Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= bmmt5n15
(625 letters)
Database: celegans
27,780 sequences; 12,740,198 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
U39852-7|AAK39260.1| 240|Caenorhabditis elegans Ground-like (gr... 36 0.024
U40799-6|AAA81484.2| 210|Caenorhabditis elegans Ground-like (gr... 35 0.054
Z78540-6|CAD30431.1| 887|Caenorhabditis elegans Hypothetical pr... 33 0.17
Z78540-5|CAB01738.2| 793|Caenorhabditis elegans Hypothetical pr... 33 0.17
Z72501-3|CAD30430.1| 887|Caenorhabditis elegans Hypothetical pr... 33 0.17
AJ133838-1|CAB44432.1| 793|Caenorhabditis elegans DYC-1 protein... 33 0.17
Z99279-6|CAB16498.1| 640|Caenorhabditis elegans Hypothetical pr... 31 0.67
Z82284-8|CAB05294.1| 640|Caenorhabditis elegans Hypothetical pr... 31 0.67
U37429-11|AAA79352.1| 312|Caenorhabditis elegans Hypothetical p... 30 1.5
Z70309-6|CAA94360.1| 324|Caenorhabditis elegans Hypothetical pr... 29 3.6
U41543-12|AAZ91345.1| 401|Caenorhabditis elegans Groundhog (hed... 29 3.6
Z69884-5|CAA93747.1| 423|Caenorhabditis elegans Hypothetical pr... 28 4.7
U80448-6|AAO12417.1| 687|Caenorhabditis elegans Hypothetical pr... 28 4.7
U80448-5|AAB37819.1| 975|Caenorhabditis elegans Hypothetical pr... 28 4.7
U55854-1|AAA98010.2| 418|Caenorhabditis elegans Hypothetical pr... 28 4.7
AF067211-1|AAC16986.1| 455|Caenorhabditis elegans Hypothetical ... 28 4.7
U46675-7|AAB52641.1| 1274|Caenorhabditis elegans Hypothetical pr... 28 6.2
AL161712-8|CAC70133.1| 340|Caenorhabditis elegans Hypothetical ... 28 6.2
AF016448-12|AAB65959.1| 316|Caenorhabditis elegans Hypothetical... 28 6.2
AC024772-3|AAF60538.1| 2344|Caenorhabditis elegans Hypothetical ... 28 6.2
Z74031-3|CAA98455.1| 245|Caenorhabditis elegans Hypothetical pr... 27 8.2
Z68314-9|CAA92667.2| 2862|Caenorhabditis elegans Hypothetical pr... 27 8.2
Z66497-12|CAA91289.2| 2862|Caenorhabditis elegans Hypothetical p... 27 8.2
U28941-8|AAC71105.2| 470|Caenorhabditis elegans Hypothetical pr... 27 8.2
AL023835-10|CAA19494.2| 691|Caenorhabditis elegans Hypothetical... 27 8.2
AB223006-1|BAE16563.1| 2862|Caenorhabditis elegans Mediator comp... 27 8.2
>U39852-7|AAK39260.1| 240|Caenorhabditis elegans Ground-like (grd
related) protein 6 protein.
Length = 240
Score = 35.9 bits (79), Expect = 0.024
Identities = 17/40 (42%), Positives = 18/40 (45%)
Frame = -1
Query: 442 PNPESWCPNPESWCPNPESWCPNPESCPKLPNPESWCPNP 323
P P CP P P P +CP P CP P P CP P
Sbjct: 48 PMPMPVCPPPP---PCPAQFCPPPPICPPPPPPPMPCPPP 84
Score = 34.3 bits (75), Expect = 0.072
Identities = 24/69 (34%), Positives = 30/69 (43%), Gaps = 2/69 (2%)
Frame = -1
Query: 514 CPA-LSLPKLSSAESPKLPNPESWCPNPESWCPNPESWCPNPESWCPNPESCPKLPNPES 338
CP + P++ A +P P CP P P P +CP P CP P P +P P
Sbjct: 30 CPTPMCQPRMPCAAPMPMPMPMPVCPPPP---PCPAQFCP-PPPICPPPPP-PPMPCPPP 84
Query: 337 WCPNPE-SC 314
P P SC
Sbjct: 85 PPPMPRPSC 93
>U40799-6|AAA81484.2| 210|Caenorhabditis elegans Ground-like (grd
related) protein 4 protein.
Length = 210
Score = 34.7 bits (76), Expect = 0.054
Identities = 22/57 (38%), Positives = 24/57 (42%), Gaps = 2/57 (3%)
Frame = -1
Query: 487 SSAESPKLPNPESWCPNPESWCPNPESWCPNPESWCPNPESC--PKLPNPESWCPNP 323
S P P P C P CP P CP P+ +CP P C P P P CP P
Sbjct: 24 SMGPPPCPPPPPPMCAPPPLPCPPPPI-CP-PQ-FCPPPPMCPPPPPPPPPPMCPPP 77
>Z78540-6|CAD30431.1| 887|Caenorhabditis elegans Hypothetical
protein C33G3.1b protein.
Length = 887
Score = 33.1 bits (72), Expect = 0.17
Identities = 25/97 (25%), Positives = 46/97 (47%), Gaps = 5/97 (5%)
Frame = -1
Query: 625 PPMAVPI---PPNEVAMPSRPFSILSSSIPWSAKLEISFTCPALS-LPKLSSAESPKLPN 458
P A+P P + + + + F+ L S +P + L P S +P++ + P +P
Sbjct: 287 PQTALPYQQKPQSLLNIQQQQFNTLPSQMPSTQTLPSLSENPGQSHIPRMMTMP-PNMPY 345
Query: 457 PESWCPNPESWCPNPESWCPNPESWCPN-PESCPKLP 350
P + P+P +W P S+ + +S N P P++P
Sbjct: 346 PTATLPHPRTWAPQIPSYPNSMQSLEQNVPMYYPQMP 382
>Z78540-5|CAB01738.2| 793|Caenorhabditis elegans Hypothetical
protein C33G3.1a protein.
Length = 793
Score = 33.1 bits (72), Expect = 0.17
Identities = 25/97 (25%), Positives = 46/97 (47%), Gaps = 5/97 (5%)
Frame = -1
Query: 625 PPMAVPI---PPNEVAMPSRPFSILSSSIPWSAKLEISFTCPALS-LPKLSSAESPKLPN 458
P A+P P + + + + F+ L S +P + L P S +P++ + P +P
Sbjct: 193 PQTALPYQQKPQSLLNIQQQQFNTLPSQMPSTQTLPSLSENPGQSHIPRMMTMP-PNMPY 251
Query: 457 PESWCPNPESWCPNPESWCPNPESWCPN-PESCPKLP 350
P + P+P +W P S+ + +S N P P++P
Sbjct: 252 PTATLPHPRTWAPQIPSYPNSMQSLEQNVPMYYPQMP 288
>Z72501-3|CAD30430.1| 887|Caenorhabditis elegans Hypothetical
protein C33G3.1b protein.
Length = 887
Score = 33.1 bits (72), Expect = 0.17
Identities = 25/97 (25%), Positives = 46/97 (47%), Gaps = 5/97 (5%)
Frame = -1
Query: 625 PPMAVPI---PPNEVAMPSRPFSILSSSIPWSAKLEISFTCPALS-LPKLSSAESPKLPN 458
P A+P P + + + + F+ L S +P + L P S +P++ + P +P
Sbjct: 287 PQTALPYQQKPQSLLNIQQQQFNTLPSQMPSTQTLPSLSENPGQSHIPRMMTMP-PNMPY 345
Query: 457 PESWCPNPESWCPNPESWCPNPESWCPN-PESCPKLP 350
P + P+P +W P S+ + +S N P P++P
Sbjct: 346 PTATLPHPRTWAPQIPSYPNSMQSLEQNVPMYYPQMP 382
>AJ133838-1|CAB44432.1| 793|Caenorhabditis elegans DYC-1 protein
protein.
Length = 793
Score = 33.1 bits (72), Expect = 0.17
Identities = 25/97 (25%), Positives = 46/97 (47%), Gaps = 5/97 (5%)
Frame = -1
Query: 625 PPMAVPI---PPNEVAMPSRPFSILSSSIPWSAKLEISFTCPALS-LPKLSSAESPKLPN 458
P A+P P + + + + F+ L S +P + L P S +P++ + P +P
Sbjct: 193 PQTALPYQQKPQSLLNIQQQQFNTLPSQMPSTQTLPSLSENPGQSHIPRMMTMP-PNMPY 251
Query: 457 PESWCPNPESWCPNPESWCPNPESWCPN-PESCPKLP 350
P + P+P +W P S+ + +S N P P++P
Sbjct: 252 PTATLPHPRTWAPQIPSYPNSMQSLEQNVPMYYPQMP 288
>Z99279-6|CAB16498.1| 640|Caenorhabditis elegans Hypothetical
protein Y57G11A.2 protein.
Length = 640
Score = 31.1 bits (67), Expect = 0.67
Identities = 16/41 (39%), Positives = 18/41 (43%), Gaps = 3/41 (7%)
Frame = -1
Query: 436 PESWCPNPESWCPNPESWCPNP---ESCPKLPNPESWCPNP 323
PE P PE P PE P P E P++P P P P
Sbjct: 517 PEDPNPIPEDTVPGPEDTTPGPAVTEEIPEVPEPTEEPPTP 557
>Z82284-8|CAB05294.1| 640|Caenorhabditis elegans Hypothetical
protein Y57G11A.2 protein.
Length = 640
Score = 31.1 bits (67), Expect = 0.67
Identities = 16/41 (39%), Positives = 18/41 (43%), Gaps = 3/41 (7%)
Frame = -1
Query: 436 PESWCPNPESWCPNPESWCPNP---ESCPKLPNPESWCPNP 323
PE P PE P PE P P E P++P P P P
Sbjct: 517 PEDPNPIPEDTVPGPEDTTPGPAVTEEIPEVPEPTEEPPTP 557
>U37429-11|AAA79352.1| 312|Caenorhabditis elegans Hypothetical
protein F09E5.12 protein.
Length = 312
Score = 29.9 bits (64), Expect = 1.5
Identities = 18/56 (32%), Positives = 26/56 (46%), Gaps = 1/56 (1%)
Frame = -1
Query: 484 SAESPKLPNPESWCPN-PESWCPNPESWCPNPESWCPNPESCPKLPNPESWCPNPE 320
+A SP L ++ P P PN + W +P + +P S P+ P P NPE
Sbjct: 239 AARSPALARQQNDLPRRPIPLPPNRDHWTGHPTLYYNSPYSFPRRPRPND-RENPE 293
>Z70309-6|CAA94360.1| 324|Caenorhabditis elegans Hypothetical
protein R102.6 protein.
Length = 324
Score = 28.7 bits (61), Expect = 3.6
Identities = 15/34 (44%), Positives = 15/34 (44%), Gaps = 1/34 (2%)
Frame = -1
Query: 421 PNPESWC-PNPESWCPNPESCPKLPNPESWCPNP 323
P P C P P CP P CP P P CP P
Sbjct: 244 PPPSPVCMPPPPPPCPMPIPCPP-PPPACSCPPP 276
>U41543-12|AAZ91345.1| 401|Caenorhabditis elegans Groundhog
(hedgehog-like family)protein 7 protein.
Length = 401
Score = 28.7 bits (61), Expect = 3.6
Identities = 27/97 (27%), Positives = 36/97 (37%), Gaps = 1/97 (1%)
Frame = -1
Query: 625 PPMAVPIPPNEVAMPSRPF-SILSSSIPWSAKLEISFTCPALSLPKLSSAESPKLPNPES 449
PP A P P + V P+ P S +++P A + A+ P P P P+
Sbjct: 67 PPPA-PYPQHAVPAPAPPLASYPQNAVPVPAPPPAPYPQHAVPAPA-----PPPAPYPQH 120
Query: 448 WCPNPESWCPNPESWCPNPESWCPNPESCPKLPNPES 338
P P + P P P P P P P P S
Sbjct: 121 AVPAPAPYQQQPPPPPPPPHYPPPPPHYPPPPPAPHS 157
>Z69884-5|CAA93747.1| 423|Caenorhabditis elegans Hypothetical
protein F31F6.7 protein.
Length = 423
Score = 28.3 bits (60), Expect = 4.7
Identities = 14/29 (48%), Positives = 21/29 (72%), Gaps = 1/29 (3%)
Frame = +3
Query: 72 FPHGSSDVDGSGEVEAVAGTLKK-GFGFG 155
F HG SD+ G G+++A++ T KK G+G G
Sbjct: 68 FVHGVSDIAG-GKMQALSATYKKHGYGSG 95
>U80448-6|AAO12417.1| 687|Caenorhabditis elegans Hypothetical
protein F59A3.2b protein.
Length = 687
Score = 28.3 bits (60), Expect = 4.7
Identities = 15/43 (34%), Positives = 23/43 (53%)
Frame = -1
Query: 511 PALSLPKLSSAESPKLPNPESWCPNPESWCPNPESWCPNPESW 383
P + P++ S+ L NP + P P S PN ++ PN ES+
Sbjct: 552 PRIPPPQIYSSPGQALFNPTNLYPTPPSSLPN--TYVPNQESF 592
>U80448-5|AAB37819.1| 975|Caenorhabditis elegans Hypothetical
protein F59A3.2a protein.
Length = 975
Score = 28.3 bits (60), Expect = 4.7
Identities = 15/43 (34%), Positives = 23/43 (53%)
Frame = -1
Query: 511 PALSLPKLSSAESPKLPNPESWCPNPESWCPNPESWCPNPESW 383
P + P++ S+ L NP + P P S PN ++ PN ES+
Sbjct: 552 PRIPPPQIYSSPGQALFNPTNLYPTPPSSLPN--TYVPNQESF 592
>U55854-1|AAA98010.2| 418|Caenorhabditis elegans Hypothetical
protein C04G6.4 protein.
Length = 418
Score = 28.3 bits (60), Expect = 4.7
Identities = 24/85 (28%), Positives = 39/85 (45%), Gaps = 2/85 (2%)
Frame = -1
Query: 625 PPMAVPIPPNEVA--MPSRPFSILSSSIPWSAKLEISFTCPALSLPKLSSAESPKLPNPE 452
PP +P PP ++ MP P +L +I ++ L+ + T K + +P P
Sbjct: 10 PPFDMPPPPKPLSFEMPKPP--VLQPNI--ASLLQKTNTTGEDVKSKDAQPSVTPVP-PP 64
Query: 451 SWCPNPESWCPNPESWCPNPESWCP 377
++ P P + P P+S PNP P
Sbjct: 65 TFNPVPNPFAPRPKSVSPNPHPDVP 89
>AF067211-1|AAC16986.1| 455|Caenorhabditis elegans Hypothetical
protein B0205.10 protein.
Length = 455
Score = 28.3 bits (60), Expect = 4.7
Identities = 17/53 (32%), Positives = 23/53 (43%)
Frame = -1
Query: 481 AESPKLPNPESWCPNPESWCPNPESWCPNPESWCPNPESCPKLPNPESWCPNP 323
A +P P+ P PE+ P PE+ P P P + P PE+ P P
Sbjct: 111 AAAPVQETPQV-APAPETPAPAPETPAPAPVQETPQVVAPAPEPTPEAAAPVP 162
Score = 27.9 bits (59), Expect = 6.2
Identities = 24/89 (26%), Positives = 36/89 (40%), Gaps = 1/89 (1%)
Frame = -1
Query: 601 PNEVAMPSRPFSILSSSIPWSAKLEISFTCPALSLPKLSSAESPKLPNPESWCPNPESWC 422
P V +P P + S P + P P+++ A P PE+ P P
Sbjct: 86 PAPVPVPE-PAQLAPQSAPEPTP-DAPAAAPVQETPQVAPAPETPAPAPETPAPAPVQ-- 141
Query: 421 PNPESWCPNPESWCPNPESCPKLP-NPES 338
P+ P PE P PE+ +P +P+S
Sbjct: 142 ETPQVVAPAPE---PTPEAAAPVPADPQS 167
>U46675-7|AAB52641.1| 1274|Caenorhabditis elegans Hypothetical protein
F35A5.1 protein.
Length = 1274
Score = 27.9 bits (59), Expect = 6.2
Identities = 32/115 (27%), Positives = 44/115 (38%), Gaps = 13/115 (11%)
Frame = -1
Query: 625 PPMAVPIPPNEVAMPSRPFS--ILSSSIPWSAKLE----ISFTCPALSLPKLS--SAESP 470
P A+PIP N P P + PW E +S P P L+ + P
Sbjct: 961 PKKAIPIPANTQEAPPTPVKNPVKKWKPPWEDDDEPAEPVSAPEPEKKTPVLAKKAPAKP 1020
Query: 469 KLPNPESWCP---NPESWCPN-PESWCPNP-ESWCPNPESCPKLPNPESWCPNPE 320
+ P+P+ P P+ P P + NP + W P E + P S P PE
Sbjct: 1021 RDPSPKKAAPVAAKPDPKIPEVPPTPVKNPVKKWKPPWEDDDEPSEPVS-APEPE 1074
>AL161712-8|CAC70133.1| 340|Caenorhabditis elegans Hypothetical
protein Y66D12A.11 protein.
Length = 340
Score = 27.9 bits (59), Expect = 6.2
Identities = 15/42 (35%), Positives = 18/42 (42%)
Frame = -1
Query: 496 PKLSSAESPKLPNPESWCPNPESWCPNPESWCPNPESWCPNP 371
P+ S SP P+P PN N + WC E CP P
Sbjct: 140 PRARSMTSPPPPHP----PNSFMSAENQKLWCKLYEQTCPPP 177
>AF016448-12|AAB65959.1| 316|Caenorhabditis elegans Hypothetical
protein F41E6.11 protein.
Length = 316
Score = 27.9 bits (59), Expect = 6.2
Identities = 25/103 (24%), Positives = 37/103 (35%), Gaps = 2/103 (1%)
Frame = -1
Query: 625 PPMAVPIPPNEVAMPSRPFSILSSSIPWSAKLEISFTCPALSLPKLSSAESPKLPNPESW 446
PP P+PP + P+ ++ + P +E P P + P P +
Sbjct: 42 PPQYAPLPPPPMPAPAPAYNPYPCANPPCIVVEPMPVAPPAPAPAYNPYPCATPPCPLPY 101
Query: 445 CPNPESWCPNPESWCPNPESW-CPNPESCPKLPNPESW-CPNP 323
P P + P P P E + C P P P E + C P
Sbjct: 102 IPEPVAPVPAP---APVYEPYACAAPPCPPPTPVYEPYACAAP 141
>AC024772-3|AAF60538.1| 2344|Caenorhabditis elegans Hypothetical
protein Y40C5A.3 protein.
Length = 2344
Score = 27.9 bits (59), Expect = 6.2
Identities = 20/59 (33%), Positives = 22/59 (37%)
Frame = -1
Query: 496 PKLSSAESPKLPNPESWCPNPESWCPNPESWCPNPESWCPNPESCPKLPNPESWCPNPE 320
P + S ESP P P NPE P S P P S P PE P P+
Sbjct: 568 PSMPSGESPAQPEPSIPAVNPEPSPSQPSS--SGPIQTAPPSPSSPN-AIPEGPPPGPD 623
>Z74031-3|CAA98455.1| 245|Caenorhabditis elegans Hypothetical
protein F32D8.3 protein.
Length = 245
Score = 27.5 bits (58), Expect = 8.2
Identities = 11/35 (31%), Positives = 15/35 (42%)
Frame = -1
Query: 460 NPESWCPNPESWCPNPESWCPNPESWCPNPESCPK 356
NP+ +C E C + N C PE CP+
Sbjct: 80 NPDPYCSKCEPGCTCRNGFVRNSLKLCVLPEECPR 114
>Z68314-9|CAA92667.2| 2862|Caenorhabditis elegans Hypothetical protein
K08F8.6 protein.
Length = 2862
Score = 27.5 bits (58), Expect = 8.2
Identities = 21/70 (30%), Positives = 30/70 (42%), Gaps = 7/70 (10%)
Frame = -1
Query: 511 PALSLPKLSSAESPKLPNPESWCP---NPESWCP-NPESWCPNPESWCPNPESCPKL--- 353
P L+ P S +SP +P P + P P S P P ++ P S+ P + P +
Sbjct: 1205 PGLTTPMASIFQSPTMPPPHTPSPFSAGPMSHHPMGPPAYPGTPGSFPPTTPTYPGMTPR 1264
Query: 352 PNPESWCPNP 323
P P P P
Sbjct: 1265 PGPNFGPPGP 1274
>Z66497-12|CAA91289.2| 2862|Caenorhabditis elegans Hypothetical
protein K08F8.6 protein.
Length = 2862
Score = 27.5 bits (58), Expect = 8.2
Identities = 21/70 (30%), Positives = 30/70 (42%), Gaps = 7/70 (10%)
Frame = -1
Query: 511 PALSLPKLSSAESPKLPNPESWCP---NPESWCP-NPESWCPNPESWCPNPESCPKL--- 353
P L+ P S +SP +P P + P P S P P ++ P S+ P + P +
Sbjct: 1205 PGLTTPMASIFQSPTMPPPHTPSPFSAGPMSHHPMGPPAYPGTPGSFPPTTPTYPGMTPR 1264
Query: 352 PNPESWCPNP 323
P P P P
Sbjct: 1265 PGPNFGPPGP 1274
>U28941-8|AAC71105.2| 470|Caenorhabditis elegans Hypothetical
protein F31D5.2 protein.
Length = 470
Score = 27.5 bits (58), Expect = 8.2
Identities = 17/44 (38%), Positives = 22/44 (50%)
Frame = +3
Query: 15 KMALKITCSILAVLAVAQAFPHGSSDVDGSGEVEAVAGTLKKGF 146
K+ + + CSI V AV AF + V E +AGTLK F
Sbjct: 176 KIFVYVFCSISVVAAVNTAFLPAPAYVPEKREAVTLAGTLKVTF 219
>AL023835-10|CAA19494.2| 691|Caenorhabditis elegans Hypothetical
protein Y37A1B.11 protein.
Length = 691
Score = 27.5 bits (58), Expect = 8.2
Identities = 17/48 (35%), Positives = 22/48 (45%)
Frame = -1
Query: 463 PNPESWCPNPESWCPNPESWCPNPESWCPNPESCPKLPNPESWCPNPE 320
P+PE + E P+PE P+P P P P+ P P P PE
Sbjct: 522 PSPEESDDDQELILPSPE---PSPVRE-PTPPPPPREPTPREPTPEPE 565
>AB223006-1|BAE16563.1| 2862|Caenorhabditis elegans Mediator complex
subunit Med13 protein.
Length = 2862
Score = 27.5 bits (58), Expect = 8.2
Identities = 21/70 (30%), Positives = 30/70 (42%), Gaps = 7/70 (10%)
Frame = -1
Query: 511 PALSLPKLSSAESPKLPNPESWCP---NPESWCP-NPESWCPNPESWCPNPESCPKL--- 353
P L+ P S +SP +P P + P P S P P ++ P S+ P + P +
Sbjct: 1205 PGLTTPMASIFQSPTMPPPHTPSPFSAGPMSHHPMGPPAYPGTPGSFPPTTPTYPGMTPR 1264
Query: 352 PNPESWCPNP 323
P P P P
Sbjct: 1265 PGPNFGPPGP 1274
Database: celegans
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 12,740,198
Number of sequences in database: 27,780
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 11,464,164
Number of Sequences: 27780
Number of extensions: 248067
Number of successful extensions: 1101
Number of sequences better than 10.0: 26
Number of HSP's better than 10.0 without gapping: 874
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 1037
length of database: 12,740,198
effective HSP length: 78
effective length of database: 10,573,358
effective search space used: 1363963182
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
- SilkBase 1999-2023 -