Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= bmnc22p14
(736 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
U75743-1|AAB58906.1| 1265|Homo sapiens methionine synthase protein. 52 3e-06
U73338-1|AAB39704.1| 1265|Homo sapiens methionine synthase protein. 52 3e-06
U71285-1|AAC51188.1| 1265|Homo sapiens 5-methyltetrahydrofolate-... 52 3e-06
BC130616-1|AAI30617.1| 1265|Homo sapiens 5-methyltetrahydrofolat... 52 3e-06
AL359259-1|CAH70983.1| 1265|Homo sapiens 5-methyltetrahydrofolat... 52 3e-06
AL359185-1|CAH73198.1| 1265|Homo sapiens 5-methyltetrahydrofolat... 52 3e-06
U50929-1|AAC50668.1| 406|Homo sapiens betaine:homocysteine meth... 46 1e-04
BC012616-1|AAH12616.1| 406|Homo sapiens betaine-homocysteine me... 46 1e-04
AF118378-1|AAD22043.1| 406|Homo sapiens betaine-homocysteine me... 46 1e-04
BC020665-1|AAH20665.1| 363|Homo sapiens betaine-homocysteine me... 44 6e-04
AF257473-1|AAG41356.1| 363|Homo sapiens betaine-homocysteine me... 44 6e-04
AF061324-1|AAC16058.1| 1549|Homo sapiens sulfonylurea receptor 2... 32 2.5
AF061323-1|AAC16057.1| 1549|Homo sapiens sulfonylurea receptor 2... 32 2.5
>U75743-1|AAB58906.1| 1265|Homo sapiens methionine synthase protein.
Length = 1265
Score = 51.6 bits (118), Expect = 3e-06
Identities = 56/199 (28%), Positives = 89/199 (44%), Gaps = 16/199 (8%)
Frame = +3
Query: 144 VSSKTVFVLDGGFSTQLT---CHAGHTADGDPLWSARFLK--------THPQDVINTHLD 290
+ K + VLDGG T + + H + AR LK T P + H +
Sbjct: 25 ILQKRIMVLDGGMGTMIQREKLNEEHFRGQEFKDHARPLKGNNDILSITQPDVIYQIHKE 84
Query: 291 FLRAGSDIIETNTYQ----ASVDGFVKHLNLTVEESYELIKSAVEFAR-TARDLYLQECQ 455
+L AG+DIIETNT+ A D ++HL +Y + + AR A ++ LQ
Sbjct: 85 YLLAGADIIETNTFSSTSIAQADYGLEHL------AYRMNMCSAGVARKAAEEVTLQ--- 135
Query: 456 ESNLSGRKPLIAGSVGPYGAYLHDTSEYTGNYADNTTKETIKNWHRTRIQALVEAGVDIL 635
+G K +AG++GP L + N T + + ++ + + L++ GVDIL
Sbjct: 136 ----TGIKRFVAGALGPTNKTLSVSPSVERPDYRNITFDELVEAYQEQAKGLLDGGVDIL 191
Query: 636 AFETIPCQKEAEALVEILK 692
ETI A+A + L+
Sbjct: 192 LIETIFDTANAKAALFALQ 210
>U73338-1|AAB39704.1| 1265|Homo sapiens methionine synthase protein.
Length = 1265
Score = 51.6 bits (118), Expect = 3e-06
Identities = 56/199 (28%), Positives = 89/199 (44%), Gaps = 16/199 (8%)
Frame = +3
Query: 144 VSSKTVFVLDGGFSTQLT---CHAGHTADGDPLWSARFLK--------THPQDVINTHLD 290
+ K + VLDGG T + + H + AR LK T P + H +
Sbjct: 25 ILQKRIMVLDGGMGTMIQREKLNEEHFRGQEFKDHARPLKGNNDILSITQPDVIYQIHKE 84
Query: 291 FLRAGSDIIETNTYQ----ASVDGFVKHLNLTVEESYELIKSAVEFAR-TARDLYLQECQ 455
+L AG+DIIETNT+ A D ++HL +Y + + AR A ++ LQ
Sbjct: 85 YLLAGADIIETNTFSSTSIAQADYGLEHL------AYRMNMCSAGVARKAAEEVTLQ--- 135
Query: 456 ESNLSGRKPLIAGSVGPYGAYLHDTSEYTGNYADNTTKETIKNWHRTRIQALVEAGVDIL 635
+G K +AG++GP L + N T + + ++ + + L++ GVDIL
Sbjct: 136 ----TGIKRFVAGALGPTNKTLSVSPSVERPDYRNITFDELVEAYQEQAKGLLDGGVDIL 191
Query: 636 AFETIPCQKEAEALVEILK 692
ETI A+A + L+
Sbjct: 192 LIETIFDTANAKAALFALQ 210
>U71285-1|AAC51188.1| 1265|Homo sapiens
5-methyltetrahydrofolate-homocysteine methyltransferase
protein.
Length = 1265
Score = 51.6 bits (118), Expect = 3e-06
Identities = 56/199 (28%), Positives = 89/199 (44%), Gaps = 16/199 (8%)
Frame = +3
Query: 144 VSSKTVFVLDGGFSTQLT---CHAGHTADGDPLWSARFLK--------THPQDVINTHLD 290
+ K + VLDGG T + + H + AR LK T P + H +
Sbjct: 25 ILQKRIMVLDGGMGTMIQREKLNEEHFRGQEFKDHARPLKGNNDILSITQPDVIYQIHKE 84
Query: 291 FLRAGSDIIETNTYQ----ASVDGFVKHLNLTVEESYELIKSAVEFAR-TARDLYLQECQ 455
+L AG+DIIETNT+ A D ++HL +Y + + AR A ++ LQ
Sbjct: 85 YLLAGADIIETNTFSSTSIAQADYGLEHL------AYRMNMCSAGVARKAAEEVTLQ--- 135
Query: 456 ESNLSGRKPLIAGSVGPYGAYLHDTSEYTGNYADNTTKETIKNWHRTRIQALVEAGVDIL 635
+G K +AG++GP L + N T + + ++ + + L++ GVDIL
Sbjct: 136 ----TGIKRFVAGALGPTNKTLSVSPSVERPDYRNITFDELVEAYQEQAKGLLDGGVDIL 191
Query: 636 AFETIPCQKEAEALVEILK 692
ETI A+A + L+
Sbjct: 192 LIETIFDTANAKAALFALQ 210
>BC130616-1|AAI30617.1| 1265|Homo sapiens
5-methyltetrahydrofolate-homocysteine methyltransferase
protein.
Length = 1265
Score = 51.6 bits (118), Expect = 3e-06
Identities = 56/199 (28%), Positives = 89/199 (44%), Gaps = 16/199 (8%)
Frame = +3
Query: 144 VSSKTVFVLDGGFSTQLT---CHAGHTADGDPLWSARFLK--------THPQDVINTHLD 290
+ K + VLDGG T + + H + AR LK T P + H +
Sbjct: 25 ILQKRIMVLDGGMGTMIQREKLNEEHFRGQEFKDHARPLKGNNDILSITQPDVIYQIHKE 84
Query: 291 FLRAGSDIIETNTYQ----ASVDGFVKHLNLTVEESYELIKSAVEFAR-TARDLYLQECQ 455
+L AG+DIIETNT+ A D ++HL +Y + + AR A ++ LQ
Sbjct: 85 YLLAGADIIETNTFSSTSIAQADYGLEHL------AYRMNMCSAGVARKAAEEVTLQ--- 135
Query: 456 ESNLSGRKPLIAGSVGPYGAYLHDTSEYTGNYADNTTKETIKNWHRTRIQALVEAGVDIL 635
+G K +AG++GP L + N T + + ++ + + L++ GVDIL
Sbjct: 136 ----TGIKRFVAGALGPTNKTLSVSPSVERPDYRNITFDELVEAYQEQAKGLLDGGVDIL 191
Query: 636 AFETIPCQKEAEALVEILK 692
ETI A+A + L+
Sbjct: 192 LIETIFDTANAKAALFALQ 210
>AL359259-1|CAH70983.1| 1265|Homo sapiens
5-methyltetrahydrofolate-homocysteine methyltransferase
protein.
Length = 1265
Score = 51.6 bits (118), Expect = 3e-06
Identities = 56/199 (28%), Positives = 89/199 (44%), Gaps = 16/199 (8%)
Frame = +3
Query: 144 VSSKTVFVLDGGFSTQLT---CHAGHTADGDPLWSARFLK--------THPQDVINTHLD 290
+ K + VLDGG T + + H + AR LK T P + H +
Sbjct: 25 ILQKRIMVLDGGMGTMIQREKLNEEHFRGQEFKDHARPLKGNNDILSITQPDVIYQIHKE 84
Query: 291 FLRAGSDIIETNTYQ----ASVDGFVKHLNLTVEESYELIKSAVEFAR-TARDLYLQECQ 455
+L AG+DIIETNT+ A D ++HL +Y + + AR A ++ LQ
Sbjct: 85 YLLAGADIIETNTFSSTSIAQADYGLEHL------AYRMNMCSAGVARKAAEEVTLQ--- 135
Query: 456 ESNLSGRKPLIAGSVGPYGAYLHDTSEYTGNYADNTTKETIKNWHRTRIQALVEAGVDIL 635
+G K +AG++GP L + N T + + ++ + + L++ GVDIL
Sbjct: 136 ----TGIKRFVAGALGPTNKTLSVSPSVERPDYRNITFDELVEAYQEQAKGLLDGGVDIL 191
Query: 636 AFETIPCQKEAEALVEILK 692
ETI A+A + L+
Sbjct: 192 LIETIFDTANAKAALFALQ 210
>AL359185-1|CAH73198.1| 1265|Homo sapiens
5-methyltetrahydrofolate-homocysteine methyltransferase
protein.
Length = 1265
Score = 51.6 bits (118), Expect = 3e-06
Identities = 56/199 (28%), Positives = 89/199 (44%), Gaps = 16/199 (8%)
Frame = +3
Query: 144 VSSKTVFVLDGGFSTQLT---CHAGHTADGDPLWSARFLK--------THPQDVINTHLD 290
+ K + VLDGG T + + H + AR LK T P + H +
Sbjct: 25 ILQKRIMVLDGGMGTMIQREKLNEEHFRGQEFKDHARPLKGNNDILSITQPDVIYQIHKE 84
Query: 291 FLRAGSDIIETNTYQ----ASVDGFVKHLNLTVEESYELIKSAVEFAR-TARDLYLQECQ 455
+L AG+DIIETNT+ A D ++HL +Y + + AR A ++ LQ
Sbjct: 85 YLLAGADIIETNTFSSTSIAQADYGLEHL------AYRMNMCSAGVARKAAEEVTLQ--- 135
Query: 456 ESNLSGRKPLIAGSVGPYGAYLHDTSEYTGNYADNTTKETIKNWHRTRIQALVEAGVDIL 635
+G K +AG++GP L + N T + + ++ + + L++ GVDIL
Sbjct: 136 ----TGIKRFVAGALGPTNKTLSVSPSVERPDYRNITFDELVEAYQEQAKGLLDGGVDIL 191
Query: 636 AFETIPCQKEAEALVEILK 692
ETI A+A + L+
Sbjct: 192 LIETIFDTANAKAALFALQ 210
>U50929-1|AAC50668.1| 406|Homo sapiens betaine:homocysteine
methyltransferase protein.
Length = 406
Score = 46.4 bits (105), Expect = 1e-04
Identities = 30/94 (31%), Positives = 47/94 (50%), Gaps = 2/94 (2%)
Frame = +3
Query: 159 VFVLDGGFSTQLTCHAGHTADGDPLWSARFLKTHPQDVINTHLDFLRAGSDIIETNTYQA 338
+ + DGGF L G+ G W+ HP+ V H +FLRAGS++++T T+ A
Sbjct: 22 IVIGDGGFVFALE-KRGYVKAGP--WTPEAAVEHPEAVRQLHREFLRAGSNVMQTFTFYA 78
Query: 339 SVDGFVKHLNLTVEE--SYELIKSAVEFARTARD 434
S D N +E+ E+ ++A + AR D
Sbjct: 79 SEDKLENRGNYVLEKISGQEVNEAACDIARQVAD 112
>BC012616-1|AAH12616.1| 406|Homo sapiens betaine-homocysteine
methyltransferase protein.
Length = 406
Score = 46.4 bits (105), Expect = 1e-04
Identities = 30/94 (31%), Positives = 47/94 (50%), Gaps = 2/94 (2%)
Frame = +3
Query: 159 VFVLDGGFSTQLTCHAGHTADGDPLWSARFLKTHPQDVINTHLDFLRAGSDIIETNTYQA 338
+ + DGGF L G+ G W+ HP+ V H +FLRAGS++++T T+ A
Sbjct: 22 IVIGDGGFVFALE-KRGYVKAGP--WTPEAAVEHPEAVRQLHREFLRAGSNVMQTFTFYA 78
Query: 339 SVDGFVKHLNLTVEE--SYELIKSAVEFARTARD 434
S D N +E+ E+ ++A + AR D
Sbjct: 79 SEDKLENRGNYVLEKISGQEVNEAACDIARQVAD 112
>AF118378-1|AAD22043.1| 406|Homo sapiens betaine-homocysteine
methyltransferase protein.
Length = 406
Score = 46.4 bits (105), Expect = 1e-04
Identities = 30/94 (31%), Positives = 47/94 (50%), Gaps = 2/94 (2%)
Frame = +3
Query: 159 VFVLDGGFSTQLTCHAGHTADGDPLWSARFLKTHPQDVINTHLDFLRAGSDIIETNTYQA 338
+ + DGGF L G+ G W+ HP+ V H +FLRAGS++++T T+ A
Sbjct: 22 IVIGDGGFVFALE-KRGYVKAGP--WTPEAAVEHPEAVRQLHREFLRAGSNVMQTFTFYA 78
Query: 339 SVDGFVKHLNLTVEE--SYELIKSAVEFARTARD 434
S D N +E+ E+ ++A + AR D
Sbjct: 79 SEDKLENRGNYVLEKISGQEVNEAACDIARQVAD 112
>BC020665-1|AAH20665.1| 363|Homo sapiens betaine-homocysteine
methyltransferase 2 protein.
Length = 363
Score = 44.0 bits (99), Expect = 6e-04
Identities = 25/68 (36%), Positives = 37/68 (54%)
Frame = +3
Query: 144 VSSKTVFVLDGGFSTQLTCHAGHTADGDPLWSARFLKTHPQDVINTHLDFLRAGSDIIET 323
+ S V + DG F L G+ G LW+ + HP V H++FLRAGS++++T
Sbjct: 17 LESGEVVIGDGSFLITLE-KRGYVKAG--LWTPEAVIEHPDAVRQLHMEFLRAGSNVMQT 73
Query: 324 NTYQASVD 347
T+ AS D
Sbjct: 74 FTFSASED 81
>AF257473-1|AAG41356.1| 363|Homo sapiens betaine-homocysteine
methyltransferase 2 protein.
Length = 363
Score = 44.0 bits (99), Expect = 6e-04
Identities = 25/68 (36%), Positives = 37/68 (54%)
Frame = +3
Query: 144 VSSKTVFVLDGGFSTQLTCHAGHTADGDPLWSARFLKTHPQDVINTHLDFLRAGSDIIET 323
+ S V + DG F L G+ G LW+ + HP V H++FLRAGS++++T
Sbjct: 17 LESGEVVIGDGSFLITLE-KRGYVKAG--LWTPEAVIEHPDAVRQLHMEFLRAGSNVMQT 73
Query: 324 NTYQASVD 347
T+ AS D
Sbjct: 74 FTFSASED 81
>AF061324-1|AAC16058.1| 1549|Homo sapiens sulfonylurea receptor 2B
protein.
Length = 1549
Score = 31.9 bits (69), Expect = 2.5
Identities = 16/43 (37%), Positives = 21/43 (48%)
Frame = +3
Query: 96 LRTINLFFYEIMSNFEVSSKTVFVLDGGFSTQLTCHAGHTADG 224
L + + FY I F V+SK + LD L CH TA+G
Sbjct: 1139 LLPLGVAFYFIQKYFRVASKDLQELDDSTQLPLLCHFSETAEG 1181
>AF061323-1|AAC16057.1| 1549|Homo sapiens sulfonylurea receptor 2A
protein.
Length = 1549
Score = 31.9 bits (69), Expect = 2.5
Identities = 16/43 (37%), Positives = 21/43 (48%)
Frame = +3
Query: 96 LRTINLFFYEIMSNFEVSSKTVFVLDGGFSTQLTCHAGHTADG 224
L + + FY I F V+SK + LD L CH TA+G
Sbjct: 1139 LLPLGVAFYFIQKYFRVASKDLQELDDSTQLPLLCHFSETAEG 1181
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 102,293,833
Number of Sequences: 237096
Number of extensions: 2207924
Number of successful extensions: 7890
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 7719
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7877
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8735159784
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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