Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= bmnc25k22
(605 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X90761-1|CAA62284.1| 448|Homo sapiens HHa2 hair keratin type I ... 30 5.5
X81419-1|CAA57179.1| 405|Homo sapiens hair type I acidic kerati... 30 5.5
DQ176850-1|ABA12209.1| 1416|Homo sapiens phospholipase C-eta2 pr... 30 5.5
BC128207-1|AAI28208.1| 1032|Homo sapiens PLCH2 protein protein. 30 5.5
BC043358-1|AAH43358.1| 1238|Homo sapiens PLCH2 protein protein. 30 5.5
AK122589-1|BAC56930.1| 1129|Homo sapiens FLJ00414 protein protein. 30 5.5
AB007919-1|BAA32295.3| 1182|Homo sapiens KIAA0450 protein protein. 30 5.5
U17690-2|AAB48379.1| 840|Homo sapiens neurofibromatosis 1 protein. 30 7.3
U17690-1|AAB48380.1| 861|Homo sapiens neurofibromatosis 1 protein. 30 7.3
M89914-1|AAA59925.1| 2839|Homo sapiens neurofibromin protein. 30 7.3
M82814-1|AAA59924.1| 2818|Homo sapiens GAP-related protein protein. 30 7.3
M61213-1|AAA59923.1| 482|Homo sapiens neurofibromatosis protein... 30 7.3
M60915-2|AAA59922.1| 378|Homo sapiens neurofibromatosis protein... 30 7.3
M60915-1|AAA59921.1| 399|Homo sapiens neurofibromatosis protein... 30 7.3
M38107-1|AAB59558.1| 2503|Homo sapiens neurofibromatosis protein... 30 7.3
M38106-1|AAA74897.1| 2485|Homo sapiens neurofibromatosis type 1 ... 30 7.3
BC013144-1|AAH13144.1| 797|Homo sapiens transient receptor pote... 30 7.3
BC008836-1|AAH08836.2| 263|Homo sapiens TRPC4AP protein protein. 30 7.3
BC001323-1|AAH01323.1| 312|Homo sapiens TRPC4AP protein protein. 30 7.3
AY796305-1|AAV50004.1| 2818|Homo sapiens neurofibromin 1 (neurof... 30 7.3
AL132825-7|CAC14946.1| 797|Homo sapiens transient receptor pote... 30 7.3
AB209336-1|BAD92573.1| 968|Homo sapiens neurofibromin variant p... 30 7.3
U69668-1|AAB48030.1| 2363|Homo sapiens Tpr protein. 29 9.6
BC018147-1|AAH18147.1| 666|Homo sapiens Leo1, Paf1/RNA polymera... 29 9.6
AY302186-1|AAP68819.1| 666|Homo sapiens replicative senescence ... 29 9.6
AL596220-1|CAI13119.1| 2363|Homo sapiens translocated promoter r... 29 9.6
AL450426-6|CAH72414.1| 318|Homo sapiens olfactory receptor, fam... 29 9.6
AL133553-3|CAI17859.1| 2363|Homo sapiens translocated promoter r... 29 9.6
AB065710-1|BAC05932.1| 318|Homo sapiens seven transmembrane hel... 29 9.6
>X90761-1|CAA62284.1| 448|Homo sapiens HHa2 hair keratin type I
intermediate filament protein.
Length = 448
Score = 30.3 bits (65), Expect = 5.5
Identities = 18/52 (34%), Positives = 29/52 (55%), Gaps = 3/52 (5%)
Frame = +2
Query: 149 LNQEDCVMLKNLSNLASKFFNVRCVADTLEVMLEA---LRNNIELVQPESDA 295
LNQ+ + L N S ++R +TLE+ L+A LR+++E ES+A
Sbjct: 294 LNQQVATSSEQLQNYQSDIIDLRRTVNTLEIELQAQHSLRDSLENTLTESEA 345
>X81419-1|CAA57179.1| 405|Homo sapiens hair type I acidic keratin
protein.
Length = 405
Score = 30.3 bits (65), Expect = 5.5
Identities = 18/52 (34%), Positives = 29/52 (55%), Gaps = 3/52 (5%)
Frame = +2
Query: 149 LNQEDCVMLKNLSNLASKFFNVRCVADTLEVMLEA---LRNNIELVQPESDA 295
LNQ+ + L N S ++R +TLE+ L+A LR+++E ES+A
Sbjct: 251 LNQQVATSSEQLQNYQSDIIDLRRTVNTLEIELQAQHSLRDSLENTLTESEA 302
>DQ176850-1|ABA12209.1| 1416|Homo sapiens phospholipase C-eta2
protein.
Length = 1416
Score = 30.3 bits (65), Expect = 5.5
Identities = 19/71 (26%), Positives = 35/71 (49%), Gaps = 2/71 (2%)
Frame = +2
Query: 392 KNKNIKTLFDLYNDRLPINFLDT--SATSPAVRKTPGKRSAEDDLLPTRSNKRANRPEIS 565
+ K + L D+ D+L ++ + + + T P+ + GK + LP ++ A E+S
Sbjct: 428 QKKMAQYLTDILGDKLDLSSVSSEDATTLPSPQMLKGKILVKGKKLPANISEDAEEGEVS 487
Query: 566 VISSEDEQEDD 598
S DE +DD
Sbjct: 488 DEDSADEIDDD 498
>BC128207-1|AAI28208.1| 1032|Homo sapiens PLCH2 protein protein.
Length = 1032
Score = 30.3 bits (65), Expect = 5.5
Identities = 19/71 (26%), Positives = 35/71 (49%), Gaps = 2/71 (2%)
Frame = +2
Query: 392 KNKNIKTLFDLYNDRLPINFLDT--SATSPAVRKTPGKRSAEDDLLPTRSNKRANRPEIS 565
+ K + L D+ D+L ++ + + + T P+ + GK + LP ++ A E+S
Sbjct: 313 QKKMAQYLTDILGDKLDLSSVSSEDATTLPSPQMLKGKILVKGKKLPANISEDAEEGEVS 372
Query: 566 VISSEDEQEDD 598
S DE +DD
Sbjct: 373 DEDSADEIDDD 383
>BC043358-1|AAH43358.1| 1238|Homo sapiens PLCH2 protein protein.
Length = 1238
Score = 30.3 bits (65), Expect = 5.5
Identities = 19/71 (26%), Positives = 35/71 (49%), Gaps = 2/71 (2%)
Frame = +2
Query: 392 KNKNIKTLFDLYNDRLPINFLDT--SATSPAVRKTPGKRSAEDDLLPTRSNKRANRPEIS 565
+ K + L D+ D+L ++ + + + T P+ + GK + LP ++ A E+S
Sbjct: 286 QKKMAQYLTDILGDKLDLSSVSSEDATTLPSPQMLKGKILVKGKKLPANISEDAEEGEVS 345
Query: 566 VISSEDEQEDD 598
S DE +DD
Sbjct: 346 DEDSADEIDDD 356
>AK122589-1|BAC56930.1| 1129|Homo sapiens FLJ00414 protein protein.
Length = 1129
Score = 30.3 bits (65), Expect = 5.5
Identities = 19/71 (26%), Positives = 35/71 (49%), Gaps = 2/71 (2%)
Frame = +2
Query: 392 KNKNIKTLFDLYNDRLPINFLDT--SATSPAVRKTPGKRSAEDDLLPTRSNKRANRPEIS 565
+ K + L D+ D+L ++ + + + T P+ + GK + LP ++ A E+S
Sbjct: 346 QKKMAQYLTDILGDKLDLSSVSSEDATTLPSPQMLKGKILVKGKKLPANISEDAEEGEVS 405
Query: 566 VISSEDEQEDD 598
S DE +DD
Sbjct: 406 DEDSADEIDDD 416
>AB007919-1|BAA32295.3| 1182|Homo sapiens KIAA0450 protein protein.
Length = 1182
Score = 30.3 bits (65), Expect = 5.5
Identities = 19/71 (26%), Positives = 35/71 (49%), Gaps = 2/71 (2%)
Frame = +2
Query: 392 KNKNIKTLFDLYNDRLPINFLDT--SATSPAVRKTPGKRSAEDDLLPTRSNKRANRPEIS 565
+ K + L D+ D+L ++ + + + T P+ + GK + LP ++ A E+S
Sbjct: 454 QKKMAQYLTDILGDKLDLSSVSSEDATTLPSPQMLKGKILVKGKKLPANISEDAEEGEVS 513
Query: 566 VISSEDEQEDD 598
S DE +DD
Sbjct: 514 DEDSADEIDDD 524
>U17690-2|AAB48379.1| 840|Homo sapiens neurofibromatosis 1 protein.
Length = 840
Score = 29.9 bits (64), Expect = 7.3
Identities = 15/49 (30%), Positives = 28/49 (57%), Gaps = 1/49 (2%)
Frame = +2
Query: 23 LRLIEKALATLTNRLHITTIDQLKKFRDYLNSDADAGEFQIFLN-QEDC 166
L+L+ K L ++ N + T + ++ F D++ S+ DA + FL+ DC
Sbjct: 668 LKLMSKILQSIANHVLFTKEEHMRPFNDFVKSNFDAAR-RFFLDIASDC 715
>U17690-1|AAB48380.1| 861|Homo sapiens neurofibromatosis 1 protein.
Length = 861
Score = 29.9 bits (64), Expect = 7.3
Identities = 15/49 (30%), Positives = 28/49 (57%), Gaps = 1/49 (2%)
Frame = +2
Query: 23 LRLIEKALATLTNRLHITTIDQLKKFRDYLNSDADAGEFQIFLN-QEDC 166
L+L+ K L ++ N + T + ++ F D++ S+ DA + FL+ DC
Sbjct: 689 LKLMSKILQSIANHVLFTKEEHMRPFNDFVKSNFDAAR-RFFLDIASDC 736
>M89914-1|AAA59925.1| 2839|Homo sapiens neurofibromin protein.
Length = 2839
Score = 29.9 bits (64), Expect = 7.3
Identities = 15/49 (30%), Positives = 28/49 (57%), Gaps = 1/49 (2%)
Frame = +2
Query: 23 LRLIEKALATLTNRLHITTIDQLKKFRDYLNSDADAGEFQIFLN-QEDC 166
L+L+ K L ++ N + T + ++ F D++ S+ DA + FL+ DC
Sbjct: 1439 LKLMSKILQSIANHVLFTKEEHMRPFNDFVKSNFDAAR-RFFLDIASDC 1486
>M82814-1|AAA59924.1| 2818|Homo sapiens GAP-related protein protein.
Length = 2818
Score = 29.9 bits (64), Expect = 7.3
Identities = 15/49 (30%), Positives = 28/49 (57%), Gaps = 1/49 (2%)
Frame = +2
Query: 23 LRLIEKALATLTNRLHITTIDQLKKFRDYLNSDADAGEFQIFLN-QEDC 166
L+L+ K L ++ N + T + ++ F D++ S+ DA + FL+ DC
Sbjct: 1418 LKLMSKILQSIANHVLFTKEEHMRPFNDFVKSNFDAAR-RFFLDIASDC 1465
>M61213-1|AAA59923.1| 482|Homo sapiens neurofibromatosis protein
type 1 protein.
Length = 482
Score = 29.9 bits (64), Expect = 7.3
Identities = 15/49 (30%), Positives = 28/49 (57%), Gaps = 1/49 (2%)
Frame = +2
Query: 23 LRLIEKALATLTNRLHITTIDQLKKFRDYLNSDADAGEFQIFLN-QEDC 166
L+L+ K L ++ N + T + ++ F D++ S+ DA + FL+ DC
Sbjct: 323 LKLMSKILQSIANHVLFTKEEHMRPFNDFVKSNFDAAR-RFFLDIASDC 370
>M60915-2|AAA59922.1| 378|Homo sapiens neurofibromatosis protein
type 1 protein.
Length = 378
Score = 29.9 bits (64), Expect = 7.3
Identities = 15/49 (30%), Positives = 28/49 (57%), Gaps = 1/49 (2%)
Frame = +2
Query: 23 LRLIEKALATLTNRLHITTIDQLKKFRDYLNSDADAGEFQIFLN-QEDC 166
L+L+ K L ++ N + T + ++ F D++ S+ DA + FL+ DC
Sbjct: 251 LKLMSKILQSIANHVLFTKEEHMRPFNDFVKSNFDAAR-RFFLDIASDC 298
>M60915-1|AAA59921.1| 399|Homo sapiens neurofibromatosis protein
type 1 protein.
Length = 399
Score = 29.9 bits (64), Expect = 7.3
Identities = 15/49 (30%), Positives = 28/49 (57%), Gaps = 1/49 (2%)
Frame = +2
Query: 23 LRLIEKALATLTNRLHITTIDQLKKFRDYLNSDADAGEFQIFLN-QEDC 166
L+L+ K L ++ N + T + ++ F D++ S+ DA + FL+ DC
Sbjct: 272 LKLMSKILQSIANHVLFTKEEHMRPFNDFVKSNFDAAR-RFFLDIASDC 319
>M38107-1|AAB59558.1| 2503|Homo sapiens neurofibromatosis protein type
1 protein.
Length = 2503
Score = 29.9 bits (64), Expect = 7.3
Identities = 15/49 (30%), Positives = 28/49 (57%), Gaps = 1/49 (2%)
Frame = +2
Query: 23 LRLIEKALATLTNRLHITTIDQLKKFRDYLNSDADAGEFQIFLN-QEDC 166
L+L+ K L ++ N + T + ++ F D++ S+ DA + FL+ DC
Sbjct: 1084 LKLMSKILQSIANHVLFTKEEHMRPFNDFVKSNFDAAR-RFFLDIASDC 1131
>M38106-1|AAA74897.1| 2485|Homo sapiens neurofibromatosis type 1
protein protein.
Length = 2485
Score = 29.9 bits (64), Expect = 7.3
Identities = 15/49 (30%), Positives = 28/49 (57%), Gaps = 1/49 (2%)
Frame = +2
Query: 23 LRLIEKALATLTNRLHITTIDQLKKFRDYLNSDADAGEFQIFLN-QEDC 166
L+L+ K L ++ N + T + ++ F D++ S+ DA + FL+ DC
Sbjct: 1084 LKLMSKILQSIANHVLFTKEEHMRPFNDFVKSNFDAAR-RFFLDIASDC 1131
>BC013144-1|AAH13144.1| 797|Homo sapiens transient receptor
potential cation channel, subfamily C, member 4
associated p protein.
Length = 797
Score = 29.9 bits (64), Expect = 7.3
Identities = 19/53 (35%), Positives = 29/53 (54%)
Frame = +2
Query: 80 IDQLKKFRDYLNSDADAGEFQIFLNQEDCVMLKNLSNLASKFFNVRCVADTLE 238
+D K+F Y+N+DA +FQ+FL Q + S+L VRCV +L+
Sbjct: 594 VDAFKRFNKYINTDA---KFQVFLKQIN-------SSLVDSNMLVRCVTLSLD 636
>BC008836-1|AAH08836.2| 263|Homo sapiens TRPC4AP protein protein.
Length = 263
Score = 29.9 bits (64), Expect = 7.3
Identities = 19/53 (35%), Positives = 29/53 (54%)
Frame = +2
Query: 80 IDQLKKFRDYLNSDADAGEFQIFLNQEDCVMLKNLSNLASKFFNVRCVADTLE 238
+D K+F Y+N+DA +FQ+FL Q + S+L VRCV +L+
Sbjct: 60 VDAFKRFNKYINTDA---KFQVFLKQIN-------SSLVDSNMLVRCVTLSLD 102
>BC001323-1|AAH01323.1| 312|Homo sapiens TRPC4AP protein protein.
Length = 312
Score = 29.9 bits (64), Expect = 7.3
Identities = 19/53 (35%), Positives = 29/53 (54%)
Frame = +2
Query: 80 IDQLKKFRDYLNSDADAGEFQIFLNQEDCVMLKNLSNLASKFFNVRCVADTLE 238
+D K+F Y+N+DA +FQ+FL Q + S+L VRCV +L+
Sbjct: 109 VDAFKRFNKYINTDA---KFQVFLKQIN-------SSLVDSNMLVRCVTLSLD 151
>AY796305-1|AAV50004.1| 2818|Homo sapiens neurofibromin 1
(neurofibromatosis, von Recklinghausen disease, Watson
disease) protein.
Length = 2818
Score = 29.9 bits (64), Expect = 7.3
Identities = 15/49 (30%), Positives = 28/49 (57%), Gaps = 1/49 (2%)
Frame = +2
Query: 23 LRLIEKALATLTNRLHITTIDQLKKFRDYLNSDADAGEFQIFLN-QEDC 166
L+L+ K L ++ N + T + ++ F D++ S+ DA + FL+ DC
Sbjct: 1418 LKLMSKILQSIANHVLFTKEEHMRPFNDFVKSNFDAAR-RFFLDIASDC 1465
>AL132825-7|CAC14946.1| 797|Homo sapiens transient receptor
potential cation channel, subfamily C, member 4
associated p protein.
Length = 797
Score = 29.9 bits (64), Expect = 7.3
Identities = 19/53 (35%), Positives = 29/53 (54%)
Frame = +2
Query: 80 IDQLKKFRDYLNSDADAGEFQIFLNQEDCVMLKNLSNLASKFFNVRCVADTLE 238
+D K+F Y+N+DA +FQ+FL Q + S+L VRCV +L+
Sbjct: 594 VDAFKRFNKYINTDA---KFQVFLKQIN-------SSLVDSNMLVRCVTLSLD 636
>AB209336-1|BAD92573.1| 968|Homo sapiens neurofibromin variant
protein.
Length = 968
Score = 29.9 bits (64), Expect = 7.3
Identities = 15/49 (30%), Positives = 28/49 (57%), Gaps = 1/49 (2%)
Frame = +2
Query: 23 LRLIEKALATLTNRLHITTIDQLKKFRDYLNSDADAGEFQIFLN-QEDC 166
L+L+ K L ++ N + T + ++ F D++ S+ DA + FL+ DC
Sbjct: 468 LKLMSKILQSIANHVLFTKEEHMRPFNDFVKSNFDAAR-RFFLDIASDC 515
>U69668-1|AAB48030.1| 2363|Homo sapiens Tpr protein.
Length = 2363
Score = 29.5 bits (63), Expect = 9.6
Identities = 13/49 (26%), Positives = 26/49 (53%)
Frame = +2
Query: 455 DTSATSPAVRKTPGKRSAEDDLLPTRSNKRANRPEISVISSEDEQEDDD 601
D+ TS +++ G ++ + + + ++ VI S+DE+EDDD
Sbjct: 1908 DSEETSQSLQIDLGPLQSDQQTTTSSQDGQGKGDDVIVIDSDDEEEDDD 1956
>BC018147-1|AAH18147.1| 666|Homo sapiens Leo1, Paf1/RNA polymerase
II complex component, homolog (S. cerevisiae) protein.
Length = 666
Score = 29.5 bits (63), Expect = 9.6
Identities = 17/45 (37%), Positives = 24/45 (53%)
Frame = +2
Query: 467 TSPAVRKTPGKRSAEDDLLPTRSNKRANRPEISVISSEDEQEDDD 601
TS + GKR AEDD +AN+ + S++E+EDDD
Sbjct: 629 TSDEEGEPSGKRKAEDD-------DKANKKHKKYVISDEEEEDDD 666
>AY302186-1|AAP68819.1| 666|Homo sapiens replicative senescence
downregulated leo1-like protein protein.
Length = 666
Score = 29.5 bits (63), Expect = 9.6
Identities = 17/45 (37%), Positives = 24/45 (53%)
Frame = +2
Query: 467 TSPAVRKTPGKRSAEDDLLPTRSNKRANRPEISVISSEDEQEDDD 601
TS + GKR AEDD +AN+ + S++E+EDDD
Sbjct: 629 TSDEEGEPSGKRKAEDD-------DKANKKHKKYVISDEEEEDDD 666
>AL596220-1|CAI13119.1| 2363|Homo sapiens translocated promoter region
(to activated MET oncogene) protein.
Length = 2363
Score = 29.5 bits (63), Expect = 9.6
Identities = 13/49 (26%), Positives = 26/49 (53%)
Frame = +2
Query: 455 DTSATSPAVRKTPGKRSAEDDLLPTRSNKRANRPEISVISSEDEQEDDD 601
D+ TS +++ G ++ + + + ++ VI S+DE+EDDD
Sbjct: 1908 DSEETSQSLQIDLGPLQSDQQTTTSSQDGQGKGDDVIVIDSDDEEEDDD 1956
>AL450426-6|CAH72414.1| 318|Homo sapiens olfactory receptor, family
13, subfamily C, member 5 protein.
Length = 318
Score = 29.5 bits (63), Expect = 9.6
Identities = 18/56 (32%), Positives = 29/56 (51%)
Frame = -3
Query: 396 FFMAS*SLLYMAMLYSGVVESLISCVIFMTIRRTASLSGCTNSILLRRASNITSNV 229
FF+ + S L + + + +L+S F++ R+T SLSGC + L A T V
Sbjct: 61 FFLGNLSFLDICYTTTSIPSTLVS---FLSERKTISLSGCAVQMFLSLAMGTTECV 113
>AL133553-3|CAI17859.1| 2363|Homo sapiens translocated promoter region
(to activated MET oncogene) protein.
Length = 2363
Score = 29.5 bits (63), Expect = 9.6
Identities = 13/49 (26%), Positives = 26/49 (53%)
Frame = +2
Query: 455 DTSATSPAVRKTPGKRSAEDDLLPTRSNKRANRPEISVISSEDEQEDDD 601
D+ TS +++ G ++ + + + ++ VI S+DE+EDDD
Sbjct: 1908 DSEETSQSLQIDLGPLQSDQQTTTSSQDGQGKGDDVIVIDSDDEEEDDD 1956
>AB065710-1|BAC05932.1| 318|Homo sapiens seven transmembrane helix
receptor protein.
Length = 318
Score = 29.5 bits (63), Expect = 9.6
Identities = 18/56 (32%), Positives = 29/56 (51%)
Frame = -3
Query: 396 FFMAS*SLLYMAMLYSGVVESLISCVIFMTIRRTASLSGCTNSILLRRASNITSNV 229
FF+ + S L + + + +L+S F++ R+T SLSGC + L A T V
Sbjct: 61 FFLGNLSFLDICYTTTSIPSTLVS---FLSERKTISLSGCAVQMFLSLAMGTTECV 113
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 74,962,592
Number of Sequences: 237096
Number of extensions: 1411423
Number of successful extensions: 3817
Number of sequences better than 10.0: 29
Number of HSP's better than 10.0 without gapping: 3596
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3805
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 6410414940
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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