Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= bmmt5a10
(713 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X07994-1|CAA30801.1| 1927|Homo sapiens protein ( Human mRNA for ... 237 4e-62
AY191611-1|AAP12677.1| 1003|Homo sapiens lactase-phlorizin hydro... 237 4e-62
M61850-1|AAA59504.1| 1927|Homo sapiens lactase phlorizinhydrolas... 236 7e-62
AC011893-3|AAX88924.1| 1927|Homo sapiens unknown protein. 236 7e-62
AY358729-1|AAQ89091.1| 567|Homo sapiens KPVW3022 protein. 215 1e-55
AL161898-1|CAH71888.1| 1012|Homo sapiens klotho protein. 210 3e-54
AB009667-2|BAA24941.1| 549|Homo sapiens Klotho protein (KL) pro... 210 3e-54
AB009667-1|BAA24940.1| 1012|Homo sapiens Klotho protein (KL) pro... 210 3e-54
AB005142-1|BAA23382.1| 1012|Homo sapiens klotho protein. 210 3e-54
BC101829-1|AAI01830.1| 469|Homo sapiens cytosolic beta-glucosid... 204 2e-52
AK222963-1|BAD96683.1| 469|Homo sapiens cytosolic beta-glucosid... 204 2e-52
AJ278964-1|CAC08178.1| 469|Homo sapiens cytosolic beta-glucosid... 204 2e-52
AF323990-1|AAL37305.1| 469|Homo sapiens cytosolic beta-glucosid... 204 2e-52
AB017913-1|BAB18741.1| 469|Homo sapiens cytosolic beta-glucosid... 204 2e-52
AF317840-1|AAG39217.1| 469|Homo sapiens cytosolic beta-glucosid... 204 3e-52
Z92540-2|CAC94767.1| 273|Homo sapiens 179I15.1 (klotho) protein. 189 1e-47
BC113653-1|AAI13654.1| 1044|Homo sapiens klotho beta protein. 177 2e-44
BC104871-1|AAI04872.1| 1044|Homo sapiens klotho beta protein. 177 2e-44
AB079373-1|BAC56857.1| 1044|Homo sapiens klotho beta like protei... 177 2e-44
BC109377-1|AAI09378.1| 162|Homo sapiens GBA3 protein protein. 99 8e-21
BC029362-1|AAH29362.1| 162|Homo sapiens GBA3 protein protein. 99 8e-21
BC070188-1|AAH70188.1| 162|Homo sapiens GBA3 protein protein. 99 1e-20
Z84483-1|CAC94773.1| 739|Homo sapiens 46H23.1 (Klotho) protein. 93 9e-19
BT007435-1|AAP36103.1| 441|Homo sapiens G protein-coupled recep... 32 2.3
BC125081-1|AAI25082.1| 486|Homo sapiens G protein-coupled recep... 32 2.3
BC125080-1|AAI25081.1| 486|Homo sapiens G protein-coupled recep... 32 2.3
BC110848-1|AAI10849.1| 486|Homo sapiens G protein-coupled recep... 32 2.3
BC016860-1|AAH16860.2| 448|Homo sapiens GPRC5C protein protein. 32 2.3
AK075397-1|BAC11595.1| 441|Homo sapiens protein ( Homo sapiens ... 32 2.3
AJ276102-1|CAC00633.1| 441|Homo sapiens GPRC5C protein. 32 2.3
AF207989-1|AAF72870.1| 441|Homo sapiens orphan G-protein couple... 32 2.3
BC034469-1|AAH34469.1| 849|Homo sapiens coiled-coil domain cont... 30 7.2
AK001648-1|BAA91808.1| 849|Homo sapiens protein ( Homo sapiens ... 30 7.2
>X07994-1|CAA30801.1| 1927|Homo sapiens protein ( Human mRNA for
lactase-phlorizin hydrolase LPH (EC 3.2.1.23-62). ).
Length = 1927
Score = 237 bits (579), Expect = 4e-62
Identities = 106/210 (50%), Positives = 140/210 (66%)
Frame = +3
Query: 84 FPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVERD 263
F DDFL G ++++YQIEGAW+ DGKG +IWD TH + VKD +TGDIA +SYH ++ D
Sbjct: 903 FRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYHQLDAD 962
Query: 264 VEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHWD 443
+ M+R L + YRFS+SWSRI P+G + IN GVDYYNRLIN ++ I PM+TLFHWD
Sbjct: 963 LNMLRALKVKAYRFSISWSRIFPTGRNSSINSHGVDYYNRLINGLVASNIFPMVTLFHWD 1022
Query: 444 LPQKLQELGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGYGSVHKAPI 623
LPQ LQ++GG+ NP F+ YA + FGDRVK W+T NEP + + GYGS P
Sbjct: 1023 LPQALQDIGGWENPALIDLFDSYADFCFQTFGDRVKFWMTFNEPMYLAWLGYGSGEFPPG 1082
Query: 624 LXATAIGTYLCAKNVLIAHAKAYHLYNNEF 713
+ Y A V+ AHA+ YH Y+ ++
Sbjct: 1083 VKDPGWAPYRIAHTVIKAHARVYHTYDEKY 1112
Score = 223 bits (545), Expect = 5e-58
Identities = 100/212 (47%), Positives = 142/212 (66%), Gaps = 1/212 (0%)
Frame = +3
Query: 81 RFPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVER 260
RFP+ F+ A+A+YQIEGAW DGKG +IWD +H P V++ + GD+A +SYH +
Sbjct: 1376 RFPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSHT-PLRVENDAIGDVACDSYHKIAE 1434
Query: 261 DVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHW 440
D+ ++ LG+ YRFS+SWSRILP G INEAG++YY RLI+ +L I P +T++HW
Sbjct: 1435 DLVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLAASIQPQVTIYHW 1494
Query: 441 DLPQKLQELGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGYGSVHKAP 620
DLPQ LQ++GG+ N F++YA V++ GD+VK WIT+NEP I Y+GYG AP
Sbjct: 1495 DLPQTLQDVGGWENETIVQRFKEYADVLFQRLGDKVKFWITLNEPFVIAYQGYGYGTAAP 1554
Query: 621 -ILXATAIGTYLCAKNVLIAHAKAYHLYNNEF 713
+ Y+ N++ AHA+A+HLYN+ +
Sbjct: 1555 GVSNRPGTAPYIVGHNLIKAHAEAWHLYNDVY 1586
Score = 188 bits (458), Expect = 2e-47
Identities = 91/212 (42%), Positives = 128/212 (60%), Gaps = 1/212 (0%)
Frame = +3
Query: 75 QRRFPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDG-STGDIAANSYHN 251
Q FP+ FL G +T ++ +EG W E G+G +IWD P +G +T ++A++SYH
Sbjct: 379 QDTFPEGFLWGASTGAFNVEGGWAEGGRGVSIWD---PRRPLNTTEGQATLEVASDSYHK 435
Query: 252 VERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITL 431
V DV ++ L VY+FS+SWSRI P G + + GV YYN+LI+ + GI PM TL
Sbjct: 436 VASDVALLCGLRAQVYKFSISWSRIFPMGHGSSPSLPGVAYYNKLIDRLQDAGIEPMATL 495
Query: 432 FHWDLPQKLQELGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGYGSVH 611
FHWDLPQ LQ+ GG+ N F DYA ++ FGDRVK W+T +EP + Y GYG+
Sbjct: 496 FHWDLPQALQDHGGWQNESVVDAFLDYAAFCFSTFGDRVKLWVTFHEPWVMSYAGYGTGQ 555
Query: 612 KAPILXATAIGTYLCAKNVLIAHAKAYHLYNN 707
P + + ++ A VL AHA+ +H YN+
Sbjct: 556 HPPGISDPGVASFKVAHLVLKAHARTWHHYNS 587
Score = 58.8 bits (136), Expect = 2e-08
Identities = 33/100 (33%), Positives = 50/100 (50%), Gaps = 1/100 (1%)
Frame = +3
Query: 297 YRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHWDLP-QKLQELGG 473
Y+ LSW+++LP+G +E V Y RL+ + + PM+ L H LP L+
Sbjct: 87 YKVFLSWAQLLPAGSTQNPDEKTVQCYRRLLKALKTARLQPMVILHHQTLPASTLRRTEA 146
Query: 474 FANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYE 593
FA+ F DYA + +FGD V W T ++ E+ E
Sbjct: 147 FAD-----LFADYATFAFHSFGDLVGIWFTFSDLEEVIKE 181
>AY191611-1|AAP12677.1| 1003|Homo sapiens lactase-phlorizin
hydrolase-1 protein.
Length = 1003
Score = 237 bits (579), Expect = 4e-62
Identities = 106/210 (50%), Positives = 140/210 (66%)
Frame = +3
Query: 84 FPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVERD 263
F DDFL G ++++YQIEGAW+ DGKG +IWD TH + VKD +TGDIA +SYH ++ D
Sbjct: 335 FRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYHQLDAD 394
Query: 264 VEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHWD 443
+ M+R L + YRFS+SWSRI P+G + IN GVDYYNRLIN ++ I PM+TLFHWD
Sbjct: 395 LNMLRALKVKAYRFSISWSRIFPTGRNSSINSHGVDYYNRLINGLVASNIFPMVTLFHWD 454
Query: 444 LPQKLQELGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGYGSVHKAPI 623
LPQ LQ++GG+ NP F+ YA + FGDRVK W+T NEP + + GYGS P
Sbjct: 455 LPQALQDIGGWENPALIDLFDSYADFCFQTFGDRVKFWMTFNEPMYLAWLGYGSGEFPPG 514
Query: 624 LXATAIGTYLCAKNVLIAHAKAYHLYNNEF 713
+ Y A V+ AHA+ YH Y+ ++
Sbjct: 515 VKDPGWAPYRIAHTVIKAHARVYHTYDEKY 544
Score = 205 bits (500), Expect = 1e-52
Identities = 90/181 (49%), Positives = 125/181 (69%)
Frame = +3
Query: 81 RFPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVER 260
RFP+ F+ A+A+YQIEGAW DGKG +IWD +H P V++ + GD+A +SYH +
Sbjct: 808 RFPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSHT-PLRVENDAIGDVACDSYHKIAE 866
Query: 261 DVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHW 440
D+ ++ LG+ YRFS+SWSRILP G INEAG++YY RLI+ +L I P +T++HW
Sbjct: 867 DLVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLAASIQPQVTIYHW 926
Query: 441 DLPQKLQELGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGYGSVHKAP 620
DLPQ LQ++GG+ N F++YA V++ GD+VK WIT+NEP I Y+GYG AP
Sbjct: 927 DLPQTLQDVGGWENETIVQRFKEYADVLFQRLGDKVKFWITLNEPFVIAYQGYGYGTAAP 986
Query: 621 I 623
+
Sbjct: 987 V 987
>M61850-1|AAA59504.1| 1927|Homo sapiens lactase phlorizinhydrolase
protein.
Length = 1927
Score = 236 bits (577), Expect = 7e-62
Identities = 106/210 (50%), Positives = 140/210 (66%)
Frame = +3
Query: 84 FPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVERD 263
F DDFL G ++++YQIEGAW+ DGKG +IWD TH + VKD +TGDIA +SYH ++ D
Sbjct: 903 FRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYHQLDAD 962
Query: 264 VEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHWD 443
+ M+R L + YRFS+SWSRI P+G + IN GVDYYNRLIN ++ I PM+TLFHWD
Sbjct: 963 LNMLRALKVKAYRFSISWSRIFPTGRNSSINSHGVDYYNRLINGLVASNIFPMVTLFHWD 1022
Query: 444 LPQKLQELGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGYGSVHKAPI 623
LPQ LQ++GG+ NP F+ YA + FGDRVK W+T NEP + + GYGS P
Sbjct: 1023 LPQALQDIGGWENPALIDLFDSYADFCFQTFGDRVKFWMTFNEPMYLAWLGYGSGEFPPG 1082
Query: 624 LXATAIGTYLCAKNVLIAHAKAYHLYNNEF 713
+ Y A V+ AHA+ YH Y+ ++
Sbjct: 1083 VKDPGWAPYRIAHAVIKAHARVYHTYDEKY 1112
Score = 223 bits (545), Expect = 5e-58
Identities = 100/212 (47%), Positives = 142/212 (66%), Gaps = 1/212 (0%)
Frame = +3
Query: 81 RFPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVER 260
RFP+ F+ A+A+YQIEGAW DGKG +IWD +H P V++ + GD+A +SYH +
Sbjct: 1376 RFPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSHT-PLRVENDAIGDVACDSYHKIAE 1434
Query: 261 DVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHW 440
D+ ++ LG+ YRFS+SWSRILP G INEAG++YY RLI+ +L I P +T++HW
Sbjct: 1435 DLVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLAASIQPQVTIYHW 1494
Query: 441 DLPQKLQELGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGYGSVHKAP 620
DLPQ LQ++GG+ N F++YA V++ GD+VK WIT+NEP I Y+GYG AP
Sbjct: 1495 DLPQTLQDVGGWENETIVQRFKEYADVLFQRLGDKVKFWITLNEPFVIAYQGYGYGTAAP 1554
Query: 621 -ILXATAIGTYLCAKNVLIAHAKAYHLYNNEF 713
+ Y+ N++ AHA+A+HLYN+ +
Sbjct: 1555 GVSNRPGTAPYIVGHNLIKAHAEAWHLYNDVY 1586
Score = 188 bits (458), Expect = 2e-47
Identities = 91/212 (42%), Positives = 128/212 (60%), Gaps = 1/212 (0%)
Frame = +3
Query: 75 QRRFPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDG-STGDIAANSYHN 251
Q FP+ FL G +T ++ +EG W E G+G +IWD P +G +T ++A++SYH
Sbjct: 379 QDTFPEGFLWGASTGAFNVEGGWAEGGRGVSIWD---PRRPLNTTEGQATLEVASDSYHK 435
Query: 252 VERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITL 431
V DV ++ L VY+FS+SWSRI P G + + GV YYN+LI+ + GI PM TL
Sbjct: 436 VASDVALLCGLRAQVYKFSISWSRIFPMGHGSSPSLPGVAYYNKLIDRLQDAGIEPMATL 495
Query: 432 FHWDLPQKLQELGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGYGSVH 611
FHWDLPQ LQ+ GG+ N F DYA ++ FGDRVK W+T +EP + Y GYG+
Sbjct: 496 FHWDLPQALQDHGGWQNESVVDAFLDYAAFCFSTFGDRVKLWVTFHEPWVMSYAGYGTGQ 555
Query: 612 KAPILXATAIGTYLCAKNVLIAHAKAYHLYNN 707
P + + ++ A VL AHA+ +H YN+
Sbjct: 556 HPPGISDPGVASFKVAHLVLKAHARTWHHYNS 587
Score = 58.8 bits (136), Expect = 2e-08
Identities = 33/100 (33%), Positives = 50/100 (50%), Gaps = 1/100 (1%)
Frame = +3
Query: 297 YRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHWDLP-QKLQELGG 473
Y+ LSW+++LP+G +E V Y RL+ + + PM+ L H LP L+
Sbjct: 87 YKVFLSWAQLLPAGSTQNPDEKTVQCYRRLLKALKTARLQPMVILHHQTLPASTLRRTEA 146
Query: 474 FANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYE 593
FA+ F DYA + +FGD V W T ++ E+ E
Sbjct: 147 FAD-----LFADYATFAFHSFGDLVGIWFTFSDLEEVIKE 181
>AC011893-3|AAX88924.1| 1927|Homo sapiens unknown protein.
Length = 1927
Score = 236 bits (577), Expect = 7e-62
Identities = 106/210 (50%), Positives = 140/210 (66%)
Frame = +3
Query: 84 FPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVERD 263
F DDFL G ++++YQIEGAW+ DGKG +IWD TH + VKD +TGDIA +SYH ++ D
Sbjct: 903 FRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYHQLDAD 962
Query: 264 VEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHWD 443
+ M+R L + YRFS+SWSRI P+G + IN GVDYYNRLIN ++ I PM+TLFHWD
Sbjct: 963 LNMLRALKVKAYRFSISWSRIFPTGRNSSINSHGVDYYNRLINGLVASNIFPMVTLFHWD 1022
Query: 444 LPQKLQELGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGYGSVHKAPI 623
LPQ LQ++GG+ NP F+ YA + FGDRVK W+T NEP + + GYGS P
Sbjct: 1023 LPQALQDIGGWENPALIDLFDSYADFCFQTFGDRVKFWMTFNEPMYLAWLGYGSGEFPPG 1082
Query: 624 LXATAIGTYLCAKNVLIAHAKAYHLYNNEF 713
+ Y A V+ AHA+ YH Y+ ++
Sbjct: 1083 VKDPGWAPYRIAHAVIKAHARVYHTYDEKY 1112
Score = 223 bits (545), Expect = 5e-58
Identities = 100/212 (47%), Positives = 142/212 (66%), Gaps = 1/212 (0%)
Frame = +3
Query: 81 RFPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVER 260
RFP+ F+ A+A+YQIEGAW DGKG +IWD +H P V++ + GD+A +SYH +
Sbjct: 1376 RFPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSHT-PLRVENDAIGDVACDSYHKIAE 1434
Query: 261 DVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHW 440
D+ ++ LG+ YRFS+SWSRILP G INEAG++YY RLI+ +L I P +T++HW
Sbjct: 1435 DLVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLAASIQPQVTIYHW 1494
Query: 441 DLPQKLQELGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGYGSVHKAP 620
DLPQ LQ++GG+ N F++YA V++ GD+VK WIT+NEP I Y+GYG AP
Sbjct: 1495 DLPQTLQDVGGWENETIVQRFKEYADVLFQRLGDKVKFWITLNEPFVIAYQGYGYGTAAP 1554
Query: 621 -ILXATAIGTYLCAKNVLIAHAKAYHLYNNEF 713
+ Y+ N++ AHA+A+HLYN+ +
Sbjct: 1555 GVSNRPGTAPYIVGHNLIKAHAEAWHLYNDVY 1586
Score = 188 bits (458), Expect = 2e-47
Identities = 91/212 (42%), Positives = 128/212 (60%), Gaps = 1/212 (0%)
Frame = +3
Query: 75 QRRFPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDG-STGDIAANSYHN 251
Q FP+ FL G +T ++ +EG W E G+G +IWD P +G +T ++A++SYH
Sbjct: 379 QDTFPEGFLWGASTGAFNVEGGWAEGGRGVSIWD---PRRPLNTTEGQATLEVASDSYHK 435
Query: 252 VERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITL 431
V DV ++ L VY+FS+SWSRI P G + + GV YYN+LI+ + GI PM TL
Sbjct: 436 VASDVALLCGLRAQVYKFSISWSRIFPMGHGSSPSLPGVAYYNKLIDRLQDAGIEPMATL 495
Query: 432 FHWDLPQKLQELGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGYGSVH 611
FHWDLPQ LQ+ GG+ N F DYA ++ FGDRVK W+T +EP + Y GYG+
Sbjct: 496 FHWDLPQALQDHGGWQNESVVDAFLDYAAFCFSTFGDRVKLWVTFHEPWVMSYAGYGTGQ 555
Query: 612 KAPILXATAIGTYLCAKNVLIAHAKAYHLYNN 707
P + + ++ A VL AHA+ +H YN+
Sbjct: 556 HPPGISDPGVASFKVAHLVLKAHARTWHHYNS 587
Score = 58.8 bits (136), Expect = 2e-08
Identities = 33/100 (33%), Positives = 50/100 (50%), Gaps = 1/100 (1%)
Frame = +3
Query: 297 YRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHWDLP-QKLQELGG 473
Y+ LSW+++LP+G +E V Y RL+ + + PM+ L H LP L+
Sbjct: 87 YKVFLSWAQLLPAGSTQNPDEKTVQCYRRLLKALKTARLQPMVILHHQTLPASTLRRTEA 146
Query: 474 FANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYE 593
FA+ F DYA + +FGD V W T ++ E+ E
Sbjct: 147 FAD-----LFADYATFAFHSFGDLVGIWFTFSDLEEVIKE 181
>AY358729-1|AAQ89091.1| 567|Homo sapiens KPVW3022 protein.
Length = 567
Score = 215 bits (526), Expect = 1e-55
Identities = 95/209 (45%), Positives = 139/209 (66%), Gaps = 2/209 (0%)
Frame = +3
Query: 84 FPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVERD 263
FP F G +++YQ EGAW++DGKG +IWD TH+ V T D+A + Y+ V+ D
Sbjct: 37 FPLGFSWGVGSSAYQTEGAWDQDGKGPSIWDVFTHSGKGKVLGNETADVACDGYYKVQED 96
Query: 264 VEMMRELGLDVYRFSLSWSRILPSGF-ANEINEAGVDYYNRLINEMLKYGITPMITLFHW 440
+ ++REL ++ YRFSLSW R+LP+G A ++N+ G+++Y+ LI+ +L ITP++TL HW
Sbjct: 97 IILLRELHVNHYRFSLSWPRLLPTGIRAEQVNKKGIEFYSDLIDALLSSNITPIVTLHHW 156
Query: 441 DLPQKLQ-ELGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGYGSVHKA 617
DLPQ LQ + GG+ N + +F DYA + + FGDRVKHWIT ++PR + +GY + H A
Sbjct: 157 DLPQLLQVKYGGWQNVSMANYFRDYANLCFEAFGDRVKHWITFSDPRAMAEKGYETGHHA 216
Query: 618 PILXATAIGTYLCAKNVLIAHAKAYHLYN 704
P L G Y A +++ AHAK +H YN
Sbjct: 217 PGLKLRGTGLYKAAHHIIKAHAKTWHSYN 245
>AL161898-1|CAH71888.1| 1012|Homo sapiens klotho protein.
Length = 1012
Score = 210 bits (514), Expect = 3e-54
Identities = 101/229 (44%), Positives = 143/229 (62%), Gaps = 16/229 (6%)
Frame = +3
Query: 75 QRRFPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDG------------- 215
Q FPD FL +A+YQ EG W + GKG +IWD TH+ A D
Sbjct: 58 QGTFPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPL 117
Query: 216 --STGDIAANSYHNVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLI 389
+TGD+A++SY+NV RD E +RELG+ YRFS+SW+R+LP+G A N G+ YY RL+
Sbjct: 118 QPATGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLL 177
Query: 390 NEMLKYGITPMITLFHWDLPQKLQE-LGGFANPLASIWFEDYARVVYTNFGDRVKHWITI 566
+ + G+ P++TL+HWDLPQ+LQ+ GG+AN + F DYA + + +FG +VK+WITI
Sbjct: 178 ERLRELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITI 237
Query: 567 NEPREICYEGYGSVHKAPILXATAIGTYLCAKNVLIAHAKAYHLYNNEF 713
+ P + + GY + AP + + YL A N+L+AHAK +HLYN F
Sbjct: 238 DNPYVVAWHGYATGRLAPGIRGSPRLGYLVAHNLLLAHAKVWHLYNTSF 286
Score = 93.1 bits (221), Expect = 9e-19
Identities = 62/220 (28%), Positives = 105/220 (47%), Gaps = 10/220 (4%)
Frame = +3
Query: 84 FPDDFLIGTATASYQIEGAWNE-DGKGENIWDYLTHNNPAAVKDGSTGDIAANSY----H 248
FP DF G Q++ ++ +WD H++ +K SY
Sbjct: 519 FPCDFAWGVVDNYIQVDTTLSQFTDLNVYLWD--VHHSKRLIKVDGVVTKKRKSYCVDFA 576
Query: 249 NVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMIT 428
++ + +++E+ + +RFSL W+ ILP G +++N + YY + +E+++ ITP++
Sbjct: 577 AIQPQIALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNITPVVA 636
Query: 429 LF-----HWDLPQKLQELGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYE 593
L+ + LP+ L G + NP ++ F +YAR+ + G VK WIT+NEP
Sbjct: 637 LWQPMAPNQGLPRLLARQGAWENPYTALAFAEYARLCFQELGHHVKLWITMNEP------ 690
Query: 594 GYGSVHKAPILXATAIGTYLCAKNVLIAHAKAYHLYNNEF 713
T TY N+L AHA A+H+YN +F
Sbjct: 691 ------------YTRNMTYSAGHNLLKAHALAWHVYNEKF 718
>AB009667-2|BAA24941.1| 549|Homo sapiens Klotho protein (KL)
protein.
Length = 549
Score = 210 bits (514), Expect = 3e-54
Identities = 101/229 (44%), Positives = 143/229 (62%), Gaps = 16/229 (6%)
Frame = +3
Query: 75 QRRFPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDG------------- 215
Q FPD FL +A+YQ EG W + GKG +IWD TH+ A D
Sbjct: 58 QGTFPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPL 117
Query: 216 --STGDIAANSYHNVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLI 389
+TGD+A++SY+NV RD E +RELG+ YRFS+SW+R+LP+G A N G+ YY RL+
Sbjct: 118 QPATGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLL 177
Query: 390 NEMLKYGITPMITLFHWDLPQKLQE-LGGFANPLASIWFEDYARVVYTNFGDRVKHWITI 566
+ + G+ P++TL+HWDLPQ+LQ+ GG+AN + F DYA + + +FG +VK+WITI
Sbjct: 178 ERLRELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITI 237
Query: 567 NEPREICYEGYGSVHKAPILXATAIGTYLCAKNVLIAHAKAYHLYNNEF 713
+ P + + GY + AP + + YL A N+L+AHAK +HLYN F
Sbjct: 238 DNPYVVAWHGYATGRLAPGIRGSPRLGYLVAHNLLLAHAKVWHLYNTSF 286
>AB009667-1|BAA24940.1| 1012|Homo sapiens Klotho protein (KL)
protein.
Length = 1012
Score = 210 bits (514), Expect = 3e-54
Identities = 101/229 (44%), Positives = 143/229 (62%), Gaps = 16/229 (6%)
Frame = +3
Query: 75 QRRFPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDG------------- 215
Q FPD FL +A+YQ EG W + GKG +IWD TH+ A D
Sbjct: 58 QGTFPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPL 117
Query: 216 --STGDIAANSYHNVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLI 389
+TGD+A++SY+NV RD E +RELG+ YRFS+SW+R+LP+G A N G+ YY RL+
Sbjct: 118 QPATGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLL 177
Query: 390 NEMLKYGITPMITLFHWDLPQKLQE-LGGFANPLASIWFEDYARVVYTNFGDRVKHWITI 566
+ + G+ P++TL+HWDLPQ+LQ+ GG+AN + F DYA + + +FG +VK+WITI
Sbjct: 178 ERLRELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITI 237
Query: 567 NEPREICYEGYGSVHKAPILXATAIGTYLCAKNVLIAHAKAYHLYNNEF 713
+ P + + GY + AP + + YL A N+L+AHAK +HLYN F
Sbjct: 238 DNPYVVAWHGYATGRLAPGIRGSPRLGYLVAHNLLLAHAKVWHLYNTSF 286
Score = 93.1 bits (221), Expect = 9e-19
Identities = 62/220 (28%), Positives = 105/220 (47%), Gaps = 10/220 (4%)
Frame = +3
Query: 84 FPDDFLIGTATASYQIEGAWNE-DGKGENIWDYLTHNNPAAVKDGSTGDIAANSY----H 248
FP DF G Q++ ++ +WD H++ +K SY
Sbjct: 519 FPCDFAWGVVDNYIQVDTTLSQFTDLNVYLWD--VHHSKRLIKVDGVVTKKRKSYCVDFA 576
Query: 249 NVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMIT 428
++ + +++E+ + +RFSL W+ ILP G +++N + YY + +E+++ ITP++
Sbjct: 577 AIQPQIALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNITPVVA 636
Query: 429 LF-----HWDLPQKLQELGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYE 593
L+ + LP+ L G + NP ++ F +YAR+ + G VK WIT+NEP
Sbjct: 637 LWQPMAPNQGLPRLLARQGAWENPYTALAFAEYARLCFQELGHHVKLWITMNEP------ 690
Query: 594 GYGSVHKAPILXATAIGTYLCAKNVLIAHAKAYHLYNNEF 713
T TY N+L AHA A+H+YN +F
Sbjct: 691 ------------YTRNMTYSAGHNLLKAHALAWHVYNEKF 718
>AB005142-1|BAA23382.1| 1012|Homo sapiens klotho protein.
Length = 1012
Score = 210 bits (514), Expect = 3e-54
Identities = 101/229 (44%), Positives = 143/229 (62%), Gaps = 16/229 (6%)
Frame = +3
Query: 75 QRRFPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDG------------- 215
Q FPD FL +A+YQ EG W + GKG +IWD TH+ A D
Sbjct: 58 QGTFPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPL 117
Query: 216 --STGDIAANSYHNVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLI 389
+TGD+A++SY+NV RD E +RELG+ YRFS+SW+R+LP+G A N G+ YY RL+
Sbjct: 118 QPATGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLL 177
Query: 390 NEMLKYGITPMITLFHWDLPQKLQE-LGGFANPLASIWFEDYARVVYTNFGDRVKHWITI 566
+ + G+ P++TL+HWDLPQ+LQ+ GG+AN + F DYA + + +FG +VK+WITI
Sbjct: 178 ERLRELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITI 237
Query: 567 NEPREICYEGYGSVHKAPILXATAIGTYLCAKNVLIAHAKAYHLYNNEF 713
+ P + + GY + AP + + YL A N+L+AHAK +HLYN F
Sbjct: 238 DNPYVVAWHGYATGRLAPGIRGSPRLGYLVAHNLLLAHAKVWHLYNTSF 286
Score = 93.1 bits (221), Expect = 9e-19
Identities = 62/220 (28%), Positives = 105/220 (47%), Gaps = 10/220 (4%)
Frame = +3
Query: 84 FPDDFLIGTATASYQIEGAWNE-DGKGENIWDYLTHNNPAAVKDGSTGDIAANSY----H 248
FP DF G Q++ ++ +WD H++ +K SY
Sbjct: 519 FPCDFAWGVVDNYIQVDTTLSQFTDLNVYLWD--VHHSKRLIKVDGVVTKKRKSYCVDFA 576
Query: 249 NVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMIT 428
++ + +++E+ + +RFSL W+ ILP G +++N + YY + +E+++ ITP++
Sbjct: 577 AIQPQIALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNITPVVA 636
Query: 429 LF-----HWDLPQKLQELGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYE 593
L+ + LP+ L G + NP ++ F +YAR+ + G VK WIT+NEP
Sbjct: 637 LWQPMAPNQGLPRLLARQGAWENPYTALAFAEYARLCFQELGHHVKLWITMNEP------ 690
Query: 594 GYGSVHKAPILXATAIGTYLCAKNVLIAHAKAYHLYNNEF 713
T TY N+L AHA A+H+YN +F
Sbjct: 691 ------------YTRNMTYSAGHNLLKAHALAWHVYNEKF 718
>BC101829-1|AAI01830.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 204 bits (499), Expect = 2e-52
Identities = 93/210 (44%), Positives = 133/210 (63%)
Frame = +3
Query: 84 FPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVERD 263
FP F ATA+YQ+EG W+ DGKG +WD TH V TGD+A SY E D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 264 VEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHWD 443
++ +++LGL YRFSLSWSR+LP G IN+ G+DYYN++I+++LK G+TP++TL+H+D
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122
Query: 444 LPQKLQELGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGYGSVHKAPI 623
LPQ L++ GG+ + F+ YA+ ++ FGDRVK WITINE + Y P
Sbjct: 123 LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPG 182
Query: 624 LXATAIGTYLCAKNVLIAHAKAYHLYNNEF 713
+ G Y A N++ AHA+++H Y++ F
Sbjct: 183 IPHFGTGGYQAAHNLIKAHARSWHSYDSLF 212
>AK222963-1|BAD96683.1| 469|Homo sapiens cytosolic beta-glucosidase
variant protein.
Length = 469
Score = 204 bits (499), Expect = 2e-52
Identities = 93/210 (44%), Positives = 133/210 (63%)
Frame = +3
Query: 84 FPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVERD 263
FP F ATA+YQ+EG W+ DGKG +WD TH V TGD+A SY E D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 264 VEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHWD 443
++ +++LGL YRFSLSWSR+LP G IN+ G+DYYN++I+++LK G+TP++TL+H+D
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122
Query: 444 LPQKLQELGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGYGSVHKAPI 623
LPQ L++ GG+ + F+ YA+ ++ FGDRVK WITINE + Y P
Sbjct: 123 LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPG 182
Query: 624 LXATAIGTYLCAKNVLIAHAKAYHLYNNEF 713
+ G Y A N++ AHA+++H Y++ F
Sbjct: 183 IPHFGTGGYQAAHNLIKAHARSWHSYDSLF 212
>AJ278964-1|CAC08178.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 204 bits (499), Expect = 2e-52
Identities = 93/210 (44%), Positives = 133/210 (63%)
Frame = +3
Query: 84 FPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVERD 263
FP F ATA+YQ+EG W+ DGKG +WD TH V TGD+A SY E D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 264 VEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHWD 443
++ +++LGL YRFSLSWSR+LP G IN+ G+DYYN++I+++LK G+TP++TL+H+D
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122
Query: 444 LPQKLQELGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGYGSVHKAPI 623
LPQ L++ GG+ + F+ YA+ ++ FGDRVK WITINE + Y P
Sbjct: 123 LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPG 182
Query: 624 LXATAIGTYLCAKNVLIAHAKAYHLYNNEF 713
+ G Y A N++ AHA+++H Y++ F
Sbjct: 183 IPHFGTGGYQAAHNLIKAHARSWHSYDSLF 212
>AF323990-1|AAL37305.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 204 bits (499), Expect = 2e-52
Identities = 93/210 (44%), Positives = 133/210 (63%)
Frame = +3
Query: 84 FPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVERD 263
FP F ATA+YQ+EG W+ DGKG +WD TH V TGD+A SY E D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 264 VEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHWD 443
++ +++LGL YRFSLSWSR+LP G IN+ G+DYYN++I+++LK G+TP++TL+H+D
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122
Query: 444 LPQKLQELGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGYGSVHKAPI 623
LPQ L++ GG+ + F+ YA+ ++ FGDRVK WITINE + Y P
Sbjct: 123 LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPG 182
Query: 624 LXATAIGTYLCAKNVLIAHAKAYHLYNNEF 713
+ G Y A N++ AHA+++H Y++ F
Sbjct: 183 IPHFGTGGYQAAHNLIKAHARSWHSYDSLF 212
>AB017913-1|BAB18741.1| 469|Homo sapiens cytosolic
beta-glucosidase-like protein-1 protein.
Length = 469
Score = 204 bits (499), Expect = 2e-52
Identities = 93/210 (44%), Positives = 133/210 (63%)
Frame = +3
Query: 84 FPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVERD 263
FP F ATA+YQ+EG W+ DGKG +WD TH V TGD+A SY E D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 264 VEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHWD 443
++ +++LGL YRFSLSWSR+LP G IN+ G+DYYN++I+++LK G+TP++TL+H+D
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122
Query: 444 LPQKLQELGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGYGSVHKAPI 623
LPQ L++ GG+ + F+ YA+ ++ FGDRVK WITINE + Y P
Sbjct: 123 LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPG 182
Query: 624 LXATAIGTYLCAKNVLIAHAKAYHLYNNEF 713
+ G Y A N++ AHA+++H Y++ F
Sbjct: 183 IPHFGTGGYQAAHNLIKAHARSWHSYDSLF 212
>AF317840-1|AAG39217.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 204 bits (497), Expect = 3e-52
Identities = 93/210 (44%), Positives = 133/210 (63%)
Frame = +3
Query: 84 FPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVERD 263
FP F ATA+YQ+EG W+ DGKG +WD TH V TGD+A SY E D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 264 VEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHWD 443
++ +++LGL YRFSLSWSR+LP G IN+ G+DYYN++I+++LK G+TP++TL+H+D
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122
Query: 444 LPQKLQELGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGYGSVHKAPI 623
LPQ L++ GG+ + F+ YA+ ++ FGDRVK WITINE + Y P
Sbjct: 123 LPQTLEDQGGWWSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPG 182
Query: 624 LXATAIGTYLCAKNVLIAHAKAYHLYNNEF 713
+ G Y A N++ AHA+++H Y++ F
Sbjct: 183 IPHFGTGGYQAAHNLIKAHARSWHSYDSLF 212
>Z92540-2|CAC94767.1| 273|Homo sapiens 179I15.1 (klotho) protein.
Length = 273
Score = 189 bits (460), Expect = 1e-47
Identities = 92/216 (42%), Positives = 133/216 (61%), Gaps = 16/216 (7%)
Frame = +3
Query: 75 QRRFPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDG------------- 215
Q FPD FL +A+YQ EG W + GKG +IWD TH+ A D
Sbjct: 58 QGTFPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPL 117
Query: 216 --STGDIAANSYHNVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLI 389
+TGD+A++SY+NV RD E +RELG+ YRFS+SW+R+LP+G A N G+ YY RL+
Sbjct: 118 QPATGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLL 177
Query: 390 NEMLKYGITPMITLFHWDLPQKLQE-LGGFANPLASIWFEDYARVVYTNFGDRVKHWITI 566
+ + G+ P++TL+HWDLPQ+LQ+ GG+AN + F DYA + + +FG +VK+WITI
Sbjct: 178 ERLRELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITI 237
Query: 567 NEPREICYEGYGSVHKAPILXATAIGTYLCAKNVLI 674
+ P + + GY + AP + + YL A N+L+
Sbjct: 238 DNPYVVAWHGYATGRLAPGIRGSPRLGYLVAHNLLL 273
>BC113653-1|AAI13654.1| 1044|Homo sapiens klotho beta protein.
Length = 1044
Score = 177 bits (432), Expect = 2e-44
Identities = 81/211 (38%), Positives = 125/211 (59%), Gaps = 1/211 (0%)
Frame = +3
Query: 84 FPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVERD 263
FP +F G T + Q+EG+W +DGKG +IWD+ H + +K+ S+ + +++SY +E+D
Sbjct: 81 FPKNFFWGIGTGALQVEGSWKKDGKGPSIWDHFIHTH---LKNVSSTNGSSDSYIFLEKD 137
Query: 264 VEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHWD 443
+ + +G+ Y+FS+SW R+ P G N G+ YY+ L++ ++ I P++TL+HWD
Sbjct: 138 LSALDFIGVSFYQFSISWPRLFPDGIVTVANAKGLQYYSTLLDALVLRNIEPIVTLYHWD 197
Query: 444 LPQKLQE-LGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGYGSVHKAP 620
LP LQE GG+ N F DYA + FGDRVK+WITI+ P + + GYG+ AP
Sbjct: 198 LPLALQEKYGGWKNDTIIDIFNDYATYCFQMFGDRVKYWITIHNPYLVAWHGYGTGMHAP 257
Query: 621 ILXATAIGTYLCAKNVLIAHAKAYHLYNNEF 713
Y N++ AH+K +H YN F
Sbjct: 258 GEKGNLAAVYTVGHNLIKAHSKVWHNYNTHF 288
Score = 107 bits (256), Expect = 5e-23
Identities = 56/160 (35%), Positives = 90/160 (56%), Gaps = 5/160 (3%)
Frame = +3
Query: 249 NVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMIT 428
N+++ +EM+ + + YRF+L W+ +LP+G + +N + YY +++E LK GI+ M+T
Sbjct: 581 NIKKQLEMLARMKVTHYRFALDWASVLPTGNLSAVNRQALRYYRCVVSEGLKLGISAMVT 640
Query: 429 LF-----HWDLPQKLQELGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYE 593
L+ H LP+ L G+ NP + F+ YA + + GD VK WITINEP +
Sbjct: 641 LYYPTHAHLGLPEPLLHADGWLNPSTAEAFQAYAGLCFQELGDLVKLWITINEPNRL--- 697
Query: 594 GYGSVHKAPILXATAIGTYLCAKNVLIAHAKAYHLYNNEF 713
+ I + TY A N+L+AHA A+ LY+ +F
Sbjct: 698 -------SDIYNRSGNDTYGAAHNLLVAHALAWRLYDRQF 730
>BC104871-1|AAI04872.1| 1044|Homo sapiens klotho beta protein.
Length = 1044
Score = 177 bits (432), Expect = 2e-44
Identities = 81/211 (38%), Positives = 125/211 (59%), Gaps = 1/211 (0%)
Frame = +3
Query: 84 FPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVERD 263
FP +F G T + Q+EG+W +DGKG +IWD+ H + +K+ S+ + +++SY +E+D
Sbjct: 81 FPKNFFWGIGTGALQVEGSWKKDGKGPSIWDHFIHTH---LKNVSSTNGSSDSYIFLEKD 137
Query: 264 VEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHWD 443
+ + +G+ Y+FS+SW R+ P G N G+ YY+ L++ ++ I P++TL+HWD
Sbjct: 138 LSALDFIGVSFYQFSISWPRLFPDGIVTVANAKGLQYYSTLLDALVLRNIEPIVTLYHWD 197
Query: 444 LPQKLQE-LGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGYGSVHKAP 620
LP LQE GG+ N F DYA + FGDRVK+WITI+ P + + GYG+ AP
Sbjct: 198 LPLALQEKYGGWKNDTIIDIFNDYATYCFQMFGDRVKYWITIHNPYLVAWHGYGTGMHAP 257
Query: 621 ILXATAIGTYLCAKNVLIAHAKAYHLYNNEF 713
Y N++ AH+K +H YN F
Sbjct: 258 GEKGNLAAVYTVGHNLIKAHSKVWHNYNTHF 288
Score = 107 bits (256), Expect = 5e-23
Identities = 56/160 (35%), Positives = 90/160 (56%), Gaps = 5/160 (3%)
Frame = +3
Query: 249 NVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMIT 428
N+++ +EM+ + + YRF+L W+ +LP+G + +N + YY +++E LK GI+ M+T
Sbjct: 581 NIKKQLEMLARMKVTHYRFALDWASVLPTGNLSAVNRQALRYYRCVVSEGLKLGISAMVT 640
Query: 429 LF-----HWDLPQKLQELGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYE 593
L+ H LP+ L G+ NP + F+ YA + + GD VK WITINEP +
Sbjct: 641 LYYPTHAHLGLPEPLLHADGWLNPSTAEAFQAYAGLCFQELGDLVKLWITINEPNRL--- 697
Query: 594 GYGSVHKAPILXATAIGTYLCAKNVLIAHAKAYHLYNNEF 713
+ I + TY A N+L+AHA A+ LY+ +F
Sbjct: 698 -------SDIYNRSGNDTYGAAHNLLVAHALAWRLYDRQF 730
>AB079373-1|BAC56857.1| 1044|Homo sapiens klotho beta like protein
protein.
Length = 1044
Score = 177 bits (432), Expect = 2e-44
Identities = 81/211 (38%), Positives = 125/211 (59%), Gaps = 1/211 (0%)
Frame = +3
Query: 84 FPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVERD 263
FP +F G T + Q+EG+W +DGKG +IWD+ H + +K+ S+ + +++SY +E+D
Sbjct: 81 FPKNFFWGIGTGALQVEGSWKKDGKGPSIWDHFIHTH---LKNVSSTNGSSDSYIFLEKD 137
Query: 264 VEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHWD 443
+ + +G+ Y+FS+SW R+ P G N G+ YY+ L++ ++ I P++TL+HWD
Sbjct: 138 LSALDFIGVSFYQFSISWPRLFPDGIVTVANAKGLQYYSTLLDALVLRNIEPIVTLYHWD 197
Query: 444 LPQKLQE-LGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGYGSVHKAP 620
LP LQE GG+ N F DYA + FGDRVK+WITI+ P + + GYG+ AP
Sbjct: 198 LPLALQEKYGGWKNDTIIDIFNDYATYCFQMFGDRVKYWITIHNPYLVAWHGYGTGMHAP 257
Query: 621 ILXATAIGTYLCAKNVLIAHAKAYHLYNNEF 713
Y N++ AH+K +H YN F
Sbjct: 258 GEKGNLAAVYTVGHNLIKAHSKVWHNYNTHF 288
Score = 107 bits (256), Expect = 5e-23
Identities = 56/160 (35%), Positives = 90/160 (56%), Gaps = 5/160 (3%)
Frame = +3
Query: 249 NVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMIT 428
N+++ +EM+ + + YRF+L W+ +LP+G + +N + YY +++E LK GI+ M+T
Sbjct: 581 NIKKQLEMLARMKVTHYRFALDWASVLPTGNLSAVNRQALRYYRCVVSEGLKLGISAMVT 640
Query: 429 LF-----HWDLPQKLQELGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYE 593
L+ H LP+ L G+ NP + F+ YA + + GD VK WITINEP +
Sbjct: 641 LYYPTHAHLGLPEPLLHADGWLNPSTAEAFQAYAGLCFQELGDLVKLWITINEPNRL--- 697
Query: 594 GYGSVHKAPILXATAIGTYLCAKNVLIAHAKAYHLYNNEF 713
+ I + TY A N+L+AHA A+ LY+ +F
Sbjct: 698 -------SDIYNRSGNDTYGAAHNLLVAHALAWRLYDRQF 730
>BC109377-1|AAI09378.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 99 bits (238), Expect = 8e-21
Identities = 45/95 (47%), Positives = 58/95 (61%)
Frame = +3
Query: 84 FPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVERD 263
FP F ATA+YQ+EG W+ DGKG +WD TH V TGD+A SY E D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 264 VEMMRELGLDVYRFSLSWSRILPSGFANEINEAGV 368
++ +++LGL YRFSLSWSR+LP G IN+ +
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKAI 97
>BC029362-1|AAH29362.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 99 bits (238), Expect = 8e-21
Identities = 45/95 (47%), Positives = 58/95 (61%)
Frame = +3
Query: 84 FPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVERD 263
FP F ATA+YQ+EG W+ DGKG +WD TH V TGD+A SY E D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 264 VEMMRELGLDVYRFSLSWSRILPSGFANEINEAGV 368
++ +++LGL YRFSLSWSR+LP G IN+ +
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKAI 97
>BC070188-1|AAH70188.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 99.1 bits (236), Expect = 1e-20
Identities = 45/95 (47%), Positives = 58/95 (61%)
Frame = +3
Query: 84 FPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVERD 263
FP F ATA+YQ+EG W+ DGKG +WD TH V TGD+A SY E D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGLCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 264 VEMMRELGLDVYRFSLSWSRILPSGFANEINEAGV 368
++ +++LGL YRFSLSWSR+LP G IN+ +
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKAI 97
>Z84483-1|CAC94773.1| 739|Homo sapiens 46H23.1 (Klotho) protein.
Length = 739
Score = 93.1 bits (221), Expect = 9e-19
Identities = 62/220 (28%), Positives = 105/220 (47%), Gaps = 10/220 (4%)
Frame = +3
Query: 84 FPDDFLIGTATASYQIEGAWNE-DGKGENIWDYLTHNNPAAVKDGSTGDIAANSY----H 248
FP DF G Q++ ++ +WD H++ +K SY
Sbjct: 246 FPCDFAWGVVDNYIQVDTTLSQFTDLNVYLWD--VHHSKRLIKVDGVVTKKRKSYCVDFA 303
Query: 249 NVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMIT 428
++ + +++E+ + +RFSL W+ ILP G +++N + YY + +E+++ ITP++
Sbjct: 304 AIQPQIALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNITPVVA 363
Query: 429 LF-----HWDLPQKLQELGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYE 593
L+ + LP+ L G + NP ++ F +YAR+ + G VK WIT+NEP
Sbjct: 364 LWQPMAPNQGLPRLLARQGAWENPYTALAFAEYARLCFQELGHHVKLWITMNEP------ 417
Query: 594 GYGSVHKAPILXATAIGTYLCAKNVLIAHAKAYHLYNNEF 713
T TY N+L AHA A+H+YN +F
Sbjct: 418 ------------YTRNMTYSAGHNLLKAHALAWHVYNEKF 445
>BT007435-1|AAP36103.1| 441|Homo sapiens G protein-coupled
receptor, family C, group 5, member C protein.
Length = 441
Score = 31.9 bits (69), Expect = 2.3
Identities = 14/51 (27%), Positives = 25/51 (49%)
Frame = +3
Query: 93 DFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSY 245
D ++ ATA+ Q+ G+ N + E+++ +H KDG + N Y
Sbjct: 388 DIILPRATANSQVMGSANSTLRAEDMYSAQSHQAATPPKDGKNSQVFRNPY 438
>BC125081-1|AAI25082.1| 486|Homo sapiens G protein-coupled
receptor, family C, group 5, member C protein.
Length = 486
Score = 31.9 bits (69), Expect = 2.3
Identities = 14/51 (27%), Positives = 25/51 (49%)
Frame = +3
Query: 93 DFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSY 245
D ++ ATA+ Q+ G+ N + E+++ +H KDG + N Y
Sbjct: 433 DIILPRATANSQVMGSANSTLRAEDMYSAQSHQAATPPKDGKNSQVFRNPY 483
>BC125080-1|AAI25081.1| 486|Homo sapiens G protein-coupled
receptor, family C, group 5, member C protein.
Length = 486
Score = 31.9 bits (69), Expect = 2.3
Identities = 14/51 (27%), Positives = 25/51 (49%)
Frame = +3
Query: 93 DFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSY 245
D ++ ATA+ Q+ G+ N + E+++ +H KDG + N Y
Sbjct: 433 DIILPRATANSQVMGSANSTLRAEDMYSAQSHQAATPPKDGKNSQVFRNPY 483
>BC110848-1|AAI10849.1| 486|Homo sapiens G protein-coupled
receptor, family C, group 5, member C protein.
Length = 486
Score = 31.9 bits (69), Expect = 2.3
Identities = 14/51 (27%), Positives = 25/51 (49%)
Frame = +3
Query: 93 DFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSY 245
D ++ ATA+ Q+ G+ N + E+++ +H KDG + N Y
Sbjct: 433 DIILPRATANSQVMGSANSTLRAEDMYSAQSHQAATPPKDGKNSQVFRNPY 483
>BC016860-1|AAH16860.2| 448|Homo sapiens GPRC5C protein protein.
Length = 448
Score = 31.9 bits (69), Expect = 2.3
Identities = 14/51 (27%), Positives = 25/51 (49%)
Frame = +3
Query: 93 DFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSY 245
D ++ ATA+ Q+ G+ N + E+++ +H KDG + N Y
Sbjct: 395 DIILPRATANSQVMGSANSTLRAEDMYSAQSHQAATPPKDGKNSQVFRNPY 445
>AK075397-1|BAC11595.1| 441|Homo sapiens protein ( Homo sapiens
cDNA PSEC0087 fis, clone PLACE1001022, highly similar to
G protein-coupled receptor, family C, group 5, member C
isoform ).
Length = 441
Score = 31.9 bits (69), Expect = 2.3
Identities = 14/51 (27%), Positives = 25/51 (49%)
Frame = +3
Query: 93 DFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSY 245
D ++ ATA+ Q+ G+ N + E+++ +H KDG + N Y
Sbjct: 388 DIILPRATANSQVMGSANSTLRAEDMYSAQSHQAATPPKDGKNSQVFRNPY 438
>AJ276102-1|CAC00633.1| 441|Homo sapiens GPRC5C protein.
Length = 441
Score = 31.9 bits (69), Expect = 2.3
Identities = 14/51 (27%), Positives = 25/51 (49%)
Frame = +3
Query: 93 DFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSY 245
D ++ ATA+ Q+ G+ N + E+++ +H KDG + N Y
Sbjct: 388 DIILPRATANSQVMGSANSTLRAEDMYSAQSHQAATPPKDGKNSQVFRNPY 438
>AF207989-1|AAF72870.1| 441|Homo sapiens orphan G-protein coupled
receptor protein.
Length = 441
Score = 31.9 bits (69), Expect = 2.3
Identities = 14/51 (27%), Positives = 25/51 (49%)
Frame = +3
Query: 93 DFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSY 245
D ++ ATA+ Q+ G+ N + E+++ +H KDG + N Y
Sbjct: 388 DIILPRATANSQVMGSANSTLRAEDMYSAQSHQAATPPKDGKNSQVFRNPY 438
>BC034469-1|AAH34469.1| 849|Homo sapiens coiled-coil domain
containing 87 protein.
Length = 849
Score = 30.3 bits (65), Expect = 7.2
Identities = 12/21 (57%), Positives = 15/21 (71%)
Frame = +1
Query: 67 PSSREGFRMTSSSGLPPPPTR 129
PS REG+R+ GLPP P+R
Sbjct: 313 PSLREGWRLADELGLPPLPSR 333
>AK001648-1|BAA91808.1| 849|Homo sapiens protein ( Homo sapiens
cDNA FLJ10786 fis, clone NT2RP4000480. ).
Length = 849
Score = 30.3 bits (65), Expect = 7.2
Identities = 12/21 (57%), Positives = 15/21 (71%)
Frame = +1
Query: 67 PSSREGFRMTSSSGLPPPPTR 129
PS REG+R+ GLPP P+R
Sbjct: 313 PSLREGWRLADELGLPPLPSR 333
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 103,354,579
Number of Sequences: 237096
Number of extensions: 2137002
Number of successful extensions: 5120
Number of sequences better than 10.0: 33
Number of HSP's better than 10.0 without gapping: 4819
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5084
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8343197486
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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