Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= bmmt6b02
(622 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q9UJ83 Cluster: 2-hydroxyacyl-CoA lyase 1; n=40; Eukary... 193 2e-48
UniRef50_Q17474 Cluster: Putative uncharacterized protein; n=3; ... 179 4e-44
UniRef50_A0CTV7 Cluster: Chromosome undetermined scaffold_27, wh... 149 4e-35
UniRef50_A4VE07 Cluster: 2-hydroxyphytanoyl-CoA lyase, putative;... 146 3e-34
UniRef50_Q9Y7M1 Cluster: Oxalyl-CoA decarboxylase; n=5; Fungi/Me... 142 5e-33
UniRef50_Q54DA9 Cluster: Putative uncharacterized protein; n=1; ... 135 7e-31
UniRef50_Q9FNY6 Cluster: Oxalyl-CoA decarboxylase; n=13; Magnoli... 135 9e-31
UniRef50_P39994 Cluster: Uncharacterized protein YEL020C; n=3; S... 124 1e-27
UniRef50_Q757R7 Cluster: AEL055Cp; n=1; Eremothecium gossypii|Re... 123 4e-27
UniRef50_A7TJH4 Cluster: Putative uncharacterized protein; n=1; ... 109 4e-23
UniRef50_P40149 Cluster: Oxalyl-CoA decarboxylase; n=60; Bacteri... 107 2e-22
UniRef50_UPI0000383380 Cluster: COG0028: Thiamine pyrophosphate-... 103 5e-21
UniRef50_Q75PZ0 Cluster: Oxalyl-CoA decarboxylase; n=1; Bifidoba... 98 1e-19
UniRef50_A7QY67 Cluster: Chromosome undetermined scaffold_240, w... 98 2e-19
UniRef50_UPI000150A350 Cluster: Thiamine pyrophosphate enzyme, c... 94 3e-18
UniRef50_A7H9A1 Cluster: Thiamine pyrophosphate protein central ... 89 6e-17
UniRef50_Q9HKB0 Cluster: Acetolactate synthase, large chain rela... 88 2e-16
UniRef50_A0LEZ5 Cluster: Thiamine pyrophosphate enzyme TPP bindi... 86 7e-16
UniRef50_P17597 Cluster: Acetolactate synthase, chloroplast prec... 85 1e-15
UniRef50_A2SP25 Cluster: Acetolactate synthase-like TPP-requirin... 84 2e-15
UniRef50_Q2NGQ0 Cluster: Predicted thiamine pyrophosphate-requir... 84 2e-15
UniRef50_Q607C4 Cluster: Acetolactate synthase; n=1; Methylococc... 83 4e-15
UniRef50_Q03UU2 Cluster: Acetolactate synthase; n=2; Leuconostoc... 82 9e-15
UniRef50_A7QYX6 Cluster: Chromosome chr16 scaffold_258, whole ge... 82 9e-15
UniRef50_Q6L042 Cluster: Acetolactate synthase; n=6; Archaea|Rep... 81 2e-14
UniRef50_Q7U5G1 Cluster: Acetolactate synthase large subunit; n=... 81 2e-14
UniRef50_UPI0001597788 Cluster: IlvB; n=1; Bacillus amyloliquefa... 80 4e-14
UniRef50_A4ABB6 Cluster: Pyruvate decarboxylase; n=2; Proteobact... 80 5e-14
UniRef50_Q6AJI2 Cluster: Acetolactate synthase; n=42; cellular o... 79 6e-14
UniRef50_A6G0J0 Cluster: Thiamine pyrophosphate enzyme-like TPP ... 79 8e-14
UniRef50_Q8U2A4 Cluster: Acetolactate synthase; n=4; cellular or... 79 8e-14
UniRef50_Q12ZE1 Cluster: Thiamine pyrophosphate requiring enzyme... 79 8e-14
UniRef50_Q8A609 Cluster: Acetolactate synthase; n=30; Bacteria|R... 79 1e-13
UniRef50_A4AC84 Cluster: Acetolactate synthase; n=2; cellular or... 79 1e-13
UniRef50_Q67QP4 Cluster: Acetolactate synthase-like TPP-requirin... 78 1e-13
UniRef50_A5ZR04 Cluster: Acetolactate synthase; n=3; Clostridial... 78 1e-13
UniRef50_A7DN45 Cluster: Acetolactate synthase, large subunit, b... 78 2e-13
UniRef50_Q3IXG3 Cluster: Thiamine pyrophosphate-requiring enzyme... 77 3e-13
UniRef50_Q9X5G0 Cluster: Acetolactate synthase; n=57; Bacteria|R... 77 3e-13
UniRef50_A3H9A0 Cluster: Thiamine pyrophosphate enzyme-like TPP-... 77 3e-13
UniRef50_O68497 Cluster: Catabolic acetolactate synthase; n=11; ... 77 5e-13
UniRef50_A1ICC6 Cluster: Putative TPP-requiring enzyme; n=1; Can... 77 5e-13
UniRef50_Q04789 Cluster: Acetolactate synthase; n=69; Bacteria|R... 77 5e-13
UniRef50_Q9WZ18 Cluster: Acetolactate synthase; n=7; cellular or... 76 6e-13
UniRef50_Q89N19 Cluster: Blr4023 protein; n=72; Bacteria|Rep: Bl... 76 6e-13
UniRef50_Q5LKS2 Cluster: Sulphoacetaldehyde acetyltransferase, p... 76 6e-13
UniRef50_Q3AM88 Cluster: Alpha-acetolactate synthase; RBL02971; ... 76 6e-13
UniRef50_Q1ARE6 Cluster: Acetolactate synthase; n=4; Bacteria|Re... 76 6e-13
UniRef50_Q18S72 Cluster: Thiamine pyrophosphate enzyme-like TPP ... 76 6e-13
UniRef50_Q5V522 Cluster: Acetolactate synthase; n=4; cellular or... 76 6e-13
UniRef50_P73918 Cluster: Acetolactate synthase; n=6; Bacteria|Re... 76 8e-13
UniRef50_A3DID9 Cluster: Acetolactate synthase; n=3; Clostridium... 75 1e-12
UniRef50_Q8TR30 Cluster: Acetolactate synthase, large subunit; n... 75 1e-12
UniRef50_A7D3B0 Cluster: Acetolactate synthase, large subunit, b... 75 1e-12
UniRef50_Q1LF51 Cluster: Thiamine pyrophosphate enzyme-like TPP ... 74 2e-12
UniRef50_A1HPN8 Cluster: Acetolactate synthase, large subunit, b... 74 3e-12
UniRef50_P40811 Cluster: Acetolactate synthase isozyme 3 large s... 74 3e-12
UniRef50_A4F7C5 Cluster: Acetolactate synthase large subunit; n=... 73 4e-12
UniRef50_Q0PAU3 Cluster: Acetolactate synthase large subunit; n=... 73 6e-12
UniRef50_A5GC69 Cluster: Acetolactate synthase; n=3; cellular or... 73 6e-12
UniRef50_Q7W2M5 Cluster: Acetolactate synthase large subunit; n=... 73 7e-12
UniRef50_Q39P46 Cluster: Acetolactate synthase, large subunit; n... 73 7e-12
UniRef50_O27639 Cluster: Acetolactate synthase, large subunit ho... 73 7e-12
UniRef50_Q6DDK5 Cluster: Ilvbl-prov protein; n=2; Bilateria|Rep:... 72 1e-11
UniRef50_Q8G7H0 Cluster: Acetolactate synthase; n=2; Bifidobacte... 72 1e-11
UniRef50_P96591 Cluster: YdaP protein; n=11; Bacillaceae|Rep: Yd... 72 1e-11
UniRef50_Q28MM5 Cluster: Thiamine pyrophosphate enzyme-like TPP ... 72 1e-11
UniRef50_Q97EE4 Cluster: Acetolactate synthase; n=10; Clostridia... 71 2e-11
UniRef50_Q0SHU3 Cluster: Pyruvate dehydrogenase; n=15; Bacteria|... 71 2e-11
UniRef50_O28494 Cluster: Acetolactate synthase, large subunit; n... 71 2e-11
UniRef50_Q82PG6 Cluster: Putative pyruvate dehydrogenase/oxidase... 71 3e-11
UniRef50_A7R4D4 Cluster: Chromosome undetermined scaffold_656, w... 71 3e-11
UniRef50_P66947 Cluster: Probable acetolactate synthase; n=12; M... 71 3e-11
UniRef50_Q89R07 Cluster: Bll2965 protein; n=4; Bacteria|Rep: Bll... 70 4e-11
UniRef50_Q04D18 Cluster: Thiamine pyrophosphate-requiring enzyme... 70 4e-11
UniRef50_A6DLM5 Cluster: Acetolactate synthase; n=1; Lentisphaer... 70 4e-11
UniRef50_A1WES2 Cluster: Thiamine pyrophosphate enzyme TPP bindi... 70 4e-11
UniRef50_Q01Q83 Cluster: Thiamine pyrophosphate enzyme domain pr... 70 5e-11
UniRef50_A0PNI1 Cluster: Acetolactate synthase (Large subunit) I... 70 5e-11
UniRef50_Q8TPF5 Cluster: Acetolactate synthase; n=12; cellular o... 70 5e-11
UniRef50_P00892 Cluster: Acetolactate synthase isozyme 2 large s... 70 5e-11
UniRef50_Q04524 Cluster: Acetolactate synthase, catabolic; n=25;... 70 5e-11
UniRef50_Q186C0 Cluster: Acetolactate synthase; n=2; Clostridium... 69 7e-11
UniRef50_Q54YW0 Cluster: Putative uncharacterized protein; n=3; ... 69 7e-11
UniRef50_Q93PS3 Cluster: Sulfoacetaldehyde acetyltransferase; n=... 69 9e-11
UniRef50_P07342 Cluster: Acetolactate synthase catalytic subunit... 69 9e-11
UniRef50_P08142 Cluster: Acetolactate synthase isozyme 1 large s... 69 9e-11
UniRef50_Q4KD62 Cluster: Acetolactate synthase, large subunit, p... 69 1e-10
UniRef50_Q8F341 Cluster: Acetolactate synthase large subunit; n=... 68 2e-10
UniRef50_Q5LLG2 Cluster: Thiamine pyrophosphate-dependent enzyme... 68 2e-10
UniRef50_Q96F08 Cluster: IlvB (Bacterial acetolactate synthase)-... 68 2e-10
UniRef50_Q59GP4 Cluster: IlvB (Bacterial acetolactate synthase)-... 68 2e-10
UniRef50_Q64QU8 Cluster: Pyruvate dehydrogenase; n=6; Bacteroide... 68 2e-10
UniRef50_Q0S4P5 Cluster: Acetolactate synthase large subunit; n=... 68 2e-10
UniRef50_A0VUP0 Cluster: Thiamine pyrophosphate enzyme TPP bindi... 68 2e-10
UniRef50_Q0CI52 Cluster: Putative uncharacterized protein; n=1; ... 68 2e-10
UniRef50_Q2SEE0 Cluster: Thiamine pyrophosphate-requiring enzyme... 67 3e-10
UniRef50_Q1IPP8 Cluster: Thiamine pyrophosphate enzyme-like TPP-... 67 3e-10
UniRef50_Q05FL3 Cluster: Acetolactate synthase large subunit; n=... 67 3e-10
UniRef50_A2QFR5 Cluster: Acetolactate synthase; n=3; Aspergillus... 67 3e-10
UniRef50_Q63PK8 Cluster: Acetolactate synthase isozyme II large ... 67 4e-10
UniRef50_Q2SJ09 Cluster: Thiamine pyrophosphate-requiring enzyme... 67 4e-10
UniRef50_Q84H41 Cluster: Sulfoacetaldehyde acetyltransferase; n=... 67 4e-10
UniRef50_Q8ELJ0 Cluster: Acetolactate synthase large subunit; n=... 66 5e-10
UniRef50_A1SHD8 Cluster: Thiamine pyrophosphate enzyme domain pr... 66 5e-10
UniRef50_Q8A6Q6 Cluster: Pyruvate dehydrogenase; n=6; Bacteria|R... 66 6e-10
UniRef50_A7CXZ6 Cluster: Thiamine pyrophosphate protein TPP bind... 66 6e-10
UniRef50_Q0FGP6 Cluster: Acetolactate synthase II large subunit;... 66 8e-10
UniRef50_A5TSK5 Cluster: Acetolactate synthase; n=1; Fusobacteri... 66 8e-10
UniRef50_A3X9K6 Cluster: Acetolactate synthase-like TPP-requirin... 66 8e-10
UniRef50_Q02137 Cluster: Acetolactate synthase large subunit; n=... 66 8e-10
UniRef50_Q28W58 Cluster: Thiamine pyrophosphate enzyme-like TPP-... 65 1e-09
UniRef50_Q1N3D1 Cluster: Pyruvate oxidase; n=2; Gammaproteobacte... 65 1e-09
UniRef50_A6BEJ7 Cluster: Acetolactate synthase; n=3; Clostridial... 65 1e-09
UniRef50_A4R4K6 Cluster: Putative uncharacterized protein; n=2; ... 65 1e-09
UniRef50_O05031 Cluster: Uncharacterized protein HI0737; n=11; H... 65 1e-09
UniRef50_Q6N658 Cluster: Possible benzaldehyde lyase; n=2; Rhodo... 65 1e-09
UniRef50_Q2S0N1 Cluster: Acetolactate synthase, large subunit, b... 65 1e-09
UniRef50_A6UGS0 Cluster: Thiamine pyrophosphate protein domain p... 65 1e-09
UniRef50_UPI0000F347A9 Cluster: UPI0000F347A9 related cluster; n... 64 2e-09
UniRef50_Q8EN64 Cluster: Acetolactate synthase; n=24; cellular o... 64 2e-09
UniRef50_Q7WA22 Cluster: Acetolactate synthase large subunit; n=... 64 2e-09
UniRef50_A1VPE3 Cluster: Transcriptional regulator, Fis family; ... 64 2e-09
UniRef50_O26576 Cluster: Pyruvate dehydrogenase / acetolactate s... 64 2e-09
UniRef50_UPI00015BB008 Cluster: acetolactate synthase, large sub... 64 3e-09
UniRef50_Q74H96 Cluster: Pyruvate oxidase; n=1; Lactobacillus jo... 64 3e-09
UniRef50_Q2AIK5 Cluster: Thiamine pyrophosphate enzyme, C-termin... 64 3e-09
UniRef50_Q8PT77 Cluster: Acetolactate synthase; n=4; cellular or... 64 3e-09
UniRef50_Q2NI87 Cluster: Acetolactate synthase; n=2; Methanospha... 64 3e-09
UniRef50_Q6D0F1 Cluster: Acetolactate synthase isozyme I large s... 64 3e-09
UniRef50_Q41EN3 Cluster: Pyruvate decarboxylase; n=1; Exiguobact... 64 3e-09
UniRef50_Q168P2 Cluster: Acetohydroxy acid synthase large subuni... 64 3e-09
UniRef50_Q5IWY3 Cluster: Plastid acetolactate synthase large sub... 64 3e-09
UniRef50_O08353 Cluster: Probable acetolactate synthase large su... 64 3e-09
UniRef50_Q3SL06 Cluster: Acetolactate synthase large subunit; n=... 63 4e-09
UniRef50_A5V6Y6 Cluster: Thiamine pyrophosphate enzyme domain pr... 63 4e-09
UniRef50_Q5LQV0 Cluster: Benzaldehyde lyase, putative; n=1; Sili... 63 6e-09
UniRef50_A3JPU7 Cluster: Acetolactate synthase, large subunit, p... 63 6e-09
UniRef50_P07003 Cluster: Pyruvate dehydrogenase [cytochrome] (EC... 63 6e-09
UniRef50_A4AL48 Cluster: Putative uncharacterized protein; n=1; ... 62 8e-09
UniRef50_UPI000050F94C Cluster: COG0028: Thiamine pyrophosphate-... 62 1e-08
UniRef50_Q1ILZ1 Cluster: Acetolactate synthase; n=5; cellular or... 62 1e-08
UniRef50_Q13I72 Cluster: Putative pyruvate decarboxylase; n=1; B... 62 1e-08
UniRef50_Q6PST7 Cluster: CidC; n=30; Bacillales|Rep: CidC - Stap... 62 1e-08
UniRef50_Q3XZD0 Cluster: Pyruvate decarboxylase; n=3; Lactobacil... 62 1e-08
UniRef50_Q13G09 Cluster: Putative pyruvate decarboxylase; n=2; B... 62 1e-08
UniRef50_A4SWA9 Cluster: Thiamine pyrophosphate enzyme domain pr... 62 1e-08
UniRef50_Q97UP3 Cluster: Acetolactate synthase large subunit hom... 62 1e-08
UniRef50_Q9RU76 Cluster: Acetolactate synthase; n=3; Bacteria|Re... 61 2e-08
UniRef50_Q88YC4 Cluster: Pyruvate oxidase; n=5; Lactobacillales|... 61 2e-08
UniRef50_Q2LXP1 Cluster: Acetolactate synthase large subunit; n=... 61 2e-08
UniRef50_Q1ATS7 Cluster: Thiamine pyrophosphate enzyme-like TPP ... 61 2e-08
UniRef50_A3PYZ1 Cluster: Thiamine pyrophosphate enzyme TPP bindi... 61 2e-08
UniRef50_A2U4W9 Cluster: Thiamine pyrophosphate enzyme-like TPP-... 61 2e-08
UniRef50_P42463 Cluster: Acetolactate synthase large subunit; n=... 61 2e-08
UniRef50_Q6F7C0 Cluster: Pyruvate dehydrogenase; n=7; Proteobact... 61 2e-08
UniRef50_A5W0I1 Cluster: Thiamine pyrophosphate enzyme TPP bindi... 61 2e-08
UniRef50_Q7RCT1 Cluster: Peroxisomal-coenzyme a synthetase; n=5;... 60 3e-08
UniRef50_A1ULA9 Cluster: Thiamine pyrophosphate enzyme TPP bindi... 60 4e-08
UniRef50_A0K0V5 Cluster: Thiamine pyrophosphate enzyme domain pr... 60 4e-08
UniRef50_A0IIS8 Cluster: Thiamine pyrophosphate enzyme-like TPP-... 60 4e-08
UniRef50_Q7NTF5 Cluster: Benzoylformate decarboxylase; n=2; cell... 60 6e-08
UniRef50_O28264 Cluster: Acetolactate synthase, large subunit; n... 60 6e-08
UniRef50_Q3JBM9 Cluster: Acetolactate synthase large subunit; n=... 59 7e-08
UniRef50_A6G7M7 Cluster: Acetolactate synthase large subunit; n=... 59 7e-08
UniRef50_A3JLQ7 Cluster: Sulphoacetaldehyde acetyltransferase, p... 59 7e-08
UniRef50_Q2U8M9 Cluster: Thiamine pyrophosphate-requiring enzyme... 59 7e-08
UniRef50_Q0CL07 Cluster: Predicted protein; n=1; Aspergillus ter... 59 7e-08
UniRef50_Q5FHQ7 Cluster: Pyruvate oxidase; n=12; Lactobacillacea... 59 1e-07
UniRef50_A6NPM8 Cluster: Acetolactate synthase; n=2; Bacteria|Re... 59 1e-07
UniRef50_A6E1Z9 Cluster: Acetolactate synthase II large subunit;... 59 1e-07
UniRef50_A4A3X6 Cluster: Acetolactate synthase isozyme I large s... 59 1e-07
UniRef50_A5UL13 Cluster: Acetolactate synthase (TPP-requiring), ... 59 1e-07
UniRef50_Q89F88 Cluster: Acetolactate synthase large subunit; n=... 58 1e-07
UniRef50_Q1GFA1 Cluster: Thiamine pyrophosphate enzyme-like TPP-... 58 1e-07
UniRef50_Q6JHM8 Cluster: Acetolactate synthase; n=1; Saccharopol... 58 2e-07
UniRef50_A5WFU5 Cluster: Pyruvate oxidase; n=1; Psychrobacter sp... 58 2e-07
UniRef50_A3VG64 Cluster: Acetolactate synthase large subunit; n=... 58 2e-07
UniRef50_A5K231 Cluster: Bi-functional enzyme: long-chain fatty-... 58 2e-07
UniRef50_Q5WGG1 Cluster: Acetolactate synthase large subunit; n=... 58 2e-07
UniRef50_Q5LPG3 Cluster: Acetolactate synthase, catabolic, putat... 58 2e-07
UniRef50_A0JT80 Cluster: Thiamine pyrophosphate enzyme TPP bindi... 58 2e-07
UniRef50_Q988P8 Cluster: Acetolactate synthase, large subunit; n... 57 3e-07
UniRef50_Q88S56 Cluster: Pyruvate oxidase; n=2; Lactobacillus pl... 57 3e-07
UniRef50_P37063 Cluster: Pyruvate oxidase; n=2; Lactobacillus pl... 57 3e-07
UniRef50_Q8KTR7 Cluster: Valine sensitive acetolactate synthase ... 57 4e-07
UniRef50_A4IL27 Cluster: Acetolactate synthase; n=1; Geobacillus... 57 4e-07
UniRef50_A3T0A3 Cluster: Acetolactate synthase II large subunit;... 57 4e-07
UniRef50_A5US79 Cluster: Thiamine pyrophosphate enzyme, central ... 56 5e-07
UniRef50_A1G7C7 Cluster: Thiamine pyrophosphate enzyme-like TPP-... 56 7e-07
UniRef50_O28180 Cluster: Acetolactate synthase, large subunit; n... 56 7e-07
UniRef50_UPI000050F80A Cluster: COG0028: Thiamine pyrophosphate-... 56 9e-07
UniRef50_Q6LF61 Cluster: Putative bi-functional enzyme: long-cha... 56 9e-07
UniRef50_UPI000050FC62 Cluster: COG0028: Thiamine pyrophosphate-... 55 1e-06
UniRef50_A1BBV8 Cluster: Thiamine pyrophosphate enzyme domain pr... 55 1e-06
UniRef50_Q2GMZ7 Cluster: Putative uncharacterized protein; n=1; ... 55 1e-06
UniRef50_Q3JVP4 Cluster: Pyruvate oxidase; n=17; Bacteria|Rep: P... 55 2e-06
UniRef50_Q2JA30 Cluster: Thiamine pyrophosphate enzyme-like TPP ... 55 2e-06
UniRef50_Q11NN4 Cluster: Acetolactate synthase, large subunit; n... 55 2e-06
UniRef50_A5MZ19 Cluster: Acetolactate synthase; n=1; Clostridium... 55 2e-06
UniRef50_A3U199 Cluster: Acetolactate synthase II large subunit;... 55 2e-06
UniRef50_Q5UWG1 Cluster: Acetolactate synthase large subunit; n=... 55 2e-06
UniRef50_A6LX01 Cluster: Thiamine pyrophosphate protein, central... 54 2e-06
UniRef50_A0WA20 Cluster: Thiamine pyrophosphate enzyme-like TPP ... 54 2e-06
UniRef50_Q88Y01 Cluster: Acetolactate synthase; n=25; Bacilli|Re... 54 3e-06
UniRef50_Q3A842 Cluster: Acetolactate synthase large subunit; n=... 54 3e-06
UniRef50_Q11CB6 Cluster: Thiamine pyrophosphate enzyme-like TPP-... 54 3e-06
UniRef50_Q036H9 Cluster: Pyruvate oxidase; n=1; Lactobacillus ca... 54 3e-06
UniRef50_A6BCA9 Cluster: Acetolactate synthase II large subunit;... 54 4e-06
UniRef50_A1SLX3 Cluster: Thiamine pyrophosphate enzyme domain pr... 54 4e-06
UniRef50_A1ULG6 Cluster: Thiamine pyrophosphate enzyme domain pr... 53 5e-06
UniRef50_Q8EC82 Cluster: Acetolactate synthase isozyme I, large ... 53 6e-06
UniRef50_Q88U88 Cluster: Pyruvate oxidase; n=5; Lactobacillaceae... 53 6e-06
UniRef50_A7DF15 Cluster: Thiamine pyrophosphate enzyme TPP bindi... 53 6e-06
UniRef50_Q92UW6 Cluster: Probable sulfoacetaldehyde acetyltransf... 53 6e-06
UniRef50_Q8ZTD9 Cluster: Acetolactate synthase; n=5; Thermoprote... 52 8e-06
UniRef50_A0YVD9 Cluster: Indole-3-pyruvate decarboxylase; n=1; L... 52 1e-05
UniRef50_Q1GGF3 Cluster: Thiamine pyrophosphate enzyme-like TPP-... 52 1e-05
UniRef50_A6G882 Cluster: Acetolactate synthase large subunit; n=... 52 1e-05
UniRef50_Q13H77 Cluster: Putative pyruvate decarboxylase; n=1; B... 51 2e-05
UniRef50_A6X6D0 Cluster: Thiamine pyrophosphate protein central ... 51 2e-05
UniRef50_A1G7W2 Cluster: Thiamine pyrophosphate enzyme-like TPP ... 51 2e-05
UniRef50_Q6D799 Cluster: Putative thiamine pyrophosphate enzyme;... 51 3e-05
UniRef50_Q54FW8 Cluster: Putative uncharacterized protein; n=1; ... 51 3e-05
UniRef50_A1R2T4 Cluster: Putative acetolactate synthase, large s... 50 3e-05
UniRef50_A0W3U9 Cluster: Thiamine pyrophosphate enzyme-like TPP ... 50 3e-05
UniRef50_A2Q9V6 Cluster: Catalytic activity: 2-acetolactate + CO... 50 3e-05
UniRef50_Q54970 Cluster: Pyruvate oxidase; n=21; Lactobacillales... 50 3e-05
UniRef50_A1WXE6 Cluster: Acetolactate synthase; n=6; Proteobacte... 50 4e-05
UniRef50_Q7WPE1 Cluster: Thiamine pyrophosphate enzyme; n=2; Pro... 50 6e-05
UniRef50_Q0K1D6 Cluster: Indole-3-pyruvate decarboxylase; n=2; B... 50 6e-05
UniRef50_A0QXQ7 Cluster: Putative acetolactate synthase; n=1; My... 50 6e-05
UniRef50_Q1YQE9 Cluster: Acetolactate synthase, large subunit; n... 49 8e-05
UniRef50_Q0JYE0 Cluster: Acetolactate synthase large subunit; n=... 49 8e-05
UniRef50_A4XBS4 Cluster: Thiamine pyrophosphate enzyme domain pr... 49 8e-05
UniRef50_A3U0U7 Cluster: Acetolactate synthase, large subunit; n... 49 8e-05
UniRef50_Q2FN41 Cluster: Thiamine pyrophosphate enzyme-like TPP-... 49 8e-05
UniRef50_Q9LCV9 Cluster: Carboxyethylarginine synthase; n=3; Str... 48 1e-04
UniRef50_A3JR28 Cluster: Putative uncharacterized protein; n=1; ... 48 1e-04
UniRef50_Q0U8P2 Cluster: Putative uncharacterized protein; n=1; ... 48 1e-04
UniRef50_Q6N2Y1 Cluster: Possible acetolactate synthase large su... 48 2e-04
UniRef50_A7D6S4 Cluster: Thiamine pyrophosphate enzyme domain pr... 48 2e-04
UniRef50_A0VEM6 Cluster: Thiamine pyrophosphate enzyme-like TPP-... 47 3e-04
UniRef50_Q2W979 Cluster: Thiamine pyrophosphate-requiring enzyme... 47 4e-04
UniRef50_Q7P747 Cluster: Acetolactate synthase; n=1; Fusobacteri... 47 4e-04
UniRef50_Q7NR95 Cluster: Acetolactate synthase; n=1; Chromobacte... 46 6e-04
UniRef50_Q2SM62 Cluster: Thiamine pyrophosphate-requiring enzyme... 46 6e-04
UniRef50_Q9K659 Cluster: Acetolactate synthase large subunit; n=... 46 7e-04
UniRef50_Q3A0L4 Cluster: Pyruvate decarboxylase; n=3; Bacteria|R... 46 7e-04
UniRef50_Q9Y8X5 Cluster: Putative acetolactate synthase; n=1; Ae... 46 7e-04
UniRef50_Q81QE0 Cluster: Indolepyruvate decarboxylase, putative;... 46 0.001
UniRef50_Q7WHS2 Cluster: Acetolactate synthase large subunit; n=... 46 0.001
UniRef50_Q8EP38 Cluster: Acetolactate synthase large subunit; n=... 45 0.001
UniRef50_A3K347 Cluster: Acetolactate synthase II large subunit;... 45 0.001
UniRef50_A4RJ96 Cluster: Putative uncharacterized protein; n=1; ... 45 0.001
UniRef50_P0AEP8 Cluster: Glyoxylate carboligase; n=131; Bacteria... 45 0.001
UniRef50_Q70I04 Cluster: Putative acetolactate synthase; n=1; St... 45 0.002
UniRef50_A6QC71 Cluster: Acetolactate synthase, large subunit; n... 45 0.002
UniRef50_Q2NGW8 Cluster: Predicted thiamine pyrophosphate enzyme... 45 0.002
UniRef50_Q58077 Cluster: Uncharacterized protein MJ0663; n=6; Me... 45 0.002
UniRef50_Q89D42 Cluster: MdlC protein; n=3; Bradyrhizobium|Rep: ... 44 0.002
UniRef50_Q60A74 Cluster: Decarboxylase, thiamine pyrophosphate e... 44 0.002
UniRef50_Q0PHX7 Cluster: IlvB; n=2; Bacteria|Rep: IlvB - Spiroch... 44 0.002
UniRef50_A6W4D4 Cluster: Thiamine pyrophosphate protein TPP bind... 44 0.002
UniRef50_Q6CA04 Cluster: Similar to sp|P26263 Saccharomyces cere... 44 0.002
UniRef50_A7BMR9 Cluster: Acetolactate synthase, large subunit, b... 44 0.003
UniRef50_A3W9K0 Cluster: Acetolactate synthase large subunit; n=... 44 0.003
UniRef50_Q979E0 Cluster: Benzoylformate decarboxylase; n=3; Ther... 44 0.003
UniRef50_A6PTN2 Cluster: Thiamine pyrophosphate enzyme TPP bindi... 44 0.004
UniRef50_Q5V5J6 Cluster: Acetolactate synthase large subunit; n=... 44 0.004
UniRef50_A5CNS1 Cluster: Putative acetolactate synthase; n=1; Cl... 43 0.005
UniRef50_Q126F4 Cluster: Thiamine pyrophosphate enzyme-like TPP ... 43 0.007
UniRef50_A1SCQ1 Cluster: Thiamine pyrophosphate enzyme domain pr... 43 0.007
UniRef50_UPI000038CADF Cluster: COG3961: Pyruvate decarboxylase ... 42 0.009
UniRef50_Q4FN91 Cluster: Acetolactate synthase II large chain; n... 42 0.009
UniRef50_Q1LM52 Cluster: Thiamine pyrophosphate enzyme-like TPP-... 42 0.009
UniRef50_Q0S7Z6 Cluster: Acetolactate synthase large subunit; n=... 42 0.009
UniRef50_A2BIK0 Cluster: IlvB (Bacterial acetolactate synthase)-... 42 0.012
UniRef50_Q5YN72 Cluster: Putative acetolactate synthase large su... 42 0.012
UniRef50_Q7D5H1 Cluster: Acetolactate synthase, large subunit, p... 42 0.012
UniRef50_Q4J9P1 Cluster: Thiamine pyrophosphate enzyme; n=2; Sul... 42 0.012
UniRef50_Q6QBS4 Cluster: Branched-chain alpha-ketoacid decarboxy... 42 0.016
UniRef50_Q2I6K8 Cluster: IlvB acetolactate synthase; n=1; uncult... 42 0.016
UniRef50_A0JTJ6 Cluster: Thiamine pyrophosphate enzyme TPP bindi... 42 0.016
UniRef50_Q2TX70 Cluster: Thiamine pyrophosphate-requiring enzyme... 42 0.016
UniRef50_Q1E1Z9 Cluster: Putative uncharacterized protein; n=1; ... 42 0.016
UniRef50_Q5LKG3 Cluster: Acetolactate synthase, large subunit, p... 41 0.021
UniRef50_Q025T6 Cluster: Thiamine pyrophosphate enzyme TPP bindi... 41 0.021
UniRef50_Q3A5I7 Cluster: Acetolactate synthase, large subunit; n... 41 0.027
UniRef50_Q0S9K9 Cluster: Probable acetolactate synthase large su... 41 0.027
UniRef50_A0IQZ1 Cluster: Thiamine pyrophosphate enzyme-like TPP ... 41 0.027
UniRef50_A3H9B0 Cluster: Acetolactate synthase-like TPP-requirin... 41 0.027
UniRef50_Q2BQJ0 Cluster: Pyruvate oxidase; n=2; Proteobacteria|R... 40 0.036
UniRef50_A5ICE7 Cluster: Myo-inositol catabolism protein IolD; n... 40 0.036
UniRef50_A6CP74 Cluster: Acetolactate synthase large subunit; n=... 40 0.048
UniRef50_Q6CPS1 Cluster: Similar to sgd|S0002788 Saccharomyces c... 40 0.048
UniRef50_Q12PG4 Cluster: Thiamine pyrophosphate enzyme-like TPP ... 40 0.063
UniRef50_Q11E64 Cluster: Thiamine pyrophosphate enzyme-like TPP-... 40 0.063
UniRef50_Q3M5M2 Cluster: Thiamine pyrophosphate enzyme; n=1; Ana... 39 0.084
UniRef50_A3JI96 Cluster: Acetolactate synthase II large subunit;... 39 0.084
UniRef50_A3H619 Cluster: Thiamine pyrophosphate enzyme-like TPP-... 39 0.084
UniRef50_P51844 Cluster: Pyruvate decarboxylase; n=9; Trichocoma... 39 0.084
UniRef50_Q7WPZ4 Cluster: Thiamine pyrophosphate enzyme; n=2; Bor... 39 0.11
UniRef50_Q7WCV8 Cluster: Putative acetolactate synthase large su... 39 0.11
UniRef50_Q5HKV0 Cluster: Indole-3-pyruvate decarboxylase; n=16; ... 39 0.11
UniRef50_Q8TW02 Cluster: Acetolactate synthase large subunit hom... 39 0.11
UniRef50_Q3IS45 Cluster: Thiamine pyrophosphate-requiring enzyme... 39 0.11
UniRef50_Q9WWE0 Cluster: AtrC; n=3; Rhizobiaceae|Rep: AtrC - Agr... 38 0.19
UniRef50_A0JZP6 Cluster: 2-succinyl-6-hydroxy-2, 4-cyclohexadien... 38 0.19
UniRef50_Q9UWY2 Cluster: Putative uncharacterized protein ORF-c2... 38 0.19
UniRef50_Q6N2J6 Cluster: Possible acetolactate synthase large su... 38 0.26
UniRef50_Q6W1J3 Cluster: IolD protein; n=1; Rhizobium sp. NGR234... 38 0.26
UniRef50_Q0PQN3 Cluster: Pyruvate:flavodoxin/ferredoxin oxidored... 38 0.26
UniRef50_A1WQL0 Cluster: Thiamine pyrophosphate enzyme TPP bindi... 38 0.26
UniRef50_A0KE44 Cluster: Thiamine pyrophosphate enzyme domain pr... 38 0.26
UniRef50_Q11E79 Cluster: Thiamine pyrophosphate enzyme-like TPP-... 37 0.34
UniRef50_A5ZRI3 Cluster: Putative uncharacterized protein; n=1; ... 37 0.34
UniRef50_A1K8D6 Cluster: Acetolactate synthase; n=2; Proteobacte... 37 0.34
UniRef50_Q06408 Cluster: Transaminated amino acid decarboxylase;... 37 0.34
UniRef50_Q1AVS4 Cluster: Thiamine pyrophosphate enzyme-like TPP ... 37 0.45
UniRef50_Q3ALE4 Cluster: Thiamine pyrophosphate-requiring enzyme... 36 0.59
UniRef50_A6CD43 Cluster: Pyruvate decarboxylase; n=1; Planctomyc... 36 0.59
UniRef50_Q2U0W7 Cluster: Thiamine pyrophosphate-requiring enzyme... 36 0.59
UniRef50_A3IED8 Cluster: 2-oxoglutarate decarboxylase; n=1; Baci... 36 0.78
UniRef50_P33287 Cluster: Pyruvate decarboxylase; n=3; Ascomycota... 36 0.78
UniRef50_P20906 Cluster: Benzoylformate decarboxylase; n=14; Bac... 36 0.78
UniRef50_P51853 Cluster: Benzaldehyde lyase; n=3; Pseudomonas fl... 36 0.78
UniRef50_Q11K52 Cluster: Thiamine pyrophosphate enzyme-like TPP-... 36 1.0
UniRef50_Q0LUC4 Cluster: Thiamine pyrophosphate enzyme, C-termin... 36 1.0
UniRef50_Q5CYA3 Cluster: Pyruvate decarboxylase; n=2; Cryptospor... 36 1.0
UniRef50_Q97V62 Cluster: Acetolactate synthase large subunit hom... 36 1.0
UniRef50_Q89QL7 Cluster: Bll3107 protein; n=2; Proteobacteria|Re... 35 1.8
UniRef50_A5IAA3 Cluster: Benzoylformate decarboxylase; n=5; Legi... 35 1.8
UniRef50_Q75BR0 Cluster: ACR211Wp; n=1; Eremothecium gossypii|Re... 35 1.8
UniRef50_Q0TZB1 Cluster: Putative uncharacterized protein; n=1; ... 35 1.8
UniRef50_Q1IMQ6 Cluster: Thiamine pyrophosphate enzyme-like TPP ... 34 2.4
UniRef50_Q97AL2 Cluster: Benzoylformate decarboxylase; n=2; Ther... 34 2.4
UniRef50_A7TRE3 Cluster: Putative uncharacterized protein; n=1; ... 34 3.1
UniRef50_P26263 Cluster: Pyruvate decarboxylase isozyme 3; n=26;... 34 3.1
UniRef50_Q4JT09 Cluster: 2-oxoglutarate decarboxylase / 2-succin... 33 4.2
UniRef50_A6EQY6 Cluster: 2-succinyl-6-hydroxy-2, 4-cyclohexadien... 33 4.2
UniRef50_Q6BSB5 Cluster: Similar to CA3367|IPF4667 Candida albic... 33 4.2
UniRef50_A7TK69 Cluster: Putative uncharacterized protein; n=1; ... 33 4.2
UniRef50_Q07S79 Cluster: Thiamine pyrophosphate enzyme TPP bindi... 33 5.5
UniRef50_A4AIZ7 Cluster: 2-oxoglutarate decarboxylase; n=1; mari... 33 5.5
UniRef50_A0LJD4 Cluster: Thiamine pyrophosphate enzyme domain pr... 33 5.5
UniRef50_Q15KI9 Cluster: Chloroplast Phyllo; n=9; cellular organ... 33 5.5
UniRef50_Q7VBN8 Cluster: 2-succinyl-6-hydroxy-2, 4-cyclohexadien... 33 7.3
UniRef50_Q2LTI3 Cluster: Acetolactate synthase; n=1; Syntrophus ... 33 7.3
UniRef50_A5GT34 Cluster: Menaquinone biosynthesis protein MenD; ... 33 7.3
UniRef50_A4AD90 Cluster: MFS transmembrane transporter protein; ... 33 7.3
UniRef50_A2Y970 Cluster: Putative uncharacterized protein; n=3; ... 33 7.3
UniRef50_A4YFS0 Cluster: Thiamine pyrophosphate enzyme TPP bindi... 33 7.3
UniRef50_UPI000051034A Cluster: COG0028: Thiamine pyrophosphate-... 32 9.6
UniRef50_A6AL55 Cluster: Putative EF hand domain/PKD domain prot... 32 9.6
UniRef50_A0G7U6 Cluster: RNA-directed DNA polymerase; n=4; Bacte... 32 9.6
>UniRef50_Q9UJ83 Cluster: 2-hydroxyacyl-CoA lyase 1; n=40;
Eukaryota|Rep: 2-hydroxyacyl-CoA lyase 1 - Homo sapiens
(Human)
Length = 578
Score = 193 bits (471), Expect = 2e-48
Identities = 84/130 (64%), Positives = 105/130 (80%)
Frame = +2
Query: 221 IDGNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYL 400
+ G ++A++LK Q VEY+FGIVGIPV E A+A Q G+KYIGMRNEQAACYAA A GYL
Sbjct: 14 VSGAKVIAQALKTQDVEYIFGIVGIPVTEIAIAAQQLGIKYIGMRNEQAACYAASAIGYL 73
Query: 401 TGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQVDSSRM 580
T +PGVCLVVSGPGL+H +GGMANA +NCWPL+VI GS + E +G FQE+PQV++ R+
Sbjct: 74 TSRPGVCLVVSGPGLIHALGGMANANMNCWPLLVIGGSSERNQETMGAFQEFPQVEACRL 133
Query: 581 YCKYAARPPS 610
Y K++ARP S
Sbjct: 134 YTKFSARPSS 143
>UniRef50_Q17474 Cluster: Putative uncharacterized protein; n=3;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 634
Score = 179 bits (436), Expect = 4e-44
Identities = 87/141 (61%), Positives = 102/141 (72%), Gaps = 2/141 (1%)
Frame = +2
Query: 194 SQKLNGSMG--IDGNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQA 367
S+KL G +DG +I A +LK QGVEY+FG+VG PVIE MA Q+ G+KYIG RNEQA
Sbjct: 61 SRKLRNHDGSNMDGASITAAALKSQGVEYMFGVVGFPVIEVGMAAQAHGIKYIGCRNEQA 120
Query: 368 ACYAAQATGYLTGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGF 547
A YAAQA GYLTGKP LVVSGPG+LH IGG+ANA VNCWP+V I G+ D E G F
Sbjct: 121 AAYAAQAMGYLTGKPVALLVVSGPGILHAIGGLANATVNCWPVVCIGGTADVDLENRGAF 180
Query: 548 QEWPQVDSSRMYCKYAARPPS 610
QEW Q +S R CK+ +RP S
Sbjct: 181 QEWSQQESVRNSCKHVSRPTS 201
>UniRef50_A0CTV7 Cluster: Chromosome undetermined scaffold_27, whole
genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_27,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 552
Score = 149 bits (362), Expect = 4e-35
Identities = 67/127 (52%), Positives = 88/127 (69%)
Frame = +2
Query: 221 IDGNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYL 400
I GN ++A+S + ++YVFGIVG+PVIE AFQ+ G++Y G RNEQ A YA A GYL
Sbjct: 2 ISGNQVIAQSFAQNHLKYVFGIVGVPVIELGYAFQAQGMEYYGFRNEQGASYACGAIGYL 61
Query: 401 TGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQVDSSRM 580
T P VCLVVSGPGL+H + G ANAQVN WP+V++AGS ++ G FQE Q + +
Sbjct: 62 TRLPAVCLVVSGPGLIHALAGAANAQVNGWPMVIVAGSSENGQQSYGAFQECDQWNMVKP 121
Query: 581 YCKYAAR 601
Y K+ A+
Sbjct: 122 YIKFGAK 128
>UniRef50_A4VE07 Cluster: 2-hydroxyphytanoyl-CoA lyase, putative;
n=1; Tetrahymena thermophila SB210|Rep:
2-hydroxyphytanoyl-CoA lyase, putative - Tetrahymena
thermophila SB210
Length = 405
Score = 147 bits (355), Expect = 3e-34
Identities = 63/134 (47%), Positives = 91/134 (67%)
Frame = +2
Query: 221 IDGNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYL 400
+ GN ++A +L +QG+E+ FGI+G+P+IE A Q+ G+ Y G RNEQ A Y+A A GYL
Sbjct: 1 MSGNLVVARALSRQGLEHCFGIIGVPIIELGFAIQAEGINYYGYRNEQGASYSAGAVGYL 60
Query: 401 TGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQVDSSRM 580
TGKPG+CL VSGPG+++ + G+ANA N WP+++I GS A G FQE Q+ ++
Sbjct: 61 TGKPGICLCVSGPGMINAVTGLANAWANGWPMILIVGSSDLAQNAKGAFQECDQISLTKP 120
Query: 581 YCKYAARPPSPRLI 622
Y K+A + S + I
Sbjct: 121 YVKFAVKITSAKQI 134
>UniRef50_Q9Y7M1 Cluster: Oxalyl-CoA decarboxylase; n=5;
Fungi/Metazoa group|Rep: Oxalyl-CoA decarboxylase -
Schizosaccharomyces pombe (Fission yeast)
Length = 568
Score = 142 bits (345), Expect = 5e-33
Identities = 65/136 (47%), Positives = 94/136 (69%)
Frame = +2
Query: 215 MGIDGNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATG 394
M I + ++A++L V+ VFGIVGIPVIE A Q++G++++G RNEQ+A YAA A G
Sbjct: 1 MSISFSELVAKTLLDLEVKVVFGIVGIPVIEICEAIQASGIRFVGFRNEQSAAYAATAYG 60
Query: 395 YLTGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQVDSS 574
YLT +PGVC+VV GPG++H + G+ N++ N WPL+++AGS + G FQE QV
Sbjct: 61 YLTQRPGVCVVVGGPGVVHAMAGVFNSKTNRWPLLLLAGSSETFQQNCGAFQELDQVSYL 120
Query: 575 RMYCKYAARPPSPRLI 622
+ K A RPPSP+++
Sbjct: 121 SPHTKLAVRPPSPKMV 136
>UniRef50_Q54DA9 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 580
Score = 135 bits (327), Expect = 7e-31
Identities = 57/123 (46%), Positives = 83/123 (67%)
Frame = +2
Query: 221 IDGNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYL 400
+DG I+A+S+K +E VFGIVG+P+ A Q+ G+ + G RNEQ+ YAA GYL
Sbjct: 1 MDGVEIIAKSIKNSAIEKVFGIVGVPITPIAYELQAQGVGFFGFRNEQSCSYAASIVGYL 60
Query: 401 TGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQVDSSRM 580
TG PG+C+ VSGPG++H + G+ NAQ N WP+++++ S + GGFQE Q +S+ +
Sbjct: 61 TGLPGLCMTVSGPGVVHALAGVLNAQSNGWPMILLSSSIDQSLVGKGGFQECKQFESAEL 120
Query: 581 YCK 589
YCK
Sbjct: 121 YCK 123
>UniRef50_Q9FNY6 Cluster: Oxalyl-CoA decarboxylase; n=13;
Magnoliophyta|Rep: Oxalyl-CoA decarboxylase -
Arabidopsis thaliana (Mouse-ear cress)
Length = 572
Score = 135 bits (326), Expect = 9e-31
Identities = 62/134 (46%), Positives = 88/134 (65%)
Frame = +2
Query: 221 IDGNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYL 400
IDGN ++A+SL GV ++FG+VGIPV A + G+++I NEQ+A YAA A GYL
Sbjct: 12 IDGNVLVAKSLSHLGVTHMFGVVGIPVTSLASRAMALGIRFIAFHNEQSAGYAASAYGYL 71
Query: 401 TGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQVDSSRM 580
TGKPG+ L VSGPG +H + G++N VN WPLV+I+GSC + G FQE Q+++ +
Sbjct: 72 TGKPGILLTVSGPGCVHGLAGLSNXWVNTWPLVMISGSCDQRDVGRGDFQELDQIEAVKA 131
Query: 581 YCKYAARPPSPRLI 622
+ K + + R I
Sbjct: 132 FSKLSEKAKDVREI 145
>UniRef50_P39994 Cluster: Uncharacterized protein YEL020C; n=3;
Saccharomycetales|Rep: Uncharacterized protein YEL020C -
Saccharomyces cerevisiae (Baker's yeast)
Length = 560
Score = 124 bits (300), Expect = 1e-27
Identities = 58/120 (48%), Positives = 80/120 (66%)
Frame = +2
Query: 242 AESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTGKPGVC 421
A+ L+K G++ VFGIVGIP+++ A + G+K+I RNEQAA YAA A GY++ KPGV
Sbjct: 10 AQLLQKYGIDTVFGIVGIPIVQLADTMVANGIKFIPCRNEQAASYAASAYGYISDKPGVL 69
Query: 422 LVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQVDSSRMYCKYAAR 601
L+V GPGL+H + G+ N+ N WPL+VIAGS + GGFQE QV + K+ +
Sbjct: 70 LIVGGPGLIHALAGIYNSMSNRWPLLVIAGSSSQSDIHKGGFQELDQVSLLSPFLKFTGK 129
>UniRef50_Q757R7 Cluster: AEL055Cp; n=1; Eremothecium gossypii|Rep:
AEL055Cp - Ashbya gossypii (Yeast) (Eremothecium
gossypii)
Length = 545
Score = 123 bits (296), Expect = 4e-27
Identities = 59/117 (50%), Positives = 80/117 (68%)
Frame = +2
Query: 215 MGIDGNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATG 394
MGI + +A +LK+ G+E VFGIVGIP++E A G+++I RNEQ+ YAA G
Sbjct: 1 MGIQVSDQIAIALKQHGIEVVFGIVGIPIVELAEKLAEHGVRFIACRNEQSCSYAASVYG 60
Query: 395 YLTGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQV 565
YLT KPG LVV G G++H + G+ NA VN WPL+VIAGS ++++ GGFQE Q+
Sbjct: 61 YLTNKPGALLVVGGSGVVHALAGIHNAWVNKWPLLVIAGSTEDEYK--GGFQELDQL 115
>UniRef50_A7TJH4 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 571
Score = 109 bits (263), Expect = 4e-23
Identities = 50/121 (41%), Positives = 73/121 (60%)
Frame = +2
Query: 239 LAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTGKPGV 418
+ + L K ++ +FGIVGIPV+E A +F + +++I RNEQ+A YAA GYL KPG+
Sbjct: 11 ITDILLKYDIDTIFGIVGIPVVELADSFIANNIRFISFRNEQSASYAASVYGYLNNKPGI 70
Query: 419 CLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQVDSSRMYCKYAA 598
L V GPGL+H + G+ N+ N WPL+V+ GS + GFQE V + + A
Sbjct: 71 LLTVGGPGLIHSLAGIYNSIENKWPLIVLTGSIESTDQYKHGFQELDHVSLLHRHINFTA 130
Query: 599 R 601
+
Sbjct: 131 K 131
>UniRef50_P40149 Cluster: Oxalyl-CoA decarboxylase; n=60;
Bacteria|Rep: Oxalyl-CoA decarboxylase - Oxalobacter
formigenes
Length = 568
Score = 107 bits (257), Expect = 2e-22
Identities = 48/128 (37%), Positives = 81/128 (63%), Gaps = 2/128 (1%)
Frame = +2
Query: 224 DGNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLT 403
DG +L ++LK ++ ++G+VGIP+ A +Q G ++ R+EQ A YAA GY+
Sbjct: 11 DGFHVLIDALKMNDIDTMYGVVGIPITNLARMWQDDGQRFYSFRHEQHAGYAASIAGYIE 70
Query: 404 GKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAI--GGFQEWPQVDSSR 577
GKPGVCL VS PG L+ + +A+A NC+P+++++GS + + G ++E Q++ +R
Sbjct: 71 GKPGVCLTVSAPGFLNGVTSLAHATTNCFPMILLSGSSEREIVDLQQGDYEEMDQMNVAR 130
Query: 578 MYCKYAAR 601
+CK + R
Sbjct: 131 PHCKASFR 138
>UniRef50_UPI0000383380 Cluster: COG0028: Thiamine
pyrophosphate-requiring enzymes [acetolactate synthase,
pyruvate dehydrogenase (cytochrome), glyoxylate
carboligase, phosphonopyruvate decarboxylase]; n=1;
Magnetospirillum magnetotacticum MS-1|Rep: COG0028:
Thiamine pyrophosphate-requiring enzymes [acetolactate
synthase, pyruvate dehydrogenase (cytochrome),
glyoxylate carboligase, phosphonopyruvate decarboxylase]
- Magnetospirillum magnetotacticum MS-1
Length = 298
Score = 103 bits (246), Expect = 5e-21
Identities = 48/128 (37%), Positives = 79/128 (61%), Gaps = 2/128 (1%)
Frame = +2
Query: 224 DGNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLT 403
DG ++ ++LK G+E ++G+ GIP+ + Q+ GL+ + R+EQ A AA G+LT
Sbjct: 25 DGFHLVIDALKLNGIETIYGVPGIPITDLGRMAQAEGLRVVSFRHEQNAGNAAAIAGFLT 84
Query: 404 GKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAI--GGFQEWPQVDSSR 577
KPG+CL VS PG L+ + +ANA NC+P+++I+GS + + G ++E Q+ ++
Sbjct: 85 KKPGICLTVSAPGFLNGLTALANATTNCFPMILISGSSEREIVDLQQGDYEEMDQLAIAK 144
Query: 578 MYCKYAAR 601
CK A R
Sbjct: 145 PLCKAAFR 152
>UniRef50_Q75PZ0 Cluster: Oxalyl-CoA decarboxylase; n=1;
Bifidobacterium animalis|Rep: Oxalyl-CoA decarboxylase -
Bifidobacterium animalis subsp. lactis (Bifidobacterium
lactis)
Length = 590
Score = 98.3 bits (234), Expect = 1e-19
Identities = 51/130 (39%), Positives = 81/130 (62%), Gaps = 4/130 (3%)
Frame = +2
Query: 224 DGNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLT 403
D LAE+L K GV++++G+VGIPV + A Q G+++IGMR+E+ A AA A G+LT
Sbjct: 17 DSPHYLAETLIKNGVKHMYGVVGIPVTDFARIAQGMGIRFIGMRHEEDAVNAAAAEGFLT 76
Query: 404 GKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCP----EDHEAIGGFQEWPQVDS 571
G+P V L VS PG L+ + + A N +P+++I GS + HE G ++ Q++
Sbjct: 77 GRPAVALTVSAPGFLNGLAPLLEATTNGFPVIMIGGSSTRHVVDMHE--GEYEGLDQMNY 134
Query: 572 SRMYCKYAAR 601
++ +CK + R
Sbjct: 135 AKQFCKESFR 144
>UniRef50_A7QY67 Cluster: Chromosome undetermined scaffold_240,
whole genome shotgun sequence; n=1; Vitis vinifera|Rep:
Chromosome undetermined scaffold_240, whole genome
shotgun sequence - Vitis vinifera (Grape)
Length = 214
Score = 97.9 bits (233), Expect = 2e-19
Identities = 49/127 (38%), Positives = 75/127 (59%)
Frame = +2
Query: 221 IDGNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYL 400
+DGN + A++ GV +FG+VGI V A S + ++ NEQ A YAA A GYL
Sbjct: 43 VDGNLLAAKAFAAAGVTLMFGVVGILVTSFAKRAVSILICFLAFHNEQWAGYAASAYGYL 102
Query: 401 TGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQVDSSRM 580
TGK + L+VSG G + + G++NA N W +V+I+GSC + G FQ+ +V +
Sbjct: 103 TGKADLLLIVSGHGCVQGLAGLSNATANAWSVVMISGSCNQADFGRGDFQKLDKVAAVEP 162
Query: 581 YCKYAAR 601
+ K++A+
Sbjct: 163 FSKFSAK 169
>UniRef50_UPI000150A350 Cluster: Thiamine pyrophosphate enzyme,
central domain containing protein; n=1; Tetrahymena
thermophila SB210|Rep: Thiamine pyrophosphate enzyme,
central domain containing protein - Tetrahymena
thermophila SB210
Length = 561
Score = 93.9 bits (223), Expect = 3e-18
Identities = 44/128 (34%), Positives = 77/128 (60%)
Frame = +2
Query: 227 GNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTG 406
G +LAE+L++QG+EY F + PVI+ +A + +K IG ++++ A +AA A G++TG
Sbjct: 20 GYNLLAEALQQQGLEYCFSVENSPVIQLEIALIANEIKNIGFKSQKGAVFAASAIGFMTG 79
Query: 407 KPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQVDSSRMYC 586
+PG+C+ ++ I G+ NA +N WP++VI+ ++A G QE + + Y
Sbjct: 80 RPGICVFGREYDIIQVIEGLTNAWINGWPVIVISACKDIYNQAKGTHQEIDRKAFKKFYI 139
Query: 587 KYAARPPS 610
KY+ + S
Sbjct: 140 KYSQKVTS 147
>UniRef50_A7H9A1 Cluster: Thiamine pyrophosphate protein central
region; n=1; Anaeromyxobacter sp. Fw109-5|Rep: Thiamine
pyrophosphate protein central region - Anaeromyxobacter
sp. Fw109-5
Length = 550
Score = 89.4 bits (212), Expect = 6e-17
Identities = 47/134 (35%), Positives = 72/134 (53%)
Frame = +2
Query: 221 IDGNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYL 400
+ G ++A L+K+GV F + G+ V G++ + R+EQAA +AA A L
Sbjct: 4 LTGGRLVARMLRKEGVTTAFTLSGLHVAPIYAGCVDEGIRLVDTRHEQAAAHAADAWARL 63
Query: 401 TGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQVDSSRM 580
T GV +V +GPG+ + G+ANA PLV++ G+ P ++ G QE PQV
Sbjct: 64 TRGVGVAIVTAGPGVTDAVTGVANAWAANVPLVLLGGAAPSFNQGRGSLQEMPQVQLFAG 123
Query: 581 YCKYAARPPSPRLI 622
K++ R PSP L+
Sbjct: 124 ITKWSDRIPSPELV 137
>UniRef50_Q9HKB0 Cluster: Acetolactate synthase, large chain related
protein; n=1; Thermoplasma acidophilum|Rep: Acetolactate
synthase, large chain related protein - Thermoplasma
acidophilum
Length = 553
Score = 87.8 bits (208), Expect = 2e-16
Identities = 46/122 (37%), Positives = 67/122 (54%)
Frame = +2
Query: 227 GNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTG 406
G I+AE L++ GVEYVF + G ++ A + +K + +R+EQ A +AA +
Sbjct: 10 GADIIAEYLERNGVEYVFTLTGHTILSLYEAIRKTKIKLVAVRHEQIAAHAADGYFRASH 69
Query: 407 KPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQVDSSRMYC 586
KPGV + GPGLL+ G+A A ++ PL+VI+G P +E G QE QV Y
Sbjct: 70 KPGVVITHIGPGLLNATTGVATAALDSSPLIVISGDAPSVYEGAGPHQEINQVTDLSQYL 129
Query: 587 KY 592
Y
Sbjct: 130 VY 131
>UniRef50_A0LEZ5 Cluster: Thiamine pyrophosphate enzyme TPP binding
domain protein; n=1; Syntrophobacter fumaroxidans
MPOB|Rep: Thiamine pyrophosphate enzyme TPP binding
domain protein - Syntrophobacter fumaroxidans (strain
DSM 10017 / MPOB)
Length = 568
Score = 85.8 bits (203), Expect = 7e-16
Identities = 44/126 (34%), Positives = 71/126 (56%)
Frame = +2
Query: 218 GIDGNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGY 397
G+ G ++A++L +GV+ +F + G V++ G++ I +R+EQ A +AA A
Sbjct: 23 GLTGGKLVAKTLATEGVQAIFTLCGAHVMDIYSGCLDEGIRIIDVRHEQTAAHAADAWTR 82
Query: 398 LTGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQVDSSR 577
LTG PGV +V +GPG+ + G+ANA P+++I G P + GG QE VD R
Sbjct: 83 LTGVPGVAVVTAGPGVTDAVTGVANAYRAQVPMLLIGGQAPIRNLLKGGLQEMNSVDMMR 142
Query: 578 MYCKYA 595
K++
Sbjct: 143 PITKFS 148
>UniRef50_P17597 Cluster: Acetolactate synthase, chloroplast
precursor; n=174; cellular organisms|Rep: Acetolactate
synthase, chloroplast precursor - Arabidopsis thaliana
(Mouse-ear cress)
Length = 670
Score = 85.0 bits (201), Expect = 1e-15
Identities = 45/123 (36%), Positives = 69/123 (56%), Gaps = 1/123 (0%)
Frame = +2
Query: 227 GNTILAESLKKQGVEYVFGIVGIPVIETAMAF-QSAGLKYIGMRNEQAACYAAQATGYLT 403
G IL E+L++QGVE VF G +E A +S+ ++ + R+EQ +AA+ +
Sbjct: 99 GADILVEALERQGVETVFAYPGGASMEIHQALTRSSSIRNVLPRHEQGGVFAAEGYARSS 158
Query: 404 GKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQVDSSRMY 583
GKPG+C+ SGPG + + G+A+A ++ PLV I G P FQE P V+ +R
Sbjct: 159 GKPGICIATSGPGATNLVSGLADALLDSVPLVAITGQVPRRMIGTDAFQETPIVEVTRSI 218
Query: 584 CKY 592
K+
Sbjct: 219 TKH 221
>UniRef50_A2SP25 Cluster: Acetolactate synthase-like TPP-requiring
enzyme; n=3; Proteobacteria|Rep: Acetolactate
synthase-like TPP-requiring enzyme - Methylibium
petroleiphilum (strain PM1)
Length = 586
Score = 84.2 bits (199), Expect = 2e-15
Identities = 42/120 (35%), Positives = 71/120 (59%)
Frame = +2
Query: 236 ILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTGKPG 415
++A LK V+ VFG+ G ++ M + G++ I +R+E+AA Y A A G L+GKPG
Sbjct: 14 VIARKLKALEVDRVFGLCGGHIMPIWMRLDAEGIRIIDVRDERAAVYMAHAYGELSGKPG 73
Query: 416 VCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQVDSSRMYCKYA 595
V LV +GPG+ + + G+ANA V+ P+++++G P + G Q+ V + ++A
Sbjct: 74 VALVTAGPGVTNAMTGIANAHVSRAPVMILSGVPPRPQLSRGALQDLDHVGMVKGITRFA 133
>UniRef50_Q2NGQ0 Cluster: Predicted thiamine pyrophosphate-requiring
enzyme; n=1; Methanosphaera stadtmanae DSM 3091|Rep:
Predicted thiamine pyrophosphate-requiring enzyme -
Methanosphaera stadtmanae (strain DSM 3091)
Length = 529
Score = 84.2 bits (199), Expect = 2e-15
Identities = 43/105 (40%), Positives = 63/105 (60%)
Frame = +2
Query: 239 LAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTGKPGV 418
L + L+ GVEYVFG G V+ A + + +K+I MR+EQAA +AA A +TGK GV
Sbjct: 11 LIDKLESNGVEYVFGYPGEQVLPIYEALRKSNIKHILMRHEQAAAHAADAYARITGKYGV 70
Query: 419 CLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQE 553
CL +GPG ++ + G++ A + PL+VI G D + FQ+
Sbjct: 71 CLATAGPGAMNLVMGVSAAYKDNVPLIVITGDVSSDVKGEDTFQD 115
>UniRef50_Q607C4 Cluster: Acetolactate synthase; n=1; Methylococcus
capsulatus|Rep: Acetolactate synthase - Methylococcus
capsulatus
Length = 553
Score = 83.4 bits (197), Expect = 4e-15
Identities = 41/98 (41%), Positives = 59/98 (60%)
Frame = +2
Query: 227 GNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTG 406
G +L +SL+ GVEYVFG+ G ++ G ++I R+E A + AQ+ G +TG
Sbjct: 10 GADLLVDSLQALGVEYVFGVPGGAILPILNVLADRGPRFIVCRDETGAAFMAQSWGRITG 69
Query: 407 KPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCP 520
+PGV L SGPGL++ + G+A A + PLVVI G P
Sbjct: 70 RPGVVLTTSGPGLINAVCGVATATEDRDPLVVITGQVP 107
>UniRef50_Q03UU2 Cluster: Acetolactate synthase; n=2; Leuconostoc
mesenteroides|Rep: Acetolactate synthase - Leuconostoc
mesenteroides subsp. mesenteroides (strain ATCC 8293
/NCDO 523)
Length = 570
Score = 82.2 bits (194), Expect = 9e-15
Identities = 49/113 (43%), Positives = 68/113 (60%), Gaps = 1/113 (0%)
Frame = +2
Query: 218 GIDGNTILAESLKKQGVEYVFGIVGIPVIETAMA-FQSAGLKYIGMRNEQAACYAAQATG 394
G +G IL +SL+K GV +FG G VI A ++S+ +K+I +R+EQAA +AA+
Sbjct: 9 GKNGAHILLDSLEKAGVNSLFGYPGGAVIPLYDALYESSHIKHILVRHEQAAAHAAEGYA 68
Query: 395 YLTGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQE 553
TGKPGV LV SGPG + + G+A+A + PLVVI+G FQE
Sbjct: 69 KATGKPGVVLVTSGPGATNTVTGIADAFCDSVPLVVISGQVGSAAIGSDAFQE 121
>UniRef50_A7QYX6 Cluster: Chromosome chr16 scaffold_258, whole
genome shotgun sequence; n=6; Vitis vinifera|Rep:
Chromosome chr16 scaffold_258, whole genome shotgun
sequence - Vitis vinifera (Grape)
Length = 866
Score = 82.2 bits (194), Expect = 9e-15
Identities = 46/124 (37%), Positives = 70/124 (56%), Gaps = 2/124 (1%)
Frame = +2
Query: 227 GNTILAESLKKQGVEYVFGIVGIPV--IETAMAFQSAGLKYIGMRNEQAACYAAQATGYL 400
G+ IL E+L+++GV +VFG G I A+A +S+ ++ + R+EQ +AA
Sbjct: 302 GSDILVEALEREGVTHVFGYPGGASMGIHEALA-RSSMIRNVLPRHEQGGIFAADGYARA 360
Query: 401 TGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQVDSSRM 580
+G+PGVCL SGPG + I G+A+A + P+V I G P FQE P +D +R
Sbjct: 361 SGRPGVCLTSSGPGATNIISGIADANFDSIPIVAITGQVPRGLMGTDAFQEVPLIDITRP 420
Query: 581 YCKY 592
K+
Sbjct: 421 ITKF 424
>UniRef50_Q6L042 Cluster: Acetolactate synthase; n=6; Archaea|Rep:
Acetolactate synthase - Picrophilus torridus
Length = 573
Score = 81.4 bits (192), Expect = 2e-14
Identities = 46/113 (40%), Positives = 65/113 (57%), Gaps = 4/113 (3%)
Frame = +2
Query: 227 GNTILAESLKKQGVEYVFGIVGI---PVIETAMA-FQSAGLKYIGMRNEQAACYAAQATG 394
G+ ++ ESLKKQGV+ +FGI G+ PV + + +S L++I MR+EQAA +AA A
Sbjct: 2 GSRLIVESLKKQGVKDIFGIPGLYNMPVYDAFLEDVESGQLRHILMRHEQAAAHAADAYA 61
Query: 395 YLTGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQE 553
TG PGVC SGPG+ + + G+ A + P+V I G FQE
Sbjct: 62 RATGFPGVCTATSGPGVTNLVTGLITAYQDSSPVVAITGQVNSSSIGKMSFQE 114
>UniRef50_Q7U5G1 Cluster: Acetolactate synthase large subunit; n=60;
cellular organisms|Rep: Acetolactate synthase large
subunit - Synechococcus sp. (strain WH8102)
Length = 617
Score = 81.4 bits (192), Expect = 2e-14
Identities = 45/120 (37%), Positives = 66/120 (55%), Gaps = 4/120 (3%)
Frame = +2
Query: 206 NGSMGIDGNTILAESLKKQGVEYVFGIVG---IPVIETAMAFQSAG-LKYIGMRNEQAAC 373
N I G L ++L++ GV+ +FG G +P+ + +S G +K+I +R+EQA
Sbjct: 16 NAPQTISGAAALMDALRRHGVDTIFGYPGGAILPIYDALHIAESEGWVKHILVRHEQAGT 75
Query: 374 YAAQATGYLTGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQE 553
+AA A TGK GVC SGPG + + G+A AQ++ P+VVI G P FQE
Sbjct: 76 HAADAYARATGKVGVCFGTSGPGATNLVTGIATAQMDSVPMVVITGQVPRPAIGTDAFQE 135
>UniRef50_UPI0001597788 Cluster: IlvB; n=1; Bacillus
amyloliquefaciens FZB42|Rep: IlvB - Bacillus
amyloliquefaciens FZB42
Length = 597
Score = 80.2 bits (189), Expect = 4e-14
Identities = 42/111 (37%), Positives = 62/111 (55%)
Frame = +2
Query: 221 IDGNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYL 400
++G +L ESLKK+ VE +FG G V+ +GL +I R+EQ A +AA+ +
Sbjct: 41 MNGALMLIESLKKENVEMIFGYPGGAVLPIYDKLYQSGLVHILPRHEQGAIHAAEGYARI 100
Query: 401 TGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQE 553
+GKPGV + SGPG + + G+A+A ++ PLVV G FQE
Sbjct: 101 SGKPGVVIATSGPGATNLVTGLADAMIDSLPLVVFTGQVATSVIGSDAFQE 151
>UniRef50_A4ABB6 Cluster: Pyruvate decarboxylase; n=2;
Proteobacteria|Rep: Pyruvate decarboxylase -
Congregibacter litoralis KT71
Length = 565
Score = 79.8 bits (188), Expect = 5e-14
Identities = 40/123 (32%), Positives = 67/123 (54%)
Frame = +2
Query: 221 IDGNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYL 400
+ G +A+ LK + V+ V+G++G + A G+ ++ R+E AA Y A A L
Sbjct: 1 MSGAEAIAKFLKARRVKRVYGVIGGHIQPICDALVRIGIDFVDTRHECAAVYMAHAEARL 60
Query: 401 TGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQVDSSRM 580
TG GV + +GPG+ + + G+ANA V P++VI+G P + + Q+ PQ + R
Sbjct: 61 TGNFGVIMATAGPGVTNAVTGIANADVARVPVLVISGRVPRPQDGMSSMQDIPQAEIVRP 120
Query: 581 YCK 589
C+
Sbjct: 121 LCR 123
>UniRef50_Q6AJI2 Cluster: Acetolactate synthase; n=42; cellular
organisms|Rep: Acetolactate synthase - Desulfotalea
psychrophila
Length = 612
Score = 79.4 bits (187), Expect = 6e-14
Identities = 48/131 (36%), Positives = 74/131 (56%), Gaps = 2/131 (1%)
Frame = +2
Query: 206 NGSMG-IDGNTILAESLKKQGVEYVFGIVGIPVIETAMAFQ-SAGLKYIGMRNEQAACYA 379
NG MG I G+ + + LK++GV+ +FG G VI+ A S ++++ +R+EQ A +A
Sbjct: 43 NGLMGKITGSRAIVQCLKEEGVQTIFGYPGGAVIDLYDALMDSTDIEHVLVRHEQGAVHA 102
Query: 380 AQATGYLTGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWP 559
A A +TG+ GV L+ SGPG + + G+A A ++ PLVV+ G P FQE
Sbjct: 103 ADAFARVTGEVGVALLTSGPGATNGVTGIATAYLDSIPLVVLTGQVPRALIGNDAFQEVD 162
Query: 560 QVDSSRMYCKY 592
V +R K+
Sbjct: 163 IVGITRPCTKH 173
>UniRef50_A6G0J0 Cluster: Thiamine pyrophosphate enzyme-like TPP
binding protein; n=2; Proteobacteria|Rep: Thiamine
pyrophosphate enzyme-like TPP binding protein -
Plesiocystis pacifica SIR-1
Length = 941
Score = 79.0 bits (186), Expect = 8e-14
Identities = 41/114 (35%), Positives = 64/114 (56%), Gaps = 4/114 (3%)
Frame = +2
Query: 224 DGNTILAESLKKQGVEYVFGIVGIPVIETAMAF----QSAGLKYIGMRNEQAACYAAQAT 391
D + ++AE+L GV +VFG+VG + A A ++ L Y+G+R+E AA +A A
Sbjct: 400 DASDVIAETLTNWGVRWVFGMVGHSNLGLADALRRRTETGELGYVGIRHEGAAAFAVSAY 459
Query: 392 GYLTGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQE 553
G LTG+P CL ++GPG + + G+ +A V+ P + + G G FQE
Sbjct: 460 GKLTGRPAACLAIAGPGATNLLTGLWDANVDRAPAIALTGQVQSQVLGRGAFQE 513
>UniRef50_Q8U2A4 Cluster: Acetolactate synthase; n=4; cellular
organisms|Rep: Acetolactate synthase - Pyrococcus
furiosus
Length = 564
Score = 79.0 bits (186), Expect = 8e-14
Identities = 40/136 (29%), Positives = 72/136 (52%)
Frame = +2
Query: 215 MGIDGNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATG 394
M + G L +L+K+GV++ FGI+G ++ + +++I R+EQ A +AA
Sbjct: 1 MEMSGAKALVRALEKEGVQHTFGIIGGSIMPVFDELLDSNIRHITTRHEQGAAHAADGYA 60
Query: 395 YLTGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQVDSS 574
++G+PGV + SGPG + + G+A A ++ P+V + G P FQE ++ +
Sbjct: 61 RVSGRPGVAITTSGPGATNLVTGIATAYMDSSPIVALTGQVPTYMVGKMAFQETDIINIT 120
Query: 575 RMYCKYAARPPSPRLI 622
+ K+ + PR I
Sbjct: 121 KPITKWNYQVKRPREI 136
>UniRef50_Q12ZE1 Cluster: Thiamine pyrophosphate requiring enzyme;
n=1; Methanococcoides burtonii DSM 6242|Rep: Thiamine
pyrophosphate requiring enzyme - Methanococcoides
burtonii (strain DSM 6242)
Length = 544
Score = 79.0 bits (186), Expect = 8e-14
Identities = 35/95 (36%), Positives = 60/95 (63%)
Frame = +2
Query: 227 GNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTG 406
G+ + + L+ +GV+Y+FGI G ++ + + +++I +R+EQ+A + A G LTG
Sbjct: 3 GSELFVKCLENEGVKYIFGIPGEETLDLMESLSRSDIEFIVVRHEQSAAFMADVCGRLTG 62
Query: 407 KPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAG 511
+PGVCL GPG + + G+A+A ++ PLV I G
Sbjct: 63 RPGVCLPTLGPGATNLMTGVADAHLDRAPLVAITG 97
>UniRef50_Q8A609 Cluster: Acetolactate synthase; n=30; Bacteria|Rep:
Acetolactate synthase - Bacteroides thetaiotaomicron
Length = 565
Score = 78.6 bits (185), Expect = 1e-13
Identities = 47/127 (37%), Positives = 69/127 (54%), Gaps = 2/127 (1%)
Frame = +2
Query: 221 IDGNTILAESLKKQGVEYVFGIVGIPVIET--AMAFQSAGLKYIGMRNEQAACYAAQATG 394
I G + SL+ QGV +FG G ++ T A+ L +I +R+EQ A +AAQ
Sbjct: 6 ITGAEAMMRSLEHQGVTTIFGYPGGSIMPTFDALYDHQNTLNHILVRHEQGAAHAAQGYA 65
Query: 395 YLTGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQVDSS 574
++GK GVCLV SGPG + I G+A+A ++ P+VVIAG FQE V +
Sbjct: 66 RVSGKVGVCLVTSGPGATNTITGIADAMIDSTPIVVIAGQVGTGFLGTDAFQEVDLVGIT 125
Query: 575 RMYCKYA 595
+ K++
Sbjct: 126 QPIAKWS 132
>UniRef50_A4AC84 Cluster: Acetolactate synthase; n=2; cellular
organisms|Rep: Acetolactate synthase - Congregibacter
litoralis KT71
Length = 619
Score = 78.6 bits (185), Expect = 1e-13
Identities = 42/113 (37%), Positives = 61/113 (53%)
Frame = +2
Query: 215 MGIDGNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATG 394
+ + G ILA+ L +GV+ +FG G +E G++ I +EQ A +AAQ
Sbjct: 30 VALRGAQILAKCLVAEGVDTLFGYPGGANLEIFDVLPQFGIRCIRTEHEQGAVHAAQGYA 89
Query: 395 YLTGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQE 553
+TG+PGVCL SGPG + + G+A+A + PLV I G+ P FQE
Sbjct: 90 RVTGRPGVCLATSGPGATNLVTGIADANSDSTPLVAITGNVPSHLLGKNAFQE 142
>UniRef50_Q67QP4 Cluster: Acetolactate synthase-like TPP-requiring
enzyme; n=1; Symbiobacterium thermophilum|Rep:
Acetolactate synthase-like TPP-requiring enzyme -
Symbiobacterium thermophilum
Length = 551
Score = 78.2 bits (184), Expect = 1e-13
Identities = 39/106 (36%), Positives = 61/106 (57%)
Frame = +2
Query: 236 ILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTGKPG 415
++A +L+ +GVE VF + G V+ G++ + +R+EQ A +AA A LTG+PG
Sbjct: 15 LVARALRNEGVEVVFTLCGGHVMSIYDGCLDEGIRVVDVRHEQTAAFAADAWSRLTGRPG 74
Query: 416 VCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQE 553
V ++ +GPG+ + + G+ANA P+VVI G P G QE
Sbjct: 75 VAILTAGPGVTNAVTGIANAYRAQSPMVVIGGQGPRSLAGKGALQE 120
>UniRef50_A5ZR04 Cluster: Acetolactate synthase; n=3;
Clostridiales|Rep: Acetolactate synthase - Ruminococcus
obeum ATCC 29174
Length = 594
Score = 78.2 bits (184), Expect = 1e-13
Identities = 46/125 (36%), Positives = 65/125 (52%), Gaps = 1/125 (0%)
Frame = +2
Query: 221 IDGNTILAESLKKQGVEYVFGIVGIPVIETA-MAFQSAGLKYIGMRNEQAACYAAQATGY 397
I GN +L ++LK++GV +FG G I+ + ++ +G+ I R+EQA + A A
Sbjct: 26 ISGNKLLVKALKEEGVTTLFGYPGACTIDISDELYRQSGIDIILPRHEQALVHEADAYAR 85
Query: 398 LTGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQVDSSR 577
TGK GVCLV SGPG + + G+A A + PLV G FQE V +R
Sbjct: 86 TTGKVGVCLVTSGPGATNLVTGLATANYDSVPLVCFTGQVARHLIGNDAFQEVDIVGITR 145
Query: 578 MYCKY 592
KY
Sbjct: 146 SITKY 150
>UniRef50_A7DN45 Cluster: Acetolactate synthase, large subunit,
biosynthetic type; n=1; Candidatus Nitrosopumilus
maritimus SCM1|Rep: Acetolactate synthase, large
subunit, biosynthetic type - Candidatus Nitrosopumilus
maritimus SCM1
Length = 566
Score = 77.8 bits (183), Expect = 2e-13
Identities = 41/126 (32%), Positives = 65/126 (51%)
Frame = +2
Query: 227 GNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTG 406
G L +++K+GV+ VFG+ G + F +++I R+EQ+A + A G ++
Sbjct: 9 GAKALMTAMEKEGVKEVFGLPGGANLPMYDEFARCDIRHILARHEQSAAHMADGFGRVSR 68
Query: 407 KPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQVDSSRMYC 586
KPGVC SGPG + + G+A AQ + P+V + G P FQE + +
Sbjct: 69 KPGVCFATSGPGATNILTGIATAQADSAPMVAVTGQVPTPMIGKDAFQESDIIGMANPVV 128
Query: 587 KYAARP 604
KYA +P
Sbjct: 129 KYAFQP 134
>UniRef50_Q3IXG3 Cluster: Thiamine pyrophosphate-requiring enzyme;
n=4; Proteobacteria|Rep: Thiamine
pyrophosphate-requiring enzyme - Rhodobacter sphaeroides
(strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM158)
Length = 550
Score = 77.0 bits (181), Expect = 3e-13
Identities = 38/125 (30%), Positives = 71/125 (56%)
Frame = +2
Query: 227 GNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTG 406
G +L +L GV +F + G ++ A +G++ + +R+E AA + A+ LTG
Sbjct: 11 GADLLVSTLVDCGVTRIFSLSGNQIMPLYDACLGSGIEIVHVRHEAAAVFMAEGWAQLTG 70
Query: 407 KPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQVDSSRMYC 586
+ GV LV +GPG + +G + +A+ + PL++++G P + +G FQ QV ++ +
Sbjct: 71 EVGVALVTAGPGAANAVGPLMSARQSETPLLLLSGDSPRAQDGMGAFQTLDQVAATAPFT 130
Query: 587 KYAAR 601
K++AR
Sbjct: 131 KHSAR 135
>UniRef50_Q9X5G0 Cluster: Acetolactate synthase; n=57; Bacteria|Rep:
Acetolactate synthase - Zymomonas mobilis
Length = 611
Score = 77.0 bits (181), Expect = 3e-13
Identities = 46/127 (36%), Positives = 68/127 (53%), Gaps = 3/127 (2%)
Frame = +2
Query: 236 ILAESLKKQGVEYVFGIVGIPVIETAMA-FQSAGLKYIGMRNEQAACYAAQATGYLTGKP 412
I+ E+LK GV+ +FG G V+ A +Q G+++I R E A +AA+ TGKP
Sbjct: 26 IVLETLKDMGVDLIFGYPGGAVLPIYDALYQDEGIRHILARQEGGAVHAAEGYARSTGKP 85
Query: 413 GVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQVDSSRMYCK- 589
GV +V SGPG + + G+A+A ++ PLVV +G + FQE + +R K
Sbjct: 86 GVVIVTSGPGATNAVTGIADAMLDSIPLVVFSGQVATNLIGTDAFQEADTIGITRHCTKH 145
Query: 590 -YAARPP 607
Y R P
Sbjct: 146 NYLVRDP 152
>UniRef50_A3H9A0 Cluster: Thiamine pyrophosphate enzyme-like
TPP-binding; n=1; Caldivirga maquilingensis IC-167|Rep:
Thiamine pyrophosphate enzyme-like TPP-binding -
Caldivirga maquilingensis IC-167
Length = 595
Score = 77.0 bits (181), Expect = 3e-13
Identities = 37/109 (33%), Positives = 62/109 (56%)
Frame = +2
Query: 227 GNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTG 406
G+ ++ + L++Q VEYVF + G +++ A S + I +R+E A Y A +T
Sbjct: 7 GSEVIVKYLERQKVEYVFTLTGHTIVDLYDALYSPDINLIQVRHEAVAAYMADGYFRVTH 66
Query: 407 KPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQE 553
KPGV + GPGLL+ + +ANA ++ +++I+G P +E G QE
Sbjct: 67 KPGVVVTHVGPGLLNAVPAVANAALDSSAMIIISGDAPSIYEGAGAHQE 115
>UniRef50_O68497 Cluster: Catabolic acetolactate synthase; n=11;
Bacteria|Rep: Catabolic acetolactate synthase -
Clostridium acetobutylicum
Length = 563
Score = 76.6 bits (180), Expect = 5e-13
Identities = 38/105 (36%), Positives = 58/105 (55%)
Frame = +2
Query: 236 ILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTGKPG 415
++ + L+ + VEY+FGI G + A + +K+I R+EQ A + A G LTG+PG
Sbjct: 28 LVVKCLENENVEYIFGIPGEENLALIKALTKSPIKFITTRHEQGAAFMADVYGRLTGRPG 87
Query: 416 VCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQ 550
VCL GPG + + G+A+A ++ PL+ I G D I Q
Sbjct: 88 VCLSTLGPGATNLMTGVADANLDGAPLIAITGQVGTDRMHIESHQ 132
>UniRef50_A1ICC6 Cluster: Putative TPP-requiring enzyme; n=1;
Candidatus Desulfococcus oleovorans Hxd3|Rep: Putative
TPP-requiring enzyme - Candidatus Desulfococcus
oleovorans Hxd3
Length = 557
Score = 76.6 bits (180), Expect = 5e-13
Identities = 45/130 (34%), Positives = 67/130 (51%), Gaps = 1/130 (0%)
Frame = +2
Query: 212 SMGIDGNTILAESLKK-QGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQA 388
S I G + A+ +K+ + V+ +F I G + G++ I +R+EQAA A A
Sbjct: 2 SKKITGGHLAAKYMKQMEQVDTIFTISGGHIENLLDGLSEYGIRTIDVRHEQAAAMMAHA 61
Query: 389 TGYLTGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQVD 568
+PGVCLV +GPG + I G+ANA + PLVV+ G P + G QE Q+D
Sbjct: 62 WSVYRNEPGVCLVTAGPGFTNAITGIANAHLENVPLVVLCGRHPIRDDLKGALQEMNQID 121
Query: 569 SSRMYCKYAA 598
+ K+ A
Sbjct: 122 MVKPVTKWCA 131
>UniRef50_Q04789 Cluster: Acetolactate synthase; n=69; Bacteria|Rep:
Acetolactate synthase - Bacillus subtilis
Length = 571
Score = 76.6 bits (180), Expect = 5e-13
Identities = 41/96 (42%), Positives = 55/96 (57%)
Frame = +2
Query: 227 GNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTG 406
G ++ + L +QGV +VFGI G + A Q G + I R+EQ A + AQA G LTG
Sbjct: 17 GAELVVDCLVEQGVTHVFGIPGAKIDAVFDALQDKGPEIIVARHEQNAAFMAQAVGRLTG 76
Query: 407 KPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGS 514
KPGV LV SGPG + G+ A P+V +AG+
Sbjct: 77 KPGVVLVTSGPGASNLATGLLTANTEGDPVVALAGN 112
>UniRef50_Q9WZ18 Cluster: Acetolactate synthase; n=7; cellular
organisms|Rep: Acetolactate synthase - Thermotoga
maritima
Length = 584
Score = 76.2 bits (179), Expect = 6e-13
Identities = 41/111 (36%), Positives = 61/111 (54%), Gaps = 2/111 (1%)
Frame = +2
Query: 227 GNTILAESLKKQGVEYVFGIVGIPVIET--AMAFQSAGLKYIGMRNEQAACYAAQATGYL 400
G+ +L E+L K+GV+ +FGI G +I + + + R+EQ A +AA +
Sbjct: 8 GSKMLFEALLKEGVDTIFGIPGGAIINVYDELCNYEDKINFYLFRHEQGATHAADGYARV 67
Query: 401 TGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQE 553
TGKPGV +V SGPG + + G+A A ++ P+VVI G P FQE
Sbjct: 68 TGKPGVVIVTSGPGATNTVTGIATAYMDSIPIVVITGQVPTSFIGTDAFQE 118
>UniRef50_Q89N19 Cluster: Blr4023 protein; n=72; Bacteria|Rep:
Blr4023 protein - Bradyrhizobium japonicum
Length = 554
Score = 76.2 bits (179), Expect = 6e-13
Identities = 35/100 (35%), Positives = 59/100 (59%)
Frame = +2
Query: 221 IDGNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYL 400
+ G+ + +L+ +GV+ +FG+ G ++ + +++ ++ I R+EQAA + A G L
Sbjct: 8 VKGSDLFVAALENEGVDRIFGVPGEENLDLVESLRTSKIELILTRHEQAAAFMAATHGRL 67
Query: 401 TGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCP 520
TGKPGVCL GPG L+ G A A + P+++I G P
Sbjct: 68 TGKPGVCLSTLGPGALNLSTGAAYAHLGAMPMILITGQKP 107
>UniRef50_Q5LKS2 Cluster: Sulphoacetaldehyde acetyltransferase,
putative; n=1; Silicibacter pomeroyi|Rep:
Sulphoacetaldehyde acetyltransferase, putative -
Silicibacter pomeroyi
Length = 559
Score = 76.2 bits (179), Expect = 6e-13
Identities = 46/133 (34%), Positives = 71/133 (53%), Gaps = 2/133 (1%)
Frame = +2
Query: 221 IDGNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAG-LKYIGMRNEQAACYAAQATGY 397
I+G + LK G++ VFG++G ++E A + Y+G R+E+AA + A A
Sbjct: 4 INGGEAVYRVLKANGIDTVFGLLGGSMLELYDAMHKGREIAYVGARDERAAGHMADAWAR 63
Query: 398 LTGKPGVCL-VVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQVDSS 574
+TGKPGV L +GPG+++ + +A A + P+VVIAG+ +A FQE QV
Sbjct: 64 MTGKPGVVLGAQAGPGVVNIVTAVAEAHLAYSPMVVIAGAITRADQAKDTFQEVDQVALF 123
Query: 575 RMYCKYAARPPSP 613
CK + P
Sbjct: 124 APICKRSVMVTDP 136
>UniRef50_Q3AM88 Cluster: Alpha-acetolactate synthase; RBL02971;
n=2; Synechococcus|Rep: Alpha-acetolactate synthase;
RBL02971 - Synechococcus sp. (strain CC9605)
Length = 548
Score = 76.2 bits (179), Expect = 6e-13
Identities = 39/102 (38%), Positives = 58/102 (56%)
Frame = +2
Query: 221 IDGNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYL 400
++G L ++L+ GV +VFGI G V A + ++ + R+EQ A + AQA G L
Sbjct: 1 MNGAEFLVKALEAHGVTHVFGIPGAKVDSVFTALLDSPIELVLCRHEQNAAFMAQAFGRL 60
Query: 401 TGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPED 526
TG+ GVCL SGPG+ + + G+A A P++ I G P D
Sbjct: 61 TGRIGVCLATSGPGVTNLVTGLATATTEGDPVLAIGGEVPLD 102
>UniRef50_Q1ARE6 Cluster: Acetolactate synthase; n=4; Bacteria|Rep:
Acetolactate synthase - Rubrobacter xylanophilus (strain
DSM 9941 / NBRC 16129)
Length = 564
Score = 76.2 bits (179), Expect = 6e-13
Identities = 39/109 (35%), Positives = 60/109 (55%)
Frame = +2
Query: 227 GNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTG 406
G+ + E+L +GVEY+FG G ++ A L+++ +R+EQAA +AA TG
Sbjct: 15 GSEAMCEALLDEGVEYLFGYPGGAIMPFYDALPDYPLRHVLVRHEQAAAHAADGYARATG 74
Query: 407 KPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQE 553
+ GVC+ SGPG + + G+A AQ++ P+V I G FQE
Sbjct: 75 RVGVCVATSGPGATNLVTGLATAQMDSVPVVAITGQVGRGAMGKDSFQE 123
>UniRef50_Q18S72 Cluster: Thiamine pyrophosphate enzyme-like TPP
binding region; n=2; Desulfitobacterium hafniense|Rep:
Thiamine pyrophosphate enzyme-like TPP binding region -
Desulfitobacterium hafniense (strain DCB-2)
Length = 591
Score = 76.2 bits (179), Expect = 6e-13
Identities = 42/129 (32%), Positives = 64/129 (49%)
Frame = +2
Query: 209 GSMGIDGNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQA 388
G + + G LA L K+GV ++GI G ++ A + ++ +R+EQAA + A
Sbjct: 20 GRVRMTGAQFLAAFLAKKGVSQIYGIPGAAILPFYDAVRELNMESYNVRHEQAAIFMADG 79
Query: 389 TGYLTGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQVD 568
TGK GVC SGPG + + G+ +A + PL+ + G P FQE P V+
Sbjct: 80 YSRATGKVGVCAATSGPGATNFLTGLYSAYSDSVPLLALTGQVPTSLIGKDSFQEAPMVE 139
Query: 569 SSRMYCKYA 595
+R K A
Sbjct: 140 MARPVTKAA 148
>UniRef50_Q5V522 Cluster: Acetolactate synthase; n=4; cellular
organisms|Rep: Acetolactate synthase - Haloarcula
marismortui (Halobacterium marismortui)
Length = 585
Score = 76.2 bits (179), Expect = 6e-13
Identities = 35/109 (32%), Positives = 59/109 (54%)
Frame = +2
Query: 227 GNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTG 406
G + +L+ +YVFG+ G ++ A + + ++ M +EQ A +AA A G +TG
Sbjct: 26 GAQSVIRALENAETDYVFGVQGGAIMPVYDALYDSDINHVTMAHEQGASHAADAYGVVTG 85
Query: 407 KPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQE 553
PGVC SGPG + + G+A+A ++ P++ + G P + FQE
Sbjct: 86 DPGVCFATSGPGATNLVTGIADANMDSDPVIALTGQVPTEFVGNDAFQE 134
>UniRef50_P73918 Cluster: Acetolactate synthase; n=6; Bacteria|Rep:
Acetolactate synthase - Synechocystis sp. (strain PCC
6803)
Length = 550
Score = 75.8 bits (178), Expect = 8e-13
Identities = 38/105 (36%), Positives = 59/105 (56%)
Frame = +2
Query: 236 ILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTGKPG 415
+L + L+ + VEY+FG+ G + A +++ +++I R+EQ A + A G LTGK G
Sbjct: 9 LLVQCLENEDVEYIFGVPGEENLHILEALKNSPIRFITTRHEQGAAFMADVYGRLTGKAG 68
Query: 416 VCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQ 550
VCL GPG + + G+A+A ++ PLV I G D I Q
Sbjct: 69 VCLSTLGPGATNLMTGVADANLDGAPLVAITGQVGTDRMHIESHQ 113
>UniRef50_A3DID9 Cluster: Acetolactate synthase; n=3;
Clostridium|Rep: Acetolactate synthase - Clostridium
thermocellum (strain ATCC 27405 / DSM 1237)
Length = 542
Score = 75.4 bits (177), Expect = 1e-12
Identities = 41/126 (32%), Positives = 66/126 (52%)
Frame = +2
Query: 215 MGIDGNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATG 394
M + G + ++L+ +GVE VFG G + A + +++I R+EQ A +AA
Sbjct: 1 MKLSGAQAIVKALELEGVEVVFGYPGAAICPFYDALMESKIRHILTRHEQGAAHAASGYA 60
Query: 395 YLTGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQVDSS 574
TG+ GVC+ SGPG + I G+A+A ++ PLV I G + FQE ++
Sbjct: 61 RTTGRVGVCVATSGPGATNLITGIADAYMDSIPLVAITGQVNSELIGRDVFQEADITGAT 120
Query: 575 RMYCKY 592
+CK+
Sbjct: 121 DPFCKH 126
>UniRef50_Q8TR30 Cluster: Acetolactate synthase, large subunit; n=4;
cellular organisms|Rep: Acetolactate synthase, large
subunit - Methanosarcina acetivorans
Length = 548
Score = 75.4 bits (177), Expect = 1e-12
Identities = 37/92 (40%), Positives = 56/92 (60%)
Frame = +2
Query: 236 ILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTGKPG 415
+ LK++GVEY+FG+ G + + +++ +K I R+EQAA + A A G LTGK G
Sbjct: 10 LFVTQLKEEGVEYIFGLPGEENLALLESLRNSNIKLIITRHEQAAAFMAAAYGRLTGKAG 69
Query: 416 VCLVVSGPGLLHCIGGMANAQVNCWPLVVIAG 511
VC GPG + + G+A AQ+ PL+ I+G
Sbjct: 70 VCFSTLGPGATNLVTGVAQAQLIGAPLISISG 101
>UniRef50_A7D3B0 Cluster: Acetolactate synthase, large subunit,
biosynthetic type; n=1; Halorubrum lacusprofundi ATCC
49239|Rep: Acetolactate synthase, large subunit,
biosynthetic type - Halorubrum lacusprofundi ATCC 49239
Length = 608
Score = 75.4 bits (177), Expect = 1e-12
Identities = 37/130 (28%), Positives = 69/130 (53%)
Frame = +2
Query: 203 LNGSMGIDGNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAA 382
+ G + +++A +L+ G E FG+ G ++ A + ++++ M +EQ A +AA
Sbjct: 40 VTGPVSTGAESVVA-ALEAAGAETAFGVQGGAIMPVYDALYDSSIRHVTMAHEQGAAHAA 98
Query: 383 QATGYLTGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQ 562
A G + G+PG+CL SGPG + + G+A+A ++ ++ + G P + FQE
Sbjct: 99 DAYGVVAGEPGLCLATSGPGATNLVTGIADADMDSDAMLALTGQVPTEFVGNDAFQETDT 158
Query: 563 VDSSRMYCKY 592
V +R K+
Sbjct: 159 VGVTRPITKH 168
>UniRef50_Q1LF51 Cluster: Thiamine pyrophosphate enzyme-like TPP
binding region; n=3; Bacteria|Rep: Thiamine
pyrophosphate enzyme-like TPP binding region - Ralstonia
metallidurans (strain CH34 / ATCC 43123 / DSM 2839)
Length = 640
Score = 74.1 bits (174), Expect = 2e-12
Identities = 42/140 (30%), Positives = 69/140 (49%)
Frame = +2
Query: 191 VSQKLNGSMGIDGNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAA 370
+ QK + I G ++A +LK +GV+ +F + G +I+ G++ I +R+EQ A
Sbjct: 74 LKQKSRDAGVISGGHLVARALKNEGVDTIFTLCGGHIIDIYDGCVDEGIRIIDVRHEQVA 133
Query: 371 CYAAQATGYLTGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQ 550
+AA TGK + +GPG + + G+A A + P++ I G +G Q
Sbjct: 134 AHAADGYARQTGKLACVVTTAGPGCTNAVTGVATAFRSESPIIHIGGQGALSQHKMGSLQ 193
Query: 551 EWPQVDSSRMYCKYAARPPS 610
+ P VD K+AA PS
Sbjct: 194 DLPHVDMMAPITKFAATIPS 213
>UniRef50_A1HPN8 Cluster: Acetolactate synthase, large subunit,
biosynthetic type; n=2; Acidaminococcaceae|Rep:
Acetolactate synthase, large subunit, biosynthetic type
- Thermosinus carboxydivorans Nor1
Length = 556
Score = 73.7 bits (173), Expect = 3e-12
Identities = 40/113 (35%), Positives = 61/113 (53%)
Frame = +2
Query: 215 MGIDGNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATG 394
M + G+ I+ ESL +QGV+ VFG G ++ A A +++I +EQAA +AA
Sbjct: 1 MKLSGSRIIVESLLRQGVDTVFGYPGGAIMPLYDALYDAPIRHILTVHEQAAAHAADGYA 60
Query: 395 YLTGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQE 553
+G+ GVC+ SGPG + + G+A A ++ P+V I G FQE
Sbjct: 61 RSSGRVGVCIATSGPGATNLVTGLATAYMDSSPVVAITGQVATKLIGRDAFQE 113
>UniRef50_P40811 Cluster: Acetolactate synthase isozyme 3 large
subunit; n=249; Bacteria|Rep: Acetolactate synthase
isozyme 3 large subunit - Salmonella typhimurium
Length = 574
Score = 73.7 bits (173), Expect = 3e-12
Identities = 44/126 (34%), Positives = 66/126 (52%), Gaps = 1/126 (0%)
Frame = +2
Query: 221 IDGNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAG-LKYIGMRNEQAACYAAQATGY 397
+ G ++ SL QGV+ VFG G V++ A + G + ++ +R+EQAA + A
Sbjct: 4 LSGAEMVVRSLIDQGVKQVFGYPGGAVLDIYDALHTVGGIDHVLVRHEQAAVHMADGLAR 63
Query: 398 LTGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQVDSSR 577
TG GV LV SGPG + I G+A A ++ PLV+++G FQE V SR
Sbjct: 64 ATGDVGVVLVTSGPGATNAITGIATAYMDSIPLVILSGQVATSLIGYDAFQECDMVGISR 123
Query: 578 MYCKYA 595
K++
Sbjct: 124 PVVKHS 129
>UniRef50_A4F7C5 Cluster: Acetolactate synthase large subunit; n=1;
Saccharopolyspora erythraea NRRL 2338|Rep: Acetolactate
synthase large subunit - Saccharopolyspora erythraea
(strain NRRL 23338)
Length = 560
Score = 73.3 bits (172), Expect = 4e-12
Identities = 40/125 (32%), Positives = 65/125 (52%)
Frame = +2
Query: 239 LAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTGKPGV 418
+ + L++ GV +FG+ G +E A + AG++ + R+++ A A +G+PGV
Sbjct: 13 VVDHLREAGVSVLFGLPGDD-LEALCALEKAGMRMVLCRDQRNAVCMAAGYAIQSGRPGV 71
Query: 419 CLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQVDSSRMYCKYAA 598
C+V GP + + +GG+ A+ P+VV+AG D G FQE QV K+A
Sbjct: 72 CVVGKGPAVANAVGGLLEARSAGAPVVVLAGGTGTDRRGSGAFQELDQVPLVTPVVKWAH 131
Query: 599 RPPSP 613
R P
Sbjct: 132 RIDHP 136
>UniRef50_Q0PAU3 Cluster: Acetolactate synthase large subunit; n=16;
Proteobacteria|Rep: Acetolactate synthase large subunit
- Campylobacter jejuni
Length = 566
Score = 72.9 bits (171), Expect = 6e-12
Identities = 43/125 (34%), Positives = 67/125 (53%), Gaps = 1/125 (0%)
Frame = +2
Query: 221 IDGNTILAESLKKQGVEYVFGIVGIPVIETA-MAFQSAGLKYIGMRNEQAACYAAQATGY 397
+ G+ ++ E+LK++ V+ VFG G + + K+I +R+EQAA +AA A
Sbjct: 4 LSGSAMICEALKEENVKIVFGYPGGAALNIYDEIYNQKYFKHILVRHEQAALHAADAYAR 63
Query: 398 LTGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQVDSSR 577
++G+ GV +V SGPG + I G+A A + PLV+I+G FQE V SR
Sbjct: 64 MSGEVGVAIVTSGPGFTNTITGLATAYSDSIPLVLISGQVANSLIGTDAFQEIDAVGISR 123
Query: 578 MYCKY 592
K+
Sbjct: 124 PCVKH 128
>UniRef50_A5GC69 Cluster: Acetolactate synthase; n=3; cellular
organisms|Rep: Acetolactate synthase - Geobacter
uraniumreducens Rf4
Length = 560
Score = 72.9 bits (171), Expect = 6e-12
Identities = 42/123 (34%), Positives = 62/123 (50%), Gaps = 1/123 (0%)
Frame = +2
Query: 227 GNTILAESLKKQGVEYVFGIVGIPVIETAMA-FQSAGLKYIGMRNEQAACYAAQATGYLT 403
G IL E LK++GV+ +FG G + A + L++I +R+EQ A +AA T
Sbjct: 4 GAQILLECLKREGVDTIFGYPGAKTLLVHDALYDDPDLRHILVRHEQGAAHAADGYARTT 63
Query: 404 GKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQVDSSRMY 583
GK GVCL SGPG + + G+A A ++ PLV + FQE + +R
Sbjct: 64 GKVGVCLTTSGPGATNLVTGIATAHMDSIPLVALTCQVATTDIGSDAFQEADMIGITRPI 123
Query: 584 CKY 592
K+
Sbjct: 124 TKH 126
>UniRef50_Q7W2M5 Cluster: Acetolactate synthase large subunit; n=53;
Proteobacteria|Rep: Acetolactate synthase large subunit
- Bordetella parapertussis
Length = 616
Score = 72.5 bits (170), Expect = 7e-12
Identities = 42/133 (31%), Positives = 70/133 (52%), Gaps = 1/133 (0%)
Frame = +2
Query: 197 QKLNGSMGIDGNTILAESLKKQGVEYVFGIVGIPVIETAMA-FQSAGLKYIGMRNEQAAC 373
Q+ + ++G IL +L ++GV+ VFG G V+ A + L+++ +R+EQAA
Sbjct: 17 QQAEHAAAVNGAKILLHTLIERGVDTVFGYPGGAVLPLYDALYAEPRLRHVLVRHEQAAV 76
Query: 374 YAAQATGYLTGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQE 553
+AA+ TG+PGV V SGPG+ + G+ +A + P++ I+G FQE
Sbjct: 77 HAAEGYARTTGRPGVVFVTSGPGMANTTSGLLDAMCDSVPVLCISGQVSTAAIGTDAFQE 136
Query: 554 WPQVDSSRMYCKY 592
+ SR K+
Sbjct: 137 CDAIGISRSVTKW 149
>UniRef50_Q39P46 Cluster: Acetolactate synthase, large subunit;
n=15; Proteobacteria|Rep: Acetolactate synthase, large
subunit - Burkholderia sp. (strain 383) (Burkholderia
cepacia (strain ATCC 17760/ NCIB 9086 / R18194))
Length = 564
Score = 72.5 bits (170), Expect = 7e-12
Identities = 31/90 (34%), Positives = 55/90 (61%)
Frame = +2
Query: 239 LAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTGKPGV 418
L + L++ GVE VFGI G+ +E ++ ++++ R+EQ A + A +TG+PGV
Sbjct: 32 LVDLLERHGVECVFGIPGVHTVELYRGLAASSIRHVTPRHEQGAGFMADGYARVTGRPGV 91
Query: 419 CLVVSGPGLLHCIGGMANAQVNCWPLVVIA 508
C +++GPG+ + MA A + P++VI+
Sbjct: 92 CFIITGPGMTNIATAMAQAYADSIPMLVIS 121
>UniRef50_O27639 Cluster: Acetolactate synthase, large subunit
homolog; n=1; Methanothermobacter thermautotrophicus
str. Delta H|Rep: Acetolactate synthase, large subunit
homolog - Methanobacterium thermoautotrophicum
Length = 524
Score = 72.5 bits (170), Expect = 7e-12
Identities = 37/106 (34%), Positives = 59/106 (55%)
Frame = +2
Query: 236 ILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTGKPG 415
+LA L++ G ++FG G ++ A + +GL+++ MR+EQ A +AA +G PG
Sbjct: 7 VLAGILEEAGFTHIFGHPGEQILPLYEALRKSGLEHVLMRHEQGAVHAADGYARASGGPG 66
Query: 416 VCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQE 553
VC+ GPG L+ + G+A A + PL+ + G P G FQE
Sbjct: 67 VCVATGGPGALNLVMGVAAASTDSVPLIAMTGDLPRG-GGPGRFQE 111
>UniRef50_Q6DDK5 Cluster: Ilvbl-prov protein; n=2; Bilateria|Rep:
Ilvbl-prov protein - Xenopus laevis (African clawed
frog)
Length = 649
Score = 71.7 bits (168), Expect = 1e-11
Identities = 38/125 (30%), Positives = 67/125 (53%)
Frame = +2
Query: 227 GNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTG 406
G ++A+ LK V ++F + G + +A + ++ I +R+E +A +AA A L+G
Sbjct: 40 GGELVADVLKAHDVRFLFTLCGGHISPILVAAERQNIRVIDVRHEASAVFAADAVSRLSG 99
Query: 407 KPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQVDSSRMYC 586
GV V +GPGL + + + NAQ+ P+V++AG+ G Q+ Q+ R C
Sbjct: 100 TVGVAAVTAGPGLTNTVTAVKNAQMAESPIVLLAGAAAGLLRGRGSLQDIDQLSLFRPLC 159
Query: 587 KYAAR 601
K++ R
Sbjct: 160 KWSGR 164
>UniRef50_Q8G7H0 Cluster: Acetolactate synthase; n=2;
Bifidobacterium longum|Rep: Acetolactate synthase -
Bifidobacterium longum
Length = 655
Score = 71.7 bits (168), Expect = 1e-11
Identities = 41/110 (37%), Positives = 60/110 (54%), Gaps = 1/110 (0%)
Frame = +2
Query: 227 GNTILAESLKKQGVEYVFGIVGIPVIETAMAFQ-SAGLKYIGMRNEQAACYAAQATGYLT 403
G L SL+ GVE VFGI G ++ + + +++ MR+EQAA +AA+ T
Sbjct: 33 GAQALIRSLEDLGVEDVFGIPGGAILPVYHEIKDNTKFRFVLMRHEQAAGHAAEGYALAT 92
Query: 404 GKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQE 553
GK GVC+V SGPG + + +A+A ++ P+VVI G FQE
Sbjct: 93 GKVGVCIVTSGPGATNVVTAIADANMDSVPMVVITGQVGVQAIGTDAFQE 142
>UniRef50_P96591 Cluster: YdaP protein; n=11; Bacillaceae|Rep: YdaP
protein - Bacillus subtilis
Length = 574
Score = 71.7 bits (168), Expect = 1e-11
Identities = 39/107 (36%), Positives = 61/107 (57%), Gaps = 2/107 (1%)
Frame = +2
Query: 239 LAESLKKQGVEYVFGIVGIPVIE--TAMAFQSAGLKYIGMRNEQAACYAAQATGYLTGKP 412
+ E L++ GV++V+GI G + E + + LK+I R+E+ A AA A LTGK
Sbjct: 10 MTELLEQWGVDHVYGIPGDSINEFIEELRHERNQLKFIQTRHEEVAALAAAAEAKLTGKI 69
Query: 413 GVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQE 553
GVCL ++GPG +H + G+ +A+ + P++ IAG FQE
Sbjct: 70 GVCLSIAGPGAVHLLNGLYDAKADGAPVLAIAGQVSSGEVGRDYFQE 116
>UniRef50_Q28MM5 Cluster: Thiamine pyrophosphate enzyme-like TPP
binding protein; n=4; Bacteria|Rep: Thiamine
pyrophosphate enzyme-like TPP binding protein -
Jannaschia sp. (strain CCS1)
Length = 656
Score = 71.7 bits (168), Expect = 1e-11
Identities = 37/109 (33%), Positives = 63/109 (57%), Gaps = 4/109 (3%)
Frame = +2
Query: 239 LAESLKKQGVEYVFGIVGIPVIETAMAFQ----SAGLKYIGMRNEQAACYAAQATGYLTG 406
+AE++ G++ VFG+VG + + A + ++Y G+R+E AA +AA A G LTG
Sbjct: 123 MAETMVNWGIQSVFGMVGHSNLGLSDAIRRRVADGEMRYYGIRHEGAAAFAASAYGKLTG 182
Query: 407 KPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQE 553
+P CL ++GPG + + GM +A+V+ P++ + G G FQ+
Sbjct: 183 RPAACLTIAGPGATNLLTGMWDAKVDRAPVLALTGQVQTQVFGPGAFQD 231
>UniRef50_Q97EE4 Cluster: Acetolactate synthase; n=10;
Clostridiales|Rep: Acetolactate synthase - Clostridium
acetobutylicum
Length = 554
Score = 70.9 bits (166), Expect = 2e-11
Identities = 41/114 (35%), Positives = 60/114 (52%), Gaps = 1/114 (0%)
Frame = +2
Query: 215 MGIDGNTILAESLKKQGVEYVFGIVGIPVIETAMAFQS-AGLKYIGMRNEQAACYAAQAT 391
M +G+ I+ E LK+QGV+ +FG G V+ A S + ++ + +EQ A +AA
Sbjct: 1 MKYNGSRIILECLKEQGVDTIFGYPGGAVLNIFDALYSFSEIRCVLTSHEQGASHAADGY 60
Query: 392 GYLTGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQE 553
TGK GVCL SGPG + + G+A A ++ P+V I G FQE
Sbjct: 61 ARATGKVGVCLATSGPGATNLVTGIATAYMDSVPMVAITGQVATSLIGKDSFQE 114
>UniRef50_Q0SHU3 Cluster: Pyruvate dehydrogenase; n=15;
Bacteria|Rep: Pyruvate dehydrogenase - Rhodococcus sp.
(strain RHA1)
Length = 591
Score = 70.9 bits (166), Expect = 2e-11
Identities = 41/111 (36%), Positives = 61/111 (54%), Gaps = 6/111 (5%)
Frame = +2
Query: 239 LAESLKKQGVEYVFGIVGI---PVIETAMAFQSA---GLKYIGMRNEQAACYAAQATGYL 400
L L+ GV+ ++GIVG PV++ A G+ +I +R+E+AA +AA A +
Sbjct: 10 LVRQLQDAGVQRIYGIVGDSLNPVVDAVRRSGGAAKGGIDWIHVRHEEAAAFAAAAEAQV 69
Query: 401 TGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQE 553
TGK VC GPG LH I G+ +A + P++ IA P + +G FQE
Sbjct: 70 TGKLAVCAGSCGPGNLHLINGLYDADRSGAPVLAIAAQIPSEQIGLGFFQE 120
>UniRef50_O28494 Cluster: Acetolactate synthase, large subunit; n=3;
Archaea|Rep: Acetolactate synthase, large subunit -
Archaeoglobus fulgidus
Length = 545
Score = 70.9 bits (166), Expect = 2e-11
Identities = 41/99 (41%), Positives = 57/99 (57%), Gaps = 2/99 (2%)
Frame = +2
Query: 221 IDGNTILAESLKKQGVEYVFGIVGIPVIETAMAFQS--AGLKYIGMRNEQAACYAAQATG 394
+D +AE LK GV V+GI+G +++ A ++YI R+EQ A A A G
Sbjct: 1 MDAAHAVAECLKNFGVGRVYGIIGTSIVDFVDALYDYREEIRYISCRHEQVAASMADAEG 60
Query: 395 YLTGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAG 511
LTG PGV LV + PG L+ G+ANA + P+VVI+G
Sbjct: 61 RLTGFPGVSLVHAAPGTLNAAIGVANAYKDGSPMVVISG 99
>UniRef50_Q82PG6 Cluster: Putative pyruvate dehydrogenase/oxidase
FAD and thiamine PPi cofactors; n=1; Streptomyces
avermitilis|Rep: Putative pyruvate dehydrogenase/oxidase
FAD and thiamine PPi cofactors - Streptomyces
avermitilis
Length = 587
Score = 70.5 bits (165), Expect = 3e-11
Identities = 39/121 (32%), Positives = 67/121 (55%), Gaps = 1/121 (0%)
Frame = +2
Query: 236 ILAESLKKQGVEYVFGIVGIPVIETAMAFQSA-GLKYIGMRNEQAACYAAQATGYLTGKP 412
++ ++L + GV VFG+VG + A ++ ++++G R+E+AA +AA A L+G
Sbjct: 8 VIVDALSELGVRQVFGVVGDALNPVTDAIRTTEDVEWVGCRHEEAAAFAASAQSQLSGTL 67
Query: 413 GVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQVDSSRMYCKY 592
GVC+ GPG +H + G+ +A + P++ IAG P FQE VD+ ++
Sbjct: 68 GVCMGTVGPGSVHLLNGLYDAAKSRTPVLAIAGQVPLAELGSDYFQE---VDNDALFSDV 124
Query: 593 A 595
A
Sbjct: 125 A 125
>UniRef50_A7R4D4 Cluster: Chromosome undetermined scaffold_656,
whole genome shotgun sequence; n=2; Vitis vinifera|Rep:
Chromosome undetermined scaffold_656, whole genome
shotgun sequence - Vitis vinifera (Grape)
Length = 96
Score = 70.5 bits (165), Expect = 3e-11
Identities = 36/96 (37%), Positives = 58/96 (60%), Gaps = 1/96 (1%)
Frame = +2
Query: 227 GNTILAESLKKQGVEYVFGIVGIPVIETAMAF-QSAGLKYIGMRNEQAACYAAQATGYLT 403
G+ IL E+L+++GV +VFG G +E A +S+ ++ + R+EQ +AA +
Sbjct: 1 GSDILVEALEREGVTHVFGYPGGASMEIHEALARSSMIRNVLPRHEQGGIFAADGYARAS 60
Query: 404 GKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAG 511
G+PGVCL SGPG + I G+A+A + P+V + G
Sbjct: 61 GRPGVCLTSSGPGATNIISGIADANFDSIPIVAVTG 96
>UniRef50_P66947 Cluster: Probable acetolactate synthase; n=12;
Mycobacterium|Rep: Probable acetolactate synthase -
Mycobacterium bovis
Length = 547
Score = 70.5 bits (165), Expect = 3e-11
Identities = 40/125 (32%), Positives = 62/125 (49%)
Frame = +2
Query: 236 ILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTGKPG 415
++A LK G++ VF + G + + G++ I R+EQ A +AA+ +T PG
Sbjct: 16 LIARRLKASGIDTVFTLSGGHLFSIYDGCREEGIRLIDTRHEQTAAFAAEGWSKVTRVPG 75
Query: 416 VCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQVDSSRMYCKYA 595
V + +GPG+ + + MA AQ N PLVV+ G P +G QE V ++A
Sbjct: 76 VAALTAGPGITNGMSAMAAAQQNQSPLVVLGGRAPALRWGMGSLQEIDHVPFVAPVARFA 135
Query: 596 ARPPS 610
A S
Sbjct: 136 ATAQS 140
>UniRef50_Q89R07 Cluster: Bll2965 protein; n=4; Bacteria|Rep:
Bll2965 protein - Bradyrhizobium japonicum
Length = 541
Score = 70.1 bits (164), Expect = 4e-11
Identities = 45/134 (33%), Positives = 64/134 (47%), Gaps = 3/134 (2%)
Frame = +2
Query: 221 IDGNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYL 400
+ G + L GV+ VFG+ G + AF A LK IG R+EQA Y A
Sbjct: 4 LTGGEAIVSGLVAHGVDTVFGLPGAQIYGLFDAFHQAQLKVIGARHEQACGYMAFGYARS 63
Query: 401 TGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDH--EAIGGFQEWP-QVDS 571
+G+PGV VV GPG+L+ + A P++ + G P + G E P Q+ +
Sbjct: 64 SGRPGVFSVVPGPGVLNASAALLTAYGCNEPVLCVTGQVPTQFLGKGRGHLHEMPDQLAT 123
Query: 572 SRMYCKYAARPPSP 613
R Y K+A R +P
Sbjct: 124 LRTYVKWADRIEAP 137
>UniRef50_Q04D18 Cluster: Thiamine pyrophosphate-requiring enzyme
(Acetolactate synthase, pyruvate dehydrogenase
(Cytochrome), glyoxylate carboligase, phosphonopyruvate
decarboxylase); n=3; Lactobacillales|Rep: Thiamine
pyrophosphate-requiring enzyme (Acetolactate synthase,
pyruvate dehydrogenase (Cytochrome), glyoxylate
carboligase, phosphonopyruvate decarboxylase) -
Oenococcus oeni (strain BAA-331 / PSU-1)
Length = 578
Score = 70.1 bits (164), Expect = 4e-11
Identities = 38/111 (34%), Positives = 62/111 (55%), Gaps = 2/111 (1%)
Frame = +2
Query: 227 GNTILAESLKKQGVEYVFGIVGIPVIET--AMAFQSAGLKYIGMRNEQAACYAAQATGYL 400
G+ +L L G++ V+G+ G V T A+ Q +K+I +R+E+ A AA A+
Sbjct: 6 GSDLLVSVLTDWGIKEVYGLPGDSVDTTVDALRRQKDKIKFIQVRHEEVASLAASASAKY 65
Query: 401 TGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQE 553
TGK GVCL + GPG +H + G+ +A+++ P++ + G G FQE
Sbjct: 66 TGKIGVCLSIGGPGAIHLLNGLYDAKMDHVPVLALLGQVTSQSLNEGYFQE 116
>UniRef50_A6DLM5 Cluster: Acetolactate synthase; n=1; Lentisphaera
araneosa HTCC2155|Rep: Acetolactate synthase -
Lentisphaera araneosa HTCC2155
Length = 569
Score = 70.1 bits (164), Expect = 4e-11
Identities = 41/104 (39%), Positives = 56/104 (53%), Gaps = 3/104 (2%)
Frame = +2
Query: 251 LKKQGVEYVFGIVG---IPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTGKPGVC 421
L+K GVEY+FG G IP + A+ ++ I +R+EQ A + A TGKPGV
Sbjct: 11 LEKHGVEYIFGYSGGAAIPFFD-ALVTTKTEIELILVRHEQGATHMADGYARATGKPGVV 69
Query: 422 LVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQE 553
LV SGPG + I G+ AQ++ P++VI G FQE
Sbjct: 70 LVTSGPGATNTITGLITAQMDSVPMIVITGQTISPMLGKDAFQE 113
>UniRef50_A1WES2 Cluster: Thiamine pyrophosphate enzyme TPP binding
domain protein; n=6; Proteobacteria|Rep: Thiamine
pyrophosphate enzyme TPP binding domain protein -
Verminephrobacter eiseniae (strain EF01-2)
Length = 576
Score = 70.1 bits (164), Expect = 4e-11
Identities = 34/109 (31%), Positives = 58/109 (53%)
Frame = +2
Query: 215 MGIDGNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATG 394
M I +L L+ GVE+VFGI GI +E ++ +++I R+EQ A + A
Sbjct: 1 MTITLGQVLIRILEDYGVEHVFGIPGIHTVELYRGLAASSIRHITPRHEQGAGFMADGYA 60
Query: 395 YLTGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIG 541
+GKPGVC +++GPG+ + + A + P++V++ +H G
Sbjct: 61 RASGKPGVCFIITGPGMTNVATALGQAYSDSVPMLVLSSVHARNHLGAG 109
>UniRef50_Q01Q83 Cluster: Thiamine pyrophosphate enzyme domain
protein TPP-binding; n=1; Solibacter usitatus
Ellin6076|Rep: Thiamine pyrophosphate enzyme domain
protein TPP-binding - Solibacter usitatus (strain
Ellin6076)
Length = 548
Score = 69.7 bits (163), Expect = 5e-11
Identities = 40/128 (31%), Positives = 64/128 (50%)
Frame = +2
Query: 224 DGNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLT 403
+G + +S G++ VF +VG + E A AG+ + MR+E +AA A +
Sbjct: 3 NGAELFVQSAAHLGIDTVFTLVGDHLNEVLAAAARAGMHIVDMRHESGVTHAADAWARIH 62
Query: 404 GKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQVDSSRMY 583
+P + LV GPG + + G+A A + PL+ ++GS P FQ+ QV +R
Sbjct: 63 RRPALSLVTGGPGHTNSLTGIATANLAGSPLIAVSGSRPRALADRQAFQDIDQVGMARPA 122
Query: 584 CKYAARPP 607
K+AA P
Sbjct: 123 VKWAAEVP 130
>UniRef50_A0PNI1 Cluster: Acetolactate synthase (Large subunit)
IlvB1_2; n=1; Mycobacterium ulcerans Agy99|Rep:
Acetolactate synthase (Large subunit) IlvB1_2 -
Mycobacterium ulcerans (strain Agy99)
Length = 558
Score = 69.7 bits (163), Expect = 5e-11
Identities = 45/121 (37%), Positives = 65/121 (53%), Gaps = 1/121 (0%)
Frame = +2
Query: 251 LKKQGVEYVFGIVGIPVIETAMAFQSAG-LKYIGMRNEQAACYAAQATGYLTGKPGVCLV 427
L +GVEYVFGI G + A ++ G +K+I R+ QAA +AA A G LTGK V +
Sbjct: 14 LAAEGVEYVFGIPGDENLHFMEALRNDGRIKFILFRHLQAAGFAAAAYGRLTGKLAVAMS 73
Query: 428 VSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQVDSSRMYCKYAARPP 607
G G ++ +A+A + P++VI G +G +Q VD R K+AA+ P
Sbjct: 74 TLGAGAMNLTTLVAHAYLTAMPMLVITGQKAVRDNRMGQYQIVDVVDVMRPITKFAAKIP 133
Query: 608 S 610
S
Sbjct: 134 S 134
>UniRef50_Q8TPF5 Cluster: Acetolactate synthase; n=12; cellular
organisms|Rep: Acetolactate synthase - Methanosarcina
acetivorans
Length = 583
Score = 69.7 bits (163), Expect = 5e-11
Identities = 33/91 (36%), Positives = 55/91 (60%)
Frame = +2
Query: 236 ILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTGKPG 415
++ + L+ +GVEY+FG+ G I A + +++I +R+EQ A + A G +TGK G
Sbjct: 42 LMVQCLENEGVEYIFGLPGEENIRFVDALGDSTIRFIVVRHEQGASFMADIYGRVTGKAG 101
Query: 416 VCLVVSGPGLLHCIGGMANAQVNCWPLVVIA 508
VC+ GPG ++ + G A+A + PLV I+
Sbjct: 102 VCISTLGPGAINLLLGTADAFTDSTPLVAIS 132
>UniRef50_P00892 Cluster: Acetolactate synthase isozyme 2 large
subunit; n=134; Proteobacteria|Rep: Acetolactate
synthase isozyme 2 large subunit - Escherichia coli
(strain K12)
Length = 548
Score = 69.7 bits (163), Expect = 5e-11
Identities = 38/111 (34%), Positives = 57/111 (51%)
Frame = +2
Query: 221 IDGNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYL 400
++G + +L+ QGV VFG G ++ A G++++ R+EQ A AA
Sbjct: 1 MNGAQWVVHALRAQGVNTVFGYPGGAIMPVYDALYDGGVEHLLCRHEQGAAMAAIGYARA 60
Query: 401 TGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQE 553
TGK GVC+ SGPG + I G+A+A ++ P+V I G FQE
Sbjct: 61 TGKTGVCIATSGPGATNLITGLADALLDSIPVVAITGQVSAPFIGTDAFQE 111
>UniRef50_Q04524 Cluster: Acetolactate synthase, catabolic; n=25;
Gammaproteobacteria|Rep: Acetolactate synthase,
catabolic - Klebsiella terrigena (Raoultella terrigena)
Length = 559
Score = 69.7 bits (163), Expect = 5e-11
Identities = 42/123 (34%), Positives = 60/123 (48%)
Frame = +2
Query: 227 GNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTG 406
G ++ L+ QGV VFGI G + + + + ++ I +R+E A + A A G +TG
Sbjct: 13 GADLIVSQLEAQGVRQVFGIPGAKIDKVFDSLLDSSIRIIPVRHEANAAFMAAAVGRITG 72
Query: 407 KPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQVDSSRMYC 586
K GV LV SGPG + I GMA A P+V + G+ +A Q V
Sbjct: 73 KAGVALVTSGPGCSNLITGMATANSEGDPVVALGGAVKRADKAKLVHQSMDTVAMFSPVT 132
Query: 587 KYA 595
KYA
Sbjct: 133 KYA 135
>UniRef50_Q186C0 Cluster: Acetolactate synthase; n=2; Clostridium
difficile|Rep: Acetolactate synthase - Clostridium
difficile (strain 630)
Length = 564
Score = 69.3 bits (162), Expect = 7e-11
Identities = 41/115 (35%), Positives = 59/115 (51%), Gaps = 2/115 (1%)
Frame = +2
Query: 215 MGIDGNTILAESLKKQGVEYVFGIVGIPVIET--AMAFQSAGLKYIGMRNEQAACYAAQA 388
M ++G ++ E LKK+G++ +FG G VI A+ S K+I +EQ +AA
Sbjct: 1 MRMNGAKVILECLKKEGIDTIFGYPGGAVIPLYDALYDYSDDFKHIRTSHEQGLVHAADG 60
Query: 389 TGYLTGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQE 553
T GVC SGPG + I G+A A ++ P+VVI+G P FQE
Sbjct: 61 YARSTNTVGVCFTTSGPGATNAITGIATAFMDSSPMVVISGQVPTSLLGKDSFQE 115
>UniRef50_Q54YW0 Cluster: Putative uncharacterized protein; n=3;
Eukaryota|Rep: Putative uncharacterized protein -
Dictyostelium discoideum AX4
Length = 904
Score = 69.3 bits (162), Expect = 7e-11
Identities = 38/124 (30%), Positives = 65/124 (52%)
Frame = +2
Query: 227 GNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTG 406
G ++A L KQGV+++F + G + + G++ I +R+E +AA LTG
Sbjct: 311 GGELVANVLSKQGVKFLFTLTGGHIAPILVESDKIGIRVIDVRHESTTVFAADGVFRLTG 370
Query: 407 KPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQVDSSRMYC 586
PGV +V +GPGL + I + NAQ+ +V+I G+ + + G Q+ Q R +
Sbjct: 371 IPGVAVVTAGPGLTNTITAVKNAQMAQSGVVLIGGATSDLLKGKGSLQDIDQFALLRPHV 430
Query: 587 KYAA 598
K+ +
Sbjct: 431 KWCS 434
>UniRef50_Q93PS3 Cluster: Sulfoacetaldehyde acetyltransferase; n=5;
Peptococcaceae|Rep: Sulfoacetaldehyde acetyltransferase
- Desulfonispora thiosulfatigenes
Length = 584
Score = 68.9 bits (161), Expect = 9e-11
Identities = 40/125 (32%), Positives = 64/125 (51%)
Frame = +2
Query: 239 LAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTGKPGV 418
+ E L +GV +V GI+G ++ + +AG+++I +R+EQ A + A +TGK V
Sbjct: 12 MTEVLVNEGVTHVTGILGSAFMDMLDLWPTAGIEFIAVRHEQTAGHMQDAYCRITGKASV 71
Query: 419 CLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQVDSSRMYCKYAA 598
C+ +GPG+ + + +A A P+VV+ S GFQE QV R K
Sbjct: 72 CIGQNGPGVTNLVTCVAAANQAHTPMVVLGPSAGTPTVGWDGFQECDQVSIFRSITKQVL 131
Query: 599 RPPSP 613
+ P P
Sbjct: 132 QVPHP 136
>UniRef50_P07342 Cluster: Acetolactate synthase catalytic subunit,
mitochondrial precursor; n=41; Dikarya|Rep: Acetolactate
synthase catalytic subunit, mitochondrial precursor -
Saccharomyces cerevisiae (Baker's yeast)
Length = 687
Score = 68.9 bits (161), Expect = 9e-11
Identities = 41/127 (32%), Positives = 63/127 (49%), Gaps = 1/127 (0%)
Frame = +2
Query: 215 MGIDGNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAG-LKYIGMRNEQAACYAAQAT 391
+G+ G I E + +Q V+ VFG G ++ A ++ ++ ++EQ A + A+
Sbjct: 90 VGLTGGQIFNEMMSRQNVDTVFGYPGGAILPVYDAIHNSDKFNFVLPKHEQGAGHMAEGY 149
Query: 392 GYLTGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQVDS 571
+GKPGV LV SGPG + + MA+A + P+VV G P FQE V
Sbjct: 150 ARASGKPGVVLVTSGPGATNVVTPMADAFADGIPMVVFTGQVPTSAIGTDAFQEADVVGI 209
Query: 572 SRMYCKY 592
SR K+
Sbjct: 210 SRSCTKW 216
>UniRef50_P08142 Cluster: Acetolactate synthase isozyme 1 large
subunit; n=49; Bacteria|Rep: Acetolactate synthase
isozyme 1 large subunit - Escherichia coli (strain K12)
Length = 562
Score = 68.9 bits (161), Expect = 9e-11
Identities = 37/110 (33%), Positives = 58/110 (52%), Gaps = 1/110 (0%)
Frame = +2
Query: 227 GNTILAESLKKQGVEYVFGIVGIPVIETAMAF-QSAGLKYIGMRNEQAACYAAQATGYLT 403
G + L++QG++ V GI G ++ A QS +++I R+EQ A + AQ
Sbjct: 15 GAEFIVHFLEQQGIKIVTGIPGGSILPVYDALSQSTQIRHILARHEQGAGFIAQGMARTD 74
Query: 404 GKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQE 553
GKP VC+ SGPG + + +A+A+++ PL+ I G P FQE
Sbjct: 75 GKPAVCMACSGPGATNLVTAIADARLDSIPLICITGQVPASMIGTDAFQE 124
>UniRef50_Q4KD62 Cluster: Acetolactate synthase, large subunit,
putative; n=11; Pseudomonas|Rep: Acetolactate synthase,
large subunit, putative - Pseudomonas fluorescens
(strain Pf-5 / ATCC BAA-477)
Length = 535
Score = 68.5 bits (160), Expect = 1e-10
Identities = 33/96 (34%), Positives = 53/96 (55%)
Frame = +2
Query: 221 IDGNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYL 400
+ G L L GV+ VFGI G+ +E +G++++ R+EQ A + A +
Sbjct: 6 LTGGQALVRLLAGYGVDTVFGIPGVHTLELYRGLPGSGIRHVLTRHEQGAGFMADGYARV 65
Query: 401 TGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIA 508
+GKPGVC V+SGPG+ + + A + PL+VI+
Sbjct: 66 SGKPGVCFVISGPGVTNVATPIGQAYADSIPLLVIS 101
>UniRef50_Q8F341 Cluster: Acetolactate synthase large subunit; n=5;
Bacteria|Rep: Acetolactate synthase large subunit -
Leptospira interrogans
Length = 592
Score = 68.1 bits (159), Expect = 2e-10
Identities = 36/115 (31%), Positives = 63/115 (54%), Gaps = 1/115 (0%)
Frame = +2
Query: 212 SMGIDGNTILAESLKKQGVEYVFGIVGIPVIETA-MAFQSAGLKYIGMRNEQAACYAAQA 388
S + G ++ E L++ GV+ VFG G ++ ++S +K+I +R+EQ A + A+
Sbjct: 28 SRRVTGARLMVELLEEYGVDVVFGYPGGAILPFYDEIYKSKKIKHILVRHEQGAVHMAEG 87
Query: 389 TGYLTGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQE 553
TGK GVC+ SGPG + + G+ +A+++ P++ I G + FQE
Sbjct: 88 YARATGKLGVCIATSGPGATNLVTGITDAKMDSVPILAITGQVATNAIGTDAFQE 142
>UniRef50_Q5LLG2 Cluster: Thiamine pyrophosphate-dependent enzyme;
n=10; Alphaproteobacteria|Rep: Thiamine
pyrophosphate-dependent enzyme - Silicibacter pomeroyi
Length = 533
Score = 68.1 bits (159), Expect = 2e-10
Identities = 30/91 (32%), Positives = 54/91 (59%)
Frame = +2
Query: 239 LAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTGKPGV 418
L L +GV VFGI G+ IE ++G++++ R+EQ A + A ++G+PGV
Sbjct: 8 LVAGLAARGVTCVFGIPGVHTIEMYRGLAASGIRHVTPRHEQGAGFMADGYARVSGRPGV 67
Query: 419 CLVVSGPGLLHCIGGMANAQVNCWPLVVIAG 511
V++GPG+ + + M A+ + P++V++G
Sbjct: 68 AFVITGPGVTNTLTAMGQARADSVPMLVVSG 98
>UniRef50_Q96F08 Cluster: IlvB (Bacterial acetolactate
synthase)-like; n=36; cellular organisms|Rep: IlvB
(Bacterial acetolactate synthase)-like - Homo sapiens
(Human)
Length = 632
Score = 68.1 bits (159), Expect = 2e-10
Identities = 36/122 (29%), Positives = 63/122 (51%)
Frame = +2
Query: 227 GNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTG 406
G +A L+ GV ++F +VG + +A + G++ + R+E A +AA A L+G
Sbjct: 54 GGENVAAVLRAHGVRFIFTLVGGHISPLLVACEKLGIRVVDTRHEVTAVFAADAMARLSG 113
Query: 407 KPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQVDSSRMYC 586
GV V +GPGL + + + NAQ+ P++++ G+ + G Q Q+ R C
Sbjct: 114 TVGVAAVTAGPGLTNTVTAVKNAQMAQSPILLLGGAASTLLQNRGALQAVDQLSLFRPLC 173
Query: 587 KY 592
K+
Sbjct: 174 KF 175
>UniRef50_Q59GP4 Cluster: IlvB (Bacterial acetolactate
synthase)-like isoform 1 variant; n=1; Homo sapiens|Rep:
IlvB (Bacterial acetolactate synthase)-like isoform 1
variant - Homo sapiens (Human)
Length = 427
Score = 68.1 bits (159), Expect = 2e-10
Identities = 36/122 (29%), Positives = 63/122 (51%)
Frame = +2
Query: 227 GNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTG 406
G +A L+ GV ++F +VG + +A + G++ + R+E A +AA A L+G
Sbjct: 19 GGENVAAVLRAHGVRFIFTLVGGHISPLLVACEKLGIRVVDTRHEVTAVFAADAMARLSG 78
Query: 407 KPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQVDSSRMYC 586
GV V +GPGL + + + NAQ+ P++++ G+ + G Q Q+ R C
Sbjct: 79 TVGVAAVTAGPGLTNTVTAVKNAQMAQSPILLLGGAASTLLQNRGALQAVDQLSLFRPLC 138
Query: 587 KY 592
K+
Sbjct: 139 KF 140
>UniRef50_Q64QU8 Cluster: Pyruvate dehydrogenase; n=6;
Bacteroidetes|Rep: Pyruvate dehydrogenase - Bacteroides
fragilis
Length = 579
Score = 67.7 bits (158), Expect = 2e-10
Identities = 43/133 (32%), Positives = 67/133 (50%), Gaps = 5/133 (3%)
Frame = +2
Query: 239 LAESLKKQGVEYVFGIVGIPVIETAMAF-QSAGLKYIGMRNEQAACYAAQATGYLTGKPG 415
L ++L + GV ++ + G + E A Q+ +K+I +R+E+ YAA A LTG PG
Sbjct: 9 LVDTLIEAGVRRIYAVTGDSLNEVNEAVRQNEAMKWIHVRHEETGAYAAGAEAQLTGLPG 68
Query: 416 VCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQV---DSSRMYC 586
C SGPG +H I G+ +A + P++ IA + P FQE V + Y
Sbjct: 69 CCAGSSGPGHVHLINGLYDAHRSGAPVIAIASTIPTGEFGTEYFQETNTVKLFNDCSFYN 128
Query: 587 KYAARPPS-PRLI 622
+ A P PR++
Sbjct: 129 EVATTPEQFPRML 141
>UniRef50_Q0S4P5 Cluster: Acetolactate synthase large subunit; n=1;
Rhodococcus sp. RHA1|Rep: Acetolactate synthase large
subunit - Rhodococcus sp. (strain RHA1)
Length = 533
Score = 67.7 bits (158), Expect = 2e-10
Identities = 36/106 (33%), Positives = 54/106 (50%)
Frame = +2
Query: 224 DGNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLT 403
+G L +L GV+ VFGI G + A + ++ + R+EQ A YAA +T
Sbjct: 5 NGGQALVAALAAHGVDTVFGIPGTHNLAVYAALADSPIRSVLTRHEQGAGYAADGYARVT 64
Query: 404 GKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIG 541
GKPGVCL +GP +L+ A A + P++ I+ + P H G
Sbjct: 65 GKPGVCLTTTGPAILNAAAAAAQAWSDSVPVLFISPALPLTHPGRG 110
>UniRef50_A0VUP0 Cluster: Thiamine pyrophosphate enzyme TPP binding
domain protein; n=2; Rhodobacteraceae|Rep: Thiamine
pyrophosphate enzyme TPP binding domain protein -
Dinoroseobacter shibae DFL 12
Length = 546
Score = 67.7 bits (158), Expect = 2e-10
Identities = 33/95 (34%), Positives = 51/95 (53%)
Frame = +2
Query: 227 GNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTG 406
G L ESL GV+ V+G+ G A + + ++ R+EQAA + A G LTG
Sbjct: 7 GAQALVESLFSAGVDTVYGVPGEETTALMAALHDSEMAFVLCRHEQAAAFMAGVHGRLTG 66
Query: 407 KPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAG 511
+P CL GPG + + G+A+A ++ P++ I G
Sbjct: 67 RPAACLATLGPGATNLVTGVADATLDFVPMIAITG 101
>UniRef50_Q0CI52 Cluster: Putative uncharacterized protein; n=1;
Aspergillus terreus NIH2624|Rep: Putative
uncharacterized protein - Aspergillus terreus (strain
NIH 2624)
Length = 574
Score = 67.7 bits (158), Expect = 2e-10
Identities = 44/134 (32%), Positives = 70/134 (52%), Gaps = 3/134 (2%)
Frame = +2
Query: 221 IDGNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYL 400
+ G +LA+SLK GVE FG+ G + M + G++ + R+E A AA+A L
Sbjct: 14 LTGGDLLAQSLKTCGVEVAFGLHGGHLDAFLMGCEHIGIRLVDTRHETVAVQAAEAYSKL 73
Query: 401 TGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCP---EDHEAIGGFQEWPQVDS 571
T K GVC V + G + + G+A A + P++ I S P ++ ++ G + QV +
Sbjct: 74 TSKIGVCFVTANSGFSNGLPGLATALADRDPILCITSSPPLRDAENNSLQGIID--QVVA 131
Query: 572 SRMYCKYAARPPSP 613
SR K+A R +P
Sbjct: 132 SRPLTKFAHRMTNP 145
>UniRef50_Q2SEE0 Cluster: Thiamine pyrophosphate-requiring enzyme;
n=3; Proteobacteria|Rep: Thiamine
pyrophosphate-requiring enzyme - Hahella chejuensis
(strain KCTC 2396)
Length = 591
Score = 67.3 bits (157), Expect = 3e-10
Identities = 36/112 (32%), Positives = 60/112 (53%)
Frame = +2
Query: 227 GNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTG 406
G ++AE+L + GV +F + G + + AG++ I R+E +A +AA A LTG
Sbjct: 4 GGDLVAETLLEHGVGALFTLCGGHISPILSGCRKAGMQVIDARHEASAVFAADAYARLTG 63
Query: 407 KPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQ 562
PGV V +GPG+ + + + NAQ+ PL+++ G+ G Q+ Q
Sbjct: 64 IPGVAAVTAGPGVTNAVTALKNAQMAQSPLILLGGASATVLRGRGSLQDIDQ 115
>UniRef50_Q1IPP8 Cluster: Thiamine pyrophosphate enzyme-like
TPP-binding; n=2; cellular organisms|Rep: Thiamine
pyrophosphate enzyme-like TPP-binding - Acidobacteria
bacterium (strain Ellin345)
Length = 584
Score = 67.3 bits (157), Expect = 3e-10
Identities = 43/124 (34%), Positives = 69/124 (55%), Gaps = 3/124 (2%)
Frame = +2
Query: 236 ILAESLKKQGVEYVFGIVGIPV--IETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTGK 409
+L E L GV+ VFG+ G V + A+ L++I +R+E+AA +AA TG+
Sbjct: 8 LLIERLIHWGVDTVFGLPGDGVDGLFEALRTHQEKLRFIQVRHEEAAAFAACGYAKYTGR 67
Query: 410 PGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIG-GFQEWPQVDSSRMYC 586
GVC+ SGPG +H + G+ +A+ + P++ I G H+ IG +Q+ VD ++Y
Sbjct: 68 LGVCIATSGPGGIHLLNGLYDAKCDGQPVLAITGH--TFHDLIGTSYQQ--DVDLDKLYM 123
Query: 587 KYAA 598
AA
Sbjct: 124 DVAA 127
>UniRef50_Q05FL3 Cluster: Acetolactate synthase large subunit; n=1;
Candidatus Carsonella ruddii PV|Rep: Acetolactate
synthase large subunit - Carsonella ruddii (strain PV)
Length = 554
Score = 67.3 bits (157), Expect = 3e-10
Identities = 35/113 (30%), Positives = 60/113 (53%)
Frame = +2
Query: 215 MGIDGNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATG 394
M + I+ SL + VE++FG G V+ +G+K+I +R+EQ+A + A
Sbjct: 1 MKFSSSKIIINSLINENVEFIFGYPGGAVLNIYDEIFKSGIKHILVRHEQSAIHMADGYS 60
Query: 395 YLTGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQE 553
+ K GV +V SGPG +C+ G+A A ++ ++++ G + A FQE
Sbjct: 61 RSSNKIGVVIVTSGPGYTNCVTGIATASIDYSSIIILCGQVNKILIAQNSFQE 113
>UniRef50_A2QFR5 Cluster: Acetolactate synthase; n=3;
Aspergillus|Rep: Acetolactate synthase - Aspergillus
niger
Length = 645
Score = 67.3 bits (157), Expect = 3e-10
Identities = 43/140 (30%), Positives = 75/140 (53%), Gaps = 5/140 (3%)
Frame = +2
Query: 149 TCKLSQLVFRRSFCVSQKLNGS--MGIDGNTILAESLKKQGVEYVFGIVG---IPVIETA 313
T K S +F +S ++G G+ G +L E L +QGV+++FG G +P++++
Sbjct: 42 TEKQSPTTLVDTFLISAAMDGHDFAGLSGADVLCELLGRQGVKHIFGYPGGASLPLMDSL 101
Query: 314 MAFQSAGLKYIGMRNEQAACYAAQATGYLTGKPGVCLVVSGPGLLHCIGGMANAQVNCWP 493
+++ ++I +EQ A + A+ + KPGV +V SGPG + + M +A ++
Sbjct: 102 --YRAHRFEFILAHHEQGAGHMAEGYYRTSKKPGVVMVTSGPGSSNTVTPMLDALLDGTA 159
Query: 494 LVVIAGSCPEDHEAIGGFQE 553
+VVI G P + G FQE
Sbjct: 160 IVVICGQVPTASQGKGAFQE 179
>UniRef50_Q63PK8 Cluster: Acetolactate synthase isozyme II large
subunit; n=17; Proteobacteria|Rep: Acetolactate synthase
isozyme II large subunit - Burkholderia pseudomallei
(Pseudomonas pseudomallei)
Length = 567
Score = 66.9 bits (156), Expect = 4e-10
Identities = 43/137 (31%), Positives = 68/137 (49%), Gaps = 5/137 (3%)
Frame = +2
Query: 227 GNTILAESLKKQGVEYVFGIVGIPVIET--AMAFQSAGLKYIGMRNEQAACYAAQATGYL 400
G +L ++L VE VF + G + ++A ++ ++ I R+E AA A+A G L
Sbjct: 14 GARLLVDALLANHVERVFCVPGESFLAVLDSLADETERIRTIVCRHEAAAANMAEAVGKL 73
Query: 401 TGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQVDSSRM 580
TG+PG+ GPG H G+ A + P+++ G C +H FQE +D RM
Sbjct: 74 TGRPGIAFATRGPGATHASIGVHTAFQDSTPMILFIGQCAREHLDREAFQE---IDYRRM 130
Query: 581 Y---CKYAARPPSPRLI 622
+ K+ A+ PR I
Sbjct: 131 FGQLAKWVAQIDDPRRI 147
>UniRef50_Q2SJ09 Cluster: Thiamine pyrophosphate-requiring enzyme;
n=2; Gammaproteobacteria|Rep: Thiamine
pyrophosphate-requiring enzyme - Hahella chejuensis
(strain KCTC 2396)
Length = 584
Score = 66.9 bits (156), Expect = 4e-10
Identities = 39/115 (33%), Positives = 60/115 (52%), Gaps = 4/115 (3%)
Frame = +2
Query: 221 IDGNTILAESLKKQGVEYVFGIVG--IPVIETAMAFQS--AGLKYIGMRNEQAACYAAQA 388
I+ ++ L++ GV+YVFG+ G I + A+A G K + R+E A + A
Sbjct: 2 IENGDLILHYLERLGVKYVFGVPGGSIEPLYNALARSERRGGPKAVLARHESGAAFMADG 61
Query: 389 TGYLTGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQE 553
TGK GVC+ SGPG + + G+ANA + P++VI + +G FQE
Sbjct: 62 YARATGKLGVCISTSGPGATNLLTGVANAYADGIPMLVITAQPSIERFGLGAFQE 116
>UniRef50_Q84H41 Cluster: Sulfoacetaldehyde acetyltransferase; n=28;
Bacteria|Rep: Sulfoacetaldehyde acetyltransferase -
Alcaligenes xylosoxydans xylosoxydans (Achromobacter
xylosoxidans)
Length = 603
Score = 66.9 bits (156), Expect = 4e-10
Identities = 36/124 (29%), Positives = 64/124 (51%)
Frame = +2
Query: 245 ESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTGKPGVCL 424
E+ GV +FGI+G ++ F AG++ I + +EQ A + A ++G+ GV +
Sbjct: 24 ETCVANGVSEMFGIMGSAFMDAMDIFAPAGIRLIPVVHEQGAAHMADGYARVSGRHGVVI 83
Query: 425 VVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQVDSSRMYCKYAARP 604
+GPG+ +C+ G+A A P+V++ +GGFQE Q+ + + KY
Sbjct: 84 GQNGPGISNCVTGIAAAYWAHSPVVIVTPETGTMGMGLGGFQEANQLPMFQEFTKYQGHV 143
Query: 605 PSPR 616
+P+
Sbjct: 144 CNPK 147
>UniRef50_Q8ELJ0 Cluster: Acetolactate synthase large subunit; n=4;
Bacteria|Rep: Acetolactate synthase large subunit -
Oceanobacillus iheyensis
Length = 586
Score = 66.5 bits (155), Expect = 5e-10
Identities = 44/138 (31%), Positives = 70/138 (50%), Gaps = 8/138 (5%)
Frame = +2
Query: 230 NTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTGK 409
+ +L E L+ +GVE++FG+ G I + + + ++ +R+EQ A A A GY K
Sbjct: 6 SNLLVEYLEDRGVEHIFGLCGHTNIAFLSQLEKSSINFVNVRHEQIA--AHMADGYARAK 63
Query: 410 PGVCLVVS--GPGLLHCIGGMANAQVNCWPLVVIAGSCP------EDHEAIGGFQEWPQV 565
+V+S GPGL + G+ANA ++ P+VVIAG P H+ + + Q
Sbjct: 64 KETSVVLSHLGPGLTNAATGVANAALDNIPMVVIAGDVPSHYYGKHPHQEVNYHADGSQY 123
Query: 566 DSSRMYCKYAARPPSPRL 619
+ R + K A R P L
Sbjct: 124 EIYRPFVKRAWRVDRPDL 141
>UniRef50_A1SHD8 Cluster: Thiamine pyrophosphate enzyme domain
protein TPP-binding; n=4; Actinomycetales|Rep: Thiamine
pyrophosphate enzyme domain protein TPP-binding -
Nocardioides sp. (strain BAA-499 / JS614)
Length = 551
Score = 66.5 bits (155), Expect = 5e-10
Identities = 40/127 (31%), Positives = 68/127 (53%), Gaps = 3/127 (2%)
Frame = +2
Query: 191 VSQKLNGSMGIDGNTILAESLKKQGVEYVFGIVG---IPVIETAMAFQSAGLKYIGMRNE 361
+S ++NG G + + GVE +F + G P+ + A+ + L+ + +R+E
Sbjct: 1 MSTEVNGHAG----ELAVAVAQAHGVETMFTLSGAHVFPLYDGAVK-SATPLRLLDVRHE 55
Query: 362 QAACYAAQATGYLTGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIG 541
Q A +AA+ATG LT PG+ ++ +GPG+ + + +A AQ P+VV+ G P+ G
Sbjct: 56 QTAAFAAEATGKLTRVPGLAVLTAGPGVTNGLSAVAQAQFAGSPMVVVGGRAPQGRWGTG 115
Query: 542 GFQEWPQ 562
QE Q
Sbjct: 116 ALQELDQ 122
>UniRef50_Q8A6Q6 Cluster: Pyruvate dehydrogenase; n=6; Bacteria|Rep:
Pyruvate dehydrogenase - Bacteroides thetaiotaomicron
Length = 362
Score = 66.1 bits (154), Expect = 6e-10
Identities = 36/106 (33%), Positives = 58/106 (54%), Gaps = 1/106 (0%)
Frame = +2
Query: 239 LAESLKKQGVEYVFGIVGIPVIETAMAFQSAG-LKYIGMRNEQAACYAAQATGYLTGKPG 415
L ++L + GVE ++ + G + E A + +++I +R+E+ YAA A LTG+ G
Sbjct: 9 LIDTLVESGVERIYAVTGDSLNEVNEAVRKNNKIQWIHVRHEETGAYAAAAEAQLTGRIG 68
Query: 416 VCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQE 553
C SGPG +H I G+ +AQ + P++ IA + P FQE
Sbjct: 69 CCAGSSGPGHVHLINGLYDAQRSGAPVIAIASTIPSGEFGTEYFQE 114
>UniRef50_A7CXZ6 Cluster: Thiamine pyrophosphate protein TPP binding
domain protein; n=1; Opitutaceae bacterium TAV2|Rep:
Thiamine pyrophosphate protein TPP binding domain
protein - Opitutaceae bacterium TAV2
Length = 372
Score = 66.1 bits (154), Expect = 6e-10
Identities = 35/110 (31%), Positives = 59/110 (53%), Gaps = 1/110 (0%)
Frame = +2
Query: 227 GNTILAESLKKQGVEYVFGIVGIPVIETAMAFQ-SAGLKYIGMRNEQAACYAAQATGYLT 403
G T+L L++QG+ ++ GI G ++ A S +++I R+EQ A + AQ +T
Sbjct: 9 GATLLTRLLERQGIAHLPGIPGGAILPFYDALHDSPAIRHILARHEQGAGFIAQGMARVT 68
Query: 404 GKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQE 553
G+ C+ SGPG + + +A+A ++ PLV + G P+ FQE
Sbjct: 69 GRAAACVATSGPGATNLLTAIADAHLDSIPLVALTGQVPQTLIGTDAFQE 118
>UniRef50_Q0FGP6 Cluster: Acetolactate synthase II large subunit;
n=1; alpha proteobacterium HTCC2255|Rep: Acetolactate
synthase II large subunit - alpha proteobacterium
HTCC2255
Length = 545
Score = 65.7 bits (153), Expect = 8e-10
Identities = 36/109 (33%), Positives = 56/109 (51%), Gaps = 3/109 (2%)
Frame = +2
Query: 236 ILAESLKKQGVEYVFGIVG---IPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTG 406
+L E L QGV+ ++G+ G + V++ F + +I R+E AA + A+A G LTG
Sbjct: 9 LLVECLINQGVDKIYGVPGESYLSVLDALYDFNDK-INFISTRHESAASFMAEAYGKLTG 67
Query: 407 KPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQE 553
+ G+C V GPG + G+ A N P+++ G D FQE
Sbjct: 68 EVGICFVTRGPGATNASIGVHTAMQNSSPMILFIGQIGRDMTEREAFQE 116
>UniRef50_A5TSK5 Cluster: Acetolactate synthase; n=1; Fusobacterium
nucleatum subsp. polymorphum ATCC 10953|Rep:
Acetolactate synthase - Fusobacterium nucleatum subsp.
polymorphum ATCC 10953
Length = 573
Score = 65.7 bits (153), Expect = 8e-10
Identities = 39/114 (34%), Positives = 56/114 (49%), Gaps = 3/114 (2%)
Frame = +2
Query: 221 IDGNTILAESLKKQGVEYVFGIVG---IPVIETAMAFQSAGLKYIGMRNEQAACYAAQAT 391
I G IL E L + G+ +FG G IP+ + +F+ +K+ R+EQ A + A
Sbjct: 7 IKGARILLECLSRLGINEIFGYPGGAVIPIYDELYSFKE--IKHYFARHEQGAVHEADGY 64
Query: 392 GYLTGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQE 553
TGK G CL SGPG + + G+ A ++ PL+VI G FQE
Sbjct: 65 ARSTGKVGACLATSGPGATNLVTGIMTAHMDSIPLLVITGQVSSSLLGKDAFQE 118
>UniRef50_A3X9K6 Cluster: Acetolactate synthase-like TPP-requiring
enzyme; n=1; Roseobacter sp. MED193|Rep: Acetolactate
synthase-like TPP-requiring enzyme - Roseobacter sp.
MED193
Length = 573
Score = 65.7 bits (153), Expect = 8e-10
Identities = 35/112 (31%), Positives = 60/112 (53%), Gaps = 1/112 (0%)
Frame = +2
Query: 179 RSFCVSQKLNGSMGIDGNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRN 358
R + +KL + +G+ +A++LK G+ +V+ + G PV T A GL +G R+
Sbjct: 15 RPSVLRRKLARRLAPNGHQAIAQALKTGGITHVYSLPGNPVYATLAACVEIGLVVVGCRS 74
Query: 359 EQAACYAAQATGYLTGK-PGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAG 511
+ A AA A Y G+ + L PG+ + + +++A N WP+V+IAG
Sbjct: 75 QSGALSAAMAHNYQAGRFCALALCSPAPGVTNSVTALSDAMSNQWPMVLIAG 126
>UniRef50_Q02137 Cluster: Acetolactate synthase large subunit; n=71;
Bacilli|Rep: Acetolactate synthase large subunit -
Lactococcus lactis subsp. lactis (Streptococcus lactis)
Length = 575
Score = 65.7 bits (153), Expect = 8e-10
Identities = 40/125 (32%), Positives = 67/125 (53%), Gaps = 3/125 (2%)
Frame = +2
Query: 227 GNTILAESLKKQGVEYVFGIVG---IPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGY 397
G+ ++ ++LK+ GVE +FG G +P+ + F+ G+++I R+EQ A + A+
Sbjct: 12 GSQLVLQTLKELGVEIIFGYPGGAMLPLYDAIHNFE--GIQHILARHEQGATHEAEGYAK 69
Query: 398 LTGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQVDSSR 577
+GK GV +V SGPG + + G+A+A ++ PL+V G FQE V +
Sbjct: 70 SSGKVGVVVVTSGPGATNAVTGIADAYLDSVPLLVFTGQVGPLSIGKDAFQEADTVGITA 129
Query: 578 MYCKY 592
KY
Sbjct: 130 PITKY 134
>UniRef50_Q28W58 Cluster: Thiamine pyrophosphate enzyme-like
TPP-binding; n=4; Rhodobacterales|Rep: Thiamine
pyrophosphate enzyme-like TPP-binding - Jannaschia sp.
(strain CCS1)
Length = 538
Score = 65.3 bits (152), Expect = 1e-09
Identities = 39/109 (35%), Positives = 48/109 (44%)
Frame = +2
Query: 227 GNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTG 406
G ILA+ L GVE VF + G + + I R E A A+A G +TG
Sbjct: 6 GGKILADRLALHGVERVFSVPGESFLAALDGLYDHDIPNIVCRQEGGAAMMAEAHGKMTG 65
Query: 407 KPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQE 553
PGV V GPG + G+ A + PLV G P H G FQE
Sbjct: 66 TPGVLFVTRGPGATNASAGLHIAMHDATPLVCFVGQIPLKHRDRGVFQE 114
>UniRef50_Q1N3D1 Cluster: Pyruvate oxidase; n=2;
Gammaproteobacteria|Rep: Pyruvate oxidase - Oceanobacter
sp. RED65
Length = 555
Score = 65.3 bits (152), Expect = 1e-09
Identities = 35/117 (29%), Positives = 63/117 (53%), Gaps = 1/117 (0%)
Frame = +2
Query: 236 ILAESLKKQGVEYVFGIVGIPVIETAMAFQSA-GLKYIGMRNEQAACYAAQATGYLTGKP 412
+ + LK+ GV Y+FGI G + + + + G+++I +++E+A AA LTGK
Sbjct: 6 LFVKVLKQHGVRYLFGIPGDAINDLMESVRKEEGIEFIQVKHEEAGALAASVQAKLTGKL 65
Query: 413 GVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQVDSSRMY 583
C+ SGPG +H + G+ +A+++ P++ I G + QE VD R++
Sbjct: 66 TACVGTSGPGAIHLLNGLYDAKMDHAPVLAITGQVETQYMGTNYHQE---VDLERLF 119
>UniRef50_A6BEJ7 Cluster: Acetolactate synthase; n=3;
Clostridiales|Rep: Acetolactate synthase - Dorea
longicatena DSM 13814
Length = 564
Score = 65.3 bits (152), Expect = 1e-09
Identities = 38/103 (36%), Positives = 57/103 (55%), Gaps = 2/103 (1%)
Frame = +2
Query: 203 LNGSMGIDGNTILAESLKKQGVEYVFGIVGIPVIET--AMAFQSAGLKYIGMRNEQAACY 376
+NG M + G+ I+ E LK+QGV+ VFG G ++ + + +I +EQ A +
Sbjct: 1 MNG-MQLTGSQIVIECLKEQGVDTVFGYPGGAILNVYDELYKHKDEITHILTSHEQGAAH 59
Query: 377 AAQATGYLTGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVI 505
AA TGK GVCL SGPG + + G+A A ++ P+V I
Sbjct: 60 AADGYARATGKVGVCLATSGPGATNLVTGIATAYMDSIPVVAI 102
>UniRef50_A4R4K6 Cluster: Putative uncharacterized protein; n=2;
Pezizomycotina|Rep: Putative uncharacterized protein -
Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 573
Score = 65.3 bits (152), Expect = 1e-09
Identities = 39/100 (39%), Positives = 53/100 (53%), Gaps = 3/100 (3%)
Frame = +2
Query: 224 DGNT--ILAESLKKQGVEYVFGIVGIPVIETAMA-FQSAGLKYIGMRNEQAACYAAQATG 394
DG+T I+ SLK GV+ VFGI G + A + ++ + R+EQ A + A G
Sbjct: 7 DGDTVQIVINSLKAAGVKVVFGIPGAKIDSLFNALYDEESIRLVVCRHEQNAAFMAGVVG 66
Query: 395 YLTGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGS 514
LT PGVC+V SGPG + G+ A P+V I GS
Sbjct: 67 KLTNVPGVCIVTSGPGTSNLPTGLITATDEGSPMVAIVGS 106
>UniRef50_O05031 Cluster: Uncharacterized protein HI0737; n=11;
Haemophilus influenzae|Rep: Uncharacterized protein
HI0737 - Haemophilus influenzae
Length = 265
Score = 65.3 bits (152), Expect = 1e-09
Identities = 37/109 (33%), Positives = 52/109 (47%)
Frame = +2
Query: 227 GNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTG 406
G ++ LK V +FG G ++ T A AGL ++ RNEQ AA TG
Sbjct: 3 GAQLIMACLKAHHVTTLFGYPGGAIMPTYDALYDAGLDHLLCRNEQGTAMAAIGYARSTG 62
Query: 407 KPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQE 553
K GVC+ SGPG + + G+ +A ++ P+V I G FQE
Sbjct: 63 KVGVCIATSGPGATNLVIGLGDAMMDSIPVVTITGQVASPLIGTDAFQE 111
>UniRef50_Q6N658 Cluster: Possible benzaldehyde lyase; n=2;
Rhodopseudomonas palustris|Rep: Possible benzaldehyde
lyase - Rhodopseudomonas palustris
Length = 600
Score = 64.9 bits (151), Expect = 1e-09
Identities = 45/136 (33%), Positives = 66/136 (48%), Gaps = 4/136 (2%)
Frame = +2
Query: 227 GNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTG 406
G +LA++LK GV F + G + + I R+E +A +AA A TG
Sbjct: 30 GGQLLAKTLKAAGVSQAFALHGGHLEALLKGCIEEEIALIDFRHESSAGHAADAYARATG 89
Query: 407 KPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCP----EDHEAIGGFQEWPQVDSS 574
K GVC+V +GPG + + M NAQ++ P++ I G+ P E + GG QV +
Sbjct: 90 KLGVCIVTAGPGFTNVLSAMTNAQLDGSPVLFIVGAPPLREVETNPLQGGID---QVAMA 146
Query: 575 RMYCKYAARPPSPRLI 622
R K+A PS I
Sbjct: 147 RPAVKWAFSIPSTERI 162
>UniRef50_Q2S0N1 Cluster: Acetolactate synthase, large subunit,
biosynthetic type; n=1; Salinibacter ruber DSM
13855|Rep: Acetolactate synthase, large subunit,
biosynthetic type - Salinibacter ruber (strain DSM
13855)
Length = 596
Score = 64.9 bits (151), Expect = 1e-09
Identities = 39/126 (30%), Positives = 63/126 (50%), Gaps = 2/126 (1%)
Frame = +2
Query: 221 IDGNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKY--IGMRNEQAACYAAQATG 394
+ G+ I +L+++GV+ VFG G VI+ A + Y + +R+EQ +AA+
Sbjct: 25 LKGSEIFVRALEEEGVDRVFGHPGGAVIKIYDAMERIQPSYDHVLVRHEQGGTHAAEGYA 84
Query: 395 YLTGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQVDSS 574
TG+ G L SGPG + + G+A+A ++ P+VV G P FQE +
Sbjct: 85 KATGRVGTMLATSGPGATNTVTGIADAYLDSVPIVVFTGQVPTHLIGNDSFQETDTTGVT 144
Query: 575 RMYCKY 592
R K+
Sbjct: 145 RSITKH 150
>UniRef50_A6UGS0 Cluster: Thiamine pyrophosphate protein domain
protein TPP-binding; n=3; Bacteria|Rep: Thiamine
pyrophosphate protein domain protein TPP-binding -
Sinorhizobium medicae WSM419
Length = 605
Score = 64.9 bits (151), Expect = 1e-09
Identities = 40/122 (32%), Positives = 71/122 (58%), Gaps = 2/122 (1%)
Frame = +2
Query: 224 DGNTILAESLKKQGVEYVFGIVG--IPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGY 397
+ + IL E+L + VE VFG+ G I I A+ + ++++ +R+EQ+A + A A
Sbjct: 3 NASDILIETLIEWKVEVVFGLPGDGINGIMEALRRRQDRIRFVSVRHEQSAAFMACAYAK 62
Query: 398 LTGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQVDSSR 577
TG+ GVCL SGPG + + G+ +A+++ P++ I G + H+ I F + VD +R
Sbjct: 63 FTGRLGVCLATSGPGGTNLLTGLYDAKLDQMPVLAITGM--QYHDLIETFSQ-QDVDLTR 119
Query: 578 MY 583
++
Sbjct: 120 VF 121
>UniRef50_UPI0000F347A9 Cluster: UPI0000F347A9 related cluster; n=1;
Bos taurus|Rep: UPI0000F347A9 UniRef100 entry - Bos
Taurus
Length = 442
Score = 64.5 bits (150), Expect = 2e-09
Identities = 36/124 (29%), Positives = 60/124 (48%)
Frame = +2
Query: 227 GNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTG 406
G +A LK GV ++F +VG + +A + + + +E A +A A LTG
Sbjct: 2 GGENVAAVLKAHGVRFLFTLVGRHISPLLVACEKPDICVVDTHHEVTAVFATDAVARLTG 61
Query: 407 KPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQVDSSRMYC 586
GV V +GPGL + + + NAQ+ P++++ G+ + G Q Q+ R C
Sbjct: 62 TMGVAAVTAGPGLTNAVTAVKNAQIAQSPVLLLGGAANTLLQNRGALQAVDQIALFRPLC 121
Query: 587 KYAA 598
K+ A
Sbjct: 122 KFCA 125
>UniRef50_Q8EN64 Cluster: Acetolactate synthase; n=24; cellular
organisms|Rep: Acetolactate synthase - Oceanobacillus
iheyensis
Length = 573
Score = 64.5 bits (150), Expect = 2e-09
Identities = 35/113 (30%), Positives = 59/113 (52%), Gaps = 2/113 (1%)
Frame = +2
Query: 221 IDGNTILAESLKKQGVEYVFGIVGIPV--IETAMAFQSAGLKYIGMRNEQAACYAAQATG 394
+ G + ++L++ VE VFG G V I A+ +++ R+EQ + +AA+
Sbjct: 16 VTGADLFVQALERANVEVVFGYPGGAVLPIYDALHRNQTSFEHVLSRHEQGSIHAAEGYA 75
Query: 395 YLTGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQE 553
++GKPGV + SGPG + I G+ +A ++ PLV+ G + FQE
Sbjct: 76 RVSGKPGVVIATSGPGATNLITGITDAMMDSIPLVIFTGQVAKGVIGTDAFQE 128
>UniRef50_Q7WA22 Cluster: Acetolactate synthase large subunit; n=9;
cellular organisms|Rep: Acetolactate synthase large
subunit - Bordetella parapertussis
Length = 577
Score = 64.5 bits (150), Expect = 2e-09
Identities = 42/127 (33%), Positives = 61/127 (48%), Gaps = 3/127 (2%)
Frame = +2
Query: 224 DGNTILAESLKKQGVEYVFGIVG---IPVIETAMAFQSAGLKYIGMRNEQAACYAAQATG 394
+G IL + L+ G VF I G +P I+ + A + I R E A Y A+A G
Sbjct: 10 NGGQILMQQLRVHGARRVFMIPGESYLPCIDALNEHRGA-IDAIVCRQESGAAYMAEAYG 68
Query: 395 YLTGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQVDSS 574
LTG+PG+C V GPG + G+ A + P+++ G D FQE +D
Sbjct: 69 KLTGEPGICFVTRGPGATNASIGVHTAYQDSTPMILFIGQVGNDFMEREAFQE---IDYR 125
Query: 575 RMYCKYA 595
RM+ + A
Sbjct: 126 RMFGQMA 132
>UniRef50_A1VPE3 Cluster: Transcriptional regulator, Fis family;
n=3; Proteobacteria|Rep: Transcriptional regulator, Fis
family - Polaromonas naphthalenivorans (strain CJ2)
Length = 580
Score = 64.5 bits (150), Expect = 2e-09
Identities = 37/109 (33%), Positives = 58/109 (53%), Gaps = 3/109 (2%)
Frame = +2
Query: 236 ILAESLKKQGVEYVFGIVG---IPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTG 406
+L + L QGV + FG+ G + V++ A + +++I R E A + A+A G LTG
Sbjct: 25 LLVDCLLAQGVTHAFGVPGESYLAVLDGLHARRDQ-IRFITCRQEGGAAFMAEAHGKLTG 83
Query: 407 KPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQE 553
+PGVC+V GPG + G+ A + P+V++ G D FQE
Sbjct: 84 RPGVCMVTRGPGATNASIGVHTAFQDSTPMVLLVGDVASDCRDREAFQE 132
>UniRef50_O26576 Cluster: Pyruvate dehydrogenase / acetolactate
synthase; n=1; Methanothermobacter thermautotrophicus
str. Delta H|Rep: Pyruvate dehydrogenase / acetolactate
synthase - Methanobacterium thermoautotrophicum
Length = 553
Score = 64.5 bits (150), Expect = 2e-09
Identities = 38/127 (29%), Positives = 62/127 (48%), Gaps = 1/127 (0%)
Frame = +2
Query: 236 ILAESLKKQGVEYVFGIVGIPVIETAMAFQ-SAGLKYIGMRNEQAACYAAQATGYLTGKP 412
+ L G++YVFGI G + A + + ++YI +R+E AA + A + G LTG+P
Sbjct: 57 VFISQLAAWGLKYVFGIPGTSTLGLVDALRRNDEIRYIQVRHEAAAAFMASSYGKLTGQP 116
Query: 413 GVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQVDSSRMYCKY 592
VC+ V+GP + I G+ +A ++ P++ + G G QE Q + Y
Sbjct: 117 AVCMAVAGPRASNLITGLLDAALDRAPVLAVTGHVETYRIGTGASQEIDQHSLFESFSVY 176
Query: 593 AARPPSP 613
SP
Sbjct: 177 NMTLVSP 183
>UniRef50_UPI00015BB008 Cluster: acetolactate synthase, large
subunit; n=1; Ignicoccus hospitalis KIN4/I|Rep:
acetolactate synthase, large subunit - Ignicoccus
hospitalis KIN4/I
Length = 577
Score = 64.1 bits (149), Expect = 3e-09
Identities = 40/129 (31%), Positives = 62/129 (48%), Gaps = 1/129 (0%)
Frame = +2
Query: 239 LAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTGK-PG 415
L ESL+++G++ FGI G + ++ I MR+EQ A +AA A G + K PG
Sbjct: 7 LLESLEREGLKVAFGIPGSANLGLYEKIPDHDVEVILMRHEQGAAHAADAYGRVKRKVPG 66
Query: 416 VCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQVDSSRMYCKYA 595
V SGPG + + G+A A ++ P++ + G P FQE V + K++
Sbjct: 67 VAFATSGPGATNLVTGLATAYMDSAPMIAVTGQVPTVVMGRDAFQETDVVGVTMPITKHS 126
Query: 596 ARPPSPRLI 622
P I
Sbjct: 127 FLVRKPEQI 135
>UniRef50_Q74H96 Cluster: Pyruvate oxidase; n=1; Lactobacillus
johnsonii|Rep: Pyruvate oxidase - Lactobacillus
johnsonii
Length = 566
Score = 64.1 bits (149), Expect = 3e-09
Identities = 34/116 (29%), Positives = 62/116 (53%), Gaps = 2/116 (1%)
Frame = +2
Query: 221 IDGNTILAESLKKQGVEYVFGIVGIPVIETAMAFQS--AGLKYIGMRNEQAACYAAQATG 394
I G+ + + L G+++++G G T A + +K+I +R+E+A AA A
Sbjct: 4 ISGSDAMFQVLYDWGIDHIYGFPGGSFDSTMNAIHNWRDKIKFIEVRHEEAGALAASAEY 63
Query: 395 YLTGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQ 562
++GK GVC +GPG +H + G+ +A+ + P+V I + P + I FQ + +
Sbjct: 64 KISGKVGVCFGSAGPGAVHLMNGLYDAKYDKTPMVAIVANVPTSRQDIDFFQAFDE 119
>UniRef50_Q2AIK5 Cluster: Thiamine pyrophosphate enzyme, C-terminal
TPP-binding:Thiamine pyrophosphate enzyme, central
region:Thiamine pyrophosphate enzyme, N- terminal TPP
binding region; n=1; Halothermothrix orenii H 168|Rep:
Thiamine pyrophosphate enzyme, C-terminal
TPP-binding:Thiamine pyrophosphate enzyme, central
region:Thiamine pyrophosphate enzyme, N- terminal TPP
binding region - Halothermothrix orenii H 168
Length = 534
Score = 64.1 bits (149), Expect = 3e-09
Identities = 32/102 (31%), Positives = 55/102 (53%)
Frame = +2
Query: 215 MGIDGNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATG 394
MG + ++ E L GV++++G G +++ + + +K ++E A + A A
Sbjct: 1 MGQKVSEVIIEQLHNFGVKHIYGYAGDTILKFFSKLKGSPVKLFTTKHESTAGFMASAEA 60
Query: 395 YLTGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCP 520
LTG GVC+ SGPG + I G+A+A + PL++I G P
Sbjct: 61 KLTGNLGVCIAHSGPGTTNIINGIADAYSDRVPLLLITGQVP 102
>UniRef50_Q8PT77 Cluster: Acetolactate synthase; n=4; cellular
organisms|Rep: Acetolactate synthase - Methanosarcina
mazei (Methanosarcina frisia)
Length = 584
Score = 64.1 bits (149), Expect = 3e-09
Identities = 32/110 (29%), Positives = 59/110 (53%)
Frame = +2
Query: 221 IDGNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYL 400
++G +L + L+ GV+++FG G ++ A + + ++ I NEQ+A ++A
Sbjct: 18 MNGAEVLIKCLEDLGVKHIFGYTGAAILPVFHALRHSDIEIIVNSNEQSAAFSAAGYSRS 77
Query: 401 TGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQ 550
+ + GV +V SGP + + + +A+A + PL+V AG PE FQ
Sbjct: 78 SNRVGVAIVTSGPAITNTLTSVADAYGDSIPLLVFAGQVPEHKIGTDSFQ 127
>UniRef50_Q2NI87 Cluster: Acetolactate synthase; n=2; Methanosphaera
stadtmanae DSM 3091|Rep: Acetolactate synthase -
Methanosphaera stadtmanae (strain DSM 3091)
Length = 562
Score = 64.1 bits (149), Expect = 3e-09
Identities = 35/109 (32%), Positives = 57/109 (52%)
Frame = +2
Query: 227 GNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTG 406
G+ +L + LK+ G +FG G ++ A + + +I +R+EQAA +AA +G
Sbjct: 3 GSELLIKKLKENGTTTIFGYPGGVLLPFYDALCESDIDHILVRHEQAAVHAADGYSRASG 62
Query: 407 KPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQE 553
K GVCL SGPG + G+A A ++ P++ + G + FQE
Sbjct: 63 KIGVCLATSGPGATNITTGIATAHMDSSPIIALTGQVATNLIGKDVFQE 111
>UniRef50_Q6D0F1 Cluster: Acetolactate synthase isozyme I large
subunit; n=5; Bacteria|Rep: Acetolactate synthase
isozyme I large subunit - Erwinia carotovora subsp.
atroseptica (Pectobacterium atrosepticum)
Length = 554
Score = 63.7 bits (148), Expect = 3e-09
Identities = 37/114 (32%), Positives = 58/114 (50%), Gaps = 1/114 (0%)
Frame = +2
Query: 215 MGIDGNTILAESLKKQGVEYVFGIVGIPVIETAMAF-QSAGLKYIGMRNEQAACYAAQAT 391
M G ++ L++QG+ V GI G + A QS ++++ R+EQ A + AQ
Sbjct: 1 MRYTGAQLIVRLLEQQGITTVAGIPGGAALPLYDALSQSQTIRHVLARHEQGAGFMAQGM 60
Query: 392 GYLTGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQE 553
+G+ VC+ SGPG + I +A+A+++ PLV I G P FQE
Sbjct: 61 ARASGRAAVCMASSGPGATNLITAIADAKLDSIPLVCITGQVPSSMIGTDAFQE 114
>UniRef50_Q41EN3 Cluster: Pyruvate decarboxylase; n=1;
Exiguobacterium sibiricum 255-15|Rep: Pyruvate
decarboxylase - Exiguobacterium sibiricum 255-15
Length = 541
Score = 63.7 bits (148), Expect = 3e-09
Identities = 31/89 (34%), Positives = 51/89 (57%)
Frame = +2
Query: 245 ESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTGKPGVCL 424
+ L+ +GV ++FG+ G I A + + +I R+E A + A G L+G+PGVCL
Sbjct: 9 QCLEAEGVTHIFGVPGEENITLLEAISKSDITFITTRHETNAAFMASMFGRLSGRPGVCL 68
Query: 425 VVSGPGLLHCIGGMANAQVNCWPLVVIAG 511
GPG + + G+A+A ++ P+V I G
Sbjct: 69 STLGPGATNMMTGIASATMDHSPVVAITG 97
>UniRef50_Q168P2 Cluster: Acetohydroxy acid synthase large subunit,
putative; n=9; Rhodobacteraceae|Rep: Acetohydroxy acid
synthase large subunit, putative - Roseobacter
denitrificans (strain ATCC 33942 / OCh 114)
(Erythrobactersp. (strain OCh 114)) (Roseobacter
denitrificans)
Length = 530
Score = 63.7 bits (148), Expect = 3e-09
Identities = 34/102 (33%), Positives = 57/102 (55%)
Frame = +2
Query: 239 LAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTGKPGV 418
++ LK +GV+ +FGI G+ E + AG+ ++ R+EQ A + A TGKPGV
Sbjct: 9 ISHMLKDRGVDVIFGIPGVHNQEMYRGIEEAGITHVLARHEQGAGFMADGYARATGKPGV 68
Query: 419 CLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGG 544
V++GPGL + + M A + ++V++ SC ++ A G
Sbjct: 69 AYVITGPGLCNAMTPMGQAYSDSVSMLVLS-SCLDEVAARKG 109
>UniRef50_Q5IWY3 Cluster: Plastid acetolactate synthase large
subunit; n=1; Prototheca wickerhamii|Rep: Plastid
acetolactate synthase large subunit - Prototheca
wickerhamii
Length = 219
Score = 63.7 bits (148), Expect = 3e-09
Identities = 34/108 (31%), Positives = 60/108 (55%), Gaps = 1/108 (0%)
Frame = +2
Query: 227 GNTILAESLKKQGVEYVFGIVGIPVIETAMAF-QSAGLKYIGMRNEQAACYAAQATGYLT 403
G+ IL ++L+++GV+ +F G +E A +S ++ I R+EQ +AA+ ++
Sbjct: 103 GSDILVQALEREGVDVLFAYPGGASMEIHQALTRSHTVRNILCRHEQGEVFAAEGYAKVS 162
Query: 404 GKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGF 547
G+ GVC+ SGPG + + G+A+A ++ +V I G P GF
Sbjct: 163 GRVGVCIATSGPGATNLVTGLADALMDSVAMVAITGQVPRSLIGSDGF 210
>UniRef50_O08353 Cluster: Probable acetolactate synthase large
subunit; n=12; Archaea|Rep: Probable acetolactate
synthase large subunit - Methanococcus aeolicus
Length = 599
Score = 63.7 bits (148), Expect = 3e-09
Identities = 35/111 (31%), Positives = 58/111 (52%)
Frame = +2
Query: 221 IDGNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYL 400
++G + ++L+ + VE +FG G ++ A + L ++ R+EQAA +AA
Sbjct: 1 MNGAEAMIKALEAEKVEILFGYPGGALLPFYDALHHSDLIHLLTRHEQAAAHAADGYARA 60
Query: 401 TGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQE 553
+GK GVC+ SGPG + + G+A A + P+V + G P FQE
Sbjct: 61 SGKVGVCIGTSGPGATNLVTGVATAHSDSSPMVALTGQVPTKLIGNDAFQE 111
>UniRef50_Q3SL06 Cluster: Acetolactate synthase large subunit; n=1;
Thiobacillus denitrificans ATCC 25259|Rep: Acetolactate
synthase large subunit - Thiobacillus denitrificans
(strain ATCC 25259)
Length = 553
Score = 63.3 bits (147), Expect = 4e-09
Identities = 32/113 (28%), Positives = 56/113 (49%)
Frame = +2
Query: 215 MGIDGNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATG 394
M I + ++ L++ G+ +VFG+ G ++ + A L+ + +++EQ A + A
Sbjct: 1 MNISVSELIVRYLERLGIGHVFGMPGAHILPIYDRLRDASLRTVLVKHEQGAAFMAGGEA 60
Query: 395 YLTGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQE 553
+ +P C+ SGPG + I G+ANA P++ I G GG QE
Sbjct: 61 RVARRPSACIATSGPGATNLITGIANAYAERLPVLAITGETSTYIFGRGGLQE 113
>UniRef50_A5V6Y6 Cluster: Thiamine pyrophosphate enzyme domain
protein TPP-binding; n=4; Alphaproteobacteria|Rep:
Thiamine pyrophosphate enzyme domain protein TPP-binding
- Sphingomonas wittichii RW1
Length = 547
Score = 63.3 bits (147), Expect = 4e-09
Identities = 44/138 (31%), Positives = 64/138 (46%), Gaps = 5/138 (3%)
Frame = +2
Query: 215 MGIDGNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAG--LKYIGMRNEQAACYAAQA 388
M + G L + G + +FG+ G + A AG L+ G R+EQ A Y A
Sbjct: 1 MTMTGAQALLGQILANGTDTIFGLPGGQLDHFFDAMHKAGDKLRLFGTRHEQGAAYMAFG 60
Query: 389 TGYLTGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPED--HEAIGGFQEWP- 559
TGKPGV VV GPG+L+ + +A P++ + G P + IG E P
Sbjct: 61 YARSTGKPGVYTVVPGPGVLNTTAALCSAYATNAPVLCLTGQIPSAGIGKGIGYLHELPD 120
Query: 560 QVDSSRMYCKYAARPPSP 613
Q+ + R K+A R +P
Sbjct: 121 QLATMRTLTKWADRAMTP 138
>UniRef50_Q5LQV0 Cluster: Benzaldehyde lyase, putative; n=1;
Silicibacter pomeroyi|Rep: Benzaldehyde lyase, putative
- Silicibacter pomeroyi
Length = 576
Score = 62.9 bits (146), Expect = 6e-09
Identities = 41/134 (30%), Positives = 61/134 (45%), Gaps = 1/134 (0%)
Frame = +2
Query: 203 LNGSMGIDGNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAA 382
+N I G +LA +LK++GVE+ F + G F + I +EQ A + A
Sbjct: 1 MNAHTRIRGGALLARALKEKGVEHAFTLAGGFCNPALEGFMECQMPIINCPHEQVAGHLA 60
Query: 383 QATGYLTGKPGVCLVVSGP-GLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWP 559
+T KP VCLV GP G + + M A P++ I GS + GGF+E
Sbjct: 61 DGHSRITRKPSVCLV--GPEGFANAVPAMLEAWGERTPVIFITGSSTLKRQGAGGFKEID 118
Query: 560 QVDSSRMYCKYAAR 601
V + KY+ +
Sbjct: 119 DVAIAAPLTKYSVQ 132
>UniRef50_A3JPU7 Cluster: Acetolactate synthase, large subunit,
putative; n=2; Rhodobacterales|Rep: Acetolactate
synthase, large subunit, putative - Rhodobacterales
bacterium HTCC2150
Length = 553
Score = 62.9 bits (146), Expect = 6e-09
Identities = 35/112 (31%), Positives = 52/112 (46%), Gaps = 2/112 (1%)
Frame = +2
Query: 224 DGNTILAESLKKQGVEYVFGIVGIPVIET--AMAFQSAGLKYIGMRNEQAACYAAQATGY 397
+G +L LK G ++ FG+ G + + L +IG RNE Y A+A G
Sbjct: 10 NGGHLLVACLKNLGAKHAFGVPGESYLAALDGLFDTKENLPFIGSRNEGGGAYMAEAYGK 69
Query: 398 LTGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQE 553
LTG PG+C V GPG + G+ +A P+++ G + FQE
Sbjct: 70 LTGTPGICFVTRGPGATNASIGVHSAMQASTPMLLFIGQVGAELRDREAFQE 121
>UniRef50_P07003 Cluster: Pyruvate dehydrogenase [cytochrome] (EC
1.2.2.2) (Pyruvate oxidase) (POX) (Pyruvate
dehydrogenase [Ubiquinone]) [Contains: Alpha-peptide];
n=91; Bacteria|Rep: Pyruvate dehydrogenase [cytochrome]
(EC 1.2.2.2) (Pyruvate oxidase) (POX) (Pyruvate
dehydrogenase [Ubiquinone]) [Contains: Alpha-peptide] -
Escherichia coli (strain K12)
Length = 572
Score = 62.9 bits (146), Expect = 6e-09
Identities = 38/129 (29%), Positives = 63/129 (48%), Gaps = 1/129 (0%)
Frame = +2
Query: 239 LAESLKKQGVEYVFGIVGIPVIETAMAFQSAG-LKYIGMRNEQAACYAAQATGYLTGKPG 415
+A++L+ GV+ ++G+ G + + + G ++++ R+E+ A +AA A L+G+
Sbjct: 9 IAKTLESAGVKRIWGVTGDSLNGLSDSLNRMGTIEWMSTRHEEVAAFAAGAEAQLSGELA 68
Query: 416 VCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQVDSSRMYCKYA 595
VC GPG LH I G+ + N P++ IA P G FQE + R Y
Sbjct: 69 VCAGSCGPGNLHLINGLFDCHRNHVPVLAIAAHIPSSEIGSGYFQETHPQELFRECSHYC 128
Query: 596 ARPPSPRLI 622
SP I
Sbjct: 129 ELVSSPEQI 137
>UniRef50_A4AL48 Cluster: Putative uncharacterized protein; n=1;
marine actinobacterium PHSC20C1|Rep: Putative
uncharacterized protein - marine actinobacterium
PHSC20C1
Length = 560
Score = 62.5 bits (145), Expect = 8e-09
Identities = 33/110 (30%), Positives = 53/110 (48%), Gaps = 3/110 (2%)
Frame = +2
Query: 212 SMGIDGNTI---LAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAA 382
S G+D N + L+ G++ +FGI G +E G++ + R+EQ A Y +
Sbjct: 19 SGGVDVNNAGLAIMTVLRNYGIDTIFGIPGTHNLEFYRPLSELGIRPVTTRHEQGASYGS 78
Query: 383 QATGYLTGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHE 532
TG PGV + SGPGLL+ + G A P+++++ E E
Sbjct: 79 DGWSQQTGLPGVVITTSGPGLLNALSGAGTAYCESRPMILLSPGVAEGSE 128
>UniRef50_UPI000050F94C Cluster: COG0028: Thiamine
pyrophosphate-requiring enzymes [acetolactate synthase,
pyruvate dehydrogenase (cytochrome), glyoxylate
carboligase, phosphonopyruvate decarboxylase]; n=1;
Brevibacterium linens BL2|Rep: COG0028: Thiamine
pyrophosphate-requiring enzymes [acetolactate synthase,
pyruvate dehydrogenase (cytochrome), glyoxylate
carboligase, phosphonopyruvate decarboxylase] -
Brevibacterium linens BL2
Length = 562
Score = 62.1 bits (144), Expect = 1e-08
Identities = 34/102 (33%), Positives = 52/102 (50%)
Frame = +2
Query: 227 GNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTG 406
G ++A +L GV+ +FGI G +E G++ I R+EQ A Y A ++G
Sbjct: 18 GRAVIA-TLAAHGVDTIFGIPGTHNLEFYRHLSEFGIRAITPRHEQGAGYGADGYFLVSG 76
Query: 407 KPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHE 532
KPGV + SGPGL + I A A P+++++ P E
Sbjct: 77 KPGVVITTSGPGLTNVITAAATAYAESRPMLILSPGVPTGME 118
>UniRef50_Q1ILZ1 Cluster: Acetolactate synthase; n=5; cellular
organisms|Rep: Acetolactate synthase - Acidobacteria
bacterium (strain Ellin345)
Length = 571
Score = 62.1 bits (144), Expect = 1e-08
Identities = 32/109 (29%), Positives = 56/109 (51%)
Frame = +2
Query: 227 GNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTG 406
G I+ E L+++G + FG G ++ T A + + + ++ +R+EQ A + A ++G
Sbjct: 7 GAQIIWECLEREGTKIAFGYPGGAILPTYDALKHSSIHHVLVRHEQGATHMADGYARVSG 66
Query: 407 KPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQE 553
GV + SGPG + + G+A A ++ P+V I G FQE
Sbjct: 67 GVGVAIATSGPGATNMVTGIATAMLDSSPIVCITGQVGSKLIGTDAFQE 115
>UniRef50_Q13I72 Cluster: Putative pyruvate decarboxylase; n=1;
Burkholderia xenovorans LB400|Rep: Putative pyruvate
decarboxylase - Burkholderia xenovorans (strain LB400)
Length = 590
Score = 62.1 bits (144), Expect = 1e-08
Identities = 35/108 (32%), Positives = 58/108 (53%), Gaps = 1/108 (0%)
Frame = +2
Query: 239 LAESLKKQGVEYVFGIVGIPVIETAMA-FQSAGLKYIGMRNEQAACYAAQATGYLTGKPG 415
+ +L+ +GV+ +FG+ G VI+ A + + +++ +R+E A A LTG+P
Sbjct: 26 IVNALRAEGVDALFGMPGGHVIQIYDALYDTPEIRHYLVRHEGTAASMAAGYAQLTGRPA 85
Query: 416 VCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWP 559
VC+V +GPG + + +A A V P+V+IAG G QE P
Sbjct: 86 VCVVTAGPGATNVLTAVAEAHVASLPMVIIAGRGATTTSYRGASQEVP 133
>UniRef50_Q6PST7 Cluster: CidC; n=30; Bacillales|Rep: CidC -
Staphylococcus aureus
Length = 579
Score = 61.7 bits (143), Expect = 1e-08
Identities = 34/113 (30%), Positives = 60/113 (53%), Gaps = 2/113 (1%)
Frame = +2
Query: 221 IDGNTILAESLKKQGVEYVFGIVG--IPVIETAMAFQSAGLKYIGMRNEQAACYAAQATG 394
I N L ++L+ +++++GI G I + ++ K+ +R+E+ A AA
Sbjct: 4 IKANEALVKALQAWDIDHLYGIPGDSIDAVVDSLRTVRDQFKFYHVRHEEVASLAAAGYT 63
Query: 395 YLTGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQE 553
LTGK GV L + GPGL+H + GM +A+++ P ++++G FQE
Sbjct: 64 KLTGKIGVALSIGGPGLIHLLNGMYDAKMDNVPQLILSGQTNSTALGTKAFQE 116
>UniRef50_Q3XZD0 Cluster: Pyruvate decarboxylase; n=3;
Lactobacillales|Rep: Pyruvate decarboxylase -
Enterococcus faecium DO
Length = 576
Score = 61.7 bits (143), Expect = 1e-08
Identities = 35/113 (30%), Positives = 55/113 (48%), Gaps = 2/113 (1%)
Frame = +2
Query: 221 IDGNTILAESLKKQGVEYVFGIVG--IPVIETAMAFQSAGLKYIGMRNEQAACYAAQATG 394
I+ + + L+ G+++++GI G I A+ + + YI +R+E+ AA A
Sbjct: 4 INAGIAMVKVLESWGIDHIYGIPGGSFNSIMDALYQEKTEINYIQVRHEEVGALAAAADA 63
Query: 395 YLTGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQE 553
LTGK G +GPG H I G+ +AQ++ PLV G FQE
Sbjct: 64 KLTGKVGAVFGSAGPGATHLINGLYDAQMDHVPLVAFLGQVASTSMNYNSFQE 116
>UniRef50_Q13G09 Cluster: Putative pyruvate decarboxylase; n=2;
Burkholderia xenovorans LB400|Rep: Putative pyruvate
decarboxylase - Burkholderia xenovorans (strain LB400)
Length = 587
Score = 61.7 bits (143), Expect = 1e-08
Identities = 41/118 (34%), Positives = 59/118 (50%), Gaps = 2/118 (1%)
Frame = +2
Query: 221 IDGNTILAESLKKQGVEYVFGIVGIPVIET--AMAFQSAGLKYIGMRNEQAACYAAQATG 394
+ G I+AE L GV V I G ++E A+A + + R+E YAAQA G
Sbjct: 30 VSGARIVAEVLGAYGVPAVTFIPGEGILEIVDALAVHTPQIALASFRHEAGMAYAAQAIG 89
Query: 395 YLTGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQVD 568
L+G+PGVCL PG L+ + A + P+V+I G + +AI G + VD
Sbjct: 90 QLSGQPGVCLAARAPGALNTTLAVHTAFTDSAPMVLIVG---QASQAISGREAMLNVD 144
>UniRef50_A4SWA9 Cluster: Thiamine pyrophosphate enzyme domain
protein TPP-binding; n=7; Proteobacteria|Rep: Thiamine
pyrophosphate enzyme domain protein TPP-binding -
Polynucleobacter sp. QLW-P1DMWA-1
Length = 576
Score = 61.7 bits (143), Expect = 1e-08
Identities = 30/91 (32%), Positives = 51/91 (56%)
Frame = +2
Query: 236 ILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTGKPG 415
++ E + GV++ +G++G + + A + +++I +R+E+ +AA A YLTG
Sbjct: 8 VIVEVFESAGVKHFYGVIGDTLNYVSDAISKSSIEWIHVRHEEVGAFAAGADSYLTGTLA 67
Query: 416 VCLVVSGPGLLHCIGGMANAQVNCWPLVVIA 508
C GPG LH I G+ A + PL+VIA
Sbjct: 68 GCAGSCGPGSLHLINGVYEAHRSRIPLLVIA 98
>UniRef50_Q97UP3 Cluster: Acetolactate synthase large subunit
homolog; n=6; Archaea|Rep: Acetolactate synthase large
subunit homolog - Sulfolobus solfataricus
Length = 552
Score = 61.7 bits (143), Expect = 1e-08
Identities = 33/107 (30%), Positives = 57/107 (53%), Gaps = 1/107 (0%)
Frame = +2
Query: 236 ILAESLKKQGVEYVFGIVGIPVIETAMAFQ-SAGLKYIGMRNEQAACYAAQATGYLTGKP 412
I+ E+L K G++ ++GI G + A + + +KYI +R+E+ A +AA LT
Sbjct: 8 IIVEALVKAGIKRIYGIPGDSIDPLMDAIRRNKEIKYIQVRHEEGAAFAASVESKLTSNV 67
Query: 413 GVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQE 553
C+ SGPG +H + G+ +A+++ +V + G D FQE
Sbjct: 68 TACMGTSGPGSIHLLNGLYDAKMDHASVVALTGQIESDMIGHDYFQE 114
>UniRef50_Q9RU76 Cluster: Acetolactate synthase; n=3; Bacteria|Rep:
Acetolactate synthase - Deinococcus radiodurans
Length = 592
Score = 61.3 bits (142), Expect = 2e-08
Identities = 38/112 (33%), Positives = 60/112 (53%), Gaps = 3/112 (2%)
Frame = +2
Query: 227 GNTILAESLKKQGVEYVFGIVG---IPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGY 397
G L +L G+ VFG G +PV + A+ F +++I R+EQ A +AA+
Sbjct: 16 GAKALWATLAGHGITTVFGYPGGAIMPVYD-ALTFYPE-VRHILARHEQGAIHAAEGWAK 73
Query: 398 LTGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQE 553
TG+ GVC+ SGPG + + G+A+A ++ PL+ I G+ + FQE
Sbjct: 74 ATGEIGVCMATSGPGATNLVTGLADAMLDSVPLLAITGNVAQHLMGTDAFQE 125
>UniRef50_Q88YC4 Cluster: Pyruvate oxidase; n=5;
Lactobacillales|Rep: Pyruvate oxidase - Lactobacillus
plantarum
Length = 587
Score = 61.3 bits (142), Expect = 2e-08
Identities = 33/107 (30%), Positives = 56/107 (52%), Gaps = 2/107 (1%)
Frame = +2
Query: 239 LAESLKKQGVEYVFGIVGIPVIETA--MAFQSAGLKYIGMRNEQAACYAAQATGYLTGKP 412
L + L+ GV++++GI G + T + + A + YI +R+E+ AA A TGK
Sbjct: 11 LVKVLEAWGVDHIYGIPGGSINHTVEGLYLEKADIDYIQVRHEEVGALAASADAKFTGKI 70
Query: 413 GVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQE 553
GV +GPG H G+ +A+++ P++ + G P+ FQE
Sbjct: 71 GVSFGSAGPGATHLFNGLYDAKMDHVPVLALVGQVPQATMNTNYFQE 117
>UniRef50_Q2LXP1 Cluster: Acetolactate synthase large subunit; n=1;
Syntrophus aciditrophicus SB|Rep: Acetolactate synthase
large subunit - Syntrophus aciditrophicus (strain SB)
Length = 557
Score = 61.3 bits (142), Expect = 2e-08
Identities = 36/111 (32%), Positives = 60/111 (54%), Gaps = 2/111 (1%)
Frame = +2
Query: 227 GNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTG 406
G I+ + L+++GVE +FG G + + +++ R+EQAA +AA TG
Sbjct: 5 GADIVLQILQEEGVEAIFGYPGGNSLPLHDRLLGSPIRHYLTRHEQAAAHAADGYARATG 64
Query: 407 KPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIG--GFQE 553
+ GVCL SGPG + + G+A A ++ P+V + +C + +G FQE
Sbjct: 65 RVGVCLSTSGPGATNLVTGIATAHMDSSPIVAL--TCQVNTSLMGRDAFQE 113
>UniRef50_Q1ATS7 Cluster: Thiamine pyrophosphate enzyme-like TPP
binding region; n=2; Actinobacteria (class)|Rep:
Thiamine pyrophosphate enzyme-like TPP binding region -
Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 547
Score = 61.3 bits (142), Expect = 2e-08
Identities = 32/96 (33%), Positives = 46/96 (47%)
Frame = +2
Query: 239 LAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTGKPGV 418
+ + L +GVE FG+VG A Q AG K+ R+E A A +GK GV
Sbjct: 7 IGQVLADRGVEVFFGLVGSGNFTVVDALQKAGAKFYSARHECGAVMMADGYARASGKVGV 66
Query: 419 CLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPED 526
C GPG + + G+ A N PL+++A P +
Sbjct: 67 CSTHQGPGFTNALTGLTEAAKNRTPLLLLAADTPPE 102
>UniRef50_A3PYZ1 Cluster: Thiamine pyrophosphate enzyme TPP binding
domain protein; n=3; Mycobacterium|Rep: Thiamine
pyrophosphate enzyme TPP binding domain protein -
Mycobacterium sp. (strain JLS)
Length = 588
Score = 61.3 bits (142), Expect = 2e-08
Identities = 45/142 (31%), Positives = 67/142 (47%), Gaps = 4/142 (2%)
Frame = +2
Query: 188 CVSQKLNGSMGIDGNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQA 367
CV M + G +LA +L GV VF + G + +A ++ R+E +
Sbjct: 10 CVVGAWRWHMTVSGGDLLARALADAGVTEVFTLHGGHLDAFLVACGKHDVRLTDTRHESS 69
Query: 368 ACYAAQATGYLTGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCP----EDHEA 535
A +AA A +TG GVC+V SGPG + +ANA ++ P + I G P E +
Sbjct: 70 AGHAADAYARVTGSLGVCVVTSGPGFTNAYTAIANAYLDRTPTLFIVGGPPLRESETNPL 129
Query: 536 IGGFQEWPQVDSSRMYCKYAAR 601
GGF QV ++ K+A R
Sbjct: 130 QGGFD---QVAAAAPVTKWAYR 148
>UniRef50_A2U4W9 Cluster: Thiamine pyrophosphate enzyme-like
TPP-binding; n=4; Bacteria|Rep: Thiamine pyrophosphate
enzyme-like TPP-binding - Bacillus coagulans 36D1
Length = 574
Score = 61.3 bits (142), Expect = 2e-08
Identities = 34/107 (31%), Positives = 57/107 (53%), Gaps = 1/107 (0%)
Frame = +2
Query: 236 ILAESLKKQGVEYVFGIVGIPVIETAMAFQSAG-LKYIGMRNEQAACYAAQATGYLTGKP 412
+L +SL GV+ ++GIVG + + + +G ++++G+R+E+ A +AA A L
Sbjct: 8 LLIDSLLNAGVKRIYGIVGDSLNAVLDSIRRSGRIEWVGVRHEEVAAFAAGAEATLNNSI 67
Query: 413 GVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQE 553
VC SGPG LH I G+ + + P++ IA P FQ+
Sbjct: 68 AVCAGSSGPGNLHLINGLYDCNRSRVPVLAIAAHIPSSEIGSEYFQQ 114
>UniRef50_P42463 Cluster: Acetolactate synthase large subunit; n=69;
cellular organisms|Rep: Acetolactate synthase large
subunit - Corynebacterium glutamicum (Brevibacterium
flavum)
Length = 626
Score = 61.3 bits (142), Expect = 2e-08
Identities = 34/110 (30%), Positives = 57/110 (51%), Gaps = 1/110 (0%)
Frame = +2
Query: 227 GNTILAESLKKQGVEYVFGIVGIPVIETA-MAFQSAGLKYIGMRNEQAACYAAQATGYLT 403
G + SL++ + VFGI G V+ + S ++++ +R+EQ A +AA +T
Sbjct: 28 GAKAIVRSLEELNADIVFGIPGGAVLPVYDPLYSSTKVRHVLVRHEQGAGHAATGYAQVT 87
Query: 404 GKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQE 553
G+ GVC+ SGPG + + +A+A ++ P+V I G FQE
Sbjct: 88 GRVGVCIATSGPGATNLVTPIADANLDSVPMVAITGQVGSGLLGTDAFQE 137
>UniRef50_Q6F7C0 Cluster: Pyruvate dehydrogenase; n=7;
Proteobacteria|Rep: Pyruvate dehydrogenase -
Acinetobacter sp. (strain ADP1)
Length = 573
Score = 60.9 bits (141), Expect = 2e-08
Identities = 36/119 (30%), Positives = 62/119 (52%), Gaps = 1/119 (0%)
Frame = +2
Query: 236 ILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTGKPG 415
I+ E L++ GV+ +GIVG + + + +++I +R+E+ +AA L+G
Sbjct: 9 IIIEVLEQAGVQRCYGIVGDTLNHVTDSMSKSKIEWIHVRHEEVGGFAAGTDALLSGHLT 68
Query: 416 VCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQ-VDSSRMYCK 589
C GPG LH I G+ + N P+++IA + + GF ++PQ VD +Y K
Sbjct: 69 ACAGSCGPGSLHFINGLYESHRNRAPVILIASQISTE---MAGFIDFPQYVDFKSVYAK 124
>UniRef50_A5W0I1 Cluster: Thiamine pyrophosphate enzyme TPP binding
domain protein; n=1; Pseudomonas putida F1|Rep: Thiamine
pyrophosphate enzyme TPP binding domain protein -
Pseudomonas putida F1
Length = 610
Score = 60.9 bits (141), Expect = 2e-08
Identities = 40/129 (31%), Positives = 65/129 (50%), Gaps = 10/129 (7%)
Frame = +2
Query: 239 LAESLKKQGVEYVFGIVGIPVIETAMAFQS-AGLKYIGMRNEQAACYAAQATGYLTGKPG 415
+A+ L +QGVE VF + G + A L+ M +EQA AA+ +TGKP
Sbjct: 9 IAQWLVQQGVEQVFTVTGGGAMFLNQALGGHEQLRCTFMHHEQACAMAAEGYARITGKPA 68
Query: 416 VCLVVSGPGLLHCIGGMANAQVNCWPLVVIAG-----SCPEDHEAIG----GFQEWPQVD 568
V ++ +GPG ++ + G+ A + P++V++G +C + G G QE P +
Sbjct: 69 VVMLTTGPGSINALNGVHGAFTDSIPMIVLSGQIKRETCVSFQDVPGLRQLGDQEGPTIA 128
Query: 569 SSRMYCKYA 595
+ CKYA
Sbjct: 129 MASPVCKYA 137
>UniRef50_Q7RCT1 Cluster: Peroxisomal-coenzyme a synthetase; n=5;
Plasmodium (Vinckeia)|Rep: Peroxisomal-coenzyme a
synthetase - Plasmodium yoelii yoelii
Length = 1377
Score = 60.5 bits (140), Expect = 3e-08
Identities = 36/118 (30%), Positives = 60/118 (50%), Gaps = 9/118 (7%)
Frame = +2
Query: 236 ILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTGKP- 412
I+A LKK +++++G+ GIP+ + + + YI RNE A + Y + K
Sbjct: 648 IIAIILKKYKIDHIYGVYGIPINKIIKSLIKNKIYYISFRNEINAAISCNYVNYFSTKKQ 707
Query: 413 ---GVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDH-----EAIGGFQEWPQ 562
G+ V SGPG ++ I G+ N+++N P+V+I D+ E FQ +PQ
Sbjct: 708 KKVGIIFVCSGPGFINTISGLYNSKINNLPMVLICFENYIDNNLTLFEKYNNFQYFPQ 765
>UniRef50_A1ULA9 Cluster: Thiamine pyrophosphate enzyme TPP binding
domain protein; n=5; Actinomycetales|Rep: Thiamine
pyrophosphate enzyme TPP binding domain protein -
Mycobacterium sp. (strain KMS)
Length = 574
Score = 60.1 bits (139), Expect = 4e-08
Identities = 34/106 (32%), Positives = 52/106 (49%), Gaps = 1/106 (0%)
Frame = +2
Query: 239 LAESLKKQGVEYVFGIVGIPVIETAMAFQSAGL-KYIGMRNEQAACYAAQATGYLTGKPG 415
L L+ G + VFG G V A Q +G ++I R+E+ A + A TG+ G
Sbjct: 9 LVARLRDWGADRVFGYAGDGVNTLLGALQRSGAPEFISTRHEELAAFMACGHAKYTGRVG 68
Query: 416 VCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQE 553
VC+ GPG +H + G+ +A+++ P+V I G G QE
Sbjct: 69 VCMATQGPGAIHLLAGLYDAKLDKRPVVAIVGQVVSTALGSGYLQE 114
>UniRef50_A0K0V5 Cluster: Thiamine pyrophosphate enzyme domain
protein TPP-binding; n=1; Arthrobacter sp. FB24|Rep:
Thiamine pyrophosphate enzyme domain protein TPP-binding
- Arthrobacter sp. (strain FB24)
Length = 583
Score = 60.1 bits (139), Expect = 4e-08
Identities = 30/107 (28%), Positives = 52/107 (48%)
Frame = +2
Query: 236 ILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTGKPG 415
++ +SL GVE + + G ++ +G+ + R+E A Y A+A G + +PG
Sbjct: 48 VIVDSLAMHGVERTYVVPGESFLDVLDGLHGSGIDTVVCRHEGGAAYMAEADGKMNQRPG 107
Query: 416 VCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEW 556
V +V GPG + G+ A + P+++ G P H FQE+
Sbjct: 108 VAMVTRGPGAANAHVGLHTAWQDSTPMLLFVGLIPFAHRDREAFQEF 154
>UniRef50_A0IIS8 Cluster: Thiamine pyrophosphate enzyme-like
TPP-binding; n=2; Proteobacteria|Rep: Thiamine
pyrophosphate enzyme-like TPP-binding - Serratia
proteamaculans 568
Length = 609
Score = 60.1 bits (139), Expect = 4e-08
Identities = 31/106 (29%), Positives = 57/106 (53%)
Frame = +2
Query: 236 ILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTGKPG 415
++ + L+ +G++++F + G V + + + + I +E A + A + K G
Sbjct: 38 VIIQGLEARGIQHIFLVPGKLVYPLIKSIEHSAISGIVGAHETACGFMADGYARASRKFG 97
Query: 416 VCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQE 553
VCL +SGPG ++ + MA AQ + P++ +AG HEA G FQ+
Sbjct: 98 VCLGISGPGTMNFLPAMAAAQADKIPVLYLAGGIATYHEAQGAFQD 143
>UniRef50_Q7NTF5 Cluster: Benzoylformate decarboxylase; n=2;
cellular organisms|Rep: Benzoylformate decarboxylase -
Chromobacterium violaceum
Length = 638
Score = 59.7 bits (138), Expect = 6e-08
Identities = 40/120 (33%), Positives = 63/120 (52%), Gaps = 5/120 (4%)
Frame = +2
Query: 251 LKKQGVEYVFGIVG---IPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTGKPGVC 421
L + G+ +FG+ G IP+I+ ++ ++YI +E A AA + +TGKPGV
Sbjct: 21 LSQLGIHRIFGVPGTNEIPIID-GTSYPENQVEYIECLHENIAIGAAMGSARMTGKPGVL 79
Query: 422 LVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAI--GGFQEWPQVDSSRMYCKYA 595
+V PG+ H IG + NA + PLVV+ C + +E + VD +R Y K+A
Sbjct: 80 VVHVTPGIAHAIGNLFNAWRSQAPLVVLC--CQQQNELVTQEPLLASNLVDLARQYTKWA 137
>UniRef50_O28264 Cluster: Acetolactate synthase, large subunit; n=1;
Archaeoglobus fulgidus|Rep: Acetolactate synthase, large
subunit - Archaeoglobus fulgidus
Length = 543
Score = 59.7 bits (138), Expect = 6e-08
Identities = 30/97 (30%), Positives = 54/97 (55%)
Frame = +2
Query: 221 IDGNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYL 400
+DG +A++L ++ ++ F + ++ ++ G++ I R+EQAA AA +
Sbjct: 1 MDGAEAVAKALLREKIDCAFSLPSGEILPVCEYLEAEGVRVIFTRHEQAAGNAADGYARV 60
Query: 401 TGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAG 511
T +PG C+V +GPGL + + +A A P+V IAG
Sbjct: 61 TRRPGFCIVPTGPGLANLMPALAQAYYASSPVVAIAG 97
>UniRef50_Q3JBM9 Cluster: Acetolactate synthase large subunit; n=1;
Nitrosococcus oceani ATCC 19707|Rep: Acetolactate
synthase large subunit - Nitrosococcus oceani (strain
ATCC 19707 / NCIMB 11848)
Length = 602
Score = 59.3 bits (137), Expect = 7e-08
Identities = 37/114 (32%), Positives = 55/114 (48%), Gaps = 4/114 (3%)
Frame = +2
Query: 224 DGNTILAESLKKQGVEYVFGIVG--IPVIETAMA--FQSAGLKYIGMRNEQAACYAAQAT 391
+ +L L + V+YVFG+ G I + A+A + G + + R+E A + A
Sbjct: 20 EAGDLLVAYLAQLSVDYVFGVPGGAIEPLYNALARSARKGGPRAVVARHETGAAFMADGY 79
Query: 392 GYLTGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQE 553
G TGK VC +GPG + I G+A+A N P++VI H G QE
Sbjct: 80 GRQTGKLAVCCATTGPGATNLITGVASAYENRIPMLVITAQTALSHFGRGALQE 133
>UniRef50_A6G7M7 Cluster: Acetolactate synthase large subunit; n=1;
Plesiocystis pacifica SIR-1|Rep: Acetolactate synthase
large subunit - Plesiocystis pacifica SIR-1
Length = 562
Score = 59.3 bits (137), Expect = 7e-08
Identities = 31/91 (34%), Positives = 51/91 (56%)
Frame = +2
Query: 239 LAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTGKPGV 418
+AE + + ++ VFGI G + A AG++ + ++E A YAA TG PGV
Sbjct: 13 IAEVMMRHRIDRVFGIPGGTISPVFDALYGAGIELVTCQHETMAVYAAAGYARATGCPGV 72
Query: 419 CLVVSGPGLLHCIGGMANAQVNCWPLVVIAG 511
V SGPG L+ + G+A A + P+++++G
Sbjct: 73 VAVTSGPGALNALTGLAAACRDELPVLILSG 103
>UniRef50_A3JLQ7 Cluster: Sulphoacetaldehyde acetyltransferase,
putative; n=1; Rhodobacterales bacterium HTCC2150|Rep:
Sulphoacetaldehyde acetyltransferase, putative -
Rhodobacterales bacterium HTCC2150
Length = 562
Score = 59.3 bits (137), Expect = 7e-08
Identities = 34/116 (29%), Positives = 57/116 (49%), Gaps = 2/116 (1%)
Frame = +2
Query: 221 IDGNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAG-LKYIGMRNEQAACYAAQATGY 397
+ G + E+LK + +VFG++G +E A A + +IG+ +E+ C+ A
Sbjct: 4 MSGGQVAVEALKAEKTSHVFGLIGSATMEMFDALYDAPEINFIGVHDERTGCHMADGFAR 63
Query: 398 LTGKPGVCLV-VSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQ 562
+G+ GV L +GPG + G+ A+ P+V I+G+ H FQE Q
Sbjct: 64 ASGRAGVFLAGQNGPGTTNLATGLGQAKAAFSPVVSISGALATSHLYRDAFQEVDQ 119
>UniRef50_Q2U8M9 Cluster: Thiamine pyrophosphate-requiring enzymes;
n=2; Trichocomaceae|Rep: Thiamine
pyrophosphate-requiring enzymes - Aspergillus oryzae
Length = 597
Score = 59.3 bits (137), Expect = 7e-08
Identities = 42/141 (29%), Positives = 72/141 (51%), Gaps = 4/141 (2%)
Frame = +2
Query: 203 LNGSMG-IDGNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYA 379
LN G ++G +LA++LK GVE FG+ G + +++ ++ I R+E A A
Sbjct: 6 LNDHNGELNGGDLLAQTLKHLGVEVAFGLHGGHLDAFLQGCEASQIRLIDTRHETVAVQA 65
Query: 380 AQATGYLTGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCP---EDHEAIGGFQ 550
A++ + K GVC + + G + I G+A A + P++ I S P ++ ++ G
Sbjct: 66 AESYAKFSKKIGVCFITANSGFSNGIPGLATALADRSPILCITSSPPTRDAENNSLQGII 125
Query: 551 EWPQVDSSRMYCKYAARPPSP 613
+ QV SR K+A R +P
Sbjct: 126 D--QVVVSRPLTKFAYRMTNP 144
>UniRef50_Q0CL07 Cluster: Predicted protein; n=1; Aspergillus
terreus NIH2624|Rep: Predicted protein - Aspergillus
terreus (strain NIH 2624)
Length = 194
Score = 59.3 bits (137), Expect = 7e-08
Identities = 40/120 (33%), Positives = 57/120 (47%), Gaps = 3/120 (2%)
Frame = +2
Query: 203 LNGSMGIDGNTILAESLKKQGVEYVFGIVG---IPVIETAMAFQSAGLKYIGMRNEQAAC 373
L G +G G IL L GVEY+FG G +P+ + + + + I +EQ A
Sbjct: 6 LEGLIGRRGGDILEHILSTWGVEYIFGYPGGAALPLFDGI--YGTDKFQSIPTHHEQGAG 63
Query: 374 YAAQATGYLTGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQE 553
+ A+ TGKPGV LV SGPG + M NA ++ P++ I + FQE
Sbjct: 64 HMAEEYSQATGKPGVVLVTSGPGTSNLATPMLNALLDGNPMISICWKVESTAQGTNVFQE 123
>UniRef50_Q5FHQ7 Cluster: Pyruvate oxidase; n=12;
Lactobacillaceae|Rep: Pyruvate oxidase - Lactobacillus
acidophilus
Length = 601
Score = 58.8 bits (136), Expect = 1e-07
Identities = 36/134 (26%), Positives = 69/134 (51%), Gaps = 6/134 (4%)
Frame = +2
Query: 221 IDGNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAG--LKYIGMRNEQAACYAAQATG 394
I+G+ + + + G+++++G G + A +K+I +R+E+A AA +
Sbjct: 4 INGSDAMLKVIYDWGIDHIYGFPGGSFDSSMNAIYDFRDKMKFIEVRHEEAGALAASSEY 63
Query: 395 YLTGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQ---- 562
+TGK GVC +GPG H G+ +A+ + P++ I + P + I FQ + +
Sbjct: 64 KVTGKLGVCFGSAGPGAAHLFNGLYDAKYDKTPMLAIVANVPTSKQDIDFFQAFDEDKWF 123
Query: 563 VDSSRMYCKYAARP 604
+D+S ++C A P
Sbjct: 124 LDAS-VWCASAKTP 136
>UniRef50_A6NPM8 Cluster: Acetolactate synthase; n=2; Bacteria|Rep:
Acetolactate synthase - Bacteroides capillosus ATCC
29799
Length = 568
Score = 58.8 bits (136), Expect = 1e-07
Identities = 39/110 (35%), Positives = 53/110 (48%), Gaps = 4/110 (3%)
Frame = +2
Query: 236 ILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLK----YIGMRNEQAACYAAQATGYLT 403
IL E L +QGV+ VFG G ++ + G K +I +EQ A +AA T
Sbjct: 8 ILMECLLEQGVDTVFGYPGGTILNVYDELELHGYKDKIRHILTAHEQGASHAADGYARAT 67
Query: 404 GKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQE 553
GK GVC SGPG + G+A A + P+V I + E+ FQE
Sbjct: 68 GKVGVCFATSGPGATNLTTGIATAYYDSSPVVFITVNVAENLIGKDSFQE 117
>UniRef50_A6E1Z9 Cluster: Acetolactate synthase II large subunit;
n=2; Roseovarius|Rep: Acetolactate synthase II large
subunit - Roseovarius sp. TM1035
Length = 571
Score = 58.8 bits (136), Expect = 1e-07
Identities = 35/112 (31%), Positives = 53/112 (47%), Gaps = 2/112 (1%)
Frame = +2
Query: 224 DGNTILAESLKKQGVEYVFGIVGIPVIETAMAFQ-SAG-LKYIGMRNEQAACYAAQATGY 397
+G +L + L G + FG+ G + A +AG L + R E A + A A G
Sbjct: 17 NGGQLLVDCLLALGARHSFGVPGESYLAVLDALHDTAGRLDFTLCRQEGGAAFMAAAYGK 76
Query: 398 LTGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQE 553
LTG+PG+C V GPG + G+ A + P+++ G D + FQE
Sbjct: 77 LTGRPGICWVTRGPGATNAAIGVHTAMQDSAPMILFVGQVGTDMKGREAFQE 128
>UniRef50_A4A3X6 Cluster: Acetolactate synthase isozyme I large
subunit; n=2; Gammaproteobacteria|Rep: Acetolactate
synthase isozyme I large subunit - Congregibacter
litoralis KT71
Length = 544
Score = 58.8 bits (136), Expect = 1e-07
Identities = 26/85 (30%), Positives = 47/85 (55%)
Frame = +2
Query: 251 LKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTGKPGVCLVV 430
L+ G++ VFGI G ++ ++ +++I R+EQ A + A +G+P C ++
Sbjct: 5 LEAYGIDTVFGIPGNHTVQLYRGLDNSSIRHISPRHEQGAAFMADGYARASGRPAACFLI 64
Query: 431 SGPGLLHCIGGMANAQVNCWPLVVI 505
SGPGL + I M A + P++V+
Sbjct: 65 SGPGLGNAITPMMQALADSVPMLVV 89
>UniRef50_A5UL13 Cluster: Acetolactate synthase (TPP-requiring),
large subunit, IlvB; n=1; Methanobrevibacter smithii
ATCC 35061|Rep: Acetolactate synthase (TPP-requiring),
large subunit, IlvB - Methanobrevibacter smithii (strain
PS / ATCC 35061 / DSM 861)
Length = 512
Score = 58.8 bits (136), Expect = 1e-07
Identities = 33/107 (30%), Positives = 57/107 (53%)
Frame = +2
Query: 239 LAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTGKPGV 418
L + L+++G+E +FG+ G ++ A + + + +I +R+EQAA +AA A + K
Sbjct: 7 LVKILEEEGLENIFGLPGEQILPFYKALKDSKINHILVRHEQAAMHAADAYYKSSHKLSA 66
Query: 419 CLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWP 559
C+ + PG L+ +A A + PL+V+ G P D FQ P
Sbjct: 67 CVATAAPGALNFTMALAGAYKDNVPLLVLTGDNPTDLRNEDVFQSLP 113
>UniRef50_Q89F88 Cluster: Acetolactate synthase large subunit; n=12;
Proteobacteria|Rep: Acetolactate synthase large subunit
- Bradyrhizobium japonicum
Length = 553
Score = 58.4 bits (135), Expect = 1e-07
Identities = 35/109 (32%), Positives = 49/109 (44%)
Frame = +2
Query: 227 GNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTG 406
G IL + L QGVE V + G + A + + + R E A A+A G LTG
Sbjct: 9 GGQILIDQLVAQGVERVTCVPGESYLAALDALHDSPIDVMICRAEGGAAMMAEAYGKLTG 68
Query: 407 KPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQE 553
+PGVC V GPG + G+ A + P+++ G FQE
Sbjct: 69 RPGVCFVTRGPGATNASHGVHIAMQDSTPMILFVGQVDTGMREREAFQE 117
>UniRef50_Q1GFA1 Cluster: Thiamine pyrophosphate enzyme-like
TPP-binding; n=57; Proteobacteria|Rep: Thiamine
pyrophosphate enzyme-like TPP-binding - Silicibacter sp.
(strain TM1040)
Length = 570
Score = 58.4 bits (135), Expect = 1e-07
Identities = 35/125 (28%), Positives = 59/125 (47%), Gaps = 2/125 (1%)
Frame = +2
Query: 227 GNTILAESLKKQGVEYVFGIVGIPVIET--AMAFQSAGLKYIGMRNEQAACYAAQATGYL 400
G +LA+ L+ G + ++ + G +E + + + R+E A A A G L
Sbjct: 16 GGRVLADQLQILGADTIYCVPGESYLELLDGLHAHQESINVVTCRHESGASNMADAYGKL 75
Query: 401 TGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQVDSSRM 580
TGKPG+C V GPG + G+ A + P++++ G + FQE +D RM
Sbjct: 76 TGKPGICAVTRGPGATNASNGVHTAFQDSTPMILLIGQVGREMVDREAFQE---IDYRRM 132
Query: 581 YCKYA 595
+ + A
Sbjct: 133 FGQMA 137
>UniRef50_Q6JHM8 Cluster: Acetolactate synthase; n=1;
Saccharopolyspora spinosa|Rep: Acetolactate synthase -
Saccharopolyspora spinosa
Length = 533
Score = 58.0 bits (134), Expect = 2e-07
Identities = 31/90 (34%), Positives = 50/90 (55%), Gaps = 1/90 (1%)
Frame = +2
Query: 239 LAESLKKQGVEYVFGIVGIPV-IETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTGKPG 415
+AE++ G + VFG+ G ++ A ++ GL+++ E A A G LT PG
Sbjct: 10 IAEAVAAAGADTVFGMPGGGNNLDFIGAAEAIGLRFVLAHAETPAAMMASVYGDLTDSPG 69
Query: 416 VCLVVSGPGLLHCIGGMANAQVNCWPLVVI 505
VC+V GPG + G+ANA ++ PLV++
Sbjct: 70 VCVVTRGPGAASAVNGVANAMLDRQPLVLV 99
>UniRef50_A5WFU5 Cluster: Pyruvate oxidase; n=1; Psychrobacter sp.
PRwf-1|Rep: Pyruvate oxidase - Psychrobacter sp. PRwf-1
Length = 603
Score = 58.0 bits (134), Expect = 2e-07
Identities = 35/106 (33%), Positives = 54/106 (50%), Gaps = 2/106 (1%)
Frame = +2
Query: 251 LKKQGVEYVFGIVGIPVIETAMAFQS--AGLKYIGMRNEQAACYAAQATGYLTGKPGVCL 424
L GV+ ++G+ G + T A + +KYIG+R+E+ AA A TGK V L
Sbjct: 14 LNDWGVKRIYGLPGGSLDSTMNAIYNWRDKIKYIGVRHEEVGGLAAVAEAKWTGKIAVML 73
Query: 425 VVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQ 562
+GPG H + + +A ++ P++ I G P D FQE P+
Sbjct: 74 GSAGPGAAHLLNPLHDAALDHIPVLAIVGQVPSDKMNTDYFQEMPE 119
>UniRef50_A3VG64 Cluster: Acetolactate synthase large subunit; n=1;
Rhodobacterales bacterium HTCC2654|Rep: Acetolactate
synthase large subunit - Rhodobacterales bacterium
HTCC2654
Length = 539
Score = 58.0 bits (134), Expect = 2e-07
Identities = 37/114 (32%), Positives = 51/114 (44%), Gaps = 2/114 (1%)
Frame = +2
Query: 239 LAESLKKQGVEYVFGIVGIPVIETAMAFQSA-GLKYIGMRNEQAACYAAQATGYLTGKPG 415
LA SL GV ++FG+VG A+ G Y+ NE A A LTG G
Sbjct: 9 LARSLAAHGVTHLFGVVGDANAYFVDAYARLDGTHYVTAANENGAVLMAIGAAMLTGDVG 68
Query: 416 VCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCP-EDHEAIGGFQEWPQVDSS 574
C V GP L +C+ +A + P+V++ G P D E + + V SS
Sbjct: 69 FCTVTHGPALTNCVTALAEGARSNTPIVLLCGDTPVHDRENLQNIDQKAVVLSS 122
>UniRef50_A5K231 Cluster: Bi-functional enzyme: long-chain
fatty-acid Co-A ligase and oxalyl Co- A decarboxylase,
putative; n=1; Plasmodium vivax|Rep: Bi-functional
enzyme: long-chain fatty-acid Co-A ligase and oxalyl Co-
A decarboxylase, putative - Plasmodium vivax
Length = 1314
Score = 58.0 bits (134), Expect = 2e-07
Identities = 33/96 (34%), Positives = 52/96 (54%), Gaps = 6/96 (6%)
Frame = +2
Query: 236 ILAESLKKQGVE-YVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYL---- 400
+LA LKK ++ Y++G+ GIP+ + +F + YI RNE AC + Y
Sbjct: 628 VLALCLKKAHLDDYLYGVYGIPLNKVLPSFVGNQVHYISFRNEINACLSGSYVNYFDQQR 687
Query: 401 -TGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVI 505
K G+ L SGP ++ + G+ NA+VN +PL+ I
Sbjct: 688 GKKKVGMILTCSGPAFVNALPGLYNAKVNHFPLIFI 723
>UniRef50_Q5WGG1 Cluster: Acetolactate synthase large subunit; n=1;
Bacillus clausii KSM-K16|Rep: Acetolactate synthase
large subunit - Bacillus clausii (strain KSM-K16)
Length = 544
Score = 57.6 bits (133), Expect = 2e-07
Identities = 30/96 (31%), Positives = 52/96 (54%)
Frame = +2
Query: 233 TILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTGKP 412
+++ + +K++G + VFG+ G PV+ +A + +G+ ++ R+E A + A TG
Sbjct: 6 SMIVKFIKEKGCKTVFGVPGKPVVPLILAMEESGVSFVLARHEGGAGFMATGYALQTGGL 65
Query: 413 GVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCP 520
GV + SGPG + I A AQ P++ I G P
Sbjct: 66 GVAIGTSGPGGTNMITAAAQAQAFHAPVLFITGHPP 101
>UniRef50_Q5LPG3 Cluster: Acetolactate synthase, catabolic,
putative; n=7; Bacteria|Rep: Acetolactate synthase,
catabolic, putative - Silicibacter pomeroyi
Length = 539
Score = 57.6 bits (133), Expect = 2e-07
Identities = 31/101 (30%), Positives = 54/101 (53%)
Frame = +2
Query: 236 ILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTGKPG 415
+LA L + G + FG+ G V+ A AG+ + ++E AA + A+A + G P
Sbjct: 11 LLARRLYEAGCRHAFGMPGGEVLTLVDALDKAGITFHLAKHENAAGFMAEAVHHRDGAPA 70
Query: 416 VCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAI 538
+ L GPG ++ + +ANA + P++V+ G C + EA+
Sbjct: 71 ILLATLGPGAMNGVNVVANALQDRVPMIVLTG-CVDADEAL 110
>UniRef50_A0JT80 Cluster: Thiamine pyrophosphate enzyme TPP binding
domain protein; n=7; Actinobacteria (class)|Rep:
Thiamine pyrophosphate enzyme TPP binding domain protein
- Arthrobacter sp. (strain FB24)
Length = 552
Score = 57.6 bits (133), Expect = 2e-07
Identities = 31/101 (30%), Positives = 49/101 (48%)
Frame = +2
Query: 224 DGNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLT 403
+G ++ E+L+ G + VFGI G + A L ++ R E + +AA T
Sbjct: 6 NGGDLVVETLEALGAKTVFGIPGQHALGLFDAMGRGNLHFVSSRVENNSAFAADGYSRAT 65
Query: 404 GKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPED 526
G+ GV + +GPG L + G+ A P+VV+A P D
Sbjct: 66 GEVGVLFLSTGPGALTSLAGLQEAYATGVPMVVVASQIPLD 106
>UniRef50_Q988P8 Cluster: Acetolactate synthase, large subunit; n=6;
Bacteria|Rep: Acetolactate synthase, large subunit -
Rhizobium loti (Mesorhizobium loti)
Length = 600
Score = 57.2 bits (132), Expect = 3e-07
Identities = 36/115 (31%), Positives = 55/115 (47%), Gaps = 2/115 (1%)
Frame = +2
Query: 215 MGIDGNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAG--LKYIGMRNEQAACYAAQA 388
M + G I+A +LK+ GVEYV G+ G + AF G L +I + +EQ+A + A
Sbjct: 1 MKLTGGQIVARALKEYGVEYVAGVPGHGIWSLFDAFLEEGSTLPFIQVMHEQSAVHMADG 60
Query: 389 TGYLTGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQE 553
+G+P C GPG + I G+A + P ++G + G QE
Sbjct: 61 FFRASGRPMACSTSIGPGATNTIIGLATCYADSIPAFFVSGGPATHMKGHGVMQE 115
>UniRef50_Q88S56 Cluster: Pyruvate oxidase; n=2; Lactobacillus
plantarum|Rep: Pyruvate oxidase - Lactobacillus
plantarum
Length = 584
Score = 57.2 bits (132), Expect = 3e-07
Identities = 34/116 (29%), Positives = 56/116 (48%), Gaps = 2/116 (1%)
Frame = +2
Query: 221 IDGNTILAESLKKQGVEYVFGIVGIPVIETAMAF--QSAGLKYIGMRNEQAACYAAQATG 394
I LA+ L +++++GI + T F + LKYI +R+E+ AA A
Sbjct: 6 IKAGQALAQVLVDWNIDHIYGITADSINNTVDGFYQEKDHLKYIQVRHEEVGALAAAADA 65
Query: 395 YLTGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQ 562
LTG GV +GPG +H + G+ +A+++ P++ + G FQE Q
Sbjct: 66 KLTGTIGVSFGSAGPGAVHLLNGLYDAKMDHVPVLALVGQSATSIMNTNFFQEMNQ 121
>UniRef50_P37063 Cluster: Pyruvate oxidase; n=2; Lactobacillus
plantarum|Rep: Pyruvate oxidase - Lactobacillus
plantarum
Length = 603
Score = 57.2 bits (132), Expect = 3e-07
Identities = 34/103 (33%), Positives = 56/103 (54%), Gaps = 2/103 (1%)
Frame = +2
Query: 251 LKKQGVEYVFGIVG--IPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTGKPGVCL 424
L+ GV++++GI G I I A++ + + YI +R+E+ AA A LTGK GVC
Sbjct: 21 LEAWGVDHLYGIPGGSINSIMDALSAERDRIHYIQVRHEEVGAMAAAADAKLTGKIGVCF 80
Query: 425 VVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQE 553
+GPG H + G+ +A+ + P++ + G + FQE
Sbjct: 81 GSAGPGGTHLMNGLYDAREDHVPVLALIGQFGTTGMNMDTFQE 123
>UniRef50_Q8KTR7 Cluster: Valine sensitive acetolactate synthase III
subunit; n=1; Candidatus Tremblaya princeps|Rep: Valine
sensitive acetolactate synthase III subunit - Tremblaya
princeps
Length = 565
Score = 56.8 bits (131), Expect = 4e-07
Identities = 34/103 (33%), Positives = 55/103 (53%), Gaps = 1/103 (0%)
Frame = +2
Query: 248 SLKKQGVEYVFGIVGIPVIETAMAFQSAGL-KYIGMRNEQAACYAAQATGYLTGKPGVCL 424
+L + + ++G G V+ GL +++ +R+E AA YAA + T + G CL
Sbjct: 13 TLSRMAILRLWGYPGGSVLGLYDEIYRCGLLRHMSVRSEPAAAYAACSFYAATRELGSCL 72
Query: 425 VVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQE 553
V SGPG+ + I G+A A + ++VI+G P +G FQE
Sbjct: 73 VTSGPGITNAITGIATADADSVAVLVISGQVPLASIGMGSFQE 115
>UniRef50_A4IL27 Cluster: Acetolactate synthase; n=1; Geobacillus
thermodenitrificans NG80-2|Rep: Acetolactate synthase -
Geobacillus thermodenitrificans (strain NG80-2)
Length = 557
Score = 56.8 bits (131), Expect = 4e-07
Identities = 36/103 (34%), Positives = 54/103 (52%), Gaps = 2/103 (1%)
Frame = +2
Query: 227 GNTILAESLKKQGVEYVFGIVGIPVIETAMAFQS-AGLKYIGMRNEQAACYAAQATGYLT 403
G +L ESL QG+ ++FG ++ GL YI M++EQAA +AA +
Sbjct: 9 GADVLVESLAVQGIAHMFGCCHESMLPVRHVLNHHPGLSYIEMKHEQAAVHAADGYARAS 68
Query: 404 GKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAG-SCPEDH 529
GK GV ++ G G+ + I G+ A + PL+ I G PE+H
Sbjct: 69 GKLGVAII--GAGVTNGITGITTALSDSIPLLAIIGRPSPEEH 109
>UniRef50_A3T0A3 Cluster: Acetolactate synthase II large subunit;
n=3; Alphaproteobacteria|Rep: Acetolactate synthase II
large subunit - Sulfitobacter sp. NAS-14.1
Length = 561
Score = 56.8 bits (131), Expect = 4e-07
Identities = 32/111 (28%), Positives = 50/111 (45%), Gaps = 2/111 (1%)
Frame = +2
Query: 227 GNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKY--IGMRNEQAACYAAQATGYL 400
G +L + L G + + + G +E A ++ I R+E A A+ G L
Sbjct: 12 GGQVLVDQLLIHGADTAYCVPGESYLEVLDALHDVQDRFTLINARHEAGAANMAETYGKL 71
Query: 401 TGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQE 553
G PG+C+V GPG H G+ AQ + P++++ G D FQE
Sbjct: 72 HGTPGICMVTRGPGACHAAIGVHIAQQDSTPMILLVGQIARDTTDREAFQE 122
>UniRef50_A5US79 Cluster: Thiamine pyrophosphate enzyme, central
region precursor; n=3; Chloroflexaceae|Rep: Thiamine
pyrophosphate enzyme, central region precursor -
Roseiflexus sp. RS-1
Length = 847
Score = 56.4 bits (130), Expect = 5e-07
Identities = 35/124 (28%), Positives = 58/124 (46%)
Frame = +2
Query: 221 IDGNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYL 400
+DG ++ +L++ GV + F IVG + A + G++ I +RNE A + A A
Sbjct: 295 VDGGRLVVRTLREAGVTHAFTIVGGHNYQLVNACREEGIRVIDVRNEMHAAHMADAFARF 354
Query: 401 TGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQVDSSRM 580
T +P + V + PGL++ I G+ A PL++ IG Q Q+ R
Sbjct: 355 TRRPALLTVDAAPGLVNAIAGIEVAYEAQVPLIIACAQGSLAGRDIGVMQAIDQLRLLRP 414
Query: 581 YCKY 592
K+
Sbjct: 415 VTKW 418
>UniRef50_A1G7C7 Cluster: Thiamine pyrophosphate enzyme-like
TPP-binding; n=1; Salinispora arenicola CNS205|Rep:
Thiamine pyrophosphate enzyme-like TPP-binding -
Salinispora arenicola CNS205
Length = 565
Score = 56.0 bits (129), Expect = 7e-07
Identities = 34/108 (31%), Positives = 53/108 (49%), Gaps = 1/108 (0%)
Frame = +2
Query: 233 TILAESLKKQGVEYVFGIVGIPVIETAMA-FQSAGLKYIGMRNEQAACYAAQATGYLTGK 409
T L +L V+ VF + G + A + + ++ + R+E +A +AA A LTG+
Sbjct: 17 TTLVAALLGHDVDRVFCVAGESYLAVLDALYDTPTVEVVTCRHEASAAFAAVADAKLTGR 76
Query: 410 PGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQE 553
GVCLV GPG + + +A + PLV++ G P FQE
Sbjct: 77 AGVCLVSRGPGATNAGIAVHSAAQDATPLVLLVGHVPRSEIGTDAFQE 124
>UniRef50_O28180 Cluster: Acetolactate synthase, large subunit; n=1;
Archaeoglobus fulgidus|Rep: Acetolactate synthase, large
subunit - Archaeoglobus fulgidus
Length = 575
Score = 56.0 bits (129), Expect = 7e-07
Identities = 32/99 (32%), Positives = 52/99 (52%), Gaps = 4/99 (4%)
Frame = +2
Query: 221 IDGNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAG----LKYIGMRNEQAACYAAQA 388
I G +L L K+ V Y+FG+ G ++ A + G +K++ R+EQAA A A
Sbjct: 4 ISGGELLVRCLIKENVRYIFGVPGGQLLTFLDAIKRVGEKHGMKFVNCRHEQAAASMADA 63
Query: 389 TGYLTGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVI 505
++G+ GVC+ GPG + G+ A + P++VI
Sbjct: 64 YARVSGEIGVCVGTIGPGGADLVPGVYPAFADSVPMLVI 102
>UniRef50_UPI000050F80A Cluster: COG0028: Thiamine
pyrophosphate-requiring enzymes [acetolactate synthase,
pyruvate dehydrogenase (cytochrome), glyoxylate
carboligase, phosphonopyruvate decarboxylase]; n=1;
Brevibacterium linens BL2|Rep: COG0028: Thiamine
pyrophosphate-requiring enzymes [acetolactate synthase,
pyruvate dehydrogenase (cytochrome), glyoxylate
carboligase, phosphonopyruvate decarboxylase] -
Brevibacterium linens BL2
Length = 573
Score = 55.6 bits (128), Expect = 9e-07
Identities = 32/118 (27%), Positives = 53/118 (44%)
Frame = +2
Query: 203 LNGSMGIDGNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAA 382
++ S + +L + L+ GV+ + + G ++ + + I R E A Y A
Sbjct: 1 MDNSAPLSAGHLLVKELEAHGVQRSYLVPGESYLDVLDGLHDSTITPIVCRQEGGAGYMA 60
Query: 383 QATGYLTGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEW 556
A G +TG PG+ +V GPG + + + A + PLVV G P FQE+
Sbjct: 61 VAEGRMTGIPGIAMVTRGPGASNVMVSVHTAHQDATPLVVFVGLIPTAQRGRESFQEF 118
>UniRef50_Q6LF61 Cluster: Putative bi-functional enzyme: long-chain
fatty-acid Co-A ligase and oxalyl Co-A decarboxylase;
n=1; Plasmodium falciparum 3D7|Rep: Putative
bi-functional enzyme: long-chain fatty-acid Co-A ligase
and oxalyl Co-A decarboxylase - Plasmodium falciparum
(isolate 3D7)
Length = 1392
Score = 55.6 bits (128), Expect = 9e-07
Identities = 35/125 (28%), Positives = 58/125 (46%), Gaps = 12/125 (9%)
Frame = +2
Query: 230 NTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYL--- 400
+ I+ KK ++Y++G+ GIP+ + +F + YI RNE A + Y
Sbjct: 659 DNIIPLIFKKYDIKYIYGLYGIPINKIIYSFIKNNIYYISFRNEINASISCNYINYFDIN 718
Query: 401 ----TGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDH-----EAIGGFQE 553
K G+ SGP ++ + G+ NA+VN P+V+I + E FQ
Sbjct: 719 NKEEKNKIGILFTCSGPAFINTLSGLYNAKVNNLPMVLICFENVRNEKLTLFEKYCNFQY 778
Query: 554 WPQVD 568
+PQ+D
Sbjct: 779 FPQLD 783
>UniRef50_UPI000050FC62 Cluster: COG0028: Thiamine
pyrophosphate-requiring enzymes [acetolactate synthase,
pyruvate dehydrogenase (cytochrome), glyoxylate
carboligase, phosphonopyruvate decarboxylase]; n=1;
Brevibacterium linens BL2|Rep: COG0028: Thiamine
pyrophosphate-requiring enzymes [acetolactate synthase,
pyruvate dehydrogenase (cytochrome), glyoxylate
carboligase, phosphonopyruvate decarboxylase] -
Brevibacterium linens BL2
Length = 568
Score = 55.2 bits (127), Expect = 1e-06
Identities = 28/107 (26%), Positives = 52/107 (48%)
Frame = +2
Query: 221 IDGNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYL 400
I G LA +L+ +G+ V+GI G +E + G+ + R+EQ A Y A +
Sbjct: 8 ITGGAHLARALRAEGITRVYGIPGTHNLEIFAQLAAEGIDIVSPRHEQGAGYMADGAARV 67
Query: 401 TGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIG 541
TG+ V + +GP + + + + + + P+++I+ P H G
Sbjct: 68 TGEVQVVITTTGPAVFNALTALLQSFTDSVPVLLISPGMPLTHPGRG 114
>UniRef50_A1BBV8 Cluster: Thiamine pyrophosphate enzyme domain
protein TPP-binding; n=4; Proteobacteria|Rep: Thiamine
pyrophosphate enzyme domain protein TPP-binding -
Paracoccus denitrificans (strain Pd 1222)
Length = 567
Score = 55.2 bits (127), Expect = 1e-06
Identities = 32/97 (32%), Positives = 49/97 (50%), Gaps = 2/97 (2%)
Frame = +2
Query: 227 GNTILAESLKKQGVEYVFGIVG--IPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYL 400
G ILA+ L G V+ + G V A+A + ++ I R+E A A+A G L
Sbjct: 7 GAEILADELALNGARIVYHVPGESFLVALDALATRHPDIRAISCRHENGAAQMAEAHGKL 66
Query: 401 TGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAG 511
TG+PGV V PG + + G+ A + P+++I G
Sbjct: 67 TGQPGVAFVTRSPGATNAVNGVHTAFQDGSPMILIVG 103
>UniRef50_Q2GMZ7 Cluster: Putative uncharacterized protein; n=1;
Chaetomium globosum|Rep: Putative uncharacterized
protein - Chaetomium globosum (Soil fungus)
Length = 590
Score = 55.2 bits (127), Expect = 1e-06
Identities = 33/124 (26%), Positives = 63/124 (50%), Gaps = 5/124 (4%)
Frame = +2
Query: 239 LAESLKKQGVEYVFGIVGIPVIE--TAMAFQSAGLKYIGMRNEQAACYAAQATGYLTGKP 412
L + ++ G+ +FG+ G+ I ++ G++Y+ +E A AA + +TGKP
Sbjct: 33 LFDVCRELGITRIFGVPGVNEIPWIDGTSYPENGVEYVECLHENIAMGAAMGSARMTGKP 92
Query: 413 GVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQVDS---SRMY 583
+ +V PG+ H I + NA + +PL+++ C + A+ + D+ +R Y
Sbjct: 93 AILIVHVTPGIAHAITNLFNASRSQFPLIIL---CAQQQNALVVQEPLLSSDTVPLARNY 149
Query: 584 CKYA 595
CK+A
Sbjct: 150 CKWA 153
>UniRef50_Q3JVP4 Cluster: Pyruvate oxidase; n=17; Bacteria|Rep:
Pyruvate oxidase - Burkholderia pseudomallei (strain
1710b)
Length = 744
Score = 54.8 bits (126), Expect = 2e-06
Identities = 34/117 (29%), Positives = 62/117 (52%), Gaps = 2/117 (1%)
Frame = +2
Query: 239 LAESLKKQGVEYVFGIVGIPVIETAMAFQSAG--LKYIGMRNEQAACYAAQATGYLTGKP 412
+ E L GV ++G G + A A ++++ +R+E+ A + A A TG+
Sbjct: 144 IVERLYDWGVRRLYGYPGDGINGMFGALNRADGKIEFVQVRHEEMAAFMACAHAKFTGEL 203
Query: 413 GVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQVDSSRMY 583
GVC+ SGPG H + G+ +A+++ P++ IAG + A GG + ++D S ++
Sbjct: 204 GVCIATSGPGASHLVTGLYDARMDHMPVLAIAGQ--QARAARGGHYQ-QELDLSALF 257
>UniRef50_Q2JA30 Cluster: Thiamine pyrophosphate enzyme-like TPP
binding region; n=50; Bacteria|Rep: Thiamine
pyrophosphate enzyme-like TPP binding region - Frankia
sp. (strain CcI3)
Length = 599
Score = 54.8 bits (126), Expect = 2e-06
Identities = 36/126 (28%), Positives = 62/126 (49%), Gaps = 8/126 (6%)
Frame = +2
Query: 263 GVEYVFGIVGIPVIETAMAFQSAGLK--YIGMRNEQAACYAAQATGYLTGKPGVCLVVSG 436
GV +FG G + AF AG ++ R+E+ A + A A TG+ G C+ SG
Sbjct: 16 GVHRIFGYPGDGINGFLGAFDRAGGDPGFLQTRHEEMAAFMACAHAKFTGEVGACVATSG 75
Query: 437 PGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQVDSSRM------YCKYAA 598
PG +H + G+ +A+++ P++ I G + ++G + ++D + Y +Y
Sbjct: 76 PGAIHLLNGLYDARLDHQPVLAIVGQ--QRRTSLGAHYQ-QEIDLISLFKDVTEYVQYCM 132
Query: 599 RPPSPR 616
PPS R
Sbjct: 133 APPSAR 138
>UniRef50_Q11NN4 Cluster: Acetolactate synthase, large subunit; n=1;
Cytophaga hutchinsonii ATCC 33406|Rep: Acetolactate
synthase, large subunit - Cytophaga hutchinsonii (strain
ATCC 33406 / NCIMB 9469)
Length = 573
Score = 54.8 bits (126), Expect = 2e-06
Identities = 30/87 (34%), Positives = 47/87 (54%)
Frame = +2
Query: 293 IPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTGKPGVCLVVSGPGLLHCIGGMAN 472
+P+ + A+A+ S L + +R+EQ A + A +TG+PG CL SGPG + + G+A+
Sbjct: 34 LPIYD-ALAYSS--LNCVLVRHEQGASFMANGYARVTGRPGFCLATSGPGATNLVTGIAD 90
Query: 473 AQVNCWPLVVIAGSCPEDHEAIGGFQE 553
A + P+V I G FQE
Sbjct: 91 AYADSVPMVAITGQVALHLIGSDAFQE 117
>UniRef50_A5MZ19 Cluster: Acetolactate synthase; n=1; Clostridium
kluyveri DSM 555|Rep: Acetolactate synthase -
Clostridium kluyveri DSM 555
Length = 569
Score = 54.8 bits (126), Expect = 2e-06
Identities = 33/98 (33%), Positives = 51/98 (52%), Gaps = 1/98 (1%)
Frame = +2
Query: 221 IDGNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAG-LKYIGMRNEQAACYAAQATGY 397
I+ + ++A LK+ + +F G V A + G + + RN+QAA A A
Sbjct: 2 INISKMIANKLKENKCKVIFEYPGGNVAPILDAVKLDGTIDLVVTRNDQAASLMADAYAR 61
Query: 398 LTGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAG 511
+TG+ GVC+ GPG + + G+ANA + PLV I G
Sbjct: 62 VTGEVGVCMATVGPGATNLVTGIANAYFDSIPLVAITG 99
>UniRef50_A3U199 Cluster: Acetolactate synthase II large subunit;
n=2; Proteobacteria|Rep: Acetolactate synthase II large
subunit - Oceanicola batsensis HTCC2597
Length = 553
Score = 54.8 bits (126), Expect = 2e-06
Identities = 37/125 (29%), Positives = 59/125 (47%), Gaps = 4/125 (3%)
Frame = +2
Query: 236 ILAESLKKQGVEYVFGIVGIPVIETAMAFQSAG-LKYIGMRNEQAACYAAQATGYLTGKP 412
+LA SL + G++ VF + G + A L+ + R+E A + A A ++G+
Sbjct: 7 LLARSLIQHGIDRVFCVPGESYLSVLDAMVDVSELQVVTARHEGGAGFMAVADAKISGRT 66
Query: 413 GVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQVDSSRMY--- 583
GV V GPG ++ + AQ + P V+ G H + FQE VD S ++
Sbjct: 67 GVAFVSRGPGAMNAAIAVHTAQQDAVPFVLFVGQVERSHLGMNAFQE---VDHSLVFGSM 123
Query: 584 CKYAA 598
CK+ A
Sbjct: 124 CKWTA 128
>UniRef50_Q5UWG1 Cluster: Acetolactate synthase large subunit; n=1;
Haloarcula marismortui|Rep: Acetolactate synthase large
subunit - Haloarcula marismortui (Halobacterium
marismortui)
Length = 567
Score = 54.8 bits (126), Expect = 2e-06
Identities = 38/107 (35%), Positives = 52/107 (48%), Gaps = 2/107 (1%)
Frame = +2
Query: 239 LAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTGKPGV 418
L E L +QGVEYVFG G IE A ++ + R+E+ A A+ G LTG PGV
Sbjct: 8 LVEELDEQGVEYVFGYPGGRAIEILDHVPDADVEMVRPRDEREASVMAEMHGRLTGNPGV 67
Query: 419 CLVVSGP--GLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQE 553
L GP G L IG M + +V+ S D+ + +Q+
Sbjct: 68 -LAGQGPWIGSLGAIGQMEGKLASSPMVVITEASERGDYSTLAPYQQ 113
>UniRef50_A6LX01 Cluster: Thiamine pyrophosphate protein, central
region; n=1; Clostridium beijerinckii NCIMB 8052|Rep:
Thiamine pyrophosphate protein, central region -
Clostridium beijerinckii NCIMB 8052
Length = 543
Score = 54.4 bits (125), Expect = 2e-06
Identities = 29/93 (31%), Positives = 45/93 (48%)
Frame = +2
Query: 233 TILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTGKP 412
+IL + +K G+ VFG+ G P+ M + +I ++E A YAA + K
Sbjct: 6 SILVSNFRKWGINNVFGVPGRPLASLIMELDRQDINFILSKHESGAGYAAAGYSLINKKL 65
Query: 413 GVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAG 511
GV LV SGPG + + A+ P++ I G
Sbjct: 66 GVALVTSGPGGTNALTAAGQAKAYHVPVLFITG 98
>UniRef50_A0WA20 Cluster: Thiamine pyrophosphate enzyme-like TPP
binding region; n=1; Geobacter lovleyi SZ|Rep: Thiamine
pyrophosphate enzyme-like TPP binding region - Geobacter
lovleyi SZ
Length = 562
Score = 54.4 bits (125), Expect = 2e-06
Identities = 29/107 (27%), Positives = 51/107 (47%)
Frame = +2
Query: 236 ILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTGKPG 415
++ SL+K GV VFG+ G + A + + I ++E+ A + A ++G
Sbjct: 6 VIVRSLEKHGVTCVFGVPGGAIESLNTALYKSSISVIVAKHEEGAAFMADGYARVSGVIA 65
Query: 416 VCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEW 556
VC +GPG + I G+A+A + P++ + G G QE+
Sbjct: 66 VCCSTAGPGATNMITGIASAFGDSIPVIALTGQVSTSLFGKGAIQEF 112
>UniRef50_Q88Y01 Cluster: Acetolactate synthase; n=25; Bacilli|Rep:
Acetolactate synthase - Lactobacillus plantarum
Length = 560
Score = 54.0 bits (124), Expect = 3e-06
Identities = 32/99 (32%), Positives = 47/99 (47%), Gaps = 4/99 (4%)
Frame = +2
Query: 227 GNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSA----GLKYIGMRNEQAACYAAQATG 394
G + +SL V+YVFGI G + + + I R+EQ A + A G
Sbjct: 8 GADAIVDSLVNHDVKYVFGIPGAKIDRVFERLEHPVNPKSPRLIVTRHEQNAAFIAAGIG 67
Query: 395 YLTGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAG 511
+TGKPGV + SGPG + G+ A P++ I+G
Sbjct: 68 RITGKPGVVMTTSGPGASNLATGLVTATAEGDPVLAISG 106
>UniRef50_Q3A842 Cluster: Acetolactate synthase large subunit; n=2;
Pelobacter|Rep: Acetolactate synthase large subunit -
Pelobacter carbinolicus (strain DSM 2380 / Gra Bd 1)
Length = 580
Score = 54.0 bits (124), Expect = 3e-06
Identities = 35/110 (31%), Positives = 54/110 (49%), Gaps = 4/110 (3%)
Frame = +2
Query: 236 ILAESLKKQGVEYVFGIVGIPVIETAMAFQSA----GLKYIGMRNEQAACYAAQATGYLT 403
++ + L+ GVEYVFGI G P+ A + + G + + R+E A + A +
Sbjct: 6 LIVQYLESFGVEYVFGIPGSPLGPLFDALKRSEKRGGPRLVLTRHEAGAAFIADGYARES 65
Query: 404 GKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQE 553
GK GVC +GPG + I G+A+A P++VI G FQ+
Sbjct: 66 GKLGVCCSTTGPGATNLITGVASAYAEQVPMLVITPQTRLGALGFGCFQD 115
>UniRef50_Q11CB6 Cluster: Thiamine pyrophosphate enzyme-like
TPP-binding; n=5; Rhizobiales|Rep: Thiamine
pyrophosphate enzyme-like TPP-binding - Mesorhizobium
sp. (strain BNC1)
Length = 541
Score = 54.0 bits (124), Expect = 3e-06
Identities = 33/95 (34%), Positives = 52/95 (54%), Gaps = 2/95 (2%)
Frame = +2
Query: 236 ILAESLKKQGVEYVFGIVGIPVIE--TAMAFQSAGLKYIGMRNEQAACYAAQATGYLTGK 409
I+A+SL GV+ +FGI G + + A+A ++ +++I R+EQ A Y A +GK
Sbjct: 9 IIAKSLIANGVDTLFGISGAHMYDFNDAVAREAGAIRFIHTRHEQGAGYMAYGYAKSSGK 68
Query: 410 PGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGS 514
G VV GPGLL+ + A P++ I G+
Sbjct: 69 VGAYTVVPGPGLLNSGAALCTAYGANAPVLCITGN 103
>UniRef50_Q036H9 Cluster: Pyruvate oxidase; n=1; Lactobacillus casei
ATCC 334|Rep: Pyruvate oxidase - Lactobacillus casei
(strain ATCC 334)
Length = 586
Score = 54.0 bits (124), Expect = 3e-06
Identities = 39/132 (29%), Positives = 62/132 (46%), Gaps = 6/132 (4%)
Frame = +2
Query: 245 ESLKKQGVEYVFGIVG--IPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTGKPGV 418
++L+ GV +V+GI G + A+ + LKYI +R+E+ AA A G LTG GV
Sbjct: 13 KTLESWGVTHVYGIPGGTFNNMMYALDEEKDNLKYIHVRHEEVGALAAVADGKLTGHIGV 72
Query: 419 CLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEW---PQVDSSRMYCK 589
+GPG H G +A+++ P + + G + FQE P + +Y +
Sbjct: 73 AFGSAGPGATHLFQGAYDAKMDKVPTLFLVGQVEQRFMNYDFFQELDEDPMFQDAALYAR 132
Query: 590 YAARPPS-PRLI 622
S P +I
Sbjct: 133 TVTTAASLPHII 144
>UniRef50_A6BCA9 Cluster: Acetolactate synthase II large subunit;
n=1; Vibrio parahaemolyticus AQ3810|Rep: Acetolactate
synthase II large subunit - Vibrio parahaemolyticus
AQ3810
Length = 237
Score = 53.6 bits (123), Expect = 4e-06
Identities = 29/86 (33%), Positives = 41/86 (47%)
Frame = +2
Query: 317 AFQSAGLKYIGMRNEQAACYAAQATGYLTGKPGVCLVVSGPGLLHCIGGMANAQVNCWPL 496
A G+++I R+EQ A AA T VC+ SGPG + + G+A+A ++ PL
Sbjct: 150 ALYDGGVEHILCRHEQGAAMAAIGMARSTQDVAVCMATSGPGATNLVTGLADAFLDSVPL 209
Query: 497 VVIAGSCPEDHEAIGGFQEWPQVDSS 574
V I G H FQE + S
Sbjct: 210 VAITGQVASSHIGTDAFQEMDVIGMS 235
>UniRef50_A1SLX3 Cluster: Thiamine pyrophosphate enzyme domain
protein TPP-binding; n=2; Bacteria|Rep: Thiamine
pyrophosphate enzyme domain protein TPP-binding -
Nocardioides sp. (strain BAA-499 / JS614)
Length = 588
Score = 53.6 bits (123), Expect = 4e-06
Identities = 36/134 (26%), Positives = 62/134 (46%), Gaps = 3/134 (2%)
Frame = +2
Query: 218 GIDGNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGY 397
G+ G ++A+ L + V+ VFGI+ A G+ R+E AA + A A
Sbjct: 4 GLTGGQLIAKMLAAEAVDQVFGIIDGTYFGLYRALGDEGITLHSPRHEAAAAHMAGAYAR 63
Query: 398 LTGKPGVCLVVSGPGLLHCIGGMA--NAQVNCWPLVVIAGSCPEDHEAIGG-FQEWPQVD 568
++G+ GVC+ +GPG+ + + G+A + N L+ H GG +Q + Q
Sbjct: 64 VSGRLGVCMASNGPGVANVLPGVAVEQGEGNRILLITSGRRVGITHPDRGGTYQNFDQTA 123
Query: 569 SSRMYCKYAARPPS 610
+ K++ PS
Sbjct: 124 VTAPMAKWSCHVPS 137
>UniRef50_A1ULG6 Cluster: Thiamine pyrophosphate enzyme domain
protein TPP-binding; n=9; Actinomycetales|Rep: Thiamine
pyrophosphate enzyme domain protein TPP-binding -
Mycobacterium sp. (strain KMS)
Length = 571
Score = 53.2 bits (122), Expect = 5e-06
Identities = 27/99 (27%), Positives = 49/99 (49%)
Frame = +2
Query: 215 MGIDGNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATG 394
MG+ + + + +GV +FGI + ++ G + +E +A + A+A
Sbjct: 1 MGVPVYKRILDLFEAEGVNTLFGIPDPNFVHMFTEAEARGWSVVAPHHELSAGFMAEAAS 60
Query: 395 YLTGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAG 511
+TGKPG+C+ GPG+ + G M A V P++ + G
Sbjct: 61 RMTGKPGLCIGTLGPGVANIAGAMMCALVENSPVIFLGG 99
>UniRef50_Q8EC82 Cluster: Acetolactate synthase isozyme I, large
subunit; n=2; Shewanella|Rep: Acetolactate synthase
isozyme I, large subunit - Shewanella oneidensis
Length = 581
Score = 52.8 bits (121), Expect = 6e-06
Identities = 31/91 (34%), Positives = 46/91 (50%)
Frame = +2
Query: 239 LAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTGKPGV 418
+ E L QG++ G + A + G+ RNEQ A YAA A G LT PG+
Sbjct: 13 IIEFLAHQGIKAFHNYPGGTIAPLLDACKRFGVTVYTSRNEQGAGYAALAQGKLTQLPGI 72
Query: 419 CLVVSGPGLLHCIGGMANAQVNCWPLVVIAG 511
V SGPG+ + + +A+A + P++V G
Sbjct: 73 VAVTSGPGVTNVLTPVADAYFDGIPMLVFTG 103
>UniRef50_Q88U88 Cluster: Pyruvate oxidase; n=5;
Lactobacillaceae|Rep: Pyruvate oxidase - Lactobacillus
plantarum
Length = 585
Score = 52.8 bits (121), Expect = 6e-06
Identities = 30/116 (25%), Positives = 59/116 (50%), Gaps = 2/116 (1%)
Frame = +2
Query: 221 IDGNTILAESLKKQGVEYVFGIVGIPVIET--AMAFQSAGLKYIGMRNEQAACYAAQATG 394
I+ + + + ++ V+ ++G G T A+ + L+Y+ +R+EQ AA A
Sbjct: 5 IEASVAMLKVIEAWDVKQIYGYAGGSFNSTMHALDVEQERLQYVQVRHEQVGALAAAADA 64
Query: 395 YLTGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQ 562
LTGK GV +GPG ++ + G+ +A+ + P++ + G + FQE+ +
Sbjct: 65 KLTGKIGVAFGSAGPGAVNLLNGLYDAKEDHVPVLALVGQVAHTNMNYDYFQEFAE 120
>UniRef50_A7DF15 Cluster: Thiamine pyrophosphate enzyme TPP binding
domain protein; n=3; Alphaproteobacteria|Rep: Thiamine
pyrophosphate enzyme TPP binding domain protein -
Methylobacterium extorquens PA1
Length = 562
Score = 52.8 bits (121), Expect = 6e-06
Identities = 36/104 (34%), Positives = 51/104 (49%), Gaps = 3/104 (2%)
Frame = +2
Query: 227 GNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSA-GLKYIGMRNEQAACYAAQATGYLT 403
G +L E L+ +GV Y+FG G + A A + Y+ E +A A A GY
Sbjct: 14 GADVLLEVLRSEGVRYIFGNPGTTELPLIDALTDAPDIAYVLALQEASA--VAMADGYAQ 71
Query: 404 G--KPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDH 529
G +PG + + GL H +G + NAQ++ PLVV AG H
Sbjct: 72 GARRPGFLNLHTAGGLGHGMGNLLNAQISGTPLVVTAGQQDSRH 115
>UniRef50_Q92UW6 Cluster: Probable sulfoacetaldehyde
acetyltransferase; n=39; cellular organisms|Rep:
Probable sulfoacetaldehyde acetyltransferase - Rhizobium
meliloti (Sinorhizobium meliloti)
Length = 591
Score = 52.8 bits (121), Expect = 6e-06
Identities = 35/122 (28%), Positives = 55/122 (45%), Gaps = 2/122 (1%)
Frame = +2
Query: 251 LKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTGKPGVCLVV 430
L+ G+E+ FGI+G ++ + F AG+++ +E A A TG + +
Sbjct: 13 LQMHGIEHAFGIIGSAMMPVSDLFPKAGIRFWDCAHETNAGMMADGFSRATGTMSMAIGQ 72
Query: 431 SGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQVDS-SRMYC-KYAARP 604
+GPG+ I M A N PL+++ GGFQE Q+ M C + R
Sbjct: 73 NGPGVTGFITAMKTAYWNHTPLLMVTPQAANKTIGQGGFQEVDQMAMFEEMVCYQEEVRD 132
Query: 605 PS 610
PS
Sbjct: 133 PS 134
>UniRef50_Q8ZTD9 Cluster: Acetolactate synthase; n=5;
Thermoproteaceae|Rep: Acetolactate synthase -
Pyrobaculum aerophilum
Length = 556
Score = 52.4 bits (120), Expect = 8e-06
Identities = 29/91 (31%), Positives = 46/91 (50%)
Frame = +2
Query: 281 GIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTGKPGVCLVVSGPGLLHCIG 460
GI G ++ A ++ I R+EQ A +AA+ ++G+P V V SGPG + +
Sbjct: 2 GIPGGQIMPLFDALYGQDIETILFRHEQGAIHAAEGYARVSGRPAVVAVTSGPGATNLVT 61
Query: 461 GMANAQVNCWPLVVIAGSCPEDHEAIGGFQE 553
G+ +A ++ P+V I G GFQE
Sbjct: 62 GITDAYMDSTPVVAITGQVVTSVFGRDGFQE 92
>UniRef50_A0YVD9 Cluster: Indole-3-pyruvate decarboxylase; n=1;
Lyngbya sp. PCC 8106|Rep: Indole-3-pyruvate
decarboxylase - Lyngbya sp. PCC 8106
Length = 558
Score = 52.0 bits (119), Expect = 1e-05
Identities = 31/92 (33%), Positives = 46/92 (50%)
Frame = +2
Query: 239 LAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTGKPGV 418
L LK GV +VFG+ G V++ + ++ +G NE A YAA A L G +
Sbjct: 22 LVSQLKAVGVRHVFGVPGDYVLDLMDVIVESSIELVGTCNELNAGYAADAYARLNGVSAL 81
Query: 419 CLVVSGPGLLHCIGGMANAQVNCWPLVVIAGS 514
C V G G L + +A A P++VI+G+
Sbjct: 82 C-VTYGVGGLSVVNALAGAYAEEVPVIVISGA 112
>UniRef50_Q1GGF3 Cluster: Thiamine pyrophosphate enzyme-like
TPP-binding; n=3; Rhodobacteraceae|Rep: Thiamine
pyrophosphate enzyme-like TPP-binding - Silicibacter sp.
(strain TM1040)
Length = 537
Score = 51.6 bits (118), Expect = 1e-05
Identities = 29/100 (29%), Positives = 50/100 (50%)
Frame = +2
Query: 236 ILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTGKPG 415
ILA L + G + FG+ G V+ A AG+ + ++E A + + + G P
Sbjct: 10 ILARRLYEAGCRHAFGMPGGEVLTLVDALTRAGITFHLAKHENCAGFMGEGVHHSDGAPA 69
Query: 416 VCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEA 535
+ + GPG L+ + +ANA + P++V+ G C + EA
Sbjct: 70 ILVATLGPGALNGVNVVANAHQDRVPMLVLTG-CVDADEA 108
>UniRef50_A6G882 Cluster: Acetolactate synthase large subunit; n=1;
Plesiocystis pacifica SIR-1|Rep: Acetolactate synthase
large subunit - Plesiocystis pacifica SIR-1
Length = 639
Score = 51.6 bits (118), Expect = 1e-05
Identities = 28/103 (27%), Positives = 50/103 (48%)
Frame = +2
Query: 245 ESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTGKPGVCL 424
E L + G+E+ +GI G ++ A + L I R+E A +AA +G+P V
Sbjct: 88 EILGELGIEHAYGISGGAIVPFYDALSRSQLSVIHCRHEAGAAFAALEDSLASGRPTVVF 147
Query: 425 VVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQE 553
+GPG+ + + G+ A+ ++ I+ + P G FQ+
Sbjct: 148 TTTGPGITNALTGLVAARWEGAKVLFISAATPLAQTGRGAFQD 190
>UniRef50_Q13H77 Cluster: Putative pyruvate decarboxylase; n=1;
Burkholderia xenovorans LB400|Rep: Putative pyruvate
decarboxylase - Burkholderia xenovorans (strain LB400)
Length = 561
Score = 51.2 bits (117), Expect = 2e-05
Identities = 33/110 (30%), Positives = 55/110 (50%), Gaps = 3/110 (2%)
Frame = +2
Query: 263 GVEYVFGIVG---IPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTGKPGVCLVVS 433
G++ VF + G + +++ F S + + R+E A + A A LT +PGV +V
Sbjct: 33 GIDRVFLVPGESYLGILDALGDFPS--IDVVTCRHESGAGFMACADARLTRRPGVVMVSR 90
Query: 434 GPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQVDSSRMY 583
GPG + + A+ + PL+++ G P+ G FQE +D RMY
Sbjct: 91 GPGAANAAIAIHTAEQDAIPLILVVGQVPKQRLRKGAFQE---IDYGRMY 137
>UniRef50_A6X6D0 Cluster: Thiamine pyrophosphate protein central
region; n=2; Rhizobiales|Rep: Thiamine pyrophosphate
protein central region - Ochrobactrum anthropi (strain
ATCC 49188 / DSM 6882 / NCTC 12168)
Length = 583
Score = 51.2 bits (117), Expect = 2e-05
Identities = 33/112 (29%), Positives = 57/112 (50%), Gaps = 3/112 (2%)
Frame = +2
Query: 227 GNTILAESLKKQGVEYVFGIVG---IPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGY 397
G IL + L GVE +FG+ G +P E A+ + ++++ R+E++A Y A A G
Sbjct: 3 GADILVQMLIGYGVETIFGVPGDTNVPFYE-ALQQREGEIRHVMARDERSAGYMADAYGR 61
Query: 398 LTGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQE 553
+ KPGV SG G ++ + +A + + P++++ P E G E
Sbjct: 62 FSNKPGVFECPSGAGAMYSLPPVAESNGSSIPVILLTIDIPLPGEGRGVLTE 113
>UniRef50_A1G7W2 Cluster: Thiamine pyrophosphate enzyme-like TPP
binding region; n=3; Actinomycetales|Rep: Thiamine
pyrophosphate enzyme-like TPP binding region -
Salinispora arenicola CNS205
Length = 568
Score = 51.2 bits (117), Expect = 2e-05
Identities = 30/107 (28%), Positives = 53/107 (49%), Gaps = 2/107 (1%)
Frame = +2
Query: 239 LAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGM--RNEQAACYAAQATGYLTGKP 412
+A +L + GV +VFG+ G + + A + G+ ++E +A A + +TG+
Sbjct: 11 IAATLARLGVRHVFGVSGANIEDLYDALRGTDGATCGVVAKHEFSAATMADGSARVTGRF 70
Query: 413 GVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQE 553
GV SG ++ + G+A A + P++ + G P E G FQE
Sbjct: 71 GVVSTTSGGAAMNLVPGLAEAYASRVPMLALVGQPPTAQEGRGAFQE 117
>UniRef50_Q6D799 Cluster: Putative thiamine pyrophosphate enzyme;
n=1; Pectobacterium atrosepticum|Rep: Putative thiamine
pyrophosphate enzyme - Erwinia carotovora subsp.
atroseptica (Pectobacterium atrosepticum)
Length = 598
Score = 50.8 bits (116), Expect = 3e-05
Identities = 29/92 (31%), Positives = 48/92 (52%), Gaps = 1/92 (1%)
Frame = +2
Query: 239 LAESLKKQGVEYVFGIVGIPVIETAMAF-QSAGLKYIGMRNEQAACYAAQATGYLTGKPG 415
+ + L+ GV+ VF + G ++ A + G+ Y+ +EQA+ AA A L+GK G
Sbjct: 9 IVQHLRNIGVDTVFLLNGGGMMHMVDALARCEGMHYVCSHHEQASAIAADAYARLSGKLG 68
Query: 416 VCLVVSGPGLLHCIGGMANAQVNCWPLVVIAG 511
VC +GPG + + G+ A + P + I G
Sbjct: 69 VCYATAGPGATNILTGVVGAWQDSSPALFITG 100
>UniRef50_Q54FW8 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 686
Score = 50.8 bits (116), Expect = 3e-05
Identities = 30/96 (31%), Positives = 49/96 (51%), Gaps = 1/96 (1%)
Frame = +2
Query: 224 DGNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAG-LKYIGMRNEQAACYAAQATGYL 400
+G +++ L +++ F + + I+T +K I M+N A AA +
Sbjct: 88 NGGNVISRVLNNHNIKFAFSLSELQDIKTINECSLENKMKVIQMKNYNNAIVAAGGVFRM 147
Query: 401 TGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIA 508
TG+ GV V GP ++ I G+ NA+V+ PLVVIA
Sbjct: 148 TGQIGVVFVNGGPEIISMINGIVNAKVDNIPLVVIA 183
>UniRef50_A1R2T4 Cluster: Putative acetolactate synthase, large
subunit; n=2; Micrococcineae|Rep: Putative acetolactate
synthase, large subunit - Arthrobacter aurescens (strain
TC1)
Length = 539
Score = 50.4 bits (115), Expect = 3e-05
Identities = 28/114 (24%), Positives = 50/114 (43%)
Frame = +2
Query: 215 MGIDGNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATG 394
M ++ L++ G++ V+ + G ++ + ++ + R E A + A A G
Sbjct: 1 MSTTAGHLIVGQLERAGIKRVYTVPGESFLDVLDGLHGSPIQNVVARQEGGAGFMALAEG 60
Query: 395 YLTGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEW 556
LT PGV +V GPG + + A + PL++ G P FQE+
Sbjct: 61 RLTELPGVAMVTRGPGAANAFIAVHTAYQDATPLILFVGLIPVADRGRESFQEF 114
>UniRef50_A0W3U9 Cluster: Thiamine pyrophosphate enzyme-like TPP
binding region; n=1; Geobacter lovleyi SZ|Rep: Thiamine
pyrophosphate enzyme-like TPP binding region - Geobacter
lovleyi SZ
Length = 550
Score = 50.4 bits (115), Expect = 3e-05
Identities = 35/116 (30%), Positives = 53/116 (45%)
Frame = +2
Query: 230 NTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTGK 409
+T L + LK+ GV ++FG+ G V++ + L ++G NE A YAA L G
Sbjct: 8 STYLLQRLKELGVNHLFGVPGDYVLDFLDQVIESPLAWVGTCNELNAGYAADGYARLNGL 67
Query: 410 PGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQVDSSR 577
G +V G G + +A A PLV+I+G+ P G D +R
Sbjct: 68 GG-AVVTYGVGGFSILNAVAGAFAEMVPLVLISGAPPTGRRKAGALVHHLVADYNR 122
>UniRef50_A2Q9V6 Cluster: Catalytic activity: 2-acetolactate + CO(2)
<=> 2 pyruvate; n=1; Aspergillus niger|Rep: Catalytic
activity: 2-acetolactate + CO(2) <=> 2 pyruvate -
Aspergillus niger
Length = 253
Score = 50.4 bits (115), Expect = 3e-05
Identities = 39/135 (28%), Positives = 63/135 (46%), Gaps = 9/135 (6%)
Frame = +2
Query: 215 MGIDGNTILAESLKKQGVEYVFGIVG---IPVIETAMAFQSAGLKYIGMRNEQAACYAAQ 385
+G G I E ++ V+++FG G +P+++ A S L +I ++EQ+A + A+
Sbjct: 80 IGKTGGQIFHEMMRLHNVKHIFGYPGGTILPILDALYA--SPHLTFILPKHEQSAGHMAE 137
Query: 386 ATGYLTGK------PGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGF 547
GY PG+ LV SGPG + I + NA + PL+ G GF
Sbjct: 138 --GYARASISSYPTPGIVLVTSGPGATNLITPLQNALSDGTPLIAFCGQVATSAIGKDGF 195
Query: 548 QEWPQVDSSRMYCKY 592
QE + +R K+
Sbjct: 196 QEADVLGMTRFCTKW 210
>UniRef50_Q54970 Cluster: Pyruvate oxidase; n=21;
Lactobacillales|Rep: Pyruvate oxidase - Streptococcus
pneumoniae
Length = 591
Score = 50.4 bits (115), Expect = 3e-05
Identities = 32/116 (27%), Positives = 56/116 (48%), Gaps = 2/116 (1%)
Frame = +2
Query: 221 IDGNTILAESLKKQGVEYVFGIVG--IPVIETAMAFQSAGLKYIGMRNEQAACYAAQATG 394
I + + LK GV+ ++GI + + A+A + ++++ +R+E+ AA
Sbjct: 6 ITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALA-EDKDIRFLQVRHEETGALAAVMQA 64
Query: 395 YLTGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQ 562
G GV + GPG H I G+ +A ++ P + I GS P + + FQE Q
Sbjct: 65 KFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAILGSRPVNELNMDAFQELNQ 120
>UniRef50_A1WXE6 Cluster: Acetolactate synthase; n=6;
Proteobacteria|Rep: Acetolactate synthase -
Halorhodospira halophila (strain DSM 244 / SL1)
(Ectothiorhodospirahalophila (strain DSM 244 / SL1))
Length = 628
Score = 50.0 bits (114), Expect = 4e-05
Identities = 37/130 (28%), Positives = 56/130 (43%), Gaps = 14/130 (10%)
Frame = +2
Query: 221 IDGNTILAESLKKQGVEYVFGIVGIPVIETAMAF--------------QSAGLKYIGMRN 358
+ G I+ E L ++GV+ +FG G ++ T A + ++ I N
Sbjct: 24 MSGGEIIVEVLAQEGVDTLFGYSGGAILPTYDAIFKYNERHRKEQAVEEEDPIRLIVPAN 83
Query: 359 EQAACYAAQATGYLTGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAI 538
EQ A + A TGK G LV SGPG + + + + + P+V I G P
Sbjct: 84 EQGAGFMAAGYARATGKVGCFLVTSGPGATNTVTPIRDCMADSVPVVAITGQVPTHAMGT 143
Query: 539 GGFQEWPQVD 568
FQE P V+
Sbjct: 144 DAFQEAPIVN 153
>UniRef50_Q7WPE1 Cluster: Thiamine pyrophosphate enzyme; n=2;
Proteobacteria|Rep: Thiamine pyrophosphate enzyme -
Bordetella bronchiseptica (Alcaligenes bronchisepticus)
Length = 558
Score = 49.6 bits (113), Expect = 6e-05
Identities = 31/85 (36%), Positives = 43/85 (50%), Gaps = 2/85 (2%)
Frame = +2
Query: 227 GNTILAESLKKQGVEYVFGIVGIPVIETAMAFQS-AG-LKYIGMRNEQAACYAAQATGYL 400
G + E L + GV+ +F I GI + A + AG + R+EQ Y A +
Sbjct: 7 GGEVFVEGLVRNGVKDLFFIPGIQLDWAVEALRKRAGEINLYVPRHEQTTTYMADGYYRV 66
Query: 401 TGKPGVCLVVSGPGLLHCIGGMANA 475
TGKPG +VV GPG L+ G+A A
Sbjct: 67 TGKPGTAMVVPGPGALNAGAGLATA 91
>UniRef50_Q0K1D6 Cluster: Indole-3-pyruvate decarboxylase; n=2;
Burkholderiaceae|Rep: Indole-3-pyruvate decarboxylase -
Ralstonia eutropha (strain ATCC 17699 / H16 / DSM 428 /
Stanier 337)(Cupriavidus necator (strain ATCC 17699 /
H16 / DSM 428 / Stanier337))
Length = 583
Score = 49.6 bits (113), Expect = 6e-05
Identities = 34/97 (35%), Positives = 47/97 (48%), Gaps = 1/97 (1%)
Frame = +2
Query: 233 TILAESLKKQGVEYVFGIVGIPVIETAMAFQSA-GLKYIGMRNEQAACYAAQATGYLTGK 409
T LA LK+ GV +VFG+ G + A G++++G NE A YAA +G
Sbjct: 7 TFLARRLKEAGVRHVFGVPGDFNLSFLEQIHDARGIEFVGNCNELNAAYAADGYARTSGL 66
Query: 410 PGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCP 520
+ G G L IGG+A A P+V I G+ P
Sbjct: 67 AAF-VTTFGVGDLAAIGGIAGAYAENVPVVHITGAPP 102
>UniRef50_A0QXQ7 Cluster: Putative acetolactate synthase; n=1;
Mycobacterium smegmatis str. MC2 155|Rep: Putative
acetolactate synthase - Mycobacterium smegmatis (strain
ATCC 700084 / mc(2)155)
Length = 539
Score = 49.6 bits (113), Expect = 6e-05
Identities = 28/96 (29%), Positives = 47/96 (48%)
Frame = +2
Query: 239 LAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTGKPGV 418
+A L V+ VFG++G + AF++AG + + +E A A +TG+ GV
Sbjct: 7 VARLLSGYAVDTVFGLLGDANMYVCSAFEAAGGRLVRTSHEAGAVSMADTYARMTGRWGV 66
Query: 419 CLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPED 526
V GPGL + + + A P+++I G P +
Sbjct: 67 AAVTHGPGLTNALTPLVEAARFPSPILLITGDTPAE 102
>UniRef50_Q1YQE9 Cluster: Acetolactate synthase, large subunit; n=1;
gamma proteobacterium HTCC2207|Rep: Acetolactate
synthase, large subunit - gamma proteobacterium HTCC2207
Length = 579
Score = 49.2 bits (112), Expect = 8e-05
Identities = 31/102 (30%), Positives = 52/102 (50%), Gaps = 2/102 (1%)
Frame = +2
Query: 215 MGIDGNTILAESLKKQGVEYVFGIVGIPVIETAMAF-QSAGLKYIGMRNEQAACYAAQAT 391
M +G + +L++ G+ + FGI G+ E QS + + + +E A + A A
Sbjct: 1 MNKNGAWLTQYALEQLGITHTFGIPGVQNAEIYDHLNQSESITPLLVNHEMNAAFMADAV 60
Query: 392 GYLT-GKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGS 514
+ G G L+VSG G+ H I G+ A + PL++IAG+
Sbjct: 61 SRTSAGSVGTMLIVSGSGVTHAISGIGEAYLAGIPLLIIAGA 102
>UniRef50_Q0JYE0 Cluster: Acetolactate synthase large subunit; n=1;
Ralstonia eutropha H16|Rep: Acetolactate synthase large
subunit - Ralstonia eutropha (strain ATCC 17699 / H16 /
DSM 428 / Stanier 337)(Cupriavidus necator (strain ATCC
17699 / H16 / DSM 428 / Stanier337))
Length = 549
Score = 49.2 bits (112), Expect = 8e-05
Identities = 26/97 (26%), Positives = 49/97 (50%), Gaps = 2/97 (2%)
Frame = +2
Query: 227 GNTILAESLKKQGVEYVFGIVGIPVIET--AMAFQSAGLKYIGMRNEQAACYAAQATGYL 400
G +LA+ +++ G +VF I G ++E A+A + + + R+E YAAQA L
Sbjct: 6 GAAVLADLIREYGHRHVFQIPGEGILEPLDALATRHPEISLVTFRHEAGMTYAAQAYARL 65
Query: 401 TGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAG 511
+P +C+ PG L+ + A + ++++ G
Sbjct: 66 GDRPSICMAGRAPGALNTALALHTADTDSAAMILVVG 102
>UniRef50_A4XBS4 Cluster: Thiamine pyrophosphate enzyme domain
protein TPP-binding; n=1; Salinispora tropica
CNB-440|Rep: Thiamine pyrophosphate enzyme domain
protein TPP-binding - Salinispora tropica CNB-440
Length = 574
Score = 49.2 bits (112), Expect = 8e-05
Identities = 31/115 (26%), Positives = 50/115 (43%), Gaps = 3/115 (2%)
Frame = +2
Query: 218 GIDGNTILAESLKKQGVEYVF---GIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQA 388
G+ L L+ G ++F G + P + G I E A Y A
Sbjct: 5 GVVVTEYLIRMLRDHGARHIFIGLGALNDPFMSPLSTVDGVGT--IVTAFEGGAAYMADG 62
Query: 389 TGYLTGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQE 553
+G G+CL + GPG+L+ +A A+ + ++VI+G P +GGFQ+
Sbjct: 63 YARASGGIGLCLGIGGPGVLNMTTALAGAKTDRSSVIVISGEVPRSWAGMGGFQD 117
>UniRef50_A3U0U7 Cluster: Acetolactate synthase, large subunit; n=1;
Oceanicola batsensis HTCC2597|Rep: Acetolactate
synthase, large subunit - Oceanicola batsensis HTCC2597
Length = 577
Score = 49.2 bits (112), Expect = 8e-05
Identities = 36/128 (28%), Positives = 53/128 (41%)
Frame = +2
Query: 227 GNTILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTG 406
G LA L+ +FG+ G ++ A + GL + + +E+ +AA A +TG
Sbjct: 11 GGEALARMLQAHNTGPIFGMGGFQLLPFYDAARRLGLNHNLINDERCGVFAADAYAKVTG 70
Query: 407 KPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQVDSSRMYC 586
+ GV GPG + + G+ A PLV I G H QE Q + R
Sbjct: 71 RVGVVDATLGPGATNLVTGLVEALNAGSPLVAIVGDSHRAHSWKNMTQEARQAEILRPAV 130
Query: 587 KYAARPPS 610
K R S
Sbjct: 131 KELLRAES 138
>UniRef50_Q2FN41 Cluster: Thiamine pyrophosphate enzyme-like
TPP-binding; n=2; Methanomicrobiales|Rep: Thiamine
pyrophosphate enzyme-like TPP-binding - Methanospirillum
hungatei (strain JF-1 / DSM 864)
Length = 591
Score = 49.2 bits (112), Expect = 8e-05
Identities = 32/111 (28%), Positives = 53/111 (47%), Gaps = 3/111 (2%)
Frame = +2
Query: 239 LAESLKKQGVEYVFGIVG---IPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTGK 409
+ E+L G+ FG+ G + +I+ + A R+E+ A AA A LTGK
Sbjct: 69 IIENLVHFGITEYFGVPGTSSLGIIDAIRKHERANFTLF--RHEENAAMAASAYNKLTGK 126
Query: 410 PGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQ 562
C+ ++GPG + G+ +A+ + ++ I G + GGFQE Q
Sbjct: 127 VAACVTIAGPGATNLATGLYDAKEDRASVLSINGQVEMQYAGPGGFQEIDQ 177
>UniRef50_Q9LCV9 Cluster: Carboxyethylarginine synthase; n=3;
Streptomyces clavuligerus|Rep: Carboxyethylarginine
synthase - Streptomyces clavuligerus
Length = 573
Score = 48.4 bits (110), Expect = 1e-04
Identities = 28/98 (28%), Positives = 49/98 (50%)
Frame = +2
Query: 239 LAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTGKPGV 418
L L+ GV VFG+VG + + + G+ ++ R+E A AA +TG+P
Sbjct: 18 LLSRLRDHGVGKVFGVVGREAA-SILFDEVEGIDFVLTRHEFTAGVAADVLARITGRPQA 76
Query: 419 CLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHE 532
C GPG+ + G+A + ++ P++ +A E H+
Sbjct: 77 CWATLGPGMTNLSTGIATSVLDRSPVIALAAQ-SESHD 113
>UniRef50_A3JR28 Cluster: Putative uncharacterized protein; n=1;
Rhodobacterales bacterium HTCC2150|Rep: Putative
uncharacterized protein - Rhodobacterales bacterium
HTCC2150
Length = 538
Score = 48.4 bits (110), Expect = 1e-04
Identities = 25/94 (26%), Positives = 47/94 (50%), Gaps = 4/94 (4%)
Frame = +2
Query: 251 LKKQGVEYVFGIVGIPVIETA----MAFQSAGLKYIGMRNEQAACYAAQATGYLTGKPGV 418
L + G+ FGI G+ ++ + + G+ +I RNEQ A + A+ TG+ G+
Sbjct: 13 LGRYGLTKAFGIPGVHTLDLCRGLNLGANAGGITHIQARNEQGAGFMAEGWARCTGEVGL 72
Query: 419 CLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCP 520
+V+SGPG+ + + + P ++I+ P
Sbjct: 73 AIVISGPGVTNTATALGQCYGDSLPFLLISAEQP 106
>UniRef50_Q0U8P2 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 598
Score = 48.4 bits (110), Expect = 1e-04
Identities = 29/93 (31%), Positives = 44/93 (47%), Gaps = 1/93 (1%)
Frame = +2
Query: 245 ESLKKQGVEYVFGIVGIPVIETA-MAFQSAGLKYIGMRNEQAACYAAQATGYLTGKPGVC 421
E + + GV+ +FG+ G ++ F GLK+IG NE A YAA + G PG
Sbjct: 17 ERIHQIGVDTIFGVPGDFNLQFLDYLFHVDGLKWIGNMNELNASYAADGYARVKGVPGCV 76
Query: 422 LVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCP 520
+ G G L + G+A A ++ + G P
Sbjct: 77 VTTHGVGELSALNGVAGAMSEQVKIIHVVGQTP 109
>UniRef50_Q6N2Y1 Cluster: Possible acetolactate synthase large
subunit; n=2; Rhodopseudomonas palustris|Rep: Possible
acetolactate synthase large subunit - Rhodopseudomonas
palustris
Length = 600
Score = 48.0 bits (109), Expect = 2e-04
Identities = 40/132 (30%), Positives = 57/132 (43%), Gaps = 8/132 (6%)
Frame = +2
Query: 251 LKKQGVEYVFGIVGIPVIETAMAFQS-AGLKYIGMRNEQAACYAAQATGYLTGKPGVCLV 427
L ++GV +VFGI G + + Q + I ++EQAA AA TG+ GV +
Sbjct: 11 LARRGVTHVFGISGGAAVHMFDSAQRHPDVTPIFPQHEQAAAMAADGYARATGRLGVAIT 70
Query: 428 VSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIG-------GFQEWPQVDSSRMYC 586
SGPG + + G+ A + P ++I G H G GFQE
Sbjct: 71 TSGPGATNLLTGVCCAYYDSVPTLMITGQV-ATHRLKGKNQIRQLGFQETDVTSIFATVT 129
Query: 587 KYAARPPSPRLI 622
KYA + P I
Sbjct: 130 KYAVQISDPTTI 141
>UniRef50_A7D6S4 Cluster: Thiamine pyrophosphate enzyme domain
protein TPP-binding; n=1; Halorubrum lacusprofundi ATCC
49239|Rep: Thiamine pyrophosphate enzyme domain protein
TPP-binding - Halorubrum lacusprofundi ATCC 49239
Length = 582
Score = 47.6 bits (108), Expect = 2e-04
Identities = 35/129 (27%), Positives = 58/129 (44%), Gaps = 7/129 (5%)
Frame = +2
Query: 194 SQKLNGSMGIDGNTI---LAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQ 364
SQ +D T+ + + + +G++ FGI G + A +++ R+E
Sbjct: 6 SQSGTDPSAVDAPTVAEAVVDCMLDRGIDVAFGIPGKQTLPLNRALGERDARFVVARHET 65
Query: 365 AACYAAQATGYL-TGKPGVC---LVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHE 532
A + QA GY T PG +VV GPG ++ + G+ NA +C PL+ +A +
Sbjct: 66 AVTH--QAWGYAETSDPGAMAASIVVPGPGDMNAMNGLKNALNDCVPLLHLAVETEREVR 123
Query: 533 AIGGFQEWP 559
G E P
Sbjct: 124 GGDGIHETP 132
>UniRef50_A0VEM6 Cluster: Thiamine pyrophosphate enzyme-like
TPP-binding; n=2; Proteobacteria|Rep: Thiamine
pyrophosphate enzyme-like TPP-binding - Delftia
acidovorans SPH-1
Length = 575
Score = 47.2 bits (107), Expect = 3e-04
Identities = 30/122 (24%), Positives = 52/122 (42%)
Frame = +2
Query: 236 ILAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTGKPG 415
++A LK+ G+ FG +P + +A + GL+ I R E A Y A A ++G+P
Sbjct: 19 LVARVLKRHGITQFFG-QSLPSM-FVLAAEELGLRQIAYRTENAGGYMADAHARMSGRPA 76
Query: 416 VCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQVDSSRMYCKYA 595
V +GP + +A A P++ + D FQ+ + + K+
Sbjct: 77 VITAQNGPAAALLVAPLAEALKVSIPIIALVQDVARDQTDRNAFQDLDHMGLFKPVTKWV 136
Query: 596 AR 601
R
Sbjct: 137 RR 138
>UniRef50_Q2W979 Cluster: Thiamine pyrophosphate-requiring enzyme;
n=1; Magnetospirillum magneticum AMB-1|Rep: Thiamine
pyrophosphate-requiring enzyme - Magnetospirillum
magneticum (strain AMB-1 / ATCC 700264)
Length = 613
Score = 46.8 bits (106), Expect = 4e-04
Identities = 33/122 (27%), Positives = 54/122 (44%), Gaps = 7/122 (5%)
Frame = +2
Query: 251 LKKQGVEYVFGIVGIPVIETAMAFQSAG-LKYIGMRNEQAACYAAQATGYLTGKPGVCLV 427
L ++G++ +F + G + AF +Y+ +EQ +AA+A + G PG +
Sbjct: 11 LAEEGIDKIFVVYGAANGDLIDAFTRTNKTEYVATMHEQGGGFAAEAYAKIKGIPGATIA 70
Query: 428 VSGPGLLHCIGGMANAQVNCWPLVVIAGSC------PEDHEAIGGFQEWPQVDSSRMYCK 589
SGPG + + M N + P V + G P+ GFQE V ++ K
Sbjct: 71 TSGPGGQNLLTSMGNCFYDSIPCVFMTGQINSQFLRPDPSIRQVGFQETDIVGMAKPVTK 130
Query: 590 YA 595
YA
Sbjct: 131 YA 132
>UniRef50_Q7P747 Cluster: Acetolactate synthase; n=1; Fusobacterium
nucleatum subsp. vincentii ATCC 49256|Rep: Acetolactate
synthase - Fusobacterium nucleatum subsp. vincentii ATCC
49256
Length = 592
Score = 46.8 bits (106), Expect = 4e-04
Identities = 27/93 (29%), Positives = 48/93 (51%), Gaps = 1/93 (1%)
Frame = +2
Query: 236 ILAESLKKQGVEYVFGIVGIPVIETAMAFQ-SAGLKYIGMRNEQAACYAAQATGYLTGKP 412
++ E+L K ++ F +VG + A + ++ I +EQA AA+ +TG+
Sbjct: 8 LIFETLVKYNIKTCFAVVGGGAMHLDNALGLNKDIEKIFNHHEQACTIAAEGYAKITGQM 67
Query: 413 GVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAG 511
V SGPG + I G+ A V+ P++V++G
Sbjct: 68 AAACVTSGPGATNAITGVMGAWVDSVPMIVLSG 100
>UniRef50_Q7NR95 Cluster: Acetolactate synthase; n=1;
Chromobacterium violaceum|Rep: Acetolactate synthase -
Chromobacterium violaceum
Length = 577
Score = 46.4 bits (105), Expect = 6e-04
Identities = 32/106 (30%), Positives = 48/106 (45%), Gaps = 6/106 (5%)
Frame = +2
Query: 323 QSAGLKYIGMRNEQAACYAAQATGYLTGKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVV 502
Q + + +EQA AA+A G L + GV +V +GPG + + +A A + PL+V
Sbjct: 9 QQPDIAAVHCHHEQACGIAAEAYGRLAERTGVAMVTTGPGATNILTPVAGAWIESLPLLV 68
Query: 503 IAGSCPEDHEAIG------GFQEWPQVDSSRMYCKYAARPPSPRLI 622
I+G G G QE V ++ KYA P+ I
Sbjct: 69 ISGQVKRADLLQGSGLRQKGVQEVDVVSMAKPVTKYAVTVTDPQAI 114
>UniRef50_Q2SM62 Cluster: Thiamine pyrophosphate-requiring enzyme;
n=1; Hahella chejuensis KCTC 2396|Rep: Thiamine
pyrophosphate-requiring enzyme - Hahella chejuensis
(strain KCTC 2396)
Length = 601
Score = 46.4 bits (105), Expect = 6e-04
Identities = 33/110 (30%), Positives = 54/110 (49%), Gaps = 4/110 (3%)
Frame = +2
Query: 236 ILAESLKKQGVEYVFGIVG--IPVIETAMAFQ--SAGLKYIGMRNEQAACYAAQATGYLT 403
++ + L V YVFG+ G I + +A+A + +++I R+E A + A +
Sbjct: 21 LIVKYLSLLKVPYVFGVSGGNIDPLGSALARHEDNTHVRWILTRSEAGAGFMADGFARES 80
Query: 404 GKPGVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQE 553
G GVC SGPG + + ++NA V+ P++VI G G QE
Sbjct: 81 GVIGVCSATSGPGCTNLLTPVSNAFVDSVPMLVITGQSTISTFGRGAMQE 130
>UniRef50_Q9K659 Cluster: Acetolactate synthase large subunit; n=2;
Bacillus|Rep: Acetolactate synthase large subunit -
Bacillus halodurans
Length = 543
Score = 46.0 bits (104), Expect = 7e-04
Identities = 31/102 (30%), Positives = 48/102 (47%), Gaps = 1/102 (0%)
Frame = +2
Query: 251 LKKQGVEYVFGI-VGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTGKPGVCLV 427
L K GV+ VFGI G + + + ++E AA Y A A +G+ V +
Sbjct: 11 LAKGGVDTVFGIPAGSVNAFFDELYSMPQMTPVIAKHEGAASYMAAAYAKYSGQLAVAIG 70
Query: 428 VSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQE 553
SGPG + + G ANA P++ + G+ P + E + QE
Sbjct: 71 CSGPGSTNLLTGAANAMREQLPILFLTGAVPTNTEGLNASQE 112
>UniRef50_Q3A0L4 Cluster: Pyruvate decarboxylase; n=3; Bacteria|Rep:
Pyruvate decarboxylase - Pelobacter carbinolicus (strain
DSM 2380 / Gra Bd 1)
Length = 547
Score = 46.0 bits (104), Expect = 7e-04
Identities = 32/92 (34%), Positives = 45/92 (48%)
Frame = +2
Query: 239 LAESLKKQGVEYVFGIVGIPVIETAMAFQSAGLKYIGMRNEQAACYAAQATGYLTGKPGV 418
L L GVE+VFG+ G V++ +++ LK + +EQ A +AA A L G V
Sbjct: 11 LIRRLADYGVEHVFGVPGDYVLQFYQQLENSPLKVVNTCDEQGAGFAADAYARLRGLGVV 70
Query: 419 CLVVSGPGLLHCIGGMANAQVNCWPLVVIAGS 514
C+ G L A A PLVVI+G+
Sbjct: 71 CVTYCVGG-LKIANTTAQAFAEKSPLVVISGA 101
>UniRef50_Q9Y8X5 Cluster: Putative acetolactate synthase; n=1;
Aeropyrum pernix|Rep: Putative acetolactate synthase -
Aeropyrum pernix
Length = 556
Score = 46.0 bits (104), Expect = 7e-04
Identities = 32/127 (25%), Positives = 56/127 (44%), Gaps = 2/127 (1%)
Frame = +2
Query: 239 LAESLKKQGVEYVFGIVGIPVIETAMAFQSAG--LKYIGMRNEQAACYAAQATGYLTGKP 412
+A L GV ++GI+G +++ A + ++ R+EQ A AA A T +
Sbjct: 8 IARGLVAAGVARIYGIIGTSIVDFVDALYDYRDRIDFVTTRHEQVAVSAADAEYRSTRRL 67
Query: 413 GVCLVVSGPGLLHCIGGMANAQVNCWPLVVIAGSCPEDHEAIGGFQEWPQVDSSRMYCKY 592
V +GPG L+ + + A + PL++++G + + E Q +R KY
Sbjct: 68 AAAAVHAGPGFLNTLISLGIAAKDRVPLLLVSGGVRRRLRGLDAWLEVDQASIARPLVKY 127
Query: 593 AARPPSP 613
SP
Sbjct: 128 YGVLDSP 134
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 684,806,878
Number of Sequences: 1657284
Number of extensions: 14531218
Number of successful extensions: 31668
Number of sequences better than 10.0: 356
Number of HSP's better than 10.0 without gapping: 30605
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 31585
length of database: 575,637,011
effective HSP length: 97
effective length of database: 414,880,463
effective search space used: 45221970467
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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