Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= bmnc20c05
(683 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC036451-1|AAH36451.1| 484|Homo sapiens cathepsin F protein. 142 8e-34
BC011682-1|AAH11682.1| 484|Homo sapiens cathepsin F protein. 142 8e-34
AL137742-1|CAB70900.1| 308|Homo sapiens hypothetical protein pr... 142 8e-34
AJ007331-1|CAB42883.1| 484|Homo sapiens cysteine proteinase pro... 142 8e-34
AF132894-1|AAD41790.1| 484|Homo sapiens cathepsin F protein. 142 8e-34
AF088886-1|AAD26616.2| 484|Homo sapiens cathepsin F precursor p... 142 8e-34
AF071748-1|AAC78838.1| 338|Homo sapiens cathepsin F protein. 142 8e-34
AF136279-1|AAF13146.1| 484|Homo sapiens cathepsin F precursor p... 141 2e-33
CR541680-1|CAG46481.1| 338|Homo sapiens CTSF protein. 140 6e-33
AF071749-1|AAC78839.1| 302|Homo sapiens cathepsin F protein. 138 2e-32
X82153-1|CAA57649.1| 329|Homo sapiens Cathepsin O protein. 130 6e-30
U13665-1|AAA65233.1| 329|Homo sapiens cathepsin O protein. 130 6e-30
S79895-1|AAB35521.1| 329|Homo sapiens cathepsin O2 protein. 130 6e-30
CR541719-1|CAG46520.1| 329|Homo sapiens CTSK protein. 130 6e-30
CR541675-1|CAG46476.1| 329|Homo sapiens CTSK protein. 130 6e-30
BC016058-1|AAH16058.1| 329|Homo sapiens cathepsin K protein. 130 6e-30
AL356292-1|CAI13649.1| 329|Homo sapiens cathepsin K protein. 130 6e-30
AL355860-1|CAI12795.1| 329|Homo sapiens cathepsin K protein. 130 6e-30
U20280-1|AAA95998.1| 329|Homo sapiens cathepsin X protein. 127 4e-29
X16832-1|CAA34734.1| 335|Homo sapiens protein ( Human mRNA for ... 126 1e-28
BC002479-1|AAH02479.1| 335|Homo sapiens cathepsin H protein. 126 1e-28
AF426248-1|AAL23962.1| 323|Homo sapiens truncated cathepsin H p... 126 1e-28
AF426247-1|AAL23961.1| 335|Homo sapiens cathepsin H protein. 126 1e-28
CR456881-1|CAG33162.1| 335|Homo sapiens CTSH protein. 125 1e-28
CR541676-1|CAG46477.1| 331|Homo sapiens CTSS protein. 120 6e-27
BC002642-1|AAH02642.1| 331|Homo sapiens cathepsin S protein. 120 6e-27
AL356292-9|CAI13657.1| 331|Homo sapiens cathepsin S protein. 120 6e-27
U07374-1|AAB60643.2| 267|Homo sapiens cathepsin S protein. 119 1e-26
S93414-1|AAB22005.1| 331|Homo sapiens cathepsin S protein. 119 1e-26
M86553-1|AAA35655.1| 331|Homo sapiens cathepsin protein. 119 1e-26
M90696-1|AAC37592.1| 331|Homo sapiens cathepsin S protein. 118 1e-26
AL355860-2|CAI12796.1| 258|Homo sapiens cathepsin K protein. 117 3e-26
X77383-1|CAA54562.1| 321|Homo sapiens cathepsin O protein. 114 3e-25
BC049206-1|AAH49206.1| 321|Homo sapiens cathepsin O protein. 114 3e-25
X12451-1|CAA30981.1| 333|Homo sapiens pro-(cathepsin L) protein. 109 1e-23
M20496-1|AAA66974.1| 333|Homo sapiens CTSL protein. 109 1e-23
CR457053-1|CAG33334.1| 333|Homo sapiens CTSL protein. 109 1e-23
BC048255-1|AAH48255.1| 376|Homo sapiens cathepsin W protein. 109 1e-23
AL160279-3|CAI16308.1| 333|Homo sapiens cathepsin L1 protein. 109 1e-23
BC012612-1|AAH12612.1| 333|Homo sapiens cathepsin L1 protein. 108 2e-23
BC142983-1|AAI42984.1| 333|Homo sapiens cathepsin L1 protein. 108 2e-23
AF055903-1|AAC32181.1| 376|Homo sapiens cathepsin W protein. 107 5e-23
AF015954-1|AAB82457.1| 376|Homo sapiens lymphopain protein. 107 5e-23
AF013611-1|AAB82449.1| 376|Homo sapiens lymphopain protein. 107 5e-23
AL160279-2|CAI16307.1| 225|Homo sapiens cathepsin L1 protein. 103 6e-22
X07549-1|CAA30428.1| 248|Homo sapiens cathepsin H protein. 102 1e-21
Y14734-1|CAA75029.1| 334|Homo sapiens cathepsin L2 protein. 98 2e-20
Y18462-1|CAA77180.1| 175|Homo sapiens cathepsin L protein. 98 3e-20
BC110512-1|AAI10513.1| 334|Homo sapiens cathepsin L2 protein. 98 3e-20
BC023504-1|AAH23504.1| 334|Homo sapiens CTSL2 protein protein. 98 3e-20
AY358641-1|AAQ89004.1| 334|Homo sapiens cathepsin L2 protein. 98 3e-20
AL445670-2|CAI15053.1| 334|Homo sapiens cathepsin L2 protein. 98 3e-20
AF070448-1|AAC23598.1| 334|Homo sapiens cathepsin U protein. 98 3e-20
AB019534-1|BAA34365.1| 334|Homo sapiens cathepsin L2 protein. 98 3e-20
AB001928-1|BAA25909.1| 334|Homo sapiens cathepsin V protein. 98 3e-20
Y18461-1|CAA77179.1| 166|Homo sapiens cathepsin H protein. 83 9e-16
X87212-1|CAA60671.1| 463|Homo sapiens cathepsin C protein. 68 4e-11
U79415-1|AAC51341.1| 463|Homo sapiens prepro dipeptidyl peptida... 68 4e-11
AK223038-1|BAD96758.1| 463|Homo sapiens cathepsin C isoform a p... 68 4e-11
AF525032-1|AAQ08887.1| 463|Homo sapiens cathepsin C protein. 67 6e-11
AF234263-1|AAL48191.1| 463|Homo sapiens cathepsin C protein. 67 6e-11
AF234264-1|AAL48192.1| 463|Homo sapiens cathepsin C protein. 64 4e-10
AF254757-1|AAL48195.1| 463|Homo sapiens cathepsin C protein. 63 8e-10
X05256-1|CAA28877.1| 42|Homo sapiens protein ( Human mRNA frag... 54 5e-07
M14221-1|AAA52129.1| 339|Homo sapiens CTSB protein. 46 2e-04
L16510-1|AAC37547.1| 339|Homo sapiens cathepsin B protein. 46 2e-04
BC095408-1|AAH95408.1| 339|Homo sapiens cathepsin B protein. 46 2e-04
BC010240-1|AAH10240.1| 339|Homo sapiens cathepsin B protein. 46 2e-04
BC070278-1|AAH70278.1| 476|Homo sapiens tubulointerstitial neph... 42 0.003
AL589946-2|CAH70302.1| 476|Homo sapiens tubulointerstitial neph... 42 0.003
AL359380-5|CAI16272.1| 476|Homo sapiens tubulointerstitial neph... 42 0.003
AF195116-1|AAF08931.1| 476|Homo sapiens tubulointerstitial neph... 42 0.003
AB022277-1|BAA84949.1| 476|Homo sapiens tubulointerstitial neph... 42 0.003
Y18460-1|CAA77178.1| 195|Homo sapiens cathepsin B protein. 40 0.008
BT019915-1|AAV38718.1| 303|Homo sapiens cathepsin Z protein. 40 0.011
BC042168-1|AAH42168.1| 303|Homo sapiens cathepsin Z protein. 40 0.011
BC025419-1|AAH25419.1| 297|Homo sapiens CTSZ protein protein. 40 0.011
AL109840-6|CAC09370.1| 303|Homo sapiens cathepsin Z protein. 40 0.011
AF136276-1|AAF13148.1| 303|Homo sapiens cathepsin Z precursor p... 40 0.011
AF136273-1|AAF13145.1| 303|Homo sapiens cathepsin Z precursor p... 40 0.011
AF032906-1|AAC39839.1| 303|Homo sapiens cathepsin Z precursor p... 40 0.011
AF009923-1|AAC63141.1| 293|Homo sapiens preprocathepsin P protein. 40 0.011
AF073890-1|AAC61477.1| 303|Homo sapiens cathepsin X precursor p... 39 0.019
BC064633-1|AAH64633.1| 467|Homo sapiens tubulointerstitial neph... 37 0.058
AY358421-1|AAQ88787.1| 467|Homo sapiens LCN7 protein. 37 0.058
AK075398-1|BAC11596.1| 467|Homo sapiens protein ( Homo sapiens ... 37 0.058
AF236155-1|AAG40154.1| 467|Homo sapiens tubulointerstitial neph... 37 0.058
AF236150-1|AAG38876.1| 467|Homo sapiens tubulointerstitial neph... 37 0.058
AF205436-1|AAG33699.1| 467|Homo sapiens oxidized-LDL responsive... 37 0.058
AB050719-1|BAB18727.1| 467|Homo sapiens glucocorticoid-inducibl... 37 0.058
AB050716-1|BAB18636.1| 467|Homo sapiens glucocorticoid-inducibl... 37 0.058
AK074124-1|BAB84950.1| 284|Homo sapiens FLJ00196 protein protein. 33 0.72
AF217997-1|AAG17239.1| 151|Homo sapiens unknown protein. 32 2.2
BC089428-1|AAH89428.1| 1192|Homo sapiens PLEKHG1 protein protein. 31 5.0
AL450339-2|CAI12939.1| 1385|Homo sapiens pleckstrin homology dom... 31 5.0
AL035086-3|CAI42790.1| 1385|Homo sapiens pleckstrin homology dom... 31 5.0
AB033035-1|BAA86523.1| 1113|Homo sapiens KIAA1209 protein protein. 31 5.0
BX640701-1|CAE45821.1| 477|Homo sapiens hypothetical protein pr... 30 8.8
BC090041-1|AAH90041.1| 477|Homo sapiens ZWILCH protein protein. 30 8.8
BC036900-1|AAH36900.1| 477|Homo sapiens ZWILCH protein protein. 30 8.8
AK023175-1|BAB14446.1| 591|Homo sapiens protein ( Homo sapiens ... 30 8.8
AK000898-1|BAA91414.1| 134|Homo sapiens protein ( Homo sapiens ... 30 8.8
>BC036451-1|AAH36451.1| 484|Homo sapiens cathepsin F protein.
Length = 484
Score = 142 bits (345), Expect = 8e-34
Identities = 70/195 (35%), Positives = 110/195 (56%), Gaps = 2/195 (1%)
Frame = +2
Query: 92 PLKAPNYFEEFVHRFNKNYSSEVEKLRRFKIFQHNL--NEIINKNQNDSAKYEINKFSDL 265
P+K + F+ FV +N+ Y S+ E R +F +N+ + I +A+Y + KFSDL
Sbjct: 180 PVKMASIFKNFVITYNRTYESKEEARWRLSVFVNNMVRAQKIQALDRGTAQYGVTKFSDL 239
Query: 266 SKDETIAKYTGLSLPTQTQNFCKVILLDQPPGKGPLEFDWRRLNKVTSVKNQGMCGACWA 445
+++E Y L + N K+ P E+DWR VT VK+QGMCG+CWA
Sbjct: 240 TEEEFRTIYLNTLLRKEPGN--KMKQAKSVGDLAPPEWDWRSKGAVTKVKDQGMCGSCWA 297
Query: 446 FATLGSLESQFAIKHNELINLSEQQMIDCDFVDAGCNGGLLHTAFEAIIKMGGVQLESDY 625
F+ G++E Q+ + L++LSEQ+++DCD +D C GGL A+ AI +GG++ E DY
Sbjct: 298 FSVTGNVEGQWFLNQGTLLSLSEQELLDCDKMDKACMGGLPSNAYSAIKNLGGLETEDDY 357
Query: 626 PYEADNNNCRMNSNK 670
Y+ +C ++ K
Sbjct: 358 SYQGHMQSCNFSAEK 372
>BC011682-1|AAH11682.1| 484|Homo sapiens cathepsin F protein.
Length = 484
Score = 142 bits (345), Expect = 8e-34
Identities = 70/195 (35%), Positives = 110/195 (56%), Gaps = 2/195 (1%)
Frame = +2
Query: 92 PLKAPNYFEEFVHRFNKNYSSEVEKLRRFKIFQHNL--NEIINKNQNDSAKYEINKFSDL 265
P+K + F+ FV +N+ Y S+ E R +F +N+ + I +A+Y + KFSDL
Sbjct: 180 PVKMASIFKNFVITYNRTYESKEEARWRLSVFVNNMVRAQKIQALDRGTAQYGVTKFSDL 239
Query: 266 SKDETIAKYTGLSLPTQTQNFCKVILLDQPPGKGPLEFDWRRLNKVTSVKNQGMCGACWA 445
+++E Y L + N K+ P E+DWR VT VK+QGMCG+CWA
Sbjct: 240 TEEEFRTIYLNTLLRKEPGN--KMKQAKSVGDLAPPEWDWRSKGAVTKVKDQGMCGSCWA 297
Query: 446 FATLGSLESQFAIKHNELINLSEQQMIDCDFVDAGCNGGLLHTAFEAIIKMGGVQLESDY 625
F+ G++E Q+ + L++LSEQ+++DCD +D C GGL A+ AI +GG++ E DY
Sbjct: 298 FSVTGNVEGQWFLNQGTLLSLSEQELLDCDKMDKACMGGLPSNAYSAIKNLGGLETEDDY 357
Query: 626 PYEADNNNCRMNSNK 670
Y+ +C ++ K
Sbjct: 358 SYQGHMQSCNFSAEK 372
>AL137742-1|CAB70900.1| 308|Homo sapiens hypothetical protein
protein.
Length = 308
Score = 142 bits (345), Expect = 8e-34
Identities = 70/195 (35%), Positives = 110/195 (56%), Gaps = 2/195 (1%)
Frame = +2
Query: 92 PLKAPNYFEEFVHRFNKNYSSEVEKLRRFKIFQHNL--NEIINKNQNDSAKYEINKFSDL 265
P+K + F+ FV +N+ Y S+ E R +F +N+ + I +A+Y + KFSDL
Sbjct: 20 PVKMASIFKNFVITYNRTYESKEEARWRLSVFVNNMVRAQKIQALDRGTAQYGVTKFSDL 79
Query: 266 SKDETIAKYTGLSLPTQTQNFCKVILLDQPPGKGPLEFDWRRLNKVTSVKNQGMCGACWA 445
+++E Y L + N K+ P E+DWR VT VK+QGMCG+CWA
Sbjct: 80 TEEEFRTIYLNTLLRKEPGN--KMKQAKSVGDLAPPEWDWRSKGAVTKVKDQGMCGSCWA 137
Query: 446 FATLGSLESQFAIKHNELINLSEQQMIDCDFVDAGCNGGLLHTAFEAIIKMGGVQLESDY 625
F+ G++E Q+ + L++LSEQ+++DCD +D C GGL A+ AI +GG++ E DY
Sbjct: 138 FSVTGNVEGQWFLNQGTLLSLSEQELLDCDKMDKACMGGLPSNAYSAIKNLGGLETEDDY 197
Query: 626 PYEADNNNCRMNSNK 670
Y+ +C ++ K
Sbjct: 198 SYQGHMQSCNFSAEK 212
>AJ007331-1|CAB42883.1| 484|Homo sapiens cysteine proteinase
protein.
Length = 484
Score = 142 bits (345), Expect = 8e-34
Identities = 70/195 (35%), Positives = 110/195 (56%), Gaps = 2/195 (1%)
Frame = +2
Query: 92 PLKAPNYFEEFVHRFNKNYSSEVEKLRRFKIFQHNL--NEIINKNQNDSAKYEINKFSDL 265
P+K + F+ FV +N+ Y S+ E R +F +N+ + I +A+Y + KFSDL
Sbjct: 180 PVKMASIFKNFVITYNRTYESKEEARWRLSVFVNNMVRAQKIQALDRGTAQYGVTKFSDL 239
Query: 266 SKDETIAKYTGLSLPTQTQNFCKVILLDQPPGKGPLEFDWRRLNKVTSVKNQGMCGACWA 445
+++E Y L + N K+ P E+DWR VT VK+QGMCG+CWA
Sbjct: 240 TEEEFRTIYLNTLLRKEPGN--KMKQAKSVGDLAPPEWDWRSKGAVTKVKDQGMCGSCWA 297
Query: 446 FATLGSLESQFAIKHNELINLSEQQMIDCDFVDAGCNGGLLHTAFEAIIKMGGVQLESDY 625
F+ G++E Q+ + L++LSEQ+++DCD +D C GGL A+ AI +GG++ E DY
Sbjct: 298 FSVTGNVEGQWFLNQGTLLSLSEQELLDCDKMDKACMGGLPSNAYSAIKNLGGLETEDDY 357
Query: 626 PYEADNNNCRMNSNK 670
Y+ +C ++ K
Sbjct: 358 SYQGHMQSCNFSAEK 372
>AF132894-1|AAD41790.1| 484|Homo sapiens cathepsin F protein.
Length = 484
Score = 142 bits (345), Expect = 8e-34
Identities = 70/195 (35%), Positives = 110/195 (56%), Gaps = 2/195 (1%)
Frame = +2
Query: 92 PLKAPNYFEEFVHRFNKNYSSEVEKLRRFKIFQHNL--NEIINKNQNDSAKYEINKFSDL 265
P+K + F+ FV +N+ Y S+ E R +F +N+ + I +A+Y + KFSDL
Sbjct: 180 PVKMASIFKNFVITYNRTYESKEEARWRLSVFVNNMVRAQKIQALDRGTAQYGVTKFSDL 239
Query: 266 SKDETIAKYTGLSLPTQTQNFCKVILLDQPPGKGPLEFDWRRLNKVTSVKNQGMCGACWA 445
+++E Y L + N K+ P E+DWR VT VK+QGMCG+CWA
Sbjct: 240 TEEEFRTIYLNTLLRKEPGN--KMKQAKSVGDLAPPEWDWRSKGAVTKVKDQGMCGSCWA 297
Query: 446 FATLGSLESQFAIKHNELINLSEQQMIDCDFVDAGCNGGLLHTAFEAIIKMGGVQLESDY 625
F+ G++E Q+ + L++LSEQ+++DCD +D C GGL A+ AI +GG++ E DY
Sbjct: 298 FSVTGNVEGQWFLNQGTLLSLSEQELLDCDKMDKACMGGLPSNAYSAIKNLGGLETEDDY 357
Query: 626 PYEADNNNCRMNSNK 670
Y+ +C ++ K
Sbjct: 358 SYQGHMQSCNFSAEK 372
>AF088886-1|AAD26616.2| 484|Homo sapiens cathepsin F precursor
protein.
Length = 484
Score = 142 bits (345), Expect = 8e-34
Identities = 70/195 (35%), Positives = 110/195 (56%), Gaps = 2/195 (1%)
Frame = +2
Query: 92 PLKAPNYFEEFVHRFNKNYSSEVEKLRRFKIFQHNL--NEIINKNQNDSAKYEINKFSDL 265
P+K + F+ FV +N+ Y S+ E R +F +N+ + I +A+Y + KFSDL
Sbjct: 180 PVKMASIFKNFVITYNRTYESKEEARWRLSVFVNNMVRAQKIQALDRGTAQYGVTKFSDL 239
Query: 266 SKDETIAKYTGLSLPTQTQNFCKVILLDQPPGKGPLEFDWRRLNKVTSVKNQGMCGACWA 445
+++E Y L + N K+ P E+DWR VT VK+QGMCG+CWA
Sbjct: 240 TEEEFRTIYLNTLLRKEPGN--KMKQAKSVGDLAPPEWDWRSKGAVTKVKDQGMCGSCWA 297
Query: 446 FATLGSLESQFAIKHNELINLSEQQMIDCDFVDAGCNGGLLHTAFEAIIKMGGVQLESDY 625
F+ G++E Q+ + L++LSEQ+++DCD +D C GGL A+ AI +GG++ E DY
Sbjct: 298 FSVTGNVEGQWFLNQGTLLSLSEQELLDCDKMDKACMGGLPSNAYSAIKNLGGLETEDDY 357
Query: 626 PYEADNNNCRMNSNK 670
Y+ +C ++ K
Sbjct: 358 SYQGHMQSCNFSAEK 372
>AF071748-1|AAC78838.1| 338|Homo sapiens cathepsin F protein.
Length = 338
Score = 142 bits (345), Expect = 8e-34
Identities = 70/195 (35%), Positives = 110/195 (56%), Gaps = 2/195 (1%)
Frame = +2
Query: 92 PLKAPNYFEEFVHRFNKNYSSEVEKLRRFKIFQHNL--NEIINKNQNDSAKYEINKFSDL 265
P+K + F+ FV +N+ Y S+ E R +F +N+ + I +A+Y + KFSDL
Sbjct: 34 PVKMASIFKNFVITYNRTYESKEEARWRLSVFVNNMVRAQKIQALDRGTAQYGVTKFSDL 93
Query: 266 SKDETIAKYTGLSLPTQTQNFCKVILLDQPPGKGPLEFDWRRLNKVTSVKNQGMCGACWA 445
+++E Y L + N K+ P E+DWR VT VK+QGMCG+CWA
Sbjct: 94 TEEEFRTIYLNTLLRKEPGN--KMKQAKSVGDLAPPEWDWRSKGAVTKVKDQGMCGSCWA 151
Query: 446 FATLGSLESQFAIKHNELINLSEQQMIDCDFVDAGCNGGLLHTAFEAIIKMGGVQLESDY 625
F+ G++E Q+ + L++LSEQ+++DCD +D C GGL A+ AI +GG++ E DY
Sbjct: 152 FSVTGNVEGQWFLNQGTLLSLSEQELLDCDKMDKACMGGLPSNAYSAIKNLGGLETEDDY 211
Query: 626 PYEADNNNCRMNSNK 670
Y+ +C ++ K
Sbjct: 212 SYQGHMQSCNFSAEK 226
>AF136279-1|AAF13146.1| 484|Homo sapiens cathepsin F precursor
protein.
Length = 484
Score = 141 bits (341), Expect = 2e-33
Identities = 69/195 (35%), Positives = 110/195 (56%), Gaps = 2/195 (1%)
Frame = +2
Query: 92 PLKAPNYFEEFVHRFNKNYSSEVEKLRRFKIFQHNL--NEIINKNQNDSAKYEINKFSDL 265
P+K + F+ FV +N+ Y S+ E R +F +N+ + I +A+Y + KFSDL
Sbjct: 180 PVKMASIFKNFVITYNRTYESKEEARWRLSVFVNNMVRAQKIQALDRGTAQYGVTKFSDL 239
Query: 266 SKDETIAKYTGLSLPTQTQNFCKVILLDQPPGKGPLEFDWRRLNKVTSVKNQGMCGACWA 445
+++E Y L + N K+ P E+DWR VT VK+QGMCG+CWA
Sbjct: 240 TEEEFRTIYLNTLLRKEPGN--KMKQAKSVGDLAPPEWDWRSKGAVTKVKDQGMCGSCWA 297
Query: 446 FATLGSLESQFAIKHNELINLSEQQMIDCDFVDAGCNGGLLHTAFEAIIKMGGVQLESDY 625
F+ G+++ Q+ + L++LSEQ+++DCD +D C GGL A+ AI +GG++ E DY
Sbjct: 298 FSVTGNVKGQWFLNQGTLLSLSEQELLDCDKMDKACMGGLPSNAYSAIKNLGGLETEDDY 357
Query: 626 PYEADNNNCRMNSNK 670
Y+ +C ++ K
Sbjct: 358 SYQGHMQSCNFSAEK 372
>CR541680-1|CAG46481.1| 338|Homo sapiens CTSF protein.
Length = 338
Score = 140 bits (338), Expect = 6e-33
Identities = 69/195 (35%), Positives = 109/195 (55%), Gaps = 2/195 (1%)
Frame = +2
Query: 92 PLKAPNYFEEFVHRFNKNYSSEVEKLRRFKIFQHNL--NEIINKNQNDSAKYEINKFSDL 265
P+K + F+ FV +N+ Y S+ E R +F +N+ + I +A+Y + KFSDL
Sbjct: 34 PVKMASIFKNFVITYNRTYESKEEARWRLSVFVNNMVRAQKIQALDRGTAQYGVTKFSDL 93
Query: 266 SKDETIAKYTGLSLPTQTQNFCKVILLDQPPGKGPLEFDWRRLNKVTSVKNQGMCGACWA 445
+++E Y L + N K+ P E+DWR VT VK+QGMCG+CWA
Sbjct: 94 TEEEFRTIYLNTLLRKEPGN--KMKQAKSVGDLAPPEWDWRSKGAVTKVKDQGMCGSCWA 151
Query: 446 FATLGSLESQFAIKHNELINLSEQQMIDCDFVDAGCNGGLLHTAFEAIIKMGGVQLESDY 625
F+ G++E Q+ + L++LSEQ+++DCD +D C GGL A+ AI +GG++ DY
Sbjct: 152 FSVTGNVEGQWFLNQGTLLSLSEQELLDCDKMDKACMGGLPSNAYSAIKNLGGLETVDDY 211
Query: 626 PYEADNNNCRMNSNK 670
Y+ +C ++ K
Sbjct: 212 SYQGHMQSCNFSAEK 226
>AF071749-1|AAC78839.1| 302|Homo sapiens cathepsin F protein.
Length = 302
Score = 138 bits (334), Expect = 2e-32
Identities = 68/188 (36%), Positives = 106/188 (56%), Gaps = 2/188 (1%)
Frame = +2
Query: 113 FEEFVHRFNKNYSSEVEKLRRFKIFQHNL--NEIINKNQNDSAKYEINKFSDLSKDETIA 286
F+ FV +N+ Y S+ E R +F +N+ + I +A+Y + KFSDL+++E
Sbjct: 5 FKNFVITYNRTYESKEEARWRLSVFVNNMVRAQKIQALDRGTAQYGVTKFSDLTEEEFRT 64
Query: 287 KYTGLSLPTQTQNFCKVILLDQPPGKGPLEFDWRRLNKVTSVKNQGMCGACWAFATLGSL 466
Y L + N K+ P E+DWR VT VK+QGMCG+CWAF+ G++
Sbjct: 65 IYLNTLLRKEPGN--KMKQAKSVGDLAPPEWDWRSKGAVTKVKDQGMCGSCWAFSVTGNV 122
Query: 467 ESQFAIKHNELINLSEQQMIDCDFVDAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNN 646
E Q+ + L++LSEQ+++DCD +D C GGL A+ AI +GG++ E DY Y+
Sbjct: 123 EGQWFLNQGTLLSLSEQELLDCDKMDKACMGGLPSNAYSAIKNLGGLETEDDYSYQGHMQ 182
Query: 647 NCRMNSNK 670
+C ++ K
Sbjct: 183 SCNFSAEK 190
>X82153-1|CAA57649.1| 329|Homo sapiens Cathepsin O protein.
Length = 329
Score = 130 bits (313), Expect = 6e-30
Identities = 68/203 (33%), Positives = 106/203 (52%), Gaps = 5/203 (2%)
Frame = +2
Query: 68 VVKSAAYDPLKAPNYFEEFVHRFNKNYSSEVEKLRRFKIFQHNLNEIINKNQNDSA---K 238
VV A Y ++E + K Y+++V+++ R I++ NL I N S
Sbjct: 11 VVSFALYPEEILDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHT 70
Query: 239 YEI--NKFSDLSKDETIAKYTGLSLPTQTQNFCKVILLDQPPGKGPLEFDWRRLNKVTSV 412
YE+ N D++ +E + K TGL +P + + + G+ P D+R+ VT V
Sbjct: 71 YELAMNHLGDMTSEEVVQKMTGLKVPLSHSRSNDTLYIPEWEGRAPDSVDYRKKGYVTPV 130
Query: 413 KNQGMCGACWAFATLGSLESQFAIKHNELINLSEQQMIDCDFVDAGCNGGLLHTAFEAII 592
KNQG CG+CWAF+++G+LE Q K +L+NLS Q ++DC + GC GG + AF+ +
Sbjct: 131 KNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQ 190
Query: 593 KMGGVQLESDYPYEADNNNCRMN 661
K G+ E YPY +C N
Sbjct: 191 KNRGIDSEDAYPYVGQEESCMYN 213
>U13665-1|AAA65233.1| 329|Homo sapiens cathepsin O protein.
Length = 329
Score = 130 bits (313), Expect = 6e-30
Identities = 68/203 (33%), Positives = 106/203 (52%), Gaps = 5/203 (2%)
Frame = +2
Query: 68 VVKSAAYDPLKAPNYFEEFVHRFNKNYSSEVEKLRRFKIFQHNLNEIINKNQNDSA---K 238
VV A Y ++E + K Y+++V+++ R I++ NL I N S
Sbjct: 11 VVSFALYPEEILDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHT 70
Query: 239 YEI--NKFSDLSKDETIAKYTGLSLPTQTQNFCKVILLDQPPGKGPLEFDWRRLNKVTSV 412
YE+ N D++ +E + K TGL +P + + + G+ P D+R+ VT V
Sbjct: 71 YELAMNHLGDMTSEEVVQKMTGLKVPLSHSRSNDTLYIPEWEGRAPDSVDYRKKGYVTPV 130
Query: 413 KNQGMCGACWAFATLGSLESQFAIKHNELINLSEQQMIDCDFVDAGCNGGLLHTAFEAII 592
KNQG CG+CWAF+++G+LE Q K +L+NLS Q ++DC + GC GG + AF+ +
Sbjct: 131 KNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQ 190
Query: 593 KMGGVQLESDYPYEADNNNCRMN 661
K G+ E YPY +C N
Sbjct: 191 KNRGIDSEDAYPYVGQEESCMYN 213
>S79895-1|AAB35521.1| 329|Homo sapiens cathepsin O2 protein.
Length = 329
Score = 130 bits (313), Expect = 6e-30
Identities = 68/203 (33%), Positives = 106/203 (52%), Gaps = 5/203 (2%)
Frame = +2
Query: 68 VVKSAAYDPLKAPNYFEEFVHRFNKNYSSEVEKLRRFKIFQHNLNEIINKNQNDSA---K 238
VV A Y ++E + K Y+++V+++ R I++ NL I N S
Sbjct: 11 VVSFALYPEEILDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHT 70
Query: 239 YEI--NKFSDLSKDETIAKYTGLSLPTQTQNFCKVILLDQPPGKGPLEFDWRRLNKVTSV 412
YE+ N D++ +E + K TGL +P + + + G+ P D+R+ VT V
Sbjct: 71 YELAMNHLGDMTSEEVVQKMTGLKVPLSHSRSNDTLYIPEWEGRAPDSVDYRKKGYVTPV 130
Query: 413 KNQGMCGACWAFATLGSLESQFAIKHNELINLSEQQMIDCDFVDAGCNGGLLHTAFEAII 592
KNQG CG+CWAF+++G+LE Q K +L+NLS Q ++DC + GC GG + AF+ +
Sbjct: 131 KNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQ 190
Query: 593 KMGGVQLESDYPYEADNNNCRMN 661
K G+ E YPY +C N
Sbjct: 191 KNRGIDSEDAYPYVGQEESCMYN 213
>CR541719-1|CAG46520.1| 329|Homo sapiens CTSK protein.
Length = 329
Score = 130 bits (313), Expect = 6e-30
Identities = 68/203 (33%), Positives = 106/203 (52%), Gaps = 5/203 (2%)
Frame = +2
Query: 68 VVKSAAYDPLKAPNYFEEFVHRFNKNYSSEVEKLRRFKIFQHNLNEIINKNQNDSA---K 238
VV A Y ++E + K Y+++V+++ R I++ NL I N S
Sbjct: 11 VVSLALYPEEILDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHT 70
Query: 239 YEI--NKFSDLSKDETIAKYTGLSLPTQTQNFCKVILLDQPPGKGPLEFDWRRLNKVTSV 412
YE+ N D++ +E + K TGL +P + + + G+ P D+R+ VT V
Sbjct: 71 YELAMNHLGDMTSEEVVQKMTGLKVPLSHSRSNDTLYIPEWEGRAPDSVDYRKKGYVTPV 130
Query: 413 KNQGMCGACWAFATLGSLESQFAIKHNELINLSEQQMIDCDFVDAGCNGGLLHTAFEAII 592
KNQG CG+CWAF+++G+LE Q K +L+NLS Q ++DC + GC GG + AF+ +
Sbjct: 131 KNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQ 190
Query: 593 KMGGVQLESDYPYEADNNNCRMN 661
K G+ E YPY +C N
Sbjct: 191 KNRGIDSEDAYPYVGQEESCMYN 213
>CR541675-1|CAG46476.1| 329|Homo sapiens CTSK protein.
Length = 329
Score = 130 bits (313), Expect = 6e-30
Identities = 68/203 (33%), Positives = 106/203 (52%), Gaps = 5/203 (2%)
Frame = +2
Query: 68 VVKSAAYDPLKAPNYFEEFVHRFNKNYSSEVEKLRRFKIFQHNLNEIINKNQNDSA---K 238
VV A Y ++E + K Y+++V+++ R I++ NL I N S
Sbjct: 11 VVSFALYPEEILDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHT 70
Query: 239 YEI--NKFSDLSKDETIAKYTGLSLPTQTQNFCKVILLDQPPGKGPLEFDWRRLNKVTSV 412
YE+ N D++ +E + K TGL +P + + + G+ P D+R+ VT V
Sbjct: 71 YELAMNHLGDMTSEEVVQKMTGLKVPLSHSRSNDTLYIPEWEGRAPDSVDYRKKGYVTPV 130
Query: 413 KNQGMCGACWAFATLGSLESQFAIKHNELINLSEQQMIDCDFVDAGCNGGLLHTAFEAII 592
KNQG CG+CWAF+++G+LE Q K +L+NLS Q ++DC + GC GG + AF+ +
Sbjct: 131 KNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQ 190
Query: 593 KMGGVQLESDYPYEADNNNCRMN 661
K G+ E YPY +C N
Sbjct: 191 KNRGIDSEDAYPYVGQEESCMYN 213
>BC016058-1|AAH16058.1| 329|Homo sapiens cathepsin K protein.
Length = 329
Score = 130 bits (313), Expect = 6e-30
Identities = 68/203 (33%), Positives = 106/203 (52%), Gaps = 5/203 (2%)
Frame = +2
Query: 68 VVKSAAYDPLKAPNYFEEFVHRFNKNYSSEVEKLRRFKIFQHNLNEIINKNQNDSA---K 238
VV A Y ++E + K Y+++V+++ R I++ NL I N S
Sbjct: 11 VVSFALYPEEILDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHT 70
Query: 239 YEI--NKFSDLSKDETIAKYTGLSLPTQTQNFCKVILLDQPPGKGPLEFDWRRLNKVTSV 412
YE+ N D++ +E + K TGL +P + + + G+ P D+R+ VT V
Sbjct: 71 YELAMNHLGDMTSEEVVQKMTGLKVPLSHSRSNDTLYIPEWEGRAPDSVDYRKKGYVTPV 130
Query: 413 KNQGMCGACWAFATLGSLESQFAIKHNELINLSEQQMIDCDFVDAGCNGGLLHTAFEAII 592
KNQG CG+CWAF+++G+LE Q K +L+NLS Q ++DC + GC GG + AF+ +
Sbjct: 131 KNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQ 190
Query: 593 KMGGVQLESDYPYEADNNNCRMN 661
K G+ E YPY +C N
Sbjct: 191 KNRGIDSEDAYPYVGQEESCMYN 213
>AL356292-1|CAI13649.1| 329|Homo sapiens cathepsin K protein.
Length = 329
Score = 130 bits (313), Expect = 6e-30
Identities = 68/203 (33%), Positives = 106/203 (52%), Gaps = 5/203 (2%)
Frame = +2
Query: 68 VVKSAAYDPLKAPNYFEEFVHRFNKNYSSEVEKLRRFKIFQHNLNEIINKNQNDSA---K 238
VV A Y ++E + K Y+++V+++ R I++ NL I N S
Sbjct: 11 VVSFALYPEEILDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHT 70
Query: 239 YEI--NKFSDLSKDETIAKYTGLSLPTQTQNFCKVILLDQPPGKGPLEFDWRRLNKVTSV 412
YE+ N D++ +E + K TGL +P + + + G+ P D+R+ VT V
Sbjct: 71 YELAMNHLGDMTSEEVVQKMTGLKVPLSHSRSNDTLYIPEWEGRAPDSVDYRKKGYVTPV 130
Query: 413 KNQGMCGACWAFATLGSLESQFAIKHNELINLSEQQMIDCDFVDAGCNGGLLHTAFEAII 592
KNQG CG+CWAF+++G+LE Q K +L+NLS Q ++DC + GC GG + AF+ +
Sbjct: 131 KNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQ 190
Query: 593 KMGGVQLESDYPYEADNNNCRMN 661
K G+ E YPY +C N
Sbjct: 191 KNRGIDSEDAYPYVGQEESCMYN 213
>AL355860-1|CAI12795.1| 329|Homo sapiens cathepsin K protein.
Length = 329
Score = 130 bits (313), Expect = 6e-30
Identities = 68/203 (33%), Positives = 106/203 (52%), Gaps = 5/203 (2%)
Frame = +2
Query: 68 VVKSAAYDPLKAPNYFEEFVHRFNKNYSSEVEKLRRFKIFQHNLNEIINKNQNDSA---K 238
VV A Y ++E + K Y+++V+++ R I++ NL I N S
Sbjct: 11 VVSFALYPEEILDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHT 70
Query: 239 YEI--NKFSDLSKDETIAKYTGLSLPTQTQNFCKVILLDQPPGKGPLEFDWRRLNKVTSV 412
YE+ N D++ +E + K TGL +P + + + G+ P D+R+ VT V
Sbjct: 71 YELAMNHLGDMTSEEVVQKMTGLKVPLSHSRSNDTLYIPEWEGRAPDSVDYRKKGYVTPV 130
Query: 413 KNQGMCGACWAFATLGSLESQFAIKHNELINLSEQQMIDCDFVDAGCNGGLLHTAFEAII 592
KNQG CG+CWAF+++G+LE Q K +L+NLS Q ++DC + GC GG + AF+ +
Sbjct: 131 KNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQ 190
Query: 593 KMGGVQLESDYPYEADNNNCRMN 661
K G+ E YPY +C N
Sbjct: 191 KNRGIDSEDAYPYVGQEESCMYN 213
>U20280-1|AAA95998.1| 329|Homo sapiens cathepsin X protein.
Length = 329
Score = 127 bits (306), Expect = 4e-29
Identities = 67/203 (33%), Positives = 105/203 (51%), Gaps = 5/203 (2%)
Frame = +2
Query: 68 VVKSAAYDPLKAPNYFEEFVHRFNKNYSSEVEKLRRFKIFQHNLNEIINKNQNDSA---K 238
VV A Y ++E + K Y+++V+++ I++ NL I N S
Sbjct: 11 VVSFALYPEEILDTHWELWKKTHRKQYNNKVDEISPRLIWEKNLKYISIHNLEASLGVHT 70
Query: 239 YEI--NKFSDLSKDETIAKYTGLSLPTQTQNFCKVILLDQPPGKGPLEFDWRRLNKVTSV 412
YE+ N D++ +E + K TGL +P + + + G+ P D+R+ VT V
Sbjct: 71 YELAMNHLGDMTSEEVVQKMTGLKVPLSHSRSNDTLYIPEWEGRAPDSVDYRKKGYVTPV 130
Query: 413 KNQGMCGACWAFATLGSLESQFAIKHNELINLSEQQMIDCDFVDAGCNGGLLHTAFEAII 592
KNQG CG+CWAF+++G+LE Q K +L+NLS Q ++DC + GC GG + AF+ +
Sbjct: 131 KNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQ 190
Query: 593 KMGGVQLESDYPYEADNNNCRMN 661
K G+ E YPY +C N
Sbjct: 191 KNRGIDSEDAYPYVGQEESCMYN 213
>X16832-1|CAA34734.1| 335|Homo sapiens protein ( Human mRNA for
cathepsin H (EC 3.4.22.16). ).
Length = 335
Score = 126 bits (303), Expect = 1e-28
Identities = 74/193 (38%), Positives = 108/193 (55%), Gaps = 6/193 (3%)
Frame = +2
Query: 110 YFEEFVHRFNKNYSSEVEKLRRFKIFQHNLNEI-INKNQNDSAKYEINKFSDLSKDETIA 286
+F+ ++ + K YS+E E R + F N +I + N N + K +N+FSD+S E
Sbjct: 34 HFKSWMSKHRKTYSTE-EYHHRLQTFASNWRKINAHNNGNHTFKMALNQFSDMSFAEIKH 92
Query: 287 KYTGLSLPTQTQNFCKVILLDQPPGKGPL--EFDWRRL-NKVTSVKNQGMCGACWAFATL 457
KY L ++ QN C + G GP DWR+ N V+ VKNQG CG+CW F+T
Sbjct: 93 KY----LWSEPQN-CSATKSNYLRGTGPYPPSVDWRKKGNFVSPVKNQGACGSCWTFSTT 147
Query: 458 GSLESQFAIKHNELINLSEQQMIDC--DFVDAGCNGGLLHTAFEAIIKMGGVQLESDYPY 631
G+LES AI ++++L+EQQ++DC DF + GC GGL AFE I+ G+ E YPY
Sbjct: 148 GALESAIAIATGKMLSLAEQQLVDCAQDFNNYGCQGGLPSQAFEYILYNKGIMGEDTYPY 207
Query: 632 EADNNNCRMNSNK 670
+ + C+ K
Sbjct: 208 QGKDGYCKFQPGK 220
>BC002479-1|AAH02479.1| 335|Homo sapiens cathepsin H protein.
Length = 335
Score = 126 bits (303), Expect = 1e-28
Identities = 74/193 (38%), Positives = 108/193 (55%), Gaps = 6/193 (3%)
Frame = +2
Query: 110 YFEEFVHRFNKNYSSEVEKLRRFKIFQHNLNEI-INKNQNDSAKYEINKFSDLSKDETIA 286
+F+ ++ + K YS+E E R + F N +I + N N + K +N+FSD+S E
Sbjct: 34 HFKSWMSKHRKTYSTE-EYHHRLQTFASNWRKINAHNNGNHTFKMALNQFSDMSFAEIKH 92
Query: 287 KYTGLSLPTQTQNFCKVILLDQPPGKGPL--EFDWRRL-NKVTSVKNQGMCGACWAFATL 457
KY L ++ QN C + G GP DWR+ N V+ VKNQG CG+CW F+T
Sbjct: 93 KY----LWSEPQN-CSATKSNYLRGTGPYPPSVDWRKKGNFVSPVKNQGACGSCWTFSTT 147
Query: 458 GSLESQFAIKHNELINLSEQQMIDC--DFVDAGCNGGLLHTAFEAIIKMGGVQLESDYPY 631
G+LES AI ++++L+EQQ++DC DF + GC GGL AFE I+ G+ E YPY
Sbjct: 148 GALESAIAIATGKMLSLAEQQLVDCAQDFNNHGCQGGLPSQAFEYILYNKGIMGEDTYPY 207
Query: 632 EADNNNCRMNSNK 670
+ + C+ K
Sbjct: 208 QGKDGYCKFQPGK 220
>AF426248-1|AAL23962.1| 323|Homo sapiens truncated cathepsin H
protein.
Length = 323
Score = 126 bits (303), Expect = 1e-28
Identities = 74/193 (38%), Positives = 108/193 (55%), Gaps = 6/193 (3%)
Frame = +2
Query: 110 YFEEFVHRFNKNYSSEVEKLRRFKIFQHNLNEI-INKNQNDSAKYEINKFSDLSKDETIA 286
+F+ ++ + K YS+E E R + F N +I + N N + K +N+FSD+S E
Sbjct: 22 HFKSWMSKHRKTYSTE-EYHHRLQTFASNWRKINAHNNGNHTFKMALNQFSDMSFAEIKH 80
Query: 287 KYTGLSLPTQTQNFCKVILLDQPPGKGPL--EFDWRRL-NKVTSVKNQGMCGACWAFATL 457
KY L ++ QN C + G GP DWR+ N V+ VKNQG CG+CW F+T
Sbjct: 81 KY----LWSEPQN-CSATKSNYLRGTGPYPPSVDWRKKGNFVSPVKNQGACGSCWTFSTT 135
Query: 458 GSLESQFAIKHNELINLSEQQMIDC--DFVDAGCNGGLLHTAFEAIIKMGGVQLESDYPY 631
G+LES AI ++++L+EQQ++DC DF + GC GGL AFE I+ G+ E YPY
Sbjct: 136 GALESAIAIATGKMLSLAEQQLVDCAQDFNNYGCQGGLPSQAFEYILYNKGIMGEDTYPY 195
Query: 632 EADNNNCRMNSNK 670
+ + C+ K
Sbjct: 196 QGKDGYCKFQPGK 208
>AF426247-1|AAL23961.1| 335|Homo sapiens cathepsin H protein.
Length = 335
Score = 126 bits (303), Expect = 1e-28
Identities = 74/193 (38%), Positives = 108/193 (55%), Gaps = 6/193 (3%)
Frame = +2
Query: 110 YFEEFVHRFNKNYSSEVEKLRRFKIFQHNLNEI-INKNQNDSAKYEINKFSDLSKDETIA 286
+F+ ++ + K YS+E E R + F N +I + N N + K +N+FSD+S E
Sbjct: 34 HFKSWMSKHRKTYSTE-EYHHRLQTFASNWRKINAHNNGNHTFKMALNQFSDMSFAEIKH 92
Query: 287 KYTGLSLPTQTQNFCKVILLDQPPGKGPL--EFDWRRL-NKVTSVKNQGMCGACWAFATL 457
KY L ++ QN C + G GP DWR+ N V+ VKNQG CG+CW F+T
Sbjct: 93 KY----LWSEPQN-CSATKSNYLRGTGPYPPSVDWRKKGNFVSPVKNQGACGSCWTFSTT 147
Query: 458 GSLESQFAIKHNELINLSEQQMIDC--DFVDAGCNGGLLHTAFEAIIKMGGVQLESDYPY 631
G+LES AI ++++L+EQQ++DC DF + GC GGL AFE I+ G+ E YPY
Sbjct: 148 GALESAIAIATGKMLSLAEQQLVDCAQDFNNYGCQGGLPSQAFEYILYNKGIMGEDTYPY 207
Query: 632 EADNNNCRMNSNK 670
+ + C+ K
Sbjct: 208 QGKDGYCKFQPGK 220
>CR456881-1|CAG33162.1| 335|Homo sapiens CTSH protein.
Length = 335
Score = 125 bits (302), Expect = 1e-28
Identities = 74/193 (38%), Positives = 107/193 (55%), Gaps = 6/193 (3%)
Frame = +2
Query: 110 YFEEFVHRFNKNYSSEVEKLRRFKIFQHNLNEI-INKNQNDSAKYEINKFSDLSKDETIA 286
+F+ + + K YS+E E R + F N +I + N N + K +N+FSD+S E
Sbjct: 34 HFKSWTSKHRKTYSTE-EYHHRLQTFASNWRKINAHNNGNHTFKMALNQFSDMSFAEIKH 92
Query: 287 KYTGLSLPTQTQNFCKVILLDQPPGKGPL--EFDWRRL-NKVTSVKNQGMCGACWAFATL 457
KY L ++ QN C + G GP DWR+ N V+ VKNQG CG+CW F+T
Sbjct: 93 KY----LWSEPQN-CSATKSNYLRGTGPYPPSVDWRKKGNFVSPVKNQGACGSCWTFSTT 147
Query: 458 GSLESQFAIKHNELINLSEQQMIDC--DFVDAGCNGGLLHTAFEAIIKMGGVQLESDYPY 631
G+LES AI ++++L+EQQ++DC DF + GC GGL AFE I+ G+ E YPY
Sbjct: 148 GALESAIAIATGKMLSLAEQQLVDCAQDFNNHGCQGGLPSQAFEYILYNKGIMGEDTYPY 207
Query: 632 EADNNNCRMNSNK 670
+ + C+ K
Sbjct: 208 QGKDGYCKFQPGK 220
>CR541676-1|CAG46477.1| 331|Homo sapiens CTSS protein.
Length = 331
Score = 120 bits (288), Expect = 6e-27
Identities = 66/219 (30%), Positives = 115/219 (52%), Gaps = 8/219 (3%)
Frame = +2
Query: 32 MNKILFYLFVYAVVKSAAYDPLKAPNYFEEFVHRFNKNYSSEVEKLRRFKIFQHNLNEII 211
M +++ L V + + + +++ + + K Y + E+ R I++ NL ++
Sbjct: 1 MKRLVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVM 60
Query: 212 NKNQNDSA---KYEI--NKFSDLSKDETIAKYTGLSLPTQTQNFCKVILLDQPPGKGPLE 376
N S Y++ N D++ +E ++ + L +P+Q Q + P P
Sbjct: 61 LHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLRVPSQWQR--NITYKSNPNWILPDS 118
Query: 377 FDWRRLNKVTSVKNQGMCGACWAFATLGSLESQFAIKHNELINLSEQQMIDCD---FVDA 547
DWR VT VK QG CGACWAF+ +G+LE+Q +K +L++LS Q ++DC + +
Sbjct: 119 VDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNK 178
Query: 548 GCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMNS 664
GCNGG + TAF+ II G+ ++ YPY+A + C+ +S
Sbjct: 179 GCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDS 217
>BC002642-1|AAH02642.1| 331|Homo sapiens cathepsin S protein.
Length = 331
Score = 120 bits (288), Expect = 6e-27
Identities = 66/219 (30%), Positives = 115/219 (52%), Gaps = 8/219 (3%)
Frame = +2
Query: 32 MNKILFYLFVYAVVKSAAYDPLKAPNYFEEFVHRFNKNYSSEVEKLRRFKIFQHNLNEII 211
M +++ L V + + + +++ + + K Y + E+ R I++ NL ++
Sbjct: 1 MKRLVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVM 60
Query: 212 NKNQNDSA---KYEI--NKFSDLSKDETIAKYTGLSLPTQTQNFCKVILLDQPPGKGPLE 376
N S Y++ N D++ +E ++ + L +P+Q Q + P P
Sbjct: 61 LHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLRVPSQWQR--NITYKSNPNWILPDS 118
Query: 377 FDWRRLNKVTSVKNQGMCGACWAFATLGSLESQFAIKHNELINLSEQQMIDCD---FVDA 547
DWR VT VK QG CGACWAF+ +G+LE+Q +K +L++LS Q ++DC + +
Sbjct: 119 VDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNK 178
Query: 548 GCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMNS 664
GCNGG + TAF+ II G+ ++ YPY+A + C+ +S
Sbjct: 179 GCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDS 217
>AL356292-9|CAI13657.1| 331|Homo sapiens cathepsin S protein.
Length = 331
Score = 120 bits (288), Expect = 6e-27
Identities = 66/219 (30%), Positives = 115/219 (52%), Gaps = 8/219 (3%)
Frame = +2
Query: 32 MNKILFYLFVYAVVKSAAYDPLKAPNYFEEFVHRFNKNYSSEVEKLRRFKIFQHNLNEII 211
M +++ L V + + + +++ + + K Y + E+ R I++ NL ++
Sbjct: 1 MKRLVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVM 60
Query: 212 NKNQNDSA---KYEI--NKFSDLSKDETIAKYTGLSLPTQTQNFCKVILLDQPPGKGPLE 376
N S Y++ N D++ +E ++ + L +P+Q Q + P P
Sbjct: 61 LHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLRVPSQWQR--NITYKSNPNRILPDS 118
Query: 377 FDWRRLNKVTSVKNQGMCGACWAFATLGSLESQFAIKHNELINLSEQQMIDCD---FVDA 547
DWR VT VK QG CGACWAF+ +G+LE+Q +K +L++LS Q ++DC + +
Sbjct: 119 VDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNK 178
Query: 548 GCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMNS 664
GCNGG + TAF+ II G+ ++ YPY+A + C+ +S
Sbjct: 179 GCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDS 217
>U07374-1|AAB60643.2| 267|Homo sapiens cathepsin S protein.
Length = 267
Score = 119 bits (286), Expect = 1e-26
Identities = 66/219 (30%), Positives = 114/219 (52%), Gaps = 8/219 (3%)
Frame = +2
Query: 32 MNKILFYLFVYAVVKSAAYDPLKAPNYFEEFVHRFNKNYSSEVEKLRRFKIFQHNLNEII 211
M +++ L V + + + +++ + + K Y + E+ R I++ NL ++
Sbjct: 1 MKRLVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVM 60
Query: 212 NKNQNDSA---KYEI--NKFSDLSKDETIAKYTGLSLPTQTQNFCKVILLDQPPGKGPLE 376
N S Y++ N D++ +E ++ + L +P+Q Q + P P
Sbjct: 61 LHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLTSSLRVPSQWQR--NITYKSNPNRILPDS 118
Query: 377 FDWRRLNKVTSVKNQGMCGACWAFATLGSLESQFAIKHNELINLSEQQMIDCD---FVDA 547
DWR VT VK QG CGACWAF+ +G+LE+Q +K +L+ LS Q ++DC + +
Sbjct: 119 VDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVTLSAQNLVDCSTEKYGNK 178
Query: 548 GCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMNS 664
GCNGG + TAF+ II G+ ++ YPY+A + C+ +S
Sbjct: 179 GCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDS 217
>S93414-1|AAB22005.1| 331|Homo sapiens cathepsin S protein.
Length = 331
Score = 119 bits (286), Expect = 1e-26
Identities = 66/219 (30%), Positives = 114/219 (52%), Gaps = 8/219 (3%)
Frame = +2
Query: 32 MNKILFYLFVYAVVKSAAYDPLKAPNYFEEFVHRFNKNYSSEVEKLRRFKIFQHNLNEII 211
M +++ L V + + + +++ + + K Y + E+ R I++ NL ++
Sbjct: 1 MKRLVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVM 60
Query: 212 NKNQNDSA---KYEI--NKFSDLSKDETIAKYTGLSLPTQTQNFCKVILLDQPPGKGPLE 376
N S Y++ N D++ +E ++ + L +P+Q Q + P P
Sbjct: 61 LHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLTSSLRVPSQWQR--NITYKSNPNRILPDS 118
Query: 377 FDWRRLNKVTSVKNQGMCGACWAFATLGSLESQFAIKHNELINLSEQQMIDCD---FVDA 547
DWR VT VK QG CGACWAF+ +G+LE+Q +K +L+ LS Q ++DC + +
Sbjct: 119 VDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVTLSAQNLVDCSTEKYGNK 178
Query: 548 GCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMNS 664
GCNGG + TAF+ II G+ ++ YPY+A + C+ +S
Sbjct: 179 GCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDS 217
>M86553-1|AAA35655.1| 331|Homo sapiens cathepsin protein.
Length = 331
Score = 119 bits (286), Expect = 1e-26
Identities = 66/219 (30%), Positives = 114/219 (52%), Gaps = 8/219 (3%)
Frame = +2
Query: 32 MNKILFYLFVYAVVKSAAYDPLKAPNYFEEFVHRFNKNYSSEVEKLRRFKIFQHNLNEII 211
M +++ L V + + + +++ + + K Y + E+ R I++ NL ++
Sbjct: 1 MKRLVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVM 60
Query: 212 NKNQNDSA---KYEI--NKFSDLSKDETIAKYTGLSLPTQTQNFCKVILLDQPPGKGPLE 376
N S Y++ N D++ +E ++ + L +P+Q Q + P P
Sbjct: 61 LHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLTSSLRVPSQWQR--NITYKSNPNRILPDS 118
Query: 377 FDWRRLNKVTSVKNQGMCGACWAFATLGSLESQFAIKHNELINLSEQQMIDCD---FVDA 547
DWR VT VK QG CGACWAF+ +G+LE+Q +K +L+ LS Q ++DC + +
Sbjct: 119 VDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVTLSAQNLVDCSTEKYGNK 178
Query: 548 GCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMNS 664
GCNGG + TAF+ II G+ ++ YPY+A + C+ +S
Sbjct: 179 GCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDS 217
>M90696-1|AAC37592.1| 331|Homo sapiens cathepsin S protein.
Length = 331
Score = 118 bits (285), Expect = 1e-26
Identities = 66/219 (30%), Positives = 115/219 (52%), Gaps = 8/219 (3%)
Frame = +2
Query: 32 MNKILFYLFVYAVVKSAAYDPLKAPNYFEEFVHRFNKNYSSEVEKLRRFKIFQHNLNEII 211
M +++ L V + + + +++ + + K Y + E+ R I++ NL ++
Sbjct: 1 MKRLVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVM 60
Query: 212 NKNQNDSA---KYEI--NKFSDLSKDETIAKYTGLSLPTQTQNFCKVILLDQPPGKGPLE 376
N S Y++ N D++ +E ++ + L +P+Q Q + P P
Sbjct: 61 LHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLRVPSQWQR--NITYKSNPNRILPDS 118
Query: 377 FDWRRLNKVTSVKNQGMCGACWAFATLGSLESQFAIKHNELINLSEQQMIDCD---FVDA 547
DWR VT VK QG CGACWAF+ +G+LE+Q +K +L++LS Q ++DC + +
Sbjct: 119 VDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNK 178
Query: 548 GCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMNS 664
GCNGG + TAF+ II G+ ++ YPY+A + C+ +S
Sbjct: 179 GCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDLKCQYDS 217
>AL355860-2|CAI12796.1| 258|Homo sapiens cathepsin K protein.
Length = 258
Score = 117 bits (282), Expect = 3e-26
Identities = 63/188 (33%), Positives = 100/188 (53%), Gaps = 5/188 (2%)
Frame = +2
Query: 68 VVKSAAYDPLKAPNYFEEFVHRFNKNYSSEVEKLRRFKIFQHNLNEIINKNQNDSA---K 238
VV A Y ++E + K Y+++V+++ R I++ NL I N S
Sbjct: 70 VVSFALYPEEILDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHT 129
Query: 239 YEI--NKFSDLSKDETIAKYTGLSLPTQTQNFCKVILLDQPPGKGPLEFDWRRLNKVTSV 412
YE+ N D++ +E + K TGL +P + + + G+ P D+R+ VT V
Sbjct: 130 YELAMNHLGDMTSEEVVQKMTGLKVPLSHSRSNDTLYIPEWEGRAPDSVDYRKKGYVTPV 189
Query: 413 KNQGMCGACWAFATLGSLESQFAIKHNELINLSEQQMIDCDFVDAGCNGGLLHTAFEAII 592
KNQG CG+CWAF+++G+LE Q K +L+NLS Q ++DC + GC GG + AF+ +
Sbjct: 190 KNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGGYMTNAFQYVQ 249
Query: 593 KMGGVQLE 616
K G+ E
Sbjct: 250 KNRGIDSE 257
>X77383-1|CAA54562.1| 321|Homo sapiens cathepsin O protein.
Length = 321
Score = 114 bits (274), Expect = 3e-25
Identities = 64/162 (39%), Positives = 93/162 (57%), Gaps = 2/162 (1%)
Frame = +2
Query: 173 RFKIFQHNLNEIINKNQNDSAKYEINKFSDLSKDETIAKYTGLSLPTQTQNFCKVILLDQ 352
R + +H + ++N +A Y IN+FS L +E A Y S P++ + + +
Sbjct: 45 RESLNRHRYLNSLFPSENSTAFYGINQFSYLFPEEFKAIYLR-SKPSKFPRYSAEVHMSI 103
Query: 353 PPGKGPLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQFAIKHNELINLSEQQMIDC 532
P PL FDWR VT V+NQ MCG CWAF+ +G++ES +AIK L +LS QQ+IDC
Sbjct: 104 PNVSLPLRFDWRDKQVVTQVRNQQMCGGCWAFSVVGAVESAYAIKGKPLEDLSVQQVIDC 163
Query: 533 DFVDAGCNGGLLHTAFEAIIKMGGVQL--ESDYPYEADNNNC 652
+ + GCNGG A + KM V+L +S+YP++A N C
Sbjct: 164 SYNNYGCNGGSTLNALNWLNKM-QVKLVKDSEYPFKAQNGLC 204
>BC049206-1|AAH49206.1| 321|Homo sapiens cathepsin O protein.
Length = 321
Score = 114 bits (274), Expect = 3e-25
Identities = 64/162 (39%), Positives = 93/162 (57%), Gaps = 2/162 (1%)
Frame = +2
Query: 173 RFKIFQHNLNEIINKNQNDSAKYEINKFSDLSKDETIAKYTGLSLPTQTQNFCKVILLDQ 352
R + +H + ++N +A Y IN+FS L +E A Y S P++ + + +
Sbjct: 45 RESLNRHRYLNSLFPSENSTAFYGINQFSYLFPEEFKAIYLR-SKPSKFPRYSAEVHMSI 103
Query: 353 PPGKGPLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQFAIKHNELINLSEQQMIDC 532
P PL FDWR VT V+NQ MCG CWAF+ +G++ES +AIK L +LS QQ+IDC
Sbjct: 104 PNVSLPLRFDWRDKQVVTQVRNQQMCGGCWAFSVVGAVESAYAIKGKPLEDLSVQQVIDC 163
Query: 533 DFVDAGCNGGLLHTAFEAIIKMGGVQL--ESDYPYEADNNNC 652
+ + GCNGG A + KM V+L +S+YP++A N C
Sbjct: 164 SYNNYGCNGGSTLNALNWLNKM-QVKLVKDSEYPFKAQNGLC 204
>X12451-1|CAA30981.1| 333|Homo sapiens pro-(cathepsin L) protein.
Length = 333
Score = 109 bits (261), Expect = 1e-23
Identities = 66/183 (36%), Positives = 92/183 (50%), Gaps = 8/183 (4%)
Frame = +2
Query: 137 NKNYSSEVEKLRRFKIFQHNLNEIINKNQN-----DSAKYEINKFSDLSKDETIAKYTGL 301
N+ Y E RR +++ N+ I NQ S +N F D++ +E G
Sbjct: 37 NRLYGMNEEGWRR-AVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGF 95
Query: 302 SLPTQTQNFCKVILLDQPPG-KGPLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQF 478
Q + K + +P + P DWR VT VKNQG CG+CWAF+ G+LE Q
Sbjct: 96 ----QNRKPRKGKVFQEPLFYEAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQM 151
Query: 479 AIKHNELINLSEQQMIDCDFV--DAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNC 652
K LI+LSEQ ++DC + GCNGGL+ AF+ + GG+ E YPYEA +C
Sbjct: 152 FRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESC 211
Query: 653 RMN 661
+ N
Sbjct: 212 KYN 214
>M20496-1|AAA66974.1| 333|Homo sapiens CTSL protein.
Length = 333
Score = 109 bits (261), Expect = 1e-23
Identities = 66/183 (36%), Positives = 92/183 (50%), Gaps = 8/183 (4%)
Frame = +2
Query: 137 NKNYSSEVEKLRRFKIFQHNLNEIINKNQN-----DSAKYEINKFSDLSKDETIAKYTGL 301
N+ Y E RR +++ N+ I NQ S +N F D++ +E G
Sbjct: 37 NRLYGMNEEGWRR-AVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGF 95
Query: 302 SLPTQTQNFCKVILLDQPPG-KGPLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQF 478
Q + K + +P + P DWR VT VKNQG CG+CWAF+ G+LE Q
Sbjct: 96 ----QNRKPRKGKVFQEPLFYEAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQM 151
Query: 479 AIKHNELINLSEQQMIDCDFV--DAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNC 652
K LI+LSEQ ++DC + GCNGGL+ AF+ + GG+ E YPYEA +C
Sbjct: 152 FRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESC 211
Query: 653 RMN 661
+ N
Sbjct: 212 KYN 214
>CR457053-1|CAG33334.1| 333|Homo sapiens CTSL protein.
Length = 333
Score = 109 bits (261), Expect = 1e-23
Identities = 66/183 (36%), Positives = 92/183 (50%), Gaps = 8/183 (4%)
Frame = +2
Query: 137 NKNYSSEVEKLRRFKIFQHNLNEIINKNQN-----DSAKYEINKFSDLSKDETIAKYTGL 301
N+ Y E RR +++ N+ I NQ S +N F D++ +E G
Sbjct: 37 NRLYGMNEEGWRR-AVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGF 95
Query: 302 SLPTQTQNFCKVILLDQPPG-KGPLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQF 478
Q + K + +P + P DWR VT VKNQG CG+CWAF+ G+LE Q
Sbjct: 96 ----QNRKPRKGKVFQEPLFYEAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQM 151
Query: 479 AIKHNELINLSEQQMIDCDFV--DAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNC 652
K LI+LSEQ ++DC + GCNGGL+ AF+ + GG+ E YPYEA +C
Sbjct: 152 FRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESC 211
Query: 653 RMN 661
+ N
Sbjct: 212 KYN 214
>BC048255-1|AAH48255.1| 376|Homo sapiens cathepsin W protein.
Length = 376
Score = 109 bits (261), Expect = 1e-23
Identities = 56/197 (28%), Positives = 100/197 (50%), Gaps = 3/197 (1%)
Frame = +2
Query: 92 PLKAPNYFEEFVHRFNKNYSSEVEKLRRFKIFQHNLNEIINKNQND--SAKYEINKFSDL 265
PL+ F+ F +FN++Y S E R IF HNL + + D +A++ + FSDL
Sbjct: 35 PLELKEAFKLFQIQFNRSYLSPEEHAHRLDIFAHNLAQAQRLQEEDLGTAEFGVTPFSDL 94
Query: 266 SKDETIAKYTGLSLPTQTQNFCKVILLDQPPGKGPLEFDWRRL-NKVTSVKNQGMCGACW 442
+++E Y + + I ++P P DWR++ ++ +K+Q C CW
Sbjct: 95 TEEEFGQLYGYRRAAGGVPSMGREIRSEEPEESVPFSCDWRKVAGAISPIKDQKNCNCCW 154
Query: 443 AFATLGSLESQFAIKHNELINLSEQQMIDCDFVDAGCNGGLLHTAFEAIIKMGGVQLESD 622
A A G++E+ + I + +++S Q+++DC GC+GG + AF ++ G+ E D
Sbjct: 155 AMAAAGNIETLWRISFWDFVDVSVQELLDCGRCGDGCHGGFVWDAFITVLNNSGLASEKD 214
Query: 623 YPYEADNNNCRMNSNKF 673
YP++ R + K+
Sbjct: 215 YPFQGKVRAHRCHPKKY 231
>AL160279-3|CAI16308.1| 333|Homo sapiens cathepsin L1 protein.
Length = 333
Score = 109 bits (261), Expect = 1e-23
Identities = 66/183 (36%), Positives = 92/183 (50%), Gaps = 8/183 (4%)
Frame = +2
Query: 137 NKNYSSEVEKLRRFKIFQHNLNEIINKNQN-----DSAKYEINKFSDLSKDETIAKYTGL 301
N+ Y E RR +++ N+ I NQ S +N F D++ +E G
Sbjct: 37 NRLYGMNEEGWRR-AVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGF 95
Query: 302 SLPTQTQNFCKVILLDQPPG-KGPLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQF 478
Q + K + +P + P DWR VT VKNQG CG+CWAF+ G+LE Q
Sbjct: 96 ----QNRKPRKGKVFQEPLFYEAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQM 151
Query: 479 AIKHNELINLSEQQMIDCDFV--DAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNC 652
K LI+LSEQ ++DC + GCNGGL+ AF+ + GG+ E YPYEA +C
Sbjct: 152 FRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESC 211
Query: 653 RMN 661
+ N
Sbjct: 212 KYN 214
>BC012612-1|AAH12612.1| 333|Homo sapiens cathepsin L1 protein.
Length = 333
Score = 108 bits (260), Expect = 2e-23
Identities = 66/183 (36%), Positives = 92/183 (50%), Gaps = 8/183 (4%)
Frame = +2
Query: 137 NKNYSSEVEKLRRFKIFQHNLNEIINKNQN-----DSAKYEINKFSDLSKDETIAKYTGL 301
N+ Y E RR +++ N+ I NQ S +N F D++ +E G
Sbjct: 37 NRLYGMNEEGWRR-AVWEKNVKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGF 95
Query: 302 SLPTQTQNFCKVILLDQPPG-KGPLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQF 478
Q + K + +P + P DWR VT VKNQG CG+CWAF+ G+LE Q
Sbjct: 96 ----QNRKPRKGKVFQEPLFYEAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQM 151
Query: 479 AIKHNELINLSEQQMIDCDFV--DAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNC 652
K LI+LSEQ ++DC + GCNGGL+ AF+ + GG+ E YPYEA +C
Sbjct: 152 FRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESC 211
Query: 653 RMN 661
+ N
Sbjct: 212 KYN 214
>BC142983-1|AAI42984.1| 333|Homo sapiens cathepsin L1 protein.
Length = 333
Score = 108 bits (259), Expect = 2e-23
Identities = 66/183 (36%), Positives = 92/183 (50%), Gaps = 8/183 (4%)
Frame = +2
Query: 137 NKNYSSEVEKLRRFKIFQHNLNEIINKNQN-----DSAKYEINKFSDLSKDETIAKYTGL 301
N+ Y E RR +++ N+ I NQ S +N F D++ +E G
Sbjct: 37 NRLYGMNEEGWRR-AVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGF 95
Query: 302 SLPTQTQNFCKVILLDQPPG-KGPLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQF 478
Q + K + +P + P DWR VT VKNQG CG+CWAF+ G+LE Q
Sbjct: 96 ----QNRKPRKGKVFQEPLFYEAPRSVDWREKGYVTPVKNQGPCGSCWAFSATGALEGQM 151
Query: 479 AIKHNELINLSEQQMIDCDFV--DAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNC 652
K LI+LSEQ ++DC + GCNGGL+ AF+ + GG+ E YPYEA +C
Sbjct: 152 FRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESC 211
Query: 653 RMN 661
+ N
Sbjct: 212 KYN 214
>AF055903-1|AAC32181.1| 376|Homo sapiens cathepsin W protein.
Length = 376
Score = 107 bits (256), Expect = 5e-23
Identities = 55/197 (27%), Positives = 99/197 (50%), Gaps = 3/197 (1%)
Frame = +2
Query: 92 PLKAPNYFEEFVHRFNKNYSSEVEKLRRFKIFQHNLNEIINKNQND--SAKYEINKFSDL 265
PL+ F+ F +FN++Y S E R IF HNL + + D +A++ + FSDL
Sbjct: 35 PLELKEAFKLFQIQFNRSYLSPEEHAHRLDIFAHNLAQAQRLQEEDLGTAEFGVTPFSDL 94
Query: 266 SKDETIAKYTGLSLPTQTQNFCKVILLDQPPGKGPLEFDWRRL-NKVTSVKNQGMCGACW 442
+++E Y + + I ++P P DWR++ ++ +K+Q C CW
Sbjct: 95 TEEEFGQLYGYRRAAGGVPSMGREIRSEEPEESVPFSCDWRKVAGAISPIKDQKNCNCCW 154
Query: 443 AFATLGSLESQFAIKHNELINLSEQQMIDCDFVDAGCNGGLLHTAFEAIIKMGGVQLESD 622
A A G++E+ + I + +++S +++DC GC+GG + AF ++ G+ E D
Sbjct: 155 AMAAAGNIETLWRISFWDFVDVSVHELLDCGRCGDGCHGGFVWDAFITVLNNSGLASEKD 214
Query: 623 YPYEADNNNCRMNSNKF 673
YP++ R + K+
Sbjct: 215 YPFQGKVRAHRCHPKKY 231
>AF015954-1|AAB82457.1| 376|Homo sapiens lymphopain protein.
Length = 376
Score = 107 bits (256), Expect = 5e-23
Identities = 55/197 (27%), Positives = 99/197 (50%), Gaps = 3/197 (1%)
Frame = +2
Query: 92 PLKAPNYFEEFVHRFNKNYSSEVEKLRRFKIFQHNLNEIINKNQND--SAKYEINKFSDL 265
PL+ F+ F +FN++Y S E R IF HNL + + D +A++ + FSDL
Sbjct: 35 PLELKEAFKLFQIQFNRSYLSPEEHAHRLDIFAHNLAQAQRLQEEDLGTAEFGVTPFSDL 94
Query: 266 SKDETIAKYTGLSLPTQTQNFCKVILLDQPPGKGPLEFDWRRL-NKVTSVKNQGMCGACW 442
+++E Y + + I ++P P DWR++ ++ +K+Q C CW
Sbjct: 95 TEEEFGQLYGYRRAAGGVPSMGREIRSEEPEESVPFSCDWRKVAGAISPIKDQKNCNCCW 154
Query: 443 AFATLGSLESQFAIKHNELINLSEQQMIDCDFVDAGCNGGLLHTAFEAIIKMGGVQLESD 622
A A G++E+ + I + +++S +++DC GC+GG + AF ++ G+ E D
Sbjct: 155 AMAAAGNIETLWRISFWDFVDVSVHELLDCGRCGDGCHGGFVWDAFITVLNNSGLASEKD 214
Query: 623 YPYEADNNNCRMNSNKF 673
YP++ R + K+
Sbjct: 215 YPFQGKVRAHRCHPKKY 231
>AF013611-1|AAB82449.1| 376|Homo sapiens lymphopain protein.
Length = 376
Score = 107 bits (256), Expect = 5e-23
Identities = 55/197 (27%), Positives = 99/197 (50%), Gaps = 3/197 (1%)
Frame = +2
Query: 92 PLKAPNYFEEFVHRFNKNYSSEVEKLRRFKIFQHNLNEIINKNQND--SAKYEINKFSDL 265
PL+ F+ F +FN++Y S E R IF HNL + + D +A++ + FSDL
Sbjct: 35 PLELKEAFKLFQIQFNRSYLSPEEHAHRLDIFAHNLAQAQRLQEEDLGTAEFGVTPFSDL 94
Query: 266 SKDETIAKYTGLSLPTQTQNFCKVILLDQPPGKGPLEFDWRRL-NKVTSVKNQGMCGACW 442
+++E Y + + I ++P P DWR++ ++ +K+Q C CW
Sbjct: 95 TEEEFGQLYGYRRAAGGVPSMGREIRSEEPEESVPFSCDWRKVAGAISPIKDQKNCNCCW 154
Query: 443 AFATLGSLESQFAIKHNELINLSEQQMIDCDFVDAGCNGGLLHTAFEAIIKMGGVQLESD 622
A A G++E+ + I + +++S +++DC GC+GG + AF ++ G+ E D
Sbjct: 155 AMAAAGNIETLWRISFWDFVDVSVHELLDCGRCGDGCHGGFVWDAFITVLNNSGLASEKD 214
Query: 623 YPYEADNNNCRMNSNKF 673
YP++ R + K+
Sbjct: 215 YPFQGKVRAHRCHPKKY 231
>AL160279-2|CAI16307.1| 225|Homo sapiens cathepsin L1 protein.
Length = 225
Score = 103 bits (247), Expect = 6e-22
Identities = 67/189 (35%), Positives = 94/189 (49%), Gaps = 10/189 (5%)
Frame = +2
Query: 137 NKNYSSEVEKLRRFKIFQHNLNEIINKNQN-----DSAKYEINKFSDLSKDETIAKYTGL 301
N+ Y E RR +++ N+ I NQ S +N F D++ +E G
Sbjct: 37 NRLYGMNEEGWRR-AVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGF 95
Query: 302 SLPTQTQNFCKVILLDQPPG-KGPLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQF 478
Q + K + +P + P DWR VT VKNQG CG+CWAF+ G+LE Q
Sbjct: 96 ----QNRKPRKGKVFQEPLFYEAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQM 151
Query: 479 AIKHNELINLSEQQMIDCDFV--DAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNN- 649
K LI+LSEQ ++DC + GCNGGL+ AF+ + GG+ E YPYEA +
Sbjct: 152 FRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATVSGA 211
Query: 650 -CRMNSNKF 673
C +S+ F
Sbjct: 212 PCHHSSSAF 220
>X07549-1|CAA30428.1| 248|Homo sapiens cathepsin H protein.
Length = 248
Score = 102 bits (244), Expect = 1e-21
Identities = 48/107 (44%), Positives = 66/107 (61%), Gaps = 3/107 (2%)
Frame = +2
Query: 359 GKGPLEFDWRRL-NKVTSVKNQGMCGACWAFATLGSLESQFAIKHNELINLSEQQMIDC- 532
G P DWR+ N V+ VKNQG CG+CW F+T G+LES AI ++++L+EQQ++DC
Sbjct: 27 GPYPPSVDWRKKGNFVSPVKNQGACGSCWTFSTTGALESAIAIATGKMLSLAEQQLVDCA 86
Query: 533 -DFVDAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMNSNK 670
DF + GC GGL AFE I+ G+ E YPY+ + C+ K
Sbjct: 87 QDFNNYGCQGGLPSQAFEYILYNKGIMGEDTYPYQGKDGYCKFQPGK 133
>Y14734-1|CAA75029.1| 334|Homo sapiens cathepsin L2 protein.
Length = 334
Score = 98.3 bits (234), Expect = 2e-20
Identities = 56/174 (32%), Positives = 89/174 (51%), Gaps = 4/174 (2%)
Frame = +2
Query: 146 YSSEVEKLRRFKIFQHNLNEI-INKNQNDSAKYEINKFSDLSKDETIAKYTGLSLPTQTQ 322
Y + E RR +++ N+ I ++ + K+ + D T ++ + + Q
Sbjct: 40 YGANEEGWRR-AVWEKNMKMIELHNGEYSQGKHGFTMAMNAFPDMTNEEFRQMMGCFRNQ 98
Query: 323 NFCKVILLDQPPGKG-PLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQFAIKHNEL 499
F K + +P P DWR+ VT VKNQ CG+CWAF+ G+LE Q K +L
Sbjct: 99 KFRKGKVFREPLFLDLPKSVDWRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKL 158
Query: 500 INLSEQQMIDCDFV--DAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCR 655
++LSEQ ++DC + GCNGG + AF+ + + GG+ E YPY A + C+
Sbjct: 159 VSLSEQNLVDCSRPQGNQGCNGGFMARAFQYVKENGGLDSEESYPYVAVDEICK 212
>Y18462-1|CAA77180.1| 175|Homo sapiens cathepsin L protein.
Length = 175
Score = 97.9 bits (233), Expect = 3e-20
Identities = 44/89 (49%), Positives = 57/89 (64%), Gaps = 2/89 (2%)
Frame = +2
Query: 401 VTSVKNQGMCGACWAFATLGSLESQFAIKHNELINLSEQQMIDCDFV--DAGCNGGLLHT 574
VT VKNQG CG+CWAF+ G+LE Q K LI+LSEQ ++DC + GCNGGL+
Sbjct: 1 VTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDY 60
Query: 575 AFEAIIKMGGVQLESDYPYEADNNNCRMN 661
AF+ + GG+ E YPYEA +C+ N
Sbjct: 61 AFQYVQDNGGLDSEESYPYEATEESCKYN 89
>BC110512-1|AAI10513.1| 334|Homo sapiens cathepsin L2 protein.
Length = 334
Score = 97.9 bits (233), Expect = 3e-20
Identities = 56/174 (32%), Positives = 89/174 (51%), Gaps = 4/174 (2%)
Frame = +2
Query: 146 YSSEVEKLRRFKIFQHNLNEI-INKNQNDSAKYEINKFSDLSKDETIAKYTGLSLPTQTQ 322
Y + E RR +++ N+ I ++ + K+ + D T ++ + + Q
Sbjct: 40 YGANEEGWRR-AVWEKNMKMIELHNGEYSQGKHGFTMAMNAFGDMTNEEFRQMMGCFRNQ 98
Query: 323 NFCKVILLDQPPGKG-PLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQFAIKHNEL 499
F K + +P P DWR+ VT VKNQ CG+CWAF+ G+LE Q K +L
Sbjct: 99 KFRKGKVFREPLFLDLPKSVDWRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKL 158
Query: 500 INLSEQQMIDCDFV--DAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCR 655
++LSEQ ++DC + GCNGG + AF+ + + GG+ E YPY A + C+
Sbjct: 159 VSLSEQNLVDCSRPQGNQGCNGGFMARAFQYVKENGGLDSEESYPYVAVDEICK 212
>BC023504-1|AAH23504.1| 334|Homo sapiens CTSL2 protein protein.
Length = 334
Score = 97.9 bits (233), Expect = 3e-20
Identities = 56/174 (32%), Positives = 89/174 (51%), Gaps = 4/174 (2%)
Frame = +2
Query: 146 YSSEVEKLRRFKIFQHNLNEI-INKNQNDSAKYEINKFSDLSKDETIAKYTGLSLPTQTQ 322
Y + E RR +++ N+ I ++ + K+ + D T ++ + + Q
Sbjct: 40 YGANEEGWRR-AVWEKNMKMIELHNGEYSQGKHGFTMAMNAFGDMTNEEFRQMMGCFRNQ 98
Query: 323 NFCKVILLDQPPGKG-PLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQFAIKHNEL 499
F K + +P P DWR+ VT VKNQ CG+CWAF+ G+LE Q K +L
Sbjct: 99 KFRKGKVFREPLFLDLPKSVDWRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKL 158
Query: 500 INLSEQQMIDCDFV--DAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCR 655
++LSEQ ++DC + GCNGG + AF+ + + GG+ E YPY A + C+
Sbjct: 159 VSLSEQNLVDCSRPQGNQGCNGGFMARAFQYVKENGGLDSEESYPYVAVDEICK 212
>AY358641-1|AAQ89004.1| 334|Homo sapiens cathepsin L2 protein.
Length = 334
Score = 97.9 bits (233), Expect = 3e-20
Identities = 56/174 (32%), Positives = 89/174 (51%), Gaps = 4/174 (2%)
Frame = +2
Query: 146 YSSEVEKLRRFKIFQHNLNEI-INKNQNDSAKYEINKFSDLSKDETIAKYTGLSLPTQTQ 322
Y + E RR +++ N+ I ++ + K+ + D T ++ + + Q
Sbjct: 40 YGANEEGWRR-AVWEKNMKMIELHNGEYSQGKHGFTMAMNAFGDMTNEEFRQMMGCFRNQ 98
Query: 323 NFCKVILLDQPPGKG-PLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQFAIKHNEL 499
F K + +P P DWR+ VT VKNQ CG+CWAF+ G+LE Q K +L
Sbjct: 99 KFRKGKVFREPLFLDLPKSVDWRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKL 158
Query: 500 INLSEQQMIDCDFV--DAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCR 655
++LSEQ ++DC + GCNGG + AF+ + + GG+ E YPY A + C+
Sbjct: 159 VSLSEQNLVDCSRPQGNQGCNGGFMARAFQYVKENGGLDSEESYPYVAVDEICK 212
>AL445670-2|CAI15053.1| 334|Homo sapiens cathepsin L2 protein.
Length = 334
Score = 97.9 bits (233), Expect = 3e-20
Identities = 56/174 (32%), Positives = 89/174 (51%), Gaps = 4/174 (2%)
Frame = +2
Query: 146 YSSEVEKLRRFKIFQHNLNEI-INKNQNDSAKYEINKFSDLSKDETIAKYTGLSLPTQTQ 322
Y + E RR +++ N+ I ++ + K+ + D T ++ + + Q
Sbjct: 40 YGANEEGWRR-AVWEKNMKMIELHNGEYSQGKHGFTMAMNAFGDMTNEEFRQMMGCFRNQ 98
Query: 323 NFCKVILLDQPPGKG-PLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQFAIKHNEL 499
F K + +P P DWR+ VT VKNQ CG+CWAF+ G+LE Q K +L
Sbjct: 99 KFRKGKVFREPLFLDLPKSVDWRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKL 158
Query: 500 INLSEQQMIDCDFV--DAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCR 655
++LSEQ ++DC + GCNGG + AF+ + + GG+ E YPY A + C+
Sbjct: 159 VSLSEQNLVDCSRPQGNQGCNGGFMARAFQYVKENGGLDSEESYPYVAVDEICK 212
>AF070448-1|AAC23598.1| 334|Homo sapiens cathepsin U protein.
Length = 334
Score = 97.9 bits (233), Expect = 3e-20
Identities = 56/174 (32%), Positives = 89/174 (51%), Gaps = 4/174 (2%)
Frame = +2
Query: 146 YSSEVEKLRRFKIFQHNLNEI-INKNQNDSAKYEINKFSDLSKDETIAKYTGLSLPTQTQ 322
Y + E RR +++ N+ I ++ + K+ + D T ++ + + Q
Sbjct: 40 YGANEEGWRR-AVWEKNMKMIELHNGEYSQGKHGFTMAMNAFGDMTNEEFRQMMGCFRNQ 98
Query: 323 NFCKVILLDQPPGKG-PLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQFAIKHNEL 499
F K + +P P DWR+ VT VKNQ CG+CWAF+ G+LE Q K +L
Sbjct: 99 KFRKGKVFREPLFLDLPKSVDWRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKL 158
Query: 500 INLSEQQMIDCDFV--DAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCR 655
++LSEQ ++DC + GCNGG + AF+ + + GG+ E YPY A + C+
Sbjct: 159 VSLSEQNLVDCSRPQGNQGCNGGFMARAFQYVKENGGLDSEESYPYVAVDEICK 212
>AB019534-1|BAA34365.1| 334|Homo sapiens cathepsin L2 protein.
Length = 334
Score = 97.9 bits (233), Expect = 3e-20
Identities = 56/174 (32%), Positives = 89/174 (51%), Gaps = 4/174 (2%)
Frame = +2
Query: 146 YSSEVEKLRRFKIFQHNLNEI-INKNQNDSAKYEINKFSDLSKDETIAKYTGLSLPTQTQ 322
Y + E RR +++ N+ I ++ + K+ + D T ++ + + Q
Sbjct: 40 YGANEEGWRR-AVWEKNMKMIELHNGEYSQGKHGFTMAMNAFGDMTNEEFRQMMGCFRNQ 98
Query: 323 NFCKVILLDQPPGKG-PLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQFAIKHNEL 499
F K + +P P DWR+ VT VKNQ CG+CWAF+ G+LE Q K +L
Sbjct: 99 KFRKGKVFREPLFLDLPKSVDWRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKL 158
Query: 500 INLSEQQMIDCDFV--DAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCR 655
++LSEQ ++DC + GCNGG + AF+ + + GG+ E YPY A + C+
Sbjct: 159 VSLSEQNLVDCSRPQGNQGCNGGFMARAFQYVKENGGLDSEESYPYVAVDEICK 212
>AB001928-1|BAA25909.1| 334|Homo sapiens cathepsin V protein.
Length = 334
Score = 97.9 bits (233), Expect = 3e-20
Identities = 56/174 (32%), Positives = 89/174 (51%), Gaps = 4/174 (2%)
Frame = +2
Query: 146 YSSEVEKLRRFKIFQHNLNEI-INKNQNDSAKYEINKFSDLSKDETIAKYTGLSLPTQTQ 322
Y + E RR +++ N+ I ++ + K+ + D T ++ + + Q
Sbjct: 40 YGANEEGWRR-AVWEKNMKMIELHNGEYSQGKHGFTMAMNAFGDMTNEEFRQMMGCFRNQ 98
Query: 323 NFCKVILLDQPPGKG-PLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQFAIKHNEL 499
F K + +P P DWR+ VT VKNQ CG+CWAF+ G+LE Q K +L
Sbjct: 99 KFRKGKVFREPLFLDLPKSVDWRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKL 158
Query: 500 INLSEQQMIDCDFV--DAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCR 655
++LSEQ ++DC + GCNGG + AF+ + + GG+ E YPY A + C+
Sbjct: 159 VSLSEQNLVDCSRPQGNQGCNGGFMARAFQYVKENGGLDSEESYPYVAVDEICK 212
>Y18461-1|CAA77179.1| 166|Homo sapiens cathepsin H protein.
Length = 166
Score = 83.0 bits (196), Expect = 9e-16
Identities = 36/83 (43%), Positives = 52/83 (62%), Gaps = 2/83 (2%)
Frame = +2
Query: 428 CGACWAFATLGSLESQFAIKHNELINLSEQQMIDC--DFVDAGCNGGLLHTAFEAIIKMG 601
CG+CW F+T G+LES AI ++++L+EQQ++DC DF + GC GGL AFE I+
Sbjct: 1 CGSCWTFSTTGALESAIAIATGKMLSLAEQQLVDCAQDFNNHGCQGGLPSQAFEYILYNK 60
Query: 602 GVQLESDYPYEADNNNCRMNSNK 670
G+ E YPY+ + C+ K
Sbjct: 61 GIMGEDTYPYQGKDGYCKFQPGK 83
>X87212-1|CAA60671.1| 463|Homo sapiens cathepsin C protein.
Length = 463
Score = 67.7 bits (158), Expect = 4e-11
Identities = 48/190 (25%), Positives = 87/190 (45%), Gaps = 6/190 (3%)
Frame = +2
Query: 122 FVHRFNKNYSSEVEKLRRFKIFQHNLNEIINKNQNDSAKYEINKFSDLSKDETIAKYTGL 301
+V+ + S E R +K + HN + IN Q ++ L+ + I + G
Sbjct: 150 YVNTAHLKNSQEKYSNRLYK-YDHNFVKAINAIQKSWTATTYMEYETLTLGDMIRRSGGH 208
Query: 302 SLPTQTQNFCKVIL-LDQPPGKGPLEFDWRR---LNKVTSVKNQGMCGACWAFATLGSLE 469
S + + Q P +DWR +N V+ V+NQ CG+C++FA++G LE
Sbjct: 209 SRKIPRPKPAPLTAEIQQKILHLPTSWDWRNVHGINFVSPVRNQASCGSCYSFASMGMLE 268
Query: 470 SQFAI--KHNELINLSEQQMIDCDFVDAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADN 643
++ I +++ LS Q+++ C GC GG + + G+ E+ +PY +
Sbjct: 269 ARIRILTNNSQTPILSPQEVVSCSQYAQGCEGGFPYLIAGKYAQDFGLVEEACFPYTGTD 328
Query: 644 NNCRMNSNKF 673
+ C+M + F
Sbjct: 329 SPCKMKEDCF 338
>U79415-1|AAC51341.1| 463|Homo sapiens prepro dipeptidyl peptidase
I protein.
Length = 463
Score = 67.7 bits (158), Expect = 4e-11
Identities = 48/190 (25%), Positives = 87/190 (45%), Gaps = 6/190 (3%)
Frame = +2
Query: 122 FVHRFNKNYSSEVEKLRRFKIFQHNLNEIINKNQNDSAKYEINKFSDLSKDETIAKYTGL 301
+V+ + S E R +K + HN + IN Q ++ L+ + I + G
Sbjct: 150 YVNTAHLKNSQEKYSNRLYK-YDHNFVKAINAIQKSWTATTYMEYETLTLGDMIRRSGGH 208
Query: 302 SLPTQTQNFCKVIL-LDQPPGKGPLEFDWRR---LNKVTSVKNQGMCGACWAFATLGSLE 469
S + + Q P +DWR +N V+ V+NQ CG+C++FA++G LE
Sbjct: 209 SRKIPRPKPAPLTAEIQQKILHLPTSWDWRNVHGINFVSPVRNQASCGSCYSFASMGMLE 268
Query: 470 SQFAI--KHNELINLSEQQMIDCDFVDAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADN 643
++ I +++ LS Q+++ C GC GG + + G+ E+ +PY +
Sbjct: 269 ARIRILTNNSQTPILSPQEVVSCSQYAQGCEGGFPYLIAGKYAQDFGLVEEACFPYTGTD 328
Query: 644 NNCRMNSNKF 673
+ C+M + F
Sbjct: 329 SPCKMKEDCF 338
>AK223038-1|BAD96758.1| 463|Homo sapiens cathepsin C isoform a
preproprotein variant protein.
Length = 463
Score = 67.7 bits (158), Expect = 4e-11
Identities = 48/190 (25%), Positives = 87/190 (45%), Gaps = 6/190 (3%)
Frame = +2
Query: 122 FVHRFNKNYSSEVEKLRRFKIFQHNLNEIINKNQNDSAKYEINKFSDLSKDETIAKYTGL 301
+V+ + S E R +K + HN + IN Q ++ L+ + I + G
Sbjct: 150 YVNTAHLKNSQEKYSNRLYK-YDHNFVKAINAIQKSWTATTYMEYETLTLGDMIRRSGGH 208
Query: 302 SLPTQTQNFCKVIL-LDQPPGKGPLEFDWRR---LNKVTSVKNQGMCGACWAFATLGSLE 469
S + + Q P +DWR +N V+ V+NQ CG+C++FA++G LE
Sbjct: 209 SRKIPRPKPAPLTAEIQQKILHLPTSWDWRNVHGINFVSPVRNQASCGSCYSFASMGMLE 268
Query: 470 SQFAI--KHNELINLSEQQMIDCDFVDAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADN 643
++ I +++ LS Q+++ C GC GG + + G+ E+ +PY +
Sbjct: 269 ARIRILTNNSQTPILSPQEVVSCSQYAQGCEGGFPYLIAGKYAQDFGLVEEACFPYTGTD 328
Query: 644 NNCRMNSNKF 673
+ C+M + F
Sbjct: 329 SPCKMKEDCF 338
>AF525032-1|AAQ08887.1| 463|Homo sapiens cathepsin C protein.
Length = 463
Score = 66.9 bits (156), Expect = 6e-11
Identities = 48/190 (25%), Positives = 87/190 (45%), Gaps = 6/190 (3%)
Frame = +2
Query: 122 FVHRFNKNYSSEVEKLRRFKIFQHNLNEIINKNQNDSAKYEINKFSDLSKDETIAKYTGL 301
+V+ + S E R +K + HN + IN Q ++ L+ + I + G
Sbjct: 150 YVNTAHLKNSQEKYSNRLYK-YDHNFVKAINAIQKSWTATTYMEYETLTLGDMIRRSGGH 208
Query: 302 SLPTQTQNFCKVIL-LDQPPGKGPLEFDWRR---LNKVTSVKNQGMCGACWAFATLGSLE 469
S + + Q P +DWR +N V+ V+NQ CG+C++FA++G LE
Sbjct: 209 SRKIPRPKPAPLTAEIQQKILHLPTSWDWRNVHGINFVSPVRNQASCGSCYSFASMGMLE 268
Query: 470 SQFAI--KHNELINLSEQQMIDCDFVDAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADN 643
++ I +++ LS Q+++ C GC GG + + G+ E+ +PY +
Sbjct: 269 ARIRILTNNSQTPILSPQEVVSCSQHAQGCEGGFPYLIAGKYAQDFGLVEEACFPYTGTD 328
Query: 644 NNCRMNSNKF 673
+ C+M + F
Sbjct: 329 SPCKMKEDCF 338
>AF234263-1|AAL48191.1| 463|Homo sapiens cathepsin C protein.
Length = 463
Score = 66.9 bits (156), Expect = 6e-11
Identities = 47/181 (25%), Positives = 83/181 (45%), Gaps = 6/181 (3%)
Frame = +2
Query: 149 SSEVEKLRRFKIFQHNLNEIINKNQNDSAKYEINKFSDLSKDETIAKYTGLSLPTQTQNF 328
S E R +K + HN + IN Q ++ L+ + I + G S
Sbjct: 159 SQEKYSNRLYK-YDHNFVKAINAIQKSWTATTYMEYETLTLGDMIRRSGGHSRKIPRPKP 217
Query: 329 CKVIL-LDQPPGKGPLEFDWRR---LNKVTSVKNQGMCGACWAFATLGSLESQFAI--KH 490
+ + Q P +DWR +N V+ V+NQ CG+C++FA++G LE++ I +
Sbjct: 218 APLTAEIQQKILHLPTSWDWRNVHGINFVSPVRNQASCGSCYSFASMGMLEARIRILTNN 277
Query: 491 NELINLSEQQMIDCDFVDAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNCRMNSNK 670
++ LS Q+++ C GC GG + + G+ E+ +PY ++ C+M +
Sbjct: 278 SQTPILSPQEVVSCSQYAQGCEGGFPYLIAGKYAQDFGLVEEACFPYTGTDSPCKMKEDC 337
Query: 671 F 673
F
Sbjct: 338 F 338
>AF234264-1|AAL48192.1| 463|Homo sapiens cathepsin C protein.
Length = 463
Score = 64.1 bits (149), Expect = 4e-10
Identities = 47/190 (24%), Positives = 86/190 (45%), Gaps = 6/190 (3%)
Frame = +2
Query: 122 FVHRFNKNYSSEVEKLRRFKIFQHNLNEIINKNQNDSAKYEINKFSDLSKDETIAKYTGL 301
+V+ + S E R +K + HN + IN Q ++ L+ + I + G
Sbjct: 150 YVNTAHLKNSQEKYSNRLYK-YDHNFVKAINAIQKSWTATTYMEYETLTLGDMIRRSGGH 208
Query: 302 SLPTQTQNFCKVIL-LDQPPGKGPLEFDWRR---LNKVTSVKNQGMCGACWAFATLGSLE 469
S + + Q P + WR +N V+ V+NQ CG+C++FA++G LE
Sbjct: 209 SRKIPRPKPAPLTAEIQQKILHLPTSWYWRNVHGINFVSPVRNQASCGSCYSFASMGMLE 268
Query: 470 SQFAI--KHNELINLSEQQMIDCDFVDAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADN 643
++ I +++ LS Q+++ C GC GG + + G+ E+ +PY +
Sbjct: 269 ARIRILTNNSQTPILSPQEVVSCSQYAQGCEGGFPYLIAGKYAQDFGLVEEACFPYTGTD 328
Query: 644 NNCRMNSNKF 673
+ C+M + F
Sbjct: 329 SPCKMKEDCF 338
>AF254757-1|AAL48195.1| 463|Homo sapiens cathepsin C protein.
Length = 463
Score = 63.3 bits (147), Expect = 8e-10
Identities = 47/190 (24%), Positives = 86/190 (45%), Gaps = 6/190 (3%)
Frame = +2
Query: 122 FVHRFNKNYSSEVEKLRRFKIFQHNLNEIINKNQNDSAKYEINKFSDLSKDETIAKYTGL 301
+V+ + S E R +K + HN + IN Q ++ L+ + I + G
Sbjct: 150 YVNTAHLKNSQEKYSNRLYK-YDHNFVKAINAIQKSWTATTYMEYETLTLGDMIRRSGGH 208
Query: 302 SLPTQTQNFCKVIL-LDQPPGKGPLEFDWRR---LNKVTSVKNQGMCGACWAFATLGSLE 469
S + + Q P +DWR +N V+ V+NQ CG+C++FA++G LE
Sbjct: 209 SRKIPRPKPAPLTAEIQQKILHLPTSWDWRNVHGINFVSPVRNQASCGSCYSFASMGMLE 268
Query: 470 SQFAI--KHNELINLSEQQMIDCDFVDAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADN 643
++ I +++ LS Q+++ GC GG + + G+ E+ +PY +
Sbjct: 269 ARIRILTNNSQTPILSPQEVVSYSQYAQGCEGGFPYLIAGKYAQDFGLVEEACFPYTGTD 328
Query: 644 NNCRMNSNKF 673
+ C+M + F
Sbjct: 329 SPCKMKEDCF 338
>X05256-1|CAA28877.1| 42|Homo sapiens protein ( Human mRNA
fragment for cathepsin L N-terminal/fragment. ).
Length = 42
Score = 54.0 bits (124), Expect = 5e-07
Identities = 21/38 (55%), Positives = 25/38 (65%)
Frame = +2
Query: 362 KGPLEFDWRRLNKVTSVKNQGMCGACWAFATLGSLESQ 475
+ P DWR VT VKNQG CG+CWAF+ G+LE Q
Sbjct: 1 EAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQ 38
>M14221-1|AAA52129.1| 339|Homo sapiens CTSB protein.
Length = 339
Score = 45.6 bits (103), Expect = 2e-04
Identities = 22/75 (29%), Positives = 37/75 (49%), Gaps = 8/75 (10%)
Frame = +2
Query: 362 KGPLEFD----WRRLNKVTSVKNQGMCGACWAFATLGSLESQFAIKHNE--LINLSEQQM 523
K P FD W + + +++QG CG+CWAF + ++ + I N + +S + +
Sbjct: 79 KLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDL 138
Query: 524 IDC--DFVDAGCNGG 562
+ C GCNGG
Sbjct: 139 LTCCGSMCGDGCNGG 153
>L16510-1|AAC37547.1| 339|Homo sapiens cathepsin B protein.
Length = 339
Score = 45.6 bits (103), Expect = 2e-04
Identities = 22/75 (29%), Positives = 37/75 (49%), Gaps = 8/75 (10%)
Frame = +2
Query: 362 KGPLEFD----WRRLNKVTSVKNQGMCGACWAFATLGSLESQFAIKHNE--LINLSEQQM 523
K P FD W + + +++QG CG+CWAF + ++ + I N + +S + +
Sbjct: 79 KLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDL 138
Query: 524 IDC--DFVDAGCNGG 562
+ C GCNGG
Sbjct: 139 LTCCGSMCGDGCNGG 153
>BC095408-1|AAH95408.1| 339|Homo sapiens cathepsin B protein.
Length = 339
Score = 45.6 bits (103), Expect = 2e-04
Identities = 22/75 (29%), Positives = 37/75 (49%), Gaps = 8/75 (10%)
Frame = +2
Query: 362 KGPLEFD----WRRLNKVTSVKNQGMCGACWAFATLGSLESQFAIKHNE--LINLSEQQM 523
K P FD W + + +++QG CG+CWAF + ++ + I N + +S + +
Sbjct: 79 KLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDL 138
Query: 524 IDC--DFVDAGCNGG 562
+ C GCNGG
Sbjct: 139 LTCCGSMCGDGCNGG 153
>BC010240-1|AAH10240.1| 339|Homo sapiens cathepsin B protein.
Length = 339
Score = 45.6 bits (103), Expect = 2e-04
Identities = 22/75 (29%), Positives = 37/75 (49%), Gaps = 8/75 (10%)
Frame = +2
Query: 362 KGPLEFD----WRRLNKVTSVKNQGMCGACWAFATLGSLESQFAIKHNE--LINLSEQQM 523
K P FD W + + +++QG CG+CWAF + ++ + I N + +S + +
Sbjct: 79 KLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDL 138
Query: 524 IDC--DFVDAGCNGG 562
+ C GCNGG
Sbjct: 139 LTCCGSMCGDGCNGG 153
>BC070278-1|AAH70278.1| 476|Homo sapiens tubulointerstitial
nephritis antigen protein.
Length = 476
Score = 41.5 bits (93), Expect = 0.003
Identities = 32/90 (35%), Positives = 41/90 (45%), Gaps = 7/90 (7%)
Frame = +2
Query: 416 NQGMCGACWAFATLGSLESQFAI--KHNELINLSEQQMIDCDFVDA-GCNGGLLHTAFEA 586
+Q C A WAF+T + AI K NLS Q +I C + GCN G + A+
Sbjct: 236 DQKNCAASWAFSTASVAADRIAIQSKGRYTANLSPQNLISCCAKNRHGCNSGSIDRAWWY 295
Query: 587 IIKMGGVQLESDYP----YEADNNNCRMNS 664
+ K G V + YP A NN C M S
Sbjct: 296 LRKRGLVS-HACYPLFKDQNATNNGCAMAS 324
>AL589946-2|CAH70302.1| 476|Homo sapiens tubulointerstitial
nephritis antigen protein.
Length = 476
Score = 41.5 bits (93), Expect = 0.003
Identities = 32/90 (35%), Positives = 41/90 (45%), Gaps = 7/90 (7%)
Frame = +2
Query: 416 NQGMCGACWAFATLGSLESQFAI--KHNELINLSEQQMIDCDFVDA-GCNGGLLHTAFEA 586
+Q C A WAF+T + AI K NLS Q +I C + GCN G + A+
Sbjct: 236 DQKNCAASWAFSTASVAADRIAIQSKGRYTANLSPQNLISCCAKNRHGCNSGSIDRAWWY 295
Query: 587 IIKMGGVQLESDYP----YEADNNNCRMNS 664
+ K G V + YP A NN C M S
Sbjct: 296 LRKRGLVS-HACYPLFKDQNATNNGCAMAS 324
>AL359380-5|CAI16272.1| 476|Homo sapiens tubulointerstitial
nephritis antigen protein.
Length = 476
Score = 41.5 bits (93), Expect = 0.003
Identities = 32/90 (35%), Positives = 41/90 (45%), Gaps = 7/90 (7%)
Frame = +2
Query: 416 NQGMCGACWAFATLGSLESQFAI--KHNELINLSEQQMIDCDFVDA-GCNGGLLHTAFEA 586
+Q C A WAF+T + AI K NLS Q +I C + GCN G + A+
Sbjct: 236 DQKNCAASWAFSTASVAADRIAIQSKGRYTANLSPQNLISCCAKNRHGCNSGSIDRAWWY 295
Query: 587 IIKMGGVQLESDYP----YEADNNNCRMNS 664
+ K G V + YP A NN C M S
Sbjct: 296 LRKRGLVS-HACYPLFKDQNATNNGCAMAS 324
>AF195116-1|AAF08931.1| 476|Homo sapiens tubulointerstitial
nephritis antigen isoform TIN-ag protein.
Length = 476
Score = 41.5 bits (93), Expect = 0.003
Identities = 32/90 (35%), Positives = 41/90 (45%), Gaps = 7/90 (7%)
Frame = +2
Query: 416 NQGMCGACWAFATLGSLESQFAI--KHNELINLSEQQMIDCDFVDA-GCNGGLLHTAFEA 586
+Q C A WAF+T + AI K NLS Q +I C + GCN G + A+
Sbjct: 236 DQKNCAASWAFSTASVAADRIAIQSKGRYTANLSPQNLISCCAKNRHGCNSGSIDRAWWY 295
Query: 587 IIKMGGVQLESDYP----YEADNNNCRMNS 664
+ K G V + YP A NN C M S
Sbjct: 296 LRKRGLVS-HACYPLFKDQNATNNGCAMAS 324
>AB022277-1|BAA84949.1| 476|Homo sapiens tubulointerstitial
nephritis antigen protein.
Length = 476
Score = 41.5 bits (93), Expect = 0.003
Identities = 32/90 (35%), Positives = 41/90 (45%), Gaps = 7/90 (7%)
Frame = +2
Query: 416 NQGMCGACWAFATLGSLESQFAI--KHNELINLSEQQMIDCDFVDA-GCNGGLLHTAFEA 586
+Q C A WAF+T + AI K NLS Q +I C + GCN G + A+
Sbjct: 236 DQKNCAASWAFSTASVAADRIAIQSKGRYTANLSPQNLISCCAKNRHGCNSGSIDRAWWY 295
Query: 587 IIKMGGVQLESDYP----YEADNNNCRMNS 664
+ K G V + YP A NN C M S
Sbjct: 296 LRKRGLVS-HACYPLFKDQNATNNGCAMAS 324
>Y18460-1|CAA77178.1| 195|Homo sapiens cathepsin B protein.
Length = 195
Score = 39.9 bits (89), Expect = 0.008
Identities = 15/47 (31%), Positives = 25/47 (53%), Gaps = 2/47 (4%)
Frame = +2
Query: 428 CGACWAFATLGSLESQFAIKHNELINLSEQQMIDC--DFVDAGCNGG 562
CG+CWAF + ++ + I N + +S + ++ C GCNGG
Sbjct: 1 CGSCWAFGAVEAISDRICIHTNVSVEVSAEDLLTCCGSMCGDGCNGG 47
>BT019915-1|AAV38718.1| 303|Homo sapiens cathepsin Z protein.
Length = 303
Score = 39.5 bits (88), Expect = 0.011
Identities = 32/109 (29%), Positives = 51/109 (46%), Gaps = 10/109 (9%)
Frame = +2
Query: 356 PGKGPLEFDWRRL---NKVTSVKNQGM---CGACWAFATLGSLESQFAIKHN---ELINL 508
P P +DWR + N + +NQ + CG+CWA A+ ++ + IK L
Sbjct: 59 PADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLL 118
Query: 509 SEQQMIDCDFVDAG-CNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNC 652
S Q +IDC +AG C GG + ++ G+ E+ Y+A + C
Sbjct: 119 SVQNVIDCG--NAGSCEGGNDLSVWD-YAHQHGIPDETCNNYQAKDQEC 164
>BC042168-1|AAH42168.1| 303|Homo sapiens cathepsin Z protein.
Length = 303
Score = 39.5 bits (88), Expect = 0.011
Identities = 32/109 (29%), Positives = 51/109 (46%), Gaps = 10/109 (9%)
Frame = +2
Query: 356 PGKGPLEFDWRRL---NKVTSVKNQGM---CGACWAFATLGSLESQFAIKHN---ELINL 508
P P +DWR + N + +NQ + CG+CWA A+ ++ + IK L
Sbjct: 59 PADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLL 118
Query: 509 SEQQMIDCDFVDAG-CNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNC 652
S Q +IDC +AG C GG + ++ G+ E+ Y+A + C
Sbjct: 119 SVQNVIDCG--NAGSCEGGNDLSVWD-YAHQHGIPDETCNNYQAKDQEC 164
>BC025419-1|AAH25419.1| 297|Homo sapiens CTSZ protein protein.
Length = 297
Score = 39.5 bits (88), Expect = 0.011
Identities = 32/109 (29%), Positives = 51/109 (46%), Gaps = 10/109 (9%)
Frame = +2
Query: 356 PGKGPLEFDWRRL---NKVTSVKNQGM---CGACWAFATLGSLESQFAIKHN---ELINL 508
P P +DWR + N + +NQ + CG+CWA A+ ++ + IK L
Sbjct: 59 PADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLL 118
Query: 509 SEQQMIDCDFVDAG-CNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNC 652
S Q +IDC +AG C GG + ++ G+ E+ Y+A + C
Sbjct: 119 SVQNVIDCG--NAGSCEGGNDLSVWD-YAHQHGIPDETCNNYQAKDQEC 164
>AL109840-6|CAC09370.1| 303|Homo sapiens cathepsin Z protein.
Length = 303
Score = 39.5 bits (88), Expect = 0.011
Identities = 32/109 (29%), Positives = 51/109 (46%), Gaps = 10/109 (9%)
Frame = +2
Query: 356 PGKGPLEFDWRRL---NKVTSVKNQGM---CGACWAFATLGSLESQFAIKHN---ELINL 508
P P +DWR + N + +NQ + CG+CWA A+ ++ + IK L
Sbjct: 59 PADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLL 118
Query: 509 SEQQMIDCDFVDAG-CNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNC 652
S Q +IDC +AG C GG + ++ G+ E+ Y+A + C
Sbjct: 119 SVQNVIDCG--NAGSCEGGNDLSVWD-YAHQHGIPDETCNNYQAKDQEC 164
>AF136276-1|AAF13148.1| 303|Homo sapiens cathepsin Z precursor
protein.
Length = 303
Score = 39.5 bits (88), Expect = 0.011
Identities = 32/109 (29%), Positives = 51/109 (46%), Gaps = 10/109 (9%)
Frame = +2
Query: 356 PGKGPLEFDWRRL---NKVTSVKNQGM---CGACWAFATLGSLESQFAIKHN---ELINL 508
P P +DWR + N + +NQ + CG+CWA A+ ++ + IK L
Sbjct: 59 PADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLL 118
Query: 509 SEQQMIDCDFVDAG-CNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNC 652
S Q +IDC +AG C GG + ++ G+ E+ Y+A + C
Sbjct: 119 SVQNVIDCG--NAGSCEGGNDLSVWD-YAHQHGIPDETCNNYQAKDQEC 164
>AF136273-1|AAF13145.1| 303|Homo sapiens cathepsin Z precursor
protein.
Length = 303
Score = 39.5 bits (88), Expect = 0.011
Identities = 32/109 (29%), Positives = 51/109 (46%), Gaps = 10/109 (9%)
Frame = +2
Query: 356 PGKGPLEFDWRRL---NKVTSVKNQGM---CGACWAFATLGSLESQFAIKHN---ELINL 508
P P +DWR + N + +NQ + CG+CWA A+ ++ + IK L
Sbjct: 59 PADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLL 118
Query: 509 SEQQMIDCDFVDAG-CNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNC 652
S Q +IDC +AG C GG + ++ G+ E+ Y+A + C
Sbjct: 119 SVQNVIDCG--NAGSCEGGNDLSVWD-YAHQHGIPDETCNNYQAKDQEC 164
>AF032906-1|AAC39839.1| 303|Homo sapiens cathepsin Z precursor
protein.
Length = 303
Score = 39.5 bits (88), Expect = 0.011
Identities = 32/109 (29%), Positives = 51/109 (46%), Gaps = 10/109 (9%)
Frame = +2
Query: 356 PGKGPLEFDWRRL---NKVTSVKNQGM---CGACWAFATLGSLESQFAIKHN---ELINL 508
P P +DWR + N + +NQ + CG+CWA A+ ++ + IK L
Sbjct: 59 PADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLL 118
Query: 509 SEQQMIDCDFVDAG-CNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNC 652
S Q +IDC +AG C GG + ++ G+ E+ Y+A + C
Sbjct: 119 SVQNVIDCG--NAGSCEGGNDLSVWD-YAHQHGIPDETCNNYQAKDQEC 164
>AF009923-1|AAC63141.1| 293|Homo sapiens preprocathepsin P protein.
Length = 293
Score = 39.5 bits (88), Expect = 0.011
Identities = 32/109 (29%), Positives = 51/109 (46%), Gaps = 10/109 (9%)
Frame = +2
Query: 356 PGKGPLEFDWRRL---NKVTSVKNQGM---CGACWAFATLGSLESQFAIKHN---ELINL 508
P P +DWR + N + +NQ + CG+CWA A+ ++ + IK L
Sbjct: 49 PADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLL 108
Query: 509 SEQQMIDCDFVDAG-CNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNC 652
S Q +IDC +AG C GG + ++ G+ E+ Y+A + C
Sbjct: 109 SVQNVIDCG--NAGSCEGGNDLSVWD-YAHQHGIPDETCNNYQAKDQEC 154
>AF073890-1|AAC61477.1| 303|Homo sapiens cathepsin X precursor
protein.
Length = 303
Score = 38.7 bits (86), Expect = 0.019
Identities = 30/108 (27%), Positives = 48/108 (44%), Gaps = 9/108 (8%)
Frame = +2
Query: 356 PGKGPLEFDWRRL---NKVTSVKNQGM---CGACWAFATLGSLESQFAIKHN---ELINL 508
P P +DWR + N + +NQ + CG+CWA A+ ++ + IK L
Sbjct: 59 PADLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLL 118
Query: 509 SEQQMIDCDFVDAGCNGGLLHTAFEAIIKMGGVQLESDYPYEADNNNC 652
S Q +IDC C GG + ++ G+ E+ Y+A + C
Sbjct: 119 SVQNVIDCG-NRGSCEGGNDLSVWD-YAHQHGISDETCNNYQAKDQEC 164
>BC064633-1|AAH64633.1| 467|Homo sapiens tubulointerstitial
nephritis antigen-like 1 protein.
Length = 467
Score = 37.1 bits (82), Expect = 0.058
Identities = 35/133 (26%), Positives = 56/133 (42%), Gaps = 7/133 (5%)
Frame = +2
Query: 254 FSDLSKDETIAKYTGLSLPTQT-QNFCKVILLDQPPGKGPLEFDWRRL--NKVTSVKNQG 424
F ++ DE I G P+ + N ++ + P P F+ N + +QG
Sbjct: 165 FWGMTLDEGIRYRLGTIRPSSSVMNMHEIYTVLNPGEVLPTAFEASEKWPNLIHEPLDQG 224
Query: 425 MCGACWAFATLGSLESQFAIK---HNELINLSEQQMIDCD-FVDAGCNGGLLHTAFEAII 592
C WAF+T + +I H + LS Q ++ CD GC GG L A+ +
Sbjct: 225 NCAGSWAFSTAAVASDRVSIHSLGHMTPV-LSPQNLLSCDTHQQQGCRGGRLDGAW-WFL 282
Query: 593 KMGGVQLESDYPY 631
+ GV + YP+
Sbjct: 283 RRRGVVSDHCYPF 295
>AY358421-1|AAQ88787.1| 467|Homo sapiens LCN7 protein.
Length = 467
Score = 37.1 bits (82), Expect = 0.058
Identities = 35/133 (26%), Positives = 56/133 (42%), Gaps = 7/133 (5%)
Frame = +2
Query: 254 FSDLSKDETIAKYTGLSLPTQT-QNFCKVILLDQPPGKGPLEFDWRRL--NKVTSVKNQG 424
F ++ DE I G P+ + N ++ + P P F+ N + +QG
Sbjct: 165 FWGMTLDEGIRYRLGTIRPSSSVMNMHEIYTVLNPGEVLPTAFEASEKWPNLIHEPLDQG 224
Query: 425 MCGACWAFATLGSLESQFAIK---HNELINLSEQQMIDCD-FVDAGCNGGLLHTAFEAII 592
C WAF+T + +I H + LS Q ++ CD GC GG L A+ +
Sbjct: 225 NCAGSWAFSTAAVASDRVSIHSLGHMTPV-LSPQNLLSCDTHQQQGCRGGRLDGAW-WFL 282
Query: 593 KMGGVQLESDYPY 631
+ GV + YP+
Sbjct: 283 RRRGVVSDHCYPF 295
>AK075398-1|BAC11596.1| 467|Homo sapiens protein ( Homo sapiens
cDNA PSEC0088 fis, clone PLACE1001098, highly similar to
P3ECSL; glucocorticoid-inducible protein. ).
Length = 467
Score = 37.1 bits (82), Expect = 0.058
Identities = 35/133 (26%), Positives = 56/133 (42%), Gaps = 7/133 (5%)
Frame = +2
Query: 254 FSDLSKDETIAKYTGLSLPTQT-QNFCKVILLDQPPGKGPLEFDWRRL--NKVTSVKNQG 424
F ++ DE I G P+ + N ++ + P P F+ N + +QG
Sbjct: 165 FWGMTLDEGIRYRLGTIRPSSSVMNMHEIYTVLNPGEVLPTAFEASEKWPNLIHEPLDQG 224
Query: 425 MCGACWAFATLGSLESQFAIK---HNELINLSEQQMIDCD-FVDAGCNGGLLHTAFEAII 592
C WAF+T + +I H + LS Q ++ CD GC GG L A+ +
Sbjct: 225 NCAGSWAFSTAAVASDRVSIHSLGHMTPV-LSPQNLLSCDTHQQQGCRGGRLDGAW-WFL 282
Query: 593 KMGGVQLESDYPY 631
+ GV + YP+
Sbjct: 283 RRRGVVSDHCYPF 295
>AF236155-1|AAG40154.1| 467|Homo sapiens tubulointerstitial
nephritis antigen-related protein protein.
Length = 467
Score = 37.1 bits (82), Expect = 0.058
Identities = 35/133 (26%), Positives = 56/133 (42%), Gaps = 7/133 (5%)
Frame = +2
Query: 254 FSDLSKDETIAKYTGLSLPTQT-QNFCKVILLDQPPGKGPLEFDWRRL--NKVTSVKNQG 424
F ++ DE I G P+ + N ++ + P P F+ N + +QG
Sbjct: 165 FWGMTLDEGIRYRLGTIRPSSSVMNMHEIYTVLNPGEVLPTAFEASEKWPNLIHEPLDQG 224
Query: 425 MCGACWAFATLGSLESQFAIK---HNELINLSEQQMIDCD-FVDAGCNGGLLHTAFEAII 592
C WAF+T + +I H + LS Q ++ CD GC GG L A+ +
Sbjct: 225 NCAGSWAFSTAAVASDRVSIHSLGHMTPV-LSPQNLLSCDTHQQQGCRGGRLDGAW-WFL 282
Query: 593 KMGGVQLESDYPY 631
+ GV + YP+
Sbjct: 283 RRRGVVSDHCYPF 295
>AF236150-1|AAG38876.1| 467|Homo sapiens tubulointerstitial
nephritis antigen-related protein precursor protein.
Length = 467
Score = 37.1 bits (82), Expect = 0.058
Identities = 35/133 (26%), Positives = 56/133 (42%), Gaps = 7/133 (5%)
Frame = +2
Query: 254 FSDLSKDETIAKYTGLSLPTQT-QNFCKVILLDQPPGKGPLEFDWRRL--NKVTSVKNQG 424
F ++ DE I G P+ + N ++ + P P F+ N + +QG
Sbjct: 165 FWGMTLDEGIRYRLGTIRPSSSVMNMHEIYTVLNPGEVLPTAFEASEKWPNLIHEPLDQG 224
Query: 425 MCGACWAFATLGSLESQFAIK---HNELINLSEQQMIDCD-FVDAGCNGGLLHTAFEAII 592
C WAF+T + +I H + LS Q ++ CD GC GG L A+ +
Sbjct: 225 NCAGSWAFSTAAVASDRVSIHSLGHMTPV-LSPQNLLSCDTHQQQGCRGGRLDGAW-WFL 282
Query: 593 KMGGVQLESDYPY 631
+ GV + YP+
Sbjct: 283 RRRGVVSDHCYPF 295
>AF205436-1|AAG33699.1| 467|Homo sapiens oxidized-LDL responsive
gene 2 protein.
Length = 467
Score = 37.1 bits (82), Expect = 0.058
Identities = 35/133 (26%), Positives = 56/133 (42%), Gaps = 7/133 (5%)
Frame = +2
Query: 254 FSDLSKDETIAKYTGLSLPTQT-QNFCKVILLDQPPGKGPLEFDWRRL--NKVTSVKNQG 424
F ++ DE I G P+ + N ++ + P P F+ N + +QG
Sbjct: 165 FWGMTLDEGIRYRLGTIRPSSSVMNMHEIYTVLNPGEVLPTAFEASEKWPNLIHEPLDQG 224
Query: 425 MCGACWAFATLGSLESQFAIK---HNELINLSEQQMIDCD-FVDAGCNGGLLHTAFEAII 592
C WAF+T + +I H + LS Q ++ CD GC GG L A+ +
Sbjct: 225 NCAGSWAFSTAAVASDRVSIHSLGHMTPV-LSPQNLLSCDTHQQQGCRGGRLDGAW-WFL 282
Query: 593 KMGGVQLESDYPY 631
+ GV + YP+
Sbjct: 283 RRRGVVSDHCYPF 295
>AB050719-1|BAB18727.1| 467|Homo sapiens glucocorticoid-inducible
protein protein.
Length = 467
Score = 37.1 bits (82), Expect = 0.058
Identities = 35/133 (26%), Positives = 56/133 (42%), Gaps = 7/133 (5%)
Frame = +2
Query: 254 FSDLSKDETIAKYTGLSLPTQT-QNFCKVILLDQPPGKGPLEFDWRRL--NKVTSVKNQG 424
F ++ DE I G P+ + N ++ + P P F+ N + +QG
Sbjct: 165 FWGMTLDEGIRYRLGTIRPSSSVMNMHEIYTVLNPGEVLPTAFEASEKWPNLIHEPLDQG 224
Query: 425 MCGACWAFATLGSLESQFAIK---HNELINLSEQQMIDCD-FVDAGCNGGLLHTAFEAII 592
C WAF+T + +I H + LS Q ++ CD GC GG L A+ +
Sbjct: 225 NCAGSWAFSTAAVASDRVSIHSLGHMTPV-LSPQNLLSCDTHQQQGCRGGRLDGAW-WFL 282
Query: 593 KMGGVQLESDYPY 631
+ GV + YP+
Sbjct: 283 RRRGVVSDHCYPF 295
>AB050716-1|BAB18636.1| 467|Homo sapiens glucocorticoid-inducible
protein protein.
Length = 467
Score = 37.1 bits (82), Expect = 0.058
Identities = 35/133 (26%), Positives = 56/133 (42%), Gaps = 7/133 (5%)
Frame = +2
Query: 254 FSDLSKDETIAKYTGLSLPTQT-QNFCKVILLDQPPGKGPLEFDWRRL--NKVTSVKNQG 424
F ++ DE I G P+ + N ++ + P P F+ N + +QG
Sbjct: 165 FWGMTLDEGIRYRLGTIRPSSSVMNMHEIYTVLNPGEVLPTAFEASEKWPNLIHEPLDQG 224
Query: 425 MCGACWAFATLGSLESQFAIK---HNELINLSEQQMIDCD-FVDAGCNGGLLHTAFEAII 592
C WAF+T + +I H + LS Q ++ CD GC GG L A+ +
Sbjct: 225 NCAGSWAFSTAAVASDRVSIHSLGHMTPV-LSPQNLLSCDTHQQQGCRGGRLDGAW-WFL 282
Query: 593 KMGGVQLESDYPY 631
+ GV + YP+
Sbjct: 283 RRRGVVSDHCYPF 295
>AK074124-1|BAB84950.1| 284|Homo sapiens FLJ00196 protein protein.
Length = 284
Score = 33.5 bits (73), Expect = 0.72
Identities = 22/73 (30%), Positives = 33/73 (45%), Gaps = 4/73 (5%)
Frame = +2
Query: 395 NKVTSVKNQGMCGACWAFATLGSLESQFAIK---HNELINLSEQQMIDCD-FVDAGCNGG 562
N + +QG C WAF+T + +I H + LS Q ++ CD GC GG
Sbjct: 81 NLIHEPLDQGNCAGSWAFSTAAVASDRVSIHSLGHMTPV-LSPQNLLSCDTHQQQGCRGG 139
Query: 563 LLHTAFEAIIKMG 601
L A+ + + G
Sbjct: 140 RLDGAWWFLRRRG 152
>AF217997-1|AAG17239.1| 151|Homo sapiens unknown protein.
Length = 151
Score = 31.9 bits (69), Expect = 2.2
Identities = 12/29 (41%), Positives = 17/29 (58%)
Frame = +2
Query: 575 AFEAIIKMGGVQLESDYPYEADNNNCRMN 661
AF+ + GG+ E YPYEA +C+ N
Sbjct: 4 AFQYVQDNGGLDSEESYPYEATEESCKYN 32
>BC089428-1|AAH89428.1| 1192|Homo sapiens PLEKHG1 protein protein.
Length = 1192
Score = 30.7 bits (66), Expect = 5.0
Identities = 13/36 (36%), Positives = 20/36 (55%)
Frame = +2
Query: 467 ESQFAIKHNELINLSEQQMIDCDFVDAGCNGGLLHT 574
ES+ + HN S+ + +D DF D C+G LH+
Sbjct: 1096 ESELELSHNRR-RKSDSKFVDADFSDNVCSGNTLHS 1130
>AL450339-2|CAI12939.1| 1385|Homo sapiens pleckstrin homology domain
containing, family G (with RhoGef domain) member 1
protein.
Length = 1385
Score = 30.7 bits (66), Expect = 5.0
Identities = 13/36 (36%), Positives = 20/36 (55%)
Frame = +2
Query: 467 ESQFAIKHNELINLSEQQMIDCDFVDAGCNGGLLHT 574
ES+ + HN S+ + +D DF D C+G LH+
Sbjct: 1289 ESELELSHNRR-RKSDSKFVDADFSDNVCSGNTLHS 1323
>AL035086-3|CAI42790.1| 1385|Homo sapiens pleckstrin homology domain
containing, family G (with RhoGef domain) member 1
protein.
Length = 1385
Score = 30.7 bits (66), Expect = 5.0
Identities = 13/36 (36%), Positives = 20/36 (55%)
Frame = +2
Query: 467 ESQFAIKHNELINLSEQQMIDCDFVDAGCNGGLLHT 574
ES+ + HN S+ + +D DF D C+G LH+
Sbjct: 1289 ESELELSHNRR-RKSDSKFVDADFSDNVCSGNTLHS 1323
>AB033035-1|BAA86523.1| 1113|Homo sapiens KIAA1209 protein protein.
Length = 1113
Score = 30.7 bits (66), Expect = 5.0
Identities = 13/36 (36%), Positives = 20/36 (55%)
Frame = +2
Query: 467 ESQFAIKHNELINLSEQQMIDCDFVDAGCNGGLLHT 574
ES+ + HN S+ + +D DF D C+G LH+
Sbjct: 1017 ESELELSHNRR-RKSDSKFVDADFSDNVCSGNTLHS 1051
>BX640701-1|CAE45821.1| 477|Homo sapiens hypothetical protein
protein.
Length = 477
Score = 29.9 bits (64), Expect = 8.8
Identities = 21/58 (36%), Positives = 34/58 (58%), Gaps = 1/58 (1%)
Frame = +2
Query: 137 NKNYSSEVEKLRRFKIFQHNLNEIINKNQNDSAKYEINKFSDLSKDETI-AKYTGLSL 307
+KNYS +E L+ +H+L+ + +K A+YE+ K S L D+TI A T ++L
Sbjct: 61 DKNYSVNLENLKNLHKKRHHLSTVTSKG---FAQYELFKSSAL--DDTITASQTAIAL 113
>BC090041-1|AAH90041.1| 477|Homo sapiens ZWILCH protein protein.
Length = 477
Score = 29.9 bits (64), Expect = 8.8
Identities = 21/58 (36%), Positives = 34/58 (58%), Gaps = 1/58 (1%)
Frame = +2
Query: 137 NKNYSSEVEKLRRFKIFQHNLNEIINKNQNDSAKYEINKFSDLSKDETI-AKYTGLSL 307
+KNYS +E L+ +H+L+ + +K A+YE+ K S L D+TI A T ++L
Sbjct: 61 DKNYSVNLENLKNLHKKRHHLSTVTSKG---FAQYELFKSSAL--DDTITASQTAIAL 113
>BC036900-1|AAH36900.1| 477|Homo sapiens ZWILCH protein protein.
Length = 477
Score = 29.9 bits (64), Expect = 8.8
Identities = 21/58 (36%), Positives = 34/58 (58%), Gaps = 1/58 (1%)
Frame = +2
Query: 137 NKNYSSEVEKLRRFKIFQHNLNEIINKNQNDSAKYEINKFSDLSKDETI-AKYTGLSL 307
+KNYS +E L+ +H+L+ + +K A+YE+ K S L D+TI A T ++L
Sbjct: 61 DKNYSVNLENLKNLHKKRHHLSTVTSKG---FAQYELFKSSAL--DDTITASQTAIAL 113
>AK023175-1|BAB14446.1| 591|Homo sapiens protein ( Homo sapiens
cDNA FLJ13113 fis, clone NT2RP3002590. ).
Length = 591
Score = 29.9 bits (64), Expect = 8.8
Identities = 21/58 (36%), Positives = 34/58 (58%), Gaps = 1/58 (1%)
Frame = +2
Query: 137 NKNYSSEVEKLRRFKIFQHNLNEIINKNQNDSAKYEINKFSDLSKDETI-AKYTGLSL 307
+KNYS +E L+ +H+L+ + +K A+YE+ K S L D+TI A T ++L
Sbjct: 175 DKNYSVNLENLKNLHKKRHHLSTVTSKG---FAQYELFKSSAL--DDTITASQTAIAL 227
>AK000898-1|BAA91414.1| 134|Homo sapiens protein ( Homo sapiens
cDNA FLJ10036 fis, clone HEMBA1000946. ).
Length = 134
Score = 29.9 bits (64), Expect = 8.8
Identities = 21/58 (36%), Positives = 34/58 (58%), Gaps = 1/58 (1%)
Frame = +2
Query: 137 NKNYSSEVEKLRRFKIFQHNLNEIINKNQNDSAKYEINKFSDLSKDETI-AKYTGLSL 307
+KNYS +E L+ +H+L+ + +K A+YE+ K S L D+TI A T ++L
Sbjct: 61 DKNYSVNLENLKNLHKKRHHLSTVTSKG---FAQYELFKSSAL--DDTITASQTAIAL 113
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 90,032,418
Number of Sequences: 237096
Number of extensions: 1771575
Number of successful extensions: 4711
Number of sequences better than 10.0: 102
Number of HSP's better than 10.0 without gapping: 4535
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4655
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 7783251346
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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