Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= bmnc25b06
(532 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X05344-1|CAA28955.1| 412|Homo sapiens cathepsin D protein. 129 7e-30
M63138-1|AAA51922.1| 412|Homo sapiens cathepsin D protein. 129 7e-30
M11233-1|AAB59529.1| 412|Homo sapiens CTSD protein. 129 7e-30
CR456947-1|CAG33228.1| 412|Homo sapiens CTSD protein. 129 7e-30
BT020155-1|AAV38957.1| 412|Homo sapiens cathepsin D (lysosomal ... 129 7e-30
BT006910-1|AAP35556.1| 412|Homo sapiens cathepsin D (lysosomal ... 129 7e-30
BC016320-1|AAH16320.1| 412|Homo sapiens cathepsin D protein. 129 7e-30
BC017842-1|AAH17842.1| 420|Homo sapiens napsin A aspartic pepti... 113 5e-25
AF200345-1|AAF17081.1| 420|Homo sapiens aspartyl protease 4 pro... 112 6e-25
AF098484-1|AAD13215.1| 420|Homo sapiens napsin 1 precursor prot... 112 6e-25
AF090386-1|AAD04917.1| 420|Homo sapiens napsin A protein. 112 6e-25
BC111705-1|AAI11706.1| 464|Homo sapiens NAPSB protein protein. 102 9e-22
AF200344-1|AAF17080.1| 450|Homo sapiens aspartyl protease 3 pro... 102 9e-22
M26901-1|AAA60364.1| 403|Homo sapiens renin protein. 99 8e-21
M10152-1|AAD03461.1| 406|Homo sapiens renin protein. 99 8e-21
L00073-1|AAA60363.1| 406|Homo sapiens renin protein. 99 8e-21
CR536498-1|CAG38737.1| 406|Homo sapiens REN protein. 99 8e-21
BC047752-1|AAH47752.1| 406|Homo sapiens renin protein. 99 8e-21
BC033474-1|AAH33474.1| 406|Homo sapiens renin protein. 99 8e-21
AY436324-1|AAR03502.1| 403|Homo sapiens renin protein. 99 8e-21
AL592146-1|CAI16594.1| 406|Homo sapiens renin protein. 99 8e-21
AL592114-1|CAH71224.1| 406|Homo sapiens renin protein. 99 8e-21
J00287-1|AAA98529.1| 388|Homo sapiens PEP protein. 95 1e-19
BC029055-1|AAH29055.1| 388|Homo sapiens pepsinogen 5, group I (... 95 1e-19
M26032-1|AAA60061.1| 388|Homo sapiens pepsinogen A protein. 93 4e-19
U75272-1|AAB18273.1| 388|Homo sapiens gastricsin protein. 89 1e-17
M23077-1|AAA60063.1| 388|Homo sapiens pepsinogen C protein. 89 1e-17
M18667-1|AAA60062.1| 385|Homo sapiens pepsinogen protein. 89 1e-17
J04443-1|AAA60074.1| 388|Homo sapiens pepsinogen protein. 89 1e-17
BC073740-1|AAH73740.1| 388|Homo sapiens progastricsin (pepsinog... 89 1e-17
AL365205-1|CAI13181.1| 388|Homo sapiens progastricsin (pepsinog... 89 1e-17
M84424-1|AAA52300.1| 396|Homo sapiens cathepsin E protein. 87 4e-17
J05036-1|AAA52130.1| 396|Homo sapiens CTSE protein. 87 4e-17
BX571818-5|CAH73265.1| 363|Homo sapiens cathepsin E protein. 87 4e-17
BX571818-4|CAH73264.1| 396|Homo sapiens cathepsin E protein. 87 4e-17
BC042537-1|AAH42537.1| 396|Homo sapiens cathepsin E protein. 87 4e-17
AJ250717-1|CAB82850.1| 396|Homo sapiens procathepsin E protein. 87 4e-17
AJ250716-1|CAB82849.1| 363|Homo sapiens cathepsin E, alternativ... 87 4e-17
BC042578-1|AAH42578.1| 104|Homo sapiens PGC protein protein. 60 5e-09
X00063-1|CAA24937.1| 300|Homo sapiens protein ( Human kidney mR... 45 1e-04
AL365205-3|CAM16152.1| 86|Homo sapiens progastricsin (pepsinog... 39 0.013
BC014453-1|AAH14453.1| 518|Homo sapiens beta-site APP-cleaving ... 38 0.022
AY358927-1|AAQ89286.1| 518|Homo sapiens BACE2 protein. 38 0.022
AF212252-1|AAG41783.1| 439|Homo sapiens CDA13 protein. 38 0.022
AF204944-1|AAF26368.1| 518|Homo sapiens transmembrane aspartic ... 38 0.022
AF200342-1|AAF17078.1| 518|Homo sapiens aspartyl protease 1 pro... 38 0.022
AF200192-1|AAF13714.1| 518|Homo sapiens memapsin 1 protein. 38 0.022
AF188277-1|AAF35836.1| 396|Homo sapiens aspartyl protease protein. 38 0.022
AF188276-1|AAF35835.1| 468|Homo sapiens aspartyl protease protein. 38 0.022
AF178532-1|AAF29494.1| 518|Homo sapiens aspartyl protease protein. 38 0.022
AF117892-1|AAD45240.1| 518|Homo sapiens aspartic-like protease ... 38 0.022
AF050171-1|AAD45963.1| 518|Homo sapiens aspartyl protease protein. 38 0.022
DQ007053-1|AAY16982.1| 501|Homo sapiens beta-site APP-cleaving ... 36 0.12
BC065492-1|AAH65492.1| 501|Homo sapiens beta-site APP-cleaving ... 36 0.12
AF338817-1|AAK38375.1| 457|Homo sapiens beta-site APP cleaving ... 36 0.12
AF338816-1|AAK38374.1| 476|Homo sapiens beta-site APP cleaving ... 36 0.12
AF204943-1|AAF26367.1| 501|Homo sapiens transmembrane aspartic ... 36 0.12
AF201468-1|AAF18982.1| 501|Homo sapiens APP beta-secretase prot... 36 0.12
AF200343-1|AAF17079.1| 501|Homo sapiens aspartyl protease 2 pro... 36 0.12
AF200193-1|AAF13715.1| 488|Homo sapiens memapsin 2 protein. 36 0.12
AF190725-1|AAF04142.1| 501|Homo sapiens beta-site APP cleaving ... 36 0.12
AB089958-1|BAC81826.1| 127|Homo sapiens beta-site APP cleaving ... 36 0.12
AB050438-1|BAB40933.1| 432|Homo sapiens beta-site APP cleaving ... 36 0.12
AB050437-1|BAB40932.1| 457|Homo sapiens beta-site APP cleaving ... 36 0.12
AB050436-1|BAB40931.1| 476|Homo sapiens beta-site APP cleaving ... 36 0.12
AB032975-1|BAA86463.2| 532|Homo sapiens KIAA1149 protein protein. 36 0.12
AK075539-1|BAC11682.1| 423|Homo sapiens protein ( Homo sapiens ... 35 0.16
BC036084-1|AAH36084.1| 501|Homo sapiens beta-site APP-cleaving ... 35 0.21
BC030606-1|AAH30606.2| 514|Homo sapiens coiled-coil domain cont... 31 3.3
BC047091-1|AAH47091.1| 458|Homo sapiens zinc finger protein 19 ... 29 7.7
AL834237-1|CAD38915.1| 339|Homo sapiens hypothetical protein pr... 29 7.7
AK057330-1|BAB71430.1| 446|Homo sapiens protein ( Homo sapiens ... 29 7.7
AK055567-1|BAB70957.1| 446|Homo sapiens protein ( Homo sapiens ... 29 7.7
>X05344-1|CAA28955.1| 412|Homo sapiens cathepsin D protein.
Length = 412
Score = 129 bits (311), Expect = 7e-30
Identities = 67/126 (53%), Positives = 81/126 (64%), Gaps = 11/126 (8%)
Frame = +3
Query: 183 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 329
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 330 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTS 509
L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS C +IAC +H+KY+S KS++
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSST 130
Query: 510 YVANGT 527
YV NGT
Sbjct: 131 YVKNGT 136
>M63138-1|AAA51922.1| 412|Homo sapiens cathepsin D protein.
Length = 412
Score = 129 bits (311), Expect = 7e-30
Identities = 67/126 (53%), Positives = 81/126 (64%), Gaps = 11/126 (8%)
Frame = +3
Query: 183 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 329
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 330 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTS 509
L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS C +IAC +H+KY+S KS++
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSST 130
Query: 510 YVANGT 527
YV NGT
Sbjct: 131 YVKNGT 136
>M11233-1|AAB59529.1| 412|Homo sapiens CTSD protein.
Length = 412
Score = 129 bits (311), Expect = 7e-30
Identities = 67/126 (53%), Positives = 81/126 (64%), Gaps = 11/126 (8%)
Frame = +3
Query: 183 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 329
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 330 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTS 509
L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS C +IAC +H+KY+S KS++
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSST 130
Query: 510 YVANGT 527
YV NGT
Sbjct: 131 YVKNGT 136
>CR456947-1|CAG33228.1| 412|Homo sapiens CTSD protein.
Length = 412
Score = 129 bits (311), Expect = 7e-30
Identities = 67/126 (53%), Positives = 81/126 (64%), Gaps = 11/126 (8%)
Frame = +3
Query: 183 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 329
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 330 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTS 509
L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS C +IAC +H+KY+S KS++
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSST 130
Query: 510 YVANGT 527
YV NGT
Sbjct: 131 YVKNGT 136
>BT020155-1|AAV38957.1| 412|Homo sapiens cathepsin D (lysosomal
aspartyl protease) protein.
Length = 412
Score = 129 bits (311), Expect = 7e-30
Identities = 67/126 (53%), Positives = 81/126 (64%), Gaps = 11/126 (8%)
Frame = +3
Query: 183 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 329
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 330 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTS 509
L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS C +IAC +H+KY+S KS++
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSST 130
Query: 510 YVANGT 527
YV NGT
Sbjct: 131 YVKNGT 136
>BT006910-1|AAP35556.1| 412|Homo sapiens cathepsin D (lysosomal
aspartyl protease) protein.
Length = 412
Score = 129 bits (311), Expect = 7e-30
Identities = 67/126 (53%), Positives = 81/126 (64%), Gaps = 11/126 (8%)
Frame = +3
Query: 183 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 329
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 330 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTS 509
L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS C +IAC +H+KY+S KS++
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSST 130
Query: 510 YVANGT 527
YV NGT
Sbjct: 131 YVKNGT 136
>BC016320-1|AAH16320.1| 412|Homo sapiens cathepsin D protein.
Length = 412
Score = 129 bits (311), Expect = 7e-30
Identities = 67/126 (53%), Positives = 81/126 (64%), Gaps = 11/126 (8%)
Frame = +3
Query: 183 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 329
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 330 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTS 509
L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS C +IAC +H+KY+S KS++
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSST 130
Query: 510 YVANGT 527
YV NGT
Sbjct: 131 YVKNGT 136
>BC017842-1|AAH17842.1| 420|Homo sapiens napsin A aspartic
peptidase protein.
Length = 420
Score = 113 bits (271), Expect = 5e-25
Identities = 54/118 (45%), Positives = 76/118 (64%), Gaps = 5/118 (4%)
Frame = +3
Query: 192 IASSVMALYRVPLHRMKTARTHFHEVG---TELELLRLKYDVTGPSP--EPLSNYLDAQY 356
+ S L R+PLHR++ R + + EL +L G P PLSNY D QY
Sbjct: 19 VEPSGATLIRIPLHRVQPGRRTLNLLRGWREPAELPKLGAPSPGDKPIFVPLSNYRDVQY 78
Query: 357 YGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQ 530
+G I +GTPPQ+F V FDTGSSNLWVPS++CH+ ++ C LH+++D + S+S+ ANGT+
Sbjct: 79 FGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHHRFDPKASSSFQANGTK 136
>AF200345-1|AAF17081.1| 420|Homo sapiens aspartyl protease 4
protein.
Length = 420
Score = 112 bits (270), Expect = 6e-25
Identities = 54/118 (45%), Positives = 76/118 (64%), Gaps = 5/118 (4%)
Frame = +3
Query: 192 IASSVMALYRVPLHRMKTARTHFHEVG---TELELLRLKYDVTGPSP--EPLSNYLDAQY 356
+ S L R+PLHR++ R + + EL +L G P PLSNY D QY
Sbjct: 19 VEPSGATLIRIPLHRVQPGRRILNLLRGWREPAELPKLGAPSPGDKPIFVPLSNYRDVQY 78
Query: 357 YGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQ 530
+G I +GTPPQ+F V FDTGSSNLWVPS++CH+ ++ C LH+++D + S+S+ ANGT+
Sbjct: 79 FGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHHRFDPKASSSFQANGTK 136
>AF098484-1|AAD13215.1| 420|Homo sapiens napsin 1 precursor
protein.
Length = 420
Score = 112 bits (270), Expect = 6e-25
Identities = 54/118 (45%), Positives = 76/118 (64%), Gaps = 5/118 (4%)
Frame = +3
Query: 192 IASSVMALYRVPLHRMKTARTHFHEVG---TELELLRLKYDVTGPSP--EPLSNYLDAQY 356
+ S L R+PLHR++ R + + EL +L G P PLSNY D QY
Sbjct: 19 VEPSGATLIRIPLHRVQPGRRILNLLRGWREPAELPKLGAPSPGDKPIFVPLSNYRDVQY 78
Query: 357 YGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQ 530
+G I +GTPPQ+F V FDTGSSNLWVPS++CH+ ++ C LH+++D + S+S+ ANGT+
Sbjct: 79 FGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHHRFDPKASSSFQANGTK 136
>AF090386-1|AAD04917.1| 420|Homo sapiens napsin A protein.
Length = 420
Score = 112 bits (270), Expect = 6e-25
Identities = 54/118 (45%), Positives = 76/118 (64%), Gaps = 5/118 (4%)
Frame = +3
Query: 192 IASSVMALYRVPLHRMKTARTHFHEVG---TELELLRLKYDVTGPSP--EPLSNYLDAQY 356
+ S L R+PLHR++ R + + EL +L G P PLSNY D QY
Sbjct: 19 VEPSGATLIRIPLHRVQPGRRILNLLRGWREPAELPKLGAPSPGDKPIFVPLSNYRDVQY 78
Query: 357 YGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQ 530
+G I +GTPPQ+F V FDTGSSNLWVPS++CH+ ++ C LH+++D + S+S+ ANGT+
Sbjct: 79 FGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHHRFDPKASSSFQANGTK 136
>BC111705-1|AAI11706.1| 464|Homo sapiens NAPSB protein protein.
Length = 464
Score = 102 bits (244), Expect = 9e-22
Identities = 48/111 (43%), Positives = 71/111 (63%), Gaps = 5/111 (4%)
Frame = +3
Query: 213 LYRVPLHRMKTARTHFHEV---GTELELLRLKYDVTGPSPE--PLSNYLDAQYYGVISIG 377
L R+PL ++ R + + G EL +L G P PLS +LDAQY+G I +G
Sbjct: 22 LIRIPLRQVHPGRRTLNLLRGWGKPAELPKLGAPSPGDKPASVPLSKFLDAQYFGEIGLG 81
Query: 378 TPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQ 530
TPPQ+F V FDTGSSNLWVPS++CH+ ++ C H++++ S+S+ +GT+
Sbjct: 82 TPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWFHHRFNPNASSSFKPSGTK 132
>AF200344-1|AAF17080.1| 450|Homo sapiens aspartyl protease 3
protein.
Length = 450
Score = 102 bits (244), Expect = 9e-22
Identities = 48/111 (43%), Positives = 71/111 (63%), Gaps = 5/111 (4%)
Frame = +3
Query: 213 LYRVPLHRMKTARTHFHEV---GTELELLRLKYDVTGPSPE--PLSNYLDAQYYGVISIG 377
L R+PL ++ R + + G EL +L G P PLS +LDAQY+G I +G
Sbjct: 26 LIRIPLRQVHPGRRTLNLLRGWGKPAELPKLGAPSPGDKPASVPLSKFLDAQYFGEIGLG 85
Query: 378 TPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQ 530
TPPQ+F V FDTGSSNLWVPS++CH+ ++ C H++++ S+S+ +GT+
Sbjct: 86 TPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWFHHRFNPNASSSFKPSGTK 136
>M26901-1|AAA60364.1| 403|Homo sapiens renin protein.
Length = 403
Score = 99.1 bits (236), Expect = 8e-21
Identities = 42/67 (62%), Positives = 51/67 (76%)
Frame = +3
Query: 330 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTS 509
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S+S
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 510 YVANGTQ 530
Y NGT+
Sbjct: 138 YKHNGTE 144
>M10152-1|AAD03461.1| 406|Homo sapiens renin protein.
Length = 406
Score = 99.1 bits (236), Expect = 8e-21
Identities = 42/67 (62%), Positives = 51/67 (76%)
Frame = +3
Query: 330 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTS 509
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S+S
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 510 YVANGTQ 530
Y NGT+
Sbjct: 138 YKHNGTE 144
>L00073-1|AAA60363.1| 406|Homo sapiens renin protein.
Length = 406
Score = 99.1 bits (236), Expect = 8e-21
Identities = 42/67 (62%), Positives = 51/67 (76%)
Frame = +3
Query: 330 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTS 509
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S+S
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 510 YVANGTQ 530
Y NGT+
Sbjct: 138 YKHNGTE 144
>CR536498-1|CAG38737.1| 406|Homo sapiens REN protein.
Length = 406
Score = 99.1 bits (236), Expect = 8e-21
Identities = 42/67 (62%), Positives = 51/67 (76%)
Frame = +3
Query: 330 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTS 509
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S+S
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 510 YVANGTQ 530
Y NGT+
Sbjct: 138 YKHNGTE 144
>BC047752-1|AAH47752.1| 406|Homo sapiens renin protein.
Length = 406
Score = 99.1 bits (236), Expect = 8e-21
Identities = 42/67 (62%), Positives = 51/67 (76%)
Frame = +3
Query: 330 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTS 509
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S+S
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 510 YVANGTQ 530
Y NGT+
Sbjct: 138 YKHNGTE 144
>BC033474-1|AAH33474.1| 406|Homo sapiens renin protein.
Length = 406
Score = 99.1 bits (236), Expect = 8e-21
Identities = 42/67 (62%), Positives = 51/67 (76%)
Frame = +3
Query: 330 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTS 509
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S+S
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 510 YVANGTQ 530
Y NGT+
Sbjct: 138 YKHNGTE 144
>AY436324-1|AAR03502.1| 403|Homo sapiens renin protein.
Length = 403
Score = 99.1 bits (236), Expect = 8e-21
Identities = 42/67 (62%), Positives = 51/67 (76%)
Frame = +3
Query: 330 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTS 509
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S+S
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 510 YVANGTQ 530
Y NGT+
Sbjct: 138 YKHNGTE 144
>AL592146-1|CAI16594.1| 406|Homo sapiens renin protein.
Length = 406
Score = 99.1 bits (236), Expect = 8e-21
Identities = 42/67 (62%), Positives = 51/67 (76%)
Frame = +3
Query: 330 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTS 509
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S+S
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 510 YVANGTQ 530
Y NGT+
Sbjct: 138 YKHNGTE 144
>AL592114-1|CAH71224.1| 406|Homo sapiens renin protein.
Length = 406
Score = 99.1 bits (236), Expect = 8e-21
Identities = 42/67 (62%), Positives = 51/67 (76%)
Frame = +3
Query: 330 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTS 509
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S+S
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 510 YVANGTQ 530
Y NGT+
Sbjct: 138 YKHNGTE 144
>J00287-1|AAA98529.1| 388|Homo sapiens PEP protein.
Length = 388
Score = 95.1 bits (226), Expect = 1e-19
Identities = 54/125 (43%), Positives = 72/125 (57%), Gaps = 12/125 (9%)
Frame = +3
Query: 174 LFFLALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRL-------KYDVTGPSP--- 323
L L L+A S +Y+VPL R K+ R E G + L+ KY +P
Sbjct: 4 LLLLGLVALSECIMYKVPLIRKKSLRRTLSERGLLKDFLKKHNLNPARKYFPQWEAPTLV 63
Query: 324 --EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSR 497
+PL NYLD +Y+G I IGTP Q F VVFDTGSSNLWVPS C +++AC HN+++
Sbjct: 64 DEQPLENYLDMEYFGTIGIGTPAQDFTVVFDTGSSNLWVPSVYC--SSLACTNHNRFNPE 121
Query: 498 KSTSY 512
S++Y
Sbjct: 122 DSSTY 126
>BC029055-1|AAH29055.1| 388|Homo sapiens pepsinogen 5, group I
(pepsinogen A) protein.
Length = 388
Score = 95.1 bits (226), Expect = 1e-19
Identities = 54/125 (43%), Positives = 72/125 (57%), Gaps = 12/125 (9%)
Frame = +3
Query: 174 LFFLALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRL-------KYDVTGPSP--- 323
L L L+A S +Y+VPL R K+ R E G + L+ KY +P
Sbjct: 4 LLLLGLVALSECIMYKVPLIRKKSLRRTLSERGLLKDFLKKHNLNPARKYFPQWEAPTLV 63
Query: 324 --EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSR 497
+PL NYLD +Y+G I IGTP Q F VVFDTGSSNLWVPS C +++AC HN+++
Sbjct: 64 DEQPLENYLDMEYFGTIGIGTPAQDFTVVFDTGSSNLWVPSVYC--SSLACTNHNRFNPE 121
Query: 498 KSTSY 512
S++Y
Sbjct: 122 DSSTY 126
>M26032-1|AAA60061.1| 388|Homo sapiens pepsinogen A protein.
Length = 388
Score = 93.5 bits (222), Expect = 4e-19
Identities = 53/125 (42%), Positives = 72/125 (57%), Gaps = 12/125 (9%)
Frame = +3
Query: 174 LFFLALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRL-------KYDVTGPSP--- 323
L L L+A S +Y+VPL R K+ R E G + L+ KY +P
Sbjct: 4 LLLLGLVALSECIMYKVPLIRKKSFRRTLSERGLLKDFLKKHNLNPARKYFPQWKAPTLV 63
Query: 324 --EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSR 497
+PL NYLD +Y+G I IGTP Q F V+FDTGSSNLWVPS C +++AC HN+++
Sbjct: 64 DEQPLENYLDMEYFGTIGIGTPAQDFTVLFDTGSSNLWVPSVYC--SSLACTNHNRFNPE 121
Query: 498 KSTSY 512
S++Y
Sbjct: 122 DSSTY 126
>U75272-1|AAB18273.1| 388|Homo sapiens gastricsin protein.
Length = 388
Score = 88.6 bits (210), Expect = 1e-17
Identities = 51/114 (44%), Positives = 70/114 (61%), Gaps = 9/114 (7%)
Frame = +3
Query: 210 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 362
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 363 VISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANG 524
ISIGTPPQ+F V+FDTGSSNLWVPS C + AC H++++ +S++Y NG
Sbjct: 76 EISIGTPPQNFLVLFDTGSSNLWVPSVYCQ--SQACTSHSRFNPSESSTYSTNG 127
>M23077-1|AAA60063.1| 388|Homo sapiens pepsinogen C protein.
Length = 388
Score = 88.6 bits (210), Expect = 1e-17
Identities = 51/114 (44%), Positives = 70/114 (61%), Gaps = 9/114 (7%)
Frame = +3
Query: 210 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 362
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 363 VISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANG 524
ISIGTPPQ+F V+FDTGSSNLWVPS C + AC H++++ +S++Y NG
Sbjct: 76 EISIGTPPQNFLVLFDTGSSNLWVPSVYCQ--SQACTSHSRFNPSESSTYSTNG 127
>M18667-1|AAA60062.1| 385|Homo sapiens pepsinogen protein.
Length = 385
Score = 88.6 bits (210), Expect = 1e-17
Identities = 51/114 (44%), Positives = 70/114 (61%), Gaps = 9/114 (7%)
Frame = +3
Query: 210 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 362
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 14 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 72
Query: 363 VISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANG 524
ISIGTPPQ+F V+FDTGSSNLWVPS C + AC H++++ +S++Y NG
Sbjct: 73 EISIGTPPQNFLVLFDTGSSNLWVPSVYCQ--SQACTSHSRFNPSESSTYSTNG 124
>J04443-1|AAA60074.1| 388|Homo sapiens pepsinogen protein.
Length = 388
Score = 88.6 bits (210), Expect = 1e-17
Identities = 51/114 (44%), Positives = 70/114 (61%), Gaps = 9/114 (7%)
Frame = +3
Query: 210 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 362
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 363 VISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANG 524
ISIGTPPQ+F V+FDTGSSNLWVPS C + AC H++++ +S++Y NG
Sbjct: 76 EISIGTPPQNFLVLFDTGSSNLWVPSVYCQ--SQACTSHSRFNPSESSTYSTNG 127
>BC073740-1|AAH73740.1| 388|Homo sapiens progastricsin (pepsinogen
C) protein.
Length = 388
Score = 88.6 bits (210), Expect = 1e-17
Identities = 51/114 (44%), Positives = 70/114 (61%), Gaps = 9/114 (7%)
Frame = +3
Query: 210 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 362
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 363 VISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANG 524
ISIGTPPQ+F V+FDTGSSNLWVPS C + AC H++++ +S++Y NG
Sbjct: 76 EISIGTPPQNFLVLFDTGSSNLWVPSVYCQ--SQACTSHSRFNPSESSTYSTNG 127
>AL365205-1|CAI13181.1| 388|Homo sapiens progastricsin (pepsinogen
C) protein.
Length = 388
Score = 88.6 bits (210), Expect = 1e-17
Identities = 51/114 (44%), Positives = 70/114 (61%), Gaps = 9/114 (7%)
Frame = +3
Query: 210 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 362
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 363 VISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANG 524
ISIGTPPQ+F V+FDTGSSNLWVPS C + AC H++++ +S++Y NG
Sbjct: 76 EISIGTPPQNFLVLFDTGSSNLWVPSVYCQ--SQACTSHSRFNPSESSTYSTNG 127
>M84424-1|AAA52300.1| 396|Homo sapiens cathepsin E protein.
Length = 396
Score = 87.0 bits (206), Expect = 4e-17
Identities = 50/127 (39%), Positives = 73/127 (57%), Gaps = 10/127 (7%)
Frame = +3
Query: 174 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 323
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 324 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKS 503
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC H+++ +S
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQS 125
Query: 504 TSYVANG 524
++Y G
Sbjct: 126 STYSQPG 132
>J05036-1|AAA52130.1| 396|Homo sapiens CTSE protein.
Length = 396
Score = 87.0 bits (206), Expect = 4e-17
Identities = 50/127 (39%), Positives = 73/127 (57%), Gaps = 10/127 (7%)
Frame = +3
Query: 174 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 323
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 324 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKS 503
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC H+++ +S
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQS 125
Query: 504 TSYVANG 524
++Y G
Sbjct: 126 STYSQPG 132
>BX571818-5|CAH73265.1| 363|Homo sapiens cathepsin E protein.
Length = 363
Score = 87.0 bits (206), Expect = 4e-17
Identities = 50/127 (39%), Positives = 73/127 (57%), Gaps = 10/127 (7%)
Frame = +3
Query: 174 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 323
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 324 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKS 503
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC H+++ +S
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQS 125
Query: 504 TSYVANG 524
++Y G
Sbjct: 126 STYSQPG 132
>BX571818-4|CAH73264.1| 396|Homo sapiens cathepsin E protein.
Length = 396
Score = 87.0 bits (206), Expect = 4e-17
Identities = 50/127 (39%), Positives = 73/127 (57%), Gaps = 10/127 (7%)
Frame = +3
Query: 174 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 323
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 324 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKS 503
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC H+++ +S
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQS 125
Query: 504 TSYVANG 524
++Y G
Sbjct: 126 STYSQPG 132
>BC042537-1|AAH42537.1| 396|Homo sapiens cathepsin E protein.
Length = 396
Score = 87.0 bits (206), Expect = 4e-17
Identities = 50/127 (39%), Positives = 73/127 (57%), Gaps = 10/127 (7%)
Frame = +3
Query: 174 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 323
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 324 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKS 503
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC H+++ +S
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQS 125
Query: 504 TSYVANG 524
++Y G
Sbjct: 126 STYSQPG 132
>AJ250717-1|CAB82850.1| 396|Homo sapiens procathepsin E protein.
Length = 396
Score = 87.0 bits (206), Expect = 4e-17
Identities = 50/127 (39%), Positives = 73/127 (57%), Gaps = 10/127 (7%)
Frame = +3
Query: 174 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 323
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 324 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKS 503
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC H+++ +S
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQS 125
Query: 504 TSYVANG 524
++Y G
Sbjct: 126 STYSQPG 132
>AJ250716-1|CAB82849.1| 363|Homo sapiens cathepsin E, alternative
protein.
Length = 363
Score = 87.0 bits (206), Expect = 4e-17
Identities = 50/127 (39%), Positives = 73/127 (57%), Gaps = 10/127 (7%)
Frame = +3
Query: 174 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 323
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 324 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKS 503
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC H+++ +S
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQS 125
Query: 504 TSYVANG 524
++Y G
Sbjct: 126 STYSQPG 132
>BC042578-1|AAH42578.1| 104|Homo sapiens PGC protein protein.
Length = 104
Score = 60.1 bits (139), Expect = 5e-09
Identities = 38/82 (46%), Positives = 49/82 (59%), Gaps = 9/82 (10%)
Frame = +3
Query: 210 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 362
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 363 VISIGTPPQSFKVVFDTGSSNL 428
ISIGTPPQ+F V+FDTGSS L
Sbjct: 76 EISIGTPPQNFLVLFDTGSSPL 97
>X00063-1|CAA24937.1| 300|Homo sapiens protein ( Human kidney mRNA
fragment for renin (aa 105-401). ).
Length = 300
Score = 45.2 bits (102), Expect = 1e-04
Identities = 18/37 (48%), Positives = 24/37 (64%)
Frame = +3
Query: 420 SNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQ 530
SN+WVPS KC AC+ H +D+ S+SY NGT+
Sbjct: 1 SNVWVPSSKCSRLYTACVYHKLFDASDSSSYKHNGTE 37
>AL365205-3|CAM16152.1| 86|Homo sapiens progastricsin (pepsinogen
C) protein.
Length = 86
Score = 38.7 bits (86), Expect = 0.013
Identities = 28/70 (40%), Positives = 37/70 (52%), Gaps = 9/70 (12%)
Frame = +3
Query: 201 SVMALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQ 353
+V+ RVPL + K+ R E G E LR KYD + EP++ Y+DA
Sbjct: 18 AVICKQRVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAA 76
Query: 354 YYGVISIGTP 383
Y+G ISIGTP
Sbjct: 77 YFGEISIGTP 86
>BC014453-1|AAH14453.1| 518|Homo sapiens beta-site APP-cleaving
enzyme 2 protein.
Length = 518
Score = 37.9 bits (84), Expect = 0.022
Identities = 20/57 (35%), Positives = 31/57 (54%)
Frame = +3
Query: 354 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANG 524
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S++Y + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKG 142
>AY358927-1|AAQ89286.1| 518|Homo sapiens BACE2 protein.
Length = 518
Score = 37.9 bits (84), Expect = 0.022
Identities = 20/57 (35%), Positives = 31/57 (54%)
Frame = +3
Query: 354 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANG 524
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S++Y + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKG 142
>AF212252-1|AAG41783.1| 439|Homo sapiens CDA13 protein.
Length = 439
Score = 37.9 bits (84), Expect = 0.022
Identities = 20/57 (35%), Positives = 31/57 (54%)
Frame = +3
Query: 354 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANG 524
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S++Y + G
Sbjct: 13 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKG 63
>AF204944-1|AAF26368.1| 518|Homo sapiens transmembrane aspartic
proteinase Asp 1 protein.
Length = 518
Score = 37.9 bits (84), Expect = 0.022
Identities = 20/57 (35%), Positives = 31/57 (54%)
Frame = +3
Query: 354 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANG 524
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S++Y + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKG 142
>AF200342-1|AAF17078.1| 518|Homo sapiens aspartyl protease 1
protein.
Length = 518
Score = 37.9 bits (84), Expect = 0.022
Identities = 20/57 (35%), Positives = 31/57 (54%)
Frame = +3
Query: 354 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANG 524
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S++Y + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKG 142
>AF200192-1|AAF13714.1| 518|Homo sapiens memapsin 1 protein.
Length = 518
Score = 37.9 bits (84), Expect = 0.022
Identities = 20/57 (35%), Positives = 31/57 (54%)
Frame = +3
Query: 354 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANG 524
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S++Y + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKG 142
>AF188277-1|AAF35836.1| 396|Homo sapiens aspartyl protease protein.
Length = 396
Score = 37.9 bits (84), Expect = 0.022
Identities = 20/57 (35%), Positives = 31/57 (54%)
Frame = +3
Query: 354 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANG 524
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S++Y + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKG 142
>AF188276-1|AAF35835.1| 468|Homo sapiens aspartyl protease protein.
Length = 468
Score = 37.9 bits (84), Expect = 0.022
Identities = 20/57 (35%), Positives = 31/57 (54%)
Frame = +3
Query: 354 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANG 524
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S++Y + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKG 142
>AF178532-1|AAF29494.1| 518|Homo sapiens aspartyl protease protein.
Length = 518
Score = 37.9 bits (84), Expect = 0.022
Identities = 20/57 (35%), Positives = 31/57 (54%)
Frame = +3
Query: 354 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANG 524
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S++Y + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKG 142
>AF117892-1|AAD45240.1| 518|Homo sapiens aspartic-like protease
protein.
Length = 518
Score = 37.9 bits (84), Expect = 0.022
Identities = 20/57 (35%), Positives = 31/57 (54%)
Frame = +3
Query: 354 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANG 524
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S++Y + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKG 142
>AF050171-1|AAD45963.1| 518|Homo sapiens aspartyl protease protein.
Length = 518
Score = 37.9 bits (84), Expect = 0.022
Identities = 20/57 (35%), Positives = 31/57 (54%)
Frame = +3
Query: 354 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANG 524
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S++Y + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKG 142
>DQ007053-1|AAY16982.1| 501|Homo sapiens beta-site APP-cleaving
enzyme 1 protein.
Length = 501
Score = 35.5 bits (78), Expect = 0.12
Identities = 18/53 (33%), Positives = 30/53 (56%)
Frame = +3
Query: 354 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSY 512
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S++Y
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTY 121
>BC065492-1|AAH65492.1| 501|Homo sapiens beta-site APP-cleaving
enzyme 1 protein.
Length = 501
Score = 35.5 bits (78), Expect = 0.12
Identities = 18/53 (33%), Positives = 30/53 (56%)
Frame = +3
Query: 354 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSY 512
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S++Y
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTY 121
>AF338817-1|AAK38375.1| 457|Homo sapiens beta-site APP cleaving
enzyme type C protein.
Length = 457
Score = 35.5 bits (78), Expect = 0.12
Identities = 18/53 (33%), Positives = 30/53 (56%)
Frame = +3
Query: 354 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSY 512
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S++Y
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTY 121
>AF338816-1|AAK38374.1| 476|Homo sapiens beta-site APP cleaving
enzyme type B protein.
Length = 476
Score = 35.5 bits (78), Expect = 0.12
Identities = 18/53 (33%), Positives = 30/53 (56%)
Frame = +3
Query: 354 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSY 512
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S++Y
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTY 121
>AF204943-1|AAF26367.1| 501|Homo sapiens transmembrane aspartic
proteinase Asp 2 protein.
Length = 501
Score = 35.5 bits (78), Expect = 0.12
Identities = 18/53 (33%), Positives = 30/53 (56%)
Frame = +3
Query: 354 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSY 512
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S++Y
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTY 121
>AF201468-1|AAF18982.1| 501|Homo sapiens APP beta-secretase
protein.
Length = 501
Score = 35.5 bits (78), Expect = 0.12
Identities = 18/53 (33%), Positives = 30/53 (56%)
Frame = +3
Query: 354 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSY 512
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S++Y
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTY 121
>AF200343-1|AAF17079.1| 501|Homo sapiens aspartyl protease 2
protein.
Length = 501
Score = 35.5 bits (78), Expect = 0.12
Identities = 18/53 (33%), Positives = 30/53 (56%)
Frame = +3
Query: 354 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSY 512
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S++Y
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTY 121
>AF200193-1|AAF13715.1| 488|Homo sapiens memapsin 2 protein.
Length = 488
Score = 35.5 bits (78), Expect = 0.12
Identities = 18/53 (33%), Positives = 30/53 (56%)
Frame = +3
Query: 354 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSY 512
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S++Y
Sbjct: 62 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTY 108
>AF190725-1|AAF04142.1| 501|Homo sapiens beta-site APP cleaving
enzyme protein.
Length = 501
Score = 35.5 bits (78), Expect = 0.12
Identities = 18/53 (33%), Positives = 30/53 (56%)
Frame = +3
Query: 354 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSY 512
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S++Y
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTY 121
>AB089958-1|BAC81826.1| 127|Homo sapiens beta-site APP cleaving
enzyme isoform I-127 protein.
Length = 127
Score = 35.5 bits (78), Expect = 0.12
Identities = 18/53 (33%), Positives = 30/53 (56%)
Frame = +3
Query: 354 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSY 512
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S++Y
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTY 121
>AB050438-1|BAB40933.1| 432|Homo sapiens beta-site APP cleaving
enzyme I-432 protein.
Length = 432
Score = 35.5 bits (78), Expect = 0.12
Identities = 18/53 (33%), Positives = 30/53 (56%)
Frame = +3
Query: 354 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSY 512
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S++Y
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTY 121
>AB050437-1|BAB40932.1| 457|Homo sapiens beta-site APP cleaving
enzyme I-457 protein.
Length = 457
Score = 35.5 bits (78), Expect = 0.12
Identities = 18/53 (33%), Positives = 30/53 (56%)
Frame = +3
Query: 354 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSY 512
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S++Y
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTY 121
>AB050436-1|BAB40931.1| 476|Homo sapiens beta-site APP cleaving
enzyme I-476 protein.
Length = 476
Score = 35.5 bits (78), Expect = 0.12
Identities = 18/53 (33%), Positives = 30/53 (56%)
Frame = +3
Query: 354 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSY 512
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S++Y
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTY 121
>AB032975-1|BAA86463.2| 532|Homo sapiens KIAA1149 protein protein.
Length = 532
Score = 35.5 bits (78), Expect = 0.12
Identities = 18/53 (33%), Positives = 30/53 (56%)
Frame = +3
Query: 354 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSY 512
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S++Y
Sbjct: 106 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTY 152
>AK075539-1|BAC11682.1| 423|Homo sapiens protein ( Homo sapiens
cDNA PSEC0239 fis, clone OVARC1000363, highly similar to
Homo sapiens aspartyl protease mRNA. ).
Length = 423
Score = 35.1 bits (77), Expect = 0.16
Identities = 18/51 (35%), Positives = 28/51 (54%)
Frame = +3
Query: 372 IGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANG 524
IGTPPQ +++ DTGSSN V Y + +D+ +S++Y + G
Sbjct: 3 IGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKG 47
>BC036084-1|AAH36084.1| 501|Homo sapiens beta-site APP-cleaving
enzyme 1 protein.
Length = 501
Score = 34.7 bits (76), Expect = 0.21
Identities = 13/27 (48%), Positives = 20/27 (74%)
Frame = +3
Query: 354 YYGVISIGTPPQSFKVVFDTGSSNLWV 434
YY +++G+PPQ+ ++ DTGSSN V
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAV 101
>BC030606-1|AAH30606.2| 514|Homo sapiens coiled-coil domain
containing 11 protein.
Length = 514
Score = 30.7 bits (66), Expect = 3.3
Identities = 12/26 (46%), Positives = 18/26 (69%)
Frame = -3
Query: 419 GSGVEYHLERLRRRADTDHSVVLSIK 342
G G E+HLER+RR ++++ SIK
Sbjct: 30 GQGAEHHLERIRRSHQKHNAILASIK 55
>BC047091-1|AAH47091.1| 458|Homo sapiens zinc finger protein 19
protein.
Length = 458
Score = 29.5 bits (63), Expect = 7.7
Identities = 14/39 (35%), Positives = 21/39 (53%)
Frame = -2
Query: 351 EHQDNLTMVRVKGQSHRILISTAPVQCQPHESGFSQFSY 235
+HQD T+ ++G+ RI + P C+ FS FSY
Sbjct: 137 KHQDIPTVKNIQGKVPRIPCARKPFICEECGKSFSYFSY 175
>AL834237-1|CAD38915.1| 339|Homo sapiens hypothetical protein
protein.
Length = 339
Score = 29.5 bits (63), Expect = 7.7
Identities = 14/39 (35%), Positives = 21/39 (53%)
Frame = -2
Query: 351 EHQDNLTMVRVKGQSHRILISTAPVQCQPHESGFSQFSY 235
+HQD T+ ++G+ RI + P C+ FS FSY
Sbjct: 18 KHQDIPTVKNIQGKVPRIPCARKPFICEECGKSFSYFSY 56
>AK057330-1|BAB71430.1| 446|Homo sapiens protein ( Homo sapiens
cDNA FLJ32768 fis, clone TESTI2001879, weakly similar to
ZINC FINGER PROTEIN 157. ).
Length = 446
Score = 29.5 bits (63), Expect = 7.7
Identities = 14/39 (35%), Positives = 21/39 (53%)
Frame = -2
Query: 351 EHQDNLTMVRVKGQSHRILISTAPVQCQPHESGFSQFSY 235
+HQD T+ ++G+ RI + P C+ FS FSY
Sbjct: 125 KHQDIPTVKNIQGKVPRIPCARKPFICEECGKSFSYFSY 163
>AK055567-1|BAB70957.1| 446|Homo sapiens protein ( Homo sapiens
cDNA FLJ31005 fis, clone HLUNG2000068, weakly similar to
ZINC FINGER PROTEIN 157. ).
Length = 446
Score = 29.5 bits (63), Expect = 7.7
Identities = 14/39 (35%), Positives = 21/39 (53%)
Frame = -2
Query: 351 EHQDNLTMVRVKGQSHRILISTAPVQCQPHESGFSQFSY 235
+HQD T+ ++G+ RI + P C+ FS FSY
Sbjct: 125 KHQDIPTVKNIQGKVPRIPCARKPFICEECGKSFSYFSY 163
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 73,391,530
Number of Sequences: 237096
Number of extensions: 1548907
Number of successful extensions: 2788
Number of sequences better than 10.0: 73
Number of HSP's better than 10.0 without gapping: 2723
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2768
length of database: 76,859,062
effective HSP length: 85
effective length of database: 56,705,902
effective search space used: 5160237082
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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