Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= bmnc10d12
(683 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X05344-1|CAA28955.1| 412|Homo sapiens cathepsin D protein. 159 1e-38
M63138-1|AAA51922.1| 412|Homo sapiens cathepsin D protein. 159 1e-38
M11233-1|AAB59529.1| 412|Homo sapiens CTSD protein. 159 1e-38
CR456947-1|CAG33228.1| 412|Homo sapiens CTSD protein. 159 1e-38
BT020155-1|AAV38957.1| 412|Homo sapiens cathepsin D (lysosomal ... 159 1e-38
BT006910-1|AAP35556.1| 412|Homo sapiens cathepsin D (lysosomal ... 159 1e-38
BC016320-1|AAH16320.1| 412|Homo sapiens cathepsin D protein. 159 1e-38
BC017842-1|AAH17842.1| 420|Homo sapiens napsin A aspartic pepti... 147 4e-35
AF200345-1|AAF17081.1| 420|Homo sapiens aspartyl protease 4 pro... 146 5e-35
AF098484-1|AAD13215.1| 420|Homo sapiens napsin 1 precursor prot... 146 5e-35
AF090386-1|AAD04917.1| 420|Homo sapiens napsin A protein. 146 5e-35
BC111705-1|AAI11706.1| 464|Homo sapiens NAPSB protein protein. 136 7e-32
AF200344-1|AAF17080.1| 450|Homo sapiens aspartyl protease 3 pro... 136 7e-32
M26901-1|AAA60364.1| 403|Homo sapiens renin protein. 128 1e-29
M10152-1|AAD03461.1| 406|Homo sapiens renin protein. 128 1e-29
L00073-1|AAA60363.1| 406|Homo sapiens renin protein. 128 1e-29
CR536498-1|CAG38737.1| 406|Homo sapiens REN protein. 128 1e-29
BC047752-1|AAH47752.1| 406|Homo sapiens renin protein. 128 1e-29
BC033474-1|AAH33474.1| 406|Homo sapiens renin protein. 128 1e-29
AY436324-1|AAR03502.1| 403|Homo sapiens renin protein. 128 1e-29
AL592146-1|CAI16594.1| 406|Homo sapiens renin protein. 128 1e-29
AL592114-1|CAH71224.1| 406|Homo sapiens renin protein. 128 1e-29
J00287-1|AAA98529.1| 388|Homo sapiens PEP protein. 120 6e-27
BC029055-1|AAH29055.1| 388|Homo sapiens pepsinogen 5, group I (... 120 6e-27
U75272-1|AAB18273.1| 388|Homo sapiens gastricsin protein. 119 8e-27
M84424-1|AAA52300.1| 396|Homo sapiens cathepsin E protein. 119 8e-27
M23077-1|AAA60063.1| 388|Homo sapiens pepsinogen C protein. 119 8e-27
M18667-1|AAA60062.1| 385|Homo sapiens pepsinogen protein. 119 8e-27
J05036-1|AAA52130.1| 396|Homo sapiens CTSE protein. 119 8e-27
J04443-1|AAA60074.1| 388|Homo sapiens pepsinogen protein. 119 8e-27
BX571818-5|CAH73265.1| 363|Homo sapiens cathepsin E protein. 119 8e-27
BX571818-4|CAH73264.1| 396|Homo sapiens cathepsin E protein. 119 8e-27
BC073740-1|AAH73740.1| 388|Homo sapiens progastricsin (pepsinog... 119 8e-27
BC042537-1|AAH42537.1| 396|Homo sapiens cathepsin E protein. 119 8e-27
AL365205-1|CAI13181.1| 388|Homo sapiens progastricsin (pepsinog... 119 8e-27
AJ250717-1|CAB82850.1| 396|Homo sapiens procathepsin E protein. 119 8e-27
AJ250716-1|CAB82849.1| 363|Homo sapiens cathepsin E, alternativ... 119 8e-27
M26032-1|AAA60061.1| 388|Homo sapiens pepsinogen A protein. 118 2e-26
X00063-1|CAA24937.1| 300|Homo sapiens protein ( Human kidney mR... 75 2e-13
BC042578-1|AAH42578.1| 104|Homo sapiens PGC protein protein. 60 7e-09
BC014453-1|AAH14453.1| 518|Homo sapiens beta-site APP-cleaving ... 54 4e-07
AY358927-1|AAQ89286.1| 518|Homo sapiens BACE2 protein. 54 4e-07
AF212252-1|AAG41783.1| 439|Homo sapiens CDA13 protein. 54 4e-07
AF204944-1|AAF26368.1| 518|Homo sapiens transmembrane aspartic ... 54 4e-07
AF200342-1|AAF17078.1| 518|Homo sapiens aspartyl protease 1 pro... 54 4e-07
AF200192-1|AAF13714.1| 518|Homo sapiens memapsin 1 protein. 54 4e-07
AF188277-1|AAF35836.1| 396|Homo sapiens aspartyl protease protein. 54 4e-07
AF188276-1|AAF35835.1| 468|Homo sapiens aspartyl protease protein. 54 4e-07
AF178532-1|AAF29494.1| 518|Homo sapiens aspartyl protease protein. 54 4e-07
AF117892-1|AAD45240.1| 518|Homo sapiens aspartic-like protease ... 54 4e-07
AF050171-1|AAD45963.1| 518|Homo sapiens aspartyl protease protein. 54 4e-07
AK075539-1|BAC11682.1| 423|Homo sapiens protein ( Homo sapiens ... 52 3e-06
DQ007053-1|AAY16982.1| 501|Homo sapiens beta-site APP-cleaving ... 42 0.002
BC065492-1|AAH65492.1| 501|Homo sapiens beta-site APP-cleaving ... 42 0.002
AF338816-1|AAK38374.1| 476|Homo sapiens beta-site APP cleaving ... 42 0.002
AF204943-1|AAF26367.1| 501|Homo sapiens transmembrane aspartic ... 42 0.002
AF201468-1|AAF18982.1| 501|Homo sapiens APP beta-secretase prot... 42 0.002
AF200343-1|AAF17079.1| 501|Homo sapiens aspartyl protease 2 pro... 42 0.002
AF200193-1|AAF13715.1| 488|Homo sapiens memapsin 2 protein. 42 0.002
AF190725-1|AAF04142.1| 501|Homo sapiens beta-site APP cleaving ... 42 0.002
AB050436-1|BAB40931.1| 476|Homo sapiens beta-site APP cleaving ... 42 0.002
AB032975-1|BAA86463.2| 532|Homo sapiens KIAA1149 protein protein. 42 0.002
AF338817-1|AAK38375.1| 457|Homo sapiens beta-site APP cleaving ... 41 0.005
AB050438-1|BAB40933.1| 432|Homo sapiens beta-site APP cleaving ... 41 0.005
AB050437-1|BAB40932.1| 457|Homo sapiens beta-site APP cleaving ... 41 0.005
BC036084-1|AAH36084.1| 501|Homo sapiens beta-site APP-cleaving ... 40 0.008
AL365205-3|CAM16152.1| 86|Homo sapiens progastricsin (pepsinog... 39 0.019
AL163285-1|CAB90554.1| 415|Homo sapiens beta-site APP-cleaving ... 38 0.033
AB089958-1|BAC81826.1| 127|Homo sapiens beta-site APP cleaving ... 36 0.18
BC030606-1|AAH30606.2| 514|Homo sapiens coiled-coil domain cont... 31 5.0
BC104851-1|AAI04852.1| 147|Homo sapiens LOC283174 protein protein. 30 6.7
BC101691-1|AAI01692.1| 147|Homo sapiens LOC283174 protein protein. 30 6.7
>X05344-1|CAA28955.1| 412|Homo sapiens cathepsin D protein.
Length = 412
Score = 159 bits (385), Expect = 1e-38
Identities = 88/167 (52%), Positives = 105/167 (62%), Gaps = 22/167 (13%)
Frame = +1
Query: 247 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 393
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 394 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTS 573
L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS C +IAC +H+KY+S KS++
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSST 130
Query: 574 YVANGTQFAIQYGSGSLSGFLSTDDVTV-----------GGLKVRRQ 681
YV NGT F I YGSGSLSG+LS D V+V GG+KV RQ
Sbjct: 131 YVKNGTSFDIHYGSGSLSGYLSQDTVSVPCQSASSASALGGVKVERQ 177
>M63138-1|AAA51922.1| 412|Homo sapiens cathepsin D protein.
Length = 412
Score = 159 bits (385), Expect = 1e-38
Identities = 88/167 (52%), Positives = 105/167 (62%), Gaps = 22/167 (13%)
Frame = +1
Query: 247 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 393
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 394 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTS 573
L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS C +IAC +H+KY+S KS++
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSST 130
Query: 574 YVANGTQFAIQYGSGSLSGFLSTDDVTV-----------GGLKVRRQ 681
YV NGT F I YGSGSLSG+LS D V+V GG+KV RQ
Sbjct: 131 YVKNGTSFDIHYGSGSLSGYLSQDTVSVPCQSASSASALGGVKVERQ 177
>M11233-1|AAB59529.1| 412|Homo sapiens CTSD protein.
Length = 412
Score = 159 bits (385), Expect = 1e-38
Identities = 88/167 (52%), Positives = 105/167 (62%), Gaps = 22/167 (13%)
Frame = +1
Query: 247 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 393
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 394 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTS 573
L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS C +IAC +H+KY+S KS++
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSST 130
Query: 574 YVANGTQFAIQYGSGSLSGFLSTDDVTV-----------GGLKVRRQ 681
YV NGT F I YGSGSLSG+LS D V+V GG+KV RQ
Sbjct: 131 YVKNGTSFDIHYGSGSLSGYLSQDTVSVPCQSASSASALGGVKVERQ 177
>CR456947-1|CAG33228.1| 412|Homo sapiens CTSD protein.
Length = 412
Score = 159 bits (385), Expect = 1e-38
Identities = 88/167 (52%), Positives = 105/167 (62%), Gaps = 22/167 (13%)
Frame = +1
Query: 247 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 393
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 394 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTS 573
L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS C +IAC +H+KY+S KS++
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSST 130
Query: 574 YVANGTQFAIQYGSGSLSGFLSTDDVTV-----------GGLKVRRQ 681
YV NGT F I YGSGSLSG+LS D V+V GG+KV RQ
Sbjct: 131 YVKNGTSFDIHYGSGSLSGYLSQDTVSVPCQSASSASALGGVKVERQ 177
>BT020155-1|AAV38957.1| 412|Homo sapiens cathepsin D (lysosomal
aspartyl protease) protein.
Length = 412
Score = 159 bits (385), Expect = 1e-38
Identities = 88/167 (52%), Positives = 105/167 (62%), Gaps = 22/167 (13%)
Frame = +1
Query: 247 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 393
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 394 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTS 573
L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS C +IAC +H+KY+S KS++
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSST 130
Query: 574 YVANGTQFAIQYGSGSLSGFLSTDDVTV-----------GGLKVRRQ 681
YV NGT F I YGSGSLSG+LS D V+V GG+KV RQ
Sbjct: 131 YVKNGTSFDIHYGSGSLSGYLSQDTVSVPCQSASSASALGGVKVERQ 177
>BT006910-1|AAP35556.1| 412|Homo sapiens cathepsin D (lysosomal
aspartyl protease) protein.
Length = 412
Score = 159 bits (385), Expect = 1e-38
Identities = 88/167 (52%), Positives = 105/167 (62%), Gaps = 22/167 (13%)
Frame = +1
Query: 247 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 393
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 394 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTS 573
L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS C +IAC +H+KY+S KS++
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSST 130
Query: 574 YVANGTQFAIQYGSGSLSGFLSTDDVTV-----------GGLKVRRQ 681
YV NGT F I YGSGSLSG+LS D V+V GG+KV RQ
Sbjct: 131 YVKNGTSFDIHYGSGSLSGYLSQDTVSVPCQSASSASALGGVKVERQ 177
>BC016320-1|AAH16320.1| 412|Homo sapiens cathepsin D protein.
Length = 412
Score = 159 bits (385), Expect = 1e-38
Identities = 88/167 (52%), Positives = 105/167 (62%), Gaps = 22/167 (13%)
Frame = +1
Query: 247 LALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRLKYDVT-----------GPSPEP 393
L L+A+ AL R+PLH+ + R EVG +E L K V+ GP PE
Sbjct: 11 LCLLAAPASALVRIPLHKFTSIRRTMSEVGGSVEDLIAKGPVSKYSQAVPAVTEGPIPEV 70
Query: 394 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTS 573
L NY+DAQYYG I IGTPPQ F VVFDTGSSNLWVPS C +IAC +H+KY+S KS++
Sbjct: 71 LKNYMDAQYYGEIGIGTPPQCFTVVFDTGSSNLWVPSIHCKLLDIACWIHHKYNSDKSST 130
Query: 574 YVANGTQFAIQYGSGSLSGFLSTDDVTV-----------GGLKVRRQ 681
YV NGT F I YGSGSLSG+LS D V+V GG+KV RQ
Sbjct: 131 YVKNGTSFDIHYGSGSLSGYLSQDTVSVPCQSASSASALGGVKVERQ 177
>BC017842-1|AAH17842.1| 420|Homo sapiens napsin A aspartic
peptidase protein.
Length = 420
Score = 147 bits (356), Expect = 4e-35
Identities = 69/143 (48%), Positives = 96/143 (67%), Gaps = 5/143 (3%)
Frame = +1
Query: 256 IASSVMALYRVPLHRMKTARTHFHEVG---TELELLRLKYDVTGPSP--EPLSNYLDAQY 420
+ S L R+PLHR++ R + + EL +L G P PLSNY D QY
Sbjct: 19 VEPSGATLIRIPLHRVQPGRRTLNLLRGWREPAELPKLGAPSPGDKPIFVPLSNYRDVQY 78
Query: 421 YGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQFA 600
+G I +GTPPQ+F V FDTGSSNLWVPS++CH+ ++ C LH+++D + S+S+ ANGT+FA
Sbjct: 79 FGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHHRFDPKASSSFQANGTKFA 138
Query: 601 IQYGSGSLSGFLSTDDVTVGGLK 669
IQYG+G + G LS D +T+GG+K
Sbjct: 139 IQYGTGRVDGILSEDKLTIGGIK 161
>AF200345-1|AAF17081.1| 420|Homo sapiens aspartyl protease 4
protein.
Length = 420
Score = 146 bits (355), Expect = 5e-35
Identities = 69/143 (48%), Positives = 96/143 (67%), Gaps = 5/143 (3%)
Frame = +1
Query: 256 IASSVMALYRVPLHRMKTARTHFHEVG---TELELLRLKYDVTGPSP--EPLSNYLDAQY 420
+ S L R+PLHR++ R + + EL +L G P PLSNY D QY
Sbjct: 19 VEPSGATLIRIPLHRVQPGRRILNLLRGWREPAELPKLGAPSPGDKPIFVPLSNYRDVQY 78
Query: 421 YGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQFA 600
+G I +GTPPQ+F V FDTGSSNLWVPS++CH+ ++ C LH+++D + S+S+ ANGT+FA
Sbjct: 79 FGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHHRFDPKASSSFQANGTKFA 138
Query: 601 IQYGSGSLSGFLSTDDVTVGGLK 669
IQYG+G + G LS D +T+GG+K
Sbjct: 139 IQYGTGRVDGILSEDKLTIGGIK 161
>AF098484-1|AAD13215.1| 420|Homo sapiens napsin 1 precursor
protein.
Length = 420
Score = 146 bits (355), Expect = 5e-35
Identities = 69/143 (48%), Positives = 96/143 (67%), Gaps = 5/143 (3%)
Frame = +1
Query: 256 IASSVMALYRVPLHRMKTARTHFHEVG---TELELLRLKYDVTGPSP--EPLSNYLDAQY 420
+ S L R+PLHR++ R + + EL +L G P PLSNY D QY
Sbjct: 19 VEPSGATLIRIPLHRVQPGRRILNLLRGWREPAELPKLGAPSPGDKPIFVPLSNYRDVQY 78
Query: 421 YGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQFA 600
+G I +GTPPQ+F V FDTGSSNLWVPS++CH+ ++ C LH+++D + S+S+ ANGT+FA
Sbjct: 79 FGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHHRFDPKASSSFQANGTKFA 138
Query: 601 IQYGSGSLSGFLSTDDVTVGGLK 669
IQYG+G + G LS D +T+GG+K
Sbjct: 139 IQYGTGRVDGILSEDKLTIGGIK 161
>AF090386-1|AAD04917.1| 420|Homo sapiens napsin A protein.
Length = 420
Score = 146 bits (355), Expect = 5e-35
Identities = 69/143 (48%), Positives = 96/143 (67%), Gaps = 5/143 (3%)
Frame = +1
Query: 256 IASSVMALYRVPLHRMKTARTHFHEVG---TELELLRLKYDVTGPSP--EPLSNYLDAQY 420
+ S L R+PLHR++ R + + EL +L G P PLSNY D QY
Sbjct: 19 VEPSGATLIRIPLHRVQPGRRILNLLRGWREPAELPKLGAPSPGDKPIFVPLSNYRDVQY 78
Query: 421 YGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQFA 600
+G I +GTPPQ+F V FDTGSSNLWVPS++CH+ ++ C LH+++D + S+S+ ANGT+FA
Sbjct: 79 FGEIGLGTPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWLHHRFDPKASSSFQANGTKFA 138
Query: 601 IQYGSGSLSGFLSTDDVTVGGLK 669
IQYG+G + G LS D +T+GG+K
Sbjct: 139 IQYGTGRVDGILSEDKLTIGGIK 161
>BC111705-1|AAI11706.1| 464|Homo sapiens NAPSB protein protein.
Length = 464
Score = 136 bits (329), Expect = 7e-32
Identities = 63/136 (46%), Positives = 91/136 (66%), Gaps = 5/136 (3%)
Frame = +1
Query: 277 LYRVPLHRMKTARTHFHEV---GTELELLRLKYDVTGPSPE--PLSNYLDAQYYGVISIG 441
L R+PL ++ R + + G EL +L G P PLS +LDAQY+G I +G
Sbjct: 22 LIRIPLRQVHPGRRTLNLLRGWGKPAELPKLGAPSPGDKPASVPLSKFLDAQYFGEIGLG 81
Query: 442 TPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQFAIQYGSGS 621
TPPQ+F V FDTGSSNLWVPS++CH+ ++ C H++++ S+S+ +GT+FAIQYG+G
Sbjct: 82 TPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWFHHRFNPNASSSFKPSGTKFAIQYGTGR 141
Query: 622 LSGFLSTDDVTVGGLK 669
+ G LS D +T+GG+K
Sbjct: 142 VDGILSEDKLTIGGIK 157
>AF200344-1|AAF17080.1| 450|Homo sapiens aspartyl protease 3
protein.
Length = 450
Score = 136 bits (329), Expect = 7e-32
Identities = 63/136 (46%), Positives = 91/136 (66%), Gaps = 5/136 (3%)
Frame = +1
Query: 277 LYRVPLHRMKTARTHFHEV---GTELELLRLKYDVTGPSPE--PLSNYLDAQYYGVISIG 441
L R+PL ++ R + + G EL +L G P PLS +LDAQY+G I +G
Sbjct: 26 LIRIPLRQVHPGRRTLNLLRGWGKPAELPKLGAPSPGDKPASVPLSKFLDAQYFGEIGLG 85
Query: 442 TPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQFAIQYGSGS 621
TPPQ+F V FDTGSSNLWVPS++CH+ ++ C H++++ S+S+ +GT+FAIQYG+G
Sbjct: 86 TPPQNFTVAFDTGSSNLWVPSRRCHFFSVPCWFHHRFNPNASSSFKPSGTKFAIQYGTGR 145
Query: 622 LSGFLSTDDVTVGGLK 669
+ G LS D +T+GG+K
Sbjct: 146 VDGILSEDKLTIGGIK 161
>M26901-1|AAA60364.1| 403|Homo sapiens renin protein.
Length = 403
Score = 128 bits (310), Expect = 1e-29
Identities = 55/93 (59%), Positives = 71/93 (76%)
Frame = +1
Query: 394 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTS 573
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S+S
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 574 YVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKV 672
Y NGT+ ++Y +G++SGFLS D +TVGG+ V
Sbjct: 138 YKHNGTELTLRYSTGTVSGFLSQDIITVGGITV 170
>M10152-1|AAD03461.1| 406|Homo sapiens renin protein.
Length = 406
Score = 128 bits (310), Expect = 1e-29
Identities = 55/93 (59%), Positives = 71/93 (76%)
Frame = +1
Query: 394 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTS 573
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S+S
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 574 YVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKV 672
Y NGT+ ++Y +G++SGFLS D +TVGG+ V
Sbjct: 138 YKHNGTELTLRYSTGTVSGFLSQDIITVGGITV 170
>L00073-1|AAA60363.1| 406|Homo sapiens renin protein.
Length = 406
Score = 128 bits (310), Expect = 1e-29
Identities = 55/93 (59%), Positives = 71/93 (76%)
Frame = +1
Query: 394 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTS 573
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S+S
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 574 YVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKV 672
Y NGT+ ++Y +G++SGFLS D +TVGG+ V
Sbjct: 138 YKHNGTELTLRYSTGTVSGFLSQDIITVGGITV 170
>CR536498-1|CAG38737.1| 406|Homo sapiens REN protein.
Length = 406
Score = 128 bits (310), Expect = 1e-29
Identities = 55/93 (59%), Positives = 71/93 (76%)
Frame = +1
Query: 394 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTS 573
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S+S
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 574 YVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKV 672
Y NGT+ ++Y +G++SGFLS D +TVGG+ V
Sbjct: 138 YKHNGTELTLRYSTGTVSGFLSQDIITVGGITV 170
>BC047752-1|AAH47752.1| 406|Homo sapiens renin protein.
Length = 406
Score = 128 bits (310), Expect = 1e-29
Identities = 55/93 (59%), Positives = 71/93 (76%)
Frame = +1
Query: 394 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTS 573
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S+S
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 574 YVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKV 672
Y NGT+ ++Y +G++SGFLS D +TVGG+ V
Sbjct: 138 YKHNGTELTLRYSTGTVSGFLSQDIITVGGITV 170
>BC033474-1|AAH33474.1| 406|Homo sapiens renin protein.
Length = 406
Score = 128 bits (310), Expect = 1e-29
Identities = 55/93 (59%), Positives = 71/93 (76%)
Frame = +1
Query: 394 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTS 573
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S+S
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 574 YVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKV 672
Y NGT+ ++Y +G++SGFLS D +TVGG+ V
Sbjct: 138 YKHNGTELTLRYSTGTVSGFLSQDIITVGGITV 170
>AY436324-1|AAR03502.1| 403|Homo sapiens renin protein.
Length = 403
Score = 128 bits (310), Expect = 1e-29
Identities = 55/93 (59%), Positives = 71/93 (76%)
Frame = +1
Query: 394 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTS 573
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S+S
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 574 YVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKV 672
Y NGT+ ++Y +G++SGFLS D +TVGG+ V
Sbjct: 138 YKHNGTELTLRYSTGTVSGFLSQDIITVGGITV 170
>AL592146-1|CAI16594.1| 406|Homo sapiens renin protein.
Length = 406
Score = 128 bits (310), Expect = 1e-29
Identities = 55/93 (59%), Positives = 71/93 (76%)
Frame = +1
Query: 394 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTS 573
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S+S
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 574 YVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKV 672
Y NGT+ ++Y +G++SGFLS D +TVGG+ V
Sbjct: 138 YKHNGTELTLRYSTGTVSGFLSQDIITVGGITV 170
>AL592114-1|CAH71224.1| 406|Homo sapiens renin protein.
Length = 406
Score = 128 bits (310), Expect = 1e-29
Identities = 55/93 (59%), Positives = 71/93 (76%)
Frame = +1
Query: 394 LSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTS 573
L+NY+D QYYG I IGTPPQ+FKVVFDTGSSN+WVPS KC AC+ H +D+ S+S
Sbjct: 78 LTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSS 137
Query: 574 YVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKV 672
Y NGT+ ++Y +G++SGFLS D +TVGG+ V
Sbjct: 138 YKHNGTELTLRYSTGTVSGFLSQDIITVGGITV 170
>J00287-1|AAA98529.1| 388|Homo sapiens PEP protein.
Length = 388
Score = 120 bits (288), Expect = 6e-27
Identities = 67/160 (41%), Positives = 91/160 (56%), Gaps = 12/160 (7%)
Frame = +1
Query: 238 LFFLALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRL-------KYDVTGPSP--- 387
L L L+A S +Y+VPL R K+ R E G + L+ KY +P
Sbjct: 4 LLLLGLVALSECIMYKVPLIRKKSLRRTLSERGLLKDFLKKHNLNPARKYFPQWEAPTLV 63
Query: 388 --EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSR 561
+PL NYLD +Y+G I IGTP Q F VVFDTGSSNLWVPS C +++AC HN+++
Sbjct: 64 DEQPLENYLDMEYFGTIGIGTPAQDFTVVFDTGSSNLWVPSVYC--SSLACTNHNRFNPE 121
Query: 562 KSTSYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQ 681
S++Y + +I YG+GS++G L D V VGG+ Q
Sbjct: 122 DSSTYQSTSETVSITYGTGSMTGILGYDTVQVGGISDTNQ 161
>BC029055-1|AAH29055.1| 388|Homo sapiens pepsinogen 5, group I
(pepsinogen A) protein.
Length = 388
Score = 120 bits (288), Expect = 6e-27
Identities = 67/160 (41%), Positives = 91/160 (56%), Gaps = 12/160 (7%)
Frame = +1
Query: 238 LFFLALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRL-------KYDVTGPSP--- 387
L L L+A S +Y+VPL R K+ R E G + L+ KY +P
Sbjct: 4 LLLLGLVALSECIMYKVPLIRKKSLRRTLSERGLLKDFLKKHNLNPARKYFPQWEAPTLV 63
Query: 388 --EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSR 561
+PL NYLD +Y+G I IGTP Q F VVFDTGSSNLWVPS C +++AC HN+++
Sbjct: 64 DEQPLENYLDMEYFGTIGIGTPAQDFTVVFDTGSSNLWVPSVYC--SSLACTNHNRFNPE 121
Query: 562 KSTSYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQ 681
S++Y + +I YG+GS++G L D V VGG+ Q
Sbjct: 122 DSSTYQSTSETVSITYGTGSMTGILGYDTVQVGGISDTNQ 161
>U75272-1|AAB18273.1| 388|Homo sapiens gastricsin protein.
Length = 388
Score = 119 bits (287), Expect = 8e-27
Identities = 66/145 (45%), Positives = 91/145 (62%), Gaps = 9/145 (6%)
Frame = +1
Query: 274 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 426
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 427 VISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQFAIQ 606
ISIGTPPQ+F V+FDTGSSNLWVPS C + AC H++++ +S++Y NG F++Q
Sbjct: 76 EISIGTPPQNFLVLFDTGSSNLWVPSVYCQ--SQACTSHSRFNPSESSTYSTNGQTFSLQ 133
Query: 607 YGSGSLSGFLSTDDVTVGGLKVRRQ 681
YGSGSL+GF D +TV ++V Q
Sbjct: 134 YGSGSLTGFFGYDTLTVQSIQVPNQ 158
>M84424-1|AAA52300.1| 396|Homo sapiens cathepsin E protein.
Length = 396
Score = 119 bits (287), Expect = 8e-27
Identities = 66/155 (42%), Positives = 93/155 (60%), Gaps = 10/155 (6%)
Frame = +1
Query: 238 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 387
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 388 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKS 567
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC H+++ +S
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQS 125
Query: 568 TSYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKV 672
++Y G F+IQYG+GSLSG + D V+V GL V
Sbjct: 126 STYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTV 160
>M23077-1|AAA60063.1| 388|Homo sapiens pepsinogen C protein.
Length = 388
Score = 119 bits (287), Expect = 8e-27
Identities = 66/145 (45%), Positives = 91/145 (62%), Gaps = 9/145 (6%)
Frame = +1
Query: 274 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 426
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 427 VISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQFAIQ 606
ISIGTPPQ+F V+FDTGSSNLWVPS C + AC H++++ +S++Y NG F++Q
Sbjct: 76 EISIGTPPQNFLVLFDTGSSNLWVPSVYCQ--SQACTSHSRFNPSESSTYSTNGQTFSLQ 133
Query: 607 YGSGSLSGFLSTDDVTVGGLKVRRQ 681
YGSGSL+GF D +TV ++V Q
Sbjct: 134 YGSGSLTGFFGYDTLTVQSIQVPNQ 158
>M18667-1|AAA60062.1| 385|Homo sapiens pepsinogen protein.
Length = 385
Score = 119 bits (287), Expect = 8e-27
Identities = 66/145 (45%), Positives = 91/145 (62%), Gaps = 9/145 (6%)
Frame = +1
Query: 274 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 426
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 14 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 72
Query: 427 VISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQFAIQ 606
ISIGTPPQ+F V+FDTGSSNLWVPS C + AC H++++ +S++Y NG F++Q
Sbjct: 73 EISIGTPPQNFLVLFDTGSSNLWVPSVYCQ--SQACTSHSRFNPSESSTYSTNGQTFSLQ 130
Query: 607 YGSGSLSGFLSTDDVTVGGLKVRRQ 681
YGSGSL+GF D +TV ++V Q
Sbjct: 131 YGSGSLTGFFGYDTLTVQSIQVPNQ 155
>J05036-1|AAA52130.1| 396|Homo sapiens CTSE protein.
Length = 396
Score = 119 bits (287), Expect = 8e-27
Identities = 66/155 (42%), Positives = 93/155 (60%), Gaps = 10/155 (6%)
Frame = +1
Query: 238 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 387
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 388 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKS 567
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC H+++ +S
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQS 125
Query: 568 TSYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKV 672
++Y G F+IQYG+GSLSG + D V+V GL V
Sbjct: 126 STYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTV 160
>J04443-1|AAA60074.1| 388|Homo sapiens pepsinogen protein.
Length = 388
Score = 119 bits (287), Expect = 8e-27
Identities = 66/145 (45%), Positives = 91/145 (62%), Gaps = 9/145 (6%)
Frame = +1
Query: 274 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 426
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 427 VISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQFAIQ 606
ISIGTPPQ+F V+FDTGSSNLWVPS C + AC H++++ +S++Y NG F++Q
Sbjct: 76 EISIGTPPQNFLVLFDTGSSNLWVPSVYCQ--SQACTSHSRFNPSESSTYSTNGQTFSLQ 133
Query: 607 YGSGSLSGFLSTDDVTVGGLKVRRQ 681
YGSGSL+GF D +TV ++V Q
Sbjct: 134 YGSGSLTGFFGYDTLTVQSIQVPNQ 158
>BX571818-5|CAH73265.1| 363|Homo sapiens cathepsin E protein.
Length = 363
Score = 119 bits (287), Expect = 8e-27
Identities = 66/155 (42%), Positives = 93/155 (60%), Gaps = 10/155 (6%)
Frame = +1
Query: 238 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 387
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 388 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKS 567
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC H+++ +S
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQS 125
Query: 568 TSYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKV 672
++Y G F+IQYG+GSLSG + D V+V GL V
Sbjct: 126 STYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTV 160
>BX571818-4|CAH73264.1| 396|Homo sapiens cathepsin E protein.
Length = 396
Score = 119 bits (287), Expect = 8e-27
Identities = 66/155 (42%), Positives = 93/155 (60%), Gaps = 10/155 (6%)
Frame = +1
Query: 238 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 387
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 388 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKS 567
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC H+++ +S
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQS 125
Query: 568 TSYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKV 672
++Y G F+IQYG+GSLSG + D V+V GL V
Sbjct: 126 STYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTV 160
>BC073740-1|AAH73740.1| 388|Homo sapiens progastricsin (pepsinogen
C) protein.
Length = 388
Score = 119 bits (287), Expect = 8e-27
Identities = 66/145 (45%), Positives = 91/145 (62%), Gaps = 9/145 (6%)
Frame = +1
Query: 274 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 426
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 427 VISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQFAIQ 606
ISIGTPPQ+F V+FDTGSSNLWVPS C + AC H++++ +S++Y NG F++Q
Sbjct: 76 EISIGTPPQNFLVLFDTGSSNLWVPSVYCQ--SQACTSHSRFNPSESSTYSTNGQTFSLQ 133
Query: 607 YGSGSLSGFLSTDDVTVGGLKVRRQ 681
YGSGSL+GF D +TV ++V Q
Sbjct: 134 YGSGSLTGFFGYDTLTVQSIQVPNQ 158
>BC042537-1|AAH42537.1| 396|Homo sapiens cathepsin E protein.
Length = 396
Score = 119 bits (287), Expect = 8e-27
Identities = 66/155 (42%), Positives = 93/155 (60%), Gaps = 10/155 (6%)
Frame = +1
Query: 238 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 387
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 388 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKS 567
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC H+++ +S
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQS 125
Query: 568 TSYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKV 672
++Y G F+IQYG+GSLSG + D V+V GL V
Sbjct: 126 STYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTV 160
>AL365205-1|CAI13181.1| 388|Homo sapiens progastricsin (pepsinogen
C) protein.
Length = 388
Score = 119 bits (287), Expect = 8e-27
Identities = 66/145 (45%), Positives = 91/145 (62%), Gaps = 9/145 (6%)
Frame = +1
Query: 274 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 426
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 427 VISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQFAIQ 606
ISIGTPPQ+F V+FDTGSSNLWVPS C + AC H++++ +S++Y NG F++Q
Sbjct: 76 EISIGTPPQNFLVLFDTGSSNLWVPSVYCQ--SQACTSHSRFNPSESSTYSTNGQTFSLQ 133
Query: 607 YGSGSLSGFLSTDDVTVGGLKVRRQ 681
YGSGSL+GF D +TV ++V Q
Sbjct: 134 YGSGSLTGFFGYDTLTVQSIQVPNQ 158
>AJ250717-1|CAB82850.1| 396|Homo sapiens procathepsin E protein.
Length = 396
Score = 119 bits (287), Expect = 8e-27
Identities = 66/155 (42%), Positives = 93/155 (60%), Gaps = 10/155 (6%)
Frame = +1
Query: 238 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 387
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 388 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKS 567
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC H+++ +S
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQS 125
Query: 568 TSYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKV 672
++Y G F+IQYG+GSLSG + D V+V GL V
Sbjct: 126 STYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTV 160
>AJ250716-1|CAB82849.1| 363|Homo sapiens cathepsin E, alternative
protein.
Length = 363
Score = 119 bits (287), Expect = 8e-27
Identities = 66/155 (42%), Positives = 93/155 (60%), Gaps = 10/155 (6%)
Frame = +1
Query: 238 LFFLALIASSVMALYRVPLHRMKT------ARTHFHEVGTELELLRLKY----DVTGPSP 387
L L + + +L+RVPL R + AR+ E L +++ + +
Sbjct: 8 LLVLLELGEAQGSLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDMIQFTESCSMDQSAK 67
Query: 388 EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKS 567
EPL NYLD +Y+G ISIG+PPQ+F V+FDTGSSNLWVPS C T+ AC H+++ +S
Sbjct: 68 EPLINYLDMEYFGTISIGSPPQNFTVIFDTGSSNLWVPSVYC--TSPACKTHSRFQPSQS 125
Query: 568 TSYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKV 672
++Y G F+IQYG+GSLSG + D V+V GL V
Sbjct: 126 STYSQPGQSFSIQYGTGSLSGIIGADQVSVEGLTV 160
>M26032-1|AAA60061.1| 388|Homo sapiens pepsinogen A protein.
Length = 388
Score = 118 bits (284), Expect = 2e-26
Identities = 66/160 (41%), Positives = 91/160 (56%), Gaps = 12/160 (7%)
Frame = +1
Query: 238 LFFLALIASSVMALYRVPLHRMKTARTHFHEVGTELELLRL-------KYDVTGPSP--- 387
L L L+A S +Y+VPL R K+ R E G + L+ KY +P
Sbjct: 4 LLLLGLVALSECIMYKVPLIRKKSFRRTLSERGLLKDFLKKHNLNPARKYFPQWKAPTLV 63
Query: 388 --EPLSNYLDAQYYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSR 561
+PL NYLD +Y+G I IGTP Q F V+FDTGSSNLWVPS C +++AC HN+++
Sbjct: 64 DEQPLENYLDMEYFGTIGIGTPAQDFTVLFDTGSSNLWVPSVYC--SSLACTNHNRFNPE 121
Query: 562 KSTSYVANGTQFAIQYGSGSLSGFLSTDDVTVGGLKVRRQ 681
S++Y + +I YG+GS++G L D V VGG+ Q
Sbjct: 122 DSSTYQSTSETVSITYGTGSMTGILGYDTVQVGGISDTNQ 161
>X00063-1|CAA24937.1| 300|Homo sapiens protein ( Human kidney mRNA
fragment for renin (aa 105-401). ).
Length = 300
Score = 74.9 bits (176), Expect = 2e-13
Identities = 31/63 (49%), Positives = 44/63 (69%)
Frame = +1
Query: 484 SNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQFAIQYGSGSLSGFLSTDDVTVGG 663
SN+WVPS KC AC+ H +D+ S+SY NGT+ ++Y +G++SGFLS D +TVGG
Sbjct: 1 SNVWVPSSKCSRLYTACVYHKLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGG 60
Query: 664 LKV 672
+ V
Sbjct: 61 ITV 63
>BC042578-1|AAH42578.1| 104|Homo sapiens PGC protein protein.
Length = 104
Score = 60.1 bits (139), Expect = 7e-09
Identities = 38/82 (46%), Positives = 49/82 (59%), Gaps = 9/82 (10%)
Frame = +1
Query: 274 ALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQYYG 426
A+ +VPL + K+ R E G E LR KYD + EP++ Y+DA Y+G
Sbjct: 17 AVVKVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAAYFG 75
Query: 427 VISIGTPPQSFKVVFDTGSSNL 492
ISIGTPPQ+F V+FDTGSS L
Sbjct: 76 EISIGTPPQNFLVLFDTGSSPL 97
>BC014453-1|AAH14453.1| 518|Homo sapiens beta-site APP-cleaving
enzyme 2 protein.
Length = 518
Score = 54.4 bits (125), Expect = 4e-07
Identities = 28/80 (35%), Positives = 44/80 (55%)
Frame = +1
Query: 418 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQF 597
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S++Y + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 598 AIQYGSGSLSGFLSTDDVTV 657
++Y GS +GF+ D VT+
Sbjct: 146 TVKYTQGSWTGFVGEDLVTI 165
>AY358927-1|AAQ89286.1| 518|Homo sapiens BACE2 protein.
Length = 518
Score = 54.4 bits (125), Expect = 4e-07
Identities = 28/80 (35%), Positives = 44/80 (55%)
Frame = +1
Query: 418 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQF 597
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S++Y + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 598 AIQYGSGSLSGFLSTDDVTV 657
++Y GS +GF+ D VT+
Sbjct: 146 TVKYTQGSWTGFVGEDLVTI 165
>AF212252-1|AAG41783.1| 439|Homo sapiens CDA13 protein.
Length = 439
Score = 54.4 bits (125), Expect = 4e-07
Identities = 28/80 (35%), Positives = 44/80 (55%)
Frame = +1
Query: 418 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQF 597
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S++Y + G
Sbjct: 13 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 66
Query: 598 AIQYGSGSLSGFLSTDDVTV 657
++Y GS +GF+ D VT+
Sbjct: 67 TVKYTQGSWTGFVGEDLVTI 86
>AF204944-1|AAF26368.1| 518|Homo sapiens transmembrane aspartic
proteinase Asp 1 protein.
Length = 518
Score = 54.4 bits (125), Expect = 4e-07
Identities = 28/80 (35%), Positives = 44/80 (55%)
Frame = +1
Query: 418 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQF 597
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S++Y + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 598 AIQYGSGSLSGFLSTDDVTV 657
++Y GS +GF+ D VT+
Sbjct: 146 TVKYTQGSWTGFVGEDLVTI 165
>AF200342-1|AAF17078.1| 518|Homo sapiens aspartyl protease 1
protein.
Length = 518
Score = 54.4 bits (125), Expect = 4e-07
Identities = 28/80 (35%), Positives = 44/80 (55%)
Frame = +1
Query: 418 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQF 597
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S++Y + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 598 AIQYGSGSLSGFLSTDDVTV 657
++Y GS +GF+ D VT+
Sbjct: 146 TVKYTQGSWTGFVGEDLVTI 165
>AF200192-1|AAF13714.1| 518|Homo sapiens memapsin 1 protein.
Length = 518
Score = 54.4 bits (125), Expect = 4e-07
Identities = 28/80 (35%), Positives = 44/80 (55%)
Frame = +1
Query: 418 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQF 597
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S++Y + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 598 AIQYGSGSLSGFLSTDDVTV 657
++Y GS +GF+ D VT+
Sbjct: 146 TVKYTQGSWTGFVGEDLVTI 165
>AF188277-1|AAF35836.1| 396|Homo sapiens aspartyl protease protein.
Length = 396
Score = 54.4 bits (125), Expect = 4e-07
Identities = 28/80 (35%), Positives = 44/80 (55%)
Frame = +1
Query: 418 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQF 597
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S++Y + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 598 AIQYGSGSLSGFLSTDDVTV 657
++Y GS +GF+ D VT+
Sbjct: 146 TVKYTQGSWTGFVGEDLVTI 165
>AF188276-1|AAF35835.1| 468|Homo sapiens aspartyl protease protein.
Length = 468
Score = 54.4 bits (125), Expect = 4e-07
Identities = 28/80 (35%), Positives = 44/80 (55%)
Frame = +1
Query: 418 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQF 597
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S++Y + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 598 AIQYGSGSLSGFLSTDDVTV 657
++Y GS +GF+ D VT+
Sbjct: 146 TVKYTQGSWTGFVGEDLVTI 165
>AF178532-1|AAF29494.1| 518|Homo sapiens aspartyl protease protein.
Length = 518
Score = 54.4 bits (125), Expect = 4e-07
Identities = 28/80 (35%), Positives = 44/80 (55%)
Frame = +1
Query: 418 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQF 597
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S++Y + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 598 AIQYGSGSLSGFLSTDDVTV 657
++Y GS +GF+ D VT+
Sbjct: 146 TVKYTQGSWTGFVGEDLVTI 165
>AF117892-1|AAD45240.1| 518|Homo sapiens aspartic-like protease
protein.
Length = 518
Score = 54.4 bits (125), Expect = 4e-07
Identities = 28/80 (35%), Positives = 44/80 (55%)
Frame = +1
Query: 418 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQF 597
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S++Y + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 598 AIQYGSGSLSGFLSTDDVTV 657
++Y GS +GF+ D VT+
Sbjct: 146 TVKYTQGSWTGFVGEDLVTI 165
>AF050171-1|AAD45963.1| 518|Homo sapiens aspartyl protease protein.
Length = 518
Score = 54.4 bits (125), Expect = 4e-07
Identities = 28/80 (35%), Positives = 44/80 (55%)
Frame = +1
Query: 418 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQF 597
YY + IGTPPQ +++ DTGSSN V Y + +D+ +S++Y + G
Sbjct: 92 YYLEMLIGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDV 145
Query: 598 AIQYGSGSLSGFLSTDDVTV 657
++Y GS +GF+ D VT+
Sbjct: 146 TVKYTQGSWTGFVGEDLVTI 165
>AK075539-1|BAC11682.1| 423|Homo sapiens protein ( Homo sapiens
cDNA PSEC0239 fis, clone OVARC1000363, highly similar to
Homo sapiens aspartyl protease mRNA. ).
Length = 423
Score = 51.6 bits (118), Expect = 3e-06
Identities = 26/74 (35%), Positives = 41/74 (55%)
Frame = +1
Query: 436 IGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQFAIQYGS 615
IGTPPQ +++ DTGSSN V Y + +D+ +S++Y + G ++Y
Sbjct: 3 IGTPPQKLQILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDVTVKYTQ 56
Query: 616 GSLSGFLSTDDVTV 657
GS +GF+ D VT+
Sbjct: 57 GSWTGFVGEDLVTI 70
>DQ007053-1|AAY16982.1| 501|Homo sapiens beta-site APP-cleaving
enzyme 1 protein.
Length = 501
Score = 42.3 bits (95), Expect = 0.002
Identities = 25/80 (31%), Positives = 40/80 (50%)
Frame = +1
Query: 418 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQF 597
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S++Y
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 598 AIQYGSGSLSGFLSTDDVTV 657
+ Y G G L TD V++
Sbjct: 129 YVPYTQGKWEGELGTDLVSI 148
>BC065492-1|AAH65492.1| 501|Homo sapiens beta-site APP-cleaving
enzyme 1 protein.
Length = 501
Score = 42.3 bits (95), Expect = 0.002
Identities = 25/80 (31%), Positives = 40/80 (50%)
Frame = +1
Query: 418 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQF 597
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S++Y
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 598 AIQYGSGSLSGFLSTDDVTV 657
+ Y G G L TD V++
Sbjct: 129 YVPYTQGKWEGELGTDLVSI 148
>AF338816-1|AAK38374.1| 476|Homo sapiens beta-site APP cleaving
enzyme type B protein.
Length = 476
Score = 42.3 bits (95), Expect = 0.002
Identities = 25/80 (31%), Positives = 40/80 (50%)
Frame = +1
Query: 418 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQF 597
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S++Y
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 598 AIQYGSGSLSGFLSTDDVTV 657
+ Y G G L TD V++
Sbjct: 129 YVPYTQGKWEGELGTDLVSI 148
>AF204943-1|AAF26367.1| 501|Homo sapiens transmembrane aspartic
proteinase Asp 2 protein.
Length = 501
Score = 42.3 bits (95), Expect = 0.002
Identities = 25/80 (31%), Positives = 40/80 (50%)
Frame = +1
Query: 418 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQF 597
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S++Y
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 598 AIQYGSGSLSGFLSTDDVTV 657
+ Y G G L TD V++
Sbjct: 129 YVPYTQGKWEGELGTDLVSI 148
>AF201468-1|AAF18982.1| 501|Homo sapiens APP beta-secretase
protein.
Length = 501
Score = 42.3 bits (95), Expect = 0.002
Identities = 25/80 (31%), Positives = 40/80 (50%)
Frame = +1
Query: 418 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQF 597
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S++Y
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 598 AIQYGSGSLSGFLSTDDVTV 657
+ Y G G L TD V++
Sbjct: 129 YVPYTQGKWEGELGTDLVSI 148
>AF200343-1|AAF17079.1| 501|Homo sapiens aspartyl protease 2
protein.
Length = 501
Score = 42.3 bits (95), Expect = 0.002
Identities = 25/80 (31%), Positives = 40/80 (50%)
Frame = +1
Query: 418 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQF 597
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S++Y
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 598 AIQYGSGSLSGFLSTDDVTV 657
+ Y G G L TD V++
Sbjct: 129 YVPYTQGKWEGELGTDLVSI 148
>AF200193-1|AAF13715.1| 488|Homo sapiens memapsin 2 protein.
Length = 488
Score = 42.3 bits (95), Expect = 0.002
Identities = 25/80 (31%), Positives = 40/80 (50%)
Frame = +1
Query: 418 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQF 597
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S++Y
Sbjct: 62 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 115
Query: 598 AIQYGSGSLSGFLSTDDVTV 657
+ Y G G L TD V++
Sbjct: 116 YVPYTQGKWEGELGTDLVSI 135
>AF190725-1|AAF04142.1| 501|Homo sapiens beta-site APP cleaving
enzyme protein.
Length = 501
Score = 42.3 bits (95), Expect = 0.002
Identities = 25/80 (31%), Positives = 40/80 (50%)
Frame = +1
Query: 418 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQF 597
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S++Y
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 598 AIQYGSGSLSGFLSTDDVTV 657
+ Y G G L TD V++
Sbjct: 129 YVPYTQGKWEGELGTDLVSI 148
>AB050436-1|BAB40931.1| 476|Homo sapiens beta-site APP cleaving
enzyme I-476 protein.
Length = 476
Score = 42.3 bits (95), Expect = 0.002
Identities = 25/80 (31%), Positives = 40/80 (50%)
Frame = +1
Query: 418 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQF 597
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S++Y
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 598 AIQYGSGSLSGFLSTDDVTV 657
+ Y G G L TD V++
Sbjct: 129 YVPYTQGKWEGELGTDLVSI 148
>AB032975-1|BAA86463.2| 532|Homo sapiens KIAA1149 protein protein.
Length = 532
Score = 42.3 bits (95), Expect = 0.002
Identities = 25/80 (31%), Positives = 40/80 (50%)
Frame = +1
Query: 418 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQF 597
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S++Y
Sbjct: 106 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 159
Query: 598 AIQYGSGSLSGFLSTDDVTV 657
+ Y G G L TD V++
Sbjct: 160 YVPYTQGKWEGELGTDLVSI 179
>AF338817-1|AAK38375.1| 457|Homo sapiens beta-site APP cleaving
enzyme type C protein.
Length = 457
Score = 40.7 bits (91), Expect = 0.005
Identities = 24/76 (31%), Positives = 37/76 (48%)
Frame = +1
Query: 418 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQF 597
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S++Y
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 598 AIQYGSGSLSGFLSTD 645
+ Y G G L TD
Sbjct: 129 YVPYTQGKWEGELGTD 144
>AB050438-1|BAB40933.1| 432|Homo sapiens beta-site APP cleaving
enzyme I-432 protein.
Length = 432
Score = 40.7 bits (91), Expect = 0.005
Identities = 24/76 (31%), Positives = 37/76 (48%)
Frame = +1
Query: 418 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQF 597
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S++Y
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 598 AIQYGSGSLSGFLSTD 645
+ Y G G L TD
Sbjct: 129 YVPYTQGKWEGELGTD 144
>AB050437-1|BAB40932.1| 457|Homo sapiens beta-site APP cleaving
enzyme I-457 protein.
Length = 457
Score = 40.7 bits (91), Expect = 0.005
Identities = 24/76 (31%), Positives = 37/76 (48%)
Frame = +1
Query: 418 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQF 597
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S++Y
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTYRDLRKGV 128
Query: 598 AIQYGSGSLSGFLSTD 645
+ Y G G L TD
Sbjct: 129 YVPYTQGKWEGELGTD 144
>BC036084-1|AAH36084.1| 501|Homo sapiens beta-site APP-cleaving
enzyme 1 protein.
Length = 501
Score = 39.9 bits (89), Expect = 0.008
Identities = 24/80 (30%), Positives = 39/80 (48%)
Frame = +1
Query: 418 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQF 597
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + ++Y
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLFSTYRDLRKGV 128
Query: 598 AIQYGSGSLSGFLSTDDVTV 657
+ Y G G L TD V++
Sbjct: 129 YVPYTQGKWEGELGTDLVSI 148
>AL365205-3|CAM16152.1| 86|Homo sapiens progastricsin (pepsinogen
C) protein.
Length = 86
Score = 38.7 bits (86), Expect = 0.019
Identities = 28/70 (40%), Positives = 37/70 (52%), Gaps = 9/70 (12%)
Frame = +1
Query: 265 SVMALYRVPLHRMKTARTHFHEVGTELELLRL-KYDVT--------GPSPEPLSNYLDAQ 417
+V+ RVPL + K+ R E G E LR KYD + EP++ Y+DA
Sbjct: 18 AVICKQRVPLKKFKSIRETMKEKGLLGEFLRTHKYDPAWKYRFGDLSVTYEPMA-YMDAA 76
Query: 418 YYGVISIGTP 447
Y+G ISIGTP
Sbjct: 77 YFGEISIGTP 86
>AL163285-1|CAB90554.1| 415|Homo sapiens beta-site APP-cleaving
enzyme 2, EC 3.4.23. protein.
Length = 415
Score = 37.9 bits (84), Expect = 0.033
Identities = 20/66 (30%), Positives = 35/66 (53%)
Frame = +1
Query: 460 KVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQFAIQYGSGSLSGFLS 639
+++ DTGSSN V Y + +D+ +S++Y + G ++Y GS +GF+
Sbjct: 3 QILVDTGSSNFAVAGTPHSY------IDTYFDTERSSTYRSKGFDVTVKYTQGSWTGFVG 56
Query: 640 TDDVTV 657
D VT+
Sbjct: 57 EDLVTI 62
>AB089958-1|BAC81826.1| 127|Homo sapiens beta-site APP cleaving
enzyme isoform I-127 protein.
Length = 127
Score = 35.5 bits (78), Expect = 0.18
Identities = 18/53 (33%), Positives = 30/53 (56%)
Frame = +1
Query: 418 YYGVISIGTPPQSFKVVFDTGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSY 576
YY +++G+PPQ+ ++ DTGSSN V + + LH Y + S++Y
Sbjct: 75 YYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPF------LHRYYQRQLSSTY 121
>BC030606-1|AAH30606.2| 514|Homo sapiens coiled-coil domain
containing 11 protein.
Length = 514
Score = 30.7 bits (66), Expect = 5.0
Identities = 12/26 (46%), Positives = 18/26 (69%)
Frame = -3
Query: 483 GSGVEYHLERLRRRADTDHSVVLSIK 406
G G E+HLER+RR ++++ SIK
Sbjct: 30 GQGAEHHLERIRRSHQKHNAILASIK 55
>BC104851-1|AAI04852.1| 147|Homo sapiens LOC283174 protein protein.
Length = 147
Score = 30.3 bits (65), Expect = 6.7
Identities = 18/66 (27%), Positives = 29/66 (43%)
Frame = +1
Query: 475 TGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQFAIQYGSGSLSGFLSTDDVT 654
T + LW + + C L N S+ TS++ G+ Q S S FL+ ++
Sbjct: 7 THNGRLWGAGVHLYLSRKQCALKNTSLSKFQTSHICKGSALQPQQASPGASSFLTCPELG 66
Query: 655 VGGLKV 672
V LK+
Sbjct: 67 VMYLKL 72
>BC101691-1|AAI01692.1| 147|Homo sapiens LOC283174 protein protein.
Length = 147
Score = 30.3 bits (65), Expect = 6.7
Identities = 18/66 (27%), Positives = 29/66 (43%)
Frame = +1
Query: 475 TGSSNLWVPSKKCHYTNIACLLHNKYDSRKSTSYVANGTQFAIQYGSGSLSGFLSTDDVT 654
T + LW + + C L N S+ TS++ G+ Q S S FL+ ++
Sbjct: 7 THNGRLWGAGVHLYLSRKQCALKNTSLSKFQTSHICKGSALQPQQASPGASSFLTCPELG 66
Query: 655 VGGLKV 672
V LK+
Sbjct: 67 VMYLKL 72
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 95,601,655
Number of Sequences: 237096
Number of extensions: 2074240
Number of successful extensions: 3927
Number of sequences better than 10.0: 72
Number of HSP's better than 10.0 without gapping: 3803
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3888
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 7783251346
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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