Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= bmnc23h22
(705 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
CR456743-1|CAG33024.1| 538|Homo sapiens KPNA1 protein. 222 8e-58
BT006959-1|AAP35605.1| 538|Homo sapiens karyopherin alpha 1 (im... 222 8e-58
BC003009-1|AAH03009.1| 538|Homo sapiens karyopherin alpha 1 (im... 222 8e-58
BC002374-1|AAH02374.1| 538|Homo sapiens karyopherin alpha 1 (im... 222 8e-58
BC047409-1|AAH47409.1| 539|Homo sapiens karyopherin alpha 5 (im... 220 5e-57
AL132795-5|CAI20500.1| 539|Homo sapiens karyopherin alpha 5 (im... 220 5e-57
AF005361-1|AAC51868.1| 536|Homo sapiens importin alpha 6 protein. 219 6e-57
BC090864-1|AAH90864.1| 538|Homo sapiens karyopherin alpha 1 (im... 218 2e-56
S75295-1|AAC60648.1| 538|Homo sapiens nucleoprotein interactor ... 217 3e-56
BT009843-1|AAP88845.1| 536|Homo sapiens karyopherin alpha 6 (im... 212 1e-54
BC020520-1|AAH20520.1| 536|Homo sapiens karyopherin alpha 6 (im... 212 1e-54
AL445248-5|CAH71948.1| 536|Homo sapiens karyopherin alpha 6 (im... 212 1e-54
AL049795-3|CAI22056.1| 536|Homo sapiens karyopherin alpha 6 (im... 212 1e-54
AF060543-1|AAC15233.1| 536|Homo sapiens importin alpha 7 subuni... 212 1e-54
BT006665-1|AAP35311.1| 529|Homo sapiens karyopherin alpha 2 (RA... 182 1e-45
BC005978-1|AAH05978.1| 529|Homo sapiens karyopherin alpha 2 (RA... 182 1e-45
U28386-1|AAA69957.1| 529|Homo sapiens hSRP1alpha protein. 180 4e-45
U09559-1|AAA65700.1| 529|Homo sapiens Rch1 protein. 180 4e-45
BC053343-1|AAH53343.1| 529|Homo sapiens karyopherin alpha 2 (RA... 180 4e-45
AJ303086-1|CAC83080.1| 529|Homo sapiens karyopherin alpha 2 pro... 180 4e-45
BC067848-1|AAH67848.1| 529|Homo sapiens karyopherin alpha 2 (RA... 178 1e-44
D89618-1|BAA20378.1| 521|Homo sapiens karyopherin alhph 3 protein. 172 9e-43
BC024202-1|AAH24202.1| 521|Homo sapiens karyopherin alpha 3 (im... 172 1e-42
BC017355-1|AAH17355.1| 521|Homo sapiens karyopherin alpha 3 (im... 172 1e-42
AL136301-1|CAH71145.1| 521|Homo sapiens karyopherin alpha 3 (im... 172 1e-42
AL135901-3|CAI40716.1| 521|Homo sapiens karyopherin alpha 3 (im... 172 1e-42
AK223480-1|BAD97200.1| 521|Homo sapiens karyopherin alpha 3 var... 172 1e-42
AF005263-1|AAQ13404.1| 521|Homo sapiens importin alpha-3 subuni... 172 1e-42
Y12394-1|CAA73026.1| 521|Homo sapiens SRP1-like protein protein. 171 3e-42
BC035090-1|AAH35090.1| 521|Homo sapiens karyopherin alpha 3 (im... 171 3e-42
AF034756-1|AAB87693.1| 521|Homo sapiens importin-alpha homolog ... 169 8e-42
U93240-1|AAC25605.1| 521|Homo sapiens importin alpha 3 protein. 166 8e-41
BC034493-1|AAH34493.1| 521|Homo sapiens karyopherin alpha 4 (im... 166 8e-41
BC028691-1|AAH28691.1| 521|Homo sapiens karyopherin alpha 4 (im... 166 8e-41
AB002533-1|BAA19546.1| 521|Homo sapiens Qip1 protein. 166 8e-41
AL132795-6|CAI20501.1| 142|Homo sapiens karyopherin alpha 5 (im... 135 2e-31
AL049795-1|CAI22054.1| 321|Homo sapiens karyopherin alpha 6 (im... 97 5e-20
Y12393-1|CAA73025.1| 281|Homo sapiens SRP1-like protein protein. 44 4e-04
BC030585-1|AAH30585.1| 458|Homo sapiens sperm associated antige... 43 0.001
AL513128-4|CAH72210.1| 509|Homo sapiens sperm associated antige... 43 0.001
AL513128-3|CAH72209.1| 458|Homo sapiens sperm associated antige... 43 0.001
AL158211-15|CAI15963.1| 509|Homo sapiens sperm associated antig... 43 0.001
AL158211-14|CAI15962.1| 458|Homo sapiens sperm associated antig... 43 0.001
AF079363-1|AAC32590.1| 509|Homo sapiens sperm flagellar protein... 43 0.001
CR533552-1|CAG38583.1| 509|Homo sapiens SPAG6 protein. 42 0.002
AL513128-1|CAH72207.1| 246|Homo sapiens sperm associated antige... 42 0.003
AL158211-12|CAI15960.1| 246|Homo sapiens sperm associated antig... 42 0.003
BC041699-1|AAH41699.1| 659|Homo sapiens armadillo repeat contai... 41 0.005
BC032661-1|AAH32661.1| 659|Homo sapiens armadillo repeat contai... 41 0.005
AL096748-1|CAB46423.1| 242|Homo sapiens hypothetical protein pr... 40 0.007
AK001882-1|BAA91959.1| 431|Homo sapiens protein ( Homo sapiens ... 39 0.020
AK223275-1|BAD96995.1| 1181|Homo sapiens AT rich interactive dom... 36 0.14
X63465-1|CAA45067.1| 558|Homo sapiens smg GDS protein. 35 0.33
BC099845-1|AAH99845.1| 559|Homo sapiens RAP1GDS1 protein protein. 35 0.33
BC099708-1|AAH99708.1| 558|Homo sapiens RAP1GDS1 protein protein. 35 0.33
BC098334-1|AAH98334.1| 558|Homo sapiens RAP1GDS1 protein protein. 35 0.33
BC112895-1|AAI12896.1| 164|Homo sapiens ARID1A protein protein. 34 0.57
AL512408-3|CAI23484.1| 2285|Homo sapiens AT rich interactive dom... 34 0.57
AL512408-1|CAI23482.1| 1685|Homo sapiens AT rich interactive dom... 34 0.57
AL034380-9|CAI21623.1| 2285|Homo sapiens AT rich interactive dom... 34 0.57
AL034380-6|CAI21621.1| 1685|Homo sapiens AT rich interactive dom... 34 0.57
AK074940-1|BAC11306.1| 754|Homo sapiens protein ( Homo sapiens ... 34 0.57
AK027655-1|BAB55270.1| 613|Homo sapiens protein ( Homo sapiens ... 34 0.57
AK027467-1|BAB55132.1| 375|Homo sapiens protein ( Homo sapiens ... 34 0.57
AK027442-1|BAB55114.1| 527|Homo sapiens protein ( Homo sapiens ... 34 0.57
AF521670-1|AAN03446.1| 1999|Homo sapiens SWI/SNF chromatin remod... 34 0.57
AF265208-1|AAF75765.1| 1927|Homo sapiens SWI-SNF complex protein... 34 0.57
AF231056-1|AAG33967.1| 2285|Homo sapiens BRG1-Associated Factor ... 34 0.57
AF219114-1|AAG17549.2| 1939|Homo sapiens chromatin remodelling f... 34 0.57
AF268913-1|AAK54505.1| 1685|Homo sapiens OSA1 nuclear protein pr... 32 1.7
L09190-1|AAA65582.1| 1898|Homo sapiens trichohyalin protein. 31 4.0
AL589986-1|CAH70024.1| 1943|Homo sapiens trichohyalin protein. 31 4.0
AM156947-1|CAJ42307.1| 1221|Homo sapiens centrosome and spindle ... 31 5.3
AJ583433-1|CAE47426.1| 876|Homo sapiens centrosome spindle pole... 31 5.3
BC039312-1|AAH39312.1| 872|Homo sapiens armadillo repeat contai... 30 7.0
AY436643-1|AAR99738.1| 688|Homo sapiens beta-catenin-like prote... 30 7.0
AL139815-2|CAH72189.1| 875|Homo sapiens novel protein protein. 30 7.0
AL139815-1|CAH72188.1| 546|Homo sapiens novel protein protein. 30 7.0
AK057389-1|BAB71463.1| 669|Homo sapiens protein ( Homo sapiens ... 30 7.0
>CR456743-1|CAG33024.1| 538|Homo sapiens KPNA1 protein.
Length = 538
Score = 222 bits (543), Expect = 8e-58
Identities = 117/203 (57%), Positives = 142/203 (69%), Gaps = 10/203 (4%)
Frame = +3
Query: 114 YKNVGLSADELRRRREEEGVQLRKQKREQQLFKRRNVNLPGTNAA------GAASQEDIN 275
YKN L+ DE+RRRREEEG+QLRKQKRE+QLFKRRNV G + IN
Sbjct: 14 YKNKSLNPDEMRRRREEEGLQLRKQKREEQLFKRRNVATAEEETEEEVMSDGGFHEAQIN 73
Query: 276 ---ISPSDCITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQS-GIVPKFIE 443
++P IT DM+ ++ +PE+Q+ ATQKFRKLLSKEPNPPID VI + G+V +F+E
Sbjct: 74 NMEMAPGGVITSDMIEMIFSKSPEQQLSATQKFRKLLSKEPNPPIDEVISTPGVVARFVE 133
Query: 444 FLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWAL 623
FL +N TLQFE+AW LTNIASG+S QTRIV+ GAV + + LLS E+V EQAVWAL
Sbjct: 134 FLKRKENCTLQFESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFEDVQEQAVWAL 193
Query: 624 GNIAGDSPYCRDIVLAAGVSPTL 692
GNIAGDS CRD VL + P L
Sbjct: 194 GNIAGDSTMCRDYVLDCNILPPL 216
Score = 58.8 bits (136), Expect = 2e-08
Identities = 49/169 (28%), Positives = 81/169 (47%), Gaps = 5/169 (2%)
Frame = +3
Query: 201 QLFKRRNVNLPGTNAAGAASQEDINISPSD---CITPDM-VLAVYLDNPEEQVIATQKFR 368
QLF ++N NA A S SP ++P + VL+ L + V+A +
Sbjct: 218 QLFSKQNRLTMTRNAVWALSNLCRGKSPPPEFAKVSPCLNVLSWLLFVSDTDVLADACWA 277
Query: 369 -KLLSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVD 545
LS PN I AVI +G+ + +E L H + + A A+ NI +G QT+++++
Sbjct: 278 LSYLSDGPNDKIQAVIDAGVCRRLVELLM-HNDYKVVSPALRAVGNIVTGDDIQTQVILN 336
Query: 546 YGAVNVLVGLLSGSTENVCEQAVWALGNIAGDSPYCRDIVLAAGVSPTL 692
A+ L+ LLS E++ ++A W + NI + V+ A + P L
Sbjct: 337 CSALQSLLHLLSSPKESIKKEACWTISNITAGNRAQIQTVIDANIFPAL 385
Score = 48.4 bits (110), Expect = 2e-05
Identities = 33/82 (40%), Positives = 44/82 (53%), Gaps = 2/82 (2%)
Frame = +3
Query: 408 VIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGS 587
VIQ+G VP FIE L++ +Q +A WAL NIA S+ V+D + L+ L S
Sbjct: 165 VIQAGAVPIFIELLSSEFED-VQEQAVWALGNIAGDSTMCRDYVLDCNILPPLLQLFSKQ 223
Query: 588 TE-NVCEQAVWALGNIA-GDSP 647
+ AVWAL N+ G SP
Sbjct: 224 NRLTMTRNAVWALSNLCRGKSP 245
Score = 44.4 bits (100), Expect = 4e-04
Identities = 29/94 (30%), Positives = 43/94 (45%), Gaps = 1/94 (1%)
Frame = +3
Query: 402 DAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLS 581
D V+ I+P ++ + T+ A WAL+N+ G S +NVL LL
Sbjct: 205 DYVLDCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKSPPPEFAKVSPCLNVLSWLLF 264
Query: 582 GSTENVCEQAVWALGNIAGDSPYCR-DIVLAAGV 680
S +V A WAL ++ D P + V+ AGV
Sbjct: 265 VSDTDVLADACWALSYLS-DGPNDKIQAVIDAGV 297
Score = 43.6 bits (98), Expect = 7e-04
Identities = 28/79 (35%), Positives = 40/79 (50%), Gaps = 1/79 (1%)
Frame = +3
Query: 399 IDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSG-QTRIVVDYGAVNVLVGL 575
I VI + I P I L + T + EAAWA+TN SG S Q + +V+ G + L L
Sbjct: 373 IQTVIDANIFPALISILQTAEFRTRK-EAAWAITNATSGGSAEQIKYLVELGCIKPLCDL 431
Query: 576 LSGSTENVCEQAVWALGNI 632
L+ + + A+ L NI
Sbjct: 432 LTVMDSKIVQVALNGLENI 450
Score = 39.5 bits (88), Expect = 0.011
Identities = 17/74 (22%), Positives = 38/74 (51%)
Frame = +3
Query: 408 VIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGS 587
++ + + L++ K +++ EA W ++NI +G+ Q + V+D L+ +L +
Sbjct: 334 ILNCSALQSLLHLLSSPKE-SIKKEACWTISNITAGNRAQIQTVIDANIFPALISILQTA 392
Query: 588 TENVCEQAVWALGN 629
++A WA+ N
Sbjct: 393 EFRTRKEAAWAITN 406
>BT006959-1|AAP35605.1| 538|Homo sapiens karyopherin alpha 1
(importin alpha 5) protein.
Length = 538
Score = 222 bits (543), Expect = 8e-58
Identities = 117/203 (57%), Positives = 142/203 (69%), Gaps = 10/203 (4%)
Frame = +3
Query: 114 YKNVGLSADELRRRREEEGVQLRKQKREQQLFKRRNVNLPGTNAA------GAASQEDIN 275
YKN L+ DE+RRRREEEG+QLRKQKRE+QLFKRRNV G + IN
Sbjct: 14 YKNKSLNPDEMRRRREEEGLQLRKQKREEQLFKRRNVATAEEETEEEVMSDGGFHEAQIN 73
Query: 276 ---ISPSDCITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQS-GIVPKFIE 443
++P IT DM+ ++ +PE+Q+ ATQKFRKLLSKEPNPPID VI + G+V +F+E
Sbjct: 74 NMEMAPGGVITSDMIEMIFSKSPEQQLSATQKFRKLLSKEPNPPIDEVISTPGVVARFVE 133
Query: 444 FLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWAL 623
FL +N TLQFE+AW LTNIASG+S QTRIV+ GAV + + LLS E+V EQAVWAL
Sbjct: 134 FLKRKENCTLQFESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFEDVQEQAVWAL 193
Query: 624 GNIAGDSPYCRDIVLAAGVSPTL 692
GNIAGDS CRD VL + P L
Sbjct: 194 GNIAGDSTMCRDYVLDCNILPPL 216
Score = 58.8 bits (136), Expect = 2e-08
Identities = 49/169 (28%), Positives = 81/169 (47%), Gaps = 5/169 (2%)
Frame = +3
Query: 201 QLFKRRNVNLPGTNAAGAASQEDINISPSD---CITPDM-VLAVYLDNPEEQVIATQKFR 368
QLF ++N NA A S SP ++P + VL+ L + V+A +
Sbjct: 218 QLFSKQNRLTMTRNAVWALSNLCRGKSPPPEFAKVSPCLNVLSWLLFVSDTDVLADACWA 277
Query: 369 -KLLSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVD 545
LS PN I AVI +G+ + +E L H + + A A+ NI +G QT+++++
Sbjct: 278 LSYLSDGPNDKIQAVIDAGVCRRLVELLM-HNDYKVVSPALRAVGNIVTGDDIQTQVILN 336
Query: 546 YGAVNVLVGLLSGSTENVCEQAVWALGNIAGDSPYCRDIVLAAGVSPTL 692
A+ L+ LLS E++ ++A W + NI + V+ A + P L
Sbjct: 337 CSALQSLLHLLSSPKESIKKEACWTISNITAGNRAQIQTVIDANIFPAL 385
Score = 48.4 bits (110), Expect = 2e-05
Identities = 33/82 (40%), Positives = 44/82 (53%), Gaps = 2/82 (2%)
Frame = +3
Query: 408 VIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGS 587
VIQ+G VP FIE L++ +Q +A WAL NIA S+ V+D + L+ L S
Sbjct: 165 VIQAGAVPIFIELLSSEFED-VQEQAVWALGNIAGDSTMCRDYVLDCNILPPLLQLFSKQ 223
Query: 588 TE-NVCEQAVWALGNIA-GDSP 647
+ AVWAL N+ G SP
Sbjct: 224 NRLTMTRNAVWALSNLCRGKSP 245
Score = 44.4 bits (100), Expect = 4e-04
Identities = 29/94 (30%), Positives = 43/94 (45%), Gaps = 1/94 (1%)
Frame = +3
Query: 402 DAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLS 581
D V+ I+P ++ + T+ A WAL+N+ G S +NVL LL
Sbjct: 205 DYVLDCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKSPPPEFAKVSPCLNVLSWLLF 264
Query: 582 GSTENVCEQAVWALGNIAGDSPYCR-DIVLAAGV 680
S +V A WAL ++ D P + V+ AGV
Sbjct: 265 VSDTDVLADACWALSYLS-DGPNDKIQAVIDAGV 297
Score = 43.6 bits (98), Expect = 7e-04
Identities = 28/79 (35%), Positives = 40/79 (50%), Gaps = 1/79 (1%)
Frame = +3
Query: 399 IDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSG-QTRIVVDYGAVNVLVGL 575
I VI + I P I L + T + EAAWA+TN SG S Q + +V+ G + L L
Sbjct: 373 IQTVIDANIFPALISILQTAEFRTRK-EAAWAITNATSGGSAEQIKYLVELGCIKPLCDL 431
Query: 576 LSGSTENVCEQAVWALGNI 632
L+ + + A+ L NI
Sbjct: 432 LTVMDSKIVQVALNGLENI 450
Score = 39.5 bits (88), Expect = 0.011
Identities = 17/74 (22%), Positives = 38/74 (51%)
Frame = +3
Query: 408 VIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGS 587
++ + + L++ K +++ EA W ++NI +G+ Q + V+D L+ +L +
Sbjct: 334 ILNCSALQSLLHLLSSPKE-SIKKEACWTISNITAGNRAQIQTVIDANIFPALISILQTA 392
Query: 588 TENVCEQAVWALGN 629
++A WA+ N
Sbjct: 393 EFRTRKEAAWAITN 406
>BC003009-1|AAH03009.1| 538|Homo sapiens karyopherin alpha 1
(importin alpha 5) protein.
Length = 538
Score = 222 bits (543), Expect = 8e-58
Identities = 117/203 (57%), Positives = 142/203 (69%), Gaps = 10/203 (4%)
Frame = +3
Query: 114 YKNVGLSADELRRRREEEGVQLRKQKREQQLFKRRNVNLPGTNAA------GAASQEDIN 275
YKN L+ DE+RRRREEEG+QLRKQKRE+QLFKRRNV G + IN
Sbjct: 14 YKNKSLNPDEMRRRREEEGLQLRKQKREEQLFKRRNVATAEEETEEEVMSDGGFHEAQIN 73
Query: 276 ---ISPSDCITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQS-GIVPKFIE 443
++P IT DM+ ++ +PE+Q+ ATQKFRKLLSKEPNPPID VI + G+V +F+E
Sbjct: 74 NMEMAPGGVITSDMIEMIFSKSPEQQLSATQKFRKLLSKEPNPPIDEVISTPGVVARFVE 133
Query: 444 FLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWAL 623
FL +N TLQFE+AW LTNIASG+S QTRIV+ GAV + + LLS E+V EQAVWAL
Sbjct: 134 FLKRKENCTLQFESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFEDVQEQAVWAL 193
Query: 624 GNIAGDSPYCRDIVLAAGVSPTL 692
GNIAGDS CRD VL + P L
Sbjct: 194 GNIAGDSTMCRDYVLDCNILPPL 216
Score = 58.8 bits (136), Expect = 2e-08
Identities = 49/169 (28%), Positives = 81/169 (47%), Gaps = 5/169 (2%)
Frame = +3
Query: 201 QLFKRRNVNLPGTNAAGAASQEDINISPSD---CITPDM-VLAVYLDNPEEQVIATQKFR 368
QLF ++N NA A S SP ++P + VL+ L + V+A +
Sbjct: 218 QLFSKQNRLTMTRNAVWALSNLCRGKSPPPEFAKVSPCLNVLSWLLFVSDTDVLADACWA 277
Query: 369 -KLLSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVD 545
LS PN I AVI +G+ + +E L H + + A A+ NI +G QT+++++
Sbjct: 278 LSYLSDGPNDKIQAVIDAGVCRRLVELLM-HNDYKVVSPALRAVGNIVTGDDIQTQVILN 336
Query: 546 YGAVNVLVGLLSGSTENVCEQAVWALGNIAGDSPYCRDIVLAAGVSPTL 692
A+ L+ LLS E++ ++A W + NI + V+ A + P L
Sbjct: 337 CSALQSLLHLLSSPKESIKKEACWTISNITAGNRAQIQTVIDANIFPAL 385
Score = 48.4 bits (110), Expect = 2e-05
Identities = 33/82 (40%), Positives = 44/82 (53%), Gaps = 2/82 (2%)
Frame = +3
Query: 408 VIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGS 587
VIQ+G VP FIE L++ +Q +A WAL NIA S+ V+D + L+ L S
Sbjct: 165 VIQAGAVPIFIELLSSEFED-VQEQAVWALGNIAGDSTMCRDYVLDCNILPPLLQLFSKQ 223
Query: 588 TE-NVCEQAVWALGNIA-GDSP 647
+ AVWAL N+ G SP
Sbjct: 224 NRLTMTRNAVWALSNLCRGKSP 245
Score = 44.4 bits (100), Expect = 4e-04
Identities = 29/94 (30%), Positives = 43/94 (45%), Gaps = 1/94 (1%)
Frame = +3
Query: 402 DAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLS 581
D V+ I+P ++ + T+ A WAL+N+ G S +NVL LL
Sbjct: 205 DYVLDCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKSPPPEFAKVSPCLNVLSWLLF 264
Query: 582 GSTENVCEQAVWALGNIAGDSPYCR-DIVLAAGV 680
S +V A WAL ++ D P + V+ AGV
Sbjct: 265 VSDTDVLADACWALSYLS-DGPNDKIQAVIDAGV 297
Score = 43.6 bits (98), Expect = 7e-04
Identities = 28/79 (35%), Positives = 40/79 (50%), Gaps = 1/79 (1%)
Frame = +3
Query: 399 IDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSG-QTRIVVDYGAVNVLVGL 575
I VI + I P I L + T + EAAWA+TN SG S Q + +V+ G + L L
Sbjct: 373 IQTVIDANIFPALISILQTAEFRTRK-EAAWAITNATSGGSAEQIKYLVELGCIKPLCDL 431
Query: 576 LSGSTENVCEQAVWALGNI 632
L+ + + A+ L NI
Sbjct: 432 LTVMDSKIVQVALNGLENI 450
Score = 39.5 bits (88), Expect = 0.011
Identities = 17/74 (22%), Positives = 38/74 (51%)
Frame = +3
Query: 408 VIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGS 587
++ + + L++ K +++ EA W ++NI +G+ Q + V+D L+ +L +
Sbjct: 334 ILNCSALQSLLHLLSSPKE-SIKKEACWTISNITAGNRAQIQTVIDANIFPALISILQTA 392
Query: 588 TENVCEQAVWALGN 629
++A WA+ N
Sbjct: 393 EFRTRKEAAWAITN 406
>BC002374-1|AAH02374.1| 538|Homo sapiens karyopherin alpha 1
(importin alpha 5) protein.
Length = 538
Score = 222 bits (543), Expect = 8e-58
Identities = 117/203 (57%), Positives = 142/203 (69%), Gaps = 10/203 (4%)
Frame = +3
Query: 114 YKNVGLSADELRRRREEEGVQLRKQKREQQLFKRRNVNLPGTNAA------GAASQEDIN 275
YKN L+ DE+RRRREEEG+QLRKQKRE+QLFKRRNV G + IN
Sbjct: 14 YKNKSLNPDEMRRRREEEGLQLRKQKREEQLFKRRNVATAEEETEEEVMSDGGFHEAQIN 73
Query: 276 ---ISPSDCITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQS-GIVPKFIE 443
++P IT DM+ ++ +PE+Q+ ATQKFRKLLSKEPNPPID VI + G+V +F+E
Sbjct: 74 NMEMAPGGVITSDMIEMIFSKSPEQQLSATQKFRKLLSKEPNPPIDEVISTPGVVARFVE 133
Query: 444 FLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWAL 623
FL +N TLQFE+AW LTNIASG+S QTRIV+ GAV + + LLS E+V EQAVWAL
Sbjct: 134 FLKRKENCTLQFESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFEDVQEQAVWAL 193
Query: 624 GNIAGDSPYCRDIVLAAGVSPTL 692
GNIAGDS CRD VL + P L
Sbjct: 194 GNIAGDSTMCRDYVLDCNILPPL 216
Score = 58.8 bits (136), Expect = 2e-08
Identities = 49/169 (28%), Positives = 81/169 (47%), Gaps = 5/169 (2%)
Frame = +3
Query: 201 QLFKRRNVNLPGTNAAGAASQEDINISPSD---CITPDM-VLAVYLDNPEEQVIATQKFR 368
QLF ++N NA A S SP ++P + VL+ L + V+A +
Sbjct: 218 QLFSKQNRLTMTRNAVWALSNLCRGKSPPPEFAKVSPCLNVLSWLLFVSDTDVLADACWA 277
Query: 369 -KLLSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVD 545
LS PN I AVI +G+ + +E L H + + A A+ NI +G QT+++++
Sbjct: 278 LSYLSDGPNDKIQAVIDAGVCRRLVELLM-HNDYKVVSPALRAVGNIVTGDDIQTQVILN 336
Query: 546 YGAVNVLVGLLSGSTENVCEQAVWALGNIAGDSPYCRDIVLAAGVSPTL 692
A+ L+ LLS E++ ++A W + NI + V+ A + P L
Sbjct: 337 CSALQSLLHLLSSPKESIKKEACWTISNITAGNRAQIQTVIDANIFPAL 385
Score = 48.4 bits (110), Expect = 2e-05
Identities = 33/82 (40%), Positives = 44/82 (53%), Gaps = 2/82 (2%)
Frame = +3
Query: 408 VIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGS 587
VIQ+G VP FIE L++ +Q +A WAL NIA S+ V+D + L+ L S
Sbjct: 165 VIQAGAVPIFIELLSSEFED-VQEQAVWALGNIAGDSTMCRDYVLDCNILPPLLQLFSKQ 223
Query: 588 TE-NVCEQAVWALGNIA-GDSP 647
+ AVWAL N+ G SP
Sbjct: 224 NRLTMTRNAVWALSNLCRGKSP 245
Score = 44.4 bits (100), Expect = 4e-04
Identities = 29/94 (30%), Positives = 43/94 (45%), Gaps = 1/94 (1%)
Frame = +3
Query: 402 DAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLS 581
D V+ I+P ++ + T+ A WAL+N+ G S +NVL LL
Sbjct: 205 DYVLDCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKSPPPEFAKVSPCLNVLSWLLF 264
Query: 582 GSTENVCEQAVWALGNIAGDSPYCR-DIVLAAGV 680
S +V A WAL ++ D P + V+ AGV
Sbjct: 265 VSDTDVLADACWALSYLS-DGPNDKIQAVIDAGV 297
Score = 43.6 bits (98), Expect = 7e-04
Identities = 28/79 (35%), Positives = 40/79 (50%), Gaps = 1/79 (1%)
Frame = +3
Query: 399 IDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSG-QTRIVVDYGAVNVLVGL 575
I VI + I P I L + T + EAAWA+TN SG S Q + +V+ G + L L
Sbjct: 373 IQTVIDANIFPALISILQTAEFRTRK-EAAWAITNATSGGSAEQIKYLVELGCIKPLCDL 431
Query: 576 LSGSTENVCEQAVWALGNI 632
L+ + + A+ L NI
Sbjct: 432 LTVMDSKIVQVALNGLENI 450
Score = 39.5 bits (88), Expect = 0.011
Identities = 17/74 (22%), Positives = 38/74 (51%)
Frame = +3
Query: 408 VIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGS 587
++ + + L++ K +++ EA W ++NI +G+ Q + V+D L+ +L +
Sbjct: 334 ILNCSALQSLLHLLSSPKE-SIKKEACWTISNITAGNRAQIQTVIDANIFPALISILQTA 392
Query: 588 TENVCEQAVWALGN 629
++A WA+ N
Sbjct: 393 EFRTRKEAAWAITN 406
>BC047409-1|AAH47409.1| 539|Homo sapiens karyopherin alpha 5
(importin alpha 6) protein.
Length = 539
Score = 220 bits (537), Expect = 5e-57
Identities = 113/201 (56%), Positives = 147/201 (73%), Gaps = 8/201 (3%)
Frame = +3
Query: 114 YKNVGLSADELRRRREEEGVQLRKQKREQQLFKRRNVNLPGTNAAGAASQ-EDINISPS- 287
YKN L+ E+RRRREEEG+QLRKQKRE+QLFKRRNV LP + + S +D +IS +
Sbjct: 17 YKNKALNPQEMRRRREEEGIQLRKQKREEQLFKRRNVYLPRNDESMLESPIQDPDISSTV 76
Query: 288 -----DCITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQS-GIVPKFIEFL 449
+ +T DMV ++ +N ++Q+ ATQKFRKLLSKEPNPPID VIQ G+V +F++FL
Sbjct: 77 PIPEEEVVTTDMVQMIFSNNADQQLTATQKFRKLLSKEPNPPIDQVIQKPGVVQRFVKFL 136
Query: 450 TNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWALGN 629
++N TLQFEAAWALTNIASG+ T++V++ GAV + + LL+ E+V EQAVWALGN
Sbjct: 137 ERNENCTLQFEAAWALTNIASGTFLHTKVVIETGAVPIFIKLLNSEHEDVQEQAVWALGN 196
Query: 630 IAGDSPYCRDIVLAAGVSPTL 692
IAGD+ CRD VL + P L
Sbjct: 197 IAGDNAECRDFVLNCEILPPL 217
Score = 58.8 bits (136), Expect = 2e-08
Identities = 34/106 (32%), Positives = 56/106 (52%)
Frame = +3
Query: 375 LSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGA 554
LS PN I AVI SG+ + +E L H + + A A+ NI +G QT+++++ A
Sbjct: 282 LSDGPNDKIQAVIDSGVCRRLVELLM-HNDYKVVSPALRAVGNIVTGDDIQTQVILNCSA 340
Query: 555 VNVLVGLLSGSTENVCEQAVWALGNIAGDSPYCRDIVLAAGVSPTL 692
+ L+ LLS E++ ++A W + NI + V+ A + P L
Sbjct: 341 LPCLLHLLSSPKESIRKEACWTVSNITAGNRAQIQAVIDANIFPVL 386
Score = 46.4 bits (105), Expect = 1e-04
Identities = 30/82 (36%), Positives = 46/82 (56%), Gaps = 2/82 (2%)
Frame = +3
Query: 408 VIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGS 587
VI++G VP FI+ L N ++ +Q +A WAL NIA ++ V++ + L+ LL+ S
Sbjct: 166 VIETGAVPIFIKLL-NSEHEDVQEQAVWALGNIAGDNAECRDFVLNCEILPPLLELLTNS 224
Query: 588 TE-NVCEQAVWALGNIA-GDSP 647
AVWAL N+ G +P
Sbjct: 225 NRLTTTRNAVWALSNLCRGKNP 246
Score = 45.2 bits (102), Expect = 2e-04
Identities = 27/82 (32%), Positives = 37/82 (45%)
Frame = +3
Query: 402 DAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLS 581
D V+ I+P +E LTN T A WAL+N+ G + +NVL LL
Sbjct: 206 DFVLNCEILPPLLELLTNSNRLTTTRNAVWALSNLCRGKNPPPNFSKVSPCLNVLSRLLF 265
Query: 582 GSTENVCEQAVWALGNIAGDSP 647
S +V WAL ++ D P
Sbjct: 266 SSDPDVLADVCWALSYLS-DGP 286
Score = 42.7 bits (96), Expect = 0.001
Identities = 21/81 (25%), Positives = 44/81 (54%), Gaps = 1/81 (1%)
Frame = +3
Query: 408 VIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGS 587
++ +P + L++ K +++ EA W ++NI +G+ Q + V+D VL+ +L +
Sbjct: 335 ILNCSALPCLLHLLSSPKE-SIRKEACWTVSNITAGNRAQIQAVIDANIFPVLIEILQKA 393
Query: 588 TENVCEQAVWALGN-IAGDSP 647
++A WA+ N +G +P
Sbjct: 394 EFRTRKEAAWAITNATSGGTP 414
Score = 38.7 bits (86), Expect = 0.020
Identities = 21/77 (27%), Positives = 36/77 (46%)
Frame = +3
Query: 462 NPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWALGNIAGD 641
+P + + WAL+ ++ G + + + V+D G LV LL + V A+ A+GNI
Sbjct: 268 DPDVLADVCWALSYLSDGPNDKIQAVIDSGVCRRLVELLMHNDYKVVSPALRAVGNIVTG 327
Query: 642 SPYCRDIVLAAGVSPTL 692
++L P L
Sbjct: 328 DDIQTQVILNCSALPCL 344
>AL132795-5|CAI20500.1| 539|Homo sapiens karyopherin alpha 5
(importin alpha 6) protein.
Length = 539
Score = 220 bits (537), Expect = 5e-57
Identities = 113/201 (56%), Positives = 147/201 (73%), Gaps = 8/201 (3%)
Frame = +3
Query: 114 YKNVGLSADELRRRREEEGVQLRKQKREQQLFKRRNVNLPGTNAAGAASQ-EDINISPS- 287
YKN L+ E+RRRREEEG+QLRKQKRE+QLFKRRNV LP + + S +D +IS +
Sbjct: 17 YKNKALNPQEMRRRREEEGIQLRKQKREEQLFKRRNVYLPRNDESMLESPIQDPDISSTV 76
Query: 288 -----DCITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQS-GIVPKFIEFL 449
+ +T DMV ++ +N ++Q+ ATQKFRKLLSKEPNPPID VIQ G+V +F++FL
Sbjct: 77 PIPEEEVVTTDMVQMIFSNNADQQLTATQKFRKLLSKEPNPPIDQVIQKPGVVQRFVKFL 136
Query: 450 TNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWALGN 629
++N TLQFEAAWALTNIASG+ T++V++ GAV + + LL+ E+V EQAVWALGN
Sbjct: 137 ERNENCTLQFEAAWALTNIASGTFLHTKVVIETGAVPIFIKLLNSEHEDVQEQAVWALGN 196
Query: 630 IAGDSPYCRDIVLAAGVSPTL 692
IAGD+ CRD VL + P L
Sbjct: 197 IAGDNAECRDFVLNCEILPPL 217
Score = 58.8 bits (136), Expect = 2e-08
Identities = 34/106 (32%), Positives = 56/106 (52%)
Frame = +3
Query: 375 LSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGA 554
LS PN I AVI SG+ + +E L H + + A A+ NI +G QT+++++ A
Sbjct: 282 LSDGPNDKIQAVIDSGVCRRLVELLM-HNDYKVVSPALRAVGNIVTGDDIQTQVILNCSA 340
Query: 555 VNVLVGLLSGSTENVCEQAVWALGNIAGDSPYCRDIVLAAGVSPTL 692
+ L+ LLS E++ ++A W + NI + V+ A + P L
Sbjct: 341 LPCLLHLLSSPKESIRKEACWTVSNITAGNRAQIQAVIDANIFPVL 386
Score = 46.4 bits (105), Expect = 1e-04
Identities = 30/82 (36%), Positives = 46/82 (56%), Gaps = 2/82 (2%)
Frame = +3
Query: 408 VIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGS 587
VI++G VP FI+ L N ++ +Q +A WAL NIA ++ V++ + L+ LL+ S
Sbjct: 166 VIETGAVPIFIKLL-NSEHEDVQEQAVWALGNIAGDNAECRDFVLNCEILPPLLELLTNS 224
Query: 588 TE-NVCEQAVWALGNIA-GDSP 647
AVWAL N+ G +P
Sbjct: 225 NRLTTTRNAVWALSNLCRGKNP 246
Score = 45.2 bits (102), Expect = 2e-04
Identities = 27/82 (32%), Positives = 37/82 (45%)
Frame = +3
Query: 402 DAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLS 581
D V+ I+P +E LTN T A WAL+N+ G + +NVL LL
Sbjct: 206 DFVLNCEILPPLLELLTNSNRLTTTRNAVWALSNLCRGKNPPPNFSKVSPCLNVLSRLLF 265
Query: 582 GSTENVCEQAVWALGNIAGDSP 647
S +V WAL ++ D P
Sbjct: 266 SSDPDVLADVCWALSYLS-DGP 286
Score = 42.7 bits (96), Expect = 0.001
Identities = 21/81 (25%), Positives = 44/81 (54%), Gaps = 1/81 (1%)
Frame = +3
Query: 408 VIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGS 587
++ +P + L++ K +++ EA W ++NI +G+ Q + V+D VL+ +L +
Sbjct: 335 ILNCSALPCLLHLLSSPKE-SIRKEACWTVSNITAGNRAQIQAVIDANIFPVLIEILQKA 393
Query: 588 TENVCEQAVWALGN-IAGDSP 647
++A WA+ N +G +P
Sbjct: 394 EFRTRKEAAWAITNATSGGTP 414
Score = 38.7 bits (86), Expect = 0.020
Identities = 21/77 (27%), Positives = 36/77 (46%)
Frame = +3
Query: 462 NPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWALGNIAGD 641
+P + + WAL+ ++ G + + + V+D G LV LL + V A+ A+GNI
Sbjct: 268 DPDVLADVCWALSYLSDGPNDKIQAVIDSGVCRRLVELLMHNDYKVVSPALRAVGNIVTG 327
Query: 642 SPYCRDIVLAAGVSPTL 692
++L P L
Sbjct: 328 DDIQTQVILNCSALPCL 344
>AF005361-1|AAC51868.1| 536|Homo sapiens importin alpha 6 protein.
Length = 536
Score = 219 bits (536), Expect = 6e-57
Identities = 114/201 (56%), Positives = 147/201 (73%), Gaps = 8/201 (3%)
Frame = +3
Query: 114 YKNVGLSADELRRRREEEGVQLRKQKREQQLFKRRNVNLPGTNAAGAASQ-EDINIS--- 281
YKN L+ E+RRRREEEG+QLRKQKRE+QLFKRRNV LP + + S +D +IS
Sbjct: 14 YKNKALNPQEMRRRREEEGIQLRKQKREEQLFKRRNVYLPRNDESMLESPIQDSDISSTV 73
Query: 282 --PSD-CITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQS-GIVPKFIEFL 449
P + +T DMV ++ +N ++Q+ ATQKFRKLLSKEPNPPID VIQ G+V +F++FL
Sbjct: 74 PIPEEGVVTTDMVQMIFSNNADQQLTATQKFRKLLSKEPNPPIDQVIQKPGVVQRFVKFL 133
Query: 450 TNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWALGN 629
++N TLQFEAAWALTNIASG+ T++V++ GAV + + LL+ E+V EQAVWALGN
Sbjct: 134 ERNENCTLQFEAAWALTNIASGTFLHTKVVIETGAVPIFIKLLNSEHEDVQEQAVWALGN 193
Query: 630 IAGDSPYCRDIVLAAGVSPTL 692
IAGD+ CRD VL + P L
Sbjct: 194 IAGDNAECRDFVLNCEILPPL 214
Score = 58.8 bits (136), Expect = 2e-08
Identities = 34/106 (32%), Positives = 56/106 (52%)
Frame = +3
Query: 375 LSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGA 554
LS PN I AVI SG+ + +E L H + + A A+ NI +G QT+++++ A
Sbjct: 279 LSDGPNDKIQAVIDSGVCRRLVELLM-HNDYKVVSPALRAVGNIVTGDDIQTQVILNCSA 337
Query: 555 VNVLVGLLSGSTENVCEQAVWALGNIAGDSPYCRDIVLAAGVSPTL 692
+ L+ LLS E++ ++A W + NI + V+ A + P L
Sbjct: 338 LPCLLHLLSSPKESIRKEACWTVSNITAGNRAQIQAVIDANIFPVL 383
Score = 46.4 bits (105), Expect = 1e-04
Identities = 30/82 (36%), Positives = 46/82 (56%), Gaps = 2/82 (2%)
Frame = +3
Query: 408 VIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGS 587
VI++G VP FI+ L N ++ +Q +A WAL NIA ++ V++ + L+ LL+ S
Sbjct: 163 VIETGAVPIFIKLL-NSEHEDVQEQAVWALGNIAGDNAECRDFVLNCEILPPLLELLTNS 221
Query: 588 TE-NVCEQAVWALGNIA-GDSP 647
AVWAL N+ G +P
Sbjct: 222 NRLTTTRNAVWALSNLCRGKNP 243
Score = 45.2 bits (102), Expect = 2e-04
Identities = 27/82 (32%), Positives = 37/82 (45%)
Frame = +3
Query: 402 DAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLS 581
D V+ I+P +E LTN T A WAL+N+ G + +NVL LL
Sbjct: 203 DFVLNCEILPPLLELLTNSNRLTTTRNAVWALSNLCRGKNPPPNFSKVSPCLNVLSRLLF 262
Query: 582 GSTENVCEQAVWALGNIAGDSP 647
S +V WAL ++ D P
Sbjct: 263 SSDPDVLADVCWALSYLS-DGP 283
Score = 42.7 bits (96), Expect = 0.001
Identities = 21/81 (25%), Positives = 44/81 (54%), Gaps = 1/81 (1%)
Frame = +3
Query: 408 VIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGS 587
++ +P + L++ K +++ EA W ++NI +G+ Q + V+D VL+ +L +
Sbjct: 332 ILNCSALPCLLHLLSSPKE-SIRKEACWTVSNITAGNRAQIQAVIDANIFPVLIEILQKA 390
Query: 588 TENVCEQAVWALGN-IAGDSP 647
++A WA+ N +G +P
Sbjct: 391 EFRTRKEAAWAITNATSGGTP 411
Score = 38.7 bits (86), Expect = 0.020
Identities = 21/77 (27%), Positives = 36/77 (46%)
Frame = +3
Query: 462 NPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWALGNIAGD 641
+P + + WAL+ ++ G + + + V+D G LV LL + V A+ A+GNI
Sbjct: 265 DPDVLADVCWALSYLSDGPNDKIQAVIDSGVCRRLVELLMHNDYKVVSPALRAVGNIVTG 324
Query: 642 SPYCRDIVLAAGVSPTL 692
++L P L
Sbjct: 325 DDIQTQVILNCSALPCL 341
>BC090864-1|AAH90864.1| 538|Homo sapiens karyopherin alpha 1
(importin alpha 5) protein.
Length = 538
Score = 218 bits (532), Expect = 2e-56
Identities = 116/203 (57%), Positives = 141/203 (69%), Gaps = 10/203 (4%)
Frame = +3
Query: 114 YKNVGLSADELRRRREEEGVQLRKQKREQQLFKRRNVNLPGTNAA------GAASQEDIN 275
YKN L+ DE+RRRREEEG+QLRKQKRE+QLFKRRNV G + IN
Sbjct: 14 YKNKSLNPDEMRRRREEEGLQLRKQKREEQLFKRRNVATAEEETEEEVMSDGGFHEAQIN 73
Query: 276 ---ISPSDCITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQS-GIVPKFIE 443
++P IT DM+ ++ +PE+Q+ ATQKFRKLLSKEPNPPID VI + G+V +F+E
Sbjct: 74 NMEMAPGGVITSDMIEMIFSKSPEQQLSATQKFRKLLSKEPNPPIDEVISTPGVVARFVE 133
Query: 444 FLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWAL 623
FL +N TLQFE+AW LTNIASG+S QTRIV+ GAV + + LLS E+V EQAVWAL
Sbjct: 134 FLKRKENCTLQFESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFEDVQEQAVWAL 193
Query: 624 GNIAGDSPYCRDIVLAAGVSPTL 692
GNIAGDS RD VL + P L
Sbjct: 194 GNIAGDSTMYRDYVLDCNILPPL 216
Score = 58.8 bits (136), Expect = 2e-08
Identities = 49/169 (28%), Positives = 81/169 (47%), Gaps = 5/169 (2%)
Frame = +3
Query: 201 QLFKRRNVNLPGTNAAGAASQEDINISPSD---CITPDM-VLAVYLDNPEEQVIATQKFR 368
QLF ++N NA A S SP ++P + VL+ L + V+A +
Sbjct: 218 QLFSKQNRLTMTRNAVWALSNLCRGKSPPPEFAKVSPCLNVLSWLLFVSDTDVLADACWA 277
Query: 369 -KLLSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVD 545
LS PN I AVI +G+ + +E L H + + A A+ NI +G QT+++++
Sbjct: 278 LSYLSDGPNDKIQAVIDAGVCRRLVELLM-HNDYKVVSPALRAVGNIVTGDDIQTQVILN 336
Query: 546 YGAVNVLVGLLSGSTENVCEQAVWALGNIAGDSPYCRDIVLAAGVSPTL 692
A+ L+ LLS E++ ++A W + NI + V+ A + P L
Sbjct: 337 CSALQSLLHLLSSPKESIKKEACWTISNITAGNRAQIQTVIDANIFPAL 385
Score = 49.2 bits (112), Expect = 1e-05
Identities = 33/82 (40%), Positives = 44/82 (53%), Gaps = 2/82 (2%)
Frame = +3
Query: 408 VIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGS 587
VIQ+G VP FIE L++ +Q +A WAL NIA S+ V+D + L+ L S
Sbjct: 165 VIQAGAVPIFIELLSSEFED-VQEQAVWALGNIAGDSTMYRDYVLDCNILPPLLQLFSKQ 223
Query: 588 TE-NVCEQAVWALGNIA-GDSP 647
+ AVWAL N+ G SP
Sbjct: 224 NRLTMTRNAVWALSNLCRGKSP 245
Score = 44.4 bits (100), Expect = 4e-04
Identities = 29/94 (30%), Positives = 43/94 (45%), Gaps = 1/94 (1%)
Frame = +3
Query: 402 DAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLS 581
D V+ I+P ++ + T+ A WAL+N+ G S +NVL LL
Sbjct: 205 DYVLDCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKSPPPEFAKVSPCLNVLSWLLF 264
Query: 582 GSTENVCEQAVWALGNIAGDSPYCR-DIVLAAGV 680
S +V A WAL ++ D P + V+ AGV
Sbjct: 265 VSDTDVLADACWALSYLS-DGPNDKIQAVIDAGV 297
Score = 43.6 bits (98), Expect = 7e-04
Identities = 28/79 (35%), Positives = 40/79 (50%), Gaps = 1/79 (1%)
Frame = +3
Query: 399 IDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSG-QTRIVVDYGAVNVLVGL 575
I VI + I P I L + T + EAAWA+TN SG S Q + +V+ G + L L
Sbjct: 373 IQTVIDANIFPALISILQTAEFRTRK-EAAWAITNATSGGSAEQIKYLVELGCIKPLCDL 431
Query: 576 LSGSTENVCEQAVWALGNI 632
L+ + + A+ L NI
Sbjct: 432 LTVMDSKIVQVALNGLENI 450
Score = 39.5 bits (88), Expect = 0.011
Identities = 17/74 (22%), Positives = 38/74 (51%)
Frame = +3
Query: 408 VIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGS 587
++ + + L++ K +++ EA W ++NI +G+ Q + V+D L+ +L +
Sbjct: 334 ILNCSALQSLLHLLSSPKE-SIKKEACWTISNITAGNRAQIQTVIDANIFPALISILQTA 392
Query: 588 TENVCEQAVWALGN 629
++A WA+ N
Sbjct: 393 EFRTRKEAAWAITN 406
>S75295-1|AAC60648.1| 538|Homo sapiens nucleoprotein interactor 1
protein.
Length = 538
Score = 217 bits (530), Expect = 3e-56
Identities = 113/203 (55%), Positives = 141/203 (69%), Gaps = 10/203 (4%)
Frame = +3
Query: 114 YKNVGLSADELRRRREEEGVQLRKQKREQQLFKRRNV---------NLPGTNAAGAASQE 266
YKN L+ DE+RRRREEEG+QLRKQKRE+QLFKRRNV + A
Sbjct: 14 YKNKSLNPDEMRRRREEEGLQLRKQKREEQLFKRRNVATAEEETEEEVMSDGGFHEAQIS 73
Query: 267 DINISPSDCITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQS-GIVPKFIE 443
++ ++P IT DM+ ++ +PE+Q+ ATQKFRKLLSKEPNPPID VI + G+V +F+E
Sbjct: 74 NMEMAPGGVITSDMIEMIFSKSPEQQLSATQKFRKLLSKEPNPPIDEVISTPGVVARFVE 133
Query: 444 FLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWAL 623
FL +N +LQFE+AW LTNIASG+S QTRIV+ AV + + LLS E+V EQAVWAL
Sbjct: 134 FLKRKENCSLQFESAWVLTNIASGNSLQTRIVIQARAVPIFIELLSSEFEDVQEQAVWAL 193
Query: 624 GNIAGDSPYCRDIVLAAGVSPTL 692
GNIAGDS CRD VL + P L
Sbjct: 194 GNIAGDSTMCRDYVLDCNILPPL 216
Score = 58.8 bits (136), Expect = 2e-08
Identities = 49/169 (28%), Positives = 81/169 (47%), Gaps = 5/169 (2%)
Frame = +3
Query: 201 QLFKRRNVNLPGTNAAGAASQEDINISPSD---CITPDM-VLAVYLDNPEEQVIATQKFR 368
QLF ++N NA A S SP ++P + VL+ L + V+A +
Sbjct: 218 QLFSKQNRLTMTRNAVWALSNLCRGKSPPPEFAKVSPCLNVLSWLLFVSDTDVLADACWA 277
Query: 369 -KLLSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVD 545
LS PN I AVI +G+ + +E L H + + A A+ NI +G QT+++++
Sbjct: 278 LSYLSDGPNDKIQAVIDAGVCRRLVELLM-HNDYKVVSPALRAVGNIVTGDDIQTQVILN 336
Query: 546 YGAVNVLVGLLSGSTENVCEQAVWALGNIAGDSPYCRDIVLAAGVSPTL 692
A+ L+ LLS E++ ++A W + NI + V+ A + P L
Sbjct: 337 CSALQSLLHLLSSPKESIKKEACWTISNITAGNRAQIQTVIDANIFPAL 385
Score = 45.2 bits (102), Expect = 2e-04
Identities = 32/82 (39%), Positives = 43/82 (52%), Gaps = 2/82 (2%)
Frame = +3
Query: 408 VIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGS 587
VIQ+ VP FIE L++ +Q +A WAL NIA S+ V+D + L+ L S
Sbjct: 165 VIQARAVPIFIELLSSEFED-VQEQAVWALGNIAGDSTMCRDYVLDCNILPPLLQLFSKQ 223
Query: 588 TE-NVCEQAVWALGNIA-GDSP 647
+ AVWAL N+ G SP
Sbjct: 224 NRLTMTRNAVWALSNLCRGKSP 245
Score = 44.4 bits (100), Expect = 4e-04
Identities = 29/94 (30%), Positives = 43/94 (45%), Gaps = 1/94 (1%)
Frame = +3
Query: 402 DAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLS 581
D V+ I+P ++ + T+ A WAL+N+ G S +NVL LL
Sbjct: 205 DYVLDCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKSPPPEFAKVSPCLNVLSWLLF 264
Query: 582 GSTENVCEQAVWALGNIAGDSPYCR-DIVLAAGV 680
S +V A WAL ++ D P + V+ AGV
Sbjct: 265 VSDTDVLADACWALSYLS-DGPNDKIQAVIDAGV 297
Score = 43.6 bits (98), Expect = 7e-04
Identities = 28/79 (35%), Positives = 40/79 (50%), Gaps = 1/79 (1%)
Frame = +3
Query: 399 IDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSG-QTRIVVDYGAVNVLVGL 575
I VI + I P I L + T + EAAWA+TN SG S Q + +V+ G + L L
Sbjct: 373 IQTVIDANIFPALISILQTAEFRTRK-EAAWAITNATSGGSAEQIKYLVELGCIKPLCDL 431
Query: 576 LSGSTENVCEQAVWALGNI 632
L+ + + A+ L NI
Sbjct: 432 LTVMDSKIVQVALNGLENI 450
Score = 39.5 bits (88), Expect = 0.011
Identities = 17/74 (22%), Positives = 38/74 (51%)
Frame = +3
Query: 408 VIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGS 587
++ + + L++ K +++ EA W ++NI +G+ Q + V+D L+ +L +
Sbjct: 334 ILNCSALQSLLHLLSSPKE-SIKKEACWTISNITAGNRAQIQTVIDANIFPALISILQTA 392
Query: 588 TENVCEQAVWALGN 629
++A WA+ N
Sbjct: 393 EFRTRKEAAWAITN 406
>BT009843-1|AAP88845.1| 536|Homo sapiens karyopherin alpha 6
(importin alpha 7) protein.
Length = 536
Score = 212 bits (517), Expect = 1e-54
Identities = 113/194 (58%), Positives = 141/194 (72%), Gaps = 5/194 (2%)
Frame = +3
Query: 114 YKNVGLSADELRRRREEEGVQLRKQKREQQLFKRRNVNLPGTNAAGAASQ-EDINISPS- 287
YKN L+ +E+RRRREEEG+QLRKQKREQQLFKRRNV L AA S D +S +
Sbjct: 17 YKNNALNPEEMRRRREEEGIQLRKQKREQQLFKRRNVELINEEAAMFDSLLMDSYVSSTT 76
Query: 288 --DCITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQSG-IVPKFIEFLTNH 458
IT +MV ++ D+ + Q+ TQKFRKLLSKEP+PPID VI + +V +F+EFL +
Sbjct: 77 GESVITREMVEMLFSDDSDLQLATTQKFRKLLSKEPSPPIDEVINTPRVVDRFVEFLKRN 136
Query: 459 KNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWALGNIAG 638
+N TLQFEAAWALTNIASG+S QT+IV++ GAV + + LL+ E+V EQAVWALGNIAG
Sbjct: 137 ENCTLQFEAAWALTNIASGTSQQTKIVIEAGAVPIFIELLNSDFEDVQEQAVWALGNIAG 196
Query: 639 DSPYCRDIVLAAGV 680
DS CRD VL +
Sbjct: 197 DSSVCRDYVLNCSI 210
Score = 59.7 bits (138), Expect = 1e-08
Identities = 34/106 (32%), Positives = 56/106 (52%)
Frame = +3
Query: 375 LSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGA 554
LS PN I AVI SG+ + +E L H + + A A+ NI +G QT+++++ A
Sbjct: 279 LSDGPNEKIQAVIDSGVCRRLVELLM-HNDYKVASPALRAVGNIVTGDDIQTQVILNCSA 337
Query: 555 VNVLVGLLSGSTENVCEQAVWALGNIAGDSPYCRDIVLAAGVSPTL 692
+ L+ LLS E++ ++A W + NI + V+ A + P L
Sbjct: 338 LPCLLHLLSSPKESIRKEACWTISNITAGNRAQIQAVIDANIFPVL 383
Score = 52.8 bits (121), Expect = 1e-06
Identities = 35/82 (42%), Positives = 47/82 (57%), Gaps = 2/82 (2%)
Frame = +3
Query: 408 VIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGS 587
VI++G VP FIE L N +Q +A WAL NIA SS V++ +N L+ LL+ S
Sbjct: 163 VIEAGAVPIFIELL-NSDFEDVQEQAVWALGNIAGDSSVCRDYVLNCSILNPLLTLLTKS 221
Query: 588 TE-NVCEQAVWALGNIA-GDSP 647
T + AVWAL N+ G +P
Sbjct: 222 TRLTMTRNAVWALSNLCRGKNP 243
Score = 43.2 bits (97), Expect = 0.001
Identities = 29/106 (27%), Positives = 47/106 (44%)
Frame = +3
Query: 375 LSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGA 554
L + NPP + S +P L + + L +A WAL+ ++ G + + + V+D G
Sbjct: 237 LCRGKNPPPEFAKVSPCLPVLSRLLFSSDSDLLA-DACWALSYLSDGPNEKIQAVIDSGV 295
Query: 555 VNVLVGLLSGSTENVCEQAVWALGNIAGDSPYCRDIVLAAGVSPTL 692
LV LL + V A+ A+GNI ++L P L
Sbjct: 296 CRRLVELLMHNDYKVASPALRAVGNIVTGDDIQTQVILNCSALPCL 341
Score = 43.2 bits (97), Expect = 0.001
Identities = 21/81 (25%), Positives = 44/81 (54%), Gaps = 1/81 (1%)
Frame = +3
Query: 408 VIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGS 587
++ +P + L++ K +++ EA W ++NI +G+ Q + V+D VL+ +L +
Sbjct: 332 ILNCSALPCLLHLLSSPKE-SIRKEACWTISNITAGNRAQIQAVIDANIFPVLIEILQKA 390
Query: 588 TENVCEQAVWALGN-IAGDSP 647
++A WA+ N +G +P
Sbjct: 391 EFRTRKEAAWAITNATSGGTP 411
>BC020520-1|AAH20520.1| 536|Homo sapiens karyopherin alpha 6
(importin alpha 7) protein.
Length = 536
Score = 212 bits (517), Expect = 1e-54
Identities = 113/194 (58%), Positives = 141/194 (72%), Gaps = 5/194 (2%)
Frame = +3
Query: 114 YKNVGLSADELRRRREEEGVQLRKQKREQQLFKRRNVNLPGTNAAGAASQ-EDINISPS- 287
YKN L+ +E+RRRREEEG+QLRKQKREQQLFKRRNV L AA S D +S +
Sbjct: 17 YKNNALNPEEMRRRREEEGIQLRKQKREQQLFKRRNVELINEEAAMFDSLLMDSYVSSTT 76
Query: 288 --DCITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQSG-IVPKFIEFLTNH 458
IT +MV ++ D+ + Q+ TQKFRKLLSKEP+PPID VI + +V +F+EFL +
Sbjct: 77 GESVITREMVEMLFSDDSDLQLATTQKFRKLLSKEPSPPIDEVINTPRVVDRFVEFLKRN 136
Query: 459 KNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWALGNIAG 638
+N TLQFEAAWALTNIASG+S QT+IV++ GAV + + LL+ E+V EQAVWALGNIAG
Sbjct: 137 ENCTLQFEAAWALTNIASGTSQQTKIVIEAGAVPIFIELLNSDFEDVQEQAVWALGNIAG 196
Query: 639 DSPYCRDIVLAAGV 680
DS CRD VL +
Sbjct: 197 DSSVCRDYVLNCSI 210
Score = 59.7 bits (138), Expect = 1e-08
Identities = 34/106 (32%), Positives = 56/106 (52%)
Frame = +3
Query: 375 LSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGA 554
LS PN I AVI SG+ + +E L H + + A A+ NI +G QT+++++ A
Sbjct: 279 LSDGPNEKIQAVIDSGVCRRLVELLM-HNDYKVASPALRAVGNIVTGDDIQTQVILNCSA 337
Query: 555 VNVLVGLLSGSTENVCEQAVWALGNIAGDSPYCRDIVLAAGVSPTL 692
+ L+ LLS E++ ++A W + NI + V+ A + P L
Sbjct: 338 LPCLLHLLSSPKESIRKEACWTISNITAGNRAQIQAVIDANIFPVL 383
Score = 52.8 bits (121), Expect = 1e-06
Identities = 35/82 (42%), Positives = 47/82 (57%), Gaps = 2/82 (2%)
Frame = +3
Query: 408 VIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGS 587
VI++G VP FIE L N +Q +A WAL NIA SS V++ +N L+ LL+ S
Sbjct: 163 VIEAGAVPIFIELL-NSDFEDVQEQAVWALGNIAGDSSVCRDYVLNCSILNPLLTLLTKS 221
Query: 588 TE-NVCEQAVWALGNIA-GDSP 647
T + AVWAL N+ G +P
Sbjct: 222 TRLTMTRNAVWALSNLCRGKNP 243
Score = 43.2 bits (97), Expect = 0.001
Identities = 29/106 (27%), Positives = 47/106 (44%)
Frame = +3
Query: 375 LSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGA 554
L + NPP + S +P L + + L +A WAL+ ++ G + + + V+D G
Sbjct: 237 LCRGKNPPPEFAKVSPCLPVLSRLLFSSDSDLLA-DACWALSYLSDGPNEKIQAVIDSGV 295
Query: 555 VNVLVGLLSGSTENVCEQAVWALGNIAGDSPYCRDIVLAAGVSPTL 692
LV LL + V A+ A+GNI ++L P L
Sbjct: 296 CRRLVELLMHNDYKVASPALRAVGNIVTGDDIQTQVILNCSALPCL 341
Score = 43.2 bits (97), Expect = 0.001
Identities = 21/81 (25%), Positives = 44/81 (54%), Gaps = 1/81 (1%)
Frame = +3
Query: 408 VIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGS 587
++ +P + L++ K +++ EA W ++NI +G+ Q + V+D VL+ +L +
Sbjct: 332 ILNCSALPCLLHLLSSPKE-SIRKEACWTISNITAGNRAQIQAVIDANIFPVLIEILQKA 390
Query: 588 TENVCEQAVWALGN-IAGDSP 647
++A WA+ N +G +P
Sbjct: 391 EFRTRKEAAWAITNATSGGTP 411
>AL445248-5|CAH71948.1| 536|Homo sapiens karyopherin alpha 6
(importin alpha 7) protein.
Length = 536
Score = 212 bits (517), Expect = 1e-54
Identities = 113/194 (58%), Positives = 141/194 (72%), Gaps = 5/194 (2%)
Frame = +3
Query: 114 YKNVGLSADELRRRREEEGVQLRKQKREQQLFKRRNVNLPGTNAAGAASQ-EDINISPS- 287
YKN L+ +E+RRRREEEG+QLRKQKREQQLFKRRNV L AA S D +S +
Sbjct: 17 YKNNALNPEEMRRRREEEGIQLRKQKREQQLFKRRNVELINEEAAMFDSLLMDSYVSSTT 76
Query: 288 --DCITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQSG-IVPKFIEFLTNH 458
IT +MV ++ D+ + Q+ TQKFRKLLSKEP+PPID VI + +V +F+EFL +
Sbjct: 77 GESVITREMVEMLFSDDSDLQLATTQKFRKLLSKEPSPPIDEVINTPRVVDRFVEFLKRN 136
Query: 459 KNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWALGNIAG 638
+N TLQFEAAWALTNIASG+S QT+IV++ GAV + + LL+ E+V EQAVWALGNIAG
Sbjct: 137 ENCTLQFEAAWALTNIASGTSQQTKIVIEAGAVPIFIELLNSDFEDVQEQAVWALGNIAG 196
Query: 639 DSPYCRDIVLAAGV 680
DS CRD VL +
Sbjct: 197 DSSVCRDYVLNCSI 210
Score = 59.7 bits (138), Expect = 1e-08
Identities = 34/106 (32%), Positives = 56/106 (52%)
Frame = +3
Query: 375 LSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGA 554
LS PN I AVI SG+ + +E L H + + A A+ NI +G QT+++++ A
Sbjct: 279 LSDGPNEKIQAVIDSGVCRRLVELLM-HNDYKVASPALRAVGNIVTGDDIQTQVILNCSA 337
Query: 555 VNVLVGLLSGSTENVCEQAVWALGNIAGDSPYCRDIVLAAGVSPTL 692
+ L+ LLS E++ ++A W + NI + V+ A + P L
Sbjct: 338 LPCLLHLLSSPKESIRKEACWTISNITAGNRAQIQAVIDANIFPVL 383
Score = 52.8 bits (121), Expect = 1e-06
Identities = 35/82 (42%), Positives = 47/82 (57%), Gaps = 2/82 (2%)
Frame = +3
Query: 408 VIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGS 587
VI++G VP FIE L N +Q +A WAL NIA SS V++ +N L+ LL+ S
Sbjct: 163 VIEAGAVPIFIELL-NSDFEDVQEQAVWALGNIAGDSSVCRDYVLNCSILNPLLTLLTKS 221
Query: 588 TE-NVCEQAVWALGNIA-GDSP 647
T + AVWAL N+ G +P
Sbjct: 222 TRLTMTRNAVWALSNLCRGKNP 243
Score = 43.2 bits (97), Expect = 0.001
Identities = 29/106 (27%), Positives = 47/106 (44%)
Frame = +3
Query: 375 LSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGA 554
L + NPP + S +P L + + L +A WAL+ ++ G + + + V+D G
Sbjct: 237 LCRGKNPPPEFAKVSPCLPVLSRLLFSSDSDLLA-DACWALSYLSDGPNEKIQAVIDSGV 295
Query: 555 VNVLVGLLSGSTENVCEQAVWALGNIAGDSPYCRDIVLAAGVSPTL 692
LV LL + V A+ A+GNI ++L P L
Sbjct: 296 CRRLVELLMHNDYKVASPALRAVGNIVTGDDIQTQVILNCSALPCL 341
Score = 43.2 bits (97), Expect = 0.001
Identities = 21/81 (25%), Positives = 44/81 (54%), Gaps = 1/81 (1%)
Frame = +3
Query: 408 VIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGS 587
++ +P + L++ K +++ EA W ++NI +G+ Q + V+D VL+ +L +
Sbjct: 332 ILNCSALPCLLHLLSSPKE-SIRKEACWTISNITAGNRAQIQAVIDANIFPVLIEILQKA 390
Query: 588 TENVCEQAVWALGN-IAGDSP 647
++A WA+ N +G +P
Sbjct: 391 EFRTRKEAAWAITNATSGGTP 411
>AL049795-3|CAI22056.1| 536|Homo sapiens karyopherin alpha 6
(importin alpha 7) protein.
Length = 536
Score = 212 bits (517), Expect = 1e-54
Identities = 113/194 (58%), Positives = 141/194 (72%), Gaps = 5/194 (2%)
Frame = +3
Query: 114 YKNVGLSADELRRRREEEGVQLRKQKREQQLFKRRNVNLPGTNAAGAASQ-EDINISPS- 287
YKN L+ +E+RRRREEEG+QLRKQKREQQLFKRRNV L AA S D +S +
Sbjct: 17 YKNNALNPEEMRRRREEEGIQLRKQKREQQLFKRRNVELINEEAAMFDSLLMDSYVSSTT 76
Query: 288 --DCITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQSG-IVPKFIEFLTNH 458
IT +MV ++ D+ + Q+ TQKFRKLLSKEP+PPID VI + +V +F+EFL +
Sbjct: 77 GESVITREMVEMLFSDDSDLQLATTQKFRKLLSKEPSPPIDEVINTPRVVDRFVEFLKRN 136
Query: 459 KNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWALGNIAG 638
+N TLQFEAAWALTNIASG+S QT+IV++ GAV + + LL+ E+V EQAVWALGNIAG
Sbjct: 137 ENCTLQFEAAWALTNIASGTSQQTKIVIEAGAVPIFIELLNSDFEDVQEQAVWALGNIAG 196
Query: 639 DSPYCRDIVLAAGV 680
DS CRD VL +
Sbjct: 197 DSSVCRDYVLNCSI 210
Score = 59.7 bits (138), Expect = 1e-08
Identities = 34/106 (32%), Positives = 56/106 (52%)
Frame = +3
Query: 375 LSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGA 554
LS PN I AVI SG+ + +E L H + + A A+ NI +G QT+++++ A
Sbjct: 279 LSDGPNEKIQAVIDSGVCRRLVELLM-HNDYKVASPALRAVGNIVTGDDIQTQVILNCSA 337
Query: 555 VNVLVGLLSGSTENVCEQAVWALGNIAGDSPYCRDIVLAAGVSPTL 692
+ L+ LLS E++ ++A W + NI + V+ A + P L
Sbjct: 338 LPCLLHLLSSPKESIRKEACWTISNITAGNRAQIQAVIDANIFPVL 383
Score = 52.8 bits (121), Expect = 1e-06
Identities = 35/82 (42%), Positives = 47/82 (57%), Gaps = 2/82 (2%)
Frame = +3
Query: 408 VIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGS 587
VI++G VP FIE L N +Q +A WAL NIA SS V++ +N L+ LL+ S
Sbjct: 163 VIEAGAVPIFIELL-NSDFEDVQEQAVWALGNIAGDSSVCRDYVLNCSILNPLLTLLTKS 221
Query: 588 TE-NVCEQAVWALGNIA-GDSP 647
T + AVWAL N+ G +P
Sbjct: 222 TRLTMTRNAVWALSNLCRGKNP 243
Score = 43.2 bits (97), Expect = 0.001
Identities = 29/106 (27%), Positives = 47/106 (44%)
Frame = +3
Query: 375 LSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGA 554
L + NPP + S +P L + + L +A WAL+ ++ G + + + V+D G
Sbjct: 237 LCRGKNPPPEFAKVSPCLPVLSRLLFSSDSDLLA-DACWALSYLSDGPNEKIQAVIDSGV 295
Query: 555 VNVLVGLLSGSTENVCEQAVWALGNIAGDSPYCRDIVLAAGVSPTL 692
LV LL + V A+ A+GNI ++L P L
Sbjct: 296 CRRLVELLMHNDYKVASPALRAVGNIVTGDDIQTQVILNCSALPCL 341
Score = 43.2 bits (97), Expect = 0.001
Identities = 21/81 (25%), Positives = 44/81 (54%), Gaps = 1/81 (1%)
Frame = +3
Query: 408 VIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGS 587
++ +P + L++ K +++ EA W ++NI +G+ Q + V+D VL+ +L +
Sbjct: 332 ILNCSALPCLLHLLSSPKE-SIRKEACWTISNITAGNRAQIQAVIDANIFPVLIEILQKA 390
Query: 588 TENVCEQAVWALGN-IAGDSP 647
++A WA+ N +G +P
Sbjct: 391 EFRTRKEAAWAITNATSGGTP 411
>AF060543-1|AAC15233.1| 536|Homo sapiens importin alpha 7 subunit
protein.
Length = 536
Score = 212 bits (517), Expect = 1e-54
Identities = 113/194 (58%), Positives = 141/194 (72%), Gaps = 5/194 (2%)
Frame = +3
Query: 114 YKNVGLSADELRRRREEEGVQLRKQKREQQLFKRRNVNLPGTNAAGAASQ-EDINISPS- 287
YKN L+ +E+RRRREEEG+QLRKQKREQQLFKRRNV L AA S D +S +
Sbjct: 17 YKNNALNPEEMRRRREEEGIQLRKQKREQQLFKRRNVELINEEAAMFDSLLMDSYVSSTT 76
Query: 288 --DCITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQSG-IVPKFIEFLTNH 458
IT +MV ++ D+ + Q+ TQKFRKLLSKEP+PPID VI + +V +F+EFL +
Sbjct: 77 GESVITREMVEMLFSDDSDLQLATTQKFRKLLSKEPSPPIDEVINTPRVVDRFVEFLKRN 136
Query: 459 KNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWALGNIAG 638
+N TLQFEAAWALTNIASG+S QT+IV++ GAV + + LL+ E+V EQAVWALGNIAG
Sbjct: 137 ENCTLQFEAAWALTNIASGTSQQTKIVIEAGAVPIFIELLNSDFEDVQEQAVWALGNIAG 196
Query: 639 DSPYCRDIVLAAGV 680
DS CRD VL +
Sbjct: 197 DSSVCRDYVLNCSI 210
Score = 59.7 bits (138), Expect = 1e-08
Identities = 34/106 (32%), Positives = 56/106 (52%)
Frame = +3
Query: 375 LSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGA 554
LS PN I AVI SG+ + +E L H + + A A+ NI +G QT+++++ A
Sbjct: 279 LSDGPNEKIQAVIDSGVCRRLVELLM-HNDYKVASPALRAVGNIVTGDDIQTQVILNCSA 337
Query: 555 VNVLVGLLSGSTENVCEQAVWALGNIAGDSPYCRDIVLAAGVSPTL 692
+ L+ LLS E++ ++A W + NI + V+ A + P L
Sbjct: 338 LPCLLHLLSSPKESIRKEACWTISNITAGNRAQIQAVIDANIFPVL 383
Score = 52.8 bits (121), Expect = 1e-06
Identities = 35/82 (42%), Positives = 47/82 (57%), Gaps = 2/82 (2%)
Frame = +3
Query: 408 VIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGS 587
VI++G VP FIE L N +Q +A WAL NIA SS V++ +N L+ LL+ S
Sbjct: 163 VIEAGAVPIFIELL-NSDFEDVQEQAVWALGNIAGDSSVCRDYVLNCSILNPLLTLLTKS 221
Query: 588 TE-NVCEQAVWALGNIA-GDSP 647
T + AVWAL N+ G +P
Sbjct: 222 TRLTMTRNAVWALSNLCRGKNP 243
Score = 43.2 bits (97), Expect = 0.001
Identities = 29/106 (27%), Positives = 47/106 (44%)
Frame = +3
Query: 375 LSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGA 554
L + NPP + S +P L + + L +A WAL+ ++ G + + + V+D G
Sbjct: 237 LCRGKNPPPEFAKVSPCLPVLSRLLFSSDSDLLA-DACWALSYLSDGPNEKIQAVIDSGV 295
Query: 555 VNVLVGLLSGSTENVCEQAVWALGNIAGDSPYCRDIVLAAGVSPTL 692
LV LL + V A+ A+GNI ++L P L
Sbjct: 296 CRRLVELLMHNDYKVASPALRAVGNIVTGDDIQTQVILNCSALPCL 341
Score = 43.2 bits (97), Expect = 0.001
Identities = 21/81 (25%), Positives = 44/81 (54%), Gaps = 1/81 (1%)
Frame = +3
Query: 408 VIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGS 587
++ +P + L++ K +++ EA W ++NI +G+ Q + V+D VL+ +L +
Sbjct: 332 ILNCSALPCLLHLLSSPKE-SIRKEACWTISNITAGNRAQIQAVIDANIFPVLIEILQKA 390
Query: 588 TENVCEQAVWALGN-IAGDSP 647
++A WA+ N +G +P
Sbjct: 391 EFRTRKEAAWAITNATSGGTP 411
>BT006665-1|AAP35311.1| 529|Homo sapiens karyopherin alpha 2 (RAG
cohort 1, importin alpha 1) protein.
Length = 529
Score = 182 bits (442), Expect = 1e-45
Identities = 93/197 (47%), Positives = 126/197 (63%), Gaps = 1/197 (0%)
Frame = +3
Query: 108 HRYKNVGLSADELRRRREEEGVQLRKQKREQQLFKRRNVNLPGTNAAGAASQEDINISPS 287
HR+KN G + E+RRRR E V+LRK K++ Q+ KRRNV+ +A + N
Sbjct: 15 HRFKNKGKDSTEMRRRRIEVNVELRKAKKDDQMLKRRNVSSFPDDATSPLQENRNNQGTV 74
Query: 288 DCITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQSGIVPKFIEFLTNHKNP 467
+ D+V + N E Q+ ATQ RKLLS+E PPID +I++G++PKF+ FL
Sbjct: 75 NWSVDDIVKGINSSNVENQLQATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGRTDCS 134
Query: 468 TLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWALGNIAGDSP 647
+QFE+AWALTNIASG+S QT++VVD GA+ + LL+ ++ EQAVWALGNIAGD
Sbjct: 135 PIQFESAWALTNIASGTSEQTKVVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGS 194
Query: 648 YCRDIVLAAG-VSPTLA 695
RD+V+ G V P LA
Sbjct: 195 VFRDLVIKYGAVDPLLA 211
Score = 64.5 bits (150), Expect = 4e-10
Identities = 40/126 (31%), Positives = 70/126 (55%), Gaps = 2/126 (1%)
Frame = +3
Query: 294 ITPDMVLAVYLDNPEEQVIATQKFR-KLLSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPT 470
I P +V ++ D+PE V+A + L+ PN I V+++G+VP+ ++ L + P
Sbjct: 252 ILPTLVRLLHHDDPE--VLADTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGASELPI 309
Query: 471 LQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWALGNI-AGDSP 647
+ A A+ NI +G+ QT++V+D GA+ V LL+ N+ ++A W + NI AG
Sbjct: 310 VT-PALRAIGNIVTGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQD 368
Query: 648 YCRDIV 665
+ +V
Sbjct: 369 QIQQVV 374
Score = 56.0 bits (129), Expect = 1e-07
Identities = 34/100 (34%), Positives = 53/100 (53%)
Frame = +3
Query: 378 SKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAV 557
+K P PPIDAV Q I+P + L +H +P + + WA++ + G + + +VV G V
Sbjct: 239 NKNPAPPIDAVEQ--ILPTLVRLL-HHDDPEVLADTCWAISYLTDGPNERIGMVVKTGVV 295
Query: 558 NVLVGLLSGSTENVCEQAVWALGNIAGDSPYCRDIVLAAG 677
LV LL S + A+ A+GNI + +V+ AG
Sbjct: 296 PQLVKLLGASELPIVTPALRAIGNIVTGTDEQTQVVIDAG 335
Score = 43.6 bits (98), Expect = 7e-04
Identities = 30/100 (30%), Positives = 45/100 (45%), Gaps = 5/100 (5%)
Frame = +3
Query: 408 VIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLS-- 581
V+ G +P FI L + + + +A WAL NIA S +V+ YGAV+ L+ LL+
Sbjct: 158 VVDGGAIPAFISLLAS-PHAHISEQAVWALGNIAGDGSVFRDLVIKYGAVDPLLALLAVP 216
Query: 582 GSTENVC---EQAVWALGNIAGDSPYCRDIVLAAGVSPTL 692
+ C W L N+ + I + PTL
Sbjct: 217 DMSSLACGYLRNLTWTLSNLCRNKNPAPPIDAVEQILPTL 256
Score = 37.5 bits (83), Expect = 0.046
Identities = 25/79 (31%), Positives = 38/79 (48%), Gaps = 1/79 (1%)
Frame = +3
Query: 399 IDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSS-GQTRIVVDYGAVNVLVGL 575
I V+ G+VP + L+ T Q EA WA+TN SG + Q +V G + L+ L
Sbjct: 370 IQQVVNHGLVPFLVSVLSKADFKT-QKEAVWAVTNYTSGGTVEQIVYLVHCGIIEPLMNL 428
Query: 576 LSGSTENVCEQAVWALGNI 632
L+ + + A+ NI
Sbjct: 429 LTAKDTKIILVILDAISNI 447
>BC005978-1|AAH05978.1| 529|Homo sapiens karyopherin alpha 2 (RAG
cohort 1, importin alpha 1) protein.
Length = 529
Score = 182 bits (442), Expect = 1e-45
Identities = 93/197 (47%), Positives = 126/197 (63%), Gaps = 1/197 (0%)
Frame = +3
Query: 108 HRYKNVGLSADELRRRREEEGVQLRKQKREQQLFKRRNVNLPGTNAAGAASQEDINISPS 287
HR+KN G + E+RRRR E V+LRK K++ Q+ KRRNV+ +A + N
Sbjct: 15 HRFKNKGKDSTEMRRRRIEVNVELRKAKKDDQMLKRRNVSSFPDDATSPLQENRNNQGTV 74
Query: 288 DCITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQSGIVPKFIEFLTNHKNP 467
+ D+V + N E Q+ ATQ RKLLS+E PPID +I++G++PKF+ FL
Sbjct: 75 NWSVDDIVKGINSSNVENQLQATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGRTDCS 134
Query: 468 TLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWALGNIAGDSP 647
+QFE+AWALTNIASG+S QT++VVD GA+ + LL+ ++ EQAVWALGNIAGD
Sbjct: 135 PIQFESAWALTNIASGTSEQTKVVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGS 194
Query: 648 YCRDIVLAAG-VSPTLA 695
RD+V+ G V P LA
Sbjct: 195 VFRDLVIKYGAVDPLLA 211
Score = 64.5 bits (150), Expect = 4e-10
Identities = 40/126 (31%), Positives = 70/126 (55%), Gaps = 2/126 (1%)
Frame = +3
Query: 294 ITPDMVLAVYLDNPEEQVIATQKFR-KLLSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPT 470
I P +V ++ D+PE V+A + L+ PN I V+++G+VP+ ++ L + P
Sbjct: 252 ILPTLVRLLHHDDPE--VLADTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGASELPI 309
Query: 471 LQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWALGNI-AGDSP 647
+ A A+ NI +G+ QT++V+D GA+ V LL+ N+ ++A W + NI AG
Sbjct: 310 VT-PALRAIGNIVTGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQD 368
Query: 648 YCRDIV 665
+ +V
Sbjct: 369 QIQQVV 374
Score = 56.0 bits (129), Expect = 1e-07
Identities = 34/100 (34%), Positives = 53/100 (53%)
Frame = +3
Query: 378 SKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAV 557
+K P PPIDAV Q I+P + L +H +P + + WA++ + G + + +VV G V
Sbjct: 239 NKNPAPPIDAVEQ--ILPTLVRLL-HHDDPEVLADTCWAISYLTDGPNERIGMVVKTGVV 295
Query: 558 NVLVGLLSGSTENVCEQAVWALGNIAGDSPYCRDIVLAAG 677
LV LL S + A+ A+GNI + +V+ AG
Sbjct: 296 PQLVKLLGASELPIVTPALRAIGNIVTGTDEQTQVVIDAG 335
Score = 43.6 bits (98), Expect = 7e-04
Identities = 30/100 (30%), Positives = 45/100 (45%), Gaps = 5/100 (5%)
Frame = +3
Query: 408 VIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLS-- 581
V+ G +P FI L + + + +A WAL NIA S +V+ YGAV+ L+ LL+
Sbjct: 158 VVDGGAIPAFISLLAS-PHAHISEQAVWALGNIAGDGSVFRDLVIKYGAVDPLLALLAVP 216
Query: 582 GSTENVC---EQAVWALGNIAGDSPYCRDIVLAAGVSPTL 692
+ C W L N+ + I + PTL
Sbjct: 217 DMSSLACGYLRNLTWTLSNLCRNKNPAPPIDAVEQILPTL 256
Score = 37.5 bits (83), Expect = 0.046
Identities = 25/79 (31%), Positives = 38/79 (48%), Gaps = 1/79 (1%)
Frame = +3
Query: 399 IDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSS-GQTRIVVDYGAVNVLVGL 575
I V+ G+VP + L+ T Q EA WA+TN SG + Q +V G + L+ L
Sbjct: 370 IQQVVNHGLVPFLVSVLSKADFKT-QKEAVWAVTNYTSGGTVEQIVYLVHCGIIEPLMNL 428
Query: 576 LSGSTENVCEQAVWALGNI 632
L+ + + A+ NI
Sbjct: 429 LTAKDTKIILVILDAISNI 447
>U28386-1|AAA69957.1| 529|Homo sapiens hSRP1alpha protein.
Length = 529
Score = 180 bits (438), Expect = 4e-45
Identities = 93/197 (47%), Positives = 125/197 (63%), Gaps = 1/197 (0%)
Frame = +3
Query: 108 HRYKNVGLSADELRRRREEEGVQLRKQKREQQLFKRRNVNLPGTNAAGAASQEDINISPS 287
HR+KN G + E+RRRR E V+LRK K++ Q+ KRRNV+ +A + N
Sbjct: 15 HRFKNKGKDSTEMRRRRIEVNVELRKAKKDDQMLKRRNVSSFPDDATSPLQENRNNQGTV 74
Query: 288 DCITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQSGIVPKFIEFLTNHKNP 467
+ D+V + N E Q+ ATQ RKLLS+E PPID +I++G++PKF+ FL
Sbjct: 75 NWSVDDIVKGINSSNVENQLQATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGRTDCS 134
Query: 468 TLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWALGNIAGDSP 647
+QFE+AWALTNIASG+S QT+ VVD GA+ + LL+ ++ EQAVWALGNIAGD
Sbjct: 135 PIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGS 194
Query: 648 YCRDIVLAAG-VSPTLA 695
RD+V+ G V P LA
Sbjct: 195 VFRDLVIKYGAVDPLLA 211
Score = 64.5 bits (150), Expect = 4e-10
Identities = 40/126 (31%), Positives = 70/126 (55%), Gaps = 2/126 (1%)
Frame = +3
Query: 294 ITPDMVLAVYLDNPEEQVIATQKFR-KLLSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPT 470
I P +V ++ D+PE V+A + L+ PN I V+++G+VP+ ++ L + P
Sbjct: 252 ILPTLVRLLHHDDPE--VLADTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGASELPI 309
Query: 471 LQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWALGNI-AGDSP 647
+ A A+ NI +G+ QT++V+D GA+ V LL+ N+ ++A W + NI AG
Sbjct: 310 VT-PALRAIGNIVTGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQD 368
Query: 648 YCRDIV 665
+ +V
Sbjct: 369 QIQQVV 374
Score = 56.0 bits (129), Expect = 1e-07
Identities = 34/100 (34%), Positives = 53/100 (53%)
Frame = +3
Query: 378 SKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAV 557
+K P PPIDAV Q I+P + L +H +P + + WA++ + G + + +VV G V
Sbjct: 239 NKNPAPPIDAVEQ--ILPTLVRLL-HHDDPEVLADTCWAISYLTDGPNERIGMVVKTGVV 295
Query: 558 NVLVGLLSGSTENVCEQAVWALGNIAGDSPYCRDIVLAAG 677
LV LL S + A+ A+GNI + +V+ AG
Sbjct: 296 PQLVKLLGASELPIVTPALRAIGNIVTGTDEQTQVVIDAG 335
Score = 45.2 bits (102), Expect = 2e-04
Identities = 31/101 (30%), Positives = 46/101 (45%), Gaps = 5/101 (4%)
Frame = +3
Query: 405 AVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLS- 581
AV+ G +P FI L + + + +A WAL NIA S +V+ YGAV+ L+ LL+
Sbjct: 157 AVVDGGAIPAFISLLAS-PHAHISEQAVWALGNIAGDGSVFRDLVIKYGAVDPLLALLAV 215
Query: 582 -GSTENVC---EQAVWALGNIAGDSPYCRDIVLAAGVSPTL 692
+ C W L N+ + I + PTL
Sbjct: 216 PDMSSLACGYLRNLTWTLSNLCRNKNPAPPIDAVEQILPTL 256
Score = 37.5 bits (83), Expect = 0.046
Identities = 25/79 (31%), Positives = 38/79 (48%), Gaps = 1/79 (1%)
Frame = +3
Query: 399 IDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSS-GQTRIVVDYGAVNVLVGL 575
I V+ G+VP + L+ T Q EA WA+TN SG + Q +V G + L+ L
Sbjct: 370 IQQVVNHGLVPFLVSVLSKADFKT-QKEAVWAVTNYTSGGTVEQIVYLVHCGIIEPLMNL 428
Query: 576 LSGSTENVCEQAVWALGNI 632
L+ + + A+ NI
Sbjct: 429 LTAKDTKIILVILDAISNI 447
>U09559-1|AAA65700.1| 529|Homo sapiens Rch1 protein.
Length = 529
Score = 180 bits (438), Expect = 4e-45
Identities = 93/197 (47%), Positives = 125/197 (63%), Gaps = 1/197 (0%)
Frame = +3
Query: 108 HRYKNVGLSADELRRRREEEGVQLRKQKREQQLFKRRNVNLPGTNAAGAASQEDINISPS 287
HR+KN G + E+RRRR E V+LRK K++ Q+ KRRNV+ +A + N
Sbjct: 15 HRFKNKGKDSTEMRRRRIEVNVELRKAKKDDQMLKRRNVSSFPDDATSPLQENRNNQGTV 74
Query: 288 DCITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQSGIVPKFIEFLTNHKNP 467
+ D+V + N E Q+ ATQ RKLLS+E PPID +I++G++PKF+ FL
Sbjct: 75 NWSVDDIVKGINSSNVENQLQATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGRTDCS 134
Query: 468 TLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWALGNIAGDSP 647
+QFE+AWALTNIASG+S QT+ VVD GA+ + LL+ ++ EQAVWALGNIAGD
Sbjct: 135 PIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGS 194
Query: 648 YCRDIVLAAG-VSPTLA 695
RD+V+ G V P LA
Sbjct: 195 VFRDLVIKYGAVDPLLA 211
Score = 64.5 bits (150), Expect = 4e-10
Identities = 40/126 (31%), Positives = 70/126 (55%), Gaps = 2/126 (1%)
Frame = +3
Query: 294 ITPDMVLAVYLDNPEEQVIATQKFR-KLLSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPT 470
I P +V ++ D+PE V+A + L+ PN I V+++G+VP+ ++ L + P
Sbjct: 252 ILPTLVRLLHHDDPE--VLADTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGASELPI 309
Query: 471 LQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWALGNI-AGDSP 647
+ A A+ NI +G+ QT++V+D GA+ V LL+ N+ ++A W + NI AG
Sbjct: 310 VT-PALRAIGNIVTGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQD 368
Query: 648 YCRDIV 665
+ +V
Sbjct: 369 QIQQVV 374
Score = 56.0 bits (129), Expect = 1e-07
Identities = 34/100 (34%), Positives = 53/100 (53%)
Frame = +3
Query: 378 SKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAV 557
+K P PPIDAV Q I+P + L +H +P + + WA++ + G + + +VV G V
Sbjct: 239 NKNPAPPIDAVEQ--ILPTLVRLL-HHDDPEVLADTCWAISYLTDGPNERIGMVVKTGVV 295
Query: 558 NVLVGLLSGSTENVCEQAVWALGNIAGDSPYCRDIVLAAG 677
LV LL S + A+ A+GNI + +V+ AG
Sbjct: 296 PQLVKLLGASELPIVTPALRAIGNIVTGTDEQTQVVIDAG 335
Score = 45.2 bits (102), Expect = 2e-04
Identities = 31/101 (30%), Positives = 46/101 (45%), Gaps = 5/101 (4%)
Frame = +3
Query: 405 AVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLS- 581
AV+ G +P FI L + + + +A WAL NIA S +V+ YGAV+ L+ LL+
Sbjct: 157 AVVDGGAIPAFISLLAS-PHAHISEQAVWALGNIAGDGSVFRDLVIKYGAVDPLLALLAV 215
Query: 582 -GSTENVC---EQAVWALGNIAGDSPYCRDIVLAAGVSPTL 692
+ C W L N+ + I + PTL
Sbjct: 216 PDMSSLACGYLRNLTWTLSNLCRNKNPAPPIDAVEQILPTL 256
Score = 37.5 bits (83), Expect = 0.046
Identities = 25/79 (31%), Positives = 38/79 (48%), Gaps = 1/79 (1%)
Frame = +3
Query: 399 IDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSS-GQTRIVVDYGAVNVLVGL 575
I V+ G+VP + L+ T Q EA WA+TN SG + Q +V G + L+ L
Sbjct: 370 IQQVVNHGLVPFLVSVLSKADFKT-QKEAVWAVTNYTSGGTVEQIVYLVHCGIIEPLMNL 428
Query: 576 LSGSTENVCEQAVWALGNI 632
L+ + + A+ NI
Sbjct: 429 LTAKDTKIILVILDAISNI 447
>BC053343-1|AAH53343.1| 529|Homo sapiens karyopherin alpha 2 (RAG
cohort 1, importin alpha 1) protein.
Length = 529
Score = 180 bits (438), Expect = 4e-45
Identities = 93/197 (47%), Positives = 125/197 (63%), Gaps = 1/197 (0%)
Frame = +3
Query: 108 HRYKNVGLSADELRRRREEEGVQLRKQKREQQLFKRRNVNLPGTNAAGAASQEDINISPS 287
HR+KN G + E+RRRR E V+LRK K++ Q+ KRRNV+ +A + N
Sbjct: 15 HRFKNKGKDSTEMRRRRIEVNVELRKAKKDDQMLKRRNVSSFPDDATSPLQENRNNQGTV 74
Query: 288 DCITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQSGIVPKFIEFLTNHKNP 467
+ D+V + N E Q+ ATQ RKLLS+E PPID +I++G++PKF+ FL
Sbjct: 75 NWSVDDIVKGINSSNVENQLQATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGRTDCS 134
Query: 468 TLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWALGNIAGDSP 647
+QFE+AWALTNIASG+S QT+ VVD GA+ + LL+ ++ EQAVWALGNIAGD
Sbjct: 135 PIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGS 194
Query: 648 YCRDIVLAAG-VSPTLA 695
RD+V+ G V P LA
Sbjct: 195 VFRDLVIKYGAVDPLLA 211
Score = 64.5 bits (150), Expect = 4e-10
Identities = 40/126 (31%), Positives = 70/126 (55%), Gaps = 2/126 (1%)
Frame = +3
Query: 294 ITPDMVLAVYLDNPEEQVIATQKFR-KLLSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPT 470
I P +V ++ D+PE V+A + L+ PN I V+++G+VP+ ++ L + P
Sbjct: 252 ILPTLVRLLHHDDPE--VLADTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGASELPI 309
Query: 471 LQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWALGNI-AGDSP 647
+ A A+ NI +G+ QT++V+D GA+ V LL+ N+ ++A W + NI AG
Sbjct: 310 VT-PALRAIGNIVTGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQD 368
Query: 648 YCRDIV 665
+ +V
Sbjct: 369 QIQQVV 374
Score = 56.0 bits (129), Expect = 1e-07
Identities = 34/100 (34%), Positives = 53/100 (53%)
Frame = +3
Query: 378 SKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAV 557
+K P PPIDAV Q I+P + L +H +P + + WA++ + G + + +VV G V
Sbjct: 239 NKNPAPPIDAVEQ--ILPTLVRLL-HHDDPEVLADTCWAISYLTDGPNERIGMVVKTGVV 295
Query: 558 NVLVGLLSGSTENVCEQAVWALGNIAGDSPYCRDIVLAAG 677
LV LL S + A+ A+GNI + +V+ AG
Sbjct: 296 PQLVKLLGASELPIVTPALRAIGNIVTGTDEQTQVVIDAG 335
Score = 44.8 bits (101), Expect = 3e-04
Identities = 31/101 (30%), Positives = 44/101 (43%), Gaps = 5/101 (4%)
Frame = +3
Query: 405 AVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLL-- 578
AV+ G +P FI L + + + +A WAL NIA S +V+ YGAV+ L+ LL
Sbjct: 157 AVVDGGAIPAFISLLAS-PHAHISEQAVWALGNIAGDGSVFRDLVIKYGAVDPLLALLAV 215
Query: 579 ---SGSTENVCEQAVWALGNIAGDSPYCRDIVLAAGVSPTL 692
S W L N+ + I + PTL
Sbjct: 216 PEMSSLACGYLRNLTWTLSNLCRNKNPAPPIDAVEQILPTL 256
Score = 37.5 bits (83), Expect = 0.046
Identities = 25/79 (31%), Positives = 38/79 (48%), Gaps = 1/79 (1%)
Frame = +3
Query: 399 IDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSS-GQTRIVVDYGAVNVLVGL 575
I V+ G+VP + L+ T Q EA WA+TN SG + Q +V G + L+ L
Sbjct: 370 IQQVVNHGLVPFLVSVLSKADFKT-QKEAVWAVTNYTSGGTVEQIVYLVHCGIIEPLMNL 428
Query: 576 LSGSTENVCEQAVWALGNI 632
L+ + + A+ NI
Sbjct: 429 LTAKDTKIILVILDAISNI 447
>AJ303086-1|CAC83080.1| 529|Homo sapiens karyopherin alpha 2
protein.
Length = 529
Score = 180 bits (438), Expect = 4e-45
Identities = 93/197 (47%), Positives = 125/197 (63%), Gaps = 1/197 (0%)
Frame = +3
Query: 108 HRYKNVGLSADELRRRREEEGVQLRKQKREQQLFKRRNVNLPGTNAAGAASQEDINISPS 287
HR+KN G + E+RRRR E V+LRK K++ Q+ KRRNV+ +A + N
Sbjct: 15 HRFKNKGKDSTEMRRRRIEVNVELRKAKKDDQMLKRRNVSSFPDDATSPLQENRNNQGTV 74
Query: 288 DCITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQSGIVPKFIEFLTNHKNP 467
+ D+V + N E Q+ ATQ RKLLS+E PPID +I++G++PKF+ FL
Sbjct: 75 NWSVDDIVKGINSSNVENQLQATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGRTDCS 134
Query: 468 TLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWALGNIAGDSP 647
+QFE+AWALTNIASG+S QT+ VVD GA+ + LL+ ++ EQAVWALGNIAGD
Sbjct: 135 PIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGS 194
Query: 648 YCRDIVLAAG-VSPTLA 695
RD+V+ G V P LA
Sbjct: 195 VFRDLVIKYGAVDPLLA 211
Score = 64.5 bits (150), Expect = 4e-10
Identities = 40/126 (31%), Positives = 70/126 (55%), Gaps = 2/126 (1%)
Frame = +3
Query: 294 ITPDMVLAVYLDNPEEQVIATQKFR-KLLSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPT 470
I P +V ++ D+PE V+A + L+ PN I V+++G+VP+ ++ L + P
Sbjct: 252 ILPTLVRLLHHDDPE--VLADTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGASELPI 309
Query: 471 LQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWALGNI-AGDSP 647
+ A A+ NI +G+ QT++V+D GA+ V LL+ N+ ++A W + NI AG
Sbjct: 310 VT-PALRAIGNIVTGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQD 368
Query: 648 YCRDIV 665
+ +V
Sbjct: 369 QIQQVV 374
Score = 56.0 bits (129), Expect = 1e-07
Identities = 34/100 (34%), Positives = 53/100 (53%)
Frame = +3
Query: 378 SKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAV 557
+K P PPIDAV Q I+P + L +H +P + + WA++ + G + + +VV G V
Sbjct: 239 NKNPAPPIDAVEQ--ILPTLVRLL-HHDDPEVLADTCWAISYLTDGPNERIGMVVKTGVV 295
Query: 558 NVLVGLLSGSTENVCEQAVWALGNIAGDSPYCRDIVLAAG 677
LV LL S + A+ A+GNI + +V+ AG
Sbjct: 296 PQLVKLLGASELPIVTPALRAIGNIVTGTDEQTQVVIDAG 335
Score = 45.2 bits (102), Expect = 2e-04
Identities = 31/101 (30%), Positives = 46/101 (45%), Gaps = 5/101 (4%)
Frame = +3
Query: 405 AVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLS- 581
AV+ G +P FI L + + + +A WAL NIA S +V+ YGAV+ L+ LL+
Sbjct: 157 AVVDGGAIPAFISLLAS-PHAHISEQAVWALGNIAGDGSVFRDLVIKYGAVDPLLALLAV 215
Query: 582 -GSTENVC---EQAVWALGNIAGDSPYCRDIVLAAGVSPTL 692
+ C W L N+ + I + PTL
Sbjct: 216 PDMSSLACGYLRNLTWTLSNLCRNKNPAPPIDAVEQILPTL 256
Score = 37.5 bits (83), Expect = 0.046
Identities = 25/79 (31%), Positives = 38/79 (48%), Gaps = 1/79 (1%)
Frame = +3
Query: 399 IDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSS-GQTRIVVDYGAVNVLVGL 575
I V+ G+VP + L+ T Q EA WA+TN SG + Q +V G + L+ L
Sbjct: 370 IQQVVNHGLVPFLVSVLSKADFKT-QKEAVWAVTNYTSGGTVEQIVYLVHCGIIEPLMNL 428
Query: 576 LSGSTENVCEQAVWALGNI 632
L+ + + A+ NI
Sbjct: 429 LTAKDTKIILVILDAISNI 447
>BC067848-1|AAH67848.1| 529|Homo sapiens karyopherin alpha 2 (RAG
cohort 1, importin alpha 1) protein.
Length = 529
Score = 178 bits (434), Expect = 1e-44
Identities = 92/197 (46%), Positives = 124/197 (62%), Gaps = 1/197 (0%)
Frame = +3
Query: 108 HRYKNVGLSADELRRRREEEGVQLRKQKREQQLFKRRNVNLPGTNAAGAASQEDINISPS 287
HR+KN G + E+RRRR E V+LRK K++ Q+ KRRNV+ +A + N
Sbjct: 15 HRFKNKGKDSTEMRRRRIEVNVELRKAKKDDQMLKRRNVSSFPDDATSPLQENRNNQGTV 74
Query: 288 DCITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQSGIVPKFIEFLTNHKNP 467
+ D+V + N E Q+ ATQ RKLLS+E PPID +I++G++PKF+ FL
Sbjct: 75 NWSVDDIVKGINSSNVENQLQATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGRTDCS 134
Query: 468 TLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWALGNIAGDSP 647
+QFE+AWALTNIASG+S QT+ VVD GA+ + LL+ ++ EQ VWALGNIAGD
Sbjct: 135 PIQFESAWALTNIASGTSEQTKAVVDGGAIRAFISLLASPHAHISEQDVWALGNIAGDGS 194
Query: 648 YCRDIVLAAG-VSPTLA 695
RD+V+ G V P LA
Sbjct: 195 VFRDLVIKYGAVDPLLA 211
Score = 64.5 bits (150), Expect = 4e-10
Identities = 40/126 (31%), Positives = 70/126 (55%), Gaps = 2/126 (1%)
Frame = +3
Query: 294 ITPDMVLAVYLDNPEEQVIATQKFR-KLLSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPT 470
I P +V ++ D+PE V+A + L+ PN I V+++G+VP+ ++ L + P
Sbjct: 252 ILPTLVRLLHHDDPE--VLADTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGASELPI 309
Query: 471 LQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWALGNI-AGDSP 647
+ A A+ NI +G+ QT++V+D GA+ V LL+ N+ ++A W + NI AG
Sbjct: 310 VT-PALRAIGNIVTGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQD 368
Query: 648 YCRDIV 665
+ +V
Sbjct: 369 QIQQVV 374
Score = 56.0 bits (129), Expect = 1e-07
Identities = 34/100 (34%), Positives = 53/100 (53%)
Frame = +3
Query: 378 SKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAV 557
+K P PPIDAV Q I+P + L +H +P + + WA++ + G + + +VV G V
Sbjct: 239 NKNPAPPIDAVEQ--ILPTLVRLL-HHDDPEVLADTCWAISYLTDGPNERIGMVVKTGVV 295
Query: 558 NVLVGLLSGSTENVCEQAVWALGNIAGDSPYCRDIVLAAG 677
LV LL S + A+ A+GNI + +V+ AG
Sbjct: 296 PQLVKLLGASELPIVTPALRAIGNIVTGTDEQTQVVIDAG 335
Score = 39.1 bits (87), Expect = 0.015
Identities = 29/101 (28%), Positives = 44/101 (43%), Gaps = 5/101 (4%)
Frame = +3
Query: 405 AVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLS- 581
AV+ G + FI L + + + + WAL NIA S +V+ YGAV+ L+ LL+
Sbjct: 157 AVVDGGAIRAFISLLAS-PHAHISEQDVWALGNIAGDGSVFRDLVIKYGAVDPLLALLAV 215
Query: 582 -GSTENVC---EQAVWALGNIAGDSPYCRDIVLAAGVSPTL 692
+ C W L N+ + I + PTL
Sbjct: 216 PDMSSLACGYLRNLTWTLSNLCRNKNPAPPIDAVEQILPTL 256
Score = 37.5 bits (83), Expect = 0.046
Identities = 25/79 (31%), Positives = 38/79 (48%), Gaps = 1/79 (1%)
Frame = +3
Query: 399 IDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSS-GQTRIVVDYGAVNVLVGL 575
I V+ G+VP + L+ T Q EA WA+TN SG + Q +V G + L+ L
Sbjct: 370 IQQVVNHGLVPFLVSVLSKADFKT-QKEAVWAVTNYTSGGTVEQIVYLVHCGIIEPLMNL 428
Query: 576 LSGSTENVCEQAVWALGNI 632
L+ + + A+ NI
Sbjct: 429 LTAKDTKIILVILDAISNI 447
>D89618-1|BAA20378.1| 521|Homo sapiens karyopherin alhph 3 protein.
Length = 521
Score = 172 bits (419), Expect = 9e-43
Identities = 91/189 (48%), Positives = 118/189 (62%)
Frame = +3
Query: 114 YKNVGLSADELRRRREEEGVQLRKQKREQQLFKRRNVNLPGTNAAGAASQEDINISPSDC 293
+KN G + +RR R E V+LRK KR++ L K+RNV P + S D + +
Sbjct: 15 FKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNV--PQEESL-EDSDVDADFKAQNV 71
Query: 294 ITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTL 473
++ DNP Q+ A Q RKLLS + NPPID +I+SGI+P ++ L NP+L
Sbjct: 72 TLEAILQNATSDNPVVQLSAVQAARKLLSSDQNPPIDDLIKSGILPILVKCLERDDNPSL 131
Query: 474 QFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWALGNIAGDSPYC 653
QFEAAWALTNIASG+S QT+ VV AV + + LL +NVCEQAVWALGNI GD P C
Sbjct: 132 QFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGPQC 191
Query: 654 RDIVLAAGV 680
RD V++ GV
Sbjct: 192 RDYVISLGV 200
Score = 58.4 bits (135), Expect = 2e-08
Identities = 34/101 (33%), Positives = 55/101 (54%)
Frame = +3
Query: 390 NPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLV 569
N I VI SG+VP F+ L +H+ +Q A A+ NI +G+ QT++V++ ++
Sbjct: 274 NEQIQMVIDSGVVP-FLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFP 332
Query: 570 GLLSGSTENVCEQAVWALGNIAGDSPYCRDIVLAAGVSPTL 692
LLS E + ++AVW L NI + V+ AG+ P +
Sbjct: 333 NLLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMI 373
Score = 49.2 bits (112), Expect = 1e-05
Identities = 32/101 (31%), Positives = 51/101 (50%)
Frame = +3
Query: 378 SKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAV 557
+K+P PP++ V + I+P L H + + + WAL+ + G + Q ++V+D G V
Sbjct: 230 NKDPPPPMETVQE--ILPALC-VLIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVV 286
Query: 558 NVLVGLLSGSTENVCEQAVWALGNIAGDSPYCRDIVLAAGV 680
LV LLS V A+ A+GNI + +VL V
Sbjct: 287 PFLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDV 327
Score = 44.0 bits (99), Expect = 5e-04
Identities = 18/62 (29%), Positives = 34/62 (54%)
Frame = +3
Query: 447 LTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWALG 626
L +H + EA W L+NI +G+ Q + V+D G + +++ L+ ++A WA+
Sbjct: 334 LLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAIS 393
Query: 627 NI 632
N+
Sbjct: 394 NL 395
Score = 30.3 bits (65), Expect = 7.0
Identities = 21/97 (21%), Positives = 36/97 (37%)
Frame = +3
Query: 402 DAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLS 581
D VI G+V + F++ T W + N+ + + L L+
Sbjct: 193 DYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPALCVLIY 252
Query: 582 GSTENVCEQAVWALGNIAGDSPYCRDIVLAAGVSPTL 692
+ N+ VWAL + +V+ +GV P L
Sbjct: 253 HTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFL 289
>BC024202-1|AAH24202.1| 521|Homo sapiens karyopherin alpha 3
(importin alpha 4) protein.
Length = 521
Score = 172 bits (418), Expect = 1e-42
Identities = 91/189 (48%), Positives = 118/189 (62%)
Frame = +3
Query: 114 YKNVGLSADELRRRREEEGVQLRKQKREQQLFKRRNVNLPGTNAAGAASQEDINISPSDC 293
+KN G + +RR R E V+LRK KR++ L K+RNV P + S D + +
Sbjct: 15 FKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNV--PQEESL-EDSDVDADFKAQNV 71
Query: 294 ITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTL 473
++ DNP Q+ A Q RKLLS + NPPID +I+SGI+P ++ L NP+L
Sbjct: 72 TLEAILQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNPSL 131
Query: 474 QFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWALGNIAGDSPYC 653
QFEAAWALTNIASG+S QT+ VV AV + + LL +NVCEQAVWALGNI GD P C
Sbjct: 132 QFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGPQC 191
Query: 654 RDIVLAAGV 680
RD V++ GV
Sbjct: 192 RDYVISLGV 200
Score = 58.4 bits (135), Expect = 2e-08
Identities = 34/101 (33%), Positives = 55/101 (54%)
Frame = +3
Query: 390 NPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLV 569
N I VI SG+VP F+ L +H+ +Q A A+ NI +G+ QT++V++ ++
Sbjct: 274 NEQIQMVIDSGVVP-FLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFP 332
Query: 570 GLLSGSTENVCEQAVWALGNIAGDSPYCRDIVLAAGVSPTL 692
LLS E + ++AVW L NI + V+ AG+ P +
Sbjct: 333 NLLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMI 373
Score = 49.2 bits (112), Expect = 1e-05
Identities = 32/101 (31%), Positives = 51/101 (50%)
Frame = +3
Query: 378 SKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAV 557
+K+P PP++ V + I+P L H + + + WAL+ + G + Q ++V+D G V
Sbjct: 230 NKDPPPPMETVQE--ILPALC-VLIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVV 286
Query: 558 NVLVGLLSGSTENVCEQAVWALGNIAGDSPYCRDIVLAAGV 680
LV LLS V A+ A+GNI + +VL V
Sbjct: 287 PFLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDV 327
Score = 44.0 bits (99), Expect = 5e-04
Identities = 18/62 (29%), Positives = 34/62 (54%)
Frame = +3
Query: 447 LTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWALG 626
L +H + EA W L+NI +G+ Q + V+D G + +++ L+ ++A WA+
Sbjct: 334 LLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAIS 393
Query: 627 NI 632
N+
Sbjct: 394 NL 395
Score = 30.3 bits (65), Expect = 7.0
Identities = 21/97 (21%), Positives = 36/97 (37%)
Frame = +3
Query: 402 DAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLS 581
D VI G+V + F++ T W + N+ + + L L+
Sbjct: 193 DYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPALCVLIY 252
Query: 582 GSTENVCEQAVWALGNIAGDSPYCRDIVLAAGVSPTL 692
+ N+ VWAL + +V+ +GV P L
Sbjct: 253 HTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFL 289
>BC017355-1|AAH17355.1| 521|Homo sapiens karyopherin alpha 3
(importin alpha 4) protein.
Length = 521
Score = 172 bits (418), Expect = 1e-42
Identities = 91/189 (48%), Positives = 118/189 (62%)
Frame = +3
Query: 114 YKNVGLSADELRRRREEEGVQLRKQKREQQLFKRRNVNLPGTNAAGAASQEDINISPSDC 293
+KN G + +RR R E V+LRK KR++ L K+RNV P + S D + +
Sbjct: 15 FKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNV--PQEESL-EDSDVDADFKAQNV 71
Query: 294 ITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTL 473
++ DNP Q+ A Q RKLLS + NPPID +I+SGI+P ++ L NP+L
Sbjct: 72 TLEAILQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNPSL 131
Query: 474 QFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWALGNIAGDSPYC 653
QFEAAWALTNIASG+S QT+ VV AV + + LL +NVCEQAVWALGNI GD P C
Sbjct: 132 QFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGPQC 191
Query: 654 RDIVLAAGV 680
RD V++ GV
Sbjct: 192 RDYVISLGV 200
Score = 58.4 bits (135), Expect = 2e-08
Identities = 34/101 (33%), Positives = 55/101 (54%)
Frame = +3
Query: 390 NPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLV 569
N I VI SG+VP F+ L +H+ +Q A A+ NI +G+ QT++V++ ++
Sbjct: 274 NEQIQMVIDSGVVP-FLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFP 332
Query: 570 GLLSGSTENVCEQAVWALGNIAGDSPYCRDIVLAAGVSPTL 692
LLS E + ++AVW L NI + V+ AG+ P +
Sbjct: 333 NLLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMI 373
Score = 49.2 bits (112), Expect = 1e-05
Identities = 32/101 (31%), Positives = 51/101 (50%)
Frame = +3
Query: 378 SKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAV 557
+K+P PP++ V + I+P L H + + + WAL+ + G + Q ++V+D G V
Sbjct: 230 NKDPPPPMETVQE--ILPALC-VLIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVV 286
Query: 558 NVLVGLLSGSTENVCEQAVWALGNIAGDSPYCRDIVLAAGV 680
LV LLS V A+ A+GNI + +VL V
Sbjct: 287 PFLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDV 327
Score = 44.0 bits (99), Expect = 5e-04
Identities = 18/62 (29%), Positives = 34/62 (54%)
Frame = +3
Query: 447 LTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWALG 626
L +H + EA W L+NI +G+ Q + V+D G + +++ L+ ++A WA+
Sbjct: 334 LLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAIS 393
Query: 627 NI 632
N+
Sbjct: 394 NL 395
Score = 30.3 bits (65), Expect = 7.0
Identities = 21/97 (21%), Positives = 36/97 (37%)
Frame = +3
Query: 402 DAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLS 581
D VI G+V + F++ T W + N+ + + L L+
Sbjct: 193 DYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPALCVLIY 252
Query: 582 GSTENVCEQAVWALGNIAGDSPYCRDIVLAAGVSPTL 692
+ N+ VWAL + +V+ +GV P L
Sbjct: 253 HTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFL 289
>AL136301-1|CAH71145.1| 521|Homo sapiens karyopherin alpha 3
(importin alpha 4) protein.
Length = 521
Score = 172 bits (418), Expect = 1e-42
Identities = 91/189 (48%), Positives = 118/189 (62%)
Frame = +3
Query: 114 YKNVGLSADELRRRREEEGVQLRKQKREQQLFKRRNVNLPGTNAAGAASQEDINISPSDC 293
+KN G + +RR R E V+LRK KR++ L K+RNV P + S D + +
Sbjct: 15 FKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNV--PQEESL-EDSDVDADFKAQNV 71
Query: 294 ITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTL 473
++ DNP Q+ A Q RKLLS + NPPID +I+SGI+P ++ L NP+L
Sbjct: 72 TLEAILQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNPSL 131
Query: 474 QFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWALGNIAGDSPYC 653
QFEAAWALTNIASG+S QT+ VV AV + + LL +NVCEQAVWALGNI GD P C
Sbjct: 132 QFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGPQC 191
Query: 654 RDIVLAAGV 680
RD V++ GV
Sbjct: 192 RDYVISLGV 200
Score = 58.4 bits (135), Expect = 2e-08
Identities = 34/101 (33%), Positives = 55/101 (54%)
Frame = +3
Query: 390 NPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLV 569
N I VI SG+VP F+ L +H+ +Q A A+ NI +G+ QT++V++ ++
Sbjct: 274 NEQIQMVIDSGVVP-FLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFP 332
Query: 570 GLLSGSTENVCEQAVWALGNIAGDSPYCRDIVLAAGVSPTL 692
LLS E + ++AVW L NI + V+ AG+ P +
Sbjct: 333 NLLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMI 373
Score = 49.2 bits (112), Expect = 1e-05
Identities = 32/101 (31%), Positives = 51/101 (50%)
Frame = +3
Query: 378 SKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAV 557
+K+P PP++ V + I+P L H + + + WAL+ + G + Q ++V+D G V
Sbjct: 230 NKDPPPPMETVQE--ILPALC-VLIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVV 286
Query: 558 NVLVGLLSGSTENVCEQAVWALGNIAGDSPYCRDIVLAAGV 680
LV LLS V A+ A+GNI + +VL V
Sbjct: 287 PFLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDV 327
Score = 44.0 bits (99), Expect = 5e-04
Identities = 18/62 (29%), Positives = 34/62 (54%)
Frame = +3
Query: 447 LTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWALG 626
L +H + EA W L+NI +G+ Q + V+D G + +++ L+ ++A WA+
Sbjct: 334 LLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAIS 393
Query: 627 NI 632
N+
Sbjct: 394 NL 395
Score = 30.3 bits (65), Expect = 7.0
Identities = 21/97 (21%), Positives = 36/97 (37%)
Frame = +3
Query: 402 DAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLS 581
D VI G+V + F++ T W + N+ + + L L+
Sbjct: 193 DYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPALCVLIY 252
Query: 582 GSTENVCEQAVWALGNIAGDSPYCRDIVLAAGVSPTL 692
+ N+ VWAL + +V+ +GV P L
Sbjct: 253 HTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFL 289
>AL135901-3|CAI40716.1| 521|Homo sapiens karyopherin alpha 3
(importin alpha 4) protein.
Length = 521
Score = 172 bits (418), Expect = 1e-42
Identities = 91/189 (48%), Positives = 118/189 (62%)
Frame = +3
Query: 114 YKNVGLSADELRRRREEEGVQLRKQKREQQLFKRRNVNLPGTNAAGAASQEDINISPSDC 293
+KN G + +RR R E V+LRK KR++ L K+RNV P + S D + +
Sbjct: 15 FKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNV--PQEESL-EDSDVDADFKAQNV 71
Query: 294 ITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTL 473
++ DNP Q+ A Q RKLLS + NPPID +I+SGI+P ++ L NP+L
Sbjct: 72 TLEAILQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNPSL 131
Query: 474 QFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWALGNIAGDSPYC 653
QFEAAWALTNIASG+S QT+ VV AV + + LL +NVCEQAVWALGNI GD P C
Sbjct: 132 QFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGPQC 191
Query: 654 RDIVLAAGV 680
RD V++ GV
Sbjct: 192 RDYVISLGV 200
Score = 58.4 bits (135), Expect = 2e-08
Identities = 34/101 (33%), Positives = 55/101 (54%)
Frame = +3
Query: 390 NPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLV 569
N I VI SG+VP F+ L +H+ +Q A A+ NI +G+ QT++V++ ++
Sbjct: 274 NEQIQMVIDSGVVP-FLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFP 332
Query: 570 GLLSGSTENVCEQAVWALGNIAGDSPYCRDIVLAAGVSPTL 692
LLS E + ++AVW L NI + V+ AG+ P +
Sbjct: 333 NLLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMI 373
Score = 49.2 bits (112), Expect = 1e-05
Identities = 32/101 (31%), Positives = 51/101 (50%)
Frame = +3
Query: 378 SKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAV 557
+K+P PP++ V + I+P L H + + + WAL+ + G + Q ++V+D G V
Sbjct: 230 NKDPPPPMETVQE--ILPALC-VLIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVV 286
Query: 558 NVLVGLLSGSTENVCEQAVWALGNIAGDSPYCRDIVLAAGV 680
LV LLS V A+ A+GNI + +VL V
Sbjct: 287 PFLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDV 327
Score = 44.0 bits (99), Expect = 5e-04
Identities = 18/62 (29%), Positives = 34/62 (54%)
Frame = +3
Query: 447 LTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWALG 626
L +H + EA W L+NI +G+ Q + V+D G + +++ L+ ++A WA+
Sbjct: 334 LLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAIS 393
Query: 627 NI 632
N+
Sbjct: 394 NL 395
Score = 30.3 bits (65), Expect = 7.0
Identities = 21/97 (21%), Positives = 36/97 (37%)
Frame = +3
Query: 402 DAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLS 581
D VI G+V + F++ T W + N+ + + L L+
Sbjct: 193 DYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPALCVLIY 252
Query: 582 GSTENVCEQAVWALGNIAGDSPYCRDIVLAAGVSPTL 692
+ N+ VWAL + +V+ +GV P L
Sbjct: 253 HTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFL 289
>AK223480-1|BAD97200.1| 521|Homo sapiens karyopherin alpha 3
variant protein.
Length = 521
Score = 172 bits (418), Expect = 1e-42
Identities = 91/189 (48%), Positives = 118/189 (62%)
Frame = +3
Query: 114 YKNVGLSADELRRRREEEGVQLRKQKREQQLFKRRNVNLPGTNAAGAASQEDINISPSDC 293
+KN G + +RR R E V+LRK KR++ L K+RNV P + S D + +
Sbjct: 15 FKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNV--PQEKSL-EDSDVDADFKAQNV 71
Query: 294 ITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTL 473
++ DNP Q+ A Q RKLLS + NPPID +I+SGI+P ++ L NP+L
Sbjct: 72 TLEAILQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNPSL 131
Query: 474 QFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWALGNIAGDSPYC 653
QFEAAWALTNIASG+S QT+ VV AV + + LL +NVCEQAVWALGNI GD P C
Sbjct: 132 QFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGPQC 191
Query: 654 RDIVLAAGV 680
RD V++ GV
Sbjct: 192 RDYVISLGV 200
Score = 58.4 bits (135), Expect = 2e-08
Identities = 34/101 (33%), Positives = 55/101 (54%)
Frame = +3
Query: 390 NPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLV 569
N I VI SG+VP F+ L +H+ +Q A A+ NI +G+ QT++V++ ++
Sbjct: 274 NEQIQMVIDSGVVP-FLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFP 332
Query: 570 GLLSGSTENVCEQAVWALGNIAGDSPYCRDIVLAAGVSPTL 692
LLS E + ++AVW L NI + V+ AG+ P +
Sbjct: 333 NLLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMI 373
Score = 49.2 bits (112), Expect = 1e-05
Identities = 32/101 (31%), Positives = 51/101 (50%)
Frame = +3
Query: 378 SKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAV 557
+K+P PP++ V + I+P L H + + + WAL+ + G + Q ++V+D G V
Sbjct: 230 NKDPPPPMETVQE--ILPALC-VLIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVV 286
Query: 558 NVLVGLLSGSTENVCEQAVWALGNIAGDSPYCRDIVLAAGV 680
LV LLS V A+ A+GNI + +VL V
Sbjct: 287 PFLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDV 327
Score = 38.3 bits (85), Expect = 0.026
Identities = 17/62 (27%), Positives = 33/62 (53%)
Frame = +3
Query: 447 LTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWALG 626
L +H + EA W L+NI +G+ Q + V+D G + +++ L+ ++A A+
Sbjct: 334 LLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAARAIS 393
Query: 627 NI 632
N+
Sbjct: 394 NL 395
Score = 30.3 bits (65), Expect = 7.0
Identities = 21/97 (21%), Positives = 36/97 (37%)
Frame = +3
Query: 402 DAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLS 581
D VI G+V + F++ T W + N+ + + L L+
Sbjct: 193 DYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPALCVLIY 252
Query: 582 GSTENVCEQAVWALGNIAGDSPYCRDIVLAAGVSPTL 692
+ N+ VWAL + +V+ +GV P L
Sbjct: 253 HTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFL 289
>AF005263-1|AAQ13404.1| 521|Homo sapiens importin alpha-3 subunit
protein.
Length = 521
Score = 172 bits (418), Expect = 1e-42
Identities = 91/189 (48%), Positives = 118/189 (62%)
Frame = +3
Query: 114 YKNVGLSADELRRRREEEGVQLRKQKREQQLFKRRNVNLPGTNAAGAASQEDINISPSDC 293
+KN G + +RR R E V+LRK KR++ L K+RNV P + S D + +
Sbjct: 15 FKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNV--PQEESL-EDSDVDADFKAQNV 71
Query: 294 ITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTL 473
++ DNP Q+ A Q RKLLS + NPPID +I+SGI+P ++ L NP+L
Sbjct: 72 TLEAILQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNPSL 131
Query: 474 QFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWALGNIAGDSPYC 653
QFEAAWALTNIASG+S QT+ VV AV + + LL +NVCEQAVWALGNI GD P C
Sbjct: 132 QFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGPQC 191
Query: 654 RDIVLAAGV 680
RD V++ GV
Sbjct: 192 RDYVISLGV 200
Score = 58.4 bits (135), Expect = 2e-08
Identities = 34/101 (33%), Positives = 55/101 (54%)
Frame = +3
Query: 390 NPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLV 569
N I VI SG+VP F+ L +H+ +Q A A+ NI +G+ QT++V++ ++
Sbjct: 274 NEQIQMVIDSGVVP-FLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFP 332
Query: 570 GLLSGSTENVCEQAVWALGNIAGDSPYCRDIVLAAGVSPTL 692
LLS E + ++AVW L NI + V+ AG+ P +
Sbjct: 333 NLLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMI 373
Score = 49.2 bits (112), Expect = 1e-05
Identities = 32/101 (31%), Positives = 51/101 (50%)
Frame = +3
Query: 378 SKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAV 557
+K+P PP++ V + I+P L H + + + WAL+ + G + Q ++V+D G V
Sbjct: 230 NKDPPPPMETVQE--ILPALC-VLIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVV 286
Query: 558 NVLVGLLSGSTENVCEQAVWALGNIAGDSPYCRDIVLAAGV 680
LV LLS V A+ A+GNI + +VL V
Sbjct: 287 PFLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDV 327
Score = 44.0 bits (99), Expect = 5e-04
Identities = 18/62 (29%), Positives = 34/62 (54%)
Frame = +3
Query: 447 LTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWALG 626
L +H + EA W L+NI +G+ Q + V+D G + +++ L+ ++A WA+
Sbjct: 334 LLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAIS 393
Query: 627 NI 632
N+
Sbjct: 394 NL 395
Score = 30.3 bits (65), Expect = 7.0
Identities = 21/97 (21%), Positives = 36/97 (37%)
Frame = +3
Query: 402 DAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLS 581
D VI G+V + F++ T W + N+ + + L L+
Sbjct: 193 DYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPALCVLIY 252
Query: 582 GSTENVCEQAVWALGNIAGDSPYCRDIVLAAGVSPTL 692
+ N+ VWAL + +V+ +GV P L
Sbjct: 253 HTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFL 289
>Y12394-1|CAA73026.1| 521|Homo sapiens SRP1-like protein protein.
Length = 521
Score = 171 bits (415), Expect = 3e-42
Identities = 90/189 (47%), Positives = 118/189 (62%)
Frame = +3
Query: 114 YKNVGLSADELRRRREEEGVQLRKQKREQQLFKRRNVNLPGTNAAGAASQEDINISPSDC 293
+KN G + +RR R E ++LRK KR++ L K+RNV P + S D + +
Sbjct: 15 FKNKGRDVETMRRHRNEVTMELRKNKRDEHLLKKRNV--PQEESL-EDSDVDADFKAQNV 71
Query: 294 ITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTL 473
++ DNP Q+ A Q RKLLS + NPPID +I+SGI+P ++ L NP+L
Sbjct: 72 TLEAILQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNPSL 131
Query: 474 QFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWALGNIAGDSPYC 653
QFEAAWALTNIASG+S QT+ VV AV + + LL +NVCEQAVWALGNI GD P C
Sbjct: 132 QFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGPQC 191
Query: 654 RDIVLAAGV 680
RD V++ GV
Sbjct: 192 RDYVISLGV 200
Score = 58.8 bits (136), Expect = 2e-08
Identities = 40/133 (30%), Positives = 66/133 (49%)
Frame = +3
Query: 294 ITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTL 473
I P + + +Y V+ T L+ N I VI SG+VP F+ L +H+ +
Sbjct: 243 ILPALCVLIY-HTDVNIVVDTVWALSYLTDGGNEQIQMVIDSGVVP-FLVPLLSHQEVKV 300
Query: 474 QFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWALGNIAGDSPYC 653
Q A A+ NI +G+ QT++V++ ++ LLS E + ++AVW L NI +
Sbjct: 301 QTAALRAVGNIVTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNITAGNQQQ 360
Query: 654 RDIVLAAGVSPTL 692
V+ AG+ P +
Sbjct: 361 VQAVIDAGLIPMI 373
Score = 44.0 bits (99), Expect = 5e-04
Identities = 18/62 (29%), Positives = 34/62 (54%)
Frame = +3
Query: 447 LTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWALG 626
L +H + EA W L+NI +G+ Q + V+D G + +++ L+ ++A WA+
Sbjct: 334 LLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAIS 393
Query: 627 NI 632
N+
Sbjct: 394 NL 395
Score = 31.1 bits (67), Expect = 4.0
Identities = 21/97 (21%), Positives = 36/97 (37%)
Frame = +3
Query: 402 DAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLS 581
D VI G+V + F++ T W + N+ + + L L+
Sbjct: 193 DYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPLETVQEILPALCVLIY 252
Query: 582 GSTENVCEQAVWALGNIAGDSPYCRDIVLAAGVSPTL 692
+ N+ VWAL + +V+ +GV P L
Sbjct: 253 HTDVNIVVDTVWALSYLTDGGNEQIQMVIDSGVVPFL 289
>BC035090-1|AAH35090.1| 521|Homo sapiens karyopherin alpha 3
(importin alpha 4) protein.
Length = 521
Score = 171 bits (415), Expect = 3e-42
Identities = 90/189 (47%), Positives = 118/189 (62%)
Frame = +3
Query: 114 YKNVGLSADELRRRREEEGVQLRKQKREQQLFKRRNVNLPGTNAAGAASQEDINISPSDC 293
+KN G + +RR R E V+LRK KR++ L K+RNV P + S D + +
Sbjct: 15 FKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNV--PQEESL-EDSDVDADFKAQNV 71
Query: 294 ITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTL 473
++ DNP Q+ A Q RKLLS + NPPID +I+SGI+P ++ L NP+L
Sbjct: 72 TLEAILQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNPSL 131
Query: 474 QFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWALGNIAGDSPYC 653
QFEAAWALTNIASG+S QT+ +V AV + + LL +NVCEQAVWALGNI GD P C
Sbjct: 132 QFEAAWALTNIASGTSAQTQDIVQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGPQC 191
Query: 654 RDIVLAAGV 680
RD V++ GV
Sbjct: 192 RDYVISLGV 200
Score = 58.4 bits (135), Expect = 2e-08
Identities = 34/101 (33%), Positives = 55/101 (54%)
Frame = +3
Query: 390 NPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLV 569
N I VI SG+VP F+ L +H+ +Q A A+ NI +G+ QT++V++ ++
Sbjct: 274 NEQIQMVIDSGVVP-FLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFQ 332
Query: 570 GLLSGSTENVCEQAVWALGNIAGDSPYCRDIVLAAGVSPTL 692
LLS E + ++AVW L NI + V+ AG+ P +
Sbjct: 333 NLLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMI 373
Score = 49.2 bits (112), Expect = 1e-05
Identities = 32/101 (31%), Positives = 51/101 (50%)
Frame = +3
Query: 378 SKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAV 557
+K+P PP++ V + I+P L H + + + WAL+ + G + Q ++V+D G V
Sbjct: 230 NKDPPPPMETVQE--ILPALC-VLIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVV 286
Query: 558 NVLVGLLSGSTENVCEQAVWALGNIAGDSPYCRDIVLAAGV 680
LV LLS V A+ A+GNI + +VL V
Sbjct: 287 PFLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDV 327
Score = 44.0 bits (99), Expect = 5e-04
Identities = 18/62 (29%), Positives = 34/62 (54%)
Frame = +3
Query: 447 LTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWALG 626
L +H + EA W L+NI +G+ Q + V+D G + +++ L+ ++A WA+
Sbjct: 334 LLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAIS 393
Query: 627 NI 632
N+
Sbjct: 394 NL 395
Score = 30.3 bits (65), Expect = 7.0
Identities = 21/97 (21%), Positives = 36/97 (37%)
Frame = +3
Query: 402 DAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLS 581
D VI G+V + F++ T W + N+ + + L L+
Sbjct: 193 DYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPALCVLIY 252
Query: 582 GSTENVCEQAVWALGNIAGDSPYCRDIVLAAGVSPTL 692
+ N+ VWAL + +V+ +GV P L
Sbjct: 253 HTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFL 289
>AF034756-1|AAB87693.1| 521|Homo sapiens importin-alpha homolog
protein.
Length = 521
Score = 169 bits (411), Expect = 8e-42
Identities = 90/189 (47%), Positives = 117/189 (61%)
Frame = +3
Query: 114 YKNVGLSADELRRRREEEGVQLRKQKREQQLFKRRNVNLPGTNAAGAASQEDINISPSDC 293
+KN G + +RR R E V+LRK KR++ L K+RNV P + S D + +
Sbjct: 15 FKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNV--PQEESL-EDSDVDADFKAQNV 71
Query: 294 ITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTL 473
++ DNP Q+ A Q RKLLS + NPPID +I+SGI+P ++ L NP+L
Sbjct: 72 TLEAILQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNPSL 131
Query: 474 QFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWALGNIAGDSPYC 653
QFEAAWALTNIASG+S QT+ V AV + + LL +NVCEQAVWALGNI GD P C
Sbjct: 132 QFEAAWALTNIASGTSAQTQAVGQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGPQC 191
Query: 654 RDIVLAAGV 680
RD V++ GV
Sbjct: 192 RDYVISLGV 200
Score = 58.4 bits (135), Expect = 2e-08
Identities = 34/101 (33%), Positives = 55/101 (54%)
Frame = +3
Query: 390 NPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLV 569
N I VI SG+VP F+ L +H+ +Q A A+ NI +G+ QT++V++ ++
Sbjct: 274 NEQIQMVIDSGVVP-FLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFP 332
Query: 570 GLLSGSTENVCEQAVWALGNIAGDSPYCRDIVLAAGVSPTL 692
LLS E + ++AVW L NI + V+ AG+ P +
Sbjct: 333 NLLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMI 373
Score = 46.0 bits (104), Expect = 1e-04
Identities = 31/101 (30%), Positives = 50/101 (49%)
Frame = +3
Query: 378 SKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAV 557
+K+P P ++ V + I+P L H + + + WAL+ + G + Q ++V+D G V
Sbjct: 230 NKDPPPTMETVQE--ILPALC-VLIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVV 286
Query: 558 NVLVGLLSGSTENVCEQAVWALGNIAGDSPYCRDIVLAAGV 680
LV LLS V A+ A+GNI + +VL V
Sbjct: 287 PFLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDV 327
Score = 44.0 bits (99), Expect = 5e-04
Identities = 18/62 (29%), Positives = 34/62 (54%)
Frame = +3
Query: 447 LTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWALG 626
L +H + EA W L+NI +G+ Q + V+D G + +++ L+ ++A WA+
Sbjct: 334 LLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAIS 393
Query: 627 NI 632
N+
Sbjct: 394 NL 395
Score = 30.7 bits (66), Expect = 5.3
Identities = 21/97 (21%), Positives = 36/97 (37%)
Frame = +3
Query: 402 DAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLS 581
D VI G+V + F++ T W + N+ + + L L+
Sbjct: 193 DYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPTMETVQEILPALCVLIY 252
Query: 582 GSTENVCEQAVWALGNIAGDSPYCRDIVLAAGVSPTL 692
+ N+ VWAL + +V+ +GV P L
Sbjct: 253 HTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFL 289
>U93240-1|AAC25605.1| 521|Homo sapiens importin alpha 3 protein.
Length = 521
Score = 166 bits (403), Expect = 8e-41
Identities = 92/189 (48%), Positives = 117/189 (61%)
Frame = +3
Query: 114 YKNVGLSADELRRRREEEGVQLRKQKREQQLFKRRNVNLPGTNAAGAASQEDINISPSDC 293
+KN G + +RR+R E V+LRK KR++ L KRRNV P + S D + +
Sbjct: 15 FKNKGRDLETMRRQRNEVVVELRKNKRDEHLLKRRNV--PHEDIC-EDSDIDGDYRVQNT 71
Query: 294 ITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTL 473
+V DN Q+ A Q RKLLS + NPPID +I+SGI+P + L NP+L
Sbjct: 72 SLEAIVQNASSDNQGIQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVHCLERDDNPSL 131
Query: 474 QFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWALGNIAGDSPYC 653
QFEAAWALTNIASG+S QT+ VV AV + + LL +NVCEQAVWALGNI GD P C
Sbjct: 132 QFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQC 191
Query: 654 RDIVLAAGV 680
RD V++ GV
Sbjct: 192 RDYVISLGV 200
Score = 46.0 bits (104), Expect = 1e-04
Identities = 29/96 (30%), Positives = 49/96 (51%)
Frame = +3
Query: 381 KEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVN 560
K+P PP++ + + I+P L +H + + + WAL+ + + Q ++V+D G V
Sbjct: 231 KDPPPPMETIQE--ILPALC-VLIHHTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVP 287
Query: 561 VLVGLLSGSTENVCEQAVWALGNIAGDSPYCRDIVL 668
LV LLS V A+ A+GNI + +VL
Sbjct: 288 HLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVL 323
Score = 44.4 bits (100), Expect = 4e-04
Identities = 30/126 (23%), Positives = 54/126 (42%)
Frame = +3
Query: 255 ASQEDINISPSDCITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQSGIVPK 434
A E I + I P +V + + Q A + +++ + V+ +
Sbjct: 272 AGNEQIQMVIDSGIVPHLVPLLSHQEVKVQTAALRAVGNIVTGT-DEQTQVVLNCDALSH 330
Query: 435 FIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAV 614
F LT H + EA W L+NI +G+ Q + V+D V +++ LL ++A
Sbjct: 331 FPALLT-HPKEKINKEAVWFLSNITAGNQQQVQAVIDANLVPMIIHLLDKGDFGTQKEAA 389
Query: 615 WALGNI 632
WA+ N+
Sbjct: 390 WAISNL 395
>BC034493-1|AAH34493.1| 521|Homo sapiens karyopherin alpha 4
(importin alpha 3) protein.
Length = 521
Score = 166 bits (403), Expect = 8e-41
Identities = 92/189 (48%), Positives = 117/189 (61%)
Frame = +3
Query: 114 YKNVGLSADELRRRREEEGVQLRKQKREQQLFKRRNVNLPGTNAAGAASQEDINISPSDC 293
+KN G + +RR+R E V+LRK KR++ L KRRNV P + S D + +
Sbjct: 15 FKNKGRDLETMRRQRNEVVVELRKNKRDEHLLKRRNV--PHEDIC-EDSDIDGDYRVQNT 71
Query: 294 ITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTL 473
+V DN Q+ A Q RKLLS + NPPID +I+SGI+P + L NP+L
Sbjct: 72 SLEAIVQNASSDNQGIQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVHCLERDDNPSL 131
Query: 474 QFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWALGNIAGDSPYC 653
QFEAAWALTNIASG+S QT+ VV AV + + LL +NVCEQAVWALGNI GD P C
Sbjct: 132 QFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQC 191
Query: 654 RDIVLAAGV 680
RD V++ GV
Sbjct: 192 RDYVISLGV 200
Score = 46.0 bits (104), Expect = 1e-04
Identities = 29/96 (30%), Positives = 49/96 (51%)
Frame = +3
Query: 381 KEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVN 560
K+P PP++ + + I+P L +H + + + WAL+ + + Q ++V+D G V
Sbjct: 231 KDPPPPMETIQE--ILPALC-VLIHHTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVP 287
Query: 561 VLVGLLSGSTENVCEQAVWALGNIAGDSPYCRDIVL 668
LV LLS V A+ A+GNI + +VL
Sbjct: 288 HLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVL 323
Score = 44.4 bits (100), Expect = 4e-04
Identities = 30/126 (23%), Positives = 54/126 (42%)
Frame = +3
Query: 255 ASQEDINISPSDCITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQSGIVPK 434
A E I + I P +V + + Q A + +++ + V+ +
Sbjct: 272 AGNEQIQMVIDSGIVPHLVPLLSHQEVKVQTAALRAVGNIVTGT-DEQTQVVLNCDALSH 330
Query: 435 FIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAV 614
F LT H + EA W L+NI +G+ Q + V+D V +++ LL ++A
Sbjct: 331 FPALLT-HPKEKINKEAVWFLSNITAGNQQQVQAVIDANLVPMIIHLLDKGDFGTQKEAA 389
Query: 615 WALGNI 632
WA+ N+
Sbjct: 390 WAISNL 395
>BC028691-1|AAH28691.1| 521|Homo sapiens karyopherin alpha 4
(importin alpha 3) protein.
Length = 521
Score = 166 bits (403), Expect = 8e-41
Identities = 92/189 (48%), Positives = 117/189 (61%)
Frame = +3
Query: 114 YKNVGLSADELRRRREEEGVQLRKQKREQQLFKRRNVNLPGTNAAGAASQEDINISPSDC 293
+KN G + +RR+R E V+LRK KR++ L KRRNV P + S D + +
Sbjct: 15 FKNKGRDLETMRRQRNEVVVELRKNKRDEHLLKRRNV--PHEDIC-EDSDIDGDYRVQNT 71
Query: 294 ITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTL 473
+V DN Q+ A Q RKLLS + NPPID +I+SGI+P + L NP+L
Sbjct: 72 SLEAIVQNASSDNQGIQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVHCLERDDNPSL 131
Query: 474 QFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWALGNIAGDSPYC 653
QFEAAWALTNIASG+S QT+ VV AV + + LL +NVCEQAVWALGNI GD P C
Sbjct: 132 QFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQC 191
Query: 654 RDIVLAAGV 680
RD V++ GV
Sbjct: 192 RDYVISLGV 200
Score = 46.0 bits (104), Expect = 1e-04
Identities = 29/96 (30%), Positives = 49/96 (51%)
Frame = +3
Query: 381 KEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVN 560
K+P PP++ + + I+P L +H + + + WAL+ + + Q ++V+D G V
Sbjct: 231 KDPPPPMETIQE--ILPALC-VLIHHTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVP 287
Query: 561 VLVGLLSGSTENVCEQAVWALGNIAGDSPYCRDIVL 668
LV LLS V A+ A+GNI + +VL
Sbjct: 288 HLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVL 323
Score = 44.4 bits (100), Expect = 4e-04
Identities = 30/126 (23%), Positives = 54/126 (42%)
Frame = +3
Query: 255 ASQEDINISPSDCITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQSGIVPK 434
A E I + I P +V + + Q A + +++ + V+ +
Sbjct: 272 AGNEQIQMVIDSGIVPHLVPLLSHQEVKVQTAALRAVGNIVTGT-DEQTQVVLNCDALSH 330
Query: 435 FIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAV 614
F LT H + EA W L+NI +G+ Q + V+D V +++ LL ++A
Sbjct: 331 FPALLT-HPKEKINKEAVWFLSNITAGNQQQVQAVIDANLVPMIIHLLDKGDFGTQKEAA 389
Query: 615 WALGNI 632
WA+ N+
Sbjct: 390 WAISNL 395
>AB002533-1|BAA19546.1| 521|Homo sapiens Qip1 protein.
Length = 521
Score = 166 bits (403), Expect = 8e-41
Identities = 92/189 (48%), Positives = 117/189 (61%)
Frame = +3
Query: 114 YKNVGLSADELRRRREEEGVQLRKQKREQQLFKRRNVNLPGTNAAGAASQEDINISPSDC 293
+KN G + +RR+R E V+LRK KR++ L KRRNV P + S D + +
Sbjct: 15 FKNKGRDLETMRRQRNEVVVELRKNKRDEHLLKRRNV--PHEDIC-EDSDIDGDYRVQNT 71
Query: 294 ITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTL 473
+V DN Q+ A Q RKLLS + NPPID +I+SGI+P + L NP+L
Sbjct: 72 SLEAIVQNASSDNQGIQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVHCLERDDNPSL 131
Query: 474 QFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWALGNIAGDSPYC 653
QFEAAWALTNIASG+S QT+ VV AV + + LL +NVCEQAVWALGNI GD P C
Sbjct: 132 QFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQC 191
Query: 654 RDIVLAAGV 680
RD V++ GV
Sbjct: 192 RDYVISLGV 200
Score = 46.0 bits (104), Expect = 1e-04
Identities = 29/96 (30%), Positives = 49/96 (51%)
Frame = +3
Query: 381 KEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVN 560
K+P PP++ + + I+P L +H + + + WAL+ + + Q ++V+D G V
Sbjct: 231 KDPPPPMETIQE--ILPALC-VLIHHTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVP 287
Query: 561 VLVGLLSGSTENVCEQAVWALGNIAGDSPYCRDIVL 668
LV LLS V A+ A+GNI + +VL
Sbjct: 288 HLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVL 323
Score = 44.4 bits (100), Expect = 4e-04
Identities = 30/126 (23%), Positives = 54/126 (42%)
Frame = +3
Query: 255 ASQEDINISPSDCITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQSGIVPK 434
A E I + I P +V + + Q A + +++ + V+ +
Sbjct: 272 AGNEQIQMVIDSGIVPHLVPLLSHQEVKVQTAALRAVGNIVTGT-DEQTQVVLNCDALSH 330
Query: 435 FIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAV 614
F LT H + EA W L+NI +G+ Q + V+D V +++ LL ++A
Sbjct: 331 FPALLT-HPKEKINKEAVWFLSNITAGNQQQVQAVIDANLVPMIIHLLDKGDFGTQKEAA 389
Query: 615 WALGNI 632
WA+ N+
Sbjct: 390 WAISNL 395
>AL132795-6|CAI20501.1| 142|Homo sapiens karyopherin alpha 5
(importin alpha 6) protein.
Length = 142
Score = 135 bits (326), Expect = 2e-31
Identities = 71/129 (55%), Positives = 94/129 (72%), Gaps = 8/129 (6%)
Frame = +3
Query: 114 YKNVGLSADELRRRREEEGVQLRKQKREQQLFKRRNVNLPGTNAAGAASQ-EDINISPS- 287
YKN L+ E+RRRREEEG+QLRKQKRE+QLFKRRNV LP + + S +D +IS +
Sbjct: 14 YKNKALNPQEMRRRREEEGIQLRKQKREEQLFKRRNVYLPRNDESMLESPIQDPDISSTV 73
Query: 288 -----DCITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQS-GIVPKFIEFL 449
+ +T DMV ++ +N ++Q+ ATQKFRKLLSKEPNPPID VIQ G+V +F++FL
Sbjct: 74 PIPEEEVVTTDMVQMIFSNNADQQLTATQKFRKLLSKEPNPPIDQVIQKPGVVQRFVKFL 133
Query: 450 TNHKNPTLQ 476
++N TLQ
Sbjct: 134 ERNENCTLQ 142
>AL049795-1|CAI22054.1| 321|Homo sapiens karyopherin alpha 6
(importin alpha 7) protein.
Length = 321
Score = 97.1 bits (231), Expect = 5e-20
Identities = 67/152 (44%), Positives = 90/152 (59%), Gaps = 7/152 (4%)
Frame = +3
Query: 213 RRNVNLPGTNAAGAASQ-EDINISPS---DCITPDMVLAVYLDNPEEQVIATQKFRKLLS 380
RRNV L AA S D +S + IT +MV ++ D+ + Q+ TQKFRKLLS
Sbjct: 1 RRNVELINEEAAMFDSLLMDSYVSSTTGESVITREMVEMLFSDDSDLQLATTQKFRKLLS 60
Query: 381 KEPNPPIDAVIQS-GIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAV 557
KEP+PPID VI + +V +F+EFL ++N TLQ A WAL NIA SS V++ +
Sbjct: 61 KEPSPPIDEVINTPRVVDRFVEFLKRNENCTLQ--AVWALGNIAGDSSVCRDYVLNCSIL 118
Query: 558 NVLVGLLSGSTE-NVCEQAVWALGNIA-GDSP 647
N L+ LL+ ST + AVWAL N+ G +P
Sbjct: 119 NPLLTLLTKSTRLTMTRNAVWALSNLCRGKNP 150
Score = 59.7 bits (138), Expect = 1e-08
Identities = 34/106 (32%), Positives = 56/106 (52%)
Frame = +3
Query: 375 LSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGA 554
LS PN I AVI SG+ + +E L H + + A A+ NI +G QT+++++ A
Sbjct: 186 LSDGPNEKIQAVIDSGVCRRLVELLM-HNDYKVASPALRAVGNIVTGDDIQTQVILNCSA 244
Query: 555 VNVLVGLLSGSTENVCEQAVWALGNIAGDSPYCRDIVLAAGVSPTL 692
+ L+ LLS E++ ++A W + NI + V+ A + P L
Sbjct: 245 LPCLLHLLSSPKESIRKEACWTISNITAGNRAQIQAVIDANIFPVL 290
Score = 44.4 bits (100), Expect = 4e-04
Identities = 20/30 (66%), Positives = 21/30 (70%)
Frame = +3
Query: 591 ENVCEQAVWALGNIAGDSPYCRDIVLAAGV 680
EN QAVWALGNIAGDS CRD VL +
Sbjct: 88 ENCTLQAVWALGNIAGDSSVCRDYVLNCSI 117
Score = 43.2 bits (97), Expect = 0.001
Identities = 29/106 (27%), Positives = 47/106 (44%)
Frame = +3
Query: 375 LSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGA 554
L + NPP + S +P L + + L +A WAL+ ++ G + + + V+D G
Sbjct: 144 LCRGKNPPPEFAKVSPCLPVLSRLLFSSDSDLLA-DACWALSYLSDGPNEKIQAVIDSGV 202
Query: 555 VNVLVGLLSGSTENVCEQAVWALGNIAGDSPYCRDIVLAAGVSPTL 692
LV LL + V A+ A+GNI ++L P L
Sbjct: 203 CRRLVELLMHNDYKVASPALRAVGNIVTGDDIQTQVILNCSALPCL 248
Score = 43.2 bits (97), Expect = 0.001
Identities = 21/81 (25%), Positives = 44/81 (54%), Gaps = 1/81 (1%)
Frame = +3
Query: 408 VIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGS 587
++ +P + L++ K +++ EA W ++NI +G+ Q + V+D VL+ +L +
Sbjct: 239 ILNCSALPCLLHLLSSPKE-SIRKEACWTISNITAGNRAQIQAVIDANIFPVLIEILQKA 297
Query: 588 TENVCEQAVWALGN-IAGDSP 647
++A WA+ N +G +P
Sbjct: 298 EFRTRKEAAWAITNATSGGTP 318
>Y12393-1|CAA73025.1| 281|Homo sapiens SRP1-like protein protein.
Length = 281
Score = 44.4 bits (100), Expect = 4e-04
Identities = 30/126 (23%), Positives = 54/126 (42%)
Frame = +3
Query: 255 ASQEDINISPSDCITPDMVLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQSGIVPK 434
A E I + I P +V + + Q A + +++ + V+ +
Sbjct: 32 AGNEQIQMVIDSGIVPHLVPLLSHQEVKVQTAALRAVGNIVTGT-DEQTQVVLNCDALSH 90
Query: 435 FIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAV 614
F LT H + EA W L+NI +G+ Q + V+D V +++ LL ++A
Sbjct: 91 FPALLT-HPKEKINKEAVWFLSNITAGNQQQVQAVIDANLVPMIIHLLDKGDFGTQKEAA 149
Query: 615 WALGNI 632
WA+ N+
Sbjct: 150 WAISNL 155
Score = 39.5 bits (88), Expect = 0.011
Identities = 23/74 (31%), Positives = 37/74 (50%)
Frame = +3
Query: 447 LTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWALG 626
L +H + + + WAL+ + + Q ++V+D G V LV LLS V A+ A+G
Sbjct: 10 LIHHTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLLSHQEVKVQTAALRAVG 69
Query: 627 NIAGDSPYCRDIVL 668
NI + +VL
Sbjct: 70 NIVTGTDEQTQVVL 83
>BC030585-1|AAH30585.1| 458|Homo sapiens sperm associated antigen 6
protein.
Length = 458
Score = 42.7 bits (96), Expect = 0.001
Identities = 30/97 (30%), Positives = 46/97 (47%)
Frame = +3
Query: 402 DAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLS 581
+AV++ I+P+ + L +N + AA+ L + S + +VD GA++ LV L
Sbjct: 77 EAVVKCDILPQLVYSLAE-QNRFYKKAAAFVLRAVGKHSPQLAQAIVDCGALDTLVICLE 135
Query: 582 GSTENVCEQAVWALGNIAGDSPYCRDIVLAAGVSPTL 692
V E A WAL IA + V+ AG P L
Sbjct: 136 DFDPGVKEAAAWALRYIARHNAELSQAVVDAGAVPLL 172
Score = 37.1 bits (82), Expect = 0.061
Identities = 30/97 (30%), Positives = 47/97 (48%)
Frame = +3
Query: 405 AVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSG 584
A++ G + + L + +P ++ AAWAL IA ++ ++ VVD GAV +LV +
Sbjct: 120 AIVDCGALDTLVICLEDF-DPGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQE 178
Query: 585 STENVCEQAVWALGNIAGDSPYCRDIVLAAGVSPTLA 695
+ A AL +I SP V+ AG LA
Sbjct: 179 PEIALKGIAASALSDIVKHSPELAQTVVDAGAVAHLA 215
Score = 33.5 bits (73), Expect = 0.75
Identities = 26/96 (27%), Positives = 44/96 (45%)
Frame = +3
Query: 405 AVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSG 584
AV+ +G VP + L+ AA AL++I S + VVD GAV L ++
Sbjct: 162 AVVDAGAVPLLV-LCIQEPEIALKGIAASALSDIVKHSPELAQTVVDAGAVAHLAQMILN 220
Query: 585 STENVCEQAVWALGNIAGDSPYCRDIVLAAGVSPTL 692
+ Q + AL ++ S ++V+ A + P +
Sbjct: 221 PDAKLKHQILSALSQVSKHSVDLAEMVVEAEIFPVV 256
>AL513128-4|CAH72210.1| 509|Homo sapiens sperm associated antigen 6
protein.
Length = 509
Score = 42.7 bits (96), Expect = 0.001
Identities = 30/97 (30%), Positives = 46/97 (47%)
Frame = +3
Query: 402 DAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLS 581
+AV++ I+P+ + L +N + AA+ L + S + +VD GA++ LV L
Sbjct: 77 EAVVKCDILPQLVYSLAE-QNRFYKKAAAFVLRAVGKHSPQLAQAIVDCGALDTLVICLE 135
Query: 582 GSTENVCEQAVWALGNIAGDSPYCRDIVLAAGVSPTL 692
V E A WAL IA + V+ AG P L
Sbjct: 136 DFDPGVKEAAAWALRYIARHNAELSQAVVDAGAVPLL 172
Score = 39.5 bits (88), Expect = 0.011
Identities = 31/97 (31%), Positives = 48/97 (49%)
Frame = +3
Query: 405 AVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSG 584
A++ G + + L + +P ++ AAWAL IA ++ ++ VVD GAV +LV +
Sbjct: 120 AIVDCGALDTLVICLEDF-DPGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQE 178
Query: 585 STENVCEQAVWALGNIAGDSPYCRDIVLAAGVSPTLA 695
+ A AL +IA SP V+ AG LA
Sbjct: 179 PEIALKRIAASALSDIAKHSPELAQTVVDAGAVAHLA 215
Score = 35.1 bits (77), Expect = 0.25
Identities = 27/96 (28%), Positives = 45/96 (46%)
Frame = +3
Query: 405 AVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSG 584
AV+ +G VP + L+ AA AL++IA S + VVD GAV L ++
Sbjct: 162 AVVDAGAVPLLV-LCIQEPEIALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMILN 220
Query: 585 STENVCEQAVWALGNIAGDSPYCRDIVLAAGVSPTL 692
+ Q + AL ++ S ++V+ A + P +
Sbjct: 221 PDAKLKHQILSALSQVSKHSVDLAEMVVEAEIFPVV 256
>AL513128-3|CAH72209.1| 458|Homo sapiens sperm associated antigen 6
protein.
Length = 458
Score = 42.7 bits (96), Expect = 0.001
Identities = 30/97 (30%), Positives = 46/97 (47%)
Frame = +3
Query: 402 DAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLS 581
+AV++ I+P+ + L +N + AA+ L + S + +VD GA++ LV L
Sbjct: 77 EAVVKCDILPQLVYSLAE-QNRFYKKAAAFVLRAVGKHSPQLAQAIVDCGALDTLVICLE 135
Query: 582 GSTENVCEQAVWALGNIAGDSPYCRDIVLAAGVSPTL 692
V E A WAL IA + V+ AG P L
Sbjct: 136 DFDPGVKEAAAWALRYIARHNAELSQAVVDAGAVPLL 172
Score = 39.5 bits (88), Expect = 0.011
Identities = 31/97 (31%), Positives = 48/97 (49%)
Frame = +3
Query: 405 AVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSG 584
A++ G + + L + +P ++ AAWAL IA ++ ++ VVD GAV +LV +
Sbjct: 120 AIVDCGALDTLVICLEDF-DPGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQE 178
Query: 585 STENVCEQAVWALGNIAGDSPYCRDIVLAAGVSPTLA 695
+ A AL +IA SP V+ AG LA
Sbjct: 179 PEIALKRIAASALSDIAKHSPELAQTVVDAGAVAHLA 215
Score = 35.1 bits (77), Expect = 0.25
Identities = 27/96 (28%), Positives = 45/96 (46%)
Frame = +3
Query: 405 AVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSG 584
AV+ +G VP + L+ AA AL++IA S + VVD GAV L ++
Sbjct: 162 AVVDAGAVPLLV-LCIQEPEIALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMILN 220
Query: 585 STENVCEQAVWALGNIAGDSPYCRDIVLAAGVSPTL 692
+ Q + AL ++ S ++V+ A + P +
Sbjct: 221 PDAKLKHQILSALSQVSKHSVDLAEMVVEAEIFPVV 256
>AL158211-15|CAI15963.1| 509|Homo sapiens sperm associated antigen
6 protein.
Length = 509
Score = 42.7 bits (96), Expect = 0.001
Identities = 30/97 (30%), Positives = 46/97 (47%)
Frame = +3
Query: 402 DAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLS 581
+AV++ I+P+ + L +N + AA+ L + S + +VD GA++ LV L
Sbjct: 77 EAVVKCDILPQLVYSLAE-QNRFYKKAAAFVLRAVGKHSPQLAQAIVDCGALDTLVICLE 135
Query: 582 GSTENVCEQAVWALGNIAGDSPYCRDIVLAAGVSPTL 692
V E A WAL IA + V+ AG P L
Sbjct: 136 DFDPGVKEAAAWALRYIARHNAELSQAVVDAGAVPLL 172
Score = 39.5 bits (88), Expect = 0.011
Identities = 31/97 (31%), Positives = 48/97 (49%)
Frame = +3
Query: 405 AVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSG 584
A++ G + + L + +P ++ AAWAL IA ++ ++ VVD GAV +LV +
Sbjct: 120 AIVDCGALDTLVICLEDF-DPGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQE 178
Query: 585 STENVCEQAVWALGNIAGDSPYCRDIVLAAGVSPTLA 695
+ A AL +IA SP V+ AG LA
Sbjct: 179 PEIALKRIAASALSDIAKHSPELAQTVVDAGAVAHLA 215
Score = 35.1 bits (77), Expect = 0.25
Identities = 27/96 (28%), Positives = 45/96 (46%)
Frame = +3
Query: 405 AVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSG 584
AV+ +G VP + L+ AA AL++IA S + VVD GAV L ++
Sbjct: 162 AVVDAGAVPLLV-LCIQEPEIALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMILN 220
Query: 585 STENVCEQAVWALGNIAGDSPYCRDIVLAAGVSPTL 692
+ Q + AL ++ S ++V+ A + P +
Sbjct: 221 PDAKLKHQILSALSQVSKHSVDLAEMVVEAEIFPVV 256
>AL158211-14|CAI15962.1| 458|Homo sapiens sperm associated antigen
6 protein.
Length = 458
Score = 42.7 bits (96), Expect = 0.001
Identities = 30/97 (30%), Positives = 46/97 (47%)
Frame = +3
Query: 402 DAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLS 581
+AV++ I+P+ + L +N + AA+ L + S + +VD GA++ LV L
Sbjct: 77 EAVVKCDILPQLVYSLAE-QNRFYKKAAAFVLRAVGKHSPQLAQAIVDCGALDTLVICLE 135
Query: 582 GSTENVCEQAVWALGNIAGDSPYCRDIVLAAGVSPTL 692
V E A WAL IA + V+ AG P L
Sbjct: 136 DFDPGVKEAAAWALRYIARHNAELSQAVVDAGAVPLL 172
Score = 39.5 bits (88), Expect = 0.011
Identities = 31/97 (31%), Positives = 48/97 (49%)
Frame = +3
Query: 405 AVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSG 584
A++ G + + L + +P ++ AAWAL IA ++ ++ VVD GAV +LV +
Sbjct: 120 AIVDCGALDTLVICLEDF-DPGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQE 178
Query: 585 STENVCEQAVWALGNIAGDSPYCRDIVLAAGVSPTLA 695
+ A AL +IA SP V+ AG LA
Sbjct: 179 PEIALKRIAASALSDIAKHSPELAQTVVDAGAVAHLA 215
Score = 35.1 bits (77), Expect = 0.25
Identities = 27/96 (28%), Positives = 45/96 (46%)
Frame = +3
Query: 405 AVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSG 584
AV+ +G VP + L+ AA AL++IA S + VVD GAV L ++
Sbjct: 162 AVVDAGAVPLLV-LCIQEPEIALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMILN 220
Query: 585 STENVCEQAVWALGNIAGDSPYCRDIVLAAGVSPTL 692
+ Q + AL ++ S ++V+ A + P +
Sbjct: 221 PDAKLKHQILSALSQVSKHSVDLAEMVVEAEIFPVV 256
>AF079363-1|AAC32590.1| 509|Homo sapiens sperm flagellar protein
Repro-SA-1 protein.
Length = 509
Score = 42.7 bits (96), Expect = 0.001
Identities = 30/97 (30%), Positives = 46/97 (47%)
Frame = +3
Query: 402 DAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLS 581
+AV++ I+P+ + L +N + AA+ L + S + +VD GA++ LV L
Sbjct: 77 EAVVKCDILPQLVYSLAE-QNRFYKKAAAFVLRAVGKHSPQLAQAIVDCGALDTLVICLE 135
Query: 582 GSTENVCEQAVWALGNIAGDSPYCRDIVLAAGVSPTL 692
V E A WAL IA + V+ AG P L
Sbjct: 136 DFDPGVKEAAAWALRYIARHNAELSQAVVDAGAVPLL 172
Score = 39.5 bits (88), Expect = 0.011
Identities = 31/97 (31%), Positives = 48/97 (49%)
Frame = +3
Query: 405 AVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSG 584
A++ G + + L + +P ++ AAWAL IA ++ ++ VVD GAV +LV +
Sbjct: 120 AIVDCGALDTLVICLEDF-DPGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQE 178
Query: 585 STENVCEQAVWALGNIAGDSPYCRDIVLAAGVSPTLA 695
+ A AL +IA SP V+ AG LA
Sbjct: 179 PEIALKRIAASALSDIAKHSPELAQTVVDAGAVAHLA 215
Score = 35.1 bits (77), Expect = 0.25
Identities = 27/96 (28%), Positives = 45/96 (46%)
Frame = +3
Query: 405 AVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSG 584
AV+ +G VP + L+ AA AL++IA S + VVD GAV L ++
Sbjct: 162 AVVDAGAVPLLV-LCIQEPEIALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMILN 220
Query: 585 STENVCEQAVWALGNIAGDSPYCRDIVLAAGVSPTL 692
+ Q + AL ++ S ++V+ A + P +
Sbjct: 221 PDAKLKHQILSALSQVSKHSVDLAEMVVEAEIFPVV 256
>CR533552-1|CAG38583.1| 509|Homo sapiens SPAG6 protein.
Length = 509
Score = 41.9 bits (94), Expect = 0.002
Identities = 30/97 (30%), Positives = 46/97 (47%)
Frame = +3
Query: 402 DAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLS 581
+AV++ I+P+ + L +N + AA+ L + S + +VD GA++ LV L
Sbjct: 77 EAVVKCDILPQLVYSLAE-QNRFYKKAAAFVLRAVGKHSPQLAQAIVDCGALDTLVICLE 135
Query: 582 GSTENVCEQAVWALGNIAGDSPYCRDIVLAAGVSPTL 692
V E A WAL IA + V+ AG P L
Sbjct: 136 DFDPGVKEAAAWALRYIARHNAELSRAVVDAGAVPLL 172
Score = 41.1 bits (92), Expect = 0.004
Identities = 32/97 (32%), Positives = 48/97 (49%)
Frame = +3
Query: 405 AVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSG 584
A++ G + + L + +P ++ AAWAL IA ++ +R VVD GAV +LV +
Sbjct: 120 AIVDCGALDTLVICLEDF-DPGVKEAAAWALRYIARHNAELSRAVVDAGAVPLLVLCIQE 178
Query: 585 STENVCEQAVWALGNIAGDSPYCRDIVLAAGVSPTLA 695
+ A AL +IA SP V+ AG LA
Sbjct: 179 PEIALKRIAASALSDIAKHSPELAQTVVDAGAVAHLA 215
Score = 35.1 bits (77), Expect = 0.25
Identities = 27/96 (28%), Positives = 45/96 (46%)
Frame = +3
Query: 405 AVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSG 584
AV+ +G VP + L+ AA AL++IA S + VVD GAV L ++
Sbjct: 162 AVVDAGAVPLLV-LCIQEPEIALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMILN 220
Query: 585 STENVCEQAVWALGNIAGDSPYCRDIVLAAGVSPTL 692
+ Q + AL ++ S ++V+ A + P +
Sbjct: 221 PDAKLKHQILSALSQVSKHSVDLAEMVVEAEIFPVV 256
>AL513128-1|CAH72207.1| 246|Homo sapiens sperm associated antigen 6
protein.
Length = 246
Score = 41.5 bits (93), Expect = 0.003
Identities = 29/95 (30%), Positives = 45/95 (47%)
Frame = +3
Query: 402 DAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLS 581
+AV++ I+P+ + L +N + AA+ L + S + +VD GA++ LV L
Sbjct: 153 EAVVKCDILPQLVYSLAE-QNRFYKKAAAFVLRAVGKHSPQLAQAIVDCGALDTLVICLE 211
Query: 582 GSTENVCEQAVWALGNIAGDSPYCRDIVLAAGVSP 686
V E A WAL IA + V+ AG P
Sbjct: 212 DFDPGVKEAAAWALRYIARHNAELSQAVVDAGAVP 246
>AL158211-12|CAI15960.1| 246|Homo sapiens sperm associated antigen
6 protein.
Length = 246
Score = 41.5 bits (93), Expect = 0.003
Identities = 29/95 (30%), Positives = 45/95 (47%)
Frame = +3
Query: 402 DAVIQSGIVPKFIEFLTNHKNPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLS 581
+AV++ I+P+ + L +N + AA+ L + S + +VD GA++ LV L
Sbjct: 153 EAVVKCDILPQLVYSLAE-QNRFYKKAAAFVLRAVGKHSPQLAQAIVDCGALDTLVICLE 211
Query: 582 GSTENVCEQAVWALGNIAGDSPYCRDIVLAAGVSP 686
V E A WAL IA + V+ AG P
Sbjct: 212 DFDPGVKEAAAWALRYIARHNAELSQAVVDAGAVP 246
>BC041699-1|AAH41699.1| 659|Homo sapiens armadillo repeat
containing 8 protein.
Length = 659
Score = 40.7 bits (91), Expect = 0.005
Identities = 31/124 (25%), Positives = 58/124 (46%), Gaps = 1/124 (0%)
Frame = +3
Query: 309 VLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAA 488
++ V + P+E ++ L E +P + +++SG V + + LT +NP L+
Sbjct: 417 LMKVLQNAPDEILVVASSMLCNLLLEFSPSKEPILESGAV-ELLCGLTQSENPALRVNGI 475
Query: 489 WALTNIASGSSGQTRI-VVDYGAVNVLVGLLSGSTENVCEQAVWALGNIAGDSPYCRDIV 665
WAL N+A + + + ++ + L LLS S NV + + L N+ P+ I+
Sbjct: 476 WALMNMAFQAEQKIKADILRSLSTEQLFRLLSDSDLNVLMKTLGLLRNLLSTRPHIDKIM 535
Query: 666 LAAG 677
G
Sbjct: 536 STHG 539
>BC032661-1|AAH32661.1| 659|Homo sapiens armadillo repeat
containing 8 protein.
Length = 659
Score = 40.7 bits (91), Expect = 0.005
Identities = 31/124 (25%), Positives = 58/124 (46%), Gaps = 1/124 (0%)
Frame = +3
Query: 309 VLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAA 488
++ V + P+E ++ L E +P + +++SG V + + LT +NP L+
Sbjct: 417 LMKVLQNAPDEILVVASSMLCNLLLEFSPSKEPILESGAV-ELLCGLTQSENPALRVNGI 475
Query: 489 WALTNIASGSSGQTRI-VVDYGAVNVLVGLLSGSTENVCEQAVWALGNIAGDSPYCRDIV 665
WAL N+A + + + ++ + L LLS S NV + + L N+ P+ I+
Sbjct: 476 WALMNMAFQAEQKIKADILRSLSTEQLFRLLSDSDLNVLMKTLGLLRNLLSTRPHIDKIM 535
Query: 666 LAAG 677
G
Sbjct: 536 STHG 539
>AL096748-1|CAB46423.1| 242|Homo sapiens hypothetical protein
protein.
Length = 242
Score = 40.3 bits (90), Expect = 0.007
Identities = 31/123 (25%), Positives = 57/123 (46%), Gaps = 1/123 (0%)
Frame = +3
Query: 312 LAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAAW 491
+ V + P+E ++ L E +P + +++SG V + + LT +NP L+ W
Sbjct: 1 MKVLQNAPDEILVVASSMLCNLLLEFSPSKEPILESGAV-ELLCGLTQSENPALRVNGIW 59
Query: 492 ALTNIASGSSGQTRI-VVDYGAVNVLVGLLSGSTENVCEQAVWALGNIAGDSPYCRDIVL 668
AL N+A + + + ++ + L LLS S NV + + L N+ P+ I+
Sbjct: 60 ALMNMAFQAEQKIKADILRSLSTEQLFRLLSDSDLNVLMKTLGLLRNLLSTRPHIDKIMS 119
Query: 669 AAG 677
G
Sbjct: 120 THG 122
>AK001882-1|BAA91959.1| 431|Homo sapiens protein ( Homo sapiens
cDNA FLJ11020 fis, clone PLACE1003625, weakly similar to
ARMADILLO SEGMENT POLARITY PROTEIN. ).
Length = 431
Score = 38.7 bits (86), Expect = 0.020
Identities = 30/124 (24%), Positives = 58/124 (46%), Gaps = 1/124 (0%)
Frame = +3
Query: 309 VLAVYLDNPEEQVIATQKFRKLLSKEPNPPIDAVIQSGIVPKFIEFLTNHKNPTLQFEAA 488
++ V + P+E ++ L E +P + +++SG V + + LT +NP L+
Sbjct: 189 LMKVLQNAPDEILVVASSMLCNLLLEFSPSKEPILESGAV-ELLCGLTQSENPALRVNGI 247
Query: 489 WALTNIASGSSGQTRI-VVDYGAVNVLVGLLSGSTENVCEQAVWALGNIAGDSPYCRDIV 665
WAL N+A + + + ++ + L LLS S NV + + L ++ P+ I+
Sbjct: 248 WALMNMAFQAEQKIKADILRSLSTEQLFRLLSDSDLNVLMKTLGLLRSLLSTRPHIDKIM 307
Query: 666 LAAG 677
G
Sbjct: 308 STHG 311
>AK223275-1|BAD96995.1| 1181|Homo sapiens AT rich interactive domain
1A (SWI- like) isoform a variant protein.
Length = 1181
Score = 35.9 bits (79), Expect = 0.14
Identities = 20/51 (39%), Positives = 28/51 (54%), Gaps = 1/51 (1%)
Frame = +3
Query: 438 IEFLTNHKNPTLQFEAAWALTNIASGSSGQTR-IVVDYGAVNVLVGLLSGS 587
+ FL++ KNP + A L N+A G S TR I V G++ L+G L S
Sbjct: 1048 VRFLSDRKNPVCREMAVVLLANLAQGDSLATRAIAVQKGSIGNLLGFLEDS 1098
>X63465-1|CAA45067.1| 558|Homo sapiens smg GDS protein.
Length = 558
Score = 34.7 bits (76), Expect = 0.33
Identities = 21/51 (41%), Positives = 28/51 (54%)
Frame = +3
Query: 540 VDYGAVNVLVGLLSGSTENVCEQAVWALGNIAGDSPYCRDIVLAAGVSPTL 692
VD G ++ LV LL+ + V Q ALGNI DS + ++ GV PTL
Sbjct: 86 VDAGLISPLVQLLNSKDQEVLLQTGRALGNICYDSHSLQAQLINMGVIPTL 136
>BC099845-1|AAH99845.1| 559|Homo sapiens RAP1GDS1 protein protein.
Length = 559
Score = 34.7 bits (76), Expect = 0.33
Identities = 21/51 (41%), Positives = 28/51 (54%)
Frame = +3
Query: 540 VDYGAVNVLVGLLSGSTENVCEQAVWALGNIAGDSPYCRDIVLAAGVSPTL 692
VD G ++ LV LL+ + V Q ALGNI DS + ++ GV PTL
Sbjct: 87 VDAGLISPLVQLLNSKDQEVLLQTGRALGNICYDSHSLQAQLINMGVIPTL 137
>BC099708-1|AAH99708.1| 558|Homo sapiens RAP1GDS1 protein protein.
Length = 558
Score = 34.7 bits (76), Expect = 0.33
Identities = 21/51 (41%), Positives = 28/51 (54%)
Frame = +3
Query: 540 VDYGAVNVLVGLLSGSTENVCEQAVWALGNIAGDSPYCRDIVLAAGVSPTL 692
VD G ++ LV LL+ + V Q ALGNI DS + ++ GV PTL
Sbjct: 86 VDAGLISPLVQLLNSKDQEVLLQTGRALGNICYDSHSLQAQLINMGVIPTL 136
>BC098334-1|AAH98334.1| 558|Homo sapiens RAP1GDS1 protein protein.
Length = 558
Score = 34.7 bits (76), Expect = 0.33
Identities = 21/51 (41%), Positives = 28/51 (54%)
Frame = +3
Query: 540 VDYGAVNVLVGLLSGSTENVCEQAVWALGNIAGDSPYCRDIVLAAGVSPTL 692
VD G ++ LV LL+ + V Q ALGNI DS + ++ GV PTL
Sbjct: 86 VDAGLISPLVQLLNSKDQEVLLQTGRALGNICYDSHSLQAQLINMGVIPTL 136
>BC112895-1|AAI12896.1| 164|Homo sapiens ARID1A protein protein.
Length = 164
Score = 33.9 bits (74), Expect = 0.57
Identities = 19/51 (37%), Positives = 27/51 (52%), Gaps = 1/51 (1%)
Frame = +3
Query: 438 IEFLTNHKNPTLQFEAAWALTNIASGSSGQTR-IVVDYGAVNVLVGLLSGS 587
+ FL++ KNP + A L N+A G S R I V G++ L+G L S
Sbjct: 31 VRFLSDRKNPVCREMAVVLLANLAQGDSLAARAIAVQKGSIGNLLGFLEDS 81
>AL512408-3|CAI23484.1| 2285|Homo sapiens AT rich interactive domain
1A (SWI-like) protein.
Length = 2285
Score = 33.9 bits (74), Expect = 0.57
Identities = 19/51 (37%), Positives = 27/51 (52%), Gaps = 1/51 (1%)
Frame = +3
Query: 438 IEFLTNHKNPTLQFEAAWALTNIASGSSGQTR-IVVDYGAVNVLVGLLSGS 587
+ FL++ KNP + A L N+A G S R I V G++ L+G L S
Sbjct: 2152 VRFLSDRKNPVCREMAVVLLANLAQGDSLAARAIAVQKGSIGNLLGFLEDS 2202
>AL512408-1|CAI23482.1| 1685|Homo sapiens AT rich interactive domain
1A (SWI-like) protein.
Length = 1685
Score = 33.9 bits (74), Expect = 0.57
Identities = 19/51 (37%), Positives = 27/51 (52%), Gaps = 1/51 (1%)
Frame = +3
Query: 438 IEFLTNHKNPTLQFEAAWALTNIASGSSGQTR-IVVDYGAVNVLVGLLSGS 587
+ FL++ KNP + A L N+A G S R I V G++ L+G L S
Sbjct: 1552 VRFLSDRKNPVCREMAVVLLANLAQGDSLAARAIAVQKGSIGNLLGFLEDS 1602
>AL034380-9|CAI21623.1| 2285|Homo sapiens AT rich interactive domain
1A (SWI-like) protein.
Length = 2285
Score = 33.9 bits (74), Expect = 0.57
Identities = 19/51 (37%), Positives = 27/51 (52%), Gaps = 1/51 (1%)
Frame = +3
Query: 438 IEFLTNHKNPTLQFEAAWALTNIASGSSGQTR-IVVDYGAVNVLVGLLSGS 587
+ FL++ KNP + A L N+A G S R I V G++ L+G L S
Sbjct: 2152 VRFLSDRKNPVCREMAVVLLANLAQGDSLAARAIAVQKGSIGNLLGFLEDS 2202
>AL034380-6|CAI21621.1| 1685|Homo sapiens AT rich interactive domain
1A (SWI-like) protein.
Length = 1685
Score = 33.9 bits (74), Expect = 0.57
Identities = 19/51 (37%), Positives = 27/51 (52%), Gaps = 1/51 (1%)
Frame = +3
Query: 438 IEFLTNHKNPTLQFEAAWALTNIASGSSGQTR-IVVDYGAVNVLVGLLSGS 587
+ FL++ KNP + A L N+A G S R I V G++ L+G L S
Sbjct: 1552 VRFLSDRKNPVCREMAVVLLANLAQGDSLAARAIAVQKGSIGNLLGFLEDS 1602
>AK074940-1|BAC11306.1| 754|Homo sapiens protein ( Homo sapiens
cDNA FLJ90459 fis, clone NT2RP3001754. ).
Length = 754
Score = 33.9 bits (74), Expect = 0.57
Identities = 19/51 (37%), Positives = 27/51 (52%), Gaps = 1/51 (1%)
Frame = +3
Query: 438 IEFLTNHKNPTLQFEAAWALTNIASGSSGQTR-IVVDYGAVNVLVGLLSGS 587
+ FL++ KNP + A L N+A G S R I V G++ L+G L S
Sbjct: 621 VRFLSDRKNPVCREMAVVLLANLAQGDSLAARAIAVQKGSIGNLLGFLEDS 671
>AK027655-1|BAB55270.1| 613|Homo sapiens protein ( Homo sapiens
cDNA FLJ14749 fis, clone NT2RP3002876, weakly similar to
Drosophila melanogaster eyelid (eld) mRNA. ).
Length = 613
Score = 33.9 bits (74), Expect = 0.57
Identities = 19/51 (37%), Positives = 27/51 (52%), Gaps = 1/51 (1%)
Frame = +3
Query: 438 IEFLTNHKNPTLQFEAAWALTNIASGSSGQTR-IVVDYGAVNVLVGLLSGS 587
+ FL++ KNP + A L N+A G S R I V G++ L+G L S
Sbjct: 480 VRFLSDRKNPVCREMAVVLLANLAQGDSLAARAIAVQKGSIGNLLGFLEDS 530
>AK027467-1|BAB55132.1| 375|Homo sapiens protein ( Homo sapiens
cDNA FLJ14561 fis, clone NT2RM2002091, weakly similar to
Drosophila melanogaster eyelid (eld) mRNA. ).
Length = 375
Score = 33.9 bits (74), Expect = 0.57
Identities = 19/51 (37%), Positives = 27/51 (52%), Gaps = 1/51 (1%)
Frame = +3
Query: 438 IEFLTNHKNPTLQFEAAWALTNIASGSSGQTR-IVVDYGAVNVLVGLLSGS 587
+ FL++ KNP + A L N+A G S R I V G++ L+G L S
Sbjct: 242 VRFLSDRKNPVCREMAVVLLANLAQGDSLAARAIAVQKGSIGNLLGFLEDS 292
>AK027442-1|BAB55114.1| 527|Homo sapiens protein ( Homo sapiens
cDNA FLJ14536 fis, clone NT2RM2001105, weakly similar to
Drosophila melanogaster eyelid (eld) mRNA. ).
Length = 527
Score = 33.9 bits (74), Expect = 0.57
Identities = 19/51 (37%), Positives = 27/51 (52%), Gaps = 1/51 (1%)
Frame = +3
Query: 438 IEFLTNHKNPTLQFEAAWALTNIASGSSGQTR-IVVDYGAVNVLVGLLSGS 587
+ FL++ KNP + A L N+A G S R I V G++ L+G L S
Sbjct: 394 VRFLSDRKNPVCREMAVVLLANLAQGDSLAARAIAVQKGSIGNLLGFLEDS 444
>AF521670-1|AAN03446.1| 1999|Homo sapiens SWI/SNF chromatin remodeling
complex subunit OSA1 protein.
Length = 1999
Score = 33.9 bits (74), Expect = 0.57
Identities = 19/51 (37%), Positives = 27/51 (52%), Gaps = 1/51 (1%)
Frame = +3
Query: 438 IEFLTNHKNPTLQFEAAWALTNIASGSSGQTR-IVVDYGAVNVLVGLLSGS 587
+ FL++ KNP + A L N+A G S R I V G++ L+G L S
Sbjct: 1866 VRFLSDRKNPVCREMAVVLLANLAQGDSLAARAIAVQKGSIGNLLGFLEDS 1916
>AF265208-1|AAF75765.1| 1927|Homo sapiens SWI-SNF complex protein p270
protein.
Length = 1927
Score = 33.9 bits (74), Expect = 0.57
Identities = 19/51 (37%), Positives = 27/51 (52%), Gaps = 1/51 (1%)
Frame = +3
Query: 438 IEFLTNHKNPTLQFEAAWALTNIASGSSGQTR-IVVDYGAVNVLVGLLSGS 587
+ FL++ KNP + A L N+A G S R I V G++ L+G L S
Sbjct: 1794 VRFLSDRKNPVCREMAVVLLANLAQGDSLAARAIAVQKGSIGNLLGFLEDS 1844
>AF231056-1|AAG33967.1| 2285|Homo sapiens BRG1-Associated Factor 250a
protein.
Length = 2285
Score = 33.9 bits (74), Expect = 0.57
Identities = 19/51 (37%), Positives = 27/51 (52%), Gaps = 1/51 (1%)
Frame = +3
Query: 438 IEFLTNHKNPTLQFEAAWALTNIASGSSGQTR-IVVDYGAVNVLVGLLSGS 587
+ FL++ KNP + A L N+A G S R I V G++ L+G L S
Sbjct: 2152 VRFLSDRKNPVCREMAVVLLANLAQGDSLAARAIAVQKGSIGNLLGFLEDS 2202
>AF219114-1|AAG17549.2| 1939|Homo sapiens chromatin remodelling factor
p250 protein.
Length = 1939
Score = 33.9 bits (74), Expect = 0.57
Identities = 19/51 (37%), Positives = 27/51 (52%), Gaps = 1/51 (1%)
Frame = +3
Query: 438 IEFLTNHKNPTLQFEAAWALTNIASGSSGQTR-IVVDYGAVNVLVGLLSGS 587
+ FL++ KNP + A L N+A G S R I V G++ L+G L S
Sbjct: 1806 VRFLSDRKNPVCREMAVVLLANLAQGDSLAARAIAVQKGSIGNLLGFLEDS 1856
>AF268913-1|AAK54505.1| 1685|Homo sapiens OSA1 nuclear protein
protein.
Length = 1685
Score = 32.3 bits (70), Expect = 1.7
Identities = 18/51 (35%), Positives = 27/51 (52%), Gaps = 1/51 (1%)
Frame = +3
Query: 438 IEFLTNHKNPTLQFEAAWALTNIASGSSGQTR-IVVDYGAVNVLVGLLSGS 587
+ FL++ +NP + A L N+A G S R I V G++ L+G L S
Sbjct: 1552 VRFLSDRENPVCREMAVVLLANLAQGDSLAARAIAVQKGSIGNLLGFLEDS 1602
>L09190-1|AAA65582.1| 1898|Homo sapiens trichohyalin protein.
Length = 1898
Score = 31.1 bits (67), Expect = 4.0
Identities = 14/30 (46%), Positives = 21/30 (70%)
Frame = +3
Query: 129 LSADELRRRREEEGVQLRKQKREQQLFKRR 218
L ELRR R+EE Q ++ +REQQL +++
Sbjct: 281 LERQELRRERQEEEQQQQRLRREQQLRRKQ 310
>AL589986-1|CAH70024.1| 1943|Homo sapiens trichohyalin protein.
Length = 1943
Score = 31.1 bits (67), Expect = 4.0
Identities = 14/30 (46%), Positives = 21/30 (70%)
Frame = +3
Query: 129 LSADELRRRREEEGVQLRKQKREQQLFKRR 218
L ELRR R+EE Q ++ +REQQL +++
Sbjct: 281 LERQELRRERQEEEQQQQRLRREQQLRRKQ 310
>AM156947-1|CAJ42307.1| 1221|Homo sapiens centrosome and spindle
pole associated protein 1 protein.
Length = 1221
Score = 30.7 bits (66), Expect = 5.3
Identities = 32/98 (32%), Positives = 46/98 (46%), Gaps = 3/98 (3%)
Frame = +3
Query: 126 GLSADELRRRREEEGVQLRKQKREQQLFKRRNVNLPGTNAAGAASQEDINISPSDCITPD 305
G + ++RR+E+ ++L +Q EQQ KRR +L AA A +D SP D +
Sbjct: 375 GEDRELIQRRKEKYRLELLEQMAEQQRNKRREKDLELRVAASGA--QDPEKSP-DRLKQF 431
Query: 306 MVLAVYLDN---PEEQVIATQKFRKLLSKEPNPPIDAV 410
V + + PE IA Q LS PPI +V
Sbjct: 432 SVAPRHFEEMIPPERPRIAFQTPLPPLSAPSVPPIPSV 469
>AJ583433-1|CAE47426.1| 876|Homo sapiens centrosome spindle pole
associated protein protein.
Length = 876
Score = 30.7 bits (66), Expect = 5.3
Identities = 32/98 (32%), Positives = 46/98 (46%), Gaps = 3/98 (3%)
Frame = +3
Query: 126 GLSADELRRRREEEGVQLRKQKREQQLFKRRNVNLPGTNAAGAASQEDINISPSDCITPD 305
G + ++RR+E+ ++L +Q EQQ KRR +L AA A +D SP D +
Sbjct: 81 GEDRELIQRRKEKYRLELLEQMAEQQRNKRREKDLELRVAASGA--QDPEKSP-DRLKQF 137
Query: 306 MVLAVYLDN---PEEQVIATQKFRKLLSKEPNPPIDAV 410
V + + PE IA Q LS PPI +V
Sbjct: 138 SVAPRHFEEMIPPERPRIAFQTPLPPLSAPSVPPIPSV 175
>BC039312-1|AAH39312.1| 872|Homo sapiens armadillo repeat
containing 3 protein.
Length = 872
Score = 30.3 bits (65), Expect = 7.0
Identities = 20/60 (33%), Positives = 30/60 (50%)
Frame = +3
Query: 462 NPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWALGNIAGD 641
N +Q +AA A+T A +T + + G + LV LL + V + A WA+ AGD
Sbjct: 452 NTVVQSKAALAVTATACDVEARTELR-NSGGLEPLVELLRSKNDEVRKHASWAVMVCAGD 510
>AY436643-1|AAR99738.1| 688|Homo sapiens beta-catenin-like protein
protein.
Length = 688
Score = 30.3 bits (65), Expect = 7.0
Identities = 20/60 (33%), Positives = 30/60 (50%)
Frame = +3
Query: 462 NPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWALGNIAGD 641
N +Q +AA A+T A +T + + G + LV LL + V + A WA+ AGD
Sbjct: 452 NTVVQSKAALAVTATACDVEARTELR-NSGGLEPLVELLRSKNDEVRKHASWAVMVCAGD 510
>AL139815-2|CAH72189.1| 875|Homo sapiens novel protein protein.
Length = 875
Score = 30.3 bits (65), Expect = 7.0
Identities = 20/60 (33%), Positives = 30/60 (50%)
Frame = +3
Query: 462 NPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWALGNIAGD 641
N +Q +AA A+T A +T + + G + LV LL + V + A WA+ AGD
Sbjct: 452 NTVVQSKAALAVTATACDVEARTELR-NSGGLEPLVELLRSKNDEVRKHASWAVMVCAGD 510
>AL139815-1|CAH72188.1| 546|Homo sapiens novel protein protein.
Length = 546
Score = 30.3 bits (65), Expect = 7.0
Identities = 20/60 (33%), Positives = 30/60 (50%)
Frame = +3
Query: 462 NPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWALGNIAGD 641
N +Q +AA A+T A +T + + G + LV LL + V + A WA+ AGD
Sbjct: 388 NTVVQSKAALAVTATACDVEARTELR-NSGGLEPLVELLRSKNDEVRKHASWAVMVCAGD 446
>AK057389-1|BAB71463.1| 669|Homo sapiens protein ( Homo sapiens
cDNA FLJ32827 fis, clone TESTI2003109, weakly similar to
VACUOLAR PROTEIN 8. ).
Length = 669
Score = 30.3 bits (65), Expect = 7.0
Identities = 20/60 (33%), Positives = 30/60 (50%)
Frame = +3
Query: 462 NPTLQFEAAWALTNIASGSSGQTRIVVDYGAVNVLVGLLSGSTENVCEQAVWALGNIAGD 641
N +Q +AA A+T A +T + + G + LV LL + V + A WA+ AGD
Sbjct: 452 NTVVQSKAALAVTATACDVEARTELR-NSGGLEPLVELLRSKNDEVRKHASWAVMVCAGD 510
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 93,214,607
Number of Sequences: 237096
Number of extensions: 1866915
Number of successful extensions: 6296
Number of sequences better than 10.0: 79
Number of HSP's better than 10.0 without gapping: 5429
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6111
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8175213644
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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