Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= bmnc13d22
(567 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC000096-1|AAH00096.1| 458|Homo sapiens HtrA serine peptidase 2... 83 9e-16
AF184911-1|AAG13126.1| 361|Homo sapiens serine protease protein. 83 9e-16
AF141307-1|AAF66598.1| 323|Homo sapiens serine protease HtrA2-p... 83 9e-16
AF141306-1|AAF66597.1| 423|Homo sapiens serine protease HtrA2-p... 83 9e-16
AF141305-1|AAF66596.1| 458|Homo sapiens serine protease Htra2 p... 83 9e-16
AF020760-1|AAB94569.2| 458|Homo sapiens serine protease protein. 83 9e-16
Y07921-1|CAA69226.1| 480|Homo sapiens novel serine protease, PR... 78 2e-14
D87258-1|BAA13322.1| 480|Homo sapiens serin protease with IGF-b... 78 2e-14
BC011352-1|AAH11352.1| 445|Homo sapiens HTRA1 protein protein. 78 2e-14
AF157623-1|AAD41525.1| 480|Homo sapiens HTRA serine protease pr... 78 2e-14
AF097709-1|AAC97211.1| 337|Homo sapiens serine protease protein. 78 2e-14
BC035717-1|AAH35717.1| 453|Homo sapiens HtrA serine peptidase 3... 68 3e-11
BC034390-1|AAH34390.1| 453|Homo sapiens HtrA serine peptidase 3... 68 3e-11
AY280666-1|AAP42283.1| 357|Homo sapiens pregnancy-related serin... 68 3e-11
AY280665-1|AAP42282.1| 453|Homo sapiens pregnancy-related serin... 68 3e-11
AY040094-1|AAK71475.2| 453|Homo sapiens serine protease HTRA3 p... 68 3e-11
BC057765-1|AAH57765.1| 476|Homo sapiens HtrA serine peptidase 4... 61 2e-09
AK075205-1|BAC11470.1| 476|Homo sapiens protein ( Homo sapiens ... 61 2e-09
>BC000096-1|AAH00096.1| 458|Homo sapiens HtrA serine peptidase 2
protein.
Length = 458
Score = 82.6 bits (195), Expect = 9e-16
Identities = 44/94 (46%), Positives = 60/94 (63%)
Frame = +2
Query: 284 REKYNFIADXXXXXXXXXXYIEIVDGRRIDAFTGKKLKISNGSGFIIKEDGLILTNAHVV 463
R +YNFIAD YIEI+D F G+++ ISNGSGF++ DGLI+TNAHVV
Sbjct: 144 RSQYNFIADVVEKTAPAVVYIEILDRH---PFLGREVPISNGSGFVVAADGLIVTNAHVV 200
Query: 464 VNKPNAIVKVRLTDGSTHEALIEHYDLQSDLATL 565
++ V+VRL G T+EA++ D +D+ATL
Sbjct: 201 ADRRR--VRVRLLSGDTYEAVVTAVDPVADIATL 232
>AF184911-1|AAG13126.1| 361|Homo sapiens serine protease protein.
Length = 361
Score = 82.6 bits (195), Expect = 9e-16
Identities = 44/94 (46%), Positives = 60/94 (63%)
Frame = +2
Query: 284 REKYNFIADXXXXXXXXXXYIEIVDGRRIDAFTGKKLKISNGSGFIIKEDGLILTNAHVV 463
R +YNFIAD YIEI+D F G+++ ISNGSGF++ DGLI+TNAHVV
Sbjct: 144 RSQYNFIADVVEKTAPAVVYIEILDRH---PFLGREVPISNGSGFVVAADGLIVTNAHVV 200
Query: 464 VNKPNAIVKVRLTDGSTHEALIEHYDLQSDLATL 565
++ V+VRL G T+EA++ D +D+ATL
Sbjct: 201 ADRRR--VRVRLLSGDTYEAVVTAVDPVADIATL 232
>AF141307-1|AAF66598.1| 323|Homo sapiens serine protease HtrA2-p4
protein.
Length = 323
Score = 82.6 bits (195), Expect = 9e-16
Identities = 44/94 (46%), Positives = 60/94 (63%)
Frame = +2
Query: 284 REKYNFIADXXXXXXXXXXYIEIVDGRRIDAFTGKKLKISNGSGFIIKEDGLILTNAHVV 463
R +YNFIAD YIEI+D F G+++ ISNGSGF++ DGLI+TNAHVV
Sbjct: 90 RSQYNFIADVVEKTAPAVVYIEILDRH---PFLGREVPISNGSGFVVAADGLIVTNAHVV 146
Query: 464 VNKPNAIVKVRLTDGSTHEALIEHYDLQSDLATL 565
++ V+VRL G T+EA++ D +D+ATL
Sbjct: 147 ADRRR--VRVRLLSGDTYEAVVTAVDPVADIATL 178
>AF141306-1|AAF66597.1| 423|Homo sapiens serine protease HtrA2-p7
protein.
Length = 423
Score = 82.6 bits (195), Expect = 9e-16
Identities = 44/94 (46%), Positives = 60/94 (63%)
Frame = +2
Query: 284 REKYNFIADXXXXXXXXXXYIEIVDGRRIDAFTGKKLKISNGSGFIIKEDGLILTNAHVV 463
R +YNFIAD YIEI+D F G+++ ISNGSGF++ DGLI+TNAHVV
Sbjct: 131 RSQYNFIADVVEKTAPAVVYIEILDRH---PFLGREVPISNGSGFVVAADGLIVTNAHVV 187
Query: 464 VNKPNAIVKVRLTDGSTHEALIEHYDLQSDLATL 565
++ V+VRL G T+EA++ D +D+ATL
Sbjct: 188 ADRRR--VRVRLLSGDTYEAVVTAVDPVADIATL 219
>AF141305-1|AAF66596.1| 458|Homo sapiens serine protease Htra2
protein.
Length = 458
Score = 82.6 bits (195), Expect = 9e-16
Identities = 44/94 (46%), Positives = 60/94 (63%)
Frame = +2
Query: 284 REKYNFIADXXXXXXXXXXYIEIVDGRRIDAFTGKKLKISNGSGFIIKEDGLILTNAHVV 463
R +YNFIAD YIEI+D F G+++ ISNGSGF++ DGLI+TNAHVV
Sbjct: 144 RSQYNFIADVVEKTAPAVVYIEILDRH---PFLGREVPISNGSGFVVAADGLIVTNAHVV 200
Query: 464 VNKPNAIVKVRLTDGSTHEALIEHYDLQSDLATL 565
++ V+VRL G T+EA++ D +D+ATL
Sbjct: 201 ADRRR--VRVRLLSGDTYEAVVTAVDPVADIATL 232
>AF020760-1|AAB94569.2| 458|Homo sapiens serine protease protein.
Length = 458
Score = 82.6 bits (195), Expect = 9e-16
Identities = 44/94 (46%), Positives = 60/94 (63%)
Frame = +2
Query: 284 REKYNFIADXXXXXXXXXXYIEIVDGRRIDAFTGKKLKISNGSGFIIKEDGLILTNAHVV 463
R +YNFIAD YIEI+D F G+++ ISNGSGF++ DGLI+TNAHVV
Sbjct: 144 RSQYNFIADVVEKTAPAVVYIEILDRH---PFLGREVPISNGSGFVVAADGLIVTNAHVV 200
Query: 464 VNKPNAIVKVRLTDGSTHEALIEHYDLQSDLATL 565
++ V+VRL G T+EA++ D +D+ATL
Sbjct: 201 ADRRR--VRVRLLSGDTYEAVVTAVDPVADIATL 232
>Y07921-1|CAA69226.1| 480|Homo sapiens novel serine protease,
PRSS11 protein.
Length = 480
Score = 78.2 bits (184), Expect = 2e-14
Identities = 43/99 (43%), Positives = 64/99 (64%)
Frame = +2
Query: 269 DLKGRREKYNFIADXXXXXXXXXXYIEIVDGRRIDAFTGKKLKISNGSGFIIKEDGLILT 448
D R KYNFIAD +IE+ R++ F+ +++ +++GSGFI+ EDGLI+T
Sbjct: 161 DPNSLRHKYNFIADVVEKIAPAVVHIELF--RKLP-FSKREVPVASGSGFIVSEDGLIVT 217
Query: 449 NAHVVVNKPNAIVKVRLTDGSTHEALIEHYDLQSDLATL 565
NAHVV NK VKV L +G+T+EA I+ D ++D+A +
Sbjct: 218 NAHVVTNKHR--VKVELKNGATYEAKIKDVDEKADIALI 254
>D87258-1|BAA13322.1| 480|Homo sapiens serin protease with
IGF-binding motif protein.
Length = 480
Score = 78.2 bits (184), Expect = 2e-14
Identities = 43/99 (43%), Positives = 64/99 (64%)
Frame = +2
Query: 269 DLKGRREKYNFIADXXXXXXXXXXYIEIVDGRRIDAFTGKKLKISNGSGFIIKEDGLILT 448
D R KYNFIAD +IE+ R++ F+ +++ +++GSGFI+ EDGLI+T
Sbjct: 161 DPNSLRHKYNFIADVVEKIAPAVVHIELF--RKLP-FSKREVPVASGSGFIVSEDGLIVT 217
Query: 449 NAHVVVNKPNAIVKVRLTDGSTHEALIEHYDLQSDLATL 565
NAHVV NK VKV L +G+T+EA I+ D ++D+A +
Sbjct: 218 NAHVVTNKHR--VKVELKNGATYEAKIKDVDEKADIALI 254
>BC011352-1|AAH11352.1| 445|Homo sapiens HTRA1 protein protein.
Length = 445
Score = 78.2 bits (184), Expect = 2e-14
Identities = 43/99 (43%), Positives = 64/99 (64%)
Frame = +2
Query: 269 DLKGRREKYNFIADXXXXXXXXXXYIEIVDGRRIDAFTGKKLKISNGSGFIIKEDGLILT 448
D R KYNFIAD +IE+ R++ F+ +++ +++GSGFI+ EDGLI+T
Sbjct: 126 DPNSLRHKYNFIADVVEKIAPAVVHIELF--RKLP-FSKREVPVASGSGFIVSEDGLIVT 182
Query: 449 NAHVVVNKPNAIVKVRLTDGSTHEALIEHYDLQSDLATL 565
NAHVV NK VKV L +G+T+EA I+ D ++D+A +
Sbjct: 183 NAHVVTNKHR--VKVELKNGATYEAKIKDVDEKADIALI 219
>AF157623-1|AAD41525.1| 480|Homo sapiens HTRA serine protease
protein.
Length = 480
Score = 78.2 bits (184), Expect = 2e-14
Identities = 43/99 (43%), Positives = 64/99 (64%)
Frame = +2
Query: 269 DLKGRREKYNFIADXXXXXXXXXXYIEIVDGRRIDAFTGKKLKISNGSGFIIKEDGLILT 448
D R KYNFIAD +IE+ R++ F+ +++ +++GSGFI+ EDGLI+T
Sbjct: 161 DPNSLRHKYNFIADVVEKIAPAVVHIELF--RKLP-FSKREVPVASGSGFIVSEDGLIVT 217
Query: 449 NAHVVVNKPNAIVKVRLTDGSTHEALIEHYDLQSDLATL 565
NAHVV NK VKV L +G+T+EA I+ D ++D+A +
Sbjct: 218 NAHVVTNKHR--VKVELKNGATYEAKIKDVDEKADIALI 254
>AF097709-1|AAC97211.1| 337|Homo sapiens serine protease protein.
Length = 337
Score = 78.2 bits (184), Expect = 2e-14
Identities = 43/99 (43%), Positives = 64/99 (64%)
Frame = +2
Query: 269 DLKGRREKYNFIADXXXXXXXXXXYIEIVDGRRIDAFTGKKLKISNGSGFIIKEDGLILT 448
D R KYNFIAD +IE+ R++ F+ +++ +++GSGFI+ EDGLI+T
Sbjct: 18 DPNSLRHKYNFIADVVEKIAPAVVHIELF--RKLP-FSKREVPVASGSGFIVSEDGLIVT 74
Query: 449 NAHVVVNKPNAIVKVRLTDGSTHEALIEHYDLQSDLATL 565
NAHVV NK VKV L +G+T+EA I+ D ++D+A +
Sbjct: 75 NAHVVTNKHR--VKVELKNGATYEAKIKDVDEKADIALI 111
>BC035717-1|AAH35717.1| 453|Homo sapiens HtrA serine peptidase 3
protein.
Length = 453
Score = 67.7 bits (158), Expect = 3e-11
Identities = 42/105 (40%), Positives = 63/105 (60%), Gaps = 4/105 (3%)
Frame = +2
Query: 263 VNDLKGRREKYNFIADXXXXXXXXXXYIEIVDGRRIDAFTGKKLKISNGSGFIIKEDGLI 442
++ L R K+NFIAD +IE+ R F G+ + +S+GSGFI+ E GLI
Sbjct: 130 LHQLSSPRYKFNFIADVVEKIAPAVVHIELF--LRHPLF-GRNVPLSSGSGFIMSEAGLI 186
Query: 443 LTNAHVVVNKPNA----IVKVRLTDGSTHEALIEHYDLQSDLATL 565
+TNAHVV + A +KV+L +G ++EA I+ D +SD+AT+
Sbjct: 187 ITNAHVVSSNSAAPGRQQLKVQLQNGDSYEATIKDIDKKSDIATI 231
>BC034390-1|AAH34390.1| 453|Homo sapiens HtrA serine peptidase 3
protein.
Length = 453
Score = 67.7 bits (158), Expect = 3e-11
Identities = 42/105 (40%), Positives = 63/105 (60%), Gaps = 4/105 (3%)
Frame = +2
Query: 263 VNDLKGRREKYNFIADXXXXXXXXXXYIEIVDGRRIDAFTGKKLKISNGSGFIIKEDGLI 442
++ L R K+NFIAD +IE+ R F G+ + +S+GSGFI+ E GLI
Sbjct: 130 LHQLSSPRYKFNFIADVVEKIAPAVVHIELF--LRHPLF-GRNVPLSSGSGFIMSEAGLI 186
Query: 443 LTNAHVVVNKPNA----IVKVRLTDGSTHEALIEHYDLQSDLATL 565
+TNAHVV + A +KV+L +G ++EA I+ D +SD+AT+
Sbjct: 187 ITNAHVVSSNSAAPGRQQLKVQLQNGDSYEATIKDIDKKSDIATI 231
>AY280666-1|AAP42283.1| 357|Homo sapiens pregnancy-related serine
protease HTRA3 protein.
Length = 357
Score = 67.7 bits (158), Expect = 3e-11
Identities = 42/105 (40%), Positives = 63/105 (60%), Gaps = 4/105 (3%)
Frame = +2
Query: 263 VNDLKGRREKYNFIADXXXXXXXXXXYIEIVDGRRIDAFTGKKLKISNGSGFIIKEDGLI 442
++ L R K+NFIAD +IE+ R F G+ + +S+GSGFI+ E GLI
Sbjct: 130 LHQLSSPRYKFNFIADVVEKIAPAVVHIELF--LRHPLF-GRNVPLSSGSGFIMSEAGLI 186
Query: 443 LTNAHVVVNKPNA----IVKVRLTDGSTHEALIEHYDLQSDLATL 565
+TNAHVV + A +KV+L +G ++EA I+ D +SD+AT+
Sbjct: 187 ITNAHVVSSNSAAPGRQQLKVQLQNGDSYEATIKDIDKKSDIATI 231
>AY280665-1|AAP42282.1| 453|Homo sapiens pregnancy-related serine
protease HTRA3 protein.
Length = 453
Score = 67.7 bits (158), Expect = 3e-11
Identities = 42/105 (40%), Positives = 63/105 (60%), Gaps = 4/105 (3%)
Frame = +2
Query: 263 VNDLKGRREKYNFIADXXXXXXXXXXYIEIVDGRRIDAFTGKKLKISNGSGFIIKEDGLI 442
++ L R K+NFIAD +IE+ R F G+ + +S+GSGFI+ E GLI
Sbjct: 130 LHQLSSPRYKFNFIADVVEKIAPAVVHIELF--LRHPLF-GRNVPLSSGSGFIMSEAGLI 186
Query: 443 LTNAHVVVNKPNA----IVKVRLTDGSTHEALIEHYDLQSDLATL 565
+TNAHVV + A +KV+L +G ++EA I+ D +SD+AT+
Sbjct: 187 ITNAHVVSSNSAAPGRQQLKVQLQNGDSYEATIKDIDKKSDIATI 231
>AY040094-1|AAK71475.2| 453|Homo sapiens serine protease HTRA3
protein.
Length = 453
Score = 67.7 bits (158), Expect = 3e-11
Identities = 42/105 (40%), Positives = 63/105 (60%), Gaps = 4/105 (3%)
Frame = +2
Query: 263 VNDLKGRREKYNFIADXXXXXXXXXXYIEIVDGRRIDAFTGKKLKISNGSGFIIKEDGLI 442
++ L R K+NFIAD +IE+ R F G+ + +S+GSGFI+ E GLI
Sbjct: 130 LHQLSSPRYKFNFIADVVEKIAPAVVHIELF--LRHPLF-GRNVPLSSGSGFIMSEAGLI 186
Query: 443 LTNAHVVVNKPNA----IVKVRLTDGSTHEALIEHYDLQSDLATL 565
+TNAHVV + A +KV+L +G ++EA I+ D +SD+AT+
Sbjct: 187 ITNAHVVSSNSAAPGRQQLKVQLQNGDSYEATIKDIDKKSDIATI 231
>BC057765-1|AAH57765.1| 476|Homo sapiens HtrA serine peptidase 4
protein.
Length = 476
Score = 61.3 bits (142), Expect = 2e-09
Identities = 35/94 (37%), Positives = 57/94 (60%)
Frame = +2
Query: 284 REKYNFIADXXXXXXXXXXYIEIVDGRRIDAFTGKKLKISNGSGFIIKEDGLILTNAHVV 463
R YNFIA ++++ GR + + + + +GSGFI+ EDGLI+TNAHVV
Sbjct: 164 RRNYNFIAAVVEKVAPSVVHVQLW-GRLLHG--SRLVPVYSGSGFIVSEDGLIITNAHVV 220
Query: 464 VNKPNAIVKVRLTDGSTHEALIEHYDLQSDLATL 565
N+ ++V L +G+ +EA+++ DL+ DLA +
Sbjct: 221 RNQ--QWIEVVLQNGARYEAVVKDIDLKLDLAVI 252
>AK075205-1|BAC11470.1| 476|Homo sapiens protein ( Homo sapiens
cDNA FLJ90724 fis, clone PLACE1009279, highly similar to
Probable serine protease HTRA4 precursor (EC3.4.21.-).
).
Length = 476
Score = 61.3 bits (142), Expect = 2e-09
Identities = 35/94 (37%), Positives = 57/94 (60%)
Frame = +2
Query: 284 REKYNFIADXXXXXXXXXXYIEIVDGRRIDAFTGKKLKISNGSGFIIKEDGLILTNAHVV 463
R YNFIA ++++ GR + + + + +GSGFI+ EDGLI+TNAHVV
Sbjct: 164 RRNYNFIAAVVEKVAPSVVHVQLW-GRLLHG--SRLVPVYSGSGFIVSEDGLIITNAHVV 220
Query: 464 VNKPNAIVKVRLTDGSTHEALIEHYDLQSDLATL 565
N+ ++V L +G+ +EA+++ DL+ DLA +
Sbjct: 221 RNQ--QWIEVVLQNGARYEAVVKDIDLKLDLAVI 252
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 68,575,270
Number of Sequences: 237096
Number of extensions: 1252482
Number of successful extensions: 1749
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 1716
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 1722
length of database: 76,859,062
effective HSP length: 86
effective length of database: 56,468,806
effective search space used: 5759818212
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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