dependent deacetylase; n=47; Bacter... 57 3e-07
UniRef50_Q5YR82 Cluster: Putative Sir2 family regulator; n=1; No... 56 5e-07
UniRef50_Q8ZFR1 Cluster: NAD-dependent deacetylase; n=149; cellu... 56 5e-07
UniRef50_Q8CJM9 Cluster: NAD-dependent deacetylase 2; n=3; Actin... 56 5e-07
UniRef50_A5K7T7 Cluster: NAD-dependent deacetylase, putative; n=... 55 8e-07
UniRef50_Q75DM1 Cluster: ABL004Wp; n=1; Eremothecium gossypii|Re... 55 8e-07
UniRef50_UPI00015B4FA0 Cluster: PREDICTED: similar to chromatin ... 55 1e-06
UniRef50_Q8ZU41 Cluster: NAD-dependent deacetylase 1; n=3; Pyrob... 55 1e-06
UniRef50_A6PTK3 Cluster: Silent information regulator protein Si... 54 1e-06
UniRef50_Q0LIC7 Cluster: Silent information regulator protein Si... 54 2e-06
UniRef50_A6P1S7 Cluster: Putative uncharacterized protein; n=2; ... 54 2e-06
UniRef50_A0NQ49 Cluster: Silent information regulator protein Si... 54 2e-06
UniRef50_UPI0000499DEA Cluster: Sir2 family transcriptional regu... 53 3e-06
UniRef50_A6FYM4 Cluster: Sir2 family protein; n=1; Plesiocystis ... 53 3e-06
UniRef50_UPI0000F1D51E Cluster: PREDICTED: hypothetical protein;... 53 4e-06
UniRef50_A1I9S7 Cluster: NAD-dependent deacetylase; n=1; Candida... 53 4e-06
UniRef50_UPI000049971A Cluster: Sir2 family transcriptional regu... 52 6e-06
UniRef50_UPI00006CB0CC Cluster: transcriptional regulator, Sir2 ... 52 7e-06
UniRef50_A6DC77 Cluster: Silent information regulator protein Si... 52 7e-06
UniRef50_Q9WYW0 Cluster: NAD-dependent deacetylase; n=4; Thermot... 52 7e-06
UniRef50_Q2YZT2 Cluster: Putative uncharacterized protein; n=1; ... 52 1e-05
UniRef50_UPI000049979A Cluster: Sir2 family transcriptional regu... 51 1e-05
UniRef50_Q011Q8 Cluster: NAD-dependent deacetylase SIRT2; n=2; O... 51 2e-05
UniRef50_Q12Y78 Cluster: Silent information regulator protein Si... 51 2e-05
UniRef50_Q54QE6 Cluster: Zn finger-containing protein; n=5; Euka... 50 3e-05
UniRef50_A0PU12 Cluster: Sir2-like regulatory protein; n=1; Myco... 50 4e-05
UniRef50_Q54LF0 Cluster: Ankyrin repeat-containing protein; n=1;... 50 4e-05
UniRef50_Q8R216 Cluster: NAD-dependent deacetylase sirtuin-4; n=... 50 4e-05
UniRef50_Q97MB4 Cluster: NAD-dependent deacetylase; n=7; Bacteri... 50 4e-05
UniRef50_A7HL19 Cluster: Silent information regulator protein Si... 49 5e-05
UniRef50_A6LP94 Cluster: Silent information regulator protein Si... 49 5e-05
UniRef50_A4QUX8 Cluster: Putative uncharacterized protein; n=1; ... 49 5e-05
UniRef50_UPI0000519F58 Cluster: PREDICTED: similar to Sirt4 CG31... 49 7e-05
UniRef50_A1ZZG3 Cluster: NAD-dependent deacetylase; n=35; Bacter... 48 1e-04
UniRef50_A1HU63 Cluster: Silent information regulator protein Si... 48 1e-04
UniRef50_Q9Y6E7 Cluster: NAD-dependent deacetylase sirtuin-4; n=... 48 1e-04
UniRef50_Q5L014 Cluster: NAD-dependent deacetylase 1; n=7; Bacil... 48 1e-04
UniRef50_Q974M6 Cluster: NAD-dependent deacetylase; n=8; Thermop... 48 2e-04
UniRef50_Q8A3H9 Cluster: NAD-dependent deacetylase; n=3; Bactero... 48 2e-04
UniRef50_Q9USN7 Cluster: Sir2 family histone deacetylase Hst2; n... 47 2e-04
UniRef50_A1DG07 Cluster: SIR2 family histone deacetylase, putati... 47 2e-04
UniRef50_Q8REC3 Cluster: NAD-dependent deacetylase; n=3; Fusobac... 47 2e-04
UniRef50_UPI000023DCB3 Cluster: hypothetical protein FG05505.1; ... 47 3e-04
UniRef50_A3JEV2 Cluster: NAD-dependent deacetylase; n=2; Marinob... 47 3e-04
UniRef50_Q7ZVK3 Cluster: NAD-dependent deacetylase sirtuin-2; n=... 47 3e-04
UniRef50_Q3A6W7 Cluster: NAD-dependent protein deacetylases, SIR... 46 4e-04
UniRef50_Q5V4Q5 Cluster: NAD-dependent deacetylase; n=2; Halobac... 46 4e-04
UniRef50_Q882K4 Cluster: NAD-dependent deacetylase 3; n=5; Pseud... 46 4e-04
UniRef50_Q0R0H8 Cluster: Sir2-like protein; n=1; Naegleria sp. T... 46 5e-04
UniRef50_A1A3R7 Cluster: Sir2-type regulatory protein; n=2; Bifi... 46 7e-04
UniRef50_Q1RPU9 Cluster: Zinc finger protein; n=1; Ciona intesti... 46 7e-04
UniRef50_A4R235 Cluster: Putative uncharacterized protein; n=1; ... 46 7e-04
UniRef50_Q8G465 Cluster: Sir2-type regulatory protein; n=2; Bifi... 45 9e-04
UniRef50_Q1QTH0 Cluster: Silent information regulator protein Si... 45 9e-04
UniRef50_Q4P3S4 Cluster: Putative uncharacterized protein; n=1; ... 45 9e-04
UniRef50_UPI0000E49AD8 Cluster: PREDICTED: similar to NAD-depend... 45 0.001
UniRef50_Q54P49 Cluster: Zn finger-containing protein; n=1; Dict... 45 0.001
UniRef50_Q25337 Cluster: NAD-dependent deacetylase SIR2 homolog;... 45 0.001
UniRef50_Q1YSP9 Cluster: NAD-dependent deacetylase; n=1; gamma p... 44 0.002
UniRef50_Q4WFZ3 Cluster: SIR2 family histone deacetylase, putati... 44 0.002
UniRef50_Q8CNF4 Cluster: NAD-dependent deacetylase; n=17; Staphy... 44 0.002
UniRef50_A4M603 Cluster: Silent information regulator protein Si... 44 0.002
UniRef50_A3WK56 Cluster: SIR2-like regulatory protein, NAD-depen... 44 0.002
UniRef50_Q1D9X2 Cluster: Sir2 family protein; n=1; Myxococcus xa... 44 0.003
UniRef50_A1HLU5 Cluster: Silent information regulator protein Si... 44 0.003
UniRef50_A2F8E1 Cluster: Transcriptional regulator, Sir2 family ... 44 0.003
UniRef50_A2QFF9 Cluster: Complex: Sir2p is one of four Silent In... 44 0.003
UniRef50_Q899G3 Cluster: NAD-dependent deacetylase; n=19; cellul... 44 0.003
UniRef50_Q0AY57 Cluster: Regulatory protein, sir2 family; n=1; S... 43 0.003
UniRef50_A2F9H1 Cluster: Transcriptional regulator, Sir2 family ... 43 0.003
UniRef50_Q89LY4 Cluster: NAD-dependent deacetylase 1; n=12; Prot... 43 0.003
UniRef50_A7H7B6 Cluster: Silent information regulator protein Si... 43 0.005
UniRef50_A3ZMQ7 Cluster: Sir2 family, possible ADP ribosyltransf... 43 0.005
UniRef50_Q6C8V5 Cluster: Similar to tr|Q9FY91 Arabidopsis thalia... 43 0.005
UniRef50_A1CD03 Cluster: SIR2 family histone deacetylase, putati... 43 0.005
UniRef50_A6G0H3 Cluster: Silent information regulator protein Si... 42 0.006
UniRef50_A2DP91 Cluster: Transcriptional regulator, Sir2 family ... 42 0.006
UniRef50_Q7SCL4 Cluster: Putative uncharacterized protein NCU005... 42 0.006
UniRef50_A2GAR7 Cluster: Transcriptional regulator, Sir2 family ... 42 0.008
UniRef50_O94066 Cluster: Transcription regulatory protein; n=6; ... 42 0.008
UniRef50_Q046W9 Cluster: NAD-dependent protein deacetylase, SIR2... 42 0.011
UniRef50_A0Z2E4 Cluster: NAD-dependent deacetylase; n=1; marine ... 42 0.011
UniRef50_Q4QB33 Cluster: Sir2-family protein-like protein; n=4; ... 42 0.011
UniRef50_Q4WET3 Cluster: SIR2 family histone deacetylase, putati... 42 0.011
UniRef50_A7EC18 Cluster: Putative uncharacterized protein; n=1; ... 42 0.011
UniRef50_A6RXY5 Cluster: Putative uncharacterized protein; n=2; ... 41 0.014
UniRef50_Q96EB6 Cluster: NAD-dependent deacetylase sirtuin-1; n=... 41 0.014
UniRef50_UPI0000D55B5A Cluster: PREDICTED: similar to CG5216-PA;... 41 0.019
UniRef50_A5UYK2 Cluster: Silent information regulator protein Si... 41 0.019
UniRef50_Q7JMD3 Cluster: Putative uncharacterized protein sir-2.... 41 0.019
UniRef50_Q4DP02 Cluster: Silent information regulator 2, putativ... 41 0.019
UniRef50_Q298C7 Cluster: GA18650-PA; n=1; Drosophila pseudoobscu... 41 0.019
UniRef50_A2QUR5 Cluster: Remark: the H. sapiens SIRT4 belongs to... 41 0.019
UniRef50_Q3V7G9 Cluster: Putative cobalamin biosynthetic protein... 40 0.024
UniRef50_Q9FY91 Cluster: SIR2-family protein; n=12; Magnoliophyt... 40 0.024
UniRef50_A7RLD5 Cluster: Predicted protein; n=1; Nematostella ve... 40 0.024
UniRef50_Q5KDE0 Cluster: NAD-dependent histone deacetylase, puta... 40 0.024
UniRef50_O07595 Cluster: NAD-dependent deacetylase; n=3; Bacillu... 40 0.024
UniRef50_Q9RL35 Cluster: NAD-dependent deacetylase 1; n=8; Actin... 40 0.024
UniRef50_A6TNA0 Cluster: Silent information regulator protein Si... 40 0.032
UniRef50_A6XDL2 Cluster: Sirtuin 1; n=2; Schistosoma|Rep: Sirtui... 40 0.032
UniRef50_Q21921 Cluster: NAD-dependent deacetylase SIR2 homolog;... 40 0.032
UniRef50_A1ZHW6 Cluster: NAD-dependent deacetylase; n=2; Microsc... 40 0.043
UniRef50_Q8IRR5 Cluster: CG3187-PC, isoform C; n=4; Diptera|Rep:... 40 0.043
UniRef50_A0DQW0 Cluster: Chromosome undetermined scaffold_6, who... 40 0.043
UniRef50_O25849 Cluster: NAD-dependent deacetylase; n=11; Bacter... 40 0.043
UniRef50_Q8IXJ6 Cluster: NAD-dependent deacetylase sirtuin-2; n=... 39 0.057
UniRef50_Q839C6 Cluster: NAD-dependent deacetylase; n=14; Bacill... 39 0.057
UniRef50_Q8R984 Cluster: NAD-dependent deacetylase 2; n=1; Therm... 39 0.057
UniRef50_UPI000050FCF4 Cluster: COG0846: NAD-dependent protein d... 39 0.075
UniRef50_Q22KA8 Cluster: Transcriptional regulator, Sir2 family ... 39 0.075
UniRef50_Q2U9Y7 Cluster: Sirtuin 4 and related class II sirtuins... 38 0.099
UniRef50_A3LN35 Cluster: NAD-dependent histone deacetylase SIR2;... 38 0.099
UniRef50_UPI00006CA40C Cluster: transcriptional regulator, Sir2 ... 38 0.13
UniRef50_A1ZPG8 Cluster: NAD-dependent deacetylase; n=1; Microsc... 38 0.13
UniRef50_Q480E0 Cluster: Putative membrane protein; n=1; Colwell... 38 0.17
UniRef50_UPI000051AA14 Cluster: PREDICTED: similar to NAD-depend... 37 0.23
UniRef50_A0JXS0 Cluster: Silent information regulator protein Si... 37 0.23
UniRef50_Q3F1F4 Cluster: SIR2 family protein; n=1; Bacillus thur... 37 0.30
UniRef50_A4A8B4 Cluster: Silent information regulator protein Si... 37 0.30
UniRef50_UPI00015B57C0 Cluster: PREDICTED: similar to GA18743-PA... 36 0.40
UniRef50_Q9FE17 Cluster: Sir2-like protein; n=9; Magnoliophyta|R... 36 0.53
UniRef50_A2DZ29 Cluster: Transcriptional regulator, Sir2 family ... 36 0.53
UniRef50_Q885X7 Cluster: NAD-dependent deacetylase 2; n=4; Pseud... 36 0.53
UniRef50_Q6AF12 Cluster: Regulatory protein, Sir2 family; n=2; A... 36 0.70
UniRef50_Q7QZ36 Cluster: GLP_464_21655_23334; n=1; Giardia lambl... 36 0.70
UniRef50_Q1RPU3 Cluster: Zinc finger protein; n=1; Ciona intesti... 36 0.70
UniRef50_A2DKF0 Cluster: Transcriptional regulator, Sir2 family ... 36 0.70
UniRef50_Q7S6G9 Cluster: Putative uncharacterized protein NCU047... 35 0.92
UniRef50_Q4P1X1 Cluster: Putative uncharacterized protein; n=1; ... 35 0.92
UniRef50_A4QX96 Cluster: Putative uncharacterized protein; n=2; ... 35 0.92
UniRef50_Q7QZ37 Cluster: GLP_464_19573_21615; n=1; Giardia lambl... 35 1.2
UniRef50_Q6C219 Cluster: Yarrowia lipolytica chromosome F of str... 35 1.2
UniRef50_Q03ZB1 Cluster: NAD-dependent protein deacetylase, SIR2... 34 1.6
UniRef50_Q1RL71 Cluster: Zinc finger protein; n=2; Ciona intesti... 34 1.6
UniRef50_Q88ZA0 Cluster: NAD-dependent deacetylase; n=4; Lactoba... 34 1.6
UniRef50_UPI00004992B3 Cluster: conserved hypothetical protein; ... 34 2.1
UniRef50_A5AF92 Cluster: Putative uncharacterized protein; n=1; ... 34 2.1
UniRef50_O96505 Cluster: SIR2; n=4; Sophophora|Rep: SIR2 - Droso... 34 2.1
UniRef50_A0C6J0 Cluster: Chromosome undetermined scaffold_152, w... 34 2.1
UniRef50_Q6FKU1 Cluster: Similar to sp|P53686 Saccharomyces cere... 34 2.1
UniRef50_Q5AQ47 Cluster: Potential Sir2 family histone deacetyla... 34 2.1
UniRef50_A5DNV7 Cluster: Putative uncharacterized protein; n=1; ... 34 2.1
UniRef50_P06700 Cluster: NAD-dependent histone deacetylase SIR2;... 34 2.1
UniRef50_Q4V944 Cluster: Mdm4 protein; n=5; Clupeocephala|Rep: M... 33 2.8
UniRef50_Q9I4E1 Cluster: NAD-dependent deacetylase 2; n=6; Pseud... 33 2.8
UniRef50_Q5P3W1 Cluster: NAD-dependent deacetylase 2; n=4; Prote... 33 3.7
UniRef50_A7SX90 Cluster: Predicted protein; n=3; Eumetazoa|Rep: ... 33 3.7
UniRef50_A7EMW8 Cluster: Putative uncharacterized protein; n=1; ... 33 3.7
UniRef50_A6SFT5 Cluster: Putative uncharacterized protein; n=1; ... 33 3.7
UniRef50_Q81VZ1 Cluster: Bifunctional protein glmU [Includes: UD... 33 3.7
UniRef50_Q8X0B5 Cluster: Putative uncharacterized protein B14D6.... 33 4.9
UniRef50_Q874C2 Cluster: Cation-transporting ATPase; n=1; Tramet... 33 4.9
UniRef50_A7TQE2 Cluster: Putative uncharacterized protein; n=1; ... 33 4.9
UniRef50_Q2P6K4 Cluster: Putative uncharacterized protein XOO106... 32 6.5
UniRef50_Q7RDB7 Cluster: Putative uncharacterized protein PY0550... 32 6.5
UniRef50_Q7PS76 Cluster: ENSANGP00000025231; n=1; Anopheles gamb... 32 6.5
UniRef50_A5DSX8 Cluster: NAD-dependent histone deacetylase SIR2;... 32 6.5
UniRef50_A5DJ74 Cluster: Putative uncharacterized protein; n=1; ... 32 6.5
UniRef50_Q8N6T7 Cluster: Mono-ADP-ribosyltransferase sirtuin-6; ... 32 6.5
UniRef50_O59923 Cluster: NAD-dependent histone deacetylase SIR2;... 32 6.5
UniRef50_Q8FUC8 Cluster: NAD-dependent deacetylase 1; n=6; Coryn... 32 6.5
UniRef50_A2F8N6 Cluster: Transcriptional regulator, Sir2 family ... 32 8.6
UniRef50_Q750H1 Cluster: AGL018Cp; n=1; Eremothecium gossypii|Re... 32 8.6
UniRef50_A3GG83 Cluster: DASH complex subunit ask1; n=2; Pichia ... 32 8.6
UniRef50_A0B7T8 Cluster: Tungsten formylmethanofuran dehydrogena... 32 8.6
UniRef50_Q9NRC8 Cluster: NAD-dependent deacetylase sirtuin-7; n=... 32 8.6
>UniRef50_Q9NXA8 Cluster: NAD-dependent deacetylase sirtuin-5; n=28;
Coelomata|Rep: NAD-dependent deacetylase sirtuin-5 -
Homo sapiens (Human)
Length = 310
Score = 159 bits (385), Expect = 4e-38
Identities = 70/103 (67%), Positives = 84/103 (81%)
Frame = +2
Query: 2 PVKLLPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAM 181
PV+ LP C++A CG LLRPH+VWFGE+L+ ILE + ++ CD+CLVVGTSSVVYPAAM
Sbjct: 200 PVEKLPRCEEAGCGGLLRPHVVWFGENLDPAILEEVDRELAHCDLCLVVGTSSVVYPAAM 259
Query: 182 FAPQAASRGAIVAEFNIEPTPATPDFHFYFEGPCGTTLPQALA 310
FAPQ A+RG VAEFN E TPAT F F+F+GPCGTTLP+ALA
Sbjct: 260 FAPQVAARGVPVAEFNTETTPATNRFRFHFQGPCGTTLPEALA 302
>UniRef50_A7RMK8 Cluster: Predicted protein; n=5; Eumetazoa|Rep:
Predicted protein - Nematostella vectensis
Length = 273
Score = 124 bits (300), Expect = 9e-28
Identities = 55/102 (53%), Positives = 68/102 (66%)
Frame = +2
Query: 2 PVKLLPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAM 181
P+ LP C + C AL+RPH+VWFGE+L+ +L+ E + CD C +VGTSSVVYPAA
Sbjct: 168 PLTELPRCVRPECDALVRPHVVWFGEALDPVVLQQIEKVLGECDFCFIVGTSSVVYPAAG 227
Query: 182 FAPQAASRGAIVAEFNIEPTPATPDFHFYFEGPCGTTLPQAL 307
FAP A RG VAEFN+E T T F F+F+G G TLP L
Sbjct: 228 FAPMLAQRGVPVAEFNMEETSCTGQFSFHFQGKAGVTLPPIL 269
>UniRef50_UPI0000D578DC Cluster: PREDICTED: similar to sirtuin 5
(silent mating type information regulation 2 homolog) 5;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
sirtuin 5 (silent mating type information regulation 2
homolog) 5 - Tribolium castaneum
Length = 254
Score = 100 bits (240), Expect = 2e-20
Identities = 44/77 (57%), Positives = 59/77 (76%)
Frame = +2
Query: 2 PVKLLPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAM 181
P++ LP C + C AL+RP+IVWFGE+L+ D+L+ + + +CD+CLV+GTSSVVYPAAM
Sbjct: 170 PLEELPKCSE--CQALVRPYIVWFGENLDPDVLDRSRQLIESCDLCLVIGTSSVVYPAAM 227
Query: 182 FAPQAASRGAIVAEFNI 232
FAP RG VAEFN+
Sbjct: 228 FAPTVVERGKPVAEFNL 244
>UniRef50_Q8U1Q1 Cluster: NAD-dependent deacetylase; n=19; cellular
organisms|Rep: NAD-dependent deacetylase - Pyrococcus
furiosus
Length = 250
Score = 90.6 bits (215), Expect = 2e-17
Identities = 47/100 (47%), Positives = 55/100 (55%)
Frame = +2
Query: 14 LPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQ 193
LP C K CG+LLRP +VWFGE+L L A DV LVVGTS VVYPAA
Sbjct: 147 LPRCPK--CGSLLRPDVVWFGEALPEKELTTAFSLAKKADVVLVVGTSGVVYPAAYIPYI 204
Query: 194 AASRGAIVAEFNIEPTPATPDFHFYFEGPCGTTLPQALAD 313
G IV E NIEP+ TP F+ G G LP+ + +
Sbjct: 205 VKESGGIVVEINIEPSAITPIADFFLRGKAGEVLPKLVEE 244
>UniRef50_Q8ZT00 Cluster: NAD-dependent deacetylase 2; n=2; cellular
organisms|Rep: NAD-dependent deacetylase 2 - Pyrobaculum
aerophilum
Length = 249
Score = 89.8 bits (213), Expect = 3e-17
Identities = 46/99 (46%), Positives = 56/99 (56%)
Frame = +2
Query: 17 PHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQA 196
P C+K CG LLRP +VWFGE L + AA S DV LVVGTS VVYPAA A
Sbjct: 140 PLCRK--CGGLLRPDVVWFGEPLPQEAWRAAVELASVSDVLLVVGTSGVVYPAAYIPRIA 197
Query: 197 ASRGAIVAEFNIEPTPATPDFHFYFEGPCGTTLPQALAD 313
GA V E N+EP+ TP + +G G LP+ + +
Sbjct: 198 KEAGARVVEINVEPSAITPIADVFIQGRAGEVLPRLVEE 236
>UniRef50_Q8Y015 Cluster: NAD-dependent deacetylase; n=11;
Bacteria|Rep: NAD-dependent deacetylase - Ralstonia
solanacearum (Pseudomonas solanacearum)
Length = 246
Score = 84.2 bits (199), Expect = 2e-15
Identities = 47/98 (47%), Positives = 52/98 (53%)
Frame = +2
Query: 17 PHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQA 196
P C A CGA+LRP +VWFGE L AE A +TCDVCLVVGTS +VYPAA A
Sbjct: 151 PRC--AACGAMLRPGVVWFGERLPVVANYRAEEAANTCDVCLVVGTSGMVYPAAGLPGLA 208
Query: 197 ASRGAIVAEFNIEPTPATPDFHFYFEGPCGTTLPQALA 310
GA V N EP+ P G LP LA
Sbjct: 209 KDHGARVIVVNPEPSVLDETADLVIHQPAGVCLPAMLA 246
>UniRef50_Q9RYD4 Cluster: NAD-dependent deacetylase; n=4;
Deinococci|Rep: NAD-dependent deacetylase - Deinococcus
radiodurans
Length = 246
Score = 83.8 bits (198), Expect = 2e-15
Identities = 44/91 (48%), Positives = 51/91 (56%)
Frame = +2
Query: 41 GALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQAASRGAIVA 220
G +RPHIVWFGE L D L+AA+ A + +V LV+GTSSVVYPAA A + RG V
Sbjct: 155 GQRMRPHIVWFGEYLPVDALDAAQRAFAGAEVALVIGTSSVVYPAAGLAAETLRRGGAVI 214
Query: 221 EFNIEPTPATPDFHFYFEGPCGTTLPQALAD 313
E N E T TPD F L L D
Sbjct: 215 EINPEATDLTPDATFSLRESASRGLELLLED 245
>UniRef50_Q9CBW6 Cluster: NAD-dependent deacetylase; n=14;
Mycobacterium|Rep: NAD-dependent deacetylase -
Mycobacterium leprae
Length = 237
Score = 83.0 bits (196), Expect = 4e-15
Identities = 43/91 (47%), Positives = 51/91 (56%)
Frame = +2
Query: 35 HCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQAASRGAI 214
+CG L+RP IVWFGE L + A A T DV +VVGTS++VYPAA A SRGA+
Sbjct: 139 YCGGLIRPAIVWFGEPLPDEPWRRAVEATETTDVMVVVGTSAIVYPAAGLPELALSRGAV 198
Query: 215 VAEFNIEPTPATPDFHFYFEGPCGTTLPQAL 307
V E N EPTP T + LP L
Sbjct: 199 VIEVNPEPTPLTKNATISIRETASQALPGLL 229
>UniRef50_Q3E2I1 Cluster: Silent information regulator protein Sir2;
n=7; Bacteria|Rep: Silent information regulator protein
Sir2 - Chloroflexus aurantiacus J-10-fl
Length = 254
Score = 81.0 bits (191), Expect = 1e-14
Identities = 47/99 (47%), Positives = 53/99 (53%)
Frame = +2
Query: 14 LPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQ 193
LP C +CGALLRP +VWFGE L LEAA A CDV +GTS VV PAA
Sbjct: 147 LPQCP--NCGALLRPDVVWFGEYLPPGALEAAYAATLDCDVFCSIGTSGVVEPAASLPRI 204
Query: 194 AASRGAIVAEFNIEPTPATPDFHFYFEGPCGTTLPQALA 310
A SRGA V N+E T F G G LP+ +A
Sbjct: 205 ALSRGATVLILNLEQTTTARSPLFTVYGKAGEVLPRLVA 243
>UniRef50_Q0LFI4 Cluster: Silent information regulator protein Sir2;
n=1; Herpetosiphon aurantiacus ATCC 23779|Rep: Silent
information regulator protein Sir2 - Herpetosiphon
aurantiacus ATCC 23779
Length = 171
Score = 78.6 bits (185), Expect = 8e-14
Identities = 43/99 (43%), Positives = 53/99 (53%)
Frame = +2
Query: 14 LPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQ 193
LP C C A LRP +VWFGE L+ ++AAE A TCDV L +GTS VV PAA F
Sbjct: 70 LPFCSV--CAAPLRPDVVWFGERLDLAKIQAAELASQTCDVFLAIGTSGVVAPAATFPMT 127
Query: 194 AASRGAIVAEFNIEPTPATPDFHFYFEGPCGTTLPQALA 310
A + A + + N+E TP + G LP LA
Sbjct: 128 ARAHRARLIDLNLEDTPLSRHARHRLRGTAAQLLPALLA 166
>UniRef50_A5WD15 Cluster: Silent information regulator protein Sir2;
n=2; Psychrobacter|Rep: Silent information regulator
protein Sir2 - Psychrobacter sp. PRwf-1
Length = 249
Score = 77.8 bits (183), Expect = 1e-13
Identities = 42/91 (46%), Positives = 50/91 (54%)
Frame = +2
Query: 38 CGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQAASRGAIV 217
CG +RP IVWFGE L + AE A CDV + +GTSS+VYPAA A A GA V
Sbjct: 155 CGGHIRPDIVWFGEMLPQGAWQYAEEAAVHCDVFISIGTSSLVYPAAGLAQLAKQTGAKV 214
Query: 218 AEFNIEPTPATPDFHFYFEGPCGTTLPQALA 310
E N+ PT +P G G LP+ LA
Sbjct: 215 IEINLNPT-QSPLVDVVLAGQAGEILPRILA 244
>UniRef50_A2QWZ2 Cluster: Function: human SIRT5 belongs to the
Sir2-like proteins precursor; n=1; Aspergillus
niger|Rep: Function: human SIRT5 belongs to the
Sir2-like proteins precursor - Aspergillus niger
Length = 258
Score = 74.9 bits (176), Expect = 9e-13
Identities = 44/108 (40%), Positives = 63/108 (58%), Gaps = 6/108 (5%)
Frame = +2
Query: 2 PVKLLPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMST--CDVCLVVGTSSVVYPA 175
P + LPHC + G LLRP +VWFGESL ++ + ++ D+ LVVGTSS VYPA
Sbjct: 145 PYEELPHCPECKDG-LLRPGVVWFGESLPSHTIDYVDEWLNKGKVDLILVVGTSSRVYPA 203
Query: 176 AMFAPQAASRGAIVAEFNIE----PTPATPDFHFYFEGPCGTTLPQAL 307
A + +A S+GA VA N++ + ++FEG GT +P+ L
Sbjct: 204 AGYVDKARSKGARVAVVNMDRNDVGSSGLKPGDWFFEGDAGTIVPEIL 251
>UniRef50_Q4APN6 Cluster: Silent information regulator protein Sir2;
n=1; Chlorobium phaeobacteroides BS1|Rep: Silent
information regulator protein Sir2 - Chlorobium
phaeobacteroides BS1
Length = 217
Score = 70.9 bits (166), Expect = 2e-11
Identities = 34/95 (35%), Positives = 52/95 (54%)
Frame = +2
Query: 29 KAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQAASRG 208
+ CG LRP I+WFG+ L+ ++ A A+ CD+ + +GTS V+PAA F A G
Sbjct: 123 RCDCGDRLRPDIIWFGDMLDAVVMSKASQAIRNCDLFVSIGTSGTVWPAAGFPDLAKQSG 182
Query: 209 AIVAEFNIEPTPATPDFHFYFEGPCGTTLPQALAD 313
A E N EP+ A+ ++ G G LP+ ++
Sbjct: 183 AYCIEINPEPSGAS-EYDRVIVGNAGEVLPELFSE 216
>UniRef50_A1CTI6 Cluster: SIR2 family histone deacetylase, putative;
n=8; Eurotiomycetidae|Rep: SIR2 family histone
deacetylase, putative - Aspergillus clavatus
Length = 320
Score = 70.1 bits (164), Expect = 3e-11
Identities = 42/105 (40%), Positives = 58/105 (55%), Gaps = 7/105 (6%)
Frame = +2
Query: 14 LPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMST---CDVCLVVGTSSVVYPAAMF 184
LPHC + G LLRP +VWFGESL L A + M + D+ LV+GTSS VYPAA +
Sbjct: 210 LPHCPECKEG-LLRPGVVWFGESLPSQTLRAVDKWMDSGPKVDLILVIGTSSRVYPAAGY 268
Query: 185 APQAASRGAIVAEFNIE----PTPATPDFHFYFEGPCGTTLPQAL 307
+A GA VA N++ + ++F+G G +P+ L
Sbjct: 269 VDRARQLGAKVAVINMDRNDVGSSGLKTGDWFFQGDAGVIIPEIL 313
>UniRef50_Q607X6 Cluster: NAD-dependent deacetylase; n=1;
Methylococcus capsulatus|Rep: NAD-dependent deacetylase
- Methylococcus capsulatus
Length = 255
Score = 69.7 bits (163), Expect = 3e-11
Identities = 36/97 (37%), Positives = 48/97 (49%)
Frame = +2
Query: 17 PHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQA 196
P C A CGA +RP +VW GE+L +AA A CD+ +GTS++V+PAA
Sbjct: 153 PRC--ARCGAPVRPGVVWLGENLPQAAWDAARQAAEDCDLMFSIGTSALVWPAAQLPALV 210
Query: 197 ASRGAIVAEFNIEPTPATPDFHFYFEGPCGTTLPQAL 307
A RGA V + N T + G G +P L
Sbjct: 211 ARRGATVVQVNPAETALDGHAGYNLRGAAGKVMPLLL 247
>UniRef50_Q9I4L0 Cluster: NAD-dependent deacetylase 1; n=10;
Bacteria|Rep: NAD-dependent deacetylase 1 - Pseudomonas
aeruginosa
Length = 250
Score = 69.3 bits (162), Expect = 5e-11
Identities = 39/97 (40%), Positives = 45/97 (46%)
Frame = +2
Query: 17 PHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQA 196
P C CG +RP +VWFGE+L L A A CD+ L VGTS VV PAA A
Sbjct: 150 PRCPA--CGGQVRPGVVWFGEALPEAALREAFAAACECDLLLSVGTSGVVQPAARIPGLA 207
Query: 197 ASRGAIVAEFNIEPTPATPDFHFYFEGPCGTTLPQAL 307
GA V N +P GP G LP+ L
Sbjct: 208 LEHGASVVHVNPQPVRTRHPREHCLVGPAGEVLPELL 244
>UniRef50_Q0LN22 Cluster: Silent information regulator protein Sir2;
n=1; Herpetosiphon aurantiacus ATCC 23779|Rep: Silent
information regulator protein Sir2 - Herpetosiphon
aurantiacus ATCC 23779
Length = 243
Score = 68.9 bits (161), Expect = 6e-11
Identities = 39/92 (42%), Positives = 50/92 (54%)
Frame = +2
Query: 38 CGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQAASRGAIV 217
CGA LRP IVWFGE L+ IL+AA+ A + DV LV+GTS++V P A +A R V
Sbjct: 149 CGAPLRPDIVWFGELLDAGILQAAKAAFDSSDVALVIGTSAIVEPIASLPHRALRRKKTV 208
Query: 218 AEFNIEPTPATPDFHFYFEGPCGTTLPQALAD 313
E N + P F G LPQ + +
Sbjct: 209 IEINPD-IPLRGIATFSLAGSADELLPQLIKE 239
>UniRef50_A7DQD6 Cluster: Silent information regulator protein Sir2;
n=1; Candidatus Nitrosopumilus maritimus SCM1|Rep:
Silent information regulator protein Sir2 - Candidatus
Nitrosopumilus maritimus SCM1
Length = 242
Score = 68.5 bits (160), Expect = 8e-11
Identities = 35/95 (36%), Positives = 49/95 (51%)
Frame = +2
Query: 17 PHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQA 196
P CK CG++LRP +VWFGESL D+ + A + CD+ ++VGTS VV PA A
Sbjct: 143 PLCK---CGSILRPDVVWFGESLPQDVWQEAIIHANQCDLMIIVGTSLVVSPANTLPIYA 199
Query: 197 ASRGAIVAEFNIEPTPATPDFHFYFEGPCGTTLPQ 301
A++ E N E T + + LP+
Sbjct: 200 KQNNAMLIEINPENTEMSSEMDLVIRNTSANALPE 234
>UniRef50_Q21KQ1 Cluster: Silent information regulator protein Sir2;
n=2; Gammaproteobacteria|Rep: Silent information
regulator protein Sir2 - Saccharophagus degradans
(strain 2-40 / ATCC 43961 / DSM 17024)
Length = 235
Score = 68.1 bits (159), Expect = 1e-10
Identities = 35/84 (41%), Positives = 47/84 (55%)
Frame = +2
Query: 47 LLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQAASRGAIVAEF 226
LLRPHIVWFGE ++ E A+ CD+ + +GTS VYPAA F AAS GA E
Sbjct: 148 LLRPHIVWFGEMPL--AMDTIEQALCECDLFVSIGTSGNVYPAAGFVELAASYGATTVEL 205
Query: 227 NIEPTPATPDFHFYFEGPCGTTLP 298
N++ + + F +GP +P
Sbjct: 206 NLDASANSRAFDTSLQGPASELVP 229
>UniRef50_A1FG80 Cluster: Silent information regulator protein Sir2;
n=3; Pseudomonas|Rep: Silent information regulator
protein Sir2 - Pseudomonas putida W619
Length = 252
Score = 68.1 bits (159), Expect = 1e-10
Identities = 38/98 (38%), Positives = 47/98 (47%)
Frame = +2
Query: 17 PHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQA 196
P C++ C LRP IVWFGE L + +AA A CD+ L +GTS VV PAA A
Sbjct: 153 PRCRR--CNGRLRPAIVWFGEYLPPGVWKAASQAARQCDILLSIGTSGVVRPAADLPDIA 210
Query: 197 ASRGAIVAEFNIEPTPATPDFHFYFEGPCGTTLPQALA 310
+ GA+V N GP LPQ +A
Sbjct: 211 LASGAVVIHVNNVDVSMNGPNEIMLIGPAEKILPQLIA 248
>UniRef50_Q88BY5 Cluster: NAD-dependent deacetylase; n=9;
Bacteria|Rep: NAD-dependent deacetylase - Pseudomonas
putida (strain KT2440)
Length = 262
Score = 66.1 bits (154), Expect = 4e-10
Identities = 36/97 (37%), Positives = 46/97 (47%)
Frame = +2
Query: 17 PHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQA 196
P C + C LRP +VWF E+L + +A + CD+ + VGTS VV PAA A
Sbjct: 153 PRCTR--CNGRLRPGVVWFRENLPDNAWRSAVRLVRACDLLVSVGTSGVVMPAAGIPDMA 210
Query: 197 ASRGAIVAEFNIEPTPATPDFHFYFEGPCGTTLPQAL 307
+ GA V N+E EGP G LP L
Sbjct: 211 LAVGATVIHVNLEDVGMDGADEIMLEGPAGVVLPALL 247
>UniRef50_A4RCT8 Cluster: Putative uncharacterized protein; n=3;
Magnaporthe grisea|Rep: Putative uncharacterized protein
- Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 1040
Score = 65.3 bits (152), Expect = 8e-10
Identities = 36/79 (45%), Positives = 47/79 (59%), Gaps = 4/79 (5%)
Frame = +2
Query: 8 KLLPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMST----CDVCLVVGTSSVVYPA 175
K LP C K LLRP IVWFGESL D ++ A+ D+CLV+GTS+ V+PA
Sbjct: 244 KDLPQCPKCK-SELLRPGIVWFGESLPEDTVDKADALFQDEADPIDLCLVIGTSAKVWPA 302
Query: 176 AMFAPQAASRGAIVAEFNI 232
A + +A +GA VA N+
Sbjct: 303 AGYVDEARDKGARVAVVNL 321
>UniRef50_A6SP88 Cluster: Putative uncharacterized protein; n=2;
Sclerotiniaceae|Rep: Putative uncharacterized protein -
Botryotinia fuckeliana B05.10
Length = 332
Score = 64.1 bits (149), Expect = 2e-09
Identities = 35/76 (46%), Positives = 47/76 (61%), Gaps = 2/76 (2%)
Frame = +2
Query: 14 LPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAM--STCDVCLVVGTSSVVYPAAMFA 187
LPHC + ALLRP IVWFGE+L D L+ + + + D+ LVVGT++ VYPAA +
Sbjct: 213 LPHCPQCTT-ALLRPDIVWFGEALPEDTLDEVDRWIDKAPVDLILVVGTTAKVYPAAGYV 271
Query: 188 PQAASRGAIVAEFNIE 235
A GA VA N++
Sbjct: 272 DVARGAGARVAVINMD 287
>UniRef50_A7SK95 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 323
Score = 63.7 bits (148), Expect = 2e-09
Identities = 32/96 (33%), Positives = 52/96 (54%)
Frame = +2
Query: 14 LPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQ 193
+P CK CG +L+P +V+FG+S+ I+ A ++ D ++G++ VY + FA +
Sbjct: 223 VPPCKA--CGGILKPEVVFFGDSVPKQIVNIAYDRLAESDALWIIGSTVEVYSSYRFATE 280
Query: 194 AASRGAIVAEFNIEPTPATPDFHFYFEGPCGTTLPQ 301
A+ +G +A NI T A G CGT LP+
Sbjct: 281 ASKQGKPIAILNIGKTRADKLASLKVSGVCGTVLPK 316
>UniRef50_Q7S223 Cluster: Putative uncharacterized protein
NCU05973.1; n=1; Neurospora crassa|Rep: Putative
uncharacterized protein NCU05973.1 - Neurospora crassa
Length = 334
Score = 63.7 bits (148), Expect = 2e-09
Identities = 37/82 (45%), Positives = 49/82 (59%), Gaps = 4/82 (4%)
Frame = +2
Query: 2 PVKLLPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMST---CDVCLVVGTSSVVYP 172
P LPHC + C LLRP +VWFGESL +L + + D+ LV+GTSSVVYP
Sbjct: 197 PKSHLPHCPQ--CKNLLRPGVVWFGESLNPGMLAEIDAWIDQGGPIDIVLVIGTSSVVYP 254
Query: 173 AAMFAPQAASRG-AIVAEFNIE 235
AA +A +A ++G V N+E
Sbjct: 255 AAGYAEKARTKGKTSVVTVNME 276
>UniRef50_A3LRA1 Cluster: Transcriptional regulatory protein; n=2;
Saccharomycetales|Rep: Transcriptional regulatory
protein - Pichia stipitis (Yeast)
Length = 311
Score = 63.7 bits (148), Expect = 2e-09
Identities = 31/81 (38%), Positives = 48/81 (59%), Gaps = 3/81 (3%)
Frame = +2
Query: 2 PVKLLPHCKKAHCGALLRPHIVWFGESLEHDILEAAEH---AMSTCDVCLVVGTSSVVYP 172
P LP C G+LLRP +VWFGESL +++ + ++ + ++ D+ LV+GTS VYP
Sbjct: 196 PESELPQCPVCKDGSLLRPGVVWFGESLPLNVMNSVDNFIESNNSVDLILVIGTSGTVYP 255
Query: 173 AAMFAPQAASRGAIVAEFNIE 235
A + + +G VA FN +
Sbjct: 256 ANSYVDRVKVKGGKVAIFNTD 276
>UniRef50_Q6C8C7 Cluster: Similar to DEHA0C01507g Debaryomyces
hansenii IPF 2468.1; n=2; Ascomycota|Rep: Similar to
DEHA0C01507g Debaryomyces hansenii IPF 2468.1 - Yarrowia
lipolytica (Candida lipolytica)
Length = 303
Score = 63.3 bits (147), Expect = 3e-09
Identities = 36/81 (44%), Positives = 48/81 (59%), Gaps = 3/81 (3%)
Frame = +2
Query: 2 PVKLLPHCKKAHCG-ALLRPHIVWFGESLEHDILEAAEHAM--STCDVCLVVGTSSVVYP 172
PV+ LP C HC LLRP +VWFGESL ++ A+ + D+ +VVGTS V+P
Sbjct: 169 PVEDLPTCP--HCKEGLLRPGVVWFGESLPFKVMNTADEFLEDEDVDLIIVVGTSGSVWP 226
Query: 173 AAMFAPQAASRGAIVAEFNIE 235
AA + + A G VA FN+E
Sbjct: 227 AAGYVERVALSGGKVAIFNME 247
>UniRef50_Q3S8X8 Cluster: IS-Sir2; n=3; Pseudomonas syringae
group|Rep: IS-Sir2 - Pseudomonas syringae pv.
phaseolicola
Length = 182
Score = 62.9 bits (146), Expect = 4e-09
Identities = 35/94 (37%), Positives = 42/94 (44%)
Frame = +2
Query: 17 PHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQA 196
P C + C LRP +VWFGE L + + A A CDV L +GTS VV+PAA A
Sbjct: 78 PRCPR--CNGKLRPGVVWFGEDLPIAVWKRAVGAAQGCDVLLSIGTSGVVFPAAEIPRIA 135
Query: 197 ASRGAIVAEFNIEPTPATPDFHFYFEGPCGTTLP 298
GA V N TP G +P
Sbjct: 136 LKSGARVVHINTTETPLESPLEMSLIGRAAVCVP 169
>UniRef50_Q2LSF2 Cluster: Sir2 family of NAD+-dependent deacetylase;
n=2; Syntrophus aciditrophicus SB|Rep: Sir2 family of
NAD+-dependent deacetylase - Syntrophus aciditrophicus
(strain SB)
Length = 271
Score = 62.5 bits (145), Expect = 5e-09
Identities = 33/97 (34%), Positives = 48/97 (49%)
Frame = +2
Query: 17 PHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQA 196
P C K C L++P +++FGE+L L A CD+ LV+G+S VVYPAA A
Sbjct: 165 PFCAK--CQGLMKPDVIFFGEALPEKTLRDATWQARNCDLLLVIGSSLVVYPAAYMPMYA 222
Query: 197 ASRGAIVAEFNIEPTPATPDFHFYFEGPCGTTLPQAL 307
GA + N + TP + +G G + + L
Sbjct: 223 KDAGARLVIINRDETPYDSEADVLLQGSAGEIMSRIL 259
>UniRef50_Q6BVM7 Cluster: Similar to CA4170|IPF7784 Candida
albicans; n=2; Saccharomycetaceae|Rep: Similar to
CA4170|IPF7784 Candida albicans - Debaryomyces hansenii
(Yeast) (Torulaspora hansenii)
Length = 301
Score = 62.1 bits (144), Expect = 7e-09
Identities = 31/80 (38%), Positives = 45/80 (56%), Gaps = 2/80 (2%)
Frame = +2
Query: 2 PVKLLPHCKKAHCGALLRPHIVWFGESLEHDILEAAEH--AMSTCDVCLVVGTSSVVYPA 175
P + LP C G+LLRP +VWFGESL ++ ++ + D+ LV+GTS VYPA
Sbjct: 187 PEEELPQCPVCEDGSLLRPGVVWFGESLPLQTIDKIDNFIELDKIDLILVIGTSGTVYPA 246
Query: 176 AMFAPQAASRGAIVAEFNIE 235
+ + +G VA FN +
Sbjct: 247 NSYVDRIKLKGGKVAIFNTD 266
>UniRef50_Q8F3Z6 Cluster: NAD-dependent deacetylase; n=4;
Leptospira|Rep: NAD-dependent deacetylase - Leptospira
interrogans
Length = 246
Score = 60.9 bits (141), Expect = 2e-08
Identities = 33/101 (32%), Positives = 50/101 (49%)
Frame = +2
Query: 11 LLPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAP 190
L P C+ +C + LRP +VWFGES + L + M D+ LV+GTS V A
Sbjct: 142 LPPQCQ--NCNSFLRPGVVWFGESYDDFKLNLSIQRMKHTDLLLVLGTSGSVSMPVYLAQ 199
Query: 191 QAASRGAIVAEFNIEPTPATPDFHFYFEGPCGTTLPQALAD 313
A GA++ E N E + + + +G G LP+ + +
Sbjct: 200 IAKDSGALLIEINPERSSFSSSVDLFLQGKTGEVLPELIRE 240
>UniRef50_Q6MJJ2 Cluster: NAD-dependent deacetylase; n=5;
Proteobacteria|Rep: NAD-dependent deacetylase -
Bdellovibrio bacteriovorus
Length = 235
Score = 60.9 bits (141), Expect = 2e-08
Identities = 36/91 (39%), Positives = 47/91 (51%), Gaps = 2/91 (2%)
Frame = +2
Query: 35 HCGAL--LRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQAASRG 208
HCG +RP IVWFGE H +E A+ D + +GTS VYPAA F A
Sbjct: 142 HCGRKGGVRPDIVWFGEMPHH--MEEIYEALDKADYFISIGTSGNVYPAAGFVRLAWKAK 199
Query: 209 AIVAEFNIEPTPATPDFHFYFEGPCGTTLPQ 301
I E N++ T +P F +F GP T +P+
Sbjct: 200 KI--EINLKDTEISPAFDEHFVGPASTEVPR 228
>UniRef50_A0LG97 Cluster: Silent information regulator protein Sir2;
n=1; Syntrophobacter fumaroxidans MPOB|Rep: Silent
information regulator protein Sir2 - Syntrophobacter
fumaroxidans (strain DSM 10017 / MPOB)
Length = 248
Score = 60.5 bits (140), Expect = 2e-08
Identities = 33/78 (42%), Positives = 42/78 (53%), Gaps = 3/78 (3%)
Frame = +2
Query: 38 CGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQAASRGAIV 217
CG LRP IV+FGE + +A +A CD ++VGTS+ V PA+ A SRGA +
Sbjct: 149 CGNALRPEIVFFGEDIPPQAYRSALNAAQKCDFMMIVGTSASVAPASQLPLVAKSRGAFI 208
Query: 218 AEFN---IEPTPATPDFH 262
E N E T T D H
Sbjct: 209 LEINPMDSELTRRTTDLH 226
>UniRef50_Q8FRV5 Cluster: NAD-dependent deacetylase 2; n=9;
Corynebacterineae|Rep: NAD-dependent deacetylase 2 -
Corynebacterium efficiens
Length = 254
Score = 60.5 bits (140), Expect = 2e-08
Identities = 31/80 (38%), Positives = 43/80 (53%)
Frame = +2
Query: 2 PVKLLPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAM 181
PV+ L + CG +RP +VWFGE+L + AE M D+ ++VGTS +VYPAA
Sbjct: 148 PVERLAPPTCSLCGNPVRPGVVWFGEALPQEEWAVAERRMREADLVVIVGTSGIVYPAAS 207
Query: 182 FAPQAASRGAIVAEFNIEPT 241
A RG + E + T
Sbjct: 208 LPVLAHQRGVPILEITPKET 227
>UniRef50_A5USR3 Cluster: Silent information regulator protein Sir2;
n=3; Chloroflexi (class)|Rep: Silent information
regulator protein Sir2 - Roseiflexus sp. RS-1
Length = 259
Score = 59.7 bits (138), Expect = 4e-08
Identities = 31/67 (46%), Positives = 35/67 (52%)
Frame = +2
Query: 17 PHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQA 196
P C CG+LLRP +V FGE L H L A A+ CDV L VGT + P A F A
Sbjct: 147 PRC--VQCGSLLRPDVVMFGEGLPHHELRRARQAVEQCDVFLCVGTVGAIEPVASFPFVA 204
Query: 197 ASRGAIV 217
GA V
Sbjct: 205 RRHGAFV 211
>UniRef50_Q67KQ0 Cluster: NAD-dependent deacetylase; n=1;
Symbiobacterium thermophilum|Rep: NAD-dependent
deacetylase - Symbiobacterium thermophilum
Length = 251
Score = 59.3 bits (137), Expect = 5e-08
Identities = 36/100 (36%), Positives = 49/100 (49%)
Frame = +2
Query: 14 LPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQ 193
+P C + CG +L+P +V F E+L D +EAA A D+ LVVG+S V PA
Sbjct: 149 IPRCPE--CGGVLKPGVVLFEEALPADAIEAAIEAAMKADLFLVVGSSLEVGPANQLPVL 206
Query: 194 AASRGAIVAEFNIEPTPATPDFHFYFEGPCGTTLPQALAD 313
A G +A FN+ PT P + F G L A+
Sbjct: 207 AVQHGGRLAIFNLTPTFLDPRATWIFREKAGQALGALAAE 246
>UniRef50_A5DW75 Cluster: Putative uncharacterized protein; n=1;
Lodderomyces elongisporus NRRL YB-4239|Rep: Putative
uncharacterized protein - Lodderomyces elongisporus
(Yeast) (Saccharomyces elongisporus)
Length = 379
Score = 58.8 bits (136), Expect = 7e-08
Identities = 32/79 (40%), Positives = 44/79 (55%), Gaps = 3/79 (3%)
Frame = +2
Query: 8 KLLPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAM---STCDVCLVVGTSSVVYPAA 178
K LP C C LLRP +VWFGESL D++ ++ + D+ LV+GTS VYPA
Sbjct: 268 KDLPRCPV--CSELLRPGVVWFGESLPLDVITKIDNFIEEDGPVDLILVIGTSGTVYPAN 325
Query: 179 MFAPQAASRGAIVAEFNIE 235
+ + +G VA FN +
Sbjct: 326 SYVERVKYQGGKVAIFNTD 344
>UniRef50_Q89EA6 Cluster: NAD-dependent deacetylase 2; n=9;
Proteobacteria|Rep: NAD-dependent deacetylase 2 -
Bradyrhizobium japonicum
Length = 273
Score = 58.4 bits (135), Expect = 9e-08
Identities = 31/94 (32%), Positives = 48/94 (51%)
Frame = +2
Query: 14 LPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQ 193
+P C+ CG +L+P +V+FGE++ D++ A+ +S D L+VG+S +VY F
Sbjct: 178 VPACEA--CGGILKPDVVFFGENVPRDVVATAQDHLSQADAMLIVGSSLMVYSGFRFVQA 235
Query: 194 AASRGAIVAEFNIEPTPATPDFHFYFEGPCGTTL 295
AA R +A N+ T A E C L
Sbjct: 236 AAQRQIPIAAVNLGRTRADDLLTLKVEERCEAAL 269
>UniRef50_A7B9E8 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 251
Score = 58.0 bits (134), Expect = 1e-07
Identities = 35/98 (35%), Positives = 48/98 (48%)
Frame = +2
Query: 14 LPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQ 193
+P C C + +RP IV +GESL+ ++EAA A+S +V GTS VVYPAA
Sbjct: 147 VPACPS--CASQMRPDIVMYGESLDQGVIEAAVSAISRASTLIVAGTSLVVYPAAGLINY 204
Query: 194 AASRGAIVAEFNIEPTPATPDFHFYFEGPCGTTLPQAL 307
+ G + N PT A P G TL + +
Sbjct: 205 FS--GDHLVLLNATPTSADAHADLIIREPVGATLDRVM 240
>UniRef50_A2DZ01 Cluster: Transcriptional regulator, Sir2 family
protein; n=1; Trichomonas vaginalis G3|Rep:
Transcriptional regulator, Sir2 family protein -
Trichomonas vaginalis G3
Length = 281
Score = 57.2 bits (132), Expect = 2e-07
Identities = 25/64 (39%), Positives = 39/64 (60%)
Frame = +2
Query: 38 CGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQAASRGAIV 217
CG++L+P + +F +++ I +AA +A+S+CD+ LVVGT V P F A G I+
Sbjct: 182 CGSVLKPQVAFFEDTIPRHIRDAAYNALSSCDLLLVVGTYCAVDPVLSFVRNAKRNGTIL 241
Query: 218 AEFN 229
E N
Sbjct: 242 VEIN 245
>UniRef50_Q73KE1 Cluster: NAD-dependent deacetylase; n=1; Treponema
denticola|Rep: NAD-dependent deacetylase - Treponema
denticola
Length = 251
Score = 57.2 bits (132), Expect = 2e-07
Identities = 31/76 (40%), Positives = 41/76 (53%)
Frame = +2
Query: 14 LPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQ 193
+P C K CG+ ++P I +FGE+L L AE S D LV+GTS +VYPAA
Sbjct: 151 VPRCPK--CGSPIKPAITFFGEALPQKALMKAETEASKSDFMLVLGTSLLVYPAAALPAY 208
Query: 194 AASRGAIVAEFNIEPT 241
G +A N +PT
Sbjct: 209 TLRNGGKIAIVNNQPT 224
>UniRef50_Q1D737 Cluster: NAD-dependent deacetylase; n=1; Myxococcus
xanthus DK 1622|Rep: NAD-dependent deacetylase -
Myxococcus xanthus (strain DK 1622)
Length = 245
Score = 56.8 bits (131), Expect = 3e-07
Identities = 37/105 (35%), Positives = 45/105 (42%), Gaps = 6/105 (5%)
Frame = +2
Query: 2 PVKLLPHCKKAHCGALLRPHIVWFGESLE-HDILEAAEHAMSTCD-----VCLVVGTSSV 163
P +P C CG LLRPHIVWFGE L+ DI + ++ V L GTS
Sbjct: 137 PAGAVPECDA--CGKLLRPHIVWFGEYLDPADIQRIEDFSLRAATSGGRFVFLAAGTSGA 194
Query: 164 VYPAAMFAPQAASRGAIVAEFNIEPTPATPDFHFYFEGPCGTTLP 298
VYPAA Q G N++P + F G LP
Sbjct: 195 VYPAAGIVDQVRKAGGKTWLVNLDPAENSNRFEHRIVDKSGEVLP 239
>UniRef50_A4J646 Cluster: Silent information regulator protein Sir2;
n=2; Peptococcaceae|Rep: Silent information regulator
protein Sir2 - Desulfotomaculum reducens MI-1
Length = 256
Score = 56.8 bits (131), Expect = 3e-07
Identities = 34/86 (39%), Positives = 44/86 (51%)
Frame = +2
Query: 38 CGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQAASRGAIV 217
CG LLRP +V FG+++ D AE MS C + LV+G+S VYP A PQ +S+ I+
Sbjct: 151 CGGLLRPDVVLFGDAMPEDFF-MAEKVMSGCQLLLVIGSSLQVYPVASL-PQLSSKTVII 208
Query: 218 AEFNIEPTPATPDFHFYFEGPCGTTL 295
N EPT F P L
Sbjct: 209 ---NKEPTTWDKHSDVVFHEPASQVL 231
>UniRef50_Q7WLE5 Cluster: NAD-dependent deacetylase; n=47;
Bacteria|Rep: NAD-dependent deacetylase - Bordetella
bronchiseptica (Alcaligenes bronchisepticus)
Length = 274
Score = 56.8 bits (131), Expect = 3e-07
Identities = 29/100 (29%), Positives = 51/100 (51%)
Frame = +2
Query: 11 LLPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAP 190
++P C + CG +++P +V+FGE++ + ++ A A+ D LVVG+S ++Y F
Sbjct: 177 VVPSCPR--CGGIVKPDVVFFGETVPRERVQRAYAALEHADAVLVVGSSLMLYSGYRFVQ 234
Query: 191 QAASRGAIVAEFNIEPTPATPDFHFYFEGPCGTTLPQALA 310
AA G +A N+ T A PC L + ++
Sbjct: 235 AAARAGLPIAAINLGRTRADDMLALKVSRPCDEVLAEVVS 274
>UniRef50_Q5YR82 Cluster: Putative Sir2 family regulator; n=1;
Nocardia farcinica|Rep: Putative Sir2 family regulator -
Nocardia farcinica
Length = 248
Score = 56.0 bits (129), Expect = 5e-07
Identities = 33/99 (33%), Positives = 45/99 (45%)
Frame = +2
Query: 17 PHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQA 196
P C + CG +L+ + FG+ L+ + A T D+ L VGTS V PAA A
Sbjct: 148 PACPE--CGGILKAATIMFGQQLDQRTMTKAALTAQTSDIFLAVGTSLQVEPAASMCALA 205
Query: 197 ASRGAIVAEFNIEPTPATPDFHFYFEGPCGTTLPQALAD 313
GA + N EPTP P GT LP+ + +
Sbjct: 206 VDAGADLVIVNAEPTPYDSIATEVVHEPIGTALPRLVKE 244
>UniRef50_Q8ZFR1 Cluster: NAD-dependent deacetylase; n=149; cellular
organisms|Rep: NAD-dependent deacetylase - Yersinia
pestis
Length = 278
Score = 56.0 bits (129), Expect = 5e-07
Identities = 32/99 (32%), Positives = 48/99 (48%), Gaps = 3/99 (3%)
Frame = +2
Query: 26 KKAHCGAL---LRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQA 196
++ HC LRPHIVWFGE ++ A++ D + +GTS VYPAA F ++
Sbjct: 170 ERCHCCQFPSPLRPHIVWFGEMPMG--MDDIYQALAEADFFISIGTSGHVYPAAGFVHES 227
Query: 197 ASRGAIVAEFNIEPTPATPDFHFYFEGPCGTTLPQALAD 313
GA E N+EP+ F G +P+ + +
Sbjct: 228 HLHGAHTVELNLEPSQVESQFDEKHYGLASKVVPEYIRE 266
>UniRef50_Q8CJM9 Cluster: NAD-dependent deacetylase 2; n=3;
Actinomycetales|Rep: NAD-dependent deacetylase 2 -
Streptomyces coelicolor
Length = 241
Score = 56.0 bits (129), Expect = 5e-07
Identities = 34/90 (37%), Positives = 41/90 (45%)
Frame = +2
Query: 38 CGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQAASRGAIV 217
CG +L+ V FGE L+ +L A C V + VGTS V PAA A A GA +
Sbjct: 148 CGGVLKTATVMFGERLDPVVLGEAAAISKACQVFVAVGTSLQVEPAAGLARVAVEHGARL 207
Query: 218 AEFNIEPTPATPDFHFYFEGPCGTTLPQAL 307
N EPTP P G+ LP L
Sbjct: 208 VVVNAEPTPYDELADEVIREPIGSALPALL 237
>UniRef50_A5K7T7 Cluster: NAD-dependent deacetylase, putative; n=5;
Plasmodium|Rep: NAD-dependent deacetylase, putative -
Plasmodium vivax
Length = 306
Score = 55.2 bits (127), Expect = 8e-07
Identities = 31/88 (35%), Positives = 45/88 (51%), Gaps = 3/88 (3%)
Frame = +2
Query: 8 KLLPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFA 187
+L P C CG + +P++V FGE + +L+ AE + CD+ LV+GTSS V A
Sbjct: 163 QLPPECP---CGGIFKPNVVLFGEVIPKSLLKQAEKEIDKCDLLLVIGTSSTVSTATNLC 219
Query: 188 PQAASRGAIVAEFNIEPTPAT---PDFH 262
A + + E NI T T D+H
Sbjct: 220 YHAHRKKKKIVEVNISKTYITNRVSDYH 247
>UniRef50_Q75DM1 Cluster: ABL004Wp; n=1; Eremothecium gossypii|Rep:
ABL004Wp - Ashbya gossypii (Yeast) (Eremothecium
gossypii)
Length = 319
Score = 55.2 bits (127), Expect = 8e-07
Identities = 40/105 (38%), Positives = 55/105 (52%), Gaps = 7/105 (6%)
Frame = +2
Query: 14 LPHCKKAHCGALLRPHIVWFGESL---EHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMF 184
LP C + G LLRP +VW GESL + D ++A A D+ LV+GTS ++PA +
Sbjct: 202 LPRCPRCRVG-LLRPGVVWCGESLSLVQMDRVDAFLSAKQKVDLVLVIGTSGRLWPAMGY 260
Query: 185 APQAASRGAIVAEFN--IEPTP--ATPDFHFYFEGPCGTTLPQAL 307
+A G+ +A FN IE A + F+G LPQAL
Sbjct: 261 VERAQLCGSRIAFFNTDIEDAAGVAKNKRMWAFQGNAAELLPQAL 305
>UniRef50_UPI00015B4FA0 Cluster: PREDICTED: similar to chromatin
regulatory protein sir2; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to chromatin regulatory protein sir2
- Nasonia vitripennis
Length = 736
Score = 54.8 bits (126), Expect = 1e-06
Identities = 29/100 (29%), Positives = 45/100 (45%)
Frame = +2
Query: 14 LPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQ 193
+P C K CG +++P IV+FG+++ ++E ++ + D LV+GTS + Q
Sbjct: 637 IPPCSK--CGGIMKPDIVFFGDNVPKQVVERVQNEVEEADSLLVLGTSLTTFSGYRIVLQ 694
Query: 194 AASRGAIVAEFNIEPTPATPDFHFYFEGPCGTTLPQALAD 313
A +A NI T G CG LP D
Sbjct: 695 AVEAVKPIAILNIGDTRGDEHAQIRVHGRCGEILPMLTDD 734
>UniRef50_Q8ZU41 Cluster: NAD-dependent deacetylase 1; n=3;
Pyrobaculum|Rep: NAD-dependent deacetylase 1 -
Pyrobaculum aerophilum
Length = 254
Score = 54.8 bits (126), Expect = 1e-06
Identities = 32/97 (32%), Positives = 44/97 (45%)
Frame = +2
Query: 17 PHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQA 196
P C K CG +++P +V+FGE L D L A +V + +GTS VYPA A
Sbjct: 152 PRCPK--CGGVIKPDVVFFGEPLPQDALREAFMLAEMAEVFMAIGTSLAVYPANQLPLVA 209
Query: 197 ASRGAIVAEFNIEPTPATPDFHFYFEGPCGTTLPQAL 307
RGA + N + T + G LP+ L
Sbjct: 210 KKRGAKLVIINADETYYDFFADYIIRGRAEEVLPKLL 246
>UniRef50_A6PTK3 Cluster: Silent information regulator protein Sir2;
n=1; Victivallis vadensis ATCC BAA-548|Rep: Silent
information regulator protein Sir2 - Victivallis
vadensis ATCC BAA-548
Length = 248
Score = 54.4 bits (125), Expect = 1e-06
Identities = 28/81 (34%), Positives = 43/81 (53%)
Frame = +2
Query: 2 PVKLLPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAM 181
P+ L + CG L++P IV++GE+L+ +L A M ++ LV+G+S V PAA
Sbjct: 142 PLVLAGKVPRCGCGGLVKPDIVFYGENLDEALLNQAFADMEKAELVLVLGSSLTVQPAAS 201
Query: 182 FAPQAASRGAIVAEFNIEPTP 244
A G + N +PTP
Sbjct: 202 LPMAANYGGGKIVIVNAQPTP 222
>UniRef50_Q0LIC7 Cluster: Silent information regulator protein Sir2;
n=2; Bacteria|Rep: Silent information regulator protein
Sir2 - Herpetosiphon aurantiacus ATCC 23779
Length = 244
Score = 54.0 bits (124), Expect = 2e-06
Identities = 33/78 (42%), Positives = 40/78 (51%)
Frame = +2
Query: 14 LPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQ 193
LP C CG LRP IV F E++ A+ ++ CD L VGTS V+PAA FA
Sbjct: 145 LPLCPT--CGKPLRPDIVLFEEAIPVWAETQAKRSLRECDFFLAVGTSGTVFPAAAFART 202
Query: 194 AASRGAIVAEFNIEPTPA 247
A GA N+EP A
Sbjct: 203 AQMLGARTMLVNLEPHAA 220
>UniRef50_A6P1S7 Cluster: Putative uncharacterized protein; n=2;
Bacteria|Rep: Putative uncharacterized protein -
Bacteroides capillosus ATCC 29799
Length = 262
Score = 54.0 bits (124), Expect = 2e-06
Identities = 32/94 (34%), Positives = 45/94 (47%)
Frame = +2
Query: 14 LPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQ 193
+P C K CG ++P +V + E+L+ IL AA A+ D+ ++ GTS VYPAA
Sbjct: 167 VPRCDK--CGGRVKPDVVLYEEALDQQILTAALEAIQKADMLIIGGTSLAVYPAASLVNY 224
Query: 194 AASRGAIVAEFNIEPTPATPDFHFYFEGPCGTTL 295
RG + N PTP + P G L
Sbjct: 225 --YRGNKLVLINKSPTPYDRNADLVIAAPIGQVL 256
>UniRef50_A0NQ49 Cluster: Silent information regulator protein Sir2;
n=1; Stappia aggregata IAM 12614|Rep: Silent information
regulator protein Sir2 - Stappia aggregata IAM 12614
Length = 260
Score = 53.6 bits (123), Expect = 2e-06
Identities = 28/76 (36%), Positives = 41/76 (53%)
Frame = +2
Query: 17 PHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQA 196
P C + C LL+ ++ FG+ + L+ A A S CD+ LV+G+S VV+PAA A
Sbjct: 165 PRCSQ--CDGLLKAAVISFGQQMPERELQRAAEAASACDLFLVLGSSLVVHPAAQLPAVA 222
Query: 197 ASRGAIVAEFNIEPTP 244
GA + N + TP
Sbjct: 223 VQSGAELVILNGQETP 238
>UniRef50_UPI0000499DEA Cluster: Sir2 family transcriptional
regulator; n=1; Entamoeba histolytica HM-1:IMSS|Rep:
Sir2 family transcriptional regulator - Entamoeba
histolytica HM-1:IMSS
Length = 383
Score = 53.2 bits (122), Expect = 3e-06
Identities = 23/53 (43%), Positives = 34/53 (64%)
Frame = +2
Query: 20 HCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAA 178
HC +CG L++P IV+F ESL + E+ + CD+ L++GT+ VVYP A
Sbjct: 279 HC---NCGGLIKPDIVFFNESLPDEFFESIKDKFDDCDMLLIIGTALVVYPFA 328
>UniRef50_A6FYM4 Cluster: Sir2 family protein; n=1; Plesiocystis
pacifica SIR-1|Rep: Sir2 family protein - Plesiocystis
pacifica SIR-1
Length = 297
Score = 53.2 bits (122), Expect = 3e-06
Identities = 28/88 (31%), Positives = 43/88 (48%)
Frame = +2
Query: 38 CGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQAASRGAIV 217
CG LL+P++V+FGE + ++ A + +V V G+S V+ F +A +RG V
Sbjct: 198 CGGLLKPNVVFFGEQVPQATVDQAYAMVEDAEVLAVFGSSLAVFSGLRFVKRAKARGIPV 257
Query: 218 AEFNIEPTPATPDFHFYFEGPCGTTLPQ 301
A N PT P + G LP+
Sbjct: 258 AIINAGPTRGDPLASLKIDARLGEFLPR 285
>UniRef50_UPI0000F1D51E Cluster: PREDICTED: hypothetical protein;
n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 504
Score = 52.8 bits (121), Expect = 4e-06
Identities = 21/44 (47%), Positives = 28/44 (63%)
Frame = +2
Query: 14 LPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLV 145
L C++ C LLRPH+VWFGE+L+ IL E + TCD+ V
Sbjct: 166 LERCEQKACDGLLRPHVVWFGETLDSHILTKVEKELETCDLSAV 209
>UniRef50_A1I9S7 Cluster: NAD-dependent deacetylase; n=1; Candidatus
Desulfococcus oleovorans Hxd3|Rep: NAD-dependent
deacetylase - Candidatus Desulfococcus oleovorans Hxd3
Length = 273
Score = 52.8 bits (121), Expect = 4e-06
Identities = 34/96 (35%), Positives = 46/96 (47%)
Frame = +2
Query: 14 LPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQ 193
+P C CG+ +RP +V FGE++ +E A A +CDV L +GTS VV PAA +
Sbjct: 170 MPDCDL--CGSGMRPDVVMFGETVME--VENAFAAARSCDVMLALGTSGVVTPAAQIPAE 225
Query: 194 AASRGAIVAEFNIEPTPATPDFHFYFEGPCGTTLPQ 301
A + GA V N Y G LP+
Sbjct: 226 AKASGAKVIVINPNENGFARVCDIYISMKTGQALPR 261
>UniRef50_UPI000049971A Cluster: Sir2 family transcriptional
regulator; n=1; Entamoeba histolytica HM-1:IMSS|Rep:
Sir2 family transcriptional regulator - Entamoeba
histolytica HM-1:IMSS
Length = 285
Score = 52.4 bits (120), Expect = 6e-06
Identities = 33/100 (33%), Positives = 45/100 (45%)
Frame = +2
Query: 2 PVKLLPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAM 181
P + +P C K CG LL+ +V FGE L+ + A + D LV+GTS V P +
Sbjct: 165 PSQCIPRCPK--CGGLLKLDVVLFGEKLDRVTYDEVVEASTKTDFLLVIGTSLQVAPCNI 222
Query: 182 FAPQAASRGAIVAEFNIEPTPATPDFHFYFEGPCGTTLPQ 301
+A GA VA N TP F G +P+
Sbjct: 223 IPFRAKHCGAQVAFINCSKTPMDEYADFVVRGDLKEIVPK 262
>UniRef50_UPI00006CB0CC Cluster: transcriptional regulator, Sir2
family protein; n=1; Tetrahymena thermophila SB210|Rep:
transcriptional regulator, Sir2 family protein -
Tetrahymena thermophila SB210
Length = 442
Score = 52.0 bits (119), Expect = 7e-06
Identities = 25/73 (34%), Positives = 41/73 (56%)
Frame = +2
Query: 23 CKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQAAS 202
C+K C L +V+FGES+ +I ++A+ + + D+C+VVGTS V AA +
Sbjct: 209 CQKNGCDGQLHDTLVFFGESVLQNIKQSAQEQIESADLCIVVGTSLTVQSAARLVWISQQ 268
Query: 203 RGAIVAEFNIEPT 241
RG + N++ T
Sbjct: 269 RGIPIVIINLQKT 281
>UniRef50_A6DC77 Cluster: Silent information regulator protein Sir2;
n=1; Caminibacter mediatlanticus TB-2|Rep: Silent
information regulator protein Sir2 - Caminibacter
mediatlanticus TB-2
Length = 243
Score = 52.0 bits (119), Expect = 7e-06
Identities = 26/78 (33%), Positives = 40/78 (51%)
Frame = +2
Query: 17 PHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQA 196
P C K C +L+P V+F E + + E + + D+ LV+GT+ + PA+ A
Sbjct: 145 PLCPK--CNGVLKPDFVFFKEPIPKEAFEKSIYYSQNADIMLVIGTTGEIMPASELPLLA 202
Query: 197 ASRGAIVAEFNIEPTPAT 250
GA + E NIEP+ T
Sbjct: 203 KQNGAAIIEINIEPSNYT 220
>UniRef50_Q9WYW0 Cluster: NAD-dependent deacetylase; n=4;
Thermotoga|Rep: NAD-dependent deacetylase - Thermotoga
maritima
Length = 246
Score = 52.0 bits (119), Expect = 7e-06
Identities = 27/69 (39%), Positives = 38/69 (55%)
Frame = +2
Query: 38 CGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQAASRGAIV 217
C +L+RP+IV+FGE+L D L A S + +V+G+S VVYPAA G +
Sbjct: 151 CNSLIRPNIVFFGENLPQDALREAIGLSSRASLMIVLGSSLVVYPAAELPLITVRSGGKL 210
Query: 218 AEFNIEPTP 244
N+ TP
Sbjct: 211 VIVNLGETP 219
>UniRef50_Q2YZT2 Cluster: Putative uncharacterized protein; n=1;
uncultured delta proteobacterium|Rep: Putative
uncharacterized protein - uncultured delta
proteobacterium
Length = 254
Score = 51.6 bits (118), Expect = 1e-05
Identities = 24/68 (35%), Positives = 38/68 (55%)
Frame = +2
Query: 38 CGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQAASRGAIV 217
C ++RP +V+FGE++ A + C + LV+GTS+ V PA+ +A GAI+
Sbjct: 150 CKGVIRPDVVFFGETIPAHATRMAGKEVEKCAMILVIGTSADVAPASRLPIKAKEGGAII 209
Query: 218 AEFNIEPT 241
E N+ T
Sbjct: 210 VEINLRET 217
>UniRef50_UPI000049979A Cluster: Sir2 family transcriptional
regulator; n=1; Entamoeba histolytica HM-1:IMSS|Rep:
Sir2 family transcriptional regulator - Entamoeba
histolytica HM-1:IMSS
Length = 319
Score = 51.2 bits (117), Expect = 1e-05
Identities = 29/72 (40%), Positives = 38/72 (52%)
Frame = +2
Query: 14 LPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQ 193
+P C K CG L++ +V FGE LE + E A S+ DV LV+G+S V PA +
Sbjct: 162 IPRCPK--CGGLIKLDVVLFGEQLEKEKFEKAFEVASSSDVFLVIGSSLEVMPANALPRK 219
Query: 194 AASRGAIVAEFN 229
A A VA N
Sbjct: 220 AKMNSATVAYIN 231
>UniRef50_Q011Q8 Cluster: NAD-dependent deacetylase SIRT2; n=2;
Ostreococcus|Rep: NAD-dependent deacetylase SIRT2 -
Ostreococcus tauri
Length = 394
Score = 50.8 bits (116), Expect = 2e-05
Identities = 23/52 (44%), Positives = 32/52 (61%)
Frame = +2
Query: 23 CKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAA 178
C K CG ++P IV+FGE+L E A+ CD+ +V+GTS VV+P A
Sbjct: 244 CSK--CGEYVKPDIVFFGENLPRRFFECAQEDFEVCDLLIVIGTSLVVHPFA 293
>UniRef50_Q12Y78 Cluster: Silent information regulator protein Sir2;
n=1; Methanococcoides burtonii DSM 6242|Rep: Silent
information regulator protein Sir2 - Methanococcoides
burtonii (strain DSM 6242)
Length = 245
Score = 50.8 bits (116), Expect = 2e-05
Identities = 28/76 (36%), Positives = 39/76 (51%)
Frame = +2
Query: 17 PHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQA 196
P C + CG L++P IV++GE L D +E A S D+ LV+G++ VV PAA
Sbjct: 145 PLCNE--CGGLVKPDIVFYGEMLRQDTIEKAIQESSKADLMLVLGSTLVVQPAASLPLYT 202
Query: 197 ASRGAIVAEFNIEPTP 244
G + N TP
Sbjct: 203 IENGGELVIVNDMKTP 218
>UniRef50_Q54QE6 Cluster: Zn finger-containing protein; n=5;
Eukaryota|Rep: Zn finger-containing protein -
Dictyostelium discoideum AX4
Length = 512
Score = 50.0 bits (114), Expect = 3e-05
Identities = 31/90 (34%), Positives = 42/90 (46%), Gaps = 1/90 (1%)
Frame = +2
Query: 14 LPHCKKAH-CGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAP 190
LP C + C +++P IV+FGESL + A + CD+ LV+GTS V+P A
Sbjct: 390 LPECTETSGCKGIVKPDIVFFGESLPSRFNDCAREDFTKCDLLLVIGTSLKVHPFASLIN 449
Query: 191 QAASRGAIVAEFNIEPTPATPDFHFYFEGP 280
A +G N E P F F P
Sbjct: 450 FA--KGCPRVLINFEEVGTNPYGGFKFNQP 477
>UniRef50_A0PU12 Cluster: Sir2-like regulatory protein; n=1;
Mycobacterium ulcerans Agy99|Rep: Sir2-like regulatory
protein - Mycobacterium ulcerans (strain Agy99)
Length = 283
Score = 49.6 bits (113), Expect = 4e-05
Identities = 25/64 (39%), Positives = 36/64 (56%)
Frame = +2
Query: 38 CGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQAASRGAIV 217
CG +L+P IV+FGES+ + ++ A + D LV G+S V+ F AA+RG V
Sbjct: 179 CGGMLKPDIVYFGESVPKEPVDQAFSLVDQSDALLVAGSSLTVFSGYRFLRHAAARGIPV 238
Query: 218 AEFN 229
A N
Sbjct: 239 AIIN 242
>UniRef50_Q54LF0 Cluster: Ankyrin repeat-containing protein; n=1;
Dictyostelium discoideum AX4|Rep: Ankyrin
repeat-containing protein - Dictyostelium discoideum AX4
Length = 778
Score = 49.6 bits (113), Expect = 4e-05
Identities = 27/76 (35%), Positives = 38/76 (50%)
Frame = +2
Query: 14 LPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQ 193
LP C + C ++RP++V+FGE L D D+ +V+GTS +VYP A
Sbjct: 639 LPFCTEPECRHVIRPNVVFFGEPLSQDFRVNTITDFRKADLLIVMGTSLIVYPFASLVND 698
Query: 194 AASRGAIVAEFNIEPT 241
AS + FN E T
Sbjct: 699 VASDVPRLL-FNFEST 713
>UniRef50_Q8R216 Cluster: NAD-dependent deacetylase sirtuin-4; n=7;
cellular organisms|Rep: NAD-dependent deacetylase
sirtuin-4 - Mus musculus (Mouse)
Length = 333
Score = 49.6 bits (113), Expect = 4e-05
Identities = 29/95 (30%), Positives = 45/95 (47%)
Frame = +2
Query: 14 LPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQ 193
+P C + CG L+P +V+FG+++ D ++ + D LVVG+S VY F
Sbjct: 214 VPCCDR--CGGPLKPDVVFFGDTVNPDKVDFVHRRVKEADSLLVVGSSLQVYSGYRFILT 271
Query: 194 AASRGAIVAEFNIEPTPATPDFHFYFEGPCGTTLP 298
A + +A NI PT + + CG LP
Sbjct: 272 AREQKLPIAILNIGPTRSDDLACLKLDSRCGELLP 306
>UniRef50_Q97MB4 Cluster: NAD-dependent deacetylase; n=7;
Bacteria|Rep: NAD-dependent deacetylase - Clostridium
acetobutylicum
Length = 245
Score = 49.6 bits (113), Expect = 4e-05
Identities = 23/55 (41%), Positives = 35/55 (63%)
Frame = +2
Query: 14 LPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAA 178
+P C K CG +++P +V + E L+ I++ + A+S D +V GTS VVYPAA
Sbjct: 152 IPKCDK--CGGIVKPDVVLYEEGLDDSIIQNSVKAISEADTLIVGGTSLVVYPAA 204
>UniRef50_A7HL19 Cluster: Silent information regulator protein Sir2;
n=1; Fervidobacterium nodosum Rt17-B1|Rep: Silent
information regulator protein Sir2 - Fervidobacterium
nodosum Rt17-B1
Length = 244
Score = 49.2 bits (112), Expect = 5e-05
Identities = 27/71 (38%), Positives = 36/71 (50%)
Frame = +2
Query: 29 KAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQAASRG 208
+ CG + +P IV+FGE L + AE+ DV + +GTS VVYPAA A G
Sbjct: 149 RCECGGVTKPDIVFFGEMLPLNEYSKAENWAKESDVFIAMGTSLVVYPAAQLPIYAKHSG 208
Query: 209 AIVAEFNIEPT 241
A + N T
Sbjct: 209 AKLCIINKNET 219
>UniRef50_A6LP94 Cluster: Silent information regulator protein Sir2;
n=1; Thermosipho melanesiensis BI429|Rep: Silent
information regulator protein Sir2 - Thermosipho
melanesiensis BI429
Length = 234
Score = 49.2 bits (112), Expect = 5e-05
Identities = 29/68 (42%), Positives = 38/68 (55%)
Frame = +2
Query: 38 CGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQAASRGAIV 217
CG L+RP IV+FGE + +DI E + + LV+GTS VYPA+ F RG I+
Sbjct: 139 CGGLIRPDIVFFGEPV-NDIDRVFE-LLDKAETLLVMGTSLQVYPASNFPVYVKERGGIL 196
Query: 218 AEFNIEPT 241
N E T
Sbjct: 197 IIVNREET 204
>UniRef50_A4QUX8 Cluster: Putative uncharacterized protein; n=1;
Magnaporthe grisea|Rep: Putative uncharacterized protein
- Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 460
Score = 49.2 bits (112), Expect = 5e-05
Identities = 25/68 (36%), Positives = 40/68 (58%)
Frame = +2
Query: 8 KLLPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFA 187
+++P C A C L++P+IV+FGE L E H ++ D+ +++GTS VYP A
Sbjct: 177 EIVPRC--ASCNGLVKPNIVFFGEPLPRTFSEKC-HLVAESDLAIIIGTSLTVYPFAGL- 232
Query: 188 PQAASRGA 211
P+ RG+
Sbjct: 233 PELVPRGS 240
>UniRef50_UPI0000519F58 Cluster: PREDICTED: similar to Sirt4
CG3187-PC, isoform C isoform 2; n=2; Endopterygota|Rep:
PREDICTED: similar to Sirt4 CG3187-PC, isoform C isoform
2 - Apis mellifera
Length = 302
Score = 48.8 bits (111), Expect = 7e-05
Identities = 27/94 (28%), Positives = 47/94 (50%)
Frame = +2
Query: 14 LPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQ 193
+P C+K C +L+P I++FG+++ I+E ++ + D L++GT+ + + A Q
Sbjct: 203 VPICEK--CDGILKPDIIFFGDNVPRKIVENIKYNIEHSDSLLIIGTTLTTFSSYRIALQ 260
Query: 194 AASRGAIVAEFNIEPTPATPDFHFYFEGPCGTTL 295
A + G +A NI T EG C L
Sbjct: 261 ANNIGKPIAILNIGKTRVDNLAKIKVEGRCSNVL 294
>UniRef50_A1ZZG3 Cluster: NAD-dependent deacetylase; n=35;
Bacteria|Rep: NAD-dependent deacetylase - Microscilla
marina ATCC 23134
Length = 245
Score = 48.0 bits (109), Expect = 1e-04
Identities = 25/59 (42%), Positives = 37/59 (62%)
Frame = +2
Query: 2 PVKLLPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAA 178
P+ + C+K G+ LRPHIVWFGE++ ++ A + ++ +VVGTS VYPAA
Sbjct: 141 PINIGDKCEK---GSQLRPHIVWFGEAV--PMMTVAIQETHSANLFIVVGTSLAVYPAA 194
>UniRef50_A1HU63 Cluster: Silent information regulator protein Sir2;
n=1; Thermosinus carboxydivorans Nor1|Rep: Silent
information regulator protein Sir2 - Thermosinus
carboxydivorans Nor1
Length = 243
Score = 48.0 bits (109), Expect = 1e-04
Identities = 27/70 (38%), Positives = 41/70 (58%)
Frame = +2
Query: 32 AHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQAASRGA 211
A CGA+LRP +V+FG+ L + AE S D+ LV+G++ V PA + P+ + A
Sbjct: 152 ACCGAVLRPDVVFFGDKLPAETWRHAERLASASDLMLVIGSTLEVAPAC-YLPELSREIA 210
Query: 212 IVAEFNIEPT 241
I+ N+ PT
Sbjct: 211 II---NLGPT 217
>UniRef50_Q9Y6E7 Cluster: NAD-dependent deacetylase sirtuin-4; n=23;
Deuterostomia|Rep: NAD-dependent deacetylase sirtuin-4 -
Homo sapiens (Human)
Length = 314
Score = 48.0 bits (109), Expect = 1e-04
Identities = 29/95 (30%), Positives = 43/95 (45%)
Frame = +2
Query: 14 LPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQ 193
+P C CG L+P +V+FG+++ D ++ + D LVVG+S VY F
Sbjct: 217 VPTC--VQCGGHLKPDVVFFGDTVNPDKVDFVHKRVKEADSLLVVGSSLQVYSGYRFILT 274
Query: 194 AASRGAIVAEFNIEPTPATPDFHFYFEGPCGTTLP 298
A + +A NI PT + CG LP
Sbjct: 275 AWEKKLPIAILNIGPTRSDDLACLKLNSRCGELLP 309
>UniRef50_Q5L014 Cluster: NAD-dependent deacetylase 1; n=7;
Bacillaceae|Rep: NAD-dependent deacetylase 1 -
Geobacillus kaustophilus
Length = 242
Score = 48.0 bits (109), Expect = 1e-04
Identities = 27/68 (39%), Positives = 34/68 (50%)
Frame = +2
Query: 38 CGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQAASRGAIV 217
CG +LRP +V FGE L + A A D+ LV+G+S V PA A GA +
Sbjct: 144 CGGVLRPSVVLFGEPLPEKAITEAWEAAQQADLFLVLGSSLQVSPANQLPLVAKRNGAKL 203
Query: 218 AEFNIEPT 241
N EPT
Sbjct: 204 VIINWEPT 211
>UniRef50_Q974M6 Cluster: NAD-dependent deacetylase; n=8;
Thermoprotei|Rep: NAD-dependent deacetylase - Sulfolobus
tokodaii
Length = 250
Score = 47.6 bits (108), Expect = 2e-04
Identities = 27/72 (37%), Positives = 37/72 (51%)
Frame = +2
Query: 29 KAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQAASRG 208
K CG ++RP +V FGE + ++I A E A D+ L +G+S VYPA M G
Sbjct: 148 KCECGGVIRPDVVLFGEPV-YNISSALEIARE-ADLVLAIGSSLTVYPANMIPLTVKEMG 205
Query: 209 AIVAEFNIEPTP 244
+ N E TP
Sbjct: 206 GKLIILNAEETP 217
>UniRef50_Q8A3H9 Cluster: NAD-dependent deacetylase; n=3;
Bacteroides|Rep: NAD-dependent deacetylase - Bacteroides
thetaiotaomicron
Length = 234
Score = 47.6 bits (108), Expect = 2e-04
Identities = 30/72 (41%), Positives = 40/72 (55%)
Frame = +2
Query: 29 KAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQAASRG 208
KA G LRP IVWFGE++ +E A + D+ +++GTS VYPAA RG
Sbjct: 137 KAGDGTQLRPFIVWFGEAVPE--IETAVRYVEKADIFVIIGTSLNVYPAAGLL-HYVPRG 193
Query: 209 AIVAEFNIEPTP 244
A V + I+P P
Sbjct: 194 AEV--YLIDPKP 203
>UniRef50_Q9USN7 Cluster: Sir2 family histone deacetylase Hst2; n=1;
Schizosaccharomyces pombe|Rep: Sir2 family histone
deacetylase Hst2 - Schizosaccharomyces pombe (Fission
yeast)
Length = 332
Score = 47.2 bits (107), Expect = 2e-04
Identities = 23/57 (40%), Positives = 32/57 (56%)
Frame = +2
Query: 8 KLLPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAA 178
K +P C C L++P IV++GE L E E CD+ LV+GTS +V+P A
Sbjct: 165 KQVPKCNS--CKGLIKPMIVFYGEGLPMRFFEHMEKDTKVCDMALVIGTSLLVHPFA 219
>UniRef50_A1DG07 Cluster: SIR2 family histone deacetylase, putative;
n=3; Trichocomaceae|Rep: SIR2 family histone
deacetylase, putative - Neosartorya fischeri (strain
ATCC 1020 / DSM 3700 / NRRL 181)(Aspergillus
fischerianus (strain ATCC 1020 / DSM 3700 / NRRL 181))
Length = 425
Score = 47.2 bits (107), Expect = 2e-04
Identities = 26/74 (35%), Positives = 37/74 (50%)
Frame = +2
Query: 14 LPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQ 193
+PHC HC ++P IV+FGE+L + A D+C+V+GTS V+P A P
Sbjct: 175 VPHCP--HCNGFVKPDIVFFGEALPEE-FHANRSLPEQADLCIVMGTSLTVHPFASL-PS 230
Query: 194 AASRGAIVAEFNIE 235
G N+E
Sbjct: 231 FCREGVPRVLINME 244
>UniRef50_Q8REC3 Cluster: NAD-dependent deacetylase; n=3;
Fusobacterium nucleatum|Rep: NAD-dependent deacetylase -
Fusobacterium nucleatum subsp. nucleatum
Length = 252
Score = 47.2 bits (107), Expect = 2e-04
Identities = 19/60 (31%), Positives = 32/60 (53%)
Frame = +2
Query: 38 CGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQAASRGAIV 217
CG ++RP + +GE+L ++ A + + D +V GTS VYPAA + + I+
Sbjct: 150 CGGVVRPDVTLYGENLNQSVVNEAIYQLEQADTLIVAGTSLTVYPAAYYLRYFRGKNLII 209
>UniRef50_UPI000023DCB3 Cluster: hypothetical protein FG05505.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG05505.1 - Gibberella zeae PH-1
Length = 330
Score = 46.8 bits (106), Expect = 3e-04
Identities = 23/58 (39%), Positives = 33/58 (56%)
Frame = +2
Query: 47 LLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQAASRGAIVA 220
+L+P +V FGES++ + AAE A+ +VVGTS Y A A +A RG +A
Sbjct: 199 ILKPAVVMFGESIDSHVKNAAEEAIDNAGKLVVVGTSLATYSAWRLAKRAQDRGMPIA 256
>UniRef50_A3JEV2 Cluster: NAD-dependent deacetylase; n=2;
Marinobacter|Rep: NAD-dependent deacetylase -
Marinobacter sp. ELB17
Length = 300
Score = 46.8 bits (106), Expect = 3e-04
Identities = 24/70 (34%), Positives = 37/70 (52%)
Frame = +2
Query: 38 CGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQAASRGAIV 217
CG +L+P +V+FG+ + + AA A+ D LV+G+S +VY F A G +
Sbjct: 208 CGGILKPDVVFFGDYVPKQRVNAALDALKASDGLLVIGSSLMVYSGFRFCRYAHEWGKPI 267
Query: 218 AEFNIEPTPA 247
A N+ T A
Sbjct: 268 ATLNLGRTRA 277
>UniRef50_Q7ZVK3 Cluster: NAD-dependent deacetylase sirtuin-2; n=12;
Coelomata|Rep: NAD-dependent deacetylase sirtuin-2 -
Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 379
Score = 46.8 bits (106), Expect = 3e-04
Identities = 22/64 (34%), Positives = 36/64 (56%)
Frame = +2
Query: 14 LPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQ 193
+P C CG+L++P IV+FGESL + + CD+ +++GTS V P A +
Sbjct: 216 IPKCDS--CGSLVKPDIVFFGESLPSRFFTSMKADFPQCDLLIIMGTSLQVQPFASLVSR 273
Query: 194 AASR 205
++R
Sbjct: 274 VSNR 277
>UniRef50_Q3A6W7 Cluster: NAD-dependent protein deacetylases, SIR2
family; n=2; Pelobacter|Rep: NAD-dependent protein
deacetylases, SIR2 family - Pelobacter carbinolicus
(strain DSM 2380 / Gra Bd 1)
Length = 278
Score = 46.4 bits (105), Expect = 4e-04
Identities = 27/80 (33%), Positives = 42/80 (52%)
Frame = +2
Query: 38 CGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQAASRGAIV 217
C ++L+P IV+FGE + EAAE ++ CD+ LV+G+S V PA++ P +V
Sbjct: 179 CNSVLKPDIVFFGEMVH--AFEAAEQLIAQCDLLLVLGSSLKVTPASLL-PYHTQATTVV 235
Query: 218 AEFNIEPTPATPDFHFYFEG 277
P P F+ +G
Sbjct: 236 VNRGAVMLPPAP-HRFFVDG 254
>UniRef50_Q5V4Q5 Cluster: NAD-dependent deacetylase; n=2;
Halobacteriaceae|Rep: NAD-dependent deacetylase -
Haloarcula marismortui (Halobacterium marismortui)
Length = 260
Score = 46.4 bits (105), Expect = 4e-04
Identities = 24/72 (33%), Positives = 35/72 (48%)
Frame = +2
Query: 29 KAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQAASRG 208
+ CG + RP +V FGE + + A+ DV L VG+S V PA++ AA
Sbjct: 165 RCDCGGVYRPDVVLFGEPMPDVAMNEAQRLARDSDVFLAVGSSLSVQPASLLPKIAAEGD 224
Query: 209 AIVAEFNIEPTP 244
+ + N E TP
Sbjct: 225 STLVVVNYEETP 236
>UniRef50_Q882K4 Cluster: NAD-dependent deacetylase 3; n=5;
Pseudomonas|Rep: NAD-dependent deacetylase 3 -
Pseudomonas syringae pv. tomato
Length = 281
Score = 46.4 bits (105), Expect = 4e-04
Identities = 30/96 (31%), Positives = 42/96 (43%), Gaps = 1/96 (1%)
Frame = +2
Query: 14 LPHCKKAHC-GALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAP 190
+P C HC G L+P +V+FGE++ A ++ + LVVGTS + + A
Sbjct: 179 VPECP--HCQGKRLKPDVVFFGENVASHTAARATLSVEQAEGLLVVGTSLMAWSAFRLCK 236
Query: 191 QAASRGAIVAEFNIEPTPATPDFHFYFEGPCGTTLP 298
A +G V N T A E PC LP
Sbjct: 237 AMAEQGKPVIAINHGKTRADELLRMKIEAPCEQVLP 272
>UniRef50_Q0R0H8 Cluster: Sir2-like protein; n=1; Naegleria sp.
TES-2005|Rep: Sir2-like protein - Naegleria sp. TES-2005
Length = 137
Score = 46.0 bits (104), Expect = 5e-04
Identities = 26/73 (35%), Positives = 35/73 (47%)
Frame = +2
Query: 26 KKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQAASR 205
+K CG LR I+ FGE+L + L A D LV+GTS +V PAA
Sbjct: 25 RKCECGGDLRDTIIHFGENLPINELNIAYKNSQMGDFALVMGTSLMVNPAAALPGMVLEN 84
Query: 206 GAIVAEFNIEPTP 244
G + N++ TP
Sbjct: 85 GGSMCIVNLQKTP 97
>UniRef50_A1A3R7 Cluster: Sir2-type regulatory protein; n=2;
Bifidobacterium adolescentis|Rep: Sir2-type regulatory
protein - Bifidobacterium adolescentis (strain ATCC
15703 / DSM 20083)
Length = 218
Score = 45.6 bits (103), Expect = 7e-04
Identities = 23/76 (30%), Positives = 37/76 (48%)
Frame = +2
Query: 14 LPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQ 193
LP+ C L++ +V+FGE+L +E + + D V+G++ V PAA P
Sbjct: 111 LPYSGNMPCDGLIKTDVVYFGEALPDGAIEKSYRLAAQADELWVIGSTLEVMPAASIVPV 170
Query: 194 AASRGAIVAEFNIEPT 241
AA G + N+ T
Sbjct: 171 AAQAGVPITIMNMGRT 186
>UniRef50_Q1RPU9 Cluster: Zinc finger protein; n=1; Ciona
intestinalis|Rep: Zinc finger protein - Ciona
intestinalis (Transparent sea squirt)
Length = 320
Score = 45.6 bits (103), Expect = 7e-04
Identities = 25/78 (32%), Positives = 40/78 (51%)
Frame = +2
Query: 14 LPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQ 193
+P C+K CG L+P++ +FG+++ + + CD LVVG+S V+ F Q
Sbjct: 225 VPACRK--CGGDLKPNVTFFGDNVPGSKVTFVRSIVDKCDGVLVVGSSLHVWSGYRFITQ 282
Query: 194 AASRGAIVAEFNIEPTPA 247
A G +A N+ T A
Sbjct: 283 AHELGVPIAIVNVGETRA 300
>UniRef50_A4R235 Cluster: Putative uncharacterized protein; n=1;
Magnaporthe grisea|Rep: Putative uncharacterized protein
- Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 315
Score = 45.6 bits (103), Expect = 7e-04
Identities = 35/99 (35%), Positives = 52/99 (52%), Gaps = 4/99 (4%)
Frame = +2
Query: 17 PHCKKAHCGA-LLRPHIVWFGESL-EHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAP 190
PHC A CG L+RP + ++L + D A + A+ DV LVVGT++V+ PA +
Sbjct: 215 PHC--AACGKHLVRPTVQPNRQALADVDDFVARKPAV---DVALVVGTAAVLPPAPRYLH 269
Query: 191 QAASRGAIVAEFNIEPTPA--TPDFHFYFEGPCGTTLPQ 301
+ GA+V N +P A D F+F+G LP+
Sbjct: 270 ETMRHGAVVVVVNPDPAVAEGLRDEDFFFQGDAAEILPR 308
>UniRef50_Q8G465 Cluster: Sir2-type regulatory protein; n=2;
Bifidobacterium longum|Rep: Sir2-type regulatory protein
- Bifidobacterium longum
Length = 216
Score = 45.2 bits (102), Expect = 9e-04
Identities = 21/68 (30%), Positives = 35/68 (51%)
Frame = +2
Query: 38 CGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQAASRGAIV 217
C +++ +V+FGE+L +E + + D V+G++ VYPAA P AA G +
Sbjct: 119 CNGIIKTDVVYFGEALPDGAMEKSYSLATKADELWVIGSTLEVYPAASIVPVAAQAGVPI 178
Query: 218 AEFNIEPT 241
N+ T
Sbjct: 179 TIMNMGHT 186
>UniRef50_Q1QTH0 Cluster: Silent information regulator protein Sir2;
n=2; Oceanospirillales|Rep: Silent information regulator
protein Sir2 - Chromohalobacter salexigens (strain DSM
3043 / ATCC BAA-138 / NCIMB13768)
Length = 242
Score = 45.2 bits (102), Expect = 9e-04
Identities = 25/52 (48%), Positives = 32/52 (61%)
Frame = +2
Query: 41 GALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQA 196
G+ LRP +VWFGE + +A E ++ D+ LVVGTS V PAAM QA
Sbjct: 142 GSQLRPDVVWFGEPVPR-YAQACE-IVAEADLVLVVGTSLAVMPAAMLLDQA 191
>UniRef50_Q4P3S4 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 400
Score = 45.2 bits (102), Expect = 9e-04
Identities = 21/71 (29%), Positives = 36/71 (50%)
Frame = +2
Query: 35 HCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQAASRGAI 214
+CG +L+P +++FGES+ + + + + + L++GTS Y A QA +
Sbjct: 273 NCGGVLKPAVIFFGESVPDKLRDHSYEMVENANAMLLIGTSLATYSAFRLVKQAVEQNKP 332
Query: 215 VAEFNIEPTPA 247
V N PT A
Sbjct: 333 VMVLNRGPTRA 343
>UniRef50_UPI0000E49AD8 Cluster: PREDICTED: similar to NAD-dependent
deacetylase sirtuin 2 homolog; n=1; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to NAD-dependent
deacetylase sirtuin 2 homolog - Strongylocentrotus
purpuratus
Length = 400
Score = 44.8 bits (101), Expect = 0.001
Identities = 21/56 (37%), Positives = 31/56 (55%)
Frame = +2
Query: 11 LLPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAA 178
L+P C K + +++P +V+FGESL CD+ +V+GTS VV P A
Sbjct: 212 LIPRCAKCNETGVVKPDVVFFGESLPPRFPTLVSEDFPQCDLLIVMGTSLVVQPFA 267
>UniRef50_Q54P49 Cluster: Zn finger-containing protein; n=1;
Dictyostelium discoideum AX4|Rep: Zn finger-containing
protein - Dictyostelium discoideum AX4
Length = 456
Score = 44.8 bits (101), Expect = 0.001
Identities = 24/61 (39%), Positives = 36/61 (59%), Gaps = 2/61 (3%)
Frame = +2
Query: 2 PVK-LLPHCKKAHCG-ALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPA 175
P+K ++P CK C A+++P IV+FGESL + ++ CD +V+GTS V P
Sbjct: 323 PLKSVVPRCKVVQCNNAVIKPDIVFFGESLPPIFNQNILDDINRCDCLIVIGTSLKVQPI 382
Query: 176 A 178
A
Sbjct: 383 A 383
>UniRef50_Q25337 Cluster: NAD-dependent deacetylase SIR2 homolog;
n=6; Leishmania|Rep: NAD-dependent deacetylase SIR2
homolog - Leishmania major
Length = 381
Score = 44.8 bits (101), Expect = 0.001
Identities = 16/48 (33%), Positives = 31/48 (64%)
Frame = +2
Query: 38 CGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAM 181
CG +++P++V+FGE+L +A H ++ +++GTS V+P A+
Sbjct: 179 CGGIVKPNVVFFGENLPDAFFDALHHDAPIAELVIIIGTSMQVHPFAL 226
>UniRef50_Q1YSP9 Cluster: NAD-dependent deacetylase; n=1; gamma
proteobacterium HTCC2207|Rep: NAD-dependent deacetylase
- gamma proteobacterium HTCC2207
Length = 270
Score = 44.4 bits (100), Expect = 0.002
Identities = 28/94 (29%), Positives = 43/94 (45%)
Frame = +2
Query: 14 LPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQ 193
+P C+ +CG +L+P V+FG+S+ + AE M D +VVG+S V + F
Sbjct: 171 VPDCE--NCGGVLKPDAVFFGDSVPAQRVADAEQQMKDADGLVVVGSSLVAFSGYRFCLW 228
Query: 194 AASRGAIVAEFNIEPTPATPDFHFYFEGPCGTTL 295
A+ +G + N T G CG L
Sbjct: 229 ASKQGKPIVIINDGKTRGDELATAKVAGLCGDVL 262
>UniRef50_Q4WFZ3 Cluster: SIR2 family histone deacetylase, putative;
n=4; Trichocomaceae|Rep: SIR2 family histone
deacetylase, putative - Aspergillus fumigatus (Sartorya
fumigata)
Length = 403
Score = 44.4 bits (100), Expect = 0.002
Identities = 23/65 (35%), Positives = 37/65 (56%)
Frame = +2
Query: 14 LPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQ 193
+P+C+ CG ++P IV+FG+ L + + E +S D+ LV+GTS V P + P+
Sbjct: 232 VPYCQVPDCGGAVKPDIVFFGQPLPAE-FDEKEKEVSEADMMLVMGTSLKVAPCSRL-PR 289
Query: 194 AASRG 208
A G
Sbjct: 290 LAREG 294
>UniRef50_Q8CNF4 Cluster: NAD-dependent deacetylase; n=17;
Staphylococcus|Rep: NAD-dependent deacetylase -
Staphylococcus epidermidis (strain ATCC 12228)
Length = 246
Score = 44.4 bits (100), Expect = 0.002
Identities = 26/77 (33%), Positives = 40/77 (51%)
Frame = +2
Query: 14 LPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQ 193
L +C+K CG ++RP IV +GE L + A + D +V+G+S VV PAA F +
Sbjct: 149 LKYCEK--CGNVIRPDIVLYGEMLNQKTVFKALDKIQHADTLIVLGSSLVVQPAAGFVSE 206
Query: 194 AASRGAIVAEFNIEPTP 244
++ N + TP
Sbjct: 207 FKGDNLVI--INRDATP 221
>UniRef50_A4M603 Cluster: Silent information regulator protein Sir2;
n=1; Petrotoga mobilis SJ95|Rep: Silent information
regulator protein Sir2 - Petrotoga mobilis SJ95
Length = 256
Score = 44.0 bits (99), Expect = 0.002
Identities = 24/70 (34%), Positives = 44/70 (62%)
Frame = +2
Query: 8 KLLPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFA 187
+++P C +CG +++P IV+FGE +++ L +E M ++ LV+G+S V PAAM
Sbjct: 149 EVVPKCD--NCGGVIKPDIVFFGEPVKY--LTESEILMKNSELVLVLGSSLAVIPAAML- 203
Query: 188 PQAASRGAIV 217
+ ++G I+
Sbjct: 204 -PSLTKGKII 212
>UniRef50_A3WK56 Cluster: SIR2-like regulatory protein,
NAD-dependent protein deacetylase; n=1; Idiomarina
baltica OS145|Rep: SIR2-like regulatory protein,
NAD-dependent protein deacetylase - Idiomarina baltica
OS145
Length = 279
Score = 44.0 bits (99), Expect = 0.002
Identities = 22/61 (36%), Positives = 34/61 (55%)
Frame = +2
Query: 14 LPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQ 193
L HC HCG +L+P +V+FG+++ +EA A+ L+VG+S V+ FA
Sbjct: 177 LIHCD--HCGGILKPDVVYFGDNVPKKRVEACYQAIDDSQGLLIVGSSLKVFSGFRFARY 234
Query: 194 A 196
A
Sbjct: 235 A 235
>UniRef50_Q1D9X2 Cluster: Sir2 family protein; n=1; Myxococcus
xanthus DK 1622|Rep: Sir2 family protein - Myxococcus
xanthus (strain DK 1622)
Length = 287
Score = 43.6 bits (98), Expect = 0.003
Identities = 24/91 (26%), Positives = 42/91 (46%)
Frame = +2
Query: 38 CGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQAASRGAIV 217
CG L+P +V+FG+++ + +A + D LVVG+S ++ F +A+ R +
Sbjct: 192 CGGTLKPDVVFFGDNVPVPTVASAFALLEEGDALLVVGSSLAIFSGYRFLVRASERRMPI 251
Query: 218 AEFNIEPTPATPDFHFYFEGPCGTTLPQALA 310
A N+ + E G LP+ A
Sbjct: 252 AILNLGECRGVELADVHLEARAGDALPRLAA 282
>UniRef50_A1HLU5 Cluster: Silent information regulator protein Sir2;
n=1; Thermosinus carboxydivorans Nor1|Rep: Silent
information regulator protein Sir2 - Thermosinus
carboxydivorans Nor1
Length = 261
Score = 43.6 bits (98), Expect = 0.003
Identities = 26/74 (35%), Positives = 33/74 (44%)
Frame = +2
Query: 23 CKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQAAS 202
C C LRP +V FGESL A D +V+G+S VV PA A
Sbjct: 161 CYCPRCQGQLRPDVVLFGESLPDTAWNEAVRWSRKADFFVVIGSSLVVSPANYLPQLAVE 220
Query: 203 RGAIVAEFNIEPTP 244
+GA + N + TP
Sbjct: 221 QGAKLLIINSDSTP 234
>UniRef50_A2F8E1 Cluster: Transcriptional regulator, Sir2 family
protein; n=1; Trichomonas vaginalis G3|Rep:
Transcriptional regulator, Sir2 family protein -
Trichomonas vaginalis G3
Length = 331
Score = 43.6 bits (98), Expect = 0.003
Identities = 18/56 (32%), Positives = 31/56 (55%)
Frame = +2
Query: 11 LLPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAA 178
++PHC G ++P + +FGE++ + +CD+C++ GTS VYP A
Sbjct: 174 VVPHCPSCD-GEHVKPDVTFFGEAMPDRFEQTLYEDFHSCDLCIITGTSLGVYPFA 228
>UniRef50_A2QFF9 Cluster: Complex: Sir2p is one of four Silent
Information Regulator genes in yeast. Sir2p; n=6;
Pezizomycotina|Rep: Complex: Sir2p is one of four Silent
Information Regulator genes in yeast. Sir2p -
Aspergillus niger
Length = 378
Score = 43.6 bits (98), Expect = 0.003
Identities = 27/74 (36%), Positives = 39/74 (52%)
Frame = +2
Query: 14 LPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQ 193
+P+C + C L++P IV+FGESL D + + D+C+V+GTS V P A P
Sbjct: 175 VPYCTQ--CKGLVKPDIVFFGESLPADFFDNRD-LPEQADLCIVMGTSLQVQPFASL-PA 230
Query: 194 AASRGAIVAEFNIE 235
S G N+E
Sbjct: 231 FVSDGVPRVLINME 244
>UniRef50_Q899G3 Cluster: NAD-dependent deacetylase; n=19; cellular
organisms|Rep: NAD-dependent deacetylase - Clostridium
tetani
Length = 247
Score = 43.6 bits (98), Expect = 0.003
Identities = 22/57 (38%), Positives = 33/57 (57%)
Frame = +2
Query: 8 KLLPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAA 178
+++P C CG +++P +V + E L D + A + DV +V GTS VVYPAA
Sbjct: 147 EVVPKCDV--CGGIVKPDVVLYEEPLNMDNINNAVRYVENSDVLIVGGTSLVVYPAA 201
>UniRef50_Q0AY57 Cluster: Regulatory protein, sir2 family; n=1;
Syntrophomonas wolfei subsp. wolfei str. Goettingen|Rep:
Regulatory protein, sir2 family - Syntrophomonas wolfei
subsp. wolfei (strain Goettingen)
Length = 253
Score = 43.2 bits (97), Expect = 0.003
Identities = 24/79 (30%), Positives = 44/79 (55%)
Frame = +2
Query: 8 KLLPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFA 187
+++P C + CG +L+P +V FGE ++ + +A + + V +V+G+S VYP A F
Sbjct: 148 EVIPRCSQ--CGGILKPDVVLFGEHIK-NYPDAMDRILG-ARVLVVIGSSLTVYPLAGFV 203
Query: 188 PQAASRGAIVAEFNIEPTP 244
+ ++ + N PTP
Sbjct: 204 KEFSTFTQYLIIINKGPTP 222
>UniRef50_A2F9H1 Cluster: Transcriptional regulator, Sir2 family
protein; n=2; Trichomonas vaginalis|Rep: Transcriptional
regulator, Sir2 family protein - Trichomonas vaginalis
G3
Length = 304
Score = 43.2 bits (97), Expect = 0.003
Identities = 20/53 (37%), Positives = 28/53 (52%)
Frame = +2
Query: 20 HCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAA 178
HC C ++P IV+FGE+L A + +CD+ L+ GTS V P A
Sbjct: 166 HCTDPDCKGFIKPDIVFFGENLPTSFQHNARIDLRSCDMLLISGTSLKVNPFA 218
>UniRef50_Q89LY4 Cluster: NAD-dependent deacetylase 1; n=12;
Proteobacteria|Rep: NAD-dependent deacetylase 1 -
Bradyrhizobium japonicum
Length = 254
Score = 43.2 bits (97), Expect = 0.003
Identities = 23/75 (30%), Positives = 38/75 (50%)
Frame = +2
Query: 17 PHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQA 196
P+C C ++ + FG+ + + ++ A CD+ + +G+S VV+PAA F A
Sbjct: 158 PNCTV--CDEPVKTATISFGQMMPEEEMQRATALSRACDLFIAIGSSLVVWPAAGFPMMA 215
Query: 197 ASRGAIVAEFNIEPT 241
GA + N EPT
Sbjct: 216 KRAGARLVIINREPT 230
>UniRef50_A7H7B6 Cluster: Silent information regulator protein Sir2;
n=2; Anaeromyxobacter|Rep: Silent information regulator
protein Sir2 - Anaeromyxobacter sp. Fw109-5
Length = 270
Score = 42.7 bits (96), Expect = 0.005
Identities = 24/71 (33%), Positives = 35/71 (49%), Gaps = 2/71 (2%)
Frame = +2
Query: 38 CGALLRPHIVWFGESLE--HDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQAASRGA 211
CG LRPH++WF E + + +E+A A + ++ LVVGTS A R A
Sbjct: 169 CGGWLRPHVLWFDEYYDEVNYRMESALRAAAEAELLLVVGTSGATNLPMQIGRLAFERQA 228
Query: 212 IVAEFNIEPTP 244
+ + N E P
Sbjct: 229 ALVDVNPEVNP 239
>UniRef50_A3ZMQ7 Cluster: Sir2 family, possible ADP
ribosyltransferase; n=1; Blastopirellula marina DSM
3645|Rep: Sir2 family, possible ADP ribosyltransferase -
Blastopirellula marina DSM 3645
Length = 252
Score = 42.7 bits (96), Expect = 0.005
Identities = 31/94 (32%), Positives = 39/94 (41%)
Frame = +2
Query: 14 LPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQ 193
+P C G L + V FG+ L D+LE A S D+ L +G+S VV PAA
Sbjct: 151 VPPCPNCETGRL-KHATVSFGQMLPTDVLETAYDWCSDADLILAIGSSLVVTPAADLPVA 209
Query: 194 AASRGAIVAEFNIEPTPATPDFHFYFEGPCGTTL 295
RG V N + T G G TL
Sbjct: 210 VRRRGGRVVILNRDETGLDQIADAKLSGGIGATL 243
>UniRef50_Q6C8V5 Cluster: Similar to tr|Q9FY91 Arabidopsis thaliana
SIR2-family protein; n=1; Yarrowia lipolytica|Rep:
Similar to tr|Q9FY91 Arabidopsis thaliana SIR2-family
protein - Yarrowia lipolytica (Candida lipolytica)
Length = 411
Score = 42.7 bits (96), Expect = 0.005
Identities = 25/72 (34%), Positives = 36/72 (50%)
Frame = +2
Query: 14 LPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQ 193
+P C +CG +L+P IV+FGES+ A + + D LV+GTS + A Q
Sbjct: 312 IPPC--LNCGGVLKPSIVFFGESVPEADRARARDLLESSDQLLVIGTSLSTFSAFDLVRQ 369
Query: 194 AASRGAIVAEFN 229
+G VA N
Sbjct: 370 FYKQGKKVAVLN 381
>UniRef50_A1CD03 Cluster: SIR2 family histone deacetylase, putative;
n=2; Trichocomaceae|Rep: SIR2 family histone
deacetylase, putative - Aspergillus clavatus
Length = 329
Score = 42.7 bits (96), Expect = 0.005
Identities = 20/61 (32%), Positives = 35/61 (57%)
Frame = +2
Query: 11 LLPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAP 190
++P+C+ CG ++P +V+FG+SL + E E + D+ +V+GTS V P +
Sbjct: 155 VVPYCQVPDCGGPIKPDVVFFGQSLPAE-FEDEEKKVPEADLMIVMGTSLKVAPCSRLPG 213
Query: 191 Q 193
Q
Sbjct: 214 Q 214
>UniRef50_A6G0H3 Cluster: Silent information regulator protein Sir2;
n=1; Plesiocystis pacifica SIR-1|Rep: Silent information
regulator protein Sir2 - Plesiocystis pacifica SIR-1
Length = 288
Score = 42.3 bits (95), Expect = 0.006
Identities = 22/70 (31%), Positives = 33/70 (47%), Gaps = 2/70 (2%)
Frame = +2
Query: 41 GALLRPHIVWFGESLEHDIL--EAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQAASRGAI 214
G RPH++WF E E ++ ++A A CD+ +VVGTS + A R A
Sbjct: 183 GRRTRPHVLWFDEYYEEELFRSDSALRAAGECDLIVVVGTSGAAAIPYHMSAAALERDAA 242
Query: 215 VAEFNIEPTP 244
+ + N P
Sbjct: 243 IIDINPGQNP 252
>UniRef50_A2DP91 Cluster: Transcriptional regulator, Sir2 family
protein; n=1; Trichomonas vaginalis G3|Rep:
Transcriptional regulator, Sir2 family protein -
Trichomonas vaginalis G3
Length = 267
Score = 42.3 bits (95), Expect = 0.006
Identities = 23/79 (29%), Positives = 37/79 (46%), Gaps = 2/79 (2%)
Frame = +2
Query: 38 CGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQAASRGAIV 217
C + LRP + +F + + + + A T D+ +++GT VV P +A GA V
Sbjct: 158 CNSNLRPTVAFFQDLIPKALRQKATKICQTTDLLILIGTHCVVDPVVTLVAEAFQSGATV 217
Query: 218 AEFNIEPTPATP--DFHFY 268
E N + T + D FY
Sbjct: 218 VEINPDETRISDKCDMKFY 236
>UniRef50_Q7SCL4 Cluster: Putative uncharacterized protein NCU00523.1;
n=2; Pezizomycotina|Rep: Putative uncharacterized protein
NCU00523.1 - Neurospora crassa
Length = 1220
Score = 42.3 bits (95), Expect = 0.006
Identities = 22/55 (40%), Positives = 32/55 (58%)
Frame = +2
Query: 14 LPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAA 178
+PHC+K C L++P IV+F E+L + H D+ LV+GTS V+P A
Sbjct: 1017 VPHCEK--CNGLVKPDIVFFHENLPSLFFDR-RHMAEEADLILVLGTSLTVHPFA 1068
>UniRef50_A2GAR7 Cluster: Transcriptional regulator, Sir2 family
protein; n=1; Trichomonas vaginalis G3|Rep:
Transcriptional regulator, Sir2 family protein -
Trichomonas vaginalis G3
Length = 312
Score = 41.9 bits (94), Expect = 0.008
Identities = 22/79 (27%), Positives = 39/79 (49%)
Frame = +2
Query: 20 HCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQAA 199
HC++ G +++P +V++GE L +E+ ST ++ +++GTS V P M P
Sbjct: 175 HCRECKEG-VIKPDVVFYGEDLPQRFHHLSENDFSTANLLIIMGTSLTVSPCCML-PGYC 232
Query: 200 SRGAIVAEFNIEPTPATPD 256
+ N EP P+
Sbjct: 233 PPNCVRVLINNEPAGKCPE 251
>UniRef50_O94066 Cluster: Transcription regulatory protein; n=6;
Saccharomycetales|Rep: Transcription regulatory protein
- Candida albicans (Yeast)
Length = 331
Score = 41.9 bits (94), Expect = 0.008
Identities = 21/57 (36%), Positives = 30/57 (52%)
Frame = +2
Query: 8 KLLPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAA 178
K +P C+ HC ++P IV+FGE L + E +V +V GTS V+P A
Sbjct: 156 KKIPSCQ--HCEGYVKPDIVFFGEGLPVKFFDLWEDDCEDVEVAIVAGTSLTVFPFA 210
>UniRef50_Q046W9 Cluster: NAD-dependent protein deacetylase, SIR2
family; n=6; Lactobacillus|Rep: NAD-dependent protein
deacetylase, SIR2 family - Lactobacillus gasseri (strain
ATCC 33323 / DSM 20243)
Length = 237
Score = 41.5 bits (93), Expect = 0.011
Identities = 26/70 (37%), Positives = 37/70 (52%), Gaps = 1/70 (1%)
Frame = +2
Query: 47 LLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQAASRGAIVAEF 226
++RP IV +GE + +L + A+ D+ ++ GTS VVYP FA A R A +
Sbjct: 152 IIRPGIVLYGEPINEMVLTDSVKAIQNSDLVIIAGTSFVVYP---FAQLLAYRQATAKVW 208
Query: 227 NIEPTPA-TP 253
I TP TP
Sbjct: 209 VINNTPVPTP 218
>UniRef50_A0Z2E4 Cluster: NAD-dependent deacetylase; n=1; marine
gamma proteobacterium HTCC2080|Rep: NAD-dependent
deacetylase - marine gamma proteobacterium HTCC2080
Length = 288
Score = 41.5 bits (93), Expect = 0.011
Identities = 17/56 (30%), Positives = 32/56 (57%)
Frame = +2
Query: 38 CGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQAASR 205
CG +L+P +V+FG ++ + + + A++ D LV+G+S V+ F QA +
Sbjct: 181 CGGMLKPDVVFFGGTIPRERVTRCQEALTAADGLLVIGSSLQVFSGFRFCRQAVEQ 236
>UniRef50_Q4QB33 Cluster: Sir2-family protein-like protein; n=4;
Trypanosomatidae|Rep: Sir2-family protein-like protein -
Leishmania major
Length = 320
Score = 41.5 bits (93), Expect = 0.011
Identities = 25/69 (36%), Positives = 34/69 (49%), Gaps = 1/69 (1%)
Frame = +2
Query: 38 CGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLV-VGTSSVVYPAAMFAPQAASRGAI 214
C +PH+V FGE++ I+EA + CL+ +GTS VY A + QA G
Sbjct: 210 CNGFFKPHVVLFGENVPKPIVEATMSLVRDKASCLLCLGTSLQVYSAYRYVLQANQLGIP 269
Query: 215 VAEFNIEPT 241
VA N T
Sbjct: 270 VAIVNAGTT 278
>UniRef50_Q4WET3 Cluster: SIR2 family histone deacetylase, putative;
n=4; Pezizomycotina|Rep: SIR2 family histone
deacetylase, putative - Aspergillus fumigatus (Sartorya
fumigata)
Length = 381
Score = 41.5 bits (93), Expect = 0.011
Identities = 20/62 (32%), Positives = 34/62 (54%)
Frame = +2
Query: 47 LLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQAASRGAIVAEF 226
+L+P +V FGE+++ + AAE A+ L++G+S Y A +A RG +A
Sbjct: 276 ILKPAVVMFGENIDPGVKTAAEEAIDDAGRLLILGSSLATYSAWRLVERAHRRGMPIAII 335
Query: 227 NI 232
N+
Sbjct: 336 NL 337
>UniRef50_A7EC18 Cluster: Putative uncharacterized protein; n=1;
Sclerotinia sclerotiorum 1980|Rep: Putative
uncharacterized protein - Sclerotinia sclerotiorum 1980
Length = 446
Score = 41.5 bits (93), Expect = 0.011
Identities = 21/53 (39%), Positives = 31/53 (58%)
Frame = +2
Query: 23 CKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAM 181
C CG L++P IV+FGE L + + + +T D+ +V+GTS V P AM
Sbjct: 179 CLVPQCGGLVKPDIVFFGEQLP-EAFHSHKMIPATADLIIVMGTSLSVQPFAM 230
>UniRef50_A6RXY5 Cluster: Putative uncharacterized protein; n=2;
Pezizomycotina|Rep: Putative uncharacterized protein -
Botryotinia fuckeliana B05.10
Length = 446
Score = 41.1 bits (92), Expect = 0.014
Identities = 24/64 (37%), Positives = 34/64 (53%), Gaps = 3/64 (4%)
Frame = +2
Query: 23 CKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAA---MFAPQ 193
C CG L++P IV+FGE L + A + +T D+ +V+GTS V P A AP+
Sbjct: 179 CLVPQCGGLVKPDIVFFGEQLP-EAFHANKMIPATADLVIVMGTSLSVQPFATLPTLAPE 237
Query: 194 AASR 205
R
Sbjct: 238 TVPR 241
>UniRef50_Q96EB6 Cluster: NAD-dependent deacetylase sirtuin-1; n=29;
Euteleostomi|Rep: NAD-dependent deacetylase sirtuin-1 -
Homo sapiens (Human)
Length = 747
Score = 41.1 bits (92), Expect = 0.014
Identities = 23/76 (30%), Positives = 36/76 (47%)
Frame = +2
Query: 17 PHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQA 196
P C A+++P IV+FGE+L A ++ D+ +V+G+S V P A+ P +
Sbjct: 396 PRCPADEPLAIMKPEIVFFGENLPEQFHRAMKYDKDEVDLLIVIGSSLKVRPVALI-PSS 454
Query: 197 ASRGAIVAEFNIEPTP 244
N EP P
Sbjct: 455 IPHEVPQILINREPLP 470
>UniRef50_UPI0000D55B5A Cluster: PREDICTED: similar to CG5216-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG5216-PA - Tribolium castaneum
Length = 722
Score = 40.7 bits (91), Expect = 0.019
Identities = 23/66 (34%), Positives = 33/66 (50%)
Frame = +2
Query: 47 LLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQAASRGAIVAEF 226
+++P IV+FGE L EA + CD+ LV+G+S V P A+ P +
Sbjct: 386 IMKPDIVFFGEGLPDTFHEAMAQDKTECDLLLVIGSSLKVRPVALI-PSSLPPHVPQILI 444
Query: 227 NIEPTP 244
N EP P
Sbjct: 445 NREPLP 450
>UniRef50_A5UYK2 Cluster: Silent information regulator protein Sir2;
n=2; Roseiflexus|Rep: Silent information regulator
protein Sir2 - Roseiflexus sp. RS-1
Length = 261
Score = 40.7 bits (91), Expect = 0.019
Identities = 26/91 (28%), Positives = 35/91 (38%)
Frame = +2
Query: 29 KAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQAASRG 208
+ CG L+P +V F E L + A A+ DV +V GTS V+P G
Sbjct: 156 RCSCGHPLKPDVVLFDEMLPRGLYWLARRAVEHADVIIVAGTSLEVFPVNDLPALGLRHG 215
Query: 209 AIVAEFNIEPTPATPDFHFYFEGPCGTTLPQ 301
A + N PT G LP+
Sbjct: 216 AKLIIINNGPTYLDGRAEAVIRGDVAIALPE 246
>UniRef50_Q7JMD3 Cluster: Putative uncharacterized protein sir-2.2;
n=4; Caenorhabditis|Rep: Putative uncharacterized
protein sir-2.2 - Caenorhabditis elegans
Length = 289
Score = 40.7 bits (91), Expect = 0.019
Identities = 23/78 (29%), Positives = 36/78 (46%)
Frame = +2
Query: 14 LPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQ 193
+P C CG L++ + +FGE++ D + ++ CD L +GTS V F
Sbjct: 195 IPECPS--CGGLMKTDVTFFGENVNMDKVNFCYEKVNECDGILSLGTSLAVLSGFRFIHH 252
Query: 194 AASRGAIVAEFNIEPTPA 247
A + + NI PT A
Sbjct: 253 ANMKKKPIFIVNIGPTRA 270
>UniRef50_Q4DP02 Cluster: Silent information regulator 2, putative;
n=4; Trypanosoma|Rep: Silent information regulator 2,
putative - Trypanosoma cruzi
Length = 359
Score = 40.7 bits (91), Expect = 0.019
Identities = 21/58 (36%), Positives = 35/58 (60%)
Frame = +2
Query: 14 LPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFA 187
+PHC + CG +++P +V+FGESL D ++ ++ L++GTS V+P A A
Sbjct: 171 VPHCDR--CGGVVKPDVVFFGESLP-DAFFNVFAEITEVELLLIMGTSLQVHPFAELA 225
>UniRef50_Q298C7 Cluster: GA18650-PA; n=1; Drosophila
pseudoobscura|Rep: GA18650-PA - Drosophila pseudoobscura
(Fruit fly)
Length = 381
Score = 40.7 bits (91), Expect = 0.019
Identities = 19/58 (32%), Positives = 32/58 (55%)
Frame = +2
Query: 14 LPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFA 187
LP C C +++P IV+FGE+L + + CD+ +++GT+ V+P A A
Sbjct: 215 LPTCTS--CKKIVKPDIVFFGENLPEKFHNSLDGDFKECDLLIIMGTTLEVHPFASLA 270
>UniRef50_A2QUR5 Cluster: Remark: the H. sapiens SIRT4 belongs to a
group of four human SIRT proteins; n=1; Aspergillus
niger|Rep: Remark: the H. sapiens SIRT4 belongs to a
group of four human SIRT proteins - Aspergillus niger
Length = 357
Score = 40.7 bits (91), Expect = 0.019
Identities = 22/72 (30%), Positives = 36/72 (50%)
Frame = +2
Query: 17 PHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQA 196
P C + G +L+P ++ FGE+++ + AE A+ LV+G+S Y A +A
Sbjct: 240 PACPTSTAG-ILKPAVIMFGENIDPAVRLGAEEAIDDAGRLLVLGSSLATYSAWRLVERA 298
Query: 197 ASRGAIVAEFNI 232
RG + NI
Sbjct: 299 YKRGMPIGIINI 310
>UniRef50_Q3V7G9 Cluster: Putative cobalamin biosynthetic protein;
n=2; Acinetobacter|Rep: Putative cobalamin biosynthetic
protein - Acinetobacter sp. (strain ADP1)
Length = 233
Score = 40.3 bits (90), Expect = 0.024
Identities = 20/50 (40%), Positives = 30/50 (60%)
Frame = +2
Query: 29 KAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAA 178
K + G LRPH+VWFGE++ + A + DV +V+G++ VYP A
Sbjct: 137 KCNEGYPLRPHVVWFGEAV--PAYDDAIAMLKDADVFIVIGSTLSVYPVA 184
>UniRef50_Q9FY91 Cluster: SIR2-family protein; n=12;
Magnoliophyta|Rep: SIR2-family protein - Arabidopsis
thaliana (Mouse-ear cress)
Length = 451
Score = 40.3 bits (90), Expect = 0.024
Identities = 23/78 (29%), Positives = 38/78 (48%)
Frame = +2
Query: 14 LPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQ 193
+P C+K C +L+P +++FG+++ + A D LV+G+S + A
Sbjct: 346 IPVCEK--CKGVLKPDVIFFGDNIPKERATQAMEVAKQSDAFLVLGSSLMTMSAFRLCRA 403
Query: 194 AASRGAIVAEFNIEPTPA 247
A GA+ A NI T A
Sbjct: 404 AHEAGAMTAIVNIGETRA 421
>UniRef50_A7RLD5 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 335
Score = 40.3 bits (90), Expect = 0.024
Identities = 20/55 (36%), Positives = 30/55 (54%)
Frame = +2
Query: 14 LPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAA 178
+P C+ C +++P +V+FGE L + E CD+ LV+GTS V P A
Sbjct: 135 IPRCETIKCKGVIKPDVVFFGEDLPKRFY-SFEIDFRKCDLLLVMGTSLEVEPFA 188
>UniRef50_Q5KDE0 Cluster: NAD-dependent histone deacetylase,
putative; n=2; Filobasidiella neoformans|Rep:
NAD-dependent histone deacetylase, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 413
Score = 40.3 bits (90), Expect = 0.024
Identities = 20/51 (39%), Positives = 28/51 (54%)
Frame = +2
Query: 26 KKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAA 178
K CG L++P IV+FGE L + + CD+ +V+GTS V P A
Sbjct: 225 KGKKCGGLVKPDIVFFGEGLPDRFFKLVPE-LRKCDLLIVIGTSLQVQPFA 274
>UniRef50_O07595 Cluster: NAD-dependent deacetylase; n=3;
Bacillus|Rep: NAD-dependent deacetylase - Bacillus
subtilis
Length = 247
Score = 40.3 bits (90), Expect = 0.024
Identities = 25/70 (35%), Positives = 37/70 (52%), Gaps = 2/70 (2%)
Frame = +2
Query: 38 CGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQAAS--RGA 211
CG +L+ +V FG+++ H + + D+ LV+GTS V P A F P+ AS G
Sbjct: 156 CGTVLKTDVVLFGDAVMH--FDTLYEKLDQADLLLVIGTSLEVAP-ARFVPEDASLIPGM 212
Query: 212 IVAEFNIEPT 241
N+EPT
Sbjct: 213 KKVIINLEPT 222
>UniRef50_Q9RL35 Cluster: NAD-dependent deacetylase 1; n=8;
Actinomycetales|Rep: NAD-dependent deacetylase 1 -
Streptomyces coelicolor
Length = 299
Score = 40.3 bits (90), Expect = 0.024
Identities = 23/70 (32%), Positives = 34/70 (48%)
Frame = +2
Query: 32 AHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQAASRGA 211
A CG +L+P +V+FGE++ +E + LV+G+S V F QAA G
Sbjct: 195 AVCGGVLKPDVVFFGENVPPRRVEHCRELVRGASSLLVLGSSLTVMSGLRFVRQAAEAGK 254
Query: 212 IVAEFNIEPT 241
V N + T
Sbjct: 255 PVLIVNRDAT 264
>UniRef50_A6TNA0 Cluster: Silent information regulator protein Sir2;
n=1; Alkaliphilus metalliredigens QYMF|Rep: Silent
information regulator protein Sir2 - Alkaliphilus
metalliredigens QYMF
Length = 249
Score = 39.9 bits (89), Expect = 0.032
Identities = 17/41 (41%), Positives = 26/41 (63%)
Frame = +2
Query: 50 LRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYP 172
LRP ++ FGE+L ++A + CD+ +V+GTS VYP
Sbjct: 162 LRPSVILFGETLPPKAWDSALRDIQKCDLLIVIGTSLEVYP 202
>UniRef50_A6XDL2 Cluster: Sirtuin 1; n=2; Schistosoma|Rep: Sirtuin 1
- Schistosoma mansoni (Blood fluke)
Length = 568
Score = 39.9 bits (89), Expect = 0.032
Identities = 25/79 (31%), Positives = 39/79 (49%)
Frame = +2
Query: 47 LLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQAASRGAIVAEF 226
+L+P IV+FGE L ++ ++ + + D+ LV+G+S V P + P A R
Sbjct: 367 VLKPDIVFFGEGLSNEFHDSLSNDIKQTDLVLVIGSSLKVRPVS-HIPNAVPRQVPQILI 425
Query: 227 NIEPTPATPDFHFYFEGPC 283
N EP + DF G C
Sbjct: 426 NREPL-SNHDFDVELLGDC 443
>UniRef50_Q21921 Cluster: NAD-dependent deacetylase SIR2 homolog;
n=2; Caenorhabditis|Rep: NAD-dependent deacetylase SIR2
homolog - Caenorhabditis elegans
Length = 607
Score = 39.9 bits (89), Expect = 0.032
Identities = 22/75 (29%), Positives = 36/75 (48%)
Frame = +2
Query: 20 HCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQAA 199
HCK+ C +++P+IV+FGE L + + D+ +V+G+S V P A+ P
Sbjct: 286 HCKR--CEGVIKPNIVFFGEDLGREFHQHVTEDKHKVDLIVVIGSSLKVRPVALI-PHCV 342
Query: 200 SRGAIVAEFNIEPTP 244
+ N E P
Sbjct: 343 DKNVPQILINRESLP 357
>UniRef50_A1ZHW6 Cluster: NAD-dependent deacetylase; n=2;
Microscilla marina ATCC 23134|Rep: NAD-dependent
deacetylase - Microscilla marina ATCC 23134
Length = 279
Score = 39.5 bits (88), Expect = 0.043
Identities = 19/42 (45%), Positives = 26/42 (61%), Gaps = 2/42 (4%)
Frame = +2
Query: 38 CGALLRPHIVWFGE--SLEHDILEAAEHAMSTCDVCLVVGTS 157
CGAL RPH++WF E + ++ E A H D+ +VVGTS
Sbjct: 176 CGALTRPHVLWFDEYYNEKYYKYETALHKNREADLLIVVGTS 217
>UniRef50_Q8IRR5 Cluster: CG3187-PC, isoform C; n=4; Diptera|Rep:
CG3187-PC, isoform C - Drosophila melanogaster (Fruit
fly)
Length = 312
Score = 39.5 bits (88), Expect = 0.043
Identities = 26/96 (27%), Positives = 41/96 (42%)
Frame = +2
Query: 14 LPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQ 193
+P C + CG L+P IV+FG+S+ ++ + D LV+G+S +V+ Q
Sbjct: 208 IPECTQ--CGGDLKPEIVFFGDSVPRPRVDQIAGMVYNSDGLLVLGSSLLVFSGYRVVLQ 265
Query: 194 AASRGAIVAEFNIEPTPATPDFHFYFEGPCGTTLPQ 301
V NI T A CG +P+
Sbjct: 266 TKDLKLPVGIVNIGETRADHLADIKISAKCGDVIPK 301
>UniRef50_A0DQW0 Cluster: Chromosome undetermined scaffold_6, whole
genome shotgun sequence; n=3; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_6,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 367
Score = 39.5 bits (88), Expect = 0.043
Identities = 27/78 (34%), Positives = 37/78 (47%), Gaps = 2/78 (2%)
Frame = +2
Query: 11 LLPHCKKAHCGALLRPHIVWFGESL--EHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMF 184
L P C K CG RPHI++F ES E+ ++ + T D +VVGT A
Sbjct: 269 LRPKCPK--CGEDARPHILFFDESYTNENCRIQELQEKYETYDTIIVVGTMLETGCAKST 326
Query: 185 APQAASRGAIVAEFNIEP 238
+ + AI+ E N EP
Sbjct: 327 VCKFIKKKAIIIEINPEP 344
>UniRef50_O25849 Cluster: NAD-dependent deacetylase; n=11;
Bacteria|Rep: NAD-dependent deacetylase - Helicobacter
pylori (Campylobacter pylori)
Length = 229
Score = 39.5 bits (88), Expect = 0.043
Identities = 19/43 (44%), Positives = 28/43 (65%)
Frame = +2
Query: 50 LRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAA 178
LRP IVWFGE++ +L+ A + + +++GTS VYPAA
Sbjct: 138 LRPDIVWFGEAV--PLLKEAISLVKQAHLLIIIGTSLQVYPAA 178
>UniRef50_Q8IXJ6 Cluster: NAD-dependent deacetylase sirtuin-2; n=31;
Coelomata|Rep: NAD-dependent deacetylase sirtuin-2 -
Homo sapiens (Human)
Length = 389
Score = 39.1 bits (87), Expect = 0.057
Identities = 22/63 (34%), Positives = 33/63 (52%)
Frame = +2
Query: 8 KLLPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFA 187
++ P C+ C +L++P IV+FGESL + D+ LV+GTS V P A
Sbjct: 216 EVTPKCED--CQSLVKPDIVFFGESLPARFFSCMQSDFLKVDLLLVMGTSLQVQPFASLI 273
Query: 188 PQA 196
+A
Sbjct: 274 SKA 276
>UniRef50_Q839C6 Cluster: NAD-dependent deacetylase; n=14;
Bacilli|Rep: NAD-dependent deacetylase - Enterococcus
faecalis (Streptococcus faecalis)
Length = 237
Score = 39.1 bits (87), Expect = 0.057
Identities = 24/82 (29%), Positives = 38/82 (46%)
Frame = +2
Query: 26 KKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQAASR 205
+ A C +RP I + E L + +E A A+++ D+ ++VGTS V+P
Sbjct: 143 RHADCHGQIRPAITLYEEGLSEEAIEKAIQAVASADLIVIVGTSFQVHPFCDLIHYKQPT 202
Query: 206 GAIVAEFNIEPTPATPDFHFYF 271
I+A I TP +YF
Sbjct: 203 ATILA---INQTPLFLQQPYYF 221
>UniRef50_Q8R984 Cluster: NAD-dependent deacetylase 2; n=1;
Thermoanaerobacter tengcongensis|Rep: NAD-dependent
deacetylase 2 - Thermoanaerobacter tengcongensis
Length = 250
Score = 39.1 bits (87), Expect = 0.057
Identities = 19/52 (36%), Positives = 30/52 (57%)
Frame = +2
Query: 17 PHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYP 172
P C + CG +LRP +V FG+ + H + A + D+ +V+G+S VV P
Sbjct: 156 PRCDR--CGGMLRPDVVLFGDPMPH-AFDLALKEVQESDLLIVIGSSLVVAP 204
>UniRef50_UPI000050FCF4 Cluster: COG0846: NAD-dependent protein
deacetylases, SIR2 family; n=1; Brevibacterium linens
BL2|Rep: COG0846: NAD-dependent protein deacetylases,
SIR2 family - Brevibacterium linens BL2
Length = 309
Score = 38.7 bits (86), Expect = 0.075
Identities = 21/68 (30%), Positives = 32/68 (47%)
Frame = +2
Query: 38 CGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQAASRGAIV 217
CG +L+P +V+FG+S+ L+ A + +V+G+S V F AA G V
Sbjct: 207 CGGILKPDVVYFGDSVPPARLQEANRICAEASGIVVLGSSLAVLSGLRFVRAAAKAGKPV 266
Query: 218 AEFNIEPT 241
PT
Sbjct: 267 VIVTDGPT 274
>UniRef50_Q22KA8 Cluster: Transcriptional regulator, Sir2 family
protein; n=3; Tetrahymena thermophila SB210|Rep:
Transcriptional regulator, Sir2 family protein -
Tetrahymena thermophila SB210
Length = 386
Score = 38.7 bits (86), Expect = 0.075
Identities = 25/74 (33%), Positives = 33/74 (44%)
Frame = +2
Query: 23 CKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQAAS 202
C CG L IV FGE+L +E D+ LV+G+S V PAA A
Sbjct: 171 CDNQKCGGELVDTIVNFGENLPKKDMEQGFFNSKQADLHLVLGSSLRVTPAADMPLATAQ 230
Query: 203 RGAIVAEFNIEPTP 244
G + N++ TP
Sbjct: 231 NGNKLVVVNLQKTP 244
>UniRef50_Q2U9Y7 Cluster: Sirtuin 4 and related class II sirtuins;
n=10; Pezizomycotina|Rep: Sirtuin 4 and related class II
sirtuins - Aspergillus oryzae
Length = 407
Score = 38.3 bits (85), Expect = 0.099
Identities = 18/62 (29%), Positives = 33/62 (53%)
Frame = +2
Query: 47 LLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQAASRGAIVAEF 226
+L+P ++ FGE+++ + AAE A+ L++G+S + A +A RG +
Sbjct: 303 VLKPAVIMFGENIQPAVKTAAEEAIDDAGRLLILGSSLATFSAWRLVERAHKRGMPIGII 362
Query: 227 NI 232
NI
Sbjct: 363 NI 364
>UniRef50_A3LN35 Cluster: NAD-dependent histone deacetylase SIR2;
n=1; Pichia stipitis|Rep: NAD-dependent histone
deacetylase SIR2 - Pichia stipitis (Yeast)
Length = 391
Score = 38.3 bits (85), Expect = 0.099
Identities = 25/79 (31%), Positives = 34/79 (43%)
Frame = +2
Query: 47 LLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQAASRGAIVAEF 226
+++P I +FGE L E TCD+ +VVGTS V P + + R
Sbjct: 268 VIKPDITFFGEDLPKKFYRLLEPDCQTCDLVIVVGTSLKVEPVSSIIDK-IPRSVPRVLI 326
Query: 227 NIEPTPATPDFHFYFEGPC 283
N +P P DF G C
Sbjct: 327 NKDPIP-DRDFDLSLIGLC 344
>UniRef50_UPI00006CA40C Cluster: transcriptional regulator, Sir2
family protein; n=1; Tetrahymena thermophila SB210|Rep:
transcriptional regulator, Sir2 family protein -
Tetrahymena thermophila SB210
Length = 471
Score = 37.9 bits (84), Expect = 0.13
Identities = 19/53 (35%), Positives = 33/53 (62%)
Frame = +2
Query: 20 HCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAA 178
+CK+ G +++P IV+FGESL + + +++ D+ V+GTS V+P A
Sbjct: 353 YCKECEEG-IVKPDIVFFGESLPQSFFQQID-SLNKADLVFVMGTSLKVFPFA 403
>UniRef50_A1ZPG8 Cluster: NAD-dependent deacetylase; n=1;
Microscilla marina ATCC 23134|Rep: NAD-dependent
deacetylase - Microscilla marina ATCC 23134
Length = 278
Score = 37.9 bits (84), Expect = 0.13
Identities = 30/96 (31%), Positives = 41/96 (42%), Gaps = 8/96 (8%)
Frame = +2
Query: 38 CGALLRPHIVWFGESLEHDIL--EAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQAASRGA 211
CG+L+RP+++ F E + E+A A V VVGTS A A RG+
Sbjct: 175 CGSLMRPNVLMFDEYYNERLYKQESAIEAALNTGVLFVVGTSGATNLPHHIASTATYRGS 234
Query: 212 IVAEFNIEPTPAT------PDFHFYFEGPCGTTLPQ 301
+ + NI + T PD G G LPQ
Sbjct: 235 SLVDINIADSAFTDMATSEPD-KLVLRGTSGDILPQ 269
>UniRef50_Q480E0 Cluster: Putative membrane protein; n=1; Colwellia
psychrerythraea 34H|Rep: Putative membrane protein -
Colwellia psychrerythraea (strain 34H / ATCC BAA-681)
(Vibriopsychroerythus)
Length = 512
Score = 37.5 bits (83), Expect = 0.17
Identities = 17/59 (28%), Positives = 30/59 (50%)
Frame = +2
Query: 20 HCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQA 196
HC+ HC LL+P I+ E+++ + +A + M C LV+G ++ +M A
Sbjct: 401 HCQ--HCSGLLKPQILAADENIDSECYQALQKNMMECGCLLVIGVPTITPVVSMIIENA 457
>UniRef50_UPI000051AA14 Cluster: PREDICTED: similar to NAD-dependent
deacetylase sirtuin-1 (hSIRT1) (hSIR2) (SIR2-like
protein 1); n=1; Apis mellifera|Rep: PREDICTED: similar
to NAD-dependent deacetylase sirtuin-1 (hSIRT1) (hSIR2)
(SIR2-like protein 1) - Apis mellifera
Length = 868
Score = 37.1 bits (82), Expect = 0.23
Identities = 19/56 (33%), Positives = 30/56 (53%)
Frame = +2
Query: 14 LPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAM 181
+P C K +++P IV+FGE L +A CD+ +V+G+S V P A+
Sbjct: 342 IPLCPKC----IMKPDIVFFGEGLPDAFHDAMAKDKDECDLLIVIGSSLKVRPVAL 393
>UniRef50_A0JXS0 Cluster: Silent information regulator protein Sir2
precursor; n=11; Actinomycetales|Rep: Silent information
regulator protein Sir2 precursor - Arthrobacter sp.
(strain FB24)
Length = 306
Score = 37.1 bits (82), Expect = 0.23
Identities = 21/73 (28%), Positives = 33/73 (45%)
Frame = +2
Query: 11 LLPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAP 190
++ HC CG L+P V+FGE++ D +E + + +V G+S V F
Sbjct: 204 VVAHCPA--CGGTLKPDFVYFGENVPKDRVERSYAMVDEAGALVVAGSSLTVMSGLRFVR 261
Query: 191 QAASRGAIVAEFN 229
AA + V N
Sbjct: 262 HAAKQEKPVVIIN 274
>UniRef50_Q3F1F4 Cluster: SIR2 family protein; n=1; Bacillus
thuringiensis serovar israelensis ATCC 35646|Rep: SIR2
family protein - Bacillus thuringiensis serovar
israelensis ATCC 35646
Length = 241
Score = 36.7 bits (81), Expect = 0.30
Identities = 17/45 (37%), Positives = 25/45 (55%)
Frame = +2
Query: 38 CGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYP 172
C ++RP +V FGE+L A M D+ +V+GTS V+P
Sbjct: 148 CTGVVRPEVVLFGETLPPLAWHQANEQMKKTDLVIVLGTSLQVFP 192
>UniRef50_A4A8B4 Cluster: Silent information regulator protein Sir2;
n=1; Congregibacter litoralis KT71|Rep: Silent
information regulator protein Sir2 - Congregibacter
litoralis KT71
Length = 297
Score = 36.7 bits (81), Expect = 0.30
Identities = 23/70 (32%), Positives = 31/70 (44%)
Frame = +2
Query: 38 CGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQAASRGAIV 217
C L P +V+FG S+ +E + + + LVVG+S VY F AA G V
Sbjct: 186 CDGTLMPDVVFFGGSIPGSRVEQCKQVLEHSNSVLVVGSSLQVYSGYRFCKWAAKAGKPV 245
Query: 218 AEFNIEPTPA 247
N T A
Sbjct: 246 FLMNPGQTRA 255
>UniRef50_UPI00015B57C0 Cluster: PREDICTED: similar to GA18743-PA;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
GA18743-PA - Nasonia vitripennis
Length = 871
Score = 36.3 bits (80), Expect = 0.40
Identities = 16/45 (35%), Positives = 26/45 (57%)
Frame = +2
Query: 47 LLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAM 181
+++P IV+FGE L +A CD+ +V+G+S V P A+
Sbjct: 374 VMKPDIVFFGEGLPDAFHDAMASDKDVCDLLIVIGSSLKVRPVAL 418
>UniRef50_Q9FE17 Cluster: Sir2-like protein; n=9; Magnoliophyta|Rep:
Sir2-like protein - Arabidopsis thaliana (Mouse-ear
cress)
Length = 473
Score = 35.9 bits (79), Expect = 0.53
Identities = 19/74 (25%), Positives = 34/74 (45%)
Frame = +2
Query: 23 CKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQAAS 202
C CGA L+ ++ + ++L ++ AE D+ L +GTS + PA +
Sbjct: 167 CSVEKCGAKLKDTVLDWEDALPPKEIDPAEKHCKKADLVLCLGTSLQITPACNLPLKCLK 226
Query: 203 RGAIVAEFNIEPTP 244
G + N++ TP
Sbjct: 227 GGGKIVIVNLQKTP 240
>UniRef50_A2DZ29 Cluster: Transcriptional regulator, Sir2 family
protein; n=4; Trichomonas vaginalis|Rep: Transcriptional
regulator, Sir2 family protein - Trichomonas vaginalis
G3
Length = 375
Score = 35.9 bits (79), Expect = 0.53
Identities = 20/55 (36%), Positives = 31/55 (56%)
Frame = +2
Query: 14 LPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAA 178
+P C CG ++P IV+FG+S+ + E E+ D+ LV+GTS V P +
Sbjct: 226 VPRC--IFCGGAIKPGIVFFGQSVNLNDFE-LENDAREADLLLVIGTSLRVAPVS 277
>UniRef50_Q885X7 Cluster: NAD-dependent deacetylase 2; n=4;
Pseudomonas|Rep: NAD-dependent deacetylase 2 -
Pseudomonas syringae pv. tomato
Length = 248
Score = 35.9 bits (79), Expect = 0.53
Identities = 28/80 (35%), Positives = 40/80 (50%), Gaps = 3/80 (3%)
Frame = +2
Query: 11 LLPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMST-CDVCLVVGTSSVVYPAAMFA 187
L P C+ CG +LRP +V F E L LE ++T D L +GT++ +P +
Sbjct: 148 LPPLCRL--CGGILRPPVVLFQEMLPERALETLYEQLATGYDAVLSIGTTA-SFP-YIHE 203
Query: 188 PQAASR--GAIVAEFNIEPT 241
P +R G AE N +PT
Sbjct: 204 PVIRTRVSGGFTAEINPQPT 223
>UniRef50_Q6AF12 Cluster: Regulatory protein, Sir2 family; n=2;
Actinobacteria (class)|Rep: Regulatory protein, Sir2
family - Leifsonia xyli subsp. xyli
Length = 283
Score = 35.5 bits (78), Expect = 0.70
Identities = 18/65 (27%), Positives = 31/65 (47%)
Frame = +2
Query: 11 LLPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAP 190
++P C CG L+P +V+FGE + + A + + D ++ G+S VV
Sbjct: 183 VIPDCTV--CGERLKPDVVFFGEFIPAETYREASALVRSADALVIAGSSLVVNSGVRLLE 240
Query: 191 QAASR 205
+A R
Sbjct: 241 EARRR 245
>UniRef50_Q7QZ36 Cluster: GLP_464_21655_23334; n=1; Giardia lamblia
ATCC 50803|Rep: GLP_464_21655_23334 - Giardia lamblia
ATCC 50803
Length = 559
Score = 35.5 bits (78), Expect = 0.70
Identities = 15/44 (34%), Positives = 26/44 (59%)
Frame = +2
Query: 47 LLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAA 178
+L+P I++FGE L D+ E + S D+ + +G+S V P +
Sbjct: 414 ILKPQIIFFGEKLSSDLEEFIDDDCSVADMFIAIGSSLRVKPVS 457
>UniRef50_Q1RPU3 Cluster: Zinc finger protein; n=1; Ciona
intestinalis|Rep: Zinc finger protein - Ciona
intestinalis (Transparent sea squirt)
Length = 737
Score = 35.5 bits (78), Expect = 0.70
Identities = 17/60 (28%), Positives = 31/60 (51%), Gaps = 2/60 (3%)
Frame = +2
Query: 8 KLLPHCKKAHCG--ALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAM 181
+++PHC + +++P IV+FGE+L D+ +V+G+S V P A+
Sbjct: 325 QVVPHCPRCPSDDPGVIKPDIVFFGENLPQQFHRQMTSDKDDADLLIVIGSSLKVRPVAL 384
>UniRef50_A2DKF0 Cluster: Transcriptional regulator, Sir2 family
protein; n=1; Trichomonas vaginalis G3|Rep:
Transcriptional regulator, Sir2 family protein -
Trichomonas vaginalis G3
Length = 347
Score = 35.5 bits (78), Expect = 0.70
Identities = 27/85 (31%), Positives = 41/85 (48%), Gaps = 3/85 (3%)
Frame = +2
Query: 38 CGALLRPHIVWFGESL---EHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQAASRG 208
CG ++P IV+FG+ + DI +E D+ +V+GTS V P +M P+ S+
Sbjct: 209 CGGQIKPGIVFFGQKTNIEDEDITADSEEG----DLLIVIGTSLKVAPISML-PEFFSQ- 262
Query: 209 AIVAEFNIEPTPATPDFHFYFEGPC 283
+ I P T +F F G C
Sbjct: 263 --IPSILINREPVTCNFSAEFLGDC 285
>UniRef50_Q7S6G9 Cluster: Putative uncharacterized protein
NCU04737.1; n=3; Sordariomycetes|Rep: Putative
uncharacterized protein NCU04737.1 - Neurospora crassa
Length = 670
Score = 35.1 bits (77), Expect = 0.92
Identities = 18/52 (34%), Positives = 28/52 (53%), Gaps = 1/52 (1%)
Frame = +2
Query: 38 CGALLRPHIVWFGESLEHDI-LEAAEHAMSTCDVCLVVGTSSVVYPAAMFAP 190
CG +++P I +FGE+L + EH D+ +V+GTS V P + P
Sbjct: 422 CG-VMKPDITFFGEALPDEFSTRLTEHDRDLVDLVIVIGTSLKVAPVSEVVP 472
>UniRef50_Q4P1X1 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 434
Score = 35.1 bits (77), Expect = 0.92
Identities = 19/46 (41%), Positives = 26/46 (56%)
Frame = +2
Query: 41 GALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAA 178
G L++P IV+FGESL + T D+ +V+GTS V P A
Sbjct: 211 GGLVKPDIVFFGESLPPRFFRCIPD-LKTADLLIVMGTSLQVQPFA 255
>UniRef50_A4QX96 Cluster: Putative uncharacterized protein; n=2;
Magnaporthe grisea|Rep: Putative uncharacterized protein
- Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 534
Score = 35.1 bits (77), Expect = 0.92
Identities = 16/33 (48%), Positives = 20/33 (60%)
Frame = +2
Query: 14 LPHCKKAHCGALLRPHIVWFGESLEHDILEAAE 112
+PHC K CG L++P IV+FGE L A E
Sbjct: 175 VPHCGK--CGGLVKPDIVFFGEQLPDRFFRARE 205
>UniRef50_Q7QZ37 Cluster: GLP_464_19573_21615; n=1; Giardia lamblia
ATCC 50803|Rep: GLP_464_19573_21615 - Giardia lamblia
ATCC 50803
Length = 680
Score = 34.7 bits (76), Expect = 1.2
Identities = 20/53 (37%), Positives = 28/53 (52%), Gaps = 2/53 (3%)
Frame = +2
Query: 20 HCKKAHCGALLRPHIVWFGESLEHDILEAAE--HAMSTCDVCLVVGTSSVVYP 172
HC + CG +L+P IV+FGE L + A E + L++GTS V P
Sbjct: 171 HCPR--CGRVLKPRIVFFGEQLPSEFQLAPEIIGDAEKTSMLLILGTSLTVAP 221
>UniRef50_Q6C219 Cluster: Yarrowia lipolytica chromosome F of strain
CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome F of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 320
Score = 34.7 bits (76), Expect = 1.2
Identities = 31/98 (31%), Positives = 44/98 (44%), Gaps = 7/98 (7%)
Frame = +2
Query: 14 LPHCKKAHCGALLRPHIVWFGESL----EHDILEAAEHAMST--CDVCLVVGTSSVVYPA 175
+P C++ C +++P IV+FGE+L H + T D+ L +GTS V PA
Sbjct: 202 IPMCRRKRCEGVIKPDIVFFGEALPDRFRHMVRSDIIMGGPTPKVDLFLCLGTSLKVSPA 261
Query: 176 AMFAPQAASRGAIVAEFNIEPTPATPDFHFYFE-GPCG 286
A Q G N EP+ FYF+ CG
Sbjct: 262 CDIAKQ-VPLGVPRVYINREPSA-----RFYFDISLCG 293
>UniRef50_Q03ZB1 Cluster: NAD-dependent protein deacetylase, SIR2
family; n=3; Leuconostocaceae|Rep: NAD-dependent protein
deacetylase, SIR2 family - Leuconostoc mesenteroides
subsp. mesenteroides (strain ATCC 8293 /NCDO 523)
Length = 234
Score = 34.3 bits (75), Expect = 1.6
Identities = 27/70 (38%), Positives = 37/70 (52%)
Frame = +2
Query: 44 ALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQAASRGAIVAE 223
ALLRP I ++ E + D+ ++A + D+ ++VGTS VYP A Q AS V
Sbjct: 150 ALLRPRITFY-EEMPFDVKKSALWVRNA-DLIVIVGTSFKVYPFAGLL-QYASPAVPVMS 206
Query: 224 FNIEPTPATP 253
N E ATP
Sbjct: 207 INFERI-ATP 215
>UniRef50_Q1RL71 Cluster: Zinc finger protein; n=2; Ciona
intestinalis|Rep: Zinc finger protein - Ciona
intestinalis (Transparent sea squirt)
Length = 523
Score = 34.3 bits (75), Expect = 1.6
Identities = 22/63 (34%), Positives = 30/63 (47%), Gaps = 1/63 (1%)
Frame = +2
Query: 11 LLPHCKKAH-CGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFA 187
++P C+ C ++P IV+FGE L + S CD+ LV GTS V P A
Sbjct: 259 VIPRCQLTPLCYGTIKPDIVFFGEDLPKRFYYYLKDFPS-CDLLLVFGTSLQVEPFASLV 317
Query: 188 PQA 196
A
Sbjct: 318 DSA 320
>UniRef50_Q88ZA0 Cluster: NAD-dependent deacetylase; n=4;
Lactobacillus|Rep: NAD-dependent deacetylase -
Lactobacillus plantarum
Length = 234
Score = 34.3 bits (75), Expect = 1.6
Identities = 19/63 (30%), Positives = 31/63 (49%)
Frame = +2
Query: 50 LRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQAASRGAIVAEFN 229
LRP++V + E + +E A + D+ ++ GTS VYP A + ++A N
Sbjct: 150 LRPNVVLYDEGIASANIERAVQYLQQADLVVICGTSFRVYPFAGLIDYRNPKAQVLA-IN 208
Query: 230 IEP 238
EP
Sbjct: 209 AEP 211
>UniRef50_UPI00004992B3 Cluster: conserved hypothetical protein;
n=1; Entamoeba histolytica HM-1:IMSS|Rep: conserved
hypothetical protein - Entamoeba histolytica HM-1:IMSS
Length = 447
Score = 33.9 bits (74), Expect = 2.1
Identities = 13/32 (40%), Positives = 24/32 (75%)
Frame = -3
Query: 119 LHVQLLLKYHVLNFHRTTQCVVLARLHNEPFY 24
++V+LLL++++ +F TQ ++LA H+ PFY
Sbjct: 1 MNVKLLLQFYIASFVAHTQTLLLAMKHHRPFY 32
>UniRef50_A5AF92 Cluster: Putative uncharacterized protein; n=1;
Vitis vinifera|Rep: Putative uncharacterized protein -
Vitis vinifera (Grape)
Length = 343
Score = 33.9 bits (74), Expect = 2.1
Identities = 19/71 (26%), Positives = 32/71 (45%)
Frame = +2
Query: 23 CKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQAAS 202
C CGA LR ++ + ++L + AE DV L +GTS + PA ++
Sbjct: 201 CSNVDCGAKLRDTVLDWEDALPPKEMNPAEKHCRMADVVLCLGTSLQITPACNLPLKSLR 260
Query: 203 RGAIVAEFNIE 235
G + N++
Sbjct: 261 GGGKIVIVNLQ 271
>UniRef50_O96505 Cluster: SIR2; n=4; Sophophora|Rep: SIR2 -
Drosophila melanogaster (Fruit fly)
Length = 823
Score = 33.9 bits (74), Expect = 2.1
Identities = 15/44 (34%), Positives = 24/44 (54%)
Frame = +2
Query: 47 LLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAA 178
+++P IV+FGE L + CD+ +V+G+S V P A
Sbjct: 393 IMKPDIVFFGEGLPDEYHTVMATDKDVCDLLIVIGSSLKVRPVA 436
>UniRef50_A0C6J0 Cluster: Chromosome undetermined scaffold_152,
whole genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_152,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 449
Score = 33.9 bits (74), Expect = 2.1
Identities = 17/52 (32%), Positives = 29/52 (55%)
Frame = +2
Query: 23 CKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAA 178
C+K L++P +V+FGE L + + + + D+ +V+GTS V P A
Sbjct: 353 CEKCPKKGLVKPDVVFFGEGLPGEFF-YSWNCLKDADLLIVIGTSLKVMPFA 403
>UniRef50_Q6FKU1 Cluster: Similar to sp|P53686 Saccharomyces
cerevisiae YPL015c; n=3; Saccharomycetales|Rep: Similar
to sp|P53686 Saccharomyces cerevisiae YPL015c - Candida
glabrata (Yeast) (Torulopsis glabrata)
Length = 364
Score = 33.9 bits (74), Expect = 2.1
Identities = 19/63 (30%), Positives = 33/63 (52%), Gaps = 5/63 (7%)
Frame = +2
Query: 5 VKLLPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCD-----VCLVVGTSSVVY 169
+K + + C AL++P IV+FGE+L ++ + + + + +V GTS VY
Sbjct: 165 MKEFEYLRCPECEALIKPKIVFFGENLPKRFFDSWDTDLEWLEEESNSIVIVAGTSLTVY 224
Query: 170 PAA 178
P A
Sbjct: 225 PFA 227
>UniRef50_Q5AQ47 Cluster: Potential Sir2 family histone deacetylase;
n=2; Candida albicans|Rep: Potential Sir2 family histone
deacetylase - Candida albicans (Yeast)
Length = 657
Score = 33.9 bits (74), Expect = 2.1
Identities = 16/44 (36%), Positives = 25/44 (56%)
Frame = +2
Query: 47 LLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAA 178
+++P I +FGE L + A ++ D+ LV+GTS V P A
Sbjct: 495 VMKPDITFFGEQLPENFKIAINQDINKVDLVLVIGTSLKVAPVA 538
>UniRef50_A5DNV7 Cluster: Putative uncharacterized protein; n=1;
Pichia guilliermondii|Rep: Putative uncharacterized
protein - Pichia guilliermondii (Yeast) (Candida
guilliermondii)
Length = 403
Score = 33.9 bits (74), Expect = 2.1
Identities = 18/50 (36%), Positives = 23/50 (46%)
Frame = +2
Query: 47 LLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQA 196
L++P I +FGE L + CD+ LV GTS V P A A
Sbjct: 273 LIKPDITFFGEDLSSRFETMIGKDVEECDLLLVAGTSLKVEPVASIVRNA 322
>UniRef50_P06700 Cluster: NAD-dependent histone deacetylase SIR2;
n=13; Saccharomycetales|Rep: NAD-dependent histone
deacetylase SIR2 - Saccharomyces cerevisiae (Baker's
yeast)
Length = 562
Score = 33.9 bits (74), Expect = 2.1
Identities = 26/105 (24%), Positives = 43/105 (40%), Gaps = 9/105 (8%)
Frame = +2
Query: 47 LLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQAASRGAIV--- 217
+L+P I +FGE+L + ++ + CD+ + +GTS V P + S V
Sbjct: 437 VLKPDITFFGEALPNKFHKSIREDILECDLLICIGTSLKVAPVSEIVNMVPSHVPQVLIN 496
Query: 218 ------AEFNIEPTPATPDFHFYFEGPCGTTLPQALAD*LLRKKY 334
AEF++ D CG T+P + L K +
Sbjct: 497 RDPVKHAEFDLSLLGYCDDIAAMVAQKCGWTIPHKKWNDLKNKNF 541
>UniRef50_Q4V944 Cluster: Mdm4 protein; n=5; Clupeocephala|Rep: Mdm4
protein - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 496
Score = 33.5 bits (73), Expect = 2.8
Identities = 14/37 (37%), Positives = 17/37 (45%)
Frame = -1
Query: 310 SQCLWQCCTTRSFEVKMEIRCGRCWFYIKFCYNCTPR 200
+Q WQC R F ++ C RCW K Y PR
Sbjct: 305 TQDAWQCSECRKFNTPLQRYCMRCWALRKDWYKDCPR 341
>UniRef50_Q9I4E1 Cluster: NAD-dependent deacetylase 2; n=6;
Pseudomonadaceae|Rep: NAD-dependent deacetylase 2 -
Pseudomonas aeruginosa
Length = 256
Score = 33.5 bits (73), Expect = 2.8
Identities = 27/102 (26%), Positives = 41/102 (40%), Gaps = 1/102 (0%)
Frame = +2
Query: 8 KLLPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAM-STCDVCLVVGTSSVVYPAAMF 184
+L P C A CG +LRP +V F E L + ++ + D LVVGT++
Sbjct: 153 QLPPRC--AACGGVLRPPVVLFEEMLPEEAIDTLYRELRKGFDAVLVVGTTASFPYIVEP 210
Query: 185 APQAASRGAIVAEFNIEPTPATPDFHFYFEGPCGTTLPQALA 310
+ G AE N T + G +PQ ++
Sbjct: 211 VLRTRQAGGFTAEVNPGVTDLSERVDVKMTGRALDIMPQVVS 252
>UniRef50_Q5P3W1 Cluster: NAD-dependent deacetylase 2; n=4;
Proteobacteria|Rep: NAD-dependent deacetylase 2 -
Azoarcus sp. (strain EbN1) (Aromatoleum aromaticum
(strain EbN1))
Length = 260
Score = 33.1 bits (72), Expect = 3.7
Identities = 18/43 (41%), Positives = 24/43 (55%), Gaps = 1/43 (2%)
Frame = +2
Query: 38 CGALLRPHIVWFGESLEHDILEAAEHAMST-CDVCLVVGTSSV 163
CG +LRP IV FGE L L E + D+ + +GT+SV
Sbjct: 159 CGGVLRPDIVLFGEMLPETGLRRLEALLDDGVDLVVSIGTTSV 201
>UniRef50_A7SX90 Cluster: Predicted protein; n=3; Eumetazoa|Rep:
Predicted protein - Nematostella vectensis
Length = 306
Score = 33.1 bits (72), Expect = 3.7
Identities = 15/46 (32%), Positives = 27/46 (58%)
Frame = +2
Query: 44 ALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAM 181
++++P IV+FGESL + + D+ +V+G+S V P A+
Sbjct: 222 SIMKPDIVFFGESLPSNFYTHLGDDSNKADLLIVIGSSLKVRPVAL 267
>UniRef50_A7EMW8 Cluster: Putative uncharacterized protein; n=1;
Sclerotinia sclerotiorum 1980|Rep: Putative
uncharacterized protein - Sclerotinia sclerotiorum 1980
Length = 533
Score = 33.1 bits (72), Expect = 3.7
Identities = 22/87 (25%), Positives = 38/87 (43%), Gaps = 2/87 (2%)
Frame = +2
Query: 47 LLRPHIVWFGESLEHDILE-AAEHAMSTCDVCLVVGTSSVVYPAAMFAPQAASRGAIVAE 223
+++P I +FGESL + ++H D+ + +GTS V P + P S V +
Sbjct: 398 IMKPDITFFGESLPDKFADRLSKHDRDQVDLVITIGTSLKVAPVSEVVPYLPSN---VPQ 454
Query: 224 FNIEPTPAT-PDFHFYFEGPCGTTLPQ 301
I P + +F G C + +
Sbjct: 455 IQINRDPVSHVEFDIDLLGECDVVVSE 481
>UniRef50_A6SFT5 Cluster: Putative uncharacterized protein; n=1;
Botryotinia fuckeliana B05.10|Rep: Putative
uncharacterized protein - Botryotinia fuckeliana B05.10
Length = 224
Score = 33.1 bits (72), Expect = 3.7
Identities = 18/38 (47%), Positives = 25/38 (65%), Gaps = 3/38 (7%)
Frame = +2
Query: 50 LRPHIVWFGESLEHD--ILEAAEHAMSTCDV-CLVVGT 154
LRP+++ +GE D ILEAA+H + C V L+VGT
Sbjct: 130 LRPNVLLYGEPHPDDKEILEAAKHGLRICPVLVLIVGT 167
>UniRef50_Q81VZ1 Cluster: Bifunctional protein glmU [Includes:
UDP-N-acetylglucosamine pyrophosphorylase (EC 2.7.7.23)
(N-acetylglucosamine-1-phosphate uridyltransferase);
Glucosamine-1-phosphate N-acetyltransferase (EC
2.3.1.157)]; n=48; Bacteria|Rep: Bifunctional protein
glmU [Includes: UDP-N-acetylglucosamine
pyrophosphorylase (EC 2.7.7.23)
(N-acetylglucosamine-1-phosphate uridyltransferase);
Glucosamine-1-phosphate N-acetyltransferase (EC
2.3.1.157)] - Bacillus anthracis
Length = 459
Score = 33.1 bits (72), Expect = 3.7
Identities = 21/54 (38%), Positives = 31/54 (57%), Gaps = 2/54 (3%)
Frame = -2
Query: 300 CGSVVPQGPSK*KWKSGVA-GVGSILNSATIAPLEAACGANIAAGYT-TDDVPT 145
CGS+ K K+K+ + GV NS +AP+ GA +AAG T T++VP+
Sbjct: 380 CGSITVNYDGKNKFKTVIGNGVFIGCNSNLVAPVTVEDGAYVAAGSTITENVPS 433
>UniRef50_Q8X0B5 Cluster: Putative uncharacterized protein
B14D6.120; n=1; Neurospora crassa|Rep: Putative
uncharacterized protein B14D6.120 - Neurospora crassa
Length = 126
Score = 32.7 bits (71), Expect = 4.9
Identities = 24/81 (29%), Positives = 35/81 (43%), Gaps = 3/81 (3%)
Frame = +2
Query: 62 IVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYP--AAMFAPQAASRGAI-VAEFNI 232
I W G+ +L H M +C + G + P A++ Q SRGA + E+
Sbjct: 12 IGWLGDHFR-TLLTDQSHFMGSCSSVYIQG-KQLPGPSRASLTGRQRRSRGASDLDEYTS 69
Query: 233 EPTPATPDFHFYFEGPCGTTL 295
P PATP + G C T+
Sbjct: 70 PPNPATPGSRRFSNGHCAYTM 90
>UniRef50_Q874C2 Cluster: Cation-transporting ATPase; n=1; Trametes
versicolor|Rep: Cation-transporting ATPase - Trametes
versicolor (White-rot fungus) (Coriolus versicolor)
Length = 983
Score = 32.7 bits (71), Expect = 4.9
Identities = 12/38 (31%), Positives = 21/38 (55%)
Frame = +2
Query: 47 LLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSS 160
L P + W G+ + ++ +H +T DV + +GTSS
Sbjct: 253 LTTPALFWLGQKFYRNAYKSLKHGSATMDVLIAIGTSS 290
>UniRef50_A7TQE2 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 602
Score = 32.7 bits (71), Expect = 4.9
Identities = 14/44 (31%), Positives = 24/44 (54%)
Frame = +2
Query: 47 LLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAA 178
+++P I +FGE L + E + CD+ + +GTS V P +
Sbjct: 481 VMKPDITFFGEPLPDKFHNSIEKDVKGCDLLICIGTSLKVSPVS 524
>UniRef50_Q2P6K4 Cluster: Putative uncharacterized protein XOO1068;
n=8; Xanthomonadaceae|Rep: Putative uncharacterized
protein XOO1068 - Xanthomonas oryzae pv. oryzae (strain
MAFF 311018)
Length = 585
Score = 32.3 bits (70), Expect = 6.5
Identities = 15/36 (41%), Positives = 20/36 (55%)
Frame = +2
Query: 173 AAMFAPQAASRGAIVAEFNIEPTPATPDFHFYFEGP 280
AA +A +RGA A+F PTP+ PD + E P
Sbjct: 299 AAQLVVEATARGATQAQFPELPTPSVPDAQVFAEPP 334
>UniRef50_Q7RDB7 Cluster: Putative uncharacterized protein PY05506;
n=1; Plasmodium yoelii yoelii|Rep: Putative
uncharacterized protein PY05506 - Plasmodium yoelii
yoelii
Length = 33
Score = 32.3 bits (70), Expect = 6.5
Identities = 15/27 (55%), Positives = 20/27 (74%)
Frame = +1
Query: 337 MNYINIFYYFCLF*NIVLFPLQIYFKT 417
+N+INIF +F + NI FP+ IYFKT
Sbjct: 4 LNFINIFIFFQITNNI--FPIYIYFKT 28
>UniRef50_Q7PS76 Cluster: ENSANGP00000025231; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000025231 - Anopheles gambiae
str. PEST
Length = 182
Score = 32.3 bits (70), Expect = 6.5
Identities = 17/51 (33%), Positives = 28/51 (54%)
Frame = +2
Query: 14 LPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVV 166
+P C + CG L+P IV+FG+++ +E + D LV+G+S V
Sbjct: 134 IPPCPQ--CGGNLKPEIVFFGDNVPMPRIEKVVRMIIESDGVLVLGSSLTV 182
>UniRef50_A5DSX8 Cluster: NAD-dependent histone deacetylase SIR2;
n=1; Lodderomyces elongisporus NRRL YB-4239|Rep:
NAD-dependent histone deacetylase SIR2 - Lodderomyces
elongisporus (Yeast) (Saccharomyces elongisporus)
Length = 568
Score = 32.3 bits (70), Expect = 6.5
Identities = 15/42 (35%), Positives = 23/42 (54%)
Frame = +2
Query: 53 RPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAA 178
+P I +FGE+L + +S CD+ + +GTS V P A
Sbjct: 425 KPDITFFGEALPSRFHDLINTDISECDLLISIGTSLKVAPVA 466
>UniRef50_A5DJ74 Cluster: Putative uncharacterized protein; n=1;
Pichia guilliermondii|Rep: Putative uncharacterized
protein - Pichia guilliermondii (Yeast) (Candida
guilliermondii)
Length = 522
Score = 32.3 bits (70), Expect = 6.5
Identities = 15/44 (34%), Positives = 23/44 (52%)
Frame = +2
Query: 47 LLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAA 178
+++P I +FGE L + + CD+ + VGTS V P A
Sbjct: 375 VMKPDITFFGELLPAKFHDTINEDLHECDLVISVGTSLKVAPVA 418
>UniRef50_Q8N6T7 Cluster: Mono-ADP-ribosyltransferase sirtuin-6;
n=22; Euteleostomi|Rep: Mono-ADP-ribosyltransferase
sirtuin-6 - Homo sapiens (Human)
Length = 355
Score = 32.3 bits (70), Expect = 6.5
Identities = 19/68 (27%), Positives = 31/68 (45%)
Frame = +2
Query: 38 CGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQAASRGAIV 217
C LR I+ + +SL L A+ A D+ + +GTS + P+ RG +
Sbjct: 177 CRGELRDTILDWEDSLPDRDLALADEASRNADLSITLGTSLQIRPSGNLPLATKRRGGRL 236
Query: 218 AEFNIEPT 241
N++PT
Sbjct: 237 VIVNLQPT 244
>UniRef50_O59923 Cluster: NAD-dependent histone deacetylase SIR2;
n=3; Candida albicans|Rep: NAD-dependent histone
deacetylase SIR2 - Candida albicans (Yeast)
Length = 515
Score = 32.3 bits (70), Expect = 6.5
Identities = 18/48 (37%), Positives = 25/48 (52%)
Frame = +2
Query: 35 HCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAA 178
H GA+ +P I +FGE L + + D+ LV+GTS V P A
Sbjct: 389 HFGAI-KPTITFFGEDLPERFHTLMDKDLQQIDLFLVIGTSLKVEPVA 435
>UniRef50_Q8FUC8 Cluster: NAD-dependent deacetylase 1; n=6;
Corynebacterium|Rep: NAD-dependent deacetylase 1 -
Corynebacterium efficiens
Length = 281
Score = 32.3 bits (70), Expect = 6.5
Identities = 21/70 (30%), Positives = 30/70 (42%), Gaps = 1/70 (1%)
Frame = +2
Query: 32 AHCGA-LLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYPAAMFAPQAASRG 208
A CG+ LL+P +V+FGE + + D +V G+S V +A G
Sbjct: 184 ARCGSVLLKPDVVYFGEPVPSIRKTRVAQLLDGADAVVVAGSSLAVMSGYRIVIEAQRAG 243
Query: 209 AIVAEFNIEP 238
VA N P
Sbjct: 244 KPVAVINGGP 253
>UniRef50_A2F8N6 Cluster: Transcriptional regulator, Sir2 family
protein; n=1; Trichomonas vaginalis G3|Rep:
Transcriptional regulator, Sir2 family protein -
Trichomonas vaginalis G3
Length = 320
Score = 31.9 bits (69), Expect = 8.6
Identities = 14/53 (26%), Positives = 28/53 (52%)
Frame = +2
Query: 14 LPHCKKAHCGALLRPHIVWFGESLEHDILEAAEHAMSTCDVCLVVGTSSVVYP 172
+P C CG +++P ++ +G+ + D+ + + D+ V+GTS V P
Sbjct: 176 VPRCS---CGGVIQPDVMLYGDYNDDDLYTHLDKDVEQADLLFVLGTSLKVEP 225
>UniRef50_Q750H1 Cluster: AGL018Cp; n=1; Eremothecium gossypii|Rep:
AGL018Cp - Ashbya gossypii (Yeast) (Eremothecium
gossypii)
Length = 340
Score = 31.9 bits (69), Expect = 8.6
Identities = 19/53 (35%), Positives = 27/53 (50%), Gaps = 6/53 (11%)
Frame = +2
Query: 38 CGALLRPHIVWFGESLEHDILEAAEHAMSTCD------VCLVVGTSSVVYPAA 178
C L++P IV+FGE L + + +S + +V GTS VVYP A
Sbjct: 167 CEGLIKPRIVFFGEDLPSVFYTSWDKLLSEMQAGKEDYLVIVAGTSLVVYPFA 219
>UniRef50_A3GG83 Cluster: DASH complex subunit ask1; n=2; Pichia
stipitis|Rep: DASH complex subunit ask1 - Pichia
stipitis (Yeast)
Length = 540
Score = 31.9 bits (69), Expect = 8.6
Identities = 23/72 (31%), Positives = 33/72 (45%), Gaps = 1/72 (1%)
Frame = +2
Query: 83 LEHDILEAAEHAM-STCDVCLVVGTSSVVYPAAMFAPQAASRGAIVAEFNIEPTPATPDF 259
+ H+ ++A+ A S+ DV V SV PA A +GA AE I+ P+TP F
Sbjct: 279 VSHNSKDSAQSAAASSRDVLSPVLIESVYSPAKSIHSSAHRKGAASAENTIQRFPSTPKF 338
Query: 260 HFYFEGPCGTTL 295
G G +
Sbjct: 339 VERLSGGAGVDI 350
>UniRef50_A0B7T8 Cluster: Tungsten formylmethanofuran dehydrogenase
subunit B; n=1; Methanosaeta thermophila PT|Rep:
Tungsten formylmethanofuran dehydrogenase subunit B -
Methanosaeta thermophila (strain DSM 6194 / PT)
(Methanothrixthermophila (strain DSM 6194 / PT))
Length = 406
Score = 31.9 bits (69), Expect = 8.6
Identities = 12/33 (36%), Positives = 21/33 (63%)
Frame = +2
Query: 65 VWFGESLEHDILEAAEHAMSTCDVCLVVGTSSV 163
V FG+ ++H + + A+ +CD+ LVVGT +
Sbjct: 295 VSFGDGVDHGPMYSVVEALKSCDLALVVGTDPI 327
>UniRef50_Q9NRC8 Cluster: NAD-dependent deacetylase sirtuin-7; n=24;
Eumetazoa|Rep: NAD-dependent deacetylase sirtuin-7 -
Homo sapiens (Human)
Length = 400
Score = 31.9 bits (69), Expect = 8.6
Identities = 30/98 (30%), Positives = 41/98 (41%), Gaps = 6/98 (6%)
Frame = +2
Query: 38 CGALLRPHIVWFGE--SLEHDI-LEAAEHAMSTCDVCLVVGTSSVV---YPAAMFAPQAA 199
CG LR IV FGE +L + EAA A S D L +G+S V YP +
Sbjct: 228 CGTQLRDTIVHFGERGTLGQPLNWEAATEAASRADTILCLGSSLKVLKKYPRLWCMTKPP 287
Query: 200 SRGAIVAEFNIEPTPATPDFHFYFEGPCGTTLPQALAD 313
SR + N++ TP G C + +A+
Sbjct: 288 SRRPKLYIVNLQWTPKDDWAALKLHGKCDDVMRLLMAE 325
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 454,854,954
Number of Sequences: 1657284
Number of extensions: 8632452
Number of successful extensions: 22592
Number of sequences better than 10.0: 210
Number of HSP's better than 10.0 without gapping: 21831
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 22541
length of database: 575,637,011
effective HSP length: 95
effective length of database: 418,195,031
effective search space used: 30528237263
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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