Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= bmmt5m10
(653 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Z84466-5|CAI42465.1| 207|Homo sapiens TIMP metallopeptidase inh... 69 1e-11
X03124-1|CAA26902.1| 207|Homo sapiens protein ( Human mRNA for ... 69 1e-11
S68252-1|AAD14009.1| 207|Homo sapiens TIMP-1 protein. 69 1e-11
M59906-1|AAA63234.1| 207|Homo sapiens collagenase inhibitor pro... 69 1e-11
M12670-1|AAA52436.1| 207|Homo sapiens CLGI protein. 69 1e-11
CR541982-1|CAG46779.1| 207|Homo sapiens TIMP1 protein. 69 1e-11
CR407638-1|CAG28566.1| 207|Homo sapiens TIMP1 protein. 69 1e-11
BC000866-1|AAH00866.1| 207|Homo sapiens TIMP metallopeptidase i... 69 1e-11
X02598-1|CAA26443.1| 207|Homo sapiens protein ( Human mRNA for ... 68 3e-11
Z98256-2|CAI20115.1| 211|Homo sapiens TIMP metallopeptidase inh... 66 8e-11
X76227-1|CAA53813.1| 211|Homo sapiens tissue inhibitor of metal... 66 8e-11
U67195-1|AAB07547.1| 211|Homo sapiens tissue inhibitor of metal... 66 8e-11
U33114-1|AAC50393.1| 211|Homo sapiens tissue inhibitor of metal... 66 8e-11
U14394-1|AAB60373.1| 211|Homo sapiens tissue inhibitor of metal... 66 8e-11
U02571-1|AAA17672.1| 211|Homo sapiens tissue inhibitor of metal... 66 8e-11
S78453-1|AAB34532.1| 211|Homo sapiens TIMP-3 protein. 66 8e-11
CR456593-1|CAG30479.1| 211|Homo sapiens TIMP3 protein. 66 8e-11
BT006848-1|AAP35494.1| 211|Homo sapiens tissue inhibitor of met... 66 8e-11
BC014277-1|AAH14277.1| 211|Homo sapiens TIMP metallopeptidase i... 66 8e-11
AL023282-2|CAI17996.1| 211|Homo sapiens TIMP metallopeptidase i... 66 8e-11
AY932824-1|AAX47478.1| 188|Homo sapiens tissue inhibitor of met... 66 1e-10
Z98256-1|CAI20114.1| 204|Homo sapiens TIMP metallopeptidase inh... 65 2e-10
AL023282-1|CAI17994.1| 204|Homo sapiens TIMP metallopeptidase i... 65 2e-10
L15078-1|AAA21815.1| 197|Homo sapiens metalloproteinase-3 tissu... 64 4e-10
Z30183-1|CAA82918.1| 210|Homo sapiens mig-5 protein. 63 7e-10
U76456-1|AAB40391.1| 224|Homo sapiens tissue inhibitor of metal... 62 2e-09
BT019627-1|AAV38433.1| 224|Homo sapiens tissue inhibitor of met... 62 2e-09
BC010553-1|AAH10553.1| 224|Homo sapiens TIMP metallopeptidase i... 62 2e-09
AF057532-1|AAC34422.1| 224|Homo sapiens tissue inhibitor of met... 62 2e-09
S48568-1|AAB19474.1| 220|Homo sapiens tissue inhibitor of metal... 59 1e-08
M32304-1|AAA59581.1| 220|Homo sapiens TIMP protein. 59 1e-08
J05593-1|AAA61186.1| 220|Homo sapiens TIMP protein. 59 1e-08
BC071586-1|AAH71586.1| 220|Homo sapiens TIMP metallopeptidase i... 59 1e-08
BC052605-1|AAH52605.1| 220|Homo sapiens TIMP metallopeptidase i... 59 1e-08
U44385-1|AAC50729.1| 218|Homo sapiens tissue inhibitor of metal... 58 3e-08
Z84466-6|CAI42466.1| 136|Homo sapiens TIMP metallopeptidase inh... 48 2e-05
D11139-1|BAA01913.1| 166|Homo sapiens tissue inhibitor of metal... 47 7e-05
U38955-1|AAB17602.1| 170|Homo sapiens tissue inhibitor of metal... 45 3e-04
X54533-1|CAA38400.1| 185|Homo sapiens Tissue inhibitor of meta... 43 8e-04
Z84466-4|CAI42464.1| 143|Homo sapiens TIMP metallopeptidase inh... 41 0.003
Z84466-7|CAI42467.1| 96|Homo sapiens TIMP metallopeptidase inh... 38 0.024
S68860-1|AAD14025.1| 50|Homo sapiens timp-2 protein. 33 0.67
L47361-1|AAA75558.1| 40|Homo sapiens tissue inhibitor of metal... 31 2.7
>Z84466-5|CAI42465.1| 207|Homo sapiens TIMP metallopeptidase
inhibitor 1 protein.
Length = 207
Score = 69.3 bits (162), Expect = 1e-11
Identities = 39/121 (32%), Positives = 59/121 (48%), Gaps = 5/121 (4%)
Frame = +3
Query: 306 ACTCALEHPQTHYCKSDFVIVGRVQKTFRGRED--YDIYKVKIRNVFKATDKAVAALRSG 479
ACTC HPQT +C SD VI + T + Y Y++K+ ++K A
Sbjct: 23 ACTCVPPHPQTAFCNSDLVIRAKFVGTPEVNQTTLYQRYEIKMTKMYKGFQALGDAADIR 82
Query: 480 RLFTPPHESLCGV---SLQPRETYVITGQVLHLEAHIYLCGYIAKWREVTPRQRKGFRLL 650
++TP ES+CG S E ++I G++ HI C ++A W ++ QR+GF
Sbjct: 83 FVYTPAMESVCGYFHRSHNRSEEFLIAGKLQDGLLHITTCSFVAPWNSLSLAQRRGFTKT 142
Query: 651 Y 653
Y
Sbjct: 143 Y 143
>X03124-1|CAA26902.1| 207|Homo sapiens protein ( Human mRNA for
tissue inhibitor of metalloproteinases (TIMP). ).
Length = 207
Score = 69.3 bits (162), Expect = 1e-11
Identities = 39/121 (32%), Positives = 59/121 (48%), Gaps = 5/121 (4%)
Frame = +3
Query: 306 ACTCALEHPQTHYCKSDFVIVGRVQKTFRGRED--YDIYKVKIRNVFKATDKAVAALRSG 479
ACTC HPQT +C SD VI + T + Y Y++K+ ++K A
Sbjct: 23 ACTCVPPHPQTAFCNSDLVIRAKFVGTPEVNQTTLYQRYEIKMTKMYKGFQALGDAADIR 82
Query: 480 RLFTPPHESLCGV---SLQPRETYVITGQVLHLEAHIYLCGYIAKWREVTPRQRKGFRLL 650
++TP ES+CG S E ++I G++ HI C ++A W ++ QR+GF
Sbjct: 83 FVYTPAMESVCGYFHRSHNRSEEFLIAGKLQDGLLHITTCSFVAPWNSLSLAQRRGFTKT 142
Query: 651 Y 653
Y
Sbjct: 143 Y 143
>S68252-1|AAD14009.1| 207|Homo sapiens TIMP-1 protein.
Length = 207
Score = 69.3 bits (162), Expect = 1e-11
Identities = 39/121 (32%), Positives = 59/121 (48%), Gaps = 5/121 (4%)
Frame = +3
Query: 306 ACTCALEHPQTHYCKSDFVIVGRVQKTFRGRED--YDIYKVKIRNVFKATDKAVAALRSG 479
ACTC HPQT +C SD VI + T + Y Y++K+ ++K A
Sbjct: 23 ACTCVPPHPQTAFCNSDLVIRAKFVGTPEVNQTTLYQRYEIKMTKMYKGFQALGDAADIR 82
Query: 480 RLFTPPHESLCGV---SLQPRETYVITGQVLHLEAHIYLCGYIAKWREVTPRQRKGFRLL 650
++TP ES+CG S E ++I G++ HI C ++A W ++ QR+GF
Sbjct: 83 FVYTPAMESVCGYFHRSHNRSEEFLIAGKLQDGLLHITTCSFVAPWNSLSLAQRRGFTKT 142
Query: 651 Y 653
Y
Sbjct: 143 Y 143
>M59906-1|AAA63234.1| 207|Homo sapiens collagenase inhibitor
protein.
Length = 207
Score = 69.3 bits (162), Expect = 1e-11
Identities = 39/121 (32%), Positives = 59/121 (48%), Gaps = 5/121 (4%)
Frame = +3
Query: 306 ACTCALEHPQTHYCKSDFVIVGRVQKTFRGRED--YDIYKVKIRNVFKATDKAVAALRSG 479
ACTC HPQT +C SD VI + T + Y Y++K+ ++K A
Sbjct: 23 ACTCVPPHPQTAFCNSDLVIRAKFVGTPEVNQTTLYQRYEIKMTKMYKGFQALGDAADIR 82
Query: 480 RLFTPPHESLCGV---SLQPRETYVITGQVLHLEAHIYLCGYIAKWREVTPRQRKGFRLL 650
++TP ES+CG S E ++I G++ HI C ++A W ++ QR+GF
Sbjct: 83 FVYTPAMESVCGYFHRSHNRSEEFLIAGKLQDGLLHITTCSFVAPWNSLSLAQRRGFTKT 142
Query: 651 Y 653
Y
Sbjct: 143 Y 143
>M12670-1|AAA52436.1| 207|Homo sapiens CLGI protein.
Length = 207
Score = 69.3 bits (162), Expect = 1e-11
Identities = 39/121 (32%), Positives = 59/121 (48%), Gaps = 5/121 (4%)
Frame = +3
Query: 306 ACTCALEHPQTHYCKSDFVIVGRVQKTFRGRED--YDIYKVKIRNVFKATDKAVAALRSG 479
ACTC HPQT +C SD VI + T + Y Y++K+ ++K A
Sbjct: 23 ACTCVPPHPQTAFCNSDLVIRAKFVGTPEVNQTTLYQRYEIKMTKMYKGFQALGDAADIR 82
Query: 480 RLFTPPHESLCGV---SLQPRETYVITGQVLHLEAHIYLCGYIAKWREVTPRQRKGFRLL 650
++TP ES+CG S E ++I G++ HI C ++A W ++ QR+GF
Sbjct: 83 FVYTPAMESVCGYFHRSHNRSEEFLIAGKLQDGLLHITTCSFVAPWNSLSLAQRRGFTKT 142
Query: 651 Y 653
Y
Sbjct: 143 Y 143
>CR541982-1|CAG46779.1| 207|Homo sapiens TIMP1 protein.
Length = 207
Score = 69.3 bits (162), Expect = 1e-11
Identities = 39/121 (32%), Positives = 59/121 (48%), Gaps = 5/121 (4%)
Frame = +3
Query: 306 ACTCALEHPQTHYCKSDFVIVGRVQKTFRGRED--YDIYKVKIRNVFKATDKAVAALRSG 479
ACTC HPQT +C SD VI + T + Y Y++K+ ++K A
Sbjct: 23 ACTCVPPHPQTAFCNSDLVIRAKFVGTPEVNQTTLYQRYEIKMTKMYKGFQALGDAADIR 82
Query: 480 RLFTPPHESLCGV---SLQPRETYVITGQVLHLEAHIYLCGYIAKWREVTPRQRKGFRLL 650
++TP ES+CG S E ++I G++ HI C ++A W ++ QR+GF
Sbjct: 83 FVYTPAMESVCGYFHRSHNRSEEFLIAGKLQDGLLHITTCSFVAPWNSLSLAQRRGFTKT 142
Query: 651 Y 653
Y
Sbjct: 143 Y 143
>CR407638-1|CAG28566.1| 207|Homo sapiens TIMP1 protein.
Length = 207
Score = 69.3 bits (162), Expect = 1e-11
Identities = 39/121 (32%), Positives = 59/121 (48%), Gaps = 5/121 (4%)
Frame = +3
Query: 306 ACTCALEHPQTHYCKSDFVIVGRVQKTFRGRED--YDIYKVKIRNVFKATDKAVAALRSG 479
ACTC HPQT +C SD VI + T + Y Y++K+ ++K A
Sbjct: 23 ACTCVPPHPQTAFCNSDLVIRAKFVGTPEVNQTTLYQRYEIKMTKMYKGFQALGDAADIR 82
Query: 480 RLFTPPHESLCGV---SLQPRETYVITGQVLHLEAHIYLCGYIAKWREVTPRQRKGFRLL 650
++TP ES+CG S E ++I G++ HI C ++A W ++ QR+GF
Sbjct: 83 FVYTPAMESVCGYFHRSHNRSEEFLIAGKLQDGLLHITTCSFVAPWNSLSLAQRRGFTKT 142
Query: 651 Y 653
Y
Sbjct: 143 Y 143
>BC000866-1|AAH00866.1| 207|Homo sapiens TIMP metallopeptidase
inhibitor 1 protein.
Length = 207
Score = 69.3 bits (162), Expect = 1e-11
Identities = 39/121 (32%), Positives = 59/121 (48%), Gaps = 5/121 (4%)
Frame = +3
Query: 306 ACTCALEHPQTHYCKSDFVIVGRVQKTFRGRED--YDIYKVKIRNVFKATDKAVAALRSG 479
ACTC HPQT +C SD VI + T + Y Y++K+ ++K A
Sbjct: 23 ACTCVPPHPQTAFCNSDLVIRAKFVGTPEVNQTTLYQRYEIKMTKMYKGFQALGDAADIR 82
Query: 480 RLFTPPHESLCGV---SLQPRETYVITGQVLHLEAHIYLCGYIAKWREVTPRQRKGFRLL 650
++TP ES+CG S E ++I G++ HI C ++A W ++ QR+GF
Sbjct: 83 FVYTPAMESVCGYFHRSHNRSEEFLIAGKLQDGLLHITTCSFVAPWNSLSLAQRRGFTKT 142
Query: 651 Y 653
Y
Sbjct: 143 Y 143
>X02598-1|CAA26443.1| 207|Homo sapiens protein ( Human mRNA for EPA
glycoprotein (erythroid-potentiating activity). ).
Length = 207
Score = 67.7 bits (158), Expect = 3e-11
Identities = 38/120 (31%), Positives = 58/120 (48%), Gaps = 5/120 (4%)
Frame = +3
Query: 309 CTCALEHPQTHYCKSDFVIVGRVQKTFRGRED--YDIYKVKIRNVFKATDKAVAALRSGR 482
CTC HPQT +C SD VI + T + Y Y++K+ ++K A
Sbjct: 24 CTCVPPHPQTAFCNSDLVIRAKFVGTPEVNQTTLYQRYEIKMTKMYKGFQALGDAADIRF 83
Query: 483 LFTPPHESLCGV---SLQPRETYVITGQVLHLEAHIYLCGYIAKWREVTPRQRKGFRLLY 653
++TP ES+CG S E ++I G++ HI C ++A W ++ QR+GF Y
Sbjct: 84 VYTPAMESVCGYFHRSHNRSEEFLIAGKLQDGLLHITTCSFVAPWNSLSLAQRRGFTKTY 143
>Z98256-2|CAI20115.1| 211|Homo sapiens TIMP metallopeptidase
inhibitor 3 (Sorsby fundus dystrophy,
pseudoinflammatory) protein.
Length = 211
Score = 66.5 bits (155), Expect = 8e-11
Identities = 43/139 (30%), Positives = 70/139 (50%), Gaps = 8/139 (5%)
Frame = +3
Query: 261 WLTLALVAASCRV----ASACTCALEHPQTHYCKSDFVIVGRV--QKTFR-GREDYDIYK 419
WL L ++ S + A ACTC+ HPQ +C SD VI +V +K + G +Y
Sbjct: 4 WLGLIVLLGSWSLGDWGAEACTCSPSHPQDAFCNSDIVIRAKVVGKKLVKEGPFGTLVYT 63
Query: 420 VKIRNVFKATDKAVAALRSGRLFTPPHESLCGVSLQPRE-TYVITGQVLHLEAHIYLCGY 596
+K +++ K + T ESLCG+ L+ + Y++TG+V + + LC +
Sbjct: 64 IKQMKMYRGFTKMP---HVQYIHTEASESLCGLKLEVNKYQYLLTGRVYDGKMYTGLCNF 120
Query: 597 IAKWREVTPRQRKGFRLLY 653
+ +W ++T QRKG Y
Sbjct: 121 VERWDQLTLSQRKGLNYRY 139
>X76227-1|CAA53813.1| 211|Homo sapiens tissue inhibitor of
metalloproteinases-3 protein.
Length = 211
Score = 66.5 bits (155), Expect = 8e-11
Identities = 43/139 (30%), Positives = 70/139 (50%), Gaps = 8/139 (5%)
Frame = +3
Query: 261 WLTLALVAASCRV----ASACTCALEHPQTHYCKSDFVIVGRV--QKTFR-GREDYDIYK 419
WL L ++ S + A ACTC+ HPQ +C SD VI +V +K + G +Y
Sbjct: 4 WLGLIVLLGSWSLGDWGAEACTCSPSHPQDAFCNSDIVIRAKVVGKKLVKEGPFGTLVYT 63
Query: 420 VKIRNVFKATDKAVAALRSGRLFTPPHESLCGVSLQPRE-TYVITGQVLHLEAHIYLCGY 596
+K +++ K + T ESLCG+ L+ + Y++TG+V + + LC +
Sbjct: 64 IKQMKMYRGFTKMP---HVQYIHTEASESLCGLKLEVNKYQYLLTGRVYDGKMYTGLCNF 120
Query: 597 IAKWREVTPRQRKGFRLLY 653
+ +W ++T QRKG Y
Sbjct: 121 VERWDQLTLSQRKGLNYRY 139
>U67195-1|AAB07547.1| 211|Homo sapiens tissue inhibitor of
metalloproteinase-3 protein.
Length = 211
Score = 66.5 bits (155), Expect = 8e-11
Identities = 43/139 (30%), Positives = 70/139 (50%), Gaps = 8/139 (5%)
Frame = +3
Query: 261 WLTLALVAASCRV----ASACTCALEHPQTHYCKSDFVIVGRV--QKTFR-GREDYDIYK 419
WL L ++ S + A ACTC+ HPQ +C SD VI +V +K + G +Y
Sbjct: 4 WLGLIVLLGSWSLGDWGAEACTCSPSHPQDAFCNSDIVIRAKVVGKKLVKEGPFGTLVYT 63
Query: 420 VKIRNVFKATDKAVAALRSGRLFTPPHESLCGVSLQPRE-TYVITGQVLHLEAHIYLCGY 596
+K +++ K + T ESLCG+ L+ + Y++TG+V + + LC +
Sbjct: 64 IKQMKMYRGFTKMP---HVQYIHTEASESLCGLKLEVNKYQYLLTGRVYDGKMYTGLCNF 120
Query: 597 IAKWREVTPRQRKGFRLLY 653
+ +W ++T QRKG Y
Sbjct: 121 VERWDQLTLSQRKGLNYRY 139
>U33114-1|AAC50393.1| 211|Homo sapiens tissue inhibitor of
metalloproteinases-3 protein.
Length = 211
Score = 66.5 bits (155), Expect = 8e-11
Identities = 43/139 (30%), Positives = 70/139 (50%), Gaps = 8/139 (5%)
Frame = +3
Query: 261 WLTLALVAASCRV----ASACTCALEHPQTHYCKSDFVIVGRV--QKTFR-GREDYDIYK 419
WL L ++ S + A ACTC+ HPQ +C SD VI +V +K + G +Y
Sbjct: 4 WLGLIVLLGSWSLGDWGAEACTCSPSHPQDAFCNSDIVIRAKVVGKKLVKEGPFGTLVYT 63
Query: 420 VKIRNVFKATDKAVAALRSGRLFTPPHESLCGVSLQPRE-TYVITGQVLHLEAHIYLCGY 596
+K +++ K + T ESLCG+ L+ + Y++TG+V + + LC +
Sbjct: 64 IKQMKMYRGFTKMP---HVQYIHTEASESLCGLKLEVNKYQYLLTGRVYDGKMYTGLCNF 120
Query: 597 IAKWREVTPRQRKGFRLLY 653
+ +W ++T QRKG Y
Sbjct: 121 VERWDQLTLSQRKGLNYRY 139
>U14394-1|AAB60373.1| 211|Homo sapiens tissue inhibitor of
metalloproteinases-3 protein.
Length = 211
Score = 66.5 bits (155), Expect = 8e-11
Identities = 43/139 (30%), Positives = 70/139 (50%), Gaps = 8/139 (5%)
Frame = +3
Query: 261 WLTLALVAASCRV----ASACTCALEHPQTHYCKSDFVIVGRV--QKTFR-GREDYDIYK 419
WL L ++ S + A ACTC+ HPQ +C SD VI +V +K + G +Y
Sbjct: 4 WLGLIVLLGSWSLGDWGAEACTCSPSHPQDAFCNSDIVIRAKVVGKKLVKEGPFGTLVYT 63
Query: 420 VKIRNVFKATDKAVAALRSGRLFTPPHESLCGVSLQPRE-TYVITGQVLHLEAHIYLCGY 596
+K +++ K + T ESLCG+ L+ + Y++TG+V + + LC +
Sbjct: 64 IKQMKMYRGFTKMP---HVQYIHTEASESLCGLKLEVNKYQYLLTGRVYDGKMYTGLCNF 120
Query: 597 IAKWREVTPRQRKGFRLLY 653
+ +W ++T QRKG Y
Sbjct: 121 VERWDQLTLSQRKGLNYRY 139
>U02571-1|AAA17672.1| 211|Homo sapiens tissue inhibitor of
metalloproteinase-3 precursor protein.
Length = 211
Score = 66.5 bits (155), Expect = 8e-11
Identities = 43/139 (30%), Positives = 70/139 (50%), Gaps = 8/139 (5%)
Frame = +3
Query: 261 WLTLALVAASCRV----ASACTCALEHPQTHYCKSDFVIVGRV--QKTFR-GREDYDIYK 419
WL L ++ S + A ACTC+ HPQ +C SD VI +V +K + G +Y
Sbjct: 4 WLGLIVLLGSWSLGDWGAEACTCSPSHPQDAFCNSDIVIRAKVVGKKLVKEGPFGTLVYT 63
Query: 420 VKIRNVFKATDKAVAALRSGRLFTPPHESLCGVSLQPRE-TYVITGQVLHLEAHIYLCGY 596
+K +++ K + T ESLCG+ L+ + Y++TG+V + + LC +
Sbjct: 64 IKQMKMYRGFTKMP---HVQYIHTEASESLCGLKLEVNKYQYLLTGRVYDGKMYTGLCNF 120
Query: 597 IAKWREVTPRQRKGFRLLY 653
+ +W ++T QRKG Y
Sbjct: 121 VERWDQLTLSQRKGLNYRY 139
>S78453-1|AAB34532.1| 211|Homo sapiens TIMP-3 protein.
Length = 211
Score = 66.5 bits (155), Expect = 8e-11
Identities = 43/139 (30%), Positives = 70/139 (50%), Gaps = 8/139 (5%)
Frame = +3
Query: 261 WLTLALVAASCRV----ASACTCALEHPQTHYCKSDFVIVGRV--QKTFR-GREDYDIYK 419
WL L ++ S + A ACTC+ HPQ +C SD VI +V +K + G +Y
Sbjct: 4 WLGLIVLLGSWSLGDWGAEACTCSPSHPQDAFCNSDIVIRAKVVGKKLVKEGPFGTLVYT 63
Query: 420 VKIRNVFKATDKAVAALRSGRLFTPPHESLCGVSLQPRE-TYVITGQVLHLEAHIYLCGY 596
+K +++ K + T ESLCG+ L+ + Y++TG+V + + LC +
Sbjct: 64 IKQMKMYRGFTKMP---HVQYIHTEASESLCGLKLEVNKYQYLLTGRVYDGKMYTGLCNF 120
Query: 597 IAKWREVTPRQRKGFRLLY 653
+ +W ++T QRKG Y
Sbjct: 121 VERWDQLTLSQRKGLNYRY 139
>CR456593-1|CAG30479.1| 211|Homo sapiens TIMP3 protein.
Length = 211
Score = 66.5 bits (155), Expect = 8e-11
Identities = 43/139 (30%), Positives = 70/139 (50%), Gaps = 8/139 (5%)
Frame = +3
Query: 261 WLTLALVAASCRV----ASACTCALEHPQTHYCKSDFVIVGRV--QKTFR-GREDYDIYK 419
WL L ++ S + A ACTC+ HPQ +C SD VI +V +K + G +Y
Sbjct: 4 WLGLIVLLGSWSLGDWGAEACTCSPSHPQDAFCNSDIVIRAKVVGKKLVKEGPFGTLVYT 63
Query: 420 VKIRNVFKATDKAVAALRSGRLFTPPHESLCGVSLQPRE-TYVITGQVLHLEAHIYLCGY 596
+K +++ K + T ESLCG+ L+ + Y++TG+V + + LC +
Sbjct: 64 IKQMKMYRGFTKMP---HVQYIHTEASESLCGLKLEVNKYQYLLTGRVYDGKMYTGLCNF 120
Query: 597 IAKWREVTPRQRKGFRLLY 653
+ +W ++T QRKG Y
Sbjct: 121 VERWDQLTLSQRKGLNYRY 139
>BT006848-1|AAP35494.1| 211|Homo sapiens tissue inhibitor of
metalloproteinase 3 (Sorsby fundus dystrophy,
pseudoinflamm protein.
Length = 211
Score = 66.5 bits (155), Expect = 8e-11
Identities = 43/139 (30%), Positives = 70/139 (50%), Gaps = 8/139 (5%)
Frame = +3
Query: 261 WLTLALVAASCRV----ASACTCALEHPQTHYCKSDFVIVGRV--QKTFR-GREDYDIYK 419
WL L ++ S + A ACTC+ HPQ +C SD VI +V +K + G +Y
Sbjct: 4 WLGLIVLLGSWSLGDWGAEACTCSPSHPQDAFCNSDIVIRAKVVGKKLVKEGPFGTLVYT 63
Query: 420 VKIRNVFKATDKAVAALRSGRLFTPPHESLCGVSLQPRE-TYVITGQVLHLEAHIYLCGY 596
+K +++ K + T ESLCG+ L+ + Y++TG+V + + LC +
Sbjct: 64 IKQMKMYRGFTKMP---HVQYIHTEASESLCGLKLEVNKYQYLLTGRVYDGKMYTGLCNF 120
Query: 597 IAKWREVTPRQRKGFRLLY 653
+ +W ++T QRKG Y
Sbjct: 121 VERWDQLTLSQRKGLNYRY 139
>BC014277-1|AAH14277.1| 211|Homo sapiens TIMP metallopeptidase
inhibitor 3 (Sorsby fundus dystrophy,
pseudoinflammatory) protein.
Length = 211
Score = 66.5 bits (155), Expect = 8e-11
Identities = 43/139 (30%), Positives = 70/139 (50%), Gaps = 8/139 (5%)
Frame = +3
Query: 261 WLTLALVAASCRV----ASACTCALEHPQTHYCKSDFVIVGRV--QKTFR-GREDYDIYK 419
WL L ++ S + A ACTC+ HPQ +C SD VI +V +K + G +Y
Sbjct: 4 WLGLIVLLGSWSLGDWGAEACTCSPSHPQDAFCNSDIVIRAKVVGKKLVKEGPFGTLVYT 63
Query: 420 VKIRNVFKATDKAVAALRSGRLFTPPHESLCGVSLQPRE-TYVITGQVLHLEAHIYLCGY 596
+K +++ K + T ESLCG+ L+ + Y++TG+V + + LC +
Sbjct: 64 IKQMKMYRGFTKMP---HVQYIHTEASESLCGLKLEVNKYQYLLTGRVYDGKMYTGLCNF 120
Query: 597 IAKWREVTPRQRKGFRLLY 653
+ +W ++T QRKG Y
Sbjct: 121 VERWDQLTLSQRKGLNYRY 139
>AL023282-2|CAI17996.1| 211|Homo sapiens TIMP metallopeptidase
inhibitor 3 (Sorsby fundus dystrophy,
pseudoinflammatory) protein.
Length = 211
Score = 66.5 bits (155), Expect = 8e-11
Identities = 43/139 (30%), Positives = 70/139 (50%), Gaps = 8/139 (5%)
Frame = +3
Query: 261 WLTLALVAASCRV----ASACTCALEHPQTHYCKSDFVIVGRV--QKTFR-GREDYDIYK 419
WL L ++ S + A ACTC+ HPQ +C SD VI +V +K + G +Y
Sbjct: 4 WLGLIVLLGSWSLGDWGAEACTCSPSHPQDAFCNSDIVIRAKVVGKKLVKEGPFGTLVYT 63
Query: 420 VKIRNVFKATDKAVAALRSGRLFTPPHESLCGVSLQPRE-TYVITGQVLHLEAHIYLCGY 596
+K +++ K + T ESLCG+ L+ + Y++TG+V + + LC +
Sbjct: 64 IKQMKMYRGFTKMP---HVQYIHTEASESLCGLKLEVNKYQYLLTGRVYDGKMYTGLCNF 120
Query: 597 IAKWREVTPRQRKGFRLLY 653
+ +W ++T QRKG Y
Sbjct: 121 VERWDQLTLSQRKGLNYRY 139
>AY932824-1|AAX47478.1| 188|Homo sapiens tissue inhibitor of
metalloproteinase 1 protein.
Length = 188
Score = 66.1 bits (154), Expect = 1e-10
Identities = 42/121 (34%), Positives = 61/121 (50%), Gaps = 5/121 (4%)
Frame = +3
Query: 306 ACTCALEHPQTHYCKSDFVIVGRVQKTFRGRED--YDIYKVKIRNVFKATDKAVAALRSG 479
ACTC HPQT +C SD VI + T + Y Y+ K+ F+A A A +R
Sbjct: 23 ACTCVPPHPQTAFCNSDLVIRAKFVGTPEVNQTTLYQRYESKMYKGFQALGDA-ADIRF- 80
Query: 480 RLFTPPHESLCGV---SLQPRETYVITGQVLHLEAHIYLCGYIAKWREVTPRQRKGFRLL 650
++TP ES+CG S E ++I G++ HI C ++A W ++ QR+GF
Sbjct: 81 -VYTPAMESVCGYFHRSHNRSEEFLIAGKLQDGLLHITTCSFVAPWNSLSLAQRRGFTKT 139
Query: 651 Y 653
Y
Sbjct: 140 Y 140
>Z98256-1|CAI20114.1| 204|Homo sapiens TIMP metallopeptidase
inhibitor 3 (Sorsby fundus dystrophy,
pseudoinflammatory) protein.
Length = 204
Score = 64.9 bits (151), Expect = 2e-10
Identities = 42/134 (31%), Positives = 69/134 (51%), Gaps = 8/134 (5%)
Frame = +3
Query: 261 WLTLALVAASCRV----ASACTCALEHPQTHYCKSDFVIVGRV--QKTFR-GREDYDIYK 419
WL L ++ S + A ACTC+ HPQ +C SD VI +V +K + G +Y
Sbjct: 4 WLGLIVLLGSWSLGDWGAEACTCSPSHPQDAFCNSDIVIRAKVVGKKLVKEGPFGTLVYT 63
Query: 420 VKIRNVFKATDKAVAALRSGRLFTPPHESLCGVSLQPRE-TYVITGQVLHLEAHIYLCGY 596
+K +++ K + T ESLCG+ L+ + Y++TG+V + + LC +
Sbjct: 64 IKQMKMYRGFTKMP---HVQYIHTEASESLCGLKLEVNKYQYLLTGRVYDGKMYTGLCNF 120
Query: 597 IAKWREVTPRQRKG 638
+ +W ++T QRKG
Sbjct: 121 VERWDQLTLSQRKG 134
>AL023282-1|CAI17994.1| 204|Homo sapiens TIMP metallopeptidase
inhibitor 3 (Sorsby fundus dystrophy,
pseudoinflammatory) protein.
Length = 204
Score = 64.9 bits (151), Expect = 2e-10
Identities = 42/134 (31%), Positives = 69/134 (51%), Gaps = 8/134 (5%)
Frame = +3
Query: 261 WLTLALVAASCRV----ASACTCALEHPQTHYCKSDFVIVGRV--QKTFR-GREDYDIYK 419
WL L ++ S + A ACTC+ HPQ +C SD VI +V +K + G +Y
Sbjct: 4 WLGLIVLLGSWSLGDWGAEACTCSPSHPQDAFCNSDIVIRAKVVGKKLVKEGPFGTLVYT 63
Query: 420 VKIRNVFKATDKAVAALRSGRLFTPPHESLCGVSLQPRE-TYVITGQVLHLEAHIYLCGY 596
+K +++ K + T ESLCG+ L+ + Y++TG+V + + LC +
Sbjct: 64 IKQMKMYRGFTKMP---HVQYIHTEASESLCGLKLEVNKYQYLLTGRVYDGKMYTGLCNF 120
Query: 597 IAKWREVTPRQRKG 638
+ +W ++T QRKG
Sbjct: 121 VERWDQLTLSQRKG 134
>L15078-1|AAA21815.1| 197|Homo sapiens metalloproteinase-3 tissue
inhibitor protein.
Length = 197
Score = 64.1 bits (149), Expect = 4e-10
Identities = 38/120 (31%), Positives = 62/120 (51%), Gaps = 4/120 (3%)
Frame = +3
Query: 306 ACTCALEHPQTHYCKSDFVIVGRV--QKTFR-GREDYDIYKVKIRNVFKATDKAVAALRS 476
ACTC+ HPQ +C SD VI +V +K + G +Y +K +++ K
Sbjct: 9 ACTCSPSHPQDAFCNSDIVIRAKVVGKKLVKEGPFGTLVYTIKQMKMYRGFTKMPHVQY- 67
Query: 477 GRLFTPPHESLCGVSLQPRE-TYVITGQVLHLEAHIYLCGYIAKWREVTPRQRKGFRLLY 653
+ T ESLCG+ L+ + Y++TG+V + + LC ++ +W ++T QRKG Y
Sbjct: 68 --IHTEASESLCGLKLEVNKYQYLLTGRVYDGKMYTGLCNFVERWDQLTLSQRKGLNYRY 125
>Z30183-1|CAA82918.1| 210|Homo sapiens mig-5 protein.
Length = 210
Score = 63.3 bits (147), Expect = 7e-10
Identities = 38/122 (31%), Positives = 62/122 (50%), Gaps = 4/122 (3%)
Frame = +3
Query: 300 ASACTCALEHPQTHYCKSDFVIVGRV--QKTFR-GREDYDIYKVKIRNVFKATDKAVAAL 470
A CTC+ HPQ +C SD VI +V +K + G +Y +K +++ K
Sbjct: 20 APRCTCSPSHPQDAFCNSDIVIRAKVVGKKLVKEGPFGTLVYTIKQMKMYRGFTKMPHVQ 79
Query: 471 RSGRLFTPPHESLCGVSLQPRE-TYVITGQVLHLEAHIYLCGYIAKWREVTPRQRKGFRL 647
+ T ESLCG+ L+ + Y++TG+V + + LC ++ +W ++T QRKG
Sbjct: 80 Y---IHTEASESLCGLKLEVNKYQYLLTGRVYDGKMYTGLCNFVERWDQLTLSQRKGLNY 136
Query: 648 LY 653
Y
Sbjct: 137 RY 138
>U76456-1|AAB40391.1| 224|Homo sapiens tissue inhibitor of
metalloproteinase 4 protein.
Length = 224
Score = 62.1 bits (144), Expect = 2e-09
Identities = 47/145 (32%), Positives = 71/145 (48%), Gaps = 14/145 (9%)
Frame = +3
Query: 261 WLTLALVAASCR---VASACTCALEHPQTHYCKSDFVIVGRV--QKTFRGRED-YDI--- 413
W+ L + A R + AC+CA HPQ H C S VI ++ +K D D
Sbjct: 11 WVLLLRLLALLRPPGLGEACSCAPAHPQQHICHSALVIRAKISSEKVVPASADPADTEKM 70
Query: 414 --YKVKIRNVFKATDKAVAALRSGRLFTPPHESLCGVSLQ--PRETYVITGQVL-HLEAH 578
Y++K +FK +K ++TP SLCGV L+ ++ Y++TGQVL +
Sbjct: 71 LRYEIKQIKMFKGFEKVKDV---QYIYTPFDSSLCGVKLEANSQKQYLLTGQVLSDGKVF 127
Query: 579 IYLCGYIAKWREVTPRQRKGFRLLY 653
I+LC YI W +++ QR+ Y
Sbjct: 128 IHLCNYIEPWEDLSLVQRESLNHHY 152
>BT019627-1|AAV38433.1| 224|Homo sapiens tissue inhibitor of
metalloproteinase 4 protein.
Length = 224
Score = 62.1 bits (144), Expect = 2e-09
Identities = 47/145 (32%), Positives = 71/145 (48%), Gaps = 14/145 (9%)
Frame = +3
Query: 261 WLTLALVAASCR---VASACTCALEHPQTHYCKSDFVIVGRV--QKTFRGRED-YDI--- 413
W+ L + A R + AC+CA HPQ H C S VI ++ +K D D
Sbjct: 11 WVLLLRLLALLRPPGLGEACSCAPAHPQQHICHSALVIRAKISSEKVVPASADPADTEKM 70
Query: 414 --YKVKIRNVFKATDKAVAALRSGRLFTPPHESLCGVSLQ--PRETYVITGQVL-HLEAH 578
Y++K +FK +K ++TP SLCGV L+ ++ Y++TGQVL +
Sbjct: 71 LRYEIKQIKMFKGFEKVKDV---QYIYTPFDSSLCGVKLEANSQKQYLLTGQVLSDGKVF 127
Query: 579 IYLCGYIAKWREVTPRQRKGFRLLY 653
I+LC YI W +++ QR+ Y
Sbjct: 128 IHLCNYIEPWEDLSLVQRESLNHHY 152
>BC010553-1|AAH10553.1| 224|Homo sapiens TIMP metallopeptidase
inhibitor 4 protein.
Length = 224
Score = 62.1 bits (144), Expect = 2e-09
Identities = 47/145 (32%), Positives = 71/145 (48%), Gaps = 14/145 (9%)
Frame = +3
Query: 261 WLTLALVAASCR---VASACTCALEHPQTHYCKSDFVIVGRV--QKTFRGRED-YDI--- 413
W+ L + A R + AC+CA HPQ H C S VI ++ +K D D
Sbjct: 11 WVLLLRLLALLRPPGLGEACSCAPAHPQQHICHSALVIRAKISSEKVVPASADPADTEKM 70
Query: 414 --YKVKIRNVFKATDKAVAALRSGRLFTPPHESLCGVSLQ--PRETYVITGQVL-HLEAH 578
Y++K +FK +K ++TP SLCGV L+ ++ Y++TGQVL +
Sbjct: 71 LRYEIKQIKMFKGFEKVKDV---QYIYTPFDSSLCGVKLEANSQKQYLLTGQVLSDGKVF 127
Query: 579 IYLCGYIAKWREVTPRQRKGFRLLY 653
I+LC YI W +++ QR+ Y
Sbjct: 128 IHLCNYIEPWEDLSLVQRESLNHHY 152
>AF057532-1|AAC34422.1| 224|Homo sapiens tissue inhibitor of
metalloproteinase 4 protein.
Length = 224
Score = 62.1 bits (144), Expect = 2e-09
Identities = 47/145 (32%), Positives = 71/145 (48%), Gaps = 14/145 (9%)
Frame = +3
Query: 261 WLTLALVAASCR---VASACTCALEHPQTHYCKSDFVIVGRV--QKTFRGRED-YDI--- 413
W+ L + A R + AC+CA HPQ H C S VI ++ +K D D
Sbjct: 11 WVLLLRLLALLRPPGLGEACSCAPAHPQQHICHSALVIRAKISSEKVVPASADPADTEKM 70
Query: 414 --YKVKIRNVFKATDKAVAALRSGRLFTPPHESLCGVSLQ--PRETYVITGQVL-HLEAH 578
Y++K +FK +K ++TP SLCGV L+ ++ Y++TGQVL +
Sbjct: 71 LRYEIKQIKMFKGFEKVKDV---QYIYTPFDSSLCGVKLEANSQKQYLLTGQVLSDGKVF 127
Query: 579 IYLCGYIAKWREVTPRQRKGFRLLY 653
I+LC YI W +++ QR+ Y
Sbjct: 128 IHLCNYIEPWEDLSLVQRESLNHHY 152
>S48568-1|AAB19474.1| 220|Homo sapiens tissue inhibitor of
metalloproteinase 2 protein.
Length = 220
Score = 59.3 bits (137), Expect = 1e-08
Identities = 42/142 (29%), Positives = 69/142 (48%), Gaps = 12/142 (8%)
Frame = +3
Query: 264 LTLALVAASCRVASACTCALEHPQTHYCKSDFVIVGRV---QKTFRGREDYD------IY 416
L L L+A R A AC+C+ HPQ +C +D VI + ++ G + Y Y
Sbjct: 12 LGLLLLATLLRPADACSCSPVHPQQAFCNADVVIRAKAVSEKEVDSGNDIYGNPIKRIQY 71
Query: 417 KVKIRNVFKATDKAVAALRSGRLFTPPHESLCGVSLQ--PRETYVITGQVL-HLEAHIYL 587
++K +FK +K + ++T P ++CGVSL ++ Y+I G+ + HI L
Sbjct: 72 EIKQIKMFKGPEKDIEF-----IYTAPSSAVCGVSLDVGGKKEYLIAGKAEGDGKMHITL 126
Query: 588 CGYIAKWREVTPRQRKGFRLLY 653
C +I W ++ Q+K Y
Sbjct: 127 CDFIVPWDTLSTTQKKSLNHRY 148
>M32304-1|AAA59581.1| 220|Homo sapiens TIMP protein.
Length = 220
Score = 59.3 bits (137), Expect = 1e-08
Identities = 42/142 (29%), Positives = 69/142 (48%), Gaps = 12/142 (8%)
Frame = +3
Query: 264 LTLALVAASCRVASACTCALEHPQTHYCKSDFVIVGRV---QKTFRGREDYD------IY 416
L L L+A R A AC+C+ HPQ +C +D VI + ++ G + Y Y
Sbjct: 12 LGLLLLATLLRPADACSCSPVHPQQAFCNADVVIRAKAVSEKEVDSGNDIYGNPIKRIQY 71
Query: 417 KVKIRNVFKATDKAVAALRSGRLFTPPHESLCGVSLQ--PRETYVITGQVL-HLEAHIYL 587
++K +FK +K + ++T P ++CGVSL ++ Y+I G+ + HI L
Sbjct: 72 EIKQIKMFKGPEKDIEF-----IYTAPSSAVCGVSLDVGGKKEYLIAGKAEGDGKMHITL 126
Query: 588 CGYIAKWREVTPRQRKGFRLLY 653
C +I W ++ Q+K Y
Sbjct: 127 CDFIVPWDTLSTTQKKSLNHRY 148
>J05593-1|AAA61186.1| 220|Homo sapiens TIMP protein.
Length = 220
Score = 59.3 bits (137), Expect = 1e-08
Identities = 42/142 (29%), Positives = 69/142 (48%), Gaps = 12/142 (8%)
Frame = +3
Query: 264 LTLALVAASCRVASACTCALEHPQTHYCKSDFVIVGRV---QKTFRGREDYD------IY 416
L L L+A R A AC+C+ HPQ +C +D VI + ++ G + Y Y
Sbjct: 12 LGLLLLATLLRPADACSCSPVHPQQAFCNADVVIRAKAVSEKEVDSGNDIYGNPIKRIQY 71
Query: 417 KVKIRNVFKATDKAVAALRSGRLFTPPHESLCGVSLQ--PRETYVITGQVL-HLEAHIYL 587
++K +FK +K + ++T P ++CGVSL ++ Y+I G+ + HI L
Sbjct: 72 EIKQIKMFKGPEKDIEF-----IYTAPSSAVCGVSLDVGGKKEYLIAGKAEGDGKMHITL 126
Query: 588 CGYIAKWREVTPRQRKGFRLLY 653
C +I W ++ Q+K Y
Sbjct: 127 CDFIVPWDTLSTTQKKSLNHRY 148
>BC071586-1|AAH71586.1| 220|Homo sapiens TIMP metallopeptidase
inhibitor 2 protein.
Length = 220
Score = 59.3 bits (137), Expect = 1e-08
Identities = 42/142 (29%), Positives = 69/142 (48%), Gaps = 12/142 (8%)
Frame = +3
Query: 264 LTLALVAASCRVASACTCALEHPQTHYCKSDFVIVGRV---QKTFRGREDYD------IY 416
L L L+A R A AC+C+ HPQ +C +D VI + ++ G + Y Y
Sbjct: 12 LGLLLLATLLRPADACSCSPVHPQQAFCNADVVIRAKAVSEKEVDSGNDIYGNPIKRIQY 71
Query: 417 KVKIRNVFKATDKAVAALRSGRLFTPPHESLCGVSLQ--PRETYVITGQVL-HLEAHIYL 587
++K +FK +K + ++T P ++CGVSL ++ Y+I G+ + HI L
Sbjct: 72 EIKQIKMFKGPEKDIEF-----IYTAPSSAVCGVSLDVGGKKEYLIAGKAEGDGKMHITL 126
Query: 588 CGYIAKWREVTPRQRKGFRLLY 653
C +I W ++ Q+K Y
Sbjct: 127 CDFIVPWDTLSTTQKKSLNHRY 148
>BC052605-1|AAH52605.1| 220|Homo sapiens TIMP metallopeptidase
inhibitor 2 protein.
Length = 220
Score = 59.3 bits (137), Expect = 1e-08
Identities = 42/142 (29%), Positives = 69/142 (48%), Gaps = 12/142 (8%)
Frame = +3
Query: 264 LTLALVAASCRVASACTCALEHPQTHYCKSDFVIVGRV---QKTFRGREDYD------IY 416
L L L+A R A AC+C+ HPQ +C +D VI + ++ G + Y Y
Sbjct: 12 LGLLLLATLLRPADACSCSPVHPQQAFCNADVVIRAKAVSEKEVDSGNDIYGNPIKRIQY 71
Query: 417 KVKIRNVFKATDKAVAALRSGRLFTPPHESLCGVSLQ--PRETYVITGQVL-HLEAHIYL 587
++K +FK +K + ++T P ++CGVSL ++ Y+I G+ + HI L
Sbjct: 72 EIKQIKMFKGPEKDIEF-----IYTAPSSAVCGVSLDVGGKKEYLIAGKAEGDGKMHITL 126
Query: 588 CGYIAKWREVTPRQRKGFRLLY 653
C +I W ++ Q+K Y
Sbjct: 127 CDFIVPWDTLSTTQKKSLNHRY 148
>U44385-1|AAC50729.1| 218|Homo sapiens tissue inhibitor of
metalloproteinases-2 protein.
Length = 218
Score = 58.0 bits (134), Expect = 3e-08
Identities = 41/142 (28%), Positives = 68/142 (47%), Gaps = 12/142 (8%)
Frame = +3
Query: 264 LTLALVAASCRVASACTCALEHPQTHYCKSDFVIVGRV---QKTFRGREDYD------IY 416
L L L+ R A AC+C+ HPQ +C +D VI + ++ G + Y Y
Sbjct: 10 LALGLLLPLLRPADACSCSPVHPQQAFCNADVVIRAKAVSEKEVDSGNDIYGNPIKRIQY 69
Query: 417 KVKIRNVFKATDKAVAALRSGRLFTPPHESLCGVSLQ--PRETYVITGQVL-HLEAHIYL 587
++K +FK +K + ++T P ++CGVSL ++ Y+I G+ + HI L
Sbjct: 70 EIKQIKMFKGPEKDIEF-----IYTAPSSAVCGVSLDVGGKKEYLIAGKAEGDGKMHITL 124
Query: 588 CGYIAKWREVTPRQRKGFRLLY 653
C +I W ++ Q+K Y
Sbjct: 125 CDFIVPWDTLSTTQKKSLNHRY 146
>Z84466-6|CAI42466.1| 136|Homo sapiens TIMP metallopeptidase
inhibitor 1 protein.
Length = 136
Score = 48.4 bits (110), Expect = 2e-05
Identities = 29/89 (32%), Positives = 43/89 (48%), Gaps = 5/89 (5%)
Frame = +3
Query: 306 ACTCALEHPQTHYCKSDFVIVGRVQKTFRGRED--YDIYKVKIRNVFKATDKAVAALRSG 479
ACTC HPQT +C SD VI + T + Y Y++K+ ++K A
Sbjct: 23 ACTCVPPHPQTAFCNSDLVIRAKFVGTPEVNQTTLYQRYEIKMTKMYKGFQALGDAADIR 82
Query: 480 RLFTPPHESLCGV---SLQPRETYVITGQ 557
++TP ES+CG S E ++I G+
Sbjct: 83 FVYTPAMESVCGYFHRSHNRSEEFLIAGE 111
>D11139-1|BAA01913.1| 166|Homo sapiens tissue inhibitor of
metalloproteinases protein.
Length = 166
Score = 46.8 bits (106), Expect = 7e-05
Identities = 25/86 (29%), Positives = 42/86 (48%), Gaps = 3/86 (3%)
Frame = +3
Query: 405 YDIYKVKIRNVFKATDKAVAALRSGRLFTPPHESLCGV---SLQPRETYVITGQVLHLEA 575
Y Y++K+ ++K A ++TP ES+CG S E ++I G++
Sbjct: 17 YQRYEIKMTKMYKGFQALGDAADIRFVYTPAMESVCGYFHRSHNRSEEFLIAGKLQDGLL 76
Query: 576 HIYLCGYIAKWREVTPRQRKGFRLLY 653
HI C ++A W ++ QR+GF Y
Sbjct: 77 HITTCSFVAPWNSLSLAQRRGFTKTY 102
>U38955-1|AAB17602.1| 170|Homo sapiens tissue inhibitor of
metalloproteinases-3 protein.
Length = 170
Score = 44.8 bits (101), Expect = 3e-04
Identities = 20/58 (34%), Positives = 34/58 (58%), Gaps = 1/58 (1%)
Frame = +3
Query: 483 LFTPPHESLCGVSLQPRE-TYVITGQVLHLEAHIYLCGYIAKWREVTPRQRKGFRLLY 653
+ T ESLCG+ L+ + Y++TG+V + + LC ++ +W ++T QRKG Y
Sbjct: 41 IHTEASESLCGLKLEVNKYQYLLTGRVYDGKMYTGLCNFVERWDQLTLSQRKGLNYRY 98
>X54533-1|CAA38400.1| 185|Homo sapiens Tissue inhibitor of
metalloproteinases, Type-2 protein.
Length = 185
Score = 43.2 bits (97), Expect = 8e-04
Identities = 33/121 (27%), Positives = 56/121 (46%), Gaps = 12/121 (9%)
Frame = +3
Query: 327 HPQTHYCKSDFVIVGRV---QKTFRGREDYDI------YKVKIRNVFKATDKAVAALRSG 479
HPQ +C +D VI + ++ G + Y Y++K +FK +K + +
Sbjct: 4 HPQQAFCNADVVIRAKAVSEKEVDSGNDIYGNPIKRIQYEIKQIKMFKGPEKDIEFI--- 60
Query: 480 RLFTPPHESLCGVSLQP--RETYVITGQVL-HLEAHIYLCGYIAKWREVTPRQRKGFRLL 650
+T P +CGVSL ++ Y+I G+ + HI LC +I W ++ Q+K
Sbjct: 61 --YTAPSSVVCGVSLDVGGKKEYLIAGKAEGDGKMHITLCDFIVPWDTLSTTQKKSLNHR 118
Query: 651 Y 653
Y
Sbjct: 119 Y 119
>Z84466-4|CAI42464.1| 143|Homo sapiens TIMP metallopeptidase
inhibitor 1 protein.
Length = 143
Score = 41.1 bits (92), Expect = 0.003
Identities = 20/60 (33%), Positives = 32/60 (53%), Gaps = 3/60 (5%)
Frame = +3
Query: 483 LFTPPHESLCGV---SLQPRETYVITGQVLHLEAHIYLCGYIAKWREVTPRQRKGFRLLY 653
++TP ES+CG S E ++I G++ HI C ++A W ++ QR+GF Y
Sbjct: 20 VYTPAMESVCGYFHRSHNRSEEFLIAGKLQDGLLHITTCSFVAPWNSLSLAQRRGFTKTY 79
>Z84466-7|CAI42467.1| 96|Homo sapiens TIMP metallopeptidase
inhibitor 1 protein.
Length = 96
Score = 38.3 bits (85), Expect = 0.024
Identities = 18/48 (37%), Positives = 26/48 (54%), Gaps = 2/48 (4%)
Frame = +3
Query: 306 ACTCALEHPQTHYCKSDFVIVGRVQKTFRGRED--YDIYKVKIRNVFK 443
ACTC HPQT +C SD VI + T + Y Y++K+ ++K
Sbjct: 35 ACTCVPPHPQTAFCNSDLVIRAKFVGTPEVNQTTLYQRYEIKMTKMYK 82
>S68860-1|AAD14025.1| 50|Homo sapiens timp-2 protein.
Length = 50
Score = 33.5 bits (73), Expect = 0.67
Identities = 14/31 (45%), Positives = 19/31 (61%)
Frame = +3
Query: 264 LTLALVAASCRVASACTCALEHPQTHYCKSD 356
L L L+A R A AC+C+ HPQ +C +D
Sbjct: 12 LGLLLLATLLRPADACSCSPVHPQQAFCNAD 42
>L47361-1|AAA75558.1| 40|Homo sapiens tissue inhibitor of
metalloproteinase 1 protein.
Length = 40
Score = 31.5 bits (68), Expect = 2.7
Identities = 11/17 (64%), Positives = 12/17 (70%)
Frame = +3
Query: 306 ACTCALEHPQTHYCKSD 356
ACTC HPQT +C SD
Sbjct: 23 ACTCVPPHPQTAFCNSD 39
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 94,828,944
Number of Sequences: 237096
Number of extensions: 1907203
Number of successful extensions: 4904
Number of sequences better than 10.0: 43
Number of HSP's better than 10.0 without gapping: 4751
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4845
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 7310122300
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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