Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= bmmt2k14
(755 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AL583862-8|CAI14893.1| 247|Homo sapiens hydroxypyruvate isomera... 175 1e-43
AY775560-1|AAV84474.1| 229|Homo sapiens endothelial cell apopto... 164 4e-40
BC019041-1|AAH19041.1| 174|Homo sapiens HYI protein protein. 122 1e-27
BC006140-1|AAH06140.1| 217|Homo sapiens HYI protein protein. 122 1e-27
AL583862-5|CAI14890.1| 204|Homo sapiens hydroxypyruvate isomera... 122 1e-27
AF284751-1|AAG59853.1| 174|Homo sapiens HT036 protein. 122 1e-27
AF284750-1|AAG59852.1| 204|Homo sapiens HT036-ISO protein. 122 1e-27
AL583862-7|CAI14892.1| 165|Homo sapiens hydroxypyruvate isomera... 103 9e-22
AL583862-4|CAI14889.1| 180|Homo sapiens hydroxypyruvate isomera... 99 2e-20
AL583862-6|CAI14891.1| 229|Homo sapiens hydroxypyruvate isomera... 98 3e-20
>AL583862-8|CAI14893.1| 247|Homo sapiens hydroxypyruvate isomerase
homolog (E. coli) protein.
Length = 247
Score = 175 bits (427), Expect = 1e-43
Identities = 91/219 (41%), Positives = 137/219 (62%), Gaps = 7/219 (3%)
Frame = +1
Query: 115 MKFCANLSFMFAEASSILERYALAKDAGFKAVESGFPFGFSLEQVRNAKQSAGLQQIAIN 294
++F ANLS++F E S + R A +GF+AVE +P+ + E + A + AGL+ + IN
Sbjct: 4 LRFSANLSWLFPELSGLPARVRAAGSSGFEAVEVAWPYAETPEALARAAREAGLRLVLIN 63
Query: 295 LKTGDTTKGEVGVTSVPGKEDEFKTNLNTTIEYAKALDAKKIHIMAGKVENPTPK----- 459
GD KGE+G+ +VPG++ F+ L + YAKAL +IH+MAG+V +
Sbjct: 64 TPPGDQEKGEMGLGAVPGRQAAFREGLEQAVRYAKALGCPRIHLMAGRVPQGADRIAVKA 123
Query: 460 HWE-TFEKNLLYAVDVLKGENIQGLIEPIN-QYSMPKYFLSDYGRAVDIIKRIDSPNLRL 633
E F +NL +A VL E++ GL+EPIN + + P+YFL +A I++++ PNL+L
Sbjct: 124 EMEAVFLENLRHAAGVLAQEDLVGLLEPINTRITDPQYFLDTPQQAAAILQKVGRPNLQL 183
Query: 634 MLDIFHLQQIAGDITHNITKLLPYIGHVQIAQVPNRNEP 750
+DIFH Q + G++T NI + LP +GHVQ+AQVP R EP
Sbjct: 184 QMDIFHWQIMDGNLTGNIREFLPIVGHVQVAQVPGRGEP 222
>AY775560-1|AAV84474.1| 229|Homo sapiens endothelial cell apoptosis
protein E-CE1 protein.
Length = 229
Score = 164 bits (398), Expect = 4e-40
Identities = 86/214 (40%), Positives = 132/214 (61%), Gaps = 7/214 (3%)
Frame = +1
Query: 115 MKFCANLSFMFAEASSILERYALAKDAGFKAVESGFPFGFSLEQVRNAKQSAGLQQIAIN 294
++F ANLS++F E + R A +GF+AVE +P+ + E + A + AGL+ + IN
Sbjct: 4 LRFSANLSWLFPELPGLPARVRAAGSSGFEAVEVAWPYAETPEALARAAREAGLRLVLIN 63
Query: 295 LKTGDTTKGEVGVTSVPGKEDEFKTNLNTTIEYAKALDAKKIHIMAGKVENPTPK----- 459
GD KGE+G+ +VPG++ F+ L + YAKAL +IH+MAG+V +
Sbjct: 64 TPPGDQEKGEMGLGAVPGRQAAFREGLEQAVRYAKALGCPRIHLMAGRVPQGADRIAVKA 123
Query: 460 HWE-TFEKNLLYAVDVLKGENIQGLIEPIN-QYSMPKYFLSDYGRAVDIIKRIDSPNLRL 633
E F +NL +A VL E++ GL+EPIN + + P+YFL +A I++++ PNL+L
Sbjct: 124 EMEAVFLENLRHAAGVLAQEDLVGLLEPINTRITDPQYFLDTPQQAAAILQKVGRPNLQL 183
Query: 634 MLDIFHLQQIAGDITHNITKLLPYIGHVQIAQVP 735
+DIFH Q + G++T NI + LP +GHVQ+AQ P
Sbjct: 184 QMDIFHWQIMDGNLTGNIREFLPIVGHVQVAQGP 217
>BC019041-1|AAH19041.1| 174|Homo sapiens HYI protein protein.
Length = 174
Score = 122 bits (295), Expect = 1e-27
Identities = 63/149 (42%), Positives = 95/149 (63%), Gaps = 7/149 (4%)
Frame = +1
Query: 325 VGVTSVPGKEDEFKTNLNTTIEYAKALDAKKIHIMAGKVENPTPK-----HWET-FEKNL 486
+G+ +VPG++ F+ L + YAKAL +IH+MAG+V + E F +NL
Sbjct: 1 MGLGAVPGRQAAFREGLEQAVRYAKALGCPRIHLMAGRVPQGADRIAVKAEMEAVFLENL 60
Query: 487 LYAVDVLKGENIQGLIEPIN-QYSMPKYFLSDYGRAVDIIKRIDSPNLRLMLDIFHLQQI 663
+A VL E++ GL+EPIN + + P+YFL +A I++++ PNL+L +DIFH Q +
Sbjct: 61 RHAAGVLAQEDLVGLLEPINTRITDPQYFLDTPQQAAAILQKVGRPNLQLQMDIFHWQIM 120
Query: 664 AGDITHNITKLLPYIGHVQIAQVPNRNEP 750
G++T NI + LP +GHVQ+AQVP R EP
Sbjct: 121 DGNLTGNIREFLPIVGHVQVAQVPGRGEP 149
>BC006140-1|AAH06140.1| 217|Homo sapiens HYI protein protein.
Length = 217
Score = 122 bits (295), Expect = 1e-27
Identities = 63/149 (42%), Positives = 95/149 (63%), Gaps = 7/149 (4%)
Frame = +1
Query: 325 VGVTSVPGKEDEFKTNLNTTIEYAKALDAKKIHIMAGKVENPTPK-----HWET-FEKNL 486
+G+ +VPG++ F+ L + YAKAL +IH+MAG+V + E F +NL
Sbjct: 1 MGLGAVPGRQAAFREGLEQAVRYAKALGCPRIHLMAGRVPQGADRIAVKAEMEAVFLENL 60
Query: 487 LYAVDVLKGENIQGLIEPIN-QYSMPKYFLSDYGRAVDIIKRIDSPNLRLMLDIFHLQQI 663
+A VL E++ GL+EPIN + + P+YFL +A I++++ PNL+L +DIFH Q +
Sbjct: 61 RHAAGVLAQEDLVGLLEPINTRITDPQYFLDTPQQAAAILQKVGRPNLQLQMDIFHWQIM 120
Query: 664 AGDITHNITKLLPYIGHVQIAQVPNRNEP 750
G++T NI + LP +GHVQ+AQVP R EP
Sbjct: 121 DGNLTGNIREFLPIVGHVQVAQVPGRGEP 149
>AL583862-5|CAI14890.1| 204|Homo sapiens hydroxypyruvate isomerase
homolog (E. coli) protein.
Length = 204
Score = 122 bits (295), Expect = 1e-27
Identities = 63/149 (42%), Positives = 95/149 (63%), Gaps = 7/149 (4%)
Frame = +1
Query: 325 VGVTSVPGKEDEFKTNLNTTIEYAKALDAKKIHIMAGKVENPTPK-----HWET-FEKNL 486
+G+ +VPG++ F+ L + YAKAL +IH+MAG+V + E F +NL
Sbjct: 1 MGLGAVPGRQAAFREGLEQAVRYAKALGCPRIHLMAGRVPQGADRIAVKAEMEAVFLENL 60
Query: 487 LYAVDVLKGENIQGLIEPIN-QYSMPKYFLSDYGRAVDIIKRIDSPNLRLMLDIFHLQQI 663
+A VL E++ GL+EPIN + + P+YFL +A I++++ PNL+L +DIFH Q +
Sbjct: 61 RHAAGVLAQEDLVGLLEPINTRITDPQYFLDTPQQAAAILQKVGRPNLQLQMDIFHWQIM 120
Query: 664 AGDITHNITKLLPYIGHVQIAQVPNRNEP 750
G++T NI + LP +GHVQ+AQVP R EP
Sbjct: 121 DGNLTGNIREFLPIVGHVQVAQVPGRGEP 149
>AF284751-1|AAG59853.1| 174|Homo sapiens HT036 protein.
Length = 174
Score = 122 bits (295), Expect = 1e-27
Identities = 63/149 (42%), Positives = 95/149 (63%), Gaps = 7/149 (4%)
Frame = +1
Query: 325 VGVTSVPGKEDEFKTNLNTTIEYAKALDAKKIHIMAGKVENPTPK-----HWET-FEKNL 486
+G+ +VPG++ F+ L + YAKAL +IH+MAG+V + E F +NL
Sbjct: 1 MGLGAVPGRQAAFREGLEQAVRYAKALGCPRIHLMAGRVPQGADRIAVKAEMEAVFLENL 60
Query: 487 LYAVDVLKGENIQGLIEPIN-QYSMPKYFLSDYGRAVDIIKRIDSPNLRLMLDIFHLQQI 663
+A VL E++ GL+EPIN + + P+YFL +A I++++ PNL+L +DIFH Q +
Sbjct: 61 RHAAGVLAQEDLVGLLEPINTRITDPQYFLDTPQQAAAILQKVGRPNLQLQMDIFHWQIM 120
Query: 664 AGDITHNITKLLPYIGHVQIAQVPNRNEP 750
G++T NI + LP +GHVQ+AQVP R EP
Sbjct: 121 DGNLTGNIREFLPIVGHVQVAQVPGRGEP 149
>AF284750-1|AAG59852.1| 204|Homo sapiens HT036-ISO protein.
Length = 204
Score = 122 bits (295), Expect = 1e-27
Identities = 63/149 (42%), Positives = 95/149 (63%), Gaps = 7/149 (4%)
Frame = +1
Query: 325 VGVTSVPGKEDEFKTNLNTTIEYAKALDAKKIHIMAGKVENPTPK-----HWET-FEKNL 486
+G+ +VPG++ F+ L + YAKAL +IH+MAG+V + E F +NL
Sbjct: 1 MGLGAVPGRQAAFREGLEQAVRYAKALGCPRIHLMAGRVPQGADRIAVKAEMEAVFLENL 60
Query: 487 LYAVDVLKGENIQGLIEPIN-QYSMPKYFLSDYGRAVDIIKRIDSPNLRLMLDIFHLQQI 663
+A VL E++ GL+EPIN + + P+YFL +A I++++ PNL+L +DIFH Q +
Sbjct: 61 RHAAGVLAQEDLVGLLEPINTRITDPQYFLDTPQQAAAILQKVGRPNLQLQMDIFHWQIM 120
Query: 664 AGDITHNITKLLPYIGHVQIAQVPNRNEP 750
G++T NI + LP +GHVQ+AQVP R EP
Sbjct: 121 DGNLTGNIREFLPIVGHVQVAQVPGRGEP 149
>AL583862-7|CAI14892.1| 165|Homo sapiens hydroxypyruvate isomerase
homolog (E. coli) protein.
Length = 165
Score = 103 bits (246), Expect = 9e-22
Identities = 58/149 (38%), Positives = 90/149 (60%), Gaps = 7/149 (4%)
Frame = +1
Query: 325 VGVTSVPGKEDEFKTNLNTTIEYAKALDAKKIHIMAGKVENPTPK-----HWET-FEKNL 486
+G+ +VPG++ F+ L + +IH+MAG+V + E F +NL
Sbjct: 1 MGLGAVPGRQAAFREGLEQAV---------RIHLMAGRVPQGADRIAVKAEMEAVFLENL 51
Query: 487 LYAVDVLKGENIQGLIEPIN-QYSMPKYFLSDYGRAVDIIKRIDSPNLRLMLDIFHLQQI 663
+A VL E++ GL+EPIN + + P+YFL +A I++++ PNL+L +DIFH Q +
Sbjct: 52 RHAAGVLAQEDLVGLLEPINTRITDPQYFLDTPQQAAAILQKVGRPNLQLQMDIFHWQIM 111
Query: 664 AGDITHNITKLLPYIGHVQIAQVPNRNEP 750
G++T NI + LP +GHVQ+AQVP R EP
Sbjct: 112 DGNLTGNIREFLPIVGHVQVAQVPGRGEP 140
>AL583862-4|CAI14889.1| 180|Homo sapiens hydroxypyruvate isomerase
homolog (E. coli) protein.
Length = 180
Score = 98.7 bits (235), Expect = 2e-20
Identities = 52/119 (43%), Positives = 77/119 (64%), Gaps = 7/119 (5%)
Frame = +1
Query: 415 KIHIMAGKVENPTPK-----HWET-FEKNLLYAVDVLKGENIQGLIEPIN-QYSMPKYFL 573
+IH+MAG+V + E F +NL +A VL E++ GL+EPIN + + P+YFL
Sbjct: 37 RIHLMAGRVPQGADRIAVKAEMEAVFLENLRHAAGVLAQEDLVGLLEPINTRITDPQYFL 96
Query: 574 SDYGRAVDIIKRIDSPNLRLMLDIFHLQQIAGDITHNITKLLPYIGHVQIAQVPNRNEP 750
+A I++++ PNL+L +DIFH Q + G++T NI + LP +GHVQ+AQVP R EP
Sbjct: 97 DTPQQAAAILQKVGRPNLQLQMDIFHWQIMDGNLTGNIREFLPIVGHVQVAQVPGRGEP 155
>AL583862-6|CAI14891.1| 229|Homo sapiens hydroxypyruvate isomerase
homolog (E. coli) protein.
Length = 229
Score = 97.9 bits (233), Expect = 3e-20
Identities = 52/118 (44%), Positives = 76/118 (64%), Gaps = 7/118 (5%)
Frame = +1
Query: 418 IHIMAGKVENPTPK-----HWET-FEKNLLYAVDVLKGENIQGLIEPIN-QYSMPKYFLS 576
IH+MAG+V + E F +NL +A VL E++ GL+EPIN + + P+YFL
Sbjct: 57 IHLMAGRVPQGADRIAVKAEMEAVFLENLRHAAGVLAQEDLVGLLEPINTRITDPQYFLD 116
Query: 577 DYGRAVDIIKRIDSPNLRLMLDIFHLQQIAGDITHNITKLLPYIGHVQIAQVPNRNEP 750
+A I++++ PNL+L +DIFH Q + G++T NI + LP +GHVQ+AQVP R EP
Sbjct: 117 TPQQAAAILQKVGRPNLQLQMDIFHWQIMDGNLTGNIREFLPIVGHVQVAQVPGRGEP 174
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 100,351,160
Number of Sequences: 237096
Number of extensions: 2058256
Number of successful extensions: 4009
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3808
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3987
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 9127122082
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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