Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= bmnc22m06
(671 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X02160-1|CAA26096.1| 1370|Homo sapiens protein ( Human mRNA for ... 120 6e-27
M32972-1|AAA59452.1| 1382|Homo sapiens insulin receptor protein. 120 6e-27
M10051-1|AAA59174.1| 1382|Homo sapiens INSR protein. 120 6e-27
BC117172-1|AAI17173.1| 1370|Homo sapiens insulin receptor protein. 120 6e-27
BC047591-1|AAH47591.1| 743|Homo sapiens INSR protein protein. 118 2e-26
AL158169-3|CAH70009.1| 1297|Homo sapiens insulin receptor-relate... 116 6e-26
J05046-1|AAC31759.1| 1268|Homo sapiens insulin receptor-related ... 112 1e-24
X04434-1|CAA28030.1| 1367|Homo sapiens IGF-I receptor protein. 106 6e-23
BC113612-1|AAI13613.1| 1367|Homo sapiens insulin-like growth fac... 106 6e-23
BC113610-1|AAI13611.1| 1367|Homo sapiens insulin-like growth fac... 106 6e-23
AY332722-1|AAP81165.1| 1367|Homo sapiens insulin-like growth fac... 106 6e-23
EF207604-1|ABP68900.1| 179|Homo sapiens insulin receptor protein. 105 1e-22
DQ333196-1|ABC46553.1| 179|Homo sapiens insulin receptor protein. 105 1e-22
EF207606-1|ABP68902.1| 167|Homo sapiens insulin receptor protein. 95 3e-19
EF207605-1|ABP68901.1| 167|Homo sapiens insulin receptor protein. 95 3e-19
X03363-1|CAA27060.1| 1255|Homo sapiens protein ( Human c-erb-B-2... 45 2e-04
M16792-1|AAA58637.1| 191|Homo sapiens HER-2/neu protein. 45 2e-04
M11730-1|AAA75493.1| 1255|Homo sapiens protein ( Human tyrosine ... 45 2e-04
AY208911-1|AAO18082.1| 1255|Homo sapiens v-erb-b2 erythroblastic... 45 2e-04
AF177761-1|AAD56009.2| 419|Homo sapiens herstatin protein. 45 2e-04
S61953-1|AAB26935.1| 183|Homo sapiens receptor tyrosine kinase ... 43 9e-04
M34309-1|AAA35979.1| 1342|Homo sapiens protein ( Human epidermal... 43 9e-04
M29366-1|AAA35790.1| 1342|Homo sapiens protein ( Human epidermal... 43 9e-04
BT007226-1|AAP35890.1| 331|Homo sapiens v-erb-b2 erythroblastic... 43 9e-04
BC082992-1|AAH82992.1| 1342|Homo sapiens v-erb-b2 erythroblastic... 43 9e-04
BC002706-1|AAH02706.1| 331|Homo sapiens ERBB3 protein protein. 43 9e-04
L07868-1|AAB59446.1| 1308|Homo sapiens receptor tyrosine kinase ... 41 0.004
BC112199-1|AAI12200.1| 1308|Homo sapiens v-erb-a erythroblastic ... 41 0.004
AC093823-1|AAY14899.1| 62|Homo sapiens unknown protein. 33 0.70
AL009182-2|CAI22773.1| 639|Homo sapiens chromosome 1 open readi... 31 3.8
AF503509-1|AAQ07593.1| 639|Homo sapiens C1orf32 putative protei... 31 3.8
D88667-1|BAA13673.1| 423|Homo sapiens cerebroside sulfotransfer... 31 5.0
CR456350-1|CAG30236.1| 423|Homo sapiens Em:AC005006.2 protein. 31 5.0
BC019077-1|AAH19077.1| 423|Homo sapiens galactose-3-O-sulfotran... 31 5.0
BC014649-1|AAH14649.1| 423|Homo sapiens GAL3ST1 protein protein. 31 5.0
AB029901-1|BAA89503.1| 423|Homo sapiens cerebroside sulfotransf... 31 5.0
AK096721-1|BAC04850.1| 180|Homo sapiens protein ( Homo sapiens ... 30 8.7
>X02160-1|CAA26096.1| 1370|Homo sapiens protein ( Human mRNA for
insulin receptor precursor. ).
Length = 1370
Score = 120 bits (288), Expect = 6e-27
Identities = 62/129 (48%), Positives = 85/129 (65%), Gaps = 2/129 (1%)
Frame = +1
Query: 289 AVACALLIACARTYAGT--EVVPARGVCPSMDLRNNPDQIRRLEGCRVIEGQLSIVLMER 462
A A LL+A A G + P VCP MD+RNN ++ LE C VIEG L I+LM +
Sbjct: 9 AAAAPLLVAVAALLLGAAGHLYPGE-VCPGMDIRNNLTRLHELENCSVIEGHLQILLMFK 67
Query: 463 ATNKIFDNMSFPQLREVTGYILIYRTKGLRNLGDLFPNLTVVRGMQLFKDFALVIFDNEH 642
+ F ++SFP+L +T Y+L++R GL +L DLFPNLTV+RG +LF ++ALVIF+ H
Sbjct: 68 TRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYALVIFEMVH 127
Query: 643 LEALGLNSL 669
L+ LGL +L
Sbjct: 128 LKELGLYNL 136
>M32972-1|AAA59452.1| 1382|Homo sapiens insulin receptor protein.
Length = 1382
Score = 120 bits (288), Expect = 6e-27
Identities = 62/129 (48%), Positives = 85/129 (65%), Gaps = 2/129 (1%)
Frame = +1
Query: 289 AVACALLIACARTYAGT--EVVPARGVCPSMDLRNNPDQIRRLEGCRVIEGQLSIVLMER 462
A A LL+A A G + P VCP MD+RNN ++ LE C VIEG L I+LM +
Sbjct: 9 AAAAPLLVAVAALLLGAAGHLYPGE-VCPGMDIRNNLTRLHELENCSVIEGHLQILLMFK 67
Query: 463 ATNKIFDNMSFPQLREVTGYILIYRTKGLRNLGDLFPNLTVVRGMQLFKDFALVIFDNEH 642
+ F ++SFP+L +T Y+L++R GL +L DLFPNLTV+RG +LF ++ALVIF+ H
Sbjct: 68 TRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYALVIFEMVH 127
Query: 643 LEALGLNSL 669
L+ LGL +L
Sbjct: 128 LKELGLYNL 136
>M10051-1|AAA59174.1| 1382|Homo sapiens INSR protein.
Length = 1382
Score = 120 bits (288), Expect = 6e-27
Identities = 62/129 (48%), Positives = 85/129 (65%), Gaps = 2/129 (1%)
Frame = +1
Query: 289 AVACALLIACARTYAGT--EVVPARGVCPSMDLRNNPDQIRRLEGCRVIEGQLSIVLMER 462
A A LL+A A G + P VCP MD+RNN ++ LE C VIEG L I+LM +
Sbjct: 9 AAAAPLLVAVAALLLGAAGHLYPGE-VCPGMDIRNNLTRLHELENCSVIEGHLQILLMFK 67
Query: 463 ATNKIFDNMSFPQLREVTGYILIYRTKGLRNLGDLFPNLTVVRGMQLFKDFALVIFDNEH 642
+ F ++SFP+L +T Y+L++R GL +L DLFPNLTV+RG +LF ++ALVIF+ H
Sbjct: 68 TRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYALVIFEMVH 127
Query: 643 LEALGLNSL 669
L+ LGL +L
Sbjct: 128 LKELGLYNL 136
>BC117172-1|AAI17173.1| 1370|Homo sapiens insulin receptor protein.
Length = 1370
Score = 120 bits (288), Expect = 6e-27
Identities = 62/129 (48%), Positives = 85/129 (65%), Gaps = 2/129 (1%)
Frame = +1
Query: 289 AVACALLIACARTYAGT--EVVPARGVCPSMDLRNNPDQIRRLEGCRVIEGQLSIVLMER 462
A A LL+A A G + P VCP MD+RNN ++ LE C VIEG L I+LM +
Sbjct: 9 AAAAPLLVAVAALLLGAAGHLYPGE-VCPGMDIRNNLTRLHELENCSVIEGHLQILLMFK 67
Query: 463 ATNKIFDNMSFPQLREVTGYILIYRTKGLRNLGDLFPNLTVVRGMQLFKDFALVIFDNEH 642
+ F ++SFP+L +T Y+L++R GL +L DLFPNLTV+RG +LF ++ALVIF+ H
Sbjct: 68 TRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYALVIFEMVH 127
Query: 643 LEALGLNSL 669
L+ LGL +L
Sbjct: 128 LKELGLYNL 136
>BC047591-1|AAH47591.1| 743|Homo sapiens INSR protein protein.
Length = 743
Score = 118 bits (284), Expect = 2e-26
Identities = 62/127 (48%), Positives = 83/127 (65%)
Frame = +1
Query: 289 AVACALLIACARTYAGTEVVPARGVCPSMDLRNNPDQIRRLEGCRVIEGQLSIVLMERAT 468
AVA LL A Y G VCP MD+RNN ++ LE C VIEG L I+LM +
Sbjct: 8 AVAALLLGAAGHLYPGE-------VCPGMDIRNNLTRLHELENCSVIEGHLQILLMFKTR 60
Query: 469 NKIFDNMSFPQLREVTGYILIYRTKGLRNLGDLFPNLTVVRGMQLFKDFALVIFDNEHLE 648
+ F ++SFP+L +T Y+L++R GL +L DLFPNLTV+RG +LF ++ALVIF+ HL+
Sbjct: 61 PEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYALVIFEMVHLK 120
Query: 649 ALGLNSL 669
LGL +L
Sbjct: 121 ELGLYNL 127
>AL158169-3|CAH70009.1| 1297|Homo sapiens insulin receptor-related
receptor protein.
Length = 1297
Score = 116 bits (280), Expect = 6e-26
Identities = 59/129 (45%), Positives = 85/129 (65%)
Frame = +1
Query: 283 WPAVACALLIACARTYAGTEVVPARGVCPSMDLRNNPDQIRRLEGCRVIEGQLSIVLMER 462
WP AC +I + + G + V VCPS+D+R+ ++R+LE C V+EG L I+LM
Sbjct: 7 WPWGACLPVIFLSLGF-GLDTVE---VCPSLDIRSEVAELRQLENCSVVEGHLQILLMFT 62
Query: 463 ATNKIFDNMSFPQLREVTGYILIYRTKGLRNLGDLFPNLTVVRGMQLFKDFALVIFDNEH 642
AT + F +SFP+L +VT Y+L++R GL +L DLFPNL V+RG +LF +ALVIF+ H
Sbjct: 63 ATGEDFRGLSFPRLTQVTDYLLLFRVYGLESLRDLFPNLAVIRGTRLFLGYALVIFEMPH 122
Query: 643 LEALGLNSL 669
L + L +L
Sbjct: 123 LRDVALPAL 131
>J05046-1|AAC31759.1| 1268|Homo sapiens insulin receptor-related
receptor protein.
Length = 1268
Score = 112 bits (269), Expect = 1e-24
Identities = 51/102 (50%), Positives = 73/102 (71%)
Frame = +1
Query: 364 CPSMDLRNNPDQIRRLEGCRVIEGQLSIVLMERATNKIFDNMSFPQLREVTGYILIYRTK 543
CPS+D+R+ ++R+LE C V+EG L I+LM AT + F +SFP+L +VT Y+L++R
Sbjct: 1 CPSLDIRSEVAELRQLENCSVVEGHLQILLMFTATGEDFRGLSFPRLTQVTDYLLLFRVY 60
Query: 544 GLRNLGDLFPNLTVVRGMQLFKDFALVIFDNEHLEALGLNSL 669
GL +L DLFPNL V+RG +LF +ALVIF+ HL + L +L
Sbjct: 61 GLESLRDLFPNLAVIRGTRLFLGYALVIFEMPHLRDVALPAL 102
>X04434-1|CAA28030.1| 1367|Homo sapiens IGF-I receptor protein.
Length = 1367
Score = 106 bits (255), Expect = 6e-23
Identities = 53/115 (46%), Positives = 81/115 (70%), Gaps = 2/115 (1%)
Frame = +1
Query: 331 AGTEVVPARG-VC-PSMDLRNNPDQIRRLEGCRVIEGQLSIVLMERATNKIFDNMSFPQL 504
A + P G +C P +D+RN+ Q++RLE C VIEG L I+L+ +A + + + FP+L
Sbjct: 21 AALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGYLHILLISKAED--YRSYRFPKL 78
Query: 505 REVTGYILIYRTKGLRNLGDLFPNLTVVRGMQLFKDFALVIFDNEHLEALGLNSL 669
+T Y+L++R GL +LGDLFPNLTV+RG +LF ++ALVIF+ +L+ +GL +L
Sbjct: 79 TVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIFEMTNLKDIGLYNL 133
Score = 38.7 bits (86), Expect = 0.019
Identities = 32/112 (28%), Positives = 56/112 (50%), Gaps = 9/112 (8%)
Frame = +1
Query: 346 VPARGVCPSMDLRNNP----DQI---RRLEGCRVIEGQLSIVLMERATNKIFDNMSFPQL 504
+P G CP + D + + L+GC + +G L ++ + R N + +F L
Sbjct: 322 IPCEGPCPKVCEEEKKTKTIDSVTSAQMLQGCTIFKGNL-LINIRRGNNIASELENFMGL 380
Query: 505 REV-TGYILIYRTKGLRNLGDLFPNLTVVRGM-QLFKDFALVIFDNEHLEAL 654
EV TGY+ I + L +L L NL ++ G QL +++ + DN++L+ L
Sbjct: 381 IEVVTGYVKIRHSHALVSLSFL-KNLRLILGEEQLEGNYSFYVLDNQNLQQL 431
>BC113612-1|AAI13613.1| 1367|Homo sapiens insulin-like growth factor
1 receptor protein.
Length = 1367
Score = 106 bits (255), Expect = 6e-23
Identities = 53/115 (46%), Positives = 81/115 (70%), Gaps = 2/115 (1%)
Frame = +1
Query: 331 AGTEVVPARG-VC-PSMDLRNNPDQIRRLEGCRVIEGQLSIVLMERATNKIFDNMSFPQL 504
A + P G +C P +D+RN+ Q++RLE C VIEG L I+L+ +A + + + FP+L
Sbjct: 21 AALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGYLHILLISKAED--YRSYRFPKL 78
Query: 505 REVTGYILIYRTKGLRNLGDLFPNLTVVRGMQLFKDFALVIFDNEHLEALGLNSL 669
+T Y+L++R GL +LGDLFPNLTV+RG +LF ++ALVIF+ +L+ +GL +L
Sbjct: 79 TVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIFEMTNLKDIGLYNL 133
Score = 38.7 bits (86), Expect = 0.019
Identities = 32/112 (28%), Positives = 56/112 (50%), Gaps = 9/112 (8%)
Frame = +1
Query: 346 VPARGVCPSMDLRNNP----DQI---RRLEGCRVIEGQLSIVLMERATNKIFDNMSFPQL 504
+P G CP + D + + L+GC + +G L ++ + R N + +F L
Sbjct: 322 IPCEGPCPKVCEEEKKTKTIDSVTSAQMLQGCTIFKGNL-LINIRRGNNIASELENFMGL 380
Query: 505 REV-TGYILIYRTKGLRNLGDLFPNLTVVRGM-QLFKDFALVIFDNEHLEAL 654
EV TGY+ I + L +L L NL ++ G QL +++ + DN++L+ L
Sbjct: 381 IEVVTGYVKIRHSHALVSLSFL-KNLRLILGEEQLEGNYSFYVLDNQNLQQL 431
>BC113610-1|AAI13611.1| 1367|Homo sapiens insulin-like growth factor
1 receptor protein.
Length = 1367
Score = 106 bits (255), Expect = 6e-23
Identities = 53/115 (46%), Positives = 81/115 (70%), Gaps = 2/115 (1%)
Frame = +1
Query: 331 AGTEVVPARG-VC-PSMDLRNNPDQIRRLEGCRVIEGQLSIVLMERATNKIFDNMSFPQL 504
A + P G +C P +D+RN+ Q++RLE C VIEG L I+L+ +A + + + FP+L
Sbjct: 21 AALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGYLHILLISKAED--YRSYRFPKL 78
Query: 505 REVTGYILIYRTKGLRNLGDLFPNLTVVRGMQLFKDFALVIFDNEHLEALGLNSL 669
+T Y+L++R GL +LGDLFPNLTV+RG +LF ++ALVIF+ +L+ +GL +L
Sbjct: 79 TVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIFEMTNLKDIGLYNL 133
Score = 38.7 bits (86), Expect = 0.019
Identities = 32/112 (28%), Positives = 56/112 (50%), Gaps = 9/112 (8%)
Frame = +1
Query: 346 VPARGVCPSMDLRNNP----DQI---RRLEGCRVIEGQLSIVLMERATNKIFDNMSFPQL 504
+P G CP + D + + L+GC + +G L ++ + R N + +F L
Sbjct: 322 IPCEGPCPKVCEEEKKTKTIDSVTSAQMLQGCTIFKGNL-LINIRRGNNIASELENFMGL 380
Query: 505 REV-TGYILIYRTKGLRNLGDLFPNLTVVRGM-QLFKDFALVIFDNEHLEAL 654
EV TGY+ I + L +L L NL ++ G QL +++ + DN++L+ L
Sbjct: 381 IEVVTGYVKIRHSHALVSLSFL-KNLRLILGEEQLEGNYSFYVLDNQNLQQL 431
>AY332722-1|AAP81165.1| 1367|Homo sapiens insulin-like growth factor
1 receptor protein.
Length = 1367
Score = 106 bits (255), Expect = 6e-23
Identities = 53/115 (46%), Positives = 81/115 (70%), Gaps = 2/115 (1%)
Frame = +1
Query: 331 AGTEVVPARG-VC-PSMDLRNNPDQIRRLEGCRVIEGQLSIVLMERATNKIFDNMSFPQL 504
A + P G +C P +D+RN+ Q++RLE C VIEG L I+L+ +A + + + FP+L
Sbjct: 21 AALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGYLHILLISKAED--YRSYRFPKL 78
Query: 505 REVTGYILIYRTKGLRNLGDLFPNLTVVRGMQLFKDFALVIFDNEHLEALGLNSL 669
+T Y+L++R GL +LGDLFPNLTV+RG +LF ++ALVIF+ +L+ +GL +L
Sbjct: 79 TVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIFEMTNLKDIGLYNL 133
Score = 38.7 bits (86), Expect = 0.019
Identities = 32/112 (28%), Positives = 56/112 (50%), Gaps = 9/112 (8%)
Frame = +1
Query: 346 VPARGVCPSMDLRNNP----DQI---RRLEGCRVIEGQLSIVLMERATNKIFDNMSFPQL 504
+P G CP + D + + L+GC + +G L ++ + R N + +F L
Sbjct: 322 IPCEGPCPKVCEEEKKTKTIDSVTSAQMLQGCTIFKGNL-LINIRRGNNIASELENFMGL 380
Query: 505 REV-TGYILIYRTKGLRNLGDLFPNLTVVRGM-QLFKDFALVIFDNEHLEAL 654
EV TGY+ I + L +L L NL ++ G QL +++ + DN++L+ L
Sbjct: 381 IEVVTGYVKIRHSHALVSLSFL-KNLRLILGEEQLEGNYSFYVLDNQNLQQL 431
>EF207604-1|ABP68900.1| 179|Homo sapiens insulin receptor protein.
Length = 179
Score = 105 bits (253), Expect = 1e-22
Identities = 50/98 (51%), Positives = 71/98 (72%)
Frame = +1
Query: 376 DLRNNPDQIRRLEGCRVIEGQLSIVLMERATNKIFDNMSFPQLREVTGYILIYRTKGLRN 555
D+RNN ++ LE C VIEG L I+LM + + F ++SFP+L +T Y+L++R GL +
Sbjct: 1 DIRNNLTRLHELENCSVIEGHLQILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLES 60
Query: 556 LGDLFPNLTVVRGMQLFKDFALVIFDNEHLEALGLNSL 669
L DLFPNLTV+RG +LF ++ALVIF+ HL+ LGL +L
Sbjct: 61 LKDLFPNLTVIRGSRLFFNYALVIFEMVHLKELGLYNL 98
>DQ333196-1|ABC46553.1| 179|Homo sapiens insulin receptor protein.
Length = 179
Score = 105 bits (253), Expect = 1e-22
Identities = 50/98 (51%), Positives = 71/98 (72%)
Frame = +1
Query: 376 DLRNNPDQIRRLEGCRVIEGQLSIVLMERATNKIFDNMSFPQLREVTGYILIYRTKGLRN 555
D+RNN ++ LE C VIEG L I+LM + + F ++SFP+L +T Y+L++R GL +
Sbjct: 1 DIRNNLTRLHELENCSVIEGHLQILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLES 60
Query: 556 LGDLFPNLTVVRGMQLFKDFALVIFDNEHLEALGLNSL 669
L DLFPNLTV+RG +LF ++ALVIF+ HL+ LGL +L
Sbjct: 61 LKDLFPNLTVIRGSRLFFNYALVIFEMVHLKELGLYNL 98
>EF207606-1|ABP68902.1| 167|Homo sapiens insulin receptor protein.
Length = 167
Score = 94.7 bits (225), Expect = 3e-19
Identities = 45/86 (52%), Positives = 63/86 (73%)
Frame = +1
Query: 412 EGCRVIEGQLSIVLMERATNKIFDNMSFPQLREVTGYILIYRTKGLRNLGDLFPNLTVVR 591
E C VIEG L I+LM + + F ++SFP+L +T Y+L++R GL +L DLFPNLTV+R
Sbjct: 1 ENCSVIEGHLQILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIR 60
Query: 592 GMQLFKDFALVIFDNEHLEALGLNSL 669
G +LF ++ALVIF+ HL+ LGL +L
Sbjct: 61 GSRLFFNYALVIFEMVHLKELGLYNL 86
>EF207605-1|ABP68901.1| 167|Homo sapiens insulin receptor protein.
Length = 167
Score = 94.7 bits (225), Expect = 3e-19
Identities = 45/86 (52%), Positives = 63/86 (73%)
Frame = +1
Query: 412 EGCRVIEGQLSIVLMERATNKIFDNMSFPQLREVTGYILIYRTKGLRNLGDLFPNLTVVR 591
E C VIEG L I+LM + + F ++SFP+L +T Y+L++R GL +L DLFPNLTV+R
Sbjct: 1 ENCSVIEGHLQILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIR 60
Query: 592 GMQLFKDFALVIFDNEHLEALGLNSL 669
G +LF ++ALVIF+ HL+ LGL +L
Sbjct: 61 GSRLFFNYALVIFEMVHLKELGLYNL 86
>X03363-1|CAA27060.1| 1255|Homo sapiens protein ( Human c-erb-B-2
mRNA. ).
Length = 1255
Score = 45.2 bits (102), Expect = 2e-04
Identities = 32/84 (38%), Positives = 51/84 (60%), Gaps = 3/84 (3%)
Frame = +1
Query: 394 DQIRRL-EGCRVIEGQLSIVLMERATNKIFDNMSFPQ-LREVTGYILIYRTKGLRNLGDL 567
D +R L +GC+V++G L + + TN ++SF Q ++EV GY+LI + +R +
Sbjct: 44 DMLRHLYQGCQVVQGNLELTYLP--TNA---SLSFLQDIQEVQGYVLIAHNQ-VRQVP-- 95
Query: 568 FPNLTVVRGMQLFKD-FALVIFDN 636
L +VRG QLF+D +AL + DN
Sbjct: 96 LQRLRIVRGTQLFEDNYALAVLDN 119
>M16792-1|AAA58637.1| 191|Homo sapiens HER-2/neu protein.
Length = 191
Score = 45.2 bits (102), Expect = 2e-04
Identities = 32/84 (38%), Positives = 51/84 (60%), Gaps = 3/84 (3%)
Frame = +1
Query: 394 DQIRRL-EGCRVIEGQLSIVLMERATNKIFDNMSFPQ-LREVTGYILIYRTKGLRNLGDL 567
D +R L +GC+V++G L + + TN ++SF Q ++EV GY+LI + +R +
Sbjct: 44 DMLRHLYQGCQVVQGNLELTYLP--TNA---SLSFLQDIQEVQGYVLIAHNQ-VRQVP-- 95
Query: 568 FPNLTVVRGMQLFKD-FALVIFDN 636
L +VRG QLF+D +AL + DN
Sbjct: 96 LQRLRIVRGTQLFEDNYALAVLDN 119
>M11730-1|AAA75493.1| 1255|Homo sapiens protein ( Human tyrosine
kinase-type receptor (HER2) mRNA, complete cds. ).
Length = 1255
Score = 45.2 bits (102), Expect = 2e-04
Identities = 32/84 (38%), Positives = 51/84 (60%), Gaps = 3/84 (3%)
Frame = +1
Query: 394 DQIRRL-EGCRVIEGQLSIVLMERATNKIFDNMSFPQ-LREVTGYILIYRTKGLRNLGDL 567
D +R L +GC+V++G L + + TN ++SF Q ++EV GY+LI + +R +
Sbjct: 44 DMLRHLYQGCQVVQGNLELTYLP--TNA---SLSFLQDIQEVQGYVLIAHNQ-VRQVP-- 95
Query: 568 FPNLTVVRGMQLFKD-FALVIFDN 636
L +VRG QLF+D +AL + DN
Sbjct: 96 LQRLRIVRGTQLFEDNYALAVLDN 119
>AY208911-1|AAO18082.1| 1255|Homo sapiens v-erb-b2 erythroblastic
leukemia viral oncogene homolog 2, neuro/glioblastoma d
protein.
Length = 1255
Score = 45.2 bits (102), Expect = 2e-04
Identities = 32/84 (38%), Positives = 51/84 (60%), Gaps = 3/84 (3%)
Frame = +1
Query: 394 DQIRRL-EGCRVIEGQLSIVLMERATNKIFDNMSFPQ-LREVTGYILIYRTKGLRNLGDL 567
D +R L +GC+V++G L + + TN ++SF Q ++EV GY+LI + +R +
Sbjct: 44 DMLRHLYQGCQVVQGNLELTYLP--TNA---SLSFLQDIQEVQGYVLIAHNQ-VRQVP-- 95
Query: 568 FPNLTVVRGMQLFKD-FALVIFDN 636
L +VRG QLF+D +AL + DN
Sbjct: 96 LQRLRIVRGTQLFEDNYALAVLDN 119
>AF177761-1|AAD56009.2| 419|Homo sapiens herstatin protein.
Length = 419
Score = 45.2 bits (102), Expect = 2e-04
Identities = 32/84 (38%), Positives = 51/84 (60%), Gaps = 3/84 (3%)
Frame = +1
Query: 394 DQIRRL-EGCRVIEGQLSIVLMERATNKIFDNMSFPQ-LREVTGYILIYRTKGLRNLGDL 567
D +R L +GC+V++G L + + TN ++SF Q ++EV GY+LI + +R +
Sbjct: 44 DMLRHLYQGCQVVQGNLELTYLP--TNA---SLSFLQDIQEVQGYVLIAHNQ-VRQVP-- 95
Query: 568 FPNLTVVRGMQLFKD-FALVIFDN 636
L +VRG QLF+D +AL + DN
Sbjct: 96 LQRLRIVRGTQLFEDNYALAVLDN 119
>S61953-1|AAB26935.1| 183|Homo sapiens receptor tyrosine kinase
protein.
Length = 183
Score = 43.2 bits (97), Expect = 9e-04
Identities = 43/123 (34%), Positives = 60/123 (48%), Gaps = 12/123 (9%)
Frame = +1
Query: 304 LLIACARTYAGTEVVPARGVCPSM--------DLRNNPDQIRRL-EGCRVIEGQLSIVLM 456
LL + AR G+EV ++ VCP D N + +L E C V+ G L IVL
Sbjct: 12 LLFSLAR---GSEVGNSQAVCPGTLNGLSVTGDAENQYQTLYKLYERCEVVMGNLEIVLT 68
Query: 457 ERATNKIFDNMSFPQ-LREVTGYILIYRTKGLRNLGDL-FPNLTVVRGMQLFK-DFALVI 627
+ +SF Q +REVTGY+L+ + L PNL VVRG Q++ FA+ +
Sbjct: 69 GHNAD-----LSFLQWIREVTGYVLV----AMNEFSTLPLPNLRVVRGTQVYDGKFAIFV 119
Query: 628 FDN 636
N
Sbjct: 120 MLN 122
>M34309-1|AAA35979.1| 1342|Homo sapiens protein ( Human epidermal
growth factor receptor (HER3) mRNA, complete cds. ).
Length = 1342
Score = 43.2 bits (97), Expect = 9e-04
Identities = 43/123 (34%), Positives = 60/123 (48%), Gaps = 12/123 (9%)
Frame = +1
Query: 304 LLIACARTYAGTEVVPARGVCPSM--------DLRNNPDQIRRL-EGCRVIEGQLSIVLM 456
LL + AR G+EV ++ VCP D N + +L E C V+ G L IVL
Sbjct: 12 LLFSLAR---GSEVGNSQAVCPGTLNGLSVTGDAENQYQTLYKLYERCEVVMGNLEIVLT 68
Query: 457 ERATNKIFDNMSFPQ-LREVTGYILIYRTKGLRNLGDL-FPNLTVVRGMQLFK-DFALVI 627
+ +SF Q +REVTGY+L+ + L PNL VVRG Q++ FA+ +
Sbjct: 69 GHNAD-----LSFLQWIREVTGYVLV----AMNEFSTLPLPNLRVVRGTQVYDGKFAIFV 119
Query: 628 FDN 636
N
Sbjct: 120 MLN 122
>M29366-1|AAA35790.1| 1342|Homo sapiens protein ( Human epidermal
growth factor receptor (ERBB3) mRNA, complete cds. ).
Length = 1342
Score = 43.2 bits (97), Expect = 9e-04
Identities = 43/123 (34%), Positives = 60/123 (48%), Gaps = 12/123 (9%)
Frame = +1
Query: 304 LLIACARTYAGTEVVPARGVCPSM--------DLRNNPDQIRRL-EGCRVIEGQLSIVLM 456
LL + AR G+EV ++ VCP D N + +L E C V+ G L IVL
Sbjct: 12 LLFSLAR---GSEVGNSQAVCPGTLNGLSVTGDAENQYQTLYKLYERCEVVMGNLEIVLT 68
Query: 457 ERATNKIFDNMSFPQ-LREVTGYILIYRTKGLRNLGDL-FPNLTVVRGMQLFK-DFALVI 627
+ +SF Q +REVTGY+L+ + L PNL VVRG Q++ FA+ +
Sbjct: 69 GHNAD-----LSFLQWIREVTGYVLV----AMNEFSTLPLPNLRVVRGTQVYDGKFAIFV 119
Query: 628 FDN 636
N
Sbjct: 120 MLN 122
>BT007226-1|AAP35890.1| 331|Homo sapiens v-erb-b2 erythroblastic
leukemia viral oncogene homolog 3 (avian) protein.
Length = 331
Score = 43.2 bits (97), Expect = 9e-04
Identities = 43/123 (34%), Positives = 60/123 (48%), Gaps = 12/123 (9%)
Frame = +1
Query: 304 LLIACARTYAGTEVVPARGVCPSM--------DLRNNPDQIRRL-EGCRVIEGQLSIVLM 456
LL + AR G+EV ++ VCP D N + +L E C V+ G L IVL
Sbjct: 12 LLFSLAR---GSEVGNSQAVCPGTLNGLSVTGDAENQYQTLYKLYERCEVVMGNLEIVLT 68
Query: 457 ERATNKIFDNMSFPQ-LREVTGYILIYRTKGLRNLGDL-FPNLTVVRGMQLFK-DFALVI 627
+ +SF Q +REVTGY+L+ + L PNL VVRG Q++ FA+ +
Sbjct: 69 GHNAD-----LSFLQWIREVTGYVLV----AMNEFSTLPLPNLRVVRGTQVYDGKFAIFV 119
Query: 628 FDN 636
N
Sbjct: 120 MLN 122
>BC082992-1|AAH82992.1| 1342|Homo sapiens v-erb-b2 erythroblastic
leukemia viral oncogene homolog 3 (avian) protein.
Length = 1342
Score = 43.2 bits (97), Expect = 9e-04
Identities = 43/123 (34%), Positives = 60/123 (48%), Gaps = 12/123 (9%)
Frame = +1
Query: 304 LLIACARTYAGTEVVPARGVCPSM--------DLRNNPDQIRRL-EGCRVIEGQLSIVLM 456
LL + AR G+EV ++ VCP D N + +L E C V+ G L IVL
Sbjct: 12 LLFSLAR---GSEVGNSQAVCPGTLNGLSVTGDAENQYQTLYKLYERCEVVMGNLEIVLT 68
Query: 457 ERATNKIFDNMSFPQ-LREVTGYILIYRTKGLRNLGDL-FPNLTVVRGMQLFK-DFALVI 627
+ +SF Q +REVTGY+L+ + L PNL VVRG Q++ FA+ +
Sbjct: 69 GHNAD-----LSFLQWIREVTGYVLV----AMNEFSTLPLPNLRVVRGTQVYDGKFAIFV 119
Query: 628 FDN 636
N
Sbjct: 120 MLN 122
>BC002706-1|AAH02706.1| 331|Homo sapiens ERBB3 protein protein.
Length = 331
Score = 43.2 bits (97), Expect = 9e-04
Identities = 43/123 (34%), Positives = 60/123 (48%), Gaps = 12/123 (9%)
Frame = +1
Query: 304 LLIACARTYAGTEVVPARGVCPSM--------DLRNNPDQIRRL-EGCRVIEGQLSIVLM 456
LL + AR G+EV ++ VCP D N + +L E C V+ G L IVL
Sbjct: 12 LLFSLAR---GSEVGNSQAVCPGTLNGLSVTGDAENQYQTLYKLYERCEVVMGNLEIVLT 68
Query: 457 ERATNKIFDNMSFPQ-LREVTGYILIYRTKGLRNLGDL-FPNLTVVRGMQLFK-DFALVI 627
+ +SF Q +REVTGY+L+ + L PNL VVRG Q++ FA+ +
Sbjct: 69 GHNAD-----LSFLQWIREVTGYVLV----AMNEFSTLPLPNLRVVRGTQVYDGKFAIFV 119
Query: 628 FDN 636
N
Sbjct: 120 MLN 122
>L07868-1|AAB59446.1| 1308|Homo sapiens receptor tyrosine kinase
protein.
Length = 1308
Score = 41.1 bits (92), Expect = 0.004
Identities = 34/101 (33%), Positives = 50/101 (49%), Gaps = 3/101 (2%)
Frame = +1
Query: 376 DLRNNPDQIRRL-EGCRVIEGQLSIVLMERATNKIFDNMSFPQLREVTGYILIYRTKGLR 552
DL +R+ E C V+ G L I +E + F +REVTGY+L+ + R
Sbjct: 41 DLEQQYRALRKYYENCEVVMGNLEITSIEHNRDLSF----LRSVREVTGYVLVALNQ-FR 95
Query: 553 NLGDLFPNLTVVRGMQLFKD-FALVIFDNEHLEA-LGLNSL 669
L NL ++RG +L++D +AL IF N + GL L
Sbjct: 96 YLP--LENLRIIRGTKLYEDRYALAIFLNYRKDGNFGLQEL 134
>BC112199-1|AAI12200.1| 1308|Homo sapiens v-erb-a erythroblastic
leukemia viral oncogene homolog 4 (avian) protein.
Length = 1308
Score = 41.1 bits (92), Expect = 0.004
Identities = 34/101 (33%), Positives = 50/101 (49%), Gaps = 3/101 (2%)
Frame = +1
Query: 376 DLRNNPDQIRRL-EGCRVIEGQLSIVLMERATNKIFDNMSFPQLREVTGYILIYRTKGLR 552
DL +R+ E C V+ G L I +E + F +REVTGY+L+ + R
Sbjct: 41 DLEQQYRALRKYYENCEVVMGNLEITSIEHNRDLSF----LRSVREVTGYVLVALNQ-FR 95
Query: 553 NLGDLFPNLTVVRGMQLFKD-FALVIFDNEHLEA-LGLNSL 669
L NL ++RG +L++D +AL IF N + GL L
Sbjct: 96 YLP--LENLRIIRGTKLYEDRYALAIFLNYRKDGNFGLQEL 134
>AC093823-1|AAY14899.1| 62|Homo sapiens unknown protein.
Length = 62
Score = 33.5 bits (73), Expect = 0.70
Identities = 23/58 (39%), Positives = 34/58 (58%), Gaps = 2/58 (3%)
Frame = +1
Query: 502 LREVTGYILIYRTKGLRNLGDLFPNLTVVRGMQLFKD-FALVIFDNEHLEA-LGLNSL 669
+REVTGY+L+ + R L NL ++RG +L++D +AL IF N + GL L
Sbjct: 2 VREVTGYVLVALNQ-FRYLP--LENLRIIRGTKLYEDRYALAIFLNYRKDGNFGLQEL 56
>AL009182-2|CAI22773.1| 639|Homo sapiens chromosome 1 open reading
frame 32 protein.
Length = 639
Score = 31.1 bits (67), Expect = 3.8
Identities = 11/24 (45%), Positives = 12/24 (50%)
Frame = +1
Query: 31 WFVCCPLSIACLQLCCYCFNSLCC 102
W CCP S C C C +S CC
Sbjct: 208 WCQCCPHSCCCYVRCPCCPDSCCC 231
>AF503509-1|AAQ07593.1| 639|Homo sapiens C1orf32 putative protein
protein.
Length = 639
Score = 31.1 bits (67), Expect = 3.8
Identities = 11/24 (45%), Positives = 12/24 (50%)
Frame = +1
Query: 31 WFVCCPLSIACLQLCCYCFNSLCC 102
W CCP S C C C +S CC
Sbjct: 208 WCQCCPHSCCCYVRCPCCPDSCCC 231
>D88667-1|BAA13673.1| 423|Homo sapiens cerebroside sulfotransferase
protein.
Length = 423
Score = 30.7 bits (66), Expect = 5.0
Identities = 18/47 (38%), Positives = 26/47 (55%), Gaps = 2/47 (4%)
Frame = -1
Query: 362 TPRAGTTSVPAYVRAQAISRAHATAG--QPRRSQARLITPRRTSSML 228
TP A + P + +A+ RA+ +AG QPRR+ L T + SS L
Sbjct: 45 TPEAAASCSPPALEPEAVIRANGSAGECQPRRNIVFLKTHKTASSTL 91
>CR456350-1|CAG30236.1| 423|Homo sapiens Em:AC005006.2 protein.
Length = 423
Score = 30.7 bits (66), Expect = 5.0
Identities = 18/47 (38%), Positives = 26/47 (55%), Gaps = 2/47 (4%)
Frame = -1
Query: 362 TPRAGTTSVPAYVRAQAISRAHATAG--QPRRSQARLITPRRTSSML 228
TP A + P + +A+ RA+ +AG QPRR+ L T + SS L
Sbjct: 45 TPEAAASCSPPALEPEAVIRANGSAGECQPRRNIVFLKTHKTASSTL 91
>BC019077-1|AAH19077.1| 423|Homo sapiens
galactose-3-O-sulfotransferase 1 protein.
Length = 423
Score = 30.7 bits (66), Expect = 5.0
Identities = 18/47 (38%), Positives = 26/47 (55%), Gaps = 2/47 (4%)
Frame = -1
Query: 362 TPRAGTTSVPAYVRAQAISRAHATAG--QPRRSQARLITPRRTSSML 228
TP A + P + +A+ RA+ +AG QPRR+ L T + SS L
Sbjct: 45 TPEAAASCSPPALEPEAVIRANGSAGECQPRRNIVFLKTHKTASSTL 91
>BC014649-1|AAH14649.1| 423|Homo sapiens GAL3ST1 protein protein.
Length = 423
Score = 30.7 bits (66), Expect = 5.0
Identities = 18/47 (38%), Positives = 26/47 (55%), Gaps = 2/47 (4%)
Frame = -1
Query: 362 TPRAGTTSVPAYVRAQAISRAHATAG--QPRRSQARLITPRRTSSML 228
TP A + P + +A+ RA+ +AG QPRR+ L T + SS L
Sbjct: 45 TPEAAASCSPPALEPEAVIRANGSAGECQPRRNIVFLKTHKTASSTL 91
>AB029901-1|BAA89503.1| 423|Homo sapiens cerebroside
sulfotransferase protein.
Length = 423
Score = 30.7 bits (66), Expect = 5.0
Identities = 18/47 (38%), Positives = 26/47 (55%), Gaps = 2/47 (4%)
Frame = -1
Query: 362 TPRAGTTSVPAYVRAQAISRAHATAG--QPRRSQARLITPRRTSSML 228
TP A + P + +A+ RA+ +AG QPRR+ L T + SS L
Sbjct: 45 TPEAAASCSPPALEPEAVIRANGSAGECQPRRNIVFLKTHKTASSTL 91
>AK096721-1|BAC04850.1| 180|Homo sapiens protein ( Homo sapiens
cDNA FLJ39402 fis, clone PLACE6011975. ).
Length = 180
Score = 29.9 bits (64), Expect = 8.7
Identities = 23/78 (29%), Positives = 31/78 (39%), Gaps = 4/78 (5%)
Frame = +3
Query: 219 SCGQHAGGAAWRDEARL*PSWLARGGVRSADSLR---THIRRHRSC-TCTGSMSVNGPTK 386
+CG+ AG W++ ARG R A + R R C G ++V GP +
Sbjct: 16 ACGRQAGREGWQESRSRAGCGRARGPDREAVAARGDSLGAGPGRPCPALRGRLAVYGPPR 75
Query: 387 QSGPDQTFGRMSGDRGSA 440
Q GR G G A
Sbjct: 76 AGSAAQRRGRRQGQGGGA 93
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 97,626,040
Number of Sequences: 237096
Number of extensions: 2102012
Number of successful extensions: 4998
Number of sequences better than 10.0: 37
Number of HSP's better than 10.0 without gapping: 4697
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4971
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 7647512560
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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