Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= bmmt4k13
(744 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X69433-1|CAA49208.1| 452|Homo sapiens isocitrate dehydrogenase... 297 2e-80
BC071828-1|AAH71828.1| 452|Homo sapiens isocitrate dehydrogenas... 297 2e-80
BC009244-1|AAH09244.1| 452|Homo sapiens isocitrate dehydrogenas... 297 2e-80
AK222916-1|BAD96636.1| 452|Homo sapiens isocitrate dehydrogenas... 297 2e-80
CR541695-1|CAG46496.1| 414|Homo sapiens IDH1 protein. 283 6e-76
CR536499-1|CAG38738.1| 414|Homo sapiens IDH1 protein. 283 6e-76
BC093020-1|AAH93020.1| 414|Homo sapiens isocitrate dehydrogenas... 283 6e-76
BC012846-1|AAH12846.1| 414|Homo sapiens IDH1 protein protein. 283 6e-76
AF113917-1|AAD29284.1| 414|Homo sapiens NADP+-dependent isocitr... 283 6e-76
AF020038-1|AAD02918.1| 414|Homo sapiens NADP-dependent isocitra... 283 6e-76
AC016697-3|AAX93221.1| 414|Homo sapiens unknown protein. 283 6e-76
BX537411-1|CAD97653.1| 414|Homo sapiens hypothetical protein pr... 280 3e-75
CR533522-1|CAG38553.1| 414|Homo sapiens IDH1 protein. 279 1e-74
DQ403082-1|ABD77215.1| 371|Homo sapiens isocitrate dehydrogenas... 249 7e-66
U52144-1|AAC50455.1| 419|Homo sapiens isocitrate dehydrogenase ... 240 3e-63
U62389-1|AAB17375.1| 154|Homo sapiens putative cytosolic NADP-d... 134 2e-31
AK090454-1|BAC03435.1| 708|Homo sapiens FLJ00375 protein protein. 35 0.27
>X69433-1|CAA49208.1| 452|Homo sapiens isocitrate dehydrogenase
(NADP+) protein.
Length = 452
Score = 297 bits (730), Expect = 2e-80
Identities = 138/199 (69%), Positives = 160/199 (80%), Gaps = 1/199 (0%)
Frame = +2
Query: 149 RNYGTAKRVVAAKPVVEMDGDEMTRIIWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQ 328
R + KR+ AKPVVEMDGDEMTRIIW IKE+LI P+V + YFDLGLP+RD TDDQ
Sbjct: 36 RRHYADKRIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQ 95
Query: 329 VTIDSAHAILKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQ 508
VTIDSA A K++V +KCATITPDE RVEEFKLKKMW SPNGTIRNILGGTVFREPI+C+
Sbjct: 96 VTIDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICK 155
Query: 509 SIPRVVPGWTKPIVIGRHAHGDQYKAQDFVVPKPGKVELVYTTQDGT-TERRVLYDFKTP 685
+IPR+VPGWTKPI IGRHAHGDQYKA DFV + G ++V+T +DG+ + +Y+F
Sbjct: 156 NIPRLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAG 215
Query: 686 GVAMGMYNTDESIRSFAHS 742
GV MGMYNTDESI FAHS
Sbjct: 216 GVGMGMYNTDESISGFAHS 234
>BC071828-1|AAH71828.1| 452|Homo sapiens isocitrate dehydrogenase 2
(NADP+), mitochondrial protein.
Length = 452
Score = 297 bits (730), Expect = 2e-80
Identities = 138/199 (69%), Positives = 160/199 (80%), Gaps = 1/199 (0%)
Frame = +2
Query: 149 RNYGTAKRVVAAKPVVEMDGDEMTRIIWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQ 328
R + KR+ AKPVVEMDGDEMTRIIW IKE+LI P+V + YFDLGLP+RD TDDQ
Sbjct: 36 RRHYADKRIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQ 95
Query: 329 VTIDSAHAILKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQ 508
VTIDSA A K++V +KCATITPDE RVEEFKLKKMW SPNGTIRNILGGTVFREPI+C+
Sbjct: 96 VTIDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICK 155
Query: 509 SIPRVVPGWTKPIVIGRHAHGDQYKAQDFVVPKPGKVELVYTTQDGT-TERRVLYDFKTP 685
+IPR+VPGWTKPI IGRHAHGDQYKA DFV + G ++V+T +DG+ + +Y+F
Sbjct: 156 NIPRLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAG 215
Query: 686 GVAMGMYNTDESIRSFAHS 742
GV MGMYNTDESI FAHS
Sbjct: 216 GVGMGMYNTDESISGFAHS 234
>BC009244-1|AAH09244.1| 452|Homo sapiens isocitrate dehydrogenase 2
(NADP+), mitochondrial protein.
Length = 452
Score = 297 bits (730), Expect = 2e-80
Identities = 138/199 (69%), Positives = 160/199 (80%), Gaps = 1/199 (0%)
Frame = +2
Query: 149 RNYGTAKRVVAAKPVVEMDGDEMTRIIWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQ 328
R + KR+ AKPVVEMDGDEMTRIIW IKE+LI P+V + YFDLGLP+RD TDDQ
Sbjct: 36 RRHYADKRIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQ 95
Query: 329 VTIDSAHAILKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQ 508
VTIDSA A K++V +KCATITPDE RVEEFKLKKMW SPNGTIRNILGGTVFREPI+C+
Sbjct: 96 VTIDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICK 155
Query: 509 SIPRVVPGWTKPIVIGRHAHGDQYKAQDFVVPKPGKVELVYTTQDGT-TERRVLYDFKTP 685
+IPR+VPGWTKPI IGRHAHGDQYKA DFV + G ++V+T +DG+ + +Y+F
Sbjct: 156 NIPRLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAG 215
Query: 686 GVAMGMYNTDESIRSFAHS 742
GV MGMYNTDESI FAHS
Sbjct: 216 GVGMGMYNTDESISGFAHS 234
>AK222916-1|BAD96636.1| 452|Homo sapiens isocitrate dehydrogenase 2
(NADP+), mitochondrial precursor variant protein.
Length = 452
Score = 297 bits (730), Expect = 2e-80
Identities = 138/199 (69%), Positives = 160/199 (80%), Gaps = 1/199 (0%)
Frame = +2
Query: 149 RNYGTAKRVVAAKPVVEMDGDEMTRIIWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQ 328
R + KR+ AKPVVEMDGDEMTRIIW IKE+LI P+V + YFDLGLP+RD TDDQ
Sbjct: 36 RRHYADKRIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQ 95
Query: 329 VTIDSAHAILKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQ 508
VTIDSA A K++V +KCATITPDE RVEEFKLKKMW SPNGTIRNILGGTVFREPI+C+
Sbjct: 96 VTIDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICK 155
Query: 509 SIPRVVPGWTKPIVIGRHAHGDQYKAQDFVVPKPGKVELVYTTQDGT-TERRVLYDFKTP 685
+IPR+VPGWTKPI IGRHAHGDQYKA DFV + G ++V+T +DG+ + +Y+F
Sbjct: 156 NIPRLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAG 215
Query: 686 GVAMGMYNTDESIRSFAHS 742
GV MGMYNTDESI FAHS
Sbjct: 216 GVGMGMYNTDESISGFAHS 234
>CR541695-1|CAG46496.1| 414|Homo sapiens IDH1 protein.
Length = 414
Score = 283 bits (693), Expect = 6e-76
Identities = 131/191 (68%), Positives = 159/191 (83%), Gaps = 2/191 (1%)
Frame = +2
Query: 176 VAAKPVVEMDGDEMTRIIWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQVTIDSAHAI 355
++ VVEM GDEMTRIIW IKE+LIFPYV++D +DLG+ +RDAT+DQVT D+A AI
Sbjct: 5 ISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAI 64
Query: 356 LKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQSIPRVVPGW 535
KHNVG+KCATITPDE+RVEEFKLK+MW SPNGTIRNILGGTVFRE I+C++IPR+V GW
Sbjct: 65 KKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGW 124
Query: 536 TKPIVIGRHAHGDQYKAQDFVVPKPGKVELVYTTQDGTTE-RRVLYDFKT-PGVAMGMYN 709
KPI+IGRHA+GDQY+A DFVVP PGKVE+ YT DGT + ++++F+ GVAMGMYN
Sbjct: 125 VKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYN 184
Query: 710 TDESIRSFAHS 742
D+SI FAHS
Sbjct: 185 QDKSIEDFAHS 195
>CR536499-1|CAG38738.1| 414|Homo sapiens IDH1 protein.
Length = 414
Score = 283 bits (693), Expect = 6e-76
Identities = 131/191 (68%), Positives = 159/191 (83%), Gaps = 2/191 (1%)
Frame = +2
Query: 176 VAAKPVVEMDGDEMTRIIWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQVTIDSAHAI 355
++ VVEM GDEMTRIIW IKE+LIFPYV++D +DLG+ +RDAT+DQVT D+A AI
Sbjct: 5 ISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAI 64
Query: 356 LKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQSIPRVVPGW 535
KHNVG+KCATITPDE+RVEEFKLK+MW SPNGTIRNILGGTVFRE I+C++IPR+V GW
Sbjct: 65 KKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGW 124
Query: 536 TKPIVIGRHAHGDQYKAQDFVVPKPGKVELVYTTQDGTTE-RRVLYDFKT-PGVAMGMYN 709
KPI+IGRHA+GDQY+A DFVVP PGKVE+ YT DGT + ++++F+ GVAMGMYN
Sbjct: 125 VKPIIIGRHAYGDQYRATDFVVPGPGKVEMTYTPSDGTQKVTYLVHNFEEGGGVAMGMYN 184
Query: 710 TDESIRSFAHS 742
D+SI FAHS
Sbjct: 185 QDKSIEDFAHS 195
>BC093020-1|AAH93020.1| 414|Homo sapiens isocitrate dehydrogenase 1
(NADP+), soluble protein.
Length = 414
Score = 283 bits (693), Expect = 6e-76
Identities = 131/191 (68%), Positives = 159/191 (83%), Gaps = 2/191 (1%)
Frame = +2
Query: 176 VAAKPVVEMDGDEMTRIIWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQVTIDSAHAI 355
++ VVEM GDEMTRIIW IKE+LIFPYV++D +DLG+ +RDAT+DQVT D+A AI
Sbjct: 5 ISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAI 64
Query: 356 LKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQSIPRVVPGW 535
KHNVG+KCATITPDE+RVEEFKLK+MW SPNGTIRNILGGTVFRE I+C++IPR+V GW
Sbjct: 65 KKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGW 124
Query: 536 TKPIVIGRHAHGDQYKAQDFVVPKPGKVELVYTTQDGTTE-RRVLYDFKT-PGVAMGMYN 709
KPI+IGRHA+GDQY+A DFVVP PGKVE+ YT DGT + ++++F+ GVAMGMYN
Sbjct: 125 VKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYN 184
Query: 710 TDESIRSFAHS 742
D+SI FAHS
Sbjct: 185 QDKSIEDFAHS 195
>BC012846-1|AAH12846.1| 414|Homo sapiens IDH1 protein protein.
Length = 414
Score = 283 bits (693), Expect = 6e-76
Identities = 131/191 (68%), Positives = 159/191 (83%), Gaps = 2/191 (1%)
Frame = +2
Query: 176 VAAKPVVEMDGDEMTRIIWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQVTIDSAHAI 355
++ VVEM GDEMTRIIW IKE+LIFPYV++D +DLG+ +RDAT+DQVT D+A AI
Sbjct: 5 ISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAI 64
Query: 356 LKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQSIPRVVPGW 535
KHNVG+KCATITPDE+RVEEFKLK+MW SPNGTIRNILGGTVFRE I+C++IPR+V GW
Sbjct: 65 KKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGW 124
Query: 536 TKPIVIGRHAHGDQYKAQDFVVPKPGKVELVYTTQDGTTE-RRVLYDFKT-PGVAMGMYN 709
KPI+IGRHA+GDQY+A DFVVP PGKVE+ YT DGT + ++++F+ GVAMGMYN
Sbjct: 125 VKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYN 184
Query: 710 TDESIRSFAHS 742
D+SI FAHS
Sbjct: 185 QDKSIEDFAHS 195
>AF113917-1|AAD29284.1| 414|Homo sapiens NADP+-dependent isocitrate
dehydrogenase protein.
Length = 414
Score = 283 bits (693), Expect = 6e-76
Identities = 131/191 (68%), Positives = 159/191 (83%), Gaps = 2/191 (1%)
Frame = +2
Query: 176 VAAKPVVEMDGDEMTRIIWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQVTIDSAHAI 355
++ VVEM GDEMTRIIW IKE+LIFPYV++D +DLG+ +RDAT+DQVT D+A AI
Sbjct: 5 ISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAI 64
Query: 356 LKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQSIPRVVPGW 535
KHNVG+KCATITPDE+RVEEFKLK+MW SPNGTIRNILGGTVFRE I+C++IPR+V GW
Sbjct: 65 KKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGW 124
Query: 536 TKPIVIGRHAHGDQYKAQDFVVPKPGKVELVYTTQDGTTE-RRVLYDFKT-PGVAMGMYN 709
KPI+IGRHA+GDQY+A DFVVP PGKVE+ YT DGT + ++++F+ GVAMGMYN
Sbjct: 125 VKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYN 184
Query: 710 TDESIRSFAHS 742
D+SI FAHS
Sbjct: 185 QDKSIEDFAHS 195
>AF020038-1|AAD02918.1| 414|Homo sapiens NADP-dependent isocitrate
dehydrogenase protein.
Length = 414
Score = 283 bits (693), Expect = 6e-76
Identities = 131/191 (68%), Positives = 159/191 (83%), Gaps = 2/191 (1%)
Frame = +2
Query: 176 VAAKPVVEMDGDEMTRIIWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQVTIDSAHAI 355
++ VVEM GDEMTRIIW IKE+LIFPYV++D +DLG+ +RDAT+DQVT D+A AI
Sbjct: 5 ISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAI 64
Query: 356 LKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQSIPRVVPGW 535
KHNVG+KCATITPDE+RVEEFKLK+MW SPNGTIRNILGGTVFRE I+C++IPR+V GW
Sbjct: 65 KKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGW 124
Query: 536 TKPIVIGRHAHGDQYKAQDFVVPKPGKVELVYTTQDGTTE-RRVLYDFKT-PGVAMGMYN 709
KPI+IGRHA+GDQY+A DFVVP PGKVE+ YT DGT + ++++F+ GVAMGMYN
Sbjct: 125 VKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYN 184
Query: 710 TDESIRSFAHS 742
D+SI FAHS
Sbjct: 185 QDKSIEDFAHS 195
>AC016697-3|AAX93221.1| 414|Homo sapiens unknown protein.
Length = 414
Score = 283 bits (693), Expect = 6e-76
Identities = 131/191 (68%), Positives = 159/191 (83%), Gaps = 2/191 (1%)
Frame = +2
Query: 176 VAAKPVVEMDGDEMTRIIWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQVTIDSAHAI 355
++ VVEM GDEMTRIIW IKE+LIFPYV++D +DLG+ +RDAT+DQVT D+A AI
Sbjct: 5 ISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAI 64
Query: 356 LKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQSIPRVVPGW 535
KHNVG+KCATITPDE+RVEEFKLK+MW SPNGTIRNILGGTVFRE I+C++IPR+V GW
Sbjct: 65 KKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGW 124
Query: 536 TKPIVIGRHAHGDQYKAQDFVVPKPGKVELVYTTQDGTTE-RRVLYDFKT-PGVAMGMYN 709
KPI+IGRHA+GDQY+A DFVVP PGKVE+ YT DGT + ++++F+ GVAMGMYN
Sbjct: 125 VKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYN 184
Query: 710 TDESIRSFAHS 742
D+SI FAHS
Sbjct: 185 QDKSIEDFAHS 195
>BX537411-1|CAD97653.1| 414|Homo sapiens hypothetical protein
protein.
Length = 414
Score = 280 bits (687), Expect = 3e-75
Identities = 131/191 (68%), Positives = 154/191 (80%), Gaps = 2/191 (1%)
Frame = +2
Query: 176 VAAKPVVEMDGDEMTRIIWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQVTIDSAHAI 355
++ VVEM GDEMTRIIW IKE+LIFPYV++D +DLG+ +RDAT+DQVT D+A AI
Sbjct: 5 ISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAI 64
Query: 356 LKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQSIPRVVPGW 535
KHNVG+KCATITPDE+RVEEFKLK+MW SPNGTIRNILGGTVFRE I+C++IPR+V GW
Sbjct: 65 KKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGW 124
Query: 536 TKPIVIGRHAHGDQYKAQDFVVPKPGKVELVYTTQDGTTERRVLYDFKT--PGVAMGMYN 709
KPI+IGRHA+GDQY+A DFVVP PGKVE+ YT DGT + L GVAMGMYN
Sbjct: 125 VKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNSEGGGGVAMGMYN 184
Query: 710 TDESIRSFAHS 742
D+SI FAHS
Sbjct: 185 QDKSIEDFAHS 195
>CR533522-1|CAG38553.1| 414|Homo sapiens IDH1 protein.
Length = 414
Score = 279 bits (683), Expect = 1e-74
Identities = 129/191 (67%), Positives = 158/191 (82%), Gaps = 2/191 (1%)
Frame = +2
Query: 176 VAAKPVVEMDGDEMTRIIWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQVTIDSAHAI 355
++ VVEM GDEMTRIIW IKE+LI PYV++D +DLG+ +RDAT+DQVT D+A AI
Sbjct: 5 ISGGSVVEMQGDEMTRIIWELIKEKLIIPYVELDLHSYDLGIENRDATNDQVTKDAAEAI 64
Query: 356 LKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQSIPRVVPGW 535
KHNVG+KCATITPDE+RVEEFKLK+MW SPNGTIRNILGGTVFRE I+C++IPR+V GW
Sbjct: 65 KKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGW 124
Query: 536 TKPIVIGRHAHGDQYKAQDFVVPKPGKVELVYTTQDGTTE-RRVLYDFKT-PGVAMGMYN 709
+PI+IGRHA+GDQY+A DFVVP PGKVE+ YT DGT + ++++F+ GVAMGMYN
Sbjct: 125 VEPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYN 184
Query: 710 TDESIRSFAHS 742
D+SI FAHS
Sbjct: 185 QDKSIEDFAHS 195
>DQ403082-1|ABD77215.1| 371|Homo sapiens isocitrate dehydrogenase 1
protein.
Length = 371
Score = 249 bits (610), Expect = 7e-66
Identities = 115/166 (69%), Positives = 140/166 (84%), Gaps = 2/166 (1%)
Frame = +2
Query: 251 LIFPYVKVDCLYFDLGLPHRDATDDQVTIDSAHAILKHNVGIKCATITPDEQRVEEFKLK 430
LIFPYV++D +DLG+ +RDAT+DQVT D+A AI KHNVG+KCATITPDE+RVEEFKLK
Sbjct: 1 LIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFKLK 60
Query: 431 KMWLSPNGTIRNILGGTVFREPILCQSIPRVVPGWTKPIVIGRHAHGDQYKAQDFVVPKP 610
+MW SPNGTIRNILGGTVFRE I+C++IPR+V GW KPI+IGRHA+GDQY+A DFVVP P
Sbjct: 61 QMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGP 120
Query: 611 GKVELVYTTQDGTTE-RRVLYDFKT-PGVAMGMYNTDESIRSFAHS 742
GKVE+ YT DGT + ++++F+ GVAMGMYN D+SI FAHS
Sbjct: 121 GKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHS 166
>U52144-1|AAC50455.1| 419|Homo sapiens isocitrate dehydrogenase
protein.
Length = 419
Score = 240 bits (588), Expect = 3e-63
Identities = 111/158 (70%), Positives = 128/158 (81%), Gaps = 1/158 (0%)
Frame = +2
Query: 272 VDCLYFDLGLPHRDATDDQVTIDSAHAILKHNVGIKCATITPDEQRVEEFKLKKMWLSPN 451
V YFDLGLP+RD TDDQVTIDSA A K++V +KCATITPDE RVEEFKLKKMW SPN
Sbjct: 44 VQLKYFDLGLPNRDQTDDQVTIDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPN 103
Query: 452 GTIRNILGGTVFREPILCQSIPRVVPGWTKPIVIGRHAHGDQYKAQDFVVPKPGKVELVY 631
GTIRNI GGTVFREPI+C++IPR+VPGWTKPI IGRHAHGDQYKA DFV + G ++V+
Sbjct: 104 GTIRNIHGGTVFREPIICKNIPRLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVF 163
Query: 632 TTQDGT-TERRVLYDFKTPGVAMGMYNTDESIRSFAHS 742
T +DG+ + +Y+F GV MGMYNTDESI FAHS
Sbjct: 164 TPKDGSGVKEWEVYNFPAGGVGMGMYNTDESISGFAHS 201
>U62389-1|AAB17375.1| 154|Homo sapiens putative cytosolic
NADP-dependent isocitrate dehydrogenase protein.
Length = 154
Score = 134 bits (325), Expect = 2e-31
Identities = 62/96 (64%), Positives = 77/96 (80%), Gaps = 2/96 (2%)
Frame = +2
Query: 461 RNILGGTVFREPILCQSIPRVVPGWTKPIVIGRHAHGDQYKAQDFVVPKPGKVELVYTTQ 640
RNILGGTVF E I+C++IPR+V GW KPI+IGRHA+GDQY+A DFVVP PGKVE+ YT
Sbjct: 1 RNILGGTVFXEAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPS 60
Query: 641 DGTTE-RRVLYDFKT-PGVAMGMYNTDESIRSFAHS 742
DGT + ++++F+ GVAMGMYN D+SI FAHS
Sbjct: 61 DGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHS 96
>AK090454-1|BAC03435.1| 708|Homo sapiens FLJ00375 protein protein.
Length = 708
Score = 35.1 bits (77), Expect = 0.27
Identities = 15/43 (34%), Positives = 21/43 (48%)
Frame = +2
Query: 515 PRVVPGWTKPIVIGRHAHGDQYKAQDFVVPKPGKVELVYTTQD 643
PR GW +P + H H DQ +P PGK +L+ +D
Sbjct: 20 PRAFKGWARPWLAQCHLHADQQPRAMHRMPDPGKFKLLEQARD 62
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 113,105,717
Number of Sequences: 237096
Number of extensions: 2388718
Number of successful extensions: 4767
Number of sequences better than 10.0: 17
Number of HSP's better than 10.0 without gapping: 4636
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4751
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8903143626
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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