Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= bmmt2j22
(725 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
CR541695-1|CAG46496.1| 414|Homo sapiens IDH1 protein. 309 8e-84
BC093020-1|AAH93020.1| 414|Homo sapiens isocitrate dehydrogenas... 309 8e-84
BC012846-1|AAH12846.1| 414|Homo sapiens IDH1 protein protein. 309 8e-84
AF113917-1|AAD29284.1| 414|Homo sapiens NADP+-dependent isocitr... 309 8e-84
AF020038-1|AAD02918.1| 414|Homo sapiens NADP-dependent isocitra... 309 8e-84
AC016697-3|AAX93221.1| 414|Homo sapiens unknown protein. 309 8e-84
CR533522-1|CAG38553.1| 414|Homo sapiens IDH1 protein. 308 1e-83
CR536499-1|CAG38738.1| 414|Homo sapiens IDH1 protein. 308 2e-83
BX537411-1|CAD97653.1| 414|Homo sapiens hypothetical protein pr... 307 3e-83
X69433-1|CAA49208.1| 452|Homo sapiens isocitrate dehydrogenase... 289 5e-78
BC071828-1|AAH71828.1| 452|Homo sapiens isocitrate dehydrogenas... 289 7e-78
BC009244-1|AAH09244.1| 452|Homo sapiens isocitrate dehydrogenas... 289 7e-78
AK222916-1|BAD96636.1| 452|Homo sapiens isocitrate dehydrogenas... 289 7e-78
DQ403082-1|ABD77215.1| 371|Homo sapiens isocitrate dehydrogenas... 269 8e-72
U52144-1|AAC50455.1| 419|Homo sapiens isocitrate dehydrogenase ... 242 8e-64
U62389-1|AAB17375.1| 154|Homo sapiens putative cytosolic NADP-d... 144 4e-34
AK090454-1|BAC03435.1| 708|Homo sapiens FLJ00375 protein protein. 32 1.8
BC020198-1|AAH20198.1| 567|Homo sapiens MEGF10 protein protein. 30 7.3
AB058676-1|BAB47409.1| 1140|Homo sapiens MEGF10 protein (KIAA178... 30 7.3
>CR541695-1|CAG46496.1| 414|Homo sapiens IDH1 protein.
Length = 414
Score = 309 bits (758), Expect = 8e-84
Identities = 143/206 (69%), Positives = 172/206 (83%), Gaps = 2/206 (0%)
Frame = +1
Query: 109 KIKAGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTIDCAEA 288
KI G VV++ GDEMTRIIW+LIKEKLI P+++++LH YDLG+ENRD T+DQVT D AEA
Sbjct: 4 KISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEA 63
Query: 289 IKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTG 468
IKK+NVG+KCATITPDEKRVEEFKLK+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+G
Sbjct: 64 IKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSG 123
Query: 469 WDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESG-EAIKHVVHEY-KGAGVALAMF 642
W KPIIIGRHA+ DQY+ATDFVVPG G +EI + P G + + ++VH + +G GVA+ M+
Sbjct: 124 WVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMY 183
Query: 643 NTDASIIDFAHSSFKVXFGQKIPSVL 720
N D SI DFAHSSF++ + P L
Sbjct: 184 NQDKSIEDFAHSSFQMALSKGWPLYL 209
>BC093020-1|AAH93020.1| 414|Homo sapiens isocitrate dehydrogenase 1
(NADP+), soluble protein.
Length = 414
Score = 309 bits (758), Expect = 8e-84
Identities = 143/206 (69%), Positives = 172/206 (83%), Gaps = 2/206 (0%)
Frame = +1
Query: 109 KIKAGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTIDCAEA 288
KI G VV++ GDEMTRIIW+LIKEKLI P+++++LH YDLG+ENRD T+DQVT D AEA
Sbjct: 4 KISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEA 63
Query: 289 IKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTG 468
IKK+NVG+KCATITPDEKRVEEFKLK+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+G
Sbjct: 64 IKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSG 123
Query: 469 WDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESG-EAIKHVVHEY-KGAGVALAMF 642
W KPIIIGRHA+ DQY+ATDFVVPG G +EI + P G + + ++VH + +G GVA+ M+
Sbjct: 124 WVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMY 183
Query: 643 NTDASIIDFAHSSFKVXFGQKIPSVL 720
N D SI DFAHSSF++ + P L
Sbjct: 184 NQDKSIEDFAHSSFQMALSKGWPLYL 209
>BC012846-1|AAH12846.1| 414|Homo sapiens IDH1 protein protein.
Length = 414
Score = 309 bits (758), Expect = 8e-84
Identities = 143/206 (69%), Positives = 172/206 (83%), Gaps = 2/206 (0%)
Frame = +1
Query: 109 KIKAGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTIDCAEA 288
KI G VV++ GDEMTRIIW+LIKEKLI P+++++LH YDLG+ENRD T+DQVT D AEA
Sbjct: 4 KISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEA 63
Query: 289 IKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTG 468
IKK+NVG+KCATITPDEKRVEEFKLK+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+G
Sbjct: 64 IKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSG 123
Query: 469 WDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESG-EAIKHVVHEY-KGAGVALAMF 642
W KPIIIGRHA+ DQY+ATDFVVPG G +EI + P G + + ++VH + +G GVA+ M+
Sbjct: 124 WVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMY 183
Query: 643 NTDASIIDFAHSSFKVXFGQKIPSVL 720
N D SI DFAHSSF++ + P L
Sbjct: 184 NQDKSIEDFAHSSFQMALSKGWPLYL 209
>AF113917-1|AAD29284.1| 414|Homo sapiens NADP+-dependent isocitrate
dehydrogenase protein.
Length = 414
Score = 309 bits (758), Expect = 8e-84
Identities = 143/206 (69%), Positives = 172/206 (83%), Gaps = 2/206 (0%)
Frame = +1
Query: 109 KIKAGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTIDCAEA 288
KI G VV++ GDEMTRIIW+LIKEKLI P+++++LH YDLG+ENRD T+DQVT D AEA
Sbjct: 4 KISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEA 63
Query: 289 IKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTG 468
IKK+NVG+KCATITPDEKRVEEFKLK+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+G
Sbjct: 64 IKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSG 123
Query: 469 WDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESG-EAIKHVVHEY-KGAGVALAMF 642
W KPIIIGRHA+ DQY+ATDFVVPG G +EI + P G + + ++VH + +G GVA+ M+
Sbjct: 124 WVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMY 183
Query: 643 NTDASIIDFAHSSFKVXFGQKIPSVL 720
N D SI DFAHSSF++ + P L
Sbjct: 184 NQDKSIEDFAHSSFQMALSKGWPLYL 209
>AF020038-1|AAD02918.1| 414|Homo sapiens NADP-dependent isocitrate
dehydrogenase protein.
Length = 414
Score = 309 bits (758), Expect = 8e-84
Identities = 143/206 (69%), Positives = 172/206 (83%), Gaps = 2/206 (0%)
Frame = +1
Query: 109 KIKAGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTIDCAEA 288
KI G VV++ GDEMTRIIW+LIKEKLI P+++++LH YDLG+ENRD T+DQVT D AEA
Sbjct: 4 KISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEA 63
Query: 289 IKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTG 468
IKK+NVG+KCATITPDEKRVEEFKLK+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+G
Sbjct: 64 IKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSG 123
Query: 469 WDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESG-EAIKHVVHEY-KGAGVALAMF 642
W KPIIIGRHA+ DQY+ATDFVVPG G +EI + P G + + ++VH + +G GVA+ M+
Sbjct: 124 WVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMY 183
Query: 643 NTDASIIDFAHSSFKVXFGQKIPSVL 720
N D SI DFAHSSF++ + P L
Sbjct: 184 NQDKSIEDFAHSSFQMALSKGWPLYL 209
>AC016697-3|AAX93221.1| 414|Homo sapiens unknown protein.
Length = 414
Score = 309 bits (758), Expect = 8e-84
Identities = 143/206 (69%), Positives = 172/206 (83%), Gaps = 2/206 (0%)
Frame = +1
Query: 109 KIKAGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTIDCAEA 288
KI G VV++ GDEMTRIIW+LIKEKLI P+++++LH YDLG+ENRD T+DQVT D AEA
Sbjct: 4 KISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEA 63
Query: 289 IKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTG 468
IKK+NVG+KCATITPDEKRVEEFKLK+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+G
Sbjct: 64 IKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSG 123
Query: 469 WDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESG-EAIKHVVHEY-KGAGVALAMF 642
W KPIIIGRHA+ DQY+ATDFVVPG G +EI + P G + + ++VH + +G GVA+ M+
Sbjct: 124 WVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMY 183
Query: 643 NTDASIIDFAHSSFKVXFGQKIPSVL 720
N D SI DFAHSSF++ + P L
Sbjct: 184 NQDKSIEDFAHSSFQMALSKGWPLYL 209
>CR533522-1|CAG38553.1| 414|Homo sapiens IDH1 protein.
Length = 414
Score = 308 bits (756), Expect = 1e-83
Identities = 142/206 (68%), Positives = 173/206 (83%), Gaps = 2/206 (0%)
Frame = +1
Query: 109 KIKAGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTIDCAEA 288
KI G VV++ GDEMTRIIW+LIKEKLI+P+++++LH YDLG+ENRD T+DQVT D AEA
Sbjct: 4 KISGGSVVEMQGDEMTRIIWELIKEKLIIPYVELDLHSYDLGIENRDATNDQVTKDAAEA 63
Query: 289 IKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTG 468
IKK+NVG+KCATITPDEKRVEEFKLK+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+G
Sbjct: 64 IKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSG 123
Query: 469 WDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESG-EAIKHVVHEY-KGAGVALAMF 642
W +PIIIGRHA+ DQY+ATDFVVPG G +EI + P G + + ++VH + +G GVA+ M+
Sbjct: 124 WVEPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMY 183
Query: 643 NTDASIIDFAHSSFKVXFGQKIPSVL 720
N D SI DFAHSSF++ + P L
Sbjct: 184 NQDKSIEDFAHSSFQMALSKGWPLYL 209
>CR536499-1|CAG38738.1| 414|Homo sapiens IDH1 protein.
Length = 414
Score = 308 bits (755), Expect = 2e-83
Identities = 142/206 (68%), Positives = 172/206 (83%), Gaps = 2/206 (0%)
Frame = +1
Query: 109 KIKAGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTIDCAEA 288
KI G VV++ GDEMTRIIW+LIKEKLI P+++++LH YDLG+ENRD T+DQVT D AEA
Sbjct: 4 KISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEA 63
Query: 289 IKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTG 468
IKK+NVG+KCATITPDEKRVEEFKLK+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+G
Sbjct: 64 IKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSG 123
Query: 469 WDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESG-EAIKHVVHEY-KGAGVALAMF 642
W KPIIIGRHA+ DQY+ATDFVVPG G +E+ + P G + + ++VH + +G GVA+ M+
Sbjct: 124 WVKPIIIGRHAYGDQYRATDFVVPGPGKVEMTYTPSDGTQKVTYLVHNFEEGGGVAMGMY 183
Query: 643 NTDASIIDFAHSSFKVXFGQKIPSVL 720
N D SI DFAHSSF++ + P L
Sbjct: 184 NQDKSIEDFAHSSFQMALSKGWPLYL 209
>BX537411-1|CAD97653.1| 414|Homo sapiens hypothetical protein
protein.
Length = 414
Score = 307 bits (753), Expect = 3e-83
Identities = 143/206 (69%), Positives = 171/206 (83%), Gaps = 2/206 (0%)
Frame = +1
Query: 109 KIKAGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTIDCAEA 288
KI G VV++ GDEMTRIIW+LIKEKLI P+++++LH YDLG+ENRD T+DQVT D AEA
Sbjct: 4 KISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEA 63
Query: 289 IKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTG 468
IKK+NVG+KCATITPDEKRVEEFKLK+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+G
Sbjct: 64 IKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSG 123
Query: 469 WDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESG-EAIKHVVHEYK-GAGVALAMF 642
W KPIIIGRHA+ DQY+ATDFVVPG G +EI + P G + + ++VH + G GVA+ M+
Sbjct: 124 WVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNSEGGGGVAMGMY 183
Query: 643 NTDASIIDFAHSSFKVXFGQKIPSVL 720
N D SI DFAHSSF++ + P L
Sbjct: 184 NQDKSIEDFAHSSFQMALSKGWPLYL 209
>X69433-1|CAA49208.1| 452|Homo sapiens isocitrate dehydrogenase
(NADP+) protein.
Length = 452
Score = 289 bits (710), Expect = 5e-78
Identities = 138/212 (65%), Positives = 161/212 (75%), Gaps = 2/212 (0%)
Frame = +1
Query: 82 YSRHRYNMSKIK-AGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTD 258
+ R Y +IK A PVV++ GDEMTRIIW IKEKLILP +DI+L +DLG+ NRD+TD
Sbjct: 34 HPRRHYADKRIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTD 93
Query: 259 DQVTIDCAEAIKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAII 438
DQVTID A A +KY+V +KCATITPDE RVEEFKLKKMWKSPNGTIRNILGGTVFRE II
Sbjct: 94 DQVTIDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPII 153
Query: 439 CKNIPRLVTGWDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESGEAIKH-VVHEYK 615
CKNIPRLV GW KPI IGRHAH DQYKATDFV AGT +++F P+ G +K V+ +
Sbjct: 154 CKNIPRLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFP 213
Query: 616 GAGVALAMFNTDASIIDFAHSSFKVXFGQKIP 711
GV + M+NTD SI FAHS F+ +K P
Sbjct: 214 AGGVGMGMYNTDESISGFAHSCFQYAIQKKWP 245
>BC071828-1|AAH71828.1| 452|Homo sapiens isocitrate dehydrogenase 2
(NADP+), mitochondrial protein.
Length = 452
Score = 289 bits (709), Expect = 7e-78
Identities = 138/210 (65%), Positives = 160/210 (76%), Gaps = 2/210 (0%)
Frame = +1
Query: 88 RHRYNMSKIK-AGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQ 264
R Y +IK A PVV++ GDEMTRIIW IKEKLILP +DI+L +DLG+ NRD+TDDQ
Sbjct: 36 RRHYADKRIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQ 95
Query: 265 VTIDCAEAIKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICK 444
VTID A A +KY+V +KCATITPDE RVEEFKLKKMWKSPNGTIRNILGGTVFRE IICK
Sbjct: 96 VTIDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICK 155
Query: 445 NIPRLVTGWDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESGEAIKH-VVHEYKGA 621
NIPRLV GW KPI IGRHAH DQYKATDFV AGT +++F P+ G +K V+ +
Sbjct: 156 NIPRLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAG 215
Query: 622 GVALAMFNTDASIIDFAHSSFKVXFGQKIP 711
GV + M+NTD SI FAHS F+ +K P
Sbjct: 216 GVGMGMYNTDESISGFAHSCFQYAIQKKWP 245
>BC009244-1|AAH09244.1| 452|Homo sapiens isocitrate dehydrogenase 2
(NADP+), mitochondrial protein.
Length = 452
Score = 289 bits (709), Expect = 7e-78
Identities = 138/210 (65%), Positives = 160/210 (76%), Gaps = 2/210 (0%)
Frame = +1
Query: 88 RHRYNMSKIK-AGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQ 264
R Y +IK A PVV++ GDEMTRIIW IKEKLILP +DI+L +DLG+ NRD+TDDQ
Sbjct: 36 RRHYADKRIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQ 95
Query: 265 VTIDCAEAIKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICK 444
VTID A A +KY+V +KCATITPDE RVEEFKLKKMWKSPNGTIRNILGGTVFRE IICK
Sbjct: 96 VTIDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICK 155
Query: 445 NIPRLVTGWDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESGEAIKH-VVHEYKGA 621
NIPRLV GW KPI IGRHAH DQYKATDFV AGT +++F P+ G +K V+ +
Sbjct: 156 NIPRLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAG 215
Query: 622 GVALAMFNTDASIIDFAHSSFKVXFGQKIP 711
GV + M+NTD SI FAHS F+ +K P
Sbjct: 216 GVGMGMYNTDESISGFAHSCFQYAIQKKWP 245
>AK222916-1|BAD96636.1| 452|Homo sapiens isocitrate dehydrogenase 2
(NADP+), mitochondrial precursor variant protein.
Length = 452
Score = 289 bits (709), Expect = 7e-78
Identities = 138/210 (65%), Positives = 160/210 (76%), Gaps = 2/210 (0%)
Frame = +1
Query: 88 RHRYNMSKIK-AGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQ 264
R Y +IK A PVV++ GDEMTRIIW IKEKLILP +DI+L +DLG+ NRD+TDDQ
Sbjct: 36 RRHYADKRIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQ 95
Query: 265 VTIDCAEAIKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICK 444
VTID A A +KY+V +KCATITPDE RVEEFKLKKMWKSPNGTIRNILGGTVFRE IICK
Sbjct: 96 VTIDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICK 155
Query: 445 NIPRLVTGWDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESGEAIKH-VVHEYKGA 621
NIPRLV GW KPI IGRHAH DQYKATDFV AGT +++F P+ G +K V+ +
Sbjct: 156 NIPRLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAG 215
Query: 622 GVALAMFNTDASIIDFAHSSFKVXFGQKIP 711
GV + M+NTD SI FAHS F+ +K P
Sbjct: 216 GVGMGMYNTDESISGFAHSCFQYAIQKKWP 245
>DQ403082-1|ABD77215.1| 371|Homo sapiens isocitrate dehydrogenase 1
protein.
Length = 371
Score = 269 bits (659), Expect = 8e-72
Identities = 124/180 (68%), Positives = 150/180 (83%), Gaps = 2/180 (1%)
Frame = +1
Query: 187 LILPFLDIELHVYDLGMENRDKTDDQVTIDCAEAIKKYNVGIKCATITPDEKRVEEFKLK 366
LI P+++++LH YDLG+ENRD T+DQVT D AEAIKK+NVG+KCATITPDEKRVEEFKLK
Sbjct: 1 LIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFKLK 60
Query: 367 KMWKSPNGTIRNILGGTVFREAIICKNIPRLVTGWDKPIIIGRHAHADQYKATDFVVPGA 546
+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+GW KPIIIGRHA+ DQY+ATDFVVPG
Sbjct: 61 QMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGP 120
Query: 547 GTLEIIFKPESG-EAIKHVVHEY-KGAGVALAMFNTDASIIDFAHSSFKVXFGQKIPSVL 720
G +EI + P G + + ++VH + +G GVA+ M+N D SI DFAHSSF++ + P L
Sbjct: 121 GKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYL 180
>U52144-1|AAC50455.1| 419|Homo sapiens isocitrate dehydrogenase
protein.
Length = 419
Score = 242 bits (593), Expect = 8e-64
Identities = 112/171 (65%), Positives = 131/171 (76%), Gaps = 1/171 (0%)
Frame = +1
Query: 202 LDIELHVYDLGMENRDKTDDQVTIDCAEAIKKYNVGIKCATITPDEKRVEEFKLKKMWKS 381
LD++L +DLG+ NRD+TDDQVTID A A +KY+V +KCATITPDE RVEEFKLKKMWKS
Sbjct: 42 LDVQLKYFDLGLPNRDQTDDQVTIDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKS 101
Query: 382 PNGTIRNILGGTVFREAIICKNIPRLVTGWDKPIIIGRHAHADQYKATDFVVPGAGTLEI 561
PNGTIRNI GGTVFRE IICKNIPRLV GW KPI IGRHAH DQYKATDFV AGT ++
Sbjct: 102 PNGTIRNIHGGTVFREPIICKNIPRLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKM 161
Query: 562 IFKPESGEAIKH-VVHEYKGAGVALAMFNTDASIIDFAHSSFKVXFGQKIP 711
+F P+ G +K V+ + GV + M+NTD SI FAHS F+ +K P
Sbjct: 162 VFTPKDGSGVKEWEVYNFPAGGVGMGMYNTDESISGFAHSCFQYAIQKKWP 212
>U62389-1|AAB17375.1| 154|Homo sapiens putative cytosolic
NADP-dependent isocitrate dehydrogenase protein.
Length = 154
Score = 144 bits (348), Expect = 4e-34
Identities = 68/110 (61%), Positives = 84/110 (76%), Gaps = 2/110 (1%)
Frame = +1
Query: 397 RNILGGTVFREAIICKNIPRLVTGWDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPE 576
RNILGGTVF EAIICKNIPRLV+GW KPIIIGRHA+ DQY+ATDFVVPG G +EI + P
Sbjct: 1 RNILGGTVFXEAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPS 60
Query: 577 SG-EAIKHVVHEY-KGAGVALAMFNTDASIIDFAHSSFKVXFGQKIPSVL 720
G + + ++VH + +G GVA+ M+N D SI DFAHSSF++ + P L
Sbjct: 61 DGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMALSKGWPLYL 110
>AK090454-1|BAC03435.1| 708|Homo sapiens FLJ00375 protein protein.
Length = 708
Score = 32.3 bits (70), Expect = 1.8
Identities = 21/97 (21%), Positives = 39/97 (40%)
Frame = +1
Query: 412 GTVFREAIICKNIPRLVTGWDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESGEAI 591
G V+ ++ PR GW +P + H HADQ +P G +++ E +
Sbjct: 7 GRVWEQSWGQSGSPRAFKGWARPWLAQCHLHADQQPRAMHRMPDPGKFKLL---EQARDV 63
Query: 592 KHVVHEYKGAGVALAMFNTDASIIDFAHSSFKVXFGQ 702
+ V + ++F +++ S KV G+
Sbjct: 64 REPVRYFSSVEEVASVFPDRIFVMEAITFSVKVVSGE 100
>BC020198-1|AAH20198.1| 567|Homo sapiens MEGF10 protein protein.
Length = 567
Score = 30.3 bits (65), Expect = 7.3
Identities = 21/68 (30%), Positives = 24/68 (35%), Gaps = 3/68 (4%)
Frame = +3
Query: 459 CNRVGQTHHHWTSCSC*SIQSN*LC---CPRCWYS*NNLQT*IW*GNKTCSS*VQGCRCS 629
C G HH CSC S +C CP + N Q TC + C CS
Sbjct: 240 CQNGGVCHHVTGECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHNGGTCDAATGQCHCS 299
Query: 630 TGYV*H*C 653
GY C
Sbjct: 300 PGYTGERC 307
>AB058676-1|BAB47409.1| 1140|Homo sapiens MEGF10 protein (KIAA1780)
protein.
Length = 1140
Score = 30.3 bits (65), Expect = 7.3
Identities = 21/68 (30%), Positives = 24/68 (35%), Gaps = 3/68 (4%)
Frame = +3
Query: 459 CNRVGQTHHHWTSCSC*SIQSN*LC---CPRCWYS*NNLQT*IW*GNKTCSS*VQGCRCS 629
C G HH CSC S +C CP + N Q TC + C CS
Sbjct: 240 CQNGGVCHHVTGECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHNGGTCDAATGQCHCS 299
Query: 630 TGYV*H*C 653
GY C
Sbjct: 300 PGYTGERC 307
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 104,203,581
Number of Sequences: 237096
Number of extensions: 2301591
Number of successful extensions: 3984
Number of sequences better than 10.0: 19
Number of HSP's better than 10.0 without gapping: 3824
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3962
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8567175942
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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