Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= bmmt5e22
(546 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q16XB9 Cluster: Inwardly rectifying k+ channel, putativ... 105 5e-22
UniRef50_Q9VCL9 Cluster: CG4370-PA, isoform A; n=14; Endopterygo... 98 1e-19
UniRef50_UPI0000D56E2C Cluster: PREDICTED: similar to CG4370-PA,... 97 2e-19
UniRef50_UPI0000D56E2D Cluster: PREDICTED: similar to CG4370-PA,... 82 9e-15
UniRef50_Q21458 Cluster: Inward rectifying k (Potassium) channel... 78 2e-13
UniRef50_P48549 Cluster: G protein-activated inward rectifier po... 75 1e-12
UniRef50_P48051 Cluster: G protein-activated inward rectifier po... 75 1e-12
UniRef50_UPI0000586212 Cluster: PREDICTED: similar to BIK; Kir2.... 72 8e-12
UniRef50_Q4RG50 Cluster: Chromosome 2 SCAF15106, whole genome sh... 71 2e-11
UniRef50_P48048 Cluster: ATP-sensitive inward rectifier potassiu... 69 5e-11
UniRef50_Q16XB5 Cluster: Inwardly rectifying k+ channel, putativ... 69 7e-11
UniRef50_Q8WST7 Cluster: Inwardly rectifying potassium channel; ... 68 1e-10
UniRef50_UPI00005873FD Cluster: PREDICTED: hypothetical protein;... 65 9e-10
UniRef50_Q9NPI9 Cluster: Inward rectifier potassium channel 16 (... 65 9e-10
UniRef50_Q4SEH7 Cluster: Chromosome undetermined SCAF14620, whol... 65 1e-09
UniRef50_P78508 Cluster: ATP-sensitive inward rectifier potassiu... 65 1e-09
UniRef50_Q9W608 Cluster: EKir; n=4; Elopocephala|Rep: EKir - Ang... 64 2e-09
UniRef50_A2RVC9 Cluster: IP03029p; n=5; Sophophora|Rep: IP03029p... 64 3e-09
UniRef50_P48050 Cluster: Inward rectifier potassium channel 4 (P... 63 4e-09
UniRef50_Q15842 Cluster: ATP-sensitive inward rectifier potassiu... 63 5e-09
UniRef50_P52192 Cluster: Inward rectifier potassium channel irk-... 62 1e-08
UniRef50_Q969A5 Cluster: G-protein coupled inwardly rectifying p... 61 2e-08
UniRef50_Q17KL4 Cluster: Inward rectifier potassium channel, put... 60 4e-08
UniRef50_O60928 Cluster: Inward rectifier potassium channel 13 (... 60 4e-08
UniRef50_UPI000155C4DF Cluster: PREDICTED: similar to inwardly r... 59 8e-08
UniRef50_UPI0000E81615 Cluster: PREDICTED: similar to potassium ... 58 1e-07
UniRef50_Q4SN97 Cluster: Chromosome 8 SCAF14543, whole genome sh... 58 1e-07
UniRef50_UPI00005A5397 Cluster: PREDICTED: similar to potassium ... 58 2e-07
UniRef50_UPI0000F1ED04 Cluster: PREDICTED: similar to weakly inw... 55 9e-07
UniRef50_UPI00004A6C50 Cluster: PREDICTED: similar to ATP-sensit... 53 4e-06
UniRef50_A7BI83 Cluster: Inward rectifier potassium channel 7.1;... 53 4e-06
UniRef50_Q969A6 Cluster: G-protein coupled inwardly rectifying p... 53 4e-06
UniRef50_Q4SV22 Cluster: Chromosome undetermined SCAF13814, whol... 51 2e-05
UniRef50_UPI000058708F Cluster: PREDICTED: similar to Inward rec... 50 5e-05
UniRef50_UPI0000F1FEA6 Cluster: PREDICTED: similar to G protein-... 46 4e-04
UniRef50_A7S217 Cluster: Predicted protein; n=1; Nematostella ve... 46 8e-04
UniRef50_A7RUM3 Cluster: Predicted protein; n=2; Nematostella ve... 44 0.002
UniRef50_Q9VJ56 Cluster: CG10369-PA; n=2; Sophophora|Rep: CG1036... 43 0.005
UniRef50_UPI0000D57724 Cluster: PREDICTED: similar to CG4370-PA,... 42 0.012
UniRef50_UPI0000D57723 Cluster: PREDICTED: similar to Inward rec... 40 0.028
UniRef50_A7SE20 Cluster: Predicted protein; n=1; Nematostella ve... 40 0.050
UniRef50_A0PGH1 Cluster: Inwardly-rectifying potassium channel K... 39 0.066
UniRef50_A7SH65 Cluster: Predicted protein; n=1; Nematostella ve... 39 0.087
UniRef50_Q5LGX6 Cluster: Possible outer membrane protein; n=2; B... 38 0.20
UniRef50_Q8IK94 Cluster: Putative uncharacterized protein; n=1; ... 37 0.26
UniRef50_A0D3I0 Cluster: Chromosome undetermined scaffold_36, wh... 35 1.4
UniRef50_Q22G19 Cluster: Cyclic nucleotide-binding domain contai... 34 2.5
UniRef50_Q2U8I9 Cluster: Predicted protein; n=1; Aspergillus ory... 34 2.5
UniRef50_Q93849 Cluster: Putative uncharacterized protein irk-3;... 33 4.3
UniRef50_Q27YG9 Cluster: Replication polyprotein [Includes: Memb... 33 4.3
UniRef50_A6H129 Cluster: Inward rectifier potassium channel Irk;... 33 5.7
UniRef50_Q22EJ5 Cluster: Zinc finger protein; n=1; Tetrahymena t... 33 5.7
UniRef50_UPI000049A501 Cluster: hypothetical protein 31.t00010; ... 32 9.9
UniRef50_Q88UK4 Cluster: Prophage Lp3 protein 11; n=1; Lactobaci... 32 9.9
UniRef50_Q4A9A0 Cluster: Pullulanase; n=5; Mycoplasma hyopneumon... 32 9.9
UniRef50_Q1LEI6 Cluster: Extracellular solute-binding protein, f... 32 9.9
UniRef50_Q8MYK0 Cluster: Calcium-dependent protein kinase; n=1; ... 32 9.9
UniRef50_Q22C77 Cluster: Protein kinase domain containing protei... 32 9.9
>UniRef50_Q16XB9 Cluster: Inwardly rectifying k+ channel, putative;
n=2; Aedes aegypti|Rep: Inwardly rectifying k+ channel,
putative - Aedes aegypti (Yellowfever mosquito)
Length = 489
Score = 105 bits (253), Expect = 5e-22
Identities = 40/71 (56%), Positives = 52/71 (73%)
Frame = +1
Query: 334 FMTIVEAKWRWTLFYLFLAFCADWLFFGIIYWFIALVHGDLSEDHLPQYQNATGWVPCIK 513
F T+V+A+WR+TL L F WLFF ++YWFI +VHGDL E++LP Q ATGW PC+
Sbjct: 112 FTTLVDARWRYTLMVFALGFMGSWLFFALLYWFICMVHGDLDEENLPHNQEATGWKPCVT 171
Query: 514 NVYGFTSTFLF 546
N+Y +TS FLF
Sbjct: 172 NIYSYTSCFLF 182
>UniRef50_Q9VCL9 Cluster: CG4370-PA, isoform A; n=14;
Endopterygota|Rep: CG4370-PA, isoform A - Drosophila
melanogaster (Fruit fly)
Length = 453
Score = 98.3 bits (234), Expect = 1e-19
Identities = 45/99 (45%), Positives = 59/99 (59%), Gaps = 2/99 (2%)
Frame = +1
Query: 256 RRVLSKDGESNF-SKPLLHCRKGFSYS-FMTIVEAKWRWTLFYLFLAFCADWLFFGIIYW 429
RR + K+G+ N K L R F + T+V+ +WRWTL L+F WLFF +I+W
Sbjct: 97 RRAVFKNGDCNVVQKHLQRRRVRFLQDMYTTMVDWQWRWTLLAFALSFILSWLFFALIWW 156
Query: 430 FIALVHGDLSEDHLPQYQNATGWVPCIKNVYGFTSTFLF 546
I HGDL E HLP+ Q +GW PC+ + GFTS FLF
Sbjct: 157 LIIYTHGDLEEPHLPENQEESGWAPCVSAIDGFTSCFLF 195
>UniRef50_UPI0000D56E2C Cluster: PREDICTED: similar to CG4370-PA,
isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG4370-PA, isoform A - Tribolium castaneum
Length = 427
Score = 97.5 bits (232), Expect = 2e-19
Identities = 45/122 (36%), Positives = 64/122 (52%), Gaps = 3/122 (2%)
Frame = +1
Query: 190 LAPGTYVPRNKFYHQIPVTARNRRVLSKDGESNFSKPLLHCRKGFSYS---FMTIVEAKW 360
L PG K ++ + R + K+G+ N L R G Y F ++V+ W
Sbjct: 20 LYPGFPEIGRKIFNFVKPRKNRNRAIFKNGDCNIHHKGL-ARLGIRYLHDIFTSLVDISW 78
Query: 361 RWTLFYLFLAFCADWLFFGIIYWFIALVHGDLSEDHLPQYQNATGWVPCIKNVYGFTSTF 540
RW L LA+ WLFF +I+W I HGDL ++HLPQ Q + W PC+ N++ FTS +
Sbjct: 79 RWCLMIFALAYFVSWLFFALIWWLIMFTHGDLEDEHLPQNQAESNWTPCVLNIHNFTSCY 138
Query: 541 LF 546
LF
Sbjct: 139 LF 140
>UniRef50_UPI0000D56E2D Cluster: PREDICTED: similar to CG4370-PA,
isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG4370-PA, isoform A - Tribolium castaneum
Length = 391
Score = 81.8 bits (193), Expect = 9e-15
Identities = 33/97 (34%), Positives = 51/97 (52%)
Frame = +1
Query: 256 RRVLSKDGESNFSKPLLHCRKGFSYSFMTIVEAKWRWTLFYLFLAFCADWLFFGIIYWFI 435
RR++ K+G N +P +K F +V++ W +T+F + + WL F I+W I
Sbjct: 23 RRIILKNGNCNIHRPESKRQKYAFLQFTKLVDSSWTFTIFVFLITLLSSWLLFAAIWWLI 82
Query: 436 ALVHGDLSEDHLPQYQNATGWVPCIKNVYGFTSTFLF 546
HGD +HLPQ Q A + PC+ ++ F S LF
Sbjct: 83 CHTHGDFEPEHLPQVQKANNFTPCVYHINNFGSCLLF 119
>UniRef50_Q21458 Cluster: Inward rectifying k (Potassium) channel
family protein 2; n=2; Caenorhabditis|Rep: Inward
rectifying k (Potassium) channel family protein 2 -
Caenorhabditis elegans
Length = 514
Score = 77.8 bits (183), Expect = 2e-13
Identities = 42/98 (42%), Positives = 53/98 (54%), Gaps = 2/98 (2%)
Frame = +1
Query: 259 RVLSKDGESNFSKPLL--HCRKGFSYSFMTIVEAKWRWTLFYLFLAFCADWLFFGIIYWF 432
R++ K G N S + RK FS F T++E KWRW L Y L+F W FF +Y+
Sbjct: 82 RLVQKQGLCNISLKNVPKQRRKYFSDIFTTVIEMKWRWCLLYFSLSFMISWSFFATVYFL 141
Query: 433 IALVHGDLSEDHLPQYQNATGWVPCIKNVYGFTSTFLF 546
IA HGD+ Q NAT W PCI NV+ + FLF
Sbjct: 142 IAKQHGDIE-----QIANAT-WTPCIVNVHNELNAFLF 173
>UniRef50_P48549 Cluster: G protein-activated inward rectifier
potassium channel 1 (GIRK1) (Potassium channel, inwardly
rectifying subfamily J member 3) (Inward rectifier K(+)
channel Kir3.1); n=41; Euteleostomi|Rep: G
protein-activated inward rectifier potassium channel 1
(GIRK1) (Potassium channel, inwardly rectifying
subfamily J member 3) (Inward rectifier K(+) channel
Kir3.1) - Homo sapiens (Human)
Length = 501
Score = 74.9 bits (176), Expect = 1e-12
Identities = 38/107 (35%), Positives = 53/107 (49%), Gaps = 2/107 (1%)
Frame = +1
Query: 232 QIPVTARNRRVLSKDGESNFSKPLL--HCRKGFSYSFMTIVEAKWRWTLFYLFLAFCADW 405
Q+ + +R + K+G N L + S F T+V+ KWRW LF L + W
Sbjct: 36 QLVPKKKRQRFVDKNGRCNVQHGNLGSETSRYLSDLFTTLVDLKWRWNLFIFILTYTVAW 95
Query: 406 LFFGIIYWFIALVHGDLSEDHLPQYQNATGWVPCIKNVYGFTSTFLF 546
LF ++W IA GDL++ H+ Y PC+ NVY F S FLF
Sbjct: 96 LFMASMWWVIAYTRGDLNKAHVGNY------TPCVANVYNFPSAFLF 136
>UniRef50_P48051 Cluster: G protein-activated inward rectifier
potassium channel 2 (GIRK2) (Potassium channel, inwardly
rectifying subfamily J member 6) (Inward rectifier K(+)
channel Kir3.2); n=98; Euteleostomi|Rep: G
protein-activated inward rectifier potassium channel 2
(GIRK2) (Potassium channel, inwardly rectifying
subfamily J member 6) (Inward rectifier K(+) channel
Kir3.2) - Homo sapiens (Human)
Length = 423
Score = 74.5 bits (175), Expect = 1e-12
Identities = 37/100 (37%), Positives = 55/100 (55%), Gaps = 3/100 (3%)
Frame = +1
Query: 256 RRVLSKDGESNFSKPLLHCRKGFSYS---FMTIVEAKWRWTLFYLFLAFCADWLFFGIIY 426
+R + KDG+ N + R+ + Y F T+V+ KWR+ L + + WLFFG+I+
Sbjct: 54 QRYVRKDGKCNVHHG--NVRETYRYLTDIFTTLVDLKWRFNLLIFVMVYTVTWLFFGMIW 111
Query: 427 WFIALVHGDLSEDHLPQYQNATGWVPCIKNVYGFTSTFLF 546
W IA + GD+ DH+ W PC+ N+ GF S FLF
Sbjct: 112 WLIAYIRGDM--DHIED----PSWTPCVTNLNGFVSAFLF 145
>UniRef50_UPI0000586212 Cluster: PREDICTED: similar to BIK; Kir2.1;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
similar to BIK; Kir2.1 - Strongylocentrotus purpuratus
Length = 532
Score = 72.1 bits (169), Expect = 8e-12
Identities = 33/97 (34%), Positives = 49/97 (50%)
Frame = +1
Query: 256 RRVLSKDGESNFSKPLLHCRKGFSYSFMTIVEAKWRWTLFYLFLAFCADWLFFGIIYWFI 435
+R++ KDG N + + F T V+ +WRW L A+ W FG++++ I
Sbjct: 76 QRLVGKDGVCNVVHTRVARLRFIEDLFTTFVDLRWRWNLMVFTFAYVVGWFLFGLVWFVI 135
Query: 436 ALVHGDLSEDHLPQYQNATGWVPCIKNVYGFTSTFLF 546
A HGDL+ +N T W PC+ N+ FT FLF
Sbjct: 136 AAAHGDLNASQ----RNLTDWEPCVYNMETFTGAFLF 168
>UniRef50_Q4RG50 Cluster: Chromosome 2 SCAF15106, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 2 SCAF15106, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 499
Score = 70.5 bits (165), Expect = 2e-11
Identities = 36/105 (34%), Positives = 51/105 (48%), Gaps = 2/105 (1%)
Frame = +1
Query: 238 PVTARNRRVLSKDGESNFSKPLL--HCRKGFSYSFMTIVEAKWRWTLFYLFLAFCADWLF 411
PV + +R + K+G N L + S F T+V+ KWRW L L + WL
Sbjct: 26 PVKRKRQRFVEKNGRCNVQHGNLGGETSRYISDLFTTLVDLKWRWNLLIFILTYTVAWLV 85
Query: 412 FGIIYWFIALVHGDLSEDHLPQYQNATGWVPCIKNVYGFTSTFLF 546
++W IA + GDLS + + + PC+ NVY F S FLF
Sbjct: 86 MASMWWVIAYIRGDLSHG-----GHDSSYTPCVANVYNFPSAFLF 125
>UniRef50_P48048 Cluster: ATP-sensitive inward rectifier potassium
channel 1; n=48; Euteleostomi|Rep: ATP-sensitive inward
rectifier potassium channel 1 - Homo sapiens (Human)
Length = 391
Score = 69.3 bits (162), Expect = 5e-11
Identities = 31/99 (31%), Positives = 54/99 (54%), Gaps = 3/99 (3%)
Frame = +1
Query: 259 RVLSKDGESNFSKPLLHCRKGFSYS---FMTIVEAKWRWTLFYLFLAFCADWLFFGIIYW 429
R++SKDG N + + F + + T+++ KWR+ + AF W FFG++++
Sbjct: 41 RLVSKDGRCNIEFGNVEAQSRFIFFVDIWTTVLDLKWRYKMTIFITAFLGSWFFFGLLWY 100
Query: 430 FIALVHGDLSEDHLPQYQNATGWVPCIKNVYGFTSTFLF 546
+A +H D LP++ + PC++N+ G TS FLF
Sbjct: 101 AVAYIHKD-----LPEFHPSANHTPCVENINGLTSAFLF 134
>UniRef50_Q16XB5 Cluster: Inwardly rectifying k+ channel, putative;
n=7; Endopterygota|Rep: Inwardly rectifying k+ channel,
putative - Aedes aegypti (Yellowfever mosquito)
Length = 449
Score = 68.9 bits (161), Expect = 7e-11
Identities = 39/111 (35%), Positives = 57/111 (51%), Gaps = 4/111 (3%)
Frame = +1
Query: 226 YHQIPVTARN--RRVLSKDGESNFSKPLL--HCRKGFSYSFMTIVEAKWRWTLFYLFLAF 393
Y Q ++R +RV+ K G+ N + + R+ F T+V+ +WRWTL L+F
Sbjct: 7 YRQTRFSSRRIRKRVIFKQGDCNVVQGNVAKRRRRYLQDIFTTLVDIQWRWTLLVFALSF 66
Query: 394 CADWLFFGIIYWFIALVHGDLSEDHLPQYQNATGWVPCIKNVYGFTSTFLF 546
WL F II++ I HGD++ T PC+ +YGFTS FLF
Sbjct: 67 ILSWLGFAIIWYLIGYSHGDMA----AHANGDTQHQPCVTFIYGFTSAFLF 113
>UniRef50_Q8WST7 Cluster: Inwardly rectifying potassium channel;
n=1; Halocynthia roretzi|Rep: Inwardly rectifying
potassium channel - Halocynthia roretzi (Sea squirt)
Length = 745
Score = 68.1 bits (159), Expect = 1e-10
Identities = 40/104 (38%), Positives = 52/104 (50%), Gaps = 5/104 (4%)
Frame = +1
Query: 250 RNRRVLSKDGESNFSKPLLHCR--KGFSYSFMTIVEAKWRWTLFYLFLAFCADWLFFGII 423
+N R + K G N ++ + + + F T V+ KWRW L AF WLFFG I
Sbjct: 144 KNCRFIKKSGHCNVGHTNVNKKPQRFLADIFTTCVDLKWRWNLLLFSAAFILSWLFFGFI 203
Query: 424 YWFIALVHGDLSEDHLPQYQNATGWVPCIKNVYG---FTSTFLF 546
YW I+ +HGD S N T + CI N+ FTSTFLF
Sbjct: 204 YWIISYIHGDFS-------TNQTD-IQCISNLESSSPFTSTFLF 239
>UniRef50_UPI00005873FD Cluster: PREDICTED: hypothetical protein;
n=2; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 496
Score = 65.3 bits (152), Expect = 9e-10
Identities = 34/104 (32%), Positives = 55/104 (52%), Gaps = 7/104 (6%)
Frame = +1
Query: 256 RRVLSKDGESNFSKPLLHCRKG--FSYSFMTIVEAKWRWTLFYLFLAFCADWLFFGIIYW 429
+R++SK+GE N + R F+ F T+++ KWRW L LA+ W+ F +++
Sbjct: 64 QRLVSKNGECNVVYTHVPSRWSDFFTDMFTTLIDLKWRWLLIIFSLAYVLGWMGFTFVWY 123
Query: 430 FIALVHGDLS-----EDHLPQYQNATGWVPCIKNVYGFTSTFLF 546
+ HGDL D++ +Y++ W PC+ NV F FLF
Sbjct: 124 ALIWYHGDLGYQDKMADNVTEYED---WEPCVYNVQNFIGAFLF 164
>UniRef50_Q9NPI9 Cluster: Inward rectifier potassium channel 16
(Potassium channel, inwardly rectifying subfamily J
member 16) (Inward rectifier K(+) channel Kir5.1); n=23;
Tetrapoda|Rep: Inward rectifier potassium channel 16
(Potassium channel, inwardly rectifying subfamily J
member 16) (Inward rectifier K(+) channel Kir5.1) - Homo
sapiens (Human)
Length = 418
Score = 65.3 bits (152), Expect = 9e-10
Identities = 39/100 (39%), Positives = 49/100 (49%), Gaps = 3/100 (3%)
Frame = +1
Query: 256 RRVLSKDGESNFSKPLLHCRKGFSYS---FMTIVEAKWRWTLFYLFLAFCADWLFFGIIY 426
RR+L KDG N + G SY F T+V+ KWR L++ WL FG ++
Sbjct: 34 RRLLHKDGSCNVYFKHIFGEWG-SYVVDIFTTLVDTKWRHMFVIFSLSYILSWLIFGSVF 92
Query: 427 WFIALVHGDLSEDHLPQYQNATGWVPCIKNVYGFTSTFLF 546
W IA HGDL D P PC+ NV+ FT FLF
Sbjct: 93 WLIAFHHGDLLND--PDI------TPCVDNVHSFTGAFLF 124
>UniRef50_Q4SEH7 Cluster: Chromosome undetermined SCAF14620, whole
genome shotgun sequence; n=2; Tetraodontidae|Rep:
Chromosome undetermined SCAF14620, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 312
Score = 64.9 bits (151), Expect = 1e-09
Identities = 35/102 (34%), Positives = 54/102 (52%), Gaps = 3/102 (2%)
Frame = +1
Query: 250 RNRRVLSKDGESNFSKPLLHCRKGFSYS---FMTIVEAKWRWTLFYLFLAFCADWLFFGI 420
R R+++KDG N + F+ + T VE +WR+ LF AF W FG+
Sbjct: 1 RRTRLVTKDGRCNIEYGNIKYSNHFALLADFWTTFVEIRWRFVLFLFIAAFTLSWFLFGL 60
Query: 421 IYWFIALVHGDLSEDHLPQYQNATGWVPCIKNVYGFTSTFLF 546
++++IA +GDL+ + P N T PC+ NV G T+ FL+
Sbjct: 61 LWYWIARTNGDLAWQNPP--SNHT---PCVDNVVGLTTAFLY 97
>UniRef50_P78508 Cluster: ATP-sensitive inward rectifier potassium
channel 10 (Potassium channel, inwardly rectifying
subfamily J member 10) (Inward rectifier K(+) channel
Kir1.2); n=60; Euteleostomi|Rep: ATP-sensitive inward
rectifier potassium channel 10 (Potassium channel,
inwardly rectifying subfamily J member 10) (Inward
rectifier K(+) channel Kir1.2) - Homo sapiens (Human)
Length = 379
Score = 64.9 bits (151), Expect = 1e-09
Identities = 37/102 (36%), Positives = 52/102 (50%), Gaps = 3/102 (2%)
Frame = +1
Query: 250 RNRRVLSKDGESNFSKPLLHCRKGFSYS---FMTIVEAKWRWTLFYLFLAFCADWLFFGI 420
R RRVL+KDG SN + K F Y + T ++ +WR+ L F W FG+
Sbjct: 26 RRRRVLTKDGRSNVRMEHI-ADKRFLYLKDLWTTFIDMQWRYKLLLFSATFAGTWFLFGV 84
Query: 421 IYWFIALVHGDLSEDHLPQYQNATGWVPCIKNVYGFTSTFLF 546
+++ +A+ HGDL E L N T PC+ V+ T FLF
Sbjct: 85 VWYLVAVAHGDLLE--LDPPANHT---PCVVQVHTLTGAFLF 121
>UniRef50_Q9W608 Cluster: EKir; n=4; Elopocephala|Rep: EKir -
Anguilla japonica (Japanese eel)
Length = 372
Score = 64.1 bits (149), Expect = 2e-09
Identities = 39/104 (37%), Positives = 55/104 (52%), Gaps = 3/104 (2%)
Frame = +1
Query: 244 TARNRRVLSKDGESNFSKPLLHCRKGFSYS--FMTIVEAKWRWTLFYLF-LAFCADWLFF 414
T R R + +DG + + G + F T+VE +WR +F LF L++ WLFF
Sbjct: 29 TDRKPRYIQRDGSCRLALEHVPGHLGLYVTDIFTTLVEIRWR-VMFLLFSLSYILSWLFF 87
Query: 415 GIIYWFIALVHGDLSEDHLPQYQNATGWVPCIKNVYGFTSTFLF 546
G+++W IAL HGDL + G PC+ NV FT+ FLF
Sbjct: 88 GLLFWIIALAHGDL-------VGLSDG--PCVDNVRSFTAAFLF 122
>UniRef50_A2RVC9 Cluster: IP03029p; n=5; Sophophora|Rep: IP03029p -
Drosophila melanogaster (Fruit fly)
Length = 535
Score = 63.7 bits (148), Expect = 3e-09
Identities = 40/117 (34%), Positives = 56/117 (47%), Gaps = 9/117 (7%)
Frame = +1
Query: 223 FYHQIPVTARN--RRVLSKDGESNFSKPLL--HCRKGFSYSFMTIVEAKWRWTLFYLFLA 390
+Y Q ++R +RV+ K GE N + + R+ F T+V+A+WRWTL +
Sbjct: 12 WYRQTRFSSRRVRKRVVFKHGECNVVQGNVAKRRRRYLQDIFTTLVDAQWRWTLLVFAAS 71
Query: 391 FCADWLFFGIIYWFIALVHGDLSEDHLPQYQ-----NATGWVPCIKNVYGFTSTFLF 546
F W FFG I+W IA H DL +L N T V C+ V S FL+
Sbjct: 72 FVFSWAFFGFIWWIIAYAHNDLEYTNLKNQSPDLVANMTHTV-CVTQVSNMMSAFLY 127
>UniRef50_P48050 Cluster: Inward rectifier potassium channel 4
(Potassium channel, inwardly rectifying subfamily J
member 4) (Inward rectifier K(+) channel Kir2.3); n=94;
Euteleostomi|Rep: Inward rectifier potassium channel 4
(Potassium channel, inwardly rectifying subfamily J
member 4) (Inward rectifier K(+) channel Kir2.3) - Homo
sapiens (Human)
Length = 445
Score = 63.3 bits (147), Expect = 4e-09
Identities = 42/123 (34%), Positives = 59/123 (47%), Gaps = 12/123 (9%)
Frame = +1
Query: 214 RNKFYHQIPVTARNRRVLSKDGESN--FSKPLLHCRKGFSYSFMTIVEAKWRWTLFYLFL 387
RN H +P R R + K+G+ N F+ ++ + F T V+ +WR+ L
Sbjct: 6 RNGQAH-VPRRKRRNRFVKKNGQCNVYFANLSNKSQRYMADIFTTCVDTRWRYMLMIFSA 64
Query: 388 AFCADWLFFGIIYWFIALVHGDL-SEDHLPQYQN-ATGW--------VPCIKNVYGFTST 537
AF WLFFG+++W IA HGDL + +P A G PCI +V GF
Sbjct: 65 AFLVSWLFFGLLFWCIAFFHGDLEASPGVPAAGGPAAGGGGAAPVAPKPCIMHVNGFLGA 124
Query: 538 FLF 546
FLF
Sbjct: 125 FLF 127
>UniRef50_Q15842 Cluster: ATP-sensitive inward rectifier potassium
channel 8 (Potassium channel, inwardly rectifying
subfamily J member 8) (Inwardly rectifier K(+) channel
Kir6.1); n=60; Bilateria|Rep: ATP-sensitive inward
rectifier potassium channel 8 (Potassium channel,
inwardly rectifying subfamily J member 8) (Inwardly
rectifier K(+) channel Kir6.1) - Homo sapiens (Human)
Length = 424
Score = 62.9 bits (146), Expect = 5e-09
Identities = 33/99 (33%), Positives = 48/99 (48%), Gaps = 3/99 (3%)
Frame = +1
Query: 259 RVLSKDGESNFSKPLLHCRKGFSYS-FMTIVEAKWRWTLFYLFLAFCADWLFFGIIYWFI 435
R ++K G N + + + F F T+V+ KWR TL ++F WL F I++W +
Sbjct: 35 RFIAKSGACNLAHKNIREQGRFLQDIFTTLVDLKWRHTLVIFTMSFLCSWLLFAIMWWLV 94
Query: 436 ALVHGDLSEDHLPQYQNATGW--VPCIKNVYGFTSTFLF 546
A HGD+ +G C+ NV FTS FLF
Sbjct: 95 AFAHGDIYAYMEKSGMEKSGLESTVCVTNVRSFTSAFLF 133
>UniRef50_P52192 Cluster: Inward rectifier potassium channel irk-1;
n=2; Caenorhabditis|Rep: Inward rectifier potassium
channel irk-1 - Caenorhabditis elegans
Length = 505
Score = 61.7 bits (143), Expect = 1e-08
Identities = 32/71 (45%), Positives = 39/71 (54%)
Frame = +1
Query: 334 FMTIVEAKWRWTLFYLFLAFCADWLFFGIIYWFIALVHGDLSEDHLPQYQNATGWVPCIK 513
F T+++ KWRW L AF W FG Y+ IALVHGDLS LP N T C+
Sbjct: 102 FTTMIDVKWRWMLMLFASAFVLSWSIFGTTYYLIALVHGDLS---LPTPVNHTA---CVM 155
Query: 514 NVYGFTSTFLF 546
N+ S+FLF
Sbjct: 156 NLDSVYSSFLF 166
>UniRef50_Q969A5 Cluster: G-protein coupled inwardly rectifying
potassium channel-B; n=1; Halocynthia roretzi|Rep:
G-protein coupled inwardly rectifying potassium
channel-B - Halocynthia roretzi (Sea squirt)
Length = 399
Score = 60.9 bits (141), Expect = 2e-08
Identities = 27/102 (26%), Positives = 48/102 (47%), Gaps = 1/102 (0%)
Frame = +1
Query: 244 TARNRRVLSKDGESNFSKPLLHCRKGFSYS-FMTIVEAKWRWTLFYLFLAFCADWLFFGI 420
T + R ++K G N + L + F T+V+ +W++ + + A W FG
Sbjct: 51 TKQPGRFMTKTGHCNIRRSALQMGTRYMTDIFTTLVDLRWKYNMIIFVFVYTAAWSMFGF 110
Query: 421 IYWFIALVHGDLSEDHLPQYQNATGWVPCIKNVYGFTSTFLF 546
++W +A V GD + + PC++NVY + + FLF
Sbjct: 111 LWWMVAFVRGDTD---INVHNGTDSRKPCVQNVYSYATAFLF 149
>UniRef50_Q17KL4 Cluster: Inward rectifier potassium channel,
putative; n=3; Culicidae|Rep: Inward rectifier potassium
channel, putative - Aedes aegypti (Yellowfever mosquito)
Length = 419
Score = 59.7 bits (138), Expect = 4e-08
Identities = 36/110 (32%), Positives = 55/110 (50%), Gaps = 4/110 (3%)
Frame = +1
Query: 229 HQIPVTARNRRVLSKDGESN---FSKPLLHCRKGFSYSFMT-IVEAKWRWTLFYLFLAFC 396
HQ R+ RV++K GE N + P R F +T +VE +WR+TL L+F
Sbjct: 14 HQGRRAIRSSRVINKAGERNVLFLNLPQKSVR--FVKDLVTTLVEEQWRYTLTAFMLSFF 71
Query: 397 ADWLFFGIIYWFIALVHGDLSEDHLPQYQNATGWVPCIKNVYGFTSTFLF 546
+ W+ F I+++ +A HGDL D + G +PC++ F LF
Sbjct: 72 SSWILFAILWYLVAYAHGDLIFDPETGERLGDGAMPCVEGATTFAGFLLF 121
>UniRef50_O60928 Cluster: Inward rectifier potassium channel 13
(Potassium channel, inwardly rectifying subfamily J
member 13) (Inward rectifier K(+) channel Kir7.1); n=22;
Euteleostomi|Rep: Inward rectifier potassium channel 13
(Potassium channel, inwardly rectifying subfamily J
member 13) (Inward rectifier K(+) channel Kir7.1) - Homo
sapiens (Human)
Length = 360
Score = 59.7 bits (138), Expect = 4e-08
Identities = 30/105 (28%), Positives = 57/105 (54%), Gaps = 3/105 (2%)
Frame = +1
Query: 241 VTARNRRVLSKDGESNFSKPLLHCRKGFSY---SFMTIVEAKWRWTLFYLFLAFCADWLF 411
++ R RR+++KDG S ++G +Y ++ +++ +WRW + +F WL
Sbjct: 13 LSQRYRRMVTKDGHSTLQMD--GAQRGLAYLRDAWGILMDMRWRWMMLVFSASFVVHWLV 70
Query: 412 FGIIYWFIALVHGDLSEDHLPQYQNATGWVPCIKNVYGFTSTFLF 546
F ++++ +A ++GDL DH +N T C+K + FT+ F F
Sbjct: 71 FAVLWYVLAEMNGDLELDHDAPPENHT---ICVKYITSFTAAFSF 112
>UniRef50_UPI000155C4DF Cluster: PREDICTED: similar to inwardly
rectifying potassium channel Kir4.2a; n=1;
Ornithorhynchus anatinus|Rep: PREDICTED: similar to
inwardly rectifying potassium channel Kir4.2a -
Ornithorhynchus anatinus
Length = 569
Score = 58.8 bits (136), Expect = 8e-08
Identities = 35/98 (35%), Positives = 46/98 (46%), Gaps = 2/98 (2%)
Frame = +1
Query: 259 RVLSKDGESNFSKPLLH--CRKGFSYSFMTIVEAKWRWTLFYLFLAFCADWLFFGIIYWF 432
RV+SK G SN + + T+++ KWR+ L F W FG+IY+
Sbjct: 222 RVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFGVIYYA 281
Query: 433 IALVHGDLSEDHLPQYQNATGWVPCIKNVYGFTSTFLF 546
IA +HGDL + A VPCI NV T FLF
Sbjct: 282 IAFIHGDLELSGV-----AKDHVPCIMNVDSLTGAFLF 314
>UniRef50_UPI0000E81615 Cluster: PREDICTED: similar to potassium
inwardly-rectifying channel J5; n=3; Tetrapoda|Rep:
PREDICTED: similar to potassium inwardly-rectifying
channel J5 - Gallus gallus
Length = 557
Score = 58.4 bits (135), Expect = 1e-07
Identities = 33/100 (33%), Positives = 52/100 (52%), Gaps = 1/100 (1%)
Frame = +1
Query: 250 RNRRVLSKDGESNFSKPLLHCRKGF-SYSFMTIVEAKWRWTLFYLFLAFCADWLFFGIIY 426
+ +R ++K G+ + + +K F S F TIV+ K+RW LF + + W+ FG IY
Sbjct: 212 QRQRYVTKVGKCQVNLGNIQEKKRFLSDIFTTIVDLKYRWFLFVFMMCYIVTWVVFGTIY 271
Query: 427 WFIALVHGDLSEDHLPQYQNATGWVPCIKNVYGFTSTFLF 546
+F A + D++ P+ W CI+NV F S LF
Sbjct: 272 FFDAWIRDDINHIGDPE------WKACIENVDNFISALLF 305
>UniRef50_Q4SN97 Cluster: Chromosome 8 SCAF14543, whole genome
shotgun sequence; n=6; Euteleostomi|Rep: Chromosome 8
SCAF14543, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 535
Score = 58.0 bits (134), Expect = 1e-07
Identities = 28/70 (40%), Positives = 36/70 (51%), Gaps = 2/70 (2%)
Frame = +1
Query: 256 RRVLSKDGESN--FSKPLLHCRKGFSYSFMTIVEAKWRWTLFYLFLAFCADWLFFGIIYW 429
+R + KDG N F ++ S F T V+ +WRW L L+F WL FG +W
Sbjct: 136 QRFVGKDGRCNVTFVNMSERGQRYLSDLFTTCVDIRWRWMLIIFTLSFLLSWLLFGFAFW 195
Query: 430 FIALVHGDLS 459
IA HGDLS
Sbjct: 196 LIASAHGDLS 205
>UniRef50_UPI00005A5397 Cluster: PREDICTED: similar to potassium
inwardly-rectifying channel J15 isoform 4; n=1; Canis
lupus familiaris|Rep: PREDICTED: similar to potassium
inwardly-rectifying channel J15 isoform 4 - Canis
familiaris
Length = 338
Score = 57.6 bits (133), Expect = 2e-07
Identities = 33/102 (32%), Positives = 46/102 (45%), Gaps = 2/102 (1%)
Frame = +1
Query: 247 ARNRRVLSKDGESNFSKPLLH--CRKGFSYSFMTIVEAKWRWTLFYLFLAFCADWLFFGI 420
A RV+SK G SN + + T+++ KWR+ L F W FG+
Sbjct: 24 ANRPRVMSKSGHSNVRIDKVDGIYLLYLQDLWTTVIDMKWRYKLTLFAATFVMTWFLFGV 83
Query: 421 IYWFIALVHGDLSEDHLPQYQNATGWVPCIKNVYGFTSTFLF 546
IY+ IA +HGDL ++ + PCI V T FLF
Sbjct: 84 IYYAIAFIHGDLEPS-----EDVSNHTPCIMKVDSLTGAFLF 120
>UniRef50_UPI0000F1ED04 Cluster: PREDICTED: similar to weakly inward
rectifying potassium channel, partial; n=1; Danio
rerio|Rep: PREDICTED: similar to weakly inward
rectifying potassium channel, partial - Danio rerio
Length = 165
Score = 55.2 bits (127), Expect = 9e-07
Identities = 29/75 (38%), Positives = 43/75 (57%), Gaps = 5/75 (6%)
Frame = +1
Query: 247 ARNRRVLSKDGESNFSKPLLHCRKGFSYSFM-----TIVEAKWRWTLFYLFLAFCADWLF 411
AR RR+L+KDG SN + H G S ++ T+V+ +WR+ L F W
Sbjct: 93 ARKRRILTKDGRSNVR--IEHV-SGLSALYLRDPWTTVVDMQWRYKLVLFSATFVGTWFT 149
Query: 412 FGIIYWFIALVHGDL 456
FG++++ +ALVHGDL
Sbjct: 150 FGLLWYLLALVHGDL 164
>UniRef50_UPI00004A6C50 Cluster: PREDICTED: similar to ATP-sensitive
inward rectifier potassium channel 8 (Potassium channel,
inwardly rectifying, subfamily J, member 8) (Inwardly
rectifier K(+) channel Kir6.1) (uKATP-1) isoform 2; n=1;
Canis lupus familiaris|Rep: PREDICTED: similar to
ATP-sensitive inward rectifier potassium channel 8
(Potassium channel, inwardly rectifying, subfamily J,
member 8) (Inwardly rectifier K(+) channel Kir6.1)
(uKATP-1) isoform 2 - Canis familiaris
Length = 196
Score = 53.2 bits (122), Expect = 4e-06
Identities = 23/67 (34%), Positives = 36/67 (53%), Gaps = 1/67 (1%)
Frame = +1
Query: 259 RVLSKDGESNFSKPLLHCRKGFSYS-FMTIVEAKWRWTLFYLFLAFCADWLFFGIIYWFI 435
R ++K G N + + + F F T+V+ KWR TL ++F WL F I++W +
Sbjct: 35 RFIAKSGACNLAHKNIREQGRFLQDIFTTLVDLKWRHTLVIFTMSFLCSWLLFAIMWWLV 94
Query: 436 ALVHGDL 456
A HGD+
Sbjct: 95 AFAHGDI 101
>UniRef50_A7BI83 Cluster: Inward rectifier potassium channel 7.1;
n=16; Euteleostomi|Rep: Inward rectifier potassium
channel 7.1 - Aristochromis christyi
Length = 363
Score = 53.2 bits (122), Expect = 4e-06
Identities = 25/69 (36%), Positives = 40/69 (57%), Gaps = 1/69 (1%)
Frame = +1
Query: 343 IVEAKWRWTLFYLFLAFCADWLFFGIIYWFIALVHGDLS-EDHLPQYQNATGWVPCIKNV 519
+V +WRW L +F A WL F +++ +A ++GDL+ +DH Q G V C+K++
Sbjct: 66 LVSLRWRWVLLAFCTSFLAHWLLFACLWYLLAHLNGDLAVQDHDAPPQ---GHVLCVKHI 122
Query: 520 YGFTSTFLF 546
FT+ F F
Sbjct: 123 TSFTAAFSF 131
>UniRef50_Q969A6 Cluster: G-protein coupled inwardly rectifying
potassium channel-A; n=1; Halocynthia roretzi|Rep:
G-protein coupled inwardly rectifying potassium
channel-A - Halocynthia roretzi (Sea squirt)
Length = 612
Score = 53.2 bits (122), Expect = 4e-06
Identities = 30/100 (30%), Positives = 48/100 (48%), Gaps = 1/100 (1%)
Frame = +1
Query: 250 RNRRVLSKDGESNFSKPLLHCRKGF-SYSFMTIVEAKWRWTLFYLFLAFCADWLFFGIIY 426
R R ++K+G N + R + S F T+V+ +WR+ + + WL F ++
Sbjct: 69 RQTRFVTKNGHCNVRHGNVEDRSRYLSDLFTTLVDLEWRYNVMIFISTYTITWLVFAFVW 128
Query: 427 WFIALVHGDLSEDHLPQYQNATGWVPCIKNVYGFTSTFLF 546
WFI+ DL+ D +N T C+ + FTS FLF
Sbjct: 129 WFISFCRNDLNLD----VKNQT---VCVIGIKSFTSAFLF 161
>UniRef50_Q4SV22 Cluster: Chromosome undetermined SCAF13814, whole
genome shotgun sequence; n=1; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF13814,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 276
Score = 51.2 bits (117), Expect = 2e-05
Identities = 23/65 (35%), Positives = 39/65 (60%), Gaps = 1/65 (1%)
Frame = +1
Query: 355 KWRWTLFYLFLAFCADWLFFGIIYWFIALVHGDLS-EDHLPQYQNATGWVPCIKNVYGFT 531
+WRW L ++F + WL F +++ +A ++GDL+ +DH Q G V C+K++ FT
Sbjct: 54 RWRWVLLAFCISFLSHWLLFACLWYLLAHLNGDLAVKDHDAPPQ---GHVVCVKHINSFT 110
Query: 532 STFLF 546
+ F F
Sbjct: 111 AAFSF 115
>UniRef50_UPI000058708F Cluster: PREDICTED: similar to Inward
rectifying k (potassium) channel family protein 2; n=1;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
Inward rectifying k (potassium) channel family protein 2
- Strongylocentrotus purpuratus
Length = 444
Score = 49.6 bits (113), Expect = 5e-05
Identities = 34/109 (31%), Positives = 49/109 (44%), Gaps = 3/109 (2%)
Frame = +1
Query: 229 HQIPVTARNRRVLSKDGESN--FSKPLLHCR-KGFSYSFMTIVEAKWRWTLFYLFLAFCA 399
H +P + RR++ K+G N F H + F F T V+ WR+ + + L F
Sbjct: 68 HTVP---KRRRLVEKNGRCNVEFESKAKHWWFQFFRDIFTTSVDMPWRYNILMVCLGFII 124
Query: 400 DWLFFGIIYWFIALVHGDLSEDHLPQYQNATGWVPCIKNVYGFTSTFLF 546
WL F IY+ IA GD Q N+ W PC +N + S L+
Sbjct: 125 TWLAFAGIYYAIAWGRGDFE-----QLDNSE-WSPCFRNFLNWNSALLY 167
>UniRef50_UPI0000F1FEA6 Cluster: PREDICTED: similar to G
protein-coupled inwardly rectifying potassium channel
Kir3.4; n=2; Danio rerio|Rep: PREDICTED: similar to G
protein-coupled inwardly rectifying potassium channel
Kir3.4 - Danio rerio
Length = 535
Score = 46.4 bits (105), Expect = 4e-04
Identities = 30/104 (28%), Positives = 48/104 (46%), Gaps = 1/104 (0%)
Frame = +1
Query: 238 PVTARNRRVLSKDGESNFSKPLLHCRKGFSYS-FMTIVEAKWRWTLFYLFLAFCADWLFF 414
P + RR +SKDG+ + ++ F F + V+ ++RW LF + + W F
Sbjct: 161 PEIRQQRRYVSKDGKCRVDLAHMAEKERFLADIFTSFVDLQYRWFLFVFMMCYTVTWFIF 220
Query: 415 GIIYWFIALVHGDLSEDHLPQYQNATGWVPCIKNVYGFTSTFLF 546
+Y A + GDL +H P + C +N+ GF S LF
Sbjct: 221 AGLYSLNAFLRGDL--EH-PADTDV-----CFQNIDGFVSALLF 256
>UniRef50_A7S217 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 317
Score = 45.6 bits (103), Expect = 8e-04
Identities = 27/98 (27%), Positives = 46/98 (46%), Gaps = 2/98 (2%)
Frame = +1
Query: 259 RVLSKDGESNFSKPLLHCRKGFSYS--FMTIVEAKWRWTLFYLFLAFCADWLFFGIIYWF 432
R++S+ G+ N + + +K + F T+++AKW W F WLFFG ++W
Sbjct: 1 RLVSRRGKVNVTAANVENKKALYLADPFTTLLDAKWGWIFLAFASGFVTSWLFFGTLWWM 60
Query: 433 IALVHGDLSEDHLPQYQNATGWVPCIKNVYGFTSTFLF 546
I + ++ A+ C+ NV + S FLF
Sbjct: 61 IVKLR--------TRFDTAS----CVDNVDSWISAFLF 86
>UniRef50_A7RUM3 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 320
Score = 44.4 bits (100), Expect = 0.002
Identities = 27/98 (27%), Positives = 48/98 (48%), Gaps = 1/98 (1%)
Frame = +1
Query: 256 RRVLSKDGESNFSKPLLHCRKGF-SYSFMTIVEAKWRWTLFYLFLAFCADWLFFGIIYWF 432
RR++ K G N + + + + F T+++A+WR+ ++F WL FG ++W
Sbjct: 2 RRLIGKKGTVNIVSDVPRRPQLYLADHFTTLIDARWRYVFLIFTVSFLVSWLIFGSLWWG 61
Query: 433 IALVHGDLSEDHLPQYQNATGWVPCIKNVYGFTSTFLF 546
+ L + +Y N + CI+ V +TS FLF
Sbjct: 62 VYL--------YRQKYFN----IECIEKVDSWTSAFLF 87
>UniRef50_Q9VJ56 Cluster: CG10369-PA; n=2; Sophophora|Rep:
CG10369-PA - Drosophila melanogaster (Fruit fly)
Length = 442
Score = 42.7 bits (96), Expect = 0.005
Identities = 24/99 (24%), Positives = 46/99 (46%), Gaps = 3/99 (3%)
Frame = +1
Query: 259 RVLSKDGESNFSKPLLHCRKGFSYS---FMTIVEAKWRWTLFYLFLAFCADWLFFGIIYW 429
RV+ K+G+ N + K + Y T++E +W++ L ++ WL F + +
Sbjct: 113 RVMEKNGKENVVFRRIP-EKSWRYMRDLVTTLMELEWKYMLTLFLGSYFLSWLLFAALCY 171
Query: 430 FIALVHGDLSEDHLPQYQNATGWVPCIKNVYGFTSTFLF 546
+A HGD D + + G PCI V+ + + ++
Sbjct: 172 VVAYSHGDFIFDPVSGKRMGEGVDPCIYGVHSWVAMIIY 210
>UniRef50_UPI0000D57724 Cluster: PREDICTED: similar to CG4370-PA,
isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG4370-PA, isoform A - Tribolium castaneum
Length = 395
Score = 41.5 bits (93), Expect = 0.012
Identities = 20/69 (28%), Positives = 33/69 (47%)
Frame = +1
Query: 340 TIVEAKWRWTLFYLFLAFCADWLFFGIIYWFIALVHGDLSEDHLPQYQNATGWVPCIKNV 519
T++ + W+WTL L + + W F ++ ++L +GDL NAT PC+ +
Sbjct: 79 TLIVSDWKWTLIALSITYLVLWFVFAYVWMMVSLNNGDLDAG------NAT--KPCLNGI 130
Query: 520 YGFTSTFLF 546
F LF
Sbjct: 131 QSFAGYLLF 139
>UniRef50_UPI0000D57723 Cluster: PREDICTED: similar to Inward
rectifier potassium channel 2 (Potassium channel,
inwardly rectifying subfamily J member 2) (Inward
rectifier K(+) channel Kir2.1) (RBL-IRK1); n=1;
Tribolium castaneum|Rep: PREDICTED: similar to Inward
rectifier potassium channel 2 (Potassium channel,
inwardly rectifying subfamily J member 2) (Inward
rectifier K(+) channel Kir2.1) (RBL-IRK1) - Tribolium
castaneum
Length = 329
Score = 40.3 bits (90), Expect = 0.028
Identities = 26/91 (28%), Positives = 45/91 (49%), Gaps = 5/91 (5%)
Frame = +1
Query: 244 TARNRRVLSKDGESNFSKPLLHCRKGFSYSFM--TIVEAKWRWTLFYLFLAFCADWLFFG 417
T+ RV+SK G N + + + + + T++ +WRW + L L A + FG
Sbjct: 36 TSHFSRVISKSGRLNTFQVKIPRKYANYFKDLGNTLLNIRWRWIMTALCLVNFASFFLFG 95
Query: 418 IIYWFIALVHGDL-SEDH--LPQYQNATGWV 501
++Y +IA GD S D + +N TG++
Sbjct: 96 LLYMWIAYASGDFDSTDDFCIVNTKNLTGYI 126
>UniRef50_A7SE20 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 317
Score = 39.5 bits (88), Expect = 0.050
Identities = 12/39 (30%), Positives = 22/39 (56%)
Frame = +1
Query: 334 FMTIVEAKWRWTLFYLFLAFCADWLFFGIIYWFIALVHG 450
F T++++KWRW A+ W+ FG +++ I + G
Sbjct: 32 FTTMIDSKWRWISLLFITAYTGSWMGFGCVWYLITYLRG 70
>UniRef50_A0PGH1 Cluster: Inwardly-rectifying potassium channel
Kir7.1S; n=1; Homo sapiens|Rep: Inwardly-rectifying
potassium channel Kir7.1S - Homo sapiens (Human)
Length = 94
Score = 39.1 bits (87), Expect = 0.066
Identities = 17/67 (25%), Positives = 36/67 (53%), Gaps = 3/67 (4%)
Frame = +1
Query: 241 VTARNRRVLSKDGESNFSKPLLHCRKGFSY---SFMTIVEAKWRWTLFYLFLAFCADWLF 411
++ R RR+++KDG S ++G +Y ++ +++ +WRW + +F WL
Sbjct: 13 LSQRYRRMVTKDGHSTLQMD--GAQRGLAYLRDAWGILMDMRWRWMMLVFSASFVVHWLV 70
Query: 412 FGIIYWF 432
F +++ F
Sbjct: 71 FAVLWCF 77
>UniRef50_A7SH65 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 307
Score = 38.7 bits (86), Expect = 0.087
Identities = 11/36 (30%), Positives = 20/36 (55%)
Frame = +1
Query: 343 IVEAKWRWTLFYLFLAFCADWLFFGIIYWFIALVHG 450
+++ KW W + +++ W+ FG I+W I L G
Sbjct: 1 MIDMKWHWVILLFCVSYILSWVLFGTIWWLIVLSRG 36
>UniRef50_Q5LGX6 Cluster: Possible outer membrane protein; n=2;
Bacteroides fragilis|Rep: Possible outer membrane
protein - Bacteroides fragilis (strain ATCC 25285 / NCTC
9343)
Length = 588
Score = 37.5 bits (83), Expect = 0.20
Identities = 17/53 (32%), Positives = 32/53 (60%), Gaps = 2/53 (3%)
Frame = +1
Query: 157 DGKFV--FQFVQNLAPGTYVPRNKFYHQIPVTARNRRVLSKDGESNFSKPLLH 309
DGK+V F+F++N+ + Y Q+P++ R V K+GE+N++ L++
Sbjct: 358 DGKYVEVFRFIKNVYNKNNIHTGYTYVQLPISKRGNTVTCKEGETNYTLSLIN 410
>UniRef50_Q8IK94 Cluster: Putative uncharacterized protein; n=1;
Plasmodium falciparum 3D7|Rep: Putative uncharacterized
protein - Plasmodium falciparum (isolate 3D7)
Length = 2943
Score = 37.1 bits (82), Expect = 0.26
Identities = 22/58 (37%), Positives = 29/58 (50%), Gaps = 4/58 (6%)
Frame = -3
Query: 196 VPNFERIGK-QIFRLPIHQIFR---CNLTLYSNFQHRKLYSKSISHYLTNNKSDNLKY 35
VP+ + K IF I+ I NL +N ++YS IS YL NN+ DNL Y
Sbjct: 576 VPDLINLNKLNIFEFSINVIVEPVLLNLLFLNNRMTHEIYSNKISEYLENNEKDNLNY 633
>UniRef50_A0D3I0 Cluster: Chromosome undetermined scaffold_36, whole
genome shotgun sequence; n=4; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_36,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 544
Score = 34.7 bits (76), Expect = 1.4
Identities = 24/96 (25%), Positives = 45/96 (46%), Gaps = 1/96 (1%)
Frame = +1
Query: 22 LRLIDILNYQIYYSLNSEILILNTIFYVGS*SIMSDYNEKSDEWEDGKFVFQFVQNLAPG 201
+++ID + + S N+ L T +Y+ + YNEK D W G ++ F+ P
Sbjct: 247 IKVIDFGTSRYFSSNNNMQKKLGTPYYIAPEVLNGQYNEKVDIWSCGVILYIFLCGYPPF 306
Query: 202 TYVPRNKFYHQIPVTARNRRVLSKDGE-SNFSKPLL 306
T N+ + ++ +N +++ D + S SK L
Sbjct: 307 TGKNENEIFEKV----KNAKLIFDDEDWSTVSKDAL 338
>UniRef50_Q22G19 Cluster: Cyclic nucleotide-binding domain containing
protein; n=3; Eukaryota|Rep: Cyclic nucleotide-binding
domain containing protein - Tetrahymena thermophila SB210
Length = 1227
Score = 33.9 bits (74), Expect = 2.5
Identities = 18/72 (25%), Positives = 37/72 (51%)
Frame = -3
Query: 268 TKLFCFLLSLESDDRICYEVRMYPVPNFERIGKQIFRLPIHQIFRCNLTLYSNFQHRKLY 89
T + + L + D+IC+ + +P NF +I KQ+ ++ I ++ + SN+Q +K+
Sbjct: 1115 TSINNYSLIFQQFDKICHFTKFFPHNNFNQIQKQLQKIQIIKLQNIK-QINSNYQSQKIM 1173
Query: 88 SKSISHYLTNNK 53
+NN+
Sbjct: 1174 RNMNKQLPSNNQ 1185
>UniRef50_Q2U8I9 Cluster: Predicted protein; n=1; Aspergillus
oryzae|Rep: Predicted protein - Aspergillus oryzae
Length = 445
Score = 33.9 bits (74), Expect = 2.5
Identities = 13/28 (46%), Positives = 23/28 (82%)
Frame = -3
Query: 250 LLSLESDDRICYEVRMYPVPNFERIGKQ 167
++ LE+DD++ Y V+++P PNFER G++
Sbjct: 223 IVELETDDQM-YSVQLHPAPNFERRGRR 249
>UniRef50_Q93849 Cluster: Putative uncharacterized protein irk-3;
n=2; Caenorhabditis|Rep: Putative uncharacterized
protein irk-3 - Caenorhabditis elegans
Length = 374
Score = 33.1 bits (72), Expect = 4.3
Identities = 19/67 (28%), Positives = 30/67 (44%), Gaps = 7/67 (10%)
Frame = +1
Query: 259 RVLSKDGESNFSKPLLHCRKGFSYS-------FMTIVEAKWRWTLFYLFLAFCADWLFFG 417
R++SKDG++ + + R +Y F I+E WR L F W F
Sbjct: 38 RLVSKDGKTLLNNIQIPERFRQAYKWRYCRNWFHLIIECNWRTICILFLLGFIVSWTIFA 97
Query: 418 IIYWFIA 438
+IY+ I+
Sbjct: 98 VIYYVIS 104
>UniRef50_Q27YG9 Cluster: Replication polyprotein [Includes: Membrane
protein; Helicase; Protease; RNA-directed RNA polymerase
(EC 2.7.7.48)]; n=1; Nora virus|Rep: Replication
polyprotein [Includes: Membrane protein; Helicase;
Protease; RNA-directed RNA polymerase (EC 2.7.7.48)] -
Nora virus
Length = 2105
Score = 33.1 bits (72), Expect = 4.3
Identities = 18/64 (28%), Positives = 26/64 (40%), Gaps = 1/64 (1%)
Frame = +1
Query: 133 NEKSDEWEDGKFVFQFVQNLAPGTYVPRNKFYH-QIPVTARNRRVLSKDGESNFSKPLLH 309
N+ D W F QF + LAPG P + + +P R+ L S +K L
Sbjct: 1587 NDSLDHWHKSPFADQFEEQLAPGRLNPYDSYIEGDLPTNLEGRKSLILGPNSEMAKTLPE 1646
Query: 310 CRKG 321
+G
Sbjct: 1647 LDQG 1650
>UniRef50_A6H129 Cluster: Inward rectifier potassium channel Irk;
n=1; Flavobacterium psychrophilum JIP02/86|Rep: Inward
rectifier potassium channel Irk - Flavobacterium
psychrophilum (strain JIP02/86 / ATCC 49511)
Length = 318
Score = 32.7 bits (71), Expect = 5.7
Identities = 20/63 (31%), Positives = 29/63 (46%)
Frame = +1
Query: 259 RVLSKDGESNFSKPLLHCRKGFSYSFMTIVEAKWRWTLFYLFLAFCADWLFFGIIYWFIA 438
R L+KDG +N K L S+ + W++ L +FL F F IY+FI
Sbjct: 29 RFLAKDGSANIEKRGLPFFDQISWFHTLLRLPAWKFQLM-IFLVFIFVNFIFATIYYFIG 87
Query: 439 LVH 447
+ H
Sbjct: 88 IEH 90
>UniRef50_Q22EJ5 Cluster: Zinc finger protein; n=1; Tetrahymena
thermophila SB210|Rep: Zinc finger protein - Tetrahymena
thermophila SB210
Length = 561
Score = 32.7 bits (71), Expect = 5.7
Identities = 22/69 (31%), Positives = 38/69 (55%), Gaps = 1/69 (1%)
Frame = -3
Query: 247 LSLESDDRICYEVRMYPVPNFERIGKQIFRLPIHQIFRCNLTLYS-NFQHRKLYSKSISH 71
L ESDD I +M + N + + K ++P +QIF + + S NFQ++ K+I+
Sbjct: 348 LQQESDDEIKENSKMIGMENSKEMAKSDIQVPSNQIFIQSKSRGSQNFQNQVGSPKNINA 407
Query: 70 YLTNNKSDN 44
L+N++ N
Sbjct: 408 ELSNSQIQN 416
>UniRef50_UPI000049A501 Cluster: hypothetical protein 31.t00010;
n=1; Entamoeba histolytica HM-1:IMSS|Rep: hypothetical
protein 31.t00010 - Entamoeba histolytica HM-1:IMSS
Length = 544
Score = 31.9 bits (69), Expect = 9.9
Identities = 16/53 (30%), Positives = 30/53 (56%), Gaps = 1/53 (1%)
Frame = -3
Query: 247 LSLESDDRICY-EVRMYPVPNFERIGKQIFRLPIHQIFRCNLTLYSNFQHRKL 92
++L+ +CY ++ Y + + K+IF IHQ+ +CNL + S Q ++L
Sbjct: 1 MNLKQLPLLCYYKIIQYAPDSIRFVSKRIFYCFIHQLPKCNLEILSYSQQQQL 53
>UniRef50_Q88UK4 Cluster: Prophage Lp3 protein 11; n=1;
Lactobacillus plantarum|Rep: Prophage Lp3 protein 11 -
Lactobacillus plantarum
Length = 112
Score = 31.9 bits (69), Expect = 9.9
Identities = 12/33 (36%), Positives = 21/33 (63%)
Frame = +2
Query: 131 TTKNLMNGKTENLFSNSFKIWHRVHTYLVTNSI 229
T +NL+NG T+ F F +W+ +T ++N+I
Sbjct: 20 TVQNLINGTTKQQFVPLFTVWYGEYTLTISNTI 52
>UniRef50_Q4A9A0 Cluster: Pullulanase; n=5; Mycoplasma
hyopneumoniae|Rep: Pullulanase - Mycoplasma
hyopneumoniae (strain J / ATCC 25934 / NCTC 10110)
Length = 666
Score = 31.9 bits (69), Expect = 9.9
Identities = 17/39 (43%), Positives = 24/39 (61%)
Frame = +2
Query: 350 KPNGDGPYSTYFWPSAQIGYFLV*FTGSSHLSMETYLRI 466
K +G+G +STY W IGYF + + S+ M+ YLRI
Sbjct: 210 KGDGNGHFSTYNWGYDPIGYFSINSSYSTD-PMDPYLRI 247
>UniRef50_Q1LEI6 Cluster: Extracellular solute-binding protein,
family 5 precursor; n=3; Burkholderiales|Rep:
Extracellular solute-binding protein, family 5 precursor
- Ralstonia metallidurans (strain CH34 / ATCC 43123 /
DSM 2839)
Length = 575
Score = 31.9 bits (69), Expect = 9.9
Identities = 26/106 (24%), Positives = 53/106 (50%), Gaps = 4/106 (3%)
Frame = +1
Query: 238 PVTARNRRVLSKDGESNFSKPLLHCRKGFSY-SFMTIVEAKWRWTLFYLFLAFCADWLF- 411
P R + S+D ++ + +K SY ++T VEA ++T+ + F F A+W +
Sbjct: 139 PGVMEERELTSEDVLFSYGRMNASAKKIPSYYDYLTKVEAPDKYTVIFRFKEFNAEWDYR 198
Query: 412 FGIIYWFIALVHGDLSEDHLPQYQNATGWVPCIKNVY--GFTSTFL 543
FG Y + ++ +++ ++N TG P N + G ++T++
Sbjct: 199 FGWGY-YSGIMPKEVATAGAANWKNVTGTGPFTLNQFTQGNSTTYV 243
>UniRef50_Q8MYK0 Cluster: Calcium-dependent protein kinase; n=1;
Toxoplasma gondii|Rep: Calcium-dependent protein kinase
- Toxoplasma gondii
Length = 594
Score = 31.9 bits (69), Expect = 9.9
Identities = 18/61 (29%), Positives = 28/61 (45%)
Frame = +1
Query: 22 LRLIDILNYQIYYSLNSEILILNTIFYVGS*SIMSDYNEKSDEWEDGKFVFQFVQNLAPG 201
L+LID +I++ + T++YV + YNEK D W G V+ + P
Sbjct: 267 LKLIDFGFSRIFHPGVRMTAMHGTVYYVAPEVMDGKYNEKCDLWSIGVIVYMLLSGSPPF 326
Query: 202 T 204
T
Sbjct: 327 T 327
>UniRef50_Q22C77 Cluster: Protein kinase domain containing protein;
n=11; Oligohymenophorea|Rep: Protein kinase domain
containing protein - Tetrahymena thermophila SB210
Length = 521
Score = 31.9 bits (69), Expect = 9.9
Identities = 16/52 (30%), Positives = 25/52 (48%)
Frame = +1
Query: 19 TLRLIDILNYQIYYSLNSEILILNTIFYVGS*SIMSDYNEKSDEWEDGKFVF 174
TL++ID + Y N L T +Y+ + +YNEK D W G ++
Sbjct: 215 TLKVIDFGTSRYYDPENKLTQRLGTPYYIAPEVLKKEYNEKCDIWSCGVILY 266
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 525,019,442
Number of Sequences: 1657284
Number of extensions: 10638060
Number of successful extensions: 26604
Number of sequences better than 10.0: 58
Number of HSP's better than 10.0 without gapping: 25846
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 26574
length of database: 575,637,011
effective HSP length: 96
effective length of database: 416,537,747
effective search space used: 35405708495
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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