Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= bmnc1c05
(782 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Y14487-1|CAB54840.1| 347|Homo sapiens cytosolic serine hydroxym... 359 8e-99
Y14485-1|CAB54838.1| 483|Homo sapiens cytosolic serine hydroxym... 359 8e-99
L23928-3|AAA36019.1| 403|Homo sapiens serine hydroxymethyltrans... 359 8e-99
L23928-2|AAA36018.1| 444|Homo sapiens serine hydroxymethyltrans... 359 8e-99
L23928-1|AAA36020.1| 483|Homo sapiens serine hydroxymethyltrans... 359 8e-99
L11931-1|AAA63257.1| 483|Homo sapiens serine hydroxymethyltrans... 359 8e-99
BC038598-1|AAH38598.1| 483|Homo sapiens serine hydroxymethyltra... 359 8e-99
BC022874-1|AAH22874.1| 444|Homo sapiens serine hydroxymethyltra... 359 8e-99
BC007979-1|AAH07979.1| 483|Homo sapiens serine hydroxymethyltra... 359 8e-99
AK223552-1|BAD97272.1| 483|Homo sapiens serine hydroxymethyltra... 359 8e-99
U23143-1|AAA64572.1| 483|Homo sapiens mitochondrial serine hydr... 328 1e-89
L11932-1|AAA63258.1| 474|Homo sapiens serine hydroxymethyltrans... 328 1e-89
BT006866-1|AAP35512.1| 504|Homo sapiens serine hydroxymethyltra... 328 1e-89
BC044211-1|AAH44211.1| 504|Homo sapiens serine hydroxymethyltra... 328 1e-89
BC013677-1|AAH13677.1| 504|Homo sapiens serine hydroxymethyltra... 328 1e-89
BC011911-1|AAH11911.1| 504|Homo sapiens serine hydroxymethyltra... 328 1e-89
AK223555-1|BAD97275.1| 504|Homo sapiens serine hydroxymethyltra... 328 1e-89
BC032584-1|AAH32584.1| 494|Homo sapiens SHMT2 protein protein. 299 5e-81
BC091501-1|AAH91501.1| 480|Homo sapiens SHMT2 protein protein. 263 6e-70
Y14486-1|CAB54839.1| 310|Homo sapiens cytosolic serine hydroxym... 121 3e-27
Y14488-1|CAB54841.1| 129|Homo sapiens 14 kDa protein protein. 55 3e-07
AK055053-1|BAB70847.1| 135|Homo sapiens protein. 40 0.013
>Y14487-1|CAB54840.1| 347|Homo sapiens cytosolic serine
hydroxymethyltransferase protein.
Length = 347
Score = 359 bits (882), Expect = 8e-99
Identities = 165/229 (72%), Positives = 193/229 (84%)
Frame = +1
Query: 91 KLLNSNLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPN 270
K+L L ++D E+++II KE +RQR GLE+IASENF S VL+ L SCL+NKYSEG P
Sbjct: 20 KMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPG 79
Query: 271 QRYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIM 450
QRYYGG E+IDE+E L Q R+L+AY+L + WGVNVQPYSGSPANFAVYT +VEPHGRIM
Sbjct: 80 QRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIM 139
Query: 451 GLDLPDGGHLTHGFFTATKKISATSIFFESMPYKVDPKSGLIDYDKLAETAKLFKPRLII 630
GLDLPDGGHLTHGF T KKISATSIFFESMPYKV+P +G I+YD+L E A+LF P+LII
Sbjct: 140 GLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLII 199
Query: 631 AGMSCYSRCLDYKRFREIADANGAYLMADMAHVSGLVAAGVIPSPFEYC 777
AG SCYSR L+Y R R+IAD NGAYLMADMAH+SGLVAAGV+PSPFE+C
Sbjct: 200 AGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHC 248
>Y14485-1|CAB54838.1| 483|Homo sapiens cytosolic serine
hydroxymethyltransferase protein.
Length = 483
Score = 359 bits (882), Expect = 8e-99
Identities = 165/229 (72%), Positives = 193/229 (84%)
Frame = +1
Query: 91 KLLNSNLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPN 270
K+L L ++D E+++II KE +RQR GLE+IASENF S VL+ L SCL+NKYSEG P
Sbjct: 20 KMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPG 79
Query: 271 QRYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIM 450
QRYYGG E+IDE+E L Q R+L+AY+L + WGVNVQPYSGSPANFAVYT +VEPHGRIM
Sbjct: 80 QRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIM 139
Query: 451 GLDLPDGGHLTHGFFTATKKISATSIFFESMPYKVDPKSGLIDYDKLAETAKLFKPRLII 630
GLDLPDGGHLTHGF T KKISATSIFFESMPYKV+P +G I+YD+L E A+LF P+LII
Sbjct: 140 GLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLII 199
Query: 631 AGMSCYSRCLDYKRFREIADANGAYLMADMAHVSGLVAAGVIPSPFEYC 777
AG SCYSR L+Y R R+IAD NGAYLMADMAH+SGLVAAGV+PSPFE+C
Sbjct: 200 AGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHC 248
>L23928-3|AAA36019.1| 403|Homo sapiens serine
hydroxymethyltransferase protein.
Length = 403
Score = 359 bits (882), Expect = 8e-99
Identities = 165/229 (72%), Positives = 193/229 (84%)
Frame = +1
Query: 91 KLLNSNLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPN 270
K+L L ++D E+++II KE +RQR GLE+IASENF S VL+ L SCL+NKYSEG P
Sbjct: 20 KMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPG 79
Query: 271 QRYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIM 450
QRYYGG E+IDE+E L Q R+L+AY+L + WGVNVQPYSGSPANFAVYT +VEPHGRIM
Sbjct: 80 QRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIM 139
Query: 451 GLDLPDGGHLTHGFFTATKKISATSIFFESMPYKVDPKSGLIDYDKLAETAKLFKPRLII 630
GLDLPDGGHLTHGF T KKISATSIFFESMPYKV+P +G I+YD+L E A+LF P+LII
Sbjct: 140 GLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLII 199
Query: 631 AGMSCYSRCLDYKRFREIADANGAYLMADMAHVSGLVAAGVIPSPFEYC 777
AG SCYSR L+Y R R+IAD NGAYLMADMAH+SGLVAAGV+PSPFE+C
Sbjct: 200 AGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHC 248
>L23928-2|AAA36018.1| 444|Homo sapiens serine
hydroxymethyltransferase protein.
Length = 444
Score = 359 bits (882), Expect = 8e-99
Identities = 165/229 (72%), Positives = 193/229 (84%)
Frame = +1
Query: 91 KLLNSNLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPN 270
K+L L ++D E+++II KE +RQR GLE+IASENF S VL+ L SCL+NKYSEG P
Sbjct: 20 KMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPG 79
Query: 271 QRYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIM 450
QRYYGG E+IDE+E L Q R+L+AY+L + WGVNVQPYSGSPANFAVYT +VEPHGRIM
Sbjct: 80 QRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIM 139
Query: 451 GLDLPDGGHLTHGFFTATKKISATSIFFESMPYKVDPKSGLIDYDKLAETAKLFKPRLII 630
GLDLPDGGHLTHGF T KKISATSIFFESMPYKV+P +G I+YD+L E A+LF P+LII
Sbjct: 140 GLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLII 199
Query: 631 AGMSCYSRCLDYKRFREIADANGAYLMADMAHVSGLVAAGVIPSPFEYC 777
AG SCYSR L+Y R R+IAD NGAYLMADMAH+SGLVAAGV+PSPFE+C
Sbjct: 200 AGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHC 248
>L23928-1|AAA36020.1| 483|Homo sapiens serine
hydroxymethyltransferase protein.
Length = 483
Score = 359 bits (882), Expect = 8e-99
Identities = 165/229 (72%), Positives = 193/229 (84%)
Frame = +1
Query: 91 KLLNSNLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPN 270
K+L L ++D E+++II KE +RQR GLE+IASENF S VL+ L SCL+NKYSEG P
Sbjct: 20 KMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPG 79
Query: 271 QRYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIM 450
QRYYGG E+IDE+E L Q R+L+AY+L + WGVNVQPYSGSPANFAVYT +VEPHGRIM
Sbjct: 80 QRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIM 139
Query: 451 GLDLPDGGHLTHGFFTATKKISATSIFFESMPYKVDPKSGLIDYDKLAETAKLFKPRLII 630
GLDLPDGGHLTHGF T KKISATSIFFESMPYKV+P +G I+YD+L E A+LF P+LII
Sbjct: 140 GLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLII 199
Query: 631 AGMSCYSRCLDYKRFREIADANGAYLMADMAHVSGLVAAGVIPSPFEYC 777
AG SCYSR L+Y R R+IAD NGAYLMADMAH+SGLVAAGV+PSPFE+C
Sbjct: 200 AGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHC 248
>L11931-1|AAA63257.1| 483|Homo sapiens serine
hydroxymethyltransferase protein.
Length = 483
Score = 359 bits (882), Expect = 8e-99
Identities = 165/229 (72%), Positives = 193/229 (84%)
Frame = +1
Query: 91 KLLNSNLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPN 270
K+L L ++D E+++II KE +RQR GLE+IASENF S VL+ L SCL+NKYSEG P
Sbjct: 20 KMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPG 79
Query: 271 QRYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIM 450
QRYYGG E+IDE+E L Q R+L+AY+L + WGVNVQPYSGSPANFAVYT +VEPHGRIM
Sbjct: 80 QRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIM 139
Query: 451 GLDLPDGGHLTHGFFTATKKISATSIFFESMPYKVDPKSGLIDYDKLAETAKLFKPRLII 630
GLDLPDGGHLTHGF T KKISATSIFFESMPYKV+P +G I+YD+L E A+LF P+LII
Sbjct: 140 GLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLII 199
Query: 631 AGMSCYSRCLDYKRFREIADANGAYLMADMAHVSGLVAAGVIPSPFEYC 777
AG SCYSR L+Y R R+IAD NGAYLMADMAH+SGLVAAGV+PSPFE+C
Sbjct: 200 AGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHC 248
>BC038598-1|AAH38598.1| 483|Homo sapiens serine
hydroxymethyltransferase 1 (soluble) protein.
Length = 483
Score = 359 bits (882), Expect = 8e-99
Identities = 165/229 (72%), Positives = 193/229 (84%)
Frame = +1
Query: 91 KLLNSNLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPN 270
K+L L ++D E+++II KE +RQR GLE+IASENF S VL+ L SCL+NKYSEG P
Sbjct: 20 KMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPG 79
Query: 271 QRYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIM 450
QRYYGG E+IDE+E L Q R+L+AY+L + WGVNVQPYSGSPANFAVYT +VEPHGRIM
Sbjct: 80 QRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIM 139
Query: 451 GLDLPDGGHLTHGFFTATKKISATSIFFESMPYKVDPKSGLIDYDKLAETAKLFKPRLII 630
GLDLPDGGHLTHGF T KKISATSIFFESMPYKV+P +G I+YD+L E A+LF P+LII
Sbjct: 140 GLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLII 199
Query: 631 AGMSCYSRCLDYKRFREIADANGAYLMADMAHVSGLVAAGVIPSPFEYC 777
AG SCYSR L+Y R R+IAD NGAYLMADMAH+SGLVAAGV+PSPFE+C
Sbjct: 200 AGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHC 248
>BC022874-1|AAH22874.1| 444|Homo sapiens serine
hydroxymethyltransferase 1 (soluble) protein.
Length = 444
Score = 359 bits (882), Expect = 8e-99
Identities = 165/229 (72%), Positives = 193/229 (84%)
Frame = +1
Query: 91 KLLNSNLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPN 270
K+L L ++D E+++II KE +RQR GLE+IASENF S VL+ L SCL+NKYSEG P
Sbjct: 20 KMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPG 79
Query: 271 QRYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIM 450
QRYYGG E+IDE+E L Q R+L+AY+L + WGVNVQPYSGSPANFAVYT +VEPHGRIM
Sbjct: 80 QRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIM 139
Query: 451 GLDLPDGGHLTHGFFTATKKISATSIFFESMPYKVDPKSGLIDYDKLAETAKLFKPRLII 630
GLDLPDGGHLTHGF T KKISATSIFFESMPYKV+P +G I+YD+L E A+LF P+LII
Sbjct: 140 GLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLII 199
Query: 631 AGMSCYSRCLDYKRFREIADANGAYLMADMAHVSGLVAAGVIPSPFEYC 777
AG SCYSR L+Y R R+IAD NGAYLMADMAH+SGLVAAGV+PSPFE+C
Sbjct: 200 AGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHC 248
>BC007979-1|AAH07979.1| 483|Homo sapiens serine
hydroxymethyltransferase 1 (soluble) protein.
Length = 483
Score = 359 bits (882), Expect = 8e-99
Identities = 165/229 (72%), Positives = 193/229 (84%)
Frame = +1
Query: 91 KLLNSNLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPN 270
K+L L ++D E+++II KE +RQR GLE+IASENF S VL+ L SCL+NKYSEG P
Sbjct: 20 KMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPG 79
Query: 271 QRYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIM 450
QRYYGG E+IDE+E L Q R+L+AY+L + WGVNVQPYSGSPANFAVYT +VEPHGRIM
Sbjct: 80 QRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIM 139
Query: 451 GLDLPDGGHLTHGFFTATKKISATSIFFESMPYKVDPKSGLIDYDKLAETAKLFKPRLII 630
GLDLPDGGHLTHGF T KKISATSIFFESMPYKV+P +G I+YD+L E A+LF P+LII
Sbjct: 140 GLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLII 199
Query: 631 AGMSCYSRCLDYKRFREIADANGAYLMADMAHVSGLVAAGVIPSPFEYC 777
AG SCYSR L+Y R R+IAD NGAYLMADMAH+SGLVAAGV+PSPFE+C
Sbjct: 200 AGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHC 248
>AK223552-1|BAD97272.1| 483|Homo sapiens serine
hydroxymethyltransferase 1 (soluble) isoform 1 variant
protein.
Length = 483
Score = 359 bits (882), Expect = 8e-99
Identities = 165/229 (72%), Positives = 193/229 (84%)
Frame = +1
Query: 91 KLLNSNLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPN 270
K+L L ++D E+++II KE +RQR GLE+IASENF S VL+ L SCL+NKYSEG P
Sbjct: 20 KMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPG 79
Query: 271 QRYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIM 450
QRYYGG E+IDE+E L Q R+L+AY+L + WGVNVQPYSGSPANFAVYT +VEPHGRIM
Sbjct: 80 QRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIM 139
Query: 451 GLDLPDGGHLTHGFFTATKKISATSIFFESMPYKVDPKSGLIDYDKLAETAKLFKPRLII 630
GLDLPDGGHLTHGF T KKISATSIFFESMPYKV+P +G I+YD+L E A+LF P+LII
Sbjct: 140 GLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLII 199
Query: 631 AGMSCYSRCLDYKRFREIADANGAYLMADMAHVSGLVAAGVIPSPFEYC 777
AG SCYSR L+Y R R+IAD NGAYLMADMAH+SGLVAAGV+PSPFE+C
Sbjct: 200 AGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHC 248
>U23143-1|AAA64572.1| 483|Homo sapiens mitochondrial serine
hydroxymethyltransferase protein.
Length = 483
Score = 328 bits (806), Expect = 1e-89
Identities = 148/225 (65%), Positives = 187/225 (83%)
Frame = +1
Query: 106 NLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPNQRYYG 285
+L ++DPE+++++ +EKDRQ GLE+IASENF S L+ L SCL+NKYSEG P +RYYG
Sbjct: 27 SLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYG 86
Query: 286 GNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIMGLDLP 465
G E +DEIE+L Q R+LEA+ L +WGVNVQPYSGSPAN AVYT +++PH RIMGLDLP
Sbjct: 87 GAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLP 146
Query: 466 DGGHLTHGFFTATKKISATSIFFESMPYKVDPKSGLIDYDKLAETAKLFKPRLIIAGMSC 645
DGGHLTHG+ + K+ISATSIFFESMPYK++PK+GLIDY++LA TA+LF+PRLIIAG S
Sbjct: 147 DGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSA 206
Query: 646 YSRCLDYKRFREIADANGAYLMADMAHVSGLVAAGVIPSPFEYCD 780
Y+R +DY R RE+ D A+L+ADMAH+SGLVAA VIPSPF++ D
Sbjct: 207 YARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHAD 251
>L11932-1|AAA63258.1| 474|Homo sapiens serine
hydroxymethyltransferase protein.
Length = 474
Score = 328 bits (806), Expect = 1e-89
Identities = 148/225 (65%), Positives = 187/225 (83%)
Frame = +1
Query: 106 NLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPNQRYYG 285
+L ++DPE+++++ +EKDRQ GLE+IASENF S L+ L SCL+NKYSEG P +RYYG
Sbjct: 18 SLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYG 77
Query: 286 GNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIMGLDLP 465
G E +DEIE+L Q R+LEA+ L +WGVNVQPYSGSPAN AVYT +++PH RIMGLDLP
Sbjct: 78 GAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLP 137
Query: 466 DGGHLTHGFFTATKKISATSIFFESMPYKVDPKSGLIDYDKLAETAKLFKPRLIIAGMSC 645
DGGHLTHG+ + K+ISATSIFFESMPYK++PK+GLIDY++LA TA+LF+PRLIIAG S
Sbjct: 138 DGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSA 197
Query: 646 YSRCLDYKRFREIADANGAYLMADMAHVSGLVAAGVIPSPFEYCD 780
Y+R +DY R RE+ D A+L+ADMAH+SGLVAA VIPSPF++ D
Sbjct: 198 YARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHAD 242
>BT006866-1|AAP35512.1| 504|Homo sapiens serine
hydroxymethyltransferase 2 (mitochondrial) protein.
Length = 504
Score = 328 bits (806), Expect = 1e-89
Identities = 148/225 (65%), Positives = 187/225 (83%)
Frame = +1
Query: 106 NLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPNQRYYG 285
+L ++DPE+++++ +EKDRQ GLE+IASENF S L+ L SCL+NKYSEG P +RYYG
Sbjct: 48 SLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYG 107
Query: 286 GNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIMGLDLP 465
G E +DEIE+L Q R+LEA+ L +WGVNVQPYSGSPAN AVYT +++PH RIMGLDLP
Sbjct: 108 GAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLP 167
Query: 466 DGGHLTHGFFTATKKISATSIFFESMPYKVDPKSGLIDYDKLAETAKLFKPRLIIAGMSC 645
DGGHLTHG+ + K+ISATSIFFESMPYK++PK+GLIDY++LA TA+LF+PRLIIAG S
Sbjct: 168 DGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSA 227
Query: 646 YSRCLDYKRFREIADANGAYLMADMAHVSGLVAAGVIPSPFEYCD 780
Y+R +DY R RE+ D A+L+ADMAH+SGLVAA VIPSPF++ D
Sbjct: 228 YARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHAD 272
>BC044211-1|AAH44211.1| 504|Homo sapiens serine
hydroxymethyltransferase 2 (mitochondrial) protein.
Length = 504
Score = 328 bits (806), Expect = 1e-89
Identities = 148/225 (65%), Positives = 187/225 (83%)
Frame = +1
Query: 106 NLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPNQRYYG 285
+L ++DPE+++++ +EKDRQ GLE+IASENF S L+ L SCL+NKYSEG P +RYYG
Sbjct: 48 SLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYG 107
Query: 286 GNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIMGLDLP 465
G E +DEIE+L Q R+LEA+ L +WGVNVQPYSGSPAN AVYT +++PH RIMGLDLP
Sbjct: 108 GAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLP 167
Query: 466 DGGHLTHGFFTATKKISATSIFFESMPYKVDPKSGLIDYDKLAETAKLFKPRLIIAGMSC 645
DGGHLTHG+ + K+ISATSIFFESMPYK++PK+GLIDY++LA TA+LF+PRLIIAG S
Sbjct: 168 DGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSA 227
Query: 646 YSRCLDYKRFREIADANGAYLMADMAHVSGLVAAGVIPSPFEYCD 780
Y+R +DY R RE+ D A+L+ADMAH+SGLVAA VIPSPF++ D
Sbjct: 228 YARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHAD 272
>BC013677-1|AAH13677.1| 504|Homo sapiens serine
hydroxymethyltransferase 2 (mitochondrial) protein.
Length = 504
Score = 328 bits (806), Expect = 1e-89
Identities = 148/225 (65%), Positives = 187/225 (83%)
Frame = +1
Query: 106 NLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPNQRYYG 285
+L ++DPE+++++ +EKDRQ GLE+IASENF S L+ L SCL+NKYSEG P +RYYG
Sbjct: 48 SLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYG 107
Query: 286 GNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIMGLDLP 465
G E +DEIE+L Q R+LEA+ L +WGVNVQPYSGSPAN AVYT +++PH RIMGLDLP
Sbjct: 108 GAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLP 167
Query: 466 DGGHLTHGFFTATKKISATSIFFESMPYKVDPKSGLIDYDKLAETAKLFKPRLIIAGMSC 645
DGGHLTHG+ + K+ISATSIFFESMPYK++PK+GLIDY++LA TA+LF+PRLIIAG S
Sbjct: 168 DGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSA 227
Query: 646 YSRCLDYKRFREIADANGAYLMADMAHVSGLVAAGVIPSPFEYCD 780
Y+R +DY R RE+ D A+L+ADMAH+SGLVAA VIPSPF++ D
Sbjct: 228 YARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHAD 272
>BC011911-1|AAH11911.1| 504|Homo sapiens serine
hydroxymethyltransferase 2 (mitochondrial) protein.
Length = 504
Score = 328 bits (806), Expect = 1e-89
Identities = 148/225 (65%), Positives = 187/225 (83%)
Frame = +1
Query: 106 NLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPNQRYYG 285
+L ++DPE+++++ +EKDRQ GLE+IASENF S L+ L SCL+NKYSEG P +RYYG
Sbjct: 48 SLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYG 107
Query: 286 GNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIMGLDLP 465
G E +DEIE+L Q R+LEA+ L +WGVNVQPYSGSPAN AVYT +++PH RIMGLDLP
Sbjct: 108 GAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLP 167
Query: 466 DGGHLTHGFFTATKKISATSIFFESMPYKVDPKSGLIDYDKLAETAKLFKPRLIIAGMSC 645
DGGHLTHG+ + K+ISATSIFFESMPYK++PK+GLIDY++LA TA+LF+PRLIIAG S
Sbjct: 168 DGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSA 227
Query: 646 YSRCLDYKRFREIADANGAYLMADMAHVSGLVAAGVIPSPFEYCD 780
Y+R +DY R RE+ D A+L+ADMAH+SGLVAA VIPSPF++ D
Sbjct: 228 YARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHAD 272
>AK223555-1|BAD97275.1| 504|Homo sapiens serine
hydroxymethyltransferase 2 (mitochondrial) variant
protein.
Length = 504
Score = 328 bits (806), Expect = 1e-89
Identities = 148/225 (65%), Positives = 187/225 (83%)
Frame = +1
Query: 106 NLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPNQRYYG 285
+L ++DPE+++++ +EKDRQ GLE+IASENF S L+ L SCL+NKYSEG P +RYYG
Sbjct: 48 SLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYG 107
Query: 286 GNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIMGLDLP 465
G E +DEIE+L Q R+LEA+ L +WGVNVQPYSGSPAN AVYT +++PH RIMGLDLP
Sbjct: 108 GAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLP 167
Query: 466 DGGHLTHGFFTATKKISATSIFFESMPYKVDPKSGLIDYDKLAETAKLFKPRLIIAGMSC 645
DGGHLTHG+ + K+ISATSIFFESMPYK++PK+GLIDY++LA TA+LF+PRLIIAG S
Sbjct: 168 DGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSA 227
Query: 646 YSRCLDYKRFREIADANGAYLMADMAHVSGLVAAGVIPSPFEYCD 780
Y+R +DY R RE+ D A+L+ADMAH+SGLVAA VIPSPF++ D
Sbjct: 228 YARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHAD 272
>BC032584-1|AAH32584.1| 494|Homo sapiens SHMT2 protein protein.
Length = 494
Score = 299 bits (735), Expect = 5e-81
Identities = 141/225 (62%), Positives = 177/225 (78%)
Frame = +1
Query: 106 NLWEADPELFDIIVKEKDRQRAGLEMIASENFTSVPVLQCLSSCLHNKYSEGMPNQRYYG 285
+L ++DPE+++++ +EKDRQ GLE+IASENF S L+ L SCL+NKYSEG P +RYYG
Sbjct: 48 SLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYG 107
Query: 286 GNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIMGLDLP 465
G E +DEIE+L Q R+LEA+ L +WGVNVQPYSGSPAN AVYT +++PH RIMGLDLP
Sbjct: 108 GAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLP 167
Query: 466 DGGHLTHGFFTATKKISATSIFFESMPYKVDPKSGLIDYDKLAETAKLFKPRLIIAGMSC 645
DGGHLTHG+ + K+ISATSIFFESMPYK++ LA TA+LF+PRLIIAG S
Sbjct: 168 DGGHLTHGYMSDVKRISATSIFFESMPYKLN----------LALTARLFRPRLIIAGTSA 217
Query: 646 YSRCLDYKRFREIADANGAYLMADMAHVSGLVAAGVIPSPFEYCD 780
Y+R +DY R RE+ D A+L+ADMAH+SGLVAA VIPSPF++ D
Sbjct: 218 YARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHAD 262
>BC091501-1|AAH91501.1| 480|Homo sapiens SHMT2 protein protein.
Length = 480
Score = 263 bits (644), Expect = 6e-70
Identities = 118/170 (69%), Positives = 144/170 (84%)
Frame = +1
Query: 271 QRYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQPYSGSPANFAVYTGIVEPHGRIM 450
QRYYGG E +DEIE+L Q R+LEA+ L +WGVNVQPYSGSPAN AVYT +++PH RIM
Sbjct: 79 QRYYGGAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIM 138
Query: 451 GLDLPDGGHLTHGFFTATKKISATSIFFESMPYKVDPKSGLIDYDKLAETAKLFKPRLII 630
GLDLPDGGHLTHG+ + K+ISATSIFFESMPYK++PK+GLIDY++LA TA+LF+PRLII
Sbjct: 139 GLDLPDGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLII 198
Query: 631 AGMSCYSRCLDYKRFREIADANGAYLMADMAHVSGLVAAGVIPSPFEYCD 780
AG S Y+R +DY R RE+ D A+L+ADMAH+SGLVAA VIPSPF++ D
Sbjct: 199 AGTSAYARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHAD 248
>Y14486-1|CAB54839.1| 310|Homo sapiens cytosolic serine
hydroxymethyltransferase protein.
Length = 310
Score = 121 bits (292), Expect = 3e-27
Identities = 54/75 (72%), Positives = 65/75 (86%)
Frame = +1
Query: 553 VDPKSGLIDYDKLAETAKLFKPRLIIAGMSCYSRCLDYKRFREIADANGAYLMADMAHVS 732
V+P +G I+YD+L E A+LF P+LIIAG SCYSR L+Y R R+IAD NGAYLMADMAH+S
Sbjct: 1 VNPDTGYINYDQLEENARLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHIS 60
Query: 733 GLVAAGVIPSPFEYC 777
GLVAAGV+PSPFE+C
Sbjct: 61 GLVAAGVVPSPFEHC 75
>Y14488-1|CAB54841.1| 129|Homo sapiens 14 kDa protein protein.
Length = 129
Score = 55.2 bits (127), Expect = 3e-07
Identities = 22/37 (59%), Positives = 29/37 (78%)
Frame = +1
Query: 274 RYYGGNEYIDEIEILAQNRSLEAYRLKSEEWGVNVQP 384
RYYGG E+IDE+E L Q R+L+AY+L + WGV+V P
Sbjct: 65 RYYGGTEFIDELETLCQKRALQAYKLDPQCWGVDVHP 101
>AK055053-1|BAB70847.1| 135|Homo sapiens protein.
Length = 135
Score = 39.5 bits (88), Expect = 0.013
Identities = 16/30 (53%), Positives = 26/30 (86%)
Frame = +1
Query: 106 NLWEADPELFDIIVKEKDRQRAGLEMIASE 195
+L ++DPE+++++ +EKDRQ GLE+IASE
Sbjct: 48 SLSDSDPEMWELLQREKDRQCRGLELIASE 77
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 116,254,560
Number of Sequences: 237096
Number of extensions: 2481428
Number of successful extensions: 5023
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 4760
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5022
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9534535578
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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