Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= bmmt5c07
(610 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q2F685 Cluster: Hydroxymethylglutaryl-CoA lyase isoform... 380 e-104
UniRef50_P35914 Cluster: Hydroxymethylglutaryl-CoA lyase, mitoch... 190 2e-47
UniRef50_Q54QI7 Cluster: Hydroxymethylglutaryl-CoA lyase; n=4; c... 183 3e-45
UniRef50_Q8TB92 Cluster: 3-hydroxymethyl-3-methylglutaryl-CoA ly... 180 2e-44
UniRef50_UPI00015B4E2A Cluster: PREDICTED: similar to hydroxymet... 175 5e-43
UniRef50_Q7NX69 Cluster: Hydroxymethylglutaryl-CoA lyase; n=3; P... 171 1e-41
UniRef50_Q1GIP4 Cluster: Hydroxymethylglutaryl-CoA lyase; n=20; ... 169 6e-41
UniRef50_Q6S014 Cluster: 3-hydroxy-3-methylglutaryl-coenzyme A l... 158 8e-38
UniRef50_Q4PD12 Cluster: Putative uncharacterized protein; n=1; ... 156 4e-37
UniRef50_Q0CWY1 Cluster: Hydroxymethylglutaryl-CoA lyase, mitoch... 153 4e-36
UniRef50_Q8D6M9 Cluster: Isopropylmalate/homocitrate/citramalate... 149 5e-35
UniRef50_A7HCC2 Cluster: Pyruvate carboxyltransferase; n=7; Bact... 144 1e-33
UniRef50_Q81Q83 Cluster: 3-hydroxy-3-methylglutarate-CoA lyase; ... 141 1e-32
UniRef50_A0KK03 Cluster: Hydroxymethylglutaryl-CoA lyase; n=3; P... 141 1e-32
UniRef50_A1SD09 Cluster: Pyruvate carboxyltransferase; n=5; Bact... 140 3e-32
UniRef50_Q9P3J2 Cluster: Related to hydroxymethylglutaryl-CoA ly... 136 5e-31
UniRef50_O34873 Cluster: YngG protein; n=2; Bacteria|Rep: YngG p... 135 9e-31
UniRef50_Q6MHG9 Cluster: Hydroxymethylglutaryl-CoA lyase; n=1; B... 128 1e-28
UniRef50_Q1YEM8 Cluster: Hydroxymethylglutaryl-CoA lyase; n=2; R... 125 7e-28
UniRef50_A6CMV0 Cluster: Hydroxymethylglutaryl-CoA lyase; n=1; B... 125 9e-28
UniRef50_Q28KR2 Cluster: Pyruvate carboxyltransferase; n=4; Prot... 122 5e-27
UniRef50_Q2B6B8 Cluster: Hydroxymethylglutaryl-CoA lyase; n=1; B... 118 1e-25
UniRef50_Q1AVC1 Cluster: Pyruvate carboxyltransferase; n=2; Acti... 118 1e-25
UniRef50_UPI00005A02C5 Cluster: PREDICTED: similar to Hydroxymet... 115 1e-24
UniRef50_Q7W6U5 Cluster: Hydroxymethylglutaryl-CoA lyase; n=3; B... 114 1e-24
UniRef50_Q0VL35 Cluster: Hydroxymethylglutaryl-CoA lyase; n=1; A... 113 2e-24
UniRef50_A3JC95 Cluster: Pyruvate carboxyltransferase; n=3; Gamm... 113 2e-24
UniRef50_Q2PQY9 Cluster: Hydroxymethylglutaryl-CoA lyase; n=1; R... 112 7e-24
UniRef50_A5UPD9 Cluster: Pyruvate carboxyltransferase; n=4; Chlo... 112 7e-24
UniRef50_A5V0V3 Cluster: Pyruvate carboxyltransferase; n=5; Chlo... 111 1e-23
UniRef50_Q2GNI7 Cluster: Putative uncharacterized protein; n=1; ... 66 3e-23
UniRef50_Q189Z3 Cluster: Putative hydroxymethylglutaryl-CoA lyas... 108 1e-22
UniRef50_Q8ELJ7 Cluster: Hydroxymethylglutaryl-CoA lyase; n=1; O... 107 3e-22
UniRef50_A1WEM7 Cluster: Pyruvate carboxyltransferase; n=2; Coma... 105 6e-22
UniRef50_A1W9T7 Cluster: Pyruvate carboxyltransferase; n=34; Pro... 101 1e-20
UniRef50_A7D6W3 Cluster: Pyruvate carboxyltransferase; n=1; Halo... 101 1e-20
UniRef50_A1HRC2 Cluster: Pyruvate carboxyltransferase; n=1; Ther... 100 2e-20
UniRef50_Q9NT06 Cluster: Putative uncharacterized protein DKFZp4... 70 2e-20
UniRef50_UPI000050F9CC Cluster: COG0119: Isopropylmalate/homocit... 99 7e-20
UniRef50_Q1YPG1 Cluster: Hydroxymethylglutaryl-CoA lyase; n=2; u... 98 2e-19
UniRef50_Q9F132 Cluster: Putative uncharacterized protein xlnI; ... 96 5e-19
UniRef50_UPI000050F830 Cluster: COG0119: Isopropylmalate/homocit... 95 2e-18
UniRef50_A3JDD8 Cluster: Hydroxymethylglutaryl-CoA lyase; n=2; P... 94 2e-18
UniRef50_A3WDQ0 Cluster: 3-hydroxy-3-methylglutarate-CoA lyase; ... 93 5e-18
UniRef50_Q9AAX5 Cluster: 3-hydroxy-3-methylglutarate-CoA lyase; ... 92 8e-18
UniRef50_Q2S361 Cluster: 3-hydroxy-3-methylglutaryl-CoA lyase; n... 92 1e-17
UniRef50_Q1EXX3 Cluster: Pyruvate carboxyltransferase; n=1; Clos... 91 1e-17
UniRef50_Q5WKL8 Cluster: Hydroxymethylglutaryl-CoA lyase; n=1; B... 91 2e-17
UniRef50_Q0S6H7 Cluster: Possible hydroxymethylglutaryl-CoA lyas... 90 4e-17
UniRef50_Q0UL76 Cluster: Putative uncharacterized protein; n=1; ... 88 1e-16
UniRef50_Q89GI1 Cluster: Bll6364 protein; n=1; Bradyrhizobium ja... 87 2e-16
UniRef50_Q120B4 Cluster: Pyruvate carboxyltransferase; n=3; Prot... 87 2e-16
UniRef50_A5P2D8 Cluster: Hydroxymethylglutaryl-CoA lyase; n=3; A... 87 2e-16
UniRef50_Q122Z2 Cluster: Pyruvate carboxyltransferase; n=64; Pro... 87 3e-16
UniRef50_A1T6B5 Cluster: Pyruvate carboxyltransferase; n=6; Myco... 87 4e-16
UniRef50_Q5SI54 Cluster: Hydroxymethylglutaryl-CoA lyase like pr... 85 1e-15
UniRef50_Q0FWC0 Cluster: Putative hydroxymethylglutaryl-CoA lyas... 82 9e-15
UniRef50_UPI0000510140 Cluster: COG0119: Isopropylmalate/homocit... 82 1e-14
UniRef50_A1UDB1 Cluster: Pyruvate carboxyltransferase; n=6; Acti... 80 4e-14
UniRef50_Q1IRS1 Cluster: Hydroxymethylglutaryl-CoA lyase; n=1; A... 78 1e-13
UniRef50_A6EGU7 Cluster: Hydroxymethylglutaryl-CoA lyase like pr... 78 1e-13
UniRef50_Q7VSS8 Cluster: Putative hydroxymethylglutaryl-CoA lyas... 76 6e-13
UniRef50_A3I2Z1 Cluster: Hydroxymethylglutaryl-CoA lyase like pr... 76 8e-13
UniRef50_Q89WI9 Cluster: Blr0698 protein; n=1; Bradyrhizobium ja... 75 1e-12
UniRef50_Q4AF29 Cluster: HMG-CoA lyase-like; n=1; Chlorobium pha... 75 1e-12
UniRef50_A6R9V0 Cluster: Putative uncharacterized protein; n=4; ... 71 3e-11
UniRef50_Q5ARE9 Cluster: Putative uncharacterized protein; n=1; ... 70 4e-11
UniRef50_Q5KLA2 Cluster: Putative uncharacterized protein; n=1; ... 69 1e-10
UniRef50_A4C110 Cluster: Hydroxymethylglutaryl-CoA lyase like pr... 65 1e-09
UniRef50_Q4AH02 Cluster: Hydroxymethylglutaryl-CoA lyase; n=1; C... 60 5e-08
UniRef50_Q583A8 Cluster: 3-hydroxy-3-methylglutaryl-CoA lyase, p... 59 7e-08
UniRef50_Q46TI7 Cluster: Pyruvate carboxyltransferase; n=2; Cupr... 57 3e-07
UniRef50_Q0S6Y1 Cluster: Hydroxymethylglutaryl-CoA lyase; n=5; A... 54 3e-06
UniRef50_Q4MV51 Cluster: YngK protein; n=15; Bacillus|Rep: YngK ... 37 0.33
UniRef50_Q6A1K1 Cluster: Putative chemosensory receptor 13; n=1;... 37 0.43
UniRef50_Q54HL4 Cluster: Putative uncharacterized protein; n=2; ... 35 1.3
UniRef50_Q8UVR7 Cluster: Enteropeptidase; n=1; Takifugu rubripes... 34 2.3
UniRef50_A5BTF3 Cluster: Putative uncharacterized protein; n=1; ... 34 3.0
UniRef50_Q2SRY1 Cluster: Peptidase C39 family protein; n=3; Myco... 33 4.0
UniRef50_A6GLW0 Cluster: Rhs family protein; n=1; Limnobacter sp... 33 4.0
UniRef50_Q86K87 Cluster: Similar to Dictyostelium discoideum (Sl... 33 4.0
UniRef50_Q22FZ2 Cluster: Hormone sensitive lipase; n=1; Tetrahym... 33 4.0
UniRef50_A1ZDW2 Cluster: Transcriptional regulator, putative; n=... 33 5.3
UniRef50_Q57926 Cluster: 2-isopropylmalate synthase 1; n=10; Eur... 33 5.3
UniRef50_A7M2Z0 Cluster: Putative uncharacterized protein; n=3; ... 33 7.0
UniRef50_A5Z9A6 Cluster: Putative uncharacterized protein; n=1; ... 33 7.0
UniRef50_A4INR3 Cluster: Na+/H+ antiporter NapA-like protein; n=... 33 7.0
UniRef50_Q8TMI0 Cluster: Transposase; n=7; Methanosarcina|Rep: T... 33 7.0
UniRef50_UPI00004986B4 Cluster: phospholipid-transporting P-type... 32 9.3
UniRef50_Q5WLW4 Cluster: Putative uncharacterized protein; n=1; ... 32 9.3
UniRef50_Q081X8 Cluster: Phosphoadenosine phosphosulfate reducta... 32 9.3
UniRef50_A2ECX7 Cluster: Major facilitator superfamily protein; ... 32 9.3
UniRef50_Q9ZRT1 Cluster: Protein gamma response 1; n=3; Arabidop... 32 9.3
>UniRef50_Q2F685 Cluster: Hydroxymethylglutaryl-CoA lyase isoform 1;
n=2; Bombyx mori|Rep: Hydroxymethylglutaryl-CoA lyase
isoform 1 - Bombyx mori (Silk moth)
Length = 338
Score = 380 bits (936), Expect = e-104
Identities = 182/184 (98%), Positives = 182/184 (98%)
Frame = +2
Query: 59 MNNVTKTCVLNILRSNNFLQRSLSTVAPEIRIYEVGPRDGLQNESKFVPTDIKVELISKI 238
MNNVT CVLNILRSNNFLQRSLSTVAPEIRIYEVGPRDGLQNESKFVPTDIKVELISKI
Sbjct: 1 MNNVTVPCVLNILRSNNFLQRSLSTVAPEIRIYEVGPRDGLQNESKFVPTDIKVELISKI 60
Query: 239 VAAGIKNVESASFVSPKWVKQMSDSVDVMKNIQRVPGVNYPVLVPNLKGYETAKQCNVEE 418
VAAGIKNVESASFVSPKWVKQMSDSVDVMKNIQRVPGVNYPVLVPNLKGYETAKQCNVEE
Sbjct: 61 VAAGIKNVESASFVSPKWVKQMSDSVDVMKNIQRVPGVNYPVLVPNLKGYETAKQCNVEE 120
Query: 419 IAIFPAGSEGFSQKNLNCSVEEGLRRFKQVADEAVRDGLRVRGYISCVVGCPYDGPIHPK 598
IAIFPAGSEGFSQKNLNCSVEEGLRRFKQVADEAVRDGLRVRGYISCVVGCPYDGPIHPK
Sbjct: 121 IAIFPAGSEGFSQKNLNCSVEEGLRRFKQVADEAVRDGLRVRGYISCVVGCPYDGPIHPK 180
Query: 599 NIAK 610
NIAK
Sbjct: 181 NIAK 184
>UniRef50_P35914 Cluster: Hydroxymethylglutaryl-CoA lyase,
mitochondrial precursor; n=227; root|Rep:
Hydroxymethylglutaryl-CoA lyase, mitochondrial precursor
- Homo sapiens (Human)
Length = 325
Score = 190 bits (464), Expect = 2e-47
Identities = 82/163 (50%), Positives = 112/163 (68%)
Frame = +2
Query: 122 SLSTVAPEIRIYEVGPRDGLQNESKFVPTDIKVELISKIVAAGIKNVESASFVSPKWVKQ 301
S+ T+ ++I EVGPRDGLQNE V T +K++LI + AG+ +E+ SFVSPKWV Q
Sbjct: 25 SMGTLPKRVKIVEVGPRDGLQNEKNIVSTPVKIKLIDMLSEAGLSVIETTSFVSPKWVPQ 84
Query: 302 MSDSVDVMKNIQRVPGVNYPVLVPNLKGYETAKQCNVEEIAIFPAGSEGFSQKNLNCSVE 481
M D +V+K IQ+ PG+NYPVL PNLKG+E A +E+ IF A SE F++KN+NCS+E
Sbjct: 85 MGDHTEVLKGIQKFPGINYPVLTPNLKGFEAAVAAGAKEVVIFGAASELFTKKNINCSIE 144
Query: 482 EGLRRFKQVADEAVRDGLRVRGYISCVVGCPYDGPIHPKNIAK 610
E +RF + A + VRGY+SC +GCPY+G I P +A+
Sbjct: 145 ESFQRFDAILKAAQSANISVRGYVSCALGCPYEGKISPAKVAE 187
>UniRef50_Q54QI7 Cluster: Hydroxymethylglutaryl-CoA lyase; n=4;
cellular organisms|Rep: Hydroxymethylglutaryl-CoA lyase
- Dictyostelium discoideum AX4
Length = 406
Score = 183 bits (446), Expect = 3e-45
Identities = 84/177 (47%), Positives = 122/177 (68%), Gaps = 4/177 (2%)
Frame = +2
Query: 62 NNVTKTCV-LNILRSNNFLQRSLSTVAP---EIRIYEVGPRDGLQNESKFVPTDIKVELI 229
NN+ +T + LN N +R + P ++I EVGPRDGLQNE VPT K++LI
Sbjct: 22 NNINRTFISLNNNNKENEFKRFQNRFGPFPEYVKIVEVGPRDGLQNEKIIVPTVDKIQLI 81
Query: 230 SKIVAAGIKNVESASFVSPKWVKQMSDSVDVMKNIQRVPGVNYPVLVPNLKGYETAKQCN 409
+++ G+ VE+ SFVSPKWV QM+D+ +V++ I++V GV+YP L PN++G+ A
Sbjct: 82 NRLAQTGLSVVEATSFVSPKWVPQMADNKEVLRGIEKVEGVSYPCLTPNIQGFRAALDAG 141
Query: 410 VEEIAIFPAGSEGFSQKNLNCSVEEGLRRFKQVADEAVRDGLRVRGYISCVVGCPYD 580
+EIA+F A SE FS+KN+N ++EE L R+K V D A +G++VRGY+SCV+GCPY+
Sbjct: 142 AKEIALFAAASESFSKKNINATIEESLARYKDVCDAARENGIKVRGYVSCVLGCPYE 198
>UniRef50_Q8TB92 Cluster: 3-hydroxymethyl-3-methylglutaryl-CoA
lyase-like protein 1; n=37; cellular organisms|Rep:
3-hydroxymethyl-3-methylglutaryl-CoA lyase-like protein
1 - Homo sapiens (Human)
Length = 340
Score = 180 bits (439), Expect = 2e-44
Identities = 79/162 (48%), Positives = 110/162 (67%)
Frame = +2
Query: 125 LSTVAPEIRIYEVGPRDGLQNESKFVPTDIKVELISKIVAAGIKNVESASFVSPKWVKQM 304
LS + ++I EVGPRDGLQNE VPTDIK+E I+++ G+ +E SFVS +WV QM
Sbjct: 41 LSGLPEFVKIVEVGPRDGLQNEKVIVPTDIKIEFINRLSQTGLSVIEVTSFVSSRWVPQM 100
Query: 305 SDSVDVMKNIQRVPGVNYPVLVPNLKGYETAKQCNVEEIAIFPAGSEGFSQKNLNCSVEE 484
+D +VMK I + PGV YPVL PNL+G+ A EI++F A SE FS+KN+NCS+EE
Sbjct: 101 ADHTEVMKGIHQYPGVRYPVLTPNLQGFHHAVAAGATEISVFGAASESFSKKNINCSIEE 160
Query: 485 GLRRFKQVADEAVRDGLRVRGYISCVVGCPYDGPIHPKNIAK 610
+ +F++V A + RGY+SC +GCPY+G I P+ + +
Sbjct: 161 SMGKFEEVVKSARHMNIPARGYVSCALGCPYEGSITPQKVTE 202
>UniRef50_UPI00015B4E2A Cluster: PREDICTED: similar to
hydroxymethylglutaryl-coa lyase; n=1; Nasonia
vitripennis|Rep: PREDICTED: similar to
hydroxymethylglutaryl-coa lyase - Nasonia vitripennis
Length = 327
Score = 175 bits (427), Expect = 5e-43
Identities = 80/171 (46%), Positives = 115/171 (67%)
Frame = +2
Query: 95 LRSNNFLQRSLSTVAPEIRIYEVGPRDGLQNESKFVPTDIKVELISKIVAAGIKNVESAS 274
LR+N + + S +RI EVGPRDGLQN K +PT+ K+ELI+++ G+++VE S
Sbjct: 12 LRNNT--RNACSFFTDIVRIVEVGPRDGLQNIRKVLPTETKIELINRLSQTGLRSVEVTS 69
Query: 275 FVSPKWVKQMSDSVDVMKNIQRVPGVNYPVLVPNLKGYETAKQCNVEEIAIFPAGSEGFS 454
FVSPKWV QM+DS +V + +++ P V Y VLVPNLKG + A + V+E+ +F A SE F+
Sbjct: 70 FVSPKWVPQMADSAEVYQGVEKNPNVEYSVLVPNLKGLDKALKLGVKEVVLFTAASETFN 129
Query: 455 QKNLNCSVEEGLRRFKQVADEAVRDGLRVRGYISCVVGCPYDGPIHPKNIA 607
QKN+NCS+ E L+ K++ ++ R ISC+ GCPY+G I P N+A
Sbjct: 130 QKNINCSIAESLKNCKEITKICKEKKIKARAVISCIAGCPYEGEIKPVNVA 180
>UniRef50_Q7NX69 Cluster: Hydroxymethylglutaryl-CoA lyase; n=3;
Proteobacteria|Rep: Hydroxymethylglutaryl-CoA lyase -
Chromobacterium violaceum
Length = 297
Score = 171 bits (415), Expect = 1e-41
Identities = 77/154 (50%), Positives = 105/154 (68%)
Frame = +2
Query: 146 IRIYEVGPRDGLQNESKFVPTDIKVELISKIVAAGIKNVESASFVSPKWVKQMSDSVDVM 325
++I EVGPRDGLQNE + + +IK+ELI ++ G+ +E+ +FVSPKWV QM+ S +V+
Sbjct: 4 VKIVEVGPRDGLQNEKRPLSAEIKLELIRRLAGTGLSAIEAGAFVSPKWVPQMAGSAEVL 63
Query: 326 KNIQRVPGVNYPVLVPNLKGYETAKQCNVEEIAIFPAGSEGFSQKNLNCSVEEGLRRFKQ 505
+ + YPVLVPN G + A EIA+F A SE FSQKN+N S+ E L+RF
Sbjct: 64 AALDTTGAIAYPVLVPNDMGLDAALAAGAREIAVFGAASESFSQKNINASIAESLQRFAS 123
Query: 506 VADEAVRDGLRVRGYISCVVGCPYDGPIHPKNIA 607
VA A+ G++VRGY+SCVVGCPY+G I P +A
Sbjct: 124 VARRALDAGVKVRGYVSCVVGCPYEGRIAPHKVA 157
>UniRef50_Q1GIP4 Cluster: Hydroxymethylglutaryl-CoA lyase; n=20;
Bacteria|Rep: Hydroxymethylglutaryl-CoA lyase -
Silicibacter sp. (strain TM1040)
Length = 288
Score = 169 bits (410), Expect = 6e-41
Identities = 76/155 (49%), Positives = 100/155 (64%)
Frame = +2
Query: 146 IRIYEVGPRDGLQNESKFVPTDIKVELISKIVAAGIKNVESASFVSPKWVKQMSDSVDVM 325
+ I+EVGPRDGLQNE + +P KV L+ + AG +E ASFVSPKWV QM+ S +V+
Sbjct: 5 VEIFEVGPRDGLQNEKRDIPVADKVALVDCLSRAGFSRIEVASFVSPKWVPQMAGSAEVL 64
Query: 326 KNIQRVPGVNYPVLVPNLKGYETAKQCNVEEIAIFPAGSEGFSQKNLNCSVEEGLRRFKQ 505
I + GV Y L PN++GYE A +EIAIF + SEGFSQ N+N S+ E + RF
Sbjct: 65 AGITKAKGVRYAALTPNMRGYEDALAARADEIAIFASASEGFSQANINASIAESIERFTP 124
Query: 506 VADEAVRDGLRVRGYISCVVGCPYDGPIHPKNIAK 610
+ + A L VRGY+SCV CPYDG + P +A+
Sbjct: 125 ILEAARHIDLPVRGYVSCVTDCPYDGAVAPDKVAE 159
>UniRef50_Q6S014 Cluster: 3-hydroxy-3-methylglutaryl-coenzyme A
lyase/3-methylglutaconyl- coenzyme A hydratase; n=3;
Trichocomaceae|Rep: 3-hydroxy-3-methylglutaryl-coenzyme
A lyase/3-methylglutaconyl- coenzyme A hydratase -
Emericella nidulans (Aspergillus nidulans)
Length = 599
Score = 158 bits (384), Expect = 8e-38
Identities = 75/160 (46%), Positives = 112/160 (70%), Gaps = 5/160 (3%)
Frame = +2
Query: 146 IRIYEVGPRDGLQNESKFVPTDIKVELISKIVAAGIKNVESASFVSPKWVKQMSDSVDVM 325
+RI EVGPRDGLQN + + + IK++LI ++ AG++ +E SFVSP+ + Q++D+ V+
Sbjct: 8 VRIVEVGPRDGLQNIPQSIDSTIKLDLIRRLRDAGLQTIELTSFVSPRAIPQLADAQVVV 67
Query: 326 KN--IQRV---PGVNYPVLVPNLKGYETAKQCNVEEIAIFPAGSEGFSQKNLNCSVEEGL 490
+N IQ++ P + PVLVPNLKG E A ++E+A+F + +EGFS+ N+NC+V+EGL
Sbjct: 68 QNADIQKLLKNPKLRLPVLVPNLKGLERALHNGIKEVAVFISATEGFSRANINCTVDEGL 127
Query: 491 RRFKQVADEAVRDGLRVRGYISCVVGCPYDGPIHPKNIAK 610
R +QVA A GL VRGY+SC+ PYDGP P ++ +
Sbjct: 128 ERARQVASRAASAGLSVRGYVSCIFADPYDGPTRPSSVLR 167
>UniRef50_Q4PD12 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 353
Score = 156 bits (378), Expect = 4e-37
Identities = 79/179 (44%), Positives = 109/179 (60%), Gaps = 14/179 (7%)
Frame = +2
Query: 116 QRSLSTVAPE--IRIYEVGPRDGLQNESKFVPTDIKVELISKIVAAGIKNVESASFVSPK 289
+R+L+T A ++I EV PRDGLQNE VPT K+ELI ++ G+ +E+ SFVSPK
Sbjct: 17 KRTLATDANRKFVKIVEVSPRDGLQNEKTIVPTATKIELIRRLAETGVPVIEAGSFVSPK 76
Query: 290 WVKQMSDSVDVMKNIQRVPGVNYPVLVPNLKGYETAKQCNVE------------EIAIFP 433
WV QM D+ V+ + P ++YPVLVPN++G E ++ E EIAIF
Sbjct: 77 WVPQMGDTPQVVAQMPVHPSISYPVLVPNMRGLEALQKLLAEYKDASKRVPPTDEIAIFT 136
Query: 434 AGSEGFSQKNLNCSVEEGLRRFKQVADEAVRDGLRVRGYISCVVGCPYDGPIHPKNIAK 610
A SE F + N NC++ E L R VA A+ GL+VRGYIS V GCPY+G + + + +
Sbjct: 137 AASESFCKANTNCTIAESLDRLSDVASRAISSGLKVRGYISVVAGCPYEGKVDAEAVGR 195
>UniRef50_Q0CWY1 Cluster: Hydroxymethylglutaryl-CoA lyase,
mitochondrial; n=5; Trichocomaceae|Rep:
Hydroxymethylglutaryl-CoA lyase, mitochondrial -
Aspergillus terreus (strain NIH 2624)
Length = 552
Score = 153 bits (370), Expect = 4e-36
Identities = 71/160 (44%), Positives = 109/160 (68%), Gaps = 5/160 (3%)
Frame = +2
Query: 146 IRIYEVGPRDGLQNESKFVPTDIKVELISKIVAAGIKNVESASFVSPKWVKQMSDSVDVM 325
+RI EVGPRDGLQN V T +K+ELI ++ +G+ +E S VSP+ V Q++D +V+
Sbjct: 8 VRIVEVGPRDGLQNIKDPVATSVKLELIRRLRESGLSTIELTSIVSPRAVPQLADCREVL 67
Query: 326 -----KNIQRVPGVNYPVLVPNLKGYETAKQCNVEEIAIFPAGSEGFSQKNLNCSVEEGL 490
K +Q+ G+ +PVLVPN KG + A + V+E+A+F + +EGFS+ N+NCSV EG+
Sbjct: 68 RDQTIKQLQQHDGLRFPVLVPNPKGLDIALEYGVKEVAVFVSATEGFSKANINCSVGEGI 127
Query: 491 RRFKQVADEAVRDGLRVRGYISCVVGCPYDGPIHPKNIAK 610
R +VA++A+R+G+ VRGY+SC+ P+ GP P + +
Sbjct: 128 ERASRVAEKAIRNGVAVRGYVSCIFEDPFSGPTKPSAVLR 167
>UniRef50_Q8D6M9 Cluster: Isopropylmalate/homocitrate/citramalate
synthase; n=4; cellular organisms|Rep:
Isopropylmalate/homocitrate/citramalate synthase -
Vibrio vulnificus
Length = 179
Score = 149 bits (361), Expect = 5e-35
Identities = 72/155 (46%), Positives = 100/155 (64%)
Frame = +2
Query: 131 TVAPEIRIYEVGPRDGLQNESKFVPTDIKVELISKIVAAGIKNVESASFVSPKWVKQMSD 310
T+ + I EVGPRDGLQNE V TD KV LI+ + G+ +E+ +FVS K V QM+D
Sbjct: 10 TLPEHVTIVEVGPRDGLQNEGA-VSTDSKVALINALSQTGLTRIEAGAFVSAKRVPQMAD 68
Query: 311 SVDVMKNIQRVPGVNYPVLVPNLKGYETAKQCNVEEIAIFPAGSEGFSQKNLNCSVEEGL 490
S+ V + I R GV Y L PN++G++ A V+ +A+F + SEGFSQ N++CS+ E L
Sbjct: 69 SLAVFEQIHRSLGVQYSALTPNMQGFQAAVSAQVDHVAVFASCSEGFSQHNIHCSIAESL 128
Query: 491 RRFKQVADEAVRDGLRVRGYISCVVGCPYDGPIHP 595
RF+ V +A + + VRGY+S V+ CPYDG P
Sbjct: 129 ERFQPVIAQAKQLNIPVRGYLSTVIDCPYDGATPP 163
>UniRef50_A7HCC2 Cluster: Pyruvate carboxyltransferase; n=7;
Bacteria|Rep: Pyruvate carboxyltransferase -
Anaeromyxobacter sp. Fw109-5
Length = 315
Score = 144 bits (350), Expect = 1e-33
Identities = 69/160 (43%), Positives = 102/160 (63%), Gaps = 8/160 (5%)
Frame = +2
Query: 134 VAPEIRIYEVGPRDGLQNESKFVPTDIKVELISKIVAAGIKNVESASFVSPKWVKQMSDS 313
+AP + +YEVGPRDGLQNE+K VP+ K+ L+ + AG++ +E+ SFVSP+W+ Q++D+
Sbjct: 1 MAPRVTVYEVGPRDGLQNEAKTVPSGDKLALVRALAGAGLRRIEATSFVSPRWIPQLADA 60
Query: 314 VDVMKNIQRVPGVNYPVLVPNLKGYETAKQC--------NVEEIAIFPAGSEGFSQKNLN 469
+V + RVPGV+Y VLVPN KG E + + A+F + SE S++N+N
Sbjct: 61 AEVTAALPRVPGVSYVVLVPNAKGLERLGEALGRAGPDHPPVDAAVFLSASETHSRRNIN 120
Query: 470 CSVEEGLRRFKQVADEAVRDGLRVRGYISCVVGCPYDGPI 589
+ E L + A+ GLRVRGY+S V GCPY+G +
Sbjct: 121 KGIAEALDEAASLVPAALGRGLRVRGYVSTVWGCPYEGRV 160
>UniRef50_Q81Q83 Cluster: 3-hydroxy-3-methylglutarate-CoA lyase;
n=27; Bacteria|Rep: 3-hydroxy-3-methylglutarate-CoA
lyase - Bacillus anthracis
Length = 303
Score = 141 bits (342), Expect = 1e-32
Identities = 68/146 (46%), Positives = 94/146 (64%)
Frame = +2
Query: 152 IYEVGPRDGLQNESKFVPTDIKVELISKIVAAGIKNVESASFVSPKWVKQMSDSVDVMKN 331
I EVGPRDGLQNE K V T KV+ I + AG+ VE +SFV PKWV ++D+ DV
Sbjct: 9 IKEVGPRDGLQNEKKIVGTKDKVKWIQLLTEAGLSYVEVSSFVHPKWVPALADANDVFSE 68
Query: 332 IQRVPGVNYPVLVPNLKGYETAKQCNVEEIAIFPAGSEGFSQKNLNCSVEEGLRRFKQVA 511
++R P V Y LVPN G E A NV+E+ +F + SE ++ N+N S++E L + +
Sbjct: 69 LKRDPNVTYAALVPNQNGLERAFLQNVDEVNVFLSASESHNKSNINKSIKEALVVIEDIT 128
Query: 512 DEAVRDGLRVRGYISCVVGCPYDGPI 589
+A+ +G +VRGY+S V GCPY+G I
Sbjct: 129 KQALFEGKKVRGYVSTVFGCPYEGDI 154
>UniRef50_A0KK03 Cluster: Hydroxymethylglutaryl-CoA lyase; n=3;
Proteobacteria|Rep: Hydroxymethylglutaryl-CoA lyase -
Aeromonas hydrophila subsp. hydrophila (strain ATCC 7966
/ NCIB 9240)
Length = 318
Score = 141 bits (342), Expect = 1e-32
Identities = 66/165 (40%), Positives = 104/165 (63%)
Frame = +2
Query: 113 LQRSLSTVAPEIRIYEVGPRDGLQNESKFVPTDIKVELISKIVAAGIKNVESASFVSPKW 292
+ R+ + ++ + E+GPRDGLQNE+ + ++ELI+++ +G++ +E +FVSP+
Sbjct: 1 MSRAQESRDDKVSLVEMGPRDGLQNEAATLSLMQRLELIARLAESGLQRIEVGAFVSPRK 60
Query: 293 VKQMSDSVDVMKNIQRVPGVNYPVLVPNLKGYETAKQCNVEEIAIFPAGSEGFSQKNLNC 472
V QM+DS + + R Y LVPNL+G + A +EI +F A S+GF++ N+
Sbjct: 61 VPQMADSAALFNALPRRGPTRYGALVPNLQGLQAAIAARADEIGLFTACSDGFTRANIGI 120
Query: 473 SVEEGLRRFKQVADEAVRDGLRVRGYISCVVGCPYDGPIHPKNIA 607
SVEE L RF + EA G++VRGY+S V+ CP+DGP PK +A
Sbjct: 121 SVEESLVRFAPLVQEARSLGIKVRGYLSTVIACPFDGPTRPKRVA 165
>UniRef50_A1SD09 Cluster: Pyruvate carboxyltransferase; n=5;
Bacteria|Rep: Pyruvate carboxyltransferase -
Nocardioides sp. (strain BAA-499 / JS614)
Length = 315
Score = 140 bits (338), Expect = 3e-32
Identities = 68/156 (43%), Positives = 99/156 (63%)
Frame = +2
Query: 122 SLSTVAPEIRIYEVGPRDGLQNESKFVPTDIKVELISKIVAAGIKNVESASFVSPKWVKQ 301
S + + + IYEVGPRDGLQNE VPTD+K E + +++AAG+ VE+ SFV PKWV Q
Sbjct: 13 SAAPMPDRVTIYEVGPRDGLQNEKSLVPTDVKAEFVRRLLAAGLPIVEATSFVHPKWVPQ 72
Query: 302 MSDSVDVMKNIQRVPGVNYPVLVPNLKGYETAKQCNVEEIAIFPAGSEGFSQKNLNCSVE 481
++D+ ++M + G + PVLVPN +G + A + V +AIF + +E F+QKNLN S++
Sbjct: 73 LADAAELMA-LLGPAGRDCPVLVPNERGLDRALELGVRHVAIFGSATETFAQKNLNRSLD 131
Query: 482 EGLRRFKQVADEAVRDGLRVRGYISCVVGCPYDGPI 589
E F+ A GL VR Y+S G P++G +
Sbjct: 132 EQFAMFEPTVRRARDAGLDVRAYVSMCFGDPWEGAV 167
>UniRef50_Q9P3J2 Cluster: Related to hydroxymethylglutaryl-CoA
lyase; n=5; Pezizomycotina|Rep: Related to
hydroxymethylglutaryl-CoA lyase - Neurospora crassa
Length = 395
Score = 136 bits (328), Expect = 5e-31
Identities = 76/194 (39%), Positives = 114/194 (58%), Gaps = 30/194 (15%)
Frame = +2
Query: 116 QRSLSTVAPEIRIYEVGPRDGLQNESKFVPTDIKVELISKIVAAGIKNVESASFVSPKWV 295
Q + T ++I EVGPRDGLQNE K +P K+ELI ++ G++ +E+ +FVSPKWV
Sbjct: 46 QPTQPTFDNRVKIVEVGPRDGLQNEKKSIPLATKIELIERLAKTGLQTIEAGAFVSPKWV 105
Query: 296 KQMSDSVDVMKNIQRVP-----GVNYPVLVPNLKGYETA-----KQCNVEE--------- 418
QM++S ++++++ + P + + L PN KG E+A K + E
Sbjct: 106 PQMANSDEILEHLLKTPPPSPVPLTFSFLAPNTKGLESALSILGKYPDAYETETTRSGKS 165
Query: 419 ----------IAIFPAGSEGFSQKNLNCSVEEGLRRFKQVADEAVRDGLRVRGYISCVVG 568
IA+F A +E FSQKNLNCS++ LR+FK+V +A + LRVR YIS V+G
Sbjct: 166 AQEGGKPALEIAVFAAATESFSQKNLNCSIDASLRQFKEVIQQAKQANLRVRAYISVVLG 225
Query: 569 CPYDG-PIHPKNIA 607
CP++G + P +A
Sbjct: 226 CPFEGYDVDPHRVA 239
>UniRef50_O34873 Cluster: YngG protein; n=2; Bacteria|Rep: YngG
protein - Bacillus subtilis
Length = 299
Score = 135 bits (326), Expect = 9e-31
Identities = 62/146 (42%), Positives = 90/146 (61%)
Frame = +2
Query: 143 EIRIYEVGPRDGLQNESKFVPTDIKVELISKIVAAGIKNVESASFVSPKWVKQMSDSVDV 322
++ I EVGPRDGLQNE ++ T+ K+ I+++ G+ +E SFV PKW+ + D++DV
Sbjct: 6 KVTIKEVGPRDGLQNEPVWIATEDKITWINQLSRTGLSYIEITSFVHPKWIPALRDAIDV 65
Query: 323 MKNIQRVPGVNYPVLVPNLKGYETAKQCNVEEIAIFPAGSEGFSQKNLNCSVEEGLRRFK 502
K I R GV Y LVPN +G E A + + E +F + SE ++KN+N S E L K
Sbjct: 66 AKGIDREKGVTYAALVPNQRGLENALEGGINEACVFMSASETHNRKNINKSTSESLHILK 125
Query: 503 QVADEAVRDGLRVRGYISCVVGCPYD 580
QV ++A + L R Y+S V GCPY+
Sbjct: 126 QVNNDAQKANLTTRAYLSTVFGCPYE 151
>UniRef50_Q6MHG9 Cluster: Hydroxymethylglutaryl-CoA lyase; n=1;
Bdellovibrio bacteriovorus|Rep:
Hydroxymethylglutaryl-CoA lyase - Bdellovibrio
bacteriovorus
Length = 311
Score = 128 bits (309), Expect = 1e-28
Identities = 67/160 (41%), Positives = 95/160 (59%), Gaps = 7/160 (4%)
Frame = +2
Query: 152 IYEVGPRDGLQNESKFVPTDIKVELISKIVAAGIKNVESASFVSPKWVKQMSDSVDVM-K 328
I E+G RDGLQNE + D +VE +++ AG K VE +FVSP WV QM+ + +V+ K
Sbjct: 7 IVEMGLRDGLQNEKTVLDADTRVEFARRLILAGTKRVEIGAFVSPTWVPQMAGTAEVVQK 66
Query: 329 NIQRVPGVNYP------VLVPNLKGYETAKQCNVEEIAIFPAGSEGFSQKNLNCSVEEGL 490
V + P VLVPN +G A V+E+AIF A SE FS KN+NCS++E
Sbjct: 67 TFALVKSGSIPKKTEFSVLVPNERGMMDAIASGVKEVAIFAACSESFSLKNINCSIDESF 126
Query: 491 RRFKQVADEAVRDGLRVRGYISCVVGCPYDGPIHPKNIAK 610
+RF+ V A + ++VRGY+S GCP++G + + K
Sbjct: 127 KRFEPVMALAKKHKIKVRGYLSTCFGCPFEGRVSEAKVVK 166
>UniRef50_Q1YEM8 Cluster: Hydroxymethylglutaryl-CoA lyase; n=2;
Rhizobiales|Rep: Hydroxymethylglutaryl-CoA lyase -
Aurantimonas sp. SI85-9A1
Length = 322
Score = 125 bits (302), Expect = 7e-28
Identities = 55/156 (35%), Positives = 97/156 (62%)
Frame = +2
Query: 143 EIRIYEVGPRDGLQNESKFVPTDIKVELISKIVAAGIKNVESASFVSPKWVKQMSDSVDV 322
++RI EVGPRDGLQNE K++PTD K+EL+ ++ AAG+ +E SF PKW+ ++D+ +V
Sbjct: 17 KVRIVEVGPRDGLQNEPKYLPTDQKIELVRRLAAAGLTEIEVTSFTHPKWIPNLADAEEV 76
Query: 323 MKNIQRVPGVNYPVLVPNLKGYETAKQCNVEEIAIFPAGSEGFSQKNLNCSVEEGLRRFK 502
+ + +P + L+PN +G + A + + + + ++ + NLN + E +
Sbjct: 77 TRAVADLPITPF-ALIPNRRGLDRAMAAGAKGVTLVVSVTDAHNTANLNRTTEASVTELL 135
Query: 503 QVADEAVRDGLRVRGYISCVVGCPYDGPIHPKNIAK 610
++ EA + GL+ R +S V GCP+DG + P+++A+
Sbjct: 136 ELEAEARQAGLKTRVSLSVVFGCPFDGAVAPEHVAQ 171
>UniRef50_A6CMV0 Cluster: Hydroxymethylglutaryl-CoA lyase; n=1;
Bacillus sp. SG-1|Rep: Hydroxymethylglutaryl-CoA lyase -
Bacillus sp. SG-1
Length = 311
Score = 125 bits (301), Expect = 9e-28
Identities = 62/152 (40%), Positives = 89/152 (58%)
Frame = +2
Query: 143 EIRIYEVGPRDGLQNESKFVPTDIKVELISKIVAAGIKNVESASFVSPKWVKQMSDSVDV 322
++ + EVGPRDGLQNE FVPTDIK++ I + AG+K +E SFVSPKWV QM D+ ++
Sbjct: 19 KVTMIEVGPRDGLQNEKNFVPTDIKIQFIRALKEAGLKEMELTSFVSPKWVPQMKDASEI 78
Query: 323 MKNIQRVPGVNYPVLVPNLKGYETAKQCNVEEIAIFPAGSEGFSQKNLNCSVEEGLRRFK 502
+++ + VL PN KG + + + +A+F S F++KN+N + E L K
Sbjct: 79 VESC--LNSERDIVLAPNRKGVDRVLETKGKAVAVFVGVSNSFNKKNINKTTAESLEELK 136
Query: 503 QVADEAVRDGLRVRGYISCVVGCPYDGPIHPK 598
+ E G VR IS CPY+G I P+
Sbjct: 137 PIVGELKEKGYFVRACISTSFYCPYEGKIPPQ 168
>UniRef50_Q28KR2 Cluster: Pyruvate carboxyltransferase; n=4;
Proteobacteria|Rep: Pyruvate carboxyltransferase -
Jannaschia sp. (strain CCS1)
Length = 319
Score = 122 bits (295), Expect = 5e-27
Identities = 55/155 (35%), Positives = 95/155 (61%)
Frame = +2
Query: 146 IRIYEVGPRDGLQNESKFVPTDIKVELISKIVAAGIKNVESASFVSPKWVKQMSDSVDVM 325
+ + EVGPRDG Q+E F+PT K+E+ + + AAG+++++ SFVSP+ V Q++D+ ++
Sbjct: 14 VTVCEVGPRDGFQSEKTFIPTARKIEIANAMFAAGLRHIQVTSFVSPRAVPQLADAAKLI 73
Query: 326 KNIQRVPGVNYPVLVPNLKGYETAKQCNVEEIAIFPAGSEGFSQKNLNCSVEEGLRRFKQ 505
+ R G L+PNLKG E A V+ + + SE + KN+N +++ L F+
Sbjct: 74 AGLDRPDGAVVSALIPNLKGAERAAAAGVDAVHTVVSASETHNLKNVNRPIDQSLADFED 133
Query: 506 VADEAVRDGLRVRGYISCVVGCPYDGPIHPKNIAK 610
VA R+G+ V G ++ GCP++G + P+ +A+
Sbjct: 134 VAKLMHREGIVVEGGMATAFGCPFEGVVPPEQVAR 168
>UniRef50_Q2B6B8 Cluster: Hydroxymethylglutaryl-CoA lyase; n=1;
Bacillus sp. NRRL B-14911|Rep: Hydroxymethylglutaryl-CoA
lyase - Bacillus sp. NRRL B-14911
Length = 308
Score = 118 bits (284), Expect = 1e-25
Identities = 63/146 (43%), Positives = 81/146 (55%)
Frame = +2
Query: 152 IYEVGPRDGLQNESKFVPTDIKVELISKIVAAGIKNVESASFVSPKWVKQMSDSVDVMKN 331
I EVGPRDGLQNE F+PT +K E IS + AG +E SFVSPKWV QM+D+ ++ +
Sbjct: 11 IIEVGPRDGLQNEKTFIPTPVKKEFISALKKAGFAEMELTSFVSPKWVPQMADAAEIAAS 70
Query: 332 IQRVPGVNYPVLVPNLKGYETAKQCNVEEIAIFPAGSEGFSQKNLNCSVEEGLRRFKQVA 511
GV VL PN KG E A IA+F S+ F++KN+N + E + +
Sbjct: 71 -SIGSGVRDFVLAPNRKGIERAYMTGCRAIAVFVGVSDSFNKKNINKTTAESMEEILPLV 129
Query: 512 DEAVRDGLRVRGYISCVVGCPYDGPI 589
E G VR IS CPY+G I
Sbjct: 130 RELKEKGYFVRACISTSFYCPYEGKI 155
>UniRef50_Q1AVC1 Cluster: Pyruvate carboxyltransferase; n=2;
Actinobacteria (class)|Rep: Pyruvate carboxyltransferase
- Rubrobacter xylanophilus (strain DSM 9941 / NBRC
16129)
Length = 297
Score = 118 bits (284), Expect = 1e-25
Identities = 55/154 (35%), Positives = 95/154 (61%), Gaps = 1/154 (0%)
Frame = +2
Query: 146 IRIYEVGPRDGLQNESKFVPTDIKVELISKIVAAGIKNVESASFVSPKWVKQMSDSVDVM 325
+ + +VGPRDGLQNE K + +++ EL ++ AG++ +E+ASFV+P+ V QM+ + +VM
Sbjct: 3 VEVVDVGPRDGLQNEEKILSPEVRAELCDRLAGAGLRRMEAASFVNPRLVPQMAGAEEVM 62
Query: 326 KNIQRVPGVNYPVLVPNLKGYETAKQCNVEEIA-IFPAGSEGFSQKNLNCSVEEGLRRFK 502
+ R P V+Y LV N +GYE A V+E+ FP ++ F+++N N + E
Sbjct: 63 AALNRRPEVSYAGLVLNERGYERAVAAGVDEVRYAFPV-TDSFARRNQNTTAGEAAGLAA 121
Query: 503 QVADEAVRDGLRVRGYISCVVGCPYDGPIHPKNI 604
++ + A DG+R+ +S GCP++G + P+ +
Sbjct: 122 RLVERARLDGVRISVTLSVAFGCPFEGRVEPERV 155
>UniRef50_UPI00005A02C5 Cluster: PREDICTED: similar to
Hydroxymethylglutaryl-CoA lyase, mitochondrial precursor
(HMG-CoA lyase) (HL) (3-hydroxy-3-methylglutarate-CoA
lyase) isoform 2; n=1; Canis lupus familiaris|Rep:
PREDICTED: similar to Hydroxymethylglutaryl-CoA lyase,
mitochondrial precursor (HMG-CoA lyase) (HL)
(3-hydroxy-3-methylglutarate-CoA lyase) isoform 2 -
Canis familiaris
Length = 191
Score = 115 bits (276), Expect = 1e-24
Identities = 51/106 (48%), Positives = 72/106 (67%)
Frame = +2
Query: 122 SLSTVAPEIRIYEVGPRDGLQNESKFVPTDIKVELISKIVAAGIKNVESASFVSPKWVKQ 301
SL T +++I EVG RDGLQNE V T K++LI + AG+ +E+ SFVSPKWV Q
Sbjct: 25 SLGTFPKQVKIVEVGARDGLQNEKNIVSTSTKIKLIDMLSEAGLPVIEATSFVSPKWVPQ 84
Query: 302 MSDSVDVMKNIQRVPGVNYPVLVPNLKGYETAKQCNVEEIAIFPAG 439
M+D +V+K IQ+ PG+NYPVL PN+KG++ A +V + ++ G
Sbjct: 85 MADCAEVLKGIQKFPGINYPVLTPNIKGFQAAMGVSVVDSSVAGLG 130
>UniRef50_Q7W6U5 Cluster: Hydroxymethylglutaryl-CoA lyase; n=3;
Burkholderiales|Rep: Hydroxymethylglutaryl-CoA lyase -
Bordetella parapertussis
Length = 308
Score = 114 bits (275), Expect = 1e-24
Identities = 57/147 (38%), Positives = 88/147 (59%), Gaps = 1/147 (0%)
Frame = +2
Query: 146 IRIYEVGPRDGLQNESKFVPTDIKVELISKIVAAGIKNVESASFVSPKWVKQMSDSVDVM 325
I I +V PRDGLQN+ VPT K+ LI + AG+++VE+ SFVSP+ V QM+D+ +++
Sbjct: 5 IHITDVSPRDGLQNQPAQVPTQEKLRLIRLLAEAGVRSVEATSFVSPRAVPQMADAAELV 64
Query: 326 KNIQ-RVPGVNYPVLVPNLKGYETAKQCNVEEIAIFPAGSEGFSQKNLNCSVEEGLRRFK 502
+ +P + VLVPNLKG E A EIA+ + +E ++KN+N + + + +
Sbjct: 65 AQVHAALPDLRTSVLVPNLKGLERALAAGAREIAVVLSATETMNRKNINMGLAQAVSVSE 124
Query: 503 QVADEAVRDGLRVRGYISCVVGCPYDG 583
Q A GLR R Y++ CP++G
Sbjct: 125 QTLAAARGAGLRTRAYVAVAFDCPFEG 151
>UniRef50_Q0VL35 Cluster: Hydroxymethylglutaryl-CoA lyase; n=1;
Alcanivorax borkumensis SK2|Rep:
Hydroxymethylglutaryl-CoA lyase - Alcanivorax
borkumensis (strain SK2 / ATCC 700651 / DSM 11573)
Length = 350
Score = 113 bits (273), Expect = 2e-24
Identities = 55/153 (35%), Positives = 89/153 (58%)
Frame = +2
Query: 131 TVAPEIRIYEVGPRDGLQNESKFVPTDIKVELISKIVAAGIKNVESASFVSPKWVKQMSD 310
T+ + I EVG RDGLQN+ V T K +L +V AG++ +E SFVSPK + QM+D
Sbjct: 43 TMTDQAIINEVGLRDGLQNQPVTVDTATKAKLAQLLVDAGMRYLEPVSFVSPKAIPQMAD 102
Query: 311 SVDVMKNIQRVPGVNYPVLVPNLKGYETAKQCNVEEIAIFPAGSEGFSQKNLNCSVEEGL 490
+ + + + ++Y L+PNLKGY+ A+ + + + ++ F+++NL S+E+
Sbjct: 103 AAALTPLLPQGNDLHYTALIPNLKGYQLARDAGYPTVGLVLSTTDSFNERNLRMSLEQAA 162
Query: 491 RRFKQVADEAVRDGLRVRGYISCVVGCPYDGPI 589
+ + + A DG+ R YIS CPYDGP+
Sbjct: 163 QSCEAIIAAAKADGIATRTYISGAFACPYDGPV 195
>UniRef50_A3JC95 Cluster: Pyruvate carboxyltransferase; n=3;
Gammaproteobacteria|Rep: Pyruvate carboxyltransferase -
Marinobacter sp. ELB17
Length = 308
Score = 113 bits (273), Expect = 2e-24
Identities = 55/156 (35%), Positives = 91/156 (58%)
Frame = +2
Query: 143 EIRIYEVGPRDGLQNESKFVPTDIKVELISKIVAAGIKNVESASFVSPKWVKQMSDSVDV 322
+IRI EVGPRDGLQ++ K + + ++ LI +V G+KNVE+ SFVSPK V QM+ + D+
Sbjct: 2 KIRINEVGPRDGLQSQGKTLSVEDRLSLIQALVKVGLKNVEAGSFVSPKAVPQMAGTDDL 61
Query: 323 MKNIQRVPGVNYPVLVPNLKGYETAKQCNVEEIAIFPAGSEGFSQKNLNCSVEEGLRRFK 502
+ V Y LVPN+KGYE A + + + +E +QKN+ S+ + +
Sbjct: 62 FALLPERSAVRYAGLVPNMKGYELAVAAGANVVNVVLSVTETMNQKNIRMSLPQTVEVCT 121
Query: 503 QVADEAVRDGLRVRGYISCVVGCPYDGPIHPKNIAK 610
+ + +G+ V+ Y++ CP++G + P +A+
Sbjct: 122 AIIERGRCEGVEVQAYLAVAFECPFEGLVEPAVVAR 157
>UniRef50_Q2PQY9 Cluster: Hydroxymethylglutaryl-CoA lyase; n=1;
Rhodococcus sp. T104|Rep: Hydroxymethylglutaryl-CoA
lyase - Rhodococcus sp. T104
Length = 307
Score = 112 bits (269), Expect = 7e-24
Identities = 59/150 (39%), Positives = 89/150 (59%), Gaps = 2/150 (1%)
Frame = +2
Query: 146 IRIYEVGPRDGLQNESKFVPTDIKVELISKIVAAGIKNVESASFVSPKWVKQMSDSVDVM 325
++I EVGPRDG QNE + +PTD KV LI+ + AG +E ASFV P + Q++D V+V+
Sbjct: 7 VQIREVGPRDGFQNEPERIPTDDKVRLINALGRAGFTRIEVASFVRPDVIPQLADGVEVL 66
Query: 326 KNIQRVPGVNYPVLVPNLKGYETAKQC--NVEEIAIFPAGSEGFSQKNLNCSVEEGLRRF 499
+ I+ VLVPN +G E A + E+AIF + SE ++KN+N +V+E +
Sbjct: 67 ERIEVPDETKLMVLVPNSRGLENALKVRDKFHEVAIFVSASETHNKKNVNRTVDETMADN 126
Query: 500 KQVADEAVRDGLRVRGYISCVVGCPYDGPI 589
+A V +GL I+ GCP++G +
Sbjct: 127 DVMAKRIVAEGLDCAAVIATSFGCPFEGKV 156
>UniRef50_A5UPD9 Cluster: Pyruvate carboxyltransferase; n=4;
Chloroflexaceae|Rep: Pyruvate carboxyltransferase -
Roseiflexus sp. RS-1
Length = 304
Score = 112 bits (269), Expect = 7e-24
Identities = 54/154 (35%), Positives = 85/154 (55%)
Frame = +2
Query: 143 EIRIYEVGPRDGLQNESKFVPTDIKVELISKIVAAGIKNVESASFVSPKWVKQMSDSVDV 322
+I I +V PRDGLQNE + +P KV LI ++V +GI VE +FV+P+ V Q + + +V
Sbjct: 7 DITIIDVAPRDGLQNEPEILPVVTKVALIRRLVESGIPWVEIGAFVNPRQVPQQAGTTEV 66
Query: 323 MKNIQRVPGVNYPVLVPNLKGYETAKQCNVEEIAIFPAGSEGFSQKNLNCSVEEGLRRFK 502
+ + L+PN++GYE A + + + A SE +Q N SV + L F
Sbjct: 67 AMALTDGETARFTCLIPNMRGYELAVAAGMRHVRLVLAASESLNQANFKRSVSDSLADFA 126
Query: 503 QVADEAVRDGLRVRGYISCVVGCPYDGPIHPKNI 604
+A +AVRDG+ + GCP++G + P +
Sbjct: 127 HIAGQAVRDGVAFGVAVGAAFGCPFEGAVAPVRV 160
>UniRef50_A5V0V3 Cluster: Pyruvate carboxyltransferase; n=5;
Chloroflexi (class)|Rep: Pyruvate carboxyltransferase -
Roseiflexus sp. RS-1
Length = 328
Score = 111 bits (267), Expect = 1e-23
Identities = 55/148 (37%), Positives = 82/148 (55%)
Frame = +2
Query: 146 IRIYEVGPRDGLQNESKFVPTDIKVELISKIVAAGIKNVESASFVSPKWVKQMSDSVDVM 325
+ I EVGPRDGLQNE + T KV+LI ++ G+ +E +FV P V QM+D+ DV
Sbjct: 26 VSIREVGPRDGLQNEDVILTTTQKVQLIDRLADTGLTLIEVGAFVRPANVPQMADTADVF 85
Query: 326 KNIQRVPGVNYPVLVPNLKGYETAKQCNVEEIAIFPAGSEGFSQKNLNCSVEEGLRRFKQ 505
I R PGV Y +VPN G A + + +F + SE ++ N+N S+E+ L +
Sbjct: 86 AAISRRPGVVYSAIVPNAIGARRAVAAQADALQVFLSASESHNRSNVNMSIEQSLAQAAD 145
Query: 506 VADEAVRDGLRVRGYISCVVGCPYDGPI 589
+A A G+ +S GCP++G +
Sbjct: 146 IAAIAREAGVCFEAVVSVAFGCPFEGDV 173
>UniRef50_Q2GNI7 Cluster: Putative uncharacterized protein; n=1;
Chaetomium globosum|Rep: Putative uncharacterized
protein - Chaetomium globosum (Soil fungus)
Length = 595
Score = 65.7 bits (153), Expect(2) = 3e-23
Identities = 32/67 (47%), Positives = 45/67 (67%), Gaps = 3/67 (4%)
Frame = +2
Query: 416 EIAIFPAGSEGFSQKNLNCSVEEGLRRFKQVADEAVRD--GLRVRGYISCVVGCPYDG-P 586
EIA+F + +E FSQ+NLNC + L RF+ V +A +D LRVR YIS V+GCP++G
Sbjct: 394 EIAVFASATESFSQRNLNCDIATSLARFRDVI-QAAKDTHALRVRAYISVVLGCPFEGYD 452
Query: 587 IHPKNIA 607
+ P +A
Sbjct: 453 VDPHRVA 459
Score = 65.3 bits (152), Expect(2) = 3e-23
Identities = 26/51 (50%), Positives = 37/51 (72%)
Frame = +2
Query: 146 IRIYEVGPRDGLQNESKFVPTDIKVELISKIVAAGIKNVESASFVSPKWVK 298
+++ EVGPRDGLQNE + +P K+ELI ++ G+ +E+ SFVSPKW K
Sbjct: 340 VKLVEVGPRDGLQNEKRAIPLATKLELIERLAKTGLTTIEAGSFVSPKWDK 390
>UniRef50_Q189Z3 Cluster: Putative hydroxymethylglutaryl-CoA lyase;
n=3; Clostridium difficile|Rep: Putative
hydroxymethylglutaryl-CoA lyase - Clostridium difficile
(strain 630)
Length = 298
Score = 108 bits (259), Expect = 1e-22
Identities = 54/148 (36%), Positives = 93/148 (62%), Gaps = 1/148 (0%)
Frame = +2
Query: 143 EIRIYEVGPRDGLQNESKFVPTDIKVELISKIVAAGIKNVESASFVSPKWVKQMSDSVDV 322
++ I+EVGPRDG QN +F+ TD K+++I ++A+GIK +E +SFVSPK + QM D+ +V
Sbjct: 3 KVNIFEVGPRDGFQNLKEFLETDKKLKIIDGLIASGIKQLEISSFVSPKAIPQMKDAKEV 62
Query: 323 MKN-IQRVPGVNYPVLVPNLKGYETAKQCNVEEIAIFPAGSEGFSQKNLNCSVEEGLRRF 499
+++ P V LVPNL G + A +C + +I+ + SE ++KN+N + EE +
Sbjct: 63 ATYCVEKYPDVKLYALVPNLYGAKVAWECGIRDISYVISLSETHNKKNINRTHEESIDEL 122
Query: 500 KQVADEAVRDGLRVRGYISCVVGCPYDG 583
K++ + + + ++ V GCP++G
Sbjct: 123 KKIMN--TYPDMNICIGMATVFGCPFEG 148
>UniRef50_Q8ELJ7 Cluster: Hydroxymethylglutaryl-CoA lyase; n=1;
Oceanobacillus iheyensis|Rep: Hydroxymethylglutaryl-CoA
lyase - Oceanobacillus iheyensis
Length = 318
Score = 107 bits (256), Expect = 3e-22
Identities = 50/146 (34%), Positives = 83/146 (56%)
Frame = +2
Query: 152 IYEVGPRDGLQNESKFVPTDIKVELISKIVAAGIKNVESASFVSPKWVKQMSDSVDVMKN 331
I EV PRDG Q E +++PTD KVE+I + GI +E SFV PK + Q+ D+ +V+
Sbjct: 14 ICEVAPRDGFQAEPEWIPTDKKVEMIRSLAKTGITTMEVTSFVHPKAIPQLKDAEEVVSR 73
Query: 332 IQRVPGVNYPVLVPNLKGYETAKQCNVEEIAIFPAGSEGFSQKNLNCSVEEGLRRFKQVA 511
+ + ++ LVPNL G + A V+++ + + ++ S N N +V E + + +
Sbjct: 74 VHDIENLHLRALVPNLTGAQRAVNAGVKKLKLMLSATDSHSLSNANATVIEAQNKLEPII 133
Query: 512 DEAVRDGLRVRGYISCVVGCPYDGPI 589
+ A ++ +V G IS GCPY+G +
Sbjct: 134 EYANQNDTKVGGSISVAFGCPYEGKV 159
>UniRef50_A1WEM7 Cluster: Pyruvate carboxyltransferase; n=2;
Comamonadaceae|Rep: Pyruvate carboxyltransferase -
Verminephrobacter eiseniae (strain EF01-2)
Length = 332
Score = 105 bits (253), Expect = 6e-22
Identities = 55/146 (37%), Positives = 83/146 (56%)
Frame = +2
Query: 146 IRIYEVGPRDGLQNESKFVPTDIKVELISKIVAAGIKNVESASFVSPKWVKQMSDSVDVM 325
I ++EVG RDGLQ E+ FVPTD K+ LI + AG++ +E+ +FVSP+ + + D+ V+
Sbjct: 15 IALHEVGMRDGLQAETAFVPTDEKIALIDALADAGMRKIEATAFVSPQAIPALRDASAVL 74
Query: 326 KNIQRVPGVNYPVLVPNLKGYETAKQCNVEEIAIFPAGSEGFSQKNLNCSVEEGLRRFKQ 505
+ I R PGV Y LVPN G E A +E+ + + SE + NL + +
Sbjct: 75 RAIGRRPGVIYSALVPNAGGAERAIDAGADELNLVMSASESHNLANLKMTRAQSFEALSG 134
Query: 506 VADEAVRDGLRVRGYISCVVGCPYDG 583
V+ A + +RV +SC GCP +G
Sbjct: 135 VSRIARQARVRVNISLSCSFGCPMEG 160
>UniRef50_A1W9T7 Cluster: Pyruvate carboxyltransferase; n=34;
Proteobacteria|Rep: Pyruvate carboxyltransferase -
Acidovorax sp. (strain JS42)
Length = 327
Score = 101 bits (243), Expect = 1e-20
Identities = 55/151 (36%), Positives = 84/151 (55%), Gaps = 3/151 (1%)
Frame = +2
Query: 146 IRIYEVGPRDGLQNESKFVPTDIKVELISKIVAAGIKNVESASFVSPKWVKQMSDSVDVM 325
I + +VG RDGLQ E++FVPT+ K+ L++ + AG+ +E SF SP + + D+ VM
Sbjct: 13 IALCDVGLRDGLQMEAQFVPTEDKIALVNALSHAGLSKIEVTSFTSPTAIPALRDAEVVM 72
Query: 326 KNIQRVPGVNYPVLVPNLKGYETAKQCNVEEIAIFPAGSEGFSQKNLNCSVEEGLRRFKQ 505
+ I+R PGV Y LVPN +G E A + +E+ + + SE + NL + + Q
Sbjct: 73 REIERRPGVTYTALVPNARGAERAIESRTDELNLVMSVSETHNLANLRMTRAQSFAALAQ 132
Query: 506 V---ADEAVRDGLRVRGYISCVVGCPYDGPI 589
V A A + V +SCV GCP +G +
Sbjct: 133 VITMAQAAQAAQVPVNVSLSCVFGCPMEGDV 163
>UniRef50_A7D6W3 Cluster: Pyruvate carboxyltransferase; n=1;
Halorubrum lacusprofundi ATCC 49239|Rep: Pyruvate
carboxyltransferase - Halorubrum lacusprofundi ATCC
49239
Length = 314
Score = 101 bits (243), Expect = 1e-20
Identities = 53/149 (35%), Positives = 80/149 (53%)
Frame = +2
Query: 143 EIRIYEVGPRDGLQNESKFVPTDIKVELISKIVAAGIKNVESASFVSPKWVKQMSDSVDV 322
++ + E+ PRDG Q +FVPTD KVE+I + G+ +E SF PK V + D+ +V
Sbjct: 7 DVTLVEMLPRDGFQRLDEFVPTDEKVEIIDALSETGVDEIEITSFTHPKAVPTLRDADEV 66
Query: 323 MKNIQRVPGVNYPVLVPNLKGYETAKQCNVEEIAIFPAGSEGFSQKNLNCSVEEGLRRFK 502
+ I+R V Y LVPN G E A V+++ SE +S+ N N +VEE L +
Sbjct: 67 AQRIERHDDVTYRALVPNAVGMERAIDAGVDKVNALVTVSETYSEHNQNMTVEEILTGVE 126
Query: 503 QVADEAVRDGLRVRGYISCVVGCPYDGPI 589
++ + A G+ V + CPY+G I
Sbjct: 127 EIVEMAEGTGIEVEAGMGTSFYCPYEGRI 155
>UniRef50_A1HRC2 Cluster: Pyruvate carboxyltransferase; n=1;
Thermosinus carboxydivorans Nor1|Rep: Pyruvate
carboxyltransferase - Thermosinus carboxydivorans Nor1
Length = 303
Score = 100 bits (240), Expect = 2e-20
Identities = 50/151 (33%), Positives = 90/151 (59%), Gaps = 3/151 (1%)
Frame = +2
Query: 146 IRIYEVGPRDGLQNESKFVPTDIKVELISKIVAAGIKNVESASFVSPKWVKQMSDSVDVM 325
+ + EVGPRDG QN F+PT +K+++I++++AAG++ +E SFV PK + QM+D+ ++
Sbjct: 8 VEVVEVGPRDGFQNIKTFIPTAVKLQIIAQLIAAGVRKMEVTSFVHPKAIPQMADAAEIA 67
Query: 326 KNI-QRVPGVNY-PV-LVPNLKGYETAKQCNVEEIAIFPAGSEGFSQKNLNCSVEEGLRR 496
+ + ++ P+ LVPNL G + A +C + E+A + SE + N+N + ++ L
Sbjct: 68 STVCAKYQEADFVPLALVPNLVGAKNAYRCGIREVAYVISASEKHNLANINRTRDQSLVE 127
Query: 497 FKQVADEAVRDGLRVRGYISCVVGCPYDGPI 589
+ E L+VR ++ GCP+ G +
Sbjct: 128 LASITSEL--PDLKVRLDVATAFGCPFLGRV 156
>UniRef50_Q9NT06 Cluster: Putative uncharacterized protein
DKFZp434G1411; n=3; Tetrapoda|Rep: Putative
uncharacterized protein DKFZp434G1411 - Homo sapiens
(Human)
Length = 157
Score = 69.7 bits (163), Expect(2) = 2e-20
Identities = 31/61 (50%), Positives = 43/61 (70%)
Frame = +2
Query: 125 LSTVAPEIRIYEVGPRDGLQNESKFVPTDIKVELISKIVAAGIKNVESASFVSPKWVKQM 304
LS + ++I EVGPRDGLQNE VPTDIK+E I+++ G+ +E SFVS +WV Q+
Sbjct: 47 LSGLPEFVKIVEVGPRDGLQNEKVIVPTDIKIEFINRLSQTGLSVIEVTSFVSSRWVPQV 106
Query: 305 S 307
+
Sbjct: 107 A 107
Score = 51.6 bits (118), Expect(2) = 2e-20
Identities = 21/46 (45%), Positives = 32/46 (69%)
Frame = +2
Query: 416 EIAIFPAGSEGFSQKNLNCSVEEGLRRFKQVADEAVRDGLRVRGYI 553
EI++F A SE FS+KN+NCS+EE + +F++V A + RGY+
Sbjct: 112 EISVFGAASESFSKKNINCSIEESMGKFEEVVKSARHMNIPARGYL 157
>UniRef50_UPI000050F9CC Cluster: COG0119:
Isopropylmalate/homocitrate/citramalate synthases; n=1;
Brevibacterium linens BL2|Rep: COG0119:
Isopropylmalate/homocitrate/citramalate synthases -
Brevibacterium linens BL2
Length = 337
Score = 99.1 bits (236), Expect = 7e-20
Identities = 55/148 (37%), Positives = 84/148 (56%), Gaps = 2/148 (1%)
Frame = +2
Query: 146 IRIYEVGPRDGLQNESKFVPTDIKVELISKIVAAGIKNVESASFVSPKWVKQMSDSVDVM 325
+ I + RDGLQ E VPTD KV L +++AAG+K +E SFV+PK V QM+D+ +V+
Sbjct: 38 VTILDTTLRDGLQIEDAIVPTDAKVALGEQLIAAGLKEIEVGSFVNPKKVPQMADTGEVL 97
Query: 326 KNIQ--RVPGVNYPVLVPNLKGYETAKQCNVEEIAIFPAGSEGFSQKNLNCSVEEGLRRF 499
+ +Q GV++ LV NLKG + A + I + + SEG SQ N + + + +R
Sbjct: 98 QRLQSHEAEGVDFFTLVFNLKGAQRAVDAGAKNIKLVLSASEGHSQANSDAPIAQATQRL 157
Query: 500 KQVADEAVRDGLRVRGYISCVVGCPYDG 583
+ A A +G+R + CP+DG
Sbjct: 158 LEAATFAKDNGVRFDIATAVSFICPFDG 185
>UniRef50_Q1YPG1 Cluster: Hydroxymethylglutaryl-CoA lyase; n=2;
unclassified Gammaproteobacteria (miscellaneous)|Rep:
Hydroxymethylglutaryl-CoA lyase - gamma proteobacterium
HTCC2207
Length = 304
Score = 97.9 bits (233), Expect = 2e-19
Identities = 50/149 (33%), Positives = 81/149 (54%), Gaps = 1/149 (0%)
Frame = +2
Query: 152 IYEVGPRDGLQNESKFVPTDIKVELISKIVAAGIKNVESASFVSPKWVKQMSDSVDVMKN 331
I +VGPRDGLQN+ + + + +++L++ I G+ +E SFVSPK V M+ + V
Sbjct: 7 ITDVGPRDGLQNQPQVLSVEQRLQLVNAIADCGVPQIEVGSFVSPKAVPAMAGTGQVFSA 66
Query: 332 IQRVPGVNYPV-LVPNLKGYETAKQCNVEEIAIFPAGSEGFSQKNLNCSVEEGLRRFKQV 508
+ V + L+PN+KGYE A++ V+ + + S+G +QKN+ S+ E +
Sbjct: 67 LDAAEFVTPTIALIPNMKGYELARESGVKTVTMVVYASDGMAQKNVGMSMAEAELVTLDI 126
Query: 509 ADEAVRDGLRVRGYISCVVGCPYDGPIHP 595
A DG+ V I+ CP+DG P
Sbjct: 127 LKLAKEDGIEVIATIAVAFECPFDGATDP 155
>UniRef50_Q9F132 Cluster: Putative uncharacterized protein xlnI;
n=1; Pseudomonas alcaligenes|Rep: Putative
uncharacterized protein xlnI - Pseudomonas alcaligenes
Length = 305
Score = 96.3 bits (229), Expect = 5e-19
Identities = 53/151 (35%), Positives = 82/151 (54%), Gaps = 1/151 (0%)
Frame = +2
Query: 140 PEIRIYEVGPRDGLQNESKFVPTDIKVELISKIVAAGIKNVESASFVSPKWVKQMSDSVD 319
P I + EV PRDG Q+ + + T K+ +I +V+AG K VE SFV+PK V QM+D+
Sbjct: 5 PTIEVVEVSPRDGFQSICEPIETQKKISIIEDLVSAGCKRVEIGSFVNPKAVPQMADTSL 64
Query: 320 VMKNIQRVPGVNYPVLVPNLKGYETAKQCNVEEIAIFPAGSEGFSQKNLNCSVEEGLRRF 499
+ ++ LVPNLKG+E A + +V+E+A + S+ +QKN+ CS ++ +
Sbjct: 65 IAQHFGGRKDFRALALVPNLKGFERALENDVKEMAYVFSASDTHNQKNVGCSTKDSIEAL 124
Query: 500 K-QVADEAVRDGLRVRGYISCVVGCPYDGPI 589
K + + +R I CPY G I
Sbjct: 125 KVLIKTYHSEKDISLRVSIGTAFDCPYQGRI 155
>UniRef50_UPI000050F830 Cluster: COG0119:
Isopropylmalate/homocitrate/citramalate synthases; n=1;
Brevibacterium linens BL2|Rep: COG0119:
Isopropylmalate/homocitrate/citramalate synthases -
Brevibacterium linens BL2
Length = 311
Score = 94.7 bits (225), Expect = 2e-18
Identities = 48/147 (32%), Positives = 81/147 (55%)
Frame = +2
Query: 149 RIYEVGPRDGLQNESKFVPTDIKVELISKIVAAGIKNVESASFVSPKWVKQMSDSVDVMK 328
R+ EVG RDGLQ + TD K+ ++S+++AAG K +E ASF PK + Q++D+ V+
Sbjct: 9 RVVEVGLRDGLQAIDTPLSTDRKIAIVSEMIAAGFKEIEVASFAHPKVLPQLADAEAVLA 68
Query: 329 NIQRVPGVNYPVLVPNLKGYETAKQCNVEEIAIFPAGSEGFSQKNLNCSVEEGLRRFKQV 508
I R P V + LVPN +G A +C ++E+ +G + KN + + L + ++
Sbjct: 69 GIPRPPDVRFRALVPNARGALRAAKCELDELTFVVPAEDGMALKNQGTTTDGLLDQLDEI 128
Query: 509 ADEAVRDGLRVRGYISCVVGCPYDGPI 589
+ + G R+ ++C P GP+
Sbjct: 129 REVSGGAGQRLIVAVACAFFSPCYGPV 155
>UniRef50_A3JDD8 Cluster: Hydroxymethylglutaryl-CoA lyase; n=2;
Proteobacteria|Rep: Hydroxymethylglutaryl-CoA lyase -
Marinobacter sp. ELB17
Length = 312
Score = 94.3 bits (224), Expect = 2e-18
Identities = 49/150 (32%), Positives = 83/150 (55%), Gaps = 2/150 (1%)
Frame = +2
Query: 146 IRIYEVGPRDGLQNESKFVPTDIKVELISKIVAAGIKNVESASFVSPKWVKQMSDSVDVM 325
+ I EV PRDG Q+ + +PT K++ + ++ +GI +E SFVS K + QM+D +++
Sbjct: 11 VDIVEVAPRDGFQSIHELLPTAGKIQCVQALIDSGITRIEIGSFVSSKAIPQMADIGNIV 70
Query: 326 KNIQRVPGVNYPVLVPNLKGYETAKQCNVEEIAIFPAGSEGFSQKNLNCSVEEGLRRFKQ 505
G+ + LVPNLKG + A ++E+ + SE +Q N+ SV+ L K
Sbjct: 71 AAFSDHTGMRFSALVPNLKGADRALASGIKELVFVVSVSETHNQSNVRQSVDSSLDGLKT 130
Query: 506 VAD--EAVRDGLRVRGYISCVVGCPYDGPI 589
+AD + + +R+R ++ CPY+G I
Sbjct: 131 IADRLRSEKHSVRLRLDLATCFDCPYEGEI 160
>UniRef50_A3WDQ0 Cluster: 3-hydroxy-3-methylglutarate-CoA lyase;
n=2; Sphingomonadales|Rep:
3-hydroxy-3-methylglutarate-CoA lyase - Erythrobacter
sp. NAP1
Length = 309
Score = 93.1 bits (221), Expect = 5e-18
Identities = 53/164 (32%), Positives = 90/164 (54%), Gaps = 6/164 (3%)
Frame = +2
Query: 137 APEIRIYEVGPRDGLQNESKFVPTDIKVELISKIVAAGIKNVESASFVSPKWVKQMSDSV 316
AP I + EVGPRDGLQNE + VPT K++LI+ ++ G + +E ASFV P V QM+D+
Sbjct: 10 APAIELVEVGPRDGLQNEPETVPTATKLDLINAMINYGARRLEVASFVHPNRVPQMADAE 69
Query: 317 DVMKNIQRVPGVNYPVLVPN----LKGYETAK--QCNVEEIAIFPAGSEGFSQKNLNCSV 478
V++ + V + L N ++G T + + +++ S+ F KN ++
Sbjct: 70 AVIEALPDRGDVTFIGLTLNKRGIMRGLATREGGRRGIDQAGCVIVASDTFGIKNQGQTI 129
Query: 479 EEGLRRFKQVADEAVRDGLRVRGYISCVVGCPYDGPIHPKNIAK 610
+EG+ + + A +GLR + IS GCP++G + + + +
Sbjct: 130 DEGIAENRDMIRFAKAEGLRAQVTISAAFGCPFEGEVKSETVLR 173
>UniRef50_Q9AAX5 Cluster: 3-hydroxy-3-methylglutarate-CoA lyase;
n=5; Alphaproteobacteria|Rep:
3-hydroxy-3-methylglutarate-CoA lyase - Caulobacter
crescentus (Caulobacter vibrioides)
Length = 299
Score = 92.3 bits (219), Expect = 8e-18
Identities = 48/149 (32%), Positives = 81/149 (54%), Gaps = 1/149 (0%)
Frame = +2
Query: 146 IRIYEVGPRDGLQNESKFVPTDIKVELISKIVAAGIKNVESASFVSPKWVKQMSDSVDVM 325
I+I EVGPRDGLQNE + + K++LI+K+ AAG + E SFV+P V QM+ + ++M
Sbjct: 5 IQIVEVGPRDGLQNEKTVLSVEEKLDLIAKLEAAGARRTEVVSFVNPSRVPQMAGAEEIM 64
Query: 326 KNIQRVPGVNYPVLVPNLKGYETAKQCNVEEIAIFPAGSEGFSQKNLNCSVEEGLRRFKQ 505
+ + LV N++G+E +E + S+GF+ +N + ++ +
Sbjct: 65 AALPADLVHSRIGLVLNMRGWERCVSTGCDEANVVVCASDGFATRNQGSTTQQQVETLAA 124
Query: 506 VAD-EAVRDGLRVRGYISCVVGCPYDGPI 589
+ + +A G + IS GCP+DG +
Sbjct: 125 IVERQAAEGGPPITATISVAFGCPFDGEV 153
>UniRef50_Q2S361 Cluster: 3-hydroxy-3-methylglutaryl-CoA lyase; n=2;
Bacteria|Rep: 3-hydroxy-3-methylglutaryl-CoA lyase -
Salinibacter ruber (strain DSM 13855)
Length = 307
Score = 91.9 bits (218), Expect = 1e-17
Identities = 51/150 (34%), Positives = 78/150 (52%), Gaps = 2/150 (1%)
Frame = +2
Query: 146 IRIYEVGPRDGLQNESKFVPTDIKVELISKIVAAGIKNVESASFVSPKWVKQMSDSVDVM 325
+ + +VGPRDG Q E +F+PTD KV++I+ + AG+ ++ SFV PKWV QM D+ V
Sbjct: 7 VALCDVGPRDGFQFEEQFIPTDRKVDVITALADAGLPRIQVTSFVHPKWVPQMKDAEAVC 66
Query: 326 KNIQRVPGVNYPVLVPNLKGYETAKQCNVEEIAIFPAGSEGFSQKNLNCSVEEGLRRFKQ 505
+ V Y L N +G E A + ++ + A + SQ N N +V+E + +
Sbjct: 67 SRLPDRADVTYAGLALNQRGLERAHAAGLSQVDLSIATHDRHSQDNANRTVDEAVAQADD 126
Query: 506 VADEAVRDGLRVRGYISCVVG--CPYDGPI 589
+ A GL V+ V G P D P+
Sbjct: 127 MVRYAHEHGLAVQMGFQTVFGYQAPGDTPL 156
>UniRef50_Q1EXX3 Cluster: Pyruvate carboxyltransferase; n=1;
Clostridium oremlandii OhILAs|Rep: Pyruvate
carboxyltransferase - Clostridium oremlandii OhILAs
Length = 306
Score = 91.5 bits (217), Expect = 1e-17
Identities = 48/160 (30%), Positives = 86/160 (53%), Gaps = 3/160 (1%)
Frame = +2
Query: 134 VAPEIRIYEVGPRDGLQNESKFVPTDIKVELISKIVAAGIKNVESASFVSPKWVKQMSDS 313
+ + I EV PRDG QN F+ T+ K+ ++ +++ A K +E SFVSPK + QM+D+
Sbjct: 3 IPKSVEILEVCPRDGFQNVKDFIATEDKIAIVERLIDANFKRIELGSFVSPKAIPQMADT 62
Query: 314 VDVM---KNIQRVPGVNYPVLVPNLKGYETAKQCNVEEIAIFPAGSEGFSQKNLNCSVEE 484
+V+ K + + LVPN +G E+A V++I + SE ++ N+N +V E
Sbjct: 63 KEVVAAAKQYAVDQDIKFVALVPNARGVESAIAAGVDQITYVISASESHNKANVNRTVAE 122
Query: 485 GLRRFKQVADEAVRDGLRVRGYISCVVGCPYDGPIHPKNI 604
+ +++ + E D + R ++ GCP+ + + I
Sbjct: 123 SMEQYEALIKEYKGD-IDFRLGLATTFGCPFGDEVKIERI 161
>UniRef50_Q5WKL8 Cluster: Hydroxymethylglutaryl-CoA lyase; n=1;
Bacillus clausii KSM-K16|Rep: Hydroxymethylglutaryl-CoA
lyase - Bacillus clausii (strain KSM-K16)
Length = 309
Score = 90.6 bits (215), Expect = 2e-17
Identities = 53/153 (34%), Positives = 80/153 (52%)
Frame = +2
Query: 146 IRIYEVGPRDGLQNESKFVPTDIKVELISKIVAAGIKNVESASFVSPKWVKQMSDSVDVM 325
+ I EVGPRDGLQNE + + K+E++ +GI +E+ SFV+ K V M+D+ +VM
Sbjct: 13 VEICEVGPRDGLQNEQVRLSVEQKIEMMEHAARSGISKIEAVSFVNKKLVPAMADAEEVM 72
Query: 326 KNIQRVPGVNYPVLVPNLKGYETAKQCNVEEIAIFPAGSEGFSQKNLNCSVEEGLRRFKQ 505
R GV L + G A Q ++ + I + S+ F+++N N +V EGL
Sbjct: 73 AAWHRREGVRIAGLALSRSGITRALQTPIDVLHITISASDAFNKRNANKTVAEGLSDLLP 132
Query: 506 VADEAVRDGLRVRGYISCVVGCPYDGPIHPKNI 604
V EA L V IS GCP+ G + + +
Sbjct: 133 VVGEA-STHLPVVTVISTSFGCPFSGDVQMETV 164
>UniRef50_Q0S6H7 Cluster: Possible hydroxymethylglutaryl-CoA lyase;
n=2; Actinomycetales|Rep: Possible
hydroxymethylglutaryl-CoA lyase - Rhodococcus sp.
(strain RHA1)
Length = 289
Score = 89.8 bits (213), Expect = 4e-17
Identities = 53/156 (33%), Positives = 81/156 (51%), Gaps = 1/156 (0%)
Frame = +2
Query: 146 IRIYEVGPRDGLQNESKFVPTDIKVELISKIVAAGIKNVESASFVSPKWVKQMSDSVDVM 325
+ I +V RDGLQ+E V TD K+ + +VAAG+K++E+ASFVSP V QM+D+ DV+
Sbjct: 3 VTITDVVLRDGLQDEDVVVSTDHKIVVADALVAAGVKHIEAASFVSPTRVPQMADADDVI 62
Query: 326 KNIQRV-PGVNYPVLVPNLKGYETAKQCNVEEIAIFPAGSEGFSQKNLNCSVEEGLRRFK 502
+ R P V Y L N +G A ++EI + + S G S N + +E L
Sbjct: 63 ARLPRTDPSVTYSALALNPRGVHRAIATGIDEIQVVTSASAGHSTANTGRNPDEALHGLA 122
Query: 503 QVADEAVRDGLRVRGYISCVVGCPYDGPIHPKNIAK 610
+ + G +S CP++G I P + +
Sbjct: 123 EALQK--YPDRSFLGGVSTAFVCPFEGIIAPAALVR 156
>UniRef50_Q0UL76 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 384
Score = 88.2 bits (209), Expect = 1e-16
Identities = 42/93 (45%), Positives = 65/93 (69%), Gaps = 5/93 (5%)
Frame = +2
Query: 128 STVAPEIRIYEVGPRDGLQNESKFVPTDIKVELISKIVAAGIKNVESASFVSPKWVKQMS 307
S+ A +RI EVGPRDGLQNE + +P K+EL+ ++ +G++ +E+ SFVSPKWV QM+
Sbjct: 29 SSRADHVRIVEVGPRDGLQNEKQSIPVATKIELVERLAQSGLEYIEAGSFVSPKWVPQMA 88
Query: 308 DSVD----VMKNIQRVP-GVNYPVLVPNLKGYE 391
+S + V+KN ++P V Y L+PN++G +
Sbjct: 89 NSSEILEHVLKNKSKLPQNVVYQWLLPNVRGLD 121
Score = 78.2 bits (184), Expect = 1e-13
Identities = 35/94 (37%), Positives = 53/94 (56%), Gaps = 1/94 (1%)
Frame = +2
Query: 332 IQRVPGVNYPVLVPNLKGYETAKQCNVEEIAIFPAGSEGFSQKNLNCSVEEGLRRFKQVA 511
++ P +N PN G + E++IF A +E F++KN NCS+ E L RFK +
Sbjct: 146 VEDSPALNTSSQDPNAMGSTLSSSGTRHEVSIFTAATESFTRKNTNCSIAESLERFKPIM 205
Query: 512 DEAVRDGLRVRGYISCVVGCPYDGP-IHPKNIAK 610
+ + G VR YIS +GCPY+GP + P +A+
Sbjct: 206 NRGMEMGFNVRAYISVALGCPYEGPNVDPHRVAE 239
>UniRef50_Q89GI1 Cluster: Bll6364 protein; n=1; Bradyrhizobium
japonicum|Rep: Bll6364 protein - Bradyrhizobium
japonicum
Length = 311
Score = 87.4 bits (207), Expect = 2e-16
Identities = 48/156 (30%), Positives = 77/156 (49%), Gaps = 3/156 (1%)
Frame = +2
Query: 152 IYEVGPRDGLQNESKFVPTDIKVELISKIVAAGIKNVESASFVSPKWVKQMSDSVDVMKN 331
+ EVGPRDGLQ +PT+ K+ ++VAAGI +E SFV PK + Q D+ +V +
Sbjct: 7 VREVGPRDGLQMVGTILPTERKLAWCRRVVAAGIHEIEVTSFVPPKLIPQFGDAEEVARG 66
Query: 332 IQRVPGVNYPVLVPNLKGYETAKQCNVEEIAIFPAGSEGFSQKNLNCSVEEGLRRFKQVA 511
+ G LVPNL+G E A V ++ + SE + N+ + E+ L F ++
Sbjct: 67 AMAIAGCRPSALVPNLRGAERAFALGVPQVNYVLSASEQHNLANVRRTTEQSLEDFARIV 126
Query: 512 ---DEAVRDGLRVRGYISCVVGCPYDGPIHPKNIAK 610
D+ V + + I+ GC G + + +
Sbjct: 127 AARDQRVGAPIALGAGIATAFGCTISGAVSNSRVVE 162
>UniRef50_Q120B4 Cluster: Pyruvate carboxyltransferase; n=3;
Proteobacteria|Rep: Pyruvate carboxyltransferase -
Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 317
Score = 87.4 bits (207), Expect = 2e-16
Identities = 51/158 (32%), Positives = 80/158 (50%), Gaps = 3/158 (1%)
Frame = +2
Query: 125 LSTVAPEIRIYEVGPRDGLQNESKFVPTDIKVELISKIVAAGIKNVESASFVSPKWVKQM 304
+S + + +E GPR+G Q E K + LI + A+G+K ++ ASFVSP+ V QM
Sbjct: 1 MSKLPTSVEFHEEGPREGFQMEPKTYSLADRAALIDALAASGLKQIQVASFVSPRAVPQM 60
Query: 305 SDSVDVMKNIQRVPGVNYPVLVPNLKGYETAKQCNVEEI--AIFPAGSEGFSQKNLNCSV 478
+D+ ++ I + PG Y L N G++ A+ C ++ + +E FSQ+N NCSV
Sbjct: 61 ADTAELFAAIAKRPGTRYTALWLNDNGFDRARACEQVDLDGKLMFYTTEPFSQRNNNCSV 120
Query: 479 EEGLRRFKQVADEAVRDGLRV-RGYISCVVGCPYDGPI 589
R D V G+ V + Y+ GC G +
Sbjct: 121 AGMRERQLGWLDRYVALGIPVEKAYVITAFGCNLGGAV 158
>UniRef50_A5P2D8 Cluster: Hydroxymethylglutaryl-CoA lyase; n=3;
Alphaproteobacteria|Rep: Hydroxymethylglutaryl-CoA lyase
- Methylobacterium sp. 4-46
Length = 308
Score = 87.4 bits (207), Expect = 2e-16
Identities = 45/148 (30%), Positives = 79/148 (53%)
Frame = +2
Query: 146 IRIYEVGPRDGLQNESKFVPTDIKVELISKIVAAGIKNVESASFVSPKWVKQMSDSVDVM 325
+ I EVGPRDG Q F+PT+ K+E++ ++VAAG++ +E SFVS + QM D+ +V+
Sbjct: 6 VEIVEVGPRDGYQGIGPFIPTERKIEILGRLVAAGLRRIEIGSFVSATALPQMRDTPEVL 65
Query: 326 KNIQRVPGVNYPVLVPNLKGYETAKQCNVEEIAIFPAGSEGFSQKNLNCSVEEGLRRFKQ 505
R PG+ VLVP+ + A + + SE ++ N+ S E + +
Sbjct: 66 AACARFPGLEPQVLVPSERRGRDAVAAGARRLVFVLSVSEAHNRNNVRRSPGESADEYDR 125
Query: 506 VADEAVRDGLRVRGYISCVVGCPYDGPI 589
+ A+ + +R ++ CP++G +
Sbjct: 126 LL-RAIPGEVAIRLDLATAFDCPFEGRV 152
>UniRef50_Q122Z2 Cluster: Pyruvate carboxyltransferase; n=64;
Proteobacteria|Rep: Pyruvate carboxyltransferase -
Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 729
Score = 87.0 bits (206), Expect = 3e-16
Identities = 47/157 (29%), Positives = 83/157 (52%), Gaps = 2/157 (1%)
Frame = +2
Query: 146 IRIYEVGPRDGLQNESKFVPTDIKVELISKIVAAGIKNVESASFVSPKWVKQMSDSVDVM 325
+ I EVGPRDGLQ+ +PT K+ I + AG++ +E ASFV + + QM+D+ +V+
Sbjct: 10 VLISEVGPRDGLQSVKATMPTADKLRWIDALYKAGVREIEVASFVPARLLPQMADAAEVV 69
Query: 326 KNIQRVPGVNYPVLVPNLKGYETAKQCNVEEIAIFPAGSEGFSQKNLNCSVEEGLRRFKQ 505
++ +PG+ LVPN +G E A V ++ + + S S N+ + EE + +
Sbjct: 70 RHAITLPGLTVMALVPNRRGAEAALAAGVHKLTMPVSASAAHSLANVRKTREEMVEEVRA 129
Query: 506 VAD--EAVRDGLRVRGYISCVVGCPYDGPIHPKNIAK 610
++D + +R+ IS GC G + ++ +
Sbjct: 130 ISDLRRDLAPHVRLEAAISTAFGCTLQGEVPEDDVIR 166
>UniRef50_A1T6B5 Cluster: Pyruvate carboxyltransferase; n=6;
Mycobacterium|Rep: Pyruvate carboxyltransferase -
Mycobacterium vanbaalenii (strain DSM 7251 / PYR-1)
Length = 301
Score = 86.6 bits (205), Expect = 4e-16
Identities = 44/160 (27%), Positives = 82/160 (51%)
Frame = +2
Query: 125 LSTVAPEIRIYEVGPRDGLQNESKFVPTDIKVELISKIVAAGIKNVESASFVSPKWVKQM 304
+S + + I +V RDGLQ E +P K+EL++ I A G++ +E+ +FVSP V +
Sbjct: 1 MSELPGHVDIRDVSLRDGLQIEDP-IPLSAKLELLAAIAATGVREMEATAFVSPSKVPAL 59
Query: 305 SDSVDVMKNIQRVPGVNYPVLVPNLKGYETAKQCNVEEIAIFPAGSEGFSQKNLNCSVEE 484
+D+ D+ ++ P + + LV + G + A + I + ++G S+ N+ S E
Sbjct: 60 ADAADLAAELRNFPDIEFSALVASPNGAKRAIAAGLRSIEYVVSAADGHSRANVGRSSAE 119
Query: 485 GLRRFKQVADEAVRDGLRVRGYISCVVGCPYDGPIHPKNI 604
+ ++ A G+ V ++ CP+DGP P+ +
Sbjct: 120 ATAQIPEIVAIAHDSGVSVEVIVATAWDCPFDGPTAPQRV 159
>UniRef50_Q5SI54 Cluster: Hydroxymethylglutaryl-CoA lyase like
protein; n=2; Thermus thermophilus|Rep:
Hydroxymethylglutaryl-CoA lyase like protein - Thermus
thermophilus (strain HB8 / ATCC 27634 / DSM 579)
Length = 286
Score = 85.0 bits (201), Expect = 1e-15
Identities = 52/142 (36%), Positives = 76/142 (53%), Gaps = 2/142 (1%)
Frame = +2
Query: 167 PRDGLQNESKFVPTDIKVELISKIVAAGIKNVESASFVSPKWVKQMSDSVDVMKNIQRVP 346
PRD Q S+F+PT+ KV +++++ AG +++ SFVSPKWV QM D+ +V+K +
Sbjct: 11 PRDAWQGFSRFIPTEEKVAFLNELLEAGFAHLDLTSFVSPKWVPQMQDAEEVLKALPPPN 70
Query: 347 GVNYPVLVPNLKGYETAKQC-NVEEIAIFPAGSEGFSQKNLNCSVEEGLRRFKQVADEAV 523
G Y +V N KG E A N+ + + SE F Q+N N S+E + +
Sbjct: 71 GRTYLAIVANEKGLERALAAPNLTHVGYPFSLSETFQQRNTNRSIEASWPLVGAMVERTE 130
Query: 524 -RDGLRVRGYISCVVGCPYDGP 586
R GL V Y+S G PY P
Sbjct: 131 GRLGLVV--YLSMAFGNPYGDP 150
>UniRef50_Q0FWC0 Cluster: Putative hydroxymethylglutaryl-CoA lyase;
n=1; Roseovarius sp. HTCC2601|Rep: Putative
hydroxymethylglutaryl-CoA lyase - Roseovarius sp.
HTCC2601
Length = 337
Score = 82.2 bits (194), Expect = 9e-15
Identities = 48/157 (30%), Positives = 81/157 (51%), Gaps = 2/157 (1%)
Frame = +2
Query: 125 LSTVAPEIRIYEVGPRDGLQNESKFVPTDIKVELISKIVAAGIKNVESASFVSPKWVKQM 304
+S + ++ I E G R+G Q+E +PT K+ LI + G+ ++ ASFV+PK V QM
Sbjct: 25 MSELPSKVHIVEEGAREGFQSEPAGIPTSEKIRLIEALAETGVPEIDCASFVNPKVVPQM 84
Query: 305 SDSVDVMKNIQRVPGVNYPVLVPNLKGYETAKQCNVEEIAIFP-AGSEGFSQKNLNCSVE 481
+D + + I++ GV Y + N KG+ A + + A+ + S+ F +N N + E
Sbjct: 85 ADVAQIAEGIRKREGVTYGCMWLNAKGFLQAAESGLSLPALTSGSASDTFLARNNNATPE 144
Query: 482 EGLRRFKQVADEAVRDGL-RVRGYISCVVGCPYDGPI 589
+ L +++ GL R Y+ GC Y+G I
Sbjct: 145 KQLEGQRKLRALYTEHGLGRGPVYLFTAFGCNYEGDI 181
>UniRef50_UPI0000510140 Cluster: COG0119:
Isopropylmalate/homocitrate/citramalate synthases; n=1;
Brevibacterium linens BL2|Rep: COG0119:
Isopropylmalate/homocitrate/citramalate synthases -
Brevibacterium linens BL2
Length = 314
Score = 81.8 bits (193), Expect = 1e-14
Identities = 46/158 (29%), Positives = 79/158 (50%), Gaps = 5/158 (3%)
Frame = +2
Query: 146 IRIYEVGPRDGLQNESKFVPTDIKVELISKIVAAGIKNVESASFVSPKWVKQMSDSVDVM 325
+ I E RDGLQ+E++FV T K+ + V G K +E+ S+ P V +D+ D++
Sbjct: 5 VSINECFARDGLQHETEFVATRDKLAALESFVRVGFKRIEATSYSHPAQVPAFTDASDLL 64
Query: 326 KNIQRVPGVNYPVLVPNLKGYETAKQ-----CNVEEIAIFPAGSEGFSQKNLNCSVEEGL 490
+ R G + PN + + A VEEI++ + SE SQ NL + E
Sbjct: 65 LKLPRPEGTAFKATCPNQRAVQRALADHDAGIGVEEISLLTSASESHSQVNLRATRNEQW 124
Query: 491 RRFKQVADEAVRDGLRVRGYISCVVGCPYDGPIHPKNI 604
+ +++A A + + G +S GCP++G + P+ +
Sbjct: 125 HKVEEMAALA-KVAFTLVGVVSVAFGCPFEGTVDPQTV 161
>UniRef50_A1UDB1 Cluster: Pyruvate carboxyltransferase; n=6;
Actinomycetales|Rep: Pyruvate carboxyltransferase -
Mycobacterium sp. (strain KMS)
Length = 301
Score = 80.2 bits (189), Expect = 4e-14
Identities = 45/160 (28%), Positives = 78/160 (48%)
Frame = +2
Query: 125 LSTVAPEIRIYEVGPRDGLQNESKFVPTDIKVELISKIVAAGIKNVESASFVSPKWVKQM 304
+S + ++ I EV RDGLQ E +P K+EL+ +VA G++ VE+ +FVSP V +
Sbjct: 1 MSDLPAKVDIREVSLRDGLQIEQP-IPLSAKLELLEAVVATGVREVEATAFVSPSKVPAL 59
Query: 305 SDSVDVMKNIQRVPGVNYPVLVPNLKGYETAKQCNVEEIAIFPAGSEGFSQKNLNCSVEE 484
+D+ ++ + R V + LV + G + A + I + ++ S+ N+ S E
Sbjct: 60 ADAAELAAELGRFDQVEFSALVASPNGAKRAIAAGLRSIEYVVSAADSHSRANVGRSSME 119
Query: 485 GLRRFKQVADEAVRDGLRVRGYISCVVGCPYDGPIHPKNI 604
+ + A V I+ CP+DGP P+ +
Sbjct: 120 SVAAIPDIVAIAHDSSATVEVIIATAWDCPFDGPTPPQRV 159
>UniRef50_Q1IRS1 Cluster: Hydroxymethylglutaryl-CoA lyase; n=1;
Acidobacteria bacterium Ellin345|Rep:
Hydroxymethylglutaryl-CoA lyase - Acidobacteria
bacterium (strain Ellin345)
Length = 290
Score = 78.2 bits (184), Expect = 1e-13
Identities = 48/149 (32%), Positives = 80/149 (53%), Gaps = 1/149 (0%)
Frame = +2
Query: 134 VAPEIRIYEVGPRDGLQNESKFVPTDIKVELISKIVAAGIKNVESASFVSPKWVKQMSDS 313
+A ++I E PRD Q +PT++KV+ + ++V+AG K++++ SFVSP+ V QM+DS
Sbjct: 1 MADTVKIIEC-PRDAWQGLKGQIPTELKVKYLQELVSAGFKHIDAVSFVSPRAVPQMADS 59
Query: 314 VDVMKNIQRVPGVNYPVLVPNLKGYETAKQCNVEEIAIFP-AGSEGFSQKNLNCSVEEGL 490
+V+K + V +V N KG + A FP + S F + N N ++EE
Sbjct: 60 EEVLKELDPPDDVEIIGIVVNEKGADRAIATEAVRTLGFPYSFSPTFLKNNQNQTLEENA 119
Query: 491 RRFKQVADEAVRDGLRVRGYISCVVGCPY 577
++V ++ + + YIS G PY
Sbjct: 120 EVLEKVVEKQRSADMDLVVYISMAFGNPY 148
>UniRef50_A6EGU7 Cluster: Hydroxymethylglutaryl-CoA lyase like
protein; n=1; Pedobacter sp. BAL39|Rep:
Hydroxymethylglutaryl-CoA lyase like protein -
Pedobacter sp. BAL39
Length = 303
Score = 78.2 bits (184), Expect = 1e-13
Identities = 49/160 (30%), Positives = 76/160 (47%), Gaps = 2/160 (1%)
Frame = +2
Query: 104 NNFLQRSLSTVAPEIRIYEVGPRDGLQNESKFVPTDIKVELISKIVAAGIKNVESASFVS 283
+N + S P ++I E PRD +Q F+ TDIKV ++K++ G ++ SFVS
Sbjct: 6 SNKVNPGSSAENPAVKIIEC-PRDAMQGIHNFIDTDIKVAYLNKLLKVGFDTIDFGSFVS 64
Query: 284 PKWVKQMSDSVDVMKNIQ-RVPGVNYPVLVPNLKGYETAKQCNVEEIAIFPAG-SEGFSQ 457
PK + Q+ D+ +V+ ++ +V NLKG + A FP SE F Q
Sbjct: 65 PKAIPQLRDTAEVLSKLELNDTSSKLLAIVANLKGVQEAATHQEITYLGFPFSISETFQQ 124
Query: 458 KNLNCSVEEGLRRFKQVADEAVRDGLRVRGYISCVVGCPY 577
+N N S+ + KQ+ + R Y+S G PY
Sbjct: 125 RNTNASITQSFDTVKQMLEICDRANKEAVVYLSMGFGNPY 164
>UniRef50_Q7VSS8 Cluster: Putative hydroxymethylglutaryl-CoA lyase;
n=5; Proteobacteria|Rep: Putative
hydroxymethylglutaryl-CoA lyase - Bordetella pertussis
Length = 335
Score = 76.2 bits (179), Expect = 6e-13
Identities = 47/153 (30%), Positives = 78/153 (50%), Gaps = 5/153 (3%)
Frame = +2
Query: 146 IRIYEVGPRDGLQNESKFVPTDIKVELISKIVAAGIKNVESASFVSPKWVKQMSDSVDVM 325
+ +E GPR+G Q+E P +V L+ + A G+K ++ ASFV+P+ V M+D+ ++
Sbjct: 15 VEFHEEGPREGFQSEKTLYPLASRVALVDALTATGLKKIQVASFVNPRMVPAMADAAELF 74
Query: 326 KNIQRVPGVNYPVLVPNLKGYE-TAKQCNVE-EIAIFPAGSEGFSQKNLNCSVEEGLRRF 499
I++ GV + L N KG E A V+ + + SE FS N CS ++ +R
Sbjct: 75 GAIRKKSGVRHTALWLNAKGIEKAAATAGVDLDGKMMLYASEAFSWSNNGCSAKDQQQR- 133
Query: 500 KQVADEAVRDGLRV---RGYISCVVGCPYDGPI 589
Q+ A+ D L + Y++ GC G +
Sbjct: 134 -QLEWLAIYDRLNLPLEAVYVATAFGCQMQGEV 165
>UniRef50_A3I2Z1 Cluster: Hydroxymethylglutaryl-CoA lyase like
protein; n=2; Flexibacteraceae|Rep:
Hydroxymethylglutaryl-CoA lyase like protein -
Algoriphagus sp. PR1
Length = 284
Score = 75.8 bits (178), Expect = 8e-13
Identities = 47/150 (31%), Positives = 75/150 (50%), Gaps = 2/150 (1%)
Frame = +2
Query: 167 PRDGLQNESKFVPTDIKVELISKIVAAGIKNVESASFVSPKWVKQMSDSVDVMKNIQ-RV 343
PRD +Q F+ T +K I++++ G ++ SFVSPK V Q+ D+ +V+ +
Sbjct: 8 PRDAMQGIPHFIDTAVKAAYINQLLEIGFDTIDFGSFVSPKAVPQLRDTEEVLGLLDLHH 67
Query: 344 PGVNYPVLVPNLKGYETAKQCNVEEIAIFPAG-SEGFSQKNLNCSVEEGLRRFKQVADEA 520
+V NL+G E A + + FP SE F QKN N S+ E L+ +++ +
Sbjct: 68 AKSKLLAIVANLRGAEDASHFDEIDYLGFPLSVSETFQQKNTNRSISEALKTVEEIQNLC 127
Query: 521 VRDGLRVRGYISCVVGCPYDGPIHPKNIAK 610
G + Y+S G PYD P+ IA+
Sbjct: 128 EVKGKTLVTYLSMGFGNPYDEAYSPELIAE 157
>UniRef50_Q89WI9 Cluster: Blr0698 protein; n=1; Bradyrhizobium
japonicum|Rep: Blr0698 protein - Bradyrhizobium
japonicum
Length = 315
Score = 74.9 bits (176), Expect = 1e-12
Identities = 52/167 (31%), Positives = 80/167 (47%), Gaps = 5/167 (2%)
Frame = +2
Query: 125 LSTVAPEIRIY--EVGPRDGLQNESKFVPTDIKVELISKIVAAGIKNVESASFVSPKWVK 298
+ T+ P R+ EVG RDGLQ KF T+ K + + AAG+++ E SF+ K
Sbjct: 4 IETIYPSDRVSLREVGLRDGLQLVKKFPSTEAKQRWVREEYAAGVRHFEVGSFLPAKTFP 63
Query: 299 QMSDSVDVMKNIQRVPGVNYPVLVPNLKGYETAKQCNVEEIAIFPAGSEGFSQKNLNCSV 478
Q D DV+ + +PG + L N +G A + V EIA + +E SQ N + S
Sbjct: 64 QFVDVRDVIGAVANLPGAHGIALALNERGVNEALESGVGEIASVVSATEEHSQANAHRSR 123
Query: 479 EEGL---RRFKQVADEAVRDGLRVRGYISCVVGCPYDGPIHPKNIAK 610
+ + RR ++ D + L V IS +GC G + P + +
Sbjct: 124 DSAIANVRRLCEMRDASSHKPL-VNAAISMALGCSITGAVDPAEVLR 169
>UniRef50_Q4AF29 Cluster: HMG-CoA lyase-like; n=1; Chlorobium
phaeobacteroides BS1|Rep: HMG-CoA lyase-like -
Chlorobium phaeobacteroides BS1
Length = 336
Score = 74.9 bits (176), Expect = 1e-12
Identities = 45/160 (28%), Positives = 83/160 (51%), Gaps = 12/160 (7%)
Frame = +2
Query: 143 EIRIYEVGPRDGLQNESKFVPTDIKVELISKIVAAGIKNVESASFVSPKWVKQMSDSVDV 322
++ I ++ RDG Q+E K+VPT+ K+ ++ +++ AG+K++E +F +PK + Q D+ +
Sbjct: 6 KVVIGDITVRDGFQHEEKYVPTEAKLWVLEELILAGVKHLEVTNFGNPKGMPQFKDADKL 65
Query: 323 MKNIQR-------VPGVNYPVLVPNLKGYETAKQCNVE-----EIAIFPAGSEGFSQKNL 466
K I+ +P V+ + + E A + E I + + SE +KN
Sbjct: 66 FKGIRNSKRVSHLLPDVSLTAVTIRERAIERAIEAKKEGYGPDRILLMVSTSESHQKKNS 125
Query: 467 NCSVEEGLRRFKQVADEAVRDGLRVRGYISCVVGCPYDGP 586
S+ E + ++ A GL+V G +S + GCP +GP
Sbjct: 126 GLSLAEYWKMAEKYIPLAQDAGLKVNGTVSTIWGCPIEGP 165
>UniRef50_A6R9V0 Cluster: Putative uncharacterized protein; n=4;
Eurotiomycetidae|Rep: Putative uncharacterized protein -
Ajellomyces capsulatus NAm1
Length = 433
Score = 70.5 bits (165), Expect = 3e-11
Identities = 29/66 (43%), Positives = 44/66 (66%), Gaps = 1/66 (1%)
Frame = +2
Query: 416 EIAIFPAGSEGFSQKNLNCSVEEGLRRFKQVADEAVRDGLRVRGYISCVVGCPYDGP-IH 592
EI++F A +E FS+ N NC++EE L R + + A +RVRGY+S +GCPY+GP +
Sbjct: 100 EISLFAAATEAFSKANTNCTIEESLERIRPIVALAKEKNIRVRGYVSVALGCPYEGPDVS 159
Query: 593 PKNIAK 610
P +A+
Sbjct: 160 PHKVAE 165
>UniRef50_Q5ARE9 Cluster: Putative uncharacterized protein; n=1;
Emericella nidulans|Rep: Putative uncharacterized
protein - Emericella nidulans (Aspergillus nidulans)
Length = 408
Score = 70.1 bits (164), Expect = 4e-11
Identities = 30/59 (50%), Positives = 43/59 (72%)
Frame = +2
Query: 134 VAPEIRIYEVGPRDGLQNESKFVPTDIKVELISKIVAAGIKNVESASFVSPKWVKQMSD 310
+ P++ I EV PRDGLQN +F+PT+IKV LI ++ G++ +E AS VSPK V Q++D
Sbjct: 33 IEPQVHIVEVSPRDGLQNIPEFIPTEIKVALIRRLAGTGLQTIEIASVVSPKVVPQLAD 91
Score = 62.1 bits (144), Expect = 1e-08
Identities = 37/116 (31%), Positives = 60/116 (51%), Gaps = 5/116 (4%)
Frame = +2
Query: 242 AAGIKNVESASFVSPKWVKQMSDSVDVMKNIQRVPGVNYPVLVPNLKGYET----AKQCN 409
+A + ES S S + + ++ G P+L+PNLKG + +
Sbjct: 114 SASESDSESESESSQQSESSFESETEFELELEPREGFCLPILLPNLKGLSLLLSHSPRPP 173
Query: 410 VEEIAIFPAGSEGFSQKNLNCSVEEGLRRFKQVADEAVRDGL-RVRGYISCVVGCP 574
+ I +F + + FS +N+NCSV++GL R ++V A + G+ RVRGYISC+ P
Sbjct: 174 IRSICVFISATAPFSHRNINCSVDDGLLRAREVTVAAKKAGIPRVRGYISCIFTDP 229
>UniRef50_Q5KLA2 Cluster: Putative uncharacterized protein; n=1;
Filobasidiella neoformans|Rep: Putative uncharacterized
protein - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 529
Score = 68.5 bits (160), Expect = 1e-10
Identities = 36/93 (38%), Positives = 51/93 (54%), Gaps = 11/93 (11%)
Frame = +2
Query: 350 VNYPVLVPNLKGYETAKQCNVE-----------EIAIFPAGSEGFSQKNLNCSVEEGLRR 496
V+YPVLVPN++G + + E EIA+F + +E FSQ N + + + L
Sbjct: 275 VHYPVLVPNMRGLDNLIKLQEEWSSKGLPALTDEIAVFVSATEAFSQANNHAPISKVLDS 334
Query: 497 FKQVADEAVRDGLRVRGYISCVVGCPYDGPIHP 595
V ++A RVRGY+SCV+ CPY GP P
Sbjct: 335 LPSVINKAKSHRFRVRGYVSCVITCPYSGPTDP 367
Score = 67.3 bits (157), Expect = 3e-10
Identities = 29/61 (47%), Positives = 45/61 (73%), Gaps = 1/61 (1%)
Frame = +2
Query: 146 IRIYEVGPRDGLQN-ESKFVPTDIKVELISKIVAAGIKNVESASFVSPKWVKQMSDSVDV 322
+RI +V PRDGLQN + K VPT++K EL+ +++ AG++N+E SFV WV QM+D+ +
Sbjct: 167 VRIVDVSPRDGLQNLKGKPVPTEVKRELVERLLEAGVRNIEVGSFVRSDWVPQMADTPQL 226
Query: 323 M 325
+
Sbjct: 227 L 227
>UniRef50_A4C110 Cluster: Hydroxymethylglutaryl-CoA lyase like
protein; n=15; Bacteroidetes|Rep:
Hydroxymethylglutaryl-CoA lyase like protein -
Polaribacter irgensii 23-P
Length = 290
Score = 65.3 bits (152), Expect = 1e-09
Identities = 42/150 (28%), Positives = 71/150 (47%), Gaps = 3/150 (2%)
Frame = +2
Query: 146 IRIYEVGPRDGLQN-ESKFVPTDIKVELISKIVAAGIKNVESASFVSPKWVKQMSDSVDV 322
++I E PRD +Q +S F+ T+ K I+ ++ G ++ SFVSPK + QM D+ V
Sbjct: 4 VKIIEC-PRDAMQGIKSHFISTEKKALYINALLTVGFDTIDFGSFVSPKAIPQMRDTAAV 62
Query: 323 MKNIQ-RVPGVNYPVLVPNLKGYETAKQCNVEEIAIFPAG-SEGFSQKNLNCSVEEGLRR 496
+ ++ ++ N++G E A Q +P SE F +N + ++ E +
Sbjct: 63 LSKLELSTTESKLLAIIANVRGAEQAAQFEEINYLGYPFSISENFQMRNTHKTIAESIAA 122
Query: 497 FKQVADEAVRDGLRVRGYISCVVGCPYDGP 586
++ A R V Y+S G PY P
Sbjct: 123 LDEILQIADRSKKEVVAYMSMGFGNPYGDP 152
>UniRef50_Q4AH02 Cluster: Hydroxymethylglutaryl-CoA lyase; n=1;
Chlorobium phaeobacteroides BS1|Rep:
Hydroxymethylglutaryl-CoA lyase - Chlorobium
phaeobacteroides BS1
Length = 282
Score = 59.7 bits (138), Expect = 5e-08
Identities = 42/150 (28%), Positives = 76/150 (50%), Gaps = 3/150 (2%)
Frame = +2
Query: 146 IRIYEVGPRDGLQNESKFVPTDIKVELISKIVAAGIKNVESASFVSPKWVKQMSDSVDVM 325
I+I E PRDG Q + +PT KV+ I++++ G + VE SFVSP+ + QM+D+ DV+
Sbjct: 5 IKIIET-PRDGFQALNGIIPTSDKVKYINQLLRCGFQTVEVGSFVSPRLIPQMADTADVL 63
Query: 326 K--NIQRVPGVNYPVLVPNLKGYETAKQCNVEEIAIFP-AGSEGFSQKNLNCSVEEGLRR 496
+ ++Q V + VL KG + A + FP + S F ++N+ ++ + +
Sbjct: 64 RQLDLQDVTS-DIAVLAVTEKGGQMACDFKQVDQVFFPFSTSPTFLRRNIKSTLVQADQT 122
Query: 497 FKQVADEAVRDGLRVRGYISCVVGCPYDGP 586
+ + ++ + + S G Y P
Sbjct: 123 IDGLQNLCLKYNKELVVFFSMGFGSAYGDP 152
>UniRef50_Q583A8 Cluster: 3-hydroxy-3-methylglutaryl-CoA lyase,
putative; n=4; Trypanosoma|Rep:
3-hydroxy-3-methylglutaryl-CoA lyase, putative -
Trypanosoma brucei
Length = 431
Score = 59.3 bits (137), Expect = 7e-08
Identities = 37/129 (28%), Positives = 63/129 (48%), Gaps = 6/129 (4%)
Frame = +2
Query: 146 IRIYEVGPRDGLQNESKFVPTDIKVELISKIVAAGIKNVESASFVSPKWVKQMSDSVDVM 325
IR+ E PRD +Q F+PT+ K+ + ++ G ++ SFVSP+ V QM DS +V+
Sbjct: 11 IRMVEC-PRDAMQGLPHFIPTEQKIRYLKALLKCGFYALDCGSFVSPRAVPQMRDSTEVI 69
Query: 326 KNI-----QRVPGVNYPVLVPNLKGYETAKQCNVEEIAIFPAG-SEGFSQKNLNCSVEEG 487
N + V+V +L G++ A + + +P G E F Q+N S+
Sbjct: 70 ANCWKTMQEEKAAPKLSVVVASLAGFKQALETPGVSVIGYPIGCCERFQQRNAKKSIAMS 129
Query: 488 LRRFKQVAD 514
L + + +
Sbjct: 130 LDEIRNIKE 138
>UniRef50_Q46TI7 Cluster: Pyruvate carboxyltransferase; n=2;
Cupriavidus necator|Rep: Pyruvate carboxyltransferase -
Ralstonia eutropha (strain JMP134) (Alcaligenes
eutrophus)
Length = 321
Score = 57.2 bits (132), Expect = 3e-07
Identities = 43/158 (27%), Positives = 71/158 (44%), Gaps = 6/158 (3%)
Frame = +2
Query: 152 IYEVGPRDGLQNESKFVPTDIKVELISKIVAAGIKNVESASFVSPKWVKQMSDSVDVMKN 331
+ E G DGLQ+ + +P + IS AAG++++E + + + Q +D + + +
Sbjct: 12 VSEAGLCDGLQSLRQRLPAAARQAWISAEAAAGVRDIEVGTLAAFGVLPQTADLSEAVAH 71
Query: 332 IQRVPGVNYPVLVPNLKGYETAKQCNVEEIAIFPAGSEGFSQKNLNCSVEEGLRRFKQVA 511
VPG+ VPN G E A V IA+ E S +++N + + LR +++A
Sbjct: 72 ALAVPGLTVAARVPNFMGAERALAAGVHRIALPVFADEADSLRHMNRTHAQMLREVRRIA 131
Query: 512 D------EAVRDGLRVRGYISCVVGCPYDGPIHPKNIA 607
R L+VR + GC GP IA
Sbjct: 132 QRIGAVPRQARPRLQVR--LEMAFGCALTGPADEAAIA 167
>UniRef50_Q0S6Y1 Cluster: Hydroxymethylglutaryl-CoA lyase; n=5;
Actinomycetales|Rep: Hydroxymethylglutaryl-CoA lyase -
Rhodococcus sp. (strain RHA1)
Length = 312
Score = 54.0 bits (124), Expect = 3e-06
Identities = 36/149 (24%), Positives = 66/149 (44%)
Frame = +2
Query: 158 EVGPRDGLQNESKFVPTDIKVELISKIVAAGIKNVESASFVSPKWVKQMSDSVDVMKNIQ 337
+V RDGLQ K +PT K+E+ ++ G+ +E S P V M+++V+V+ +
Sbjct: 13 DVTLRDGLQLTGKMLPTARKLEIARRLFELGVPALEIGSMARPDLVPPMANTVEVISELT 72
Query: 338 RVPGVNYPVLVPNLKGYETAKQCNVEEIAIFPAGSEGFSQKNLNCSVEEGLRRFKQVADE 517
+ V V + E A + S+ +Q N+ S EE L +
Sbjct: 73 PDELDHCWVWVATPRHVEKAAAAGARHFQYCFSASDSHNQANIGRSTEESLAAMPSAIEL 132
Query: 518 AVRDGLRVRGYISCVVGCPYDGPIHPKNI 604
A + G ++ I+ CP++G + + +
Sbjct: 133 AQQVGGSIQLCIATSFTCPFEGRVPEQRV 161
>UniRef50_Q4MV51 Cluster: YngK protein; n=15; Bacillus|Rep: YngK
protein - Bacillus cereus G9241
Length = 638
Score = 37.1 bits (82), Expect = 0.33
Identities = 28/111 (25%), Positives = 51/111 (45%), Gaps = 4/111 (3%)
Frame = +2
Query: 221 ELISKIVA-AGIKNVESASFVSPKWVKQMSDSVDVMKNIQRVPGVNYPVLVPNLKGYETA 397
E+I+++ + + N+E + F S K +KQ D + + + + R YP LVPN+ + +
Sbjct: 311 EIINQLALNSTLSNIEGSIFFSYKDLKQ--DKLGIKERL-RANAYKYPALVPNMPWLDNS 367
Query: 398 KQCNVEEIAIFPAGSEGFSQKNLNCSVEEG---LRRFKQVADEAVRDGLRV 541
N EI++ + +N N E + RF + V D L +
Sbjct: 368 APSNPSEISVTDGPNGATISRNNNAGKEAAYFVVYRFNKEQQVNVNDSLAI 418
>UniRef50_Q6A1K1 Cluster: Putative chemosensory receptor 13; n=1;
Heliothis virescens|Rep: Putative chemosensory receptor
13 - Heliothis virescens (Noctuid moth) (Owlet moth)
Length = 425
Score = 36.7 bits (81), Expect = 0.43
Identities = 20/77 (25%), Positives = 38/77 (49%)
Frame = -1
Query: 553 NISPYSQAVTNGLVRDLFKSSKTFFHRAI*IFL*KSFRTSRKYSNFFYVALFSCFISFQI 374
N+ P+ + G+ RD+ ++ T+ H +F F + K+ + + F+ FIS+
Sbjct: 154 NMIPFYNCYSRGMFRDVIPANATYDHA---VFYSVPFDYTTKFKGYLAMTSFNVFISYTC 210
Query: 373 WNKYRVIHSRHSLNIFH 323
+ + V+ SL IFH
Sbjct: 211 TSYFCVVDLTISLVIFH 227
>UniRef50_Q54HL4 Cluster: Putative uncharacterized protein; n=2;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 347
Score = 35.1 bits (77), Expect = 1.3
Identities = 22/80 (27%), Positives = 43/80 (53%), Gaps = 7/80 (8%)
Frame = -1
Query: 400 FSCFISFQIWNKYRVIHSRHSLNIFHN----INTVTHLFNPFWTDKTC---RFYIFYTCS 242
F+ ++ Q + + V +R S + F++ ++ + +NP +T K + YIF T +
Sbjct: 258 FNAILACQYMSNFFVNETRKSNHKFNDEEVLFKSLIYNYNPTYTFKETHVEQIYIFNTST 317
Query: 241 NDFTNEFNFNVCWNKLRFIL 182
N+ N+FN N ++K FI+
Sbjct: 318 NNTKNDFNINQIFSKKLFII 337
>UniRef50_Q8UVR7 Cluster: Enteropeptidase; n=1; Takifugu
rubripes|Rep: Enteropeptidase - Fugu rubripes (Japanese
pufferfish) (Takifugu rubripes)
Length = 182
Score = 34.3 bits (75), Expect = 2.3
Identities = 15/39 (38%), Positives = 23/39 (58%)
Frame = +2
Query: 431 PAGSEGFSQKNLNCSVEEGLRRFKQVADEAVRDGLRVRG 547
P G G S+K L C+ E+G+ ++Q E D +R+RG
Sbjct: 43 PKGGGGVSRKKLTCTFEQGMCFWRQQPGEDDSDWIRIRG 81
>UniRef50_A5BTF3 Cluster: Putative uncharacterized protein; n=1;
Vitis vinifera|Rep: Putative uncharacterized protein -
Vitis vinifera (Grape)
Length = 681
Score = 33.9 bits (74), Expect = 3.0
Identities = 16/44 (36%), Positives = 24/44 (54%)
Frame = -1
Query: 325 HNINTVTHLFNPFWTDKTCRFYIFYTCSNDFTNEFNFNVCWNKL 194
+N++ HL N FW D T + + Y+C D + N NV WN +
Sbjct: 236 YNVDEDNHLANLFWADSTSK--LDYSCFGDAPLK-NLNVXWNDM 276
>UniRef50_Q2SRY1 Cluster: Peptidase C39 family protein; n=3;
Mycoplasma|Rep: Peptidase C39 family protein -
Mycoplasma capricolum subsp. capricolum (strain
California kid / ATCC27343 / NCTC 10154)
Length = 629
Score = 33.5 bits (73), Expect = 4.0
Identities = 26/99 (26%), Positives = 41/99 (41%)
Frame = -1
Query: 442 RTSRKYSNFFYVALFSCFISFQIWNKYRVIHSRHSLNIFHNINTVTHLFNPFWTDKTCRF 263
+T K FY L I + N Y I S + +NT++ L N F
Sbjct: 236 KTKTKKLEIFYYYLVENNIKLDVINSYSEIEFISSFQTYVLLNTISGLINSL----VILF 291
Query: 262 YIFYTCSNDFTNEFNFNVCWNKLRFILKAISRSYFINSD 146
IFY F F+F++ W +L ++ ++FIN +
Sbjct: 292 VIFYINKIIFLVLFSFDIFW-----LLISLVHNFFINKN 325
>UniRef50_A6GLW0 Cluster: Rhs family protein; n=1; Limnobacter sp.
MED105|Rep: Rhs family protein - Limnobacter sp. MED105
Length = 1598
Score = 33.5 bits (73), Expect = 4.0
Identities = 15/46 (32%), Positives = 23/46 (50%)
Frame = -1
Query: 229 NEFNFNVCWNKLRFILKAISRSYFINSDFRGYCTKTTLQEVIRTEY 92
N + F+ W +L + + RS + D G CT+ T E + TEY
Sbjct: 840 NTYQFDA-WGRLASVTNPLGRSAYYAYDLMGRCTRATNHEGLSTEY 884
>UniRef50_Q86K87 Cluster: Similar to Dictyostelium discoideum (Slime
mold). DG2033 protein; n=2; Dictyostelium
discoideum|Rep: Similar to Dictyostelium discoideum
(Slime mold). DG2033 protein - Dictyostelium discoideum
(Slime mold)
Length = 682
Score = 33.5 bits (73), Expect = 4.0
Identities = 19/65 (29%), Positives = 32/65 (49%), Gaps = 5/65 (7%)
Frame = -1
Query: 430 KYSNFFYVALFSCFIS-----FQIWNKYRVIHSRHSLNIFHNINTVTHLFNPFWTDKTCR 266
+Y+ FFY+ + SC F+I++ ++S NI I + L+N FW
Sbjct: 208 EYNLFFYLFVLSCIGLVCSGLFRIYSNQEFVYSFPKANIPTFIQIKSMLYNNFWISFYTS 267
Query: 265 FYIFY 251
FY+F+
Sbjct: 268 FYLFF 272
>UniRef50_Q22FZ2 Cluster: Hormone sensitive lipase; n=1; Tetrahymena
thermophila SB210|Rep: Hormone sensitive lipase -
Tetrahymena thermophila SB210
Length = 951
Score = 33.5 bits (73), Expect = 4.0
Identities = 19/74 (25%), Positives = 33/74 (44%), Gaps = 2/74 (2%)
Frame = +2
Query: 164 GPRDGLQNESKFVPTDIKVELISKIVAAGI--KNVESASFVSPKWVKQMSDSVDVMKNIQ 337
G +G QN+ + K+ +I I G N S + KW Q+ DSV + + +
Sbjct: 582 GGANGNQNDEGNIEPKKKINIILHIHGGGFVAMNTFSHQIYTRKWANQVDDSVVISIDYR 641
Query: 338 RVPGVNYPVLVPNL 379
+ P YP + ++
Sbjct: 642 KAPEHRYPAAIDDV 655
>UniRef50_A1ZDW2 Cluster: Transcriptional regulator, putative; n=1;
Microscilla marina ATCC 23134|Rep: Transcriptional
regulator, putative - Microscilla marina ATCC 23134
Length = 383
Score = 33.1 bits (72), Expect = 5.3
Identities = 30/87 (34%), Positives = 41/87 (47%), Gaps = 9/87 (10%)
Frame = -1
Query: 337 LNIFHNINTVTHLFNPFWTDKTCRFYIFYTCSND---FTNEFNFNVCWNKLRFILKAIS- 170
L I +INTV+ LFN + RF I YT + F + N + W + FIL A S
Sbjct: 151 LGIKAHINTVSILFNGVYYYLIIRFIIQYTKQHQLSFFKSLPNKRLRWVRTFFILSAFSY 210
Query: 169 -----RSYFINSDFRGYCTKTTLQEVI 104
R++F+ D + Y T L VI
Sbjct: 211 IHWVYRTFFVLRDLQDY-TSAALSAVI 236
>UniRef50_Q57926 Cluster: 2-isopropylmalate synthase 1; n=10;
Euryarchaeota|Rep: 2-isopropylmalate synthase 1 -
Methanococcus jannaschii
Length = 398
Score = 33.1 bits (72), Expect = 5.3
Identities = 39/137 (28%), Positives = 61/137 (44%), Gaps = 4/137 (2%)
Frame = +2
Query: 143 EIRIYEVGPRDGLQNESKFVPTDIKVELISKIVAAGIKNVESASFVSPKWVKQMSDSVDV 322
+I IY+ RDG Q + K+E+ K+ G+K +E A F P ++ +D V
Sbjct: 23 DIYIYDTTLRDGEQTPGVCFTKEQKLEIARKLDELGLKQIE-AGF--PIVSEREADIVKT 79
Query: 323 MKNIQRVPGVNYPVLV---PNLKGYETAKQCNVEEIAIFPAGSE-GFSQKNLNCSVEEGL 490
+ N G+N +L K + A +C+V+ I F A S K N S++E L
Sbjct: 80 IAN----EGLNADILALCRALKKDIDKAIECDVDGIITFIATSPLHLKYKFNNKSLDEIL 135
Query: 491 RRFKQVADEAVRDGLRV 541
+ + A GL V
Sbjct: 136 EMGVEAVEYAKEHGLFV 152
>UniRef50_A7M2Z0 Cluster: Putative uncharacterized protein; n=3;
Bacteroides|Rep: Putative uncharacterized protein -
Bacteroides ovatus ATCC 8483
Length = 562
Score = 32.7 bits (71), Expect = 7.0
Identities = 36/150 (24%), Positives = 68/150 (45%), Gaps = 3/150 (2%)
Frame = +2
Query: 23 IVIIALRNTQLIMNNVTKTCVLNILRSNNFLQRSLSTVAPEIRIYEVGPRDGLQNESKFV 202
I +I TQ +N+V KT +++ +F+ + + + E + P DG++ E+ V
Sbjct: 162 IPLITRTYTQEEINSVRKTSFADVI---DFIAKECTEITREGGL----PEDGVRGETGRV 214
Query: 203 PTDIKVELISKIVAAGIKNVESASFVSPKWVKQMSDSVDVMK-NIQRVPGVNYPVLVPNL 379
+ L S+ + ++ + + KW + +V+K N ++P V+ L +L
Sbjct: 215 TKGAALALKSRALLYAASDLHNPAHDLTKWEAAAKAAYEVIKMNKYQLPNVSTDPLYSDL 274
Query: 380 KGYET--AKQCNVEEIAIFPAGSEGFSQKN 463
G E +KQ E AI A + F +N
Sbjct: 275 GGNEVLKSKQLIFERRAI--ATTSDFESRN 302
>UniRef50_A5Z9A6 Cluster: Putative uncharacterized protein; n=1;
Eubacterium ventriosum ATCC 27560|Rep: Putative
uncharacterized protein - Eubacterium ventriosum ATCC
27560
Length = 627
Score = 32.7 bits (71), Expect = 7.0
Identities = 21/69 (30%), Positives = 32/69 (46%)
Frame = +2
Query: 257 NVESASFVSPKWVKQMSDSVDVMKNIQRVPGVNYPVLVPNLKGYETAKQCNVEEIAIFPA 436
N A +S K ++S+S DV KNI+ Y + N+K ++ N +I +
Sbjct: 220 NEYKAKVMSEKEFNKISNSKDVKKNIEEALKKEYSDGIKNVKYTYLTREDNTLDINMVVT 279
Query: 437 GSEGFSQKN 463
SEG KN
Sbjct: 280 DSEGTKYKN 288
>UniRef50_A4INR3 Cluster: Na+/H+ antiporter NapA-like protein; n=1;
Geobacillus thermodenitrificans NG80-2|Rep: Na+/H+
antiporter NapA-like protein - Geobacillus
thermodenitrificans (strain NG80-2)
Length = 341
Score = 32.7 bits (71), Expect = 7.0
Identities = 25/95 (26%), Positives = 45/95 (47%), Gaps = 1/95 (1%)
Frame = -1
Query: 409 VALFSCFISFQIWNKYRVIHSRHSLNIFHNINTVTHLFNPFWTDKTCRFYIFYTCSNDFT 230
VA+ +I+ K I + +F VT F + ++ RF +Y+ +T
Sbjct: 242 VAISVTNFKHEIFEKVETISYSIFVPVFFTSIGVTAQFRYYSKFRSNRFIKYYS----YT 297
Query: 229 NEFNFNVCWNKLRFI-LKAISRSYFINSDFRGYCT 128
N+ N+ + W K+ +I L+ + R++F N RG T
Sbjct: 298 NKINWCIYWGKIGWIQLEQLIRNWFSNGVQRGSST 332
>UniRef50_Q8TMI0 Cluster: Transposase; n=7; Methanosarcina|Rep:
Transposase - Methanosarcina acetivorans
Length = 381
Score = 32.7 bits (71), Expect = 7.0
Identities = 28/93 (30%), Positives = 44/93 (47%), Gaps = 2/93 (2%)
Frame = +2
Query: 230 SKIVAAGIKNVESASFVS--PKWVKQMSDSVDVMKNIQRVPGVNYPVLVPNLKGYETAKQ 403
S+ VA+GIK S V+ PK V S+ +K ++ P + +L+ +L Y+T
Sbjct: 89 SRTVASGIKVGVMVSAVANGPKTVALYSEKTAEIKTLKIGPWIKDRILLVDLGFYKTQMF 148
Query: 404 CNVEEIAIFPAGSEGFSQKNLNCSVEEGLRRFK 502
VEE + + + SVEEGL + K
Sbjct: 149 ARVEENGGYFVSRIRKNMDPILVSVEEGLSKTK 181
>UniRef50_UPI00004986B4 Cluster: phospholipid-transporting P-type
ATPase; n=1; Entamoeba histolytica HM-1:IMSS|Rep:
phospholipid-transporting P-type ATPase - Entamoeba
histolytica HM-1:IMSS
Length = 982
Score = 32.3 bits (70), Expect = 9.3
Identities = 27/121 (22%), Positives = 53/121 (43%), Gaps = 13/121 (10%)
Frame = -1
Query: 427 YSNFFYVALFSCFI------SFQIWNKYRVIHSRHS----LNIFHNINTVTHLF---NPF 287
Y+N ++L+ C +F I N + HS ++ N+ + TV +F
Sbjct: 319 YNNLVPISLYVCLEIIKLIQAFFIENDEDIKHSVNARCRNTNLVEELGTVKFIFADKTGT 378
Query: 286 WTDKTCRFYIFYTCSNDFTNEFNFNVCWNKLRFILKAISRSYFINSDFRGYCTKTTLQEV 107
T RF + N+FT F+F+ K ++ L+ +S + + +GY + +E+
Sbjct: 379 LTKNEMRFKKCFIDGNEFTTSFSFDNANQKEQWFLRCLSTCHTADKTDKGYSASSADEEI 438
Query: 106 I 104
+
Sbjct: 439 L 439
>UniRef50_Q5WLW4 Cluster: Putative uncharacterized protein; n=1;
Bacillus clausii KSM-K16|Rep: Putative uncharacterized
protein - Bacillus clausii (strain KSM-K16)
Length = 468
Score = 32.3 bits (70), Expect = 9.3
Identities = 23/89 (25%), Positives = 43/89 (48%)
Frame = +2
Query: 155 YEVGPRDGLQNESKFVPTDIKVELISKIVAAGIKNVESASFVSPKWVKQMSDSVDVMKNI 334
YEV DG++ + + V T+ E ++++A G K E+ +V S++ + +
Sbjct: 288 YEVTLEDGVEVDRQLVKTETVEESENRVIAVGTKQEEAKEYV--------SETQTAHETV 339
Query: 335 QRVPGVNYPVLVPNLKGYETAKQCNVEEI 421
+ P V+ PV P E+AK +E+
Sbjct: 340 SQEP-VDQPVSEPEKPKQESAKPQEKQEV 367
>UniRef50_Q081X8 Cluster: Phosphoadenosine phosphosulfate reductase;
n=2; Alteromonadales|Rep: Phosphoadenosine
phosphosulfate reductase - Shewanella frigidimarina
(strain NCIMB 400)
Length = 298
Score = 32.3 bits (70), Expect = 9.3
Identities = 12/34 (35%), Positives = 23/34 (67%)
Frame = +2
Query: 452 SQKNLNCSVEEGLRRFKQVADEAVRDGLRVRGYI 553
SQ++ C+V+ L+ F+Q D +RDG +++ Y+
Sbjct: 93 SQRDRWCTVQMKLKPFEQWLDSFIRDGYKIKNYV 126
>UniRef50_A2ECX7 Cluster: Major facilitator superfamily protein;
n=1; Trichomonas vaginalis G3|Rep: Major facilitator
superfamily protein - Trichomonas vaginalis G3
Length = 408
Score = 32.3 bits (70), Expect = 9.3
Identities = 13/29 (44%), Positives = 18/29 (62%)
Frame = -1
Query: 349 SRHSLNIFHNINTVTHLFNPFWTDKTCRF 263
S SLN+F NI T+ +F+PF CR+
Sbjct: 41 SEKSLNLFSNITTIVGIFSPFLPVLLCRY 69
>UniRef50_Q9ZRT1 Cluster: Protein gamma response 1; n=3; Arabidopsis
thaliana|Rep: Protein gamma response 1 - Arabidopsis
thaliana (Mouse-ear cress)
Length = 589
Score = 32.3 bits (70), Expect = 9.3
Identities = 21/59 (35%), Positives = 28/59 (47%)
Frame = +2
Query: 326 KNIQRVPGVNYPVLVPNLKGYETAKQCNVEEIAIFPAGSEGFSQKNLNCSVEEGLRRFK 502
K+ + V V NLKG E KQC A+ P +EG K+L C EG+ R +
Sbjct: 512 KSFKHVESVRKKAERENLKGIE-CKQCKKFYDAVHPE-NEGNGNKSLRCEHHEGVSRHR 568
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 558,863,884
Number of Sequences: 1657284
Number of extensions: 10898580
Number of successful extensions: 33526
Number of sequences better than 10.0: 93
Number of HSP's better than 10.0 without gapping: 32424
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 33472
length of database: 575,637,011
effective HSP length: 97
effective length of database: 414,880,463
effective search space used: 43562448615
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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