Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= bmnc18h05
(600 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AB209534-1|BAD92771.1| 576|Homo sapiens tumor rejection antigen... 163 3e-40
X15187-1|CAA33261.1| 803|Homo sapiens precursor polypeptide (AA... 162 1e-39
BC066656-1|AAH66656.1| 803|Homo sapiens heat shock protein 90kD... 162 1e-39
BC009195-1|AAH09195.1| 315|Homo sapiens HSP90B1 protein protein. 162 1e-39
AJ890084-1|CAI64497.1| 802|Homo sapiens tumor rejection antigen... 162 1e-39
AY040226-1|AAK74072.1| 782|Homo sapiens heat shock protein gp96... 159 9e-39
M16660-1|AAA36025.1| 724|Homo sapiens protein ( Human 90-kDa he... 85 2e-16
J04988-1|AAA36026.1| 724|Homo sapiens protein ( Human 90 kD hea... 85 2e-16
DQ314872-1|ABC40731.1| 724|Homo sapiens heat shock 90kDa protei... 85 2e-16
BC068474-1|AAH68474.1| 724|Homo sapiens heat shock protein 90kD... 85 2e-16
BC016753-1|AAH16753.1| 724|Homo sapiens heat shock protein 90kD... 85 2e-16
BC014485-1|AAH14485.1| 724|Homo sapiens heat shock protein 90kD... 85 2e-16
BC012807-1|AAH12807.1| 724|Homo sapiens heat shock protein 90kD... 85 2e-16
BC007327-1|AAH07327.1| 351|Homo sapiens HSP90AB1 protein protein. 85 2e-16
BC004928-1|AAH04928.1| 724|Homo sapiens heat shock protein 90kD... 85 2e-16
AY359878-1|AAQ63401.1| 724|Homo sapiens heat shock 90kDa protei... 85 2e-16
AL139392-3|CAI20095.1| 724|Homo sapiens heat shock protein 90kD... 85 2e-16
AL136543-1|CAB66478.1| 737|Homo sapiens hypothetical protein pr... 85 2e-16
DQ314871-1|ABC40730.1| 854|Homo sapiens heat shock 90kDa protei... 82 2e-15
X07270-1|CAA30255.1| 312|Homo sapiens protein ( Human mRNA for ... 81 2e-15
M30626-1|AAA36023.1| 312|Homo sapiens heat shock protein 86 pro... 81 2e-15
M27024-1|AAA63194.1| 732|Homo sapiens heat shock protein protein. 81 2e-15
BC121062-1|AAI21063.1| 732|Homo sapiens heat shock protein 90kD... 81 2e-15
BC108695-1|AAI08696.1| 585|Homo sapiens HSP90AA1 protein protein. 81 2e-15
AJ890083-1|CAI64496.1| 732|Homo sapiens Heat shock protein HSP ... 81 2e-15
AJ890082-1|CAI64495.1| 854|Homo sapiens Heat shock protein HSP ... 81 3e-15
X15183-1|CAA33259.1| 732|Homo sapiens protein ( Human mRNA for ... 80 5e-15
AY956764-1|AAX38251.1| 597|Homo sapiens heat shock protein 90Bc... 80 5e-15
AL139392-2|CAI20094.1| 168|Homo sapiens heat shock protein 90kD... 79 1e-14
M30627-1|AAA36024.1| 312|Homo sapiens heat shock protein 86 pro... 77 6e-14
AY956763-1|AAX38250.1| 422|Homo sapiens heat shock protein 90Bb... 76 1e-13
AY956765-1|AAX38252.1| 505|Homo sapiens heat shock protein 90Bd... 69 1e-11
U12595-1|AAA87704.1| 661|Homo sapiens tumor necrosis factor typ... 61 3e-09
BC023585-1|AAH23585.1| 704|Homo sapiens TNF receptor-associated... 61 3e-09
BC018950-1|AAH18950.1| 704|Homo sapiens TNF receptor-associated... 61 3e-09
BC001455-1|AAH01455.2| 699|Homo sapiens TRAP1 protein protein. 61 3e-09
AK223205-1|BAD96925.1| 704|Homo sapiens TNF receptor-associated... 61 3e-09
AK223076-1|BAD96796.1| 704|Homo sapiens TNF receptor-associated... 61 3e-09
AK223049-1|BAD96769.1| 704|Homo sapiens TNF receptor-associated... 61 3e-09
AF154108-1|AAF15314.1| 704|Homo sapiens tumor necrosis factor t... 61 3e-09
AF043254-1|AAC02679.1| 649|Homo sapiens heat shock protein 75 p... 61 3e-09
AC005203-2|AAC24722.1| 616|Homo sapiens TRAP1 protein. 61 3e-09
AB209805-1|BAD93042.1| 703|Homo sapiens TNF receptor-associated... 61 3e-09
AK093344-1|BAC04139.1| 579|Homo sapiens protein ( Homo sapiens ... 59 1e-08
D17804-1|BAA22050.1| 130|Homo sapiens heat shock protein beta p... 35 0.25
S70561-1|AAD14062.1| 68|Homo sapiens 90-kda heat shock protein... 33 0.77
BC086869-1|AAH86869.1| 954|Homo sapiens FLJ25770 protein protein. 30 7.1
AK098600-1|BAC05347.1| 424|Homo sapiens protein ( Homo sapiens ... 30 7.1
>AB209534-1|BAD92771.1| 576|Homo sapiens tumor rejection antigen
(gp96) 1 variant protein.
Length = 576
Score = 163 bits (397), Expect = 3e-40
Identities = 82/149 (55%), Positives = 105/149 (70%)
Frame = +2
Query: 149 AMKHIWLFGLGVLLLSGWSXXXXXXXXXXXXXXXXXLGSSREGSRTDAEAVLREEEAISP 328
AM+ +W+ GL +LL+ + LG SREGSRTD E V REEEAI
Sbjct: 26 AMRALWVLGLCCVLLT-FGSVRADDEVDVDGTVEEDLGKSREGSRTDDEVVQREEEAIQL 84
Query: 329 DALSVAQMKELRDRAQNYTFQTEVNRMMKLIINSLYRNKEIFLRELISNGSDALDKIRLM 508
D L+ +Q++ELR++++ + FQ EVNRMMKLIINSLY+NKEIFLRELISN SDALDKIRL+
Sbjct: 85 DGLNASQIRELREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLI 144
Query: 509 SLTDRGVLEANPELSIRIKAEPDKRLLHI 595
SLTD L N EL+++IK + +K LLH+
Sbjct: 145 SLTDENALSGNEELTVKIKCDKEKNLLHV 173
>X15187-1|CAA33261.1| 803|Homo sapiens precursor polypeptide (AA-21
to 782) protein.
Length = 803
Score = 162 bits (393), Expect = 1e-39
Identities = 81/148 (54%), Positives = 104/148 (70%)
Frame = +2
Query: 152 MKHIWLFGLGVLLLSGWSXXXXXXXXXXXXXXXXXLGSSREGSRTDAEAVLREEEAISPD 331
M+ +W+ GL +LL+ + LG SREGSRTD E V REEEAI D
Sbjct: 1 MRALWVLGLCCVLLT-FGSVRADDEVDVDGTVEEDLGKSREGSRTDDEVVQREEEAIQLD 59
Query: 332 ALSVAQMKELRDRAQNYTFQTEVNRMMKLIINSLYRNKEIFLRELISNGSDALDKIRLMS 511
L+ +Q++ELR++++ + FQ EVNRMMKLIINSLY+NKEIFLRELISN SDALDKIRL+S
Sbjct: 60 GLNASQIRELREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLIS 119
Query: 512 LTDRGVLEANPELSIRIKAEPDKRLLHI 595
LTD L N EL+++IK + +K LLH+
Sbjct: 120 LTDENALSGNEELTVKIKCDKEKNLLHV 147
>BC066656-1|AAH66656.1| 803|Homo sapiens heat shock protein 90kDa
beta (Grp94), member 1 protein.
Length = 803
Score = 162 bits (393), Expect = 1e-39
Identities = 81/148 (54%), Positives = 104/148 (70%)
Frame = +2
Query: 152 MKHIWLFGLGVLLLSGWSXXXXXXXXXXXXXXXXXLGSSREGSRTDAEAVLREEEAISPD 331
M+ +W+ GL +LL+ + LG SREGSRTD E V REEEAI D
Sbjct: 1 MRALWVLGLCCVLLT-FGSVRADDEVDVDGTVEEDLGKSREGSRTDDEVVQREEEAIQLD 59
Query: 332 ALSVAQMKELRDRAQNYTFQTEVNRMMKLIINSLYRNKEIFLRELISNGSDALDKIRLMS 511
L+ +Q++ELR++++ + FQ EVNRMMKLIINSLY+NKEIFLRELISN SDALDKIRL+S
Sbjct: 60 GLNASQIRELREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLIS 119
Query: 512 LTDRGVLEANPELSIRIKAEPDKRLLHI 595
LTD L N EL+++IK + +K LLH+
Sbjct: 120 LTDENALSGNEELTVKIKCDKEKNLLHV 147
>BC009195-1|AAH09195.1| 315|Homo sapiens HSP90B1 protein protein.
Length = 315
Score = 162 bits (393), Expect = 1e-39
Identities = 81/148 (54%), Positives = 104/148 (70%)
Frame = +2
Query: 152 MKHIWLFGLGVLLLSGWSXXXXXXXXXXXXXXXXXLGSSREGSRTDAEAVLREEEAISPD 331
M+ +W+ GL +LL+ + LG SREGSRTD E V REEEAI D
Sbjct: 1 MRALWVLGLCCVLLT-FGSVRADDEVDVDGTVEEDLGKSREGSRTDDEVVQREEEAIQLD 59
Query: 332 ALSVAQMKELRDRAQNYTFQTEVNRMMKLIINSLYRNKEIFLRELISNGSDALDKIRLMS 511
L+ +Q++ELR++++ + FQ EVNRMMKLIINSLY+NKEIFLRELISN SDALDKIRL+S
Sbjct: 60 GLNASQIRELREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLIS 119
Query: 512 LTDRGVLEANPELSIRIKAEPDKRLLHI 595
LTD L N EL+++IK + +K LLH+
Sbjct: 120 LTDENALSGNEELTVKIKCDKEKNLLHV 147
>AJ890084-1|CAI64497.1| 802|Homo sapiens tumor rejection antigen
(gp96) 1 protein.
Length = 802
Score = 162 bits (393), Expect = 1e-39
Identities = 81/148 (54%), Positives = 104/148 (70%)
Frame = +2
Query: 152 MKHIWLFGLGVLLLSGWSXXXXXXXXXXXXXXXXXLGSSREGSRTDAEAVLREEEAISPD 331
M+ +W+ GL +LL+ + LG SREGSRTD E V REEEAI D
Sbjct: 1 MRALWVLGLCCVLLT-FGSVRADDEVDVDGTVEEDLGKSREGSRTDDEVVQREEEAIQLD 59
Query: 332 ALSVAQMKELRDRAQNYTFQTEVNRMMKLIINSLYRNKEIFLRELISNGSDALDKIRLMS 511
L+ +Q++ELR++++ + FQ EVNRMMKLIINSLY+NKEIFLRELISN SDALDKIRL+S
Sbjct: 60 GLNASQIRELREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLIS 119
Query: 512 LTDRGVLEANPELSIRIKAEPDKRLLHI 595
LTD L N EL+++IK + +K LLH+
Sbjct: 120 LTDENALSGNEELTVKIKCDKEKNLLHV 147
>AY040226-1|AAK74072.1| 782|Homo sapiens heat shock protein gp96
precursor protein.
Length = 782
Score = 159 bits (385), Expect = 9e-39
Identities = 75/113 (66%), Positives = 92/113 (81%)
Frame = +2
Query: 257 LGSSREGSRTDAEAVLREEEAISPDALSVAQMKELRDRAQNYTFQTEVNRMMKLIINSLY 436
LG SREGSRTD E V REEEAI D L+ +Q++ELR++++ + FQ EVNRMMKLIINSLY
Sbjct: 14 LGKSREGSRTDDEVVQREEEAIQLDGLNASQIRELREKSEKFAFQAEVNRMMKLIINSLY 73
Query: 437 RNKEIFLRELISNGSDALDKIRLMSLTDRGVLEANPELSIRIKAEPDKRLLHI 595
+NKEIFLRELISN SDALDKIRL+SLTD L N EL+++IK + +K LLH+
Sbjct: 74 KNKEIFLRELISNASDALDKIRLISLTDENALSGNEELTVKIKCDKEKNLLHV 126
>M16660-1|AAA36025.1| 724|Homo sapiens protein ( Human 90-kDa
heat-shock protein gene, cDNA, complete cds. ).
Length = 724
Score = 85.0 bits (201), Expect = 2e-16
Identities = 41/78 (52%), Positives = 53/78 (67%)
Frame = +2
Query: 365 DRAQNYTFQTEVNRMMKLIINSLYRNKEIFLRELISNGSDALDKIRLMSLTDRGVLEANP 544
+ + + FQ E+ ++M LIIN+ Y NKEIFLRELISN SDALDKIR SLTD L++
Sbjct: 10 EEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGK 69
Query: 545 ELSIRIKAEPDKRLLHII 598
EL I I P +R L ++
Sbjct: 70 ELKIDIIPNPQERTLTLV 87
>J04988-1|AAA36026.1| 724|Homo sapiens protein ( Human 90 kD heat
shock protein gene, complete cds. ).
Length = 724
Score = 85.0 bits (201), Expect = 2e-16
Identities = 41/78 (52%), Positives = 53/78 (67%)
Frame = +2
Query: 365 DRAQNYTFQTEVNRMMKLIINSLYRNKEIFLRELISNGSDALDKIRLMSLTDRGVLEANP 544
+ + + FQ E+ ++M LIIN+ Y NKEIFLRELISN SDALDKIR SLTD L++
Sbjct: 10 EEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGK 69
Query: 545 ELSIRIKAEPDKRLLHII 598
EL I I P +R L ++
Sbjct: 70 ELKIDIIPNPQERTLTLV 87
>DQ314872-1|ABC40731.1| 724|Homo sapiens heat shock 90kDa protein
1, beta protein.
Length = 724
Score = 85.0 bits (201), Expect = 2e-16
Identities = 41/78 (52%), Positives = 53/78 (67%)
Frame = +2
Query: 365 DRAQNYTFQTEVNRMMKLIINSLYRNKEIFLRELISNGSDALDKIRLMSLTDRGVLEANP 544
+ + + FQ E+ ++M LIIN+ Y NKEIFLRELISN SDALDKIR SLTD L++
Sbjct: 10 EEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGK 69
Query: 545 ELSIRIKAEPDKRLLHII 598
EL I I P +R L ++
Sbjct: 70 ELKIDIIPNPQERTLTLV 87
>BC068474-1|AAH68474.1| 724|Homo sapiens heat shock protein 90kDa
alpha (cytosolic), class B member 1 protein.
Length = 724
Score = 85.0 bits (201), Expect = 2e-16
Identities = 41/78 (52%), Positives = 53/78 (67%)
Frame = +2
Query: 365 DRAQNYTFQTEVNRMMKLIINSLYRNKEIFLRELISNGSDALDKIRLMSLTDRGVLEANP 544
+ + + FQ E+ ++M LIIN+ Y NKEIFLRELISN SDALDKIR SLTD L++
Sbjct: 10 EEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGK 69
Query: 545 ELSIRIKAEPDKRLLHII 598
EL I I P +R L ++
Sbjct: 70 ELKIDIIPNPQERTLTLV 87
>BC016753-1|AAH16753.1| 724|Homo sapiens heat shock protein 90kDa
alpha (cytosolic), class B member 1 protein.
Length = 724
Score = 85.0 bits (201), Expect = 2e-16
Identities = 41/78 (52%), Positives = 53/78 (67%)
Frame = +2
Query: 365 DRAQNYTFQTEVNRMMKLIINSLYRNKEIFLRELISNGSDALDKIRLMSLTDRGVLEANP 544
+ + + FQ E+ ++M LIIN+ Y NKEIFLRELISN SDALDKIR SLTD L++
Sbjct: 10 EEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGK 69
Query: 545 ELSIRIKAEPDKRLLHII 598
EL I I P +R L ++
Sbjct: 70 ELKIDIIPNPQERTLTLV 87
>BC014485-1|AAH14485.1| 724|Homo sapiens heat shock protein 90kDa
alpha (cytosolic), class B member 1 protein.
Length = 724
Score = 85.0 bits (201), Expect = 2e-16
Identities = 41/78 (52%), Positives = 53/78 (67%)
Frame = +2
Query: 365 DRAQNYTFQTEVNRMMKLIINSLYRNKEIFLRELISNGSDALDKIRLMSLTDRGVLEANP 544
+ + + FQ E+ ++M LIIN+ Y NKEIFLRELISN SDALDKIR SLTD L++
Sbjct: 10 EEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGK 69
Query: 545 ELSIRIKAEPDKRLLHII 598
EL I I P +R L ++
Sbjct: 70 ELKIDIIPNPQERTLTLV 87
>BC012807-1|AAH12807.1| 724|Homo sapiens heat shock protein 90kDa
alpha (cytosolic), class B member 1 protein.
Length = 724
Score = 85.0 bits (201), Expect = 2e-16
Identities = 41/78 (52%), Positives = 53/78 (67%)
Frame = +2
Query: 365 DRAQNYTFQTEVNRMMKLIINSLYRNKEIFLRELISNGSDALDKIRLMSLTDRGVLEANP 544
+ + + FQ E+ ++M LIIN+ Y NKEIFLRELISN SDALDKIR SLTD L++
Sbjct: 10 EEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGK 69
Query: 545 ELSIRIKAEPDKRLLHII 598
EL I I P +R L ++
Sbjct: 70 ELKIDIIPNPQERTLTLV 87
>BC007327-1|AAH07327.1| 351|Homo sapiens HSP90AB1 protein protein.
Length = 351
Score = 85.0 bits (201), Expect = 2e-16
Identities = 41/78 (52%), Positives = 53/78 (67%)
Frame = +2
Query: 365 DRAQNYTFQTEVNRMMKLIINSLYRNKEIFLRELISNGSDALDKIRLMSLTDRGVLEANP 544
+ + + FQ E+ ++M LIIN+ Y NKEIFLRELISN SDALDKIR SLTD L++
Sbjct: 10 EEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGK 69
Query: 545 ELSIRIKAEPDKRLLHII 598
EL I I P +R L ++
Sbjct: 70 ELKIDIIPNPQERTLTLV 87
>BC004928-1|AAH04928.1| 724|Homo sapiens heat shock protein 90kDa
alpha (cytosolic), class B member 1 protein.
Length = 724
Score = 85.0 bits (201), Expect = 2e-16
Identities = 41/78 (52%), Positives = 53/78 (67%)
Frame = +2
Query: 365 DRAQNYTFQTEVNRMMKLIINSLYRNKEIFLRELISNGSDALDKIRLMSLTDRGVLEANP 544
+ + + FQ E+ ++M LIIN+ Y NKEIFLRELISN SDALDKIR SLTD L++
Sbjct: 10 EEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGK 69
Query: 545 ELSIRIKAEPDKRLLHII 598
EL I I P +R L ++
Sbjct: 70 ELKIDIIPNPQERTLTLV 87
>AY359878-1|AAQ63401.1| 724|Homo sapiens heat shock 90kDa protein 1
beta protein.
Length = 724
Score = 85.0 bits (201), Expect = 2e-16
Identities = 41/78 (52%), Positives = 53/78 (67%)
Frame = +2
Query: 365 DRAQNYTFQTEVNRMMKLIINSLYRNKEIFLRELISNGSDALDKIRLMSLTDRGVLEANP 544
+ + + FQ E+ ++M LIIN+ Y NKEIFLRELISN SDALDKIR SLTD L++
Sbjct: 10 EEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGK 69
Query: 545 ELSIRIKAEPDKRLLHII 598
EL I I P +R L ++
Sbjct: 70 ELKIDIIPNPQERTLTLV 87
>AL139392-3|CAI20095.1| 724|Homo sapiens heat shock protein 90kDa
alpha (cytosolic), classn complex) 1B (SPRL1B) pseudog
protein.
Length = 724
Score = 85.0 bits (201), Expect = 2e-16
Identities = 41/78 (52%), Positives = 53/78 (67%)
Frame = +2
Query: 365 DRAQNYTFQTEVNRMMKLIINSLYRNKEIFLRELISNGSDALDKIRLMSLTDRGVLEANP 544
+ + + FQ E+ ++M LIIN+ Y NKEIFLRELISN SDALDKIR SLTD L++
Sbjct: 10 EEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGK 69
Query: 545 ELSIRIKAEPDKRLLHII 598
EL I I P +R L ++
Sbjct: 70 ELKIDIIPNPQERTLTLV 87
>AL136543-1|CAB66478.1| 737|Homo sapiens hypothetical protein
protein.
Length = 737
Score = 85.0 bits (201), Expect = 2e-16
Identities = 41/78 (52%), Positives = 53/78 (67%)
Frame = +2
Query: 365 DRAQNYTFQTEVNRMMKLIINSLYRNKEIFLRELISNGSDALDKIRLMSLTDRGVLEANP 544
+ + + FQ E+ ++M LIIN+ Y NKEIFLRELISN SDALDKIR SLTD L++
Sbjct: 10 EEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGK 69
Query: 545 ELSIRIKAEPDKRLLHII 598
EL I I P +R L ++
Sbjct: 70 ELKIDIIPNPQERTLTLV 87
>DQ314871-1|ABC40730.1| 854|Homo sapiens heat shock 90kDa protein
1, alpha protein.
Length = 854
Score = 81.8 bits (193), Expect = 2e-15
Identities = 41/93 (44%), Positives = 54/93 (58%)
Frame = +2
Query: 320 ISPDALSVAQMKELRDRAQNYTFQTEVNRMMKLIINSLYRNKEIFLRELISNGSDALDKI 499
+ P+ + + + FQ E+ ++M LIIN+ Y NKEIFLRELISN SDALDKI
Sbjct: 122 LMPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKI 181
Query: 500 RLMSLTDRGVLEANPELSIRIKAEPDKRLLHII 598
R SLTD L++ EL I + R L I+
Sbjct: 182 RYESLTDPSKLDSGKELHINLIPNKQDRTLTIV 214
>X07270-1|CAA30255.1| 312|Homo sapiens protein ( Human mRNA for
heat shock protein hsp86. ).
Length = 312
Score = 81.4 bits (192), Expect = 2e-15
Identities = 40/78 (51%), Positives = 51/78 (65%)
Frame = +2
Query: 365 DRAQNYTFQTEVNRMMKLIINSLYRNKEIFLRELISNGSDALDKIRLMSLTDRGVLEANP 544
+ + + FQ E+ ++M LIIN+ Y NKEIFLRELISN SDALDKIR SLTD L++
Sbjct: 15 EEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGK 74
Query: 545 ELSIRIKAEPDKRLLHII 598
EL I + R L I+
Sbjct: 75 ELHINLIPNKQDRTLTIV 92
>M30626-1|AAA36023.1| 312|Homo sapiens heat shock protein 86
protein.
Length = 312
Score = 81.4 bits (192), Expect = 2e-15
Identities = 40/78 (51%), Positives = 51/78 (65%)
Frame = +2
Query: 365 DRAQNYTFQTEVNRMMKLIINSLYRNKEIFLRELISNGSDALDKIRLMSLTDRGVLEANP 544
+ + + FQ E+ ++M LIIN+ Y NKEIFLRELISN SDALDKIR SLTD L++
Sbjct: 15 EEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGK 74
Query: 545 ELSIRIKAEPDKRLLHII 598
EL I + R L I+
Sbjct: 75 ELHINLIPNKQDRTLTIV 92
>M27024-1|AAA63194.1| 732|Homo sapiens heat shock protein protein.
Length = 732
Score = 81.4 bits (192), Expect = 2e-15
Identities = 40/78 (51%), Positives = 51/78 (65%)
Frame = +2
Query: 365 DRAQNYTFQTEVNRMMKLIINSLYRNKEIFLRELISNGSDALDKIRLMSLTDRGVLEANP 544
+ + + FQ E+ ++M LIIN+ Y NKEIFLRELISN SDALDKIR SLTD L++
Sbjct: 15 EEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGK 74
Query: 545 ELSIRIKAEPDKRLLHII 598
EL I + R L I+
Sbjct: 75 ELHINLIPNKQDRTLTIV 92
>BC121062-1|AAI21063.1| 732|Homo sapiens heat shock protein 90kDa
alpha (cytosolic), class A member 1 protein.
Length = 732
Score = 81.4 bits (192), Expect = 2e-15
Identities = 40/78 (51%), Positives = 51/78 (65%)
Frame = +2
Query: 365 DRAQNYTFQTEVNRMMKLIINSLYRNKEIFLRELISNGSDALDKIRLMSLTDRGVLEANP 544
+ + + FQ E+ ++M LIIN+ Y NKEIFLRELISN SDALDKIR SLTD L++
Sbjct: 15 EEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGK 74
Query: 545 ELSIRIKAEPDKRLLHII 598
EL I + R L I+
Sbjct: 75 ELHINLIPNKQDRTLTIV 92
>BC108695-1|AAI08696.1| 585|Homo sapiens HSP90AA1 protein protein.
Length = 585
Score = 81.4 bits (192), Expect = 2e-15
Identities = 40/78 (51%), Positives = 51/78 (65%)
Frame = +2
Query: 365 DRAQNYTFQTEVNRMMKLIINSLYRNKEIFLRELISNGSDALDKIRLMSLTDRGVLEANP 544
+ + + FQ E+ ++M LIIN+ Y NKEIFLRELISN SDALDKIR SLTD L++
Sbjct: 15 EEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGK 74
Query: 545 ELSIRIKAEPDKRLLHII 598
EL I + R L I+
Sbjct: 75 ELHINLIPNKQDRTLTIV 92
>AJ890083-1|CAI64496.1| 732|Homo sapiens Heat shock protein HSP
90-alpha 4 protein.
Length = 732
Score = 81.4 bits (192), Expect = 2e-15
Identities = 40/78 (51%), Positives = 51/78 (65%)
Frame = +2
Query: 365 DRAQNYTFQTEVNRMMKLIINSLYRNKEIFLRELISNGSDALDKIRLMSLTDRGVLEANP 544
+ + + FQ E+ ++M LIIN+ Y NKEIFLRELISN SDALDKIR SLTD L++
Sbjct: 15 EEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGK 74
Query: 545 ELSIRIKAEPDKRLLHII 598
EL I + R L I+
Sbjct: 75 ELHINLIPNKQDRTLTIV 92
>AJ890082-1|CAI64495.1| 854|Homo sapiens Heat shock protein HSP
90-alpha 2 protein.
Length = 854
Score = 81.0 bits (191), Expect = 3e-15
Identities = 41/93 (44%), Positives = 54/93 (58%)
Frame = +2
Query: 320 ISPDALSVAQMKELRDRAQNYTFQTEVNRMMKLIINSLYRNKEIFLRELISNGSDALDKI 499
+ P+ + + + FQ E+ ++M LIIN+ Y NKEIFLRELISN SDALDKI
Sbjct: 122 LMPEETQTQDQPMEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKI 181
Query: 500 RLMSLTDRGVLEANPELSIRIKAEPDKRLLHII 598
R SLTD L++ EL I + R L I+
Sbjct: 182 RYESLTDPSKLDSGRELHINLIPNKQGRTLTIV 214
>X15183-1|CAA33259.1| 732|Homo sapiens protein ( Human mRNA for
90-kDa heat-shock protein. ).
Length = 732
Score = 80.2 bits (189), Expect = 5e-15
Identities = 39/78 (50%), Positives = 51/78 (65%)
Frame = +2
Query: 365 DRAQNYTFQTEVNRMMKLIINSLYRNKEIFLRELISNGSDALDKIRLMSLTDRGVLEANP 544
+ + + FQ E+ ++M LIIN+ Y NKEIFLRELISN SDALDKIR +LTD L++
Sbjct: 15 EEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYETLTDPSKLDSGK 74
Query: 545 ELSIRIKAEPDKRLLHII 598
EL I + R L I+
Sbjct: 75 ELHINLIPNKQDRTLTIV 92
>AY956764-1|AAX38251.1| 597|Homo sapiens heat shock protein 90Bc
protein.
Length = 597
Score = 80.2 bits (189), Expect = 5e-15
Identities = 38/78 (48%), Positives = 53/78 (67%)
Frame = +2
Query: 365 DRAQNYTFQTEVNRMMKLIINSLYRNKEIFLRELISNGSDALDKIRLMSLTDRGVLEANP 544
+ + + FQ E+ +++ LIIN+ Y N+EIFL+ELISN SDALDKIR SLTD L++
Sbjct: 10 EEVETFAFQAEIAQLISLIINTFYSNEEIFLQELISNASDALDKIRYESLTDPSKLDSGK 69
Query: 545 ELSIRIKAEPDKRLLHII 598
EL I I P +R L ++
Sbjct: 70 ELKIDIIPNPQERTLALV 87
>AL139392-2|CAI20094.1| 168|Homo sapiens heat shock protein 90kDa
alpha (cytosolic), classr 11 protein.
Length = 168
Score = 79.0 bits (186), Expect = 1e-14
Identities = 38/66 (57%), Positives = 47/66 (71%)
Frame = +2
Query: 365 DRAQNYTFQTEVNRMMKLIINSLYRNKEIFLRELISNGSDALDKIRLMSLTDRGVLEANP 544
+ + + FQ E+ ++M LIIN+ Y NKEIFLRELISN SDALDKIR SLTD L++
Sbjct: 10 EEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGK 69
Query: 545 ELSIRI 562
EL I I
Sbjct: 70 ELKIDI 75
>M30627-1|AAA36024.1| 312|Homo sapiens heat shock protein 86
protein.
Length = 312
Score = 76.6 bits (180), Expect = 6e-14
Identities = 38/78 (48%), Positives = 50/78 (64%)
Frame = +2
Query: 365 DRAQNYTFQTEVNRMMKLIINSLYRNKEIFLRELISNGSDALDKIRLMSLTDRGVLEANP 544
+ + + FQ E+ ++M LIIN+ Y NKEIFLRELISN SDALDKI SLTD L++
Sbjct: 15 EEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIWYESLTDPSKLDSGK 74
Query: 545 ELSIRIKAEPDKRLLHII 598
EL I + + L I+
Sbjct: 75 ELHINLIPNKQDQTLTIV 92
>AY956763-1|AAX38250.1| 422|Homo sapiens heat shock protein 90Bb
protein.
Length = 422
Score = 75.8 bits (178), Expect = 1e-13
Identities = 38/75 (50%), Positives = 49/75 (65%)
Frame = +2
Query: 374 QNYTFQTEVNRMMKLIINSLYRNKEIFLRELISNGSDALDKIRLMSLTDRGVLEANPELS 553
+ + FQ E+ ++M LIIN+ Y NKEIFL ELISN SDALDKIR SLTD L++ EL
Sbjct: 54 ETFAFQAEIAQLMSLIINTFYSNKEIFLWELISNASDALDKIRYESLTDPSKLDSGKELK 113
Query: 554 IRIKAEPDKRLLHII 598
I I + L ++
Sbjct: 114 IDIIPNTQEHTLTLV 128
>AY956765-1|AAX38252.1| 505|Homo sapiens heat shock protein 90Bd
protein.
Length = 505
Score = 69.3 bits (162), Expect = 1e-11
Identities = 36/63 (57%), Positives = 43/63 (68%)
Frame = +2
Query: 410 MKLIINSLYRNKEIFLRELISNGSDALDKIRLMSLTDRGVLEANPELSIRIKAEPDKRLL 589
M LIIN+ Y NKEIFL+ELISN SDALDKIR SLTD L+ EL I I P + +L
Sbjct: 1 MSLIINTFYSNKEIFLQELISNASDALDKIRYESLTDPSKLDGGKELKIDIIPNPRECIL 60
Query: 590 HII 598
++
Sbjct: 61 TLV 63
>U12595-1|AAA87704.1| 661|Homo sapiens tumor necrosis factor type 1
receptor associated protein protein.
Length = 661
Score = 60.9 bits (141), Expect = 3e-09
Identities = 28/85 (32%), Positives = 51/85 (60%)
Frame = +2
Query: 341 VAQMKELRDRAQNYTFQTEVNRMMKLIINSLYRNKEIFLRELISNGSDALDKIRLMSLTD 520
++ + ++ + FQ E +++ ++ SLY KE+F+RELISN SDAL+K+R ++D
Sbjct: 60 ISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSD 119
Query: 521 RGVLEANPELSIRIKAEPDKRLLHI 595
+A PE+ I ++ +K + I
Sbjct: 120 G---QALPEMEIHLQTNAEKGTITI 141
>BC023585-1|AAH23585.1| 704|Homo sapiens TNF receptor-associated
protein 1 protein.
Length = 704
Score = 60.9 bits (141), Expect = 3e-09
Identities = 28/85 (32%), Positives = 51/85 (60%)
Frame = +2
Query: 341 VAQMKELRDRAQNYTFQTEVNRMMKLIINSLYRNKEIFLRELISNGSDALDKIRLMSLTD 520
++ + ++ + FQ E +++ ++ SLY KE+F+RELISN SDAL+K+R ++D
Sbjct: 75 ISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSD 134
Query: 521 RGVLEANPELSIRIKAEPDKRLLHI 595
+A PE+ I ++ +K + I
Sbjct: 135 G---QALPEMEIHLQTNAEKGTITI 156
>BC018950-1|AAH18950.1| 704|Homo sapiens TNF receptor-associated
protein 1 protein.
Length = 704
Score = 60.9 bits (141), Expect = 3e-09
Identities = 28/85 (32%), Positives = 51/85 (60%)
Frame = +2
Query: 341 VAQMKELRDRAQNYTFQTEVNRMMKLIINSLYRNKEIFLRELISNGSDALDKIRLMSLTD 520
++ + ++ + FQ E +++ ++ SLY KE+F+RELISN SDAL+K+R ++D
Sbjct: 75 ISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSD 134
Query: 521 RGVLEANPELSIRIKAEPDKRLLHI 595
+A PE+ I ++ +K + I
Sbjct: 135 G---QALPEMEIHLQTNAEKGTITI 156
>BC001455-1|AAH01455.2| 699|Homo sapiens TRAP1 protein protein.
Length = 699
Score = 60.9 bits (141), Expect = 3e-09
Identities = 28/85 (32%), Positives = 51/85 (60%)
Frame = +2
Query: 341 VAQMKELRDRAQNYTFQTEVNRMMKLIINSLYRNKEIFLRELISNGSDALDKIRLMSLTD 520
++ + ++ + FQ E +++ ++ SLY KE+F+RELISN SDAL+K+R ++D
Sbjct: 70 ISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSD 129
Query: 521 RGVLEANPELSIRIKAEPDKRLLHI 595
+A PE+ I ++ +K + I
Sbjct: 130 G---QALPEMEIHLQTNAEKGTITI 151
>AK223205-1|BAD96925.1| 704|Homo sapiens TNF receptor-associated
protein 1 variant protein.
Length = 704
Score = 60.9 bits (141), Expect = 3e-09
Identities = 28/85 (32%), Positives = 51/85 (60%)
Frame = +2
Query: 341 VAQMKELRDRAQNYTFQTEVNRMMKLIINSLYRNKEIFLRELISNGSDALDKIRLMSLTD 520
++ + ++ + FQ E +++ ++ SLY KE+F+RELISN SDAL+K+R ++D
Sbjct: 75 ISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSD 134
Query: 521 RGVLEANPELSIRIKAEPDKRLLHI 595
+A PE+ I ++ +K + I
Sbjct: 135 G---QALPEMEIHLQTNAEKGTITI 156
>AK223076-1|BAD96796.1| 704|Homo sapiens TNF receptor-associated
protein 1 variant protein.
Length = 704
Score = 60.9 bits (141), Expect = 3e-09
Identities = 28/85 (32%), Positives = 51/85 (60%)
Frame = +2
Query: 341 VAQMKELRDRAQNYTFQTEVNRMMKLIINSLYRNKEIFLRELISNGSDALDKIRLMSLTD 520
++ + ++ + FQ E +++ ++ SLY KE+F+RELISN SDAL+K+R ++D
Sbjct: 75 ISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSD 134
Query: 521 RGVLEANPELSIRIKAEPDKRLLHI 595
+A PE+ I ++ +K + I
Sbjct: 135 G---QALPEMEIHLQTNAEKGTITI 156
>AK223049-1|BAD96769.1| 704|Homo sapiens TNF receptor-associated
protein 1 variant protein.
Length = 704
Score = 60.9 bits (141), Expect = 3e-09
Identities = 28/85 (32%), Positives = 51/85 (60%)
Frame = +2
Query: 341 VAQMKELRDRAQNYTFQTEVNRMMKLIINSLYRNKEIFLRELISNGSDALDKIRLMSLTD 520
++ + ++ + FQ E +++ ++ SLY KE+F+RELISN SDAL+K+R ++D
Sbjct: 75 ISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSD 134
Query: 521 RGVLEANPELSIRIKAEPDKRLLHI 595
+A PE+ I ++ +K + I
Sbjct: 135 G---QALPEMEIHLQTNAEKGTITI 156
>AF154108-1|AAF15314.1| 704|Homo sapiens tumor necrosis factor type
1 receptor associated protein protein.
Length = 704
Score = 60.9 bits (141), Expect = 3e-09
Identities = 28/85 (32%), Positives = 51/85 (60%)
Frame = +2
Query: 341 VAQMKELRDRAQNYTFQTEVNRMMKLIINSLYRNKEIFLRELISNGSDALDKIRLMSLTD 520
++ + ++ + FQ E +++ ++ SLY KE+F+RELISN SDAL+K+R ++D
Sbjct: 75 ISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSD 134
Query: 521 RGVLEANPELSIRIKAEPDKRLLHI 595
+A PE+ I ++ +K + I
Sbjct: 135 G---QALPEMEIHLQTNAEKGTITI 156
>AF043254-1|AAC02679.1| 649|Homo sapiens heat shock protein 75
protein.
Length = 649
Score = 60.9 bits (141), Expect = 3e-09
Identities = 28/85 (32%), Positives = 51/85 (60%)
Frame = +2
Query: 341 VAQMKELRDRAQNYTFQTEVNRMMKLIINSLYRNKEIFLRELISNGSDALDKIRLMSLTD 520
++ + ++ + FQ E +++ ++ SLY KE+F+RELISN SDAL+K+R ++D
Sbjct: 23 ISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSD 82
Query: 521 RGVLEANPELSIRIKAEPDKRLLHI 595
+A PE+ I ++ +K + I
Sbjct: 83 G---QALPEMEIHLQTNAEKGTITI 104
>AC005203-2|AAC24722.1| 616|Homo sapiens TRAP1 protein.
Length = 616
Score = 60.9 bits (141), Expect = 3e-09
Identities = 28/85 (32%), Positives = 51/85 (60%)
Frame = +2
Query: 341 VAQMKELRDRAQNYTFQTEVNRMMKLIINSLYRNKEIFLRELISNGSDALDKIRLMSLTD 520
++ + ++ + FQ E +++ ++ SLY KE+F+RELISN SDAL+K+R ++D
Sbjct: 45 ISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSD 104
Query: 521 RGVLEANPELSIRIKAEPDKRLLHI 595
+A PE+ I ++ +K + I
Sbjct: 105 G---QALPEMEIHLQTNAEKGTITI 126
>AB209805-1|BAD93042.1| 703|Homo sapiens TNF receptor-associated
protein 1 variant protein.
Length = 703
Score = 60.9 bits (141), Expect = 3e-09
Identities = 28/85 (32%), Positives = 51/85 (60%)
Frame = +2
Query: 341 VAQMKELRDRAQNYTFQTEVNRMMKLIINSLYRNKEIFLRELISNGSDALDKIRLMSLTD 520
++ + ++ + FQ E +++ ++ SLY KE+F+RELISN SDAL+K+R ++D
Sbjct: 74 ISSTESVQGSTSKHEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSD 133
Query: 521 RGVLEANPELSIRIKAEPDKRLLHI 595
+A PE+ I ++ +K + I
Sbjct: 134 G---QALPEMEIHLQTNAEKGTITI 155
>AK093344-1|BAC04139.1| 579|Homo sapiens protein ( Homo sapiens
cDNA FLJ36025 fis, clone TESTI2016701, highly similar to
TUMOR NECROSIS FACTOR TYPE 1 RECEPTOR ASSOCIATED
PROTEIN. ).
Length = 579
Score = 59.3 bits (137), Expect = 1e-08
Identities = 28/72 (38%), Positives = 46/72 (63%)
Frame = +2
Query: 380 YTFQTEVNRMMKLIINSLYRNKEIFLRELISNGSDALDKIRLMSLTDRGVLEANPELSIR 559
+ FQ E +++ ++ SLY KE+F+RELISN SDAL+K+R ++D +A PE+ I
Sbjct: 81 HEFQAETKKLLDIVARSLYSEKEVFIRELISNASDALEKLRHKLVSDG---QALPEMEIH 137
Query: 560 IKAEPDKRLLHI 595
++ +K + I
Sbjct: 138 LQTNAEKGTITI 149
>D17804-1|BAA22050.1| 130|Homo sapiens heat shock protein beta
protein.
Length = 130
Score = 34.7 bits (76), Expect = 0.25
Identities = 18/38 (47%), Positives = 23/38 (60%)
Frame = +2
Query: 485 ALDKIRLMSLTDRGVLEANPELSIRIKAEPDKRLLHII 598
ALDKIR SLTD L++ EL I I P +R L ++
Sbjct: 1 ALDKIRYESLTDPSKLDSGKELKIDIIPNPQERTLTLV 38
>S70561-1|AAD14062.1| 68|Homo sapiens 90-kda heat shock protein
beta HSP90 beta protein.
Length = 68
Score = 33.1 bits (72), Expect = 0.77
Identities = 17/37 (45%), Positives = 22/37 (59%)
Frame = +2
Query: 488 LDKIRLMSLTDRGVLEANPELSIRIKAEPDKRLLHII 598
LDKIR SLTD L++ EL I I P +R L ++
Sbjct: 1 LDKIRYESLTDPSKLDSGKELKIDIIPNPQERTLTLV 37
>BC086869-1|AAH86869.1| 954|Homo sapiens FLJ25770 protein protein.
Length = 954
Score = 29.9 bits (64), Expect = 7.1
Identities = 18/63 (28%), Positives = 34/63 (53%)
Frame = +2
Query: 383 TFQTEVNRMMKLIINSLYRNKEIFLRELISNGSDALDKIRLMSLTDRGVLEANPELSIRI 562
T TE N+M + + R++E L+E ++N ALDK L + +++ + S+R+
Sbjct: 621 TVATEKNKMAGEL--EVLRSQERRLKEKVTNMEVALDKASLQFAECQDIIQRQEQESVRL 678
Query: 563 KAE 571
K +
Sbjct: 679 KLQ 681
>AK098600-1|BAC05347.1| 424|Homo sapiens protein ( Homo sapiens
cDNA FLJ25734 fis, clone TST05668. ).
Length = 424
Score = 29.9 bits (64), Expect = 7.1
Identities = 18/63 (28%), Positives = 34/63 (53%)
Frame = +2
Query: 383 TFQTEVNRMMKLIINSLYRNKEIFLRELISNGSDALDKIRLMSLTDRGVLEANPELSIRI 562
T TE N+M + + R++E L+E ++N ALDK L + +++ + S+R+
Sbjct: 91 TVATEKNKMAGEL--EVLRSQERRLKEKVTNMEVALDKASLQFAECQDIIQRQEQESVRL 148
Query: 563 KAE 571
K +
Sbjct: 149 KLQ 151
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 68,290,195
Number of Sequences: 237096
Number of extensions: 1186788
Number of successful extensions: 3110
Number of sequences better than 10.0: 48
Number of HSP's better than 10.0 without gapping: 3073
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3110
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 6297951520
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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