Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= bmnc28g04
(610 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
CR456743-1|CAG33024.1| 538|Homo sapiens KPNA1 protein. 194 2e-49
BT006959-1|AAP35605.1| 538|Homo sapiens karyopherin alpha 1 (im... 194 2e-49
BC090864-1|AAH90864.1| 538|Homo sapiens karyopherin alpha 1 (im... 194 2e-49
BC003009-1|AAH03009.1| 538|Homo sapiens karyopherin alpha 1 (im... 194 2e-49
BC002374-1|AAH02374.1| 538|Homo sapiens karyopherin alpha 1 (im... 194 2e-49
BC047409-1|AAH47409.1| 539|Homo sapiens karyopherin alpha 5 (im... 194 3e-49
AL132795-5|CAI20500.1| 539|Homo sapiens karyopherin alpha 5 (im... 194 3e-49
AF005361-1|AAC51868.1| 536|Homo sapiens importin alpha 6 protein. 193 4e-49
S75295-1|AAC60648.1| 538|Homo sapiens nucleoprotein interactor ... 189 8e-48
BT009843-1|AAP88845.1| 536|Homo sapiens karyopherin alpha 6 (im... 187 3e-47
BC020520-1|AAH20520.1| 536|Homo sapiens karyopherin alpha 6 (im... 187 3e-47
AL445248-5|CAH71948.1| 536|Homo sapiens karyopherin alpha 6 (im... 187 3e-47
AL049795-3|CAI22056.1| 536|Homo sapiens karyopherin alpha 6 (im... 187 3e-47
AF060543-1|AAC15233.1| 536|Homo sapiens importin alpha 7 subuni... 187 3e-47
BT006665-1|AAP35311.1| 529|Homo sapiens karyopherin alpha 2 (RA... 159 9e-39
BC005978-1|AAH05978.1| 529|Homo sapiens karyopherin alpha 2 (RA... 159 9e-39
U28386-1|AAA69957.1| 529|Homo sapiens hSRP1alpha protein. 157 3e-38
U09559-1|AAA65700.1| 529|Homo sapiens Rch1 protein. 157 3e-38
BC053343-1|AAH53343.1| 529|Homo sapiens karyopherin alpha 2 (RA... 157 3e-38
AJ303086-1|CAC83080.1| 529|Homo sapiens karyopherin alpha 2 pro... 157 3e-38
BC067848-1|AAH67848.1| 529|Homo sapiens karyopherin alpha 2 (RA... 155 9e-38
D89618-1|BAA20378.1| 521|Homo sapiens karyopherin alhph 3 protein. 145 1e-34
BC024202-1|AAH24202.1| 521|Homo sapiens karyopherin alpha 3 (im... 144 2e-34
BC017355-1|AAH17355.1| 521|Homo sapiens karyopherin alpha 3 (im... 144 2e-34
AL136301-1|CAH71145.1| 521|Homo sapiens karyopherin alpha 3 (im... 144 2e-34
AL135901-3|CAI40716.1| 521|Homo sapiens karyopherin alpha 3 (im... 144 2e-34
AK223480-1|BAD97200.1| 521|Homo sapiens karyopherin alpha 3 var... 144 2e-34
AF005263-1|AAQ13404.1| 521|Homo sapiens importin alpha-3 subuni... 144 2e-34
Y12394-1|CAA73026.1| 521|Homo sapiens SRP1-like protein protein. 143 4e-34
BC035090-1|AAH35090.1| 521|Homo sapiens karyopherin alpha 3 (im... 143 4e-34
AF034756-1|AAB87693.1| 521|Homo sapiens importin-alpha homolog ... 142 1e-33
U93240-1|AAC25605.1| 521|Homo sapiens importin alpha 3 protein. 138 1e-32
BC034493-1|AAH34493.1| 521|Homo sapiens karyopherin alpha 4 (im... 138 1e-32
BC028691-1|AAH28691.1| 521|Homo sapiens karyopherin alpha 4 (im... 138 1e-32
AB002533-1|BAA19546.1| 521|Homo sapiens Qip1 protein. 138 1e-32
AL132795-6|CAI20501.1| 142|Homo sapiens karyopherin alpha 5 (im... 135 1e-31
AL049795-1|CAI22054.1| 321|Homo sapiens karyopherin alpha 6 (im... 93 7e-19
Y12393-1|CAA73025.1| 281|Homo sapiens SRP1-like protein protein. 41 0.003
CR533552-1|CAG38583.1| 509|Homo sapiens SPAG6 protein. 36 0.11
BC030585-1|AAH30585.1| 458|Homo sapiens sperm associated antige... 36 0.11
AL513128-4|CAH72210.1| 509|Homo sapiens sperm associated antige... 36 0.11
AL513128-3|CAH72209.1| 458|Homo sapiens sperm associated antige... 36 0.11
AL513128-1|CAH72207.1| 246|Homo sapiens sperm associated antige... 36 0.11
AL158211-15|CAI15963.1| 509|Homo sapiens sperm associated antig... 36 0.11
AL158211-14|CAI15962.1| 458|Homo sapiens sperm associated antig... 36 0.11
AL158211-12|CAI15960.1| 246|Homo sapiens sperm associated antig... 36 0.11
AK223275-1|BAD96995.1| 1181|Homo sapiens AT rich interactive dom... 36 0.11
AF079363-1|AAC32590.1| 509|Homo sapiens sperm flagellar protein... 36 0.11
BC041699-1|AAH41699.1| 659|Homo sapiens armadillo repeat contai... 35 0.26
BC032661-1|AAH32661.1| 659|Homo sapiens armadillo repeat contai... 35 0.26
AK001882-1|BAA91959.1| 431|Homo sapiens protein ( Homo sapiens ... 35 0.26
AL096748-1|CAB46423.1| 242|Homo sapiens hypothetical protein pr... 34 0.34
BC112895-1|AAI12896.1| 164|Homo sapiens ARID1A protein protein. 34 0.45
AL512408-3|CAI23484.1| 2285|Homo sapiens AT rich interactive dom... 34 0.45
AL512408-1|CAI23482.1| 1685|Homo sapiens AT rich interactive dom... 34 0.45
AL034380-9|CAI21623.1| 2285|Homo sapiens AT rich interactive dom... 34 0.45
AL034380-6|CAI21621.1| 1685|Homo sapiens AT rich interactive dom... 34 0.45
AK074940-1|BAC11306.1| 754|Homo sapiens protein ( Homo sapiens ... 34 0.45
AK027655-1|BAB55270.1| 613|Homo sapiens protein ( Homo sapiens ... 34 0.45
AK027467-1|BAB55132.1| 375|Homo sapiens protein ( Homo sapiens ... 34 0.45
AK027442-1|BAB55114.1| 527|Homo sapiens protein ( Homo sapiens ... 34 0.45
AF521670-1|AAN03446.1| 1999|Homo sapiens SWI/SNF chromatin remod... 34 0.45
AF265208-1|AAF75765.1| 1927|Homo sapiens SWI-SNF complex protein... 34 0.45
AF231056-1|AAG33967.1| 2285|Homo sapiens BRG1-Associated Factor ... 34 0.45
AF219114-1|AAG17549.2| 1939|Homo sapiens chromatin remodelling f... 34 0.45
AF268913-1|AAK54505.1| 1685|Homo sapiens OSA1 nuclear protein pr... 32 1.4
L09190-1|AAA65582.1| 1898|Homo sapiens trichohyalin protein. 31 3.2
AL589986-1|CAH70024.1| 1943|Homo sapiens trichohyalin protein. 31 3.2
AM156947-1|CAJ42307.1| 1221|Homo sapiens centrosome and spindle ... 31 4.2
AJ583433-1|CAE47426.1| 876|Homo sapiens centrosome spindle pole... 31 4.2
BC131591-1|AAI31592.1| 890|Homo sapiens PACS2 protein protein. 29 9.7
BC065220-1|AAH65220.2| 889|Homo sapiens phosphofurin acidic clu... 29 9.7
AY320284-1|AAQ83882.2| 889|Homo sapiens PACS2 protein. 29 9.7
AB011174-1|BAA25528.1| 962|Homo sapiens KIAA0602 protein protein. 29 9.7
>CR456743-1|CAG33024.1| 538|Homo sapiens KPNA1 protein.
Length = 538
Score = 194 bits (473), Expect = 2e-49
Identities = 103/180 (57%), Positives = 127/180 (70%), Gaps = 10/180 (5%)
Frame = +1
Query: 100 YKNVGLSADELRRRREEEGVQLRKQKREQQLFKRRNVNLPGTNAA------GAASQEDIN 261
YKN L+ DE+RRRREEEG+QLRKQKRE+QLFKRRNV G + IN
Sbjct: 14 YKNKSLNPDEMRRRREEEGLQLRKQKREEQLFKRRNVATAEEETEEEVMSDGGFHEAQIN 73
Query: 262 ---ISPSDCITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQS-GIVPKFIE 429
++P IT DM+ ++ +PE+Q+ ATQKFRKLLSKEPNPPID VI + G+V +F+E
Sbjct: 74 NMEMAPGGVITSDMIEMIFSKSPEQQLSATQKFRKLLSKEPNPPIDEVISTPGVVARFVE 133
Query: 430 FLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWAL 609
FL +N TLQFE+AW LTNIASG+S QTRIV+ GAV + + LLS E+V EQAVWAL
Sbjct: 134 FLKRKENCTLQFESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFEDVQEQAVWAL 193
Score = 51.2 bits (117), Expect = 3e-06
Identities = 43/146 (29%), Positives = 72/146 (49%), Gaps = 5/146 (3%)
Frame = +1
Query: 187 QLFKRRNVNLPGTNAAGAASQEDINISPSD---CITPDM-VLAVYLDNPEEQVIATQKFR 354
QLF ++N NA A S SP ++P + VL+ L + V+A +
Sbjct: 218 QLFSKQNRLTMTRNAVWALSNLCRGKSPPPEFAKVSPCLNVLSWLLFVSDTDVLADACWA 277
Query: 355 -KLLSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVD 531
LS PN I AVI +G+ + +E L H + + A A+ NI +G QT+++++
Sbjct: 278 LSYLSDGPNDKIQAVIDAGVCRRLVELLM-HNDYKVVSPALRAVGNIVTGDDIQTQVILN 336
Query: 532 YGAVNVLVGLLSGSTENVCEQAVWAL 609
A+ L+ LLS E++ ++A W +
Sbjct: 337 CSALQSLLHLLSSPKESIKKEACWTI 362
Score = 43.2 bits (97), Expect = 7e-04
Identities = 29/73 (39%), Positives = 39/73 (53%), Gaps = 1/73 (1%)
Frame = +1
Query: 394 VIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGS 573
VIQ+G VP FIE L++ +Q +A WAL NIA S+ V+D + L+ L S
Sbjct: 165 VIQAGAVPIFIELLSSEFED-VQEQAVWALGNIAGDSTMCRDYVLDCNILPPLLQLFSKQ 223
Query: 574 TE-NVCEQAVWAL 609
+ AVWAL
Sbjct: 224 NRLTMTRNAVWAL 236
Score = 41.9 bits (94), Expect = 0.002
Identities = 23/74 (31%), Positives = 33/74 (44%)
Frame = +1
Query: 388 DAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLS 567
D V+ I+P ++ + T+ A WAL+N+ G S +NVL LL
Sbjct: 205 DYVLDCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKSPPPEFAKVSPCLNVLSWLLF 264
Query: 568 GSTENVCEQAVWAL 609
S +V A WAL
Sbjct: 265 VSDTDVLADACWAL 278
Score = 40.3 bits (90), Expect = 0.005
Identities = 25/73 (34%), Positives = 37/73 (50%), Gaps = 1/73 (1%)
Frame = +1
Query: 385 IDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSG-QTRIVVDYGAVNVLVGL 561
I VI + I P I L + T + EAAWA+TN SG S Q + +V+ G + L L
Sbjct: 373 IQTVIDANIFPALISILQTAEFRTRK-EAAWAITNATSGGSAEQIKYLVELGCIKPLCDL 431
Query: 562 LSGSTENVCEQAV 600
L+ + + A+
Sbjct: 432 LTVMDSKIVQVAL 444
Score = 37.9 bits (84), Expect = 0.028
Identities = 16/72 (22%), Positives = 37/72 (51%)
Frame = +1
Query: 394 VIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGS 573
++ + + L++ K +++ EA W ++NI +G+ Q + V+D L+ +L +
Sbjct: 334 ILNCSALQSLLHLLSSPKE-SIKKEACWTISNITAGNRAQIQTVIDANIFPALISILQTA 392
Query: 574 TENVCEQAVWAL 609
++A WA+
Sbjct: 393 EFRTRKEAAWAI 404
>BT006959-1|AAP35605.1| 538|Homo sapiens karyopherin alpha 1
(importin alpha 5) protein.
Length = 538
Score = 194 bits (473), Expect = 2e-49
Identities = 103/180 (57%), Positives = 127/180 (70%), Gaps = 10/180 (5%)
Frame = +1
Query: 100 YKNVGLSADELRRRREEEGVQLRKQKREQQLFKRRNVNLPGTNAA------GAASQEDIN 261
YKN L+ DE+RRRREEEG+QLRKQKRE+QLFKRRNV G + IN
Sbjct: 14 YKNKSLNPDEMRRRREEEGLQLRKQKREEQLFKRRNVATAEEETEEEVMSDGGFHEAQIN 73
Query: 262 ---ISPSDCITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQS-GIVPKFIE 429
++P IT DM+ ++ +PE+Q+ ATQKFRKLLSKEPNPPID VI + G+V +F+E
Sbjct: 74 NMEMAPGGVITSDMIEMIFSKSPEQQLSATQKFRKLLSKEPNPPIDEVISTPGVVARFVE 133
Query: 430 FLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWAL 609
FL +N TLQFE+AW LTNIASG+S QTRIV+ GAV + + LLS E+V EQAVWAL
Sbjct: 134 FLKRKENCTLQFESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFEDVQEQAVWAL 193
Score = 51.2 bits (117), Expect = 3e-06
Identities = 43/146 (29%), Positives = 72/146 (49%), Gaps = 5/146 (3%)
Frame = +1
Query: 187 QLFKRRNVNLPGTNAAGAASQEDINISPSD---CITPDM-VLAVYLDNPEEQVIATQKFR 354
QLF ++N NA A S SP ++P + VL+ L + V+A +
Sbjct: 218 QLFSKQNRLTMTRNAVWALSNLCRGKSPPPEFAKVSPCLNVLSWLLFVSDTDVLADACWA 277
Query: 355 -KLLSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVD 531
LS PN I AVI +G+ + +E L H + + A A+ NI +G QT+++++
Sbjct: 278 LSYLSDGPNDKIQAVIDAGVCRRLVELLM-HNDYKVVSPALRAVGNIVTGDDIQTQVILN 336
Query: 532 YGAVNVLVGLLSGSTENVCEQAVWAL 609
A+ L+ LLS E++ ++A W +
Sbjct: 337 CSALQSLLHLLSSPKESIKKEACWTI 362
Score = 43.2 bits (97), Expect = 7e-04
Identities = 29/73 (39%), Positives = 39/73 (53%), Gaps = 1/73 (1%)
Frame = +1
Query: 394 VIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGS 573
VIQ+G VP FIE L++ +Q +A WAL NIA S+ V+D + L+ L S
Sbjct: 165 VIQAGAVPIFIELLSSEFED-VQEQAVWALGNIAGDSTMCRDYVLDCNILPPLLQLFSKQ 223
Query: 574 TE-NVCEQAVWAL 609
+ AVWAL
Sbjct: 224 NRLTMTRNAVWAL 236
Score = 41.9 bits (94), Expect = 0.002
Identities = 23/74 (31%), Positives = 33/74 (44%)
Frame = +1
Query: 388 DAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLS 567
D V+ I+P ++ + T+ A WAL+N+ G S +NVL LL
Sbjct: 205 DYVLDCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKSPPPEFAKVSPCLNVLSWLLF 264
Query: 568 GSTENVCEQAVWAL 609
S +V A WAL
Sbjct: 265 VSDTDVLADACWAL 278
Score = 40.3 bits (90), Expect = 0.005
Identities = 25/73 (34%), Positives = 37/73 (50%), Gaps = 1/73 (1%)
Frame = +1
Query: 385 IDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSG-QTRIVVDYGAVNVLVGL 561
I VI + I P I L + T + EAAWA+TN SG S Q + +V+ G + L L
Sbjct: 373 IQTVIDANIFPALISILQTAEFRTRK-EAAWAITNATSGGSAEQIKYLVELGCIKPLCDL 431
Query: 562 LSGSTENVCEQAV 600
L+ + + A+
Sbjct: 432 LTVMDSKIVQVAL 444
Score = 37.9 bits (84), Expect = 0.028
Identities = 16/72 (22%), Positives = 37/72 (51%)
Frame = +1
Query: 394 VIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGS 573
++ + + L++ K +++ EA W ++NI +G+ Q + V+D L+ +L +
Sbjct: 334 ILNCSALQSLLHLLSSPKE-SIKKEACWTISNITAGNRAQIQTVIDANIFPALISILQTA 392
Query: 574 TENVCEQAVWAL 609
++A WA+
Sbjct: 393 EFRTRKEAAWAI 404
>BC090864-1|AAH90864.1| 538|Homo sapiens karyopherin alpha 1
(importin alpha 5) protein.
Length = 538
Score = 194 bits (473), Expect = 2e-49
Identities = 103/180 (57%), Positives = 127/180 (70%), Gaps = 10/180 (5%)
Frame = +1
Query: 100 YKNVGLSADELRRRREEEGVQLRKQKREQQLFKRRNVNLPGTNAA------GAASQEDIN 261
YKN L+ DE+RRRREEEG+QLRKQKRE+QLFKRRNV G + IN
Sbjct: 14 YKNKSLNPDEMRRRREEEGLQLRKQKREEQLFKRRNVATAEEETEEEVMSDGGFHEAQIN 73
Query: 262 ---ISPSDCITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQS-GIVPKFIE 429
++P IT DM+ ++ +PE+Q+ ATQKFRKLLSKEPNPPID VI + G+V +F+E
Sbjct: 74 NMEMAPGGVITSDMIEMIFSKSPEQQLSATQKFRKLLSKEPNPPIDEVISTPGVVARFVE 133
Query: 430 FLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWAL 609
FL +N TLQFE+AW LTNIASG+S QTRIV+ GAV + + LLS E+V EQAVWAL
Sbjct: 134 FLKRKENCTLQFESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFEDVQEQAVWAL 193
Score = 51.2 bits (117), Expect = 3e-06
Identities = 43/146 (29%), Positives = 72/146 (49%), Gaps = 5/146 (3%)
Frame = +1
Query: 187 QLFKRRNVNLPGTNAAGAASQEDINISPSD---CITPDM-VLAVYLDNPEEQVIATQKFR 354
QLF ++N NA A S SP ++P + VL+ L + V+A +
Sbjct: 218 QLFSKQNRLTMTRNAVWALSNLCRGKSPPPEFAKVSPCLNVLSWLLFVSDTDVLADACWA 277
Query: 355 -KLLSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVD 531
LS PN I AVI +G+ + +E L H + + A A+ NI +G QT+++++
Sbjct: 278 LSYLSDGPNDKIQAVIDAGVCRRLVELLM-HNDYKVVSPALRAVGNIVTGDDIQTQVILN 336
Query: 532 YGAVNVLVGLLSGSTENVCEQAVWAL 609
A+ L+ LLS E++ ++A W +
Sbjct: 337 CSALQSLLHLLSSPKESIKKEACWTI 362
Score = 44.0 bits (99), Expect = 4e-04
Identities = 29/73 (39%), Positives = 39/73 (53%), Gaps = 1/73 (1%)
Frame = +1
Query: 394 VIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGS 573
VIQ+G VP FIE L++ +Q +A WAL NIA S+ V+D + L+ L S
Sbjct: 165 VIQAGAVPIFIELLSSEFED-VQEQAVWALGNIAGDSTMYRDYVLDCNILPPLLQLFSKQ 223
Query: 574 TE-NVCEQAVWAL 609
+ AVWAL
Sbjct: 224 NRLTMTRNAVWAL 236
Score = 41.9 bits (94), Expect = 0.002
Identities = 23/74 (31%), Positives = 33/74 (44%)
Frame = +1
Query: 388 DAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLS 567
D V+ I+P ++ + T+ A WAL+N+ G S +NVL LL
Sbjct: 205 DYVLDCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKSPPPEFAKVSPCLNVLSWLLF 264
Query: 568 GSTENVCEQAVWAL 609
S +V A WAL
Sbjct: 265 VSDTDVLADACWAL 278
Score = 40.3 bits (90), Expect = 0.005
Identities = 25/73 (34%), Positives = 37/73 (50%), Gaps = 1/73 (1%)
Frame = +1
Query: 385 IDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSG-QTRIVVDYGAVNVLVGL 561
I VI + I P I L + T + EAAWA+TN SG S Q + +V+ G + L L
Sbjct: 373 IQTVIDANIFPALISILQTAEFRTRK-EAAWAITNATSGGSAEQIKYLVELGCIKPLCDL 431
Query: 562 LSGSTENVCEQAV 600
L+ + + A+
Sbjct: 432 LTVMDSKIVQVAL 444
Score = 37.9 bits (84), Expect = 0.028
Identities = 16/72 (22%), Positives = 37/72 (51%)
Frame = +1
Query: 394 VIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGS 573
++ + + L++ K +++ EA W ++NI +G+ Q + V+D L+ +L +
Sbjct: 334 ILNCSALQSLLHLLSSPKE-SIKKEACWTISNITAGNRAQIQTVIDANIFPALISILQTA 392
Query: 574 TENVCEQAVWAL 609
++A WA+
Sbjct: 393 EFRTRKEAAWAI 404
>BC003009-1|AAH03009.1| 538|Homo sapiens karyopherin alpha 1
(importin alpha 5) protein.
Length = 538
Score = 194 bits (473), Expect = 2e-49
Identities = 103/180 (57%), Positives = 127/180 (70%), Gaps = 10/180 (5%)
Frame = +1
Query: 100 YKNVGLSADELRRRREEEGVQLRKQKREQQLFKRRNVNLPGTNAA------GAASQEDIN 261
YKN L+ DE+RRRREEEG+QLRKQKRE+QLFKRRNV G + IN
Sbjct: 14 YKNKSLNPDEMRRRREEEGLQLRKQKREEQLFKRRNVATAEEETEEEVMSDGGFHEAQIN 73
Query: 262 ---ISPSDCITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQS-GIVPKFIE 429
++P IT DM+ ++ +PE+Q+ ATQKFRKLLSKEPNPPID VI + G+V +F+E
Sbjct: 74 NMEMAPGGVITSDMIEMIFSKSPEQQLSATQKFRKLLSKEPNPPIDEVISTPGVVARFVE 133
Query: 430 FLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWAL 609
FL +N TLQFE+AW LTNIASG+S QTRIV+ GAV + + LLS E+V EQAVWAL
Sbjct: 134 FLKRKENCTLQFESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFEDVQEQAVWAL 193
Score = 51.2 bits (117), Expect = 3e-06
Identities = 43/146 (29%), Positives = 72/146 (49%), Gaps = 5/146 (3%)
Frame = +1
Query: 187 QLFKRRNVNLPGTNAAGAASQEDINISPSD---CITPDM-VLAVYLDNPEEQVIATQKFR 354
QLF ++N NA A S SP ++P + VL+ L + V+A +
Sbjct: 218 QLFSKQNRLTMTRNAVWALSNLCRGKSPPPEFAKVSPCLNVLSWLLFVSDTDVLADACWA 277
Query: 355 -KLLSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVD 531
LS PN I AVI +G+ + +E L H + + A A+ NI +G QT+++++
Sbjct: 278 LSYLSDGPNDKIQAVIDAGVCRRLVELLM-HNDYKVVSPALRAVGNIVTGDDIQTQVILN 336
Query: 532 YGAVNVLVGLLSGSTENVCEQAVWAL 609
A+ L+ LLS E++ ++A W +
Sbjct: 337 CSALQSLLHLLSSPKESIKKEACWTI 362
Score = 43.2 bits (97), Expect = 7e-04
Identities = 29/73 (39%), Positives = 39/73 (53%), Gaps = 1/73 (1%)
Frame = +1
Query: 394 VIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGS 573
VIQ+G VP FIE L++ +Q +A WAL NIA S+ V+D + L+ L S
Sbjct: 165 VIQAGAVPIFIELLSSEFED-VQEQAVWALGNIAGDSTMCRDYVLDCNILPPLLQLFSKQ 223
Query: 574 TE-NVCEQAVWAL 609
+ AVWAL
Sbjct: 224 NRLTMTRNAVWAL 236
Score = 41.9 bits (94), Expect = 0.002
Identities = 23/74 (31%), Positives = 33/74 (44%)
Frame = +1
Query: 388 DAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLS 567
D V+ I+P ++ + T+ A WAL+N+ G S +NVL LL
Sbjct: 205 DYVLDCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKSPPPEFAKVSPCLNVLSWLLF 264
Query: 568 GSTENVCEQAVWAL 609
S +V A WAL
Sbjct: 265 VSDTDVLADACWAL 278
Score = 40.3 bits (90), Expect = 0.005
Identities = 25/73 (34%), Positives = 37/73 (50%), Gaps = 1/73 (1%)
Frame = +1
Query: 385 IDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSG-QTRIVVDYGAVNVLVGL 561
I VI + I P I L + T + EAAWA+TN SG S Q + +V+ G + L L
Sbjct: 373 IQTVIDANIFPALISILQTAEFRTRK-EAAWAITNATSGGSAEQIKYLVELGCIKPLCDL 431
Query: 562 LSGSTENVCEQAV 600
L+ + + A+
Sbjct: 432 LTVMDSKIVQVAL 444
Score = 37.9 bits (84), Expect = 0.028
Identities = 16/72 (22%), Positives = 37/72 (51%)
Frame = +1
Query: 394 VIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGS 573
++ + + L++ K +++ EA W ++NI +G+ Q + V+D L+ +L +
Sbjct: 334 ILNCSALQSLLHLLSSPKE-SIKKEACWTISNITAGNRAQIQTVIDANIFPALISILQTA 392
Query: 574 TENVCEQAVWAL 609
++A WA+
Sbjct: 393 EFRTRKEAAWAI 404
>BC002374-1|AAH02374.1| 538|Homo sapiens karyopherin alpha 1
(importin alpha 5) protein.
Length = 538
Score = 194 bits (473), Expect = 2e-49
Identities = 103/180 (57%), Positives = 127/180 (70%), Gaps = 10/180 (5%)
Frame = +1
Query: 100 YKNVGLSADELRRRREEEGVQLRKQKREQQLFKRRNVNLPGTNAA------GAASQEDIN 261
YKN L+ DE+RRRREEEG+QLRKQKRE+QLFKRRNV G + IN
Sbjct: 14 YKNKSLNPDEMRRRREEEGLQLRKQKREEQLFKRRNVATAEEETEEEVMSDGGFHEAQIN 73
Query: 262 ---ISPSDCITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQS-GIVPKFIE 429
++P IT DM+ ++ +PE+Q+ ATQKFRKLLSKEPNPPID VI + G+V +F+E
Sbjct: 74 NMEMAPGGVITSDMIEMIFSKSPEQQLSATQKFRKLLSKEPNPPIDEVISTPGVVARFVE 133
Query: 430 FLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWAL 609
FL +N TLQFE+AW LTNIASG+S QTRIV+ GAV + + LLS E+V EQAVWAL
Sbjct: 134 FLKRKENCTLQFESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFEDVQEQAVWAL 193
Score = 51.2 bits (117), Expect = 3e-06
Identities = 43/146 (29%), Positives = 72/146 (49%), Gaps = 5/146 (3%)
Frame = +1
Query: 187 QLFKRRNVNLPGTNAAGAASQEDINISPSD---CITPDM-VLAVYLDNPEEQVIATQKFR 354
QLF ++N NA A S SP ++P + VL+ L + V+A +
Sbjct: 218 QLFSKQNRLTMTRNAVWALSNLCRGKSPPPEFAKVSPCLNVLSWLLFVSDTDVLADACWA 277
Query: 355 -KLLSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVD 531
LS PN I AVI +G+ + +E L H + + A A+ NI +G QT+++++
Sbjct: 278 LSYLSDGPNDKIQAVIDAGVCRRLVELLM-HNDYKVVSPALRAVGNIVTGDDIQTQVILN 336
Query: 532 YGAVNVLVGLLSGSTENVCEQAVWAL 609
A+ L+ LLS E++ ++A W +
Sbjct: 337 CSALQSLLHLLSSPKESIKKEACWTI 362
Score = 43.2 bits (97), Expect = 7e-04
Identities = 29/73 (39%), Positives = 39/73 (53%), Gaps = 1/73 (1%)
Frame = +1
Query: 394 VIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGS 573
VIQ+G VP FIE L++ +Q +A WAL NIA S+ V+D + L+ L S
Sbjct: 165 VIQAGAVPIFIELLSSEFED-VQEQAVWALGNIAGDSTMCRDYVLDCNILPPLLQLFSKQ 223
Query: 574 TE-NVCEQAVWAL 609
+ AVWAL
Sbjct: 224 NRLTMTRNAVWAL 236
Score = 41.9 bits (94), Expect = 0.002
Identities = 23/74 (31%), Positives = 33/74 (44%)
Frame = +1
Query: 388 DAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLS 567
D V+ I+P ++ + T+ A WAL+N+ G S +NVL LL
Sbjct: 205 DYVLDCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKSPPPEFAKVSPCLNVLSWLLF 264
Query: 568 GSTENVCEQAVWAL 609
S +V A WAL
Sbjct: 265 VSDTDVLADACWAL 278
Score = 40.3 bits (90), Expect = 0.005
Identities = 25/73 (34%), Positives = 37/73 (50%), Gaps = 1/73 (1%)
Frame = +1
Query: 385 IDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSG-QTRIVVDYGAVNVLVGL 561
I VI + I P I L + T + EAAWA+TN SG S Q + +V+ G + L L
Sbjct: 373 IQTVIDANIFPALISILQTAEFRTRK-EAAWAITNATSGGSAEQIKYLVELGCIKPLCDL 431
Query: 562 LSGSTENVCEQAV 600
L+ + + A+
Sbjct: 432 LTVMDSKIVQVAL 444
Score = 37.9 bits (84), Expect = 0.028
Identities = 16/72 (22%), Positives = 37/72 (51%)
Frame = +1
Query: 394 VIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGS 573
++ + + L++ K +++ EA W ++NI +G+ Q + V+D L+ +L +
Sbjct: 334 ILNCSALQSLLHLLSSPKE-SIKKEACWTISNITAGNRAQIQTVIDANIFPALISILQTA 392
Query: 574 TENVCEQAVWAL 609
++A WA+
Sbjct: 393 EFRTRKEAAWAI 404
>BC047409-1|AAH47409.1| 539|Homo sapiens karyopherin alpha 5
(importin alpha 6) protein.
Length = 539
Score = 194 bits (472), Expect = 3e-49
Identities = 100/178 (56%), Positives = 132/178 (74%), Gaps = 8/178 (4%)
Frame = +1
Query: 100 YKNVGLSADELRRRREEEGVQLRKQKREQQLFKRRNVNLPGTNAAGAASQ-EDINISPS- 273
YKN L+ E+RRRREEEG+QLRKQKRE+QLFKRRNV LP + + S +D +IS +
Sbjct: 17 YKNKALNPQEMRRRREEEGIQLRKQKREEQLFKRRNVYLPRNDESMLESPIQDPDISSTV 76
Query: 274 -----DCITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQS-GIVPKFIEFL 435
+ +T DMV ++ +N ++Q+ ATQKFRKLLSKEPNPPID VIQ G+V +F++FL
Sbjct: 77 PIPEEEVVTTDMVQMIFSNNADQQLTATQKFRKLLSKEPNPPIDQVIQKPGVVQRFVKFL 136
Query: 436 TNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWAL 609
++N TLQFEAAWALTNIASG+ T++V++ GAV + + LL+ E+V EQAVWAL
Sbjct: 137 ERNENCTLQFEAAWALTNIASGTFLHTKVVIETGAVPIFIKLLNSEHEDVQEQAVWAL 194
Score = 51.2 bits (117), Expect = 3e-06
Identities = 28/83 (33%), Positives = 47/83 (56%)
Frame = +1
Query: 361 LSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGA 540
LS PN I AVI SG+ + +E L H + + A A+ NI +G QT+++++ A
Sbjct: 282 LSDGPNDKIQAVIDSGVCRRLVELLM-HNDYKVVSPALRAVGNIVTGDDIQTQVILNCSA 340
Query: 541 VNVLVGLLSGSTENVCEQAVWAL 609
+ L+ LLS E++ ++A W +
Sbjct: 341 LPCLLHLLSSPKESIRKEACWTV 363
Score = 44.0 bits (99), Expect = 4e-04
Identities = 25/74 (33%), Positives = 33/74 (44%)
Frame = +1
Query: 388 DAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLS 567
D V+ I+P +E LTN T A WAL+N+ G + +NVL LL
Sbjct: 206 DFVLNCEILPPLLELLTNSNRLTTTRNAVWALSNLCRGKNPPPNFSKVSPCLNVLSRLLF 265
Query: 568 GSTENVCEQAVWAL 609
S +V WAL
Sbjct: 266 SSDPDVLADVCWAL 279
Score = 42.3 bits (95), Expect = 0.001
Identities = 27/73 (36%), Positives = 41/73 (56%), Gaps = 1/73 (1%)
Frame = +1
Query: 394 VIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGS 573
VI++G VP FI+ L N ++ +Q +A WAL NIA ++ V++ + L+ LL+ S
Sbjct: 166 VIETGAVPIFIKLL-NSEHEDVQEQAVWALGNIAGDNAECRDFVLNCEILPPLLELLTNS 224
Query: 574 TE-NVCEQAVWAL 609
AVWAL
Sbjct: 225 NRLTTTRNAVWAL 237
Score = 41.1 bits (92), Expect = 0.003
Identities = 27/73 (36%), Positives = 38/73 (52%), Gaps = 1/73 (1%)
Frame = +1
Query: 385 IDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSS-GQTRIVVDYGAVNVLVGL 561
I AVI + I P IE L + T + EAAWA+TN SG + Q R +V G + L L
Sbjct: 374 IQAVIDANIFPVLIEILQKAEFRTRK-EAAWAITNATSGGTPEQIRYLVALGCIKPLCDL 432
Query: 562 LSGSTENVCEQAV 600
L+ + + A+
Sbjct: 433 LTVMDSKIVQVAL 445
Score = 40.3 bits (90), Expect = 0.005
Identities = 18/72 (25%), Positives = 39/72 (54%)
Frame = +1
Query: 394 VIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGS 573
++ +P + L++ K +++ EA W ++NI +G+ Q + V+D VL+ +L +
Sbjct: 335 ILNCSALPCLLHLLSSPKE-SIRKEACWTVSNITAGNRAQIQAVIDANIFPVLIEILQKA 393
Query: 574 TENVCEQAVWAL 609
++A WA+
Sbjct: 394 EFRTRKEAAWAI 405
Score = 29.5 bits (63), Expect = 9.7
Identities = 15/54 (27%), Positives = 28/54 (51%)
Frame = +1
Query: 448 NPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWAL 609
+P + + WAL+ ++ G + + + V+D G LV LL + V A+ A+
Sbjct: 268 DPDVLADVCWALSYLSDGPNDKIQAVIDSGVCRRLVELLMHNDYKVVSPALRAV 321
>AL132795-5|CAI20500.1| 539|Homo sapiens karyopherin alpha 5
(importin alpha 6) protein.
Length = 539
Score = 194 bits (472), Expect = 3e-49
Identities = 100/178 (56%), Positives = 132/178 (74%), Gaps = 8/178 (4%)
Frame = +1
Query: 100 YKNVGLSADELRRRREEEGVQLRKQKREQQLFKRRNVNLPGTNAAGAASQ-EDINISPS- 273
YKN L+ E+RRRREEEG+QLRKQKRE+QLFKRRNV LP + + S +D +IS +
Sbjct: 17 YKNKALNPQEMRRRREEEGIQLRKQKREEQLFKRRNVYLPRNDESMLESPIQDPDISSTV 76
Query: 274 -----DCITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQS-GIVPKFIEFL 435
+ +T DMV ++ +N ++Q+ ATQKFRKLLSKEPNPPID VIQ G+V +F++FL
Sbjct: 77 PIPEEEVVTTDMVQMIFSNNADQQLTATQKFRKLLSKEPNPPIDQVIQKPGVVQRFVKFL 136
Query: 436 TNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWAL 609
++N TLQFEAAWALTNIASG+ T++V++ GAV + + LL+ E+V EQAVWAL
Sbjct: 137 ERNENCTLQFEAAWALTNIASGTFLHTKVVIETGAVPIFIKLLNSEHEDVQEQAVWAL 194
Score = 51.2 bits (117), Expect = 3e-06
Identities = 28/83 (33%), Positives = 47/83 (56%)
Frame = +1
Query: 361 LSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGA 540
LS PN I AVI SG+ + +E L H + + A A+ NI +G QT+++++ A
Sbjct: 282 LSDGPNDKIQAVIDSGVCRRLVELLM-HNDYKVVSPALRAVGNIVTGDDIQTQVILNCSA 340
Query: 541 VNVLVGLLSGSTENVCEQAVWAL 609
+ L+ LLS E++ ++A W +
Sbjct: 341 LPCLLHLLSSPKESIRKEACWTV 363
Score = 44.0 bits (99), Expect = 4e-04
Identities = 25/74 (33%), Positives = 33/74 (44%)
Frame = +1
Query: 388 DAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLS 567
D V+ I+P +E LTN T A WAL+N+ G + +NVL LL
Sbjct: 206 DFVLNCEILPPLLELLTNSNRLTTTRNAVWALSNLCRGKNPPPNFSKVSPCLNVLSRLLF 265
Query: 568 GSTENVCEQAVWAL 609
S +V WAL
Sbjct: 266 SSDPDVLADVCWAL 279
Score = 42.3 bits (95), Expect = 0.001
Identities = 27/73 (36%), Positives = 41/73 (56%), Gaps = 1/73 (1%)
Frame = +1
Query: 394 VIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGS 573
VI++G VP FI+ L N ++ +Q +A WAL NIA ++ V++ + L+ LL+ S
Sbjct: 166 VIETGAVPIFIKLL-NSEHEDVQEQAVWALGNIAGDNAECRDFVLNCEILPPLLELLTNS 224
Query: 574 TE-NVCEQAVWAL 609
AVWAL
Sbjct: 225 NRLTTTRNAVWAL 237
Score = 41.1 bits (92), Expect = 0.003
Identities = 27/73 (36%), Positives = 38/73 (52%), Gaps = 1/73 (1%)
Frame = +1
Query: 385 IDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSS-GQTRIVVDYGAVNVLVGL 561
I AVI + I P IE L + T + EAAWA+TN SG + Q R +V G + L L
Sbjct: 374 IQAVIDANIFPVLIEILQKAEFRTRK-EAAWAITNATSGGTPEQIRYLVALGCIKPLCDL 432
Query: 562 LSGSTENVCEQAV 600
L+ + + A+
Sbjct: 433 LTVMDSKIVQVAL 445
Score = 40.3 bits (90), Expect = 0.005
Identities = 18/72 (25%), Positives = 39/72 (54%)
Frame = +1
Query: 394 VIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGS 573
++ +P + L++ K +++ EA W ++NI +G+ Q + V+D VL+ +L +
Sbjct: 335 ILNCSALPCLLHLLSSPKE-SIRKEACWTVSNITAGNRAQIQAVIDANIFPVLIEILQKA 393
Query: 574 TENVCEQAVWAL 609
++A WA+
Sbjct: 394 EFRTRKEAAWAI 405
Score = 29.5 bits (63), Expect = 9.7
Identities = 15/54 (27%), Positives = 28/54 (51%)
Frame = +1
Query: 448 NPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWAL 609
+P + + WAL+ ++ G + + + V+D G LV LL + V A+ A+
Sbjct: 268 DPDVLADVCWALSYLSDGPNDKIQAVIDSGVCRRLVELLMHNDYKVVSPALRAV 321
>AF005361-1|AAC51868.1| 536|Homo sapiens importin alpha 6 protein.
Length = 536
Score = 193 bits (471), Expect = 4e-49
Identities = 101/178 (56%), Positives = 132/178 (74%), Gaps = 8/178 (4%)
Frame = +1
Query: 100 YKNVGLSADELRRRREEEGVQLRKQKREQQLFKRRNVNLPGTNAAGAASQ-EDINIS--- 267
YKN L+ E+RRRREEEG+QLRKQKRE+QLFKRRNV LP + + S +D +IS
Sbjct: 14 YKNKALNPQEMRRRREEEGIQLRKQKREEQLFKRRNVYLPRNDESMLESPIQDSDISSTV 73
Query: 268 --PSD-CITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQS-GIVPKFIEFL 435
P + +T DMV ++ +N ++Q+ ATQKFRKLLSKEPNPPID VIQ G+V +F++FL
Sbjct: 74 PIPEEGVVTTDMVQMIFSNNADQQLTATQKFRKLLSKEPNPPIDQVIQKPGVVQRFVKFL 133
Query: 436 TNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWAL 609
++N TLQFEAAWALTNIASG+ T++V++ GAV + + LL+ E+V EQAVWAL
Sbjct: 134 ERNENCTLQFEAAWALTNIASGTFLHTKVVIETGAVPIFIKLLNSEHEDVQEQAVWAL 191
Score = 51.2 bits (117), Expect = 3e-06
Identities = 28/83 (33%), Positives = 47/83 (56%)
Frame = +1
Query: 361 LSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGA 540
LS PN I AVI SG+ + +E L H + + A A+ NI +G QT+++++ A
Sbjct: 279 LSDGPNDKIQAVIDSGVCRRLVELLM-HNDYKVVSPALRAVGNIVTGDDIQTQVILNCSA 337
Query: 541 VNVLVGLLSGSTENVCEQAVWAL 609
+ L+ LLS E++ ++A W +
Sbjct: 338 LPCLLHLLSSPKESIRKEACWTV 360
Score = 44.0 bits (99), Expect = 4e-04
Identities = 25/74 (33%), Positives = 33/74 (44%)
Frame = +1
Query: 388 DAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLS 567
D V+ I+P +E LTN T A WAL+N+ G + +NVL LL
Sbjct: 203 DFVLNCEILPPLLELLTNSNRLTTTRNAVWALSNLCRGKNPPPNFSKVSPCLNVLSRLLF 262
Query: 568 GSTENVCEQAVWAL 609
S +V WAL
Sbjct: 263 SSDPDVLADVCWAL 276
Score = 42.3 bits (95), Expect = 0.001
Identities = 27/73 (36%), Positives = 41/73 (56%), Gaps = 1/73 (1%)
Frame = +1
Query: 394 VIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGS 573
VI++G VP FI+ L N ++ +Q +A WAL NIA ++ V++ + L+ LL+ S
Sbjct: 163 VIETGAVPIFIKLL-NSEHEDVQEQAVWALGNIAGDNAECRDFVLNCEILPPLLELLTNS 221
Query: 574 TE-NVCEQAVWAL 609
AVWAL
Sbjct: 222 NRLTTTRNAVWAL 234
Score = 41.1 bits (92), Expect = 0.003
Identities = 27/73 (36%), Positives = 38/73 (52%), Gaps = 1/73 (1%)
Frame = +1
Query: 385 IDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSS-GQTRIVVDYGAVNVLVGL 561
I AVI + I P IE L + T + EAAWA+TN SG + Q R +V G + L L
Sbjct: 371 IQAVIDANIFPVLIEILQKAEFRTRK-EAAWAITNATSGGTPEQIRYLVALGCIKPLCDL 429
Query: 562 LSGSTENVCEQAV 600
L+ + + A+
Sbjct: 430 LTVMDSKIVQVAL 442
Score = 40.3 bits (90), Expect = 0.005
Identities = 18/72 (25%), Positives = 39/72 (54%)
Frame = +1
Query: 394 VIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGS 573
++ +P + L++ K +++ EA W ++NI +G+ Q + V+D VL+ +L +
Sbjct: 332 ILNCSALPCLLHLLSSPKE-SIRKEACWTVSNITAGNRAQIQAVIDANIFPVLIEILQKA 390
Query: 574 TENVCEQAVWAL 609
++A WA+
Sbjct: 391 EFRTRKEAAWAI 402
Score = 29.5 bits (63), Expect = 9.7
Identities = 15/54 (27%), Positives = 28/54 (51%)
Frame = +1
Query: 448 NPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWAL 609
+P + + WAL+ ++ G + + + V+D G LV LL + V A+ A+
Sbjct: 265 DPDVLADVCWALSYLSDGPNDKIQAVIDSGVCRRLVELLMHNDYKVVSPALRAV 318
>S75295-1|AAC60648.1| 538|Homo sapiens nucleoprotein interactor 1
protein.
Length = 538
Score = 189 bits (460), Expect = 8e-48
Identities = 99/180 (55%), Positives = 126/180 (70%), Gaps = 10/180 (5%)
Frame = +1
Query: 100 YKNVGLSADELRRRREEEGVQLRKQKREQQLFKRRNV---------NLPGTNAAGAASQE 252
YKN L+ DE+RRRREEEG+QLRKQKRE+QLFKRRNV + A
Sbjct: 14 YKNKSLNPDEMRRRREEEGLQLRKQKREEQLFKRRNVATAEEETEEEVMSDGGFHEAQIS 73
Query: 253 DINISPSDCITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQS-GIVPKFIE 429
++ ++P IT DM+ ++ +PE+Q+ ATQKFRKLLSKEPNPPID VI + G+V +F+E
Sbjct: 74 NMEMAPGGVITSDMIEMIFSKSPEQQLSATQKFRKLLSKEPNPPIDEVISTPGVVARFVE 133
Query: 430 FLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWAL 609
FL +N +LQFE+AW LTNIASG+S QTRIV+ AV + + LLS E+V EQAVWAL
Sbjct: 134 FLKRKENCSLQFESAWVLTNIASGNSLQTRIVIQARAVPIFIELLSSEFEDVQEQAVWAL 193
Score = 51.2 bits (117), Expect = 3e-06
Identities = 43/146 (29%), Positives = 72/146 (49%), Gaps = 5/146 (3%)
Frame = +1
Query: 187 QLFKRRNVNLPGTNAAGAASQEDINISPSD---CITPDM-VLAVYLDNPEEQVIATQKFR 354
QLF ++N NA A S SP ++P + VL+ L + V+A +
Sbjct: 218 QLFSKQNRLTMTRNAVWALSNLCRGKSPPPEFAKVSPCLNVLSWLLFVSDTDVLADACWA 277
Query: 355 -KLLSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVD 531
LS PN I AVI +G+ + +E L H + + A A+ NI +G QT+++++
Sbjct: 278 LSYLSDGPNDKIQAVIDAGVCRRLVELLM-HNDYKVVSPALRAVGNIVTGDDIQTQVILN 336
Query: 532 YGAVNVLVGLLSGSTENVCEQAVWAL 609
A+ L+ LLS E++ ++A W +
Sbjct: 337 CSALQSLLHLLSSPKESIKKEACWTI 362
Score = 41.9 bits (94), Expect = 0.002
Identities = 23/74 (31%), Positives = 33/74 (44%)
Frame = +1
Query: 388 DAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLS 567
D V+ I+P ++ + T+ A WAL+N+ G S +NVL LL
Sbjct: 205 DYVLDCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKSPPPEFAKVSPCLNVLSWLLF 264
Query: 568 GSTENVCEQAVWAL 609
S +V A WAL
Sbjct: 265 VSDTDVLADACWAL 278
Score = 40.3 bits (90), Expect = 0.005
Identities = 25/73 (34%), Positives = 37/73 (50%), Gaps = 1/73 (1%)
Frame = +1
Query: 385 IDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSG-QTRIVVDYGAVNVLVGL 561
I VI + I P I L + T + EAAWA+TN SG S Q + +V+ G + L L
Sbjct: 373 IQTVIDANIFPALISILQTAEFRTRK-EAAWAITNATSGGSAEQIKYLVELGCIKPLCDL 431
Query: 562 LSGSTENVCEQAV 600
L+ + + A+
Sbjct: 432 LTVMDSKIVQVAL 444
Score = 39.9 bits (89), Expect = 0.007
Identities = 28/73 (38%), Positives = 38/73 (52%), Gaps = 1/73 (1%)
Frame = +1
Query: 394 VIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGS 573
VIQ+ VP FIE L++ +Q +A WAL NIA S+ V+D + L+ L S
Sbjct: 165 VIQARAVPIFIELLSSEFED-VQEQAVWALGNIAGDSTMCRDYVLDCNILPPLLQLFSKQ 223
Query: 574 TE-NVCEQAVWAL 609
+ AVWAL
Sbjct: 224 NRLTMTRNAVWAL 236
Score = 37.9 bits (84), Expect = 0.028
Identities = 16/72 (22%), Positives = 37/72 (51%)
Frame = +1
Query: 394 VIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGS 573
++ + + L++ K +++ EA W ++NI +G+ Q + V+D L+ +L +
Sbjct: 334 ILNCSALQSLLHLLSSPKE-SIKKEACWTISNITAGNRAQIQTVIDANIFPALISILQTA 392
Query: 574 TENVCEQAVWAL 609
++A WA+
Sbjct: 393 EFRTRKEAAWAI 404
>BT009843-1|AAP88845.1| 536|Homo sapiens karyopherin alpha 6
(importin alpha 7) protein.
Length = 536
Score = 187 bits (455), Expect = 3e-47
Identities = 101/175 (57%), Positives = 128/175 (73%), Gaps = 5/175 (2%)
Frame = +1
Query: 100 YKNVGLSADELRRRREEEGVQLRKQKREQQLFKRRNVNLPGTNAAGAASQ-EDINISPS- 273
YKN L+ +E+RRRREEEG+QLRKQKREQQLFKRRNV L AA S D +S +
Sbjct: 17 YKNNALNPEEMRRRREEEGIQLRKQKREQQLFKRRNVELINEEAAMFDSLLMDSYVSSTT 76
Query: 274 --DCITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQSG-IVPKFIEFLTNH 444
IT +MV ++ D+ + Q+ TQKFRKLLSKEP+PPID VI + +V +F+EFL +
Sbjct: 77 GESVITREMVEMLFSDDSDLQLATTQKFRKLLSKEPSPPIDEVINTPRVVDRFVEFLKRN 136
Query: 445 KNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWAL 609
+N TLQFEAAWALTNIASG+S QT+IV++ GAV + + LL+ E+V EQAVWAL
Sbjct: 137 ENCTLQFEAAWALTNIASGTSQQTKIVIEAGAVPIFIELLNSDFEDVQEQAVWAL 191
Score = 52.0 bits (119), Expect = 2e-06
Identities = 28/83 (33%), Positives = 47/83 (56%)
Frame = +1
Query: 361 LSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGA 540
LS PN I AVI SG+ + +E L H + + A A+ NI +G QT+++++ A
Sbjct: 279 LSDGPNEKIQAVIDSGVCRRLVELLM-HNDYKVASPALRAVGNIVTGDDIQTQVILNCSA 337
Query: 541 VNVLVGLLSGSTENVCEQAVWAL 609
+ L+ LLS E++ ++A W +
Sbjct: 338 LPCLLHLLSSPKESIRKEACWTI 360
Score = 48.8 bits (111), Expect = 1e-05
Identities = 32/73 (43%), Positives = 42/73 (57%), Gaps = 1/73 (1%)
Frame = +1
Query: 394 VIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGS 573
VI++G VP FIE L N +Q +A WAL NIA SS V++ +N L+ LL+ S
Sbjct: 163 VIEAGAVPIFIELL-NSDFEDVQEQAVWALGNIAGDSSVCRDYVLNCSILNPLLTLLTKS 221
Query: 574 TE-NVCEQAVWAL 609
T + AVWAL
Sbjct: 222 TRLTMTRNAVWAL 234
Score = 41.9 bits (94), Expect = 0.002
Identities = 27/73 (36%), Positives = 38/73 (52%), Gaps = 1/73 (1%)
Frame = +1
Query: 385 IDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSS-GQTRIVVDYGAVNVLVGL 561
I AVI + I P IE L + T + EAAWA+TN SG + Q R +V G + L L
Sbjct: 371 IQAVIDANIFPVLIEILQKAEFRTRK-EAAWAITNATSGGTPEQIRYLVSLGCIKPLCDL 429
Query: 562 LSGSTENVCEQAV 600
L+ + + A+
Sbjct: 430 LTVMDSKIVQVAL 442
Score = 40.7 bits (91), Expect = 0.004
Identities = 18/72 (25%), Positives = 39/72 (54%)
Frame = +1
Query: 394 VIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGS 573
++ +P + L++ K +++ EA W ++NI +G+ Q + V+D VL+ +L +
Sbjct: 332 ILNCSALPCLLHLLSSPKE-SIRKEACWTISNITAGNRAQIQAVIDANIFPVLIEILQKA 390
Query: 574 TENVCEQAVWAL 609
++A WA+
Sbjct: 391 EFRTRKEAAWAI 402
Score = 33.9 bits (74), Expect = 0.45
Identities = 23/83 (27%), Positives = 39/83 (46%)
Frame = +1
Query: 361 LSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGA 540
L + NPP + S +P L + + L +A WAL+ ++ G + + + V+D G
Sbjct: 237 LCRGKNPPPEFAKVSPCLPVLSRLLFSSDSDLLA-DACWALSYLSDGPNEKIQAVIDSGV 295
Query: 541 VNVLVGLLSGSTENVCEQAVWAL 609
LV LL + V A+ A+
Sbjct: 296 CRRLVELLMHNDYKVASPALRAV 318
>BC020520-1|AAH20520.1| 536|Homo sapiens karyopherin alpha 6
(importin alpha 7) protein.
Length = 536
Score = 187 bits (455), Expect = 3e-47
Identities = 101/175 (57%), Positives = 128/175 (73%), Gaps = 5/175 (2%)
Frame = +1
Query: 100 YKNVGLSADELRRRREEEGVQLRKQKREQQLFKRRNVNLPGTNAAGAASQ-EDINISPS- 273
YKN L+ +E+RRRREEEG+QLRKQKREQQLFKRRNV L AA S D +S +
Sbjct: 17 YKNNALNPEEMRRRREEEGIQLRKQKREQQLFKRRNVELINEEAAMFDSLLMDSYVSSTT 76
Query: 274 --DCITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQSG-IVPKFIEFLTNH 444
IT +MV ++ D+ + Q+ TQKFRKLLSKEP+PPID VI + +V +F+EFL +
Sbjct: 77 GESVITREMVEMLFSDDSDLQLATTQKFRKLLSKEPSPPIDEVINTPRVVDRFVEFLKRN 136
Query: 445 KNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWAL 609
+N TLQFEAAWALTNIASG+S QT+IV++ GAV + + LL+ E+V EQAVWAL
Sbjct: 137 ENCTLQFEAAWALTNIASGTSQQTKIVIEAGAVPIFIELLNSDFEDVQEQAVWAL 191
Score = 52.0 bits (119), Expect = 2e-06
Identities = 28/83 (33%), Positives = 47/83 (56%)
Frame = +1
Query: 361 LSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGA 540
LS PN I AVI SG+ + +E L H + + A A+ NI +G QT+++++ A
Sbjct: 279 LSDGPNEKIQAVIDSGVCRRLVELLM-HNDYKVASPALRAVGNIVTGDDIQTQVILNCSA 337
Query: 541 VNVLVGLLSGSTENVCEQAVWAL 609
+ L+ LLS E++ ++A W +
Sbjct: 338 LPCLLHLLSSPKESIRKEACWTI 360
Score = 48.8 bits (111), Expect = 1e-05
Identities = 32/73 (43%), Positives = 42/73 (57%), Gaps = 1/73 (1%)
Frame = +1
Query: 394 VIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGS 573
VI++G VP FIE L N +Q +A WAL NIA SS V++ +N L+ LL+ S
Sbjct: 163 VIEAGAVPIFIELL-NSDFEDVQEQAVWALGNIAGDSSVCRDYVLNCSILNPLLTLLTKS 221
Query: 574 TE-NVCEQAVWAL 609
T + AVWAL
Sbjct: 222 TRLTMTRNAVWAL 234
Score = 41.9 bits (94), Expect = 0.002
Identities = 27/73 (36%), Positives = 38/73 (52%), Gaps = 1/73 (1%)
Frame = +1
Query: 385 IDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSS-GQTRIVVDYGAVNVLVGL 561
I AVI + I P IE L + T + EAAWA+TN SG + Q R +V G + L L
Sbjct: 371 IQAVIDANIFPVLIEILQKAEFRTRK-EAAWAITNATSGGTPEQIRYLVSLGCIKPLCDL 429
Query: 562 LSGSTENVCEQAV 600
L+ + + A+
Sbjct: 430 LTVMDSKIVQVAL 442
Score = 40.7 bits (91), Expect = 0.004
Identities = 18/72 (25%), Positives = 39/72 (54%)
Frame = +1
Query: 394 VIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGS 573
++ +P + L++ K +++ EA W ++NI +G+ Q + V+D VL+ +L +
Sbjct: 332 ILNCSALPCLLHLLSSPKE-SIRKEACWTISNITAGNRAQIQAVIDANIFPVLIEILQKA 390
Query: 574 TENVCEQAVWAL 609
++A WA+
Sbjct: 391 EFRTRKEAAWAI 402
Score = 33.9 bits (74), Expect = 0.45
Identities = 23/83 (27%), Positives = 39/83 (46%)
Frame = +1
Query: 361 LSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGA 540
L + NPP + S +P L + + L +A WAL+ ++ G + + + V+D G
Sbjct: 237 LCRGKNPPPEFAKVSPCLPVLSRLLFSSDSDLLA-DACWALSYLSDGPNEKIQAVIDSGV 295
Query: 541 VNVLVGLLSGSTENVCEQAVWAL 609
LV LL + V A+ A+
Sbjct: 296 CRRLVELLMHNDYKVASPALRAV 318
>AL445248-5|CAH71948.1| 536|Homo sapiens karyopherin alpha 6
(importin alpha 7) protein.
Length = 536
Score = 187 bits (455), Expect = 3e-47
Identities = 101/175 (57%), Positives = 128/175 (73%), Gaps = 5/175 (2%)
Frame = +1
Query: 100 YKNVGLSADELRRRREEEGVQLRKQKREQQLFKRRNVNLPGTNAAGAASQ-EDINISPS- 273
YKN L+ +E+RRRREEEG+QLRKQKREQQLFKRRNV L AA S D +S +
Sbjct: 17 YKNNALNPEEMRRRREEEGIQLRKQKREQQLFKRRNVELINEEAAMFDSLLMDSYVSSTT 76
Query: 274 --DCITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQSG-IVPKFIEFLTNH 444
IT +MV ++ D+ + Q+ TQKFRKLLSKEP+PPID VI + +V +F+EFL +
Sbjct: 77 GESVITREMVEMLFSDDSDLQLATTQKFRKLLSKEPSPPIDEVINTPRVVDRFVEFLKRN 136
Query: 445 KNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWAL 609
+N TLQFEAAWALTNIASG+S QT+IV++ GAV + + LL+ E+V EQAVWAL
Sbjct: 137 ENCTLQFEAAWALTNIASGTSQQTKIVIEAGAVPIFIELLNSDFEDVQEQAVWAL 191
Score = 52.0 bits (119), Expect = 2e-06
Identities = 28/83 (33%), Positives = 47/83 (56%)
Frame = +1
Query: 361 LSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGA 540
LS PN I AVI SG+ + +E L H + + A A+ NI +G QT+++++ A
Sbjct: 279 LSDGPNEKIQAVIDSGVCRRLVELLM-HNDYKVASPALRAVGNIVTGDDIQTQVILNCSA 337
Query: 541 VNVLVGLLSGSTENVCEQAVWAL 609
+ L+ LLS E++ ++A W +
Sbjct: 338 LPCLLHLLSSPKESIRKEACWTI 360
Score = 48.8 bits (111), Expect = 1e-05
Identities = 32/73 (43%), Positives = 42/73 (57%), Gaps = 1/73 (1%)
Frame = +1
Query: 394 VIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGS 573
VI++G VP FIE L N +Q +A WAL NIA SS V++ +N L+ LL+ S
Sbjct: 163 VIEAGAVPIFIELL-NSDFEDVQEQAVWALGNIAGDSSVCRDYVLNCSILNPLLTLLTKS 221
Query: 574 TE-NVCEQAVWAL 609
T + AVWAL
Sbjct: 222 TRLTMTRNAVWAL 234
Score = 41.9 bits (94), Expect = 0.002
Identities = 27/73 (36%), Positives = 38/73 (52%), Gaps = 1/73 (1%)
Frame = +1
Query: 385 IDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSS-GQTRIVVDYGAVNVLVGL 561
I AVI + I P IE L + T + EAAWA+TN SG + Q R +V G + L L
Sbjct: 371 IQAVIDANIFPVLIEILQKAEFRTRK-EAAWAITNATSGGTPEQIRYLVSLGCIKPLCDL 429
Query: 562 LSGSTENVCEQAV 600
L+ + + A+
Sbjct: 430 LTVMDSKIVQVAL 442
Score = 40.7 bits (91), Expect = 0.004
Identities = 18/72 (25%), Positives = 39/72 (54%)
Frame = +1
Query: 394 VIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGS 573
++ +P + L++ K +++ EA W ++NI +G+ Q + V+D VL+ +L +
Sbjct: 332 ILNCSALPCLLHLLSSPKE-SIRKEACWTISNITAGNRAQIQAVIDANIFPVLIEILQKA 390
Query: 574 TENVCEQAVWAL 609
++A WA+
Sbjct: 391 EFRTRKEAAWAI 402
Score = 33.9 bits (74), Expect = 0.45
Identities = 23/83 (27%), Positives = 39/83 (46%)
Frame = +1
Query: 361 LSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGA 540
L + NPP + S +P L + + L +A WAL+ ++ G + + + V+D G
Sbjct: 237 LCRGKNPPPEFAKVSPCLPVLSRLLFSSDSDLLA-DACWALSYLSDGPNEKIQAVIDSGV 295
Query: 541 VNVLVGLLSGSTENVCEQAVWAL 609
LV LL + V A+ A+
Sbjct: 296 CRRLVELLMHNDYKVASPALRAV 318
>AL049795-3|CAI22056.1| 536|Homo sapiens karyopherin alpha 6
(importin alpha 7) protein.
Length = 536
Score = 187 bits (455), Expect = 3e-47
Identities = 101/175 (57%), Positives = 128/175 (73%), Gaps = 5/175 (2%)
Frame = +1
Query: 100 YKNVGLSADELRRRREEEGVQLRKQKREQQLFKRRNVNLPGTNAAGAASQ-EDINISPS- 273
YKN L+ +E+RRRREEEG+QLRKQKREQQLFKRRNV L AA S D +S +
Sbjct: 17 YKNNALNPEEMRRRREEEGIQLRKQKREQQLFKRRNVELINEEAAMFDSLLMDSYVSSTT 76
Query: 274 --DCITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQSG-IVPKFIEFLTNH 444
IT +MV ++ D+ + Q+ TQKFRKLLSKEP+PPID VI + +V +F+EFL +
Sbjct: 77 GESVITREMVEMLFSDDSDLQLATTQKFRKLLSKEPSPPIDEVINTPRVVDRFVEFLKRN 136
Query: 445 KNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWAL 609
+N TLQFEAAWALTNIASG+S QT+IV++ GAV + + LL+ E+V EQAVWAL
Sbjct: 137 ENCTLQFEAAWALTNIASGTSQQTKIVIEAGAVPIFIELLNSDFEDVQEQAVWAL 191
Score = 52.0 bits (119), Expect = 2e-06
Identities = 28/83 (33%), Positives = 47/83 (56%)
Frame = +1
Query: 361 LSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGA 540
LS PN I AVI SG+ + +E L H + + A A+ NI +G QT+++++ A
Sbjct: 279 LSDGPNEKIQAVIDSGVCRRLVELLM-HNDYKVASPALRAVGNIVTGDDIQTQVILNCSA 337
Query: 541 VNVLVGLLSGSTENVCEQAVWAL 609
+ L+ LLS E++ ++A W +
Sbjct: 338 LPCLLHLLSSPKESIRKEACWTI 360
Score = 48.8 bits (111), Expect = 1e-05
Identities = 32/73 (43%), Positives = 42/73 (57%), Gaps = 1/73 (1%)
Frame = +1
Query: 394 VIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGS 573
VI++G VP FIE L N +Q +A WAL NIA SS V++ +N L+ LL+ S
Sbjct: 163 VIEAGAVPIFIELL-NSDFEDVQEQAVWALGNIAGDSSVCRDYVLNCSILNPLLTLLTKS 221
Query: 574 TE-NVCEQAVWAL 609
T + AVWAL
Sbjct: 222 TRLTMTRNAVWAL 234
Score = 41.9 bits (94), Expect = 0.002
Identities = 27/73 (36%), Positives = 38/73 (52%), Gaps = 1/73 (1%)
Frame = +1
Query: 385 IDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSS-GQTRIVVDYGAVNVLVGL 561
I AVI + I P IE L + T + EAAWA+TN SG + Q R +V G + L L
Sbjct: 371 IQAVIDANIFPVLIEILQKAEFRTRK-EAAWAITNATSGGTPEQIRYLVSLGCIKPLCDL 429
Query: 562 LSGSTENVCEQAV 600
L+ + + A+
Sbjct: 430 LTVMDSKIVQVAL 442
Score = 40.7 bits (91), Expect = 0.004
Identities = 18/72 (25%), Positives = 39/72 (54%)
Frame = +1
Query: 394 VIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGS 573
++ +P + L++ K +++ EA W ++NI +G+ Q + V+D VL+ +L +
Sbjct: 332 ILNCSALPCLLHLLSSPKE-SIRKEACWTISNITAGNRAQIQAVIDANIFPVLIEILQKA 390
Query: 574 TENVCEQAVWAL 609
++A WA+
Sbjct: 391 EFRTRKEAAWAI 402
Score = 33.9 bits (74), Expect = 0.45
Identities = 23/83 (27%), Positives = 39/83 (46%)
Frame = +1
Query: 361 LSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGA 540
L + NPP + S +P L + + L +A WAL+ ++ G + + + V+D G
Sbjct: 237 LCRGKNPPPEFAKVSPCLPVLSRLLFSSDSDLLA-DACWALSYLSDGPNEKIQAVIDSGV 295
Query: 541 VNVLVGLLSGSTENVCEQAVWAL 609
LV LL + V A+ A+
Sbjct: 296 CRRLVELLMHNDYKVASPALRAV 318
>AF060543-1|AAC15233.1| 536|Homo sapiens importin alpha 7 subunit
protein.
Length = 536
Score = 187 bits (455), Expect = 3e-47
Identities = 101/175 (57%), Positives = 128/175 (73%), Gaps = 5/175 (2%)
Frame = +1
Query: 100 YKNVGLSADELRRRREEEGVQLRKQKREQQLFKRRNVNLPGTNAAGAASQ-EDINISPS- 273
YKN L+ +E+RRRREEEG+QLRKQKREQQLFKRRNV L AA S D +S +
Sbjct: 17 YKNNALNPEEMRRRREEEGIQLRKQKREQQLFKRRNVELINEEAAMFDSLLMDSYVSSTT 76
Query: 274 --DCITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQSG-IVPKFIEFLTNH 444
IT +MV ++ D+ + Q+ TQKFRKLLSKEP+PPID VI + +V +F+EFL +
Sbjct: 77 GESVITREMVEMLFSDDSDLQLATTQKFRKLLSKEPSPPIDEVINTPRVVDRFVEFLKRN 136
Query: 445 KNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWAL 609
+N TLQFEAAWALTNIASG+S QT+IV++ GAV + + LL+ E+V EQAVWAL
Sbjct: 137 ENCTLQFEAAWALTNIASGTSQQTKIVIEAGAVPIFIELLNSDFEDVQEQAVWAL 191
Score = 52.0 bits (119), Expect = 2e-06
Identities = 28/83 (33%), Positives = 47/83 (56%)
Frame = +1
Query: 361 LSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGA 540
LS PN I AVI SG+ + +E L H + + A A+ NI +G QT+++++ A
Sbjct: 279 LSDGPNEKIQAVIDSGVCRRLVELLM-HNDYKVASPALRAVGNIVTGDDIQTQVILNCSA 337
Query: 541 VNVLVGLLSGSTENVCEQAVWAL 609
+ L+ LLS E++ ++A W +
Sbjct: 338 LPCLLHLLSSPKESIRKEACWTI 360
Score = 48.8 bits (111), Expect = 1e-05
Identities = 32/73 (43%), Positives = 42/73 (57%), Gaps = 1/73 (1%)
Frame = +1
Query: 394 VIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGS 573
VI++G VP FIE L N +Q +A WAL NIA SS V++ +N L+ LL+ S
Sbjct: 163 VIEAGAVPIFIELL-NSDFEDVQEQAVWALGNIAGDSSVCRDYVLNCSILNPLLTLLTKS 221
Query: 574 TE-NVCEQAVWAL 609
T + AVWAL
Sbjct: 222 TRLTMTRNAVWAL 234
Score = 41.9 bits (94), Expect = 0.002
Identities = 27/73 (36%), Positives = 38/73 (52%), Gaps = 1/73 (1%)
Frame = +1
Query: 385 IDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSS-GQTRIVVDYGAVNVLVGL 561
I AVI + I P IE L + T + EAAWA+TN SG + Q R +V G + L L
Sbjct: 371 IQAVIDANIFPVLIEILQKAEFRTRK-EAAWAITNATSGGTPEQIRYLVSLGCIKPLCDL 429
Query: 562 LSGSTENVCEQAV 600
L+ + + A+
Sbjct: 430 LTVMDSKIVQVAL 442
Score = 40.7 bits (91), Expect = 0.004
Identities = 18/72 (25%), Positives = 39/72 (54%)
Frame = +1
Query: 394 VIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGS 573
++ +P + L++ K +++ EA W ++NI +G+ Q + V+D VL+ +L +
Sbjct: 332 ILNCSALPCLLHLLSSPKE-SIRKEACWTISNITAGNRAQIQAVIDANIFPVLIEILQKA 390
Query: 574 TENVCEQAVWAL 609
++A WA+
Sbjct: 391 EFRTRKEAAWAI 402
Score = 33.9 bits (74), Expect = 0.45
Identities = 23/83 (27%), Positives = 39/83 (46%)
Frame = +1
Query: 361 LSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGA 540
L + NPP + S +P L + + L +A WAL+ ++ G + + + V+D G
Sbjct: 237 LCRGKNPPPEFAKVSPCLPVLSRLLFSSDSDLLA-DACWALSYLSDGPNEKIQAVIDSGV 295
Query: 541 VNVLVGLLSGSTENVCEQAVWAL 609
LV LL + V A+ A+
Sbjct: 296 CRRLVELLMHNDYKVASPALRAV 318
>BT006665-1|AAP35311.1| 529|Homo sapiens karyopherin alpha 2 (RAG
cohort 1, importin alpha 1) protein.
Length = 529
Score = 159 bits (385), Expect = 9e-39
Identities = 79/172 (45%), Positives = 110/172 (63%)
Frame = +1
Query: 94 HRYKNVGLSADELRRRREEEGVQLRKQKREQQLFKRRNVNLPGTNAAGAASQEDINISPS 273
HR+KN G + E+RRRR E V+LRK K++ Q+ KRRNV+ +A + N
Sbjct: 15 HRFKNKGKDSTEMRRRRIEVNVELRKAKKDDQMLKRRNVSSFPDDATSPLQENRNNQGTV 74
Query: 274 DCITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQSGIVPKFIEFLTNHKNP 453
+ D+V + N E Q+ ATQ RKLLS+E PPID +I++G++PKF+ FL
Sbjct: 75 NWSVDDIVKGINSSNVENQLQATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGRTDCS 134
Query: 454 TLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWAL 609
+QFE+AWALTNIASG+S QT++VVD GA+ + LL+ ++ EQAVWAL
Sbjct: 135 PIQFESAWALTNIASGTSEQTKVVVDGGAIPAFISLLASPHAHISEQAVWAL 186
Score = 59.7 bits (138), Expect = 8e-09
Identities = 35/111 (31%), Positives = 63/111 (56%), Gaps = 1/111 (0%)
Frame = +1
Query: 280 ITPDMVLAVYLDNPEEQVIATQKFR-KLLSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPT 456
I P +V ++ D+PE V+A + L+ PN I V+++G+VP+ ++ L + P
Sbjct: 252 ILPTLVRLLHHDDPE--VLADTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGASELPI 309
Query: 457 LQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWAL 609
+ A A+ NI +G+ QT++V+D GA+ V LL+ N+ ++A W +
Sbjct: 310 VT-PALRAIGNIVTGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWTM 359
Score = 46.4 bits (105), Expect = 8e-05
Identities = 28/82 (34%), Positives = 44/82 (53%)
Frame = +1
Query: 364 SKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAV 543
+K P PPIDAV Q I+P + L +H +P + + WA++ + G + + +VV G V
Sbjct: 239 NKNPAPPIDAVEQ--ILPTLVRLL-HHDDPEVLADTCWAISYLTDGPNERIGMVVKTGVV 295
Query: 544 NVLVGLLSGSTENVCEQAVWAL 609
LV LL S + A+ A+
Sbjct: 296 PQLVKLLGASELPIVTPALRAI 317
Score = 41.9 bits (94), Expect = 0.002
Identities = 22/58 (37%), Positives = 33/58 (56%)
Frame = +1
Query: 394 VIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLS 567
V+ G +P FI L + + + +A WAL NIA S +V+ YGAV+ L+ LL+
Sbjct: 158 VVDGGAIPAFISLLAS-PHAHISEQAVWALGNIAGDGSVFRDLVIKYGAVDPLLALLA 214
Score = 35.1 bits (77), Expect = 0.19
Identities = 22/68 (32%), Positives = 33/68 (48%), Gaps = 1/68 (1%)
Frame = +1
Query: 385 IDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSS-GQTRIVVDYGAVNVLVGL 561
I V+ G+VP + L+ T Q EA WA+TN SG + Q +V G + L+ L
Sbjct: 370 IQQVVNHGLVPFLVSVLSKADFKT-QKEAVWAVTNYTSGGTVEQIVYLVHCGIIEPLMNL 428
Query: 562 LSGSTENV 585
L+ +
Sbjct: 429 LTAKDTKI 436
>BC005978-1|AAH05978.1| 529|Homo sapiens karyopherin alpha 2 (RAG
cohort 1, importin alpha 1) protein.
Length = 529
Score = 159 bits (385), Expect = 9e-39
Identities = 79/172 (45%), Positives = 110/172 (63%)
Frame = +1
Query: 94 HRYKNVGLSADELRRRREEEGVQLRKQKREQQLFKRRNVNLPGTNAAGAASQEDINISPS 273
HR+KN G + E+RRRR E V+LRK K++ Q+ KRRNV+ +A + N
Sbjct: 15 HRFKNKGKDSTEMRRRRIEVNVELRKAKKDDQMLKRRNVSSFPDDATSPLQENRNNQGTV 74
Query: 274 DCITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQSGIVPKFIEFLTNHKNP 453
+ D+V + N E Q+ ATQ RKLLS+E PPID +I++G++PKF+ FL
Sbjct: 75 NWSVDDIVKGINSSNVENQLQATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGRTDCS 134
Query: 454 TLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWAL 609
+QFE+AWALTNIASG+S QT++VVD GA+ + LL+ ++ EQAVWAL
Sbjct: 135 PIQFESAWALTNIASGTSEQTKVVVDGGAIPAFISLLASPHAHISEQAVWAL 186
Score = 59.7 bits (138), Expect = 8e-09
Identities = 35/111 (31%), Positives = 63/111 (56%), Gaps = 1/111 (0%)
Frame = +1
Query: 280 ITPDMVLAVYLDNPEEQVIATQKFR-KLLSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPT 456
I P +V ++ D+PE V+A + L+ PN I V+++G+VP+ ++ L + P
Sbjct: 252 ILPTLVRLLHHDDPE--VLADTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGASELPI 309
Query: 457 LQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWAL 609
+ A A+ NI +G+ QT++V+D GA+ V LL+ N+ ++A W +
Sbjct: 310 VT-PALRAIGNIVTGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWTM 359
Score = 46.4 bits (105), Expect = 8e-05
Identities = 28/82 (34%), Positives = 44/82 (53%)
Frame = +1
Query: 364 SKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAV 543
+K P PPIDAV Q I+P + L +H +P + + WA++ + G + + +VV G V
Sbjct: 239 NKNPAPPIDAVEQ--ILPTLVRLL-HHDDPEVLADTCWAISYLTDGPNERIGMVVKTGVV 295
Query: 544 NVLVGLLSGSTENVCEQAVWAL 609
LV LL S + A+ A+
Sbjct: 296 PQLVKLLGASELPIVTPALRAI 317
Score = 41.9 bits (94), Expect = 0.002
Identities = 22/58 (37%), Positives = 33/58 (56%)
Frame = +1
Query: 394 VIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLS 567
V+ G +P FI L + + + +A WAL NIA S +V+ YGAV+ L+ LL+
Sbjct: 158 VVDGGAIPAFISLLAS-PHAHISEQAVWALGNIAGDGSVFRDLVIKYGAVDPLLALLA 214
Score = 35.1 bits (77), Expect = 0.19
Identities = 22/68 (32%), Positives = 33/68 (48%), Gaps = 1/68 (1%)
Frame = +1
Query: 385 IDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSS-GQTRIVVDYGAVNVLVGL 561
I V+ G+VP + L+ T Q EA WA+TN SG + Q +V G + L+ L
Sbjct: 370 IQQVVNHGLVPFLVSVLSKADFKT-QKEAVWAVTNYTSGGTVEQIVYLVHCGIIEPLMNL 428
Query: 562 LSGSTENV 585
L+ +
Sbjct: 429 LTAKDTKI 436
>U28386-1|AAA69957.1| 529|Homo sapiens hSRP1alpha protein.
Length = 529
Score = 157 bits (381), Expect = 3e-38
Identities = 79/172 (45%), Positives = 109/172 (63%)
Frame = +1
Query: 94 HRYKNVGLSADELRRRREEEGVQLRKQKREQQLFKRRNVNLPGTNAAGAASQEDINISPS 273
HR+KN G + E+RRRR E V+LRK K++ Q+ KRRNV+ +A + N
Sbjct: 15 HRFKNKGKDSTEMRRRRIEVNVELRKAKKDDQMLKRRNVSSFPDDATSPLQENRNNQGTV 74
Query: 274 DCITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQSGIVPKFIEFLTNHKNP 453
+ D+V + N E Q+ ATQ RKLLS+E PPID +I++G++PKF+ FL
Sbjct: 75 NWSVDDIVKGINSSNVENQLQATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGRTDCS 134
Query: 454 TLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWAL 609
+QFE+AWALTNIASG+S QT+ VVD GA+ + LL+ ++ EQAVWAL
Sbjct: 135 PIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWAL 186
Score = 59.7 bits (138), Expect = 8e-09
Identities = 35/111 (31%), Positives = 63/111 (56%), Gaps = 1/111 (0%)
Frame = +1
Query: 280 ITPDMVLAVYLDNPEEQVIATQKFR-KLLSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPT 456
I P +V ++ D+PE V+A + L+ PN I V+++G+VP+ ++ L + P
Sbjct: 252 ILPTLVRLLHHDDPE--VLADTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGASELPI 309
Query: 457 LQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWAL 609
+ A A+ NI +G+ QT++V+D GA+ V LL+ N+ ++A W +
Sbjct: 310 VT-PALRAIGNIVTGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWTM 359
Score = 46.4 bits (105), Expect = 8e-05
Identities = 28/82 (34%), Positives = 44/82 (53%)
Frame = +1
Query: 364 SKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAV 543
+K P PPIDAV Q I+P + L +H +P + + WA++ + G + + +VV G V
Sbjct: 239 NKNPAPPIDAVEQ--ILPTLVRLL-HHDDPEVLADTCWAISYLTDGPNERIGMVVKTGVV 295
Query: 544 NVLVGLLSGSTENVCEQAVWAL 609
LV LL S + A+ A+
Sbjct: 296 PQLVKLLGASELPIVTPALRAI 317
Score = 43.6 bits (98), Expect = 6e-04
Identities = 23/59 (38%), Positives = 34/59 (57%)
Frame = +1
Query: 391 AVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLS 567
AV+ G +P FI L + + + +A WAL NIA S +V+ YGAV+ L+ LL+
Sbjct: 157 AVVDGGAIPAFISLLAS-PHAHISEQAVWALGNIAGDGSVFRDLVIKYGAVDPLLALLA 214
Score = 35.1 bits (77), Expect = 0.19
Identities = 22/68 (32%), Positives = 33/68 (48%), Gaps = 1/68 (1%)
Frame = +1
Query: 385 IDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSS-GQTRIVVDYGAVNVLVGL 561
I V+ G+VP + L+ T Q EA WA+TN SG + Q +V G + L+ L
Sbjct: 370 IQQVVNHGLVPFLVSVLSKADFKT-QKEAVWAVTNYTSGGTVEQIVYLVHCGIIEPLMNL 428
Query: 562 LSGSTENV 585
L+ +
Sbjct: 429 LTAKDTKI 436
>U09559-1|AAA65700.1| 529|Homo sapiens Rch1 protein.
Length = 529
Score = 157 bits (381), Expect = 3e-38
Identities = 79/172 (45%), Positives = 109/172 (63%)
Frame = +1
Query: 94 HRYKNVGLSADELRRRREEEGVQLRKQKREQQLFKRRNVNLPGTNAAGAASQEDINISPS 273
HR+KN G + E+RRRR E V+LRK K++ Q+ KRRNV+ +A + N
Sbjct: 15 HRFKNKGKDSTEMRRRRIEVNVELRKAKKDDQMLKRRNVSSFPDDATSPLQENRNNQGTV 74
Query: 274 DCITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQSGIVPKFIEFLTNHKNP 453
+ D+V + N E Q+ ATQ RKLLS+E PPID +I++G++PKF+ FL
Sbjct: 75 NWSVDDIVKGINSSNVENQLQATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGRTDCS 134
Query: 454 TLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWAL 609
+QFE+AWALTNIASG+S QT+ VVD GA+ + LL+ ++ EQAVWAL
Sbjct: 135 PIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWAL 186
Score = 59.7 bits (138), Expect = 8e-09
Identities = 35/111 (31%), Positives = 63/111 (56%), Gaps = 1/111 (0%)
Frame = +1
Query: 280 ITPDMVLAVYLDNPEEQVIATQKFR-KLLSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPT 456
I P +V ++ D+PE V+A + L+ PN I V+++G+VP+ ++ L + P
Sbjct: 252 ILPTLVRLLHHDDPE--VLADTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGASELPI 309
Query: 457 LQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWAL 609
+ A A+ NI +G+ QT++V+D GA+ V LL+ N+ ++A W +
Sbjct: 310 VT-PALRAIGNIVTGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWTM 359
Score = 46.4 bits (105), Expect = 8e-05
Identities = 28/82 (34%), Positives = 44/82 (53%)
Frame = +1
Query: 364 SKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAV 543
+K P PPIDAV Q I+P + L +H +P + + WA++ + G + + +VV G V
Sbjct: 239 NKNPAPPIDAVEQ--ILPTLVRLL-HHDDPEVLADTCWAISYLTDGPNERIGMVVKTGVV 295
Query: 544 NVLVGLLSGSTENVCEQAVWAL 609
LV LL S + A+ A+
Sbjct: 296 PQLVKLLGASELPIVTPALRAI 317
Score = 43.6 bits (98), Expect = 6e-04
Identities = 23/59 (38%), Positives = 34/59 (57%)
Frame = +1
Query: 391 AVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLS 567
AV+ G +P FI L + + + +A WAL NIA S +V+ YGAV+ L+ LL+
Sbjct: 157 AVVDGGAIPAFISLLAS-PHAHISEQAVWALGNIAGDGSVFRDLVIKYGAVDPLLALLA 214
Score = 35.1 bits (77), Expect = 0.19
Identities = 22/68 (32%), Positives = 33/68 (48%), Gaps = 1/68 (1%)
Frame = +1
Query: 385 IDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSS-GQTRIVVDYGAVNVLVGL 561
I V+ G+VP + L+ T Q EA WA+TN SG + Q +V G + L+ L
Sbjct: 370 IQQVVNHGLVPFLVSVLSKADFKT-QKEAVWAVTNYTSGGTVEQIVYLVHCGIIEPLMNL 428
Query: 562 LSGSTENV 585
L+ +
Sbjct: 429 LTAKDTKI 436
>BC053343-1|AAH53343.1| 529|Homo sapiens karyopherin alpha 2 (RAG
cohort 1, importin alpha 1) protein.
Length = 529
Score = 157 bits (381), Expect = 3e-38
Identities = 79/172 (45%), Positives = 109/172 (63%)
Frame = +1
Query: 94 HRYKNVGLSADELRRRREEEGVQLRKQKREQQLFKRRNVNLPGTNAAGAASQEDINISPS 273
HR+KN G + E+RRRR E V+LRK K++ Q+ KRRNV+ +A + N
Sbjct: 15 HRFKNKGKDSTEMRRRRIEVNVELRKAKKDDQMLKRRNVSSFPDDATSPLQENRNNQGTV 74
Query: 274 DCITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQSGIVPKFIEFLTNHKNP 453
+ D+V + N E Q+ ATQ RKLLS+E PPID +I++G++PKF+ FL
Sbjct: 75 NWSVDDIVKGINSSNVENQLQATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGRTDCS 134
Query: 454 TLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWAL 609
+QFE+AWALTNIASG+S QT+ VVD GA+ + LL+ ++ EQAVWAL
Sbjct: 135 PIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWAL 186
Score = 59.7 bits (138), Expect = 8e-09
Identities = 35/111 (31%), Positives = 63/111 (56%), Gaps = 1/111 (0%)
Frame = +1
Query: 280 ITPDMVLAVYLDNPEEQVIATQKFR-KLLSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPT 456
I P +V ++ D+PE V+A + L+ PN I V+++G+VP+ ++ L + P
Sbjct: 252 ILPTLVRLLHHDDPE--VLADTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGASELPI 309
Query: 457 LQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWAL 609
+ A A+ NI +G+ QT++V+D GA+ V LL+ N+ ++A W +
Sbjct: 310 VT-PALRAIGNIVTGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWTM 359
Score = 46.4 bits (105), Expect = 8e-05
Identities = 28/82 (34%), Positives = 44/82 (53%)
Frame = +1
Query: 364 SKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAV 543
+K P PPIDAV Q I+P + L +H +P + + WA++ + G + + +VV G V
Sbjct: 239 NKNPAPPIDAVEQ--ILPTLVRLL-HHDDPEVLADTCWAISYLTDGPNERIGMVVKTGVV 295
Query: 544 NVLVGLLSGSTENVCEQAVWAL 609
LV LL S + A+ A+
Sbjct: 296 PQLVKLLGASELPIVTPALRAI 317
Score = 43.6 bits (98), Expect = 6e-04
Identities = 23/59 (38%), Positives = 34/59 (57%)
Frame = +1
Query: 391 AVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLS 567
AV+ G +P FI L + + + +A WAL NIA S +V+ YGAV+ L+ LL+
Sbjct: 157 AVVDGGAIPAFISLLAS-PHAHISEQAVWALGNIAGDGSVFRDLVIKYGAVDPLLALLA 214
Score = 35.1 bits (77), Expect = 0.19
Identities = 22/68 (32%), Positives = 33/68 (48%), Gaps = 1/68 (1%)
Frame = +1
Query: 385 IDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSS-GQTRIVVDYGAVNVLVGL 561
I V+ G+VP + L+ T Q EA WA+TN SG + Q +V G + L+ L
Sbjct: 370 IQQVVNHGLVPFLVSVLSKADFKT-QKEAVWAVTNYTSGGTVEQIVYLVHCGIIEPLMNL 428
Query: 562 LSGSTENV 585
L+ +
Sbjct: 429 LTAKDTKI 436
>AJ303086-1|CAC83080.1| 529|Homo sapiens karyopherin alpha 2
protein.
Length = 529
Score = 157 bits (381), Expect = 3e-38
Identities = 79/172 (45%), Positives = 109/172 (63%)
Frame = +1
Query: 94 HRYKNVGLSADELRRRREEEGVQLRKQKREQQLFKRRNVNLPGTNAAGAASQEDINISPS 273
HR+KN G + E+RRRR E V+LRK K++ Q+ KRRNV+ +A + N
Sbjct: 15 HRFKNKGKDSTEMRRRRIEVNVELRKAKKDDQMLKRRNVSSFPDDATSPLQENRNNQGTV 74
Query: 274 DCITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQSGIVPKFIEFLTNHKNP 453
+ D+V + N E Q+ ATQ RKLLS+E PPID +I++G++PKF+ FL
Sbjct: 75 NWSVDDIVKGINSSNVENQLQATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGRTDCS 134
Query: 454 TLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWAL 609
+QFE+AWALTNIASG+S QT+ VVD GA+ + LL+ ++ EQAVWAL
Sbjct: 135 PIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWAL 186
Score = 59.7 bits (138), Expect = 8e-09
Identities = 35/111 (31%), Positives = 63/111 (56%), Gaps = 1/111 (0%)
Frame = +1
Query: 280 ITPDMVLAVYLDNPEEQVIATQKFR-KLLSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPT 456
I P +V ++ D+PE V+A + L+ PN I V+++G+VP+ ++ L + P
Sbjct: 252 ILPTLVRLLHHDDPE--VLADTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGASELPI 309
Query: 457 LQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWAL 609
+ A A+ NI +G+ QT++V+D GA+ V LL+ N+ ++A W +
Sbjct: 310 VT-PALRAIGNIVTGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWTM 359
Score = 46.4 bits (105), Expect = 8e-05
Identities = 28/82 (34%), Positives = 44/82 (53%)
Frame = +1
Query: 364 SKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAV 543
+K P PPIDAV Q I+P + L +H +P + + WA++ + G + + +VV G V
Sbjct: 239 NKNPAPPIDAVEQ--ILPTLVRLL-HHDDPEVLADTCWAISYLTDGPNERIGMVVKTGVV 295
Query: 544 NVLVGLLSGSTENVCEQAVWAL 609
LV LL S + A+ A+
Sbjct: 296 PQLVKLLGASELPIVTPALRAI 317
Score = 43.6 bits (98), Expect = 6e-04
Identities = 23/59 (38%), Positives = 34/59 (57%)
Frame = +1
Query: 391 AVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLS 567
AV+ G +P FI L + + + +A WAL NIA S +V+ YGAV+ L+ LL+
Sbjct: 157 AVVDGGAIPAFISLLAS-PHAHISEQAVWALGNIAGDGSVFRDLVIKYGAVDPLLALLA 214
Score = 35.1 bits (77), Expect = 0.19
Identities = 22/68 (32%), Positives = 33/68 (48%), Gaps = 1/68 (1%)
Frame = +1
Query: 385 IDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSS-GQTRIVVDYGAVNVLVGL 561
I V+ G+VP + L+ T Q EA WA+TN SG + Q +V G + L+ L
Sbjct: 370 IQQVVNHGLVPFLVSVLSKADFKT-QKEAVWAVTNYTSGGTVEQIVYLVHCGIIEPLMNL 428
Query: 562 LSGSTENV 585
L+ +
Sbjct: 429 LTAKDTKI 436
>BC067848-1|AAH67848.1| 529|Homo sapiens karyopherin alpha 2 (RAG
cohort 1, importin alpha 1) protein.
Length = 529
Score = 155 bits (377), Expect = 9e-38
Identities = 78/172 (45%), Positives = 108/172 (62%)
Frame = +1
Query: 94 HRYKNVGLSADELRRRREEEGVQLRKQKREQQLFKRRNVNLPGTNAAGAASQEDINISPS 273
HR+KN G + E+RRRR E V+LRK K++ Q+ KRRNV+ +A + N
Sbjct: 15 HRFKNKGKDSTEMRRRRIEVNVELRKAKKDDQMLKRRNVSSFPDDATSPLQENRNNQGTV 74
Query: 274 DCITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQSGIVPKFIEFLTNHKNP 453
+ D+V + N E Q+ ATQ RKLLS+E PPID +I++G++PKF+ FL
Sbjct: 75 NWSVDDIVKGINSSNVENQLQATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGRTDCS 134
Query: 454 TLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWAL 609
+QFE+AWALTNIASG+S QT+ VVD GA+ + LL+ ++ EQ VWAL
Sbjct: 135 PIQFESAWALTNIASGTSEQTKAVVDGGAIRAFISLLASPHAHISEQDVWAL 186
Score = 59.7 bits (138), Expect = 8e-09
Identities = 35/111 (31%), Positives = 63/111 (56%), Gaps = 1/111 (0%)
Frame = +1
Query: 280 ITPDMVLAVYLDNPEEQVIATQKFR-KLLSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPT 456
I P +V ++ D+PE V+A + L+ PN I V+++G+VP+ ++ L + P
Sbjct: 252 ILPTLVRLLHHDDPE--VLADTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGASELPI 309
Query: 457 LQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWAL 609
+ A A+ NI +G+ QT++V+D GA+ V LL+ N+ ++A W +
Sbjct: 310 VT-PALRAIGNIVTGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWTM 359
Score = 46.4 bits (105), Expect = 8e-05
Identities = 28/82 (34%), Positives = 44/82 (53%)
Frame = +1
Query: 364 SKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAV 543
+K P PPIDAV Q I+P + L +H +P + + WA++ + G + + +VV G V
Sbjct: 239 NKNPAPPIDAVEQ--ILPTLVRLL-HHDDPEVLADTCWAISYLTDGPNERIGMVVKTGVV 295
Query: 544 NVLVGLLSGSTENVCEQAVWAL 609
LV LL S + A+ A+
Sbjct: 296 PQLVKLLGASELPIVTPALRAI 317
Score = 37.5 bits (83), Expect = 0.037
Identities = 21/59 (35%), Positives = 32/59 (54%)
Frame = +1
Query: 391 AVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLS 567
AV+ G + FI L + + + + WAL NIA S +V+ YGAV+ L+ LL+
Sbjct: 157 AVVDGGAIRAFISLLAS-PHAHISEQDVWALGNIAGDGSVFRDLVIKYGAVDPLLALLA 214
Score = 35.1 bits (77), Expect = 0.19
Identities = 22/68 (32%), Positives = 33/68 (48%), Gaps = 1/68 (1%)
Frame = +1
Query: 385 IDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSS-GQTRIVVDYGAVNVLVGL 561
I V+ G+VP + L+ T Q EA WA+TN SG + Q +V G + L+ L
Sbjct: 370 IQQVVNHGLVPFLVSVLSKADFKT-QKEAVWAVTNYTSGGTVEQIVYLVHCGIIEPLMNL 428
Query: 562 LSGSTENV 585
L+ +
Sbjct: 429 LTAKDTKI 436
>D89618-1|BAA20378.1| 521|Homo sapiens karyopherin alhph 3 protein.
Length = 521
Score = 145 bits (351), Expect = 1e-34
Identities = 79/170 (46%), Positives = 104/170 (61%)
Frame = +1
Query: 100 YKNVGLSADELRRRREEEGVQLRKQKREQQLFKRRNVNLPGTNAAGAASQEDINISPSDC 279
+KN G + +RR R E V+LRK KR++ L K+RNV P + S D + +
Sbjct: 15 FKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNV--PQEESL-EDSDVDADFKAQNV 71
Query: 280 ITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTL 459
++ DNP Q+ A Q RKLLS + NPPID +I+SGI+P ++ L NP+L
Sbjct: 72 TLEAILQNATSDNPVVQLSAVQAARKLLSSDQNPPIDDLIKSGILPILVKCLERDDNPSL 131
Query: 460 QFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWAL 609
QFEAAWALTNIASG+S QT+ VV AV + + LL +NVCEQAVWAL
Sbjct: 132 QFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWAL 181
Score = 49.6 bits (113), Expect = 8e-06
Identities = 28/78 (35%), Positives = 45/78 (57%)
Frame = +1
Query: 376 NPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLV 555
N I VI SG+VP F+ L +H+ +Q A A+ NI +G+ QT++V++ ++
Sbjct: 274 NEQIQMVIDSGVVP-FLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFP 332
Query: 556 GLLSGSTENVCEQAVWAL 609
LLS E + ++AVW L
Sbjct: 333 NLLSHPKEKINKEAVWFL 350
Score = 41.5 bits (93), Expect = 0.002
Identities = 26/82 (31%), Positives = 43/82 (52%)
Frame = +1
Query: 364 SKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAV 543
+K+P PP++ V + I+P L H + + + WAL+ + G + Q ++V+D G V
Sbjct: 230 NKDPPPPMETVQE--ILPALC-VLIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVV 286
Query: 544 NVLVGLLSGSTENVCEQAVWAL 609
LV LLS V A+ A+
Sbjct: 287 PFLVPLLSHQEVKVQTAALRAV 308
Score = 40.7 bits (91), Expect = 0.004
Identities = 17/59 (28%), Positives = 32/59 (54%)
Frame = +1
Query: 433 LTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWAL 609
L +H + EA W L+NI +G+ Q + V+D G + +++ L+ ++A WA+
Sbjct: 334 LLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAI 392
Score = 36.7 bits (81), Expect = 0.064
Identities = 23/70 (32%), Positives = 33/70 (47%), Gaps = 1/70 (1%)
Frame = +1
Query: 385 IDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIA-SGSSGQTRIVVDYGAVNVLVGL 561
+ AVI +G++P I L T Q EAAWA++N+ SG Q +V + L
Sbjct: 361 VQAVIDAGLIPMIIHQLAKGDFGT-QKEAAWAISNLTISGRKDQVEYLVQQNVIPPFCNL 419
Query: 562 LSGSTENVCE 591
LS V +
Sbjct: 420 LSVKDSQVVQ 429
>BC024202-1|AAH24202.1| 521|Homo sapiens karyopherin alpha 3
(importin alpha 4) protein.
Length = 521
Score = 144 bits (350), Expect = 2e-34
Identities = 79/170 (46%), Positives = 104/170 (61%)
Frame = +1
Query: 100 YKNVGLSADELRRRREEEGVQLRKQKREQQLFKRRNVNLPGTNAAGAASQEDINISPSDC 279
+KN G + +RR R E V+LRK KR++ L K+RNV P + S D + +
Sbjct: 15 FKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNV--PQEESL-EDSDVDADFKAQNV 71
Query: 280 ITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTL 459
++ DNP Q+ A Q RKLLS + NPPID +I+SGI+P ++ L NP+L
Sbjct: 72 TLEAILQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNPSL 131
Query: 460 QFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWAL 609
QFEAAWALTNIASG+S QT+ VV AV + + LL +NVCEQAVWAL
Sbjct: 132 QFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWAL 181
Score = 49.6 bits (113), Expect = 8e-06
Identities = 28/78 (35%), Positives = 45/78 (57%)
Frame = +1
Query: 376 NPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLV 555
N I VI SG+VP F+ L +H+ +Q A A+ NI +G+ QT++V++ ++
Sbjct: 274 NEQIQMVIDSGVVP-FLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFP 332
Query: 556 GLLSGSTENVCEQAVWAL 609
LLS E + ++AVW L
Sbjct: 333 NLLSHPKEKINKEAVWFL 350
Score = 41.5 bits (93), Expect = 0.002
Identities = 26/82 (31%), Positives = 43/82 (52%)
Frame = +1
Query: 364 SKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAV 543
+K+P PP++ V + I+P L H + + + WAL+ + G + Q ++V+D G V
Sbjct: 230 NKDPPPPMETVQE--ILPALC-VLIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVV 286
Query: 544 NVLVGLLSGSTENVCEQAVWAL 609
LV LLS V A+ A+
Sbjct: 287 PFLVPLLSHQEVKVQTAALRAV 308
Score = 40.7 bits (91), Expect = 0.004
Identities = 17/59 (28%), Positives = 32/59 (54%)
Frame = +1
Query: 433 LTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWAL 609
L +H + EA W L+NI +G+ Q + V+D G + +++ L+ ++A WA+
Sbjct: 334 LLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAI 392
Score = 36.7 bits (81), Expect = 0.064
Identities = 23/70 (32%), Positives = 33/70 (47%), Gaps = 1/70 (1%)
Frame = +1
Query: 385 IDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIA-SGSSGQTRIVVDYGAVNVLVGL 561
+ AVI +G++P I L T Q EAAWA++N+ SG Q +V + L
Sbjct: 361 VQAVIDAGLIPMIIHQLAKGDFGT-QKEAAWAISNLTISGRKDQVEYLVQQNVIPPFCNL 419
Query: 562 LSGSTENVCE 591
LS V +
Sbjct: 420 LSVKDSQVVQ 429
>BC017355-1|AAH17355.1| 521|Homo sapiens karyopherin alpha 3
(importin alpha 4) protein.
Length = 521
Score = 144 bits (350), Expect = 2e-34
Identities = 79/170 (46%), Positives = 104/170 (61%)
Frame = +1
Query: 100 YKNVGLSADELRRRREEEGVQLRKQKREQQLFKRRNVNLPGTNAAGAASQEDINISPSDC 279
+KN G + +RR R E V+LRK KR++ L K+RNV P + S D + +
Sbjct: 15 FKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNV--PQEESL-EDSDVDADFKAQNV 71
Query: 280 ITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTL 459
++ DNP Q+ A Q RKLLS + NPPID +I+SGI+P ++ L NP+L
Sbjct: 72 TLEAILQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNPSL 131
Query: 460 QFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWAL 609
QFEAAWALTNIASG+S QT+ VV AV + + LL +NVCEQAVWAL
Sbjct: 132 QFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWAL 181
Score = 49.6 bits (113), Expect = 8e-06
Identities = 28/78 (35%), Positives = 45/78 (57%)
Frame = +1
Query: 376 NPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLV 555
N I VI SG+VP F+ L +H+ +Q A A+ NI +G+ QT++V++ ++
Sbjct: 274 NEQIQMVIDSGVVP-FLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFP 332
Query: 556 GLLSGSTENVCEQAVWAL 609
LLS E + ++AVW L
Sbjct: 333 NLLSHPKEKINKEAVWFL 350
Score = 41.5 bits (93), Expect = 0.002
Identities = 26/82 (31%), Positives = 43/82 (52%)
Frame = +1
Query: 364 SKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAV 543
+K+P PP++ V + I+P L H + + + WAL+ + G + Q ++V+D G V
Sbjct: 230 NKDPPPPMETVQE--ILPALC-VLIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVV 286
Query: 544 NVLVGLLSGSTENVCEQAVWAL 609
LV LLS V A+ A+
Sbjct: 287 PFLVPLLSHQEVKVQTAALRAV 308
Score = 40.7 bits (91), Expect = 0.004
Identities = 17/59 (28%), Positives = 32/59 (54%)
Frame = +1
Query: 433 LTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWAL 609
L +H + EA W L+NI +G+ Q + V+D G + +++ L+ ++A WA+
Sbjct: 334 LLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAI 392
Score = 36.7 bits (81), Expect = 0.064
Identities = 23/70 (32%), Positives = 33/70 (47%), Gaps = 1/70 (1%)
Frame = +1
Query: 385 IDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIA-SGSSGQTRIVVDYGAVNVLVGL 561
+ AVI +G++P I L T Q EAAWA++N+ SG Q +V + L
Sbjct: 361 VQAVIDAGLIPMIIHQLAKGDFGT-QKEAAWAISNLTISGRKDQVEYLVQQNVIPPFCNL 419
Query: 562 LSGSTENVCE 591
LS V +
Sbjct: 420 LSVKDSQVVQ 429
>AL136301-1|CAH71145.1| 521|Homo sapiens karyopherin alpha 3
(importin alpha 4) protein.
Length = 521
Score = 144 bits (350), Expect = 2e-34
Identities = 79/170 (46%), Positives = 104/170 (61%)
Frame = +1
Query: 100 YKNVGLSADELRRRREEEGVQLRKQKREQQLFKRRNVNLPGTNAAGAASQEDINISPSDC 279
+KN G + +RR R E V+LRK KR++ L K+RNV P + S D + +
Sbjct: 15 FKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNV--PQEESL-EDSDVDADFKAQNV 71
Query: 280 ITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTL 459
++ DNP Q+ A Q RKLLS + NPPID +I+SGI+P ++ L NP+L
Sbjct: 72 TLEAILQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNPSL 131
Query: 460 QFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWAL 609
QFEAAWALTNIASG+S QT+ VV AV + + LL +NVCEQAVWAL
Sbjct: 132 QFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWAL 181
Score = 49.6 bits (113), Expect = 8e-06
Identities = 28/78 (35%), Positives = 45/78 (57%)
Frame = +1
Query: 376 NPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLV 555
N I VI SG+VP F+ L +H+ +Q A A+ NI +G+ QT++V++ ++
Sbjct: 274 NEQIQMVIDSGVVP-FLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFP 332
Query: 556 GLLSGSTENVCEQAVWAL 609
LLS E + ++AVW L
Sbjct: 333 NLLSHPKEKINKEAVWFL 350
Score = 41.5 bits (93), Expect = 0.002
Identities = 26/82 (31%), Positives = 43/82 (52%)
Frame = +1
Query: 364 SKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAV 543
+K+P PP++ V + I+P L H + + + WAL+ + G + Q ++V+D G V
Sbjct: 230 NKDPPPPMETVQE--ILPALC-VLIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVV 286
Query: 544 NVLVGLLSGSTENVCEQAVWAL 609
LV LLS V A+ A+
Sbjct: 287 PFLVPLLSHQEVKVQTAALRAV 308
Score = 40.7 bits (91), Expect = 0.004
Identities = 17/59 (28%), Positives = 32/59 (54%)
Frame = +1
Query: 433 LTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWAL 609
L +H + EA W L+NI +G+ Q + V+D G + +++ L+ ++A WA+
Sbjct: 334 LLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAI 392
Score = 36.7 bits (81), Expect = 0.064
Identities = 23/70 (32%), Positives = 33/70 (47%), Gaps = 1/70 (1%)
Frame = +1
Query: 385 IDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIA-SGSSGQTRIVVDYGAVNVLVGL 561
+ AVI +G++P I L T Q EAAWA++N+ SG Q +V + L
Sbjct: 361 VQAVIDAGLIPMIIHQLAKGDFGT-QKEAAWAISNLTISGRKDQVEYLVQQNVIPPFCNL 419
Query: 562 LSGSTENVCE 591
LS V +
Sbjct: 420 LSVKDSQVVQ 429
>AL135901-3|CAI40716.1| 521|Homo sapiens karyopherin alpha 3
(importin alpha 4) protein.
Length = 521
Score = 144 bits (350), Expect = 2e-34
Identities = 79/170 (46%), Positives = 104/170 (61%)
Frame = +1
Query: 100 YKNVGLSADELRRRREEEGVQLRKQKREQQLFKRRNVNLPGTNAAGAASQEDINISPSDC 279
+KN G + +RR R E V+LRK KR++ L K+RNV P + S D + +
Sbjct: 15 FKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNV--PQEESL-EDSDVDADFKAQNV 71
Query: 280 ITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTL 459
++ DNP Q+ A Q RKLLS + NPPID +I+SGI+P ++ L NP+L
Sbjct: 72 TLEAILQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNPSL 131
Query: 460 QFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWAL 609
QFEAAWALTNIASG+S QT+ VV AV + + LL +NVCEQAVWAL
Sbjct: 132 QFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWAL 181
Score = 49.6 bits (113), Expect = 8e-06
Identities = 28/78 (35%), Positives = 45/78 (57%)
Frame = +1
Query: 376 NPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLV 555
N I VI SG+VP F+ L +H+ +Q A A+ NI +G+ QT++V++ ++
Sbjct: 274 NEQIQMVIDSGVVP-FLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFP 332
Query: 556 GLLSGSTENVCEQAVWAL 609
LLS E + ++AVW L
Sbjct: 333 NLLSHPKEKINKEAVWFL 350
Score = 41.5 bits (93), Expect = 0.002
Identities = 26/82 (31%), Positives = 43/82 (52%)
Frame = +1
Query: 364 SKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAV 543
+K+P PP++ V + I+P L H + + + WAL+ + G + Q ++V+D G V
Sbjct: 230 NKDPPPPMETVQE--ILPALC-VLIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVV 286
Query: 544 NVLVGLLSGSTENVCEQAVWAL 609
LV LLS V A+ A+
Sbjct: 287 PFLVPLLSHQEVKVQTAALRAV 308
Score = 40.7 bits (91), Expect = 0.004
Identities = 17/59 (28%), Positives = 32/59 (54%)
Frame = +1
Query: 433 LTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWAL 609
L +H + EA W L+NI +G+ Q + V+D G + +++ L+ ++A WA+
Sbjct: 334 LLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAI 392
Score = 36.7 bits (81), Expect = 0.064
Identities = 23/70 (32%), Positives = 33/70 (47%), Gaps = 1/70 (1%)
Frame = +1
Query: 385 IDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIA-SGSSGQTRIVVDYGAVNVLVGL 561
+ AVI +G++P I L T Q EAAWA++N+ SG Q +V + L
Sbjct: 361 VQAVIDAGLIPMIIHQLAKGDFGT-QKEAAWAISNLTISGRKDQVEYLVQQNVIPPFCNL 419
Query: 562 LSGSTENVCE 591
LS V +
Sbjct: 420 LSVKDSQVVQ 429
>AK223480-1|BAD97200.1| 521|Homo sapiens karyopherin alpha 3
variant protein.
Length = 521
Score = 144 bits (350), Expect = 2e-34
Identities = 79/170 (46%), Positives = 104/170 (61%)
Frame = +1
Query: 100 YKNVGLSADELRRRREEEGVQLRKQKREQQLFKRRNVNLPGTNAAGAASQEDINISPSDC 279
+KN G + +RR R E V+LRK KR++ L K+RNV P + S D + +
Sbjct: 15 FKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNV--PQEKSL-EDSDVDADFKAQNV 71
Query: 280 ITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTL 459
++ DNP Q+ A Q RKLLS + NPPID +I+SGI+P ++ L NP+L
Sbjct: 72 TLEAILQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNPSL 131
Query: 460 QFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWAL 609
QFEAAWALTNIASG+S QT+ VV AV + + LL +NVCEQAVWAL
Sbjct: 132 QFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWAL 181
Score = 49.6 bits (113), Expect = 8e-06
Identities = 28/78 (35%), Positives = 45/78 (57%)
Frame = +1
Query: 376 NPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLV 555
N I VI SG+VP F+ L +H+ +Q A A+ NI +G+ QT++V++ ++
Sbjct: 274 NEQIQMVIDSGVVP-FLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFP 332
Query: 556 GLLSGSTENVCEQAVWAL 609
LLS E + ++AVW L
Sbjct: 333 NLLSHPKEKINKEAVWFL 350
Score = 41.5 bits (93), Expect = 0.002
Identities = 26/82 (31%), Positives = 43/82 (52%)
Frame = +1
Query: 364 SKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAV 543
+K+P PP++ V + I+P L H + + + WAL+ + G + Q ++V+D G V
Sbjct: 230 NKDPPPPMETVQE--ILPALC-VLIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVV 286
Query: 544 NVLVGLLSGSTENVCEQAVWAL 609
LV LLS V A+ A+
Sbjct: 287 PFLVPLLSHQEVKVQTAALRAV 308
Score = 35.1 bits (77), Expect = 0.19
Identities = 16/59 (27%), Positives = 31/59 (52%)
Frame = +1
Query: 433 LTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWAL 609
L +H + EA W L+NI +G+ Q + V+D G + +++ L+ ++A A+
Sbjct: 334 LLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAARAI 392
>AF005263-1|AAQ13404.1| 521|Homo sapiens importin alpha-3 subunit
protein.
Length = 521
Score = 144 bits (350), Expect = 2e-34
Identities = 79/170 (46%), Positives = 104/170 (61%)
Frame = +1
Query: 100 YKNVGLSADELRRRREEEGVQLRKQKREQQLFKRRNVNLPGTNAAGAASQEDINISPSDC 279
+KN G + +RR R E V+LRK KR++ L K+RNV P + S D + +
Sbjct: 15 FKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNV--PQEESL-EDSDVDADFKAQNV 71
Query: 280 ITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTL 459
++ DNP Q+ A Q RKLLS + NPPID +I+SGI+P ++ L NP+L
Sbjct: 72 TLEAILQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNPSL 131
Query: 460 QFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWAL 609
QFEAAWALTNIASG+S QT+ VV AV + + LL +NVCEQAVWAL
Sbjct: 132 QFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWAL 181
Score = 49.6 bits (113), Expect = 8e-06
Identities = 28/78 (35%), Positives = 45/78 (57%)
Frame = +1
Query: 376 NPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLV 555
N I VI SG+VP F+ L +H+ +Q A A+ NI +G+ QT++V++ ++
Sbjct: 274 NEQIQMVIDSGVVP-FLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFP 332
Query: 556 GLLSGSTENVCEQAVWAL 609
LLS E + ++AVW L
Sbjct: 333 NLLSHPKEKINKEAVWFL 350
Score = 41.5 bits (93), Expect = 0.002
Identities = 26/82 (31%), Positives = 43/82 (52%)
Frame = +1
Query: 364 SKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAV 543
+K+P PP++ V + I+P L H + + + WAL+ + G + Q ++V+D G V
Sbjct: 230 NKDPPPPMETVQE--ILPALC-VLIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVV 286
Query: 544 NVLVGLLSGSTENVCEQAVWAL 609
LV LLS V A+ A+
Sbjct: 287 PFLVPLLSHQEVKVQTAALRAV 308
Score = 40.7 bits (91), Expect = 0.004
Identities = 17/59 (28%), Positives = 32/59 (54%)
Frame = +1
Query: 433 LTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWAL 609
L +H + EA W L+NI +G+ Q + V+D G + +++ L+ ++A WA+
Sbjct: 334 LLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAI 392
Score = 36.7 bits (81), Expect = 0.064
Identities = 23/70 (32%), Positives = 33/70 (47%), Gaps = 1/70 (1%)
Frame = +1
Query: 385 IDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIA-SGSSGQTRIVVDYGAVNVLVGL 561
+ AVI +G++P I L T Q EAAWA++N+ SG Q +V + L
Sbjct: 361 VQAVIDAGLIPMIIHQLAKGDFGT-QKEAAWAISNLTISGRKDQVEYLVQQNVIPPFCNL 419
Query: 562 LSGSTENVCE 591
LS V +
Sbjct: 420 LSVKDSQVVQ 429
>Y12394-1|CAA73026.1| 521|Homo sapiens SRP1-like protein protein.
Length = 521
Score = 143 bits (347), Expect = 4e-34
Identities = 78/170 (45%), Positives = 104/170 (61%)
Frame = +1
Query: 100 YKNVGLSADELRRRREEEGVQLRKQKREQQLFKRRNVNLPGTNAAGAASQEDINISPSDC 279
+KN G + +RR R E ++LRK KR++ L K+RNV P + S D + +
Sbjct: 15 FKNKGRDVETMRRHRNEVTMELRKNKRDEHLLKKRNV--PQEESL-EDSDVDADFKAQNV 71
Query: 280 ITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTL 459
++ DNP Q+ A Q RKLLS + NPPID +I+SGI+P ++ L NP+L
Sbjct: 72 TLEAILQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNPSL 131
Query: 460 QFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWAL 609
QFEAAWALTNIASG+S QT+ VV AV + + LL +NVCEQAVWAL
Sbjct: 132 QFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWAL 181
Score = 50.0 bits (114), Expect = 6e-06
Identities = 34/110 (30%), Positives = 56/110 (50%)
Frame = +1
Query: 280 ITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTL 459
I P + + +Y V+ T L+ N I VI SG+VP F+ L +H+ +
Sbjct: 243 ILPALCVLIY-HTDVNIVVDTVWALSYLTDGGNEQIQMVIDSGVVP-FLVPLLSHQEVKV 300
Query: 460 QFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWAL 609
Q A A+ NI +G+ QT++V++ ++ LLS E + ++AVW L
Sbjct: 301 QTAALRAVGNIVTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFL 350
Score = 40.7 bits (91), Expect = 0.004
Identities = 17/59 (28%), Positives = 32/59 (54%)
Frame = +1
Query: 433 LTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWAL 609
L +H + EA W L+NI +G+ Q + V+D G + +++ L+ ++A WA+
Sbjct: 334 LLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAI 392
Score = 36.7 bits (81), Expect = 0.064
Identities = 23/70 (32%), Positives = 33/70 (47%), Gaps = 1/70 (1%)
Frame = +1
Query: 385 IDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIA-SGSSGQTRIVVDYGAVNVLVGL 561
+ AVI +G++P I L T Q EAAWA++N+ SG Q +V + L
Sbjct: 361 VQAVIDAGLIPMIIHQLAKGDFGT-QKEAAWAISNLTISGRKDQVEYLVQQNVIPPFCNL 419
Query: 562 LSGSTENVCE 591
LS V +
Sbjct: 420 LSVKDSQVVQ 429
>BC035090-1|AAH35090.1| 521|Homo sapiens karyopherin alpha 3
(importin alpha 4) protein.
Length = 521
Score = 143 bits (347), Expect = 4e-34
Identities = 78/170 (45%), Positives = 104/170 (61%)
Frame = +1
Query: 100 YKNVGLSADELRRRREEEGVQLRKQKREQQLFKRRNVNLPGTNAAGAASQEDINISPSDC 279
+KN G + +RR R E V+LRK KR++ L K+RNV P + S D + +
Sbjct: 15 FKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNV--PQEESL-EDSDVDADFKAQNV 71
Query: 280 ITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTL 459
++ DNP Q+ A Q RKLLS + NPPID +I+SGI+P ++ L NP+L
Sbjct: 72 TLEAILQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNPSL 131
Query: 460 QFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWAL 609
QFEAAWALTNIASG+S QT+ +V AV + + LL +NVCEQAVWAL
Sbjct: 132 QFEAAWALTNIASGTSAQTQDIVQSNAVPLFLRLLRSPHQNVCEQAVWAL 181
Score = 49.6 bits (113), Expect = 8e-06
Identities = 28/78 (35%), Positives = 45/78 (57%)
Frame = +1
Query: 376 NPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLV 555
N I VI SG+VP F+ L +H+ +Q A A+ NI +G+ QT++V++ ++
Sbjct: 274 NEQIQMVIDSGVVP-FLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFQ 332
Query: 556 GLLSGSTENVCEQAVWAL 609
LLS E + ++AVW L
Sbjct: 333 NLLSHPKEKINKEAVWFL 350
Score = 41.5 bits (93), Expect = 0.002
Identities = 26/82 (31%), Positives = 43/82 (52%)
Frame = +1
Query: 364 SKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAV 543
+K+P PP++ V + I+P L H + + + WAL+ + G + Q ++V+D G V
Sbjct: 230 NKDPPPPMETVQE--ILPALC-VLIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVV 286
Query: 544 NVLVGLLSGSTENVCEQAVWAL 609
LV LLS V A+ A+
Sbjct: 287 PFLVPLLSHQEVKVQTAALRAV 308
Score = 40.7 bits (91), Expect = 0.004
Identities = 17/59 (28%), Positives = 32/59 (54%)
Frame = +1
Query: 433 LTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWAL 609
L +H + EA W L+NI +G+ Q + V+D G + +++ L+ ++A WA+
Sbjct: 334 LLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAI 392
Score = 36.3 bits (80), Expect = 0.084
Identities = 23/70 (32%), Positives = 33/70 (47%), Gaps = 1/70 (1%)
Frame = +1
Query: 385 IDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIA-SGSSGQTRIVVDYGAVNVLVGL 561
+ AVI +G++P I L T Q EAAWA++N+ SG Q +V + L
Sbjct: 361 VQAVIDAGLIPMIIHQLAKGDFGT-QKEAAWAISNLTISGRKDQVEYLVQQDVIPPFCNL 419
Query: 562 LSGSTENVCE 591
LS V +
Sbjct: 420 LSVKDSQVVQ 429
>AF034756-1|AAB87693.1| 521|Homo sapiens importin-alpha homolog
protein.
Length = 521
Score = 142 bits (343), Expect = 1e-33
Identities = 78/170 (45%), Positives = 103/170 (60%)
Frame = +1
Query: 100 YKNVGLSADELRRRREEEGVQLRKQKREQQLFKRRNVNLPGTNAAGAASQEDINISPSDC 279
+KN G + +RR R E V+LRK KR++ L K+RNV P + S D + +
Sbjct: 15 FKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNV--PQEESL-EDSDVDADFKAQNV 71
Query: 280 ITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTL 459
++ DNP Q+ A Q RKLLS + NPPID +I+SGI+P ++ L NP+L
Sbjct: 72 TLEAILQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNPSL 131
Query: 460 QFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWAL 609
QFEAAWALTNIASG+S QT+ V AV + + LL +NVCEQAVWAL
Sbjct: 132 QFEAAWALTNIASGTSAQTQAVGQSNAVPLFLRLLRSPHQNVCEQAVWAL 181
Score = 49.6 bits (113), Expect = 8e-06
Identities = 28/78 (35%), Positives = 45/78 (57%)
Frame = +1
Query: 376 NPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLV 555
N I VI SG+VP F+ L +H+ +Q A A+ NI +G+ QT++V++ ++
Sbjct: 274 NEQIQMVIDSGVVP-FLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFP 332
Query: 556 GLLSGSTENVCEQAVWAL 609
LLS E + ++AVW L
Sbjct: 333 NLLSHPKEKINKEAVWFL 350
Score = 40.7 bits (91), Expect = 0.004
Identities = 17/59 (28%), Positives = 32/59 (54%)
Frame = +1
Query: 433 LTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWAL 609
L +H + EA W L+NI +G+ Q + V+D G + +++ L+ ++A WA+
Sbjct: 334 LLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAI 392
Score = 38.3 bits (85), Expect = 0.021
Identities = 25/82 (30%), Positives = 42/82 (51%)
Frame = +1
Query: 364 SKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAV 543
+K+P P ++ V + I+P L H + + + WAL+ + G + Q ++V+D G V
Sbjct: 230 NKDPPPTMETVQE--ILPALC-VLIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVV 286
Query: 544 NVLVGLLSGSTENVCEQAVWAL 609
LV LLS V A+ A+
Sbjct: 287 PFLVPLLSHQEVKVQTAALRAV 308
Score = 36.7 bits (81), Expect = 0.064
Identities = 23/70 (32%), Positives = 33/70 (47%), Gaps = 1/70 (1%)
Frame = +1
Query: 385 IDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIA-SGSSGQTRIVVDYGAVNVLVGL 561
+ AVI +G++P I L T Q EAAWA++N+ SG Q +V + L
Sbjct: 361 VQAVIDAGLIPMIIHQLAKGDFGT-QKEAAWAISNLTISGRKDQVEYLVQQNVIPPFCNL 419
Query: 562 LSGSTENVCE 591
LS V +
Sbjct: 420 LSVKDSQVVQ 429
>U93240-1|AAC25605.1| 521|Homo sapiens importin alpha 3 protein.
Length = 521
Score = 138 bits (335), Expect = 1e-32
Identities = 80/170 (47%), Positives = 103/170 (60%)
Frame = +1
Query: 100 YKNVGLSADELRRRREEEGVQLRKQKREQQLFKRRNVNLPGTNAAGAASQEDINISPSDC 279
+KN G + +RR+R E V+LRK KR++ L KRRNV P + S D + +
Sbjct: 15 FKNKGRDLETMRRQRNEVVVELRKNKRDEHLLKRRNV--PHEDIC-EDSDIDGDYRVQNT 71
Query: 280 ITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTL 459
+V DN Q+ A Q RKLLS + NPPID +I+SGI+P + L NP+L
Sbjct: 72 SLEAIVQNASSDNQGIQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVHCLERDDNPSL 131
Query: 460 QFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWAL 609
QFEAAWALTNIASG+S QT+ VV AV + + LL +NVCEQAVWAL
Sbjct: 132 QFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWAL 181
Score = 41.1 bits (92), Expect = 0.003
Identities = 29/123 (23%), Positives = 52/123 (42%)
Frame = +1
Query: 241 ASQEDINISPSDCITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQSGIVPK 420
A E I + I P +V + + Q A + +++ + V+ +
Sbjct: 272 AGNEQIQMVIDSGIVPHLVPLLSHQEVKVQTAALRAVGNIVTGT-DEQTQVVLNCDALSH 330
Query: 421 FIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAV 600
F LT H + EA W L+NI +G+ Q + V+D V +++ LL ++A
Sbjct: 331 FPALLT-HPKEKINKEAVWFLSNITAGNQQQVQAVIDANLVPMIIHLLDKGDFGTQKEAA 389
Query: 601 WAL 609
WA+
Sbjct: 390 WAI 392
Score = 38.7 bits (86), Expect = 0.016
Identities = 24/81 (29%), Positives = 42/81 (51%)
Frame = +1
Query: 367 KEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVN 546
K+P PP++ + + I+P L +H + + + WAL+ + + Q ++V+D G V
Sbjct: 231 KDPPPPMETIQE--ILPALC-VLIHHTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVP 287
Query: 547 VLVGLLSGSTENVCEQAVWAL 609
LV LLS V A+ A+
Sbjct: 288 HLVPLLSHQEVKVQTAALRAV 308
Score = 33.1 bits (72), Expect = 0.79
Identities = 20/62 (32%), Positives = 30/62 (48%), Gaps = 1/62 (1%)
Frame = +1
Query: 385 IDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIA-SGSSGQTRIVVDYGAVNVLVGL 561
+ AVI + +VP I L T Q EAAWA++N+ SG Q ++ + L
Sbjct: 361 VQAVIDANLVPMIIHLLDKGDFGT-QKEAAWAISNLTISGRKDQVAYLIQQNVIPPFCNL 419
Query: 562 LS 567
L+
Sbjct: 420 LT 421
>BC034493-1|AAH34493.1| 521|Homo sapiens karyopherin alpha 4
(importin alpha 3) protein.
Length = 521
Score = 138 bits (335), Expect = 1e-32
Identities = 80/170 (47%), Positives = 103/170 (60%)
Frame = +1
Query: 100 YKNVGLSADELRRRREEEGVQLRKQKREQQLFKRRNVNLPGTNAAGAASQEDINISPSDC 279
+KN G + +RR+R E V+LRK KR++ L KRRNV P + S D + +
Sbjct: 15 FKNKGRDLETMRRQRNEVVVELRKNKRDEHLLKRRNV--PHEDIC-EDSDIDGDYRVQNT 71
Query: 280 ITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTL 459
+V DN Q+ A Q RKLLS + NPPID +I+SGI+P + L NP+L
Sbjct: 72 SLEAIVQNASSDNQGIQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVHCLERDDNPSL 131
Query: 460 QFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWAL 609
QFEAAWALTNIASG+S QT+ VV AV + + LL +NVCEQAVWAL
Sbjct: 132 QFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWAL 181
Score = 41.1 bits (92), Expect = 0.003
Identities = 29/123 (23%), Positives = 52/123 (42%)
Frame = +1
Query: 241 ASQEDINISPSDCITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQSGIVPK 420
A E I + I P +V + + Q A + +++ + V+ +
Sbjct: 272 AGNEQIQMVIDSGIVPHLVPLLSHQEVKVQTAALRAVGNIVTGT-DEQTQVVLNCDALSH 330
Query: 421 FIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAV 600
F LT H + EA W L+NI +G+ Q + V+D V +++ LL ++A
Sbjct: 331 FPALLT-HPKEKINKEAVWFLSNITAGNQQQVQAVIDANLVPMIIHLLDKGDFGTQKEAA 389
Query: 601 WAL 609
WA+
Sbjct: 390 WAI 392
Score = 38.7 bits (86), Expect = 0.016
Identities = 24/81 (29%), Positives = 42/81 (51%)
Frame = +1
Query: 367 KEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVN 546
K+P PP++ + + I+P L +H + + + WAL+ + + Q ++V+D G V
Sbjct: 231 KDPPPPMETIQE--ILPALC-VLIHHTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVP 287
Query: 547 VLVGLLSGSTENVCEQAVWAL 609
LV LLS V A+ A+
Sbjct: 288 HLVPLLSHQEVKVQTAALRAV 308
Score = 33.1 bits (72), Expect = 0.79
Identities = 20/62 (32%), Positives = 30/62 (48%), Gaps = 1/62 (1%)
Frame = +1
Query: 385 IDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIA-SGSSGQTRIVVDYGAVNVLVGL 561
+ AVI + +VP I L T Q EAAWA++N+ SG Q ++ + L
Sbjct: 361 VQAVIDANLVPMIIHLLDKGDFGT-QKEAAWAISNLTISGRKDQVAYLIQQNVIPPFCNL 419
Query: 562 LS 567
L+
Sbjct: 420 LT 421
>BC028691-1|AAH28691.1| 521|Homo sapiens karyopherin alpha 4
(importin alpha 3) protein.
Length = 521
Score = 138 bits (335), Expect = 1e-32
Identities = 80/170 (47%), Positives = 103/170 (60%)
Frame = +1
Query: 100 YKNVGLSADELRRRREEEGVQLRKQKREQQLFKRRNVNLPGTNAAGAASQEDINISPSDC 279
+KN G + +RR+R E V+LRK KR++ L KRRNV P + S D + +
Sbjct: 15 FKNKGRDLETMRRQRNEVVVELRKNKRDEHLLKRRNV--PHEDIC-EDSDIDGDYRVQNT 71
Query: 280 ITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTL 459
+V DN Q+ A Q RKLLS + NPPID +I+SGI+P + L NP+L
Sbjct: 72 SLEAIVQNASSDNQGIQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVHCLERDDNPSL 131
Query: 460 QFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWAL 609
QFEAAWALTNIASG+S QT+ VV AV + + LL +NVCEQAVWAL
Sbjct: 132 QFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWAL 181
Score = 41.1 bits (92), Expect = 0.003
Identities = 29/123 (23%), Positives = 52/123 (42%)
Frame = +1
Query: 241 ASQEDINISPSDCITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQSGIVPK 420
A E I + I P +V + + Q A + +++ + V+ +
Sbjct: 272 AGNEQIQMVIDSGIVPHLVPLLSHQEVKVQTAALRAVGNIVTGT-DEQTQVVLNCDALSH 330
Query: 421 FIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAV 600
F LT H + EA W L+NI +G+ Q + V+D V +++ LL ++A
Sbjct: 331 FPALLT-HPKEKINKEAVWFLSNITAGNQQQVQAVIDANLVPMIIHLLDKGDFGTQKEAA 389
Query: 601 WAL 609
WA+
Sbjct: 390 WAI 392
Score = 38.7 bits (86), Expect = 0.016
Identities = 24/81 (29%), Positives = 42/81 (51%)
Frame = +1
Query: 367 KEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVN 546
K+P PP++ + + I+P L +H + + + WAL+ + + Q ++V+D G V
Sbjct: 231 KDPPPPMETIQE--ILPALC-VLIHHTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVP 287
Query: 547 VLVGLLSGSTENVCEQAVWAL 609
LV LLS V A+ A+
Sbjct: 288 HLVPLLSHQEVKVQTAALRAV 308
Score = 33.1 bits (72), Expect = 0.79
Identities = 20/62 (32%), Positives = 30/62 (48%), Gaps = 1/62 (1%)
Frame = +1
Query: 385 IDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIA-SGSSGQTRIVVDYGAVNVLVGL 561
+ AVI + +VP I L T Q EAAWA++N+ SG Q ++ + L
Sbjct: 361 VQAVIDANLVPMIIHLLDKGDFGT-QKEAAWAISNLTISGRKDQVAYLIQQNVIPPFCNL 419
Query: 562 LS 567
L+
Sbjct: 420 LT 421
>AB002533-1|BAA19546.1| 521|Homo sapiens Qip1 protein.
Length = 521
Score = 138 bits (335), Expect = 1e-32
Identities = 80/170 (47%), Positives = 103/170 (60%)
Frame = +1
Query: 100 YKNVGLSADELRRRREEEGVQLRKQKREQQLFKRRNVNLPGTNAAGAASQEDINISPSDC 279
+KN G + +RR+R E V+LRK KR++ L KRRNV P + S D + +
Sbjct: 15 FKNKGRDLETMRRQRNEVVVELRKNKRDEHLLKRRNV--PHEDIC-EDSDIDGDYRVQNT 71
Query: 280 ITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTL 459
+V DN Q+ A Q RKLLS + NPPID +I+SGI+P + L NP+L
Sbjct: 72 SLEAIVQNASSDNQGIQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVHCLERDDNPSL 131
Query: 460 QFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWAL 609
QFEAAWALTNIASG+S QT+ VV AV + + LL +NVCEQAVWAL
Sbjct: 132 QFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWAL 181
Score = 41.1 bits (92), Expect = 0.003
Identities = 29/123 (23%), Positives = 52/123 (42%)
Frame = +1
Query: 241 ASQEDINISPSDCITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQSGIVPK 420
A E I + I P +V + + Q A + +++ + V+ +
Sbjct: 272 AGNEQIQMVIDSGIVPHLVPLLSHQEVKVQTAALRAVGNIVTGT-DEQTQVVLNCDALSH 330
Query: 421 FIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAV 600
F LT H + EA W L+NI +G+ Q + V+D V +++ LL ++A
Sbjct: 331 FPALLT-HPKEKINKEAVWFLSNITAGNQQQVQAVIDANLVPMIIHLLDKGDFGTQKEAA 389
Query: 601 WAL 609
WA+
Sbjct: 390 WAI 392
Score = 38.7 bits (86), Expect = 0.016
Identities = 24/81 (29%), Positives = 42/81 (51%)
Frame = +1
Query: 367 KEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVN 546
K+P PP++ + + I+P L +H + + + WAL+ + + Q ++V+D G V
Sbjct: 231 KDPPPPMETIQE--ILPALC-VLIHHTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVP 287
Query: 547 VLVGLLSGSTENVCEQAVWAL 609
LV LLS V A+ A+
Sbjct: 288 HLVPLLSHQEVKVQTAALRAV 308
Score = 33.1 bits (72), Expect = 0.79
Identities = 20/62 (32%), Positives = 30/62 (48%), Gaps = 1/62 (1%)
Frame = +1
Query: 385 IDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIA-SGSSGQTRIVVDYGAVNVLVGL 561
+ AVI + +VP I L T Q EAAWA++N+ SG Q ++ + L
Sbjct: 361 VQAVIDANLVPMIIHLLDKGDFGT-QKEAAWAISNLTISGRKDQVAYLIQQNVIPPFCNL 419
Query: 562 LS 567
L+
Sbjct: 420 LT 421
>AL132795-6|CAI20501.1| 142|Homo sapiens karyopherin alpha 5
(importin alpha 6) protein.
Length = 142
Score = 135 bits (326), Expect = 1e-31
Identities = 71/129 (55%), Positives = 94/129 (72%), Gaps = 8/129 (6%)
Frame = +1
Query: 100 YKNVGLSADELRRRREEEGVQLRKQKREQQLFKRRNVNLPGTNAAGAASQ-EDINISPS- 273
YKN L+ E+RRRREEEG+QLRKQKRE+QLFKRRNV LP + + S +D +IS +
Sbjct: 14 YKNKALNPQEMRRRREEEGIQLRKQKREEQLFKRRNVYLPRNDESMLESPIQDPDISSTV 73
Query: 274 -----DCITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQS-GIVPKFIEFL 435
+ +T DMV ++ +N ++Q+ ATQKFRKLLSKEPNPPID VIQ G+V +F++FL
Sbjct: 74 PIPEEEVVTTDMVQMIFSNNADQQLTATQKFRKLLSKEPNPPIDQVIQKPGVVQRFVKFL 133
Query: 436 TNHKNPTLQ 462
++N TLQ
Sbjct: 134 ERNENCTLQ 142
>AL049795-1|CAI22054.1| 321|Homo sapiens karyopherin alpha 6
(importin alpha 7) protein.
Length = 321
Score = 93.1 bits (221), Expect = 7e-19
Identities = 64/143 (44%), Positives = 85/143 (59%), Gaps = 6/143 (4%)
Frame = +1
Query: 199 RRNVNLPGTNAAGAASQ-EDINISPS---DCITPDMVLAVYLDNPEEQVIATQKFRKLLS 366
RRNV L AA S D +S + IT +MV ++ D+ + Q+ TQKFRKLLS
Sbjct: 1 RRNVELINEEAAMFDSLLMDSYVSSTTGESVITREMVEMLFSDDSDLQLATTQKFRKLLS 60
Query: 367 KEPNPPIDAVIQS-GIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAV 543
KEP+PPID VI + +V +F+EFL ++N TLQ A WAL NIA SS V++ +
Sbjct: 61 KEPSPPIDEVINTPRVVDRFVEFLKRNENCTLQ--AVWALGNIAGDSSVCRDYVLNCSIL 118
Query: 544 NVLVGLLSGSTE-NVCEQAVWAL 609
N L+ LL+ ST + AVWAL
Sbjct: 119 NPLLTLLTKSTRLTMTRNAVWAL 141
Score = 52.0 bits (119), Expect = 2e-06
Identities = 28/83 (33%), Positives = 47/83 (56%)
Frame = +1
Query: 361 LSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGA 540
LS PN I AVI SG+ + +E L H + + A A+ NI +G QT+++++ A
Sbjct: 186 LSDGPNEKIQAVIDSGVCRRLVELLM-HNDYKVASPALRAVGNIVTGDDIQTQVILNCSA 244
Query: 541 VNVLVGLLSGSTENVCEQAVWAL 609
+ L+ LLS E++ ++A W +
Sbjct: 245 LPCLLHLLSSPKESIRKEACWTI 267
Score = 40.7 bits (91), Expect = 0.004
Identities = 18/72 (25%), Positives = 39/72 (54%)
Frame = +1
Query: 394 VIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGS 573
++ +P + L++ K +++ EA W ++NI +G+ Q + V+D VL+ +L +
Sbjct: 239 ILNCSALPCLLHLLSSPKE-SIRKEACWTISNITAGNRAQIQAVIDANIFPVLIEILQKA 297
Query: 574 TENVCEQAVWAL 609
++A WA+
Sbjct: 298 EFRTRKEAAWAI 309
Score = 34.3 bits (75), Expect = 0.34
Identities = 19/41 (46%), Positives = 24/41 (58%)
Frame = +1
Query: 385 IDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSS 507
I AVI + I P IE L + T + EAAWA+TN SG +
Sbjct: 278 IQAVIDANIFPVLIEILQKAEFRTRK-EAAWAITNATSGGT 317
Score = 33.9 bits (74), Expect = 0.45
Identities = 23/83 (27%), Positives = 39/83 (46%)
Frame = +1
Query: 361 LSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGA 540
L + NPP + S +P L + + L +A WAL+ ++ G + + + V+D G
Sbjct: 144 LCRGKNPPPEFAKVSPCLPVLSRLLFSSDSDLLA-DACWALSYLSDGPNEKIQAVIDSGV 202
Query: 541 VNVLVGLLSGSTENVCEQAVWAL 609
LV LL + V A+ A+
Sbjct: 203 CRRLVELLMHNDYKVASPALRAV 225
>Y12393-1|CAA73025.1| 281|Homo sapiens SRP1-like protein protein.
Length = 281
Score = 41.1 bits (92), Expect = 0.003
Identities = 29/123 (23%), Positives = 52/123 (42%)
Frame = +1
Query: 241 ASQEDINISPSDCITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQSGIVPK 420
A E I + I P +V + + Q A + +++ + V+ +
Sbjct: 32 AGNEQIQMVIDSGIVPHLVPLLSHQEVKVQTAALRAVGNIVTGT-DEQTQVVLNCDALSH 90
Query: 421 FIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAV 600
F LT H + EA W L+NI +G+ Q + V+D V +++ LL ++A
Sbjct: 91 FPALLT-HPKEKINKEAVWFLSNITAGNQQQVQAVIDANLVPMIIHLLDKGDFGTQKEAA 149
Query: 601 WAL 609
WA+
Sbjct: 150 WAI 152
Score = 33.1 bits (72), Expect = 0.79
Identities = 20/62 (32%), Positives = 30/62 (48%), Gaps = 1/62 (1%)
Frame = +1
Query: 385 IDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIA-SGSSGQTRIVVDYGAVNVLVGL 561
+ AVI + +VP I L T Q EAAWA++N+ SG Q ++ + L
Sbjct: 121 VQAVIDANLVPMIIHLLDKGDFGT-QKEAAWAISNLTISGRKDQVAYLIQQNVIPPFCNL 179
Query: 562 LS 567
L+
Sbjct: 180 LT 181
Score = 32.3 bits (70), Expect = 1.4
Identities = 18/59 (30%), Positives = 30/59 (50%)
Frame = +1
Query: 433 LTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWAL 609
L +H + + + WAL+ + + Q ++V+D G V LV LLS V A+ A+
Sbjct: 10 LIHHTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLLSHQEVKVQTAALRAV 68
>CR533552-1|CAG38583.1| 509|Homo sapiens SPAG6 protein.
Length = 509
Score = 35.9 bits (79), Expect = 0.11
Identities = 23/74 (31%), Positives = 37/74 (50%)
Frame = +1
Query: 388 DAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLS 567
+AV++ I+P+ + L +N + AA+ L + S + +VD GA++ LV L
Sbjct: 77 EAVVKCDILPQLVYSLAE-QNRFYKKAAAFVLRAVGKHSPQLAQAIVDCGALDTLVICLE 135
Query: 568 GSTENVCEQAVWAL 609
V E A WAL
Sbjct: 136 DFDPGVKEAAAWAL 149
Score = 33.1 bits (72), Expect = 0.79
Identities = 20/55 (36%), Positives = 32/55 (58%)
Frame = +1
Query: 391 AVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLV 555
A++ G + + L + +P ++ AAWAL IA ++ +R VVD GAV +LV
Sbjct: 120 AIVDCGALDTLVICLEDF-DPGVKEAAAWALRYIARHNAELSRAVVDAGAVPLLV 173
>BC030585-1|AAH30585.1| 458|Homo sapiens sperm associated antigen 6
protein.
Length = 458
Score = 35.9 bits (79), Expect = 0.11
Identities = 23/74 (31%), Positives = 37/74 (50%)
Frame = +1
Query: 388 DAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLS 567
+AV++ I+P+ + L +N + AA+ L + S + +VD GA++ LV L
Sbjct: 77 EAVVKCDILPQLVYSLAE-QNRFYKKAAAFVLRAVGKHSPQLAQAIVDCGALDTLVICLE 135
Query: 568 GSTENVCEQAVWAL 609
V E A WAL
Sbjct: 136 DFDPGVKEAAAWAL 149
Score = 31.5 bits (68), Expect = 2.4
Identities = 19/55 (34%), Positives = 32/55 (58%)
Frame = +1
Query: 391 AVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLV 555
A++ G + + L + +P ++ AAWAL IA ++ ++ VVD GAV +LV
Sbjct: 120 AIVDCGALDTLVICLEDF-DPGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLV 173
>AL513128-4|CAH72210.1| 509|Homo sapiens sperm associated antigen 6
protein.
Length = 509
Score = 35.9 bits (79), Expect = 0.11
Identities = 23/74 (31%), Positives = 37/74 (50%)
Frame = +1
Query: 388 DAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLS 567
+AV++ I+P+ + L +N + AA+ L + S + +VD GA++ LV L
Sbjct: 77 EAVVKCDILPQLVYSLAE-QNRFYKKAAAFVLRAVGKHSPQLAQAIVDCGALDTLVICLE 135
Query: 568 GSTENVCEQAVWAL 609
V E A WAL
Sbjct: 136 DFDPGVKEAAAWAL 149
Score = 31.5 bits (68), Expect = 2.4
Identities = 19/55 (34%), Positives = 32/55 (58%)
Frame = +1
Query: 391 AVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLV 555
A++ G + + L + +P ++ AAWAL IA ++ ++ VVD GAV +LV
Sbjct: 120 AIVDCGALDTLVICLEDF-DPGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLV 173
>AL513128-3|CAH72209.1| 458|Homo sapiens sperm associated antigen 6
protein.
Length = 458
Score = 35.9 bits (79), Expect = 0.11
Identities = 23/74 (31%), Positives = 37/74 (50%)
Frame = +1
Query: 388 DAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLS 567
+AV++ I+P+ + L +N + AA+ L + S + +VD GA++ LV L
Sbjct: 77 EAVVKCDILPQLVYSLAE-QNRFYKKAAAFVLRAVGKHSPQLAQAIVDCGALDTLVICLE 135
Query: 568 GSTENVCEQAVWAL 609
V E A WAL
Sbjct: 136 DFDPGVKEAAAWAL 149
Score = 31.5 bits (68), Expect = 2.4
Identities = 19/55 (34%), Positives = 32/55 (58%)
Frame = +1
Query: 391 AVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLV 555
A++ G + + L + +P ++ AAWAL IA ++ ++ VVD GAV +LV
Sbjct: 120 AIVDCGALDTLVICLEDF-DPGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLV 173
>AL513128-1|CAH72207.1| 246|Homo sapiens sperm associated antigen 6
protein.
Length = 246
Score = 35.9 bits (79), Expect = 0.11
Identities = 23/74 (31%), Positives = 37/74 (50%)
Frame = +1
Query: 388 DAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLS 567
+AV++ I+P+ + L +N + AA+ L + S + +VD GA++ LV L
Sbjct: 153 EAVVKCDILPQLVYSLAE-QNRFYKKAAAFVLRAVGKHSPQLAQAIVDCGALDTLVICLE 211
Query: 568 GSTENVCEQAVWAL 609
V E A WAL
Sbjct: 212 DFDPGVKEAAAWAL 225
>AL158211-15|CAI15963.1| 509|Homo sapiens sperm associated antigen
6 protein.
Length = 509
Score = 35.9 bits (79), Expect = 0.11
Identities = 23/74 (31%), Positives = 37/74 (50%)
Frame = +1
Query: 388 DAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLS 567
+AV++ I+P+ + L +N + AA+ L + S + +VD GA++ LV L
Sbjct: 77 EAVVKCDILPQLVYSLAE-QNRFYKKAAAFVLRAVGKHSPQLAQAIVDCGALDTLVICLE 135
Query: 568 GSTENVCEQAVWAL 609
V E A WAL
Sbjct: 136 DFDPGVKEAAAWAL 149
Score = 31.5 bits (68), Expect = 2.4
Identities = 19/55 (34%), Positives = 32/55 (58%)
Frame = +1
Query: 391 AVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLV 555
A++ G + + L + +P ++ AAWAL IA ++ ++ VVD GAV +LV
Sbjct: 120 AIVDCGALDTLVICLEDF-DPGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLV 173
>AL158211-14|CAI15962.1| 458|Homo sapiens sperm associated antigen
6 protein.
Length = 458
Score = 35.9 bits (79), Expect = 0.11
Identities = 23/74 (31%), Positives = 37/74 (50%)
Frame = +1
Query: 388 DAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLS 567
+AV++ I+P+ + L +N + AA+ L + S + +VD GA++ LV L
Sbjct: 77 EAVVKCDILPQLVYSLAE-QNRFYKKAAAFVLRAVGKHSPQLAQAIVDCGALDTLVICLE 135
Query: 568 GSTENVCEQAVWAL 609
V E A WAL
Sbjct: 136 DFDPGVKEAAAWAL 149
Score = 31.5 bits (68), Expect = 2.4
Identities = 19/55 (34%), Positives = 32/55 (58%)
Frame = +1
Query: 391 AVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLV 555
A++ G + + L + +P ++ AAWAL IA ++ ++ VVD GAV +LV
Sbjct: 120 AIVDCGALDTLVICLEDF-DPGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLV 173
>AL158211-12|CAI15960.1| 246|Homo sapiens sperm associated antigen
6 protein.
Length = 246
Score = 35.9 bits (79), Expect = 0.11
Identities = 23/74 (31%), Positives = 37/74 (50%)
Frame = +1
Query: 388 DAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLS 567
+AV++ I+P+ + L +N + AA+ L + S + +VD GA++ LV L
Sbjct: 153 EAVVKCDILPQLVYSLAE-QNRFYKKAAAFVLRAVGKHSPQLAQAIVDCGALDTLVICLE 211
Query: 568 GSTENVCEQAVWAL 609
V E A WAL
Sbjct: 212 DFDPGVKEAAAWAL 225
>AK223275-1|BAD96995.1| 1181|Homo sapiens AT rich interactive domain
1A (SWI- like) isoform a variant protein.
Length = 1181
Score = 35.9 bits (79), Expect = 0.11
Identities = 20/51 (39%), Positives = 28/51 (54%), Gaps = 1/51 (1%)
Frame = +1
Query: 424 IEFLTNHKNPTLQFEAAWALTNIASGSSGQTR-IVVDYGAVNVLVGLLSGS 573
+ FL++ KNP + A L N+A G S TR I V G++ L+G L S
Sbjct: 1048 VRFLSDRKNPVCREMAVVLLANLAQGDSLATRAIAVQKGSIGNLLGFLEDS 1098
>AF079363-1|AAC32590.1| 509|Homo sapiens sperm flagellar protein
Repro-SA-1 protein.
Length = 509
Score = 35.9 bits (79), Expect = 0.11
Identities = 23/74 (31%), Positives = 37/74 (50%)
Frame = +1
Query: 388 DAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLS 567
+AV++ I+P+ + L +N + AA+ L + S + +VD GA++ LV L
Sbjct: 77 EAVVKCDILPQLVYSLAE-QNRFYKKAAAFVLRAVGKHSPQLAQAIVDCGALDTLVICLE 135
Query: 568 GSTENVCEQAVWAL 609
V E A WAL
Sbjct: 136 DFDPGVKEAAAWAL 149
Score = 31.5 bits (68), Expect = 2.4
Identities = 19/55 (34%), Positives = 32/55 (58%)
Frame = +1
Query: 391 AVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLV 555
A++ G + + L + +P ++ AAWAL IA ++ ++ VVD GAV +LV
Sbjct: 120 AIVDCGALDTLVICLEDF-DPGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLV 173
>BC041699-1|AAH41699.1| 659|Homo sapiens armadillo repeat
containing 8 protein.
Length = 659
Score = 34.7 bits (76), Expect = 0.26
Identities = 26/98 (26%), Positives = 48/98 (48%), Gaps = 1/98 (1%)
Frame = +1
Query: 295 VLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAA 474
++ V + P+E ++ L E +P + +++SG V + + LT +NP L+
Sbjct: 417 LMKVLQNAPDEILVVASSMLCNLLLEFSPSKEPILESGAV-ELLCGLTQSENPALRVNGI 475
Query: 475 WALTNIASGSSGQTRI-VVDYGAVNVLVGLLSGSTENV 585
WAL N+A + + + ++ + L LLS S NV
Sbjct: 476 WALMNMAFQAEQKIKADILRSLSTEQLFRLLSDSDLNV 513
>BC032661-1|AAH32661.1| 659|Homo sapiens armadillo repeat
containing 8 protein.
Length = 659
Score = 34.7 bits (76), Expect = 0.26
Identities = 26/98 (26%), Positives = 48/98 (48%), Gaps = 1/98 (1%)
Frame = +1
Query: 295 VLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAA 474
++ V + P+E ++ L E +P + +++SG V + + LT +NP L+
Sbjct: 417 LMKVLQNAPDEILVVASSMLCNLLLEFSPSKEPILESGAV-ELLCGLTQSENPALRVNGI 475
Query: 475 WALTNIASGSSGQTRI-VVDYGAVNVLVGLLSGSTENV 585
WAL N+A + + + ++ + L LLS S NV
Sbjct: 476 WALMNMAFQAEQKIKADILRSLSTEQLFRLLSDSDLNV 513
>AK001882-1|BAA91959.1| 431|Homo sapiens protein ( Homo sapiens
cDNA FLJ11020 fis, clone PLACE1003625, weakly similar to
ARMADILLO SEGMENT POLARITY PROTEIN. ).
Length = 431
Score = 34.7 bits (76), Expect = 0.26
Identities = 26/98 (26%), Positives = 48/98 (48%), Gaps = 1/98 (1%)
Frame = +1
Query: 295 VLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAA 474
++ V + P+E ++ L E +P + +++SG V + + LT +NP L+
Sbjct: 189 LMKVLQNAPDEILVVASSMLCNLLLEFSPSKEPILESGAV-ELLCGLTQSENPALRVNGI 247
Query: 475 WALTNIASGSSGQTRI-VVDYGAVNVLVGLLSGSTENV 585
WAL N+A + + + ++ + L LLS S NV
Sbjct: 248 WALMNMAFQAEQKIKADILRSLSTEQLFRLLSDSDLNV 285
>AL096748-1|CAB46423.1| 242|Homo sapiens hypothetical protein
protein.
Length = 242
Score = 34.3 bits (75), Expect = 0.34
Identities = 26/97 (26%), Positives = 47/97 (48%), Gaps = 1/97 (1%)
Frame = +1
Query: 298 LAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAW 477
+ V + P+E ++ L E +P + +++SG V + + LT +NP L+ W
Sbjct: 1 MKVLQNAPDEILVVASSMLCNLLLEFSPSKEPILESGAV-ELLCGLTQSENPALRVNGIW 59
Query: 478 ALTNIASGSSGQTRI-VVDYGAVNVLVGLLSGSTENV 585
AL N+A + + + ++ + L LLS S NV
Sbjct: 60 ALMNMAFQAEQKIKADILRSLSTEQLFRLLSDSDLNV 96
>BC112895-1|AAI12896.1| 164|Homo sapiens ARID1A protein protein.
Length = 164
Score = 33.9 bits (74), Expect = 0.45
Identities = 19/51 (37%), Positives = 27/51 (52%), Gaps = 1/51 (1%)
Frame = +1
Query: 424 IEFLTNHKNPTLQFEAAWALTNIASGSSGQTR-IVVDYGAVNVLVGLLSGS 573
+ FL++ KNP + A L N+A G S R I V G++ L+G L S
Sbjct: 31 VRFLSDRKNPVCREMAVVLLANLAQGDSLAARAIAVQKGSIGNLLGFLEDS 81
>AL512408-3|CAI23484.1| 2285|Homo sapiens AT rich interactive domain
1A (SWI-like) protein.
Length = 2285
Score = 33.9 bits (74), Expect = 0.45
Identities = 19/51 (37%), Positives = 27/51 (52%), Gaps = 1/51 (1%)
Frame = +1
Query: 424 IEFLTNHKNPTLQFEAAWALTNIASGSSGQTR-IVVDYGAVNVLVGLLSGS 573
+ FL++ KNP + A L N+A G S R I V G++ L+G L S
Sbjct: 2152 VRFLSDRKNPVCREMAVVLLANLAQGDSLAARAIAVQKGSIGNLLGFLEDS 2202
>AL512408-1|CAI23482.1| 1685|Homo sapiens AT rich interactive domain
1A (SWI-like) protein.
Length = 1685
Score = 33.9 bits (74), Expect = 0.45
Identities = 19/51 (37%), Positives = 27/51 (52%), Gaps = 1/51 (1%)
Frame = +1
Query: 424 IEFLTNHKNPTLQFEAAWALTNIASGSSGQTR-IVVDYGAVNVLVGLLSGS 573
+ FL++ KNP + A L N+A G S R I V G++ L+G L S
Sbjct: 1552 VRFLSDRKNPVCREMAVVLLANLAQGDSLAARAIAVQKGSIGNLLGFLEDS 1602
>AL034380-9|CAI21623.1| 2285|Homo sapiens AT rich interactive domain
1A (SWI-like) protein.
Length = 2285
Score = 33.9 bits (74), Expect = 0.45
Identities = 19/51 (37%), Positives = 27/51 (52%), Gaps = 1/51 (1%)
Frame = +1
Query: 424 IEFLTNHKNPTLQFEAAWALTNIASGSSGQTR-IVVDYGAVNVLVGLLSGS 573
+ FL++ KNP + A L N+A G S R I V G++ L+G L S
Sbjct: 2152 VRFLSDRKNPVCREMAVVLLANLAQGDSLAARAIAVQKGSIGNLLGFLEDS 2202
>AL034380-6|CAI21621.1| 1685|Homo sapiens AT rich interactive domain
1A (SWI-like) protein.
Length = 1685
Score = 33.9 bits (74), Expect = 0.45
Identities = 19/51 (37%), Positives = 27/51 (52%), Gaps = 1/51 (1%)
Frame = +1
Query: 424 IEFLTNHKNPTLQFEAAWALTNIASGSSGQTR-IVVDYGAVNVLVGLLSGS 573
+ FL++ KNP + A L N+A G S R I V G++ L+G L S
Sbjct: 1552 VRFLSDRKNPVCREMAVVLLANLAQGDSLAARAIAVQKGSIGNLLGFLEDS 1602
>AK074940-1|BAC11306.1| 754|Homo sapiens protein ( Homo sapiens
cDNA FLJ90459 fis, clone NT2RP3001754. ).
Length = 754
Score = 33.9 bits (74), Expect = 0.45
Identities = 19/51 (37%), Positives = 27/51 (52%), Gaps = 1/51 (1%)
Frame = +1
Query: 424 IEFLTNHKNPTLQFEAAWALTNIASGSSGQTR-IVVDYGAVNVLVGLLSGS 573
+ FL++ KNP + A L N+A G S R I V G++ L+G L S
Sbjct: 621 VRFLSDRKNPVCREMAVVLLANLAQGDSLAARAIAVQKGSIGNLLGFLEDS 671
>AK027655-1|BAB55270.1| 613|Homo sapiens protein ( Homo sapiens
cDNA FLJ14749 fis, clone NT2RP3002876, weakly similar to
Drosophila melanogaster eyelid (eld) mRNA. ).
Length = 613
Score = 33.9 bits (74), Expect = 0.45
Identities = 19/51 (37%), Positives = 27/51 (52%), Gaps = 1/51 (1%)
Frame = +1
Query: 424 IEFLTNHKNPTLQFEAAWALTNIASGSSGQTR-IVVDYGAVNVLVGLLSGS 573
+ FL++ KNP + A L N+A G S R I V G++ L+G L S
Sbjct: 480 VRFLSDRKNPVCREMAVVLLANLAQGDSLAARAIAVQKGSIGNLLGFLEDS 530
>AK027467-1|BAB55132.1| 375|Homo sapiens protein ( Homo sapiens
cDNA FLJ14561 fis, clone NT2RM2002091, weakly similar to
Drosophila melanogaster eyelid (eld) mRNA. ).
Length = 375
Score = 33.9 bits (74), Expect = 0.45
Identities = 19/51 (37%), Positives = 27/51 (52%), Gaps = 1/51 (1%)
Frame = +1
Query: 424 IEFLTNHKNPTLQFEAAWALTNIASGSSGQTR-IVVDYGAVNVLVGLLSGS 573
+ FL++ KNP + A L N+A G S R I V G++ L+G L S
Sbjct: 242 VRFLSDRKNPVCREMAVVLLANLAQGDSLAARAIAVQKGSIGNLLGFLEDS 292
>AK027442-1|BAB55114.1| 527|Homo sapiens protein ( Homo sapiens
cDNA FLJ14536 fis, clone NT2RM2001105, weakly similar to
Drosophila melanogaster eyelid (eld) mRNA. ).
Length = 527
Score = 33.9 bits (74), Expect = 0.45
Identities = 19/51 (37%), Positives = 27/51 (52%), Gaps = 1/51 (1%)
Frame = +1
Query: 424 IEFLTNHKNPTLQFEAAWALTNIASGSSGQTR-IVVDYGAVNVLVGLLSGS 573
+ FL++ KNP + A L N+A G S R I V G++ L+G L S
Sbjct: 394 VRFLSDRKNPVCREMAVVLLANLAQGDSLAARAIAVQKGSIGNLLGFLEDS 444
>AF521670-1|AAN03446.1| 1999|Homo sapiens SWI/SNF chromatin remodeling
complex subunit OSA1 protein.
Length = 1999
Score = 33.9 bits (74), Expect = 0.45
Identities = 19/51 (37%), Positives = 27/51 (52%), Gaps = 1/51 (1%)
Frame = +1
Query: 424 IEFLTNHKNPTLQFEAAWALTNIASGSSGQTR-IVVDYGAVNVLVGLLSGS 573
+ FL++ KNP + A L N+A G S R I V G++ L+G L S
Sbjct: 1866 VRFLSDRKNPVCREMAVVLLANLAQGDSLAARAIAVQKGSIGNLLGFLEDS 1916
>AF265208-1|AAF75765.1| 1927|Homo sapiens SWI-SNF complex protein p270
protein.
Length = 1927
Score = 33.9 bits (74), Expect = 0.45
Identities = 19/51 (37%), Positives = 27/51 (52%), Gaps = 1/51 (1%)
Frame = +1
Query: 424 IEFLTNHKNPTLQFEAAWALTNIASGSSGQTR-IVVDYGAVNVLVGLLSGS 573
+ FL++ KNP + A L N+A G S R I V G++ L+G L S
Sbjct: 1794 VRFLSDRKNPVCREMAVVLLANLAQGDSLAARAIAVQKGSIGNLLGFLEDS 1844
>AF231056-1|AAG33967.1| 2285|Homo sapiens BRG1-Associated Factor 250a
protein.
Length = 2285
Score = 33.9 bits (74), Expect = 0.45
Identities = 19/51 (37%), Positives = 27/51 (52%), Gaps = 1/51 (1%)
Frame = +1
Query: 424 IEFLTNHKNPTLQFEAAWALTNIASGSSGQTR-IVVDYGAVNVLVGLLSGS 573
+ FL++ KNP + A L N+A G S R I V G++ L+G L S
Sbjct: 2152 VRFLSDRKNPVCREMAVVLLANLAQGDSLAARAIAVQKGSIGNLLGFLEDS 2202
>AF219114-1|AAG17549.2| 1939|Homo sapiens chromatin remodelling factor
p250 protein.
Length = 1939
Score = 33.9 bits (74), Expect = 0.45
Identities = 19/51 (37%), Positives = 27/51 (52%), Gaps = 1/51 (1%)
Frame = +1
Query: 424 IEFLTNHKNPTLQFEAAWALTNIASGSSGQTR-IVVDYGAVNVLVGLLSGS 573
+ FL++ KNP + A L N+A G S R I V G++ L+G L S
Sbjct: 1806 VRFLSDRKNPVCREMAVVLLANLAQGDSLAARAIAVQKGSIGNLLGFLEDS 1856
>AF268913-1|AAK54505.1| 1685|Homo sapiens OSA1 nuclear protein
protein.
Length = 1685
Score = 32.3 bits (70), Expect = 1.4
Identities = 18/51 (35%), Positives = 27/51 (52%), Gaps = 1/51 (1%)
Frame = +1
Query: 424 IEFLTNHKNPTLQFEAAWALTNIASGSSGQTR-IVVDYGAVNVLVGLLSGS 573
+ FL++ +NP + A L N+A G S R I V G++ L+G L S
Sbjct: 1552 VRFLSDRENPVCREMAVVLLANLAQGDSLAARAIAVQKGSIGNLLGFLEDS 1602
>L09190-1|AAA65582.1| 1898|Homo sapiens trichohyalin protein.
Length = 1898
Score = 31.1 bits (67), Expect = 3.2
Identities = 14/30 (46%), Positives = 21/30 (70%)
Frame = +1
Query: 115 LSADELRRRREEEGVQLRKQKREQQLFKRR 204
L ELRR R+EE Q ++ +REQQL +++
Sbjct: 281 LERQELRRERQEEEQQQQRLRREQQLRRKQ 310
>AL589986-1|CAH70024.1| 1943|Homo sapiens trichohyalin protein.
Length = 1943
Score = 31.1 bits (67), Expect = 3.2
Identities = 14/30 (46%), Positives = 21/30 (70%)
Frame = +1
Query: 115 LSADELRRRREEEGVQLRKQKREQQLFKRR 204
L ELRR R+EE Q ++ +REQQL +++
Sbjct: 281 LERQELRRERQEEEQQQQRLRREQQLRRKQ 310
>AM156947-1|CAJ42307.1| 1221|Homo sapiens centrosome and spindle
pole associated protein 1 protein.
Length = 1221
Score = 30.7 bits (66), Expect = 4.2
Identities = 32/98 (32%), Positives = 46/98 (46%), Gaps = 3/98 (3%)
Frame = +1
Query: 112 GLSADELRRRREEEGVQLRKQKREQQLFKRRNVNLPGTNAAGAASQEDINISPSDCITPD 291
G + ++RR+E+ ++L +Q EQQ KRR +L AA A +D SP D +
Sbjct: 375 GEDRELIQRRKEKYRLELLEQMAEQQRNKRREKDLELRVAASGA--QDPEKSP-DRLKQF 431
Query: 292 MVLAVYLDN---PEEQVIATQKFRKLLSKEPNPPIDAV 396
V + + PE IA Q LS PPI +V
Sbjct: 432 SVAPRHFEEMIPPERPRIAFQTPLPPLSAPSVPPIPSV 469
>AJ583433-1|CAE47426.1| 876|Homo sapiens centrosome spindle pole
associated protein protein.
Length = 876
Score = 30.7 bits (66), Expect = 4.2
Identities = 32/98 (32%), Positives = 46/98 (46%), Gaps = 3/98 (3%)
Frame = +1
Query: 112 GLSADELRRRREEEGVQLRKQKREQQLFKRRNVNLPGTNAAGAASQEDINISPSDCITPD 291
G + ++RR+E+ ++L +Q EQQ KRR +L AA A +D SP D +
Sbjct: 81 GEDRELIQRRKEKYRLELLEQMAEQQRNKRREKDLELRVAASGA--QDPEKSP-DRLKQF 137
Query: 292 MVLAVYLDN---PEEQVIATQKFRKLLSKEPNPPIDAV 396
V + + PE IA Q LS PPI +V
Sbjct: 138 SVAPRHFEEMIPPERPRIAFQTPLPPLSAPSVPPIPSV 175
>BC131591-1|AAI31592.1| 890|Homo sapiens PACS2 protein protein.
Length = 890
Score = 29.5 bits (63), Expect = 9.7
Identities = 25/90 (27%), Positives = 45/90 (50%)
Frame = +1
Query: 139 RREEEGVQLRKQKREQQLFKRRNVNLPGTNAAGAASQEDINISPSDCITPDMVLAVYLDN 318
+RE +Q+ Q+R++ +K R + T AAG+ S ++ PS+ VL++
Sbjct: 114 KREGNKLQIMLQRRKR--YKNRTILGYKTLAAGSISMAEVMQHPSE---GGQVLSLCSSI 168
Query: 319 PEEQVIATQKFRKLLSKEPNPPIDAVIQSG 408
E V A + + LS +P D+ +Q+G
Sbjct: 169 KEAPVKAAEIWIASLSSQPIDHEDSTMQAG 198
>BC065220-1|AAH65220.2| 889|Homo sapiens phosphofurin acidic
cluster sorting protein 2 protein.
Length = 889
Score = 29.5 bits (63), Expect = 9.7
Identities = 25/90 (27%), Positives = 45/90 (50%)
Frame = +1
Query: 139 RREEEGVQLRKQKREQQLFKRRNVNLPGTNAAGAASQEDINISPSDCITPDMVLAVYLDN 318
+RE +Q+ Q+R++ +K R + T AAG+ S ++ PS+ VL++
Sbjct: 105 KREGNKLQIMLQRRKR--YKNRTILGYKTLAAGSISMAEVMQHPSE---GGQVLSLCSSI 159
Query: 319 PEEQVIATQKFRKLLSKEPNPPIDAVIQSG 408
E V A + + LS +P D+ +Q+G
Sbjct: 160 KEAPVKAAEIWIASLSSQPIDHEDSTMQAG 189
>AY320284-1|AAQ83882.2| 889|Homo sapiens PACS2 protein.
Length = 889
Score = 29.5 bits (63), Expect = 9.7
Identities = 25/90 (27%), Positives = 45/90 (50%)
Frame = +1
Query: 139 RREEEGVQLRKQKREQQLFKRRNVNLPGTNAAGAASQEDINISPSDCITPDMVLAVYLDN 318
+RE +Q+ Q+R++ +K R + T AAG+ S ++ PS+ VL++
Sbjct: 105 KREGNKLQIMLQRRKR--YKNRTILGYKTLAAGSISMAEVMQHPSE---GGQVLSLCSSI 159
Query: 319 PEEQVIATQKFRKLLSKEPNPPIDAVIQSG 408
E V A + + LS +P D+ +Q+G
Sbjct: 160 KEAPVKAAEIWIASLSSQPIDHEDSTMQAG 189
>AB011174-1|BAA25528.1| 962|Homo sapiens KIAA0602 protein protein.
Length = 962
Score = 29.5 bits (63), Expect = 9.7
Identities = 25/90 (27%), Positives = 45/90 (50%)
Frame = +1
Query: 139 RREEEGVQLRKQKREQQLFKRRNVNLPGTNAAGAASQEDINISPSDCITPDMVLAVYLDN 318
+RE +Q+ Q+R++ +K R + T AAG+ S ++ PS+ VL++
Sbjct: 163 KREGNKLQIMLQRRKR--YKNRTILGYKTLAAGSISMAEVMQHPSE---GGQVLSLCSSI 217
Query: 319 PEEQVIATQKFRKLLSKEPNPPIDAVIQSG 408
E V A + + LS +P D+ +Q+G
Sbjct: 218 KEAPVKAAEIWIASLSSQPIDHEDSTMQAG 247
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 78,726,561
Number of Sequences: 237096
Number of extensions: 1486313
Number of successful extensions: 5254
Number of sequences better than 10.0: 74
Number of HSP's better than 10.0 without gapping: 4456
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5104
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 6466646650
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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