Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= bmmt8m09
(652 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X07994-1|CAA30801.1| 1927|Homo sapiens protein ( Human mRNA for ... 208 1e-53
M61850-1|AAA59504.1| 1927|Homo sapiens lactase phlorizinhydrolas... 208 1e-53
AY191611-1|AAP12677.1| 1003|Homo sapiens lactase-phlorizin hydro... 208 1e-53
AC011893-3|AAX88924.1| 1927|Homo sapiens unknown protein. 208 1e-53
BC101829-1|AAI01830.1| 469|Homo sapiens cytosolic beta-glucosid... 197 3e-50
AK222963-1|BAD96683.1| 469|Homo sapiens cytosolic beta-glucosid... 197 3e-50
AJ278964-1|CAC08178.1| 469|Homo sapiens cytosolic beta-glucosid... 197 3e-50
AF323990-1|AAL37305.1| 469|Homo sapiens cytosolic beta-glucosid... 197 3e-50
AB017913-1|BAB18741.1| 469|Homo sapiens cytosolic beta-glucosid... 197 3e-50
AF317840-1|AAG39217.1| 469|Homo sapiens cytosolic beta-glucosid... 196 7e-50
AY358729-1|AAQ89091.1| 567|Homo sapiens KPVW3022 protein. 185 1e-46
BC113653-1|AAI13654.1| 1044|Homo sapiens klotho beta protein. 174 2e-43
BC104871-1|AAI04872.1| 1044|Homo sapiens klotho beta protein. 174 2e-43
AB079373-1|BAC56857.1| 1044|Homo sapiens klotho beta like protei... 174 2e-43
Z92540-2|CAC94767.1| 273|Homo sapiens 179I15.1 (klotho) protein. 162 9e-40
AL161898-1|CAH71888.1| 1012|Homo sapiens klotho protein. 162 9e-40
AB009667-2|BAA24941.1| 549|Homo sapiens Klotho protein (KL) pro... 162 9e-40
AB009667-1|BAA24940.1| 1012|Homo sapiens Klotho protein (KL) pro... 162 9e-40
AB005142-1|BAA23382.1| 1012|Homo sapiens klotho protein. 162 9e-40
BC109377-1|AAI09378.1| 162|Homo sapiens GBA3 protein protein. 103 4e-22
BC029362-1|AAH29362.1| 162|Homo sapiens GBA3 protein protein. 103 4e-22
BC070188-1|AAH70188.1| 162|Homo sapiens GBA3 protein protein. 103 7e-22
Z84483-1|CAC94773.1| 739|Homo sapiens 46H23.1 (Klotho) protein. 72 2e-12
>X07994-1|CAA30801.1| 1927|Homo sapiens protein ( Human mRNA for
lactase-phlorizin hydrolase LPH (EC 3.2.1.23-62). ).
Length = 1927
Score = 208 bits (508), Expect = 1e-53
Identities = 89/190 (46%), Positives = 120/190 (63%)
Frame = +3
Query: 78 TFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWER 257
TF F +G +S++YQ+EGAW+ KG SIWD HT + D GD+ CDSYH +
Sbjct: 902 TFRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYHQLDA 961
Query: 258 DIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFHW 437
D+ M L + YRFS+SW R+ PTG ++ I+ G YYN LI+GL+ I P+VT+FHW
Sbjct: 962 DLNMLRALKVKAYRFSISWSRIFPTGRNSSINSHGVDYYNRLINGLVASNIFPMVTLFHW 1021
Query: 438 DLPQSLQDLGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEPVSICDYVYNTGGMAP 617
DLPQ+LQD+GGW NP ++D F+ YA F F DRVK W++ NEP+ + Y +G P
Sbjct: 1022 DLPQALQDIGGWENPALIDLFDSYADFCFQTFGDRVKFWMTFNEPMYLAWLGYGSGEFPP 1081
Query: 618 PIFXPHVAPY 647
+ P APY
Sbjct: 1082 GVKDPGWAPY 1091
Score = 196 bits (479), Expect = 4e-50
Identities = 94/191 (49%), Positives = 119/191 (62%), Gaps = 1/191 (0%)
Frame = +3
Query: 81 FPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWERD 260
FP GF + AASA+YQ+EGAW KG SIWD HT P + + GDV CDSYH D
Sbjct: 1377 FPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSHT-PLRVENDAIGDVACDSYHKIAED 1435
Query: 261 IEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFHWD 440
+ LG+ YRFS+SW R++P G + I+E G YY LID LL I+P VTI+HWD
Sbjct: 1436 LVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLAASIQPQVTIYHWD 1495
Query: 441 LPQSLQDLGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEPVSICDYVYNTGGMAPP 620
LPQ+LQD+GGW N IV F++YA V+F D+VK W+++NEP I Y G AP
Sbjct: 1496 LPQTLQDVGGWENETIVQRFKEYADVLFQRLGDKVKFWITLNEPFVIAYQGYGYGTAAPG 1555
Query: 621 IF-XPHVAPYV 650
+ P APY+
Sbjct: 1556 VSNRPGTAPYI 1566
Score = 174 bits (424), Expect = 2e-43
Identities = 88/194 (45%), Positives = 111/194 (57%), Gaps = 4/194 (2%)
Frame = +3
Query: 78 TFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNG----DVTCDSYH 245
TFP GF +GA++ ++ VEG W +G SIWD P ++ T G +V DSYH
Sbjct: 381 TFPEGFLWGASTGAFNVEGGWAEGGRGVSIWD------PRRPLNTTEGQATLEVASDSYH 434
Query: 246 LWERDIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVT 425
D+ + L Y+FS+SW R+ P G + S G YYN LID L D GIEP+ T
Sbjct: 435 KVASDVALLCGLRAQVYKFSISWSRIFPMGHGSSPSLPGVAYYNKLIDRLQDAGIEPMAT 494
Query: 426 IFHWDLPQSLQDLGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEPVSICDYVYNTG 605
+FHWDLPQ+LQD GGW N +VD F DYA FS F DRVK WV+ +EP + Y TG
Sbjct: 495 LFHWDLPQALQDHGGWQNESVVDAFLDYAAFCFSTFGDRVKLWVTFHEPWVMSYAGYGTG 554
Query: 606 GMAPPIFXPHVAPY 647
P I P VA +
Sbjct: 555 QHPPGISDPGVASF 568
Score = 49.2 bits (112), Expect = 1e-05
Identities = 27/92 (29%), Positives = 40/92 (43%)
Frame = +3
Query: 294 YRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFHWDLPQSLQDLGGW 473
Y+ LSW +L+P G + E + Y L+ L ++P+V + H LP S
Sbjct: 87 YKVFLSWAQLLPAGSTQNPDEKTVQCYRRLLKALKTARLQPMVILHHQTLPASTLR---- 142
Query: 474 MNPLIVDWFEDYARVVFSLFADRVKTWVSINE 569
D F DYA F F D V W + ++
Sbjct: 143 RTEAFADLFADYATFAFHSFGDLVGIWFTFSD 174
>M61850-1|AAA59504.1| 1927|Homo sapiens lactase phlorizinhydrolase
protein.
Length = 1927
Score = 208 bits (508), Expect = 1e-53
Identities = 89/190 (46%), Positives = 120/190 (63%)
Frame = +3
Query: 78 TFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWER 257
TF F +G +S++YQ+EGAW+ KG SIWD HT + D GD+ CDSYH +
Sbjct: 902 TFRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYHQLDA 961
Query: 258 DIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFHW 437
D+ M L + YRFS+SW R+ PTG ++ I+ G YYN LI+GL+ I P+VT+FHW
Sbjct: 962 DLNMLRALKVKAYRFSISWSRIFPTGRNSSINSHGVDYYNRLINGLVASNIFPMVTLFHW 1021
Query: 438 DLPQSLQDLGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEPVSICDYVYNTGGMAP 617
DLPQ+LQD+GGW NP ++D F+ YA F F DRVK W++ NEP+ + Y +G P
Sbjct: 1022 DLPQALQDIGGWENPALIDLFDSYADFCFQTFGDRVKFWMTFNEPMYLAWLGYGSGEFPP 1081
Query: 618 PIFXPHVAPY 647
+ P APY
Sbjct: 1082 GVKDPGWAPY 1091
Score = 196 bits (479), Expect = 4e-50
Identities = 94/191 (49%), Positives = 119/191 (62%), Gaps = 1/191 (0%)
Frame = +3
Query: 81 FPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWERD 260
FP GF + AASA+YQ+EGAW KG SIWD HT P + + GDV CDSYH D
Sbjct: 1377 FPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSHT-PLRVENDAIGDVACDSYHKIAED 1435
Query: 261 IEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFHWD 440
+ LG+ YRFS+SW R++P G + I+E G YY LID LL I+P VTI+HWD
Sbjct: 1436 LVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLAASIQPQVTIYHWD 1495
Query: 441 LPQSLQDLGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEPVSICDYVYNTGGMAPP 620
LPQ+LQD+GGW N IV F++YA V+F D+VK W+++NEP I Y G AP
Sbjct: 1496 LPQTLQDVGGWENETIVQRFKEYADVLFQRLGDKVKFWITLNEPFVIAYQGYGYGTAAPG 1555
Query: 621 IF-XPHVAPYV 650
+ P APY+
Sbjct: 1556 VSNRPGTAPYI 1566
Score = 174 bits (424), Expect = 2e-43
Identities = 88/194 (45%), Positives = 111/194 (57%), Gaps = 4/194 (2%)
Frame = +3
Query: 78 TFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNG----DVTCDSYH 245
TFP GF +GA++ ++ VEG W +G SIWD P ++ T G +V DSYH
Sbjct: 381 TFPEGFLWGASTGAFNVEGGWAEGGRGVSIWD------PRRPLNTTEGQATLEVASDSYH 434
Query: 246 LWERDIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVT 425
D+ + L Y+FS+SW R+ P G + S G YYN LID L D GIEP+ T
Sbjct: 435 KVASDVALLCGLRAQVYKFSISWSRIFPMGHGSSPSLPGVAYYNKLIDRLQDAGIEPMAT 494
Query: 426 IFHWDLPQSLQDLGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEPVSICDYVYNTG 605
+FHWDLPQ+LQD GGW N +VD F DYA FS F DRVK WV+ +EP + Y TG
Sbjct: 495 LFHWDLPQALQDHGGWQNESVVDAFLDYAAFCFSTFGDRVKLWVTFHEPWVMSYAGYGTG 554
Query: 606 GMAPPIFXPHVAPY 647
P I P VA +
Sbjct: 555 QHPPGISDPGVASF 568
Score = 49.2 bits (112), Expect = 1e-05
Identities = 27/92 (29%), Positives = 40/92 (43%)
Frame = +3
Query: 294 YRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFHWDLPQSLQDLGGW 473
Y+ LSW +L+P G + E + Y L+ L ++P+V + H LP S
Sbjct: 87 YKVFLSWAQLLPAGSTQNPDEKTVQCYRRLLKALKTARLQPMVILHHQTLPASTLR---- 142
Query: 474 MNPLIVDWFEDYARVVFSLFADRVKTWVSINE 569
D F DYA F F D V W + ++
Sbjct: 143 RTEAFADLFADYATFAFHSFGDLVGIWFTFSD 174
>AY191611-1|AAP12677.1| 1003|Homo sapiens lactase-phlorizin
hydrolase-1 protein.
Length = 1003
Score = 208 bits (508), Expect = 1e-53
Identities = 89/190 (46%), Positives = 120/190 (63%)
Frame = +3
Query: 78 TFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWER 257
TF F +G +S++YQ+EGAW+ KG SIWD HT + D GD+ CDSYH +
Sbjct: 334 TFRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYHQLDA 393
Query: 258 DIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFHW 437
D+ M L + YRFS+SW R+ PTG ++ I+ G YYN LI+GL+ I P+VT+FHW
Sbjct: 394 DLNMLRALKVKAYRFSISWSRIFPTGRNSSINSHGVDYYNRLINGLVASNIFPMVTLFHW 453
Query: 438 DLPQSLQDLGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEPVSICDYVYNTGGMAP 617
DLPQ+LQD+GGW NP ++D F+ YA F F DRVK W++ NEP+ + Y +G P
Sbjct: 454 DLPQALQDIGGWENPALIDLFDSYADFCFQTFGDRVKFWMTFNEPMYLAWLGYGSGEFPP 513
Query: 618 PIFXPHVAPY 647
+ P APY
Sbjct: 514 GVKDPGWAPY 523
Score = 191 bits (466), Expect = 2e-48
Identities = 90/179 (50%), Positives = 113/179 (63%)
Frame = +3
Query: 81 FPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWERD 260
FP GF + AASA+YQ+EGAW KG SIWD HT P + + GDV CDSYH D
Sbjct: 809 FPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSHT-PLRVENDAIGDVACDSYHKIAED 867
Query: 261 IEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFHWD 440
+ LG+ YRFS+SW R++P G + I+E G YY LID LL I+P VTI+HWD
Sbjct: 868 LVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLAASIQPQVTIYHWD 927
Query: 441 LPQSLQDLGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEPVSICDYVYNTGGMAP 617
LPQ+LQD+GGW N IV F++YA V+F D+VK W+++NEP I Y G AP
Sbjct: 928 LPQTLQDVGGWENETIVQRFKEYADVLFQRLGDKVKFWITLNEPFVIAYQGYGYGTAAP 986
>AC011893-3|AAX88924.1| 1927|Homo sapiens unknown protein.
Length = 1927
Score = 208 bits (508), Expect = 1e-53
Identities = 89/190 (46%), Positives = 120/190 (63%)
Frame = +3
Query: 78 TFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWER 257
TF F +G +S++YQ+EGAW+ KG SIWD HT + D GD+ CDSYH +
Sbjct: 902 TFRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYHQLDA 961
Query: 258 DIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFHW 437
D+ M L + YRFS+SW R+ PTG ++ I+ G YYN LI+GL+ I P+VT+FHW
Sbjct: 962 DLNMLRALKVKAYRFSISWSRIFPTGRNSSINSHGVDYYNRLINGLVASNIFPMVTLFHW 1021
Query: 438 DLPQSLQDLGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEPVSICDYVYNTGGMAP 617
DLPQ+LQD+GGW NP ++D F+ YA F F DRVK W++ NEP+ + Y +G P
Sbjct: 1022 DLPQALQDIGGWENPALIDLFDSYADFCFQTFGDRVKFWMTFNEPMYLAWLGYGSGEFPP 1081
Query: 618 PIFXPHVAPY 647
+ P APY
Sbjct: 1082 GVKDPGWAPY 1091
Score = 196 bits (479), Expect = 4e-50
Identities = 94/191 (49%), Positives = 119/191 (62%), Gaps = 1/191 (0%)
Frame = +3
Query: 81 FPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWERD 260
FP GF + AASA+YQ+EGAW KG SIWD HT P + + GDV CDSYH D
Sbjct: 1377 FPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSHT-PLRVENDAIGDVACDSYHKIAED 1435
Query: 261 IEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFHWD 440
+ LG+ YRFS+SW R++P G + I+E G YY LID LL I+P VTI+HWD
Sbjct: 1436 LVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLAASIQPQVTIYHWD 1495
Query: 441 LPQSLQDLGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEPVSICDYVYNTGGMAPP 620
LPQ+LQD+GGW N IV F++YA V+F D+VK W+++NEP I Y G AP
Sbjct: 1496 LPQTLQDVGGWENETIVQRFKEYADVLFQRLGDKVKFWITLNEPFVIAYQGYGYGTAAPG 1555
Query: 621 IF-XPHVAPYV 650
+ P APY+
Sbjct: 1556 VSNRPGTAPYI 1566
Score = 174 bits (424), Expect = 2e-43
Identities = 88/194 (45%), Positives = 111/194 (57%), Gaps = 4/194 (2%)
Frame = +3
Query: 78 TFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNG----DVTCDSYH 245
TFP GF +GA++ ++ VEG W +G SIWD P ++ T G +V DSYH
Sbjct: 381 TFPEGFLWGASTGAFNVEGGWAEGGRGVSIWD------PRRPLNTTEGQATLEVASDSYH 434
Query: 246 LWERDIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVT 425
D+ + L Y+FS+SW R+ P G + S G YYN LID L D GIEP+ T
Sbjct: 435 KVASDVALLCGLRAQVYKFSISWSRIFPMGHGSSPSLPGVAYYNKLIDRLQDAGIEPMAT 494
Query: 426 IFHWDLPQSLQDLGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEPVSICDYVYNTG 605
+FHWDLPQ+LQD GGW N +VD F DYA FS F DRVK WV+ +EP + Y TG
Sbjct: 495 LFHWDLPQALQDHGGWQNESVVDAFLDYAAFCFSTFGDRVKLWVTFHEPWVMSYAGYGTG 554
Query: 606 GMAPPIFXPHVAPY 647
P I P VA +
Sbjct: 555 QHPPGISDPGVASF 568
Score = 49.2 bits (112), Expect = 1e-05
Identities = 27/92 (29%), Positives = 40/92 (43%)
Frame = +3
Query: 294 YRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFHWDLPQSLQDLGGW 473
Y+ LSW +L+P G + E + Y L+ L ++P+V + H LP S
Sbjct: 87 YKVFLSWAQLLPAGSTQNPDEKTVQCYRRLLKALKTARLQPMVILHHQTLPASTLR---- 142
Query: 474 MNPLIVDWFEDYARVVFSLFADRVKTWVSINE 569
D F DYA F F D V W + ++
Sbjct: 143 RTEAFADLFADYATFAFHSFGDLVGIWFTFSD 174
>BC101829-1|AAI01830.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 197 bits (480), Expect = 3e-50
Identities = 87/187 (46%), Positives = 119/187 (63%)
Frame = +3
Query: 75 LTFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWE 254
+ FP GF + AA+A+YQVEG W+ KG +WD H E + GDV C SY LWE
Sbjct: 1 MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWE 60
Query: 255 RDIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFH 434
D++ +LGL YRFSLSW RL+P G + I++ G YYN +ID LL G+ P+VT++H
Sbjct: 61 EDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYH 120
Query: 435 WDLPQSLQDLGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEPVSICDYVYNTGGMA 614
+DLPQ+L+D GGW++ I++ F+ YA+ FS F DRVK W++INE + Y+ G
Sbjct: 121 FDLPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFP 180
Query: 615 PPIFXPH 635
P I PH
Sbjct: 181 PGI--PH 185
>AK222963-1|BAD96683.1| 469|Homo sapiens cytosolic beta-glucosidase
variant protein.
Length = 469
Score = 197 bits (480), Expect = 3e-50
Identities = 87/187 (46%), Positives = 119/187 (63%)
Frame = +3
Query: 75 LTFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWE 254
+ FP GF + AA+A+YQVEG W+ KG +WD H E + GDV C SY LWE
Sbjct: 1 MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWE 60
Query: 255 RDIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFH 434
D++ +LGL YRFSLSW RL+P G + I++ G YYN +ID LL G+ P+VT++H
Sbjct: 61 EDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYH 120
Query: 435 WDLPQSLQDLGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEPVSICDYVYNTGGMA 614
+DLPQ+L+D GGW++ I++ F+ YA+ FS F DRVK W++INE + Y+ G
Sbjct: 121 FDLPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFP 180
Query: 615 PPIFXPH 635
P I PH
Sbjct: 181 PGI--PH 185
>AJ278964-1|CAC08178.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 197 bits (480), Expect = 3e-50
Identities = 87/187 (46%), Positives = 119/187 (63%)
Frame = +3
Query: 75 LTFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWE 254
+ FP GF + AA+A+YQVEG W+ KG +WD H E + GDV C SY LWE
Sbjct: 1 MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWE 60
Query: 255 RDIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFH 434
D++ +LGL YRFSLSW RL+P G + I++ G YYN +ID LL G+ P+VT++H
Sbjct: 61 EDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYH 120
Query: 435 WDLPQSLQDLGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEPVSICDYVYNTGGMA 614
+DLPQ+L+D GGW++ I++ F+ YA+ FS F DRVK W++INE + Y+ G
Sbjct: 121 FDLPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFP 180
Query: 615 PPIFXPH 635
P I PH
Sbjct: 181 PGI--PH 185
>AF323990-1|AAL37305.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 197 bits (480), Expect = 3e-50
Identities = 87/187 (46%), Positives = 119/187 (63%)
Frame = +3
Query: 75 LTFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWE 254
+ FP GF + AA+A+YQVEG W+ KG +WD H E + GDV C SY LWE
Sbjct: 1 MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWE 60
Query: 255 RDIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFH 434
D++ +LGL YRFSLSW RL+P G + I++ G YYN +ID LL G+ P+VT++H
Sbjct: 61 EDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYH 120
Query: 435 WDLPQSLQDLGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEPVSICDYVYNTGGMA 614
+DLPQ+L+D GGW++ I++ F+ YA+ FS F DRVK W++INE + Y+ G
Sbjct: 121 FDLPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFP 180
Query: 615 PPIFXPH 635
P I PH
Sbjct: 181 PGI--PH 185
>AB017913-1|BAB18741.1| 469|Homo sapiens cytosolic
beta-glucosidase-like protein-1 protein.
Length = 469
Score = 197 bits (480), Expect = 3e-50
Identities = 87/187 (46%), Positives = 119/187 (63%)
Frame = +3
Query: 75 LTFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWE 254
+ FP GF + AA+A+YQVEG W+ KG +WD H E + GDV C SY LWE
Sbjct: 1 MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWE 60
Query: 255 RDIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFH 434
D++ +LGL YRFSLSW RL+P G + I++ G YYN +ID LL G+ P+VT++H
Sbjct: 61 EDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYH 120
Query: 435 WDLPQSLQDLGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEPVSICDYVYNTGGMA 614
+DLPQ+L+D GGW++ I++ F+ YA+ FS F DRVK W++INE + Y+ G
Sbjct: 121 FDLPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFP 180
Query: 615 PPIFXPH 635
P I PH
Sbjct: 181 PGI--PH 185
>AF317840-1|AAG39217.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 196 bits (477), Expect = 7e-50
Identities = 87/187 (46%), Positives = 118/187 (63%)
Frame = +3
Query: 75 LTFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWE 254
+ FP GF + AA+A+YQVEG W+ KG +WD H E + GDV C SY LWE
Sbjct: 1 MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWE 60
Query: 255 RDIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFH 434
D++ +LGL YRFSLSW RL+P G + I++ G YYN +ID LL G+ P+VT++H
Sbjct: 61 EDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYH 120
Query: 435 WDLPQSLQDLGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEPVSICDYVYNTGGMA 614
+DLPQ+L+D GGW + I++ F+ YA+ FS F DRVK W++INE + Y+ G
Sbjct: 121 FDLPQTLEDQGGWWSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFP 180
Query: 615 PPIFXPH 635
P I PH
Sbjct: 181 PGI--PH 185
>AY358729-1|AAQ89091.1| 567|Homo sapiens KPVW3022 protein.
Length = 567
Score = 185 bits (451), Expect = 1e-46
Identities = 82/182 (45%), Positives = 117/182 (64%), Gaps = 2/182 (1%)
Frame = +3
Query: 78 TFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWER 257
TFP GF +G S++YQ EGAW+ KG SIWD H+ ++ DV CD Y+ +
Sbjct: 36 TFPLGFSWGVGSSAYQTEGAWDQDGKGPSIWDVFTHSGKGKVLGNETADVACDGYYKVQE 95
Query: 258 DIEMATELGLHFYRFSLSWPRLMPTGF-SNKISEDGQKYYNNLIDGLLDKGIEPLVTIFH 434
DI + EL ++ YRFSLSWPRL+PTG + ++++ G ++Y++LID LL I P+VT+ H
Sbjct: 96 DIILLRELHVNHYRFSLSWPRLLPTGIRAEQVNKKGIEFYSDLIDALLSSNITPIVTLHH 155
Query: 435 WDLPQSLQ-DLGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEPVSICDYVYNTGGM 611
WDLPQ LQ GGW N + ++F DYA + F F DRVK W++ ++P ++ + Y TG
Sbjct: 156 WDLPQLLQVKYGGWQNVSMANYFRDYANLCFEAFGDRVKHWITFSDPRAMAEKGYETGHH 215
Query: 612 AP 617
AP
Sbjct: 216 AP 217
>BC113653-1|AAI13654.1| 1044|Homo sapiens klotho beta protein.
Length = 1044
Score = 174 bits (424), Expect = 2e-43
Identities = 80/181 (44%), Positives = 112/181 (61%), Gaps = 1/181 (0%)
Frame = +3
Query: 78 TFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWER 257
TFP F +G + + QVEG+W KG SIWD +HT + + TNG + DSY E+
Sbjct: 80 TFPKNFFWGIGTGALQVEGSWKKDGKGPSIWDHFIHTHLKNVSS-TNG--SSDSYIFLEK 136
Query: 258 DIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFHW 437
D+ +G+ FY+FS+SWPRL P G + G +YY+ L+D L+ + IEP+VT++HW
Sbjct: 137 DLSALDFIGVSFYQFSISWPRLFPDGIVTVANAKGLQYYSTLLDALVLRNIEPIVTLYHW 196
Query: 438 DLPQSLQD-LGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEPVSICDYVYNTGGMA 614
DLP +LQ+ GGW N I+D F DYA F +F DRVK W++I+ P + + Y TG A
Sbjct: 197 DLPLALQEKYGGWKNDTIIDIFNDYATYCFQMFGDRVKYWITIHNPYLVAWHGYGTGMHA 256
Query: 615 P 617
P
Sbjct: 257 P 257
Score = 90.2 bits (214), Expect = 5e-18
Identities = 55/188 (29%), Positives = 91/188 (48%), Gaps = 12/188 (6%)
Frame = +3
Query: 81 FPPGFKFGAASASYQVEGAWN---VSDKGESIWD----RLVHTKPEAIMDLTNGDVTCDS 239
FP F +G + + E + SD +W+ RL+H + E + L C
Sbjct: 521 FPCDFSWGVTESVLKPESVASSPQFSDPHLYVWNATGNRLLH-RVEGVR-LKTRPAQCTD 578
Query: 240 YHLWERDIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPL 419
+ ++ +EM + + YRF+L W ++PTG + ++ +YY ++ L GI +
Sbjct: 579 FVNIKKQLEMLARMKVTHYRFALDWASVLPTGNLSAVNRQALRYYRCVVSEGLKLGISAM 638
Query: 420 VTIF-----HWDLPQSLQDLGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEPVSIC 584
VT++ H LP+ L GW+NP + F+ YA + F D VK W++INEP +
Sbjct: 639 VTLYYPTHAHLGLPEPLLHADGWLNPSTAEAFQAYAGLCFQELGDLVKLWITINEPNRLS 698
Query: 585 DYVYNTGG 608
D +YN G
Sbjct: 699 D-IYNRSG 705
>BC104871-1|AAI04872.1| 1044|Homo sapiens klotho beta protein.
Length = 1044
Score = 174 bits (424), Expect = 2e-43
Identities = 80/181 (44%), Positives = 112/181 (61%), Gaps = 1/181 (0%)
Frame = +3
Query: 78 TFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWER 257
TFP F +G + + QVEG+W KG SIWD +HT + + TNG + DSY E+
Sbjct: 80 TFPKNFFWGIGTGALQVEGSWKKDGKGPSIWDHFIHTHLKNVSS-TNG--SSDSYIFLEK 136
Query: 258 DIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFHW 437
D+ +G+ FY+FS+SWPRL P G + G +YY+ L+D L+ + IEP+VT++HW
Sbjct: 137 DLSALDFIGVSFYQFSISWPRLFPDGIVTVANAKGLQYYSTLLDALVLRNIEPIVTLYHW 196
Query: 438 DLPQSLQD-LGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEPVSICDYVYNTGGMA 614
DLP +LQ+ GGW N I+D F DYA F +F DRVK W++I+ P + + Y TG A
Sbjct: 197 DLPLALQEKYGGWKNDTIIDIFNDYATYCFQMFGDRVKYWITIHNPYLVAWHGYGTGMHA 256
Query: 615 P 617
P
Sbjct: 257 P 257
Score = 90.2 bits (214), Expect = 5e-18
Identities = 55/188 (29%), Positives = 91/188 (48%), Gaps = 12/188 (6%)
Frame = +3
Query: 81 FPPGFKFGAASASYQVEGAWN---VSDKGESIWD----RLVHTKPEAIMDLTNGDVTCDS 239
FP F +G + + E + SD +W+ RL+H + E + L C
Sbjct: 521 FPCDFSWGVTESVLKPESVASSPQFSDPHLYVWNATGNRLLH-RVEGVR-LKTRPAQCTD 578
Query: 240 YHLWERDIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPL 419
+ ++ +EM + + YRF+L W ++PTG + ++ +YY ++ L GI +
Sbjct: 579 FVNIKKQLEMLARMKVTHYRFALDWASVLPTGNLSAVNRQALRYYRCVVSEGLKLGISAM 638
Query: 420 VTIF-----HWDLPQSLQDLGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEPVSIC 584
VT++ H LP+ L GW+NP + F+ YA + F D VK W++INEP +
Sbjct: 639 VTLYYPTHAHLGLPEPLLHADGWLNPSTAEAFQAYAGLCFQELGDLVKLWITINEPNRLS 698
Query: 585 DYVYNTGG 608
D +YN G
Sbjct: 699 D-IYNRSG 705
>AB079373-1|BAC56857.1| 1044|Homo sapiens klotho beta like protein
protein.
Length = 1044
Score = 174 bits (424), Expect = 2e-43
Identities = 80/181 (44%), Positives = 112/181 (61%), Gaps = 1/181 (0%)
Frame = +3
Query: 78 TFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWER 257
TFP F +G + + QVEG+W KG SIWD +HT + + TNG + DSY E+
Sbjct: 80 TFPKNFFWGIGTGALQVEGSWKKDGKGPSIWDHFIHTHLKNVSS-TNG--SSDSYIFLEK 136
Query: 258 DIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFHW 437
D+ +G+ FY+FS+SWPRL P G + G +YY+ L+D L+ + IEP+VT++HW
Sbjct: 137 DLSALDFIGVSFYQFSISWPRLFPDGIVTVANAKGLQYYSTLLDALVLRNIEPIVTLYHW 196
Query: 438 DLPQSLQD-LGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEPVSICDYVYNTGGMA 614
DLP +LQ+ GGW N I+D F DYA F +F DRVK W++I+ P + + Y TG A
Sbjct: 197 DLPLALQEKYGGWKNDTIIDIFNDYATYCFQMFGDRVKYWITIHNPYLVAWHGYGTGMHA 256
Query: 615 P 617
P
Sbjct: 257 P 257
Score = 90.2 bits (214), Expect = 5e-18
Identities = 55/188 (29%), Positives = 91/188 (48%), Gaps = 12/188 (6%)
Frame = +3
Query: 81 FPPGFKFGAASASYQVEGAWN---VSDKGESIWD----RLVHTKPEAIMDLTNGDVTCDS 239
FP F +G + + E + SD +W+ RL+H + E + L C
Sbjct: 521 FPCDFSWGVTESVLKPESVASSPQFSDPHLYVWNATGNRLLH-RVEGVR-LKTRPAQCTD 578
Query: 240 YHLWERDIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPL 419
+ ++ +EM + + YRF+L W ++PTG + ++ +YY ++ L GI +
Sbjct: 579 FVNIKKQLEMLARMKVTHYRFALDWASVLPTGNLSAVNRQALRYYRCVVSEGLKLGISAM 638
Query: 420 VTIF-----HWDLPQSLQDLGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEPVSIC 584
VT++ H LP+ L GW+NP + F+ YA + F D VK W++INEP +
Sbjct: 639 VTLYYPTHAHLGLPEPLLHADGWLNPSTAEAFQAYAGLCFQELGDLVKLWITINEPNRLS 698
Query: 585 DYVYNTGG 608
D +YN G
Sbjct: 699 D-IYNRSG 705
>Z92540-2|CAC94767.1| 273|Homo sapiens 179I15.1 (klotho) protein.
Length = 273
Score = 162 bits (394), Expect = 9e-40
Identities = 82/198 (41%), Positives = 110/198 (55%), Gaps = 16/198 (8%)
Frame = +3
Query: 78 TFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTN------------- 218
TFP GF + SA+YQ EG W KG SIWD H D N
Sbjct: 60 TFPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPLQP 119
Query: 219 --GDVTCDSYHLWERDIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDG 392
GDV DSY+ RD E ELG+ YRFS+SW R++P G + + +G +YY L++
Sbjct: 120 ATGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLER 179
Query: 393 LLDKGIEPLVTIFHWDLPQSLQD-LGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINE 569
L + G++P+VT++HWDLPQ LQD GGW N + D F DYA + F F +VK W++I+
Sbjct: 180 LRELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITIDN 239
Query: 570 PVSICDYVYNTGGMAPPI 623
P + + Y TG +AP I
Sbjct: 240 PYVVAWHGYATGRLAPGI 257
>AL161898-1|CAH71888.1| 1012|Homo sapiens klotho protein.
Length = 1012
Score = 162 bits (394), Expect = 9e-40
Identities = 82/198 (41%), Positives = 110/198 (55%), Gaps = 16/198 (8%)
Frame = +3
Query: 78 TFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTN------------- 218
TFP GF + SA+YQ EG W KG SIWD H D N
Sbjct: 60 TFPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPLQP 119
Query: 219 --GDVTCDSYHLWERDIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDG 392
GDV DSY+ RD E ELG+ YRFS+SW R++P G + + +G +YY L++
Sbjct: 120 ATGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLER 179
Query: 393 LLDKGIEPLVTIFHWDLPQSLQD-LGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINE 569
L + G++P+VT++HWDLPQ LQD GGW N + D F DYA + F F +VK W++I+
Sbjct: 180 LRELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITIDN 239
Query: 570 PVSICDYVYNTGGMAPPI 623
P + + Y TG +AP I
Sbjct: 240 PYVVAWHGYATGRLAPGI 257
Score = 72.1 bits (169), Expect = 2e-12
Identities = 50/177 (28%), Positives = 81/177 (45%), Gaps = 12/177 (6%)
Frame = +3
Query: 78 TFPPGFKFGAASASYQVEGAWN-VSDKGESIWDRLVHTKPEAIMDLTNGDVT------CD 236
TFP F +G QV+ + +D +WD VH I +G VT C
Sbjct: 518 TFPCDFAWGVVDNYIQVDTTLSQFTDLNVYLWD--VHHSKRLIK--VDGVVTKKRKSYCV 573
Query: 237 SYHLWERDIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEP 416
+ + I + E+ + +RFSL W ++P G ++++ +YY + L+ I P
Sbjct: 574 DFAAIQPQIALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNITP 633
Query: 417 LVTIF-----HWDLPQSLQDLGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEP 572
+V ++ + LP+ L G W NP F +YAR+ F VK W+++NEP
Sbjct: 634 VVALWQPMAPNQGLPRLLARQGAWENPYTALAFAEYARLCFQELGHHVKLWITMNEP 690
>AB009667-2|BAA24941.1| 549|Homo sapiens Klotho protein (KL)
protein.
Length = 549
Score = 162 bits (394), Expect = 9e-40
Identities = 82/198 (41%), Positives = 110/198 (55%), Gaps = 16/198 (8%)
Frame = +3
Query: 78 TFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTN------------- 218
TFP GF + SA+YQ EG W KG SIWD H D N
Sbjct: 60 TFPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPLQP 119
Query: 219 --GDVTCDSYHLWERDIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDG 392
GDV DSY+ RD E ELG+ YRFS+SW R++P G + + +G +YY L++
Sbjct: 120 ATGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLER 179
Query: 393 LLDKGIEPLVTIFHWDLPQSLQD-LGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINE 569
L + G++P+VT++HWDLPQ LQD GGW N + D F DYA + F F +VK W++I+
Sbjct: 180 LRELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITIDN 239
Query: 570 PVSICDYVYNTGGMAPPI 623
P + + Y TG +AP I
Sbjct: 240 PYVVAWHGYATGRLAPGI 257
>AB009667-1|BAA24940.1| 1012|Homo sapiens Klotho protein (KL)
protein.
Length = 1012
Score = 162 bits (394), Expect = 9e-40
Identities = 82/198 (41%), Positives = 110/198 (55%), Gaps = 16/198 (8%)
Frame = +3
Query: 78 TFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTN------------- 218
TFP GF + SA+YQ EG W KG SIWD H D N
Sbjct: 60 TFPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPLQP 119
Query: 219 --GDVTCDSYHLWERDIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDG 392
GDV DSY+ RD E ELG+ YRFS+SW R++P G + + +G +YY L++
Sbjct: 120 ATGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLER 179
Query: 393 LLDKGIEPLVTIFHWDLPQSLQD-LGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINE 569
L + G++P+VT++HWDLPQ LQD GGW N + D F DYA + F F +VK W++I+
Sbjct: 180 LRELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITIDN 239
Query: 570 PVSICDYVYNTGGMAPPI 623
P + + Y TG +AP I
Sbjct: 240 PYVVAWHGYATGRLAPGI 257
Score = 72.1 bits (169), Expect = 2e-12
Identities = 50/177 (28%), Positives = 81/177 (45%), Gaps = 12/177 (6%)
Frame = +3
Query: 78 TFPPGFKFGAASASYQVEGAWN-VSDKGESIWDRLVHTKPEAIMDLTNGDVT------CD 236
TFP F +G QV+ + +D +WD VH I +G VT C
Sbjct: 518 TFPCDFAWGVVDNYIQVDTTLSQFTDLNVYLWD--VHHSKRLIK--VDGVVTKKRKSYCV 573
Query: 237 SYHLWERDIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEP 416
+ + I + E+ + +RFSL W ++P G ++++ +YY + L+ I P
Sbjct: 574 DFAAIQPQIALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNITP 633
Query: 417 LVTIF-----HWDLPQSLQDLGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEP 572
+V ++ + LP+ L G W NP F +YAR+ F VK W+++NEP
Sbjct: 634 VVALWQPMAPNQGLPRLLARQGAWENPYTALAFAEYARLCFQELGHHVKLWITMNEP 690
>AB005142-1|BAA23382.1| 1012|Homo sapiens klotho protein.
Length = 1012
Score = 162 bits (394), Expect = 9e-40
Identities = 82/198 (41%), Positives = 110/198 (55%), Gaps = 16/198 (8%)
Frame = +3
Query: 78 TFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTN------------- 218
TFP GF + SA+YQ EG W KG SIWD H D N
Sbjct: 60 TFPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPLQP 119
Query: 219 --GDVTCDSYHLWERDIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDG 392
GDV DSY+ RD E ELG+ YRFS+SW R++P G + + +G +YY L++
Sbjct: 120 ATGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLER 179
Query: 393 LLDKGIEPLVTIFHWDLPQSLQD-LGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINE 569
L + G++P+VT++HWDLPQ LQD GGW N + D F DYA + F F +VK W++I+
Sbjct: 180 LRELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITIDN 239
Query: 570 PVSICDYVYNTGGMAPPI 623
P + + Y TG +AP I
Sbjct: 240 PYVVAWHGYATGRLAPGI 257
Score = 72.1 bits (169), Expect = 2e-12
Identities = 50/177 (28%), Positives = 81/177 (45%), Gaps = 12/177 (6%)
Frame = +3
Query: 78 TFPPGFKFGAASASYQVEGAWN-VSDKGESIWDRLVHTKPEAIMDLTNGDVT------CD 236
TFP F +G QV+ + +D +WD VH I +G VT C
Sbjct: 518 TFPCDFAWGVVDNYIQVDTTLSQFTDLNVYLWD--VHHSKRLIK--VDGVVTKKRKSYCV 573
Query: 237 SYHLWERDIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEP 416
+ + I + E+ + +RFSL W ++P G ++++ +YY + L+ I P
Sbjct: 574 DFAAIQPQIALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNITP 633
Query: 417 LVTIF-----HWDLPQSLQDLGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEP 572
+V ++ + LP+ L G W NP F +YAR+ F VK W+++NEP
Sbjct: 634 VVALWQPMAPNQGLPRLLARQGAWENPYTALAFAEYARLCFQELGHHVKLWITMNEP 690
>BC109377-1|AAI09378.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 103 bits (248), Expect = 4e-22
Identities = 44/94 (46%), Positives = 58/94 (61%)
Frame = +3
Query: 75 LTFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWE 254
+ FP GF + AA+A+YQVEG W+ KG +WD H E + GDV C SY LWE
Sbjct: 1 MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWE 60
Query: 255 RDIEMATELGLHFYRFSLSWPRLMPTGFSNKISE 356
D++ +LGL YRFSLSW RL+P G + I++
Sbjct: 61 EDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQ 94
>BC029362-1|AAH29362.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 103 bits (248), Expect = 4e-22
Identities = 44/94 (46%), Positives = 58/94 (61%)
Frame = +3
Query: 75 LTFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWE 254
+ FP GF + AA+A+YQVEG W+ KG +WD H E + GDV C SY LWE
Sbjct: 1 MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWE 60
Query: 255 RDIEMATELGLHFYRFSLSWPRLMPTGFSNKISE 356
D++ +LGL YRFSLSW RL+P G + I++
Sbjct: 61 EDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQ 94
>BC070188-1|AAH70188.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 103 bits (246), Expect = 7e-22
Identities = 44/94 (46%), Positives = 58/94 (61%)
Frame = +3
Query: 75 LTFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWE 254
+ FP GF + AA+A+YQVEG W+ KG +WD H E + GDV C SY LWE
Sbjct: 1 MAFPAGFGWAAATAAYQVEGGWDADGKGLCVWDTFTHQGGERVFKNQTGDVACGSYTLWE 60
Query: 255 RDIEMATELGLHFYRFSLSWPRLMPTGFSNKISE 356
D++ +LGL YRFSLSW RL+P G + I++
Sbjct: 61 EDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQ 94
>Z84483-1|CAC94773.1| 739|Homo sapiens 46H23.1 (Klotho) protein.
Length = 739
Score = 72.1 bits (169), Expect = 2e-12
Identities = 50/177 (28%), Positives = 81/177 (45%), Gaps = 12/177 (6%)
Frame = +3
Query: 78 TFPPGFKFGAASASYQVEGAWN-VSDKGESIWDRLVHTKPEAIMDLTNGDVT------CD 236
TFP F +G QV+ + +D +WD VH I +G VT C
Sbjct: 245 TFPCDFAWGVVDNYIQVDTTLSQFTDLNVYLWD--VHHSKRLIK--VDGVVTKKRKSYCV 300
Query: 237 SYHLWERDIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEP 416
+ + I + E+ + +RFSL W ++P G ++++ +YY + L+ I P
Sbjct: 301 DFAAIQPQIALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNITP 360
Query: 417 LVTIF-----HWDLPQSLQDLGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEP 572
+V ++ + LP+ L G W NP F +YAR+ F VK W+++NEP
Sbjct: 361 VVALWQPMAPNQGLPRLLARQGAWENPYTALAFAEYARLCFQELGHHVKLWITMNEP 417
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 103,197,727
Number of Sequences: 237096
Number of extensions: 2361764
Number of successful extensions: 12277
Number of sequences better than 10.0: 23
Number of HSP's better than 10.0 without gapping: 12072
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 12246
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 7253890590
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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