Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= bmmt3b24
(710 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X69433-1|CAA49208.1| 452|Homo sapiens isocitrate dehydrogenase... 279 5e-75
BC071828-1|AAH71828.1| 452|Homo sapiens isocitrate dehydrogenas... 279 5e-75
BC009244-1|AAH09244.1| 452|Homo sapiens isocitrate dehydrogenas... 279 5e-75
AK222916-1|BAD96636.1| 452|Homo sapiens isocitrate dehydrogenas... 279 5e-75
CR541695-1|CAG46496.1| 414|Homo sapiens IDH1 protein. 268 1e-71
CR536499-1|CAG38738.1| 414|Homo sapiens IDH1 protein. 268 1e-71
BC093020-1|AAH93020.1| 414|Homo sapiens isocitrate dehydrogenas... 268 1e-71
BC012846-1|AAH12846.1| 414|Homo sapiens IDH1 protein protein. 268 1e-71
AF113917-1|AAD29284.1| 414|Homo sapiens NADP+-dependent isocitr... 268 1e-71
AF020038-1|AAD02918.1| 414|Homo sapiens NADP-dependent isocitra... 268 1e-71
AC016697-3|AAX93221.1| 414|Homo sapiens unknown protein. 268 1e-71
BX537411-1|CAD97653.1| 414|Homo sapiens hypothetical protein pr... 266 7e-71
CR533522-1|CAG38553.1| 414|Homo sapiens IDH1 protein. 264 2e-70
DQ403082-1|ABD77215.1| 371|Homo sapiens isocitrate dehydrogenas... 235 2e-61
U52144-1|AAC50455.1| 419|Homo sapiens isocitrate dehydrogenase ... 222 9e-58
U62389-1|AAB17375.1| 154|Homo sapiens putative cytosolic NADP-d... 120 5e-27
AK090454-1|BAC03435.1| 708|Homo sapiens FLJ00375 protein protein. 35 0.25
U25975-1|AAA75468.1| 493|Homo sapiens hPAK65 protein. 30 9.4
U24153-1|AAA65442.1| 525|Homo sapiens p21-activated protein kin... 30 9.4
BC069613-1|AAH69613.1| 524|Homo sapiens p21-activated kinase 2 ... 30 9.4
AB209428-1|BAD92665.1| 279|Homo sapiens p21-activated kinase 2 ... 30 9.4
>X69433-1|CAA49208.1| 452|Homo sapiens isocitrate dehydrogenase
(NADP+) protein.
Length = 452
Score = 279 bits (685), Expect = 5e-75
Identities = 129/188 (68%), Positives = 151/188 (80%), Gaps = 1/188 (0%)
Frame = +2
Query: 149 RNYGTAKRVVAAKPVVEMDGDEMTRIIWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQ 328
R + KR+ AKPVVEMDGDEMTRIIW IKE+LI P+V + YFDLGLP+RD TDDQ
Sbjct: 36 RRHYADKRIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQ 95
Query: 329 VTIDSAHAILKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQ 508
VTIDSA A K++V +KCATITPDE RVEEFKLKKMW SPNGTIRNILGGTVFREPI+C+
Sbjct: 96 VTIDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICK 155
Query: 509 SIPRVVPGWTKPIVIGRHAHGDQYKAQDFVVPKPGKVELVYTTQDGT-TERRVLYDFKTP 685
+IPR+VPGWTKPI IGRHAHGDQYKA DFV + G ++V+T +DG+ + +Y+F
Sbjct: 156 NIPRLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAG 215
Query: 686 GVAMGMYN 709
GV MGMYN
Sbjct: 216 GVGMGMYN 223
>BC071828-1|AAH71828.1| 452|Homo sapiens isocitrate dehydrogenase 2
(NADP+), mitochondrial protein.
Length = 452
Score = 279 bits (685), Expect = 5e-75
Identities = 129/188 (68%), Positives = 151/188 (80%), Gaps = 1/188 (0%)
Frame = +2
Query: 149 RNYGTAKRVVAAKPVVEMDGDEMTRIIWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQ 328
R + KR+ AKPVVEMDGDEMTRIIW IKE+LI P+V + YFDLGLP+RD TDDQ
Sbjct: 36 RRHYADKRIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQ 95
Query: 329 VTIDSAHAILKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQ 508
VTIDSA A K++V +KCATITPDE RVEEFKLKKMW SPNGTIRNILGGTVFREPI+C+
Sbjct: 96 VTIDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICK 155
Query: 509 SIPRVVPGWTKPIVIGRHAHGDQYKAQDFVVPKPGKVELVYTTQDGT-TERRVLYDFKTP 685
+IPR+VPGWTKPI IGRHAHGDQYKA DFV + G ++V+T +DG+ + +Y+F
Sbjct: 156 NIPRLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAG 215
Query: 686 GVAMGMYN 709
GV MGMYN
Sbjct: 216 GVGMGMYN 223
>BC009244-1|AAH09244.1| 452|Homo sapiens isocitrate dehydrogenase 2
(NADP+), mitochondrial protein.
Length = 452
Score = 279 bits (685), Expect = 5e-75
Identities = 129/188 (68%), Positives = 151/188 (80%), Gaps = 1/188 (0%)
Frame = +2
Query: 149 RNYGTAKRVVAAKPVVEMDGDEMTRIIWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQ 328
R + KR+ AKPVVEMDGDEMTRIIW IKE+LI P+V + YFDLGLP+RD TDDQ
Sbjct: 36 RRHYADKRIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQ 95
Query: 329 VTIDSAHAILKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQ 508
VTIDSA A K++V +KCATITPDE RVEEFKLKKMW SPNGTIRNILGGTVFREPI+C+
Sbjct: 96 VTIDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICK 155
Query: 509 SIPRVVPGWTKPIVIGRHAHGDQYKAQDFVVPKPGKVELVYTTQDGT-TERRVLYDFKTP 685
+IPR+VPGWTKPI IGRHAHGDQYKA DFV + G ++V+T +DG+ + +Y+F
Sbjct: 156 NIPRLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAG 215
Query: 686 GVAMGMYN 709
GV MGMYN
Sbjct: 216 GVGMGMYN 223
>AK222916-1|BAD96636.1| 452|Homo sapiens isocitrate dehydrogenase 2
(NADP+), mitochondrial precursor variant protein.
Length = 452
Score = 279 bits (685), Expect = 5e-75
Identities = 129/188 (68%), Positives = 151/188 (80%), Gaps = 1/188 (0%)
Frame = +2
Query: 149 RNYGTAKRVVAAKPVVEMDGDEMTRIIWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQ 328
R + KR+ AKPVVEMDGDEMTRIIW IKE+LI P+V + YFDLGLP+RD TDDQ
Sbjct: 36 RRHYADKRIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQ 95
Query: 329 VTIDSAHAILKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQ 508
VTIDSA A K++V +KCATITPDE RVEEFKLKKMW SPNGTIRNILGGTVFREPI+C+
Sbjct: 96 VTIDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICK 155
Query: 509 SIPRVVPGWTKPIVIGRHAHGDQYKAQDFVVPKPGKVELVYTTQDGT-TERRVLYDFKTP 685
+IPR+VPGWTKPI IGRHAHGDQYKA DFV + G ++V+T +DG+ + +Y+F
Sbjct: 156 NIPRLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAG 215
Query: 686 GVAMGMYN 709
GV MGMYN
Sbjct: 216 GVGMGMYN 223
>CR541695-1|CAG46496.1| 414|Homo sapiens IDH1 protein.
Length = 414
Score = 268 bits (657), Expect = 1e-71
Identities = 124/180 (68%), Positives = 151/180 (83%), Gaps = 2/180 (1%)
Frame = +2
Query: 176 VAAKPVVEMDGDEMTRIIWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQVTIDSAHAI 355
++ VVEM GDEMTRIIW IKE+LIFPYV++D +DLG+ +RDAT+DQVT D+A AI
Sbjct: 5 ISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAI 64
Query: 356 LKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQSIPRVVPGW 535
KHNVG+KCATITPDE+RVEEFKLK+MW SPNGTIRNILGGTVFRE I+C++IPR+V GW
Sbjct: 65 KKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGW 124
Query: 536 TKPIVIGRHAHGDQYKAQDFVVPKPGKVELVYTTQDGTTE-RRVLYDFKT-PGVAMGMYN 709
KPI+IGRHA+GDQY+A DFVVP PGKVE+ YT DGT + ++++F+ GVAMGMYN
Sbjct: 125 VKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYN 184
>CR536499-1|CAG38738.1| 414|Homo sapiens IDH1 protein.
Length = 414
Score = 268 bits (657), Expect = 1e-71
Identities = 124/180 (68%), Positives = 151/180 (83%), Gaps = 2/180 (1%)
Frame = +2
Query: 176 VAAKPVVEMDGDEMTRIIWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQVTIDSAHAI 355
++ VVEM GDEMTRIIW IKE+LIFPYV++D +DLG+ +RDAT+DQVT D+A AI
Sbjct: 5 ISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAI 64
Query: 356 LKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQSIPRVVPGW 535
KHNVG+KCATITPDE+RVEEFKLK+MW SPNGTIRNILGGTVFRE I+C++IPR+V GW
Sbjct: 65 KKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGW 124
Query: 536 TKPIVIGRHAHGDQYKAQDFVVPKPGKVELVYTTQDGTTE-RRVLYDFKT-PGVAMGMYN 709
KPI+IGRHA+GDQY+A DFVVP PGKVE+ YT DGT + ++++F+ GVAMGMYN
Sbjct: 125 VKPIIIGRHAYGDQYRATDFVVPGPGKVEMTYTPSDGTQKVTYLVHNFEEGGGVAMGMYN 184
>BC093020-1|AAH93020.1| 414|Homo sapiens isocitrate dehydrogenase 1
(NADP+), soluble protein.
Length = 414
Score = 268 bits (657), Expect = 1e-71
Identities = 124/180 (68%), Positives = 151/180 (83%), Gaps = 2/180 (1%)
Frame = +2
Query: 176 VAAKPVVEMDGDEMTRIIWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQVTIDSAHAI 355
++ VVEM GDEMTRIIW IKE+LIFPYV++D +DLG+ +RDAT+DQVT D+A AI
Sbjct: 5 ISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAI 64
Query: 356 LKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQSIPRVVPGW 535
KHNVG+KCATITPDE+RVEEFKLK+MW SPNGTIRNILGGTVFRE I+C++IPR+V GW
Sbjct: 65 KKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGW 124
Query: 536 TKPIVIGRHAHGDQYKAQDFVVPKPGKVELVYTTQDGTTE-RRVLYDFKT-PGVAMGMYN 709
KPI+IGRHA+GDQY+A DFVVP PGKVE+ YT DGT + ++++F+ GVAMGMYN
Sbjct: 125 VKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYN 184
>BC012846-1|AAH12846.1| 414|Homo sapiens IDH1 protein protein.
Length = 414
Score = 268 bits (657), Expect = 1e-71
Identities = 124/180 (68%), Positives = 151/180 (83%), Gaps = 2/180 (1%)
Frame = +2
Query: 176 VAAKPVVEMDGDEMTRIIWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQVTIDSAHAI 355
++ VVEM GDEMTRIIW IKE+LIFPYV++D +DLG+ +RDAT+DQVT D+A AI
Sbjct: 5 ISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAI 64
Query: 356 LKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQSIPRVVPGW 535
KHNVG+KCATITPDE+RVEEFKLK+MW SPNGTIRNILGGTVFRE I+C++IPR+V GW
Sbjct: 65 KKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGW 124
Query: 536 TKPIVIGRHAHGDQYKAQDFVVPKPGKVELVYTTQDGTTE-RRVLYDFKT-PGVAMGMYN 709
KPI+IGRHA+GDQY+A DFVVP PGKVE+ YT DGT + ++++F+ GVAMGMYN
Sbjct: 125 VKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYN 184
>AF113917-1|AAD29284.1| 414|Homo sapiens NADP+-dependent isocitrate
dehydrogenase protein.
Length = 414
Score = 268 bits (657), Expect = 1e-71
Identities = 124/180 (68%), Positives = 151/180 (83%), Gaps = 2/180 (1%)
Frame = +2
Query: 176 VAAKPVVEMDGDEMTRIIWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQVTIDSAHAI 355
++ VVEM GDEMTRIIW IKE+LIFPYV++D +DLG+ +RDAT+DQVT D+A AI
Sbjct: 5 ISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAI 64
Query: 356 LKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQSIPRVVPGW 535
KHNVG+KCATITPDE+RVEEFKLK+MW SPNGTIRNILGGTVFRE I+C++IPR+V GW
Sbjct: 65 KKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGW 124
Query: 536 TKPIVIGRHAHGDQYKAQDFVVPKPGKVELVYTTQDGTTE-RRVLYDFKT-PGVAMGMYN 709
KPI+IGRHA+GDQY+A DFVVP PGKVE+ YT DGT + ++++F+ GVAMGMYN
Sbjct: 125 VKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYN 184
>AF020038-1|AAD02918.1| 414|Homo sapiens NADP-dependent isocitrate
dehydrogenase protein.
Length = 414
Score = 268 bits (657), Expect = 1e-71
Identities = 124/180 (68%), Positives = 151/180 (83%), Gaps = 2/180 (1%)
Frame = +2
Query: 176 VAAKPVVEMDGDEMTRIIWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQVTIDSAHAI 355
++ VVEM GDEMTRIIW IKE+LIFPYV++D +DLG+ +RDAT+DQVT D+A AI
Sbjct: 5 ISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAI 64
Query: 356 LKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQSIPRVVPGW 535
KHNVG+KCATITPDE+RVEEFKLK+MW SPNGTIRNILGGTVFRE I+C++IPR+V GW
Sbjct: 65 KKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGW 124
Query: 536 TKPIVIGRHAHGDQYKAQDFVVPKPGKVELVYTTQDGTTE-RRVLYDFKT-PGVAMGMYN 709
KPI+IGRHA+GDQY+A DFVVP PGKVE+ YT DGT + ++++F+ GVAMGMYN
Sbjct: 125 VKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYN 184
>AC016697-3|AAX93221.1| 414|Homo sapiens unknown protein.
Length = 414
Score = 268 bits (657), Expect = 1e-71
Identities = 124/180 (68%), Positives = 151/180 (83%), Gaps = 2/180 (1%)
Frame = +2
Query: 176 VAAKPVVEMDGDEMTRIIWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQVTIDSAHAI 355
++ VVEM GDEMTRIIW IKE+LIFPYV++D +DLG+ +RDAT+DQVT D+A AI
Sbjct: 5 ISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAI 64
Query: 356 LKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQSIPRVVPGW 535
KHNVG+KCATITPDE+RVEEFKLK+MW SPNGTIRNILGGTVFRE I+C++IPR+V GW
Sbjct: 65 KKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGW 124
Query: 536 TKPIVIGRHAHGDQYKAQDFVVPKPGKVELVYTTQDGTTE-RRVLYDFKT-PGVAMGMYN 709
KPI+IGRHA+GDQY+A DFVVP PGKVE+ YT DGT + ++++F+ GVAMGMYN
Sbjct: 125 VKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYN 184
>BX537411-1|CAD97653.1| 414|Homo sapiens hypothetical protein
protein.
Length = 414
Score = 266 bits (651), Expect = 7e-71
Identities = 124/180 (68%), Positives = 146/180 (81%), Gaps = 2/180 (1%)
Frame = +2
Query: 176 VAAKPVVEMDGDEMTRIIWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQVTIDSAHAI 355
++ VVEM GDEMTRIIW IKE+LIFPYV++D +DLG+ +RDAT+DQVT D+A AI
Sbjct: 5 ISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAI 64
Query: 356 LKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQSIPRVVPGW 535
KHNVG+KCATITPDE+RVEEFKLK+MW SPNGTIRNILGGTVFRE I+C++IPR+V GW
Sbjct: 65 KKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGW 124
Query: 536 TKPIVIGRHAHGDQYKAQDFVVPKPGKVELVYTTQDGTTERRVLYDFKT--PGVAMGMYN 709
KPI+IGRHA+GDQY+A DFVVP PGKVE+ YT DGT + L GVAMGMYN
Sbjct: 125 VKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNSEGGGGVAMGMYN 184
>CR533522-1|CAG38553.1| 414|Homo sapiens IDH1 protein.
Length = 414
Score = 264 bits (647), Expect = 2e-70
Identities = 122/180 (67%), Positives = 150/180 (83%), Gaps = 2/180 (1%)
Frame = +2
Query: 176 VAAKPVVEMDGDEMTRIIWAKIKERLIFPYVKVDCLYFDLGLPHRDATDDQVTIDSAHAI 355
++ VVEM GDEMTRIIW IKE+LI PYV++D +DLG+ +RDAT+DQVT D+A AI
Sbjct: 5 ISGGSVVEMQGDEMTRIIWELIKEKLIIPYVELDLHSYDLGIENRDATNDQVTKDAAEAI 64
Query: 356 LKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTVFREPILCQSIPRVVPGW 535
KHNVG+KCATITPDE+RVEEFKLK+MW SPNGTIRNILGGTVFRE I+C++IPR+V GW
Sbjct: 65 KKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGW 124
Query: 536 TKPIVIGRHAHGDQYKAQDFVVPKPGKVELVYTTQDGTTE-RRVLYDFKT-PGVAMGMYN 709
+PI+IGRHA+GDQY+A DFVVP PGKVE+ YT DGT + ++++F+ GVAMGMYN
Sbjct: 125 VEPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYN 184
>DQ403082-1|ABD77215.1| 371|Homo sapiens isocitrate dehydrogenase 1
protein.
Length = 371
Score = 235 bits (574), Expect = 2e-61
Identities = 108/155 (69%), Positives = 132/155 (85%), Gaps = 2/155 (1%)
Frame = +2
Query: 251 LIFPYVKVDCLYFDLGLPHRDATDDQVTIDSAHAILKHNVGIKCATITPDEQRVEEFKLK 430
LIFPYV++D +DLG+ +RDAT+DQVT D+A AI KHNVG+KCATITPDE+RVEEFKLK
Sbjct: 1 LIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFKLK 60
Query: 431 KMWLSPNGTIRNILGGTVFREPILCQSIPRVVPGWTKPIVIGRHAHGDQYKAQDFVVPKP 610
+MW SPNGTIRNILGGTVFRE I+C++IPR+V GW KPI+IGRHA+GDQY+A DFVVP P
Sbjct: 61 QMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGP 120
Query: 611 GKVELVYTTQDGTTE-RRVLYDFKT-PGVAMGMYN 709
GKVE+ YT DGT + ++++F+ GVAMGMYN
Sbjct: 121 GKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYN 155
>U52144-1|AAC50455.1| 419|Homo sapiens isocitrate dehydrogenase
protein.
Length = 419
Score = 222 bits (543), Expect = 9e-58
Identities = 102/147 (69%), Positives = 119/147 (80%), Gaps = 1/147 (0%)
Frame = +2
Query: 272 VDCLYFDLGLPHRDATDDQVTIDSAHAILKHNVGIKCATITPDEQRVEEFKLKKMWLSPN 451
V YFDLGLP+RD TDDQVTIDSA A K++V +KCATITPDE RVEEFKLKKMW SPN
Sbjct: 44 VQLKYFDLGLPNRDQTDDQVTIDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPN 103
Query: 452 GTIRNILGGTVFREPILCQSIPRVVPGWTKPIVIGRHAHGDQYKAQDFVVPKPGKVELVY 631
GTIRNI GGTVFREPI+C++IPR+VPGWTKPI IGRHAHGDQYKA DFV + G ++V+
Sbjct: 104 GTIRNIHGGTVFREPIICKNIPRLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVF 163
Query: 632 TTQDGT-TERRVLYDFKTPGVAMGMYN 709
T +DG+ + +Y+F GV MGMYN
Sbjct: 164 TPKDGSGVKEWEVYNFPAGGVGMGMYN 190
>U62389-1|AAB17375.1| 154|Homo sapiens putative cytosolic
NADP-dependent isocitrate dehydrogenase protein.
Length = 154
Score = 120 bits (289), Expect = 5e-27
Identities = 55/85 (64%), Positives = 69/85 (81%), Gaps = 2/85 (2%)
Frame = +2
Query: 461 RNILGGTVFREPILCQSIPRVVPGWTKPIVIGRHAHGDQYKAQDFVVPKPGKVELVYTTQ 640
RNILGGTVF E I+C++IPR+V GW KPI+IGRHA+GDQY+A DFVVP PGKVE+ YT
Sbjct: 1 RNILGGTVFXEAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPS 60
Query: 641 DGTTE-RRVLYDFKT-PGVAMGMYN 709
DGT + ++++F+ GVAMGMYN
Sbjct: 61 DGTQKVTYLVHNFEEGGGVAMGMYN 85
>AK090454-1|BAC03435.1| 708|Homo sapiens FLJ00375 protein protein.
Length = 708
Score = 35.1 bits (77), Expect = 0.25
Identities = 15/43 (34%), Positives = 21/43 (48%)
Frame = +2
Query: 515 PRVVPGWTKPIVIGRHAHGDQYKAQDFVVPKPGKVELVYTTQD 643
PR GW +P + H H DQ +P PGK +L+ +D
Sbjct: 20 PRAFKGWARPWLAQCHLHADQQPRAMHRMPDPGKFKLLEQARD 62
>U25975-1|AAA75468.1| 493|Homo sapiens hPAK65 protein.
Length = 493
Score = 29.9 bits (64), Expect = 9.4
Identities = 16/60 (26%), Positives = 25/60 (41%)
Frame = +2
Query: 305 HRDATDDQVTIDSAHAILKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTV 484
HRD D V + ++ + G CA ITP++ + W++P R G V
Sbjct: 335 HRDIKSDNVLLGMEGSVKLTDFGF-CAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKV 393
>U24153-1|AAA65442.1| 525|Homo sapiens p21-activated protein kinase
protein.
Length = 525
Score = 29.9 bits (64), Expect = 9.4
Identities = 16/60 (26%), Positives = 25/60 (41%)
Frame = +2
Query: 305 HRDATDDQVTIDSAHAILKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTV 484
HRD D V + ++ + G CA ITP++ + W++P R G V
Sbjct: 367 HRDIKSDNVLLGMEGSVKLTDFGF-CAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKV 425
>BC069613-1|AAH69613.1| 524|Homo sapiens p21-activated kinase 2
protein.
Length = 524
Score = 29.9 bits (64), Expect = 9.4
Identities = 16/60 (26%), Positives = 25/60 (41%)
Frame = +2
Query: 305 HRDATDDQVTIDSAHAILKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTV 484
HRD D V + ++ + G CA ITP++ + W++P R G V
Sbjct: 366 HRDIKSDNVLLGMEGSVKLTDFGF-CAQITPEQSKRSTMVGTPYWMAPEVVTRKAYGPKV 424
>AB209428-1|BAD92665.1| 279|Homo sapiens p21-activated kinase 2
variant protein.
Length = 279
Score = 29.9 bits (64), Expect = 9.4
Identities = 16/60 (26%), Positives = 25/60 (41%)
Frame = +2
Query: 305 HRDATDDQVTIDSAHAILKHNVGIKCATITPDEQRVEEFKLKKMWLSPNGTIRNILGGTV 484
HRD D V + ++ + G CA ITP++ + W++P R G V
Sbjct: 124 HRDIKSDSVLLGMEGSVKLTDFGF-CAQITPEQSKRSTVIRTPYWMAPEVVTRKAYGPKV 182
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 106,305,694
Number of Sequences: 237096
Number of extensions: 2238949
Number of successful extensions: 4507
Number of sequences better than 10.0: 21
Number of HSP's better than 10.0 without gapping: 4397
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4491
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8287202872
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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