Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= bmmt5f01
(600 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_O97479 Cluster: CG1982-PA; n=17; Bilateria|Rep: CG1982-... 299 3e-80
UniRef50_Q00796 Cluster: Sorbitol dehydrogenase; n=35; Eumetazoa... 267 2e-70
UniRef50_Q58D31 Cluster: Sorbitol dehydrogenase; n=8; Eukaryota|... 260 1e-68
UniRef50_Q6PGX2 Cluster: Zgc:63674; n=2; Danio rerio|Rep: Zgc:63... 258 7e-68
UniRef50_Q7QAQ4 Cluster: ENSANGP00000011378; n=3; Culicidae|Rep:... 241 7e-63
UniRef50_Q02912 Cluster: Sorbitol dehydrogenase; n=1; Bombyx mor... 239 3e-62
UniRef50_Q0TT56 Cluster: L-iditol 2-dehydrogenase; n=3; Clostrid... 226 4e-58
UniRef50_Q67XB8 Cluster: Sorbitol dehydrogenase-like protein; n=... 224 1e-57
UniRef50_A1CFY8 Cluster: Xylitol dehydrogenase; n=22; Ascomycota... 222 6e-57
UniRef50_UPI0000E46CC1 Cluster: PREDICTED: similar to SORD prote... 221 1e-56
UniRef50_Q16R00 Cluster: Alcohol dehydrogenase; n=3; Culicidae|R... 215 9e-55
UniRef50_A3TNY9 Cluster: Zinc-binding dehydrogenase; n=5; Actino... 208 6e-53
UniRef50_Q5V6U8 Cluster: Zinc-binding dehydrogenase; n=1; Haloar... 208 8e-53
UniRef50_Q06004 Cluster: Sorbitol dehydrogenase; n=5; Bacillales... 207 1e-52
UniRef50_Q1J2J1 Cluster: Alcohol dehydrogenase GroES-like; n=1; ... 202 4e-51
UniRef50_Q5KPZ2 Cluster: Sorbitol dehydrogenase, putative; n=1; ... 202 7e-51
UniRef50_Q07786 Cluster: Sorbitol dehydrogenase 2; n=8; Saccharo... 200 2e-50
UniRef50_Q4WT02 Cluster: Xylitol dehydrogenase; n=8; Pezizomycot... 200 2e-50
UniRef50_P36624 Cluster: Putative sorbitol dehydrogenase; n=1; S... 198 8e-50
UniRef50_A5AB83 Cluster: Contig An08c0230, complete genome; n=9;... 193 3e-48
UniRef50_Q4WT03 Cluster: L-arabinitol 4-dehydrogenase; n=5; Tric... 190 3e-47
UniRef50_P22144 Cluster: D-xylulose reductase; n=8; Saccharomyce... 189 5e-47
UniRef50_A1DBH5 Cluster: Alcohol dehydrogenase; n=3; Pezizomycot... 187 2e-46
UniRef50_Q5K981 Cluster: L-iditol 2-dehydrogenase, putative; n=6... 184 1e-45
UniRef50_A3Q0B6 Cluster: Alcohol dehydrogenase GroES domain prot... 182 4e-45
UniRef50_Q0U204 Cluster: Putative uncharacterized protein; n=1; ... 175 7e-43
UniRef50_Q1QUA2 Cluster: Alcohol dehydrogenase, zinc-binding; n=... 174 1e-42
UniRef50_Q59545 Cluster: D-xylulose reductase; n=36; Bacteria|Re... 172 5e-42
UniRef50_Q5WJ77 Cluster: Sorbitol dehydrogenase; n=1; Bacillus c... 172 6e-42
UniRef50_Q98D10 Cluster: Putative D-xylulose reductase; n=9; cel... 171 8e-42
UniRef50_P77280 Cluster: Uncharacterized zinc-type alcohol dehyd... 171 1e-41
UniRef50_Q4PCL3 Cluster: Putative uncharacterized protein; n=1; ... 170 2e-41
UniRef50_Q4PHJ5 Cluster: Putative uncharacterized protein; n=1; ... 170 2e-41
UniRef50_Q89F70 Cluster: L-idonate 5-dehydrogenase; n=1; Bradyrh... 169 6e-41
UniRef50_Q2UHR2 Cluster: Sorbitol dehydrogenase; n=8; Ascomycota... 167 1e-40
UniRef50_A7F503 Cluster: Putative uncharacterized protein; n=1; ... 165 9e-40
UniRef50_A1CNK3 Cluster: Xylitol dehydrogenase XdhB, putative; n... 162 7e-39
UniRef50_A7II35 Cluster: Alcohol dehydrogenase GroES domain prot... 161 1e-38
UniRef50_A3DI68 Cluster: Alcohol dehydrogenase GroES-like protei... 160 2e-38
UniRef50_Q5KPJ4 Cluster: Sorbitol dehydrogenase, putative; n=1; ... 159 3e-38
UniRef50_Q7S9B3 Cluster: Putative uncharacterized protein NCU070... 159 6e-38
UniRef50_A2QU04 Cluster: Catalytic activity: L-iditol + NAD(+) =... 159 6e-38
UniRef50_Q0UEG3 Cluster: Putative uncharacterized protein; n=1; ... 155 6e-37
UniRef50_A3GIE9 Cluster: Sorbitol dehydrogenase; n=2; Saccharomy... 154 1e-36
UniRef50_Q3ACJ3 Cluster: Sorbitol dehydrogenase; n=1; Carboxydot... 153 3e-36
UniRef50_A1DK00 Cluster: Alcohol dehydrogenase; n=7; Pezizomycot... 152 7e-36
UniRef50_Q5KAN3 Cluster: Xylitol dehydrogenase, putative; n=1; F... 151 9e-36
UniRef50_UPI0000DD8301 Cluster: PREDICTED: similar to Sorbitol d... 149 5e-35
UniRef50_Q5LQR4 Cluster: L-idonate 5-dehydrogenase; n=13; Alphap... 144 1e-33
UniRef50_Q5KJG0 Cluster: Xylitol dehydrogenase, putative; n=1; F... 144 1e-33
UniRef50_Q01VI1 Cluster: Alcohol dehydrogenase GroES domain prot... 144 2e-33
UniRef50_Q39JN7 Cluster: Zinc-containing alcohol dehydrogenase s... 143 2e-33
UniRef50_A1WNS6 Cluster: Alcohol dehydrogenase GroES domain prot... 138 7e-32
UniRef50_A0GHL5 Cluster: Alcohol dehydrogenase GroES-like; n=1; ... 135 9e-31
UniRef50_A5D1M5 Cluster: Threonine dehydrogenase and related Zn-... 133 3e-30
UniRef50_A6X6E2 Cluster: Alcohol dehydrogenase GroES domain prot... 132 5e-30
UniRef50_A0QWX1 Cluster: Oxidoreductase, zinc-binding dehydrogen... 132 6e-30
UniRef50_A6BDE4 Cluster: Putative uncharacterized protein; n=2; ... 130 3e-29
UniRef50_Q930C9 Cluster: IdnD L-idonate 5-dehydrogenase; n=4; Al... 129 4e-29
UniRef50_Q81V29 Cluster: Alcohol dehydrogenase, zinc-containing;... 129 4e-29
UniRef50_A0NKD6 Cluster: Zc-binding dehydrogenase; n=3; Oenococc... 129 4e-29
UniRef50_Q5KJK1 Cluster: Zinc-binding dehydrogenase, putative; n... 129 4e-29
UniRef50_A5FZ32 Cluster: Alcohol dehydrogenase GroES domain prot... 129 6e-29
UniRef50_A3PQM0 Cluster: Alcohol dehydrogenase GroES domain prot... 127 2e-28
UniRef50_Q8EL78 Cluster: Alcohol dehydrogenase; n=1; Oceanobacil... 126 4e-28
UniRef50_A3DCE7 Cluster: Alcohol dehydrogenase GroES-like protei... 126 5e-28
UniRef50_A1SCW8 Cluster: Alcohol dehydrogenase, zinc-binding dom... 126 5e-28
UniRef50_Q38ZV8 Cluster: Zinc-containing alcohol dehydrogenase s... 125 7e-28
UniRef50_Q8ELG9 Cluster: Sorbitol dehydrogenase; n=2; Bacillacea... 125 9e-28
UniRef50_Q188T6 Cluster: Putative sugar-phosphate dehydrogenase;... 124 1e-27
UniRef50_A4FHA7 Cluster: Zinc-binding dehydrogenase; n=1; Saccha... 124 2e-27
UniRef50_A6LBP5 Cluster: Putative uncharacterized protein; n=1; ... 123 3e-27
UniRef50_Q7SHA1 Cluster: Putative uncharacterized protein NCU019... 92 6e-27
UniRef50_A5I7E3 Cluster: Sorbitol dehydrogenase; n=7; Clostridiu... 122 6e-27
UniRef50_A0V2V9 Cluster: Alcohol dehydrogenase GroES-like; n=1; ... 122 6e-27
UniRef50_Q9VDQ9 Cluster: CG4836-PC, isoform C; n=4; Eukaryota|Re... 122 6e-27
UniRef50_Q9S270 Cluster: Putative zinc-binding alcohol dehydroge... 122 9e-27
UniRef50_Q2AGV2 Cluster: Zinc-containing alcohol dehydrogenase s... 121 1e-26
UniRef50_Q01PH7 Cluster: Alcohol dehydrogenase GroES domain prot... 120 2e-26
UniRef50_A3I7D7 Cluster: Zinc-containing alcohol dehydrogenase, ... 119 5e-26
UniRef50_Q9K5Y6 Cluster: L-iditol 2-dehydrogenase; n=8; Bacteria... 118 8e-26
UniRef50_A1UQB9 Cluster: Alcohol dehydrogenase GroES domain prot... 118 8e-26
UniRef50_Q3IVK2 Cluster: Zinc-containing alcohol dehydrogenase; ... 118 1e-25
UniRef50_Q927H5 Cluster: Lin2813 protein; n=16; Firmicutes|Rep: ... 116 3e-25
UniRef50_Q7CVQ9 Cluster: AGR_L_281p; n=7; Alphaproteobacteria|Re... 116 4e-25
UniRef50_Q88S92 Cluster: L-iditol 2-dehydrogenase; n=7; Firmicut... 116 6e-25
UniRef50_Q65L05 Cluster: YjmD; n=1; Bacillus licheniformis ATCC ... 116 6e-25
UniRef50_Q5V6V7 Cluster: Zinc-binding dehydrogenase; n=1; Haloar... 116 6e-25
UniRef50_Q3A2I8 Cluster: Putative zinc-containing alcohol dehydr... 115 7e-25
UniRef50_Q1IQV5 Cluster: Alcohol dehydrogenase, zinc-binding; n=... 115 7e-25
UniRef50_A1D0R7 Cluster: Alcohol dehydrogenase; n=2; Trichocomac... 115 7e-25
UniRef50_A6W9X6 Cluster: Alcohol dehydrogenase GroES domain prot... 114 1e-24
UniRef50_A1HSQ8 Cluster: Alcohol dehydrogenase GroES domain prot... 114 2e-24
UniRef50_Q4LED8 Cluster: Dehydrogenase; n=1; uncultured crenarch... 113 2e-24
UniRef50_Q9HWM8 Cluster: 2,3-butanediol dehydrogenase; n=24; Pro... 113 3e-24
UniRef50_Q8DIZ5 Cluster: Sorbitol dehydrogenase; n=6; Cyanobacte... 113 3e-24
UniRef50_Q2RG84 Cluster: Alcohol dehydrogenase superfamily, zinc... 113 4e-24
UniRef50_A0TC93 Cluster: Alcohol dehydrogenase GroES-like; n=15;... 113 4e-24
UniRef50_A4J9K3 Cluster: Alcohol dehydrogenase GroES domain prot... 112 5e-24
UniRef50_A1R5Y9 Cluster: L-threonine 3-dehydrogenase; n=1; Arthr... 112 5e-24
UniRef50_P39346 Cluster: L-idonate 5-dehydrogenase; n=17; Gammap... 112 5e-24
UniRef50_Q9KGB7 Cluster: Sorbitol dehydrogenase; n=28; Bacillale... 112 7e-24
UniRef50_Q5WC08 Cluster: Galactitol-1-phosphate 5-dehydrogenase;... 112 7e-24
UniRef50_A1SFU6 Cluster: Alcohol dehydrogenase, zinc-binding dom... 112 7e-24
UniRef50_A0UVE8 Cluster: Alcohol dehydrogenase GroES-like; n=1; ... 112 7e-24
UniRef50_Q1Q2R9 Cluster: Similar to sorbitol dehydrogenase; n=1;... 111 9e-24
UniRef50_Q025V7 Cluster: Alcohol dehydrogenase GroES domain prot... 111 1e-23
UniRef50_A1UPQ2 Cluster: Alcohol dehydrogenase GroES domain prot... 111 1e-23
UniRef50_A1DNE9 Cluster: Alcohol dehydrogenase; n=4; Trichocomac... 111 1e-23
UniRef50_Q57517 Cluster: Uncharacterized zinc-type alcohol dehyd... 111 1e-23
UniRef50_UPI0000553E21 Cluster: Zinc-containing alcohol dehydrog... 111 2e-23
UniRef50_A4XHJ7 Cluster: Alcohol dehydrogenase GroES domain prot... 111 2e-23
UniRef50_Q8ZJN2 Cluster: L-threonine 3-dehydrogenase; n=41; Bact... 111 2e-23
UniRef50_UPI000050F926 Cluster: COG1063: Threonine dehydrogenase... 110 2e-23
UniRef50_Q65L02 Cluster: Putative uncharacterized protein; n=1; ... 110 2e-23
UniRef50_A6VRA2 Cluster: Alcohol dehydrogenase GroES domain prot... 110 2e-23
UniRef50_UPI00015B5FCF Cluster: PREDICTED: similar to putative z... 109 4e-23
UniRef50_Q8KQG6 Cluster: Mannitol dehydrogenase; n=12; Bacteria|... 109 4e-23
UniRef50_A6W685 Cluster: Alcohol dehydrogenase zinc-binding doma... 109 5e-23
UniRef50_P39713 Cluster: Zinc-type alcohol dehydrogenase-like pr... 109 5e-23
UniRef50_A5D4M1 Cluster: Zn-dependent alcohol dehydrogenases; n=... 109 6e-23
UniRef50_UPI000038E1A4 Cluster: hypothetical protein Faci_030008... 108 9e-23
UniRef50_Q829Q5 Cluster: Putative zinc-binding dehydrogenase; n=... 108 9e-23
UniRef50_Q97TZ4 Cluster: Sorbitol dehydrogenase; n=4; Sulfolobac... 108 9e-23
UniRef50_P39400 Cluster: Uncharacterized zinc-type alcohol dehyd... 108 1e-22
UniRef50_P38105 Cluster: Starvation-sensing protein rspB; n=36; ... 108 1e-22
UniRef50_A5JSX4 Cluster: Zinc-containing alcohol dehydrogenase; ... 107 1e-22
UniRef50_A0JXR0 Cluster: Alcohol dehydrogenase, zinc-binding dom... 107 2e-22
UniRef50_Q9RKG0 Cluster: Putative dehydrogenase; n=1; Streptomyc... 107 3e-22
UniRef50_Q5BBC2 Cluster: Putative uncharacterized protein; n=1; ... 107 3e-22
UniRef50_A2R6Z1 Cluster: Catalytic activity: L-iditol + NAD(+) <... 107 3e-22
UniRef50_UPI00015970BD Cluster: GutB1; n=1; Bacillus amyloliquef... 106 3e-22
UniRef50_Q1ARQ8 Cluster: Alcohol dehydrogenase GroES-like protei... 106 3e-22
UniRef50_O58389 Cluster: Probable L-threonine 3-dehydrogenase; n... 106 3e-22
UniRef50_Q9RTU4 Cluster: L-threonine 3-dehydrogenase; n=178; Bac... 106 3e-22
UniRef50_Q987C5 Cluster: Alcohol dehydrogenase; n=4; Rhizobiales... 106 5e-22
UniRef50_Q44P31 Cluster: Zinc-containing alcohol dehydrogenase s... 106 5e-22
UniRef50_Q3W5D6 Cluster: Zinc-containing alcohol dehydrogenase s... 106 5e-22
UniRef50_A3Q0B4 Cluster: Alcohol dehydrogenase GroES domain prot... 106 5e-22
UniRef50_A0LL41 Cluster: Alcohol dehydrogenase GroES domain prot... 106 5e-22
UniRef50_Q6BC32 Cluster: Glycerol dehydrogenase; n=3; Saccharomy... 106 5e-22
UniRef50_Q46NN2 Cluster: Zinc-containing alcohol dehydrogenase s... 105 6e-22
UniRef50_Q5B6Y0 Cluster: Putative uncharacterized protein; n=1; ... 105 6e-22
UniRef50_Q62AB8 Cluster: Oxidoreductase, zinc-binding dehydrogen... 105 8e-22
UniRef50_Q59715 Cluster: Benzyl alcohol dehydrogenase II; n=5; P... 105 8e-22
UniRef50_Q72U55 Cluster: Zinc binding dehydrogenase; n=4; Leptos... 105 1e-21
UniRef50_Q12E06 Cluster: Alcohol dehydrogenase GroES-like; n=2; ... 105 1e-21
UniRef50_A3U1C0 Cluster: Threonine 3-dehydrogenase; n=1; Oceanic... 105 1e-21
UniRef50_Q3ZWK2 Cluster: Alcohol dehydrogenase, zinc-containing;... 104 1e-21
UniRef50_A5WI29 Cluster: Alcohol dehydrogenase, zinc-binding dom... 104 2e-21
UniRef50_Q9UAT1 Cluster: Putative uncharacterized protein; n=1; ... 104 2e-21
UniRef50_Q0UBF8 Cluster: Putative uncharacterized protein; n=1; ... 103 2e-21
UniRef50_Q0RW76 Cluster: Probable Zn-containing alcohol dehydrog... 103 3e-21
UniRef50_Q5K658 Cluster: Sorbitol dehydrogenase; n=2; Dikarya|Re... 103 3e-21
UniRef50_Q8R7K0 Cluster: L-threonine 3-dehydrogenase; n=3; cellu... 103 3e-21
UniRef50_Q3B3S5 Cluster: Alcohol dehydrogenase, zinc-containing;... 103 4e-21
UniRef50_Q1AZ51 Cluster: Alcohol dehydrogenase GroES-like protei... 103 4e-21
UniRef50_A3JMN6 Cluster: Dehydrogenase; n=4; Bacteria|Rep: Dehyd... 103 4e-21
UniRef50_Q565X2 Cluster: 6-hydroxycylohex-1-ene-1-carboxyl-CoA d... 102 6e-21
UniRef50_A5V1N3 Cluster: Alcohol dehydrogenase GroES domain prot... 102 6e-21
UniRef50_A0QTC9 Cluster: 2-deoxy-scyllo-inosamine dehydrogenase;... 101 1e-20
UniRef50_A2R610 Cluster: Catalytic activity:; n=5; Trichocomacea... 101 1e-20
UniRef50_Q8Y414 Cluster: Lmo2663 protein; n=14; Firmicutes|Rep: ... 101 2e-20
UniRef50_Q1AVM7 Cluster: Alcohol dehydrogenase GroES-like protei... 101 2e-20
UniRef50_A3S6P0 Cluster: L-threonine 3-dehydrogenase; n=2; Bacte... 101 2e-20
UniRef50_Q4PP82 Cluster: Putative zinc-containing alcohol dehydr... 101 2e-20
UniRef50_A0JVX4 Cluster: Alcohol dehydrogenase GroES domain prot... 100 3e-20
UniRef50_A1UG38 Cluster: Alcohol dehydrogenase GroES domain prot... 99 4e-20
UniRef50_Q1HPY0 Cluster: Zinc-containing alcohol dehydrogenase; ... 99 4e-20
UniRef50_Q9Z9U1 Cluster: Sorbitol dehydrogenase; n=14; Bacillale... 99 4e-20
UniRef50_Q5LVU9 Cluster: Sorbitol dehydrogenase, putative; n=13;... 100 5e-20
UniRef50_Q1IQV6 Cluster: Alcohol dehydrogenase GroES-like; n=2; ... 100 5e-20
UniRef50_P0A9S4 Cluster: Galactitol-1-phosphate 5-dehydrogenase;... 100 5e-20
UniRef50_Q2G759 Cluster: GroES-related; n=1; Novosphingobium aro... 99 7e-20
UniRef50_A1RYE2 Cluster: Alcohol dehydrogenase GroES domain prot... 99 7e-20
UniRef50_A4QH16 Cluster: Putative uncharacterized protein; n=1; ... 99 9e-20
UniRef50_Q92YT8 Cluster: Putative; n=2; Alphaproteobacteria|Rep:... 98 1e-19
UniRef50_Q8DK96 Cluster: Tll0970 protein; n=6; Cyanobacteria|Rep... 98 1e-19
UniRef50_Q1IJN0 Cluster: Alcohol dehydrogenase GroES-like; n=1; ... 98 1e-19
UniRef50_A6VLA0 Cluster: Alcohol dehydrogenase GroES domain prot... 98 1e-19
UniRef50_A5D5N1 Cluster: Threonine dehydrogenase and related Zn-... 98 1e-19
UniRef50_UPI000051A87A Cluster: PREDICTED: similar to R04B5.5; n... 98 2e-19
UniRef50_Q62K93 Cluster: Oxidoreductase, zinc-binding dehydrogen... 98 2e-19
UniRef50_A0V7I1 Cluster: Alcohol dehydrogenase GroES-like; n=2; ... 98 2e-19
UniRef50_Q8ELI9 Cluster: Sorbitol dehydrogenase; n=2; Bacillacea... 97 2e-19
UniRef50_A4AMR5 Cluster: Zn-dependent alcohol dehydrogenase; n=2... 97 2e-19
UniRef50_O35045 Cluster: Zinc-containing alcohol dehydrogenase; ... 97 3e-19
UniRef50_Q39TG2 Cluster: Alcohol dehydrogenase superfamily, zinc... 96 5e-19
UniRef50_A5ZM46 Cluster: Putative uncharacterized protein; n=2; ... 96 5e-19
UniRef50_Q0UDN4 Cluster: Putative uncharacterized protein; n=2; ... 96 5e-19
UniRef50_Q1PUQ4 Cluster: Similar to zinc-containing dehydrogenas... 96 6e-19
UniRef50_A4XGJ9 Cluster: Alcohol dehydrogenase, zinc-binding dom... 95 9e-19
UniRef50_Q1QWS0 Cluster: Alcohol dehydrogenase GroES-like protei... 95 1e-18
UniRef50_A6LR91 Cluster: Alcohol dehydrogenase GroES domain prot... 95 1e-18
UniRef50_A4FJI0 Cluster: Putative zinc-binding alcohol dehydroge... 95 1e-18
UniRef50_A0JVW4 Cluster: Alcohol dehydrogenase GroES domain prot... 95 1e-18
UniRef50_Q8Z6Z4 Cluster: Starvation sensing protein RspB; n=1; S... 95 1e-18
UniRef50_A0IRE9 Cluster: Alcohol dehydrogenase GroES-like; n=1; ... 94 3e-18
UniRef50_UPI00015BC9A2 Cluster: UPI00015BC9A2 related cluster; n... 93 3e-18
UniRef50_A4XEZ1 Cluster: Alcohol dehydrogenase, zinc-binding dom... 93 3e-18
UniRef50_A4FFG8 Cluster: Probable alcohol dehydrogenase; n=1; Sa... 93 3e-18
UniRef50_A2UF68 Cluster: Alcohol dehydrogenase GroES domain prot... 93 3e-18
UniRef50_A0QZF0 Cluster: Oxidoreductase, zinc-binding dehydrogen... 93 3e-18
UniRef50_Q8EMM7 Cluster: Dehydrogenase; n=1; Oceanobacillus ihey... 93 5e-18
UniRef50_Q5HLF5 Cluster: Sorbitol dehydrogenase, putative; n=10;... 93 5e-18
UniRef50_A5FCD7 Cluster: Alcohol dehydrogenase, zinc-binding dom... 93 5e-18
UniRef50_A6M074 Cluster: Alcohol dehydrogenase GroES domain prot... 92 8e-18
UniRef50_A7RKY5 Cluster: Predicted protein; n=1; Nematostella ve... 92 8e-18
UniRef50_Q63FG9 Cluster: Zinc-containing alcohol dehydrogenase; ... 92 1e-17
UniRef50_Q46N56 Cluster: Zinc-containing alcohol dehydrogenase s... 92 1e-17
UniRef50_A1SLI2 Cluster: Alcohol dehydrogenase GroES domain prot... 92 1e-17
UniRef50_A3H8A1 Cluster: Alcohol dehydrogenase GroES-like; n=1; ... 92 1e-17
UniRef50_Q6NDJ8 Cluster: Putative Zn-binding dehydrogenase; n=1;... 91 1e-17
UniRef50_Q0LSY1 Cluster: Alcohol dehydrogenase, zinc-binding:Alc... 91 1e-17
UniRef50_Q7N973 Cluster: Similarities with different types of de... 91 2e-17
UniRef50_Q2LQ73 Cluster: Zinc-binding dehydrogenase; n=2; Bacter... 91 2e-17
UniRef50_Q5BFT1 Cluster: Putative uncharacterized protein; n=1; ... 91 2e-17
UniRef50_Q0TXS2 Cluster: Putative uncharacterized protein; n=2; ... 91 2e-17
UniRef50_Q7D7T9 Cluster: Zinc-binding dehydrogenase; n=15; Mycob... 91 2e-17
UniRef50_Q0FV22 Cluster: Sorbitol dehydrogenase; n=1; Roseovariu... 91 2e-17
UniRef50_A4XUM5 Cluster: Alcohol dehydrogenase GroES domain prot... 91 2e-17
UniRef50_A0JVZ1 Cluster: Alcohol dehydrogenase GroES domain prot... 91 2e-17
UniRef50_Q67N85 Cluster: L-threonine 3-dehydrogenase; n=10; Bact... 91 2e-17
UniRef50_A5V2Z1 Cluster: Alcohol dehydrogenase, zinc-binding dom... 90 3e-17
UniRef50_Q7U377 Cluster: Putative Zinc-binding dehydrogenase; n=... 90 4e-17
UniRef50_Q24T43 Cluster: Putative uncharacterized protein; n=1; ... 90 4e-17
UniRef50_A0QS68 Cluster: 2-deoxy-scyllo-inosamine dehydrogenase;... 90 4e-17
UniRef50_Q0RVL1 Cluster: Zn-dependent alcohol dehydrogenase; n=1... 89 1e-16
UniRef50_A3H9A2 Cluster: Alcohol dehydrogenase GroES-like; n=1; ... 89 1e-16
UniRef50_Q0CVZ1 Cluster: Putative uncharacterized protein; n=1; ... 88 1e-16
UniRef50_A0LGB6 Cluster: Alcohol dehydrogenase GroES domain prot... 88 2e-16
UniRef50_Q5A958 Cluster: Potential secondary alcohol dehydrogena... 88 2e-16
UniRef50_A2QFZ8 Cluster: Catalytic activity: alcohol dehydrogena... 88 2e-16
UniRef50_Q9P6I8 Cluster: Glutathione-dependent formaldehyde dehy... 87 3e-16
UniRef50_A3DME0 Cluster: Alcohol dehydrogenase GroES domain prot... 87 3e-16
UniRef50_Q48FD6 Cluster: Oxidoreductase, zinc-binding; n=2; Pseu... 87 4e-16
UniRef50_Q1PZD2 Cluster: Strong similarity to L-threonine dehydr... 87 4e-16
UniRef50_Q2U8M8 Cluster: Threonine dehydrogenase and related Zn-... 87 4e-16
UniRef50_Q6MJG4 Cluster: Putative alcohol dehydrogenase I; n=1; ... 86 7e-16
UniRef50_Q60AS0 Cluster: Alcohol dehydrogenase, zinc-containing;... 85 9e-16
UniRef50_Q9ZEX7 Cluster: Dehydrogenase; n=1; Thiobacillus sp.|Re... 85 9e-16
UniRef50_Q2MFS3 Cluster: Putative 3-amino-2,3-dideoxy-scyllo-ino... 85 9e-16
UniRef50_A0JVX5 Cluster: Alcohol dehydrogenase, zinc-binding dom... 85 9e-16
UniRef50_A0HHZ1 Cluster: Alcohol dehydrogenase GroES-like; n=1; ... 85 9e-16
UniRef50_Q7UT38 Cluster: Zinc-type alcohol dehydrogenase; n=1; P... 85 1e-15
UniRef50_Q7US13 Cluster: Probable zinc-type alcohol dehydrogenas... 85 2e-15
UniRef50_O45687 Cluster: Alcohol dehydrogenase 2; n=3; Caenorhab... 84 3e-15
UniRef50_UPI00005F10EF Cluster: COG1063: Threonine dehydrogenase... 83 4e-15
UniRef50_Q2KCX6 Cluster: Probable zinc-type alcohol dehydrogenas... 83 4e-15
UniRef50_Q0SAT0 Cluster: Zn-containing alcohol dehdyrogenase; n=... 83 4e-15
UniRef50_A0LRZ3 Cluster: Alcohol dehydrogenase GroES domain prot... 83 4e-15
UniRef50_Q4LED7 Cluster: Sorbitol dehydrogenase; n=1; uncultured... 83 4e-15
UniRef50_Q89IR8 Cluster: Bll5566 protein; n=2; Rhizobiales|Rep: ... 83 5e-15
UniRef50_A1SLY9 Cluster: Alcohol dehydrogenase GroES domain prot... 83 5e-15
UniRef50_Q9HJX2 Cluster: Alcohol dehydrogenase related protein; ... 83 5e-15
UniRef50_Q9RS48 Cluster: Alcohol dehydrogenase, zinc-containing;... 83 6e-15
UniRef50_A6LDY7 Cluster: Putative zinc-type alcohol dehydrogenas... 83 6e-15
UniRef50_A0RV95 Cluster: L-iditol 2-dehydrogenase/threonine dehy... 82 8e-15
UniRef50_Q8A1P2 Cluster: Sorbitol dehydrogenase; n=4; Bacteroide... 82 1e-14
UniRef50_A1WT70 Cluster: Alcohol dehydrogenase, zinc-binding dom... 82 1e-14
UniRef50_Q8UB54 Cluster: Zinc-binding dehydrogenase; n=3; Rhizob... 81 2e-14
UniRef50_Q6AAC4 Cluster: Alcohol dehydrogenase; n=1; Propionibac... 81 2e-14
UniRef50_Q62CY1 Cluster: Alcohol dehydrogenase, zinc-containing;... 81 2e-14
UniRef50_A7H7S9 Cluster: Alcohol dehydrogenase GroES domain prot... 81 2e-14
UniRef50_Q5V676 Cluster: Alcohol dehydrogenase; n=7; cellular or... 81 2e-14
UniRef50_Q73RL3 Cluster: Sorbitol dehydrogenase, putative; n=1; ... 81 3e-14
UniRef50_Q5YU97 Cluster: Putative dehydrogenase; n=1; Nocardia f... 81 3e-14
UniRef50_UPI0000498928 Cluster: zinc-containing alcohol dehydrog... 80 3e-14
UniRef50_Q00SV0 Cluster: COG1064: Zn-dependent alcohol dehydroge... 80 3e-14
UniRef50_Q98GG6 Cluster: L-iditol 2-dehydrogenase; n=5; Alphapro... 80 5e-14
UniRef50_Q6AA39 Cluster: Zinc-binding dehydrogenase; n=1; Propio... 80 5e-14
UniRef50_Q59VG4 Cluster: Potential butanediol dehydrogenase; n=7... 80 5e-14
UniRef50_Q97VW0 Cluster: Alcohol dehydrogenase; n=7; Thermoprote... 80 5e-14
UniRef50_Q98CF7 Cluster: 2,3-butanediol dehydrogenase; n=5; Rhiz... 79 6e-14
UniRef50_A0UVK1 Cluster: Alcohol dehydrogenase, zinc-binding; n=... 79 6e-14
UniRef50_Q9WYP3 Cluster: Alcohol dehydrogenase, zinc-containing;... 79 8e-14
UniRef50_Q767G1 Cluster: Putative dehydrogenase; n=1; Actinoplan... 79 8e-14
UniRef50_Q2J7M3 Cluster: Alcohol dehydrogenase GroES-like; n=3; ... 79 1e-13
UniRef50_A7M5E0 Cluster: Putative uncharacterized protein; n=1; ... 79 1e-13
UniRef50_A7HAS7 Cluster: Alcohol dehydrogenase GroES domain prot... 79 1e-13
UniRef50_A6EYW6 Cluster: Zinc-containing alcohol dehydrogenase s... 79 1e-13
UniRef50_P77360 Cluster: Uncharacterized zinc-type alcohol dehyd... 79 1e-13
UniRef50_Q7NR39 Cluster: Probable glutathione-dependent aldehyde... 78 1e-13
UniRef50_Q11C06 Cluster: Alcohol dehydrogenase GroES-like; n=1; ... 78 1e-13
UniRef50_A4XIU4 Cluster: Alcohol dehydrogenase GroES domain prot... 78 1e-13
UniRef50_Q97VB8 Cluster: Alcohol dehydrogenase; n=1; Sulfolobus ... 78 1e-13
UniRef50_Q8ZU64 Cluster: Alcohol dehydrogenase; n=5; Thermoprote... 78 1e-13
UniRef50_A1W5R7 Cluster: Alcohol dehydrogenase GroES domain prot... 78 2e-13
UniRef50_A7SKJ4 Cluster: Predicted protein; n=1; Nematostella ve... 78 2e-13
UniRef50_A0V2V8 Cluster: Alcohol dehydrogenase GroES-like; n=1; ... 77 2e-13
UniRef50_Q74FN3 Cluster: Alcohol dehydrogenase, zinc-containing;... 77 3e-13
UniRef50_A5N5N6 Cluster: Zn-dependent dehydrogenase; n=1; Clostr... 77 3e-13
UniRef50_A4GII5 Cluster: Sorbitol dehydrogenase; n=3; environmen... 77 3e-13
UniRef50_A2SNX9 Cluster: Zinc-binding dehydrogenase; n=1; Methyl... 77 3e-13
UniRef50_A1BBU7 Cluster: Alcohol dehydrogenase, zinc-binding dom... 77 3e-13
UniRef50_A6NT70 Cluster: Putative uncharacterized protein; n=1; ... 77 4e-13
UniRef50_A5VBI0 Cluster: Alcohol dehydrogenase, zinc-binding dom... 77 4e-13
UniRef50_Q6BTK7 Cluster: Similar to sp|Q04894 Saccharomyces cere... 77 4e-13
UniRef50_Q0S6W9 Cluster: Zn-binding dehydrogenase; n=4; Actinomy... 76 6e-13
UniRef50_A5V690 Cluster: Alcohol dehydrogenase GroES domain prot... 76 6e-13
UniRef50_A5IYL7 Cluster: Alcohol dehydrogenase; n=2; Mycoplasma ... 76 6e-13
UniRef50_Q5K7P7 Cluster: (R,R)-butanediol dehydrogenase, putativ... 76 6e-13
UniRef50_P07246 Cluster: Alcohol dehydrogenase III, mitochondria... 76 6e-13
UniRef50_Q9A4J4 Cluster: Alcohol dehydrogenase, zinc-containing;... 76 7e-13
UniRef50_A6X5V4 Cluster: Alcohol dehydrogenase zinc-binding doma... 76 7e-13
UniRef50_Q5K773 Cluster: Alcohol dehydrogenase, putative; n=1; F... 76 7e-13
UniRef50_P77539 Cluster: Uncharacterized zinc-type alcohol dehyd... 76 7e-13
UniRef50_Q7UU62 Cluster: Sorbitol dehydrogenase; n=1; Pirellula ... 75 1e-12
UniRef50_Q2LXU3 Cluster: 6-hydroxycyclohex-1-ene-1-carboxyl-CoA ... 75 1e-12
UniRef50_Q0SJC5 Cluster: Zn-containing alcohol dehydrogenase; n=... 75 1e-12
UniRef50_A7BC76 Cluster: Putative uncharacterized protein; n=1; ... 75 1e-12
UniRef50_A0NJ16 Cluster: L-iditol 2-dehydrogenase; n=5; Bacteria... 75 1e-12
UniRef50_Q5KF98 Cluster: Alcohol dehydrogenase, putative; n=1; F... 75 1e-12
UniRef50_A0KRX9 Cluster: Alcohol dehydrogenase, zinc-binding dom... 75 1e-12
UniRef50_O67374 Cluster: Alcohol dehydrogenase; n=1; Aquifex aeo... 75 2e-12
UniRef50_Q1LNT3 Cluster: Alcohol dehydrogenase GroES-like protei... 75 2e-12
UniRef50_Q1J6P8 Cluster: Zn-dependent alcohol dehydrogenase; n=1... 75 2e-12
UniRef50_A7DNK0 Cluster: Alcohol dehydrogenase GroES domain prot... 75 2e-12
UniRef50_Q9KBH6 Cluster: BH1951 protein; n=1; Bacillus haloduran... 74 2e-12
UniRef50_Q1AU73 Cluster: Alcohol dehydrogenase, zinc-binding pro... 74 2e-12
UniRef50_A6WA66 Cluster: Alcohol dehydrogenase zinc-binding doma... 74 2e-12
UniRef50_Q08XA0 Cluster: Alcohol dehydrogenase; n=2; Cystobacter... 74 3e-12
UniRef50_Q66UT6 Cluster: NAD-and Zn-dependent alcohol dehydrogen... 74 3e-12
UniRef50_Q0CK29 Cluster: Putative uncharacterized protein; n=2; ... 74 3e-12
UniRef50_Q2JAT4 Cluster: Alcohol dehydrogenase, zinc-binding; n=... 73 4e-12
UniRef50_Q11VP8 Cluster: Zinc-type alcohol dehydrogenase; n=2; S... 73 4e-12
UniRef50_A5G4J1 Cluster: Alcohol dehydrogenase GroES domain prot... 73 4e-12
UniRef50_A6AJT3 Cluster: Alcohol dehydrogenase, zinc-containing;... 73 5e-12
UniRef50_Q1ATH1 Cluster: Alcohol dehydrogenase, zinc-binding pro... 73 7e-12
UniRef50_A5ZML1 Cluster: Putative uncharacterized protein; n=1; ... 73 7e-12
UniRef50_A0JVZ3 Cluster: Alcohol dehydrogenase GroES domain prot... 73 7e-12
UniRef50_A0JVV9 Cluster: Alcohol dehydrogenase GroES domain prot... 73 7e-12
UniRef50_A0FZB5 Cluster: Alcohol dehydrogenase, zinc-binding; n=... 73 7e-12
UniRef50_Q8J0P3 Cluster: Alcohol dehydrogenase; n=2; Pezizomycot... 73 7e-12
UniRef50_Q97BK9 Cluster: Alcohol dehydrogenase [ADH]; n=3; Therm... 73 7e-12
UniRef50_Q39MG8 Cluster: Zinc-containing alcohol dehydrogenase s... 72 9e-12
UniRef50_Q2G9N3 Cluster: Alcohol dehydrogenase, zinc-containing;... 72 9e-12
UniRef50_Q3WCL0 Cluster: Zinc-containing alcohol dehydrogenase s... 72 9e-12
UniRef50_Q96XE0 Cluster: NAD-dependent alcohol dehydrogenase; n=... 72 9e-12
UniRef50_P20368 Cluster: Alcohol dehydrogenase 1; n=9; Bacteria|... 72 9e-12
UniRef50_Q89Z65 Cluster: Putative zinc-type alcohol dehydrogenas... 72 1e-11
UniRef50_A1ICC4 Cluster: Putative uncharacterized protein; n=1; ... 72 1e-11
UniRef50_A2QUV3 Cluster: Contig An10c0010, complete genome; n=6;... 72 1e-11
UniRef50_A1CC26 Cluster: Alcohol dehydrogenase; n=4; cellular or... 72 1e-11
UniRef50_O28179 Cluster: Alcohol dehydrogenase, zinc-dependent; ... 72 1e-11
UniRef50_A0RXG2 Cluster: Zn-dependent alcohol dehydrogenase; n=2... 72 1e-11
UniRef50_Q1INA4 Cluster: Alcohol dehydrogenase, zinc-binding; n=... 71 2e-11
UniRef50_A5V832 Cluster: Alcohol dehydrogenase GroES domain prot... 71 2e-11
UniRef50_A7EYS9 Cluster: Putative uncharacterized protein; n=1; ... 71 2e-11
UniRef50_A6RPM4 Cluster: Putative uncharacterized protein; n=1; ... 71 2e-11
UniRef50_Q8ZW83 Cluster: Alcohol dehydrogenase; n=4; Pyrobaculum... 71 2e-11
UniRef50_Q8PYV2 Cluster: Glutathione-independent formaldehyde de... 71 2e-11
UniRef50_A3DNG0 Cluster: Alcohol dehydrogenase GroES domain prot... 71 2e-11
UniRef50_Q83GG5 Cluster: Zinc-type alcohol dehydrogenase; n=3; A... 71 2e-11
UniRef50_A5HNZ8 Cluster: Zn-dependent alcohol dehydrogenase; n=2... 71 2e-11
UniRef50_A0ADQ4 Cluster: Putative dehydrogenase; n=1; Streptomyc... 71 2e-11
UniRef50_Q8TTM5 Cluster: Zinc-binding alcohol dehydrogenase; n=3... 71 2e-11
UniRef50_Q6NC01 Cluster: Possible alcohol dehydrogenase class II... 71 3e-11
UniRef50_Q0SJ82 Cluster: Possible alcohol dehydrogenase; n=13; c... 71 3e-11
UniRef50_A7HEW5 Cluster: Alcohol dehydrogenase GroES domain prot... 71 3e-11
UniRef50_A1SI01 Cluster: Alcohol dehydrogenase GroES domain prot... 71 3e-11
UniRef50_Q5V607 Cluster: Zinc-binding dehydrogenase; n=5; Haloba... 71 3e-11
UniRef50_Q5HRD6 Cluster: Alcohol dehydrogenase; n=106; Bacteria|... 70 4e-11
UniRef50_Q9PCQ1 Cluster: NADP-alcohol dehydrogenase; n=1; Xylell... 70 5e-11
UniRef50_Q97NH4 Cluster: Alcohol dehydrogenase, zinc-containing;... 70 5e-11
UniRef50_Q8EVN7 Cluster: NADP-dependent alcohol dehydrogenase; n... 70 5e-11
UniRef50_A5V7S4 Cluster: Alcohol dehydrogenase, zinc-binding dom... 70 5e-11
UniRef50_A1X3A2 Cluster: Putative Zn-dependent dehydrogenase; n=... 70 5e-11
UniRef50_Q6KZL8 Cluster: Alcohol dehydrogenase; n=1; Picrophilus... 70 5e-11
UniRef50_O31186 Cluster: Alcohol dehydrogenase; n=105; cellular ... 70 5e-11
UniRef50_UPI0000384B5E Cluster: COG1063: Threonine dehydrogenase... 69 6e-11
UniRef50_Q6ACG5 Cluster: Alcohol dehydrogenase; n=1; Leifsonia x... 69 6e-11
UniRef50_Q6L743 Cluster: 2-deoxy-scyllo-inosamine dehydrogenase;... 69 6e-11
UniRef50_UPI000045C1D4 Cluster: COG1063: Threonine dehydrogenase... 69 8e-11
UniRef50_Q9A414 Cluster: Alcohol dehydrogenase class III; n=8; P... 69 8e-11
UniRef50_O06012 Cluster: NAD alcohol dehydrogenase; n=31; Bacter... 69 8e-11
UniRef50_Q01NE8 Cluster: Alcohol dehydrogenase GroES domain prot... 69 8e-11
UniRef50_A3PJU5 Cluster: Alcohol dehydrogenase GroES domain prot... 69 8e-11
UniRef50_A0H1E5 Cluster: Alcohol dehydrogenase, zinc-binding; n=... 69 8e-11
UniRef50_A0FSG8 Cluster: Alcohol dehydrogenase GroES-like; n=1; ... 69 8e-11
UniRef50_Q0W5A6 Cluster: Putative glucose 1-dehydrogenase; n=1; ... 69 8e-11
UniRef50_Q9WYD4 Cluster: Alcohol dehydrogenase, zinc-containing;... 69 1e-10
UniRef50_A3MVR8 Cluster: Alcohol dehydrogenase GroES domain prot... 69 1e-10
UniRef50_P77316 Cluster: Uncharacterized zinc-type alcohol dehyd... 69 1e-10
UniRef50_A5FWT0 Cluster: Alcohol dehydrogenase GroES domain prot... 68 1e-10
UniRef50_A0QZV9 Cluster: Alcohol dehydrogenase B; n=1; Mycobacte... 68 1e-10
UniRef50_Q46P08 Cluster: Zinc-containing alcohol dehydrogenase s... 68 2e-10
UniRef50_Q0K0E7 Cluster: Zinc-type alcohol dehydrogenase adhd; n... 68 2e-10
UniRef50_A1BBK6 Cluster: Alcohol dehydrogenase GroES domain prot... 68 2e-10
UniRef50_Q59KU9 Cluster: Potential butanediol dehydrogenase; n=3... 68 2e-10
UniRef50_Q9HTE3 Cluster: Glutathione-independent formaldehyde de... 68 2e-10
UniRef50_Q1ARB8 Cluster: Alcohol dehydrogenase, zinc-binding pro... 67 3e-10
UniRef50_Q01W47 Cluster: Alcohol dehydrogenase GroES domain prot... 67 3e-10
UniRef50_A4FB48 Cluster: Putative uncharacterized protein; n=1; ... 67 3e-10
UniRef50_Q4P3P9 Cluster: Putative uncharacterized protein; n=1; ... 67 3e-10
UniRef50_Q18IV0 Cluster: NADPH:quinone reductase; n=1; Haloquadr... 67 3e-10
UniRef50_A3HAS3 Cluster: Alcohol dehydrogenase GroES-like; n=2; ... 67 3e-10
UniRef50_A0RUX6 Cluster: Zn-dependent alcohol dehydrogenase; n=1... 67 3e-10
UniRef50_Q1GKP3 Cluster: Alcohol dehydrogenase GroES-like protei... 67 3e-10
UniRef50_P00331 Cluster: Alcohol dehydrogenase 2; n=22; Ascomyco... 67 3e-10
UniRef50_UPI000023EC5C Cluster: hypothetical protein FG03041.1; ... 66 5e-10
UniRef50_Q5KJW4 Cluster: Zinc-type alcohol dehydrogenase, putati... 66 5e-10
UniRef50_Q8R9L6 Cluster: Threonine dehydrogenase and related Zn-... 66 6e-10
UniRef50_A7R300 Cluster: Chromosome undetermined scaffold_469, w... 66 6e-10
UniRef50_Q2H9V9 Cluster: Putative uncharacterized protein; n=1; ... 66 6e-10
UniRef50_A1D1F8 Cluster: Alcohol dehydrogenase; n=3; Pezizomycot... 66 6e-10
UniRef50_Q97ZV3 Cluster: Alcohol dehydrogenase; n=7; Thermoprote... 66 6e-10
UniRef50_A3H5I8 Cluster: Alcohol dehydrogenase GroES-like; n=1; ... 66 6e-10
UniRef50_Q976Y8 Cluster: 344aa long hypothetical alcohol dehydro... 66 8e-10
UniRef50_Q7BKE4 Cluster: Predicted Zn-dependent alcohol dehydrog... 65 1e-09
UniRef50_A5VAQ2 Cluster: Alcohol dehydrogenase GroES domain prot... 65 1e-09
UniRef50_A1SI74 Cluster: Alcohol dehydrogenase, zinc-binding dom... 65 1e-09
UniRef50_A1RCH0 Cluster: Putative alcohol dehydrogenase; n=2; Ar... 65 1e-09
UniRef50_Q0UBV8 Cluster: Putative uncharacterized protein; n=2; ... 65 1e-09
UniRef50_A7EEB7 Cluster: Putative uncharacterized protein; n=1; ... 65 1e-09
UniRef50_Q5KW77 Cluster: Alcohol dehydrogenase; n=2; Geobacillus... 65 1e-09
UniRef50_A4AQN2 Cluster: Putative zinc-binding dehydrogenase; n=... 65 1e-09
UniRef50_A0QZI7 Cluster: Aryl-alcohol dehydrogenase; n=1; Mycoba... 65 1e-09
UniRef50_A0PM90 Cluster: Short-chain dehydrogenase Adh_1; n=3; M... 65 1e-09
UniRef50_Q5YR32 Cluster: Putative dehydrogenase; n=1; Nocardia f... 64 2e-09
UniRef50_Q0RZT6 Cluster: Probable alcohol dehydrogenase; n=2; Rh... 64 2e-09
UniRef50_A7FVI5 Cluster: Oxidoreductase, zinc-binding dehydrogen... 64 2e-09
UniRef50_A6RNK3 Cluster: NADP-dependent alcohol dehydrogenase; n... 64 2e-09
UniRef50_Q4J6T9 Cluster: NAD-dependent alcohol dehydrogenase; n=... 64 2e-09
UniRef50_Q70KF0 Cluster: 2-deoxy-scyllo-inosamine dehydrogenase;... 64 2e-09
UniRef50_Q8KKS7 Cluster: Putative L-iditol 2-dehydrogenase prote... 64 2e-09
UniRef50_Q47QG1 Cluster: Alcohol dehydrogenase class III; n=1; T... 64 2e-09
UniRef50_Q0S5T4 Cluster: Alcohol dehydrogenase; n=1; Rhodococcus... 64 2e-09
UniRef50_Q0SDC0 Cluster: Zn-binding alcohol dehydrogenase; n=1; ... 64 2e-09
UniRef50_A0DCB5 Cluster: Chromosome undetermined scaffold_45, wh... 64 2e-09
UniRef50_Q2UHG1 Cluster: Alcohol dehydrogenase; n=8; Dikarya|Rep... 64 2e-09
UniRef50_A6S0I2 Cluster: Putative uncharacterized protein; n=1; ... 64 2e-09
UniRef50_A1C7T1 Cluster: Alcohol dehydrogenase, zinc-containing;... 64 2e-09
UniRef50_P47734 Cluster: S-(hydroxymethyl)glutathione dehydrogen... 64 2e-09
UniRef50_Q8ES57 Cluster: NADP-dependent alcohol dehydrogenase; n... 64 3e-09
UniRef50_A7NMA5 Cluster: Alcohol dehydrogenase GroES domain prot... 64 3e-09
UniRef50_A1R1P7 Cluster: Alcohol dehydrogenase; n=1; Arthrobacte... 64 3e-09
UniRef50_A1K6Y3 Cluster: Putative alcohol dehydrogenase; n=1; Az... 64 3e-09
UniRef50_Q4P2L9 Cluster: Putative uncharacterized protein; n=1; ... 64 3e-09
UniRef50_A6RJU6 Cluster: Putative uncharacterized protein; n=2; ... 64 3e-09
UniRef50_UPI000023D8ED Cluster: hypothetical protein FG07318.1; ... 63 4e-09
UniRef50_Q8YNV3 Cluster: All4458 protein; n=7; Bacteria|Rep: All... 63 4e-09
UniRef50_Q3WAW5 Cluster: Zinc-containing alcohol dehydrogenase s... 63 4e-09
UniRef50_A6WBJ8 Cluster: Alcohol dehydrogenase GroES domain prot... 63 4e-09
UniRef50_A6WBA5 Cluster: Alcohol dehydrogenase GroES domain prot... 63 4e-09
UniRef50_A6TKR3 Cluster: Alcohol dehydrogenase, zinc-binding dom... 63 4e-09
UniRef50_Q4WKQ3 Cluster: Formaldehyde dehydrogenase, putative; n... 63 4e-09
UniRef50_A4QVF8 Cluster: Zinc-binding dehydrogenase; n=4; Pezizo... 63 4e-09
UniRef50_Q7NLF7 Cluster: Gll1167 protein; n=4; Bacteria|Rep: Gll... 63 6e-09
UniRef50_Q3W6B4 Cluster: Zinc-containing alcohol dehydrogenase s... 63 6e-09
UniRef50_Q09D01 Cluster: Glucose dehydrogenase Gcd; n=2; Cystoba... 63 6e-09
UniRef50_A4RTG9 Cluster: Predicted protein; n=2; Ostreococcus|Re... 63 6e-09
UniRef50_A6SRD0 Cluster: Putative uncharacterized protein; n=1; ... 63 6e-09
UniRef50_A4RNL2 Cluster: Putative uncharacterized protein; n=3; ... 63 6e-09
UniRef50_A4QUV6 Cluster: Putative uncharacterized protein; n=2; ... 63 6e-09
UniRef50_A1CIX6 Cluster: Alcohol dehydrogenase; n=3; Pezizomycot... 63 6e-09
UniRef50_Q89GJ2 Cluster: Bll6353 protein; n=2; Proteobacteria|Re... 62 7e-09
UniRef50_A0NL69 Cluster: Sorbitol dehydrogenase; n=2; Oenococcus... 62 7e-09
UniRef50_A1DJP7 Cluster: Alcohol dehydrogenase, putative; n=5; T... 62 7e-09
UniRef50_Q02972 Cluster: Probable mannitol dehydrogenase 2; n=12... 62 7e-09
UniRef50_A0LKI1 Cluster: Alcohol dehydrogenase GroES domain prot... 62 1e-08
UniRef50_Q97YM2 Cluster: Alcohol dehydrogenase; n=2; Sulfolobus ... 62 1e-08
UniRef50_Q82GR4 Cluster: Putative alcohol dehydrogenase; n=1; St... 62 1e-08
UniRef50_Q577J1 Cluster: Alcohol dehydrogenase, zinc-containing;... 62 1e-08
UniRef50_Q2W5C7 Cluster: Zn-dependent alcohol dehydrogenase; n=6... 62 1e-08
UniRef50_Q28K81 Cluster: Alcohol dehydrogenase zinc-binding; n=3... 62 1e-08
UniRef50_A7HFA6 Cluster: Alcohol dehydrogenase GroES domain prot... 62 1e-08
UniRef50_A1SJ83 Cluster: Alcohol dehydrogenase GroES domain prot... 62 1e-08
UniRef50_Q5B536 Cluster: Putative uncharacterized protein; n=1; ... 62 1e-08
UniRef50_A7F361 Cluster: Putative uncharacterized protein; n=1; ... 62 1e-08
UniRef50_A0RZ53 Cluster: Zn-dependent oxidoreductase; n=4; Therm... 62 1e-08
UniRef50_P14940 Cluster: Alcohol dehydrogenase; n=31; cellular o... 62 1e-08
UniRef50_Q0S7E4 Cluster: Possible alcohol dehydrogenase; n=2; No... 61 2e-08
UniRef50_A0IUR9 Cluster: Alcohol dehydrogenase, zinc-binding; n=... 61 2e-08
UniRef50_A3MWI2 Cluster: Alcohol dehydrogenase GroES domain prot... 61 2e-08
UniRef50_Q6BV88 Cluster: Debaryomyces hansenii chromosome C of s... 61 2e-08
UniRef50_Q2HBT9 Cluster: Putative uncharacterized protein; n=1; ... 61 2e-08
UniRef50_Q97YT7 Cluster: Alcohol dehydrogenase; n=2; Thermoprote... 61 2e-08
UniRef50_Q820H0 Cluster: Putative dehydrogenase; n=4; Actinomyce... 60 3e-08
UniRef50_A7DRK1 Cluster: Alcohol dehydrogenase GroES domain prot... 60 3e-08
UniRef50_P09347 Cluster: 5-exo-alcohol dehydrogenase; n=4; Prote... 60 3e-08
UniRef50_UPI000023CF80 Cluster: hypothetical protein FG00231.1; ... 60 4e-08
UniRef50_Q15TG4 Cluster: Alcohol dehydrogenase, zinc-binding; n=... 60 4e-08
UniRef50_Q028K3 Cluster: Alcohol dehydrogenase GroES domain prot... 60 4e-08
UniRef50_A7BDX1 Cluster: Putative uncharacterized protein; n=1; ... 60 4e-08
UniRef50_A2V8B3 Cluster: N-benzyl-3-pyrrolidinol dehydrogenase; ... 60 4e-08
UniRef50_A2QBA8 Cluster: Catalytic activity: an alcohol + NAD(+)... 60 4e-08
UniRef50_A7D2S0 Cluster: Alcohol dehydrogenase GroES domain prot... 60 4e-08
UniRef50_Q9RZE4 Cluster: Alcohol dehydrogenase, zinc-containing;... 60 5e-08
UniRef50_Q7NCG2 Cluster: Gll3017 protein; n=3; Cyanobacteria|Rep... 60 5e-08
UniRef50_Q47PU4 Cluster: Oxidoreductase; n=1; Thermobifida fusca... 60 5e-08
UniRef50_Q0RV69 Cluster: Alcohol dehydrogenase; n=21; Actinomyce... 60 5e-08
UniRef50_A4TAE2 Cluster: Alcohol dehydrogenase GroES domain prot... 60 5e-08
UniRef50_Q8ZVD9 Cluster: Alcohol dehydrogenase; n=3; Pyrobaculum... 60 5e-08
UniRef50_P54202 Cluster: Alcohol dehydrogenase 2; n=15; Pezizomy... 60 5e-08
UniRef50_P07327 Cluster: Alcohol dehydrogenase 1A; n=1281; cellu... 60 5e-08
UniRef50_Q0SJX5 Cluster: Alcohol dehydrogenase; n=11; Corynebact... 59 7e-08
UniRef50_Q84H90 Cluster: 6-hydroxyhexanoate dehydrogenase; n=3; ... 59 7e-08
UniRef50_Q11Z80 Cluster: Alcohol dehydrogenase, zinc-binding; n=... 59 7e-08
UniRef50_A0R799 Cluster: Alcohol dehydrogenase; n=3; Bacteria|Re... 59 7e-08
>UniRef50_O97479 Cluster: CG1982-PA; n=17; Bilateria|Rep: CG1982-PA
- Drosophila melanogaster (Fruit fly)
Length = 360
Score = 299 bits (734), Expect = 3e-80
Identities = 134/186 (72%), Positives = 156/186 (83%)
Frame = +3
Query: 42 MATDNLTALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEE 221
MA DNLTA+L+ D+RL Q PIPEI++DEVLL MD VGICGSDVHY G+ G FVL +
Sbjct: 1 MAKDNLTAVLHGIEDMRLEQRPIPEIADDEVLLAMDSVGICGSDVHYLAHGRIGDFVLTK 60
Query: 222 PMIMGHEASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPP 401
PMI+GHE++GVVAK+G KV L VGDRVAIEPGVPCR C+ CK G+Y+LCP M+FCATPP
Sbjct: 61 PMIIGHESAGVVAKLGKKVTTLKVGDRVAIEPGVPCRKCDHCKQGKYNLCPGMVFCATPP 120
Query: 402 VHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPI 581
GNL RYYKHAADFCFKLPDHVTMEEGALLEPL+VG+HACKR V+ G VL+LGAGPI
Sbjct: 121 YDGNLTRYYKHAADFCFKLPDHVTMEEGALLEPLSVGVHACKRAEVTLGSKVLILGAGPI 180
Query: 582 GLLTML 599
GL+T++
Sbjct: 181 GLVTLM 186
>UniRef50_Q00796 Cluster: Sorbitol dehydrogenase; n=35;
Eumetazoa|Rep: Sorbitol dehydrogenase - Homo sapiens
(Human)
Length = 357
Score = 267 bits (654), Expect = 2e-70
Identities = 118/183 (64%), Positives = 147/183 (80%)
Frame = +3
Query: 51 DNLTALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMI 230
+NL+ +++ P DLRL PIPE +EVLLRM VGICGSDVHYW+ G+ G+F++++PM+
Sbjct: 8 NNLSLVVHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMV 67
Query: 231 MGHEASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHG 410
+GHEASG V K+GS VK+L GDRVAIEPG P EFCK GRY+L P + FCATPP G
Sbjct: 68 LGHEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDG 127
Query: 411 NLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLL 590
NL R+YKH A FC+KLPD+VT EEGAL+EPL+VGIHAC+RGGV+ GH VLV GAGPIG++
Sbjct: 128 NLCRFYKHNAAFCYKLPDNVTFEEGALIEPLSVGIHACRRGGVTLGHKVLVCGAGPIGMV 187
Query: 591 TML 599
T+L
Sbjct: 188 TLL 190
>UniRef50_Q58D31 Cluster: Sorbitol dehydrogenase; n=8;
Eukaryota|Rep: Sorbitol dehydrogenase - Bos taurus
(Bovine)
Length = 356
Score = 260 bits (638), Expect = 1e-68
Identities = 116/183 (63%), Positives = 146/183 (79%)
Frame = +3
Query: 51 DNLTALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMI 230
+NL+ +++ P DLRL PIPE +EVLL+M VGICGSDVHYWQ G+ G FV+++PM+
Sbjct: 7 ENLSLVVHGPGDLRLENYPIPEPGPNEVLLKMHSVGICGSDVHYWQHGRIGDFVVKKPMV 66
Query: 231 MGHEASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHG 410
+GHEASG V K+GS V++L GDRVAIEPG P EFCK GRY+L P + FCATPP G
Sbjct: 67 LGHEASGTVVKVGSLVRHLQPGDRVAIEPGAPRETDEFCKIGRYNLSPTIFFCATPPDDG 126
Query: 411 NLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLL 590
NL R+YKH A+FC+KLPD+VT EEGAL+EPL+VGIHAC+R GV+ G+ VLV GAGPIGL+
Sbjct: 127 NLCRFYKHNANFCYKLPDNVTFEEGALIEPLSVGIHACRRAGVTLGNKVLVCGAGPIGLV 186
Query: 591 TML 599
++L
Sbjct: 187 SLL 189
>UniRef50_Q6PGX2 Cluster: Zgc:63674; n=2; Danio rerio|Rep: Zgc:63674
- Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 594
Score = 258 bits (632), Expect = 7e-68
Identities = 117/186 (62%), Positives = 144/186 (77%)
Frame = +3
Query: 42 MATDNLTALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEE 221
M DNL+ +L+ DLRL Q PIPE ++VLL+M VGICGSDVHYWQ G+ G FV+++
Sbjct: 1 MDKDNLSVVLHAKGDLRLEQRPIPEPGPNDVLLQMHSVGICGSDVHYWQNGRIGDFVVKQ 60
Query: 222 PMIMGHEASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPP 401
PMI+GHEASG V K+GS V +L GDRVA+EPGVP EF K+G Y+L P + FCATPP
Sbjct: 61 PMILGHEASGRVVKVGSAVTHLKPGDRVAVEPGVPREVDEFVKSGHYNLSPSIFFCATPP 120
Query: 402 VHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPI 581
GNL RYYKH+A FC+KLPD+VT EEGAL+EPL+VGIHAC+R GV+ G V V GAGPI
Sbjct: 121 DDGNLCRYYKHSASFCYKLPDNVTYEEGALIEPLSVGIHACRRAGVTLGSSVFVCGAGPI 180
Query: 582 GLLTML 599
GL+++L
Sbjct: 181 GLVSLL 186
>UniRef50_Q7QAQ4 Cluster: ENSANGP00000011378; n=3; Culicidae|Rep:
ENSANGP00000011378 - Anopheles gambiae str. PEST
Length = 362
Score = 241 bits (591), Expect = 7e-63
Identities = 108/182 (59%), Positives = 134/182 (73%)
Frame = +3
Query: 54 NLTALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIM 233
NL +++ D R+ + P+P + EVLL MDCVGICGSDVHY G G + L++ M++
Sbjct: 8 NLAGVVHGVEDFRVEEIPMPRPRDHEVLLEMDCVGICGSDVHYVSHGGFGDYKLKDKMVL 67
Query: 234 GHEASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGN 413
GHE+SGVV +G+ V +L VGDRVAIEP + CR C CK GRY++CP ++C T HGN
Sbjct: 68 GHESSGVVVAVGADVTSLQVGDRVAIEPAIGCRTCRHCKAGRYNICPQGVYCVTTG-HGN 126
Query: 414 LVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLLT 593
L YY HAAD CFKLP +VTMEEGALLEPLAVG+H C+RGGV G VLVLGAGPIGL+T
Sbjct: 127 LCNYYTHAADCCFKLPANVTMEEGALLEPLAVGVHCCRRGGVGIGSTVLVLGAGPIGLVT 186
Query: 594 ML 599
+L
Sbjct: 187 LL 188
>UniRef50_Q02912 Cluster: Sorbitol dehydrogenase; n=1; Bombyx
mori|Rep: Sorbitol dehydrogenase - Bombyx mori (Silk
moth)
Length = 348
Score = 239 bits (586), Expect = 3e-62
Identities = 100/181 (55%), Positives = 139/181 (76%)
Frame = +3
Query: 48 TDNLTALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPM 227
T+N A+L+ ND+R+ + P+PEI++DEVL+++DCVGICGSDV + G CG V+++P+
Sbjct: 2 TENYAAVLHGANDVRIEKIPVPEINDDEVLIKIDCVGICGSDVKLYSTGTCGADVIDKPI 61
Query: 228 IMGHEASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVH 407
++GHE +G V K+G KV +L VGDRVAIEP PCR CE CK G+Y+LC + +C++
Sbjct: 62 VIGHEGAGTVVKVGDKVSSLRVGDRVAIEPTQPCRSCELCKRGKYNLCVEPRYCSSMGAP 121
Query: 408 GNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGL 587
GNL RYYKH ADFC KLPD++TMEEGA ++PLA+ IHAC R ++ G +++LGAGPIG+
Sbjct: 122 GNLCRYYKHVADFCHKLPDNLTMEEGAAVQPLAIVIHACNRAKITLGSKIVILGAGPIGI 181
Query: 588 L 590
L
Sbjct: 182 L 182
>UniRef50_Q0TT56 Cluster: L-iditol 2-dehydrogenase; n=3;
Clostridiaceae|Rep: L-iditol 2-dehydrogenase -
Clostridium perfringens (strain ATCC 13124 / NCTC 8237 /
Type A)
Length = 348
Score = 226 bits (552), Expect = 4e-58
Identities = 95/169 (56%), Positives = 130/169 (76%)
Frame = +3
Query: 93 LVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGS 272
L++ IP + E+EVL+++D VGICGSD+HY++ G+ G +++E P ++GHE GVV ++G+
Sbjct: 18 LIERDIPIVKENEVLVKLDYVGICGSDLHYYENGRIGDYIVEPPFVLGHEPGGVVVEVGN 77
Query: 273 KVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCF 452
KVK+L +GDRVA+EPG C +CEFCKTGRY+LCPD+IF ATPPV G Y H AD CF
Sbjct: 78 KVKHLNIGDRVALEPGKTCGHCEFCKTGRYNLCPDVIFFATPPVDGVFQEYVAHEADLCF 137
Query: 453 KLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLLTML 599
KLP++V+ EGAL+EPLAVG HA +GG G +V+GAG IGL++M+
Sbjct: 138 KLPENVSTLEGALIEPLAVGFHAAIQGGARIGQTAVVMGAGCIGLVSMM 186
>UniRef50_Q67XB8 Cluster: Sorbitol dehydrogenase-like protein; n=41;
Magnoliophyta|Rep: Sorbitol dehydrogenase-like protein -
Arabidopsis thaliana (Mouse-ear cress)
Length = 364
Score = 224 bits (548), Expect = 1e-57
Identities = 98/188 (52%), Positives = 135/188 (71%)
Frame = +3
Query: 36 SDMATDNLTALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVL 215
S + +N+ A L N L++ +P + +V +RM VGICGSDVHY + C FV+
Sbjct: 12 SKVEEENMAAWLVGINTLKIQPFLLPSVGPHDVRVRMKAVGICGSDVHYLKTMICADFVV 71
Query: 216 EEPMIMGHEASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCAT 395
+EPM++GHE +G++ ++G +VK+L VGDRVA+EPG+ C C C+ GRY+LCP+M F AT
Sbjct: 72 KEPMVIGHECAGIIEEVGEEVKHLVVGDRVALEPGISCWRCNLCREGRYNLCPEMKFFAT 131
Query: 396 PPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAG 575
PPVHG+L H AD CFKLP++V++EEGA+ EPL+VG+HAC+R V VLV+GAG
Sbjct: 132 PPVHGSLANQVVHPADLCFKLPENVSLEEGAMCEPLSVGVHACRRAEVGPETNVLVMGAG 191
Query: 576 PIGLLTML 599
PIGL+TML
Sbjct: 192 PIGLVTML 199
>UniRef50_A1CFY8 Cluster: Xylitol dehydrogenase; n=22;
Ascomycota|Rep: Xylitol dehydrogenase - Aspergillus
clavatus
Length = 380
Score = 222 bits (542), Expect = 6e-57
Identities = 94/180 (52%), Positives = 132/180 (73%), Gaps = 1/180 (0%)
Frame = +3
Query: 54 NLTALLYKPNDLRLVQTPIPEISED-EVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMI 230
NL+ +L + ++ PIPE+ + +V++ + GICGSDVHYW+ G GHFV+++PM+
Sbjct: 32 NLSFVLEGIHQVKFEDRPIPELRDPHDVIVNVKYTGICGSDVHYWEHGAIGHFVVKDPMV 91
Query: 231 MGHEASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHG 410
+GHE+SGVVAK+GS V +L VGDRVA+EPGVPCR CE CK G+Y+LC M F ATPP G
Sbjct: 92 LGHESSGVVAKVGSAVTSLKVGDRVAMEPGVPCRRCEPCKAGKYNLCEKMAFAATPPYDG 151
Query: 411 NLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLL 590
L +YY DFC+KLP++++++EGAL+EPL V +H ++ + G V+V GAGP+GLL
Sbjct: 152 TLAKYYPLPEDFCYKLPENISLQEGALMEPLGVAVHITRQASIKPGESVVVFGAGPVGLL 211
>UniRef50_UPI0000E46CC1 Cluster: PREDICTED: similar to SORD protein;
n=3; Strongylocentrotus purpuratus|Rep: PREDICTED:
similar to SORD protein - Strongylocentrotus purpuratus
Length = 292
Score = 221 bits (539), Expect = 1e-56
Identities = 99/178 (55%), Positives = 125/178 (70%)
Frame = +3
Query: 39 DMATDNLTALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLE 218
D+ + A+L D+++ Q + +EVLL + VGICGSD+ YW G CG F L
Sbjct: 2 DLPKETQCAVLCGIKDIKMEQRSVTAPGPNEVLLAVHSVGICGSDLKYWSHGYCGRFKLT 61
Query: 219 EPMIMGHEASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATP 398
PM++GHEASG VA +G VK+L VGDRVAIEPGVPCR C C+ G+Y+LC D+ FCATP
Sbjct: 62 APMVIGHEASGTVAALGPGVKHLEVGDRVAIEPGVPCRMCSLCRVGKYNLCRDVQFCATP 121
Query: 399 PVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGA 572
PV GNL +YY HAADFCFKLP +V+ EEGAL+EPLAV ++ C R VS G VL+ G+
Sbjct: 122 PVDGNLSQYYLHAADFCFKLPSNVSYEEGALVEPLAVALYTCSRAEVSLGSKVLICGS 179
>UniRef50_Q16R00 Cluster: Alcohol dehydrogenase; n=3; Culicidae|Rep:
Alcohol dehydrogenase - Aedes aegypti (Yellowfever
mosquito)
Length = 364
Score = 215 bits (524), Expect = 9e-55
Identities = 96/183 (52%), Positives = 131/183 (71%)
Frame = +3
Query: 51 DNLTALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMI 230
+NL AL+Y PNDLRL PIPE + +EV++ +D GICG+D+H+ + G G L +P++
Sbjct: 6 ENLCALVYGPNDLRLEPRPIPEPAFNEVVVEVDSCGICGTDIHFLKDGGFGAQRLIKPIV 65
Query: 231 MGHEASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHG 410
+GHE++GVV K+GS+V NL VGDRVAIEP CR C+ CK G+Y++C D C T G
Sbjct: 66 LGHESAGVVRKVGSQVTNLKVGDRVAIEPAAGCRTCDLCKVGKYNICLDGKHCTTQKHDG 125
Query: 411 NLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLL 590
N YY AD CFK+PDH+TMEEGALLEPLAV ++A +R + G+ V++ GAGPIGL+
Sbjct: 126 NCSNYYAQYADCCFKMPDHMTMEEGALLEPLAVAVYAGRRAQIGLGNKVVIFGAGPIGLV 185
Query: 591 TML 599
++
Sbjct: 186 CLI 188
>UniRef50_A3TNY9 Cluster: Zinc-binding dehydrogenase; n=5;
Actinomycetales|Rep: Zinc-binding dehydrogenase -
Janibacter sp. HTCC2649
Length = 355
Score = 208 bits (509), Expect = 6e-53
Identities = 90/176 (51%), Positives = 123/176 (69%)
Frame = +3
Query: 63 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 242
A+L +P + + P+P + DEVL+ + VG+CGSD HY+ G+ G ++ PM++GHE
Sbjct: 13 AVLAEPGSIVMETRPVPSPAADEVLIEVRSVGVCGSDTHYFDHGRIGEHIVTGPMVLGHE 72
Query: 243 ASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVR 422
++GV+ +GS V +G+RVAIEPGVPCR C C G Y+LCPDM+F ATPP+ G L
Sbjct: 73 SAGVIVGVGSGVDPARIGERVAIEPGVPCRSCAQCLAGHYNLCPDMVFHATPPIDGTLAE 132
Query: 423 YYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLL 590
Y H + F F LPD V+++EGA+LEPL+VGI AC+R GV+ G VLV GAGP+G L
Sbjct: 133 YVVHPSSFAFALPDSVSLDEGAMLEPLSVGIWACRRAGVAPGVRVLVTGAGPVGQL 188
>UniRef50_Q5V6U8 Cluster: Zinc-binding dehydrogenase; n=1;
Haloarcula marismortui|Rep: Zinc-binding dehydrogenase -
Haloarcula marismortui (Halobacterium marismortui)
Length = 343
Score = 208 bits (508), Expect = 8e-53
Identities = 92/179 (51%), Positives = 121/179 (67%)
Frame = +3
Query: 60 TALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGH 239
TA+L +P + L P P DEVL+ + VGICGSDVHY++ G+ G +V+E+P+++GH
Sbjct: 3 TAVLVEPTEFELEDRPRPSPGPDEVLVAVRDVGICGSDVHYYEHGRIGDYVVEDPLVLGH 62
Query: 240 EASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLV 419
E++G V ++G V + GDRVA+EPGVPCR C CK G YHLC + F ATPP G
Sbjct: 63 ESAGKVVEVGENVTDHEPGDRVALEPGVPCRRCAHCKRGDYHLCESVRFMATPPHDGAFT 122
Query: 420 RYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLLTM 596
Y ADF + LP+ V+ EGAL EPL+VGIHAC+RG V G VL+ GAGPIGL+ +
Sbjct: 123 EYVSWPADFAYTLPESVSTAEGALCEPLSVGIHACRRGSVGTGDTVLITGAGPIGLMVL 181
>UniRef50_Q06004 Cluster: Sorbitol dehydrogenase; n=5;
Bacillales|Rep: Sorbitol dehydrogenase - Bacillus
subtilis
Length = 353
Score = 207 bits (506), Expect = 1e-52
Identities = 86/178 (48%), Positives = 126/178 (70%)
Frame = +3
Query: 63 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 242
A+++ ++++ P+P+I+ DEVL+++ VGICGSD+HY+ G+ G++V+E+P I+GHE
Sbjct: 12 AVMHNTREIKIETLPVPDINHDEVLIKVMAVGICGSDLHYYTNGRIGNYVVEKPFILGHE 71
Query: 243 ASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVR 422
+G +A +GS V VGDRVA+EPGV C CE CK GRY+LCPD+ F ATPPV G V+
Sbjct: 72 CAGEIAAVGSSVDQFKVGDRVAVEPGVTCGRCEACKEGRYNLCPDVQFLATPPVDGAFVQ 131
Query: 423 YYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLLTM 596
Y K DF F +PD ++ EE AL+EP +VGIHA R + G + ++G GP+GL+ +
Sbjct: 132 YIKMRQDFVFLIPDSLSYEEAALIEPFSVGIHAAARTKLQPGSTIAIMGMGPVGLMAV 189
>UniRef50_Q1J2J1 Cluster: Alcohol dehydrogenase GroES-like; n=1;
Deinococcus geothermalis DSM 11300|Rep: Alcohol
dehydrogenase GroES-like - Deinococcus geothermalis
(strain DSM 11300)
Length = 359
Score = 202 bits (494), Expect = 4e-51
Identities = 96/186 (51%), Positives = 121/186 (65%)
Frame = +3
Query: 39 DMATDNLTALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLE 218
D + + ++L+ DLR +P EV +R+ VG+CGSDVHY+ G+ G FV+E
Sbjct: 5 DSSLSSRISVLHGIRDLRWETREVPAPGPREVRVRVRRVGVCGSDVHYYTHGRIGSFVVE 64
Query: 219 EPMIMGHEASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATP 398
P+I+GHE GVV +G V ++ GDRVA+EPGVPCR C FCK G Y+LCPDM F ATP
Sbjct: 65 APLILGHEVMGVVDAVGEGVTHVRPGDRVALEPGVPCRRCAFCKRGEYNLCPDMTFMATP 124
Query: 399 PVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGP 578
PVHG L Y DF F LPD ++ + GALLEPLAVGI A ++G V G V V GAGP
Sbjct: 125 PVHGALGEYVLWPDDFAFLLPDRISDDAGALLEPLAVGIWAARKGDVRPGQSVAVFGAGP 184
Query: 579 IGLLTM 596
IG T+
Sbjct: 185 IGCTTL 190
>UniRef50_Q5KPZ2 Cluster: Sorbitol dehydrogenase, putative; n=1;
Filobasidiella neoformans|Rep: Sorbitol dehydrogenase,
putative - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 379
Score = 202 bits (492), Expect = 7e-51
Identities = 97/193 (50%), Positives = 130/193 (67%), Gaps = 5/193 (2%)
Frame = +3
Query: 33 ASDMATDNLTALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFV 212
++++ DN + +L+ D+R Q PIPE+ D+VL+++ GICGSDVHY Q G+ G FV
Sbjct: 2 STELNPDNTSFVLHGVEDVRFDQRPIPEVHNDQVLIKVVKTGICGSDVHYLQHGRIGSFV 61
Query: 213 LEEPMIMGHEASGVVAKIGSKVK---NLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMI 383
LEEPM +GHE++GVV K+G V+ + VG RVA+EPGV CR C CK G Y LCP M
Sbjct: 62 LEEPMCLGHESAGVVVKLGPNVREDLGVEVGTRVAMEPGVCCRSCANCKAGLYELCPYMS 121
Query: 384 FCATPP-VHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHA-CKRGGVSAGHVV 557
F ATPP + G L RYY AD LP+ V+ E+GA++EPL+VG+H+ GG + V
Sbjct: 122 FAATPPTIFGTLCRYYVLPADLVHPLPESVSFEDGAMMEPLSVGVHSVATLGGCKSDQTV 181
Query: 558 LVLGAGPIGLLTM 596
+V GAGP+GLL M
Sbjct: 182 IVFGAGPVGLLCM 194
>UniRef50_Q07786 Cluster: Sorbitol dehydrogenase 2; n=8;
Saccharomycetales|Rep: Sorbitol dehydrogenase 2 -
Saccharomyces cerevisiae (Baker's yeast)
Length = 357
Score = 200 bits (489), Expect = 2e-50
Identities = 93/181 (51%), Positives = 122/181 (67%), Gaps = 1/181 (0%)
Frame = +3
Query: 54 NLTALLYKPNDLRLVQTPIPEISEDE-VLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMI 230
N +L K D+ + Q PIP I + V L + GICGSD+HY++ G G ++L+ PM+
Sbjct: 6 NPAVVLEKVGDIAIEQRPIPTIKDPHYVKLAIKATGICGSDIHYYRSGGIGKYILKAPMV 65
Query: 231 MGHEASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHG 410
+GHE+SG V ++G V + VGDRVAIEPGVP RY + K G Y+LCP M F ATPP+ G
Sbjct: 66 LGHESSGQVVEVGDAVTRVKVGDRVAIEPGVPSRYSDETKEGSYNLCPHMAFAATPPIDG 125
Query: 411 NLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLL 590
LV+YY DF KLP+ V+ EEGA +EPL+VG+H+ K GV G V+V GAGP+GLL
Sbjct: 126 TLVKYYLSPEDFLVKLPEGVSYEEGACVEPLSVGVHSNKLAGVRFGTKVVVFGAGPVGLL 185
Query: 591 T 593
T
Sbjct: 186 T 186
>UniRef50_Q4WT02 Cluster: Xylitol dehydrogenase; n=8;
Pezizomycotina|Rep: Xylitol dehydrogenase - Aspergillus
fumigatus (Sartorya fumigata)
Length = 383
Score = 200 bits (488), Expect = 2e-50
Identities = 82/165 (49%), Positives = 118/165 (71%), Gaps = 1/165 (0%)
Frame = +3
Query: 99 QTPIPEI-SEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGSK 275
+ P P+I SE +V++R+ G+CGSDVHYWQ G+ G + + P+++GHE+SGV+ GS
Sbjct: 43 ERPTPKIESERDVIVRVVATGLCGSDVHYWQHGRIGRYAVNRPIVLGHESSGVIVACGSN 102
Query: 276 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFK 455
V L VGDRVA+EPG+ C C++C++G Y+LC M+F ATPP G L +YK A+ C+K
Sbjct: 103 VDGLKVGDRVALEPGISCNTCKYCRSGHYNLCKSMVFAATPPYDGTLSTFYKVPAECCYK 162
Query: 456 LPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLL 590
LP H+++ +GAL+EPL+V +HAC+ G V+V GAGP+GLL
Sbjct: 163 LPVHISLRDGALVEPLSVAVHACRLAGDMQNKSVVVFGAGPVGLL 207
>UniRef50_P36624 Cluster: Putative sorbitol dehydrogenase; n=1;
Schizosaccharomyces pombe|Rep: Putative sorbitol
dehydrogenase - Schizosaccharomyces pombe (Fission
yeast)
Length = 360
Score = 198 bits (483), Expect = 8e-50
Identities = 89/186 (47%), Positives = 123/186 (66%), Gaps = 1/186 (0%)
Frame = +3
Query: 42 MATDNLTALLYKPNDLRLVQTPIPEISED-EVLLRMDCVGICGSDVHYWQKGQCGHFVLE 218
MA +L K D + P +++D +V + + GICGSDVHYW++G G F+L+
Sbjct: 1 MAPAEKAFVLRKKMDTAIEDRPGQTLTDDHQVKVAIKATGICGSDVHYWKEGGIGDFILK 60
Query: 219 EPMIMGHEASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATP 398
+PMI+GHE++GVV ++G V +L GD VA+EPG CR C++C++GRY+LCP M F ATP
Sbjct: 61 KPMILGHESAGVVVEVGKGVSSLKPGDPVAVEPGCVCRLCDYCRSGRYNLCPHMEFAATP 120
Query: 399 PVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGP 578
P G L YY DFC KLP +++EEGAL EP++V +HA RG + G VLV+G G
Sbjct: 121 PYDGTLRTYYITTEDFCTKLPKQISVEEGALFEPMSVAVHAMTRGNLKCGSRVLVMGCGT 180
Query: 579 IGLLTM 596
+GLL M
Sbjct: 181 VGLLMM 186
>UniRef50_A5AB83 Cluster: Contig An08c0230, complete genome; n=9;
Ascomycota|Rep: Contig An08c0230, complete genome -
Aspergillus niger
Length = 387
Score = 193 bits (470), Expect = 3e-48
Identities = 88/180 (48%), Positives = 123/180 (68%), Gaps = 1/180 (0%)
Frame = +3
Query: 54 NLTALLYKPNDLRLVQTPIPEISED-EVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMI 230
N + +L+ D+ P+P + + +V + + GICGSDVHYWQ+G+ G F+L+ P++
Sbjct: 35 NRSFVLHAIKDVVFEDRPVPALKDPWDVRVHIAQTGICGSDVHYWQRGRIGDFILKSPIV 94
Query: 231 MGHEASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHG 410
+GHE+SG V ++GS VKN+ VG+RVAIEPGVPCR+ G Y+LCPD IF ATPP G
Sbjct: 95 LGHESSGTVVEVGSAVKNVKVGERVAIEPGVPCRH------GSYNLCPDTIFAATPPHDG 148
Query: 411 NLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLL 590
L +YY AD+C+ LP+++ +EEGAL+EP+AV + K G V V+V G GPIGLL
Sbjct: 149 TLSKYYTTQADYCYPLPENMDLEEGALVEPVAVAVQITKVGKVKPNQTVVVFGCGPIGLL 208
>UniRef50_Q4WT03 Cluster: L-arabinitol 4-dehydrogenase; n=5;
Trichocomaceae|Rep: L-arabinitol 4-dehydrogenase -
Aspergillus fumigatus (Sartorya fumigata)
Length = 359
Score = 190 bits (462), Expect = 3e-47
Identities = 83/175 (47%), Positives = 119/175 (68%), Gaps = 2/175 (1%)
Frame = +3
Query: 81 NDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVA 260
+DLRLV+ IP++ DE L+ + GICGSDVH+W+ G+ G ++ +GHE++GVV
Sbjct: 19 HDLRLVECEIPKLRPDECLVHVRATGICGSDVHFWKHGRIGPMIVTGDNGLGHESAGVVL 78
Query: 261 KIGSKVKNLTVGDRVAIEPGVPCRY--CEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKH 434
+IG V GDRVA+E GVPC C FC+TG+YH CPD++F +TPP HG L RY+ H
Sbjct: 79 QIGEAVTRFKPGDRVALECGVPCSKPTCSFCRTGKYHACPDVVFFSTPPHHGTLRRYHAH 138
Query: 435 AADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLLTML 599
+ K+PD+++ EEG+LLEPL+V + R G+ +++ GAGPIGL+T+L
Sbjct: 139 PEAWLHKIPDNISFEEGSLLEPLSVALAGINRSGLRLADPLVICGAGPIGLITLL 193
>UniRef50_P22144 Cluster: D-xylulose reductase; n=8;
Saccharomycetales|Rep: D-xylulose reductase - Pichia
stipitis (Yeast)
Length = 363
Score = 189 bits (460), Expect = 5e-47
Identities = 92/189 (48%), Positives = 127/189 (67%), Gaps = 8/189 (4%)
Frame = +3
Query: 48 TDNLTALLYKPNDLRLVQTPIPEISED-EVLLRMDCVGICGSDVHYWQKGQCGHFVLEEP 224
T N + +L K +D+ PEISE +VL+++ GICGSD+H++ G+ G+FVL +P
Sbjct: 2 TANPSLVLNKIDDISFETYDAPEISEPTDVLVQVKKTGICGSDIHFYAHGRIGNFVLTKP 61
Query: 225 MIMGHEASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPV 404
M++GHE++G V ++G V +L VGD VAIEPG+P R+ + K+G Y+LCP M F ATP
Sbjct: 62 MVLGHESAGTVVQVGKGVTSLKVGDNVAIEPGIPSRFSDEYKSGHYNLCPHMAFAATPNS 121
Query: 405 H-------GNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLV 563
G L +Y+K DF KLPDHV++E GAL+EPL+VG+HA K G V+ G V V
Sbjct: 122 KEGEPNPPGTLCKYFKSPEDFLVKLPDHVSLELGALVEPLSVGVHASKLGSVAFGDYVAV 181
Query: 564 LGAGPIGLL 590
GAGP+GLL
Sbjct: 182 FGAGPVGLL 190
>UniRef50_A1DBH5 Cluster: Alcohol dehydrogenase; n=3;
Pezizomycotina|Rep: Alcohol dehydrogenase - Neosartorya
fischeri (strain ATCC 1020 / DSM 3700 / NRRL
181)(Aspergillus fischerianus (strain ATCC 1020 / DSM
3700 / NRRL 181))
Length = 386
Score = 187 bits (455), Expect = 2e-46
Identities = 87/183 (47%), Positives = 119/183 (65%), Gaps = 4/183 (2%)
Frame = +3
Query: 54 NLTALLYKPNDLRLVQTPIPEISE-DEVLLRMDCVGICGSDVHYWQKGQCGHFV-LEEPM 227
N + LLY P D R PIP+I + +V++R+ G+CGSDVH+W G V E P+
Sbjct: 11 NPSCLLYGPFDARFEDRPIPQIEDPSDVIIRIAYTGVCGSDVHFWLHGGVKRLVSAEHPI 70
Query: 228 IMGHEASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPP-V 404
+MGHEASG+V +G V L GD +AIEPG PC C CK+GRY+LCP M F A PP
Sbjct: 71 VMGHEASGIVHAVGPSVSTLQPGDHIAIEPGYPCHRCPCCKSGRYNLCPRMKFAAAPPSC 130
Query: 405 HGNLVRYYKHAADFCFKL-PDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPI 581
HG L +Y++ AD+C+K+ P + ++E L+EPLAV +H+ ++ GV G V+V GAG +
Sbjct: 131 HGTLTKYFRLPADYCYKIPPGTLGLDEAVLMEPLAVAVHSVRQVGVRPGDRVVVFGAGTV 190
Query: 582 GLL 590
GLL
Sbjct: 191 GLL 193
>UniRef50_Q5K981 Cluster: L-iditol 2-dehydrogenase, putative; n=6;
Basidiomycota|Rep: L-iditol 2-dehydrogenase, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 400
Score = 184 bits (448), Expect = 1e-45
Identities = 85/185 (45%), Positives = 122/185 (65%), Gaps = 3/185 (1%)
Frame = +3
Query: 54 NLTALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGH-FVLEEPMI 230
NL + ++++++ PIP+ +DEV++ + GICGSDVH+W+ GQ G ++ +
Sbjct: 52 NLACAYDEKHNVKMINKPIPKARQDEVVVHIKATGICGSDVHFWKHGQIGPTMIVTDTCG 111
Query: 231 MGHEASGVVAKIGSKVKNLTVGDRVAIEPGVPCRY--CEFCKTGRYHLCPDMIFCATPPV 404
GHE++G V ++G V+ VGDRVAIE GVPC C C TGRY+ CP ++F +TPP
Sbjct: 112 AGHESAGEVVEVGPGVEQWKVGDRVAIECGVPCGQASCGPCVTGRYNACPQVVFFSTPPY 171
Query: 405 HGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIG 584
HG L RY+ H A + +LPD+++ EEGAL EP AV + A +R G G VL+ GAGPIG
Sbjct: 172 HGTLTRYHAHPASWLHRLPDNLSYEEGALCEPFAVALAALERAGNRLGDPVLICGAGPIG 231
Query: 585 LLTML 599
L+T+L
Sbjct: 232 LVTLL 236
>UniRef50_A3Q0B6 Cluster: Alcohol dehydrogenase GroES domain
protein; n=4; Actinomycetales|Rep: Alcohol dehydrogenase
GroES domain protein - Mycobacterium sp. (strain JLS)
Length = 341
Score = 182 bits (444), Expect = 4e-45
Identities = 82/168 (48%), Positives = 113/168 (67%)
Frame = +3
Query: 87 LRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKI 266
LR+ + P+P EVL+ + VG+CGSDVHY++ G+ G FV+EEPMI+GHE SG +A +
Sbjct: 20 LRIEERPVPSPGPHEVLVEVAAVGVCGSDVHYYRHGRIGDFVVEEPMILGHELSGRIAAV 79
Query: 267 GSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADF 446
G V VG+RVA+EP PCR C+ CK GRY+LCP+M F ATPP+ G RY DF
Sbjct: 80 GEGVDPGRVGERVAVEPQHPCRRCKQCKAGRYNLCPEMKFYATPPIDGAFCRYVVIDDDF 139
Query: 447 CFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLL 590
+P+ ++ + ALLEPL+V I ++ GV G +L+ GAGPIG++
Sbjct: 140 AHPVPESMSDDAAALLEPLSVAIATMRKAGVVPGSTILIAGAGPIGVI 187
>UniRef50_Q0U204 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 377
Score = 175 bits (426), Expect = 7e-43
Identities = 83/187 (44%), Positives = 119/187 (63%), Gaps = 8/187 (4%)
Frame = +3
Query: 54 NLTALLYKPNDLRLVQTPIPEISE-DEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEP-M 227
N + +LY + +L + P+PE+S+ + V++R+ VG+CGSDVH++ G G V +
Sbjct: 12 NPSIVLYGAKNAKLEERPVPELSDPNNVIVRIAYVGVCGSDVHFYTHGGIGRSVDPSTGL 71
Query: 228 IMGHEASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCA----- 392
MGHEASG + +G V + +GDRVAIEPG PCR C CK+G Y+LC M+F A
Sbjct: 72 TMGHEASGTITSVGPSVTSFKIGDRVAIEPGTPCRRCAACKSGTYNLCRHMLFAAAPGPP 131
Query: 393 -TPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLG 569
TP G L ++Y+ A D C+ +PD ++++E L+EPLAV +HA K G V G V+V+G
Sbjct: 132 STPGTPGTLSKFYEMAEDLCYVIPDAISLQEAVLVEPLAVAVHAVKLGDVRPGETVVVMG 191
Query: 570 AGPIGLL 590
G IGLL
Sbjct: 192 CGTIGLL 198
>UniRef50_Q1QUA2 Cluster: Alcohol dehydrogenase, zinc-binding; n=6;
cellular organisms|Rep: Alcohol dehydrogenase,
zinc-binding - Chromohalobacter salexigens (strain DSM
3043 / ATCC BAA-138 / NCIMB13768)
Length = 348
Score = 174 bits (424), Expect = 1e-42
Identities = 84/179 (46%), Positives = 116/179 (64%), Gaps = 1/179 (0%)
Frame = +3
Query: 66 LLYKPNDLRLVQTPIPE-ISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 242
+L K +L L +P+ + D+V +R+ VGICGSDVHY+ G+ G FV+ EPM++GHE
Sbjct: 7 VLEKQRELSLRDIDLPDQLGPDDVRIRIHTVGICGSDVHYYTHGRIGPFVVREPMVLGHE 66
Query: 243 ASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVR 422
ASGV+ ++GS V +L VG+RV +EPG+P K G Y++ P + F ATPPVHG L
Sbjct: 67 ASGVITEVGSHVSHLKVGERVCMEPGIPDPTSRAAKLGVYNVDPGVRFWATPPVHGCLTP 126
Query: 423 YYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLLTML 599
H A F F LPD V+ EGA++EP A+G+ A + + G V +V GAGPIGL+ L
Sbjct: 127 EVIHPAAFTFALPDSVSFAEGAMIEPFAIGMQAVVKARMQPGDVCVVTGAGPIGLMVAL 185
>UniRef50_Q59545 Cluster: D-xylulose reductase; n=36; Bacteria|Rep:
D-xylulose reductase - Morganella morganii (Proteus
morganii)
Length = 338
Score = 172 bits (419), Expect = 5e-42
Identities = 77/159 (48%), Positives = 111/159 (69%)
Frame = +3
Query: 117 ISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGSKVKNLTVG 296
+ +D+V +++ VGICGSDVHY+Q G+ G FV++EPM++GHEASGV+ G VK+L VG
Sbjct: 25 LGDDDVEIKIHTVGICGSDVHYYQHGRIGPFVVDEPMVLGHEASGVITAAGKNVKHLKVG 84
Query: 297 DRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTM 476
DRV +EPG+P + G Y+L P + F ATPP+ G L H A F FKLPD+V+
Sbjct: 85 DRVCMEPGIPDLQSPQSRAGIYNLDPAVRFWATPPIDGCLRESVIHPAAFTFKLPDNVSF 144
Query: 477 EEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLLT 593
+GA++EPLA+G+ + + G+ G + LV+GAG IG++T
Sbjct: 145 AQGAMVEPLAIGMQSATKAGIKPGDIGLVIGAGTIGIIT 183
>UniRef50_Q5WJ77 Cluster: Sorbitol dehydrogenase; n=1; Bacillus
clausii KSM-K16|Rep: Sorbitol dehydrogenase - Bacillus
clausii (strain KSM-K16)
Length = 346
Score = 172 bits (418), Expect = 6e-42
Identities = 71/171 (41%), Positives = 113/171 (66%)
Frame = +3
Query: 87 LRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKI 266
+ L + P+ EVL++M VGICGSD+HY++ G+ G V + P ++GHE +GVV K+
Sbjct: 12 IELEERTKPKPGAGEVLIQMKAVGICGSDLHYYEHGRIGERVAKPPFVLGHECAGVVTKV 71
Query: 267 GSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADF 446
G +V +L VGD V IEPG+PC C C+ G Y+LCP ++F ++PP G L+ Y H A F
Sbjct: 72 GPEVADLNVGDHVVIEPGLPCGECSSCRVGHYNLCPKVLFLSSPPNDGVLMEYICHPAKF 131
Query: 447 CFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLLTML 599
+K+P+ ++ E +L EPL+VG++ ++ + G ++++G GP+GL +L
Sbjct: 132 TYKMPEGLSFELASLAEPLSVGLYTAQKTSIQPGSNIVIMGMGPVGLCMIL 182
>UniRef50_Q98D10 Cluster: Putative D-xylulose reductase; n=9;
cellular organisms|Rep: Putative D-xylulose reductase -
Rhizobium loti (Mesorhizobium loti)
Length = 348
Score = 171 bits (417), Expect = 8e-42
Identities = 79/179 (44%), Positives = 114/179 (63%), Gaps = 1/179 (0%)
Frame = +3
Query: 66 LLYKPNDLRLVQTPIP-EISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 242
+L K +L L + +P ++ D+V + + VG+CGSDVHY+ G G +V+ PM++GHE
Sbjct: 5 VLEKKGELSLREIALPLDVGPDDVKIAIHTVGVCGSDVHYYTHGAIGSYVVRAPMVLGHE 64
Query: 243 ASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVR 422
A+G V + G+ V+ GDRV +EPGVP K G Y++ PD+ F ATPPVHG L
Sbjct: 65 AAGTVVETGANVETFKAGDRVCMEPGVPNLSSRATKLGIYNVDPDVSFWATPPVHGVLAP 124
Query: 423 YYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLLTML 599
Y H A F +KLPD+V+ EGA++EP A+G+ A R + G V +V+G GPIG++ L
Sbjct: 125 YAVHPAAFTYKLPDNVSFAEGAMVEPFAIGMQAASRARIVPGDVAVVVGCGPIGIMIAL 183
>UniRef50_P77280 Cluster: Uncharacterized zinc-type alcohol
dehydrogenase-like protein ydjJ; n=16; Bacteria|Rep:
Uncharacterized zinc-type alcohol dehydrogenase-like
protein ydjJ - Escherichia coli (strain K12)
Length = 347
Score = 171 bits (415), Expect = 1e-41
Identities = 82/185 (44%), Positives = 117/185 (63%), Gaps = 4/185 (2%)
Frame = +3
Query: 54 NLTALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEP--- 224
N A+L P ++++ IP EDEVL++++ VGICGSDVH ++ G ++P
Sbjct: 3 NSKAILQVPGTMKIISAEIPVPKEDEVLIKVEYVGICGSDVHGFESGP--FIPPKDPNQE 60
Query: 225 MIMGHEASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPP- 401
+ +GHE +G V +GS+V+ GDRV IEPGVPC +C +C G+Y++CPD+ F AT P
Sbjct: 61 IGLGHECAGTVVAVGSRVRKFKPGDRVNIEPGVPCGHCRYCLEGKYNICPDVDFMATQPN 120
Query: 402 VHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPI 581
G L Y H F +KLPD++ EGAL+EP AVG+HA V G +++LGAG I
Sbjct: 121 YRGALTHYLCHPESFTYKLPDNMDTMEGALVEPAAVGMHAAMLADVKPGKKIIILGAGCI 180
Query: 582 GLLTM 596
GL+T+
Sbjct: 181 GLMTL 185
>UniRef50_Q4PCL3 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 387
Score = 170 bits (414), Expect = 2e-41
Identities = 81/187 (43%), Positives = 115/187 (61%), Gaps = 1/187 (0%)
Frame = +3
Query: 33 ASDMATDNLTALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFV 212
A++ A N++ +L + + + PI +V + + G+C SD HY G+ G FV
Sbjct: 12 ATEPAERNVSFVLQEIEKVSFEERPIVAPKPGQVQVNIRQTGLCASDCHYLHHGRIGDFV 71
Query: 213 LEEPMIMGHEASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCA 392
+ +PM++GHE+SG+V +G V VGDRVA+EPGVPCR C+ C G Y+ C + F A
Sbjct: 72 VRKPMVLGHESSGIVTAVGEGVTTHKVGDRVALEPGVPCRSCQVCLNGMYNQCAHLEFAA 131
Query: 393 TPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIH-ACKRGGVSAGHVVLVLG 569
TPP G L YY + F +PDH+++EE +L+EPL+V ++ A RG V A VLV G
Sbjct: 132 TPPYDGTLCTYYNIQSSFAHHVPDHMSLEEASLMEPLSVAVYSAGMRGQVKAMENVLVFG 191
Query: 570 AGPIGLL 590
AGPIGLL
Sbjct: 192 AGPIGLL 198
>UniRef50_Q4PHJ5 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 382
Score = 170 bits (413), Expect = 2e-41
Identities = 78/185 (42%), Positives = 116/185 (62%), Gaps = 2/185 (1%)
Frame = +3
Query: 51 DNLTALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMI 230
DNL + +L L+++ L+ + G+CGSDVH+W+ G + +E
Sbjct: 18 DNLILMATHKKELELIKSTPAAPGPGMALVHVRATGVCGSDVHFWKHAGLGPWKIESQCA 77
Query: 231 MGHEASGVVAKIGSKVKNLTVGDRVAIEPGVPC--RYCEFCKTGRYHLCPDMIFCATPPV 404
+GHE+ G+V +G V N+ GDRVAIEPGVPC C+FC+TG+Y+LCP + F + PP
Sbjct: 78 LGHESGGIVIAVGEGVDNVVPGDRVAIEPGVPCFKATCDFCRTGKYNLCPTVDFYSVPPK 137
Query: 405 HGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIG 584
G L RY++H A + K+PD+++ EE ALLEPL+V + A + +S G VL+ GAGPIG
Sbjct: 138 DGTLKRYHEHPAGWLHKVPDNMSYEEIALLEPLSVTLQATLQAEISLGTPVLITGAGPIG 197
Query: 585 LLTML 599
++ +L
Sbjct: 198 IVQLL 202
>UniRef50_Q89F70 Cluster: L-idonate 5-dehydrogenase; n=1;
Bradyrhizobium japonicum|Rep: L-idonate 5-dehydrogenase
- Bradyrhizobium japonicum
Length = 349
Score = 169 bits (410), Expect = 6e-41
Identities = 80/190 (42%), Positives = 114/190 (60%), Gaps = 4/190 (2%)
Frame = +3
Query: 42 MATDNLTALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEE 221
M + L A L+ P DLR+++ P+ +++ V +R GICGSD+HY++ + G FV++
Sbjct: 1 MTSTALAATLFGPEDLRMIEHPLDKLASGMVRIRFGAGGICGSDMHYFRHARTGDFVVKS 60
Query: 222 PMIMGHEASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCA--- 392
P+++GHE SG V +I NL VGDRVA+ P C +C C+ GR +LC ++ F
Sbjct: 61 PLVLGHEISGEVVEISGSAANLKVGDRVAVNPSRWCGHCVACREGRPNLCENIYFMGSAS 120
Query: 393 -TPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLG 569
TP + G Y+ C K+PDHV+ + AL EPLAV +HA R G G ++ G
Sbjct: 121 KTPHMQGGFANYFDAIPAQCVKIPDHVSYQAAALAEPLAVCLHAVARAGNIEGKRGIIFG 180
Query: 570 AGPIGLLTML 599
AGPIGLLTML
Sbjct: 181 AGPIGLLTML 190
>UniRef50_Q2UHR2 Cluster: Sorbitol dehydrogenase; n=8;
Ascomycota|Rep: Sorbitol dehydrogenase - Aspergillus
oryzae
Length = 388
Score = 167 bits (407), Expect = 1e-40
Identities = 78/170 (45%), Positives = 104/170 (61%)
Frame = +3
Query: 87 LRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKI 266
L+ + P+ EVLL++ GICGSD+H+W+ G G + + I+GHEA+GVV K
Sbjct: 43 LKAIDAPVYAPKHGEVLLQIKATGICGSDLHFWKTGCIGELIFKGDCIIGHEAAGVVLKC 102
Query: 267 GSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADF 446
G V +L GDRVA+EPGVPC C C GRY+LC D+ F P G + RY H A +
Sbjct: 103 GEGVTHLRPGDRVAVEPGVPCGDCFLCLDGRYNLCEDVQFAGVYPYAGTIQRYKTHPAKW 162
Query: 447 CFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLLTM 596
KLPD++T EGALLEPL+V + G+ G +V GAGPIGL+ +
Sbjct: 163 VHKLPDNLTYAEGALLEPLSVVMRGMSVAGLQLGRGAVVCGAGPIGLIAL 212
>UniRef50_A7F503 Cluster: Putative uncharacterized protein; n=1;
Sclerotinia sclerotiorum 1980|Rep: Putative
uncharacterized protein - Sclerotinia sclerotiorum 1980
Length = 420
Score = 165 bits (400), Expect = 9e-40
Identities = 77/185 (41%), Positives = 114/185 (61%), Gaps = 4/185 (2%)
Frame = +3
Query: 48 TDNLTALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPM 227
TD ++L+ DL++ + EV + + G+CGSD+HY+ + G ++ EPM
Sbjct: 13 TDVKASVLHGAKDLKVETRTLGVPEPTEVQVAVQATGLCGSDLHYYNHYRNGDIIVREPM 72
Query: 228 IMGHEASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIF----CAT 395
+GHE++GVV +GS+VKNL VGD VA+E G+PC+ C+ C +GRY++C +M F A
Sbjct: 73 TLGHESAGVVTAVGSEVKNLKVGDHVALEVGLPCKNCDLCASGRYNICKEMKFRSSAKAF 132
Query: 396 PPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAG 575
P G L H A +C LP +V++E GA+LEPL+V IH +R + G VL+ GAG
Sbjct: 133 PHFQGTLQERINHPAAYCHLLPSNVSLELGAVLEPLSVAIHGSRRAALPKGKTVLIFGAG 192
Query: 576 PIGLL 590
+GLL
Sbjct: 193 AVGLL 197
>UniRef50_A1CNK3 Cluster: Xylitol dehydrogenase XdhB, putative;
n=19; Ascomycota|Rep: Xylitol dehydrogenase XdhB,
putative - Aspergillus clavatus
Length = 386
Score = 162 bits (393), Expect = 7e-39
Identities = 77/157 (49%), Positives = 102/157 (64%)
Frame = +3
Query: 129 EVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGSKVKNLTVGDRVA 308
EV + + GICGSDVH+W G G ++E I+GHE++G V + S V L GDRVA
Sbjct: 44 EVTIEVRSTGICGSDVHFWHAGCIGPMIVEGDHILGHESAGQVIAVASDVTTLKPGDRVA 103
Query: 309 IEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGA 488
IEP + C CE C TGRY+ C + F +TPPV G L RY H A +C K+ D ++ E+GA
Sbjct: 104 IEPNIICNECEPCLTGRYNGCEKVAFLSTPPVDGLLRRYVNHPAIWCHKIGD-MSFEDGA 162
Query: 489 LLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLLTML 599
LLEPL+V + A +R G+ G L+ GAGPIGL+T+L
Sbjct: 163 LLEPLSVSLAAIERSGLRLGDPCLITGAGPIGLITLL 199
>UniRef50_A7II35 Cluster: Alcohol dehydrogenase GroES domain
protein; n=1; Xanthobacter autotrophicus Py2|Rep:
Alcohol dehydrogenase GroES domain protein -
Xanthobacter sp. (strain Py2)
Length = 345
Score = 161 bits (391), Expect = 1e-38
Identities = 77/180 (42%), Positives = 109/180 (60%), Gaps = 4/180 (2%)
Frame = +3
Query: 63 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 242
A+++ DLRL + P PE++ +EVL+ GICGSD+ Y+ KG+ G F L +PM++GHE
Sbjct: 4 AVIHAAKDLRLDECPEPEMAANEVLVSFRAGGICGSDLSYYGKGRVGDFALRQPMVLGHE 63
Query: 243 ASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCAT----PPVHG 410
SG V K+G+ V L +GD VA+ P PC C++C+ GR +LC +M F + P V G
Sbjct: 64 ISGEVIKLGASVSTLALGDHVAVNPSRPCLECDYCRAGRSNLCRNMRFFGSAAIYPHVQG 123
Query: 411 NLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLL 590
+ AD C +P + A+ EPL+V IH +R G AG VL+ GAGPIG+L
Sbjct: 124 AFSETFVCRADQCVSVPRDIPFRRVAMAEPLSVAIHGVRRAGELAGKRVLIAGAGPIGML 183
>UniRef50_A3DI68 Cluster: Alcohol dehydrogenase GroES-like protein;
n=1; Clostridium thermocellum ATCC 27405|Rep: Alcohol
dehydrogenase GroES-like protein - Clostridium
thermocellum (strain ATCC 27405 / DSM 1237)
Length = 347
Score = 160 bits (389), Expect = 2e-38
Identities = 70/172 (40%), Positives = 109/172 (63%), Gaps = 1/172 (0%)
Frame = +3
Query: 87 LRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKI 266
L V+ IP+ E+ +++ VG+CGSD+H++++G+ ++ L+ P+ +GHE G+V+ I
Sbjct: 16 LEWVERDIPQPGRGELQIKLKHVGVCGSDLHFYKEGRLANWELDGPLALGHEPGGIVSAI 75
Query: 267 GSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATP-PVHGNLVRYYKHAAD 443
G V+ +GD+VA+EPGVPC CE C+ G Y+LC + F A P G Y H+A
Sbjct: 76 GEGVEGFEIGDKVALEPGVPCGECEDCRKGHYNLCKHIKFMAIPHEKDGVFAEYCVHSAS 135
Query: 444 FCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLLTML 599
C+KLP++V EG L+EPL+V +HA + G +VLG+G IGL T++
Sbjct: 136 MCYKLPENVDTMEGGLMEPLSVALHATELSNAKIGETAIVLGSGCIGLCTVM 187
>UniRef50_Q5KPJ4 Cluster: Sorbitol dehydrogenase, putative; n=1;
Filobasidiella neoformans|Rep: Sorbitol dehydrogenase,
putative - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 416
Score = 159 bits (387), Expect = 3e-38
Identities = 91/213 (42%), Positives = 118/213 (55%), Gaps = 29/213 (13%)
Frame = +3
Query: 45 ATDNLTALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEP 224
A NL +L+ P + +PEI DEVL+ + GICGSDVH++ G+ G L E
Sbjct: 20 AKSNLGFMLHSPLKTSFEEQSVPEIGPDEVLVEIKKTGICGSDVHFYNTGKMGLAALTES 79
Query: 225 MIMGHEASGVVAKIGSK-------------------------VKN--LTVGDRVAIEPGV 323
M +GHE+SG+V ++GS V N L VGD+VA+EPGV
Sbjct: 80 MCLGHESSGIVVQLGSNIVQQAARSNVMATARGEAEESNKGTVSNRPLQVGDKVALEPGV 139
Query: 324 PCRYCEFCKTGRYHLCPDMIFCATPP-VHGNLVRYYKHAADFCFKLPDHVTMEEGALLEP 500
CR C CK G+Y +C MIF A PP G L RYY AD + LPD+V + GA++EP
Sbjct: 140 TCRMCVDCKGGKYQICEHMIFAAYPPSTGGTLQRYYALPADLVYPLPDNVDLSFGAMMEP 199
Query: 501 LAVGIHACKR-GGVSAGHVVLVLGAGPIGLLTM 596
L+V HA GG+ G VL+ GAGP+GLL M
Sbjct: 200 LSVATHAVANIGGMRTGWNVLITGAGPVGLLAM 232
>UniRef50_Q7S9B3 Cluster: Putative uncharacterized protein
NCU07022.1; n=5; Pezizomycotina|Rep: Putative
uncharacterized protein NCU07022.1 - Neurospora crassa
Length = 437
Score = 159 bits (385), Expect = 6e-38
Identities = 81/181 (44%), Positives = 108/181 (59%), Gaps = 4/181 (2%)
Frame = +3
Query: 63 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 242
++L+ P DLRL + I E E+ + + GICGSDV Y++K G P+ +GHE
Sbjct: 26 SVLHGPRDLRLERRTIEEPELGELQVAVKTTGICGSDVSYYKKFANGDLCACMPLSLGHE 85
Query: 243 ASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCAT----PPVHG 410
+SGVV IG +V ++GDRVA+E GV C C C+ GRY+LC M F ++ P G
Sbjct: 86 SSGVVVAIGPQVSGFSLGDRVALEVGVACGQCTICRKGRYNLCKKMRFRSSAKSVPHYQG 145
Query: 411 NLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLL 590
L H A +C LPDH++ + ALLEPL+VGIHA R + G LVLGAG +GLL
Sbjct: 146 TLQERINHPAIWCHILPDHISFDAAALLEPLSVGIHAVNRASPAPGSTALVLGAGTVGLL 205
Query: 591 T 593
T
Sbjct: 206 T 206
>UniRef50_A2QU04 Cluster: Catalytic activity: L-iditol + NAD(+) =
L-sorbose + NADH; n=8; Eurotiomycetidae|Rep: Catalytic
activity: L-iditol + NAD(+) = L-sorbose + NADH -
Aspergillus niger
Length = 405
Score = 159 bits (385), Expect = 6e-38
Identities = 85/199 (42%), Positives = 116/199 (58%), Gaps = 17/199 (8%)
Frame = +3
Query: 45 ATDNLTAL-LYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEE 221
+T+ AL L+ DLRL P+ + EV + + G+CGSD+HY+ G+ G FV+ E
Sbjct: 5 STETTQALVLHGAKDLRLESRPLSPPTGSEVQVAIRATGLCGSDLHYYTHGRNGDFVVRE 64
Query: 222 PMIMGHEASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCAT-- 395
PM +GHE+SG++ IG +V VGDRVA+E G+PCR C C+ GRY++CP M F ++
Sbjct: 65 PMCLGHESSGIITAIGPEVTTHAVGDRVALEVGLPCRQCALCQQGRYNICPQMKFRSSAK 124
Query: 396 --PPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRG----------GV 539
P + G L+ H A C KLP HV+ GAL+EPLAV +HA +R
Sbjct: 125 LFPHLDGTLMERTNHPASLCHKLPSHVSYAGGALVEPLAVCLHAIRRSRPPTAEDVSLAQ 184
Query: 540 SAGH--VVLVLGAGPIGLL 590
S G L+ GAG IGLL
Sbjct: 185 SLGEPTAALIFGAGAIGLL 203
>UniRef50_Q0UEG3 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 320
Score = 155 bits (377), Expect = 6e-37
Identities = 70/143 (48%), Positives = 94/143 (65%)
Frame = +3
Query: 168 SDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFC 347
SD+H+W++G+ G V+E I+GHEA+GVV + G V +L GDRVA+EPGVPC C C
Sbjct: 28 SDIHFWKRGRIGSLVVEGDCILGHEAAGVVLECGEGVISLKPGDRVAVEPGVPCETCFLC 87
Query: 348 KTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACK 527
GRY+LC D+ F P G + RY H A +C LP +V+ EGALLEPL+V +H K
Sbjct: 88 MDGRYNLCEDVKFSGVYPDAGTIQRYKTHPARWCHILPSNVSYSEGALLEPLSVVMHGIK 147
Query: 528 RGGVSAGHVVLVLGAGPIGLLTM 596
G+S G ++ GAGPIGL+ +
Sbjct: 148 SAGLSLGRGAVICGAGPIGLIAL 170
>UniRef50_A3GIE9 Cluster: Sorbitol dehydrogenase; n=2;
Saccharomycetaceae|Rep: Sorbitol dehydrogenase - Pichia
stipitis (Yeast)
Length = 381
Score = 154 bits (374), Expect = 1e-36
Identities = 78/192 (40%), Positives = 111/192 (57%), Gaps = 9/192 (4%)
Frame = +3
Query: 51 DNLTALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMI 230
+N L L + PIP +EVL+ + C GICGSD+H W+ G G+ L+ +I
Sbjct: 13 ENTCLKLTSDRQLVIDSEPIPICGRNEVLVHIKCTGICGSDIHVWKAGGIGNLQLKSDLI 72
Query: 231 MGHEASGVVAKIGSKV-KNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCA----- 392
+GHE SG + IGS+V ++ +G++VAIEP +PC C C G +LC ++ F
Sbjct: 73 LGHECSGEIIHIGSEVTEDFEIGNKVAIEPQLPCGICFLCTNGNMNLCLNVDFMGMPGMP 132
Query: 393 --TPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHAC-KRGGVSAGHVVLV 563
P +HG++ RY F +KLPD+VT EEGAL+E L+VG H K GG+ G +
Sbjct: 133 GRLPSIHGSIQRYKTLDPRFVYKLPDNVTYEEGALVEVLSVGYHGIQKAGGLELGKPCAI 192
Query: 564 LGAGPIGLLTML 599
G GPIGL T++
Sbjct: 193 AGCGPIGLATLI 204
>UniRef50_Q3ACJ3 Cluster: Sorbitol dehydrogenase; n=1;
Carboxydothermus hydrogenoformans Z-2901|Rep: Sorbitol
dehydrogenase - Carboxydothermus hydrogenoformans
(strain Z-2901 / DSM 6008)
Length = 345
Score = 153 bits (371), Expect = 3e-36
Identities = 68/179 (37%), Positives = 104/179 (58%)
Frame = +3
Query: 63 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 242
A+L +P + + P+PE+ + +VL++++ VGICGSD+H + G G VL++P+++GHE
Sbjct: 4 AVLMEPKKIIFKEVPVPELEKGKVLIKVEAVGICGSDMHLYLDGHIGATVLDKPLVLGHE 63
Query: 243 ASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVR 422
G V ++G V +G RV ++PG C CE C+TG Y+LC F PPV G +
Sbjct: 64 IVGTVIEVGEGVNRELLGQRVIVDPGENCGQCEHCRTGAYNLCSFSKFKGIPPVDGGMAE 123
Query: 423 YYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLLTML 599
Y A LP+++ LLEP +VG+ A AG + VLG GP+G+LT +
Sbjct: 124 YITALATHVIPLPENLDSPTATLLEPFSVGLQAVDVADFRAGAKIAVLGGGPVGVLTAI 182
>UniRef50_A1DK00 Cluster: Alcohol dehydrogenase; n=7;
Pezizomycotina|Rep: Alcohol dehydrogenase - Neosartorya
fischeri (strain ATCC 1020 / DSM 3700 / NRRL
181)(Aspergillus fischerianus (strain ATCC 1020 / DSM
3700 / NRRL 181))
Length = 385
Score = 152 bits (368), Expect = 7e-36
Identities = 77/181 (42%), Positives = 111/181 (61%), Gaps = 7/181 (3%)
Frame = +3
Query: 69 LYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEAS 248
L+ P LRL P+ I +V +R+ +CGSDVHY++ + G ++EP+ GHEA+
Sbjct: 13 LHGPQQLRLEARPMTSIGPSDVRIRVRSTTLCGSDVHYFKFHRNGSIEVKEPLCGGHEAA 72
Query: 249 GVVAKIGS---KVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCAT----PPVH 407
G V ++G K + + VGD VAIE GV C C+ C++GRY++C M F ++ P
Sbjct: 73 GEVVEVGPTVLKTQAIRVGDIVAIESGVACLECDKCRSGRYNICAKMRFRSSGASFPHFQ 132
Query: 408 GNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGL 587
G L Y H A++C KLPD ++ ++GALLEPL+V IH+ R GV G +V GAG +GL
Sbjct: 133 GTLQEYVDHPAEWCHKLPDALSYDDGALLEPLSVCIHSVNRAGVDQGARCVVFGAGAVGL 192
Query: 588 L 590
L
Sbjct: 193 L 193
>UniRef50_Q5KAN3 Cluster: Xylitol dehydrogenase, putative; n=1;
Filobasidiella neoformans|Rep: Xylitol dehydrogenase,
putative - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 375
Score = 151 bits (367), Expect = 9e-36
Identities = 74/169 (43%), Positives = 108/169 (63%), Gaps = 7/169 (4%)
Frame = +3
Query: 108 IPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGSKVK-- 281
IPE DEV +++ G+CGSD+HY+ G G F + EP+++GHE+ GV+ +GS V
Sbjct: 11 IPEPKADEVQIKVAMTGMCGSDLHYYLHGANGTFKIREPLVLGHESCGVITAVGSNVNSG 70
Query: 282 -NLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCAT----PPVHGNLVRYYKHAADF 446
NL VGDRVA+E GV C+ C+ C+ GRY+LC +M F ++ P + G L A+
Sbjct: 71 FNLKVGDRVAMEVGVYCKTCKMCRRGRYNLCANMRFASSAKTYPHLDGTLREVMTWPAEL 130
Query: 447 CFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLLT 593
+KLP ++ + AL EPL+V +HA +R +S G +LV+GAG +GLLT
Sbjct: 131 VYKLPPNLELPLAALAEPLSVVLHAYRRAHLSPGSRILVIGAGAVGLLT 179
>UniRef50_UPI0000DD8301 Cluster: PREDICTED: similar to Sorbitol
dehydrogenase (L-iditol 2-dehydrogenase); n=1; Homo
sapiens|Rep: PREDICTED: similar to Sorbitol
dehydrogenase (L-iditol 2-dehydrogenase) - Homo sapiens
Length = 323
Score = 149 bits (361), Expect = 5e-35
Identities = 68/106 (64%), Positives = 82/106 (77%), Gaps = 1/106 (0%)
Frame = +3
Query: 261 KIGSKV-KNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHA 437
++GS+ K L GDRVAIE G P EFCK GRY+L P + FCATPP GNL ++YKH
Sbjct: 61 RLGSREQKKLKPGDRVAIESGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLCQFYKHN 120
Query: 438 ADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAG 575
A FC+KLPD+VT EEGAL++PL+VGIHAC+RGGV+ GH VLV GAG
Sbjct: 121 AAFCYKLPDNVTFEEGALIDPLSVGIHACRRGGVTLGHKVLVCGAG 166
>UniRef50_Q5LQR4 Cluster: L-idonate 5-dehydrogenase; n=13;
Alphaproteobacteria|Rep: L-idonate 5-dehydrogenase -
Silicibacter pomeroyi
Length = 349
Score = 144 bits (349), Expect = 1e-33
Identities = 77/178 (43%), Positives = 99/178 (55%), Gaps = 4/178 (2%)
Frame = +3
Query: 69 LYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEAS 248
++ D+R+ P+PE +V++ M GICGSD+HY+ G G + EPMI+GHE +
Sbjct: 8 IHAARDIRVETDPLPEPGPAQVIVAMAAAGICGSDLHYYHDGGFGPIRVREPMILGHEGA 67
Query: 249 GVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCAT----PPVHGNL 416
GVVA +G V L VGDRVA+ P PC C +C G C +M F + P G
Sbjct: 68 GVVAALGPGVTGLAVGDRVAVNPSRPCGTCSYCVEGLTTHCLNMRFYGSAMRFPHEQGLF 127
Query: 417 VRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLL 590
A C KL DHVT+ EGA EPLAV +HA G G VLV G+GPIG+L
Sbjct: 128 RDKLLTDAAQCHKLSDHVTISEGACAEPLAVCLHARHMAGEVRGKRVLVTGSGPIGVL 185
>UniRef50_Q5KJG0 Cluster: Xylitol dehydrogenase, putative; n=1;
Filobasidiella neoformans|Rep: Xylitol dehydrogenase,
putative - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 469
Score = 144 bits (349), Expect = 1e-33
Identities = 67/145 (46%), Positives = 91/145 (62%)
Frame = +3
Query: 159 ICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYC 338
ICGSD+H + G G + EP++MGHE+SG V +G VK VGDRVAIEPG+PCR C
Sbjct: 81 ICGSDLHNYLAGGVGGRPVTEPIVMGHESSGEVIAVGDLVKTHKVGDRVAIEPGLPCRRC 140
Query: 339 EFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIH 518
CK G+ ++C +M +C P G+L RY+ AD +PDH++ EE ++PLAVGI
Sbjct: 141 INCKEGKVNICLNMHYCGAPGSVGSLSRYFALPADMAPHIPDHLSWEEAGCIQPLAVGIQ 200
Query: 519 ACKRGGVSAGHVVLVLGAGPIGLLT 593
KR + V + G GPIGL++
Sbjct: 201 VGKRVDLRPHKTVAIFGCGPIGLIS 225
>UniRef50_Q01VI1 Cluster: Alcohol dehydrogenase GroES domain
protein; n=1; Solibacter usitatus Ellin6076|Rep: Alcohol
dehydrogenase GroES domain protein - Solibacter usitatus
(strain Ellin6076)
Length = 343
Score = 144 bits (348), Expect = 2e-33
Identities = 67/180 (37%), Positives = 102/180 (56%)
Frame = +3
Query: 57 LTALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMG 236
L A L R + PI + EV +R++ VGICGSD+H + +G G E PM++G
Sbjct: 2 LVAELIAQRQFRFTEIPIEDPGPGEVQVRVNAVGICGSDLHSYAEGAIGDTPCEYPMVLG 61
Query: 237 HEASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNL 416
HE +G V K G+ V + GDR A+EP + C +CEFC++GR+++C ++ F + P G
Sbjct: 62 HEPAGTVVKTGTGVGGWSRGDRAALEPALYCYHCEFCRSGRHNICANIRFLSNPGTPGFF 121
Query: 417 VRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLLTM 596
+ +P +++E ++EPLAV +H+ K + V V GAGPIGLLT+
Sbjct: 122 REFVNLPVSNLLAIPPELSLELATIVEPLAVALHSLKFAAIQPRETVAVFGAGPIGLLTI 181
>UniRef50_Q39JN7 Cluster: Zinc-containing alcohol dehydrogenase
superfamily; n=17; Proteobacteria|Rep: Zinc-containing
alcohol dehydrogenase superfamily - Burkholderia sp.
(strain 383) (Burkholderia cepacia (strain ATCC 17760/
NCIB 9086 / R18194))
Length = 352
Score = 143 bits (347), Expect = 2e-33
Identities = 74/184 (40%), Positives = 104/184 (56%), Gaps = 4/184 (2%)
Frame = +3
Query: 57 LTALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMG 236
+ +++ PNDLR+ + EI +V + + GICGSD+HY++ G G L++PM++G
Sbjct: 6 MCVVIHGPNDLRVEEQDAGEIGPGQVRVDVAMGGICGSDLHYFRHGGFGAIRLQQPMVLG 65
Query: 237 HEASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCAT----PPV 404
HE +G VA++ V ++ VGDRVA+ P PC C +C G + C DM F + P V
Sbjct: 66 HEVAGTVAEVAPDVTSVKVGDRVAVNPSRPCGACRYCLEGLPNQCLDMRFYGSAMRMPHV 125
Query: 405 HGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIG 584
G A C K+ DHV + AL EP AVG+HA R G G VLV G GPIG
Sbjct: 126 QGAFRNALVCDAVQCVKVADHVPLSLAALAEPFAVGLHAVSRAGPLIGKRVLVSGCGPIG 185
Query: 585 LLTM 596
+L +
Sbjct: 186 VLAV 189
>UniRef50_A1WNS6 Cluster: Alcohol dehydrogenase GroES domain
protein; n=1; Verminephrobacter eiseniae EF01-2|Rep:
Alcohol dehydrogenase GroES domain protein -
Verminephrobacter eiseniae (strain EF01-2)
Length = 345
Score = 138 bits (335), Expect = 7e-32
Identities = 68/181 (37%), Positives = 104/181 (57%), Gaps = 4/181 (2%)
Frame = +3
Query: 69 LYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEAS 248
++ DLR+ P ++ +V + + VGICGSD+HY+Q G+ G FV+ P+ GHEAS
Sbjct: 6 IHGARDLRIADRPAEPLAAHQVRVGVKAVGICGSDLHYYQHGRVGDFVIRAPLTPGHEAS 65
Query: 249 GVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCAT----PPVHGNL 416
G V ++G++V+ L G RVA+ P C C FC+ G + C ++ F + P + G +
Sbjct: 66 GQVLELGAQVQGLQPGQRVALNPSRSCGVCRFCRAGAANHCENVHFFGSASKWPHMQGAM 125
Query: 417 VRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLLTM 596
A C +PD ++ E A EPLAV +HA ++ G G V+V+GAGPIG L +
Sbjct: 126 REQVVLDAAQCIAVPDALSYEVAAFGEPLAVALHAVRQAGSLLGKSVMVVGAGPIGALVL 185
Query: 597 L 599
+
Sbjct: 186 M 186
>UniRef50_A0GHL5 Cluster: Alcohol dehydrogenase GroES-like; n=1;
Burkholderia phytofirmans PsJN|Rep: Alcohol
dehydrogenase GroES-like - Burkholderia phytofirmans
PsJN
Length = 348
Score = 135 bits (326), Expect = 9e-31
Identities = 70/187 (37%), Positives = 104/187 (55%), Gaps = 7/187 (3%)
Frame = +3
Query: 57 LTALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMG 236
L A+L++P +R+ + PE EV +R+ GICGSD+ Y+ KG+ G F + EP ++G
Sbjct: 2 LAAVLHEPKLIRIDEVDPPEPGPGEVRVRVRAGGICGSDLSYYFKGKSGDFAVREPFVLG 61
Query: 237 HEASGVVAKIGSKV---KNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCAT---- 395
HE +G + +G V + L G RVA+ PG+ C C FC G + C +M F +
Sbjct: 62 HEVAGEIDSLGEGVTAERRLAPGQRVAVNPGLACGTCRFCVGGMPNHCLNMRFMGSASTF 121
Query: 396 PPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAG 575
P G +Y AA C +PD V + ++ EPLAV +HA K+ G G VL++G G
Sbjct: 122 PHTQGMFRQYIVVAARQCVPVPDGVDFAQASMAEPLAVALHAVKQAGSLVGASVLLVGCG 181
Query: 576 PIGLLTM 596
PIG + +
Sbjct: 182 PIGCILL 188
>UniRef50_A5D1M5 Cluster: Threonine dehydrogenase and related
Zn-dependent dehydrogenases; n=1; Pelotomaculum
thermopropionicum SI|Rep: Threonine dehydrogenase and
related Zn-dependent dehydrogenases - Pelotomaculum
thermopropionicum SI
Length = 329
Score = 133 bits (322), Expect = 3e-30
Identities = 71/180 (39%), Positives = 104/180 (57%)
Frame = +3
Query: 57 LTALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMG 236
L Y D+R+ P P DEVL+++ GICGSD+H ++KG F+ P+ MG
Sbjct: 2 LAVRYYGIGDIRVENIPKPAPGHDEVLVKVAYAGICGSDLHIFRKGM---FISSAPVTMG 58
Query: 237 HEASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNL 416
HE SGVV ++G+ V L GD+V +P VPC C++C+ +Y+LCP + F G
Sbjct: 59 HEFSGVVEEVGAGVTGLRPGDQVVGDPRVPCGRCQWCRREQYNLCPGLGFIGEVR-PGCF 117
Query: 417 VRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLLTM 596
+ K+P + ++E L+EPLAV +H K+G +S + V +LGAGPIGLLT+
Sbjct: 118 AEHIAINYKKLLKVP-ALDLKEAVLVEPLAVAVHIAKKGKLSPENTVGILGAGPIGLLTL 176
>UniRef50_A6X6E2 Cluster: Alcohol dehydrogenase GroES domain
protein; n=1; Ochrobactrum anthropi ATCC 49188|Rep:
Alcohol dehydrogenase GroES domain protein -
Ochrobactrum anthropi (strain ATCC 49188 / DSM 6882 /
NCTC 12168)
Length = 358
Score = 132 bits (320), Expect = 5e-30
Identities = 74/182 (40%), Positives = 96/182 (52%), Gaps = 8/182 (4%)
Frame = +3
Query: 69 LYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEAS 248
L+ +DLR+ P+ EVL+ ++ GICGSD+HYW +G G + EP+I+GHEAS
Sbjct: 12 LHAQDDLRIESRPVGTPGPGEVLIAVEAGGICGSDLHYWLEGGIGTIRVREPIILGHEAS 71
Query: 249 GVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCAT----PPVHGNL 416
G + +G V L G VA+ P PC C FC+ G C M F + P G
Sbjct: 72 GRIKALGEGVTGLVPGQLVAMNPSQPCGICSFCQQGLTRHCSAMRFKGSAMYLPHQQGMF 131
Query: 417 VRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRG----GVSAGHVVLVLGAGPIG 584
AAD CF +P+ + A EPLAV +HA RG G G VV+V GAGPIG
Sbjct: 132 RDRIVIAADQCFPVPNGIDPGAAACSEPLAVCLHAANRGEAIAGSLVGKVVMVTGAGPIG 191
Query: 585 LL 590
L
Sbjct: 192 AL 193
>UniRef50_A0QWX1 Cluster: Oxidoreductase, zinc-binding dehydrogenase
family protein; n=3; Bacteria|Rep: Oxidoreductase,
zinc-binding dehydrogenase family protein -
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Length = 363
Score = 132 bits (319), Expect = 6e-30
Identities = 65/178 (36%), Positives = 101/178 (56%)
Frame = +3
Query: 63 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 242
A++Y P D+R+ Q P+P EVLL++ G+CGSD+ + G +V+ P+I GHE
Sbjct: 24 AVMYAPGDIRVEQAPVPRPGPGEVLLKVAACGVCGSDIPRMLRN--GGYVM--PIICGHE 79
Query: 243 ASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVR 422
SG V ++G V+ +G+ V++ P +PCR C+FC G + LC + + + G +
Sbjct: 80 FSGWVVELGDGVEGFDIGELVSVPPLIPCRRCDFCAKGEFGLCENYDYFGSRS-DGAYAQ 138
Query: 423 YYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLLTM 596
Y KLP + A+L+P A+ +H + G+ AGH VLV+GAGPIGL +
Sbjct: 139 YVVSPVGNLLKLPAGIDPRAAAMLDPAAIALHGLWKTGLRAGHRVLVIGAGPIGLFAI 196
>UniRef50_A6BDE4 Cluster: Putative uncharacterized protein; n=2;
Clostridiales|Rep: Putative uncharacterized protein -
Dorea longicatena DSM 13814
Length = 347
Score = 130 bits (313), Expect = 3e-29
Identities = 67/178 (37%), Positives = 101/178 (56%)
Frame = +3
Query: 57 LTALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMG 236
L ++ KP ++ + P+PE+ +D+VL+++ +GICGSD+H + G+ H P+ G
Sbjct: 8 LQQVMTKPGEIIFREVPVPEVKDDQVLVKIMNIGICGSDIHVYH-GK--HPFTSYPVTQG 64
Query: 237 HEASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNL 416
HE SG V K+G V G +V IEP V C C C+ G+Y+LC ++ G
Sbjct: 65 HEVSGEVVKLGKDVTVFHEGQKVTIEPQVYCGECYPCRHGKYNLCEELKVMGFQTT-GTA 123
Query: 417 VRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLL 590
Y+ A +P+ ++ EEGA++EPLAV +H K+ G G + VLGAGPIG L
Sbjct: 124 SEYFAVDASKVTPIPEEMSYEEGAMIEPLAVAVHGVKQVGDVKGMNIAVLGAGPIGNL 181
>UniRef50_Q930C9 Cluster: IdnD L-idonate 5-dehydrogenase; n=4;
Alphaproteobacteria|Rep: IdnD L-idonate 5-dehydrogenase
- Rhizobium meliloti (Sinorhizobium meliloti)
Length = 343
Score = 129 bits (312), Expect = 4e-29
Identities = 70/182 (38%), Positives = 101/182 (55%), Gaps = 4/182 (2%)
Frame = +3
Query: 66 LLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEA 245
+++ DLR+ + + + EV +R+ GICGSD+HY+ G G L+EPMI+GHE
Sbjct: 5 VIHTAKDLRVEECAVEKPGPGEVEIRLAAGGICGSDLHYYNHGGFGTVRLKEPMILGHEV 64
Query: 246 SGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCAT----PPVHGN 413
SG VA +G V +L +GD VA+ P PC C++C G + C M F + P + G
Sbjct: 65 SGHVAALGEGVSDLAIGDLVAVSPSRPCGACDYCLKGLPNHCFHMRFYGSAMPFPHIQGA 124
Query: 414 LVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLLT 593
A C K + ++ E A+ EPL+V +HA +R G G VLV G GPIG L+
Sbjct: 125 FRERLVAKASQCVK-AEGLSAGEAAMAEPLSVTLHATRRAGEMLGKRVLVTGCGPIGTLS 183
Query: 594 ML 599
+L
Sbjct: 184 IL 185
>UniRef50_Q81V29 Cluster: Alcohol dehydrogenase, zinc-containing;
n=19; Bacteria|Rep: Alcohol dehydrogenase,
zinc-containing - Bacillus anthracis
Length = 350
Score = 129 bits (312), Expect = 4e-29
Identities = 67/184 (36%), Positives = 99/184 (53%), Gaps = 7/184 (3%)
Frame = +3
Query: 66 LLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQC-----GHFV--LEEP 224
L + D+R+ + P P + V +++ GICG+D+H + G H + ++ P
Sbjct: 5 LWHNQRDVRVEEVPEPTVKPGAVKIKVKWCGICGTDLHEYLAGPIFIPTEEHPLTHVKAP 64
Query: 225 MIMGHEASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPV 404
+I+GHE SG V +IG V + VGDRV +EP C CE CK G Y++C ++F
Sbjct: 65 VILGHEFSGEVVEIGEGVTSHKVGDRVVVEPIYSCGKCEACKHGHYNVCEQLVFHGLGGE 124
Query: 405 HGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIG 584
G Y D +PD +T E+GAL+EP AV +HA ++ + G V V G GPIG
Sbjct: 125 GGGFSEYTVVPEDMVHHIPDEMTYEQGALVEPAAVAVHAVRQSKLKEGEAVAVFGCGPIG 184
Query: 585 LLTM 596
LL +
Sbjct: 185 LLVI 188
>UniRef50_A0NKD6 Cluster: Zc-binding dehydrogenase; n=3; Oenococcus
oeni|Rep: Zc-binding dehydrogenase - Oenococcus oeni
ATCC BAA-1163
Length = 385
Score = 129 bits (312), Expect = 4e-29
Identities = 75/195 (38%), Positives = 106/195 (54%), Gaps = 13/195 (6%)
Frame = +3
Query: 54 NLTALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQ----CGHFVLEE 221
++ +LY P D+RL + IP+ +D+V + + GICGSD+H + G H + E
Sbjct: 27 SIAQVLYGPKDMRLEKVDIPDPGKDQVQISVYFNGICGSDIHEYLDGMDLATVEHPITHE 86
Query: 222 --PMIMGHEASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMI---- 383
P+I GHE +G V K G+ VK L VGD V +EP + C YC C++G Y+LC + I
Sbjct: 87 KAPLISGHEFAGKVKKTGALVKGLKVGDHVTVEPIIACGYCAACRSGNYNLCENSIGEDN 146
Query: 384 ---FCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHV 554
F +G L + + + KLPD + + GAL EP AV A + AG
Sbjct: 147 AAGFLGF-SANGGLSQLCNVSYIYAHKLPDDLPLSLGALCEPTAVAAQAIFNSKIHAGDD 205
Query: 555 VLVLGAGPIGLLTML 599
VL+ GAGPIGLLT +
Sbjct: 206 VLISGAGPIGLLTAI 220
>UniRef50_Q5KJK1 Cluster: Zinc-binding dehydrogenase, putative;
n=16; Dikarya|Rep: Zinc-binding dehydrogenase, putative
- Cryptococcus neoformans (Filobasidiella neoformans)
Length = 349
Score = 129 bits (312), Expect = 4e-29
Identities = 66/184 (35%), Positives = 102/184 (55%), Gaps = 1/184 (0%)
Frame = +3
Query: 42 MATDNLTALLY-KPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLE 218
M + ALLY +P + ++ + P+PEI +E+LL++D G+CG+D H + G F+ +
Sbjct: 1 MVAKEMNALLYSEPRNFKITKVPVPEIGPEEILLKVDICGVCGTDQHIHE----GEFIAK 56
Query: 219 EPMIMGHEASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATP 398
P++ GHEA G + +G KVK +GDR+A + G C YC +C+ G C + A
Sbjct: 57 FPLVPGHEAVGRIVSMGDKVKGFDIGDRIAADVGETCGYCHYCRKGTDLFCENFA-PAGV 115
Query: 399 PVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGP 578
G Y K+ C+K+ ++T EE LLEP + IH + G VL++GAGP
Sbjct: 116 ARDGGFADYIKYHFAKCYKI-KNLTDEEATLLEPASCAIHGMDVLKMPFGARVLLIGAGP 174
Query: 579 IGLL 590
GL+
Sbjct: 175 TGLI 178
>UniRef50_A5FZ32 Cluster: Alcohol dehydrogenase GroES domain
protein; n=1; Acidiphilium cryptum JF-5|Rep: Alcohol
dehydrogenase GroES domain protein - Acidiphilium
cryptum (strain JF-5)
Length = 339
Score = 129 bits (311), Expect = 6e-29
Identities = 62/169 (36%), Positives = 91/169 (53%)
Frame = +3
Query: 84 DLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAK 263
D+ + P P D + + + VG+CGSD+HY+ +G G V+ EP + GHE + V +
Sbjct: 11 DITIGDAPEPVPGNDRIAVEVAGVGVCGSDLHYYLEGSIGSQVIVEPFVPGHEFAARVIE 70
Query: 264 IGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAAD 443
++ L G+ +A++P +PC +CE+C G +LCPD +F PP G +
Sbjct: 71 ARPEL-GLAKGELIAVDPAMPCGHCEWCHRGEINLCPDTVFNGAPPYPGAMAERMAIEPR 129
Query: 444 FCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLL 590
K+P H T+EE +LEPL V IHA V V+G GPIGLL
Sbjct: 130 QVVKVPQHFTIEETMMLEPLGVAIHAIDLARPRLLESVAVIGCGPIGLL 178
>UniRef50_A3PQM0 Cluster: Alcohol dehydrogenase GroES domain
protein; n=1; Rhodobacter sphaeroides ATCC 17029|Rep:
Alcohol dehydrogenase GroES domain protein - Rhodobacter
sphaeroides (strain ATCC 17029 / ATH 2.4.9)
Length = 345
Score = 127 bits (307), Expect = 2e-28
Identities = 70/173 (40%), Positives = 92/173 (53%), Gaps = 4/173 (2%)
Frame = +3
Query: 84 DLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAK 263
DL + P + EV L + GICGSD+HY+Q G+ + +L EPMI+GHE SG + +
Sbjct: 11 DLSIEPWAEPALQAGEVRLDLAWGGICGSDLHYFQHGRVANSILREPMILGHEFSGRIRE 70
Query: 264 IGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCAT----PPVHGNLVRYYK 431
+G V+ L G VA+ P PC C+ C G HLC M F + P HG
Sbjct: 71 VGPGVQWLKPGMAVAVNPSRPCGSCDQCSAGLTHLCRSMRFMGSAAHFPHTHGGFAERPV 130
Query: 432 HAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLL 590
A C LP+ V + AL EP AV +HA + ++AG VLV GAG IG L
Sbjct: 131 VLASQCVALPETVDLALAALSEPYAVALHAVELAQIAAGASVLVTGAGTIGSL 183
>UniRef50_Q8EL78 Cluster: Alcohol dehydrogenase; n=1; Oceanobacillus
iheyensis|Rep: Alcohol dehydrogenase - Oceanobacillus
iheyensis
Length = 351
Score = 126 bits (304), Expect = 4e-28
Identities = 74/187 (39%), Positives = 97/187 (51%), Gaps = 8/187 (4%)
Frame = +3
Query: 63 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKG----QCG--HFVLEE- 221
A+ Y +D+R+ P I +V +++ GICGSD+H + Q G H V E
Sbjct: 4 AVWYGKHDIRVENKEEPIIKPGKVKIKVAWTGICGSDLHAYHGAEGVVQVGEPHPVTGEM 63
Query: 222 -PMIMGHEASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATP 398
P+ +GHE SGV+ +IG V L+VGDRVAIEP + C CE C G Y+LC F
Sbjct: 64 APLTLGHEFSGVIHEIGEGVSGLSVGDRVAIEPAIKCGKCENCVRGNYNLCEHNGFVGLQ 123
Query: 399 PVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGP 578
G Y KLPD+++ EE +EP AV HA K + AG V V G GP
Sbjct: 124 S-DGAFAEYAIVDPHMVHKLPDNISFEEATAIEPTAVSFHALKLSNMKAGDTVAVFGVGP 182
Query: 579 IGLLTML 599
IGL +L
Sbjct: 183 IGLTAIL 189
>UniRef50_A3DCE7 Cluster: Alcohol dehydrogenase GroES-like protein;
n=1; Clostridium thermocellum ATCC 27405|Rep: Alcohol
dehydrogenase GroES-like protein - Clostridium
thermocellum (strain ATCC 27405 / DSM 1237)
Length = 344
Score = 126 bits (303), Expect = 5e-28
Identities = 64/178 (35%), Positives = 102/178 (57%)
Frame = +3
Query: 57 LTALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMG 236
L +++ P + + PE+ +VL+++ +GICGSD+H G+ H + P+ G
Sbjct: 2 LQSVMVSPGKIEFHEVEKPELKPGQVLIKIMRIGICGSDIHV-NHGK--HPFTKYPVTQG 58
Query: 237 HEASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNL 416
HE SG + ++ V++L VG +V IEP V C C C+TG+Y+LC ++ V G
Sbjct: 59 HEVSGKIVEVAEDVEHLKVGQKVTIEPQVVCGKCHPCRTGKYNLCEELKVMGFQTV-GAG 117
Query: 417 VRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLL 590
Y+ A +PDH++ +E A++EPLAV +HA R G ++V+GAGPIG+L
Sbjct: 118 SEYFAVDAKNVTTVPDHLSYDEAAMIEPLAVTVHAANRVGDVKDKDIVVIGAGPIGIL 175
>UniRef50_A1SCW8 Cluster: Alcohol dehydrogenase, zinc-binding domain
protein; n=1; Nocardioides sp. JS614|Rep: Alcohol
dehydrogenase, zinc-binding domain protein -
Nocardioides sp. (strain BAA-499 / JS614)
Length = 338
Score = 126 bits (303), Expect = 5e-28
Identities = 71/182 (39%), Positives = 96/182 (52%), Gaps = 3/182 (1%)
Frame = +3
Query: 57 LTALLYKPNDLRLVQT---PIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPM 227
+ A L+ DLR+ Q P P + V + VG+CGSD+H++ G G L+ P+
Sbjct: 3 VAARLHSVGDLRVEQVAEPPAPTVGWSTVAVTS--VGLCGSDLHWFTDGGTGEVTLDRPV 60
Query: 228 IMGHEASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVH 407
+ GHE +G + G RVAI+P +PC CE C+ G +LCPD+ F +
Sbjct: 61 VPGHELAG------RALDGPYAGRRVAIDPAIPCGVCEQCRAGHGNLCPDVRFAGHAGLD 114
Query: 408 GNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGL 587
G L F LPD ++ + GALLEPL V IHA V GH VLV+G GPIG+
Sbjct: 115 GGLQERLVWPDHLLFPLPDDLSDDAGALLEPLGVAIHAVGVAHVRPGHDVLVVGGGPIGV 174
Query: 588 LT 593
LT
Sbjct: 175 LT 176
>UniRef50_Q38ZV8 Cluster: Zinc-containing alcohol dehydrogenase
superfamily; n=17; Proteobacteria|Rep: Zinc-containing
alcohol dehydrogenase superfamily - Burkholderia sp.
(strain 383) (Burkholderia cepacia (strain ATCC 17760/
NCIB 9086 / R18194))
Length = 373
Score = 125 bits (302), Expect = 7e-28
Identities = 66/182 (36%), Positives = 97/182 (53%), Gaps = 8/182 (4%)
Frame = +3
Query: 78 PNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKG------QCGHFVLEE--PMIM 233
P D+RLV+ P + +V + + GICGSD+H + G H + P+ +
Sbjct: 9 PRDVRLVEIDTPRVGPGDVRIAVAYCGICGSDLHEYADGPHAIPVDTPHPLSRRTAPLTL 68
Query: 234 GHEASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGN 413
GHE G V ++G V L GDRVA+EP C C +C++G Y+LC M F G
Sbjct: 69 GHEFCGTVVEVGEGVTALRAGDRVAVEPEYRCSQCAYCRSGSYNLCVSMGFAGLMG-DGG 127
Query: 414 LVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLLT 593
+ + A +LPD V++E+ A++EP AV +HA +RG + G V G GPIGLL
Sbjct: 128 MADFAVVPAYMLHRLPDGVSLEQAAVMEPAAVALHALRRGELRLGETCAVFGLGPIGLLL 187
Query: 594 ML 599
++
Sbjct: 188 IM 189
>UniRef50_Q8ELG9 Cluster: Sorbitol dehydrogenase; n=2;
Bacillaceae|Rep: Sorbitol dehydrogenase - Oceanobacillus
iheyensis
Length = 342
Score = 125 bits (301), Expect = 9e-28
Identities = 63/164 (38%), Positives = 95/164 (57%)
Frame = +3
Query: 108 IPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGSKVKNL 287
+PE+ +EV ++++ GICGSD+H + KG H + P+++GHE +G V ++GS V
Sbjct: 19 VPELKPNEVQIKVNVAGICGSDIHTY-KGL--HPFRKPPVVIGHEVAGEVVEVGSSVTKF 75
Query: 288 TVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDH 467
VGDRV +EP + E TG + + G + Y+ + KLPD
Sbjct: 76 KVGDRVTVEPQIGTGESEGVMTGNVNYSDTRLAPGMGDWLGTMAEYFASPEEQVIKLPDS 135
Query: 468 VTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLLTML 599
V+ ++G L+EPLAVG+HA +G V V +LGAGPIGLLT++
Sbjct: 136 VSYDQGVLVEPLAVGVHAAFKGDVQPTDRVAILGAGPIGLLTLI 179
>UniRef50_Q188T6 Cluster: Putative sugar-phosphate dehydrogenase;
n=2; Clostridium difficile|Rep: Putative sugar-phosphate
dehydrogenase - Clostridium difficile (strain 630)
Length = 350
Score = 124 bits (300), Expect = 1e-27
Identities = 65/176 (36%), Positives = 96/176 (54%), Gaps = 1/176 (0%)
Frame = +3
Query: 72 YKPNDLRLVQTPIPEISE-DEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEAS 248
Y D R+ +P+I E D+V++++ GICGSD+ + K H V E I+GHE S
Sbjct: 7 YGIRDTRVEDVDVPKILEKDDVIIKVKVAGICGSDISKYSKTG-PHMVGE---ILGHEFS 62
Query: 249 GVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYY 428
G VA++G +V++ +GDRVA+ P +PC C+ CK G Y C ++ + G Y
Sbjct: 63 GEVAQVGKEVRSFKIGDRVAVCPAMPCFECDECKKGLYSRCNNVAIIGNKELGGCFAEYT 122
Query: 429 KHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLLTM 596
K K+PD ++ E A LEP+ + H R G V+VLG GPIGL ++
Sbjct: 123 KVKERNLIKIPDEISYETAAALEPVCIAGHGLFRSEAKVGDTVVVLGTGPIGLFSI 178
>UniRef50_A4FHA7 Cluster: Zinc-binding dehydrogenase; n=1;
Saccharopolyspora erythraea NRRL 2338|Rep: Zinc-binding
dehydrogenase - Saccharopolyspora erythraea (strain NRRL
23338)
Length = 336
Score = 124 bits (298), Expect = 2e-27
Identities = 63/178 (35%), Positives = 103/178 (57%), Gaps = 2/178 (1%)
Frame = +3
Query: 63 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFV-LEEPMIMGH 239
A++ +P +R+ P E +V++++ GICG+D+H GHF P++ GH
Sbjct: 4 AIVDRPGSVRVGDVQDPSPGERDVVIKVGACGICGTDLHIAD----GHFPPTPYPIVPGH 59
Query: 240 EASGVVAKIGSKVKN-LTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNL 416
E +G V ++GS+ +GDRVA++P + C YC C++G +LC + V+G
Sbjct: 60 EFAGEVVELGSEAPGGFEIGDRVAVDPSLFCGYCTPCRSGHGNLCANWN-ATGDTVNGAF 118
Query: 417 VRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLL 590
Y A C+++PD +T E+GAL+EP++ +H ++ GV AG LV+GAG +GLL
Sbjct: 119 AEYVSVPAATCYRMPDEMTWEQGALVEPVSCAVHGVRQIGVEAGERFLVVGAGTMGLL 176
>UniRef50_A6LBP5 Cluster: Putative uncharacterized protein; n=1;
Parabacteroides distasonis ATCC 8503|Rep: Putative
uncharacterized protein - Parabacteroides distasonis
(strain ATCC 8503 / DSM 20701 / NCTC11152)
Length = 347
Score = 123 bits (297), Expect = 3e-27
Identities = 66/175 (37%), Positives = 93/175 (53%)
Frame = +3
Query: 66 LLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEA 245
+L+ DL+ P+P + DEVL+++ GICGSD+ K HF P ++GHE
Sbjct: 5 VLFGIGDLKYTNIPLPRLKSDEVLVKVKAAGICGSDIARVFKTGTYHF----PTVIGHEF 60
Query: 246 SGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRY 425
SGVV+ IGS +G RV++ P PC C CK Y LC + + + +G Y
Sbjct: 61 SGVVSDIGSSTYLSWLGKRVSVFPLKPCFKCNNCKNKEYELCSNYDYLGSR-CNGGFAEY 119
Query: 426 YKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLL 590
++PD V EE A+LEP AV +HA KR G G V+V+G G IG++
Sbjct: 120 VAVPVWNLLEIPDCVCYEEAAMLEPAAVALHALKRSGFKKGDTVVVIGPGTIGMI 174
>UniRef50_Q7SHA1 Cluster: Putative uncharacterized protein
NCU01905.1; n=1; Neurospora crassa|Rep: Putative
uncharacterized protein NCU01905.1 - Neurospora crassa
Length = 412
Score = 92.3 bits (219), Expect(2) = 6e-27
Identities = 43/106 (40%), Positives = 63/106 (59%), Gaps = 4/106 (3%)
Frame = +3
Query: 42 MATDNLTALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEE 221
MAT ++L+ DL + P+P +S +VL+ + G+CGSD+HY+ + G + E
Sbjct: 1 MATTIKASVLHGARDLSVESRPLPTLSPTDVLISIKSTGLCGSDLHYYTHFRNGDIQVHE 60
Query: 222 PMIMGHEASGVVAKIG----SKVKNLTVGDRVAIEPGVPCRYCEFC 347
P+ +GHE+SG++ IG S L VGDRVA+E G PC CE C
Sbjct: 61 PLTLGHESSGIITAIGSPSVSSEYGLNVGDRVALEVGQPCEACELC 106
Score = 51.2 bits (117), Expect(2) = 6e-27
Identities = 39/103 (37%), Positives = 48/103 (46%), Gaps = 23/103 (22%)
Frame = +3
Query: 351 TGRYHLCPDMIFCAT-------PPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAV 509
T RY++C M F ++ P G L H A +C KLP+ V GAL EPLAV
Sbjct: 136 TSRYNICRAMRFRSSAKGWPQFPHAQGTLQEVVAHPAKWCHKLPESVDYTLGALAEPLAV 195
Query: 510 GIHACKRGGV---------------SAGHV-VLVLGAGPIGLL 590
+HA R G+ A V VLV GAG +GLL
Sbjct: 196 AMHAAGRAGIPSCVPHSSSSMTSSRGAARVKVLVFGAGAVGLL 238
>UniRef50_A5I7E3 Cluster: Sorbitol dehydrogenase; n=7;
Clostridium|Rep: Sorbitol dehydrogenase - Clostridium
botulinum A str. ATCC 3502
Length = 349
Score = 122 bits (294), Expect = 6e-27
Identities = 64/172 (37%), Positives = 92/172 (53%)
Frame = +3
Query: 69 LYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEAS 248
L+ DLR + IP I E++VL+R+ VGICGSD+ H+ P I GHE S
Sbjct: 10 LHAIKDLRYEEVDIPTIGENDVLVRVKYVGICGSDMPRAMVSGAYHY----PTITGHEFS 65
Query: 249 GVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYY 428
G V +IG+ V ++ VG+R+A+ P +PC CEFCK G + LC F + G Y
Sbjct: 66 GEVVEIGNNVDDIKVGERIAVAPLIPCGECEFCKKGNFALCETYEFLGSRN-DGGFAEYV 124
Query: 429 KHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIG 584
+ + LP+ + E A +EP ++ A + G+ G V V+G GPIG
Sbjct: 125 RVPKENVLILPEDLDYETAAGIEPASISYQAMSKTGIKVGDTVAVVGCGPIG 176
>UniRef50_A0V2V9 Cluster: Alcohol dehydrogenase GroES-like; n=1;
Clostridium cellulolyticum H10|Rep: Alcohol
dehydrogenase GroES-like - Clostridium cellulolyticum
H10
Length = 356
Score = 122 bits (294), Expect = 6e-27
Identities = 61/178 (34%), Positives = 103/178 (57%), Gaps = 2/178 (1%)
Frame = +3
Query: 69 LYKPNDLRLVQTPIPEISED-EVLLRMDCVGICGSDV-HYWQKGQCGHFVLEEPMIMGHE 242
L+ P D+R IP IS D +V+++++ G+CGSD+ KG + P+++GHE
Sbjct: 10 LFAPGDVRCELIDIPVISADNQVIIKVEACGVCGSDIPRVMSKGAYRY-----PIVIGHE 64
Query: 243 ASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVR 422
SG V ++G+KVKN VGDRV P V C+ C++CK G+ C + + + + G +
Sbjct: 65 FSGEVVEVGTKVKNAKVGDRVTAMPLVNCKECDYCKIGQAITCDNYDYYGS-RIDGAMAE 123
Query: 423 YYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLLTM 596
Y + + +PD+V+ E A+ +P++V +HA ++ + AG +V G G IG +T+
Sbjct: 124 YIVVSEENIIHIPDNVSYYEAAMTDPVSVALHAVRKAEIEAGQTAVVFGLGAIGFITI 181
>UniRef50_Q9VDQ9 Cluster: CG4836-PC, isoform C; n=4; Eukaryota|Rep:
CG4836-PC, isoform C - Drosophila melanogaster (Fruit
fly)
Length = 1217
Score = 122 bits (294), Expect = 6e-27
Identities = 62/174 (35%), Positives = 99/174 (56%)
Frame = +3
Query: 57 LTALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMG 236
LT + P ++ +V P + +VL+R V + SD+H ++ G E M +G
Sbjct: 877 LTLRITNPYEISVVPFSKPRPKDFDVLIRTGSVAVSNSDIHVYENGNRDM----EAMSLG 932
Query: 237 HEASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNL 416
H+A+G+V ++G V++L VGDRV +E + C C+ CK G Y++C +++ +G L
Sbjct: 933 HDATGIVEELGRCVQHLHVGDRVVMESALSCGICDLCKKGLYNMCSGLVY------NGFL 986
Query: 417 VRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGP 578
Y H AD C +LP+ ++ME GAL + LA+G AC + V+ VL+LGA P
Sbjct: 987 STYQTHPADLCHRLPESISMEAGALTQTLALGCQACFKANVTPTSNVLILGACP 1040
>UniRef50_Q9S270 Cluster: Putative zinc-binding alcohol
dehydrogenase; n=3; Actinomycetales|Rep: Putative
zinc-binding alcohol dehydrogenase - Streptomyces
coelicolor
Length = 358
Score = 122 bits (293), Expect = 9e-27
Identities = 67/182 (36%), Positives = 89/182 (48%), Gaps = 5/182 (2%)
Frame = +3
Query: 66 LLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEA 245
+++ DLR+ P+ E L+ + G+CGSD+HYW+ G G F L EPM++GHE
Sbjct: 16 VIHGAGDLRVTDVPVRPPGPGEALVAVRYGGVCGSDLHYWRHGGVGDFHLREPMLLGHEV 75
Query: 246 SGVVAKIGS-KVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCAT----PPVHG 410
G V GS G VA+ P PC C C R ++C D + + P V G
Sbjct: 76 VGTVVAYGSPDTPGPAAGTSVAVHPATPCGVCPECVDRRRNVCRDTRYLGSAARFPHVQG 135
Query: 411 NLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLL 590
A LP + AL EPL+V +HA +R G AG VLV GAGPIG L
Sbjct: 136 GFAARIVVPAGQLRPLPAGLDPRRAALAEPLSVALHAVRRAGDPAGRHVLVTGAGPIGCL 195
Query: 591 TM 596
+
Sbjct: 196 VV 197
>UniRef50_Q2AGV2 Cluster: Zinc-containing alcohol dehydrogenase
superfamily; n=1; Halothermothrix orenii H 168|Rep:
Zinc-containing alcohol dehydrogenase superfamily -
Halothermothrix orenii H 168
Length = 336
Score = 121 bits (292), Expect = 1e-26
Identities = 59/177 (33%), Positives = 100/177 (56%)
Frame = +3
Query: 66 LLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEA 245
+ Y P ++++ IP+I E+EVL+++ GICG+D H ++ G +I+GHE
Sbjct: 5 VFYGPGNVKIEDKEIPKIDENEVLVKVKAAGICGTDRHIYR----GEAPARTQVILGHEN 60
Query: 246 SGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRY 425
+G + + G +V++L GD+V I+P + C C +C G HLC ++ +G Y
Sbjct: 61 AGEIIETGRQVRSLKKGDKVCIDPNIFCGQCYYCHRGEVHLCKELQAIGVTR-NGGFAEY 119
Query: 426 YKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLLTM 596
A +K+ ++V+ +E AL+EPLA +H G+ G V++LGAG IGL+ +
Sbjct: 120 LVAPATNVYKVKENVSYKEMALVEPLACCLHGIDLAGIRPGDFVVILGAGAIGLILL 176
>UniRef50_Q01PH7 Cluster: Alcohol dehydrogenase GroES domain
protein; n=3; Bacteria|Rep: Alcohol dehydrogenase GroES
domain protein - Solibacter usitatus (strain Ellin6076)
Length = 343
Score = 120 bits (290), Expect = 2e-26
Identities = 67/181 (37%), Positives = 97/181 (53%), Gaps = 4/181 (2%)
Frame = +3
Query: 66 LLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEA 245
LL + L +V+ P+P I D+VL+R+ GICGSDVH G+ G + P++MGHEA
Sbjct: 5 LLTQYMHLEMVEMPVPAIGADDVLVRVRACGICGSDVHGLD-GKTGRRI--PPLVMGHEA 61
Query: 246 SGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPP----VHGN 413
+G V + G+ V +L GDRV + V C C C G +LC + P HG
Sbjct: 62 AGEVVETGANVTDLRPGDRVTFDSTVYCGRCFHCTRGEVNLCDNREVLGVSPGPYRRHGA 121
Query: 414 LVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLLT 593
Y ++LPD ++ E+ AL+E ++V +HA V G +V+G+G IGLL
Sbjct: 122 FAEYVSVPRRIMYRLPDSLSYEQAALIEAVSVAVHAVNLTPVRLGDSAVVVGSGMIGLLA 181
Query: 594 M 596
M
Sbjct: 182 M 182
>UniRef50_A3I7D7 Cluster: Zinc-containing alcohol dehydrogenase,
long-chain; n=1; Bacillus sp. B14905|Rep:
Zinc-containing alcohol dehydrogenase, long-chain -
Bacillus sp. B14905
Length = 339
Score = 119 bits (287), Expect = 5e-26
Identities = 62/179 (34%), Positives = 96/179 (53%), Gaps = 1/179 (0%)
Frame = +3
Query: 63 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 242
A Y D+R+ + +P + V +++ GICGSD+H + G + ++GHE
Sbjct: 4 AKFYGMKDIRVEEAELPVLKNGMVKVKIAFAGICGSDLHEYVGGA---YAFRTQPVLGHE 60
Query: 243 ASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPD-MIFCATPPVHGNLV 419
SGVV ++ V + VGDRVA+EP +PC C CK G +LC + T + G
Sbjct: 61 FSGVVVEVAEGVTHTKVGDRVAVEPPIPCGKCANCKRGYSNLCKSGQSYGYT--ISGGFA 118
Query: 420 RYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLLTM 596
Y + + LP+ +++E GAL+EP AV +HA ++ + G + GAGPIGLL +
Sbjct: 119 EYAVVREENIYHLPEGMSLELGALVEPTAVAVHAVRQSQLKLGDTAAIFGAGPIGLLIL 177
>UniRef50_Q9K5Y6 Cluster: L-iditol 2-dehydrogenase; n=8;
Bacteria|Rep: L-iditol 2-dehydrogenase - Bacillus
halodurans
Length = 348
Score = 118 bits (285), Expect = 8e-26
Identities = 64/179 (35%), Positives = 93/179 (51%), Gaps = 8/179 (4%)
Frame = +3
Query: 84 DLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKG------QCGHFVLEE--PMIMGH 239
D+R+ P + +V +++ GICGSD+H + G H + EE P++MGH
Sbjct: 11 DVRVDDIAEPATLKGKVKIKVKWCGICGSDLHEYAAGPIFIPQNSPHSLTEEKAPIVMGH 70
Query: 240 EASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLV 419
E SG V ++G V GDRV +EP C C CK G+Y+LC + F G
Sbjct: 71 EFSGQVVEVGDGVTKCEEGDRVVVEPIFACGTCTACKQGKYNLCEQLGFLGLAGGGGGFS 130
Query: 420 RYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLLTM 596
Y K+PD V+ E+GAL+EP AV ++A ++ + G +V G GPIGLL +
Sbjct: 131 EYVTVDEHMVHKIPDTVSFEQGALVEPAAVALYAVRQSQFNVGDQAVVFGTGPIGLLVI 189
>UniRef50_A1UQB9 Cluster: Alcohol dehydrogenase GroES domain
protein; n=9; Actinomycetales|Rep: Alcohol dehydrogenase
GroES domain protein - Mycobacterium sp. (strain KMS)
Length = 343
Score = 118 bits (285), Expect = 8e-26
Identities = 65/175 (37%), Positives = 95/175 (54%)
Frame = +3
Query: 63 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 242
A+ + D+R+ + P P EV++ + GICG+D+H + G H +++GHE
Sbjct: 4 AIYHGREDVRIEELPDPSPRAGEVVIEVARAGICGTDLHEYIAGPM-HAA--PGVVIGHE 60
Query: 243 ASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVR 422
SG V +GS V+ T GDRV C C FCK G LC + F V+G L R
Sbjct: 61 YSGTVVGVGSGVREFTEGDRVCGVGVFGCGECGFCKQGAEALCGAVGFIGFA-VNGALAR 119
Query: 423 YYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGL 587
Y F++PD +++ E A++EP+A HA +R G++AG V + GAGPIGL
Sbjct: 120 YASLPTKALFRIPDEISLAEAAVVEPIASAYHAVRRSGLAAGGTVFIAGAGPIGL 174
>UniRef50_Q3IVK2 Cluster: Zinc-containing alcohol dehydrogenase;
n=1; Rhodobacter sphaeroides 2.4.1|Rep: Zinc-containing
alcohol dehydrogenase - Rhodobacter sphaeroides (strain
ATCC 17023 / 2.4.1 / NCIB 8253 / DSM158)
Length = 337
Score = 118 bits (284), Expect = 1e-25
Identities = 62/168 (36%), Positives = 94/168 (55%)
Frame = +3
Query: 87 LRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKI 266
LRL PI E DEVL+R+D ICG+D H + G F + P+++GHE +G V ++
Sbjct: 12 LRLTDLPIQEPGPDEVLIRIDSATICGTDQHILE----GKFWAKPPVVLGHEFAGYVERV 67
Query: 267 GSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADF 446
G +V+N GD V++EP V C C+ C+ G+ HLC D + ++G +Y D
Sbjct: 68 GERVQNCRPGDLVSVEPHVYCGCCKPCRLGKPHLCLDRLAWGI-NLNGGFEQYATVRMDT 126
Query: 447 CFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLL 590
+++P+ + EE AL E +H R GV G +V++LG G GL+
Sbjct: 127 VYQVPEGIGPEEAALGEITGCCMHGIDRVGVELGDLVVILGGGAAGLI 174
>UniRef50_Q927H5 Cluster: Lin2813 protein; n=16; Firmicutes|Rep:
Lin2813 protein - Listeria innocua
Length = 350
Score = 116 bits (280), Expect = 3e-25
Identities = 67/178 (37%), Positives = 93/178 (52%)
Frame = +3
Query: 63 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 242
A+LY+ N ++ Q +D+V + + VGICGSD+H Q + P +MGHE
Sbjct: 4 AVLYENNVIKAEQIDEATCGKDQVRVEVKAVGICGSDIHKMQT----RWKYPLPAVMGHE 59
Query: 243 ASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVR 422
+GVV +IGS+V N+ +GDRVA P PC C +CK G + LC D HG
Sbjct: 60 FAGVVTEIGSEVTNVAIGDRVAGIPLEPCMECNYCKAGDFALC-DNYRMVGSHFHGGFAE 118
Query: 423 YYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLLTM 596
AD + D + EEGA++EPLAV +H G V+V G G IG+L +
Sbjct: 119 NVVMKADNVISIGD-LDFEEGAMIEPLAVSMHGVLGIEPRLGDTVIVFGIGTIGILVV 175
>UniRef50_Q7CVQ9 Cluster: AGR_L_281p; n=7; Alphaproteobacteria|Rep:
AGR_L_281p - Agrobacterium tumefaciens (strain C58 /
ATCC 33970)
Length = 397
Score = 116 bits (279), Expect = 4e-25
Identities = 76/195 (38%), Positives = 106/195 (54%), Gaps = 12/195 (6%)
Frame = +3
Query: 51 DNLTAL-LYKPNDLRLVQTPIPEI-SEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEP 224
+N+ AL + DLR+ P+ +VL+R VGICG+D+H + G F+ EP
Sbjct: 39 ENMRALRFHAAKDLRIEDIAEPKRPGPGQVLVRNRFVGICGTDLHEYSYGPI--FIPTEP 96
Query: 225 ---------MIMGHEASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCE-FCKTGRYHLCP 374
I+GHE GVV IG V ++ VGDRV+I+P + R + F G +HL
Sbjct: 97 HPFTGAHGPQILGHEFGGVVEAIGDGVTSVNVGDRVSIQPLIMPRSGDYFADRGLFHLST 156
Query: 375 DMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHV 554
+ G + K+PD +T EE AL+EP AV ++AC RGGV+AG+
Sbjct: 157 QLALVGLSWDGGGMAEAALVNEYNVQKIPDEMTDEEAALVEPSAVAVYACDRGGVTAGNS 216
Query: 555 VLVLGAGPIGLLTML 599
VLV GAGPIG+LT+L
Sbjct: 217 VLVTGAGPIGMLTLL 231
>UniRef50_Q88S92 Cluster: L-iditol 2-dehydrogenase; n=7;
Firmicutes|Rep: L-iditol 2-dehydrogenase - Lactobacillus
plantarum
Length = 352
Score = 116 bits (278), Expect = 6e-25
Identities = 63/174 (36%), Positives = 103/174 (59%), Gaps = 2/174 (1%)
Frame = +3
Query: 81 NDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVA 260
+++ L Q PIPE++ D+VLL++ GICG+D+H + KGQ + V P+++GHE SG V
Sbjct: 12 DNMELKQIPIPEVTGDKVLLKVAYTGICGTDIHTF-KGQYANAV--TPLVLGHEFSGEVV 68
Query: 261 KIGSKVKNLTVGDRVAIEPGVPC-RYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHA 437
++G VK L GDRV E C +C+ Y+LCP+ + T +G++ Y
Sbjct: 69 EVGPDVKTLKPGDRVTSETTFATDGTCVYCQDKEYNLCPNRVGIGT-KANGSMANYVLTR 127
Query: 438 ADFCFKLPDHVTMEEGALLEPLAVGIHAC-KRGGVSAGHVVLVLGAGPIGLLTM 596
+ LPD+V+ + A+ EPLA +HA ++ + +L++G GP+GLL++
Sbjct: 128 EESAHILPDNVSYKMAAMSEPLASCVHAMYQKTPFTLHDTLLIMGPGPMGLLSL 181
>UniRef50_Q65L05 Cluster: YjmD; n=1; Bacillus licheniformis ATCC
14580|Rep: YjmD - Bacillus licheniformis (strain DSM 13
/ ATCC 14580)
Length = 338
Score = 116 bits (278), Expect = 6e-25
Identities = 56/175 (32%), Positives = 90/175 (51%)
Frame = +3
Query: 63 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 242
A++ KP + P PE + EVL+++ GICGSDVH++ + P I GHE
Sbjct: 4 AVMTKPYSIEFHDIPRPEPASGEVLVKIKAAGICGSDVHFYDGSNP---YAQYPQIFGHE 60
Query: 243 ASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVR 422
+G++ K G+ V+ + G+RV IEP +PC C C+ GR + C ++ + G
Sbjct: 61 LAGIIEKTGAGVRGRSAGERVVIEPAIPCGGCYPCRKGRTNACMNIDMIGSVR-RGGFAD 119
Query: 423 YYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGL 587
+ +P+ + AL EP ++G A +R + G +++LG GPIGL
Sbjct: 120 FIIVPETHVHPIPEQMDFATAALCEPFSIGAQAVRRADIQTGETIVILGMGPIGL 174
>UniRef50_Q5V6V7 Cluster: Zinc-binding dehydrogenase; n=1;
Haloarcula marismortui|Rep: Zinc-binding dehydrogenase -
Haloarcula marismortui (Halobacterium marismortui)
Length = 344
Score = 116 bits (278), Expect = 6e-25
Identities = 59/164 (35%), Positives = 88/164 (53%), Gaps = 2/164 (1%)
Frame = +3
Query: 111 PEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGSKVKNLT 290
P+ ++DEVL+++ +C +D H + G F E P+++GHE +G VA++G+ V
Sbjct: 20 PDPADDEVLVQVGACSVCMTDYHMYH----GTFAAETPLVLGHEGAGTVAEVGADVDRFA 75
Query: 291 VGDRVAIEPGVPCRYCEFCKTGRYHLCPD--MIFCATPPVHGNLVRYYKHAADFCFKLPD 464
VGDRVAI P VPC C +CK G HLC + I A + Y +
Sbjct: 76 VGDRVAINPTVPCNACSYCKKGETHLCENNTSIGGAGDTILDGAFAEYVRVPAINVEDIG 135
Query: 465 HVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLLTM 596
++ E AL EPLA +H ++ + G V ++GAGPIGLL +
Sbjct: 136 EMSFERAALAEPLACCVHGVEQADIKPGDSVGIIGAGPIGLLLL 179
>UniRef50_Q3A2I8 Cluster: Putative zinc-containing alcohol
dehydrogenase; n=1; Pelobacter carbinolicus DSM
2380|Rep: Putative zinc-containing alcohol dehydrogenase
- Pelobacter carbinolicus (strain DSM 2380 / Gra Bd 1)
Length = 327
Score = 115 bits (277), Expect = 7e-25
Identities = 63/178 (35%), Positives = 91/178 (51%)
Frame = +3
Query: 63 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 242
A L +P + + +TPIP EVL+R G+CGSD + G F + P+I GHE
Sbjct: 4 AQLVEPGKITIQETPIPSPKPGEVLIRTSVAGLCGSDHSVYH----GKFDVPLPVIPGHE 59
Query: 243 ASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVR 422
A G + ++G V N++VG RV I+P C C CK+G ++CP I +G L
Sbjct: 60 AIGTIVELGEGVTNVSVGQRVTIQPNFGCGVCPLCKSGHDNICPSKIRLGI-DTNGVLAE 118
Query: 423 YYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLLTM 596
Y + + + LP + E EPLAV +H + VLV+GAG +GLL +
Sbjct: 119 YVTAPSRYVWALPADLPDEVAVFTEPLAVAVHGVNMLPPNKDDRVLVMGAGIVGLLAL 176
>UniRef50_Q1IQV5 Cluster: Alcohol dehydrogenase, zinc-binding; n=2;
Acidobacteria|Rep: Alcohol dehydrogenase, zinc-binding -
Acidobacteria bacterium (strain Ellin345)
Length = 345
Score = 115 bits (277), Expect = 7e-25
Identities = 56/177 (31%), Positives = 96/177 (54%), Gaps = 1/177 (0%)
Frame = +3
Query: 63 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 242
A+LY D+R+ + P+P++ E E+L+++ CG+DV +++G ++ P + GHE
Sbjct: 4 AVLYGKEDVRIEKVPVPKVGEGEILVKVQVALTCGTDVKVYRRGYHARMIVP-PALFGHE 62
Query: 243 ASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVR 422
+G+V ++G VK L G RV PC C +C + +LC D++F + +
Sbjct: 63 LAGIVEEVGPGVKRLKKGMRVVALNSAPCGVCFYCSKHQENLCEDLLF--NNGAYAEYIL 120
Query: 423 YYKHAAD-FCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLL 590
K + +PD V+ +E A++EPLA + G+ G + V+GAGPIGL+
Sbjct: 121 IPKRIVEKNLLVIPDGVSFDEAAVIEPLACVLRGLHETGMEVGDTITVIGAGPIGLM 177
>UniRef50_A1D0R7 Cluster: Alcohol dehydrogenase; n=2;
Trichocomaceae|Rep: Alcohol dehydrogenase - Neosartorya
fischeri (strain ATCC 1020 / DSM 3700 / NRRL
181)(Aspergillus fischerianus (strain ATCC 1020 / DSM
3700 / NRRL 181))
Length = 364
Score = 115 bits (277), Expect = 7e-25
Identities = 65/191 (34%), Positives = 97/191 (50%), Gaps = 14/191 (7%)
Frame = +3
Query: 57 LTALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQC---------GHF 209
L L+ D+RL PIP+ D+V +R+ GICGSD+H +Q G H
Sbjct: 2 LALRLHGRQDIRLDTVPIPDCLSDQVRVRVAYCGICGSDIHEYQAGPILAPQPQETNPHS 61
Query: 210 VLEEPMIMGHEASGVVAKIGSKVKNLTVGDRVAI-----EPGVPCRYCEFCKTGRYHLCP 374
+ P+I+GHE SG V ++G+ V+ + +G +V + +P + C C GR++ C
Sbjct: 62 GAKLPVILGHEISGTVVEVGADVEGIRIGQKVVVNPLLADPQIQAEACTSCLRGRFNTCK 121
Query: 375 DMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHV 554
+ G A +PD+V++ AL EPLAV H +R G +AG
Sbjct: 122 RATYYGINAPGGGFSGEISVNAANIVPVPDNVSLRAAALAEPLAVACHMIERSGFAAGDN 181
Query: 555 VLVLGAGPIGL 587
+L+LGAGPIGL
Sbjct: 182 ILILGAGPIGL 192
>UniRef50_A6W9X6 Cluster: Alcohol dehydrogenase GroES domain
protein; n=3; Actinomycetales|Rep: Alcohol dehydrogenase
GroES domain protein - Kineococcus radiotolerans
SRS30216
Length = 349
Score = 114 bits (275), Expect = 1e-24
Identities = 68/183 (37%), Positives = 96/183 (52%), Gaps = 6/183 (3%)
Frame = +3
Query: 66 LLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEA 245
+++ DLR+ + P P+ EVLL ++ GICGSD+ YW+ G G LE P+++GHE
Sbjct: 5 VVHGAGDLRVEERPDPQPGPGEVLLALEWGGICGSDLAYWRHGASGTAQLEHPLVLGHEV 64
Query: 246 SGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCK--TGRYHLCPDMIFCAT----PPVH 407
+G VA +G V + VG V + P + GR +L P + + + P
Sbjct: 65 AGTVAALGPDVTGVEVGRAVTVHPATLVGEGDLPARIAGRTNLWPQVRYFGSAAFDPHTD 124
Query: 408 GNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGL 587
G ++ +D LP+ V GAL EPLAV +HA R G AG VLV GAGPIG
Sbjct: 125 GGFSQFRTVRSDQLRFLPEGVDTLRGALAEPLAVAMHAVGRAGSLAGRDVLVNGAGPIGS 184
Query: 588 LTM 596
L +
Sbjct: 185 LVV 187
>UniRef50_A1HSQ8 Cluster: Alcohol dehydrogenase GroES domain
protein; n=1; Thermosinus carboxydivorans Nor1|Rep:
Alcohol dehydrogenase GroES domain protein - Thermosinus
carboxydivorans Nor1
Length = 340
Score = 114 bits (274), Expect = 2e-24
Identities = 66/175 (37%), Positives = 97/175 (55%), Gaps = 1/175 (0%)
Frame = +3
Query: 75 KPNDLRLVQTPIPEISED-EVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASG 251
KP L + + P+P EV++++ GICGSDVH + GQ + P I+GHEA G
Sbjct: 8 KPGQLTVGERPMPAAPVGGEVVVKIKAAGICGSDVHIFH-GQ--NPFATYPRILGHEAVG 64
Query: 252 VVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYK 431
V + G++VK+L GDRVAI+ C C C++ R+++C ++ + G Y K
Sbjct: 65 EVYQAGAEVKDLKPGDRVAIDNVFSCGRCYACRSNRHNVCREVKVLGV-HIDGVFQEYIK 123
Query: 432 HAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLLTM 596
AD +KLP + E A +EP ++ A R GV+ VLV GAGPIGL+ +
Sbjct: 124 ITADKLYKLPADLPWEMAATVEPYSIAAEAVDRAGVTKDDTVLVCGAGPIGLVIL 178
>UniRef50_Q4LED8 Cluster: Dehydrogenase; n=1; uncultured
crenarchaeote 10-H-08|Rep: Dehydrogenase - uncultured
crenarchaeote 10-H-08
Length = 366
Score = 113 bits (273), Expect = 2e-24
Identities = 65/184 (35%), Positives = 96/184 (52%), Gaps = 5/184 (2%)
Frame = +3
Query: 63 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 242
A+ + P DLR++ P EVL+R CG+D+ + +G H P+IMGHE
Sbjct: 25 AVFHGPGDLRVMDVGRPSPGRGEVLVRTFVTLTCGTDLKMFLRG---HPYARPPVIMGHE 81
Query: 243 ASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDM----IFCATPPVHG 410
+GVV ++G +V + VGD V PC YC +CK GR++LC ++ I + +
Sbjct: 82 FAGVVVEVGEEVDWVNVGDEVVAANSAPCGYCIYCKLGRFNLCENLGETIIGFSVDGAYA 141
Query: 411 NLVRYYKHAADF-CFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGL 587
++ + F +KLP + ALLEPLA + + + G V V+GAGPIGL
Sbjct: 142 EYIKLPRRIVTFNLYKLPKGLEPRVAALLEPLACVVRGQRLIHIDVGDAVAVVGAGPIGL 201
Query: 588 LTML 599
L ML
Sbjct: 202 LHML 205
>UniRef50_Q9HWM8 Cluster: 2,3-butanediol dehydrogenase; n=24;
Proteobacteria|Rep: 2,3-butanediol dehydrogenase -
Pseudomonas aeruginosa
Length = 363
Score = 113 bits (272), Expect = 3e-24
Identities = 66/188 (35%), Positives = 102/188 (54%), Gaps = 9/188 (4%)
Frame = +3
Query: 63 ALLYKPNDLRLVQTPIP-EISEDEVLLRMDCVGICGSDVHYWQKG------QCGHFV--L 215
A+ + +D+R+ P+P E V +R+ GICGSD+H + G + H + L
Sbjct: 14 AVWHGRHDIRVEDVPLPAEPPPGWVQIRVHWCGICGSDLHEYLAGPVFIPVEAPHPLTGL 73
Query: 216 EEPMIMGHEASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCAT 395
++ I+GHE SG + ++G+ V VG VA + C C +C+ G Y++C ++ F
Sbjct: 74 KDQCILGHEFSGEIVRLGNGVTGFAVGQAVAADACQHCGTCYYCRHGLYNICENLAFTGL 133
Query: 396 PPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAG 575
+G Y A+ + LP E GAL+EPLAVG+HA K+ G G V+V+GAG
Sbjct: 134 MN-NGAFAEYVNVPANLLYALPAGFPSEAGALIEPLAVGMHAVKKAGSLLGQNVVVVGAG 192
Query: 576 PIGLLTML 599
IGL T++
Sbjct: 193 TIGLSTIM 200
>UniRef50_Q8DIZ5 Cluster: Sorbitol dehydrogenase; n=6;
Cyanobacteria|Rep: Sorbitol dehydrogenase -
Synechococcus elongatus (Thermosynechococcus elongatus)
Length = 366
Score = 113 bits (272), Expect = 3e-24
Identities = 66/201 (32%), Positives = 102/201 (50%), Gaps = 10/201 (4%)
Frame = +3
Query: 27 FRASDMATDNLTALLYKP-NDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCG 203
FR A ++ A +++ N L + PIPEI+ DEVL+R+ VG+C SD+ +
Sbjct: 7 FRGDAFAKVSMKAQVFRGVNQLSYEEIPIPEIAADEVLVRVRVVGLCQSDIK-----KIR 61
Query: 204 HFVLEEPMIMGHEASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMI 383
+ + E P I GHE +G +A +G V VG RV + +PC +C +C Y +C
Sbjct: 62 YPLYEPPRIFGHETAGEIAAVGDAVTGWQVGQRVVVMHHIPCMHCAYCLNENYSMCHVYK 121
Query: 384 FCATP----PVHGNLVRYYK---HAADF--CFKLPDHVTMEEGALLEPLAVGIHACKRGG 536
T P G Y K H + +PD ++ EE + +EP + A K+ G
Sbjct: 122 TVTTTAGFIPSGGGFAEYVKVPGHIVEHGGLIPIPDPISDEEASFVEPTNCCLKAVKKAG 181
Query: 537 VSAGHVVLVLGAGPIGLLTML 599
++ G VL+ GAGPIGL+ ++
Sbjct: 182 IAPGQTVLITGAGPIGLMFIM 202
>UniRef50_Q2RG84 Cluster: Alcohol dehydrogenase superfamily,
zinc-containing; n=1; Moorella thermoacetica ATCC
39073|Rep: Alcohol dehydrogenase superfamily,
zinc-containing - Moorella thermoacetica (strain ATCC
39073)
Length = 358
Score = 113 bits (271), Expect = 4e-24
Identities = 70/190 (36%), Positives = 94/190 (49%), Gaps = 8/190 (4%)
Frame = +3
Query: 42 MATDNLTAL-LYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLE 218
M + + AL L+ PND+RLV+ P+P+ EVL+R+ GICG+DV KG
Sbjct: 4 MIPEKMKALVLFGPNDVRLVEKPVPKPGPGEVLVRVAACGICGTDVKIITKGMPKMPPYG 63
Query: 219 EPMIMGHEASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDM------ 380
E GHE +G + +G V VGDRVAIE C CE C G+Y C +
Sbjct: 64 E-FTFGHEWAGTIVALGETVDEFQVGDRVAIEAHKGCGRCENCIDGKYTACLNYGRLDKG 122
Query: 381 IFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHAC-KRGGVSAGHVV 557
A V G Y + +K+PD++T E + ++A K GG AG V
Sbjct: 123 HRAAGMTVDGGFAEYAVQHVNSVYKIPDNITFNEATYVTTAGCALYAIDKSGGYIAGDTV 182
Query: 558 LVLGAGPIGL 587
LV+G GPIGL
Sbjct: 183 LVIGPGPIGL 192
>UniRef50_A0TC93 Cluster: Alcohol dehydrogenase GroES-like; n=15;
Proteobacteria|Rep: Alcohol dehydrogenase GroES-like -
Burkholderia ambifaria MC40-6
Length = 358
Score = 113 bits (271), Expect = 4e-24
Identities = 66/181 (36%), Positives = 98/181 (54%)
Frame = +3
Query: 57 LTALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMG 236
L+ + P LR P +E E+LLR+ VGICG+D+H + Q L+ P +MG
Sbjct: 25 LSIICESPGILRHEDRAPPSRAEGEILLRVQRVGICGTDMHIYSGNQP---YLQYPRVMG 81
Query: 237 HEASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNL 416
HE S +VA+ ++ GD V + P + C C C+ G+ + C ++ G L
Sbjct: 82 HELSAIVAEADPGA-HVAPGDAVYVMPYLSCGQCIACRQGKTNCCVNIKVLGVHR-DGAL 139
Query: 417 VRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLLTM 596
Y A F K + VT+++ A++E LA+G HA +R VSAG +LV+GAGPIG+ M
Sbjct: 140 TEYLSVPAQFVHKA-EGVTLDQAAMIEFLAIGAHAVRRAAVSAGQRILVVGAGPIGMAAM 198
Query: 597 L 599
L
Sbjct: 199 L 199
>UniRef50_A4J9K3 Cluster: Alcohol dehydrogenase GroES domain
protein; n=1; Desulfotomaculum reducens MI-1|Rep:
Alcohol dehydrogenase GroES domain protein -
Desulfotomaculum reducens MI-1
Length = 345
Score = 112 bits (270), Expect = 5e-24
Identities = 65/180 (36%), Positives = 94/180 (52%), Gaps = 5/180 (2%)
Frame = +3
Query: 66 LLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEA 245
LL + N+L L IP EVL+++ GIC +D+ ++ GH L P I+GHE
Sbjct: 5 LLEQANNLVLKTIEIPRCKAGEVLVKVAACGICRTDMKSYR---LGHRDLHLPRILGHEI 61
Query: 246 SGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRY 425
+G V +IG+ V + G+RV + PG+PC C C TG HLCP++ G Y
Sbjct: 62 AGTVVEIGAGVTEVHCGERVQVSPGLPCGVCPNCLTGLNHLCPNIEIMGF-HYDGGFAEY 120
Query: 426 Y-----KHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLL 590
A KLPDH +E AL EPLA I+ + + +G +++ GAGP+G+L
Sbjct: 121 VLIPSKGVKAKVLNKLPDHFPIELAALTEPLACCINIQESMDIGSGDTIIIFGAGPVGIL 180
>UniRef50_A1R5Y9 Cluster: L-threonine 3-dehydrogenase; n=1;
Arthrobacter aurescens TC1|Rep: L-threonine
3-dehydrogenase - Arthrobacter aurescens (strain TC1)
Length = 347
Score = 112 bits (270), Expect = 5e-24
Identities = 60/164 (36%), Positives = 88/164 (53%), Gaps = 2/164 (1%)
Frame = +3
Query: 111 PEISEDEVLLRMDCVGICGSDVHYWQKGQCGH-FVLEEPMIMGHEASGVVAKIGSKVKNL 287
P+ +E V++ + +CG+D ++ F L P+++GHE +G V +IG V L
Sbjct: 22 PKATEGSVVIEVGAASLCGTDRELYEWTPSAQAFNLNLPVVLGHEGAGTVVEIGPGVTGL 81
Query: 288 TVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDH 467
VGD+VA+E + C C C+TG H C + + G Y D C KLP
Sbjct: 82 KVGDQVALESHLTCGQCFPCRTGDAHTC-ERTGILGMHIDGVFAEYAAVPQDICVKLPTG 140
Query: 468 VTMEEGALLEPLAVGIHACKRGGVS-AGHVVLVLGAGPIGLLTM 596
+++E GALLE V +HA +R S AG VLV GAGP+GL+ +
Sbjct: 141 LSLESGALLEAAGVAVHAIQRANYSVAGRAVLVSGAGPVGLVVV 184
>UniRef50_P39346 Cluster: L-idonate 5-dehydrogenase; n=17;
Gammaproteobacteria|Rep: L-idonate 5-dehydrogenase -
Escherichia coli (strain K12)
Length = 343
Score = 112 bits (270), Expect = 5e-24
Identities = 60/149 (40%), Positives = 78/149 (52%), Gaps = 4/149 (2%)
Frame = +3
Query: 156 GICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGSKVKNLTVGDRVAIEPGVPCRY 335
GICGSD+HY+Q+G+ G+F+++ PM++GHE G V I S L G VAI P PC +
Sbjct: 38 GICGSDLHYYQEGKVGNFMIKAPMVLGHEVIGKV--IHSDSSELHEGQTVAINPSKPCGH 95
Query: 336 CEFCKTGRYHLCPDMIFCAT----PPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPL 503
C++C + C DM F + P V G RY C P + A EPL
Sbjct: 96 CKYCIEHNENQCTDMRFFGSAMYFPHVDGGFTRYKMVETSQCVPYPAKADEKVMAFAEPL 155
Query: 504 AVGIHACKRGGVSAGHVVLVLGAGPIGLL 590
AV IHA + G G V + G GPIG L
Sbjct: 156 AVAIHAAHQAGELQGKRVFISGVGPIGCL 184
>UniRef50_Q9KGB7 Cluster: Sorbitol dehydrogenase; n=28;
Bacillales|Rep: Sorbitol dehydrogenase - Bacillus
halodurans
Length = 354
Score = 112 bits (269), Expect = 7e-24
Identities = 66/178 (37%), Positives = 93/178 (52%), Gaps = 2/178 (1%)
Frame = +3
Query: 69 LYKPNDLRLVQTPIPEIS-EDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEA 245
LY DLR +TP P I +D++++++ VGICGSD+ ++K G +V M GHE
Sbjct: 6 LYGIQDLRFEETPAPSIEHDDDIIIKVKAVGICGSDLSRYKK--LGPYV--PGMTFGHEF 61
Query: 246 SGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDM-IFCATPPVHGNLVR 422
+G V KIG V ++GDRVA P C C +C+ G C + + A P G
Sbjct: 62 AGEVVKIGRSVTGFSIGDRVAACPTYTCGQCRYCQLGEPTRCERLSVIGARHP--GAYAE 119
Query: 423 YYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLLTM 596
Y K A LP+ V +E AL+EP +V H R + G V ++G G IGLL +
Sbjct: 120 YVKLPAKHVIPLPNVVNYDEAALIEPASVVAHGFYRTNIKPGASVAIMGVGSIGLLAV 177
>UniRef50_Q5WC08 Cluster: Galactitol-1-phosphate 5-dehydrogenase;
n=1; Bacillus clausii KSM-K16|Rep:
Galactitol-1-phosphate 5-dehydrogenase - Bacillus
clausii (strain KSM-K16)
Length = 352
Score = 112 bits (269), Expect = 7e-24
Identities = 63/168 (37%), Positives = 98/168 (58%)
Frame = +3
Query: 96 VQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGSK 275
++TP+P+ EDE L+++ GICGSD+ + G+ ++ P+++GHE SG V +G+
Sbjct: 17 IETPVPK--EDEALIKVAYCGICGSDLARYFDGKVHNY----PIVLGHEFSGTVEAVGAS 70
Query: 276 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFK 455
V ++ VGDRV + P +P + F + G L F + +G + Y A+
Sbjct: 71 VDSVAVGDRVVVAPLLPNKDDPFMQKGSPALSSSYSFLGSRE-NGAMAEYVVVKAENLLV 129
Query: 456 LPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLLTML 599
LP+ VT+ E AL+EPL V IH +R + AG V VLGAG IG++T+L
Sbjct: 130 LPETVTLAEAALIEPLTVAIHGIERIVLPAGEHVCVLGAGTIGIMTIL 177
>UniRef50_A1SFU6 Cluster: Alcohol dehydrogenase, zinc-binding domain
protein; n=1; Nocardioides sp. JS614|Rep: Alcohol
dehydrogenase, zinc-binding domain protein -
Nocardioides sp. (strain BAA-499 / JS614)
Length = 351
Score = 112 bits (269), Expect = 7e-24
Identities = 66/189 (34%), Positives = 95/189 (50%), Gaps = 8/189 (4%)
Frame = +3
Query: 48 TDNLTALLYK-PNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEP 224
T + AL+ + PN L + + P+PE +EVL R+ V ICG+D H G + + P
Sbjct: 2 TQIMQALVVREPNVLEIAEVPVPEPGRNEVLARVRSVSICGTDAHLINGDYPGFWPPQFP 61
Query: 225 MIMGHEASGVVAKIGSKVKNL--TVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATP 398
GHE +G V +G VGDRVA C C+ C G+Y+LC + A
Sbjct: 62 FTPGHEWAGDVVALGEGADTFGWRVGDRVAGTSHSACGACQKCVEGQYNLCENYGRPALH 121
Query: 399 PVHGNLVR-----YYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLV 563
+G+ + Y H F+LPD V+ + GAL +P ++ +H +RG + G V V
Sbjct: 122 AQYGHNAQGVNATYAVHNVKSIFRLPDEVSFDVGALADPASIALHVARRGNIKPGDTVAV 181
Query: 564 LGAGPIGLL 590
GAG IGLL
Sbjct: 182 TGAGAIGLL 190
>UniRef50_A0UVE8 Cluster: Alcohol dehydrogenase GroES-like; n=1;
Clostridium cellulolyticum H10|Rep: Alcohol
dehydrogenase GroES-like - Clostridium cellulolyticum
H10
Length = 348
Score = 112 bits (269), Expect = 7e-24
Identities = 66/176 (37%), Positives = 89/176 (50%)
Frame = +3
Query: 66 LLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEA 245
+L+ +DLR + P + EVL+R+ GICGSD+ G HF P+++GHE
Sbjct: 5 VLHARDDLRYEEILTPVPVKGEVLVRVKATGICGSDIPR-VLGDGAHFF---PIVLGHEF 60
Query: 246 SGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRY 425
SG VA+IG V ++ VGDRVA P VPC C C+ G Y LC F + G+ Y
Sbjct: 61 SGEVAEIGEGVTSVAVGDRVAGVPLVPCLKCGDCQKGDYALCKHYSFIGSRE-SGSFAEY 119
Query: 426 YKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLLT 593
K K D V+ E+GA EP V +H G V +LG G +G+ T
Sbjct: 120 VKMPERNVVKFNDSVSFEQGAFFEPATVALHGLLCADYRGGEDVAILGGGTVGMFT 175
>UniRef50_Q1Q2R9 Cluster: Similar to sorbitol dehydrogenase; n=1;
Candidatus Kuenenia stuttgartiensis|Rep: Similar to
sorbitol dehydrogenase - Candidatus Kuenenia
stuttgartiensis
Length = 339
Score = 111 bits (268), Expect = 9e-24
Identities = 60/178 (33%), Positives = 92/178 (51%), Gaps = 2/178 (1%)
Frame = +3
Query: 63 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 242
A+ Y ND+R+ + P P+I E+L+++ GICGSDV W + + + P+++GHE
Sbjct: 4 AMYYNNNDVRIEEMPTPQIGPGELLVKIFASGICGSDVMEWYR------IKKAPLVLGHE 57
Query: 243 ASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDM-IFCATPPVHGNLV 419
+G + IG VK VGDRV + VPC C +C G + +C + P +
Sbjct: 58 IAGEIVAIGDAVKQFKVGDRVTVAHHVPCNTCHYCLNGHHSVCDTLRTTNFYPGGFAEFL 117
Query: 420 RYYKHAAD-FCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLL 590
R + D F LP ++ +EG +EPLA I + G +LV+G+G GLL
Sbjct: 118 RVPQINVDRGTFILPQEMSYDEGTFVEPLACSIRGQRLSNFKPGQSLLVIGSGISGLL 175
>UniRef50_Q025V7 Cluster: Alcohol dehydrogenase GroES domain
protein; n=2; Bacteria|Rep: Alcohol dehydrogenase GroES
domain protein - Solibacter usitatus (strain Ellin6076)
Length = 339
Score = 111 bits (267), Expect = 1e-23
Identities = 55/157 (35%), Positives = 83/157 (52%)
Frame = +3
Query: 129 EVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGSKVKNLTVGDRVA 308
+V + ++ GICG+D+H + L P +MGHE SG +A +G V GDRV
Sbjct: 26 QVQINVEFCGICGTDLHLFHGAMAHRLTL--PHVMGHEMSGTLAAVGEGVAGWQAGDRVT 83
Query: 309 IEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGA 488
+ P PC C C+ G H+C ++ F G L + A +LPD +++ EGA
Sbjct: 84 VRPLDPCGTCPACRMGHSHICHNLKFIGI-DTPGALQGMWTVPAHTLHRLPDSLSLREGA 142
Query: 489 LLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLLTML 599
++EP+AV H + + AG +V+G GPIG+L L
Sbjct: 143 MVEPIAVACHDVRMSELQAGEFAVVIGGGPIGILIAL 179
>UniRef50_A1UPQ2 Cluster: Alcohol dehydrogenase GroES domain
protein; n=10; Mycobacterium|Rep: Alcohol dehydrogenase
GroES domain protein - Mycobacterium sp. (strain KMS)
Length = 341
Score = 111 bits (267), Expect = 1e-23
Identities = 57/169 (33%), Positives = 87/169 (51%)
Frame = +3
Query: 81 NDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVA 260
ND+ L P P + EV++ + G+CG+D+H + G + P+++GHE SG +
Sbjct: 10 NDVGLTSVPDPAPQDGEVIIEVAATGLCGTDLHEYVAGPT---FSQPPVVLGHEVSGRIV 66
Query: 261 KIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAA 440
++G+ V +G A+ P C C +C YHLC + +G L Y +
Sbjct: 67 EVGAGVDQSRIGQGAAVIPMDFCGSCHYCHRSLYHLCQRPGWIGFTR-NGGLANYVAVPS 125
Query: 441 DFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGL 587
++PD V +EE AL EP AV HA +R + G V+VLGAG +GL
Sbjct: 126 RLAVRVPDVVDLEEAALTEPTAVAFHAVRRAELLLGETVMVLGAGALGL 174
>UniRef50_A1DNE9 Cluster: Alcohol dehydrogenase; n=4;
Trichocomaceae|Rep: Alcohol dehydrogenase - Neosartorya
fischeri (strain ATCC 1020 / DSM 3700 / NRRL
181)(Aspergillus fischerianus (strain ATCC 1020 / DSM
3700 / NRRL 181))
Length = 375
Score = 111 bits (267), Expect = 1e-23
Identities = 60/177 (33%), Positives = 93/177 (52%), Gaps = 7/177 (3%)
Frame = +3
Query: 78 PNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQC-----GHFVL--EEPMIMG 236
P D+R+ + P + +V LR VGICGSD+H + G H + P+ +G
Sbjct: 30 PGDIRIEEIDEPTCGKGQVKLRPAFVGICGSDLHEYSAGPVLIPKEPHKITGTSYPVTLG 89
Query: 237 HEASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNL 416
HE +G+V ++G V +L+ G R + P + R C CK G + C ++ F G +
Sbjct: 90 HEFAGIVEEVGEGVTHLSPGQRAVVRPTIFDRQCCSCKLGYEYCCENIGFIGLSGYGGGM 149
Query: 417 VRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGL 587
++ A+ + LPD+V++E AL+EPLAV HA G V+V+G GPIG+
Sbjct: 150 AKHTVAPAEHFYPLPDNVSLEAAALIEPLAVAWHAVNLSPFKGGDNVMVVGGGPIGI 206
>UniRef50_Q57517 Cluster: Uncharacterized zinc-type alcohol
dehydrogenase-like protein HI0053; n=18;
Gammaproteobacteria|Rep: Uncharacterized zinc-type
alcohol dehydrogenase-like protein HI0053 - Haemophilus
influenzae
Length = 342
Score = 111 bits (267), Expect = 1e-23
Identities = 59/178 (33%), Positives = 103/178 (57%), Gaps = 1/178 (0%)
Frame = +3
Query: 69 LYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEAS 248
L KPN++ + + P PE S+++VL++++ +GICGSD+ + +G + ++ P I+GHE
Sbjct: 10 LEKPNNVVVKEVPYPEKSDNDVLIQVESMGICGSDIGAY-RGT--NPLVTYPRILGHEIV 66
Query: 249 GVVAKIGSKVKN-LTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRY 425
G V + G + + + VGDRV ++P V C C C GR + C + + G +
Sbjct: 67 GRVIESGIGMSDGVRVGDRVIVDPYVCCGQCYPCSIGRTNCCESLKVIGVH-IDGGMQEV 125
Query: 426 YKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLLTML 599
+H A K+PD++ + + L EPL + +HA R + +G ++++GAG IGL+ L
Sbjct: 126 IRHPAHLLTKVPDNLPIHQLPLAEPLTIALHALHRTTLKSGEHIVIIGAGAIGLMAAL 183
>UniRef50_UPI0000553E21 Cluster: Zinc-containing alcohol
dehydrogenase superfamily; n=1; Paracoccus denitrificans
PD1222|Rep: Zinc-containing alcohol dehydrogenase
superfamily - Paracoccus denitrificans PD1222
Length = 237
Score = 111 bits (266), Expect = 2e-23
Identities = 66/181 (36%), Positives = 99/181 (54%), Gaps = 9/181 (4%)
Frame = +3
Query: 84 DLRLVQTPIP-EISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEP-------MIMGH 239
DLR+ P P E + DEV++ GICG+D+H + G FV ++ ++GH
Sbjct: 11 DLRVEDIPQPTEPAADEVVIENRFAGICGTDLHEYAYGPI--FVPKDAATGAVAAQVLGH 68
Query: 240 EASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEF-CKTGRYHLCPDMIFCATPPVHGNL 416
E G V K+G V ++ VGDRV+++P + R ++ G+++L M + G +
Sbjct: 69 EYGGTVVKVGRDVTHVKVGDRVSVQPFITPRGGDYYTDRGQFNLSDAMALAGLSWIGGGM 128
Query: 417 VRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLLTM 596
+KLPD +T E+ AL+EP+AV ++ RGGV G VLV GAGPIGLL +
Sbjct: 129 AESSLLKGYNVYKLPDQMTDEDAALVEPVAVAVYGVDRGGVKPGDAVLVTGAGPIGLLAL 188
Query: 597 L 599
L
Sbjct: 189 L 189
>UniRef50_A4XHJ7 Cluster: Alcohol dehydrogenase GroES domain
protein; n=1; Caldicellulosiruptor saccharolyticus DSM
8903|Rep: Alcohol dehydrogenase GroES domain protein -
Caldicellulosiruptor saccharolyticus (strain ATCC 43494
/ DSM 8903)
Length = 324
Score = 111 bits (266), Expect = 2e-23
Identities = 59/178 (33%), Positives = 95/178 (53%)
Frame = +3
Query: 63 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 242
A+ Y DLR+ + +P + + E+L+++ GICG+DVH + G+ G + P+I+GHE
Sbjct: 4 AVFYGKRDLRVEEFDLPPLKQGEILVKVKACGICGTDVHIF-NGEKGSAKVTPPIILGHE 62
Query: 243 ASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVR 422
G V + S + VGD+V+I+P + C C FC++G+ LC + ++G
Sbjct: 63 FCGEVVETKSSL--FKVGDKVSIDPNIYCGVCRFCRSGKVQLCESLTALGV-NLNGGFAE 119
Query: 423 YYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLLTM 596
Y D + EE AL EPLA +H K+ + VL++G GPIGL+ +
Sbjct: 120 YAIVPEKQAILFED-IEFEEAALAEPLACCLHGIKKLEIKPIDKVLIIGLGPIGLIML 176
>UniRef50_Q8ZJN2 Cluster: L-threonine 3-dehydrogenase; n=41;
Bacteria|Rep: L-threonine 3-dehydrogenase - Yersinia
pestis
Length = 341
Score = 111 bits (266), Expect = 2e-23
Identities = 54/166 (32%), Positives = 88/166 (53%)
Frame = +3
Query: 93 LVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGS 272
+ P PE+ +++++++ ICG+DVH + + + PM++GHE G V IG
Sbjct: 15 MTDVPQPELGHNDIMIKIRKTAICGTDVHIYNWDEWSQKTIPVPMVVGHEYVGEVVAIGQ 74
Query: 273 KVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCF 452
+VK +GDRV+ E + C +C C+ GR HLC + + G+ Y A F
Sbjct: 75 EVKGFNIGDRVSGEGHITCGHCRNCRGGRTHLCRNTVGVGVNR-PGSFAEYLVIPAFNAF 133
Query: 453 KLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLL 590
K+PD+++ E A+ +P +H + G VLV GAGPIG++
Sbjct: 134 KIPDNISDELAAIFDPFGNAVHTALSFDL-VGEDVLVSGAGPIGIM 178
>UniRef50_UPI000050F926 Cluster: COG1063: Threonine dehydrogenase
and related Zn-dependent dehydrogenases; n=1;
Brevibacterium linens BL2|Rep: COG1063: Threonine
dehydrogenase and related Zn-dependent dehydrogenases -
Brevibacterium linens BL2
Length = 328
Score = 110 bits (265), Expect = 2e-23
Identities = 61/183 (33%), Positives = 92/183 (50%), Gaps = 3/183 (1%)
Frame = +3
Query: 60 TALLYKPNDLRLVQTPIPE--ISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEE-PMI 230
+A + P + +V +P+ + ++ +RM VGICG+D Q G + P
Sbjct: 3 SAEITAPGRVEIVDRSLPQGLVGRGDLRIRMLAVGICGTD----QTLATGRRTPPQLPWR 58
Query: 231 MGHEASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHG 410
+GHE G +A++G VGDRVA+EP + C CE+C+ G C + G
Sbjct: 59 LGHEGIGEIAEVGPGACGFAVGDRVALEPNITCGRCEYCRRGMTSACTSRLSAGVLTQPG 118
Query: 411 NLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLL 590
L H ++FC +L H+++E EPLAV A +R + VLVLGAG GLL
Sbjct: 119 FLAEVVDHPSEFCHRLDAHMSLERAVCAEPLAVAASAIRRTDLQGSETVLVLGAGAQGLL 178
Query: 591 TML 599
++L
Sbjct: 179 SIL 181
>UniRef50_Q65L02 Cluster: Putative uncharacterized protein; n=1;
Bacillus licheniformis ATCC 14580|Rep: Putative
uncharacterized protein - Bacillus licheniformis (strain
DSM 13 / ATCC 14580)
Length = 337
Score = 110 bits (265), Expect = 2e-23
Identities = 60/175 (34%), Positives = 92/175 (52%), Gaps = 1/175 (0%)
Frame = +3
Query: 75 KPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHF-VLEEPMIMGHEASG 251
KP ++ +PE+ + E L+R+ +GICG+D H + CG P ++GHE SG
Sbjct: 8 KPYRFKMTDVKMPELKDGEALVRIKRIGICGTDFHAY----CGRQPFFSYPRVLGHELSG 63
Query: 252 VVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYK 431
+ I + L GD+V+I P + C C C+ GR + C ++ G + Y
Sbjct: 64 EIVSIDNSGGTLKPGDQVSIIPYLECGACIACRNGRPNCCVNLNVLGVH-TDGGMREYIN 122
Query: 432 HAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLLTM 596
AD K + +T+ E A++E L++G HA +R + G VLV+GAGPIGL M
Sbjct: 123 VPADHLLKT-EGLTLSEAAVVECLSIGAHAAERANIKKGETVLVVGAGPIGLSVM 176
>UniRef50_A6VRA2 Cluster: Alcohol dehydrogenase GroES domain
protein; n=2; Oceanospirillales|Rep: Alcohol
dehydrogenase GroES domain protein - Marinomonas sp.
MWYL1
Length = 340
Score = 110 bits (265), Expect = 2e-23
Identities = 63/169 (37%), Positives = 91/169 (53%)
Frame = +3
Query: 81 NDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVA 260
ND L+ T P EVL++ GICGSD+H GQ FV + P I GHE SGVVA
Sbjct: 10 NDYALIDTLQPVAEAGEVLIKTAFAGICGSDLHIIH-GQ-NPFV-QFPRITGHEFSGVVA 66
Query: 261 KIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAA 440
+G V ++ +GD+V ++P + C C C+ GR+++C + +G + A
Sbjct: 67 AVGEGVTHVKIGDKVCVDPVISCGECYACRAGRFNVCAKLQVFGVHR-NGGFGEFTSAPA 125
Query: 441 DFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGL 587
LPD+VT+E+ AL+EP ++ + R G +LV GAG IGL
Sbjct: 126 SNVLVLPDNVTLEQAALVEPYSIATNVLSRMEPIPGDTLLVYGAGVIGL 174
>UniRef50_UPI00015B5FCF Cluster: PREDICTED: similar to putative
zinc-containing alcohol dehydrogenase; n=1; Nasonia
vitripennis|Rep: PREDICTED: similar to putative
zinc-containing alcohol dehydrogenase - Nasonia
vitripennis
Length = 339
Score = 109 bits (263), Expect = 4e-23
Identities = 68/173 (39%), Positives = 93/173 (53%), Gaps = 5/173 (2%)
Frame = +3
Query: 87 LRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLE--EPMIMGHEASGVVA 260
L L + IP+ +DEVL+R+ GICG+D+H + G F + EP+I GHE G V
Sbjct: 13 LTLQKASIPKPKDDEVLIRVAYSGICGTDLHILE----GTFPCKQNEPLIPGHEFCGTVE 68
Query: 261 KIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPV--HGNLVRYYKH 434
+G VKN VG RV ++P C C+ C G YHLC + +T + +G +
Sbjct: 69 AVGVSVKNFKVGQRVTVDPNSGCSMCDDCHVGCYHLCVNGGVNSTIGIFRNGGWATHCCV 128
Query: 435 AADFCFKLPDHVTMEEGALLEPLAVGIHACKR-GGVSAGHVVLVLGAGPIGLL 590
+ +P+ V ME+ AL EPL+ H KR + G VLVLGAG IGLL
Sbjct: 129 PEVQVYHVPEGVEMEQAALSEPLSCLAHGWKRMNPIHVGQKVLVLGAGIIGLL 181
>UniRef50_Q8KQG6 Cluster: Mannitol dehydrogenase; n=12;
Bacteria|Rep: Mannitol dehydrogenase - Leuconostoc
mesenteroides
Length = 338
Score = 109 bits (263), Expect = 4e-23
Identities = 55/160 (34%), Positives = 90/160 (56%)
Frame = +3
Query: 111 PEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGSKVKNLT 290
P++ +EVL+ GICG+D H G G P+++GHE SGVVA+IGS V N+
Sbjct: 20 PKVLPNEVLIHTAFAGICGTD-HALYAGLPGSADAVPPIVLGHENSGVVAEIGSAVTNVK 78
Query: 291 VGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHV 470
VGDRV ++P + C C++C+T R LC ++ G ++ A + +PD+V
Sbjct: 79 VGDRVTVDPNIYCGQCKYCRTARPELCENLSAVGVTR-DGGFEEFFTAPASVVYPIPDNV 137
Query: 471 TMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLL 590
+++ A++EP++ +H + V+ LV+G G +G L
Sbjct: 138 SLKSAAVVEPISCAVHGIQLLKVTPYQKALVIGDGFMGEL 177
>UniRef50_A6W685 Cluster: Alcohol dehydrogenase zinc-binding domain
protein; n=1; Kineococcus radiotolerans SRS30216|Rep:
Alcohol dehydrogenase zinc-binding domain protein -
Kineococcus radiotolerans SRS30216
Length = 347
Score = 109 bits (262), Expect = 5e-23
Identities = 66/182 (36%), Positives = 91/182 (50%), Gaps = 6/182 (3%)
Frame = +3
Query: 69 LYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEAS 248
++ P DLR+ + PE + EVL+R+ GICGSD+HY G+ G +V+ EP+++GHE
Sbjct: 6 VHAPGDLRVEEVDAPEPAPGEVLVRIVYGGICGSDLHYAADGRNGAYVVTEPLVLGHEVV 65
Query: 249 GVVAKIGSKVKNL-TVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVH----GN 413
GVV + G G RVA+ P PC HL P + + H G
Sbjct: 66 GVVERAGPDTPAAPPAGTRVAVHPATPCAPAGAAAPTGLHLRPGGTYLGSASTHPHTQGG 125
Query: 414 LVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKR-GGVSAGHVVLVLGAGPIGLL 590
+ +LP + + L EPLAV +HA R G AG VLV GAGPIG+L
Sbjct: 126 FTGLLAVGVERLRELPAALPLRRAVLAEPLAVALHAVGRLEGRVAGARVLVSGAGPIGVL 185
Query: 591 TM 596
+
Sbjct: 186 AV 187
>UniRef50_P39713 Cluster: Zinc-type alcohol dehydrogenase-like
protein YAL061W; n=8; Saccharomycetales|Rep: Zinc-type
alcohol dehydrogenase-like protein YAL061W -
Saccharomyces cerevisiae (Baker's yeast)
Length = 417
Score = 109 bits (262), Expect = 5e-23
Identities = 64/184 (34%), Positives = 96/184 (52%), Gaps = 23/184 (12%)
Frame = +3
Query: 117 ISEDEVLLRMDCVGICGSDVHYWQKG-----QCGHF--VLEEPM--IMGHEASGVVAKIG 269
++ DE+++ ++ GICG+D+H + G + GH + P+ MGHE +G V ++G
Sbjct: 24 VAPDELVIDIEWCGICGTDLHEYTDGPIFFPEDGHTHEISHNPLPQAMGHEMAGTVLEVG 83
Query: 270 SKVKNLTVGDRVAIEPGVPCR--------------YCEFCKTGRYHLCPDMIFCATPPVH 407
VKNL VGD+V +EP CR +C CK G Y++C + C
Sbjct: 84 PGVKNLKVGDKVVVEPTGTCRDRYRWPLSPNVDKEWCAACKKGYYNICSYLGLCGAGVQS 143
Query: 408 GNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGL 587
G C+K+PD V ++ AL++PLAV HA + AG L++GAGPIGL
Sbjct: 144 GGFAERVVMNESHCYKVPDFVPLDVAALIQPLAVCWHAIRVCEFKAGSTALIIGAGPIGL 203
Query: 588 LTML 599
T+L
Sbjct: 204 GTIL 207
>UniRef50_A5D4M1 Cluster: Zn-dependent alcohol dehydrogenases; n=1;
Pelotomaculum thermopropionicum SI|Rep: Zn-dependent
alcohol dehydrogenases - Pelotomaculum thermopropionicum
SI
Length = 372
Score = 109 bits (261), Expect = 6e-23
Identities = 63/183 (34%), Positives = 103/183 (56%), Gaps = 7/183 (3%)
Frame = +3
Query: 63 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEE-PMIMGH 239
A+++ D+R+ P+PE EVL+++ GIC +D+ K G + E+ P I+GH
Sbjct: 27 AVVHGKGDIRIEPVPVPETGYGEVLVKVRASGICATDI----KTLLGQGLPEKLPAILGH 82
Query: 240 EASGVVAKIGSKVK-NLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNL 416
E +G V ++G V+ +L+ G RVA+ P C C FCK GR++LC A + G
Sbjct: 83 EVAGTVERVGPGVRGDLSPGKRVAVYPIAVCGECFFCKRGRHNLCLREYGLAHG-IDGGF 141
Query: 417 VRYYKHAADFC-----FKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPI 581
+Y + + +LP+H++ E+ A+ EPL+ + A + G + G +LV+GAGP+
Sbjct: 142 AQYVRIPREIVAIGGLVELPEHLSYEQAAMAEPLSCCLAAARAGKLEEGDTMLVVGAGPM 201
Query: 582 GLL 590
GLL
Sbjct: 202 GLL 204
>UniRef50_UPI000038E1A4 Cluster: hypothetical protein Faci_03000847;
n=1; Ferroplasma acidarmanus fer1|Rep: hypothetical
protein Faci_03000847 - Ferroplasma acidarmanus fer1
Length = 333
Score = 108 bits (260), Expect = 9e-23
Identities = 60/174 (34%), Positives = 90/174 (51%)
Frame = +3
Query: 66 LLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEA 245
+L +P L L+ T + EV ++ GICG+D H + G+ H ++ P+I GHE
Sbjct: 5 VLKEPGVLELINTEARKPDTGEVQIKTRACGICGTDFHAYN-GK--HLAVKYPVIPGHEF 61
Query: 246 SGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRY 425
SGV+ IG VK+ GDRV ++P + C CE+CK G+ + C + I G Y
Sbjct: 62 SGVITSIGEGVKSFMPGDRVVVDPNITCGQCEYCKGGKENFC-ENIKTVGINYPGGYGEY 120
Query: 426 YKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGL 587
+K+PD ++ E A++EP+A IHA V G ++ G G IGL
Sbjct: 121 VTVPEKVVYKIPDTMSFEAAAIVEPVACIIHAFDNTHVPLGGSAIISGTGFIGL 174
>UniRef50_Q829Q5 Cluster: Putative zinc-binding dehydrogenase; n=2;
Streptomyces|Rep: Putative zinc-binding dehydrogenase -
Streptomyces avermitilis
Length = 329
Score = 108 bits (260), Expect = 9e-23
Identities = 56/168 (33%), Positives = 89/168 (52%)
Frame = +3
Query: 93 LVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGS 272
+ + P P EV++ + G+CG+D+H Q G F + P++ GHE +G V +G+
Sbjct: 14 VAEVPDPTPGPREVVVEVAACGLCGTDLHILQ----GEFAPKLPIVPGHEFAGEVVGLGT 69
Query: 273 KVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCF 452
+V ++VGDRVA++P + C C +C+TG +LC G RY C
Sbjct: 70 QVTEVSVGDRVAVDPSLYCYECRYCRTGHNNLCERWAAIGVTTA-GGAARYAVAPVANCV 128
Query: 453 KLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLLTM 596
KLP+HV ++ AL+EPL+ + G VLV G+G +GL+ +
Sbjct: 129 KLPEHVRTQDAALIEPLSCAVRGYDVLRSRLGAHVLVYGSGTMGLMML 176
>UniRef50_Q97TZ4 Cluster: Sorbitol dehydrogenase; n=4;
Sulfolobaceae|Rep: Sorbitol dehydrogenase - Sulfolobus
solfataricus
Length = 345
Score = 108 bits (260), Expect = 9e-23
Identities = 62/169 (36%), Positives = 93/169 (55%), Gaps = 5/169 (2%)
Frame = +3
Query: 99 QTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGSKV 278
+ P+P++ + +VL++M G+CG+D+ + CG + +P I+GHE +G++ + S V
Sbjct: 22 ELPLPKLQQGDVLVKMKACGLCGTDI----EKICGQYTASQP-ILGHEPTGIIQE--STV 74
Query: 279 KNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAA-----D 443
L GDRV VPC C +CK G +CP + T G Y++ A
Sbjct: 75 DWLKPGDRVFAHHHVPCYECYYCKKGSPTMCP--YYRKTNLDPGGFSEYFRVPAWNVARG 132
Query: 444 FCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLL 590
KLPD+V+ EEGA +EPLA I A KR + G V ++G GP+GLL
Sbjct: 133 GVLKLPDNVSFEEGAFIEPLATVIRAQKRVAIDNGDTVFIVGIGPMGLL 181
>UniRef50_P39400 Cluster: Uncharacterized zinc-type alcohol
dehydrogenase-like protein yjjN; n=29;
Gammaproteobacteria|Rep: Uncharacterized zinc-type
alcohol dehydrogenase-like protein yjjN - Escherichia
coli (strain K12)
Length = 337
Score = 108 bits (259), Expect = 1e-22
Identities = 60/172 (34%), Positives = 90/172 (52%), Gaps = 1/172 (0%)
Frame = +3
Query: 75 KPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGV 254
+P +L Q IP ++E L+++ VGICG+D+H W Q P ++GHE G
Sbjct: 8 QPKELVWKQREIPIPGDNEALIKIKSVGICGTDIHAWGGNQP---FFSYPRVLGHEICGE 64
Query: 255 VAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKH 434
+ +G + +L G +VA+ P V C+ C CK+GR + C + I G Y
Sbjct: 65 IVGLGKNIADLKNGQQVAVIPYVACQQCPACKSGRTNCC-EKISVIGVHQDGGFSEYL-- 121
Query: 435 AADFCFKLP-DHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGL 587
+ LP D + + AL+EP A+ HA +R ++ G VLV+GAGPIGL
Sbjct: 122 SVPVANILPADGIDPQAAALIEPFAISAHAVRRAAIAPGEQVLVVGAGPIGL 173
>UniRef50_P38105 Cluster: Starvation-sensing protein rspB; n=36;
Proteobacteria|Rep: Starvation-sensing protein rspB -
Escherichia coli (strain K12)
Length = 339
Score = 108 bits (259), Expect = 1e-22
Identities = 59/175 (33%), Positives = 91/175 (52%), Gaps = 1/175 (0%)
Frame = +3
Query: 66 LLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEE-PMIMGHE 242
L+ KPN L +V+ IP S EV +++ GICGSD H ++ GH + P ++GHE
Sbjct: 5 LIEKPNQLAIVEREIPTPSAGEVRVKVKLAGICGSDSHIYR----GHNPFAKYPRVIGHE 60
Query: 243 ASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVR 422
GV+ +G V++ VG+RVA++P V C +C C G+ ++C + G
Sbjct: 61 FFGVIDAVGEGVESARVGERVAVDPVVSCGHCYPCSIGKPNVCTTLAVLGV-HADGGFSE 119
Query: 423 YYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGL 587
Y A +K+P+ V + ++EP + + G + VLV GAGPIGL
Sbjct: 120 YAVVPAKNAWKIPEAVADQYAVMIEPFTIAANVTGHGQPTENDTVLVYGAGPIGL 174
>UniRef50_A5JSX4 Cluster: Zinc-containing alcohol dehydrogenase;
n=1; Bacillus megaterium|Rep: Zinc-containing alcohol
dehydrogenase - Bacillus megaterium
Length = 343
Score = 107 bits (258), Expect = 1e-22
Identities = 57/161 (35%), Positives = 90/161 (55%), Gaps = 1/161 (0%)
Frame = +3
Query: 111 PEISEDEVLLRMDCVGICGSDVH-YWQKGQCGHFVLEEPMIMGHEASGVVAKIGSKVKNL 287
P I + E L+++ GICG+D+ Y+ K H + P+ MGHE SGV+ +I + +
Sbjct: 20 PVIKKGEALVKVSHAGICGTDMMIYFGK----HPRAQAPLTMGHEFSGVIEEIRGETE-F 74
Query: 288 TVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDH 467
++GDRVA+EP + C CE C G++H+C + G ++ + LP+
Sbjct: 75 SLGDRVAVEPTLSCGTCEACVKGQFHVCKQLKLIGIDQ-DGGFAQHVAVPVNRLHLLPEK 133
Query: 468 VTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLL 590
++ E AL EP+AV +H +R + G ++LGAGPIGLL
Sbjct: 134 LSSEHAALAEPVAVAVHTVRRSRLKVGDQAVILGAGPIGLL 174
>UniRef50_A0JXR0 Cluster: Alcohol dehydrogenase, zinc-binding domain
protein; n=5; Actinobacteria (class)|Rep: Alcohol
dehydrogenase, zinc-binding domain protein -
Arthrobacter sp. (strain FB24)
Length = 355
Score = 107 bits (257), Expect = 2e-22
Identities = 60/175 (34%), Positives = 81/175 (46%), Gaps = 4/175 (2%)
Frame = +3
Query: 84 DLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAK 263
DLR+ P+P DE ++ + GICGSD+HYW G G +L PM++GHE G V
Sbjct: 21 DLRIEDVPVPPPGPDEAVVEVAFGGICGSDLHYWLHGAAGESILRVPMVLGHEIVGTVLH 80
Query: 264 IGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCAT----PPVHGNLVRYYK 431
+ G VA+ P P R +L P + + P G RY
Sbjct: 81 AAADGTGPEAGTPVAVHPATPGPGAARYPEDRPNLSPGCTYLGSAARYPHTDGAFSRYAT 140
Query: 432 HAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLLTM 596
A LPD +++ AL EP +V HA R G G LV+G+GPIG L +
Sbjct: 141 LPARMLRPLPDGLSLRTAALAEPASVAWHAVARAGDVTGKTALVIGSGPIGALAV 195
>UniRef50_Q9RKG0 Cluster: Putative dehydrogenase; n=1; Streptomyces
coelicolor|Rep: Putative dehydrogenase - Streptomyces
coelicolor
Length = 344
Score = 107 bits (256), Expect = 3e-22
Identities = 65/186 (34%), Positives = 97/186 (52%), Gaps = 2/186 (1%)
Frame = +3
Query: 48 TDNLTALLYKP-NDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEP 224
T ++A+++ ND+R+ + P+PE+ L+R+ C GICG+D+ G+ H +
Sbjct: 2 TGGMSAVVWAGVNDVRVEEVPMPEVPPGWALVRVACTGICGTDLGIVH-GK--HPRARQG 58
Query: 225 MIMGHEASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDM-IFCATPP 401
+I+GHE SG V G V EP + C+ C C+ G H+C + +F P
Sbjct: 59 LILGHEISGWVEVTAPG--GPPEGALVVAEPLISCKDCRACREGHSHVCARLGLFGIDAP 116
Query: 402 VHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPI 581
G ++ ++P V + AL EPLAV +HA R G+ AG VV V GAGPI
Sbjct: 117 --GGAAQFVALPTSTLHQVPSRVEPTQAALTEPLAVAVHAVSRSGMEAGDVVAVFGAGPI 174
Query: 582 GLLTML 599
G+LT L
Sbjct: 175 GILTAL 180
>UniRef50_Q5BBC2 Cluster: Putative uncharacterized protein; n=1;
Emericella nidulans|Rep: Putative uncharacterized
protein - Emericella nidulans (Aspergillus nidulans)
Length = 353
Score = 107 bits (256), Expect = 3e-22
Identities = 63/175 (36%), Positives = 86/175 (49%), Gaps = 7/175 (4%)
Frame = +3
Query: 84 DLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCG-----HFVL--EEPMIMGHE 242
D+R+ Q P +E +V +R VGICGSD+H + G H + + P+ +GHE
Sbjct: 11 DIRVDQIDEPSCAEGQVKIRPAFVGICGSDLHEYLSGPIAIPTTPHPLTGAQLPVTLGHE 70
Query: 243 ASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVR 422
SG + ++G V VGDRVA+ P + C C GR + C + F G L
Sbjct: 71 FSGTIEEVGQGVTGFKVGDRVAVRPNLSDGTCASCVYGRPNCCRSLGFIGFSSNSGGLSD 130
Query: 423 YYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGL 587
Y A LP+ V ++ GAL+EPL V HA R LV+G GPIGL
Sbjct: 131 YVTVPAKHAILLPESVPLDLGALVEPLTVAWHAVARSPHETARTALVVGGGPIGL 185
>UniRef50_A2R6Z1 Cluster: Catalytic activity: L-iditol + NAD(+) <=>
L-sorbose + NADH; n=1; Aspergillus niger|Rep: Catalytic
activity: L-iditol + NAD(+) <=> L-sorbose + NADH -
Aspergillus niger
Length = 159
Score = 107 bits (256), Expect = 3e-22
Identities = 42/89 (47%), Positives = 61/89 (68%), Gaps = 1/89 (1%)
Frame = +3
Query: 108 IPEISED-EVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGSKVKN 284
IP I D +VL+R+ G+CGSD+HYWQ G+ G + + +P+I+ HE+SGV+ G +
Sbjct: 27 IPTIESDRDVLVRVVATGLCGSDIHYWQHGKLGEYEVTQPLILAHESSGVIVATGGNFQG 86
Query: 285 LTVGDRVAIEPGVPCRYCEFCKTGRYHLC 371
L + DRVA+EP PC C +C++GRY LC
Sbjct: 87 LKINDRVALEPRNPCNVCPYCRSGRYKLC 115
>UniRef50_UPI00015970BD Cluster: GutB1; n=1; Bacillus
amyloliquefaciens FZB42|Rep: GutB1 - Bacillus
amyloliquefaciens FZB42
Length = 348
Score = 106 bits (255), Expect = 3e-22
Identities = 62/184 (33%), Positives = 96/184 (52%), Gaps = 3/184 (1%)
Frame = +3
Query: 57 LTALLYKPND-LRLVQTPIPEISE-DEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMI 230
+ AL++ PND L + P+I + ++V +++ GICG+D++ + G MI
Sbjct: 1 MKALVWTPNDKLEYQEVDEPQIRKSNDVKVKIFGTGICGTDLNVLK----GKMNATHHMI 56
Query: 231 MGHEASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDM-IFCATPPVH 407
MGHE+ G V +IG V N+ VGDRV I+P C C +C+ G C + H
Sbjct: 57 MGHESVGAVVEIGPDVTNVKVGDRVVIDPTQFCGKCHYCRRGLTCYCETFEDWQLGIGAH 116
Query: 408 GNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGL 587
G YY F +++PD + E L+EPL+ ++ + + VLVLG+GPIGL
Sbjct: 117 GTFAEYYVGEDRFMYRIPDSMEWERATLVEPLSCVLNVVDKASIQPEDSVLVLGSGPIGL 176
Query: 588 LTML 599
L +
Sbjct: 177 LVQM 180
>UniRef50_Q1ARQ8 Cluster: Alcohol dehydrogenase GroES-like protein
precursor; n=1; Rubrobacter xylanophilus DSM 9941|Rep:
Alcohol dehydrogenase GroES-like protein precursor -
Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 341
Score = 106 bits (255), Expect = 3e-22
Identities = 62/176 (35%), Positives = 91/176 (51%), Gaps = 3/176 (1%)
Frame = +3
Query: 78 PNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVV 257
P ++ + + P PE V+LR GICGS+V + G+ G+ P++MGHE SG V
Sbjct: 9 PREMAVEEIPEPEAGPGAVVLRTGAAGICGSEVEGYL-GRMGNRT--PPLVMGHEFSGTV 65
Query: 258 AKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVH--GNLVRYYK 431
+G V VG RVA+ P + C C C++G ++CP+ A +H G Y +
Sbjct: 66 VAVGEGVDEAWVGRRVAVNPLISCGECRLCRSGHENICPER---ALIGIHRPGAFAEYVE 122
Query: 432 HAADFCFKLPDHVTMEEGALLEPLAVGIHACKRG-GVSAGHVVLVLGAGPIGLLTM 596
A LP+ V + AL EPLA G+HA G + +V+GAG IGL+ +
Sbjct: 123 VPAGSLHALPEGVDLRSAALAEPLANGVHAAGLGLERGPAELAVVVGAGTIGLMCL 178
>UniRef50_O58389 Cluster: Probable L-threonine 3-dehydrogenase; n=7;
cellular organisms|Rep: Probable L-threonine
3-dehydrogenase - Pyrococcus horikoshii
Length = 348
Score = 106 bits (255), Expect = 3e-22
Identities = 56/166 (33%), Positives = 86/166 (51%)
Frame = +3
Query: 93 LVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGS 272
LV+ +P+ EVL+++ ICG+D+H ++ + ++ P IMGHE +G V +IG
Sbjct: 19 LVEVDVPKPGPGEVLIKVLATSICGTDLHIYEWNEWAQSRIKPPQIMGHEVAGEVVEIGP 78
Query: 273 KVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCF 452
V+ + VGD V++E + C C C+ G+YH+C + G Y A +
Sbjct: 79 GVEGIEVGDYVSVETHIVCGKCYACRRGQYHVCQNTKIFGV-DTDGVFAEYAVVPAQNIW 137
Query: 453 KLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLL 590
K P + E L EPL + G +S G VL+ GAGP+GLL
Sbjct: 138 KNPKSIPPEYATLQEPLGNAVDTVLAGPIS-GKSVLITGAGPLGLL 182
>UniRef50_Q9RTU4 Cluster: L-threonine 3-dehydrogenase; n=178;
Bacteria|Rep: L-threonine 3-dehydrogenase - Deinococcus
radiodurans
Length = 348
Score = 106 bits (255), Expect = 3e-22
Identities = 56/166 (33%), Positives = 88/166 (53%)
Frame = +3
Query: 93 LVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGS 272
+++T +P +++L+R+ ICG+DVH ++ + PM++GHE GVVA +GS
Sbjct: 15 MIETEVPTPGPNDLLIRIRKGSICGTDVHIYKWDDWASQTVPVPMVVGHEYVGVVAGMGS 74
Query: 273 KVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCF 452
+V+ +GDRV+ E V C +C C+ GR HLC + G+ Y A F
Sbjct: 75 EVRGFEIGDRVSGEGHVTCGHCRNCRAGRRHLCRNTQGVGVNR-PGSFAEYLVLPAFNAF 133
Query: 453 KLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLL 590
KLPD + + A+ +P +H + G VL+ GAGPIG +
Sbjct: 134 KLPDDIPDDVAAIFDPFGNAVHTALSFDL-VGEDVLITGAGPIGCM 178
>UniRef50_Q987C5 Cluster: Alcohol dehydrogenase; n=4;
Rhizobiales|Rep: Alcohol dehydrogenase - Rhizobium loti
(Mesorhizobium loti)
Length = 341
Score = 106 bits (254), Expect = 5e-22
Identities = 67/180 (37%), Positives = 88/180 (48%), Gaps = 1/180 (0%)
Frame = +3
Query: 63 ALLYKPNDLRLVQTPIPEISEDE-VLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGH 239
A LY P DLR+ P I + V LR+D GICGSD+H ++ GQ ++ P GH
Sbjct: 4 ARLYGPGDLRVEDVAPPGIPDPGWVKLRVDAAGICGSDLHNFRTGQ---WISRSPSTAGH 60
Query: 240 EASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLV 419
E +G V +G V + VGDRV + C C C+ GR HLC + F G
Sbjct: 61 ELTGTVTALGEGVDTVAVGDRVVADSRFWCEECVQCRAGRRHLCASLGFVG-EVCDGGFA 119
Query: 420 RYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLLTML 599
A + + A+ EPLAV +HA +R +AG VLV+G GPIG L L
Sbjct: 120 EQVVLPARLLHVVDAALDERVAAMAEPLAVALHAVRRLPKTAGS-VLVVGCGPIGGLAAL 178
>UniRef50_Q44P31 Cluster: Zinc-containing alcohol dehydrogenase
superfamily; n=3; Chlorobiaceae|Rep: Zinc-containing
alcohol dehydrogenase superfamily - Chlorobium limicola
DSM 245
Length = 421
Score = 106 bits (254), Expect = 5e-22
Identities = 63/178 (35%), Positives = 83/178 (46%)
Frame = +3
Query: 66 LLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEA 245
+L +P L L + PE EDE L+R+ C +C +D WQ G H L P ++GHE
Sbjct: 106 VLKEPRSLGLCERNDPETGEDEALVRVVCCSVCRTDAKMWQSG---HRDLVMPRVLGHEI 162
Query: 246 SGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRY 425
SG + +RVA+ PG+ C C FC GR +LC M G Y
Sbjct: 163 SGYLDN-----------ERVAVWPGISCGSCAFCLAGRENLCASMQILGFHH-DGGFAEY 210
Query: 426 YKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLLTML 599
+PD + ME AL EPL +H R GV +G VL+ GAG +GL L
Sbjct: 211 VAVRRTSLLSVPDTLPMELAALAEPLGCALHGLDRAGVRSGERVLIYGAGSLGLFLAL 268
>UniRef50_Q3W5D6 Cluster: Zinc-containing alcohol dehydrogenase
superfamily; n=1; Frankia sp. EAN1pec|Rep:
Zinc-containing alcohol dehydrogenase superfamily -
Frankia sp. EAN1pec
Length = 350
Score = 106 bits (254), Expect = 5e-22
Identities = 61/184 (33%), Positives = 96/184 (52%), Gaps = 7/184 (3%)
Frame = +3
Query: 57 LTALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPM--- 227
+ A L+ P DLR+ + PE + EV + + G+CG+D+ G + P+
Sbjct: 2 IAARLHGPGDLRVEEVDEPEAAAGEVKIAVAHNGLCGTDLTEIFSGPRACTTVPHPLTGG 61
Query: 228 ----IMGHEASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCAT 395
I+GHE +GVVA +G+ V ++ V +RV++EP C C+ C+ LC ++
Sbjct: 62 VLPQIVGHEFAGVVAAVGAGVTDVAVSERVSVEPLYSCGDCDRCQASLPELCRQVMTHGI 121
Query: 396 PPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAG 575
G L ++ +LP +++ EGAL+EP+AV + R GV AG LV GAG
Sbjct: 122 CSNGGGLAQFTTVPRAMVHRLPASMSLAEGALVEPMAVAFNGVLRSGVEAGGSALVFGAG 181
Query: 576 PIGL 587
PIG+
Sbjct: 182 PIGM 185
>UniRef50_A3Q0B4 Cluster: Alcohol dehydrogenase GroES domain
protein; n=4; Mycobacterium|Rep: Alcohol dehydrogenase
GroES domain protein - Mycobacterium sp. (strain JLS)
Length = 347
Score = 106 bits (254), Expect = 5e-22
Identities = 63/164 (38%), Positives = 86/164 (52%), Gaps = 7/164 (4%)
Frame = +3
Query: 129 EVLLRMDCVGICGSDVHYWQKGQCG-HFVLEEPMIMGHEASGVVAKIGSKVKNLTVGDRV 305
EV + VGICGSD+H CG H ++ P GHEA GVV +G+ V +G RV
Sbjct: 32 EVRVGTSLVGICGSDLH----AACGRHPFIDLPYRPGHEAVGVVDAVGAGVDESWLGTRV 87
Query: 306 AIEPGVPCRYCEFCKTGRYHLCPDMIF--CATPPVHGNLVRYYKHAADFCFKLPDHVTME 479
IEP + C +C C+ GRY++C +++ C T G L + D LPD +
Sbjct: 88 TIEPNLACGHCTQCRAGRYNICRELLVFGCQTA---GALADSFTIPVDRVVALPDELDDR 144
Query: 480 EGALLEPLAVGIHACKRGGVSAG----HVVLVLGAGPIGLLTML 599
L+EPLA +H +R G V+V+GAGPIGL T+L
Sbjct: 145 HAILIEPLATPVHTVRRAAGLVGDLRDRAVVVIGAGPIGLFTLL 188
>UniRef50_A0LL41 Cluster: Alcohol dehydrogenase GroES domain
protein; n=1; Syntrophobacter fumaroxidans MPOB|Rep:
Alcohol dehydrogenase GroES domain protein -
Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB)
Length = 338
Score = 106 bits (254), Expect = 5e-22
Identities = 58/171 (33%), Positives = 85/171 (49%), Gaps = 1/171 (0%)
Frame = +3
Query: 81 NDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVA 260
ND+R+ + P E+LL++ GICGSDV W + P++ GHE V
Sbjct: 10 NDIRIEEVATPRPGPKEMLLKVASCGICGSDVVEWYRKP------RAPLVQGHEIGAEVV 63
Query: 261 KIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAA 440
++GS V VG+RV P VPC C +C+ G Y C + I P + +
Sbjct: 64 EVGSSVTGFKVGERVFAVPKVPCMECHYCRNGHYPQCAE-IKVRLPGGFAEYILVPEILV 122
Query: 441 D-FCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLL 590
+ + LPD +T ++ +EPLA + A + G+ AG V+VLG G GLL
Sbjct: 123 EKGTYHLPDTITYDQSTFIEPLACVVRAQRLAGIRAGQTVVVLGCGMSGLL 173
>UniRef50_Q6BC32 Cluster: Glycerol dehydrogenase; n=3;
Saccharomycetales|Rep: Glycerol dehydrogenase - Pichia
angusta (Yeast) (Hansenula polymorpha)
Length = 380
Score = 106 bits (254), Expect = 5e-22
Identities = 72/205 (35%), Positives = 100/205 (48%), Gaps = 27/205 (13%)
Frame = +3
Query: 66 LLYKPNDLRLVQT-PIPEISE-DEVLLRMDCVGICGSDV-HYWQKGQCGHFV-------- 212
L Y ND+R +T P PEI ++V +++ GICG+D+ + G F
Sbjct: 5 LYYGTNDIRYSETVPEPEIKNPNDVKIKVSYCGICGTDLKEFTYSGGPVFFPKQGTKDKI 64
Query: 213 --LEEPMIMGHEASGVVAKIGSKVKNLTVGDRVAIEPGVPC----RY----------CEF 344
E P+ GHE SG V ++GS V ++ GDRVA+E C RY C
Sbjct: 65 SGYELPLCPGHEFSGTVVEVGSGVTSVKPGDRVAVEATSHCSDRSRYKDTVAQDLGLCMA 124
Query: 345 CKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHAC 524
C++G + C + FC G Y + D KLPD + + GAL+EP++V HA
Sbjct: 125 CQSGSPNCCASLSFCGLGGASGGFAEYVVYGEDHMVKLPDSIPDDIGALVEPISVAWHAV 184
Query: 525 KRGGVSAGHVVLVLGAGPIGLLTML 599
+R G LVLG GPIGL T+L
Sbjct: 185 ERARFQPGQTALVLGGGPIGLATIL 209
>UniRef50_Q46NN2 Cluster: Zinc-containing alcohol dehydrogenase
superfamily; n=1; Ralstonia eutropha JMP134|Rep:
Zinc-containing alcohol dehydrogenase superfamily -
Ralstonia eutropha (strain JMP134) (Alcaligenes
eutrophus)
Length = 367
Score = 105 bits (253), Expect = 6e-22
Identities = 67/195 (34%), Positives = 97/195 (49%), Gaps = 12/195 (6%)
Frame = +3
Query: 42 MATDNLTALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEE 221
M + L +L P +L+ + PIPEI +D+ +LR++ G+CG+D W G +
Sbjct: 1 MTRNALALVLESPKNLQAREFPIPEIGDDDAVLRVEACGLCGTDYEQW-LGHMKDWGGGM 59
Query: 222 PMIMGHEASGVVAKIG---SKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLC-PDMIF- 386
P+I GHE G + +IG +K N+ GDRVAIEP +PC +CE C G Y C D+ +
Sbjct: 60 PIIPGHEIMGFIERIGTLAAKRWNVREGDRVAIEPIIPCGHCEDCVRGAYTRCQSDLGYG 119
Query: 387 -----CATPPVHGNLVRY-YKHAADFCFKLPDHVTMEEGALLEPLAVGIH-ACKRGGVSA 545
P + G + Y H KLP + E L+ PL+ I + GG
Sbjct: 120 LYQSTAVAPHLWGGYATHVYLHPRTMVHKLPTDLPTEVMTLVNPLSNAIRWVYEAGGAGL 179
Query: 546 GHVVLVLGAGPIGLL 590
G V++ G G GLL
Sbjct: 180 GKTVVIAGPGQRGLL 194
>UniRef50_Q5B6Y0 Cluster: Putative uncharacterized protein; n=1;
Emericella nidulans|Rep: Putative uncharacterized
protein - Emericella nidulans (Aspergillus nidulans)
Length = 351
Score = 105 bits (253), Expect = 6e-22
Identities = 59/182 (32%), Positives = 95/182 (52%), Gaps = 12/182 (6%)
Frame = +3
Query: 87 LRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGV---V 257
L + P+ +EVL+++ GICGSD H W + +I+GHE++G+ +
Sbjct: 15 LAIQDRPVTPPGPNEVLVQVISTGICGSDTHNWNNPN-----VSRELILGHESAGLRGLI 69
Query: 258 AKIGSKVKNLTVGDRVAIEPGVPC--RYCE------FCKTGRYHLCPDMIFCATPPVHGN 413
+I S+VK+ VG R+A+EPG C R C FC G + C ++ +C P G
Sbjct: 70 VEIDSEVKDRHVGQRMAVEPGFACATRKCPDNQEDAFCLRGNPNTCANLKYCGLDPTDGT 129
Query: 414 LVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSA-GHVVLVLGAGPIGLL 590
L +Y+ A +P+ ++ EE ++PLA+ + +R +SA VV G GP+GLL
Sbjct: 130 LQQYFTCKAHMAIPIPEEISWEEAGAIQPLAIAVQLARRAALSATAKVVGDGGCGPLGLL 189
Query: 591 TM 596
+
Sbjct: 190 VI 191
>UniRef50_Q62AB8 Cluster: Oxidoreductase, zinc-binding dehydrogenase
family; n=28; Bacteria|Rep: Oxidoreductase, zinc-binding
dehydrogenase family - Burkholderia mallei (Pseudomonas
mallei)
Length = 378
Score = 105 bits (252), Expect = 8e-22
Identities = 63/181 (34%), Positives = 93/181 (51%), Gaps = 11/181 (6%)
Frame = +3
Query: 78 PNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVH-------YWQKGQCGHFVLEEPMIMG 236
P D RL Q P+P+ DE+L +++ VGIC D+ +W +V + PMI G
Sbjct: 33 PQDYRLEQVPVPKPGPDEILTQVERVGICMGDIKTFRGAPSFWGDAVQPRYV-KPPMIPG 91
Query: 237 HEASGVVAKIG--SKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDM-IFCATPPVH 407
HE V +G ++ + + VGDRV E VPC C FC G+Y +C ++ VH
Sbjct: 92 HEFVCRVVALGPGAERRGVKVGDRVISEQIVPCWSCRFCGHGQYWMCQKHDLYGFQNNVH 151
Query: 408 GNLVRYYKHAAD-FCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIG 584
G + Y + ++PD + +E L+EPL+ +HA R V VV+V GAG +G
Sbjct: 152 GAMAEYMIFTKEAIVHRVPDSIPTDEAILIEPLSCSLHAADRANVGFDDVVVVAGAGTLG 211
Query: 585 L 587
L
Sbjct: 212 L 212
>UniRef50_Q59715 Cluster: Benzyl alcohol dehydrogenase II; n=5;
Pseudomonas|Rep: Benzyl alcohol dehydrogenase II -
Pseudomonas putida
Length = 348
Score = 105 bits (252), Expect = 8e-22
Identities = 56/174 (32%), Positives = 91/174 (52%), Gaps = 1/174 (0%)
Frame = +3
Query: 78 PNDLRLVQTPIP-EISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGV 254
P L + P E +VL++++ GICG+D+ ++ G+ ++ P I+GHE SGV
Sbjct: 11 PGGLSVDDVAAPKEAHSTDVLVKVEAAGICGTDLLIYKWGEFAKR-MKLPTILGHEVSGV 69
Query: 255 VAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKH 434
+ ++GS VK L G RV++E +PC C C+ G H+CP + G +
Sbjct: 70 IEQVGSDVKGLRPGMRVSLESHLPCGTCYTCRRGWAHVCPKTRYPGV-DFDGGFASFVVV 128
Query: 435 AADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLLTM 596
C+ +P + + A++EP + +HA G +G VLV G GPIGL+ +
Sbjct: 129 PESVCWPVPCGIPPLQAAMMEPFGLAVHASLEGSGVSGLNVLVSGCGPIGLMNI 182
>UniRef50_Q72U55 Cluster: Zinc binding dehydrogenase; n=4;
Leptospira|Rep: Zinc binding dehydrogenase - Leptospira
interrogans serogroup Icterohaemorrhagiae
serovarcopenhageni
Length = 348
Score = 105 bits (251), Expect = 1e-21
Identities = 54/172 (31%), Positives = 91/172 (52%), Gaps = 5/172 (2%)
Frame = +3
Query: 87 LRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKG--QCGHFVLEEPMIMGHEASGVVA 260
L + +P++ ++V +R+ GICGSDVH G +C HF P + GHE+SG++
Sbjct: 18 LEIRDVSVPQLRAEQVKVRIKACGICGSDVHLVVHGTLKCKHF----PRVPGHESSGIIE 73
Query: 261 KIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDM-IFCATPPVHGNLVRYYKHA 437
++G V+ GDRV I G C C +CK G+ +LC D+ +F G+ +
Sbjct: 74 EVGENVRRFRKGDRVVIAAGTSCGVCSYCKEGKENLCKDLGVFGFDR--DGSFAEFNIVE 131
Query: 438 ADFCFKLPDHVTMEEGALL-EPLAVGIHACK-RGGVSAGHVVLVLGAGPIGL 587
+ + LPD + ++GA+L + ++ HA + RG + V + G G +G+
Sbjct: 132 ERYLYSLPDEIPFDQGAILADAVSTPYHAIRYRGNIQESDTVAIFGCGGLGI 183
>UniRef50_Q12E06 Cluster: Alcohol dehydrogenase GroES-like; n=2;
Bacteria|Rep: Alcohol dehydrogenase GroES-like -
Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 346
Score = 105 bits (251), Expect = 1e-21
Identities = 61/181 (33%), Positives = 91/181 (50%), Gaps = 5/181 (2%)
Frame = +3
Query: 63 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 242
A+L P L+L PE + E++LR+ +CG+D+ + + P ++GHE
Sbjct: 4 AVLRAPKVLQLSDIATPEAAPGELVLRVRAAMVCGTDLRILTGRKTKG--VRFPSVIGHE 61
Query: 243 ASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVR 422
+G V ++G V GDRV ++P +PCR C +CKTG ++C G
Sbjct: 62 FAGEVVQVGDGVTQFKTGDRVCMDPVIPCRACAYCKTGHENVCLHRQAMGY-EFDGAFAE 120
Query: 423 YYK-----HAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGL 587
Y + A F +P ++ E AL EPLA I+ + GV G V+VLGAGPIGL
Sbjct: 121 YIRIPAIALTAGNVFMMPAQMSFESAALAEPLACCINGQRNAGVQVGDTVVVLGAGPIGL 180
Query: 588 L 590
+
Sbjct: 181 M 181
>UniRef50_A3U1C0 Cluster: Threonine 3-dehydrogenase; n=1; Oceanicola
batsensis HTCC2597|Rep: Threonine 3-dehydrogenase -
Oceanicola batsensis HTCC2597
Length = 349
Score = 105 bits (251), Expect = 1e-21
Identities = 70/172 (40%), Positives = 87/172 (50%), Gaps = 6/172 (3%)
Frame = +3
Query: 87 LRLVQTPIPEISE-DEVLLRMDCVGICGSDVHY--WQKGQCGHFVLEE-PMIMGHEASGV 254
L L P P E EV +R++ VGICGSD+H W G F+L P+ +GHE +G+
Sbjct: 13 LSLDDCPAPGAPEAGEVTVRVEAVGICGSDLHVADWSGGY--DFMLPHLPLTLGHEFAGI 70
Query: 255 VAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVH--GNLVRYY 428
+ G V +T GDRV I P PC C C GR C + AT ++ G
Sbjct: 71 IEATGPGVARVTPGDRVTIWPSSPCDTCPECTAGRRRNCRNK---ATLGLYRDGAFAPLV 127
Query: 429 KHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIG 584
A F +PD ++ E AL EPL VG A K G VS G VLVLG G IG
Sbjct: 128 TARAQGAFTIPDALSFEIAALTEPLCVGRRAVKTGEVSPGDRVLVLGPGTIG 179
>UniRef50_Q3ZWK2 Cluster: Alcohol dehydrogenase, zinc-containing;
n=3; Dehalococcoides|Rep: Alcohol dehydrogenase,
zinc-containing - Dehalococcoides sp. (strain CBDB1)
Length = 343
Score = 104 bits (250), Expect = 1e-21
Identities = 69/179 (38%), Positives = 91/179 (50%), Gaps = 4/179 (2%)
Frame = +3
Query: 66 LLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEA 245
LL KP +LRL + P + VLL++ C ICG+DV +++G H LE P I+GHE
Sbjct: 5 LLEKPGELRLAEVVTPYCPKGGVLLKVLCCAICGTDVKMFRRG---HRDLEYPRILGHEI 61
Query: 246 SGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRY 425
+ V G + G RV + PG+ C C C GR +LC + G L Y
Sbjct: 62 AAEVVCSGHP--DFEAGCRVQVYPGIACGVCPLCLQGRENLCRKVKIIGFN-YDGGLAEY 118
Query: 426 YKHAADFCFK----LPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLL 590
+ +P+HV+ EE +L EPLA IHA V G VLVLGAGP+GLL
Sbjct: 119 MALPPESLPVGLNIIPEHVSDEEASLAEPLASCIHAQSVCRVGDGDRVLVLGAGPLGLL 177
>UniRef50_A5WI29 Cluster: Alcohol dehydrogenase, zinc-binding domain
protein; n=18; Bacteria|Rep: Alcohol dehydrogenase,
zinc-binding domain protein - Psychrobacter sp. PRwf-1
Length = 354
Score = 104 bits (249), Expect = 2e-21
Identities = 63/185 (34%), Positives = 90/185 (48%), Gaps = 9/185 (4%)
Frame = +3
Query: 63 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQ-----CGHF--VLEE 221
A Y D+R+ P P + V +++ GICG+D+H + +G CGH + E
Sbjct: 4 ARFYDKGDIRIEDIPEPTVKPGTVGIKVAWCGICGTDLHEFMEGPIFIPPCGHPHPISGE 63
Query: 222 --PMIMGHEASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCAT 395
P+ MGHE SGVV +G V ++ +G V +EP + YHL DM F
Sbjct: 64 SAPVTMGHEFSGVVYAVGEGVNDIEIGQHVVVEPYIVADDVPTGPGDNYHLSKDMNFIGL 123
Query: 396 PPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAG 575
G L + + + + +++ AL+EPLAVG HA R G G + LV G G
Sbjct: 124 GGRGGGLSEKIAVERRWVHPISNKIPLDQAALIEPLAVGYHAFIRSGAQKGDIALVGGGG 183
Query: 576 PIGLL 590
PIGLL
Sbjct: 184 PIGLL 188
>UniRef50_Q9UAT1 Cluster: Putative uncharacterized protein; n=1;
Caenorhabditis elegans|Rep: Putative uncharacterized
protein - Caenorhabditis elegans
Length = 326
Score = 104 bits (249), Expect = 2e-21
Identities = 64/165 (38%), Positives = 88/165 (53%), Gaps = 2/165 (1%)
Frame = +3
Query: 87 LRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKI 266
L + Q PIP+ +EDE+L++M+ GIC SDVH W G H+V + PMI GHE +G V +
Sbjct: 22 LEIKQLPIPQPNEDELLVKMEYSGICHSDVHTWL-GDF-HYVSKCPMIGGHEGAGSVISV 79
Query: 267 GSKVKNLTVGDRVAIE-PGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAAD 443
GSKVKN +GD+V I+ C CE+C+TG LCP ++ +G Y
Sbjct: 80 GSKVKNWQIGDKVGIKLVQGNCLNCEYCQTGHEPLCPH-VWNIGVQKYGTFQEYATIRDV 138
Query: 444 FCFKLPDHVTMEEGA-LLEPLAVGIHACKRGGVSAGHVVLVLGAG 575
K+P + M A +L A K V +G +V V GAG
Sbjct: 139 DAIKIPKSMNMAAAAPVLCGGVTAYKALKESEVKSGQIVAVTGAG 183
>UniRef50_Q0UBF8 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 288
Score = 103 bits (248), Expect = 2e-21
Identities = 63/179 (35%), Positives = 95/179 (53%), Gaps = 1/179 (0%)
Frame = +3
Query: 57 LTALLYKPND-LRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIM 233
+ AL Y + +VQ +P I +D+VL+++ G+CG+D+HY + G F+ + P+I
Sbjct: 22 MKALQYSEAEKFAVVQIDVPSIGDDDVLVKISACGVCGTDLHYHK----GEFLAKWPLIP 77
Query: 234 GHEASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGN 413
GHEA+G +A IG+ VKN++VGDRVA +P PC C +H F P G
Sbjct: 78 GHEAAGTIAAIGANVKNVSVGDRVAADPMQPCLTC-------FHS-----FGGNVP--GG 123
Query: 414 LVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLL 590
Y ++ A + D +E L+EP A H +R + G VL+ G GP G+L
Sbjct: 124 FAEYCRYPARQVHPIGDLPDLE-AILVEPAACATHGIERMQIEVGSRVLLFGCGPTGIL 181
>UniRef50_Q0RW76 Cluster: Probable Zn-containing alcohol
dehydrogenase; n=1; Rhodococcus sp. RHA1|Rep: Probable
Zn-containing alcohol dehydrogenase - Rhodococcus sp.
(strain RHA1)
Length = 353
Score = 103 bits (247), Expect = 3e-21
Identities = 61/187 (32%), Positives = 90/187 (48%), Gaps = 6/187 (3%)
Frame = +3
Query: 57 LTALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQC----GHFVLEE- 221
L LY+ +D RL + P PE+ V +++ GICGSD+ ++ + +++E
Sbjct: 2 LALRLYREHDARLEEVPEPELRPGAVKVKVAWAGICGSDLSLFETAPVPLDYSNPIMQET 61
Query: 222 -PMIMGHEASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATP 398
P +GHE SG V ++ V + VGD VA+ P C C+ G ++C + F
Sbjct: 62 GPHTLGHEFSGYVTEVAEGVTTVQVGDLVAVRPNFADGTCPSCQAGHPNMCDNFAFIGIN 121
Query: 399 PVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGP 578
G AD + LP + AL+EPL V HA K + LV+GAGP
Sbjct: 122 GWGGGFSESVVVPADHAYVLPPGFNAQIAALIEPLTVAWHAVKLAEIPKDGTALVVGAGP 181
Query: 579 IGLLTML 599
IGL T+L
Sbjct: 182 IGLSTVL 188
>UniRef50_Q5K658 Cluster: Sorbitol dehydrogenase; n=2; Dikarya|Rep:
Sorbitol dehydrogenase - Paracoccidioides brasiliensis
Length = 124
Score = 103 bits (247), Expect = 3e-21
Identities = 46/110 (41%), Positives = 71/110 (64%), Gaps = 3/110 (2%)
Frame = +3
Query: 66 LLYKPNDLRLVQ--TPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGH 239
+L+ P DLRL TP P+ E ++ +R G+CGSD+HY+ G+ G F+++ P+ +GH
Sbjct: 14 VLHAPRDLRLESRLTPAPKHGELQIAIR--ATGLCGSDLHYYNHGRNGDFIVQSPLCLGH 71
Query: 240 EASGVVAKIGSKVKN-LTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIF 386
E+SG++ IG V + +GDRVA+E G+PC C C GRY++C + F
Sbjct: 72 ESSGIITAIGPDVADTFHIGDRVALEVGLPCHSCPLCLQGRYNICRKLRF 121
>UniRef50_Q8R7K0 Cluster: L-threonine 3-dehydrogenase; n=3; cellular
organisms|Rep: L-threonine 3-dehydrogenase -
Thermoanaerobacter tengcongensis
Length = 347
Score = 103 bits (247), Expect = 3e-21
Identities = 55/175 (31%), Positives = 86/175 (49%)
Frame = +3
Query: 72 YKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASG 251
Y +V+ IP+I DEVL+++ ICG+DVH + + ++ P MGHE G
Sbjct: 12 YHKEGADIVKKEIPKIGPDEVLIKVKATSICGTDVHIYVWNEWAKSRIKPPKTMGHEFVG 71
Query: 252 VVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYK 431
V +IG V ++ VGD V+ E + C C C+TG H+C + + G Y K
Sbjct: 72 EVVEIGENVTSVKVGDLVSAETHIVCGKCRACRTGNAHICENTLILGV-DTDGAFAEYIK 130
Query: 432 HAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLLTM 596
+ ++ +E ++ EPL +H G V G V V+G GPIG++ +
Sbjct: 131 VPESNVWINDKNIPLEILSIQEPLGNAVHTVFSGDV-VGKSVAVIGCGPIGMMAI 184
>UniRef50_Q3B3S5 Cluster: Alcohol dehydrogenase, zinc-containing;
n=1; Pelodictyon luteolum DSM 273|Rep: Alcohol
dehydrogenase, zinc-containing - Pelodictyon luteolum
(strain DSM 273) (Chlorobium luteolum (strain DSM273))
Length = 323
Score = 103 bits (246), Expect = 4e-21
Identities = 63/178 (35%), Positives = 85/178 (47%)
Frame = +3
Query: 66 LLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEA 245
LL P L ++ PIP E EVLLR+ IC +D W G H L P ++GHE
Sbjct: 5 LLCGPKSLSILDRPIPIPGEGEVLLRVRAAAICRTDAKMWSSG---HRDLRLPRVLGHEV 61
Query: 246 SGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRY 425
SG + G+ G A+ PG C C C++GR +LCPDM G +
Sbjct: 62 SGTIE--GNP------GQLYALWPGQACGSCMACRSGRQNLCPDMRITGFHR-DGGFAEF 112
Query: 426 YKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLLTML 599
++P+ V L EPLA +H ++GGVS+ VL+ GAG +GLL L
Sbjct: 113 LTAPRSSLLEVPEGVGPVMATLAEPLACAVHGVRQGGVSSRERVLIYGAGTLGLLVAL 170
>UniRef50_Q1AZ51 Cluster: Alcohol dehydrogenase GroES-like protein;
n=2; Bacteria|Rep: Alcohol dehydrogenase GroES-like
protein - Rubrobacter xylanophilus (strain DSM 9941 /
NBRC 16129)
Length = 357
Score = 103 bits (246), Expect = 4e-21
Identities = 66/183 (36%), Positives = 96/183 (52%), Gaps = 7/183 (3%)
Frame = +3
Query: 57 LTALLYK-PNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIM 233
+ A +Y+ P +LR+ P+PEI +VL+R+ GICGSD+H ++ G + IM
Sbjct: 7 MRAAVYRGPRELRVEPVPVPEIGPSDVLVRVHSCGICGSDLHSYKAG----MYIRPGQIM 62
Query: 234 GHEASGVVAKIGSKVKNLTVGDRV-AIEPGVPCRYCEFCKTGRYHLCPDMIFCATP-PVH 407
GHE G VA G V+ + GDRV GV C C +C +Y LCP++ +T +
Sbjct: 63 GHEFMGTVAAAGEDVEGVEEGDRVTGFSIGV-CGSCYWCSRQQYILCPELFRNSTGYGLP 121
Query: 408 GNLVRY--YKHA--ADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAG 575
G Y ++A +P + E A EP++VG+ A + GV G V+VLGAG
Sbjct: 122 GGFAEYVPIRNAVVGQSIHPVPSELDDETAATTEPVSVGVGAIEAAGVRPGDRVVVLGAG 181
Query: 576 PIG 584
IG
Sbjct: 182 MIG 184
>UniRef50_A3JMN6 Cluster: Dehydrogenase; n=4; Bacteria|Rep:
Dehydrogenase - Rhodobacterales bacterium HTCC2150
Length = 346
Score = 103 bits (246), Expect = 4e-21
Identities = 55/187 (29%), Positives = 92/187 (49%), Gaps = 1/187 (0%)
Frame = +3
Query: 42 MATDNLTALLYKPNDLRLVQTPIPEI-SEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLE 218
M ++A Y+ + +V+ ++ + EV +R+ GICG+D+H + L
Sbjct: 1 MIETKISAAFYRGDKSFVVEQTAAQVPNAGEVAVRVAYCGICGTDMHVYHGNMDARVGLN 60
Query: 219 EPMIMGHEASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATP 398
++GHE SG V IG+ V N+ +G +V + P C C C G +H+C + F
Sbjct: 61 R--VVGHEMSGTVEAIGANVTNVKMGQKVVVRPLDHCNDCPACDAGHFHICHQLNFLGLD 118
Query: 399 PVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGP 578
G + + A LPD + ++ AL+EP+AV H + + G V+V+G GP
Sbjct: 119 -TDGAMQEIWTVPAHTLHVLPDDLRLDHAALIEPVAVACHDVRMSDLKEGEDVVVIGGGP 177
Query: 579 IGLLTML 599
IG+L +
Sbjct: 178 IGILVAM 184
>UniRef50_Q565X2 Cluster: 6-hydroxycylohex-1-ene-1-carboxyl-CoA
dehydrogenase; n=1; uncultured bacterium|Rep:
6-hydroxycylohex-1-ene-1-carboxyl-CoA dehydrogenase -
uncultured bacterium
Length = 340
Score = 102 bits (245), Expect = 6e-21
Identities = 53/173 (30%), Positives = 92/173 (53%), Gaps = 2/173 (1%)
Frame = +3
Query: 75 KPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGV 254
K L++ P+P+I D++L+++ G+C +D+HY + G + P+++GHEASG+
Sbjct: 9 KDAGLKIEDIPVPQIKGDQILVKVAACGVCHTDLHYIEHGV--PTFKKPPIVLGHEASGI 66
Query: 255 VAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKH 434
V K G+ V N+ G RV I + C +C C+ GR ++C +M G Y
Sbjct: 67 VEKAGANVTNVKPGQRVLIPAVLTCGHCPACRQGRENICSNMTMLGN-HFDGAYAEYVAV 125
Query: 435 AADFCFKLPDHVTMEEGALL-EPLAVGIHACK-RGGVSAGHVVLVLGAGPIGL 587
A LP+ + ++E +++ + ++ HA K R V G V+V G G +G+
Sbjct: 126 PAKDVLGLPEAIPLQEASIIADAISTPYHAVKNRAQVKPGDTVVVFGCGGVGI 178
>UniRef50_A5V1N3 Cluster: Alcohol dehydrogenase GroES domain
protein; n=2; Roseiflexus|Rep: Alcohol dehydrogenase
GroES domain protein - Roseiflexus sp. RS-1
Length = 345
Score = 102 bits (245), Expect = 6e-21
Identities = 68/193 (35%), Positives = 98/193 (50%), Gaps = 7/193 (3%)
Frame = +3
Query: 42 MATDNLTALLYK-PNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLE 218
M T + AL++ P + L + P P EVL+ ++ VGICGS++ G G L
Sbjct: 1 MMTSTMDALVWLGPRRMELRREPAPTPEPGEVLVAVEAVGICGSEL----SGYLGQNSLR 56
Query: 219 EP-MIMGHEASGVVAKIGSKVKN----LTVGDRVAIEPGVPCRYCEFCKTGRYHLCPD-M 380
+P +IMGHEA+G +A + G RV P + C C+ C+ G+ +LC +
Sbjct: 57 KPPLIMGHEAAGRIAFDSDAALSDGSPARAGVRVTFNPLLTCGACDRCRAGKSNLCRNRQ 116
Query: 381 IFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVL 560
+ A P G Y AD C LPDHV++ G+L EPLA + A G +
Sbjct: 117 LISAHRP--GAFATYVAVPADLCIPLPDHVSLTLGSLTEPLACSVRAVAHTGTP--ERLA 172
Query: 561 VLGAGPIGLLTML 599
+LGAGPIGLL ++
Sbjct: 173 ILGAGPIGLLCLV 185
>UniRef50_A0QTC9 Cluster: 2-deoxy-scyllo-inosamine dehydrogenase;
n=1; Mycobacterium smegmatis str. MC2 155|Rep:
2-deoxy-scyllo-inosamine dehydrogenase - Mycobacterium
smegmatis (strain ATCC 700084 / mc(2)155)
Length = 360
Score = 101 bits (243), Expect = 1e-20
Identities = 59/176 (33%), Positives = 91/176 (51%), Gaps = 2/176 (1%)
Frame = +3
Query: 78 PNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVV 257
P L L I E ++R++ V +CG+D+H W+ G ++ P++ GHEA+G+V
Sbjct: 22 PGRLTLEDRKIASPHNGEAVVRVENVTLCGTDLHIWE----GEYLNPFPIVQGHEAAGIV 77
Query: 258 AKIG--SKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYK 431
+G + +LT G RV I P C C C+TGR ++C + + G L
Sbjct: 78 ESVGDPADASSLT-GTRVVISPVRSCGDCHACRTGRENVC-ERVSVLGCYEDGTLATRVV 135
Query: 432 HAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLLTML 599
++PD V E L EP ++ + A +RG AG + LVLG GPIGL+T++
Sbjct: 136 VPVSALHQVPDAVPSELAPLSEPASIALQAVRRGRPVAGELALVLGCGPIGLITIM 191
>UniRef50_A2R610 Cluster: Catalytic activity:; n=5;
Trichocomaceae|Rep: Catalytic activity: - Aspergillus
niger
Length = 356
Score = 101 bits (242), Expect = 1e-20
Identities = 65/182 (35%), Positives = 90/182 (49%), Gaps = 10/182 (5%)
Frame = +3
Query: 84 DLRLVQTPIP-EISEDEVLLRMDCVGICGSDVHYWQKG-----QCGHFVLEE--PMIMGH 239
D+R+ + P EV +R VGICGSD+H + G H + E P+ +GH
Sbjct: 11 DIRVEEIQEPGSCGVGEVKIRPAFVGICGSDIHEYLHGPSTIPSTTHPITGEKIPVTLGH 70
Query: 240 EASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLV 419
E SG + ++G V L VGD VAI+P + C C G + C ++ F G L
Sbjct: 71 EFSGTIIEVGEGVTRLQVGDNVAIKPNLFDGGCAACLGGWVNCCDNLGFVGFSGSAGGLS 130
Query: 420 RYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGH--VVLVLGAGPIGLLT 593
Y D +LP+ ++ GAL+EPL V HA R + H LV+GAGPIGL
Sbjct: 131 DYVVVKEDRAVRLPEGFDLDLGALVEPLTVAWHAVNRSSIQNDHARTALVVGAGPIGLAV 190
Query: 594 ML 599
+L
Sbjct: 191 LL 192
>UniRef50_Q8Y414 Cluster: Lmo2663 protein; n=14; Firmicutes|Rep:
Lmo2663 protein - Listeria monocytogenes
Length = 343
Score = 101 bits (241), Expect = 2e-20
Identities = 59/172 (34%), Positives = 92/172 (53%), Gaps = 2/172 (1%)
Frame = +3
Query: 81 NDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVA 260
+ + L P++ D+V +++ GICGSD+H + KG+ + P+ +GHE SGVV
Sbjct: 12 DQMELKDVEEPQVYGDKVKIKVAFTGICGSDIHTF-KGEYKNPTT--PVTLGHEFSGVVV 68
Query: 261 KIGSKVKNLTVGDRVAIEPGV-PCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHA 437
++G V ++ VGDRV E C C +CK Y+LC + T +G+ +
Sbjct: 69 EVGPDVTSIKVGDRVTSETTFETCGECIYCKEHDYNLCSNRRGIGT-QANGSFAEFVLSR 127
Query: 438 ADFCFKLPDHVTMEEGALLEPLAVGIH-ACKRGGVSAGHVVLVLGAGPIGLL 590
+ C L + +++E AL EPLA +H A ++ + VLV G GPIGLL
Sbjct: 128 EESCHVLDERISLEAAALTEPLACCVHSALEKTTIRPDDTVLVFGPGPIGLL 179
>UniRef50_Q1AVM7 Cluster: Alcohol dehydrogenase GroES-like protein;
n=1; Rubrobacter xylanophilus DSM 9941|Rep: Alcohol
dehydrogenase GroES-like protein - Rubrobacter
xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 341
Score = 101 bits (241), Expect = 2e-20
Identities = 57/173 (32%), Positives = 84/173 (48%), Gaps = 1/173 (0%)
Frame = +3
Query: 75 KPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGV 254
+P + + + P P EVLLR+ G+CGSDVH ++ G + P+ +GHE +G
Sbjct: 10 RPGEAGVAELPAPRPGPGEVLLRVAACGVCGSDVHAFRSDP-GFEWISTPVTLGHEFAGT 68
Query: 255 VAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKH 434
V +G V+ + GDRV C CE C G LCPD + G + Y
Sbjct: 69 VEALGPGVERVAPGDRVVAVAIQGCGRCELCLAGLTQLCPDRVAVGLSR-DGGMAEYAVM 127
Query: 435 AADFCFKLPDHVTMEEGALLEPLAVGIHAC-KRGGVSAGHVVLVLGAGPIGLL 590
+P+ + + AL EPL+V + A R G++ V+V G GPIG+L
Sbjct: 128 PEGHLVSVPEGLDLTLAALCEPLSVAVRAVDARAGIAPEGKVVVSGPGPIGIL 180
>UniRef50_A3S6P0 Cluster: L-threonine 3-dehydrogenase; n=2;
Bacteria|Rep: L-threonine 3-dehydrogenase -
Prochlorococcus marinus str. MIT 9211
Length = 379
Score = 101 bits (241), Expect = 2e-20
Identities = 57/168 (33%), Positives = 85/168 (50%)
Frame = +3
Query: 87 LRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKI 266
L +VQ P+PEI DEVL+++ GICG+D+H W + PMI GHE +G + +I
Sbjct: 50 LWMVQAPVPEIGPDEVLIKVRKTGICGTDIHIWNWDDWASATVPTPMITGHEFAGEIVEI 109
Query: 267 GSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADF 446
G V L++G R + E + + G++HL P G +Y + A
Sbjct: 110 GRDVTGLSIGQRCSGEGHLIGTDSRQSRAGKFHLDPGTRGIGVNE-QGAFAQYLRLPAFN 168
Query: 447 CFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLL 590
LP + E GA+L+PL +H + G VL+ GAGPIG++
Sbjct: 169 VVPLPASIPDEIGAILDPLGNAVHTALSFDL-LGEDVLITGAGPIGIM 215
>UniRef50_Q4PP82 Cluster: Putative zinc-containing alcohol
dehydrogenase; n=4; Endopterygota|Rep: Putative
zinc-containing alcohol dehydrogenase - Lysiphlebus
testaceipes (Greenbugs aphid parastoid)
Length = 340
Score = 101 bits (241), Expect = 2e-20
Identities = 64/174 (36%), Positives = 89/174 (51%), Gaps = 5/174 (2%)
Frame = +3
Query: 84 DLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEP--MIMGHEASGVV 257
+L LV IP+ DE+L+R+ GICG+D+H G F + + +GHE SGV+
Sbjct: 12 NLSLVHGEIPKPGPDEILVRVHYSGICGTDLHILD----GSFPAKSDGNLTLGHEFSGVI 67
Query: 258 AKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPV--HGNLVRYYK 431
IGS VK +G VAI+P C C+FC TG+YH C + T + G +
Sbjct: 68 EDIGSIVKGFKIGQSVAIDPNSGCNKCDFCHTGKYHFCDNGGINNTIGIFRDGGWSTHAV 127
Query: 432 HAADFCFKLPDHVTMEEGALLEPLAVGIHACK-RGGVSAGHVVLVLGAGPIGLL 590
+ LP V M + AL EPL+ H V+ G +LV+G+G IGLL
Sbjct: 128 VPESQVYLLPSGVEMPQAALAEPLSCLAHGWDIINPVTVGTNILVIGSGIIGLL 181
>UniRef50_A0JVX4 Cluster: Alcohol dehydrogenase GroES domain
protein; n=1; Arthrobacter sp. FB24|Rep: Alcohol
dehydrogenase GroES domain protein - Arthrobacter sp.
(strain FB24)
Length = 349
Score = 100 bits (239), Expect = 3e-20
Identities = 61/180 (33%), Positives = 90/180 (50%), Gaps = 6/180 (3%)
Frame = +3
Query: 63 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEE--PMIMG 236
A L+ P ++R+ P P ++++R+ ICG+D G HF L E P ++G
Sbjct: 4 ARLHSPGNIRVDDIPRPSADAGDIIIRVRAASICGTDRRIAANG---HFKLPEGTPRVLG 60
Query: 237 HEASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHG-- 410
HE +G + + GS+V VGDRV++ P V C C C G ++CP G
Sbjct: 61 HEFAGEIVEAGSEVSGYAVGDRVSVTPNVGCGTCPNCLVGLNNMCPSYEAFGITMDGGFQ 120
Query: 411 NLVRYYKHAAD--FCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIG 584
VR + A + F LP+ V E AL+EPL+ +A + V VL++GAGPIG
Sbjct: 121 EYVRIPRFALNRGNVFHLPETVGYAEAALVEPLSCCYNAVSKLDVRPDSTVLIMGAGPIG 180
>UniRef50_A1UG38 Cluster: Alcohol dehydrogenase GroES domain
protein; n=5; Actinomycetales|Rep: Alcohol dehydrogenase
GroES domain protein - Mycobacterium sp. (strain KMS)
Length = 362
Score = 99 bits (238), Expect = 4e-20
Identities = 62/196 (31%), Positives = 95/196 (48%), Gaps = 12/196 (6%)
Frame = +3
Query: 36 SDMATDNLTALL-YKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQK-----GQ 197
SD + + A++ + P D RL + +P+ E L+R++ VGIC SD+ + G
Sbjct: 2 SDQIPEKMQAVVCHGPRDYRLEEIAVPQRGPGEALIRVEAVGICASDLKCYHGAAKFWGD 61
Query: 198 CGHFVLEEPMIM-GHEASGVVAKIGSKVKN---LTVGDRVAIEPGVPCRYCEFCKTGRYH 365
E M++ GHE G V ++ + VGDRV E VPC C FCK G+YH
Sbjct: 62 ENRPAWAETMVIPGHEFVGTVVELDDDAAQRWGIAVGDRVVSEQIVPCWECRFCKRGQYH 121
Query: 366 LC-PDMIFCATPPVHGNLVRYYKHAAD-FCFKLPDHVTMEEGALLEPLAVGIHACKRGGV 539
+C P ++ G + Y + A+ K+ + A EPL+ +HA +R +
Sbjct: 122 MCQPHDLYGFKRRTPGAMASYMVYPAEALVHKVSKDIKPHHAAFAEPLSCSLHAVERAQI 181
Query: 540 SAGHVVLVLGAGPIGL 587
+ V+V G GPIGL
Sbjct: 182 TFEDTVVVAGCGPIGL 197
>UniRef50_Q1HPY0 Cluster: Zinc-containing alcohol dehydrogenase;
n=1; Bombyx mori|Rep: Zinc-containing alcohol
dehydrogenase - Bombyx mori (Silk moth)
Length = 342
Score = 99 bits (238), Expect = 4e-20
Identities = 57/168 (33%), Positives = 90/168 (53%), Gaps = 6/168 (3%)
Frame = +3
Query: 105 PIPEI-SEDEVLLRMDCVGICGSDVHYWQKGQCGHFVL--EEPMIMGHEASGVVAKIGSK 275
P+P+I ++D+V+++++ GICG+D+H Q G F E P+ +GHE SG + +G K
Sbjct: 20 PLPKIENDDDVIVKVEYSGICGTDLHIVQ----GEFPASKERPLPLGHEFSGTITDVGKK 75
Query: 276 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPV--HGNLVRYYKHAADFC 449
G +V ++P C C+FC+ G+Y C +T + G +Y K D
Sbjct: 76 -SVFRKGQKVVVDPNRACSLCDFCRKGKYQYCLTAGINSTVGIWRDGGWAQYVKVPQDQV 134
Query: 450 FKLPDHVTMEEGALLEPLAVGIHACKRGG-VSAGHVVLVLGAGPIGLL 590
+ LPD V+ E+G L EP + H R + G +L++GAG IG L
Sbjct: 135 YLLPDGVSTEQGGLCEPYSCVAHGYDRASPLLVGEKILIVGAGIIGNL 182
>UniRef50_Q9Z9U1 Cluster: Sorbitol dehydrogenase; n=14;
Bacillales|Rep: Sorbitol dehydrogenase - Bacillus
halodurans
Length = 343
Score = 99 bits (238), Expect = 4e-20
Identities = 54/165 (32%), Positives = 83/165 (50%), Gaps = 1/165 (0%)
Frame = +3
Query: 99 QTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGSKV 278
+ P P + +V +++ G+CGSD+H ++ GH+ + P+ +GHE SG + ++G V
Sbjct: 18 EKPEPTPGKHQVKIKVKYTGVCGSDIHTYE----GHYPVAAPVTLGHEFSGEIVELGEGV 73
Query: 279 KNLTVGDRVAIEPGVP-CRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFK 455
VGDRV E C C +C +G Y+LC G+ +Y +
Sbjct: 74 TGFNVGDRVTSETTYSICGKCSYCTSGDYNLCSHRKGLGNQQ-DGSFAKYVIARQESLHH 132
Query: 456 LPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLL 590
LP V A+ EPLA HA + ++ G +V+V G GPIGLL
Sbjct: 133 LPAGVDDRSAAMTEPLACTHHAIAKTSINKGDLVVVTGPGPIGLL 177
>UniRef50_Q5LVU9 Cluster: Sorbitol dehydrogenase, putative; n=13;
Alphaproteobacteria|Rep: Sorbitol dehydrogenase,
putative - Silicibacter pomeroyi
Length = 332
Score = 99.5 bits (237), Expect = 5e-20
Identities = 66/182 (36%), Positives = 87/182 (47%), Gaps = 5/182 (2%)
Frame = +3
Query: 57 LTALLYK-PNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEE-PMI 230
+ AL+Y P L L + P P E L+R+ VGICGSD+H + GH P+I
Sbjct: 1 MKALVYTGPETLALREMPNPVAGPGEQLIRIARVGICGSDMHAY----LGHDARRPAPLI 56
Query: 231 MGHEASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHG 410
+GHE +GV+ V G+RV + P V C C C+ GR +LCP + PP G
Sbjct: 57 LGHEVAGVI------VGGPRDGERVTVNPLVTCGACPACREGRDNLCPTRQIISMPPREG 110
Query: 411 NLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVS---AGHVVLVLGAGPI 581
Y +PD V + + AL EPLA G H + + A LVLG G I
Sbjct: 111 GFAEYVAMPEGNLVTVPDSVPLAQAALAEPLACGWHTVRLSLAALSGARDTALVLGGGAI 170
Query: 582 GL 587
GL
Sbjct: 171 GL 172
>UniRef50_Q1IQV6 Cluster: Alcohol dehydrogenase GroES-like; n=2;
Acidobacteria|Rep: Alcohol dehydrogenase GroES-like -
Acidobacteria bacterium (strain Ellin345)
Length = 374
Score = 99.5 bits (237), Expect = 5e-20
Identities = 62/186 (33%), Positives = 90/186 (48%), Gaps = 10/186 (5%)
Frame = +3
Query: 63 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 242
A+ + ND+RL P+PEI EVL+R+ GICG+D+ G H P I GHE
Sbjct: 22 AVYHGLNDVRLETVPVPEIGRGEVLIRVASCGICGTDLKKISTGS--H---SAPRIFGHE 76
Query: 243 ASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDM----IFCATPPVHG 410
+GV+A G V VGDRV +PC+ C +C+ + CP + P G
Sbjct: 77 TAGVIAAAGDGVTKFQVGDRVLAFHHIPCQECYYCRHKVFAQCPTYKKVGVTAGYEPSGG 136
Query: 411 NLVRYYKHAADF------CFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGA 572
Y + D+ KLPDHV+ + +EP+ A + + +G VLV+G
Sbjct: 137 GFSEYVR-VMDWIVDRGGVVKLPDHVSYDLATFVEPVNTCQKAIETMALKSGETVLVIGQ 195
Query: 573 GPIGLL 590
G IG++
Sbjct: 196 GAIGMI 201
>UniRef50_P0A9S4 Cluster: Galactitol-1-phosphate 5-dehydrogenase;
n=27; cellular organisms|Rep: Galactitol-1-phosphate
5-dehydrogenase - Escherichia coli O157:H7
Length = 346
Score = 99.5 bits (237), Expect = 5e-20
Identities = 59/171 (34%), Positives = 88/171 (51%), Gaps = 1/171 (0%)
Frame = +3
Query: 87 LRLVQTPIPEIS-EDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAK 263
+R+ ++ IPEI +DEV +++ G+CGSD+ K ++ P+ +GHE SG +
Sbjct: 12 VRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAHYY----PITLGHEFSGYIDA 67
Query: 264 IGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAAD 443
+GS V +L GD VA P +PC C C G Y C F + G Y
Sbjct: 68 VGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSRR-DGGFAEYIVVKRK 126
Query: 444 FCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLLTM 596
F LP + +E+GA +EP+ VG+HA V+++GAG IGLL +
Sbjct: 127 NVFALPTDMPIEDGAFIEPITVGLHAFHLAQGCENKNVIIIGAGTIGLLAI 177
>UniRef50_Q2G759 Cluster: GroES-related; n=1; Novosphingobium
aromaticivorans DSM 12444|Rep: GroES-related -
Novosphingobium aromaticivorans (strain DSM 12444)
Length = 335
Score = 99.1 bits (236), Expect = 7e-20
Identities = 58/173 (33%), Positives = 85/173 (49%)
Frame = +3
Query: 69 LYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEAS 248
L+KP + + P P E +V++++ GICGSD+H + G ++GHE +
Sbjct: 9 LHKPLAIDTIPDPTP--GEGDVVVKVGRCGICGSDLHMTEDPAYGQGA---GSVLGHEFA 63
Query: 249 GVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYY 428
G V +G V+ L GD V++ P C C C+TG C G +
Sbjct: 64 GEVVALGKGVEGLRTGDLVSVIPLQSCGQCHSCRTGEVQWCERFGLQG-----GGYAEFA 118
Query: 429 KHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGL 587
+ C +LP +M +GA++EPLAV +H + G VLVLGAGPIGL
Sbjct: 119 LTRPNQCVRLPASASMADGAIVEPLAVALHGLALSRMKIGDKVLVLGAGPIGL 171
>UniRef50_A1RYE2 Cluster: Alcohol dehydrogenase GroES domain
protein; n=1; Thermofilum pendens Hrk 5|Rep: Alcohol
dehydrogenase GroES domain protein - Thermofilum pendens
(strain Hrk 5)
Length = 398
Score = 99.1 bits (236), Expect = 7e-20
Identities = 63/182 (34%), Positives = 92/182 (50%), Gaps = 21/182 (11%)
Frame = +3
Query: 105 PIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEE----PMIMGHEASGVVAKIGS 272
P+PE DE+L+R+ VGICGSD+H+ + G+ + P+++GHE SGVV K+G+
Sbjct: 47 PVPEPKPDEILIRVKAVGICGSDIHFLETDSEGYILYPGLTRFPVVIGHEFSGVVEKVGT 106
Query: 273 KVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLC------PDMIFCATPPVH-GNLVRYYK 431
VK GD V E C C+ C++ ++ C D+ F H G + Y
Sbjct: 107 NVKTFKPGDMVTSEEMFWCGECDACRSVDFNHCLRLNDPADLEFGELGFTHDGAMADYVV 166
Query: 432 HAADFCFKL--------PDHVTMEEGALLEPLAVGIHA--CKRGGVSAGHVVLVLGAGPI 581
A + +K+ + E G+L+EP +V HA + GG G V V GAGPI
Sbjct: 167 VKAKYAWKIDSLLDRYGSEDKAFEAGSLVEPTSVAYHAMFTRAGGFKPGAYVAVWGAGPI 226
Query: 582 GL 587
GL
Sbjct: 227 GL 228
>UniRef50_A4QH16 Cluster: Putative uncharacterized protein; n=1;
Corynebacterium glutamicum R|Rep: Putative
uncharacterized protein - Corynebacterium glutamicum
(strain R)
Length = 363
Score = 98.7 bits (235), Expect = 9e-20
Identities = 55/164 (33%), Positives = 83/164 (50%), Gaps = 2/164 (1%)
Frame = +3
Query: 111 PEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKI--GSKVKN 284
P I + M V +CG+D H W + E P+I GHEA+G++ ++ +
Sbjct: 35 PAIVPGSARISMAAVTLCGTDAHIWDDD----YASELPIIQGHEAAGIITEMDPSDEGNG 90
Query: 285 LTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPD 464
VGDRV I P C C C GR + C +M G+LV FK+PD
Sbjct: 91 FNVGDRVVICPMFYCGKCYACSVGRVNACKEMSVYGCYE-DGSLVDEQVVPYANLFKIPD 149
Query: 465 HVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLLTM 596
+ ++ ++EP+++ + ACKRG +G V+V GAGPIG+L +
Sbjct: 150 SLPLDLAPIVEPISIAMQACKRGRPVSGEKVIVNGAGPIGVLAV 193
>UniRef50_Q92YT8 Cluster: Putative; n=2; Alphaproteobacteria|Rep:
Putative - Rhizobium meliloti (Sinorhizobium meliloti)
Length = 341
Score = 98.3 bits (234), Expect = 1e-19
Identities = 57/177 (32%), Positives = 90/177 (50%), Gaps = 1/177 (0%)
Frame = +3
Query: 63 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEE-PMIMGH 239
A+L +P + + IPEI +VL+R+ GICG+D+H + GH+ + P++ GH
Sbjct: 4 AVLVEPRRFEVREVGIPEIGPADVLIRVTRAGICGTDLHIFN----GHYAADRLPIVPGH 59
Query: 240 EASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLV 419
E G +A+IG+ V +L G RV + + C C +C+ C ++ G
Sbjct: 60 EFCGTIAEIGASVTHLKTGMRVVADINIGCGNCYWCRRNEVLNCGEVEQIGIGR-DGAFA 118
Query: 420 RYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLL 590
+Y +PD V AL+EP+A + A ++ G + G +VLGAGPIG L
Sbjct: 119 QYVALPGRLVLPVPDGVPEAVLALVEPVACVVRAARKAGAAFGRSGVVLGAGPIGNL 175
>UniRef50_Q8DK96 Cluster: Tll0970 protein; n=6; Cyanobacteria|Rep:
Tll0970 protein - Synechococcus elongatus
(Thermosynechococcus elongatus)
Length = 373
Score = 98.3 bits (234), Expect = 1e-19
Identities = 61/189 (32%), Positives = 90/189 (47%), Gaps = 13/189 (6%)
Frame = +3
Query: 63 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHF-VLEEPMIMGH 239
A+LY D+R+ P P EV++R+ CG+D+ W++G GH +L P++ GH
Sbjct: 28 AVLYGKEDVRIETVPDPTPGPGEVVIRVRAATTCGTDLKVWRRG--GHARMLTPPILFGH 85
Query: 240 EASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLV 419
EA+G + +G+ V VGDRV PC C +C+ + LCP + F +G
Sbjct: 86 EAAGEIVALGAGVTGWQVGDRVVANNSAPCGQCFYCQRQAFSLCPHLEF-----NNGTFA 140
Query: 420 RYYKHAADF----CFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHV--------VLV 563
Y K A +P+ + AL EPLA +H R G V ++V
Sbjct: 141 EYLKLPASIVRQNLLPIPESLPFALAALTEPLACVLHGVARSGFDPAMVATWPSPPQIVV 200
Query: 564 LGAGPIGLL 590
LG G IGL+
Sbjct: 201 LGDGAIGLM 209
>UniRef50_Q1IJN0 Cluster: Alcohol dehydrogenase GroES-like; n=1;
Acidobacteria bacterium Ellin345|Rep: Alcohol
dehydrogenase GroES-like - Acidobacteria bacterium
(strain Ellin345)
Length = 350
Score = 98.3 bits (234), Expect = 1e-19
Identities = 51/166 (30%), Positives = 84/166 (50%)
Frame = +3
Query: 99 QTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGSKV 278
+ P+P+ +EVL+++ ICG+D+H + Q ++ P+I GHE G V +GS+V
Sbjct: 21 EVPVPKFGPNEVLVKVKVASICGTDLHIYNWDQWAQRRIKPPLIPGHEFCGDVVAVGSEV 80
Query: 279 KNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKL 458
+ GD V+ E V C C C+TG+ H+C + +G Y +KL
Sbjct: 81 TLVKEGDFVSAEMHVNCGKCLQCRTGQAHICQHVKIIGV-DANGAFAEYVVIPESNIWKL 139
Query: 459 PDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLLTM 596
+ E ++L+PL +H G ++A V + G GPIGL ++
Sbjct: 140 DPAIPQEYASILDPLGNAVHTVLAGDIAA-KTVAITGCGPIGLFSI 184
>UniRef50_A6VLA0 Cluster: Alcohol dehydrogenase GroES domain
protein; n=1; Actinobacillus succinogenes 130Z|Rep:
Alcohol dehydrogenase GroES domain protein -
Actinobacillus succinogenes 130Z
Length = 339
Score = 98.3 bits (234), Expect = 1e-19
Identities = 54/176 (30%), Positives = 92/176 (52%), Gaps = 2/176 (1%)
Frame = +3
Query: 75 KPNDLRLVQTPIPEIS-EDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASG 251
+P +L + P P ++ +D+V++++ GICGSD+ + G + + P I+GHE G
Sbjct: 8 QPFELTVADVPAPTVTKDDDVIIKVAFGGICGSDIGIYTGGNS---LAKYPAIIGHEFVG 64
Query: 252 VVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYK 431
V + G V ++ VGD V + C +C C+TG +++C ++ G Y K
Sbjct: 65 TVVETGKAVTHVKVGDYVVSDIVNSCGHCYACRTGHHNVCKNLQVTGVHS-QGGFAEYAK 123
Query: 432 HAADFCFKL-PDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLLTM 596
AD + + + + + L+EP AVG+ R ++AG V+V G+GP GL M
Sbjct: 124 TRADNVYLVDTNKIPHKTACLIEPYAVGVEINTRASIAAGDKVVVFGSGPAGLAVM 179
>UniRef50_A5D5N1 Cluster: Threonine dehydrogenase and related
Zn-dependent dehydrogenases; n=1; Pelotomaculum
thermopropionicum SI|Rep: Threonine dehydrogenase and
related Zn-dependent dehydrogenases - Pelotomaculum
thermopropionicum SI
Length = 343
Score = 98.3 bits (234), Expect = 1e-19
Identities = 52/173 (30%), Positives = 86/173 (49%), Gaps = 1/173 (0%)
Frame = +3
Query: 75 KPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGV 254
+P + L P P + DEVL+R+ +CGSD+H ++ + F ++ P+I+GHE SG
Sbjct: 10 RPGAVNLRSVPEPRPAGDEVLIRVQSAAVCGSDLHAYEYPKSYEF-MKVPVILGHEYSGY 68
Query: 255 VAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKH 434
V +G +V GDRV E C C C+ GR ++C + V G + +
Sbjct: 69 VEAVGPQVTLFKPGDRVLGESNRYCGVCPNCRRGRTNICDSNLMTGL-HVDGGMAEFIAV 127
Query: 435 AADFCFKLPDHVTMEEGALLEPLAVGIHAC-KRGGVSAGHVVLVLGAGPIGLL 590
+P++++ +E L +P +V HA G+ +V V G G +GL+
Sbjct: 128 PQKLVHHIPENLSFDEATLAQPCSVSFHAVFDNSGIRPNDMVAVFGPGIVGLM 180
>UniRef50_UPI000051A87A Cluster: PREDICTED: similar to R04B5.5; n=1;
Apis mellifera|Rep: PREDICTED: similar to R04B5.5 - Apis
mellifera
Length = 338
Score = 97.9 bits (233), Expect = 2e-19
Identities = 60/177 (33%), Positives = 91/177 (51%), Gaps = 5/177 (2%)
Frame = +3
Query: 75 KPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEP--MIMGHEAS 248
K + L L + +P ++V +R+ GICG+D+H + G F ++ + +GHE +
Sbjct: 9 KNHTLALRRADVPNPGPNDVRIRIAYSGICGTDLHILE----GSFPCKKDGFLTLGHEFA 64
Query: 249 GVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVH--GNLVR 422
G V IGS VKN VG RVA++P C C +C G Y C +T ++ G
Sbjct: 65 GTVDAIGSSVKNFKVGQRVAVDPNSGCNTCNYCHDGSYQHCSAGGINSTIGIYKDGGFST 124
Query: 423 YYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKR-GGVSAGHVVLVLGAGPIGLL 590
+ + +PD V + + L+EPL+ H K+ V+ G VLV+GAG IGLL
Sbjct: 125 HAIVPESQVYLIPDDVELHQAVLVEPLSCLAHGWKKLNSVNVGSNVLVIGAGIIGLL 181
>UniRef50_Q62K93 Cluster: Oxidoreductase, zinc-binding dehydrogenase
family; n=41; Bacteria|Rep: Oxidoreductase, zinc-binding
dehydrogenase family - Burkholderia mallei (Pseudomonas
mallei)
Length = 353
Score = 97.9 bits (233), Expect = 2e-19
Identities = 62/189 (32%), Positives = 98/189 (51%), Gaps = 11/189 (5%)
Frame = +3
Query: 57 LTALL-YKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDV--HYWQKGQCGHFV--LEE 221
+TA++ + P D R+ + P + E+++R+ GIC SD H K G ++
Sbjct: 1 MTAIVCHAPEDYRVERVAKPRANARELVIRIGACGICASDCKCHAGAKMFWGGPSPWVKA 60
Query: 222 PMIMGHEASGVVAKIGSKVKN---LTVGDRVAIEPGVPCRYCEFCKTGRYHLCP-DMIFC 389
P+I GHE G V +G + +GDRV E VPC C +CK+G+Y +C IF
Sbjct: 61 PVIPGHEFFGYVEALGEGAAEHFGVALGDRVIAEQIVPCGTCRYCKSGQYWMCEVHHIFG 120
Query: 390 ATPPV-HGNLVRYYK-HAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLV 563
V G + Y + + +P +++E+ A++EPLA IH RG + VV++
Sbjct: 121 FQREVADGGMAEYMRIPSGAIVHPIPLGISLEDAAIIEPLACAIHTVNRGDIQLDDVVVI 180
Query: 564 LGAGPIGLL 590
GAGP+GL+
Sbjct: 181 AGAGPLGLM 189
>UniRef50_A0V7I1 Cluster: Alcohol dehydrogenase GroES-like; n=2;
Comamonadaceae|Rep: Alcohol dehydrogenase GroES-like -
Delftia acidovorans SPH-1
Length = 567
Score = 97.9 bits (233), Expect = 2e-19
Identities = 61/171 (35%), Positives = 82/171 (47%), Gaps = 5/171 (2%)
Frame = +3
Query: 87 LRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEE-PMIMGHEASGVVAK 263
L L Q +P EVLLR+ G+CG+D+H + + HF+ P+ +GHE SG +A
Sbjct: 229 LTLTQADMPAPGPGEVLLRVHSAGVCGTDLHIAEWTRSYHFLTPALPVTIGHEFSGEIAA 288
Query: 264 IGSKVKNL----TVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYK 431
+G +NL TVG VA+ P V C C C +G + C +G +
Sbjct: 289 LGEGAENLAPGLTVGQMVAVRPSVTCGRCAACTSGNFDGCTTRRGIGVLR-NGGFAPWAA 347
Query: 432 HAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIG 584
C +P V + AL EPL V A + GV GH VLVLG G IG
Sbjct: 348 VPLRNCVPVPAGVQGDVAALAEPLTVSHEAVRTAGVRPGHRVLVLGPGNIG 398
>UniRef50_Q8ELI9 Cluster: Sorbitol dehydrogenase; n=2;
Bacillaceae|Rep: Sorbitol dehydrogenase - Oceanobacillus
iheyensis
Length = 326
Score = 97.5 bits (232), Expect = 2e-19
Identities = 55/161 (34%), Positives = 86/161 (53%)
Frame = +3
Query: 114 EISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGSKVKNLTV 293
++S+DEV +R+ GICGSD+ + KG+ H P++ GHE G V + G +
Sbjct: 22 KLSDDEVRIRLIYGGICGSDISVF-KGKLPH--ANYPVVPGHELIGTVIETGKSAADFA- 77
Query: 294 GDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVT 473
G RVAI P C CE+CK G+ ++C + G + +A + LPD +T
Sbjct: 78 GKRVAIMPNSFCGKCEYCKVGKTNICTEKQSLGINR-DGGFAEEFVISAKYVLSLPDQLT 136
Query: 474 MEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLLTM 596
E+ L+EPLAV +HA K+ ++ V ++G G G+L +
Sbjct: 137 NEKAVLIEPLAVIVHAMKKVVITEETKVAIIGCGNEGMLAI 177
>UniRef50_A4AMR5 Cluster: Zn-dependent alcohol dehydrogenase; n=2;
Flavobacteriales|Rep: Zn-dependent alcohol dehydrogenase
- Flavobacteriales bacterium HTCC2170
Length = 337
Score = 97.5 bits (232), Expect = 2e-19
Identities = 56/171 (32%), Positives = 84/171 (49%)
Frame = +3
Query: 75 KPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGV 254
KP L + P + LL+++ VGICG+D+H + Q P I+GHE +
Sbjct: 8 KPGKFLLKEKKAPLGVKGHALLKINKVGICGTDLHAYAGNQA---FFTYPRILGHELAAE 64
Query: 255 VAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKH 434
+ I + K L GD+V I P V C C C+ G+ + C +M G +
Sbjct: 65 IISIPTNQKGLKAGDKVVIMPYVSCNTCIACRNGKNNCCTNMQVLGI-HTDGGMQEKINV 123
Query: 435 AADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGL 587
+ K + +T +E A++EPLA+G HA R G+S +V+G GPIGL
Sbjct: 124 PIELLLK-ANELTDDEIAIVEPLAIGAHAISRSGLSKDETAVVVGCGPIGL 173
>UniRef50_O35045 Cluster: Zinc-containing alcohol dehydrogenase;
n=5; Bacillus|Rep: Zinc-containing alcohol dehydrogenase
- Bacillus subtilis
Length = 339
Score = 97.1 bits (231), Expect = 3e-19
Identities = 60/175 (34%), Positives = 87/175 (49%), Gaps = 1/175 (0%)
Frame = +3
Query: 75 KPNDLRLVQTPIPEIS-EDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASG 251
K DL + P +S +DEVL+++ VGICGSD+H + G L P ++GHE +G
Sbjct: 8 KAYDLVTAEVKKPVLSKDDEVLVKVKRVGICGSDMHIYH-GTNPLATL--PRVIGHEVTG 64
Query: 252 VVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYK 431
V +G+ V++L GD V IEP C C C+ GR ++C + G + Y
Sbjct: 65 QVEAVGANVQSLKPGDHVVIEPISYCGSCYACRKGRPNVCAKLSVFGVHE-DGGMREYIV 123
Query: 432 HAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLLTM 596
+ + EE + EP +G A RG V G VL+ GAGPIG+ +
Sbjct: 124 LPERQLHAVSKDLPWEEAVMAEPYTIGAQAVWRGQVEKGDTVLIQGAGPIGICVL 178
>UniRef50_Q39TG2 Cluster: Alcohol dehydrogenase superfamily,
zinc-containing; n=1; Geobacter metallireducens
GS-15|Rep: Alcohol dehydrogenase superfamily,
zinc-containing - Geobacter metallireducens (strain
GS-15 / ATCC 53774 / DSM 7210)
Length = 340
Score = 96.3 bits (229), Expect = 5e-19
Identities = 59/176 (33%), Positives = 88/176 (50%), Gaps = 1/176 (0%)
Frame = +3
Query: 75 KPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGV 254
KP + + PIP + EV++ + GICG+D+H + L + ++GHE +G
Sbjct: 11 KPLAIESLNDPIP--LDGEVIVNVKACGICGTDIHATADKEMR---LADGTVLGHEFAGE 65
Query: 255 VAKIGSKVK-NLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYK 431
+ ++G +V GDR+ P + C +C C TG C G Y +
Sbjct: 66 IVEVGPQVAVGWAQGDRLCTLPYIGCGHCLACLTGMPWQCKLKKVIGIQTA-GGFAEYAR 124
Query: 432 HAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLLTML 599
+ +LP V+ +EGAL+EPLA+G+HA + AG VLV GAGPIGL L
Sbjct: 125 VHVNEAVRLPVSVSWQEGALVEPLAIGLHAVRLSRGVAGKSVLVTGAGPIGLAVAL 180
>UniRef50_A5ZM46 Cluster: Putative uncharacterized protein; n=2;
Ruminococcus|Rep: Putative uncharacterized protein -
Ruminococcus obeum ATCC 29174
Length = 350
Score = 96.3 bits (229), Expect = 5e-19
Identities = 54/178 (30%), Positives = 86/178 (48%)
Frame = +3
Query: 63 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 242
A++ D++ + P++++ V +++ GICGSD+ H V P+++GHE
Sbjct: 4 AVVVANEDVQYQEVEEPKVTKGTVKIKVRYSGICGSDI----PRVLNHGVHFYPIVLGHE 59
Query: 243 ASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVR 422
SG V ++G V + VGDRV+ P +PC C+ C+ G + LC F + G+
Sbjct: 60 FSGDVVEVGEGVTKVKVGDRVSGAPLLPCMKCDDCQKGNFSLCKHYSFIGSRQ-QGSNAD 118
Query: 423 YYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLLTM 596
Y V E+GA+ EP V IH + G V +LG G +G+ TM
Sbjct: 119 YVVVPEQNAVPFDKTVPYEQGAMFEPATVAIHGVFQNDYHGGEYVAILGGGTVGMFTM 176
>UniRef50_Q0UDN4 Cluster: Putative uncharacterized protein; n=2;
Pezizomycotina|Rep: Putative uncharacterized protein -
Phaeosphaeria nodorum (Septoria nodorum)
Length = 363
Score = 96.3 bits (229), Expect = 5e-19
Identities = 60/184 (32%), Positives = 92/184 (50%), Gaps = 9/184 (4%)
Frame = +3
Query: 63 ALLYKPNDLRLVQTPIPE--ISEDEVLLRMDCVGICGSDVHYWQKGQC-----GHFVLEE 221
A Y D+R ++T + E ++ + VGICG+D+H + G H V +
Sbjct: 4 ARYYGKEDIR-IETDVDEQKCGAGQIRIAPAYVGICGTDLHEYLGGPTFAPTKPHPVTHD 62
Query: 222 --PMIMGHEASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCAT 395
P+ +GHE SG V ++G V + +VG + ++P + C C CK G ++C + F
Sbjct: 63 TIPITLGHEFSGTVTELGPNVTSFSVGQPIVVQPTIYCGKCHACKAGVENVCYNGGFIGL 122
Query: 396 PPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAG 575
G L LPD+V ++ GAL+EPL+V HA ++ VV+VLG G
Sbjct: 123 SGGGGGLSDSVVVPESAVLALPDNVPLDIGALVEPLSVAWHAISAAPLTPDSVVMVLGGG 182
Query: 576 PIGL 587
PIGL
Sbjct: 183 PIGL 186
>UniRef50_Q1PUQ4 Cluster: Similar to zinc-containing dehydrogenase;
n=1; Candidatus Kuenenia stuttgartiensis|Rep: Similar to
zinc-containing dehydrogenase - Candidatus Kuenenia
stuttgartiensis
Length = 386
Score = 95.9 bits (228), Expect = 6e-19
Identities = 57/191 (29%), Positives = 95/191 (49%), Gaps = 13/191 (6%)
Frame = +3
Query: 54 NLTALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVL----EE 221
N+ + +++ + +P + +DE+L+R+ GICGSD H ++ + G+ + E
Sbjct: 29 NVGSQVWQHTQFEVKDVSVPNLQDDEILVRIKSCGICGSDTHLYETDKDGYIIFSGVTEL 88
Query: 222 PMIMGHEASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPP 401
P I+GHE SG+V + G V+N++ GD +A E + C C C++G + C I
Sbjct: 89 PRIIGHELSGIVEQTGKNVRNVSKGDWIAAESIMWCGMCHACRSGSPNQC-KYIKLMGLS 147
Query: 402 VHGNLVRYYKHAADFCFKLPD--HVTMEE-----GALLEPLAVGIHA--CKRGGVSAGHV 554
G Y +C+++ D + E+ GAL+EP+ + GG G
Sbjct: 148 ADGAFAEYIAINERYCWEINDFREIYSEDEAFDIGALIEPVGCAYNGLFIVGGGFQPGAT 207
Query: 555 VLVLGAGPIGL 587
V+V G GPIGL
Sbjct: 208 VVVYGTGPIGL 218
>UniRef50_A4XGJ9 Cluster: Alcohol dehydrogenase, zinc-binding domain
protein; n=1; Caldicellulosiruptor saccharolyticus DSM
8903|Rep: Alcohol dehydrogenase, zinc-binding domain
protein - Caldicellulosiruptor saccharolyticus (strain
ATCC 43494 / DSM 8903)
Length = 344
Score = 95.5 bits (227), Expect = 9e-19
Identities = 55/168 (32%), Positives = 84/168 (50%), Gaps = 3/168 (1%)
Frame = +3
Query: 105 PIPEISEDEVLLRMDCVGICGSDV--HYWQKGQCGHFVLEEPMIMGHEASGVVAKIGSKV 278
PIP+ + EVL+++ IC SD+ +Y G +I GHE +G + ++G V
Sbjct: 21 PIPKPKDGEVLVKIKASAICRSDMSLYYGNPVVGGEIAKSGSIIPGHEPAGEIVEVGKGV 80
Query: 279 KNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKL 458
N+ GDRVAI V C C +CK+G +C C +HG Y A+ C K+
Sbjct: 81 TNVKPGDRVAIYLAVSCGECLYCKSGYKMMC-KQFKCIGFDLHGGDAEYMVVPAENCMKI 139
Query: 459 PDHVTMEEGAL-LEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLLTML 599
PD ++ A+ + + HA KR G+S +V + G GP+G +L
Sbjct: 140 PDEMSYITAAVSTDAIGTLYHAQKRMGISGRDIVAIYGIGPMGAAGIL 187
>UniRef50_Q1QWS0 Cluster: Alcohol dehydrogenase GroES-like protein;
n=1; Chromohalobacter salexigens DSM 3043|Rep: Alcohol
dehydrogenase GroES-like protein - Chromohalobacter
salexigens (strain DSM 3043 / ATCC BAA-138 / NCIMB13768)
Length = 349
Score = 95.1 bits (226), Expect = 1e-18
Identities = 54/176 (30%), Positives = 86/176 (48%)
Frame = +3
Query: 60 TALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGH 239
T + +P + L P P+ + E +LR+ VGICG+D+H + Q +F P ++GH
Sbjct: 3 TLVCTQPRHMELRDVPEPQCAPGEAMLRIRRVGICGTDIHAYGGNQ-PYFTY--PRVLGH 59
Query: 240 EASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLV 419
E SG + +G V VG + P + C C C+ G+ + C M G +
Sbjct: 60 ELSGDIVGVGEGVDESLVGHSAYVIPYLHCGECRACRQGKTNCCQHMQVIGVHR-DGGMA 118
Query: 420 RYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGL 587
Y D + E+ AL+E L++G HA +R + A + +V+GAGPIG+
Sbjct: 119 EYLSVPVDHLVT-SSTLDAEQLALVECLSIGAHAVRRSAIEADELAVVVGAGPIGI 173
>UniRef50_A6LR91 Cluster: Alcohol dehydrogenase GroES domain
protein; n=1; Clostridium beijerinckii NCIMB 8052|Rep:
Alcohol dehydrogenase GroES domain protein - Clostridium
beijerinckii NCIMB 8052
Length = 373
Score = 95.1 bits (226), Expect = 1e-18
Identities = 56/188 (29%), Positives = 95/188 (50%), Gaps = 11/188 (5%)
Frame = +3
Query: 69 LYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKG-QCGHF-------VLEEP 224
+YK + + + + + D++ ++M VG+CGSD+H + + G+ + EE
Sbjct: 26 IYKNPHIMIEERTLGTLDPDKIRIQMLYVGVCGSDIHILKSNPETGYICSSVPVEIPEEG 85
Query: 225 MIMGHEASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPD--MIFCATP 398
I+GHE G+V +GS VK + G V +E + C C+ CK G ++ C + +I
Sbjct: 86 RIIGHEGVGLVLDVGSNVKEIEKGMYVTLESILVCNNCDVCKRGDFNQCRNAKLIGLEVD 145
Query: 399 PVHGNLVRYYKHAA-DFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAG 575
V GN+V + A D + + A +EP+ V AC+ + AG VV++ G G
Sbjct: 146 GVMGNVVDVNSNLAHDVTGYIKSEDDLIAMACVEPMGVAYDACENAKIKAGDVVVIFGGG 205
Query: 576 PIGLLTML 599
PIG+ T +
Sbjct: 206 PIGIYTAM 213
>UniRef50_A4FJI0 Cluster: Putative zinc-binding alcohol
dehydrogenase; n=1; Saccharopolyspora erythraea NRRL
2338|Rep: Putative zinc-binding alcohol dehydrogenase -
Saccharopolyspora erythraea (strain NRRL 23338)
Length = 334
Score = 95.1 bits (226), Expect = 1e-18
Identities = 66/181 (36%), Positives = 87/181 (48%), Gaps = 7/181 (3%)
Frame = +3
Query: 69 LYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEAS 248
++ D+RL +PE ++ EVLLR+ VGICGSD+HY+ G+ G V+ EP GHE S
Sbjct: 6 IHGAEDMRLEDVAVPEPADGEVLLRVRYVGICGSDLHYYFHGKNGENVVREPFAPGHEFS 65
Query: 249 GVVAKIGSKVKNLTVGDRVAIEP---GVPCRYCEFCKTGRYHLCP--DMIFCAT--PPVH 407
V S G V + P G P R HL P D + A P
Sbjct: 66 ATVEADPS--GQWAKGTPVTVHPARYGTPVEGI----ADRPHLWPGGDYLGSAADFPHRQ 119
Query: 408 GNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGL 587
G Y +LP+ +++ + AL EPL V +HA G G LVLGAGP+GL
Sbjct: 120 GAAAEYVLVEKPMLRRLPEGLSLRDAALAEPLGVALHALTIAGGHLGDRALVLGAGPVGL 179
Query: 588 L 590
L
Sbjct: 180 L 180
>UniRef50_A0JVW4 Cluster: Alcohol dehydrogenase GroES domain
protein; n=2; Arthrobacter|Rep: Alcohol dehydrogenase
GroES domain protein - Arthrobacter sp. (strain FB24)
Length = 343
Score = 95.1 bits (226), Expect = 1e-18
Identities = 59/189 (31%), Positives = 88/189 (46%)
Frame = +3
Query: 33 ASDMATDNLTALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFV 212
++ + T A+L + + P P L+R+ GICGSD G+ H
Sbjct: 4 STTLTTGIRAAVLSAAHHFEVQHVPKPSPGPGAALVRVSYTGICGSDFPIVD-GR--HPR 60
Query: 213 LEEPMIMGHEASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCA 392
P+I+GHE +G++ + G + G RVA+ P +PC C C G H+C ++
Sbjct: 61 AAMPLILGHEITGILEEPGGS--GIPAGTRVAVNPLLPCGQCGACLKGLGHVCRNLRLLG 118
Query: 393 TPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGA 572
V G++ F E AL EPLAV +HA +R ++ G VL+ GA
Sbjct: 119 ID-VPGSMTEVLAVPVSNLFAFSADAPATEAALAEPLAVAVHAVRRSRLAPGEKVLIFGA 177
Query: 573 GPIGLLTML 599
GPIG+L L
Sbjct: 178 GPIGILVAL 186
>UniRef50_Q8Z6Z4 Cluster: Starvation sensing protein RspB; n=1;
Salmonella typhi|Rep: Starvation sensing protein RspB -
Salmonella typhi
Length = 287
Score = 94.7 bits (225), Expect = 1e-18
Identities = 48/178 (26%), Positives = 89/178 (50%), Gaps = 1/178 (0%)
Frame = +3
Query: 66 LLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEE-PMIMGHE 242
++ KPN L + + + + EV +++ GICGSD H ++ GH + P ++GHE
Sbjct: 5 VIEKPNTLTIETRALLQPASGEVRIKVKLAGICGSDSHIYR----GHNPFAKYPRVIGHE 60
Query: 243 ASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVR 422
GV+ +G V +G+RV+++P + C +C C G+ ++C ++ G
Sbjct: 61 FFGVIDAVGDNVNRDRIGERVSVDPVISCGHCYPCSVGKPNVCTSLVVLGVHR-DGGFSE 119
Query: 423 YYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLLTM 596
Y A ++PD++ ++EP + + + + V L+ GAGP+GL T+
Sbjct: 120 YAVAPARNAHRIPDNIADHHAVMVEPFTIAANVTGQVNPTEQDVALIYGAGPMGLTTV 177
>UniRef50_A0IRE9 Cluster: Alcohol dehydrogenase GroES-like; n=1;
Serratia proteamaculans 568|Rep: Alcohol dehydrogenase
GroES-like - Serratia proteamaculans 568
Length = 341
Score = 93.9 bits (223), Expect = 3e-18
Identities = 58/182 (31%), Positives = 87/182 (47%)
Frame = +3
Query: 42 MATDNLTALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEE 221
MA++ + KP L + PIP EVLL+M +G+CGSD+H + Q +++
Sbjct: 1 MASEMKVLVCIKPGQLSQQRRPIPLPGTGEVLLKMCALGVCGSDIHAFHGRQP---MMQY 57
Query: 222 PMIMGHEASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPP 401
P ++GHE + V G G +V + P C C C+ GR C +
Sbjct: 58 PAVLGHEINAEVVACGQDAALYQPGQQVVVIPYRHCGRCAACRRGRTTCCTALSVMGIHR 117
Query: 402 VHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPI 581
G + Y A D + + + AL+EP A+ HA +R GV+ G +LV+GAG I
Sbjct: 118 T-GAMQEYVTVAEDALLAVTG-IPHLQAALIEPYAIAAHAVRRSGVTHGVSLLVVGAGAI 175
Query: 582 GL 587
GL
Sbjct: 176 GL 177
>UniRef50_UPI00015BC9A2 Cluster: UPI00015BC9A2 related cluster; n=1;
unknown|Rep: UPI00015BC9A2 UniRef100 entry - unknown
Length = 335
Score = 93.5 bits (222), Expect = 3e-18
Identities = 57/167 (34%), Positives = 87/167 (52%), Gaps = 3/167 (1%)
Frame = +3
Query: 105 PIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGSKVKN 284
PIPEI DEVL+++ GIC SD+H G +V + P++ GHE +G+V K+GS VKN
Sbjct: 19 PIPEIGPDEVLIKVKYCGICHSDLHIVD-GDWESWV-KLPVVPGHEVAGIVEKVGSNVKN 76
Query: 285 LTVGDRVAIEPGV--PCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKL 458
+ GDRV + P + C C++C G LCP+ G Y K + F K+
Sbjct: 77 VKEGDRVGM-PWLYSSCEICDYCVEGEEPLCPNHEITGITR-QGGYAEYMKAPSHFVTKI 134
Query: 459 PDHVTMEEGALLEPLAVGIHAC-KRGGVSAGHVVLVLGAGPIGLLTM 596
PD + + A L + ++A R + +V++ G G +G L +
Sbjct: 135 PDKLELSYAAPLFCAGITVYAALVRLNLKPNELVVIQGIGGLGHLAI 181
>UniRef50_A4XEZ1 Cluster: Alcohol dehydrogenase, zinc-binding domain
protein; n=1; Novosphingobium aromaticivorans DSM
12444|Rep: Alcohol dehydrogenase, zinc-binding domain
protein - Novosphingobium aromaticivorans (strain DSM
12444)
Length = 347
Score = 93.5 bits (222), Expect = 3e-18
Identities = 59/180 (32%), Positives = 88/180 (48%), Gaps = 1/180 (0%)
Frame = +3
Query: 63 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHF-VLEEPMIMGH 239
A ++ P D+RL + P+P E L+++ G+CGSD+ Y +G G L P+ +GH
Sbjct: 10 ARVHGPGDVRLDEVPVPHCGPGEALVQVAACGVCGSDLGYIAQGGLGGVEPLSAPLPIGH 69
Query: 240 EASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLV 419
E +G V +G V ++ G RVA+ P + G PD A V G
Sbjct: 70 EFAGTVVAVGQCVTSVAPGMRVAVNPD-----RAYIGGGG----PDGAMAAFIRVAG--- 117
Query: 420 RYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLLTML 599
+ F LPDH+ E +L EPL+VG+H + G + +LGAGPIGL ++
Sbjct: 118 ---AEIGETLFPLPDHLPFAEASLAEPLSVGLHGLRVAGAKTEDRIAILGAGPIGLCALV 174
>UniRef50_A4FFG8 Cluster: Probable alcohol dehydrogenase; n=1;
Saccharopolyspora erythraea NRRL 2338|Rep: Probable
alcohol dehydrogenase - Saccharopolyspora erythraea
(strain NRRL 23338)
Length = 328
Score = 93.5 bits (222), Expect = 3e-18
Identities = 60/166 (36%), Positives = 86/166 (51%), Gaps = 1/166 (0%)
Frame = +3
Query: 105 PIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGSKVKN 284
P PE E +V++ M VG+CGSD+ + G+ + P I+GHE G + ++G V +
Sbjct: 19 PDPEPGEHDVVVEMLGVGLCGSDLSVYD-GKREPAAM--PWIIGHEGCGRIVEVGPAVTD 75
Query: 285 LTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDM-IFCATPPVHGNLVRYYKHAADFCFKLP 461
+VG+ V IEP C C++C+ GR C I P G L ++ A F + +P
Sbjct: 76 RSVGELVVIEPNYCCLLCQWCRRGRTAQCERRGIVGINRP--GLLSQFAAVPARFAWPVP 133
Query: 462 DHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLLTML 599
+ +E EPLAV +R GV AG LV+GAG GLL L
Sbjct: 134 EQWPVERLVCFEPLAVAQGVVRRSGVRAGESCLVVGAGSQGLLICL 179
>UniRef50_A2UF68 Cluster: Alcohol dehydrogenase GroES domain
protein; n=10; Proteobacteria|Rep: Alcohol dehydrogenase
GroES domain protein - Escherichia coli B
Length = 336
Score = 93.5 bits (222), Expect = 3e-18
Identities = 59/165 (35%), Positives = 83/165 (50%), Gaps = 1/165 (0%)
Frame = +3
Query: 96 VQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGSK 275
V+ P E+ EV + GICGSD+H KG GH + P++ GHE + V ++GS
Sbjct: 20 VEVPHQELKPHEVRIAPVFYGICGSDLHVL-KG--GHPFAKPPVVPGHEIAARVTEVGSD 76
Query: 276 VKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLC-PDMIFCATPPVHGNLVRYYKHAADFCF 452
VKN+ GD V ++P + C C CK GR++LC P + P G + A C
Sbjct: 77 VKNVQPGDHVVVDPIMACMECRACKAGRFNLCEPPQVAGFRAP--GFARSQHIVPARNCH 134
Query: 453 KLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGL 587
P + ++ A EP A H R ++ VLV+GAG IGL
Sbjct: 135 VAPASLPLKVLAFAEPAACARHCVNRMPKASLESVLVIGAGTIGL 179
>UniRef50_A0QZF0 Cluster: Oxidoreductase, zinc-binding dehydrogenase
family protein; n=3; Bacteria|Rep: Oxidoreductase,
zinc-binding dehydrogenase family protein -
Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
Length = 360
Score = 93.5 bits (222), Expect = 3e-18
Identities = 60/180 (33%), Positives = 83/180 (46%), Gaps = 7/180 (3%)
Frame = +3
Query: 69 LYKPNDLRLV--QTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEP----MI 230
+Y P D V Q + +VLL M GICGSD+ Y +G G+ ++ P ++
Sbjct: 13 VYLPGDSTAVLKQFDVRPPGPGQVLLEMGASGICGSDIGYIYRGYKGYRGIDGPAYQGVV 72
Query: 231 MGHEASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHG 410
GHE +G + G V VGDRV + V C C+ C+ G Y C G
Sbjct: 73 AGHEPAGRIVATGEGVTRFGVGDRVLLYHIVGCGLCDNCRRGFYISCSGDRASYGWQRDG 132
Query: 411 NLVRYYKHAADFCFKLPDHVTMEEGALLE-PLAVGIHACKRGGVSAGHVVLVLGAGPIGL 587
RY C LPD ++ +GAL+ A +R GVS H +LV+G GP+GL
Sbjct: 133 GHARYVLAEERTCIPLPDELSFVDGALIACGFATAYEGLRRAGVSGDHDLLVVGLGPVGL 192
>UniRef50_Q8EMM7 Cluster: Dehydrogenase; n=1; Oceanobacillus
iheyensis|Rep: Dehydrogenase - Oceanobacillus iheyensis
Length = 338
Score = 93.1 bits (221), Expect = 5e-18
Identities = 54/174 (31%), Positives = 86/174 (49%)
Frame = +3
Query: 78 PNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVV 257
P ++ P I++ +++ GICGSD+ + H E P++MGHE SG +
Sbjct: 9 PKNILFQNNRKPTITKGWAIIKTSYAGICGSDLSIFAGV---HPRAEAPLVMGHEFSGTI 65
Query: 258 AKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHA 437
+ +K G RV + P + C C C+ G H+C ++ G + Y K
Sbjct: 66 EEGHPTLKK---GTRVTVNPLLRCGECYPCQNGYSHVCENLKLVGID-CDGGMGEYVKVP 121
Query: 438 ADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLLTML 599
L D+++M+ GAL+EP+AV +HA ++G G V++ GAG IGL L
Sbjct: 122 IHSIVPLKDNISMKLGALIEPVAVAVHAIRQGNYMPGDSVVIFGAGTIGLCVAL 175
>UniRef50_Q5HLF5 Cluster: Sorbitol dehydrogenase, putative; n=10;
Bacilli|Rep: Sorbitol dehydrogenase, putative -
Staphylococcus epidermidis (strain ATCC 35984 / RP62A)
Length = 350
Score = 93.1 bits (221), Expect = 5e-18
Identities = 63/189 (33%), Positives = 90/189 (47%), Gaps = 10/189 (5%)
Frame = +3
Query: 63 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEE------- 221
A+ Y D+R+ I ++EV +++ GICG+D+H + +G F+ +
Sbjct: 4 AVWYGQKDVRVEDREPKAIKDNEVQVKVSWAGICGTDLHEYLEGPI--FISTDQPDPLLG 61
Query: 222 ---PMIMGHEASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCA 392
P+ +GHE SGVV +G V GDRV + P V R K L F
Sbjct: 62 QTAPVTLGHEFSGVVENVGKDVSRFKKGDRVVVNPTVSKRE----KPENVDLYDGYSFIG 117
Query: 393 TPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGA 572
G + + LPD+V+ EGAL+EP AV + A K G + G V V GA
Sbjct: 118 LGS-DGAFAEFTNAPETNVYHLPDNVSAREGALVEPTAVAVQAVKEGELLFGDTVAVFGA 176
Query: 573 GPIGLLTML 599
GPIGLLT++
Sbjct: 177 GPIGLLTIV 185
>UniRef50_A5FCD7 Cluster: Alcohol dehydrogenase, zinc-binding domain
protein; n=5; Bacteria|Rep: Alcohol dehydrogenase,
zinc-binding domain protein - Flavobacterium johnsoniae
UW101
Length = 356
Score = 93.1 bits (221), Expect = 5e-18
Identities = 56/171 (32%), Positives = 84/171 (49%)
Frame = +3
Query: 75 KPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGV 254
KP + +L + IPE E EVLL++ +GICG+D+H + G +F E P I+GHE +
Sbjct: 27 KPQEFKLKEKEIPEPKEGEVLLKIKRIGICGTDIHAFG-GTQPYF--EYPRILGHELAAE 83
Query: 255 VAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKH 434
K GD+V P C C C+ G + C ++ + G + Y
Sbjct: 84 YVK--GNAAGFKPGDKVTFIPYFNCGTCVACRNGLTNCCVNIKVFGVH-IDGGMAEYVSI 140
Query: 435 AADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGL 587
+ + +E AL+EPLA+ H +R V + VLV+GAGPIG+
Sbjct: 141 PEQYLLH-GQGLDYDELALVEPLAIAAHGVRRAAVKSTDTVLVMGAGPIGI 190
>UniRef50_A6M074 Cluster: Alcohol dehydrogenase GroES domain
protein; n=1; Clostridium beijerinckii NCIMB 8052|Rep:
Alcohol dehydrogenase GroES domain protein - Clostridium
beijerinckii NCIMB 8052
Length = 349
Score = 92.3 bits (219), Expect = 8e-18
Identities = 54/161 (33%), Positives = 92/161 (57%), Gaps = 3/161 (1%)
Frame = +3
Query: 117 ISEDEVLLRMDCVGICGSDVHYWQKGQCGHF-VLEEPMIMGHEASGVVAKIGSKVKNLTV 293
I+ ++V++ + GICG+DV G + V + + +GHE++G++A++GS+VKN+ V
Sbjct: 23 INPNDVIVDIKYCGICGTDVGII----AGTYPVAVKGVTLGHESTGIIAEVGSEVKNVKV 78
Query: 294 GDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVH-GNLVRYYKHAADFCFKLPDHV 470
GDRV I P C C C+T R + C + + + G Y+ +DF +K+PD V
Sbjct: 79 GDRVVINPTYYCGKCRMCQTLRINHCENKFGTESGVSYDGTYADRYRTTSDFVYKIPDGV 138
Query: 471 TMEEGALLEPLAVGIHACKRGGVSAGHV-VLVLGAGPIGLL 590
+M+ L EPL+ I ++ S+ ++ V GAG +G+L
Sbjct: 139 SMKAVTLTEPLSCVITGARKIQPSSMNLNTYVFGAGTMGIL 179
>UniRef50_A7RKY5 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 347
Score = 92.3 bits (219), Expect = 8e-18
Identities = 54/174 (31%), Positives = 91/174 (52%), Gaps = 4/174 (2%)
Frame = +3
Query: 87 LRLVQTPIPEISE-DEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAK 263
L ++ P+P +S EV++++ GIC D+ + G + +++GHE SGVV+
Sbjct: 12 LSVITRPVPHVSNPSEVIVKVAYSGICDRDLQILE----GELPAAKCVVLGHEFSGVVSD 67
Query: 264 IGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPV--HGNLVRYYKHA 437
+GS VKN+++GDRV + P C C+ C+ G+ H C + V +G +Y +
Sbjct: 68 VGSDVKNVSIGDRVVVNPNSSCNTCKACRRGQPHFCEKGGTGSAIGVWKNGGWTQYARVH 127
Query: 438 ADFCFKLPDHVTMEEGALLEPLAVGIHAC-KRGGVSAGHVVLVLGAGPIGLLTM 596
A +P V++++ AL EP++ +H K + +LV G G GLL M
Sbjct: 128 APNIHIVPPQVSLKQAALCEPISCVLHGLDKLHPAARDSKILVSGTGVTGLLWM 181
>UniRef50_Q63FG9 Cluster: Zinc-containing alcohol dehydrogenase;
possible sorbitol dehydrogenase; n=3; Bacillus
cereus|Rep: Zinc-containing alcohol dehydrogenase;
possible sorbitol dehydrogenase - Bacillus cereus
(strain ZK / E33L)
Length = 340
Score = 91.9 bits (218), Expect = 1e-17
Identities = 55/179 (30%), Positives = 91/179 (50%)
Frame = +3
Query: 63 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 242
A+ Y D+R+ + E+ ++V +++ GICGSD+H + + + ++GHE
Sbjct: 4 AVWYGEKDIRIEERETKELQPNDVKVKVAWAGICGSDLHAYLHPDS--VPMNKNTVLGHE 61
Query: 243 ASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVR 422
SG + ++GS V GDRV I P + + +T R+ + D + + G
Sbjct: 62 FSGEIVEVGSHVTKFKEGDRVCIYP-MMLKDPSNAETERF-ITLDAVGAQ---IDGGFAE 116
Query: 423 YYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLLTML 599
Y FK+PD++++E A++EP AV + K V G V+V GAGPIGL +L
Sbjct: 117 YVILPQKTIFKIPDNLSLEVAAMVEPAAVSFQSIKDSNVEEGDTVVVYGAGPIGLFAVL 175
>UniRef50_Q46N56 Cluster: Zinc-containing alcohol dehydrogenase
superfamily; n=2; Burkholderiales|Rep: Zinc-containing
alcohol dehydrogenase superfamily - Ralstonia eutropha
(strain JMP134) (Alcaligenes eutrophus)
Length = 337
Score = 91.9 bits (218), Expect = 1e-17
Identities = 59/188 (31%), Positives = 95/188 (50%), Gaps = 9/188 (4%)
Frame = +3
Query: 57 LTALLY-KPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEP-MI 230
+ A++Y +P+ + ++ +P++ E+LLR+D GICGSD+H + GH +P ++
Sbjct: 1 MKAIVYTQPDAVEVLDRDMPDLEPGEILLRIDASGICGSDLHAYH----GHDPRRKPGLV 56
Query: 231 MGHEASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPD--MIFCATPPV 404
+GHE +G V + + + VG RV P V C +C++C GR +LC + M+ P
Sbjct: 57 LGHEFAGTVIASSDEAR-MPVGQRVTANPLVTCGHCDYCLQGRDNLCANRGMVGMNRP-- 113
Query: 405 HGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGH-----VVLVLG 569
G L Y +PD + AL EP A +HA + VL++G
Sbjct: 114 -GALSEYLAIPIRCAIPIPDTLPSVSAALTEPAATALHAVNLTMRAMSRPLPEVSVLIIG 172
Query: 570 AGPIGLLT 593
G IG+LT
Sbjct: 173 GGAIGMLT 180
>UniRef50_A1SLI2 Cluster: Alcohol dehydrogenase GroES domain
protein; n=6; Actinomycetales|Rep: Alcohol dehydrogenase
GroES domain protein - Nocardioides sp. (strain BAA-499
/ JS614)
Length = 352
Score = 91.9 bits (218), Expect = 1e-17
Identities = 60/182 (32%), Positives = 85/182 (46%), Gaps = 9/182 (4%)
Frame = +3
Query: 72 YKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASG 251
Y P D+RL + P P DEV LR+ CG+DV G H L P +GHE +G
Sbjct: 7 YAPEDVRLEEVPEPTCGPDEVKLRVRNCSTCGTDVKILHNG---HQNLTPPRTIGHEIAG 63
Query: 252 VVAKIGSKVK-----NLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHG-- 410
V ++G+ V + GDRV + VPC C C+ G +C + G
Sbjct: 64 EVVEVGADVNVTYGSSWAAGDRVQVIAAVPCGECYECQKGWMAVCQNQTSMGYQYDGGFA 123
Query: 411 --NLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIG 584
+V D ++PD+V +E + EP A I+A + G+ G V+V GAGPIG
Sbjct: 124 EYMIVPRQVLKVDGLNRIPDNVGYDEASAAEPFACAINAQELLGIEPGDTVVVFGAGPIG 183
Query: 585 LL 590
+
Sbjct: 184 CM 185
>UniRef50_A3H8A1 Cluster: Alcohol dehydrogenase GroES-like; n=1;
Caldivirga maquilingensis IC-167|Rep: Alcohol
dehydrogenase GroES-like - Caldivirga maquilingensis
IC-167
Length = 337
Score = 91.9 bits (218), Expect = 1e-17
Identities = 59/172 (34%), Positives = 88/172 (51%), Gaps = 1/172 (0%)
Frame = +3
Query: 84 DLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEE-PMIMGHEASGVVA 260
+++ V PIP+ V++R+ G+CGSD+ G G L P+IMGHE +G+V
Sbjct: 13 EIKDVPKPIPQ--PGWVVMRVKYTGVCGSDI----GGFLGKNELRRPPLIMGHEFTGIVE 66
Query: 261 KIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAA 440
+ G V +G + P + C +C +C++G +LC M G Y
Sbjct: 67 EAGPGVPKEYIGRLFTVNPIIGCGHCRYCRSGLKNLCV-MRKIIGIDYPGAYAEYVAVPV 125
Query: 441 DFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLLTM 596
D + + D V +GAL EPLA + A + GVS G VLV+GAGP+G L +
Sbjct: 126 DNLYPVSDPV---KGALAEPLATSLRAVRLSGVSLGDSVLVIGAGPVGSLAI 174
>UniRef50_Q6NDJ8 Cluster: Putative Zn-binding dehydrogenase; n=1;
Rhodopseudomonas palustris|Rep: Putative Zn-binding
dehydrogenase - Rhodopseudomonas palustris
Length = 346
Score = 91.5 bits (217), Expect = 1e-17
Identities = 64/187 (34%), Positives = 94/187 (50%), Gaps = 6/187 (3%)
Frame = +3
Query: 57 LTALLYKPNDLRLVQTPI--PEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMI 230
+ A +++ RLV + P + ++E+LL++ GICGSD+H + +L+ +
Sbjct: 1 MKAAVFEKTGERLVVRDVAAPALGDNELLLKVAFTGICGSDLHAAETPG----MLQSGTV 56
Query: 231 MGHEASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEF---CKTGRYHLCPDMIFCA-TP 398
MGHE +G + + S + VG RVA P C C C G C + F P
Sbjct: 57 MGHEFTGEIVQ--STASDWPVGARVAANPYWLCDACAAGGSCSGGGDAACANGSFMGFRP 114
Query: 399 PVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGP 578
+ G Y + A +LPD V++ +GAL+EPLAV HA G G VLV+G GP
Sbjct: 115 DLPGAYADYVRIRAGQAIRLPDKVSLRDGALMEPLAVARHAVDVCGPMQGADVLVIGGGP 174
Query: 579 IGLLTML 599
IGL +L
Sbjct: 175 IGLGVVL 181
>UniRef50_Q0LSY1 Cluster: Alcohol dehydrogenase,
zinc-binding:Alcohol dehydrogenase GroES-like; n=2;
Alphaproteobacteria|Rep: Alcohol dehydrogenase,
zinc-binding:Alcohol dehydrogenase GroES-like -
Caulobacter sp. K31
Length = 364
Score = 91.5 bits (217), Expect = 1e-17
Identities = 58/185 (31%), Positives = 85/185 (45%), Gaps = 11/185 (5%)
Frame = +3
Query: 78 PNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVV 257
P L + PIP+I D +LR++ GICGSD ++ G P+I GHE G++
Sbjct: 14 PRTLEMRDLPIPDIEADSAILRIEACGICGSDYEQFE----GVLKTPMPVIPGHEPVGII 69
Query: 258 AKIGSKVKN---LTVGDRVAIEPGVPCRYCEFCKTGRYHLCPD------MIFCATPPVHG 410
IG K + VGDRVA+E + C C+ C GRYHLC D + P + G
Sbjct: 70 EAIGDKAARRWGVDVGDRVAVETMLSCHSCDTCLGGRYHLCADRQIYSYIPLSNMPGLWG 129
Query: 411 NLVRY-YKHAADFCFKLPDHVTMEEGALLEPLAVGIH-ACKRGGVSAGHVVLVLGAGPIG 584
+Y Y K+ + E + PL G A + G +++LG G G
Sbjct: 130 AYAQYMYLAPNTIVHKMDKTLPPELAVMFNPLGAGFRWAVEIPQTQVGDTIVILGPGQRG 189
Query: 585 LLTML 599
L +++
Sbjct: 190 LASVI 194
>UniRef50_Q7N973 Cluster: Similarities with different types of
deshydrogenases; n=1; Photorhabdus luminescens subsp.
laumondii|Rep: Similarities with different types of
deshydrogenases - Photorhabdus luminescens subsp.
laumondii
Length = 353
Score = 91.1 bits (216), Expect = 2e-17
Identities = 54/165 (32%), Positives = 82/165 (49%), Gaps = 3/165 (1%)
Frame = +3
Query: 105 PIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEP-MIMGHEASGVVAKIGSKVK 281
P+ D+V++ + G+CG+DV G + + P +GHE +GV+ +IG V
Sbjct: 19 PLRCAEPDDVVVDIAVCGVCGTDVGIIT----GSYPVAIPGTTLGHETTGVITQIGKSVT 74
Query: 282 NLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFC-ATPPVHGNLVRYYKHAADFCFKL 458
VGDRV I P C +C C+TG + C + A G Y KL
Sbjct: 75 RFNVGDRVVINPTYSCGHCRMCQTGSPNHCEKKLGTEAGVSYDGAFAEQYLAKESSLIKL 134
Query: 459 PDHVTMEEGALLEPLAVGIHACKRGGVSAGHV-VLVLGAGPIGLL 590
DHV+MEE +L EPL+ + + G++ ++ V GAGP+G+L
Sbjct: 135 DDHVSMEEASLTEPLSCTLTGVDKLGITHTNIRAAVAGAGPMGML 179
>UniRef50_Q2LQ73 Cluster: Zinc-binding dehydrogenase; n=2;
Bacteria|Rep: Zinc-binding dehydrogenase - Syntrophus
aciditrophicus (strain SB)
Length = 362
Score = 91.1 bits (216), Expect = 2e-17
Identities = 60/189 (31%), Positives = 91/189 (48%), Gaps = 7/189 (3%)
Frame = +3
Query: 51 DNLTALLYK-PNDLRLVQTPIPEISE-DEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEP 224
D + A++Y+ P L P P I E D+V+ R+ I GSDV G + P
Sbjct: 12 DTMKAMVYRGPGRYGLEDVPAPVILEPDDVIGRVTLSSISGSDVQIVHGGLPE---VRTP 68
Query: 225 MIMGHEASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDM---IFCAT 395
+I+GHE + ++G VK+L VGDRV + C C C+ G + C F
Sbjct: 69 LIVGHEFCAEIMEVGPAVKSLNVGDRVVVSCVAFCGECRSCRQGLHARCEKTGFGSFGMN 128
Query: 396 PPVHGNLVRYYKHAAD-FCFKLPDHVTMEEGALL-EPLAVGIHACKRGGVSAGHVVLVLG 569
P G AD +CFK+P+ +T ++ + L+ G + + G + G V+V+G
Sbjct: 129 GPDGGQAEYVRLPGADRYCFKIPESLTFQDVLFCGDVLSAGYYGAEMGDIQRGETVVVVG 188
Query: 570 AGPIGLLTM 596
AGP+GL M
Sbjct: 189 AGPVGLCAM 197
>UniRef50_Q5BFT1 Cluster: Putative uncharacterized protein; n=1;
Emericella nidulans|Rep: Putative uncharacterized
protein - Emericella nidulans (Aspergillus nidulans)
Length = 391
Score = 91.1 bits (216), Expect = 2e-17
Identities = 68/218 (31%), Positives = 99/218 (45%), Gaps = 35/218 (16%)
Frame = +3
Query: 39 DMATDNLTALLYK------PNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQC 200
++ATDN L K P D+R+ Q P + +V LR GICGSD+H + G
Sbjct: 6 EIATDNENMPLMKALQFHGPRDVRVEQIEEPVCGKGQVKLRNTYCGICGSDLHEYTSGPV 65
Query: 201 -----GHFVLEE--PMIMGHEASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGR 359
H + + P++MGHE GVV ++G + +L G + + P + R C CK G
Sbjct: 66 LIPKGAHSITKATAPVVMGHEFGGVVEEVGEGITHLKPGQKAVVRPTIFDRKCPPCKIGY 125
Query: 360 YHLCPDMIFC------------------ATPPVH----GNLVRYYKHAADFCFKLPDHVT 473
+ C ++ F A P+ G A+ + +PD+VT
Sbjct: 126 EYCCENIGFIGLSGMLFFRIKQAVRSGQANVPMRTGYGGGFAEKIVAPAEHFYPIPDNVT 185
Query: 474 MEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGL 587
E A++EPLAV HA G VLV+G GP+GL
Sbjct: 186 PESMAMIEPLAVAWHAVNLSPFKEGDNVLVVGGGPLGL 223
>UniRef50_Q0TXS2 Cluster: Putative uncharacterized protein; n=2;
Pezizomycotina|Rep: Putative uncharacterized protein -
Phaeosphaeria nodorum (Septoria nodorum)
Length = 359
Score = 91.1 bits (216), Expect = 2e-17
Identities = 61/176 (34%), Positives = 83/176 (47%), Gaps = 3/176 (1%)
Frame = +3
Query: 81 NDLRLVQTPIPEISEDEVLLRMDCVG---ICGSDVHYWQKGQCGHFVLEEPMIMGHEASG 251
NDLR + PIPE +V ++ +G +C + H G V P+ GHE SG
Sbjct: 26 NDLRYEKIPIPEAKAGQVKVKPAYLGGPNLCPTTPH----PITGESV---PLTFGHEFSG 78
Query: 252 VVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYK 431
V +G V GDRV ++P + C C+ G + C F G L +
Sbjct: 79 TVETVGQGVTAYKPGDRVVVQPIIYDGTCGACEEGLQNCCWQNGFVGLSGWGGGLADHIV 138
Query: 432 HAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLLTML 599
+ LPD+V +E GAL+EPLAVG HA K L+LG GPIG+ T+L
Sbjct: 139 VPESTLYHLPDNVPLEIGALVEPLAVGWHAVKVSPFKKDDTALILGGGPIGISTIL 194
>UniRef50_Q7D7T9 Cluster: Zinc-binding dehydrogenase; n=15;
Mycobacterium|Rep: Zinc-binding dehydrogenase -
Mycobacterium tuberculosis
Length = 384
Score = 90.6 bits (215), Expect = 2e-17
Identities = 58/175 (33%), Positives = 89/175 (50%), Gaps = 5/175 (2%)
Frame = +3
Query: 87 LRLVQTPIPEI-SEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAK 263
+R+ P P + D V++ + GICGSD+H+++ G + EP+ +GHEA G + +
Sbjct: 12 VRVNTQPDPALPGPDGVVVAVTAAGICGSDLHFYE----GEYPFTEPVALGHEAVGTIVE 67
Query: 264 IGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLC--PDMIFCATPPVHGNLVRYYKHA 437
G +V+ + VGD V + C C C+T +C MIF A A
Sbjct: 68 AGPQVRTVGVGDLVMVSSVAGCGVCPGCETHDPVMCFSGPMIFGAGVLGGAQADLLAVPA 127
Query: 438 ADF-CFKLPDHVTMEEGALL-EPLAVGIHACKRGGVSAGHVVLVLGAGPIGLLTM 596
ADF K+P+ +T E+ LL + LA G A +R +S G V V+G G +GL +
Sbjct: 128 ADFQVLKIPEGITTEQALLLTDNLATGWAAAQRADISFGSAVAVIGLGAVGLCAL 182
>UniRef50_Q0FV22 Cluster: Sorbitol dehydrogenase; n=1; Roseovarius
sp. HTCC2601|Rep: Sorbitol dehydrogenase - Roseovarius
sp. HTCC2601
Length = 351
Score = 90.6 bits (215), Expect = 2e-17
Identities = 55/161 (34%), Positives = 72/161 (44%), Gaps = 2/161 (1%)
Frame = +3
Query: 111 PEISEDEVLLRMDCVGICGSDVHY--WQKGQCGHFVLEEPMIMGHEASGVVAKIGSKVKN 284
P EV + + GICGSD+H W G P+ +GHE +G V G V
Sbjct: 23 PGPGRGEVEVAVQAAGICGSDLHAVAWDPSY-GFMEPLLPLTLGHEFAGTVTATGEGVSR 81
Query: 285 LTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPD 464
+ GDRV P + C CE C+ GR C G + +LP
Sbjct: 82 VVTGDRVVCSPTLTCGRCEGCRQGRPSACEARQIVGLHR-DGGFAERVRVPESVLHRLPA 140
Query: 465 HVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGL 587
+ E AL EPL++ ++A V+AG VLVLG GPIGL
Sbjct: 141 AIGFERAALAEPLSIAVNAVNVAEVAAGDRVLVLGPGPIGL 181
>UniRef50_A4XUM5 Cluster: Alcohol dehydrogenase GroES domain
protein; n=2; Pseudomonas|Rep: Alcohol dehydrogenase
GroES domain protein - Pseudomonas mendocina ymp
Length = 422
Score = 90.6 bits (215), Expect = 2e-17
Identities = 56/184 (30%), Positives = 90/184 (48%), Gaps = 17/184 (9%)
Frame = +3
Query: 84 DLRLVQTPIPEI-SEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVA 260
D+RL + P P++ + + ++R+ ICG+D+H+ +G G + + I+GHEA G+V
Sbjct: 11 DIRLDEVPEPQVQASTDAVIRITASAICGTDLHF-VRGTVGG--MRKGTILGHEAVGIVE 67
Query: 261 KIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPD---------MIFCATPPVHGN 413
+GS V+NL++GDRV + + C C +C+ G Y C + F P + G
Sbjct: 68 ALGSDVRNLSIGDRVVVPSTIACGNCAYCRAGYYAQCDEANPNGKEAGTSFYGGPEITGA 127
Query: 414 LVRYYKHAADFCF------KLPDHVTMEEGALLEPL-AVGIHACKRGGVSAGHVVLVLGA 572
A F KLP ++ ++ LL + G K VS+G V V G
Sbjct: 128 FDGLQAELARIPFANIGLVKLPSEISDDQAILLSDIFPTGYFGAKLAEVSSGDTVAVFGC 187
Query: 573 GPIG 584
GP+G
Sbjct: 188 GPVG 191
>UniRef50_A0JVZ1 Cluster: Alcohol dehydrogenase GroES domain
protein; n=1; Arthrobacter sp. FB24|Rep: Alcohol
dehydrogenase GroES domain protein - Arthrobacter sp.
(strain FB24)
Length = 344
Score = 90.6 bits (215), Expect = 2e-17
Identities = 64/190 (33%), Positives = 89/190 (46%), Gaps = 7/190 (3%)
Frame = +3
Query: 48 TDNLTALLYKPND-LRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEP 224
T + AL + D + +V +PE E++L + G+CGSD+HY+ +P
Sbjct: 2 TTTVRALRFAEKDRVSVVDAALPEAGPGEIVLDVKAAGLCGSDLHYFHMTHNQMQNATQP 61
Query: 225 ----MIMGHEASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPD-MIFC 389
M GHE +GVVA IG V + +VGDRVAI+ C CE C+ G C + ++
Sbjct: 62 RSPEMTPGHEIAGVVASIGPGVTHPSVGDRVAIQHYSGCGTCETCRKGWDVHCENARVYS 121
Query: 390 ATPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLE-PLAVGIHACKRGGVSAGHVVLVL 566
P G A LPD V+ GA L A +R V G VLV+
Sbjct: 122 LNRP--GGCQDQVIVTAKDAVVLPDSVSFATGAFLACGATTAYQAIQRSEVRPGGTVLVI 179
Query: 567 GAGPIGLLTM 596
GAGP+GL +
Sbjct: 180 GAGPVGLAVL 189
>UniRef50_Q67N85 Cluster: L-threonine 3-dehydrogenase; n=10;
Bacteria|Rep: L-threonine 3-dehydrogenase -
Symbiobacterium thermophilum
Length = 351
Score = 90.6 bits (215), Expect = 2e-17
Identities = 51/170 (30%), Positives = 79/170 (46%), Gaps = 2/170 (1%)
Frame = +3
Query: 93 LVQTPIPEISEDEVLLRMDCVGICGSDVHY--WQKGQCGHFVLEEPMIMGHEASGVVAKI 266
L + PIP I +VL+++ ICG+D H W G ++ P+ +GHE +G V +
Sbjct: 19 LQEVPIPTIGPRDVLVKVRAASICGTDYHIYTWDPWSAGR--VKPPLTIGHELAGEVVAV 76
Query: 267 GSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADF 446
G +V VGD V+ E + C C C G YHLC + G Y
Sbjct: 77 GREVTACKVGDYVSAETHIVCNRCPRCHMGEYHLCENTKILGV-DTDGAFAEYVAVPEQN 135
Query: 447 CFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLLTM 596
+ + E ++ EPL +H G ++A VL+ G GPIG++++
Sbjct: 136 IWVNDKDIPFELQSIQEPLGNAVHTALNGDLTA-RSVLITGCGPIGIMSV 184
>UniRef50_A5V2Z1 Cluster: Alcohol dehydrogenase, zinc-binding domain
protein; n=1; Sphingomonas wittichii RW1|Rep: Alcohol
dehydrogenase, zinc-binding domain protein -
Sphingomonas wittichii RW1
Length = 337
Score = 90.2 bits (214), Expect = 3e-17
Identities = 57/167 (34%), Positives = 78/167 (46%)
Frame = +3
Query: 87 LRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKI 266
+ + P PE E ++++ GICGSD+ H +GHE +G V +
Sbjct: 13 MTIEDVPDPEPGPGEAVIKVCRCGICGSDIGMTSGS---HADYPAGTTLGHEYAGEVVAV 69
Query: 267 GSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADF 446
G V NL VG RV+ P C C C G C M + G +Y + A
Sbjct: 70 GRDVSNLKVGQRVSAMPAKGCGRCASCLAGFPLGCTAMA-----GMIGGFGQYMRIYAPA 124
Query: 447 CFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGL 587
LPD ++M +GAL+EPLAVG+ G+ G V VLGAG +GL
Sbjct: 125 AIHLPDTLSMADGALVEPLAVGLRGVALAGLRPGATVAVLGAGAVGL 171
>UniRef50_Q7U377 Cluster: Putative Zinc-binding dehydrogenase; n=2;
Bordetella|Rep: Putative Zinc-binding dehydrogenase -
Bordetella parapertussis
Length = 360
Score = 89.8 bits (213), Expect = 4e-17
Identities = 58/186 (31%), Positives = 85/186 (45%), Gaps = 12/186 (6%)
Frame = +3
Query: 78 PNDLRLVQTPIPEI-SEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGV 254
P L VQ P+PE+ + DE L+R++ GICG+D ++ G GH +I GHE G
Sbjct: 11 PRRLEYVQLPLPEVLAPDEALVRVEGCGICGTDYERYE-GSLGHV---PELIPGHEPVGR 66
Query: 255 VAKIGSKVKN---LTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVH------ 407
+ +IG L GDRVA++P C C +C G + LC I P+
Sbjct: 67 IERIGDSAAQRMQLKEGDRVAVQPHYGCGVCSYCVEGMFQLCARKINLGLSPLSEGCGLW 126
Query: 408 GNLVRYYKHAAD-FCFKLPDHVTMEEGALLEPLAVGIH-ACKRGGVSAGHVVLVLGAGPI 581
G + + K+PD + +E+ + PL G A G G VL+ G G
Sbjct: 127 GGFAEHMMLKGNAIVHKMPDSLPIEDAVMFNPLGAGFEWAITSAGTRVGDDVLIFGPGQR 186
Query: 582 GLLTML 599
GL ++
Sbjct: 187 GLACVI 192
>UniRef50_Q24T43 Cluster: Putative uncharacterized protein; n=1;
Desulfitobacterium hafniense Y51|Rep: Putative
uncharacterized protein - Desulfitobacterium hafniense
(strain Y51)
Length = 319
Score = 89.8 bits (213), Expect = 4e-17
Identities = 57/175 (32%), Positives = 86/175 (49%)
Frame = +3
Query: 66 LLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEA 245
+L+ +DLRL + +P +S EVL+R+ C GIC SDV H+ P+I+GHE
Sbjct: 11 VLHNIDDLRLSEVKLPVLSRGEVLVRVKCAGICSSDVQRVFVSGAYHY----PIILGHEF 66
Query: 246 SGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRY 425
SG+V K S + +G RV + P +P E +T Y D + + G Y
Sbjct: 67 SGIVEKAYSDAEASWIGKRVGVYPLLPKFANEGYRTDGYETSSDYGYLGSRQ-DGGFAEY 125
Query: 426 YKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLL 590
++P+ + EE A+LEP +V HA ++ + V V+G G IG L
Sbjct: 126 VAVPVWNLIEIPEKIGFEEAAMLEPTSVAFHAVRQIDFTHVRNVAVIGNGTIGHL 180
>UniRef50_A0QS68 Cluster: 2-deoxy-scyllo-inosamine dehydrogenase;
n=1; Mycobacterium smegmatis str. MC2 155|Rep:
2-deoxy-scyllo-inosamine dehydrogenase - Mycobacterium
smegmatis (strain ATCC 700084 / mc(2)155)
Length = 341
Score = 89.8 bits (213), Expect = 4e-17
Identities = 56/179 (31%), Positives = 83/179 (46%), Gaps = 1/179 (0%)
Frame = +3
Query: 57 LTALLYK-PNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIM 233
+ A+LY+ P + P P+ + EV +R+ VG+CG+D+H G F P+I
Sbjct: 1 MKAVLYEAPKTWSVTDVPTPQPGKGEVRIRVAQVGVCGTDLHIHD----GEFGAVFPLIP 56
Query: 234 GHEASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGN 413
GHE GVV +G V +G++V + P V C C +C GR C M+ + G
Sbjct: 57 GHELVGVVDAVGEGVTRFGIGEQVTVNPNVYCGQCPYCLAGRLGQCAAMLGYGS-NFPGF 115
Query: 414 LVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLL 590
Y F + + ++ EP A +H + + G LVLGAGP GLL
Sbjct: 116 FAEYAIADHTLVFS-TEGLPLDTAVFSEPTACAMHGLESLQMRPGGSALVLGAGPTGLL 173
>UniRef50_Q0RVL1 Cluster: Zn-dependent alcohol dehydrogenase; n=1;
Rhodococcus sp. RHA1|Rep: Zn-dependent alcohol
dehydrogenase - Rhodococcus sp. (strain RHA1)
Length = 347
Score = 88.6 bits (210), Expect = 1e-16
Identities = 57/181 (31%), Positives = 85/181 (46%), Gaps = 5/181 (2%)
Frame = +3
Query: 63 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 242
A+ +P + + P P+ +VLLR VGICGSD+H ++KG G IMGHE
Sbjct: 4 AVYQRPGLIEVQDVPTPQPGPRDVLLRTRAVGICGSDLHVYRKGLYG---ATTGWIMGHE 60
Query: 243 ASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCAT----PPVHG 410
G ++G +V+ +VG+R C C +C+ + LCP + T P
Sbjct: 61 FCGEAVEVGEEVRGASVGERYTGFSVEFCGQCYWCQRNQQRLCPHLFEHYTGYGEPGAMA 120
Query: 411 NLVRYYKHAAD-FCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGL 587
V + D F +P ++ E AL EPL ++ +R G V+V+G G IG
Sbjct: 121 EYVLIRQAQLDQNLFAIPASLSDEAAALAEPLGTAAYSVRRAKPQDGDTVVVIGGGMIGN 180
Query: 588 L 590
L
Sbjct: 181 L 181
>UniRef50_A3H9A2 Cluster: Alcohol dehydrogenase GroES-like; n=1;
Caldivirga maquilingensis IC-167|Rep: Alcohol
dehydrogenase GroES-like - Caldivirga maquilingensis
IC-167
Length = 360
Score = 88.6 bits (210), Expect = 1e-16
Identities = 53/166 (31%), Positives = 82/166 (49%), Gaps = 2/166 (1%)
Frame = +3
Query: 108 IPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKIGSK--VK 281
I E VL+R VG+CG+D + + G ++ P+++GHE V I +
Sbjct: 17 IKEAPPRHVLIRPLLVGVCGTDKEICRGHREG---IKYPLVIGHEIVAQVVNIAEEDGSN 73
Query: 282 NLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLP 461
+L + DRV + P C C CK G ++ C + + G L Y + + FK+P
Sbjct: 74 SLKINDRVVVFPNYWCDSCIDCKVGHFNTCKNKVSIGVN-APGALSEYMDVESKYLFKVP 132
Query: 462 DHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLLTML 599
D ++ E L EPLAV IHA K+ G +L++G G +G LT +
Sbjct: 133 DSLSNYEAVLTEPLAVVIHAMKKIDPKPGDNILIIGGGALGHLTTM 178
>UniRef50_Q0CVZ1 Cluster: Putative uncharacterized protein; n=1;
Aspergillus terreus NIH2624|Rep: Putative
uncharacterized protein - Aspergillus terreus (strain
NIH 2624)
Length = 386
Score = 88.2 bits (209), Expect = 1e-16
Identities = 59/180 (32%), Positives = 85/180 (47%)
Frame = +3
Query: 54 NLTALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIM 233
N + +L + + + P+P + D VL+++ GICGSD+H + G G +M
Sbjct: 23 NTSCVLVEKRRISIEPIPMPILQPDGVLVKVIANGICGSDMHVYLSGGIGGRGAYGRTVM 82
Query: 234 GHEASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGN 413
GHEA+G V +G V GDRVA+ + C G L M F A P
Sbjct: 83 GHEAAGEVIAVGEHVTTHKPGDRVAVISVLMCAIAVL--RGTMDLSRGMFF-ALP----- 134
Query: 414 LVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLLT 593
AD +P+ V+ EE ++PLA+GI KR + A V + G GPIGL+T
Sbjct: 135 --------ADMAPHIPETVSWEEAGSIQPLAIGIQIGKRADLRAHQTVAIFGCGPIGLIT 186
>UniRef50_A0LGB6 Cluster: Alcohol dehydrogenase GroES domain
protein; n=1; Syntrophobacter fumaroxidans MPOB|Rep:
Alcohol dehydrogenase GroES domain protein -
Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB)
Length = 321
Score = 87.8 bits (208), Expect = 2e-16
Identities = 59/178 (33%), Positives = 79/178 (44%)
Frame = +3
Query: 66 LLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEA 245
+L P L+L +PE E LLR+ +C +D W +G H L P I+GHE
Sbjct: 5 VLESPGVLKLTDMQVPEPEPHERLLRVTHCAVCRTDAKMWSQG---HRDLRLPRILGHEV 61
Query: 246 SGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRY 425
VV S R + PG C CE+C+ G +LC M HG Y
Sbjct: 62 C-VVPSDSS--------GRFVVWPGTACGTCEYCRKGFENLCSAMEILGFHR-HGGFAEY 111
Query: 426 YKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLLTML 599
AD +P + L EPLA ++A R G + G +L+ GAGP+GLL L
Sbjct: 112 LAAPADSLVPVPPELPGAIACLAEPLACTLNALDRVGAAPGERLLIYGAGPVGLLMAL 169
>UniRef50_Q5A958 Cluster: Potential secondary alcohol dehydrogenase;
n=8; Saccharomycetales|Rep: Potential secondary alcohol
dehydrogenase - Candida albicans (Yeast)
Length = 359
Score = 87.8 bits (208), Expect = 2e-16
Identities = 54/165 (32%), Positives = 86/165 (52%), Gaps = 5/165 (3%)
Frame = +3
Query: 105 PIPEISEDEVLLRMDCVGICGSDVHYWQKG-QCGHFVLEEPMIMGHEASGVVAKIGSKVK 281
P+ + ++LL++D VG+C SD+H +G CG + +MGHE +G VA++G +V
Sbjct: 48 PVNKPGAGQLLLKVDAVGLCHSDLHVLYEGLDCG-----DNYVMGHEIAGTVAELGEEVS 102
Query: 282 NLTVGDRVAIEPGVPCRYCEFCKTGRYHLC-PDMIFCATPPVHGNLVRY--YKHAADFCF 452
VGDRVA C C+ C TG ++C + +G ++ K +
Sbjct: 103 EFAVGDRVACVGPNGCGLCKHCLTGNDNVCTKSFLDWFGLGYNGGYEQFLLVKRPRNL-V 161
Query: 453 KLPDHVTMEE-GALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIG 584
K+PD+VT EE A+ + + HA K GV +L++GAG +G
Sbjct: 162 KIPDNVTSEEAAAITDAVLTPYHAIKSAGVGPASNILIIGAGGLG 206
>UniRef50_A2QFZ8 Cluster: Catalytic activity: alcohol dehydrogenase
I; n=1; Aspergillus niger|Rep: Catalytic activity:
alcohol dehydrogenase I - Aspergillus niger
Length = 340
Score = 87.8 bits (208), Expect = 2e-16
Identities = 55/165 (33%), Positives = 82/165 (49%), Gaps = 2/165 (1%)
Frame = +3
Query: 87 LRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKI 266
+ L Q P+ DEVL++M+ G+C +D+H W KG GHE G+VA +
Sbjct: 25 IELKQIPVGNPGPDEVLVQMEYSGVCHTDLHAW-KG-------------GHEGVGLVAAV 70
Query: 267 GSKVKNLTVGDRVAIE-PGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAAD 443
GS+V L +GD V I+ C CEFC TGR LCP + V G +Y AD
Sbjct: 71 GSQVNGLRIGDTVGIQWINRTCGVCEFCSTGRQPLCPKLQLSGY-MVDGTFQQYCICKAD 129
Query: 444 FCFKLPDHVTMEEGALLEPLAVGIH-ACKRGGVSAGHVVLVLGAG 575
++P +++E A + ++ A K V G ++ ++GAG
Sbjct: 130 NAVRIPSGISLEAAAPVLCAGTTVYKALKESEVQPGQIIAIVGAG 174
>UniRef50_Q9P6I8 Cluster: Glutathione-dependent formaldehyde
dehydrogenase; n=1; Schizosaccharomyces pombe|Rep:
Glutathione-dependent formaldehyde dehydrogenase -
Schizosaccharomyces pombe (Fission yeast)
Length = 423
Score = 87.0 bits (206), Expect = 3e-16
Identities = 62/194 (31%), Positives = 88/194 (45%), Gaps = 24/194 (12%)
Frame = +3
Query: 78 PNDLRLVQTPIPEISED-EVLLRMDCVGIC-GSDVHYWQKGQCGHFVLEEPMIMGHEASG 251
P ++++ + P P I+ +V+++ IC GSD H + G +E+ I+GHE+ G
Sbjct: 45 PLNVKIAEVPKPTITHPKDVIVKTTACTICSGSDSHIFSGEMPG---IEKGAILGHESCG 101
Query: 252 VVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPV-----HGNL 416
+VA+ G +V NL +GDRV I + C C FCK Y C V H +
Sbjct: 102 IVAEKGDEVNNLEIGDRVVIAFDLACGQCSFCKRHEYAACDTTNDSKLMDVNYGSHHSAI 161
Query: 417 VRYYKHAADF----------------CFKLPDHVTMEEGALL-EPLAVGIHACKRGGVSA 545
Y K D C KLPD + EG + + L +HAC G V
Sbjct: 162 FGYTKLLGDVPGCQAEYIRVPFAEINCCKLPDDIPDSEGLFMSDVLCTSLHACTLGEVKK 221
Query: 546 GHVVLVLGAGPIGL 587
G V + G GPIGL
Sbjct: 222 GDTVAIWGMGPIGL 235
>UniRef50_A3DME0 Cluster: Alcohol dehydrogenase GroES domain
protein; n=1; Staphylothermus marinus F1|Rep: Alcohol
dehydrogenase GroES domain protein - Staphylothermus
marinus (strain ATCC 43588 / DSM 3639 / F1)
Length = 333
Score = 87.0 bits (206), Expect = 3e-16
Identities = 54/177 (30%), Positives = 88/177 (49%)
Frame = +3
Query: 66 LLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEA 245
+L+ P DLRL + P D V +R+ +GICG+D ++ KG + ++++P+I GHE
Sbjct: 5 VLHGPYDLRLEEVDDPIPKNDWVRIRVKRIGICGTDKAFY-KGT--YKLMKKPLIPGHEI 61
Query: 246 SGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRY 425
+G++ +G + +G +V E V C C +C+ G Y CP G + Y
Sbjct: 62 AGIIDMVGENAPDSLIGHKVTTEINVYCGKCWYCRHGMYTHCPYRETIGITR-DGGMAEY 120
Query: 426 YKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLLTM 596
D + D + + A +EPLA + + V + VLG GPIGLL++
Sbjct: 121 VLTRKDL-IHVVDDLDFDIIAFIEPLAAVVEMIEMQRVEPLSNIAVLGIGPIGLLSI 176
>UniRef50_Q48FD6 Cluster: Oxidoreductase, zinc-binding; n=2;
Pseudomonas syringae group|Rep: Oxidoreductase,
zinc-binding - Pseudomonas syringae pv. phaseolicola
(strain 1448A / Race 6)
Length = 340
Score = 86.6 bits (205), Expect = 4e-16
Identities = 54/176 (30%), Positives = 87/176 (49%), Gaps = 5/176 (2%)
Frame = +3
Query: 87 LRLVQTPIPE-ISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAK 263
L LV P ++ D V + + GICG+D+ + G E +I GHEA G++
Sbjct: 12 LELVDCKDPVMLAPDGVEIDIVLSGICGTDLAVLSGREGG----EVGIIRGHEAVGIIID 67
Query: 264 IGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDM----IFCATPPVHGNLVRYYK 431
+G V +L G RV ++P C CE C+ + HLC + A HG +
Sbjct: 68 VGEGVVHLQKGMRVVVDPNEYCGVCEPCRLAKTHLCNGAGNAGLDIAGVNKHGTFAERFV 127
Query: 432 HAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLLTML 599
F ++LPD ++ G L+EP+A ++ + + AG VL+LG+GP+ L+ +
Sbjct: 128 TRERFVYQLPDDMSWAAGVLVEPVACILNNIDQAFIRAGERVLILGSGPMSLIAQI 183
>UniRef50_Q1PZD2 Cluster: Strong similarity to L-threonine
dehydrogenase; n=1; Candidatus Kuenenia
stuttgartiensis|Rep: Strong similarity to L-threonine
dehydrogenase - Candidatus Kuenenia stuttgartiensis
Length = 344
Score = 86.6 bits (205), Expect = 4e-16
Identities = 50/174 (28%), Positives = 78/174 (44%)
Frame = +3
Query: 75 KPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGV 254
+ + L LV+ P P++ +VL+++ ICG+DVH P I+GHE +G
Sbjct: 9 RASGLELVKMPEPKLGPKDVLIKVQVASICGTDVHIDDWTYWAQQRFTPPRIIGHEFAGY 68
Query: 255 VAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKH 434
V ++G +V + G+RV+ E + C YC CK G +C G Y
Sbjct: 69 VQEVGKEVTFVKAGERVSAETHISCGYCYQCKNGYREVCRKSKLLGI-DYDGTFAEYLSL 127
Query: 435 AADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLLTM 596
+K + E + EP + +S+ VL+LGAGPIGL +
Sbjct: 128 PEHVLWKDDPRIPDEWATIQEPFGNAVDTVMSEDISS-KTVLILGAGPIGLFAV 180
>UniRef50_Q2U8M8 Cluster: Threonine dehydrogenase and related
Zn-dependent dehydrogenases; n=2; Aspergillus|Rep:
Threonine dehydrogenase and related Zn-dependent
dehydrogenases - Aspergillus oryzae
Length = 365
Score = 86.6 bits (205), Expect = 4e-16
Identities = 54/190 (28%), Positives = 92/190 (48%), Gaps = 12/190 (6%)
Frame = +3
Query: 63 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKG-------QCGHFVLEE 221
A Y D+R+ + P+ S+++ L++++ GICGSD++ + +G + G L
Sbjct: 4 ARFYAAGDIRIEEVETPKGSDEKALVQVEWCGICGSDINEYVQGPMSIPHTRTGPHPLTG 63
Query: 222 ---PMIMGHEASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCA 392
P+ +GHE SG + + S +L+ G V ++P C C C + + C + F
Sbjct: 64 DILPVTLGHELSGRIIQAPS-TSSLSPGQAVIVDPRYYCSSCTACTSSVTNCCQSLGFLG 122
Query: 393 TPPVHGNLVRYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSA--GHVVLVL 566
G ++PD++ M L+EPLAV HA + GV G +LV+
Sbjct: 123 LSGGGGGFSEKVAVPPAMLHQIPDNIDMATATLIEPLAVAWHAVRCSGVKGFKGLPILVI 182
Query: 567 GAGPIGLLTM 596
G GP+G+ T+
Sbjct: 183 GGGPVGVATV 192
>UniRef50_Q6MJG4 Cluster: Putative alcohol dehydrogenase I; n=1;
Bdellovibrio bacteriovorus|Rep: Putative alcohol
dehydrogenase I - Bdellovibrio bacteriovorus
Length = 332
Score = 85.8 bits (203), Expect = 7e-16
Identities = 58/173 (33%), Positives = 83/173 (47%), Gaps = 5/173 (2%)
Frame = +3
Query: 84 DLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAK 263
+L LV+ P P +V+L++ GIC SD+H G +E MGHEA G V +
Sbjct: 12 ELSLVEVPKPTPGPLDVILKIRAAGICHSDLHVLH----GEVPYKESFTMGHEACGEVVE 67
Query: 264 IGSKV-KNLTVGDRVAIEPGVPCRYCEFCKTGRYHLC--PDMIFCATPPVHGNLVRYYKH 434
GS+V GD A+ PC +C +C+TG +LC P F G Y K
Sbjct: 68 KGSEVFGTFNPGDLYAVHGPNPCGHCNYCRTGHDNLCNDPSRTFIGLGQ-DGAYAEYLKV 126
Query: 435 AADFCFKLPDHVTMEEGAL-LEPLAVGIHACK-RGGVSAGHVVLVLGAGPIGL 587
A K+P ++ E A+ + + HA K +GGV G VL +G G +G+
Sbjct: 127 PARNIVKVPKGISPEVAAVATDAVLTPYHAIKTKGGVGLGSKVLAIGLGGLGM 179
>UniRef50_Q60AS0 Cluster: Alcohol dehydrogenase, zinc-containing;
n=5; Bacteria|Rep: Alcohol dehydrogenase,
zinc-containing - Methylococcus capsulatus
Length = 342
Score = 85.4 bits (202), Expect = 9e-16
Identities = 57/174 (32%), Positives = 88/174 (50%), Gaps = 3/174 (1%)
Frame = +3
Query: 87 LRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKI 266
LR P+PE E+LL++ G+C +++ + G+ L P++ GH+A G +A +
Sbjct: 19 LRATDLPVPEPGPGEILLQVAVCGVCHTEIDEIE-GRTAPPRL--PVVPGHQAVGRIAAL 75
Query: 267 GSKVKNLTVGDRVAIE-PGVPCRYCEFCKTGRYHLCPDMIFCAT-PPVHGNLVRYYKHAA 440
GS V +GDRV + C CEFC++GR +LC FCAT V G +Y A
Sbjct: 76 GSGVAEFALGDRVGVAWIFSACGECEFCRSGRENLC--FAFCATGRDVDGGYAQYMTVPA 133
Query: 441 DFCFKLPDHVTMEEGA-LLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLLTML 599
F F++P+ T E A LL A+G + G+ G + + G G L ++
Sbjct: 134 AFAFRIPEGFTDAEAAPLLCAGAIGYRSLNLSGLKNGQPLGLTGFGASAHLVLM 187
>UniRef50_Q9ZEX7 Cluster: Dehydrogenase; n=1; Thiobacillus sp.|Rep:
Dehydrogenase - Thiobacillus sp
Length = 422
Score = 85.4 bits (202), Expect = 9e-16
Identities = 53/169 (31%), Positives = 83/169 (49%), Gaps = 2/169 (1%)
Frame = +3
Query: 87 LRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAKI 266
+ +V+ PE V++++ GICG+D+ +++ + + GHE +G + ++
Sbjct: 92 IEVVEINRPEALPGTVVVKVGASGICGTDLRAYRQDPNS-----QDLPHGHEFAGTIVEV 146
Query: 267 GSKVKNLTVGDRVAIEP--GVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAA 440
G V +G RV + C C+FC +G + C D A P G Y +
Sbjct: 147 GEGVSRDRIGKRVTADLFLNAMCGNCQFCISGHAYHCIDK---ALPFRSGGFAEYLRVRN 203
Query: 441 DFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGL 587
F LPD + GAL+EPLAV HA + GV G + +V+GAG IGL
Sbjct: 204 AATFDLPDSIDDALGALVEPLAVSTHAIRLVGVQPGMIGVVIGAGTIGL 252
>UniRef50_Q2MFS3 Cluster: Putative
3-amino-2,3-dideoxy-scyllo-inositol 1-dehydrogenase;
n=1; Streptomyces hygroscopicus subsp.
hygroscopicus|Rep: Putative
3-amino-2,3-dideoxy-scyllo-inositol 1-dehydrogenase -
Streptomyces hygroscopicus subsp. hygroscopicus
Length = 339
Score = 85.4 bits (202), Expect = 9e-16
Identities = 58/176 (32%), Positives = 82/176 (46%), Gaps = 1/176 (0%)
Frame = +3
Query: 63 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 242
A+L P D+ + + P P + E L+R+ ICGSDV + G P + GHE
Sbjct: 4 AVLNGPRDITVTEVPGPRLPEGWALVRVAYNSICGSDVSLYNNAWHGTAF---PAVPGHE 60
Query: 243 ASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMI-FCATPPVHGNLV 419
SGVV + + + GDRV + + C C +C+ + +CP + F T P G
Sbjct: 61 WSGVVEQ--APPGQVAPGDRVVADLTLSCGQCRWCRRSQPVMCPGLREFGFTDP--GGCA 116
Query: 420 RYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGL 587
Y A +LP + EPLAV +HA R ++ G V VLG G IGL
Sbjct: 117 DYVAVPAANLVRLPPDTDLLAATQAEPLAVSLHALSRVRLAPGETVAVLGCGGIGL 172
>UniRef50_A0JVX5 Cluster: Alcohol dehydrogenase, zinc-binding domain
protein; n=1; Arthrobacter sp. FB24|Rep: Alcohol
dehydrogenase, zinc-binding domain protein -
Arthrobacter sp. (strain FB24)
Length = 355
Score = 85.4 bits (202), Expect = 9e-16
Identities = 54/177 (30%), Positives = 88/177 (49%), Gaps = 1/177 (0%)
Frame = +3
Query: 63 ALLYKPNDLRLVQTPIPE-ISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGH 239
A+L NDL P P+ + E+ VL+R+ VG+CGSDV + G+ H+ P+++GH
Sbjct: 4 AILNGLNDLEYADIPEPQPVGENPVLVRVGAVGVCGSDVLRYGHGKAYHY----PLVLGH 59
Query: 240 EASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLV 419
E S +V + +L+ GDR A+ P + + G Y L + + HG +
Sbjct: 60 EFSAIVEEAPDS-PHLSAGDRAAVFPLLHRHGDPMSEIGEYALGTGYDYFGSRR-HGAMS 117
Query: 420 RYYKHAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGLL 590
F++P+ + + A++EP V +HA + + LV+GAGPIG L
Sbjct: 118 ERMWVPEQSIFRVPNDMPLTHAAMVEPAGVALHAMLKVQIPTHTTALVIGAGPIGAL 174
>UniRef50_A0HHZ1 Cluster: Alcohol dehydrogenase GroES-like; n=1;
Comamonas testosteroni KF-1|Rep: Alcohol dehydrogenase
GroES-like - Comamonas testosteroni KF-1
Length = 371
Score = 85.4 bits (202), Expect = 9e-16
Identities = 61/192 (31%), Positives = 91/192 (47%), Gaps = 17/192 (8%)
Frame = +3
Query: 63 ALLYKPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHE 242
A+ +P + + +PE D LLR+ G+CGSD Y+Q P+I+GHE
Sbjct: 10 AVAVEPGRTEIQELKVPEPGADSGLLRVAITGVCGSDWGYYQNLPRSR----GPLILGHE 65
Query: 243 ASGVVAKIGSKVKN---LTVGDRVAIEPGVPCRYCEFCKTGRYHLC-------PDMIFCA 392
G V +IGS + G+ VA+E +PC +CE+C++G + LC M + A
Sbjct: 66 TVGYVERIGSLAAQQWKVKEGELVALEEYLPCGHCEYCRSGEFRLCHATDWRLGGMRYGA 125
Query: 393 T-----PPVHGNLVR-YYKHAADFCFKLPDHVTMEEGALLEPLAVGIH-ACKRGGVSAGH 551
T P + G + + H ++P VT AL PL+ GI A +GG G
Sbjct: 126 TALSKEPGLWGGFAQAQHLHLNTVFHRVPTGVTPRHAALALPLSNGIEWAYLQGGAGPGQ 185
Query: 552 VVLVLGAGPIGL 587
V++ G G GL
Sbjct: 186 TVVIQGPGQQGL 197
>UniRef50_Q7UT38 Cluster: Zinc-type alcohol dehydrogenase; n=1;
Pirellula sp.|Rep: Zinc-type alcohol dehydrogenase -
Rhodopirellula baltica
Length = 342
Score = 85.0 bits (201), Expect = 1e-15
Identities = 53/154 (34%), Positives = 78/154 (50%), Gaps = 1/154 (0%)
Frame = +3
Query: 129 EVLLRMDCVGICGSDVHYWQKGQCGHF-VLEEPMIMGHEASGVVAKIGSKVKNLTVGDRV 305
E L+R+ VG+CG+D+ G G F P I GHE V +G V+N+ VGDR
Sbjct: 27 EALVRIHRVGVCGTDLG----GYLGKFPFFSYPRIPGHELGVEVVAVGEGVENVKVGDRC 82
Query: 306 AIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAADFCFKLPDHVTMEEG 485
++EP + C+ C C+ G + C G + A ++++ E+
Sbjct: 83 SVEPYINCQKCYSCERGLTNCCESHQTLGVMCDGGLTEKMILPARK--LHPANNLSYEQS 140
Query: 486 ALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGL 587
AL+E LA+G HA R V+ VLV+G+GPIGL
Sbjct: 141 ALVETLAIGCHAIDRAHVTEKDTVLVIGSGPIGL 174
>UniRef50_Q7US13 Cluster: Probable zinc-type alcohol dehydrogenase;
n=3; Bacteria|Rep: Probable zinc-type alcohol
dehydrogenase - Rhodopirellula baltica
Length = 396
Score = 84.6 bits (200), Expect = 2e-15
Identities = 52/174 (29%), Positives = 84/174 (48%), Gaps = 2/174 (1%)
Frame = +3
Query: 75 KPNDLRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGV 254
+P + + + PEI +VLL + VG+CGSD+H W + + P+++GHE G
Sbjct: 66 EPGSVEIREIDRPEIGSQDVLLEVSHVGVCGSDLHQWTAHH--SWPVNYPVVLGHEFGGH 123
Query: 255 VAKIGSKVKNLTVGDRVAIE-PGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYK 431
+ ++GS V+ GDRV E + + G Y+L P V+G + RY +
Sbjct: 124 IVQLGSDVEGWKEGDRVVSETAAIIDSNNPMSRRGLYNLDPTRKGFGY-GVNGAMTRYVR 182
Query: 432 HAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGG-VSAGHVVLVLGAGPIGLL 590
+ ++P + E L EP V +A R + G V+V+G G IG+L
Sbjct: 183 VPSRILHEVPHSLAFEHACLTEPCCVAYNAVVRNARIEPGDRVIVMGPGTIGIL 236
>UniRef50_O45687 Cluster: Alcohol dehydrogenase 2; n=3;
Caenorhabditis|Rep: Alcohol dehydrogenase 2 -
Caenorhabditis elegans
Length = 351
Score = 83.8 bits (198), Expect = 3e-15
Identities = 56/167 (33%), Positives = 80/167 (47%), Gaps = 4/167 (2%)
Frame = +3
Query: 87 LRLVQTPIPEISEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEE--PMIMGHEASGVVA 260
L + Q +P+ E+E+L++++ GIC SD+H W+ G F P+I GHE +G V
Sbjct: 22 LEVRQVSVPQPQENELLVKIEYSGICHSDLHTWE----GDFEYASICPLIGGHEGAGTVV 77
Query: 261 KIGSKVKNLTVGDRVAIE-PGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHA 437
IGSKVK +GDR I+ C CE+CKTG LC D I HG Y
Sbjct: 78 TIGSKVKGWNIGDRAGIKLINANCLNCEYCKTGHEPLC-DHIQNYGIDRHGTFQEYLTIR 136
Query: 438 ADFCFKLPDHVTMEEGA-LLEPLAVGIHACKRGGVSAGHVVLVLGAG 575
K+ + + A +L + K V G +V++ GAG
Sbjct: 137 DIDAIKVSNDTNLAAAAPVLCGGVTAYKSLKATNVKPGQIVVLTGAG 183
>UniRef50_UPI00005F10EF Cluster: COG1063: Threonine dehydrogenase
and related Zn-dependent dehydrogenases; n=1;
Escherichia coli B171|Rep: COG1063: Threonine
dehydrogenase and related Zn-dependent dehydrogenases -
Escherichia coli B171
Length = 322
Score = 83.4 bits (197), Expect = 4e-15
Identities = 50/146 (34%), Positives = 75/146 (51%), Gaps = 1/146 (0%)
Frame = +3
Query: 87 LRLVQTPIPEIS-EDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASGVVAK 263
+R+ ++ IPEI +DEV +++ G+CGSD+ K ++ P+ +GHE SG +
Sbjct: 12 VRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAHYY----PITLGHEFSGYIDA 67
Query: 264 IGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYKHAAD 443
+GS V +L GD VA P +PC C C G Y C F + G Y
Sbjct: 68 VGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGSRR-DGGFAEYIVVKRK 126
Query: 444 FCFKLPDHVTMEEGALLEPLAVGIHA 521
F LP + +E+GA +EP+ VG+ A
Sbjct: 127 NVFALPTDMPIEDGAFIEPITVGLLA 152
>UniRef50_Q2KCX6 Cluster: Probable zinc-type alcohol dehydrogenase
protein; n=2; Rhizobium|Rep: Probable zinc-type alcohol
dehydrogenase protein - Rhizobium etli (strain CFN 42 /
ATCC 51251)
Length = 339
Score = 83.4 bits (197), Expect = 4e-15
Identities = 58/172 (33%), Positives = 83/172 (48%), Gaps = 1/172 (0%)
Frame = +3
Query: 75 KPNDLRLVQTPIPEI-SEDEVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMIMGHEASG 251
+P L +V+ P P+ + V L + VGICG+D H ++ G+ H LE P +MGHE S
Sbjct: 8 EPGVLEIVERPSPDAPAPGWVRLAVSHVGICGTDYHIFE-GK--HPFLEYPRVMGHEISA 64
Query: 252 VVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLCPDMIFCATPPVHGNLVRYYK 431
V + G V L G V + P + C C C G+ + C ++ G
Sbjct: 65 TVIEAGEGV-TLAAGTSVIVNPYLSCGQCVACIKGKPNCCTNIKVLGVH-TDGAFCEEIS 122
Query: 432 HAADFCFKLPDHVTMEEGALLEPLAVGIHACKRGGVSAGHVVLVLGAGPIGL 587
A + +++E A E LA+G HA +R AG LV+GAGPIGL
Sbjct: 123 VPAGNLYPAKG-LSLEAAATTEFLAIGAHAVRRSLTGAGARALVIGAGPIGL 173
>UniRef50_Q0SAT0 Cluster: Zn-containing alcohol dehdyrogenase; n=26;
cellular organisms|Rep: Zn-containing alcohol
dehdyrogenase - Rhodococcus sp. (strain RHA1)
Length = 446
Score = 83.4 bits (197), Expect = 4e-15
Identities = 58/196 (29%), Positives = 94/196 (47%), Gaps = 18/196 (9%)
Frame = +3
Query: 57 LTALLYK-PNDLRLVQTPIPEISED-EVLLRMDCVGICGSDVHYWQKGQCGHFVLEEPMI 230
+ AL+Y P ++ + P I + +VL+++ ICGSD+H ++ G LE M+
Sbjct: 68 MKALVYDGPREVHVKDMPDARIEQPTDVLVKITSTNICGSDLHMYE----GRTDLEPGMV 123
Query: 231 MGHEASGVVAKIGSKVKNLTVGDRVAIEPGVPCRYCEFCKTGRYHLC------PDMI--- 383
+GHE G+VA++G+ V ++ GDRV + + C +C C+ G C P M
Sbjct: 124 LGHENLGIVAEVGNAVVKVSPGDRVCLPFNIGCGFCRNCEEGLTAFCLTVHPDPKMAGAA 183
Query: 384 --FCATPPVHGNLVRYYK-HAADF-CFKLPDHVTMEEG---ALLEPLAVGIHACKRGGVS 542
F P G Y + DF C +LP+ +E L + G H + +
Sbjct: 184 YGFAGMGPFWGGQAEYLRVPFGDFNCLRLPEDAQDKETDYVMLSDIFPTGWHCTRLADMQ 243
Query: 543 AGHVVLVLGAGPIGLL 590
G ++V GAGP+GL+
Sbjct: 244 PGDSMVVYGAGPVGLM 259
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 647,744,157
Number of Sequences: 1657284
Number of extensions: 13700281
Number of successful extensions: 47105
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 43666
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 46107
length of database: 575,637,011
effective HSP length: 97
effective length of database: 414,880,463
effective search space used: 42317807226
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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