Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= bmnc22p14
(736 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q2F5Q8 Cluster: Homocysteine S-methyltransferase; n=4; ... 423 e-117
UniRef50_UPI00015B4DEA Cluster: PREDICTED: similar to homocystei... 257 2e-67
UniRef50_UPI0000519B36 Cluster: PREDICTED: similar to CG10621-PA... 237 2e-61
UniRef50_Q9VJ31 Cluster: CG10623-PA; n=11; Diptera|Rep: CG10623-... 225 1e-57
UniRef50_Q5PNQ3 Cluster: Novel protein containing a homocysteine... 215 1e-54
UniRef50_Q4S116 Cluster: Chromosome 1 SCAF14770, whole genome sh... 199 5e-50
UniRef50_A7S7I8 Cluster: Predicted protein; n=2; Nematostella ve... 189 7e-47
UniRef50_Q8LAX0 Cluster: Homocysteine S-methyltransferase 3; n=3... 168 1e-40
UniRef50_Q0TXM4 Cluster: Putative uncharacterized protein; n=1; ... 164 2e-39
UniRef50_O31463 Cluster: YbgG protein; n=6; Firmicutes|Rep: YbgG... 161 2e-38
UniRef50_Q47690 Cluster: Homocysteine S-methyltransferase; n=20;... 150 4e-35
UniRef50_Q3CZT7 Cluster: Homocysteine S-methyltransferase; n=15;... 147 3e-34
UniRef50_Q4Q0C9 Cluster: Homocysteine S-methyltransferase, putat... 142 1e-32
UniRef50_A3TGH3 Cluster: Homocysteine methyltransferase; n=1; Ja... 130 5e-29
UniRef50_Q88XC1 Cluster: Homocysteine S-methyltransferase; n=2; ... 128 2e-28
UniRef50_Q7D740 Cluster: Homocysteine S-methyltransferase; n=14;... 128 2e-28
UniRef50_Q1GBT8 Cluster: Homocysteine S-methyltransferase; n=2; ... 124 3e-27
UniRef50_A5CB34 Cluster: Putative uncharacterized protein; n=1; ... 118 2e-25
UniRef50_Q0BQM8 Cluster: Homocysteine S-methyltransferase; n=1; ... 116 6e-25
UniRef50_A6G853 Cluster: Homocysteine methyltransferase; n=1; Pl... 115 1e-24
UniRef50_UPI000050FD2A Cluster: COG2040: Homocysteine/selenocyst... 114 2e-24
UniRef50_A5VKC8 Cluster: Homocysteine S-methyltransferase; n=2; ... 114 2e-24
UniRef50_Q49V93 Cluster: Putative homocysteine S-methyltransfera... 112 1e-23
UniRef50_Q5FKC1 Cluster: Homocysteine S-methyltransferase; n=2; ... 110 4e-23
UniRef50_A5DTG6 Cluster: Putative uncharacterized protein; n=1; ... 107 3e-22
UniRef50_Q59QD2 Cluster: Putative uncharacterized protein SAM4; ... 102 8e-21
UniRef50_Q6BZK6 Cluster: Debaryomyces hansenii chromosome A of s... 100 3e-20
UniRef50_A3LQC9 Cluster: AdoMet-homocysteine methyltransferase; ... 94 4e-18
UniRef50_A5DCB0 Cluster: Putative uncharacterized protein; n=1; ... 93 6e-18
UniRef50_Q2TXK9 Cluster: Predicted protein; n=2; Trichocomaceae|... 83 9e-15
UniRef50_Q7SFT2 Cluster: Putative uncharacterized protein NCU007... 81 3e-14
UniRef50_Q6C0D6 Cluster: Yarrowia lipolytica chromosome F of str... 81 3e-14
UniRef50_Q4PDM6 Cluster: Putative uncharacterized protein; n=1; ... 81 3e-14
UniRef50_A6S563 Cluster: Putative uncharacterized protein; n=2; ... 80 5e-14
UniRef50_UPI0000E4900F Cluster: PREDICTED: similar to 5-methylte... 79 1e-13
UniRef50_Q1DSS3 Cluster: Putative uncharacterized protein; n=1; ... 75 2e-12
UniRef50_A2R696 Cluster: Contig An15c0240, complete genome; n=6;... 73 7e-12
UniRef50_Q5KA93 Cluster: Homocysteine S-methyltransferase, putat... 72 2e-11
UniRef50_A4R5G4 Cluster: Putative uncharacterized protein; n=1; ... 70 5e-11
UniRef50_A7TSR2 Cluster: Putative uncharacterized protein; n=1; ... 69 2e-10
UniRef50_Q753B4 Cluster: AFR410Wp; n=1; Eremothecium gossypii|Re... 68 3e-10
UniRef50_A4B5J7 Cluster: Homocysteine S-methyltransferase family... 66 1e-09
UniRef50_UPI0001555A4D Cluster: PREDICTED: similar to RB-associa... 64 3e-09
UniRef50_Q966F6 Cluster: Putative uncharacterized protein T13G4.... 63 8e-09
UniRef50_P74718 Cluster: Slr1189 protein; n=1; Synechocystis sp.... 62 2e-08
UniRef50_Q98KX0 Cluster: Mlr1281 protein; n=4; Proteobacteria|Re... 60 6e-08
UniRef50_P87138 Cluster: Uncharacterized protein C57A7.07c; n=1;... 59 1e-07
UniRef50_Q0LM71 Cluster: Methylenetetrahydrofolate reductase; n=... 57 4e-07
UniRef50_Q8R927 Cluster: Methionine synthase I, cobalamin-bindin... 55 2e-06
UniRef50_Q1IQK2 Cluster: 5-methyltetrahydrofolate--homocysteine ... 55 2e-06
UniRef50_Q08985 Cluster: Homocysteine S-methyltransferase 2; n=9... 55 2e-06
UniRef50_A4XIN4 Cluster: Homocysteine S-methyltransferase; n=1; ... 54 4e-06
UniRef50_A1SWN6 Cluster: Homocysteine S-methyltransferase; n=2; ... 54 4e-06
UniRef50_A5UPF4 Cluster: Methionine synthase; n=4; Chloroflexace... 54 5e-06
UniRef50_Q024B4 Cluster: Homocysteine S-methyltransferase; n=1; ... 53 6e-06
UniRef50_A5TSW8 Cluster: Methionine synthase; n=3; Fusobacterium... 53 6e-06
UniRef50_Q15S12 Cluster: Homocysteine S-methyltransferase; n=1; ... 53 8e-06
UniRef50_Q01YW7 Cluster: Methionine synthase; n=2; Bacteria|Rep:... 53 8e-06
UniRef50_Q7VBY3 Cluster: 5-methyltetrahydrofolate--homocysteine ... 52 1e-05
UniRef50_Q93A68 Cluster: Methylenetetrahydrofolate reductase; n=... 52 1e-05
UniRef50_Q2LWJ5 Cluster: 5-methyltetrahydrofolate--homocysteine ... 52 2e-05
UniRef50_Q99707 Cluster: Methionine synthase; n=268; cellular or... 52 2e-05
UniRef50_Q2S678 Cluster: Vitamin B12-dependent methionine syntha... 51 3e-05
UniRef50_UPI0000E47473 Cluster: PREDICTED: hypothetical protein;... 50 4e-05
UniRef50_Q4DI99 Cluster: Homocysteine S-methyltransferase, putat... 50 4e-05
UniRef50_Q30ZI4 Cluster: Vitamin B12-dependent methionine syntha... 50 8e-05
UniRef50_Q2AGF5 Cluster: Dihydropteroate synthase, DHPS:Homocyst... 49 1e-04
UniRef50_A7SKT1 Cluster: Predicted protein; n=4; Eumetazoa|Rep: ... 49 1e-04
UniRef50_A4XIN5 Cluster: Methylenetetrahydrofolate reductase; n=... 49 1e-04
UniRef50_A7RIN6 Cluster: Predicted protein; n=2; Nematostella ve... 49 1e-04
UniRef50_Q4FMM0 Cluster: Homocysteine S-methyltransferase; n=3; ... 48 2e-04
UniRef50_A7AL74 Cluster: Putative uncharacterized protein; n=1; ... 48 2e-04
UniRef50_A6G2A6 Cluster: Homocysteine S-methyltransferase, putat... 48 2e-04
UniRef50_A5KL27 Cluster: Putative uncharacterized protein; n=4; ... 48 2e-04
UniRef50_Q4GZ92 Cluster: Homocysteine S-methyltransferase, putat... 48 2e-04
UniRef50_A5WFJ9 Cluster: Homocysteine S-methyltransferase; n=32;... 48 2e-04
UniRef50_Q748T0 Cluster: 5-methyltetrahydrofolate-homocysteine m... 48 3e-04
UniRef50_A4J6L9 Cluster: Homocysteine S-methyltransferase; n=1; ... 48 3e-04
UniRef50_A7CWS4 Cluster: Homocysteine S-methyltransferase precur... 47 4e-04
UniRef50_A3JFK5 Cluster: Putative uncharacterized protein; n=1; ... 47 4e-04
UniRef50_A0Z513 Cluster: Putative uncharacterized protein; n=1; ... 47 6e-04
UniRef50_A0LDY2 Cluster: Methionine synthase; n=54; Bacteria|Rep... 47 6e-04
UniRef50_Q9WYA5 Cluster: 5-methyltetrahydrofolate S-homocysteine... 46 7e-04
UniRef50_Q93088 Cluster: Betaine--homocysteine S-methyltransfera... 46 7e-04
UniRef50_Q55786 Cluster: Methionine synthase; n=5; Cyanobacteria... 46 0.001
UniRef50_A7H6G1 Cluster: Methionine synthase; n=3; Bacteria|Rep:... 46 0.001
UniRef50_A6DGP4 Cluster: 5-methyltetrahydrofolate--homocysteine ... 46 0.001
UniRef50_A3UPV1 Cluster: Homocysteine S-methyltransferase family... 46 0.001
UniRef50_A3S2V2 Cluster: 5-methyltetrahydrofolate--homocysteine ... 46 0.001
UniRef50_Q6AL45 Cluster: Related to 5-methyltetrahydrofolate--ho... 45 0.002
UniRef50_A3ERA3 Cluster: Methionine synthase I, cobalamin-bindin... 45 0.002
UniRef50_Q9I2Q2 Cluster: Methionine synthase; n=95; Bacteria|Rep... 45 0.002
UniRef50_Q88X64 Cluster: Methylenetetrahydrofolate reductase; n=... 45 0.002
UniRef50_Q2JJL4 Cluster: Methionine synthase; n=25; Cyanobacteri... 45 0.002
UniRef50_Q1GGL5 Cluster: Homocysteine S-methyltransferase; n=30;... 45 0.002
UniRef50_Q8DCJ7 Cluster: Methionine synthase; n=51; Bacteria|Rep... 45 0.002
UniRef50_A7N4Y4 Cluster: Putative uncharacterized protein; n=1; ... 44 0.004
UniRef50_A0VUF3 Cluster: Homocysteine S-methyltransferase; n=5; ... 44 0.004
UniRef50_Q5LN14 Cluster: Homocysteine S-methyltransferase family... 43 0.007
UniRef50_Q1IL23 Cluster: Methylenetetrahydrofolate reductase; n=... 43 0.007
UniRef50_Q4Y025 Cluster: Putative uncharacterized protein; n=4; ... 43 0.007
UniRef50_Q7M929 Cluster: S-METHYLTRANSFERASE; n=1; Wolinella suc... 43 0.009
UniRef50_A6PRW5 Cluster: Methylenetetrahydrofolate reductase; n=... 43 0.009
UniRef50_A7DNT5 Cluster: Homocysteine S-methyltransferase; n=1; ... 43 0.009
UniRef50_A6TTI3 Cluster: Homocysteine S-methyltransferase; n=2; ... 42 0.016
UniRef50_Q9KCE1 Cluster: 5-methyltetrahydrofolate S-homocysteine... 42 0.021
UniRef50_Q67LG1 Cluster: 5-methyltetrahydrofolate S-homocysteine... 41 0.027
UniRef50_Q2LQ11 Cluster: Methylenetetrahydrofolate reductase; n=... 40 0.048
UniRef50_Q9KCE2 Cluster: Methylenetetrahydrofolate reductase; n=... 40 0.084
UniRef50_Q5FP86 Cluster: 5-Methyltetrahydrofolate-S-homocysteine... 40 0.084
UniRef50_Q18RA6 Cluster: Homocysteine S-methyltransferase; n=2; ... 40 0.084
UniRef50_A7C1C8 Cluster: 5-methyltetrahydrofolate--homocysteine ... 40 0.084
UniRef50_Q5UEY6 Cluster: Putative homocysteine S-methyltransfera... 39 0.11
UniRef50_A6Q2F4 Cluster: 5-methyltetrahydrofolate--homocysteine ... 39 0.11
UniRef50_Q4V9Q6 Cluster: Apolipoprotein A-IV; n=11; Clupeocephal... 39 0.15
UniRef50_Q22HI1 Cluster: Homocysteine S-methyltransferase family... 38 0.26
UniRef50_A0RW49 Cluster: Methionine synthase I (Cobalamin-depend... 38 0.26
UniRef50_Q9WYU7 Cluster: Putative uncharacterized protein; n=2; ... 38 0.34
UniRef50_Q20HV9 Cluster: Msh; n=2; Agrobacterium tumefaciens|Rep... 37 0.45
UniRef50_A4EBI1 Cluster: Putative uncharacterized protein; n=1; ... 37 0.45
UniRef50_Q194H8 Cluster: TRNA-i(6)A37 thiotransferase enzyme Mia... 37 0.59
UniRef50_Q8ESE8 Cluster: Betaine-homocysteine methyltransferase;... 36 0.78
UniRef50_A5DLU3 Cluster: Putative uncharacterized protein; n=1; ... 36 1.0
UniRef50_A4EKV4 Cluster: Methionine synthase I; n=5; Proteobacte... 35 1.8
UniRef50_A1SNY1 Cluster: Metallophosphoesterase; n=1; Nocardioid... 35 1.8
UniRef50_A5K8K1 Cluster: Putative uncharacterized protein; n=1; ... 35 1.8
UniRef50_A5FRS2 Cluster: SMC domain protein; n=3; Dehalococcoide... 35 2.4
UniRef50_O34073 Cluster: ORF42; n=2; unclassified Siphoviridae|R... 35 2.4
UniRef50_P47723 Cluster: Phosphomannomutase; n=1; Mycoplasma pir... 35 2.4
UniRef50_A5TSJ3 Cluster: Putative uncharacterized protein; n=1; ... 34 3.1
UniRef50_Q4HKG9 Cluster: Flagellar hook-associated protein 2 (Fl... 33 5.5
UniRef50_A6CG77 Cluster: Polyhydroxyalkanoate synthesis represso... 33 5.5
UniRef50_A4J1H2 Cluster: Putative uncharacterized protein; n=2; ... 33 5.5
UniRef50_A3JU33 Cluster: Homocysteine S-methyltransferase; n=1; ... 33 5.5
UniRef50_Q8JKN6 Cluster: Orf76; n=1; Heliothis zea virus 1|Rep: ... 33 7.3
UniRef50_Q93HC9 Cluster: Putative hydrolase; n=1; Streptomyces a... 33 9.6
UniRef50_A1DNS1 Cluster: C2H2 type zinc finger domain protein; n... 33 9.6
>UniRef50_Q2F5Q8 Cluster: Homocysteine S-methyltransferase; n=4;
Endopterygota|Rep: Homocysteine S-methyltransferase -
Bombyx mori (Silk moth)
Length = 325
Score = 423 bits (1042), Expect = e-117
Identities = 200/202 (99%), Positives = 200/202 (99%)
Frame = +3
Query: 129 MSNFEVSSKTVFVLDGGFSTQLTCHAGHTADGDPLWSARFLKTHPQDVINTHLDFLRAGS 308
MSNFEVSSKTVFVLDGGFSTQLTCHAGHTADGDPL SARFLKTHPQDVINTHLDFLRAGS
Sbjct: 1 MSNFEVSSKTVFVLDGGFSTQLTCHAGHTADGDPLGSARFLKTHPQDVINTHLDFLRAGS 60
Query: 309 DIIETNTYQASVDGFVKHLNLTVEESYELIKSAVEFARTARDLYLQECQESNLSGRKPLI 488
DIIETNTYQASVDG VKHLNLTVEESYELIKSAVEFARTARDLYLQECQESNLSGRKPLI
Sbjct: 61 DIIETNTYQASVDGLVKHLNLTVEESYELIKSAVEFARTARDLYLQECQESNLSGRKPLI 120
Query: 489 AGSVGPYGAYLHDTSEYTGNYADNTTKETIKNWHRTRIQALVEAGVDILAFETIPCQKEA 668
AGSVGPYGAYLHDTSEYTGNYADNTTKETIKNWHRTRIQALVEAGVDILAFETIPCQKEA
Sbjct: 121 AGSVGPYGAYLHDTSEYTGNYADNTTKETIKNWHRTRIQALVEAGVDILAFETIPCQKEA 180
Query: 669 EALVEILKEYPNMKAWLSFSCK 734
EALVEILKEYPNMKAWLSFSCK
Sbjct: 181 EALVEILKEYPNMKAWLSFSCK 202
>UniRef50_UPI00015B4DEA Cluster: PREDICTED: similar to homocysteine
S-methyltransferase; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to homocysteine S-methyltransferase -
Nasonia vitripennis
Length = 341
Score = 257 bits (629), Expect = 2e-67
Identities = 115/204 (56%), Positives = 156/204 (76%), Gaps = 1/204 (0%)
Frame = +3
Query: 126 IMSNFEVSSKTVFVLDGGFSTQLTCHAGHTADGDPLWSARFLKTHPQDVINTHLDFLRAG 305
++S E+SS + ++DGGFSTQL H G DGDPLW++RFL ++P V THLD+LRAG
Sbjct: 12 VLSILEISSLSTIIIDGGFSTQLVTHVGEVIDGDPLWTSRFLYSNPDAVFQTHLDYLRAG 71
Query: 306 SDIIETNTYQASVDGFVKHLNLTVEESYELIKSAVEFARTARDLYLQECQESNLSGRKPL 485
S +IET TYQAS+ G+VK+L+ T EE+ +LIK+AVE A+ A +Y +E + ++S +P+
Sbjct: 72 SHVIETATYQASIPGYVKYLDRTEEEALQLIKTAVELAKKAVRVYKEEIKGKDVSNPEPM 131
Query: 486 IAGSVGPYGAYLHDTSEYT-GNYADNTTKETIKNWHRTRIQALVEAGVDILAFETIPCQK 662
+AGS+GPY AYLHD SEYT G+YA+ + ++I WHR R +AL+ GVD+LA ETIPC +
Sbjct: 132 VAGSIGPYAAYLHDCSEYTGGSYANIESMDSIVEWHRPRFEALINGGVDLLAIETIPCAR 191
Query: 663 EAEALVEILKEYPNMKAWLSFSCK 734
EAEALV +LK+YP+ KAWLSFSCK
Sbjct: 192 EAEALVGLLKQYPDTKAWLSFSCK 215
>UniRef50_UPI0000519B36 Cluster: PREDICTED: similar to CG10621-PA;
n=2; Apis mellifera|Rep: PREDICTED: similar to
CG10621-PA - Apis mellifera
Length = 320
Score = 237 bits (581), Expect = 2e-61
Identities = 106/193 (54%), Positives = 141/193 (73%), Gaps = 1/193 (0%)
Frame = +3
Query: 159 VFVLDGGFSTQLTCHAGHTADGDPLWSARFLKTHPQDVINTHLDFLRAGSDIIETNTYQA 338
V +LDGGF QL+ H DGDPLW+++FL T+P V THLDFL+AG+DIIETNTYQA
Sbjct: 3 VKILDGGFGAQLSTHVNEKVDGDPLWTSKFLVTNPNAVYATHLDFLKAGADIIETNTYQA 62
Query: 339 SVDGFVKHLNLTVEESYELIKSAVEFARTARDLYLQECQESN-LSGRKPLIAGSVGPYGA 515
S+ +KHL+++ EES +L+ AV A+TA + Y +E +N + + P+I S GPYGA
Sbjct: 63 SIPSLMKHLSISKEESIKLLHKAVHLAKTAVNDYTKEVINNNDVENKNPMIVASCGPYGA 122
Query: 516 YLHDTSEYTGNYADNTTKETIKNWHRTRIQALVEAGVDILAFETIPCQKEAEALVEILKE 695
LHD SEY G Y T +E I WH++RI A++ AG+D+LA ETIPC +EAEA++E+L+E
Sbjct: 123 SLHDGSEYNGAYGKITPRENIIQWHKSRIDAIINAGIDLLALETIPCYQEAEAIIEVLRE 182
Query: 696 YPNMKAWLSFSCK 734
YPN KAWLSFSC+
Sbjct: 183 YPNTKAWLSFSCE 195
>UniRef50_Q9VJ31 Cluster: CG10623-PA; n=11; Diptera|Rep: CG10623-PA
- Drosophila melanogaster (Fruit fly)
Length = 331
Score = 225 bits (549), Expect = 1e-57
Identities = 107/204 (52%), Positives = 140/204 (68%), Gaps = 1/204 (0%)
Frame = +3
Query: 123 EIMSNFEVSSKTVFVLDGGFSTQLTCHAGHTADGDPLWSARFLKTHPQDVINTHLDFLRA 302
E+ + +K + V GGFS+QL + DGDPLW +RF T+P+ VI THLDFLR
Sbjct: 2 EVNQKWNWDTKPILVKCGGFSSQLAKNVTEKVDGDPLWGSRFDATNPEAVIQTHLDFLRN 61
Query: 303 GSDIIETNTYQASVDGFVKHLNLTVEESYELIKSAVEFARTARDLYLQECQESNLSGRKP 482
G+DII TNTYQ+SV+GFVK+L +T E ELI+ +V+ A+ A++ YL E S P
Sbjct: 62 GADIILTNTYQSSVEGFVKYLGVTRERGVELIQKSVQLAKQAKEQYLSEI-GSEAESALP 120
Query: 483 LIAGSVGPYGAYLHDTSEYTGNYADNTTKETIKNWHRTRIQALVEAGVDILAFETIPCQK 662
LI GS+GPYGAYLHD SEYTGNYAD +KE ++ WH+TRI+ + AGVD LA ET+PC
Sbjct: 121 LIMGSIGPYGAYLHDGSEYTGNYADKMSKEELRAWHKTRIEICLAAGVDGLALETLPCLM 180
Query: 663 EAEALVE-ILKEYPNMKAWLSFSC 731
EAEA+ E +L +P+ K W+S C
Sbjct: 181 EAEAVTELVLDNFPDAKFWVSLQC 204
>UniRef50_Q5PNQ3 Cluster: Novel protein containing a homocysteine
S-methyltransferase domain; n=7; Euteleostomi|Rep: Novel
protein containing a homocysteine S-methyltransferase
domain - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 318
Score = 215 bits (524), Expect = 1e-54
Identities = 104/201 (51%), Positives = 143/201 (71%)
Frame = +3
Query: 126 IMSNFEVSSKTVFVLDGGFSTQLTCHAGHTADGDPLWSARFLKTHPQDVINTHLDFLRAG 305
++S E+ S F+LDGG +T+L +G GDPLWSAR L T PQ + + H +L++G
Sbjct: 2 LISAAEMDSSP-FILDGGLATELEA-SGFQLQGDPLWSARVLHTDPQAIKDVHYRYLQSG 59
Query: 306 SDIIETNTYQASVDGFVKHLNLTVEESYELIKSAVEFARTARDLYLQECQESNLSGRKPL 485
SD+I T TYQAS++GFVK+L + EE+ ++ SAV+ A+ ++ + S+ R+PL
Sbjct: 60 SDVITTATYQASIEGFVKYLGVQPEEAQHMMMSAVQLAKETVSEFISQSPMSDR--REPL 117
Query: 486 IAGSVGPYGAYLHDTSEYTGNYADNTTKETIKNWHRTRIQALVEAGVDILAFETIPCQKE 665
+AGSVGPYG++LHD SEYTG Y D T E +K+WHR +IQ LV+AG D++A ETIP KE
Sbjct: 118 VAGSVGPYGSFLHDGSEYTGAYEDKMTVEELKDWHRPQIQCLVKAGADLVAMETIPGLKE 177
Query: 666 AEALVEILKEYPNMKAWLSFS 728
AEALV++LKE+P KAWLSFS
Sbjct: 178 AEALVKVLKEFPETKAWLSFS 198
>UniRef50_Q4S116 Cluster: Chromosome 1 SCAF14770, whole genome
shotgun sequence; n=4; Euteleostomi|Rep: Chromosome 1
SCAF14770, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 372
Score = 199 bits (486), Expect = 5e-50
Identities = 103/213 (48%), Positives = 138/213 (64%), Gaps = 22/213 (10%)
Frame = +3
Query: 162 FVLDGGFSTQLTCHAGHTADGDPLWSARFLKTHPQDVINTHLDFLRAGSDIIETNTYQAS 341
F+LDGG +T L H GDPLWSAR L T+PQ + + H FL +G+D+I T TYQAS
Sbjct: 17 FILDGGLATDLEAQGVHL-QGDPLWSARLLYTNPQAIRDAHCRFLLSGADVISTATYQAS 75
Query: 342 VDGFVKHLNLTVEESYELIKSAVEFARTARDLYLQECQESNL------------------ 467
V+GF+ HLN++ E + ELI S V+ A+ A + ++ +
Sbjct: 76 VEGFMDHLNVSSEGAKELIMSGVQLAKEAVESFVPGTNPNTTVQSGEGKVNSEGSEGLAG 135
Query: 468 ---SGRK-PLIAGSVGPYGAYLHDTSEYTGNYADNTTKETIKNWHRTRIQALVEAGVDIL 635
SGR+ PL+AGS+GPYGA+LH+ SEYTG+YA+ + + +K WHR +++ L A D+L
Sbjct: 136 QCSSGRRCPLVAGSLGPYGAFLHNGSEYTGDYAEKMSVQELKAWHRPQVECLAAAEADVL 195
Query: 636 AFETIPCQKEAEALVEILKEYPNMKAWLSFSCK 734
AFETIP KEAEALVE+LKE+PN KAWLS SCK
Sbjct: 196 AFETIPSIKEAEALVELLKEFPNTKAWLSLSCK 228
>UniRef50_A7S7I8 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 265
Score = 189 bits (460), Expect = 7e-47
Identities = 93/171 (54%), Positives = 115/171 (67%)
Frame = +3
Query: 222 GDPLWSARFLKTHPQDVINTHLDFLRAGSDIIETNTYQASVDGFVKHLNLTVEESYELIK 401
GDPLWSAR L +P+ V H FL GSDII T TYQAS+ GF KHL +T +E+ +LI+
Sbjct: 5 GDPLWSARVLVENPEAVKQVHKSFLTHGSDIITTATYQASISGFCKHLGVTADEARKLIQ 64
Query: 402 SAVEFARTARDLYLQECQESNLSGRKPLIAGSVGPYGAYLHDTSEYTGNYADNTTKETIK 581
V AR + D + + S P +AGSV PYG D SEY GNY D T + +
Sbjct: 65 RGVHIARESVDEFWDKHSNS------PQVAGSVCPYGTCQSDGSEYHGNYVDTMTIKNLM 118
Query: 582 NWHRTRIQALVEAGVDILAFETIPCQKEAEALVEILKEYPNMKAWLSFSCK 734
+WHR +IQALVE G+D+LAFETIP QKE EALV++LKE+P KAWLS+SCK
Sbjct: 119 DWHRPQIQALVETGLDLLAFETIPAQKEGEALVQLLKEFPGTKAWLSYSCK 169
>UniRef50_Q8LAX0 Cluster: Homocysteine S-methyltransferase 3; n=30;
Magnoliophyta|Rep: Homocysteine S-methyltransferase 3 -
Arabidopsis thaliana (Mouse-ear cress)
Length = 347
Score = 168 bits (408), Expect = 1e-40
Identities = 90/212 (42%), Positives = 135/212 (63%), Gaps = 9/212 (4%)
Frame = +3
Query: 126 IMSNFEVSSKTVFVLDGGFSTQLTCHAGHTADGDPLWSARFLKTHPQDVINTHLDFLRAG 305
+M++F V+DGGF+T+L H DPLWSA+ L T P V HLD+L +G
Sbjct: 12 LMTDFLEKCGGYAVVDGGFATELQRHGADI--NDPLWSAKCLITSPHLVTKVHLDYLESG 69
Query: 306 SDIIETNTYQASVDGFVKHLNLTVEESYELIKSAVEFARTARDLYLQECQESNL------ 467
++II T +YQA++ GFV L+V E+ L++ +VE AR+++ C + +
Sbjct: 70 ANIIITASYQATIQGFVAK-GLSVGEAENLLRRSVEITYEAREIFYNRCTKGSWDFAYAG 128
Query: 468 -SGRKP-LIAGSVGPYGAYLHDTSEYTGNYADNTTKETIKNWHRTRIQALVEAGVDILAF 641
+ R+P L+A SVG YGAYL D SEY+G Y D+ +KET+K++HR R+Q L ++G D++AF
Sbjct: 129 KASRRPILVAASVGSYGAYLADGSEYSGIYGDSVSKETLKDFHRRRVQILAKSGADLIAF 188
Query: 642 ETIPCQKEAEALVEILKEYP-NMKAWLSFSCK 734
ETIP + EAEA ++L+E ++ AW SF+ K
Sbjct: 189 ETIPNKLEAEAYADLLEEEDIDIPAWFSFTSK 220
>UniRef50_Q0TXM4 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 319
Score = 164 bits (399), Expect = 2e-39
Identities = 93/213 (43%), Positives = 136/213 (63%), Gaps = 9/213 (4%)
Frame = +3
Query: 123 EIMSNFEVSSKTVFVLDGGFSTQLTCHAGHTADGDPLWSARFLKTHPQDVINTHLDFLRA 302
+I ++ S ++DG +T L H G G LWSA L + P + THLD+ RA
Sbjct: 5 KISTHLNSSPDIPLLIDGALATYLE-HLGADISGS-LWSASILLSRPDLIKKTHLDYYRA 62
Query: 303 GSDIIETNTYQASVDGFVKHLNLTVEESYELIKSAVEFARTARDLYLQ-----ECQES-- 461
G++I T +YQAS+ G VKHL L E+ +++K +V+ A ARD Y+Q C+ S
Sbjct: 63 GANIAITASYQASIPGLVKHLGLGENEAKDVVKKSVQLAIEARDEYVQSKLEESCERSVD 122
Query: 462 NLSGRKPL-IAGSVGPYGAYLHDTSEYTGNYADNTTKETIKNWHRTRIQALVEAGVDILA 638
S R+ L +AGSVGPYGAYL D SEY G+Y + E +K++HR R+QALV+AGVD+LA
Sbjct: 123 AASLREDLFVAGSVGPYGAYLSDGSEYRGDY--DVAHEAMKDFHRGRVQALVDAGVDVLA 180
Query: 639 FETIPCQKEAEALVEILK-EYPNMKAWLSFSCK 734
ETIP ++E EAL+++L+ E+ + +AW +F+ +
Sbjct: 181 CETIPSRRETEALLDLLQSEFRDAEAWFTFTLR 213
>UniRef50_O31463 Cluster: YbgG protein; n=6; Firmicutes|Rep: YbgG
protein - Bacillus subtilis
Length = 315
Score = 161 bits (390), Expect = 2e-38
Identities = 84/192 (43%), Positives = 121/192 (63%)
Frame = +3
Query: 159 VFVLDGGFSTQLTCHAGHTADGDPLWSARFLKTHPQDVINTHLDFLRAGSDIIETNTYQA 338
+ VLDG +T+L + D LWSA+ L P+ + H D+ AG+D T +YQ+
Sbjct: 13 LIVLDGAMATELERKGCNL--NDSLWSAKILMEEPELIKQVHTDYFAAGADCAITASYQS 70
Query: 339 SVDGFVKHLNLTVEESYELIKSAVEFARTARDLYLQECQESNLSGRKPLIAGSVGPYGAY 518
+ +GF L+ E+ LI+ +V A ARD + +E+ L+ KP+IA S+GPYGAY
Sbjct: 71 TFEGFAAR-GLSEAEARRLIELSVSIAAEARDEFWS-LEENRLNRPKPIIAASIGPYGAY 128
Query: 519 LHDTSEYTGNYADNTTKETIKNWHRTRIQALVEAGVDILAFETIPCQKEAEALVEILKEY 698
L D SEY GNYA +++ + +HR R++AL+EAG D+LA ETIPC EA+A+V +LKE+
Sbjct: 129 LADGSEYRGNYA--ISEDELIEFHRPRMKALIEAGADVLACETIPCLTEAKAIVRLLKEF 186
Query: 699 PNMKAWLSFSCK 734
P AW+SFS K
Sbjct: 187 PETYAWISFSAK 198
>UniRef50_Q47690 Cluster: Homocysteine S-methyltransferase; n=20;
Bacteria|Rep: Homocysteine S-methyltransferase -
Escherichia coli (strain K12)
Length = 310
Score = 150 bits (363), Expect = 4e-35
Identities = 83/197 (42%), Positives = 117/197 (59%)
Frame = +3
Query: 144 VSSKTVFVLDGGFSTQLTCHAGHTADGDPLWSARFLKTHPQDVINTHLDFLRAGSDIIET 323
+ + + +LDG +T+L + AD LWSA+ L +P+ + HLD+ RAG+ T
Sbjct: 11 LDKQDILLLDGAMATELEARGCNLADS--LWSAKVLVENPELIREVHLDYYRAGAQCAIT 68
Query: 324 NTYQASVDGFVKHLNLTVEESYELIKSAVEFARTARDLYLQECQESNLSGRKPLIAGSVG 503
+YQA+ GF L +S LI +VE AR AR+ YL E N L+AGSVG
Sbjct: 69 ASYQATPAGFAAR-GLDEAQSKALIGKSVELARKAREAYLAE----NPQAGTLLVAGSVG 123
Query: 504 PYGAYLHDTSEYTGNYADNTTKETIKNWHRTRIQALVEAGVDILAFETIPCQKEAEALVE 683
PYGAYL D SEY G+Y + + E + +HR R++AL++AG D+LA ET+P E EAL E
Sbjct: 124 PYGAYLADGSEYRGDY--HCSVEAFQAFHRPRVEALLDAGADLLACETLPNFSEIEALAE 181
Query: 684 ILKEYPNMKAWLSFSCK 734
+L YP +AW SF+ +
Sbjct: 182 LLTAYPRARAWFSFTLR 198
>UniRef50_Q3CZT7 Cluster: Homocysteine S-methyltransferase; n=15;
Streptococcus|Rep: Homocysteine S-methyltransferase -
Streptococcus agalactiae H36B
Length = 351
Score = 147 bits (356), Expect = 3e-34
Identities = 81/206 (39%), Positives = 130/206 (63%), Gaps = 4/206 (1%)
Frame = +3
Query: 123 EIMSNFE--VSSKTVFVLDGGFSTQLTCHAGHTADGDPLWSARFLKTHPQDVINTHLDFL 296
++M F+ + SK +L G T+L G G LWS ++L P + H D++
Sbjct: 36 DLMGRFKELLESKKALILHGALGTELESR-GCDVSGK-LWSDKYLIEDPAAIQTIHEDYI 93
Query: 297 RAGSDIIETNTYQASVDGFVKHLNLTVEESYELIKSAVEFARTARDLYLQECQESNLSGR 476
RAG+DI+ T+TYQA++ G + + ++ ++ +LI+ V+ A+ R+ + + S R
Sbjct: 94 RAGADIVTTSTYQATLQGLAQ-VGVSESQAEDLIRLTVQLAKAVREQVWKSLTKEEKSER 152
Query: 477 -KPLIAGSVGPYGAYLHDTSEYTGNYADNTTKETIKNWHRTRIQALVEAGVDILAFETIP 653
PLI+G VGPY A+L D SEYTG Y + KE +KN+HR RI+ L++ GVD+LA ETIP
Sbjct: 153 IYPLISGDVGPYAAFLADGSEYTGLY--DIYKEGLKNFHRHRIELLLDEGVDLLALETIP 210
Query: 654 CQKEAEALVEIL-KEYPNMKAWLSFS 728
+EAEAL+E+L +++P ++A++SF+
Sbjct: 211 NAQEAEALIELLVEDFPQVEAYMSFT 236
>UniRef50_Q4Q0C9 Cluster: Homocysteine S-methyltransferase,
putative; n=3; Leishmania|Rep: Homocysteine
S-methyltransferase, putative - Leishmania major
Length = 339
Score = 142 bits (343), Expect = 1e-32
Identities = 79/191 (41%), Positives = 114/191 (59%), Gaps = 1/191 (0%)
Frame = +3
Query: 159 VFVLDGGFSTQLTCHAGHTADGDPLWSARFLKTHPQDVINTHLDFLRAGSDIIETNTYQA 338
V +LDGG +T+L D PLWS + L PQ + N L +LRAG+ I T +YQ
Sbjct: 30 VVMLDGGLATELETRGCDLRD--PLWSGKVLLESPQQLQNVALAYLRAGARCIITASYQI 87
Query: 339 SVDGFVKHLNLTVEESYELIKSAVEFARTARDLYLQECQESNLSGRKPLIAGSVGPYGAY 518
+ ++H LT + + I+ +V A++AR+ +L+E ++ +AGSVGPYGAY
Sbjct: 88 TPQSLMEHRRLTEDAAVAAIEESVRIAQSARERHLREKPQA----APIFVAGSVGPYGAY 143
Query: 519 LHDTSEYTGNYADNTTKETIKNWHRTRIQALVEAGVDILAFETIPCQKEAEALVEIL-KE 695
L D SEY G+Y + E K +HR RI AL+ AG D+LA ET P E A+V +L +E
Sbjct: 144 LADGSEYRGDYV--RSAEEFKEFHRLRIAALLRAGADVLAIETQPSAAEVRAIVALLQEE 201
Query: 696 YPNMKAWLSFS 728
+PN +AW+SF+
Sbjct: 202 HPNCRAWVSFT 212
>UniRef50_A3TGH3 Cluster: Homocysteine methyltransferase; n=1;
Janibacter sp. HTCC2649|Rep: Homocysteine
methyltransferase - Janibacter sp. HTCC2649
Length = 305
Score = 130 bits (313), Expect = 5e-29
Identities = 82/189 (43%), Positives = 113/189 (59%), Gaps = 1/189 (0%)
Frame = +3
Query: 165 VLDGGFSTQLTCHAGHTADGDPLWSARFLKTHPQDVINTHLDFLRAGSDIIETNTYQASV 344
VLDGGFST L GH G LWSAR L+ P +V+ H F+ AG++I+ + +YQAS
Sbjct: 24 VLDGGFSTALEAR-GHDLSGR-LWSARLLRQAPSEVVAAHRTFVDAGAEIVISASYQASH 81
Query: 345 DGFVKHLNLTVEESYELIKSAVEFARTARDLYLQECQESNLSGRKPLIAGSVGPYGAYLH 524
G+V LT EE + +++E AR D GR L+A SVGPYGA+L
Sbjct: 82 AGYVA-AGLTEEECDADLDASIELARQGAD------------GR-ALVAASVGPYGAHLA 127
Query: 525 DTSEYTGNYADNTTKETIKNWHRTRIQALVEAGVDILAFETIPCQKEAEALVEILKEY-P 701
D SEYTG A ++ T++ +H R++ L+ AG D++A ETIP EAE +VE+L E P
Sbjct: 128 DGSEYTGYPA--VSRATLREFHSRRLERLIAAGPDLVAVETIPEVAEAEVVVELLTEIAP 185
Query: 702 NMKAWLSFS 728
++ W+SFS
Sbjct: 186 DLPYWVSFS 194
>UniRef50_Q88XC1 Cluster: Homocysteine S-methyltransferase; n=2;
Bacteria|Rep: Homocysteine S-methyltransferase -
Lactobacillus plantarum
Length = 309
Score = 128 bits (308), Expect = 2e-28
Identities = 78/204 (38%), Positives = 115/204 (56%), Gaps = 1/204 (0%)
Frame = +3
Query: 126 IMSNFEVSSKTVFVLDGGFSTQLTCHAGHTADGDPLWSARFLKTHPQDVINTHLDFLRAG 305
++S E ++ V DG +T+L A LWSA + HP + H +L AG
Sbjct: 1 MLSLTEQLNRGPVVSDGAMATELEKRG--VATNSALWSATAMLDHPDAIQAVHQSYLDAG 58
Query: 306 SDIIETNTYQASVDGFVKHLNLTVEESYELIKSAVEFARTARDLYLQECQESNLSGRKPL 485
+ I+ TNTYQA+V F + + ++ +LI+ AV A TARD S+++ +
Sbjct: 59 AKIMTTNTYQANVPAF-EQAGIAAVQARQLIQQAVTIAHTARD-------ASHVT--DAV 108
Query: 486 IAGSVGPYGAYLHDTSEYTGNYADNTTKETIKNWHRTRIQALVEAGVDILAFETIPCQKE 665
IAGS+GPYGAYL D SEYTG Y T +++HR R+ ++ AGVD+LA ET+P E
Sbjct: 109 IAGSIGPYGAYLADGSEYTGAY--QLTPSAYQDFHRERLALIMAAGVDVLALETMPRLDE 166
Query: 666 AEALVEIL-KEYPNMKAWLSFSCK 734
+ALV+++ +P W+SFS K
Sbjct: 167 VQALVQLITTTWPQQPYWVSFSIK 190
>UniRef50_Q7D740 Cluster: Homocysteine S-methyltransferase; n=14;
Actinomycetales|Rep: Homocysteine S-methyltransferase -
Mycobacterium tuberculosis
Length = 302
Score = 128 bits (308), Expect = 2e-28
Identities = 79/196 (40%), Positives = 110/196 (56%)
Frame = +3
Query: 141 EVSSKTVFVLDGGFSTQLTCHAGHTADGDPLWSARFLKTHPQDVINTHLDFLRAGSDIIE 320
E+ S +V + DGG +T+L GH DPLWSAR L P + H + RAG+ I
Sbjct: 2 ELVSDSVLISDGGLATELEAR-GHDLS-DPLWSARLLVDAPHAITAVHTAYFRAGAQIAT 59
Query: 321 TNTYQASVDGFVKHLNLTVEESYELIKSAVEFARTARDLYLQECQESNLSGRKPLIAGSV 500
T +YQAS +GF + +++ L++ +VE A+ ARD E LS +A SV
Sbjct: 60 TASYQASFEGFAAR-GIGHDDATVLLRRSVELAQAARD----EVGVGGLS-----VAASV 109
Query: 501 GPYGAYLHDTSEYTGNYADNTTKETIKNWHRTRIQALVEAGVDILAFETIPCQKEAEALV 680
GPYGA L D SEY G Y + + WH R++ LV+AG D+LA +TIP EAEALV
Sbjct: 110 GPYGAALADGSEYRGCY--GLSVAALMKWHLPRLEVLVDAGADMLALKTIPDIDEAEALV 167
Query: 681 EILKEYPNMKAWLSFS 728
+++ AWLS++
Sbjct: 168 NLVRRLAT-PAWLSYT 182
>UniRef50_Q1GBT8 Cluster: Homocysteine S-methyltransferase; n=2;
Lactobacillus delbrueckii subsp. bulgaricus|Rep:
Homocysteine S-methyltransferase - Lactobacillus
delbrueckii subsp. bulgaricus (strain ATCC 11842 /
DSM20081)
Length = 310
Score = 124 bits (298), Expect = 3e-27
Identities = 76/190 (40%), Positives = 111/190 (58%), Gaps = 1/190 (0%)
Frame = +3
Query: 168 LDGGFSTQLTCHAGHTADGDPLWSARFLKTHPQDVINTHLDFLRAGSDIIETNTYQASVD 347
LDG ST L G + D LW+A+ L +P V H ++ +AG+ + T++YQAS+
Sbjct: 15 LDGSMSTPLEAW-GEDTNSD-LWTAKALADNPDLVYRVHQEYFKAGARVTITDSYQASLP 72
Query: 348 GFVKHLNLTVEESYELIKSAVEFARTARDLYLQECQESNLSGRKPLIAGSVGPYGAYLHD 527
F+KH L+ + + LI+ + A ARD + +E +G +AGSVGPYGAYL D
Sbjct: 73 AFMKH-GLSEDAARALIRESAAVAIKARDDFEKE------TGIHNFVAGSVGPYGAYLAD 125
Query: 528 TSEYTGNYADNTTKETIKNWHRTRIQALVEAGVDILAFETIPCQKEAEALVEILK-EYPN 704
SEY G+YA + E ++H RI+ LV GVD LA ET P E A+++ LK +YP+
Sbjct: 126 GSEYRGDYA--LSHEEYVDFHAPRIEELVAGGVDCLAVETQPKLSEVRAILDYLKAKYPD 183
Query: 705 MKAWLSFSCK 734
+ ++SFS K
Sbjct: 184 LPVYVSFSLK 193
>UniRef50_A5CB34 Cluster: Putative uncharacterized protein; n=1;
Vitis vinifera|Rep: Putative uncharacterized protein -
Vitis vinifera (Grape)
Length = 347
Score = 118 bits (283), Expect = 2e-25
Identities = 74/171 (43%), Positives = 102/171 (59%), Gaps = 20/171 (11%)
Frame = +3
Query: 282 HLDFLRAGSDIIETNTYQA-SVDGFVKHL---NLTVEESYE-----LIKSAVEFARTARD 434
HLD+L AG+DII T +YQ S +V L L +E S E + +VE A AR
Sbjct: 90 HLDYLEAGADIIITASYQVNSAYIYVNRLLFRGLKLEASLEEKVKPCLGKSVEIACEARK 149
Query: 435 LYLQEC--------QESNLSGRKP-LIAGSVGPYGAYLHDTSEYTGNYADNTTKETIKNW 587
+Y C ++ + +P L+A SVG YGAYL D SEY+G Y D T ET+K++
Sbjct: 150 MYYDRCIEFACDDXEDGRILKHRPILVAASVGSYGAYLADGSEYSGIYGDEITVETLKDF 209
Query: 588 HRTRIQALVEAGVDILAFETIPCQKEAEALVEILKEYPNMK--AWLSFSCK 734
HR R+Q L +AG D++AFET+P + EA+A E+L+E N+K AW SF+ K
Sbjct: 210 HRRRVQILADAGADLIAFETVPNKLEAQAYAELLEE-ENIKIPAWFSFNSK 259
Score = 40.3 bits (90), Expect = 0.048
Identities = 30/85 (35%), Positives = 44/85 (51%)
Frame = +3
Query: 129 MSNFEVSSKTVFVLDGGFSTQLTCHAGHTADGDPLWSARFLKTHPQDVINTHLDFLRAGS 308
+S+F + + V V+DGG +T+L H DPLWSA+ L + P HL +R GS
Sbjct: 12 ISDFLLQTGGVAVIDGGLATELERHGADL--NDPLWSAKCLLSSP------HL--IRTGS 61
Query: 309 DIIETNTYQASVDGFVKHLNLTVEE 383
+ Y + G VK+ N+ V E
Sbjct: 62 RFVNLGWYSLRLLG-VKNQNVAVWE 85
>UniRef50_Q0BQM8 Cluster: Homocysteine S-methyltransferase; n=1;
Granulibacter bethesdensis CGDNIH1|Rep: Homocysteine
S-methyltransferase - Granulobacter bethesdensis (strain
ATCC BAA-1260 / CGDNIH1)
Length = 313
Score = 116 bits (279), Expect = 6e-25
Identities = 70/191 (36%), Positives = 106/191 (55%), Gaps = 1/191 (0%)
Frame = +3
Query: 165 VLDGGFSTQLTCHAGHTADGDPLWSARFLKTHPQDVINTHLDFLRAGSDIIETNTYQASV 344
+LDG +T+L AG+ D DPLWS R L +P + H +L AG+D IET +YQ S+
Sbjct: 16 LLDGALATELE-RAGYHLD-DPLWSGRLLLDNPAAIAAVHRAYLEAGADCIETASYQLSL 73
Query: 345 DGFVKHLNLTVEESYELIKSAVEFARTARDLYLQECQESNLSGR-KPLIAGSVGPYGAYL 521
G ++ L+ + ++ A A + RD + R +PL+AGS+GPYGA
Sbjct: 74 PG-LQRRGLSRGRAMSVLADAARLACSVRDDVWAGLPAAQRRNRIRPLVAGSLGPYGACQ 132
Query: 522 HDTSEYTGNYADNTTKETIKNWHRTRIQALVEAGVDILAFETIPCQKEAEALVEILKEYP 701
D SEYTG YA ++ +H R++AL G D++A ET+P EA A ++L+
Sbjct: 133 ADGSEYTGRYA--LSRSQYLAFHAPRMRALAAGGADLIACETVPHLDEALAFADLLQAL- 189
Query: 702 NMKAWLSFSCK 734
++ W+SFS +
Sbjct: 190 SVPGWVSFSVR 200
>UniRef50_A6G853 Cluster: Homocysteine methyltransferase; n=1;
Plesiocystis pacifica SIR-1|Rep: Homocysteine
methyltransferase - Plesiocystis pacifica SIR-1
Length = 325
Score = 115 bits (276), Expect = 1e-24
Identities = 74/177 (41%), Positives = 99/177 (55%)
Frame = +3
Query: 165 VLDGGFSTQLTCHAGHTADGDPLWSARFLKTHPQDVINTHLDFLRAGSDIIETNTYQASV 344
VLDGG +T L G D DPLWSAR L P+ + H + AG+DI+ T +YQAS+
Sbjct: 22 VLDGGLATSLEA-CGCDLD-DPLWSARLLLDDPEALRTVHRRWRDAGADILATASYQASL 79
Query: 345 DGFVKHLNLTVEESYELIKSAVEFARTARDLYLQECQESNLSGRKPLIAGSVGPYGAYLH 524
G ++ L+ + L++ +V R A D E+N +PLIA SVG YGAYL
Sbjct: 80 PG-LRAKGLSEARAKALLRESVTLTRAAAD-------EAN--APRPLIAASVGSYGAYLA 129
Query: 525 DTSEYTGNYADNTTKETIKNWHRTRIQALVEAGVDILAFETIPCQKEAEALVEILKE 695
D SEY G Y + E + ++HR R+ L AG D++AFET P E AL E+L E
Sbjct: 130 DGSEYRGGY--GLSVEALADFHRPRLLELAAAGPDLIAFETFPDAVELAALAELLTE 184
>UniRef50_UPI000050FD2A Cluster: COG2040:
Homocysteine/selenocysteine methylase
(S-methylmethionine-dependent); n=1; Brevibacterium
linens BL2|Rep: COG2040: Homocysteine/selenocysteine
methylase (S-methylmethionine-dependent) -
Brevibacterium linens BL2
Length = 308
Score = 114 bits (275), Expect = 2e-24
Identities = 76/193 (39%), Positives = 100/193 (51%)
Frame = +3
Query: 144 VSSKTVFVLDGGFSTQLTCHAGHTADGDPLWSARFLKTHPQDVINTHLDFLRAGSDIIET 323
V S V+DGG T L + LWSA L+ P + H DF+RAG+ I+ T
Sbjct: 13 VRSGDPLVIDGGLGTALESRGIDLSH--ELWSAALLRDSPDTLAEVHADFIRAGAQIVTT 70
Query: 324 NTYQASVDGFVKHLNLTVEESYELIKSAVEFARTARDLYLQECQESNLSGRKPLIAGSVG 503
+YQA+ GF + ++ EE LI +VE A A D L+AGSVG
Sbjct: 71 ASYQATPLGF-ERASIPAEEGLRLIARSVEIAAGAGDA---------------LVAGSVG 114
Query: 504 PYGAYLHDTSEYTGNYADNTTKETIKNWHRTRIQALVEAGVDILAFETIPCQKEAEALVE 683
PYGA L + +EYTG+Y + + E +HR RI+ALV AG D+LA ET P E L
Sbjct: 115 PYGAALGNGAEYTGDY--HLSDEEFAAFHRPRIEALVNAGADLLAIETQPSLSEITVLAG 172
Query: 684 ILKEYPNMKAWLS 722
+ EY + AWLS
Sbjct: 173 LADEY-GIPAWLS 184
>UniRef50_A5VKC8 Cluster: Homocysteine S-methyltransferase; n=2;
Lactobacillus reuteri|Rep: Homocysteine
S-methyltransferase - Lactobacillus reuteri F275
Length = 310
Score = 114 bits (274), Expect = 2e-24
Identities = 70/191 (36%), Positives = 110/191 (57%), Gaps = 1/191 (0%)
Frame = +3
Query: 165 VLDGGFSTQLTCHAGHTADGDPLWSARFLKTHPQDVINTHLDFLRAGSDIIETNTYQASV 344
++DG ST L T + LW+A L P V H ++ +AG + T+TYQA+V
Sbjct: 13 LIDGAMSTALEQLGADT--NNSLWTASVLANQPALVKKVHQEYFKAGDRLAITDTYQANV 70
Query: 345 DGFVKHLNLTVEESYELIKSAVEFARTARDLYLQECQESNLSGRKPLIAGSVGPYGAYLH 524
F+K+ + +E++ LI+ AV A+ ARD Y QE +G +AG++GPYGAYL
Sbjct: 71 PAFIKN-GYSKQEAHSLIQRAVVLAKEARDEYQQE------TGIYNYVAGALGPYGAYLA 123
Query: 525 DTSEYTGNYADNTTKETIKNWHRTRIQALVEAGVDILAFETIPCQKEAEALVEILKEY-P 701
+ SEY+G Y +T + + +HR R+ ++ GVD++A ET P E A ++++KE P
Sbjct: 124 NGSEYSGAYHLSTIE--YQQFHRPRLTDILTVGVDVIAIETQPRLDEVLAELDLVKELAP 181
Query: 702 NMKAWLSFSCK 734
+ ++SFS K
Sbjct: 182 DTLCYVSFSLK 192
>UniRef50_Q49V93 Cluster: Putative homocysteine S-methyltransferase;
n=1; Staphylococcus saprophyticus subsp. saprophyticus
ATCC 15305|Rep: Putative homocysteine
S-methyltransferase - Staphylococcus saprophyticus
subsp. saprophyticus (strain ATCC 15305 /DSM 20229)
Length = 301
Score = 112 bits (269), Expect = 1e-23
Identities = 73/195 (37%), Positives = 108/195 (55%), Gaps = 1/195 (0%)
Frame = +3
Query: 141 EVSSKTVFVLDGGFSTQLTCHAGHTADGDPLWSARFLKTHPQDVINTHLDFLRAGSDIIE 320
++ +++ VLDGG +T L AG + LWS+ LK +P + H F G+DI+
Sbjct: 6 KLKAQSPLVLDGGLATTLE-QAGCSLKTS-LWSSEVLKNNPTQIKQAHQAFTDVGADILL 63
Query: 321 TNTYQASVDGFVKHLNLTVEESYELIKSAVEFARTARDLYLQECQESNLSGRKPLIAGSV 500
T+TYQAS F + + E +L +AV + E+ + +I GS+
Sbjct: 64 TSTYQASYQTF-SDIGMKATEIDQLYNTAVN-----------QIMEATTDTQ--VIVGSL 109
Query: 501 GPYGAYLHDTSEYTGNYADNTTKETIKNWHRTRIQALVEAGVDILAFETIPCQKEAEALV 680
GPYGAYL D SEYTG Y + +KE +H+TRI+ALV+ G++ FET+P +E +A+V
Sbjct: 110 GPYGAYLSDGSEYTGAY--DLSKEDYFQFHKTRIEALVKRGINDFVFETVPNFEEIKAIV 167
Query: 681 E-ILKEYPNMKAWLS 722
E I+ Y N WLS
Sbjct: 168 EYIVPHYTNQTFWLS 182
>UniRef50_Q5FKC1 Cluster: Homocysteine S-methyltransferase; n=2;
Lactobacillus|Rep: Homocysteine S-methyltransferase -
Lactobacillus acidophilus
Length = 310
Score = 110 bits (264), Expect = 4e-23
Identities = 69/180 (38%), Positives = 102/180 (56%)
Frame = +3
Query: 165 VLDGGFSTQLTCHAGHTADGDPLWSARFLKTHPQDVINTHLDFLRAGSDIIETNTYQASV 344
+LDG ST L +T + LW+A L+ V H+++ ++G+ + TNTYQA+V
Sbjct: 13 ILDGAMSTALEKQGVNT--NNDLWTAVALENDLDKVYKVHMNYFKSGAQMTITNTYQANV 70
Query: 345 DGFVKHLNLTVEESYELIKSAVEFARTARDLYLQECQESNLSGRKPLIAGSVGPYGAYLH 524
F KH + E + +LI AV+ A+ ARD Y + +G+ +A SVGPYGAYL
Sbjct: 71 QAFKKH-GYSDEHTKKLITDAVQIAKKARDDYQTQ------TGKHNWVAASVGPYGAYLS 123
Query: 525 DTSEYTGNYADNTTKETIKNWHRTRIQALVEAGVDILAFETIPCQKEAEALVEILKEYPN 704
D E+ G+Y+ T KE + +H R++ L+E D LA ET P E A+++ LKEY N
Sbjct: 124 DGDEFRGDYS-LTPKEYLA-FHLPRLKILLENKPDCLAIETQPKLDEVIAILDWLKEYAN 181
>UniRef50_A5DTG6 Cluster: Putative uncharacterized protein; n=1;
Lodderomyces elongisporus NRRL YB-4239|Rep: Putative
uncharacterized protein - Lodderomyces elongisporus
(Yeast) (Saccharomyces elongisporus)
Length = 326
Score = 107 bits (257), Expect = 3e-22
Identities = 71/198 (35%), Positives = 106/198 (53%), Gaps = 10/198 (5%)
Frame = +3
Query: 165 VLDGGFSTQLTC----HAGHTADGDPLWSARFLKTHPQDVINTHLDFLRAGSDIIETNTY 332
VLDG T L A + PLWS + L P+ + H ++ AGS++I T+TY
Sbjct: 11 VLDGALGTALEDLIDPSAPYLPSKSPLWSGQVLLDAPELIQKVHEMYIGAGSEVIFTSTY 70
Query: 333 QASVDGFVKHLNLTVEESYELIKSAVEFARTAR---DLYLQECQESNLSGR--KPLIAGS 497
Q S D KH L+ E+ E+ + +++ R A D + +E G K IAGS
Sbjct: 71 QLSYDSLRKHTTLSDEQILEVWQRSIDLVRAAALSIDETARYTKEKESRGEPGKVHIAGS 130
Query: 498 VGPYGAYLHDTSEYTGNYADNTTKETIKNWHRTRIQALVE-AGVDILAFETIPCQKEAEA 674
+GPY AYL + SEYTG+Y N T E ++ +H ++ E VD++AFETIP +E +A
Sbjct: 131 IGPYAAYLANGSEYTGDYG-NVTDEQLEAFHTPMLEFFTENEAVDLIAFETIPNFQELKA 189
Query: 675 LVEILKEYPNMKAWLSFS 728
+ +++K N K + FS
Sbjct: 190 VTKLVKRL-NCKKPVLFS 206
>UniRef50_Q59QD2 Cluster: Putative uncharacterized protein SAM4;
n=1; Candida albicans|Rep: Putative uncharacterized
protein SAM4 - Candida albicans (Yeast)
Length = 311
Score = 102 bits (245), Expect = 8e-21
Identities = 62/201 (30%), Positives = 105/201 (52%), Gaps = 5/201 (2%)
Frame = +3
Query: 141 EVSSKTVFVLDGGFSTQLT----CHAGHTADGDPLWSARFLKTHPQDVINTHLDFLRAGS 308
++ K V+DG T+L + + G PLWS + L +P+ V HLD++ G+
Sbjct: 6 DILDKRKLVIDGALGTELERLLPTTSTYLPSGSPLWSGQVLIKNPELVEQVHLDYINVGA 65
Query: 309 DIIETNTYQASVDGFVKHLNLTVEESYELIKSAVEFARTARDLYLQECQESNLSGRKP-L 485
D+I T+TYQ S K++ ++++ L SA+ A+ A SGR +
Sbjct: 66 DMIITSTYQTSYASLHKYIGYDMDQAIALWNSALNVAKNA----------VKKSGRDDVI 115
Query: 486 IAGSVGPYGAYLHDTSEYTGNYADNTTKETIKNWHRTRIQALVEAGVDILAFETIPCQKE 665
IAGS+GPY L + SEY G+Y T +E I+ +H + + VDI+ ETIP +E
Sbjct: 116 IAGSIGPYATLLANGSEYNGDYQGVTDEELIE-YHTPLFEFYENSDVDIICIETIPSFQE 174
Query: 666 AEALVEILKEYPNMKAWLSFS 728
+ ++ + K+Y + + ++S +
Sbjct: 175 LKVIIGLAKKYTSKEFFISIN 195
>UniRef50_Q6BZK6 Cluster: Debaryomyces hansenii chromosome A of
strain CBS767 of Debaryomyces hansenii; n=1;
Debaryomyces hansenii|Rep: Debaryomyces hansenii
chromosome A of strain CBS767 of Debaryomyces hansenii -
Debaryomyces hansenii (Yeast) (Torulaspora hansenii)
Length = 351
Score = 100 bits (240), Expect = 3e-20
Identities = 63/190 (33%), Positives = 101/190 (53%), Gaps = 13/190 (6%)
Frame = +3
Query: 165 VLDGGFSTQLTCHAGHTADGD-------PLWSARFLKTHPQDVINTHLDFLRAGSDIIET 323
V+DG TQL D PLWSA L +P+ + H D++ +G++II T
Sbjct: 15 VIDGALGTQLETKFSKLLQQDNINIQTHPLWSALVLLKNPELIQEVHYDYMCSGANIITT 74
Query: 324 NTYQASVDGFVKHLN--LTVEESYELIKSAVEFARTARDLYLQECQE--SNLSGRKPLIA 491
+TYQAS G +++ +E + A+E A AR YL+ + + L+ ++ I
Sbjct: 75 STYQASKRGLLEYAPGIENDDEVNAVYDKAIELAVDARSQYLENMGKGMNTLTNKEIFIC 134
Query: 492 GSVGPYGAYLHDTSEYTGNYADNTTK-ETIKNWH-RTRIQALVEAGVDILAFETIPCQKE 665
GS+GP+GAYL + +EYTG Y + T+ + +K +H Q + DI+ FETIP E
Sbjct: 135 GSIGPFGAYLANGAEYTGKYGSHITEPQELKKFHYDITSQFISNPKCDIIGFETIPNYSE 194
Query: 666 AEALVEILKE 695
+ +V +++E
Sbjct: 195 FQQIVHLMEE 204
>UniRef50_A3LQC9 Cluster: AdoMet-homocysteine methyltransferase;
n=1; Pichia stipitis|Rep: AdoMet-homocysteine
methyltransferase - Pichia stipitis (Yeast)
Length = 337
Score = 93.9 bits (223), Expect = 4e-18
Identities = 62/194 (31%), Positives = 101/194 (52%), Gaps = 6/194 (3%)
Frame = +3
Query: 126 IMSNFEVSSKTVFVLDGGFSTQLTCHAGHTAD----GDPLWSARFLKTHPQDVINTHLDF 293
++S E SK VLDG T+L + PLWS L P + N H ++
Sbjct: 1 MLSLKEALSKNRLVLDGAMGTELEACIPKDSKIQPRKHPLWSGLVLLNEPNLIKNVHYNY 60
Query: 294 L-RAGSDIIETNTYQASVDGFVKHLNLTVEESYELIKSAVEFARTARDLYLQECQESNLS 470
L +A D + ++TYQ S +H +L E+ + K +++ D LQ +++ S
Sbjct: 61 LEQADVDALISSTYQISYPSLKEHTDLDDEQIRGIWKKSID---VVEDAILQYRSKNSNS 117
Query: 471 GRKPLIAGSVGPYGAYLHDTSEYTGNYADNTTKETIKNWHRTRIQ-ALVEAGVDILAFET 647
+K I GS+GPY YL D SEYTG+Y N + I+++H+ ++ L + VD + FET
Sbjct: 118 KKKIYIIGSIGPYATYLADGSEYTGDY-KNASDSDIESYHQPLLEYFLGDDRVDTIGFET 176
Query: 648 IPCQKEAEALVEIL 689
IP +E + ++++L
Sbjct: 177 IPSFQEVKVVLKLL 190
>UniRef50_A5DCB0 Cluster: Putative uncharacterized protein; n=1;
Pichia guilliermondii|Rep: Putative uncharacterized
protein - Pichia guilliermondii (Yeast) (Candida
guilliermondii)
Length = 313
Score = 93.1 bits (221), Expect = 6e-18
Identities = 64/179 (35%), Positives = 87/179 (48%), Gaps = 4/179 (2%)
Frame = +3
Query: 165 VLDGGFSTQLTCHA---GHTADGDPLWSARFLKTHPQDVINTHLDFLRAGSDIIETNTYQ 335
VLDGG QL A DPLWS R L P + + H FL AG DI+ T+TYQ
Sbjct: 8 VLDGGLGIQLETLAEKRNFAVKNDPLWSGRALIEAPDLIEDVHKSFLEAGCDIVTTSTYQ 67
Query: 336 ASVDGFVKHLNLTVEESYELIKSAVEFARTARDLYLQECQESNLSGRKPLIAGSVGPYGA 515
S K+ + T + EL +V D+ Q C+ R + G++GPYG
Sbjct: 68 ISRASLKKYTDFTDAQIEELWAKSV-------DVCWQACKFHESKAR---VCGAIGPYGG 117
Query: 516 YLHDTSEYTGNYADNTTKETIKNWHRTRIQAL-VEAGVDILAFETIPCQKEAEALVEIL 689
+L + +EYTG Y T ++ +H L VDILAFETIP KE + +V ++
Sbjct: 118 FLANYAEYTGEYG-LITNHKLEQYHLPLATFLNNNPKVDILAFETIPNYKELKVIVNLV 175
>UniRef50_Q2TXK9 Cluster: Predicted protein; n=2;
Trichocomaceae|Rep: Predicted protein - Aspergillus
oryzae
Length = 376
Score = 82.6 bits (195), Expect = 9e-15
Identities = 62/184 (33%), Positives = 91/184 (49%), Gaps = 11/184 (5%)
Frame = +3
Query: 159 VFVLDGGFSTQL---TCHAGHTADGDPLWSARFLKTHPQDVINTHLDFLRAGSDIIETNT 329
+ +LDGG T L + TA+ PLWSA L + P + H F G+DII T T
Sbjct: 8 ILLLDGGLGTTLGDPPHNITFTAE-TPLWSAHLLISSPSTLEEVHKAFATVGADIILTAT 66
Query: 330 YQASVDGF-VKHLNLTVEESYELIKSAVEFARTARDLYLQECQESNLSGRKPLIAGSVGP 506
YQ S +GF + T +++ ++SA+ AR A + SGR +A S+GP
Sbjct: 67 YQTSFEGFTLTDPRYTADDAAHFMRSAIPLARRA----------GSSSGRTVKVALSLGP 116
Query: 507 YGAYLHDT-SEYTGNYADNTTKET-IKNWHRTRIQALV-EAG----VDILAFETIPCQKE 665
YGA + +EYTG Y + E ++ WH R+ V E G + +AFET+ E
Sbjct: 117 YGATMSPVGAEYTGLYPEEMNSEAKLREWHARRLCVFVDETGSWDNFEYIAFETVRRADE 176
Query: 666 AEAL 677
+A+
Sbjct: 177 VKAI 180
>UniRef50_Q7SFT2 Cluster: Putative uncharacterized protein
NCU00799.1; n=1; Neurospora crassa|Rep: Putative
uncharacterized protein NCU00799.1 - Neurospora crassa
Length = 361
Score = 81.0 bits (191), Expect = 3e-14
Identities = 59/186 (31%), Positives = 95/186 (51%), Gaps = 9/186 (4%)
Frame = +3
Query: 159 VFVLDGGFSTQLT-CHAGHTADGDPLWSARFLKTHPQDVINT-HLDFLRAGSDIIETNTY 332
V +LDGG T L H + PLWS+ L + +D ++ H F +AG++II T TY
Sbjct: 7 VQILDGGMGTTLEDMHDITFSFETPLWSSHLLVSGEEDKLSDCHEAFKQAGANIISTATY 66
Query: 333 QASVDGFVKHL---NLTVEESYELIKSAVEFARTARDLYLQECQESNLSGRKPLIAGSVG 503
Q S++GF + TV+E E +E R L +N +G + +A S+G
Sbjct: 67 QISINGFAATKAPRSGTVDEERE----GIEKEEIPRFLSRAVVLAANAAGTEGKVALSLG 122
Query: 504 PYGAYLHDTSEYTGNY-ADNTTKETIKNWHRTRIQALVEAG---VDILAFETIPCQKEAE 671
PYGA + ++EY+G Y ++ + + WH+ R+ + V+ +AFET+P E
Sbjct: 123 PYGATMIPSTEYSGRYDPEHQHVQALGKWHKERLDLFKDVDPNQVNYIAFETVPRLDEIV 182
Query: 672 ALVEIL 689
A+ +L
Sbjct: 183 AIRNLL 188
>UniRef50_Q6C0D6 Cluster: Yarrowia lipolytica chromosome F of strain
CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome F of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 348
Score = 81.0 bits (191), Expect = 3e-14
Identities = 48/136 (35%), Positives = 77/136 (56%)
Frame = +3
Query: 282 HLDFLRAGSDIIETNTYQASVDGFVKHLNLTVEESYELIKSAVEFARTARDLYLQECQES 461
H D++ AG+DI+ + +YQAS++G +K + + A+ R + L + E+
Sbjct: 83 HKDYVVAGADIVTSASYQASLEGTIK------AGAVQRWPEALWMLRKSEQLVRKAVTEA 136
Query: 462 NLSGRKPLIAGSVGPYGAYLHDTSEYTGNYADNTTKETIKNWHRTRIQALVEAGVDILAF 641
+ RK L+A SVGP+GA+L EY G+Y TK+ I+ H +I+A++ D+L
Sbjct: 137 KVK-RKVLLAASVGPFGAWLGGGQEYNGDYT-GYTKDDIRRHHEFKIRAVLGGSPDMLLI 194
Query: 642 ETIPCQKEAEALVEIL 689
ETIP E E LV++L
Sbjct: 195 ETIPSIIEVEVLVDVL 210
>UniRef50_Q4PDM6 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 448
Score = 81.0 bits (191), Expect = 3e-14
Identities = 64/205 (31%), Positives = 99/205 (48%), Gaps = 28/205 (13%)
Frame = +3
Query: 144 VSSKTVFVLDGGFSTQLTCHAGHTADGDPLWSARFLKTHPQDV---------INTHLDFL 296
+S + +LDGG +T L PLWSAR L DV + HL +L
Sbjct: 14 LSPARIGILDGGLATYLEDGLDFDLSKGPLWSARLLDEKEDDVSDGKGQKGIFDAHLHYL 73
Query: 297 RAGSDIIETNTYQASVDGFVKHLNLTVEESYELIKSAVEFARTA---RDLYLQECQESNL 467
+AG+ II T TYQAS++ F + N + L+ AV+ A A ++ + ++
Sbjct: 74 QAGAGIIGTATYQASLESFAR-ANYDQVSASHLMSKAVDLACDALHAHNISNNKVGVASA 132
Query: 468 SGRKPLIAGSVGPYGAYLHDTSEYTGNY------------ADNTTKETIKNWHRTRIQAL 611
+ +PL++ S+GPYGA L + +EYTG+Y + E + +H+ RI+A
Sbjct: 133 ASARPLLSLSLGPYGAMLSNGAEYTGDYRRTFLAESDPLREQQPSLEEMMAFHQRRIEAF 192
Query: 612 VE----AGVDILAFETIPCQKEAEA 674
+ V +LA ET+P EA A
Sbjct: 193 IAQPSWEHVGVLAVETVPRADEALA 217
>UniRef50_A6S563 Cluster: Putative uncharacterized protein; n=2;
Sclerotiniaceae|Rep: Putative uncharacterized protein -
Botryotinia fuckeliana B05.10
Length = 369
Score = 80.2 bits (189), Expect = 5e-14
Identities = 66/200 (33%), Positives = 95/200 (47%), Gaps = 18/200 (9%)
Frame = +3
Query: 159 VFVLDGGFSTQL-TCHAGHTADGDPLWSARFL-KTHP---QDVINTHLDFLRAGSDIIET 323
+ +LDGG T L H + +PLWS++ L THP + ++ T F+ AG+DI+ T
Sbjct: 7 IHLLDGGLGTTLGDSHQVQFTEKEPLWSSQLLIPTHPHGPKTLLATQKSFVDAGADILLT 66
Query: 324 NTYQASVDGF------VKHLNLTVEESYELIKSAVE-FARTARDLYLQECQESNLSGRKP 482
TYQ S +GF V + + + K V R+A D+ S K
Sbjct: 67 ATYQTSYEGFGGSGYAVHSHSSSNSGKADGDKEEVNGIMRSAVDIASDAFSTKKDSNGK- 125
Query: 483 LIAGSVGPYGAYLHDTSEYTGNY-ADNTTKETIKNWHRTRIQALVE-----AGVDILAFE 644
IA S+G YGA + EYTG Y D+ + E + +WH RI VD +AFE
Sbjct: 126 -IALSLGAYGAIMTPGQEYTGKYDDDHKSSEQLSSWHHERISVFSRDPKCWERVDYVAFE 184
Query: 645 TIPCQKEAEALVEILKEYPN 704
TIP +E E + + + E N
Sbjct: 185 TIPLLEEIEGVRKSMGEVEN 204
>UniRef50_UPI0000E4900F Cluster: PREDICTED: similar to
5-methyltetrahydrofolate:homocysteine methyltransferase;
n=2; Strongylocentrotus purpuratus|Rep: PREDICTED:
similar to 5-methyltetrahydrofolate:homocysteine
methyltransferase - Strongylocentrotus purpuratus
Length = 172
Score = 79.0 bits (186), Expect = 1e-13
Identities = 34/53 (64%), Positives = 43/53 (81%)
Frame = +3
Query: 576 IKNWHRTRIQALVEAGVDILAFETIPCQKEAEALVEILKEYPNMKAWLSFSCK 734
+K WHR RIQALV+ VD+LA ETIP EAEAL+ +L+E+P+MKAWL+F CK
Sbjct: 6 LKQWHRPRIQALVDGKVDLLAIETIPSIVEAEALLSVLQEFPSMKAWLTFYCK 58
>UniRef50_Q1DSS3 Cluster: Putative uncharacterized protein; n=1;
Coccidioides immitis|Rep: Putative uncharacterized
protein - Coccidioides immitis
Length = 1785
Score = 74.9 bits (176), Expect = 2e-12
Identities = 53/182 (29%), Positives = 84/182 (46%), Gaps = 18/182 (9%)
Frame = +3
Query: 159 VFVLDGGFSTQLTCHA-GHTADGD-PLWSARFLKTHPQDVINTHLDFLRAGSDIIETNTY 332
+ +LDG T L G T PLWS+ L +HP + H ++ AG+DI+ T TY
Sbjct: 8 ILLLDGAMGTVLEEPPYGFTFSAQTPLWSSHLLLSHPTTLSEIHRSYVDAGADIVLTATY 67
Query: 333 QASVDGFVK----HLNLTVEESYELIKSAVEFARTARDLYLQEC-----QESNLSGRKPL 485
QAS +GF + N+ + + + Y++ N S + P
Sbjct: 68 QASFEGFARTAIVPANVPADHKQDERDGHATYRPMDATRYMRSAIPLAYSSFNFSSKPPR 127
Query: 486 IAGSVGPYGAYLHDTS-EYTGNYADN-TTKETIKNWHRTRIQALVE-----AGVDILAFE 644
+A S+GPYGA + S EYTG Y + + ++ WH R++ +E ++ L FE
Sbjct: 128 VALSLGPYGATMCPVSAEYTGIYPEEMSNTAALEAWHANRLKVYMEDPETWRKIEFLGFE 187
Query: 645 TI 650
T+
Sbjct: 188 TV 189
>UniRef50_A2R696 Cluster: Contig An15c0240, complete genome; n=6;
Pezizomycotina|Rep: Contig An15c0240, complete genome -
Aspergillus niger
Length = 353
Score = 72.9 bits (171), Expect = 7e-12
Identities = 48/152 (31%), Positives = 75/152 (49%), Gaps = 4/152 (2%)
Frame = +3
Query: 159 VFVLDGGFSTQLTCHAGHTADGD--PLWSARFLKTHPQDVINTHLDFLR-AGSDIIETNT 329
+ +LDGG T L H T PLWS+ + + P +++ DF A D++ T T
Sbjct: 6 ILILDGGLGTSLQDHYNITFSSSTTPLWSSHLMISDPSTLLSCQRDFTTTAAVDVLLTAT 65
Query: 330 YQASVDGFVKHLNLTVEESYELIKSAVEFARTARDLYLQECQESNLSGRKPLIAGSVGPY 509
YQ S +GF + + +S + RTA D+ Q Q ++ S +A S+GPY
Sbjct: 66 YQVSPEGFQRTKTPSHPTGIPR-ESIAGYLRTALDVAGQAVQNTSAS-----VALSLGPY 119
Query: 510 GAYLHDTSEYTGNY-ADNTTKETIKNWHRTRI 602
GA + EY+G Y ++ T+E + WH R+
Sbjct: 120 GACMIPGQEYSGKYDGEHDTEEKLWRWHTDRL 151
>UniRef50_Q5KA93 Cluster: Homocysteine S-methyltransferase,
putative; n=1; Filobasidiella neoformans|Rep:
Homocysteine S-methyltransferase, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 381
Score = 71.7 bits (168), Expect = 2e-11
Identities = 48/167 (28%), Positives = 72/167 (43%), Gaps = 3/167 (1%)
Frame = +3
Query: 150 SKTVFVLDGGFSTQLTCHAGHTADGDPLWSARFLKTHPQDVINTHLDFLRAGSDIIETNT 329
S + VLDGG T L + PLW + L+T+P + H +++ G+D++ET T
Sbjct: 2 SSNILVLDGGMGTTLESLGVDISS--PLWGSEALRTNPDVIRKVHEGYVQGGADLVETAT 59
Query: 330 YQASVDGFVKHLNLTVEESYELIKSAVEFARTARDLYLQECQESNL---SGRKPLIAGSV 500
YQ + HL+ EE+ ++ S V+ + +E N G K + S
Sbjct: 60 YQLTPQNLCDHLHCPREEAECILCSGVKLVASCIASCSSRNEEHNTKSKGGNKSKVVLSF 119
Query: 501 GPYGAYLHDTSEYTGNYADNTTKETIKNWHRTRIQALVEAGVDILAF 641
GPYG+ L EY G Y T N EA + LA+
Sbjct: 120 GPYGSTLQPGQEYGGIYPPPFGPSTSTNAFPPDSNDEEEAAIQALAY 166
>UniRef50_A4R5G4 Cluster: Putative uncharacterized protein; n=1;
Magnaporthe grisea|Rep: Putative uncharacterized protein
- Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 374
Score = 70.1 bits (164), Expect = 5e-11
Identities = 59/195 (30%), Positives = 88/195 (45%), Gaps = 24/195 (12%)
Frame = +3
Query: 165 VLDGGFSTQLTCHAGHT-ADGDPLWSARFLKTHPQDVINTHLDFLRAGSDIIETNTYQAS 341
+LDGG T L G PLWS+ L + + + +F AG+D++ T TYQ S
Sbjct: 6 ILDGGLGTTLEDRFGVVFTHAKPLWSSDLLVSDQETLQACQREFAAAGADVLLTATYQVS 65
Query: 342 VDGFVK-----HLNLTVEESYEL--IKSAVEFARTARDLYLQEC--------QESNLSGR 476
V+ F + H + S L ++ AVE A A E++
Sbjct: 66 VEAFARTKTPEHPDGIAPSSAMLPYLRGAVEIAEKAAAAAAAAAAAAAAAPRNETSAPSP 125
Query: 477 KPL-IAGSVGPYGAYLHDTSEYTGNY-ADNTTKETIKNWHRTRIQALVEAGVDI------ 632
+P +A + GPYGA + EYTG Y A ++T + + WH R+ AG D+
Sbjct: 126 QPAELALACGPYGAAMTPGQEYTGAYDAAHSTPDALSRWHLDRLALYAAAGEDVPGRCAY 185
Query: 633 LAFETIPCQKEAEAL 677
+AFET+P E A+
Sbjct: 186 VAFETVPNLAEVWAV 200
>UniRef50_A7TSR2 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 323
Score = 68.5 bits (160), Expect = 2e-10
Identities = 60/203 (29%), Positives = 95/203 (46%), Gaps = 13/203 (6%)
Frame = +3
Query: 159 VFVLDGGFSTQLTCHAGHTADGDPLWSA-RFLK---------THPQDVIN-THLDFLRAG 305
V V DGG T L + + PLWS FLK T +++I + D++ +G
Sbjct: 16 VLVSDGGLGTLLESRGINVSS--PLWSTVPFLKDDFWDSETKTSDRNIIEGIYRDYITSG 73
Query: 306 SDIIETNTYQASVDGFVKHLNLTVEESY-ELIKSAVEFARTARDLYLQECQESNLSGRKP 482
S I+ T TYQ S H + E Y +LI++ F R+A G
Sbjct: 74 SRILSTITYQTSFALISTHTEVKTIEGYKQLIRNITSFCRSA-------------IGEDN 120
Query: 483 LIAGSVGPYGAYLHDTSEYTGNYADNTTKETIKNWHRTRIQALVEAG-VDILAFETIPCQ 659
+ GS+GP+GA L +EYTGNY D+ + + + +++ +DI+ FET+P +
Sbjct: 121 YLIGSIGPFGARLG--AEYTGNYGDSPSNINYLEYFKPQLEEFNNNDDIDIIGFETVPNK 178
Query: 660 KEAEALVEILKEYPNMKAWLSFS 728
E EA++ K + ++S S
Sbjct: 179 YELEAILSWDKSVISKPYYVSLS 201
>UniRef50_Q753B4 Cluster: AFR410Wp; n=1; Eremothecium gossypii|Rep:
AFR410Wp - Ashbya gossypii (Yeast) (Eremothecium
gossypii)
Length = 370
Score = 67.7 bits (158), Expect = 3e-10
Identities = 59/187 (31%), Positives = 87/187 (46%), Gaps = 6/187 (3%)
Frame = +3
Query: 141 EVSSKTVFVLDGGFSTQLTCHAGHTADGDPLWS-ARFLKTHPQ--DVIN-THLDFLRAGS 308
E + V V+DGG +L PLWS A FL+ D I + +F AGS
Sbjct: 53 EFLERNVLVMDGGMGVELERRGMDVKS--PLWSTAPFLRGDRAALDTIRGLYREFRAAGS 110
Query: 309 DIIETNTYQASVDGFVKHL-NLTVEESYELIKSAVEFARTARDLYLQECQESNLSGRKPL 485
I T TYQAS VK+ +++ YE +F D +EC + +
Sbjct: 111 RGISTLTYQASFHSMVKYSGSVSSRADYE------KFLEQVVDFTYRECVDP----ARDY 160
Query: 486 IAGSVGPYGAYLHDTSEYTGNYADNTTKETIKNWHRTRIQAL-VEAGVDILAFETIPCQK 662
I GSVGPY A+L + +EYTG+Y T N+ ++ + +D +AFET+P
Sbjct: 161 IIGSVGPYAAFLCNGAEYTGDYGFETI--NFFNYFEPQVSKFATDPRIDAIAFETVPNVV 218
Query: 663 EAEALVE 683
E A+++
Sbjct: 219 ELMAMLQ 225
>UniRef50_A4B5J7 Cluster: Homocysteine S-methyltransferase family
protein; n=1; Alteromonas macleodii 'Deep ecotype'|Rep:
Homocysteine S-methyltransferase family protein -
Alteromonas macleodii 'Deep ecotype'
Length = 305
Score = 65.7 bits (153), Expect = 1e-09
Identities = 60/193 (31%), Positives = 92/193 (47%), Gaps = 1/193 (0%)
Frame = +3
Query: 153 KTVFVLDGGFSTQLTCHAGHTADGDPLWSARFLKTHPQDVINTHLDFLRAGSDIIETNTY 332
K + +LDGG +L P WSA L P+ V + H FL AG+ +I TNTY
Sbjct: 6 KAIQILDGGMGRELKKIGAPFRQ--PEWSALALMQSPELVSDVHTHFLNAGATVITTNTY 63
Query: 333 QASVDGFVKHLNLTVEESYELIKSAVEFARTARDLYLQECQESNLSGRKPLIAGSVGP-Y 509
A V + E++++L ++A + AR A + Q+ QE NLS +AG + P +
Sbjct: 64 -ALVPFHIGEQTFN-EQAFKLAETAAKLARDAVNAQ-QDKQEGNLS-----VAGCIPPAF 115
Query: 510 GAYLHDTSEYTGNYADNTTKETIKNWHRTRIQALVEAGVDILAFETIPCQKEAEALVEIL 689
G+Y D + + E + I+A +D+ ET +EAEA+V ++
Sbjct: 116 GSYRPDL------FDASRVSEIL----MPLIEAQAPY-IDVWLIETASSIEEAEAVVSLI 164
Query: 690 KEYPNMKAWLSFS 728
K + WLSFS
Sbjct: 165 KTLSSRPIWLSFS 177
>UniRef50_UPI0001555A4D Cluster: PREDICTED: similar to RB-associated
KRAB repressor, partial; n=1; Ornithorhynchus
anatinus|Rep: PREDICTED: similar to RB-associated KRAB
repressor, partial - Ornithorhynchus anatinus
Length = 395
Score = 64.5 bits (150), Expect = 3e-09
Identities = 52/167 (31%), Positives = 81/167 (48%), Gaps = 4/167 (2%)
Frame = +3
Query: 207 GHTADGDPLWSARFLKTHPQDVINTHLDFLRAGSDIIETNTYQ----ASVDGFVKHLNLT 374
G + GDP +K NTH D+L AG+DIIETNT+ A D ++HL
Sbjct: 79 GRSLPGDPAPPTEEMKYDXXXXNNTH-DYLLAGADIIETNTFSGTRVAQADYGLEHL--- 134
Query: 375 VEESYELIKSAVEFARTARDLYLQECQESNLSGRKPLIAGSVGPYGAYLHDTSEYTGNYA 554
+YEL +++ E AR A D + +G K +AG++GP L +
Sbjct: 135 ---AYELNRTSAEVARRAAD------DVAAQTGTKRFVAGALGPTNKTLSVSPSVERPDF 185
Query: 555 DNTTKETIKNWHRTRIQALVEAGVDILAFETIPCQKEAEALVEILKE 695
N T + + +R + + L++ GVDI+ ET+ A+A + L+E
Sbjct: 186 RNITFDELAEAYREQARGLLDGGVDIVLVETVFDTANAKAALFALQE 232
>UniRef50_Q966F6 Cluster: Putative uncharacterized protein T13G4.4;
n=2; Caenorhabditis|Rep: Putative uncharacterized
protein T13G4.4 - Caenorhabditis elegans
Length = 334
Score = 62.9 bits (146), Expect = 8e-09
Identities = 63/221 (28%), Positives = 107/221 (48%), Gaps = 10/221 (4%)
Frame = +3
Query: 102 TINLFFYE--IMSNFEV--SSKTVFVLDGGFSTQLTC--HAGHTADGDPLWSARFLKTHP 263
T ++ F E I+ N ++ S + V +LDG S+QL + + + P WS F
Sbjct: 43 TFSVLFIELCILINLDLFESFRMVRLLDGSMSSQLLRFGYDCNQQENKPHWS--FPANAD 100
Query: 264 QDVI-NTHLDFLRAGSDIIETNTYQASVDGFVKHLNLTVEESYELIKSAVEFARTARDLY 440
+++ N + FL +I +NTY F L+ T+ E+ E K + + + +
Sbjct: 101 MELMENVYKSFLDLEVKVITSNTYH-----FGSTLDKTIPENAE--KREL-YEKYFEETC 152
Query: 441 LQECQESNLSGRKPLIA-GSVGPYGAYLHDTSEYTGNYADNT-TKETIKNWHRTRIQALV 614
L+ C + +G + A GSVG HD SEYTG Y D + K+T ++ + +
Sbjct: 153 LKLCHLT--TGSSDVEAWGSVGTLATMYHDLSEYTGAYMDQSEAKKTAYDYFKIILTLFH 210
Query: 615 E-AGVDILAFETIPCQKEAEALVEILKEYPNMKAWLSFSCK 734
+ + L FETIP E +++L+E+P +A +SF+ K
Sbjct: 211 NRSSIRKLIFETIPSADEGSVALDVLQEFPEFEAVISFTFK 251
>UniRef50_P74718 Cluster: Slr1189 protein; n=1; Synechocystis sp.
PCC 6803|Rep: Slr1189 protein - Synechocystis sp.
(strain PCC 6803)
Length = 351
Score = 61.7 bits (143), Expect = 2e-08
Identities = 60/208 (28%), Positives = 95/208 (45%), Gaps = 8/208 (3%)
Frame = +3
Query: 129 MSNFEVSSKTVFVLDGGFSTQ--------LTCHAGHTADGDPLWSARFLKTHPQDVINTH 284
M+N + +F+LDGG T+ L A HT DPL LK + ++
Sbjct: 39 MTNLPHQCEQIFLLDGGLETEMIFNRGFDLPAFAAHTLLSDPL-GREALKNYFHGFLDLA 97
Query: 285 LDFLRAGSDIIETNTYQASVDGFVKHLNLTVEESYELIKSAVEFARTARDLYLQECQESN 464
+ + +I+ T++A F + L +++EE + AVEFAR + Y+ E Q
Sbjct: 98 KE--KQFGFLIDAPTWRAQ-PFFAEELGVSLEEIRQANFRAVEFARALKQAYVNEIQPL- 153
Query: 465 LSGRKPLIAGSVGPYGAYLHDTSEYTGNYADNTTKETIKNWHRTRIQALVEAGVDILAFE 644
LI G +GP G Y G + N E + +HR +I L EAGVD+L
Sbjct: 154 ------LINGLIGPCG------DAYGGEHFSNA--EAAQVYHRQQISWLAEAGVDLLGAF 199
Query: 645 TIPCQKEAEALVEILKEYPNMKAWLSFS 728
T+ EA +V +E+ ++ +SF+
Sbjct: 200 TLTSVNEAIGIVRASQEF-SLPVSISFT 226
>UniRef50_Q98KX0 Cluster: Mlr1281 protein; n=4; Proteobacteria|Rep:
Mlr1281 protein - Rhizobium loti (Mesorhizobium loti)
Length = 301
Score = 60.1 bits (139), Expect = 6e-08
Identities = 59/194 (30%), Positives = 90/194 (46%), Gaps = 2/194 (1%)
Frame = +3
Query: 153 KTVFVLDGGFSTQLTCHAGHTADGDPLWSARFLKTHPQDVINTHLDFLRAGSDIIETNTY 332
K V + DGG +L + ++ PLWSAR L P V + H +F+RAG+ +I NTY
Sbjct: 2 KNVILTDGGMGQELVRRS--KSEPTPLWSARVLIDEPDLVRDLHAEFIRAGARVITINTY 59
Query: 333 QASVDGFVKHLNLTVEESYE-LIKSAVEFARTARDLYLQECQESNLSGRKPLIAGSVGP- 506
A+ + + E+ ++ L K +E AR Q C E+ + IAG + P
Sbjct: 60 SATPERLARE---GAEDLFKPLQKRGIELAR-------QACDEAG----EAAIAGCLSPL 105
Query: 507 YGAYLHDTSEYTGNYADNTTKETIKNWHRTRIQALVEAGVDILAFETIPCQKEAEALVEI 686
+G+Y T +Y +ET+ + RI A GVD+ ET+ EA A V
Sbjct: 106 FGSY---APALTISY-----QETLDIYR--RIVAEQADGVDLFLCETMASSDEARAAVTA 155
Query: 687 LKEYPNMKAWLSFS 728
E W+S++
Sbjct: 156 ASE-SGKPVWVSWT 168
>UniRef50_P87138 Cluster: Uncharacterized protein C57A7.07c; n=1;
Schizosaccharomyces pombe|Rep: Uncharacterized protein
C57A7.07c - Schizosaccharomyces pombe (Fission yeast)
Length = 308
Score = 59.3 bits (137), Expect = 1e-07
Identities = 50/199 (25%), Positives = 92/199 (46%), Gaps = 8/199 (4%)
Frame = +3
Query: 159 VFVLDGGFSTQLTCHAGHTADGDPLWSARFLKTHPQDVINTHLDFLRAGSDIIETNTYQA 338
+ +LDGG ST + + LW++ L +P+ V+ H +FL+ DII T TYQ
Sbjct: 1 MLMLDGG-STAILPKLPESISESRLWTSEALVRYPEIVVKHHEEFLKV-CDIISTFTYQL 58
Query: 339 SVDGFVKHLNLTVEESYELIKSAVEFARTARDLYLQECQESNLSGRKPLIAGSVGPYGAY 518
+ +E E + +A + + L +L IA +G + A
Sbjct: 59 DASIY--------DEKVEGVPLKQVYANS---IGLPVYAREHLGLPNKYIALCLGSHAAT 107
Query: 519 LHDTSEYTGNYADNTTKETIKNWHRTRIQALVEAG------VDILAFETIPCQKEAEALV 680
+ EY Y T E + N+H+ RI+A+ + +D +AFE++P EAE +
Sbjct: 108 IPGCMEYKMIYDKPTDFEMLYNFHKNRIEAIQASNPKAFEKIDFIAFESLPHVTEAEVVC 167
Query: 681 EILKEYP--NMKAWLSFSC 731
+++++ + + W++ +C
Sbjct: 168 QLIQDMKGWSKRCWITCTC 186
>UniRef50_Q0LM71 Cluster: Methylenetetrahydrofolate reductase; n=1;
Herpetosiphon aurantiacus ATCC 23779|Rep:
Methylenetetrahydrofolate reductase - Herpetosiphon
aurantiacus ATCC 23779
Length = 617
Score = 57.2 bits (132), Expect = 4e-07
Identities = 56/185 (30%), Positives = 79/185 (42%)
Frame = +3
Query: 141 EVSSKTVFVLDGGFSTQLTCHAGHTADGDPLWSARFLKTHPQDVINTHLDFLRAGSDIIE 320
E + + DG TQL G D D + A L T P V H ++ AG+DIIE
Sbjct: 7 EQLGQRALLCDGAMGTQLY---GRGIDFDECFDALNL-TQPDVVREIHQSYIEAGADIIE 62
Query: 321 TNTYQASVDGFVKHLNLTVEESYELIKSAVEFARTARDLYLQECQESNLSGRKPLIAGSV 500
TNTY A + F ++ ++ ++ AR AR+ ++G LIAG+V
Sbjct: 63 TNTYGA--NRFKLEPFGLADKVRQINHRGMKLAREARE----------IAGTNTLIAGAV 110
Query: 501 GPYGAYLHDTSEYTGNYADNTTKETIKNWHRTRIQALVEAGVDILAFETIPCQKEAEALV 680
GP G L T A E +I L+E G D+L FET +E V
Sbjct: 111 GPLGVLLQPYGPLTEQAAHEAFAE--------QIGTLLEQGADLLMFETFSDLREMLIAV 162
Query: 681 EILKE 695
+ K+
Sbjct: 163 KAAKQ 167
>UniRef50_Q8R927 Cluster: Methionine synthase I, cobalamin-binding
domain; n=14; Clostridia|Rep: Methionine synthase I,
cobalamin-binding domain - Thermoanaerobacter
tengcongensis
Length = 803
Score = 55.2 bits (127), Expect = 2e-06
Identities = 62/192 (32%), Positives = 87/192 (45%), Gaps = 1/192 (0%)
Frame = +3
Query: 138 FEVSSKTVFVLDGGFSTQLTCHAGHTADGDPLWSARFLKTHPQDVINTHLDFLRAGSDII 317
F+ V V DG TQL G A P + LK P+ V + H ++ AG+++I
Sbjct: 5 FKECENRVVVFDGAMGTQLQ-ERGLKAGECPEYIN--LKM-PEVVFDIHKAYIEAGAEVI 60
Query: 318 ETNTYQASVDGFVKH-LNLTVEESYELIKSAVEFARTARDLYLQECQESNLSGRKPLIAG 494
ETNT+ A+ K+ L VE E++ VE AR A +G +P +A
Sbjct: 61 ETNTFGANRIKLAKYGLEDKVE---EIVTKGVEIARKA-------------AGDRP-VAL 103
Query: 495 SVGPYGAYLHDTSEYTGNYADNTTKETIKNWHRTRIQALVEAGVDILAFETIPCQKEAEA 674
SVGP G L + T + A KE + A +AG DI+ ET+ EA+A
Sbjct: 104 SVGPTGELLAPFGDMTFDEAYEVFKEV--------VVAAEKAGADIVIIETMSDMLEAKA 155
Query: 675 LVEILKEYPNMK 710
+ KE NMK
Sbjct: 156 AILAAKENTNMK 167
>UniRef50_Q1IQK2 Cluster: 5-methyltetrahydrofolate--homocysteine
S-methyltransferase; n=1; Acidobacteria bacterium
Ellin345|Rep: 5-methyltetrahydrofolate--homocysteine
S-methyltransferase - Acidobacteria bacterium (strain
Ellin345)
Length = 407
Score = 55.2 bits (127), Expect = 2e-06
Identities = 47/166 (28%), Positives = 79/166 (47%), Gaps = 16/166 (9%)
Frame = +3
Query: 246 FLKTHPQDVINTHLDFLRAGSDIIETNTYQAS--------VDGFVKHLNLTVEESYELI- 398
F T PQ + + H FL AG+DIIETNT+ A+ VD +H + Y+ I
Sbjct: 95 FSLTQPQMIGDIHRRFLEAGADIIETNTFGATSIVQSEFFVDDPREHGGRKDADFYQKII 154
Query: 399 --KSAVEFARTARDLYLQECQE-----SNLSGRKPLIAGSVGPYGAYLHDTSEYTGNYAD 557
+ + A + Q+C+E +N + R +AG++GP L ++ +
Sbjct: 155 DDQFLGDLAWEINETSAQQCREWADRVANATSRPRFVAGALGPLTVSLSNSPDADDPGFR 214
Query: 558 NTTKETIKNWHRTRIQALVEAGVDILAFETIPCQKEAEALVEILKE 695
T + +K + +++AL+ GVD L ETI A+A + ++E
Sbjct: 215 VVTFDQVKIAYIQQVRALIAGGVDFLLVETIFDSLNAKAALVAIRE 260
>UniRef50_Q08985 Cluster: Homocysteine S-methyltransferase 2; n=9;
Saccharomycetaceae|Rep: Homocysteine S-methyltransferase
2 - Saccharomyces cerevisiae (Baker's yeast)
Length = 325
Score = 54.8 bits (126), Expect = 2e-06
Identities = 52/188 (27%), Positives = 85/188 (45%), Gaps = 12/188 (6%)
Frame = +3
Query: 153 KTVFVLDGGFSTQLTCHAGHTADGDPLWSA-RFLKTH---PQDVINTHL------DFLRA 302
K V VLDGG T+L A+ P+WS F+ + N + DFL A
Sbjct: 15 KKVLVLDGGQGTELENRGIKVAN--PVWSTIPFISESFWSDESSANRKIVKEMFNDFLNA 72
Query: 303 GSDIIETNTYQASVDGFVKHLNL-TVEESYELIKSAVEFARTARDLYLQECQESNLSGRK 479
G++I+ T TYQ S ++ + T+ E L+ V+F+R N G
Sbjct: 73 GAEILMTTTYQTSYKSVSENTPIRTLSEYNNLLNRIVDFSR-------------NCIGED 119
Query: 480 PLIAGSVGPYGAYLHDTSEYTGNYADNTTKETIKNWHRTRIQALVEAG-VDILAFETIPC 656
+ G +GP+GA H E+TG+Y + + +++ + +D++ FETIP
Sbjct: 120 KYLIGCIGPWGA--HICREFTGDYGAEPENIDFYQYFKPQLENFNKNDKLDLIGFETIPN 177
Query: 657 QKEAEALV 680
E +A++
Sbjct: 178 IHELKAIL 185
>UniRef50_A4XIN4 Cluster: Homocysteine S-methyltransferase; n=1;
Caldicellulosiruptor saccharolyticus DSM 8903|Rep:
Homocysteine S-methyltransferase - Caldicellulosiruptor
saccharolyticus (strain ATCC 43494 / DSM 8903)
Length = 411
Score = 54.0 bits (124), Expect = 4e-06
Identities = 52/175 (29%), Positives = 79/175 (45%), Gaps = 1/175 (0%)
Frame = +3
Query: 153 KTVFVLDGGFSTQLTCHAGHTADGDPLWSARFLKTHPQDVINTHLDFLRAGSDIIETNTY 332
K V V DG TQL + + LWS T P+ + H D+ AGSD +ETNT+
Sbjct: 8 KKVLVFDGAMGTQLIQNGLKENECPDLWSV----TRPEVIAKIHRDYFEAGSDCVETNTF 63
Query: 333 QASVDGFVKHLNLTVEESYELI-KSAVEFARTARDLYLQECQESNLSGRKPLIAGSVGPY 509
A+ + K+ +E E I K+A+ A+ Y G + SVGP
Sbjct: 64 GANREKLKKY---GLENEVEKINKAAILLAKDVAKEY---------GG---YVGLSVGPT 108
Query: 510 GAYLHDTSEYTGNYADNTTKETIKNWHRTRIQALVEAGVDILAFETIPCQKEAEA 674
G + + + + A++ E +I A +EAG D ++ ET+ KEA+A
Sbjct: 109 GRLMRPSGDLDFDEAESVFYE--------QILAGIEAGADFISIETMSDIKEAKA 155
>UniRef50_A1SWN6 Cluster: Homocysteine S-methyltransferase; n=2;
Gammaproteobacteria|Rep: Homocysteine
S-methyltransferase - Psychromonas ingrahamii (strain
37)
Length = 310
Score = 54.0 bits (124), Expect = 4e-06
Identities = 59/191 (30%), Positives = 84/191 (43%), Gaps = 1/191 (0%)
Frame = +3
Query: 165 VLDGGFSTQLTCHAGHTADGDPLWSARFLKTHPQDVINTHLDFLRAGSDIIETNTYQASV 344
+LDGG +L G P WSA+ L P + H F+ AG+++I TNTY A V
Sbjct: 18 ILDGGMGRELK-RIGAPFQ-QPEWSAQALIESPHFISEVHKSFIEAGAEVITTNTY-ALV 74
Query: 345 DGFVKHLNLTVEESYELIKSAVEFARTARDLYLQECQESNLSGRKPLIAGSVGP-YGAYL 521
+ E+ +LIK A AR EC + N + L+AG + P G+Y
Sbjct: 75 PFHIGEKRFN-EQGADLIKLAARLAR--------ECVKENSA---VLVAGCIPPVLGSYR 122
Query: 522 HDTSEYTGNYADNTTKETIKNWHRTRIQALVEAGVDILAFETIPCQKEAEALVEILKEYP 701
D ++ A + IKN EA VDI ETI EA A+++
Sbjct: 123 PDL--FSVEKAKPVLELLIKN---------QEADVDIWLAETISSIAEA-AMIKARTVVT 170
Query: 702 NMKAWLSFSCK 734
N W++F+ K
Sbjct: 171 NKPTWIAFTIK 181
>UniRef50_A5UPF4 Cluster: Methionine synthase; n=4;
Chloroflexaceae|Rep: Methionine synthase - Roseiflexus
sp. RS-1
Length = 1254
Score = 53.6 bits (123), Expect = 5e-06
Identities = 49/173 (28%), Positives = 81/173 (46%), Gaps = 4/173 (2%)
Frame = +3
Query: 141 EVSSKTVFVLDGGFSTQLTCHAGHTAD--GDPLWSAR--FLKTHPQDVINTHLDFLRAGS 308
E + V + DG T + AD G+ + AR + T P + H FL AG+
Sbjct: 52 EALRERVLIYDGAMGTSIDTFHLTAADYGGENTFGARDYLVMTRPDVIEQIHTSFLEAGA 111
Query: 309 DIIETNTYQASVDGFVKHLNLTVEESYELIKSAVEFARTARDLYLQECQESNLSGRKPLI 488
D++ET T+Q S ++ L ++++ + +A AR D + E ++ GR +
Sbjct: 112 DVLETCTFQ-STRIRLEEWGL-ADQTHAINVAAARLARRVADAF--EARD----GRPRYV 163
Query: 489 AGSVGPYGAYLHDTSEYTGNYADNTTKETIKNWHRTRIQALVEAGVDILAFET 647
AGS+GP G S + +D T + ++ + AL+E GVD+L ET
Sbjct: 164 AGSMGPTGKL---PSSDDPSLSDITFDQLSDIFYEQAV-ALIEGGVDVLLVET 212
>UniRef50_Q024B4 Cluster: Homocysteine S-methyltransferase; n=1;
Solibacter usitatus Ellin6076|Rep: Homocysteine
S-methyltransferase - Solibacter usitatus (strain
Ellin6076)
Length = 304
Score = 53.2 bits (122), Expect = 6e-06
Identities = 47/175 (26%), Positives = 76/175 (43%)
Frame = +3
Query: 171 DGGFSTQLTCHAGHTADGDPLWSARFLKTHPQDVINTHLDFLRAGSDIIETNTYQASVDG 350
DG TQL + LW+ THP+ V+ + AGSD I TNT+ S
Sbjct: 17 DGAMGTQLMFAGLEQGNCGELWNL----THPERVLGIQRRYAEAGSDCILTNTFGGSRIM 72
Query: 351 FVKHLNLTVEESYELIKSAVEFARTARDLYLQECQESNLSGRKPLIAGSVGPYGAYLHDT 530
+H + + E+ ++AVE AR A GR + G +GP+G +
Sbjct: 73 LNRH--GSSGKVVEINRAAVEIAREA------------FGGRAGYVIGDIGPFGGLMQPY 118
Query: 531 SEYTGNYADNTTKETIKNWHRTRIQALVEAGVDILAFETIPCQKEAEALVEILKE 695
++ T+E +++ + ALV+AG D + ET +E + +E +E
Sbjct: 119 GDF--------TEEDVRSAFGEQAGALVDAGADAIIIETQTSLEELQLGIEAARE 165
>UniRef50_A5TSW8 Cluster: Methionine synthase; n=3; Fusobacterium
nucleatum|Rep: Methionine synthase - Fusobacterium
nucleatum subsp. polymorphum ATCC 10953
Length = 1082
Score = 53.2 bits (122), Expect = 6e-06
Identities = 59/208 (28%), Positives = 95/208 (45%), Gaps = 8/208 (3%)
Frame = +3
Query: 129 MSNFEVSSKT-VFVLDGGFSTQLTCHAGHTADGDPLWSARFL--KTHPQDVINTHLDFLR 299
M FE K + VLDG T L + D + + +T P + H ++
Sbjct: 1 MFEFEKELKERILVLDGAMGTVLQKYELTPEDFNGAKGCYEILNETRPDIIFEVHKKYIE 60
Query: 300 AGSDIIETNTYQASVDGFVKHLNLTVEESYELIKSAVEFARTARDLYLQECQESNLSGRK 479
AG+DIIETN++ + +K +L ++ Y+L K + E AR A ++E SG+K
Sbjct: 61 AGADIIETNSFNCNAIS-LKDYHLE-DKVYDLAKKSAEIARDA----VKE------SGKK 108
Query: 480 PLIAGSVGPYGAYLHDTSEYTGN--YADNTTKETIKNWHRTRIQALVEAGVDILAFETI- 650
+ GS+GP L S G+ Y + + +K + ++ L++ GVD + ETI
Sbjct: 109 VYVFGSIGPTNKSL---SFPVGDVPYKRAVSFDEMKEVIKVQVAGLIDGGVDGILLETIF 165
Query: 651 --PCQKEAEALVEILKEYPNMKAWLSFS 728
K A E + E N+K +S S
Sbjct: 166 DGLTAKAALLATEEVFEEKNVKLPISIS 193
>UniRef50_Q15S12 Cluster: Homocysteine S-methyltransferase; n=1;
Pseudoalteromonas atlantica T6c|Rep: Homocysteine
S-methyltransferase - Pseudoalteromonas atlantica
(strain T6c / BAA-1087)
Length = 304
Score = 52.8 bits (121), Expect = 8e-06
Identities = 52/194 (26%), Positives = 85/194 (43%)
Frame = +3
Query: 147 SSKTVFVLDGGFSTQLTCHAGHTADGDPLWSARFLKTHPQDVINTHLDFLRAGSDIIETN 326
S T+ +LDGG +L + D P+WSA + P+ V + H +F+ +G+ +I N
Sbjct: 8 SKSTITILDGGMGQELLRRSSR--DVTPMWSADIMLNEPELVRDLHREFINSGARVITLN 65
Query: 327 TYQASVDGFVKHLNLTVEESYELIKSAVEFARTARDLYLQECQESNLSGRKPLIAGSVGP 506
TY A+ L E +E + A A + Q ++ +IAGS+ P
Sbjct: 66 TYTATPQ------RLKRENQFEQFVHLHDAAMRAAQEAIALTQRDDV-----MIAGSLPP 114
Query: 507 YGAYLHDTSEYTGNYADNTTKETIKNWHRTRIQALVEAGVDILAFETIPCQKEAEALVEI 686
A H E + ++ D+ +R ++ AL G DI ET+ EA+A
Sbjct: 115 LVASYH--PEVSLSFEDSLVS------YR-QLVALQSLGSDIFICETMSSICEAQAACTA 165
Query: 687 LKEYPNMKAWLSFS 728
KE W++F+
Sbjct: 166 AKE-SGKPVWVAFT 178
>UniRef50_Q01YW7 Cluster: Methionine synthase; n=2; Bacteria|Rep:
Methionine synthase - Solibacter usitatus (strain
Ellin6076)
Length = 1185
Score = 52.8 bits (121), Expect = 8e-06
Identities = 41/131 (31%), Positives = 60/131 (45%)
Frame = +3
Query: 255 THPQDVINTHLDFLRAGSDIIETNTYQASVDGFVKHLNLTVEESYELIKSAVEFARTARD 434
T P + + H +L AG+DIIETNT+ + N E +YEL +A + AR D
Sbjct: 54 TRPDVIQDIHRQYLEAGADIIETNTFGGTRIALAD--NKLEERAYELNFAAAKLAREVAD 111
Query: 435 LYLQECQESNLSGRKPLIAGSVGPYGAYLHDTSEYTGNYADNTTKETIKNWHRTRIQALV 614
+ + + + +AGS+GP L N +TT IK + + + LV
Sbjct: 112 QF-------STAAKPRFVAGSIGPTNKDL--------NITGSTTFPEIKAAYYEQAKGLV 156
Query: 615 EAGVDILAFET 647
E G D L ET
Sbjct: 157 EGGADYLLIET 167
>UniRef50_Q7VBY3 Cluster: 5-methyltetrahydrofolate--homocysteine
methyltransferase; n=8; Cyanobacteria|Rep:
5-methyltetrahydrofolate--homocysteine methyltransferase
- Prochlorococcus marinus
Length = 1182
Score = 52.4 bits (120), Expect = 1e-05
Identities = 53/184 (28%), Positives = 89/184 (48%), Gaps = 5/184 (2%)
Frame = +3
Query: 123 EIMSNFEVSSKTVFVLDGGFSTQLTCHAGHTAD--GDPLWSA---RFLKTHPQDVINTHL 287
+ S S +V V DG T L TAD G L + T+PQ V N H
Sbjct: 3 DFKSYINSSKSSVLVFDGAMGTSLQS-LNLTADDFGGTLLEGCNENLVLTNPQAVRNVHR 61
Query: 288 DFLRAGSDIIETNTYQASVDGFVKHLNLTVEESYELIKSAVEFARTARDLYLQECQESNL 467
+L G D+IETNT+ A+ ++ NL +++YE+ +E AR A+ + +E +
Sbjct: 62 SYLEVGCDVIETNTFGAT-SIVLEEYNLQ-DKTYEI---NLEAARLAKGI----VKEFST 112
Query: 468 SGRKPLIAGSVGPYGAYLHDTSEYTGNYADNTTKETIKNWHRTRIQALVEAGVDILAFET 647
+ +AGSVGP T++ + + + + + ++ +I+AL++ VD++ ET
Sbjct: 113 DDKPRFVAGSVGP-------TTKLP--TLGHISFDKLSSSYQEQIEALIDGEVDLILLET 163
Query: 648 IPCQ 659
CQ
Sbjct: 164 --CQ 165
>UniRef50_Q93A68 Cluster: Methylenetetrahydrofolate reductase; n=2;
Bacteria|Rep: Methylenetetrahydrofolate reductase -
uncultured bacterium
Length = 612
Score = 52.4 bits (120), Expect = 1e-05
Identities = 54/184 (29%), Positives = 81/184 (44%), Gaps = 5/184 (2%)
Frame = +3
Query: 159 VFVLDGGFSTQLTCHAGHTADGDPLWSARFLKTHPQDVINTHLDFLRAGSDIIETNTYQA 338
+ + DG T L T P A L +P V H ++ AG+ +IETNTY A
Sbjct: 1 MLIADGAIGTMLALRGVPT----PYELANLL--YPDTVRALHREYYEAGARLIETNTYTA 54
Query: 339 S-VDGF-VKHLNLTVEESYELIK---SAVEFARTARDLYLQECQESNLSGRKPLIAGSVG 503
+ V F + +Y L++ S E R ++ +E+ G L+ GSVG
Sbjct: 55 NRVRLFNLPERGSEAPPTYSLLEQFGSPEELVRRINQEAVRLAREA--VGADALVFGSVG 112
Query: 504 PYGAYLHDTSEYTGNYADNTTKETIKNWHRTRIQALVEAGVDILAFETIPCQKEAEALVE 683
P G L E + A+ +E ++QAL+EAGVD L ET +E E +
Sbjct: 113 PVGKPLEPIGETRLDEAEGAFRE--------QMQALLEAGVDGLILETFIDPRELELAIR 164
Query: 684 ILKE 695
+ +E
Sbjct: 165 VARE 168
>UniRef50_Q2LWJ5 Cluster: 5-methyltetrahydrofolate--homocysteine
methyltransferase; n=3; Bacteria|Rep:
5-methyltetrahydrofolate--homocysteine methyltransferase
- Syntrophus aciditrophicus (strain SB)
Length = 813
Score = 51.6 bits (118), Expect = 2e-05
Identities = 50/181 (27%), Positives = 78/181 (43%)
Frame = +3
Query: 153 KTVFVLDGGFSTQLTCHAGHTADGDPLWSARFLKTHPQDVINTHLDFLRAGSDIIETNTY 332
K + VLDG T+L LW HP+ + H + +AGSDI+ T T+
Sbjct: 13 KKILVLDGATGTELQKRGMPGGVCPELWCLE----HPEIIKEIHRSYRQAGSDIVYTCTF 68
Query: 333 QASVDGFVKHLNLTVEESYELIKSAVEFARTARDLYLQECQESNLSGRKPLIAGSVGPYG 512
A+ K E E+ ++ AR A G K L+AG +GP G
Sbjct: 69 GANR---YKLAQYGTREVREINRNLARLARHA-------------VGPKALVAGDIGPTG 112
Query: 513 AYLHDTSEYTGNYADNTTKETIKNWHRTRIQALVEAGVDILAFETIPCQKEAEALVEILK 692
++ + D +E + + + +IQ L+E GVD+ ET+ +EA A + +K
Sbjct: 113 HFVEP-------FGDLPFEEAVSAF-KEQIQGLLEGGVDLFVIETMMDIQEARAALIAVK 164
Query: 693 E 695
E
Sbjct: 165 E 165
>UniRef50_Q99707 Cluster: Methionine synthase; n=268; cellular
organisms|Rep: Methionine synthase - Homo sapiens
(Human)
Length = 1265
Score = 51.6 bits (118), Expect = 2e-05
Identities = 56/199 (28%), Positives = 89/199 (44%), Gaps = 16/199 (8%)
Frame = +3
Query: 144 VSSKTVFVLDGGFSTQLT---CHAGHTADGDPLWSARFLK--------THPQDVINTHLD 290
+ K + VLDGG T + + H + AR LK T P + H +
Sbjct: 25 ILQKRIMVLDGGMGTMIQREKLNEEHFRGQEFKDHARPLKGNNDILSITQPDVIYQIHKE 84
Query: 291 FLRAGSDIIETNTYQ----ASVDGFVKHLNLTVEESYELIKSAVEFAR-TARDLYLQECQ 455
+L AG+DIIETNT+ A D ++HL +Y + + AR A ++ LQ
Sbjct: 85 YLLAGADIIETNTFSSTSIAQADYGLEHL------AYRMNMCSAGVARKAAEEVTLQ--- 135
Query: 456 ESNLSGRKPLIAGSVGPYGAYLHDTSEYTGNYADNTTKETIKNWHRTRIQALVEAGVDIL 635
+G K +AG++GP L + N T + + ++ + + L++ GVDIL
Sbjct: 136 ----TGIKRFVAGALGPTNKTLSVSPSVERPDYRNITFDELVEAYQEQAKGLLDGGVDIL 191
Query: 636 AFETIPCQKEAEALVEILK 692
ETI A+A + L+
Sbjct: 192 LIETIFDTANAKAALFALQ 210
>UniRef50_Q2S678 Cluster: Vitamin B12-dependent methionine synthase
family protein; n=1; Salinibacter ruber DSM 13855|Rep:
Vitamin B12-dependent methionine synthase family protein
- Salinibacter ruber (strain DSM 13855)
Length = 320
Score = 50.8 bits (116), Expect = 3e-05
Identities = 47/172 (27%), Positives = 68/172 (39%), Gaps = 10/172 (5%)
Frame = +3
Query: 165 VLDGGFSTQLTCHAGHTADGDPLWSARFLKTHPQDVINTHLDFLRAGSDIIETNTY---- 332
+LDGG +L G + LWSA L P V H ++LRAG+D+I TNTY
Sbjct: 14 LLDGGLGQELI-RRGMPSTEPSLWSANALTEAPDLVQEVHEEYLRAGADVITTNTYATPP 72
Query: 333 ----QASVDGFVKHLNLTVEESYELIKSAVEFARTARDLYLQECQESNLSGRKPLIAGSV 500
+A +DG + LN E ++AV RD + +P + G
Sbjct: 73 ERLSEAGLDGRAEALNREAGRLAERARAAV-----GRDALIAGSLPPIRGSYRPDLVGEA 127
Query: 501 GPYGAYLHDTSEYTGNYADNTTKETIKNWHRTRIQA--LVEAGVDILAFETI 650
G + + Y + D ET+ R A G+ +L TI
Sbjct: 128 GEIEPQYREQAGYLAPHVDLFLCETMSTPGEARAAARGAASTGLPVLVSYTI 179
>UniRef50_UPI0000E47473 Cluster: PREDICTED: hypothetical protein;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 176
Score = 50.4 bits (115), Expect = 4e-05
Identities = 43/138 (31%), Positives = 63/138 (45%), Gaps = 1/138 (0%)
Frame = +3
Query: 234 WSARFLKTHPQDVINTHLDFLRAGSDIIETNTYQASVDGFVKHLNLTVEESYELIKSAV- 410
W+ +P V H +FLRAG+D+I+T TY A+ D +K N + S ++ +V
Sbjct: 43 WTPEATLQYPDAVKQLHREFLRAGADVIQTFTYCATEDN-LKMKNEHEKNSNDMKSVSVS 101
Query: 411 EFARTARDLYLQECQESNLSGRKPLIAGSVGPYGAYLHDTSEYTGNYADNTTKETIKNWH 590
E A DL + E L+AGSV AY D + KE ++N
Sbjct: 102 EINHRACDLAREVANEGG-----ALVAGSVSNVNAYRKDGA------CHGAGKEFVQNEF 150
Query: 591 RTRIQALVEAGVDILAFE 644
+ + LV+ GVD L E
Sbjct: 151 KKQCDILVKKGVDFLLGE 168
>UniRef50_Q4DI99 Cluster: Homocysteine S-methyltransferase,
putative; n=2; Trypanosoma cruzi|Rep: Homocysteine
S-methyltransferase, putative - Trypanosoma cruzi
Length = 410
Score = 50.4 bits (115), Expect = 4e-05
Identities = 58/211 (27%), Positives = 88/211 (41%), Gaps = 31/211 (14%)
Frame = +3
Query: 159 VFVLDGGFSTQLTCHAGHTADGDPLWSARFLKTHPQDVINTHLDFLRAGSDIIETNTYQA 338
V + DG T L A +WS+ L + V H ++ AG D++ T TYQ
Sbjct: 9 VLIKDGAMGTLLESWDVDYAKAGSMWSSSVLLSEMDLVKRAHRAYIDAGCDVLLTCTYQM 68
Query: 339 SVDGFVKHLNLTVEESYELIKSAVEFAR---------------TARDL---------YLQ 446
+G +T+ EL+ AV+ AR TA++ Y
Sbjct: 69 HEEGCAAS-KVTM---CELVDRAVQAARHTMPQRKQKGLTEESTAKERRTGGIDVFRYAL 124
Query: 447 ECQESNLSGRKPLIAGSVGPYGAYLHDTSEYTGNYADNTTKETIKNWHRTRIQA-LVEAG 623
+ N R L+AGS+GPYG+ L EY G Y+ + + I +H R++A L G
Sbjct: 125 SSIKDNGQERVVLLAGSLGPYGSSLPGGQEYLGEYSIH--EAVINAFHARRLEAFLCNVG 182
Query: 624 ------VDILAFETIPCQKEAEALVEILKEY 698
VD L ET P EA ++ + ++
Sbjct: 183 EKHAFKVDFLLLETFPRLDEALGILSFVNQH 213
>UniRef50_Q30ZI4 Cluster: Vitamin B12-dependent methionine synthase
family protein; n=3; Desulfovibrio|Rep: Vitamin
B12-dependent methionine synthase family protein -
Desulfovibrio desulfuricans (strain G20)
Length = 841
Score = 49.6 bits (113), Expect = 8e-05
Identities = 49/195 (25%), Positives = 87/195 (44%)
Frame = +3
Query: 144 VSSKTVFVLDGGFSTQLTCHAGHTADGDPLWSARFLKTHPQDVINTHLDFLRAGSDIIET 323
+S T+ DG T L G A P F ++P + HLD+ RAG+D++ T
Sbjct: 39 LSDDTLLFFDGAMGTMLQGR-GLPAGMSP---EVFCLSNPAVLQGVHLDYARAGADVLTT 94
Query: 324 NTYQASVDGFVKHLNLTVEESYELIKSAVEFARTARDLYLQECQESNLSGRKPLIAGSVG 503
NT+ + L + E +++ E AR A+ + +GR +AGSVG
Sbjct: 95 NTFGGT--------RLKLPEGMNVVEFNREMARAAK-------AAAGQAGRTVFVAGSVG 139
Query: 504 PYGAYLHDTSEYTGNYADNTTKETIKNWHRTRIQALVEAGVDILAFETIPCQKEAEALVE 683
P G ++ + +++ + + R +I+ LV+ G+D++ ET E A+V
Sbjct: 140 PTGHFVKPLGDL--EFSE------LVDIFREQIRGLVQGGIDLVLAETHFDLAEVRAVVL 191
Query: 684 ILKEYPNMKAWLSFS 728
+ N+ +S +
Sbjct: 192 AARAECNLPVGVSMT 206
>UniRef50_Q2AGF5 Cluster: Dihydropteroate synthase,
DHPS:Homocysteine S- methyltransferase:Methionine
synthase, B12-binding module, cap:Cobalamin B12-binding;
n=1; Halothermothrix orenii H 168|Rep: Dihydropteroate
synthase, DHPS:Homocysteine S-
methyltransferase:Methionine synthase, B12-binding
module, cap:Cobalamin B12-binding - Halothermothrix
orenii H 168
Length = 819
Score = 49.2 bits (112), Expect = 1e-04
Identities = 50/181 (27%), Positives = 77/181 (42%), Gaps = 1/181 (0%)
Frame = +3
Query: 159 VFVLDGGFSTQLTCHAGHTADGDPLWSARFLKTHPQDVINTHLDFLRAGSDIIETNTYQA 338
+ + DG T L + W + P + H +++ AG+ +IETNT+ A
Sbjct: 13 IIIGDGAMGTMLQACGLSSGHAPESWVIK----KPDTIYKIHKEYVAAGAGLIETNTFGA 68
Query: 339 SVDGFVKHLNLTVEESYELIK-SAVEFARTARDLYLQECQESNLSGRKPLIAGSVGPYGA 515
+ +K +L +E+ E I A AR A K +AGSVGP G
Sbjct: 69 NR---LKLKSLGLEDKIEEINVKATGLARKAAG--------------KVFVAGSVGPTGK 111
Query: 516 YLHDTSEYTGNYADNTTKETIKNWHRTRIQALVEAGVDILAFETIPCQKEAEALVEILKE 695
+ + + + A + KE +I LV AGVD++ ET+ KE A V KE
Sbjct: 112 LMEPHGDLSFDRARDVFKE--------QISYLVHAGVDVVIIETMSDLKELRAAVVAAKE 163
Query: 696 Y 698
+
Sbjct: 164 F 164
>UniRef50_A7SKT1 Cluster: Predicted protein; n=4; Eumetazoa|Rep:
Predicted protein - Nematostella vectensis
Length = 1178
Score = 49.2 bits (112), Expect = 1e-04
Identities = 35/133 (26%), Positives = 67/133 (50%), Gaps = 1/133 (0%)
Frame = +3
Query: 255 THPQDVINTHLDFLRAGSDIIETNTYQASVDGFVKHLNLTVEE-SYELIKSAVEFARTAR 431
T P +++ H +L AG+D +ETNT+ + + + +E+ +Y L +++ E A+ A
Sbjct: 43 TKPDAILDIHKGYLEAGADFVETNTFSGTK---IAQADYGLEDAAYRLNRASAEVAKRA- 98
Query: 432 DLYLQECQESNLSGRKPLIAGSVGPYGAYLHDTSEYTGNYADNTTKETIKNWHRTRIQAL 611
E S +G + +AG++GP L + N T + + + + + + L
Sbjct: 99 ---AYEVTAS--TGVEKFVAGAMGPTNRTLSISPTVECPGFRNVTFDELVDAYTEQARGL 153
Query: 612 VEAGVDILAFETI 650
++ GVD+L ETI
Sbjct: 154 LDGGVDVLLVETI 166
>UniRef50_A4XIN5 Cluster: Methylenetetrahydrofolate reductase; n=1;
Caldicellulosiruptor saccharolyticus DSM 8903|Rep:
Methylenetetrahydrofolate reductase -
Caldicellulosiruptor saccharolyticus (strain ATCC 43494
/ DSM 8903)
Length = 604
Score = 48.8 bits (111), Expect = 1e-04
Identities = 54/186 (29%), Positives = 84/186 (45%), Gaps = 2/186 (1%)
Frame = +3
Query: 144 VSSKTVFVLDGGFSTQLTCHAGHTADGDPLWSARFLKTHPQDVINTHLDFLRAGSDIIET 323
+S + + + DG T+L + G+ D W+ ++P V + H D++ AGS IET
Sbjct: 8 LSQQDIVLFDGAMGTELL-NRGYNKDFPLEWANI---SNPDLVKSIHSDYILAGSQCIET 63
Query: 324 NTYQASVDGFVKHLNL-TVEESYELI-KSAVEFARTARDLYLQECQESNLSGRKPLIAGS 497
NT+ A+ LNL E E I ++AV+ A+ ++G+ + GS
Sbjct: 64 NTFGAN----ECRLNLYGFEGQVEKINRNAVKIAK-------------EVAGQTAYVIGS 106
Query: 498 VGPYGAYLHDTSEYTGNYADNTTKETIKNWHRTRIQALVEAGVDILAFETIPCQKEAEAL 677
VGP G + E D KE K ++ L++ GVD + FET E
Sbjct: 107 VGPLGKPVGSGFEID----DKRAKEVYKK----QLYFLLDEGVDAILFETAASTHEVLIA 158
Query: 678 VEILKE 695
+E LKE
Sbjct: 159 IEALKE 164
>UniRef50_A7RIN6 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 434
Score = 48.8 bits (111), Expect = 1e-04
Identities = 56/179 (31%), Positives = 86/179 (48%)
Frame = +3
Query: 159 VFVLDGGFSTQLTCHAGHTADGDPLWSARFLKTHPQDVINTHLDFLRAGSDIIETNTYQA 338
V + DGG S L + G +W+ + HP+ V H +FLRAG+D+I+ T+ A
Sbjct: 22 VIIGDGGMSHALEKRC-YVKIG--VWTPECVVEHPEAVRQLHSEFLRAGADVIQAFTF-A 77
Query: 339 SVDGFVKHLNLTVEESYELIKSAVEFARTARDLYLQECQESNLSGRKPLIAGSVGPYGAY 518
D K L ++ SY+ E +R L +E + G L +GS+ G
Sbjct: 78 MQD---KPL-VSAGYSYKWD----EISRAGSIL----AKEVSDKGEFALSSGSLCETG-- 123
Query: 519 LHDTSEYTGNYADNTTKETIKNWHRTRIQALVEAGVDILAFETIPCQKEAEALVEILKE 695
S + A TKE IK R +++ V+ G+D+L E I +EAE +VE++KE
Sbjct: 124 ----SLFIKGLA---TKEEIKQRFRDQVKIFVDTGMDLLIAEYISHVQEAEWMVEVMKE 175
>UniRef50_Q4FMM0 Cluster: Homocysteine S-methyltransferase; n=3;
Bacteria|Rep: Homocysteine S-methyltransferase -
Pelagibacter ubique
Length = 302
Score = 48.4 bits (110), Expect = 2e-04
Identities = 51/186 (27%), Positives = 91/186 (48%), Gaps = 4/186 (2%)
Frame = +3
Query: 153 KTVFVLDGGFSTQLTCHAGHTADGDPLWSARFL--KTHPQDVINTHLDFLRAGSDIIETN 326
KT +LDGG +L G +G LWSA + + + Q +++THLDF++AG+++I T
Sbjct: 7 KTTRILDGGMGQELLAR-GMKPNGT-LWSANAVLKEEYHQLLLDTHLDFIKAGAEVIVTA 64
Query: 327 TYQASVDGFVKHLNLTVEESYE-LIKSAVEFARTARDLYLQECQESNLSGRKPLIAGSVG 503
T+ ++ + +E+ +E L K A E A+ A++ Q N+ LIAG +
Sbjct: 65 TFTTR---RIRLRDNKIEDKFEYLNKKAGEIAQKAKE------QHPNV-----LIAGGLP 110
Query: 504 P-YGAYLHDTSEYTGNYADNTTKETIKNWHRTRIQALVEAGVDILAFETIPCQKEAEALV 680
P Y Y DT D+ K+ + + L++ +D + + KE + +
Sbjct: 111 PQYLTYEEDTR------PDDEIKQNFYDQAK-----LLDPYIDFFYLDVLSSVKEFKLAI 159
Query: 681 EILKEY 698
E ++E+
Sbjct: 160 EAIEEF 165
>UniRef50_A7AL74 Cluster: Putative uncharacterized protein; n=1;
Parabacteroides merdae ATCC 43184|Rep: Putative
uncharacterized protein - Parabacteroides merdae ATCC
43184
Length = 1231
Score = 48.4 bits (110), Expect = 2e-04
Identities = 41/151 (27%), Positives = 70/151 (46%), Gaps = 4/151 (2%)
Frame = +3
Query: 255 THPQDVINTHLDFLRAGSDIIETNTYQASVDGFVKHLNLTVEESYELIKSAVEFARTARD 434
T P + + H +L AG+DI TNT+ A+ + + L +A + AR D
Sbjct: 57 TRPDVIKSIHRQYLDAGADIFATNTFNANAISMEDYGMQGQVRNINL--AAGKLAREVAD 114
Query: 435 LYLQECQESNLSGRKPLIAGSVGPYGAYLHDTSEYTGNYADNTTKETIKNWHRTRIQALV 614
+++E + R +AGSVGP + + + T + + ++ ++ ALV
Sbjct: 115 GFMKEHPD-----RTIFVAGSVGPTNKTASMSPDVSDPAYRAVTYLDLYSAYKEQVDALV 169
Query: 615 EAGVDILAFE----TIPCQKEAEALVEILKE 695
+ GVDI+ FE T+ + EA +LKE
Sbjct: 170 DGGVDIVLFETTFDTLNVKAGLEAAEAVLKE 200
>UniRef50_A6G2A6 Cluster: Homocysteine S-methyltransferase,
putative; n=1; Plesiocystis pacifica SIR-1|Rep:
Homocysteine S-methyltransferase, putative -
Plesiocystis pacifica SIR-1
Length = 322
Score = 48.4 bits (110), Expect = 2e-04
Identities = 53/186 (28%), Positives = 81/186 (43%)
Frame = +3
Query: 165 VLDGGFSTQLTCHAGHTADGDPLWSARFLKTHPQDVINTHLDFLRAGSDIIETNTYQASV 344
+LDG +T+L G + PL++AR L P ++ H D+ AG+ ++ TN++
Sbjct: 9 LLDGALATELR-RRGFELEA-PLFAARALLEAPDLLVEIHRDYALAGAQVLSTNSFGLHA 66
Query: 345 DGFVKHLNLTVEESYELIKSAVEFARTARDLYLQECQESNLSGRKPLIAGSVGPYGAYLH 524
+ E EL +VE AR L Q E S R +A SV P
Sbjct: 67 ATLAR--AGMAERQAELAARSVELTFLARQLVRQSGSE-RTSFR---VAASVPP-----P 115
Query: 525 DTSEYTGNYADNTTKETIKNWHRTRIQALVEAGVDILAFETIPCQKEAEALVEILKEYPN 704
S G+ A T+ + R+ ALV+AG D++ FET + A +E+
Sbjct: 116 PPSPSEGD-APELTRAAL----RSLASALVDAGADLVLFETFAKPEHIRAALEVAGAL-E 169
Query: 705 MKAWLS 722
+ WLS
Sbjct: 170 VPVWLS 175
>UniRef50_A5KL27 Cluster: Putative uncharacterized protein; n=4;
Bacteria|Rep: Putative uncharacterized protein -
Ruminococcus torques ATCC 27756
Length = 826
Score = 48.4 bits (110), Expect = 2e-04
Identities = 53/182 (29%), Positives = 77/182 (42%), Gaps = 1/182 (0%)
Frame = +3
Query: 153 KTVFVLDGGFSTQLTCHAGHTADGDPLWSARFLKTHPQDVINTHLDFLRAGSDIIETNTY 332
K + DGG T L + W+ TH +++ H ++ AGSDII TNT+
Sbjct: 8 KDLLFFDGGMGTLLQEKGLAPGELPETWNL----THSEEIYKIHRQYIEAGSDIILTNTF 63
Query: 333 QASVDGFVKHLNLTVEESYELIKSAVEFARTA-RDLYLQECQESNLSGRKPLIAGSVGPY 509
A+ F + ++E E+IK+AV + A R+ LQ E RK A VGP
Sbjct: 64 GANALKFHDD-SCSLE---EIIKAAVSHVKKAEREALLQTGDE-----RKIYTALDVGPT 114
Query: 510 GAYLHDTSEYTGNYADNTTKETIKNWHRTRIQALVEAGVDILAFETIPCQKEAEALVEIL 689
G L + A KE + +AG D++ ET+ E +A V
Sbjct: 115 GKLLKPMGDLEFETAYEAFKEVVILGE--------QAGADLIHIETMSDTYELKAAVLAA 166
Query: 690 KE 695
KE
Sbjct: 167 KE 168
>UniRef50_Q4GZ92 Cluster: Homocysteine S-methyltransferase,
putative; n=1; Trypanosoma brucei|Rep: Homocysteine
S-methyltransferase, putative - Trypanosoma brucei
Length = 433
Score = 48.4 bits (110), Expect = 2e-04
Identities = 64/226 (28%), Positives = 93/226 (41%), Gaps = 36/226 (15%)
Frame = +3
Query: 123 EIMSNFEVSSKT--VFVLDGGFSTQLT-CHAGHTADGDPLWSARFLKTHPQDVINTHLDF 293
E S FE S K F +DG T + C + G +WS L T + V H +
Sbjct: 10 ETGSIFEKSKKFQHFFTMDGAVGTLVERCGLDPSKMGS-MWSTSALITDEEIVRYVHKSY 68
Query: 294 LRAGSDIIETNTYQASVDGFVKH---LNLTVEESYELIKSAVEFARTARD----LYLQEC 452
L G+D+I TNTYQ G + +N V + ++ + R A ++ Q
Sbjct: 69 LDVGADVILTNTYQMHAAGCAQAGVTMNEVVNTAVRVLCDGITPERAAATKEAKVWAQHV 128
Query: 453 QESNLS-----------------GRKP-LIAGSVGPYGAYLHDTSEYTGNYADNTTKETI 578
+ S + P L+ GS+G YGA L + EY G Y N ++ I
Sbjct: 129 MNNKRSEFVNVFAPLFYGPRDDASKCPVLVGGSLGSYGASLGNAQEYRGEYEVN--EDII 186
Query: 579 KNWHRTRIQALV------EA--GVDILAFETIPCQKEAEALVEILK 692
++++ R A V EA VD + ETIP EA + LK
Sbjct: 187 RDYYVGRFMAFVNHVDEKEAHLKVDFIMIETIPLLNEAIEIFTWLK 232
>UniRef50_A5WFJ9 Cluster: Homocysteine S-methyltransferase; n=32;
Proteobacteria|Rep: Homocysteine S-methyltransferase -
Psychrobacter sp. PRwf-1
Length = 310
Score = 48.0 bits (109), Expect = 2e-04
Identities = 35/118 (29%), Positives = 59/118 (50%)
Frame = +3
Query: 144 VSSKTVFVLDGGFSTQLTCHAGHTADGDPLWSARFLKTHPQDVINTHLDFLRAGSDIIET 323
+S K + ++DGG +L P WSA + P+ V + H DF+R+G+ +I T
Sbjct: 1 MSVKAITIIDGGMGRELAKRGAPFRQ--PEWSALAMIEAPEIVRDVHRDFIRSGAGVITT 58
Query: 324 NTYQASVDGFVKHLNLTVEESYELIKSAVEFARTARDLYLQECQESNLSGRKPLIAGS 497
N+Y A + + + + + +L SA E AR A +L E + ++G P + GS
Sbjct: 59 NSY-ALLPFHIGEVRF-AKHAQDLAASAGEMARAAVEL---ENTPTKVAGSIPPLFGS 111
>UniRef50_Q748T0 Cluster: 5-methyltetrahydrofolate-homocysteine
methyltransferase, truncation; n=8;
Desulfuromonadales|Rep:
5-methyltetrahydrofolate-homocysteine methyltransferase,
truncation - Geobacter sulfurreducens
Length = 804
Score = 47.6 bits (108), Expect = 3e-04
Identities = 50/182 (27%), Positives = 77/182 (42%)
Frame = +3
Query: 150 SKTVFVLDGGFSTQLTCHAGHTADGDPLWSARFLKTHPQDVINTHLDFLRAGSDIIETNT 329
++ V VLDG T L G P T P+ V H ++L AG+DII TNT
Sbjct: 10 AERVLVLDGAMGTMLQ-ERGLRPGQSP---EELNLTLPEVVAGVHREYLDAGADIIVTNT 65
Query: 330 YQASVDGFVKHLNLTVEESYELIKSAVEFARTARDLYLQECQESNLSGRKPLIAGSVGPY 509
+ S ++H L + E+ AV AR + G + +A S+GP
Sbjct: 66 FGGS-RAKLEHYGLQ-DRVAEINARAVAIAR-------------EVCGDRAYVAASIGPT 110
Query: 510 GAYLHDTSEYTGNYADNTTKETIKNWHRTRIQALVEAGVDILAFETIPCQKEAEALVEIL 689
G ++ + + + + R + QAL+ AG D++ ET KE A V +
Sbjct: 111 GQFVEPVGD--------VSFDEMAAIFREQAQALINAGADLITLETFLDIKEIRAAVIAI 162
Query: 690 KE 695
+E
Sbjct: 163 RE 164
>UniRef50_A4J6L9 Cluster: Homocysteine S-methyltransferase; n=1;
Desulfotomaculum reducens MI-1|Rep: Homocysteine
S-methyltransferase - Desulfotomaculum reducens MI-1
Length = 800
Score = 47.6 bits (108), Expect = 3e-04
Identities = 49/166 (29%), Positives = 74/166 (44%), Gaps = 1/166 (0%)
Frame = +3
Query: 153 KTVFVLDGGFSTQLTCHAGHTADGDPLWSARFLKTHPQDVINTHLDFLRAGSDIIETNTY 332
K V ++DG T L W+ +HP+ V H +L AG+DII TNT+
Sbjct: 9 KEVLIIDGAMGTLLQQRGLPGGWCPEEWNL----SHPEAVKEIHKLYLEAGADIITTNTF 64
Query: 333 QASVDGFVK-HLNLTVEESYELIKSAVEFARTARDLYLQECQESNLSGRKPLIAGSVGPY 509
A HL V+E + ++AV+ A+ Y ++AGSVGP
Sbjct: 65 GAIQLKLADYHLGDQVKE---INQAAVKLAKEVAQPY------------GAMVAGSVGPL 109
Query: 510 GAYLHDTSEYTGNYADNTTKETIKNWHRTRIQALVEAGVDILAFET 647
G +L T +E + ++ + A+VEAGVD++ FET
Sbjct: 110 GKFLQPLGTMT-------FEEAYQQFYE-QCAAMVEAGVDLILFET 147
>UniRef50_A7CWS4 Cluster: Homocysteine S-methyltransferase
precursor; n=7; Bacteria|Rep: Homocysteine
S-methyltransferase precursor - Opitutaceae bacterium
TAV2
Length = 398
Score = 47.2 bits (107), Expect = 4e-04
Identities = 37/133 (27%), Positives = 60/133 (45%), Gaps = 1/133 (0%)
Frame = +3
Query: 255 THPQDVINTHLDFLRAGSDIIETNTYQA-SVDGFVKHLNLTVEESYELIKSAVEFARTAR 431
T P + H + AG+D++ETNT+ + ++ HL V E+ +A AR A
Sbjct: 98 TRPDVIEGIHAAYFAAGADMVETNTFNSTAISQADYHLEPLVT---EINTAAAAIARRA- 153
Query: 432 DLYLQECQESNLSGRKPLIAGSVGPYGAYLHDTSEYTGNYADNTTKETIKNWHRTRIQAL 611
E+ GR+ +AG++GP L + + T + + +I+AL
Sbjct: 154 ----VRATETATPGRRCFVAGAIGPLNRTLSMSPDVNRPDYRAVTWAQVVAAYTEQIRAL 209
Query: 612 VEAGVDILAFETI 650
+ GVD L ETI
Sbjct: 210 IAGGVDALLVETI 222
>UniRef50_A3JFK5 Cluster: Putative uncharacterized protein; n=1;
Marinobacter sp. ELB17|Rep: Putative uncharacterized
protein - Marinobacter sp. ELB17
Length = 303
Score = 47.2 bits (107), Expect = 4e-04
Identities = 28/100 (28%), Positives = 47/100 (47%), Gaps = 5/100 (5%)
Frame = +3
Query: 153 KTVFVLDGGFSTQLTCHAGHTADGDPLWSARFLKTHPQDVINTHLDFLRAGSDIIETNTY 332
+ V +LDGG ++ A + + LWS + P V H DF+RAG+ + NTY
Sbjct: 2 RPVVLLDGGLGQEIYRRAANVSSA--LWSVAVMHEQPDVVTAVHSDFIRAGAKTLSLNTY 59
Query: 333 QASVDGFVKH-----LNLTVEESYELIKSAVEFARTARDL 437
A+ ++H L + ++EL+ AV+ D+
Sbjct: 60 AATPSRLLRHGQLEQLAAIHQNAFELLGQAVKATGACVDI 99
>UniRef50_A0Z513 Cluster: Putative uncharacterized protein; n=1;
marine gamma proteobacterium HTCC2080|Rep: Putative
uncharacterized protein - marine gamma proteobacterium
HTCC2080
Length = 306
Score = 46.8 bits (106), Expect = 6e-04
Identities = 30/88 (34%), Positives = 44/88 (50%)
Frame = +3
Query: 159 VFVLDGGFSTQLTCHAGHTADGDPLWSARFLKTHPQDVINTHLDFLRAGSDIIETNTYQA 338
+ +LDGG +L + A PLWS + + P+ V N H DF AG+ +I NTY
Sbjct: 5 ITLLDGGMGQELIRRSS-AAKPHPLWSLQVMMDEPELVANVHRDFCLAGARVICLNTY-- 61
Query: 339 SVDGFVKHLNLTVEESYELIKSAVEFAR 422
SV + + + EL+K A + AR
Sbjct: 62 SVTRHRLQMGNELPDLPELLKHAGDLAR 89
>UniRef50_A0LDY2 Cluster: Methionine synthase; n=54; Bacteria|Rep:
Methionine synthase - Magnetococcus sp. (strain MC-1)
Length = 1220
Score = 46.8 bits (106), Expect = 6e-04
Identities = 39/152 (25%), Positives = 67/152 (44%), Gaps = 5/152 (3%)
Frame = +3
Query: 255 THPQDVINTHLDFLRAGSDIIETNTYQASVDGFVKH-LNLTVEESYELIKSAVEFARTAR 431
T PQ + N H +L AG+DI+ETNT+ + + L V YE+ AR A
Sbjct: 63 TKPQVIRNIHTAYLEAGADIVETNTFNGNAPSLGDYGLEALV---YEVNLEGARVARQAC 119
Query: 432 DLYLQECQESNLSGRKPLIAGSVGPYGAYLHDTSEYTGNYADNTTKETIKNWHRTRIQAL 611
D + + GR +AG +GP + + N + + + + L
Sbjct: 120 DAVM-----AQQPGRICFVAGVLGPTNRTCSISPDVNNPGFRNIDFDALVADYANGTRGL 174
Query: 612 VEAGVDIL----AFETIPCQKEAEALVEILKE 695
++ G DIL F+T+ C+ A+ ++L++
Sbjct: 175 LDGGADILLVETVFDTLNCKAALFAVRQVLEQ 206
>UniRef50_Q9WYA5 Cluster: 5-methyltetrahydrofolate S-homocysteine
methyltransferase; n=2; Thermotoga|Rep:
5-methyltetrahydrofolate S-homocysteine
methyltransferase - Thermotoga maritima
Length = 768
Score = 46.4 bits (105), Expect = 7e-04
Identities = 52/183 (28%), Positives = 85/183 (46%), Gaps = 1/183 (0%)
Frame = +3
Query: 150 SKTVFVLDGGFSTQLTCHAGHTADGDPLWSARFLKTHPQDVINTHLDFLRAGSDIIETNT 329
S+ V +LDG + T+ + G+ D L +K P V+ H ++ +GSD+I TNT
Sbjct: 12 SERVLLLDGAYGTEFMKY-GY----DDLPEELNIKA-PDVVLKVHRSYIESGSDVILTNT 65
Query: 330 YQASVDGFVKHLNLTVEESYE-LIKSAVEFARTARDLYLQECQESNLSGRKPLIAGSVGP 506
+ A+ KH +E+ + ++++AV AR A +G K L+ G +GP
Sbjct: 66 FGATRMKLRKH---GLEDKLDPIVRNAVRIARRA-------------AGEK-LVFGDIGP 108
Query: 507 YGAYLHDTSEYTGNYADNTTKETIKNWHRTRIQALVEAGVDILAFETIPCQKEAEALVEI 686
T E +E +N+ T ++ +VE GVD + FET E +A V
Sbjct: 109 -------TGELPYPLGSTLFEEFYENFRET-VEIMVEEGVDGIIFETFSDILELKAAVLA 160
Query: 687 LKE 695
+E
Sbjct: 161 ARE 163
>UniRef50_Q93088 Cluster: Betaine--homocysteine S-methyltransferase
1; n=61; Eumetazoa|Rep: Betaine--homocysteine
S-methyltransferase 1 - Homo sapiens (Human)
Length = 406
Score = 46.4 bits (105), Expect = 7e-04
Identities = 30/94 (31%), Positives = 47/94 (50%), Gaps = 2/94 (2%)
Frame = +3
Query: 159 VFVLDGGFSTQLTCHAGHTADGDPLWSARFLKTHPQDVINTHLDFLRAGSDIIETNTYQA 338
+ + DGGF L G+ G W+ HP+ V H +FLRAGS++++T T+ A
Sbjct: 22 IVIGDGGFVFALE-KRGYVKAGP--WTPEAAVEHPEAVRQLHREFLRAGSNVMQTFTFYA 78
Query: 339 SVDGFVKHLNLTVEE--SYELIKSAVEFARTARD 434
S D N +E+ E+ ++A + AR D
Sbjct: 79 SEDKLENRGNYVLEKISGQEVNEAACDIARQVAD 112
>UniRef50_Q55786 Cluster: Methionine synthase; n=5;
Cyanobacteria|Rep: Methionine synthase - Synechocystis
sp. (strain PCC 6803)
Length = 1195
Score = 46.0 bits (104), Expect = 0.001
Identities = 47/173 (27%), Positives = 77/173 (44%), Gaps = 4/173 (2%)
Frame = +3
Query: 153 KTVFVLDGGFSTQLTCHAGHTAD-GDPLWSA---RFLKTHPQDVINTHLDFLRAGSDIIE 320
+ V V DG T L AD G + + T P+ V H F AG+D++E
Sbjct: 14 RPVLVFDGAMGTNLQVQNLTAADFGGAEYEGCNEYLVHTKPEAVATVHRAFYEAGADVVE 73
Query: 321 TNTYQASVDGFVKHLNLTVEESYELIKSAVEFARTARDLYLQECQESNLSGRKPLIAGSV 500
T+T+ + +L ++SY L K+A E A+ E + + +AGS+
Sbjct: 74 TDTF-GGTPLVLAEYDL-ADQSYYLNKAAAELAKAV-------AAEFSTPEKPRFVAGSM 124
Query: 501 GPYGAYLHDTSEYTGNYADNTTKETIKNWHRTRIQALVEAGVDILAFETIPCQ 659
GP T T + D +++K+ + +++ L + GVD+L ET CQ
Sbjct: 125 GP------GTKLPTLGHVD---YDSLKDAYVVQVRGLYDGGVDLLLVET--CQ 166
>UniRef50_A7H6G1 Cluster: Methionine synthase; n=3; Bacteria|Rep:
Methionine synthase - Anaeromyxobacter sp. Fw109-5
Length = 1149
Score = 45.6 bits (103), Expect = 0.001
Identities = 48/182 (26%), Positives = 70/182 (38%), Gaps = 2/182 (1%)
Frame = +3
Query: 141 EVSSKTVFVLDGGFSTQLTCHAGHTADGDPLWSARFLKT--HPQDVINTHLDFLRAGSDI 314
E + V DG TQ+ H A+ A L T P V + H + G D+
Sbjct: 5 EAIDRRPLVFDGAMGTQIQRHQLTAAEFGGKDGANDLLTLTRPDLVEDIHARYFAVGCDV 64
Query: 315 IETNTYQASVDGFVKHLNLTVEESYELIKSAVEFARTARDLYLQECQESNLSGRKPLIAG 494
+ETNT+ +S L ++E Y L E A L + + +AG
Sbjct: 65 VETNTFGSS--------RLKLDE-YGLGHRTYEVNFRAAILARRAAERFATPDHPRFVAG 115
Query: 495 SVGPYGAYLHDTSEYTGNYADNTTKETIKNWHRTRIQALVEAGVDILAFETIPCQKEAEA 674
S+GP G + G N T + ++ + + L+E GVD L ET E A
Sbjct: 116 SMGPTGMLPSSSDPALG----NITSDALERIFFEQAKGLIEGGVDALIIETQQDMLELRA 171
Query: 675 LV 680
V
Sbjct: 172 AV 173
>UniRef50_A6DGP4 Cluster: 5-methyltetrahydrofolate--homocysteine
methyltransferase; n=1; Lentisphaera araneosa
HTCC2155|Rep: 5-methyltetrahydrofolate--homocysteine
methyltransferase - Lentisphaera araneosa HTCC2155
Length = 1204
Score = 45.6 bits (103), Expect = 0.001
Identities = 53/206 (25%), Positives = 89/206 (43%), Gaps = 22/206 (10%)
Frame = +3
Query: 129 MSNFEVSSKTVFVLDG--GFSTQLTCHAGHTADGDP--LWSARFLKTHPQDVI-NTHLDF 293
M + + + VLDG G QL G+ + S + + P V N HL++
Sbjct: 1 MKFLDALKEQILVLDGAMGSMVQLLKLPDSAYGGEEYAMLSDLLVFSRPDQVRDNIHLEY 60
Query: 294 LRAGSDIIETNTYQAS-------------VDGFV---KHLNLTVEESYELIKSA-VEFAR 422
L+AG++I+ETNT+ AS + F + L+ + Y L +
Sbjct: 61 LKAGANILETNTFGASPLRLQEFDFSKMDLSDFADLPEGLDFLENDYYALTHYFNIRGIE 120
Query: 423 TARDLYLQECQESNLSGRKPLIAGSVGPYGAYLHDTSEYTGNYADNTTKETIKNWHRTRI 602
A+D + + GR +AGS+GP + T+ + T TIK ++
Sbjct: 121 LAQDAIEKYKKMDEYDGRPLFVAGSIGPSNWVISSTAANL----NKTDFATIKQNFYLQV 176
Query: 603 QALVEAGVDILAFETIPCQKEAEALV 680
+A+++A VD+L FET E +A +
Sbjct: 177 KAMMQANVDVLLFETQQDMLELKASI 202
>UniRef50_A3UPV1 Cluster: Homocysteine S-methyltransferase family
protein; n=6; Vibrionales|Rep: Homocysteine
S-methyltransferase family protein - Vibrio splendidus
12B01
Length = 299
Score = 45.6 bits (103), Expect = 0.001
Identities = 32/94 (34%), Positives = 47/94 (50%)
Frame = +3
Query: 153 KTVFVLDGGFSTQLTCHAGHTADGDPLWSARFLKTHPQDVINTHLDFLRAGSDIIETNTY 332
KT+ +LDGG +L PLWSA+ L P+ V H +F+ AG++I+ TN+Y
Sbjct: 2 KTLTILDGGMGRELK--EIDAPFSQPLWSAQALIEAPEFVSQAHQNFVDAGAEILITNSY 59
Query: 333 QASVDGFVKHLNLTVEESYELIKSAVEFARTARD 434
A V F L + +EL + E A+ D
Sbjct: 60 -ACVP-FHLGEELFEQRGFELAAQSGELAKAVAD 91
>UniRef50_A3S2V2 Cluster: 5-methyltetrahydrofolate--homocysteine
methyltransferase; n=1; Prochlorococcus marinus str. MIT
9211|Rep: 5-methyltetrahydrofolate--homocysteine
methyltransferase - Prochlorococcus marinus str. MIT
9211
Length = 1191
Score = 45.6 bits (103), Expect = 0.001
Identities = 46/172 (26%), Positives = 77/172 (44%), Gaps = 4/172 (2%)
Frame = +3
Query: 156 TVFVLDGGFSTQLTCHAGHTAD--GDPLWSAR--FLKTHPQDVINTHLDFLRAGSDIIET 323
T+ V DGG T L D G L ++P+ V H +L G D+IET
Sbjct: 12 TILVFDGGMGTALQLQELSKEDFGGSQFEGCNEYLLISNPKSVEKVHRSYLEVGCDVIET 71
Query: 324 NTYQASVDGFVKHLNLTVEESYELIKSAVEFARTARDLYLQECQESNLSGRKPLIAGSVG 503
NT+ A+ + L ++Y+L +A + A+T +E + + AGS+G
Sbjct: 72 NTFGAT-SVVLAEYGLE-NKAYQLNLAASKMAKTL-------AKEYSTINKPRYAAGSIG 122
Query: 504 PYGAYLHDTSEYTGNYADNTTKETIKNWHRTRIQALVEAGVDILAFETIPCQ 659
P T T + D + + N ++ +++AL+ G+D++ ET CQ
Sbjct: 123 P------TTKLPTLGHID---FDDLTNSYQEQVEALITGGIDLVLVET--CQ 163
>UniRef50_Q6AL45 Cluster: Related to
5-methyltetrahydrofolate--homocysteine
methyltransferase; n=1; Desulfotalea psychrophila|Rep:
Related to 5-methyltetrahydrofolate--homocysteine
methyltransferase - Desulfotalea psychrophila
Length = 316
Score = 45.2 bits (102), Expect = 0.002
Identities = 50/174 (28%), Positives = 86/174 (49%), Gaps = 3/174 (1%)
Frame = +3
Query: 147 SSKTVFVLDGGFSTQL-TCHAGHTADGDPLWSARFLK-THPQDVINTHLDFLRAGSDIIE 320
+ +++ + DG T L + + +A GD FL + P+ +I H FL AG+ ++E
Sbjct: 4 TDESLLIFDGACGTTLQSMNIAPSAWGDLAGCNEFLNISAPEYIIELHKKFLEAGAMVVE 63
Query: 321 TNTYQASVDGFVKH-LNLTVEESYELIKSAVEFARTARDLYLQECQESNLSGRKPLIAGS 497
TNT+ AS ++ L V+ E+ + AV+ A+ A + + ++S+ + IAGS
Sbjct: 64 TNTFGASSIVLTEYGLENKVD---EINREAVKNAKKA----ISQLKDSS---QPRYIAGS 113
Query: 498 VGPYGAYLHDTSEYTGNYADNTTKETIKNWHRTRIQALVEAGVDILAFETIPCQ 659
+GP G+ ++I R ++ +L+EAGVD L ET CQ
Sbjct: 114 IGP-----TTKLPSLGHIETKVLAQSI----REQVISLLEAGVDALIVET--CQ 156
>UniRef50_A3ERA3 Cluster: Methionine synthase I, cobalamin-binding
domain; n=2; Leptospirillum|Rep: Methionine synthase I,
cobalamin-binding domain - Leptospirillum sp. Group II
UBA
Length = 815
Score = 45.2 bits (102), Expect = 0.002
Identities = 49/184 (26%), Positives = 81/184 (44%), Gaps = 2/184 (1%)
Frame = +3
Query: 159 VFVLDGGFSTQLTCHAGHTADGDPLWSARFLKTHPQDVINTHLDFLRAGSDIIETNTYQA 338
+ +LDG L LW+ PQD+ H +++ AGSDII TNT+ +
Sbjct: 12 ILLLDGSMGALLQSRGLPPGYAPDLWNLE----RPQDIQQVHSEYVEAGSDIILTNTFGS 67
Query: 339 SVDGFVKHLNLTVE-ESYELIKSAVEFARTARDLYLQECQESNLSGRKPLIAGSVGPYGA 515
S ++ E + E+ ++ VE AR A S K +AG +GP G
Sbjct: 68 S---RLRLREYDAEGQIREINEAGVEMARRA-------------SRGKAYVAGDIGPSGT 111
Query: 516 YLHDTSEYTGNYADNTTKETIKNWHRTRIQALVEAGVDILAFETI-PCQKEAEALVEILK 692
+ + D + I ++ + + L+EAGVD++A ET+ Q+ AL+ + +
Sbjct: 112 TI-------APFGDLPFDDAIGIFYE-QARILLEAGVDLIAIETMFDIQEMRAALIGVRE 163
Query: 693 EYPN 704
N
Sbjct: 164 AVGN 167
>UniRef50_Q9I2Q2 Cluster: Methionine synthase; n=95; Bacteria|Rep:
Methionine synthase - Pseudomonas aeruginosa
Length = 1234
Score = 45.2 bits (102), Expect = 0.002
Identities = 48/187 (25%), Positives = 84/187 (44%), Gaps = 13/187 (6%)
Frame = +3
Query: 159 VFVLDGGFSTQLTCHAGHTAD--GDPL--WSAR-------FLKTHPQDVINTHLDFLRAG 305
+ +LDGG T + + AD G+ W + L + P + +L AG
Sbjct: 23 ILILDGGMGTMIQSYKLEEADYRGERFADWPSDVKGNNDLLLLSRPDVIQAIEKAYLDAG 82
Query: 306 SDIIETNTYQASVDGFVKHLNLTVEE-SYELIKSAVEFARTARDLYLQECQESNLSGRKP 482
+DI+ETNT+ A+ V + ++ +YEL VE AR AR + + + + +
Sbjct: 83 ADILETNTFNATQ---VSQADYGMQSLAYEL---NVEGARLARQ--VADAKTAETPDKPR 134
Query: 483 LIAGSVGPYGAYLHDTSEYTG-NYADNTTKETIKNWHRTRIQALVEAGVDILAFETIPCQ 659
+AG +GP + + Y + T E ++N+ + L+E G D++ ETI
Sbjct: 135 FVAGVLGPTSRTCSISPDVNNPGYRNVTFDELVENYVEA-TRGLIEGGADLILIETIFDT 193
Query: 660 KEAEALV 680
A+A +
Sbjct: 194 LNAKAAI 200
>UniRef50_Q88X64 Cluster: Methylenetetrahydrofolate reductase; n=1;
Lactobacillus plantarum|Rep: Methylenetetrahydrofolate
reductase - Lactobacillus plantarum
Length = 618
Score = 44.8 bits (101), Expect = 0.002
Identities = 23/61 (37%), Positives = 38/61 (62%), Gaps = 1/61 (1%)
Frame = +3
Query: 255 THPQDVINTHLDFLRAGSDIIETNTYQASVDGFVKHLNLTVEESYELI-KSAVEFARTAR 431
THP ++ H ++RAG+DII+TNTY A+ +K +++ I ++AV+ A TAR
Sbjct: 38 THPDTILRVHRSYIRAGADIIQTNTYAAN---RLKLTRYDLQDQVTTINQAAVKIAATAR 94
Query: 432 D 434
+
Sbjct: 95 E 95
>UniRef50_Q2JJL4 Cluster: Methionine synthase; n=25;
Cyanobacteria|Rep: Methionine synthase - Synechococcus
sp. (strain JA-2-3B'a(2-13)) (Cyanobacteria
bacteriumYellowstone B-Prime)
Length = 1224
Score = 44.8 bits (101), Expect = 0.002
Identities = 52/188 (27%), Positives = 83/188 (44%), Gaps = 8/188 (4%)
Frame = +3
Query: 159 VFVLDGGFSTQLTCHAGHTAD-GDPLWSA---RFLKTHPQDVINTHLDFLRAGSDIIETN 326
V V DG + L AD G P + T P+ V H FL G+D++ETN
Sbjct: 13 VIVFDGAMGSSLQAQNLTAADFGGPELEGCNEMLVLTKPEAVERVHRGFLEVGADVVETN 72
Query: 327 TYQASVDGFVKHLNLTVEESYELIKSAVEFA-RTARDLYLQECQESNLSGRKPLIAGSVG 503
T+ A+ V E++YEL +A A R A + E + +AGS+G
Sbjct: 73 TFGAT--SIVLAEYGIPEKAYELNVAAARLAKRVAAEFATPE--------KPRFVAGSIG 122
Query: 504 PYGAYLHDTSEYTGNYADNTTKETIKNWHRTRIQALVEAGVDILAFETIPCQ---KEAEA 674
P T++ + + + ++ + ++Q LV+ G D+L ET CQ + A
Sbjct: 123 P-------TTKLP--TLGHISFDEMRAAYEEQVQGLVDGGADLLIIET--CQDILQTKAA 171
Query: 675 LVEILKEY 698
LV + +E+
Sbjct: 172 LVAVQQEF 179
>UniRef50_Q1GGL5 Cluster: Homocysteine S-methyltransferase; n=30;
Bacteria|Rep: Homocysteine S-methyltransferase -
Silicibacter sp. (strain TM1040)
Length = 340
Score = 44.8 bits (101), Expect = 0.002
Identities = 47/183 (25%), Positives = 77/183 (42%)
Frame = +3
Query: 144 VSSKTVFVLDGGFSTQLTCHAGHTADGDPLWSARFLKTHPQDVINTHLDFLRAGSDIIET 323
+ S+ V + DG T L + D LW+ P + + + AGSD+ T
Sbjct: 9 LDSRDVLLADGATGTNLFNMGLQSGDAPELWNT----DAPDKIKALYQGSVDAGSDLFLT 64
Query: 324 NTYQASVDGFVKHLNLTVEESYELIKSAVEFARTARDLYLQECQESNLSGRKPLIAGSVG 503
N++ + L + ++ ++ E R A +L + ++ RK +AGSVG
Sbjct: 65 NSFGGTA------ARLKLHDAQGRVR---ELNRIAAELGREVADKAE---RKIAVAGSVG 112
Query: 504 PYGAYLHDTSEYTGNYADNTTKETIKNWHRTRIQALVEAGVDILAFETIPCQKEAEALVE 683
P G + E + A ++ +H + AL E GVD+L ETI +E A E
Sbjct: 113 PTGEIMQPVGELSHALA-------VEMFHE-QADALKEGGVDVLWLETISAPEEFAAAAE 164
Query: 684 ILK 692
K
Sbjct: 165 AFK 167
>UniRef50_Q8DCJ7 Cluster: Methionine synthase; n=51; Bacteria|Rep:
Methionine synthase - Vibrio vulnificus
Length = 1226
Score = 44.8 bits (101), Expect = 0.002
Identities = 35/132 (26%), Positives = 59/132 (44%)
Frame = +3
Query: 255 THPQDVINTHLDFLRAGSDIIETNTYQASVDGFVKHLNLTVEESYELIKSAVEFARTARD 434
T PQ + H +L AG+DI+ETNT+ A+ + ++ E E+ +A AR A D
Sbjct: 60 TQPQLIKEIHHAYLEAGADILETNTFNATTIAMADYDMESLSE--EINFAAARLAREAAD 117
Query: 435 LYLQECQESNLSGRKPLIAGSVGPYGAYLHDTSEYTGNYADNTTKETIKNWHRTRIQALV 614
E N + +AG +GP + + N + + + + +AL+
Sbjct: 118 ----EWTAQN-PAKPRYVAGVLGPTNRTCSISPDVNDPGYRNVSFDELVEAYSESTRALI 172
Query: 615 EAGVDILAFETI 650
G D++ ETI
Sbjct: 173 RGGSDLILIETI 184
>UniRef50_A7N4Y4 Cluster: Putative uncharacterized protein; n=1;
Vibrio harveyi ATCC BAA-1116|Rep: Putative
uncharacterized protein - Vibrio harveyi ATCC BAA-1116
Length = 301
Score = 44.0 bits (99), Expect = 0.004
Identities = 31/94 (32%), Positives = 49/94 (52%)
Frame = +3
Query: 153 KTVFVLDGGFSTQLTCHAGHTADGDPLWSARFLKTHPQDVINTHLDFLRAGSDIIETNTY 332
K + +LDGG +L + + PLWSA+ L P+ V H +F++AG++II N+Y
Sbjct: 2 KKLTILDGGMGRELKRMSAPFSQ--PLWSAQALIESPEFVYQAHDNFIQAGAEIIIANSY 59
Query: 333 QASVDGFVKHLNLTVEESYELIKSAVEFARTARD 434
A V F L ++ +L + A + AR D
Sbjct: 60 -ACVP-FHLGQELYDQQGSKLARFAAKIARECAD 91
>UniRef50_A0VUF3 Cluster: Homocysteine S-methyltransferase; n=5;
Alphaproteobacteria|Rep: Homocysteine
S-methyltransferase - Dinoroseobacter shibae DFL 12
Length = 350
Score = 44.0 bits (99), Expect = 0.004
Identities = 24/63 (38%), Positives = 30/63 (47%)
Frame = +3
Query: 159 VFVLDGGFSTQLTCHAGHTADGDPLWSARFLKTHPQDVINTHLDFLRAGSDIIETNTYQA 338
+ +LDGG +L AG PLWS L P V H DF AG+++ TNTY
Sbjct: 45 ITLLDGGLGQELVRRAGRAT---PLWSMEALLNAPDLVRAVHDDFFAAGAEVATTNTYAV 101
Query: 339 SVD 347
D
Sbjct: 102 LPD 104
>UniRef50_Q5LN14 Cluster: Homocysteine S-methyltransferase family
protein; n=9; Rhodobacteraceae|Rep: Homocysteine
S-methyltransferase family protein - Silicibacter
pomeroyi
Length = 298
Score = 43.2 bits (97), Expect = 0.007
Identities = 39/120 (32%), Positives = 56/120 (46%), Gaps = 1/120 (0%)
Frame = +3
Query: 159 VFVLDGGFSTQLTCHAGHTADGDPLWSARFLKTHPQDVINTHLDFLRAGSDIIETNTYQA 338
+ +LDG +L AG PLWS + P V H D+ AG+ I TNTY
Sbjct: 4 ITLLDGSIGQELVKRAGKRPT--PLWSTSVMLEAPYHVGAVHRDYFDAGATIATTNTYAV 61
Query: 339 SVDGFVKHLNLTVEESYE-LIKSAVEFARTARDLYLQECQESNLSGRKPLIAGSVGPYGA 515
D + + +E LI +A++ A +AR ++ SGR IAG++GP GA
Sbjct: 62 LRDRLEP---AGIGDRFEALIDTALDQAESAR--------AAHGSGR---IAGALGPLGA 107
>UniRef50_Q1IL23 Cluster: Methylenetetrahydrofolate reductase; n=2;
Acidobacteria|Rep: Methylenetetrahydrofolate reductase -
Acidobacteria bacterium (strain Ellin345)
Length = 617
Score = 43.2 bits (97), Expect = 0.007
Identities = 33/131 (25%), Positives = 64/131 (48%)
Frame = +3
Query: 255 THPQDVINTHLDFLRAGSDIIETNTYQASVDGFVKHLNLTVEESYELIKSAVEFARTARD 434
+ P+ + H D++ G++I+ETNT+ A+ +H E+ ++ ++ VE R A
Sbjct: 41 SQPELIGGIHADYVANGAEILETNTFGANSFRLARH--GCQEKLADINRAGVELVRKA-- 96
Query: 435 LYLQECQESNLSGRKPLIAGSVGPYGAYLHDTSEYTGNYADNTTKETIKNWHRTRIQALV 614
+ + AG+VGP G + + T+++ ++ R +I+ LV
Sbjct: 97 ----------IKNNQVYAAGAVGPLGIRIEPLGK--------TSRDEARDAFRDQIRVLV 138
Query: 615 EAGVDILAFET 647
++GVD+L ET
Sbjct: 139 DSGVDLLILET 149
>UniRef50_Q4Y025 Cluster: Putative uncharacterized protein; n=4;
Plasmodium (Vinckeia)|Rep: Putative uncharacterized
protein - Plasmodium chabaudi
Length = 504
Score = 43.2 bits (97), Expect = 0.007
Identities = 21/61 (34%), Positives = 38/61 (62%)
Frame = +3
Query: 264 QDVINTHLDFLRAGSDIIETNTYQASVDGFVKHLNLTVEESYELIKSAVEFARTARDLYL 443
+++ N HL +L +GS+II TNTYQ ++ K N+++E E+I + ++ A + + Y
Sbjct: 41 ENLKNIHLSYLLSGSNIITTNTYQVNL--HFKRNNISIENGKEIIDTYIDIAYESCEKYK 98
Query: 444 Q 446
Q
Sbjct: 99 Q 99
>UniRef50_Q7M929 Cluster: S-METHYLTRANSFERASE; n=1; Wolinella
succinogenes|Rep: S-METHYLTRANSFERASE - Wolinella
succinogenes
Length = 1120
Score = 42.7 bits (96), Expect = 0.009
Identities = 50/188 (26%), Positives = 79/188 (42%), Gaps = 2/188 (1%)
Frame = +3
Query: 138 FEVSSKTVFVLDGGFSTQLTCHAGHTADGDP-LWSARFLKTHPQDVI-NTHLDFLRAGSD 311
FE+ + V +LDG T++ D + + L DVI + H +L AG+D
Sbjct: 7 FEIHRQRVMILDGAMGTEIQKFDLKEEDWEEKAGCSEILNVTRGDVILSIHRSYLEAGAD 66
Query: 312 IIETNTYQASVDGFVKHLNLTVEESYELIKSAVEFARTARDLYLQECQESNLSGRKPLIA 491
I+++NT+ A L +EE Y + A E A + + C S R +A
Sbjct: 67 ILKSNTFGA--------LPWVLEE-YGIGGRAYEMAFAGAQIAKEACDSFAPSPR--FVA 115
Query: 492 GSVGPYGAYLHDTSEYTGNYADNTTKETIKNWHRTRIQALVEAGVDILAFETIPCQKEAE 671
GS+GP G L +Y +T+ ++ + L E G D+ ET + +
Sbjct: 116 GSLGP-GTKLPSLGHI--DY------DTMFEGYKEAARGLKEGGADLFLLETCQDPLQIK 166
Query: 672 ALVEILKE 695
A V KE
Sbjct: 167 AAVHACKE 174
>UniRef50_A6PRW5 Cluster: Methylenetetrahydrofolate reductase; n=1;
Victivallis vadensis ATCC BAA-548|Rep:
Methylenetetrahydrofolate reductase - Victivallis
vadensis ATCC BAA-548
Length = 595
Score = 42.7 bits (96), Expect = 0.009
Identities = 42/158 (26%), Positives = 79/158 (50%)
Frame = +3
Query: 255 THPQDVINTHLDFLRAGSDIIETNTYQASVDGFVKHLNLTVEESYELIKSAVEFARTARD 434
T P +++ H +L+AG++++ TNTY A+ K L+ E++ + ++ V+ AR A
Sbjct: 30 TAPDVILDIHHQYLKAGAEVLTTNTYNANSRRLAK-FGLS-EQTEAINRAGVKLAREA-- 85
Query: 435 LYLQECQESNLSGRKPLIAGSVGPYGAYLHDTSEYTGNYADNTTKETIKNWHRTRIQALV 614
+ K L+A SVGP G D+ + D T+ + +I+AL
Sbjct: 86 -----------AAGKALVAASVGPVGE--PDSDQ------DRRTRAELL---AEQIRALS 123
Query: 615 EAGVDILAFETIPCQKEAEALVEILKEYPNMKAWLSFS 728
+A D + FE++ + +A++E + E+P + SF+
Sbjct: 124 DA--DFIIFESLRRAADLKAVLEAVAEFPELVYVPSFA 159
>UniRef50_A7DNT5 Cluster: Homocysteine S-methyltransferase; n=1;
Candidatus Nitrosopumilus maritimus SCM1|Rep:
Homocysteine S-methyltransferase - Candidatus
Nitrosopumilus maritimus SCM1
Length = 320
Score = 42.7 bits (96), Expect = 0.009
Identities = 38/143 (26%), Positives = 61/143 (42%)
Frame = +3
Query: 255 THPQDVINTHLDFLRAGSDIIETNTYQASVDGFVKHLNLTVEESYELIKSAVEFARTARD 434
T P + H +L AG+D IETN++ ++ + ++E Y +EF +
Sbjct: 50 TRPDWIKQIHRHYLDAGADCIETNSFGSN--------KIKLDE-YGFGDQTIEFNKKIAQ 100
Query: 435 LYLQECQESNLSGRKPLIAGSVGPYGAYLHDTSEYTGNYADNTTKETIKNWHRTRIQALV 614
L + CQE S R + GS+GP G G + KE + + + L+
Sbjct: 101 LASEVCQE--YSDRPRYVIGSMGPSGFLPSSNDPDLGQKPLDEIKEAFE----LQAEGLI 154
Query: 615 EAGVDILAFETIPCQKEAEALVE 683
GVD L ET E + ++E
Sbjct: 155 LGGVDALLIETSQDILEVKLVIE 177
>UniRef50_A6TTI3 Cluster: Homocysteine S-methyltransferase; n=2;
Clostridiales|Rep: Homocysteine S-methyltransferase -
Alkaliphilus metalliredigens QYMF
Length = 789
Score = 41.9 bits (94), Expect = 0.016
Identities = 40/146 (27%), Positives = 67/146 (45%)
Frame = +3
Query: 258 HPQDVINTHLDFLRAGSDIIETNTYQASVDGFVKHLNLTVEESYELIKSAVEFARTARDL 437
HP+ + H F+RAG+ ++ TNT+QA+ L ++ E+I+ ++ A+
Sbjct: 40 HPELIQQIHERFVRAGAQVVTTNTFQAN----ELKLKDSIYSLEEIIEGGIKVAKA---- 91
Query: 438 YLQECQESNLSGRKPLIAGSVGPYGAYLHDTSEYTGNYADNTTKETIKNWHRTRIQALVE 617
SG P +A +GP G + E + + A + K ++QA V+
Sbjct: 92 ----------SG-APYVALDIGPLGQMMKPLGEISFDRAYDIFKR--------QVQAGVK 132
Query: 618 AGVDILAFETIPCQKEAEALVEILKE 695
AG D + ETI EA+A + KE
Sbjct: 133 AGADCILIETISDLYEAKAAILAAKE 158
>UniRef50_Q9KCE1 Cluster: 5-methyltetrahydrofolate S-homocysteine
methyltransferase; n=21; Bacteria|Rep:
5-methyltetrahydrofolate S-homocysteine
methyltransferase - Bacillus halodurans
Length = 1146
Score = 41.5 bits (93), Expect = 0.021
Identities = 48/179 (26%), Positives = 76/179 (42%), Gaps = 5/179 (2%)
Frame = +3
Query: 153 KTVFVLDGGFSTQLTCHAGHTAD---GDPLWSAR-FL-KTHPQDVINTHLDFLRAGSDII 317
+ + +LDG T L A TAD G+ +L +T P V + H +L AG+D+I
Sbjct: 12 RKIVILDGAMGTMLQA-ANLTADDFGGEEYEGCNEYLNETAPHVVEDIHRAYLEAGADVI 70
Query: 318 ETNTYQASVDGFVKHLNLTVEESYELIKSAVEFARTARDLYLQECQESNLSGRKPLIAGS 497
TNT+ A+ V + Y+L A E A + + +E + +AG+
Sbjct: 71 ATNTFGATD---------IVLDDYDLGYKAEELNICAVKIAKRVAEEFSTPDWPRFVAGA 121
Query: 498 VGPYGAYLHDTSEYTGNYADNTTKETIKNWHRTRIQALVEAGVDILAFETIPCQKEAEA 674
+GP L T T E + +R + L++ G DIL ET + +A
Sbjct: 122 MGPTTKSLSVTG--------GATFEQLIESYRQQATGLIKGGADILLLETSQDMRNVKA 172
>UniRef50_Q67LG1 Cluster: 5-methyltetrahydrofolate S-homocysteine
methyltransferase; n=2; Firmicutes|Rep:
5-methyltetrahydrofolate S-homocysteine
methyltransferase - Symbiobacterium thermophilum
Length = 859
Score = 41.1 bits (92), Expect = 0.027
Identities = 47/186 (25%), Positives = 75/186 (40%)
Frame = +3
Query: 141 EVSSKTVFVLDGGFSTQLTCHAGHTADGDPLWSARFLKTHPQDVINTHLDFLRAGSDIIE 320
++ + V V DG T L +W+ P+DVI H ++ AG+ I+E
Sbjct: 5 DMLGREVLVFDGAMGTMLQAQGLAPGACPDVWNLE----RPEDVIAVHRAYVEAGAQILE 60
Query: 321 TNTYQASVDGFVKHLNLTVEESYELIKSAVEFARTARDLYLQECQESNLSGRKPLIAGSV 500
TNT+ S + H L + +++ + V AR A +GR +AGS+
Sbjct: 61 TNTF-GSTPIRLGHYGLQ-DRCRDIVVAGVRCAREA------------AAGR-AWVAGSM 105
Query: 501 GPYGAYLHDTSEYTGNYADNTTKETIKNWHRTRIQALVEAGVDILAFETIPCQKEAEALV 680
GP GA + E + A + +A EA D + ETI E A V
Sbjct: 106 GPLGALVEPLGELPFDEA--------YAQFAVQARAFAEAQPDFIIIETIADLNELRAAV 157
Query: 681 EILKEY 698
+++
Sbjct: 158 LACRDH 163
>UniRef50_Q2LQ11 Cluster: Methylenetetrahydrofolate reductase; n=1;
Syntrophus aciditrophicus SB|Rep:
Methylenetetrahydrofolate reductase - Syntrophus
aciditrophicus (strain SB)
Length = 618
Score = 40.3 bits (90), Expect = 0.048
Identities = 37/147 (25%), Positives = 60/147 (40%)
Frame = +3
Query: 255 THPQDVINTHLDFLRAGSDIIETNTYQASVDGFVKHLNLTVEESYELIKSAVEFARTARD 434
T P ++ H + +AG+ ++ETN++ A N +Y L + + R A
Sbjct: 43 TEPGLILGIHEQYAQAGAQVLETNSFGA---------NRIKLRAYGLAEKVADINRAAAR 93
Query: 435 LYLQECQESNLSGRKPLIAGSVGPYGAYLHDTSEYTGNYADNTTKETIKNWHRTRIQALV 614
L Q +G +AGSVGP G ++ R +++AL
Sbjct: 94 LARQ------AAGTTLYVAGSVGP--------CTQGGQVITGRDMAEVEAAFREQMEALT 139
Query: 615 EAGVDILAFETIPCQKEAEALVEILKE 695
E GVD+L ET KE + + +E
Sbjct: 140 EEGVDLLLLETFSDLKELQLAARVARE 166
>UniRef50_Q9KCE2 Cluster: Methylenetetrahydrofolate reductase; n=60;
Bacilli|Rep: Methylenetetrahydrofolate reductase -
Bacillus halodurans
Length = 618
Score = 39.5 bits (88), Expect = 0.084
Identities = 19/58 (32%), Positives = 35/58 (60%)
Frame = +3
Query: 255 THPQDVINTHLDFLRAGSDIIETNTYQASVDGFVKHLNLTVEESYELIKSAVEFARTA 428
T P+ ++ H+ ++ AG+D+I+TNTY A+ K+ ++ E+ ++AV AR A
Sbjct: 38 TDPEKIVAAHVAYVEAGADVIQTNTYAANRMKLAKY--QLDDQVLEINRAAVRLARKA 93
>UniRef50_Q5FP86 Cluster: 5-Methyltetrahydrofolate-S-homocysteine
methyltransferase; n=9; cellular organisms|Rep:
5-Methyltetrahydrofolate-S-homocysteine
methyltransferase - Gluconobacter oxydans (Gluconobacter
suboxydans)
Length = 1168
Score = 39.5 bits (88), Expect = 0.084
Identities = 41/146 (28%), Positives = 65/146 (44%)
Frame = +3
Query: 255 THPQDVINTHLDFLRAGSDIIETNTYQASVDGFVKHLNLTVEESYELIKSAVEFARTARD 434
+ P+ V H + AG+D++ETNT+ S+ +T+ E + L E RTA
Sbjct: 50 SRPELVREIHRGYFEAGADMVETNTFGGSI--------VTLAE-FGLQDRTREINRTAAT 100
Query: 435 LYLQECQESNLSGRKPLIAGSVGPYGAYLHDTSEYTGNYADNTTKETIKNWHRTRIQALV 614
L +E E+ GR + GS+GP G L GN A + + + + + L+
Sbjct: 101 L-AREAAETFADGRHRYVMGSIGP-GTKL----PTLGNIAYDDLEAGLVE----QCRGLI 150
Query: 615 EAGVDILAFETIPCQKEAEALVEILK 692
+ GVD ET + +A V K
Sbjct: 151 DGGVDGFLIETCQDTLQIKAAVNAAK 176
>UniRef50_Q18RA6 Cluster: Homocysteine S-methyltransferase; n=2;
Desulfitobacterium hafniense|Rep: Homocysteine
S-methyltransferase - Desulfitobacterium hafniense
(strain DCB-2)
Length = 285
Score = 39.5 bits (88), Expect = 0.084
Identities = 48/189 (25%), Positives = 79/189 (41%), Gaps = 1/189 (0%)
Frame = +3
Query: 165 VLDGGFSTQLTCHAGHTADGDPLWSARFLKTHPQDVINTHLDFLRAGSDIIETNTYQASV 344
+ DG T L + A G P T P+ + H +++AGS+II TNT+ A
Sbjct: 10 IFDGAMGTMLQKY--DLAPGQPPEVLNI--TRPEVIEEVHRKYIKAGSNIITTNTFGA-- 63
Query: 345 DGFVKHLNLTVEESYELIKSAVEFARTARDLYLQECQESNLSGRKPLIAGSVGPYGAYLH 524
LN T E+++SA+ AR A K L+A VGP G +
Sbjct: 64 --IETKLNGTGYSVEEVVQSAIAIARRA--------------AGKNLVALDVGPTGELIE 107
Query: 525 DTSEYTGNYADNTTKETIKNWHRTRIQALVEAG-VDILAFETIPCQKEAEALVEILKEYP 701
+ + E + + + +I+A G VD++ ET EA A + K++
Sbjct: 108 PLGD--------LSFEEVYDLYACQIKAAALTGNVDLVLIETFFDLTEAHAAIRAAKDHS 159
Query: 702 NMKAWLSFS 728
++ +F+
Sbjct: 160 SLPVICTFT 168
>UniRef50_A7C1C8 Cluster: 5-methyltetrahydrofolate--homocysteine
S-methyltransferase; n=1; Beggiatoa sp. PS|Rep:
5-methyltetrahydrofolate--homocysteine
S-methyltransferase - Beggiatoa sp. PS
Length = 157
Score = 39.5 bits (88), Expect = 0.084
Identities = 25/71 (35%), Positives = 38/71 (53%), Gaps = 1/71 (1%)
Frame = +3
Query: 255 THPQDVINTHLDFLRAGSDIIETNTYQASVDGFVKHLNLTVEE-SYELIKSAVEFARTAR 431
T P + H +L AG+DIIETNT+ A+ + + +EE YEL + + AR A
Sbjct: 58 TQPHIIKEIHTQYLEAGADIIETNTFNAT---RIAMADYRMEELVYELNVAGAKLAREAA 114
Query: 432 DLYLQECQESN 464
D Q+ Q ++
Sbjct: 115 DEMAQKHQTNH 125
>UniRef50_Q5UEY6 Cluster: Putative homocysteine S-methyltransferase
family protein; n=1; uncultured alpha proteobacterium
EBAC2C11|Rep: Putative homocysteine S-methyltransferase
family protein - uncultured alpha proteobacterium
EBAC2C11
Length = 309
Score = 39.1 bits (87), Expect = 0.11
Identities = 19/59 (32%), Positives = 31/59 (52%)
Frame = +3
Query: 165 VLDGGFSTQLTCHAGHTADGDPLWSARFLKTHPQDVINTHLDFLRAGSDIIETNTYQAS 341
+LD G ST+L +G WS + ++ TH+ ++ AG+DII N+Y +S
Sbjct: 19 ILDSGVSTELERRGAKMRNGQ--WSGCVAIDDYEKLVETHIAYIEAGADIITVNSYASS 75
>UniRef50_A6Q2F4 Cluster: 5-methyltetrahydrofolate--homocysteine
methyltransferase; n=2; Epsilonproteobacteria|Rep:
5-methyltetrahydrofolate--homocysteine methyltransferase
- Nitratiruptor sp. (strain SB155-2)
Length = 1148
Score = 39.1 bits (87), Expect = 0.11
Identities = 25/98 (25%), Positives = 47/98 (47%), Gaps = 4/98 (4%)
Frame = +3
Query: 159 VFVLDGGFSTQLTCHAGHTA----DGDPLWSARFLKTHPQDVINTHLDFLRAGSDIIETN 326
+ ++DG TQL A + +G + +T P+ + + H + + G+DII+TN
Sbjct: 10 ILIIDGAMGTQLQAKANEISADVWEGKEGCNELLNRTAPKVIKSIHEAYAKVGADIIKTN 69
Query: 327 TYQASVDGFVKHLNLTVEESYELIKSAVEFARTARDLY 440
T+ S+ + +L E+Y+L K E + + Y
Sbjct: 70 TF-GSMPWVLDEYDL-ASEAYDLTKRGCELVKEVCETY 105
>UniRef50_Q4V9Q6 Cluster: Apolipoprotein A-IV; n=11;
Clupeocephala|Rep: Apolipoprotein A-IV - Danio rerio
(Zebrafish) (Brachydanio rerio)
Length = 403
Score = 38.7 bits (86), Expect = 0.15
Identities = 20/58 (34%), Positives = 32/58 (55%)
Frame = +3
Query: 249 LKTHPQDVINTHLDFLRAGSDIIETNTYQASVDGFVKHLNLTVEESYELIKSAVEFAR 422
L HP+ V H +FLRAGS++++T T+ AS D N ++ ++A + AR
Sbjct: 75 LAEHPEAVRQLHREFLRAGSNVMQTFTFYASDDKLENRGNKLSFTGQQINEAACDLAR 132
>UniRef50_Q22HI1 Cluster: Homocysteine S-methyltransferase family
protein; n=1; Tetrahymena thermophila SB210|Rep:
Homocysteine S-methyltransferase family protein -
Tetrahymena thermophila SB210
Length = 600
Score = 37.9 bits (84), Expect = 0.26
Identities = 19/69 (27%), Positives = 40/69 (57%)
Frame = +3
Query: 234 WSARFLKTHPQDVINTHLDFLRAGSDIIETNTYQASVDGFVKHLNLTVEESYELIKSAVE 413
W R LK P+ + + HL++ + G+DII + T++ + ++EES +L++ AV+
Sbjct: 29 WMNRILKEKPEKLYDLHLEYCKQGADIITSFTFKTNPIAC-----QSLEESKKLVQIAVK 83
Query: 414 FARTARDLY 440
+ +++Y
Sbjct: 84 ECQKLKEIY 92
>UniRef50_A0RW49 Cluster: Methionine synthase I
(Cobalamin-dependent), methyltransferase domain; n=1;
Cenarchaeum symbiosum|Rep: Methionine synthase I
(Cobalamin-dependent), methyltransferase domain -
Cenarchaeum symbiosum
Length = 317
Score = 37.9 bits (84), Expect = 0.26
Identities = 42/184 (22%), Positives = 76/184 (41%), Gaps = 3/184 (1%)
Frame = +3
Query: 141 EVSSKTVFVLDGGFSTQLTC---HAGHTADGDPLWSARFLKTHPQDVINTHLDFLRAGSD 311
E + V + DG T++ DG ++ + + P+ + H ++ AG+D
Sbjct: 9 EAARGRVLLFDGAMGTEIQALDPGPEDFPDGKEGFNDGLVLSRPEWISKIHRSYIEAGAD 68
Query: 312 IIETNTYQASVDGFVKHLNLTVEESYELIKSAVEFARTARDLYLQECQESNLSGRKPLIA 491
IETN++ ++ + ++E Y + VE A L E+ R +
Sbjct: 69 CIETNSFGSN--------KIKLDE-YGFGERTVEINEKAASL---AAAEAGRVERDVYVV 116
Query: 492 GSVGPYGAYLHDTSEYTGNYADNTTKETIKNWHRTRIQALVEAGVDILAFETIPCQKEAE 671
GS+GP G YL +++ +TI++ + + LV G D L ET E +
Sbjct: 117 GSMGPTG-YLPSSNDPD---LGQIPLDTIQDAFALQAEGLVRGGADALIIETSQDILEVK 172
Query: 672 ALVE 683
+E
Sbjct: 173 LAIE 176
>UniRef50_Q9WYU7 Cluster: Putative uncharacterized protein; n=2;
Thermotoga|Rep: Putative uncharacterized protein -
Thermotoga maritima
Length = 417
Score = 37.5 bits (83), Expect = 0.34
Identities = 29/90 (32%), Positives = 42/90 (46%), Gaps = 3/90 (3%)
Frame = +3
Query: 279 THLDFLRAG--SDIIETNTYQA-SVDGFVKHLNLTVEESYELIKSAVEFARTARDLYLQE 449
T+LD L A +T+T A S G+ HLNLT ++ E + + +A A +YL E
Sbjct: 167 TNLDLLDATLFGAFYDTDTNNATSAYGYAAHLNLTGKDILENLVVDLAYAYEATSMYLVE 226
Query: 450 CQESNLSGRKPLIAGSVGPYGAYLHDTSEY 539
Q S +P + +V PY Y Y
Sbjct: 227 AQYSKSFEMEP-VTLTVSPYFVYSEGAPTY 255
>UniRef50_Q20HV9 Cluster: Msh; n=2; Agrobacterium tumefaciens|Rep:
Msh - Agrobacterium tumefaciens
Length = 316
Score = 37.1 bits (82), Expect = 0.45
Identities = 22/61 (36%), Positives = 31/61 (50%)
Frame = +3
Query: 150 SKTVFVLDGGFSTQLTCHAGHTADGDPLWSARFLKTHPQDVINTHLDFLRAGSDIIETNT 329
S V +LDGG +L + P WSA L P+ V H F+ AG+++I TN+
Sbjct: 2 SSKVTILDGGMGRELLRNGAPFRQ--PEWSALSLIEAPEFVKMAHDAFVAAGAEVITTNS 59
Query: 330 Y 332
Y
Sbjct: 60 Y 60
>UniRef50_A4EBI1 Cluster: Putative uncharacterized protein; n=1;
Collinsella aerofaciens ATCC 25986|Rep: Putative
uncharacterized protein - Collinsella aerofaciens ATCC
25986
Length = 297
Score = 37.1 bits (82), Expect = 0.45
Identities = 40/132 (30%), Positives = 60/132 (45%), Gaps = 2/132 (1%)
Frame = +3
Query: 261 PQDVINTHLDFLRAGSDIIETNTYQASVDGFVKHLNLTVEESYELIKSAVEFARTARDLY 440
PQ V H ++ AG+ ++ TNT+QAS +KH + + E+ + AV+ AR A
Sbjct: 52 PQTVSRIHRLYVAAGAQVLITNTFQAS-SYALKHDQIAPSVA-EVNRGAVDDARQA---- 105
Query: 441 LQECQESNLSGRKPLIAGSVGPYGA--YLHDTSEYTGNYADNTTKETIKNWHRTRIQALV 614
L+ GS+GP G + D+ EY I+ R + AL+
Sbjct: 106 -----------HPQLLLGSMGPIGIEWFAEDSVEY----------REIRGIAREQAHALL 144
Query: 615 EAGVDILAFETI 650
AGVD L ET+
Sbjct: 145 NAGVDGLLIETV 156
>UniRef50_Q194H8 Cluster: TRNA-i(6)A37 thiotransferase enzyme MiaB;
n=4; Clostridia|Rep: TRNA-i(6)A37 thiotransferase enzyme
MiaB - Desulfitobacterium hafniense (strain DCB-2)
Length = 447
Score = 36.7 bits (81), Expect = 0.59
Identities = 19/63 (30%), Positives = 33/63 (52%), Gaps = 2/63 (3%)
Frame = +3
Query: 225 DPLWSARFLKTHPQDVINTHLDFLRAGSDIIE--TNTYQASVDGFVKHLNLTVEESYELI 398
D LW RF+ +HP+D+ + ++ + AG+ + E +QA D +K +N Y L
Sbjct: 232 DGLWRVRFMTSHPKDLSDKLIETIAAGTHLCEHIHLPFQAGSDEILKGMNRKYTREYYLS 291
Query: 399 KSA 407
+ A
Sbjct: 292 RIA 294
>UniRef50_Q8ESE8 Cluster: Betaine-homocysteine methyltransferase;
n=5; Bacteria|Rep: Betaine-homocysteine
methyltransferase - Oceanobacillus iheyensis
Length = 349
Score = 36.3 bits (80), Expect = 0.78
Identities = 42/148 (28%), Positives = 69/148 (46%), Gaps = 2/148 (1%)
Frame = +3
Query: 258 HPQDVINTHLDFLRAGSDIIETNTYQASVDGFVKHLNLTVEESYE-LIKSAVEFARTARD 434
+P + T+ DF+ AGSD++ TY A + K + E+ E L +SA+ A+
Sbjct: 43 NPDALKQTYRDFMNAGSDVVLAFTYNAHRE---KMRIIGKEQLLEPLNRSAIRLAKEVAK 99
Query: 435 LYLQECQESNLSGRKPLIAGSVGPYGAYLHDTSEYTGNYADNTTKETIKNWHRTRIQALV 614
+ QE + L+AG++ +T+ + N D ++K ++ Q
Sbjct: 100 EHPQE---------EALVAGNIS-------NTNIFDPN--DESSKHKVREMFAEMAQWSK 141
Query: 615 EAGVDILAFETIPCQKEAE-ALVEILKE 695
E VD + ET +EAE AL EILK+
Sbjct: 142 EEDVDFINGETFYYHEEAEIALEEILKK 169
>UniRef50_A5DLU3 Cluster: Putative uncharacterized protein; n=1;
Pichia guilliermondii|Rep: Putative uncharacterized
protein - Pichia guilliermondii (Yeast) (Candida
guilliermondii)
Length = 769
Score = 35.9 bits (79), Expect = 1.0
Identities = 24/76 (31%), Positives = 35/76 (46%), Gaps = 7/76 (9%)
Frame = +3
Query: 375 VEESYELIKSAV-EFARTARDLYLQECQESN------LSGRKPLIAGSVGPYGAYLHDTS 533
+EES + A EFA + L Q+ +ES L K L+AG++G +D
Sbjct: 530 IEESASSVALAANEFATSLSKLLKQKSKESQQAANLYLDSAKKLVAGTIGKLTGQANDLQ 589
Query: 534 EYTGNYADNTTKETIK 581
+ G YAD +K K
Sbjct: 590 DVAGKYADQASKSAEK 605
>UniRef50_A4EKV4 Cluster: Methionine synthase I; n=5;
Proteobacteria|Rep: Methionine synthase I - Roseobacter
sp. CCS2
Length = 339
Score = 35.1 bits (77), Expect = 1.8
Identities = 47/185 (25%), Positives = 71/185 (38%)
Frame = +3
Query: 129 MSNFEVSSKTVFVLDGGFSTQLTCHAGHTADGDPLWSARFLKTHPQDVINTHLDFLRAGS 308
+SN + ++ + DG T L + D +W+ +I + AGS
Sbjct: 6 LSNL-LKTRDWLMADGATGTNLFNMGLMSGDAPEMWNV----DETAKIIALYKGAADAGS 60
Query: 309 DIIETNTYQASVDGFVKHLNLTVEESYELIKSAVEFARTARDLYLQECQESNLSGRKPLI 488
DI TN++ A+ H EL K+A E R D S R ++
Sbjct: 61 DIFLTNSFGANASRLKLHG--AEGRVKELNKAAAELGREVADA----------SERVIVV 108
Query: 489 AGSVGPYGAYLHDTSEYTGNYADNTTKETIKNWHRTRIQALVEAGVDILAFETIPCQKEA 668
AGSVGP G + T A ++ +H + + L G D+L ETI +E
Sbjct: 109 AGSVGPTGEIMAPMGSLTHEIA-------VEMFHE-QAEGLKAGGADVLWVETISAPEEF 160
Query: 669 EALVE 683
A E
Sbjct: 161 AAASE 165
>UniRef50_A1SNY1 Cluster: Metallophosphoesterase; n=1; Nocardioides
sp. JS614|Rep: Metallophosphoesterase - Nocardioides sp.
(strain BAA-499 / JS614)
Length = 480
Score = 35.1 bits (77), Expect = 1.8
Identities = 22/88 (25%), Positives = 43/88 (48%), Gaps = 1/88 (1%)
Frame = +3
Query: 267 DVINTHLDFLRAGSDIIETNTYQASVDGFVKHLNLTVEESYELIKSAVEFARTARDLYLQ 446
D+ + H D++ G + DG ++T +++ LI+SAV+ T++D Y Q
Sbjct: 140 DIEDVHRDWIPLGEFLGSGVPLPDEADGVEVSGDVTTKQTRRLIESAVDTYNTSKDFYAQ 199
Query: 447 ECQE-SNLSGRKPLIAGSVGPYGAYLHD 527
++ + L R P+ +V + + HD
Sbjct: 200 AAEDAARLGLRHPVEGDTVVAFVSDRHD 227
>UniRef50_A5K8K1 Cluster: Putative uncharacterized protein; n=1;
Plasmodium vivax|Rep: Putative uncharacterized protein -
Plasmodium vivax
Length = 508
Score = 35.1 bits (77), Expect = 1.8
Identities = 23/93 (24%), Positives = 44/93 (47%)
Frame = +3
Query: 150 SKTVFVLDGGFSTQLTCHAGHTADGDPLWSARFLKTHPQDVINTHLDFLRAGSDIIETNT 329
+K VF LDGG ++L D + + N HL +L AG ++I TNT
Sbjct: 2 AKEVFTLDGGKISELERLGVGNFDFLSCHDEGDEEQMVSTLENIHLSYLLAGCNVISTNT 61
Query: 330 YQASVDGFVKHLNLTVEESYELIKSAVEFARTA 428
+Q ++ ++ ++V++ ++ ++ A A
Sbjct: 62 FQVNLHS-LQEKGISVQDGEGIVDRYIDIAHRA 93
>UniRef50_A5FRS2 Cluster: SMC domain protein; n=3;
Dehalococcoides|Rep: SMC domain protein -
Dehalococcoides sp. BAV1
Length = 859
Score = 34.7 bits (76), Expect = 2.4
Identities = 35/122 (28%), Positives = 53/122 (43%), Gaps = 2/122 (1%)
Frame = +3
Query: 309 DIIETNTYQASVDGFVKHLNL--TVEESYELIKSAVEFARTARDLYLQECQESNLSGRKP 482
D +E QA + K+L + ++E+ E +KS E A + Q+ E +
Sbjct: 175 DQLEDLARQAVREAETKNLQIEQSIEDGKESLKSRPELEE-ALNHTRQDLAEGEGKLKIQ 233
Query: 483 LIAGSVGPYGAYLHDTSEYTGNYADNTTKETIKNWHRTRIQALVEAGVDILAFETIPCQK 662
L + + + DT + T DN K+ K+ R IQ L E I FET+ QK
Sbjct: 234 LAELEIMRHKKHSFDTKQNTCRQLDNDLKDISKDQSRW-IQTLQEIKQRISTFETLSAQK 292
Query: 663 EA 668
EA
Sbjct: 293 EA 294
>UniRef50_O34073 Cluster: ORF42; n=2; unclassified Siphoviridae|Rep:
ORF42 - Streptococcus phage O1205
Length = 1006
Score = 34.7 bits (76), Expect = 2.4
Identities = 19/72 (26%), Positives = 36/72 (50%)
Frame = +3
Query: 519 LHDTSEYTGNYADNTTKETIKNWHRTRIQALVEAGVDILAFETIPCQKEAEALVEILKEY 698
+HD + Y DN + T+ N+ + +E+G + F ++++ VEI +Y
Sbjct: 5 IHDNNLQKVAYIDNEKQSTL-NFFNDKWTRSLESGTSVFEFSVFKKSIKSDSKVEIAYKY 63
Query: 699 PNMKAWLSFSCK 734
N +A++SF K
Sbjct: 64 LNERAFVSFKHK 75
>UniRef50_P47723 Cluster: Phosphomannomutase; n=1; Mycoplasma
pirum|Rep: Phosphomannomutase - Mycoplasma pirum
Length = 544
Score = 34.7 bits (76), Expect = 2.4
Identities = 32/116 (27%), Positives = 50/116 (43%), Gaps = 3/116 (2%)
Frame = +3
Query: 243 RFLKTHPQDVINTHLDFLRAGSDIIETNTYQASVDGF---VKHLNLTVEESYELIKSAVE 413
R +K + +V F G I + + V GF V LN T+ K A +
Sbjct: 353 RIIKEYHGEVYRVGTGFKWVGDKINKIKDSEEFVVGFEEAVGALNSTINRD----KDAYQ 408
Query: 414 FARTARDLYLQECQESNLSGRKPLIAGSVGPYGAYLHDTSEYTGNYADNTTKETIK 581
A A ++Y EC ++N++ L G YG +DT +T + +N KE +K
Sbjct: 409 AAALALEIY-NECLKNNINIIDHLEKNIYGKYGIIHNDTISFT--FVENNWKELVK 461
>UniRef50_A5TSJ3 Cluster: Putative uncharacterized protein; n=1;
Fusobacterium nucleatum subsp. polymorphum ATCC
10953|Rep: Putative uncharacterized protein -
Fusobacterium nucleatum subsp. polymorphum ATCC 10953
Length = 313
Score = 34.3 bits (75), Expect = 3.1
Identities = 29/106 (27%), Positives = 44/106 (41%), Gaps = 6/106 (5%)
Frame = +3
Query: 435 LYLQECQESNLSGRKPLIAGSVGPYGAYLHDT--SEYTGNYADNTTKETIKNWHRTRIQA 608
LY E S P+I + +GAY D SEY KE IKN+ I++
Sbjct: 10 LYRNELNFSEAFCTVPIIMDKIMIWGAYDVDLNMSEYIWCQLPEKFKEKIKNYKGYTIKS 69
Query: 609 LVEAGVDILAFETIPCQ----KEAEALVEILKEYPNMKAWLSFSCK 734
++ DI A+ K+ + E+ +++ K FSCK
Sbjct: 70 MIITVTDITAYSVSISNHEKLKDTITMEEVYEDFSKNKKIEKFSCK 115
>UniRef50_Q4HKG9 Cluster: Flagellar hook-associated protein 2
(FliD), putative; n=1; Campylobacter lari RM2100|Rep:
Flagellar hook-associated protein 2 (FliD), putative -
Campylobacter lari RM2100
Length = 766
Score = 33.5 bits (73), Expect = 5.5
Identities = 23/78 (29%), Positives = 38/78 (48%), Gaps = 1/78 (1%)
Frame = +3
Query: 504 PYGAYLHDTSEYTGNYADNTTKETIKNWHRTRIQALVEAGVDILAFE-TIPCQKEAEALV 680
P GA + + TG+ + NTT + + + +T + +++ G F I Q E+L
Sbjct: 236 PTGAGEENKDKITGSISGNTTDKLLNSGEKTSLTFVIKNGERYDRFTIDINDQTTYESLA 295
Query: 681 EILKEYPNMKAWLSFSCK 734
E LK+ N K LSF +
Sbjct: 296 EDLKKQTNGKVELSFGAE 313
>UniRef50_A6CG77 Cluster: Polyhydroxyalkanoate synthesis repressor
PhaR; n=1; Planctomyces maris DSM 8797|Rep:
Polyhydroxyalkanoate synthesis repressor PhaR -
Planctomyces maris DSM 8797
Length = 2475
Score = 33.5 bits (73), Expect = 5.5
Identities = 24/74 (32%), Positives = 37/74 (50%), Gaps = 4/74 (5%)
Frame = +3
Query: 105 INLFFYEIMS--NFEVSSKTVFVLDG--GFSTQLTCHAGHTADGDPLWSARFLKTHPQDV 272
++L FY+ + + EV + T V+DG G Q + + DP SA T +DV
Sbjct: 647 VDLSFYQDLDAGDTEVITYTYNVIDGLGGSVAQTVTITINGQNDDPTISAAVTSTVSEDV 706
Query: 273 INTHLDFLRAGSDI 314
+N +LD L SD+
Sbjct: 707 VNFNLDLLTNASDV 720
>UniRef50_A4J1H2 Cluster: Putative uncharacterized protein; n=2;
Desulfotomaculum reducens MI-1|Rep: Putative
uncharacterized protein - Desulfotomaculum reducens MI-1
Length = 679
Score = 33.5 bits (73), Expect = 5.5
Identities = 15/48 (31%), Positives = 26/48 (54%)
Frame = -1
Query: 184 ENPPSNTKTVFEDTSKFDIIS*KNKFIVRKLLQHTYRIFYNNLIRCNY 41
ENPP+N K V ++ I ++ +++ L H + +F NN C+Y
Sbjct: 245 ENPPANDKKVKDNNYNIKAIKNRDIKYLKEKLNHPHMVFNNNQEFCDY 292
>UniRef50_A3JU33 Cluster: Homocysteine S-methyltransferase; n=1;
Rhodobacterales bacterium HTCC2150|Rep: Homocysteine
S-methyltransferase - Rhodobacterales bacterium HTCC2150
Length = 314
Score = 33.5 bits (73), Expect = 5.5
Identities = 22/79 (27%), Positives = 39/79 (49%)
Frame = +3
Query: 432 DLYLQECQESNLSGRKPLIAGSVGPYGAYLHDTSEYTGNYADNTTKETIKNWHRTRIQAL 611
DLY + +++L+ + +I+G +GP G Y N N ++ + +H +I+
Sbjct: 103 DLYRECATKASLTAQNTIISGCIGPKG------DAYQTNKTLNA--QSAEAYHAEQIETF 154
Query: 612 VEAGVDILAFETIPCQKEA 668
AGVDI+ T+ EA
Sbjct: 155 KNAGVDIITALTLNTTDEA 173
>UniRef50_Q8JKN6 Cluster: Orf76; n=1; Heliothis zea virus 1|Rep:
Orf76 - Heliothis zea virus 1
Length = 442
Score = 33.1 bits (72), Expect = 7.3
Identities = 17/51 (33%), Positives = 28/51 (54%)
Frame = -2
Query: 270 HLEGVSLKIVHSKEDRHQQYDRRDRSTVLRILHPTQRLSLKILQNSTLFHK 118
HL+ L ++H+ D + +R+ ++VL + PT I+QN TLF K
Sbjct: 222 HLDNPVLYLLHTINDPSAEMERQSLTSVLGGVTPTMETFETIVQNDTLFAK 272
>UniRef50_Q93HC9 Cluster: Putative hydrolase; n=1; Streptomyces
avermitilis|Rep: Putative hydrolase - Streptomyces
avermitilis
Length = 241
Score = 32.7 bits (71), Expect = 9.6
Identities = 16/42 (38%), Positives = 25/42 (59%)
Frame = +3
Query: 213 TADGDPLWSARFLKTHPQDVINTHLDFLRAGSDIIETNTYQA 338
+ADGDP WS L+ P D + LD + G+D+I +++ A
Sbjct: 5 SADGDPDWS---LRDDPADHVEHALDSVPGGADVIVVHSFTA 43
>UniRef50_A1DNS1 Cluster: C2H2 type zinc finger domain protein; n=2;
Trichocomaceae|Rep: C2H2 type zinc finger domain protein
- Neosartorya fischeri (strain ATCC 1020 / DSM 3700 /
NRRL 181)(Aspergillus fischerianus (strain ATCC 1020 /
DSM 3700 / NRRL 181))
Length = 745
Score = 32.7 bits (71), Expect = 9.6
Identities = 25/72 (34%), Positives = 36/72 (50%), Gaps = 4/72 (5%)
Frame = +3
Query: 327 TYQASVDGFVKHLNLTVEESYELIKSAVEFARTARDLYLQECQESNL--SGRKPLI--AG 494
++ SV+ + L L V ++ KSA EFA AR + + C+ L KPL+ AG
Sbjct: 394 SFLRSVENILTLLFLCVSGAWSGHKSAFEFAEGARGILVTACRRCRLLDCRPKPLVTDAG 453
Query: 495 SVGPYGAYLHDT 530
+ P A L DT
Sbjct: 454 ATRPMRAKLLDT 465
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 703,580,306
Number of Sequences: 1657284
Number of extensions: 14599934
Number of successful extensions: 41034
Number of sequences better than 10.0: 138
Number of HSP's better than 10.0 without gapping: 39191
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 40904
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 59677054775
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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