Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= bmmt2a22
(741 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BT007239-1|AAP35903.1| 261|Homo sapiens hydroxysteroid (17-beta... 214 3e-55
BC008185-1|AAH08185.1| 261|Homo sapiens hydroxysteroid (17-beta... 214 3e-55
AL844527-12|CAI41840.1| 261|Homo sapiens hydroxysteroid (17-bet... 214 3e-55
AL713971-6|CAI17657.1| 261|Homo sapiens hydroxysteroid (17-beta... 214 3e-55
AL662824-24|CAI17616.1| 261|Homo sapiens hydroxysteroid (17-bet... 214 3e-55
AL645940-10|CAI18068.1| 261|Homo sapiens hydroxysteroid (17-bet... 214 3e-55
AL031228-10|CAC38444.1| 261|Homo sapiens hydroxysteroid (17-bet... 214 3e-55
D82061-1|BAA11529.1| 259|Homo sapiens a member of the short-cha... 210 4e-54
BC033650-1|AAH33650.1| 237|Homo sapiens carbonyl reductase 4 pr... 116 7e-26
BC021973-1|AAH21973.1| 237|Homo sapiens carbonyl reductase 4 pr... 116 9e-26
AK027337-1|BAB55045.1| 179|Homo sapiens protein ( Homo sapiens ... 108 2e-23
X87176-1|CAA60643.1| 736|Homo sapiens 17beta-hydroxysteroid deh... 95 2e-19
BC003098-1|AAH03098.1| 736|Homo sapiens hydroxysteroid (17-beta... 95 2e-19
AF057740-1|AAD08652.1| 736|Homo sapiens 17-beta-hydroxysteroid ... 95 2e-19
Z97054-8|CAI42653.1| 261|Homo sapiens hydroxysteroid (17-beta) ... 93 7e-19
U96132-1|AAC51812.1| 261|Homo sapiens amyloid beta-peptide bind... 93 7e-19
U73514-1|AAB68958.1| 261|Homo sapiens short-chain alcohol dehyd... 93 7e-19
CR456723-1|CAG33004.1| 261|Homo sapiens HADH2 protein. 93 7e-19
BC000372-1|AAH00372.1| 261|Homo sapiens hydroxysteroid (17-beta... 93 7e-19
AF069134-1|AAC39900.1| 261|Homo sapiens putative short-chain ty... 93 7e-19
AF037438-1|AAC16419.1| 261|Homo sapiens 17beta-hydroxysteroid d... 93 7e-19
AF035555-1|AAC15902.1| 261|Homo sapiens 17beta-hydroxysteroid d... 93 7e-19
BC095414-1|AAH95414.1| 245|Homo sapiens 3-hydroxybutyrate dehyd... 92 2e-18
BC001953-1|AAH01953.1| 245|Homo sapiens 3-hydroxybutyrate dehyd... 92 2e-18
AF164790-1|AAF80754.1| 245|Homo sapiens oxidoreductase UCPA pro... 92 2e-18
U78302-1|AAB88724.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase... 91 3e-18
U49352-1|AAB09423.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase... 91 3e-18
L76465-1|AAA89175.1| 266|Homo sapiens NAD+-dependent 15-hydroxy... 91 3e-18
L26050-1|AAA67551.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase... 91 3e-18
J05594-1|AAA89174.1| 266|Homo sapiens NAD+-dependent 15-hydroxy... 91 3e-18
BC105082-1|AAI05083.1| 335|Homo sapiens 2,4-dienoyl CoA reducta... 91 3e-18
BC105080-1|AAI05081.1| 335|Homo sapiens 2,4-dienoyl CoA reducta... 91 3e-18
AY358841-1|AAQ89200.1| 245|Homo sapiens GRLD6308 protein. 91 3e-18
AC004612-1|AAC14671.1| 335|Homo sapiens 2,4-dienoyl-CoA reducta... 91 3e-18
DQ903072-1|ABI75347.1| 266|Homo sapiens hydroxyprostaglandin de... 89 2e-17
BC018986-1|AAH18986.1| 266|Homo sapiens hydroxyprostaglandin de... 89 2e-17
BC006294-1|AAH06294.1| 270|Homo sapiens hydroxysteroid (17-beta... 87 8e-17
BC006283-1|AAH06283.1| 270|Homo sapiens hydroxysteroid (17-beta... 87 8e-17
AY358430-1|AAQ88796.1| 270|Homo sapiens ATGT502 protein. 87 8e-17
AF126781-1|AAF06940.1| 270|Homo sapiens retinal short-chain deh... 87 8e-17
BC002529-1|AAH02529.1| 303|Homo sapiens peroxisomal trans-2-eno... 84 6e-16
AF232009-1|AAF69798.1| 303|Homo sapiens peroxisomal trans 2-eno... 84 6e-16
AF212234-1|AAK14920.1| 322|Homo sapiens HPDHase protein. 84 6e-16
AC010686-2|AAY14657.1| 303|Homo sapiens unknown protein. 84 6e-16
BT006881-1|AAP35527.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 81 3e-15
BC003018-1|AAH03018.1| 243|Homo sapiens Unknown (protein for IM... 81 3e-15
BC001470-1|AAH01470.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 81 3e-15
AJ250303-1|CAB89810.1| 303|Homo sapiens peroxisomal 2-enoyl-CoA... 81 3e-15
AF515625-1|AAM54026.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 81 3e-15
AF515624-1|AAO15991.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 81 3e-15
AF515623-1|AAN59786.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 81 3e-15
AF113123-1|AAF14864.1| 244|Homo sapiens carbonyl reductase prot... 81 3e-15
AB013846-1|BAB64299.1| 244|Homo sapiens kidney dicarbonyl reduc... 81 3e-15
AY092415-1|AAM18189.1| 196|Homo sapiens endoplasmic reticulum-a... 81 4e-15
AF139841-1|AAP97273.1| 244|Homo sapiens carbonyl reductase II p... 81 4e-15
DQ344810-1|ABD75823.1| 278|Homo sapiens NADP(H)-dependent retin... 81 5e-15
BC003019-1|AAH03019.1| 278|Homo sapiens dehydrogenase/reductase... 81 5e-15
AY358638-1|AAQ89001.1| 278|Homo sapiens SCAD-SRL protein. 81 5e-15
AB045131-1|BAB18775.1| 260|Homo sapiens NADPH-dependent retinol... 81 5e-15
AF044127-1|AAD02292.1| 260|Homo sapiens peroxisomal short-chain... 80 7e-15
AK001870-1|BAA91953.1| 278|Homo sapiens protein ( Homo sapiens ... 79 2e-14
AF064256-1|AAQ13444.1| 278|Homo sapiens Hep27-like protein prot... 78 3e-14
BC010740-1|AAH10740.1| 292|Homo sapiens 2,4-dienoyl CoA reducta... 76 1e-13
BC002786-1|AAH02786.1| 300|Homo sapiens dehydrogenase/reductase... 76 1e-13
AL023881-5|CAB92744.1| 292|Homo sapiens 2,4-dienoyl CoA reducta... 76 1e-13
AJ293009-1|CAC05664.1| 292|Homo sapiens peroxisomal 2,4-dienoyl... 76 1e-13
AE006463-11|AAK61231.1| 292|Homo sapiens 2-4-dienoyl-Coenzyme A... 76 1e-13
U31875-1|AAA82048.1| 280|Homo sapiens Hep27 protein protein. 75 4e-13
BC009830-1|AAH09830.1| 336|Homo sapiens retinol dehydrogenase 1... 75 4e-13
BC007339-1|AAH07339.2| 271|Homo sapiens DHRS2 protein protein. 75 4e-13
AY358511-1|AAQ88875.1| 336|Homo sapiens PAN2 protein. 75 4e-13
AF244132-1|AAG33703.1| 280|Homo sapiens short-chain alcohol deh... 75 4e-13
AF237952-1|AAG12190.1| 336|Homo sapiens PAN2 protein. 75 4e-13
AC079148-1|AAX93259.1| 336|Homo sapiens unknown protein. 75 4e-13
Z97054-7|CAI42652.1| 252|Homo sapiens hydroxysteroid (17-beta) ... 74 5e-13
BC008708-1|AAH08708.1| 252|Homo sapiens hydroxysteroid (17-beta... 74 5e-13
BC011964-1|AAH11964.1| 343|Homo sapiens 3-hydroxybutyrate dehyd... 73 8e-13
AK222857-1|BAD96577.1| 280|Homo sapiens dehydrogenase/reductase... 73 1e-12
BC019317-1|AAH19317.1| 343|Homo sapiens 3-hydroxybutyrate dehyd... 72 2e-12
BC005844-1|AAH05844.1| 343|Homo sapiens 3-hydroxybutyrate dehyd... 72 2e-12
BC002731-1|AAH02731.2| 260|Homo sapiens short-chain dehydrogena... 72 2e-12
AY358712-1|AAQ89074.1| 260|Homo sapiens ARPG836 protein. 72 2e-12
BC112305-1|AAI12306.1| 300|Homo sapiens hydroxysteroid (17-beta... 71 6e-12
BC112303-1|AAI12304.1| 300|Homo sapiens hydroxysteroid (17-beta... 71 6e-12
AY358575-1|AAQ88938.1| 300|Homo sapiens NIIL497 protein. 71 6e-12
AY268355-1|AAP42289.1| 300|Homo sapiens short-chain dehydrogena... 71 6e-12
AY186249-1|AAO72313.1| 300|Homo sapiens 17-beta hydroxysteroid ... 71 6e-12
AB073347-1|BAD38632.1| 300|Homo sapiens putative protein produc... 71 6e-12
X82460-1|CAA57843.1| 178|Homo sapiens 15-hydroxy prostaglandin ... 70 1e-11
BC028298-1|AAH28298.1| 318|Homo sapiens retinol dehydrogenase 5... 67 5e-11
AF057034-1|AAC39922.1| 317|Homo sapiens sterol/retinol dehydrog... 67 5e-11
CR457124-1|CAG33405.1| 325|Homo sapiens DKFZp566O084 protein. 67 7e-11
BC009679-1|AAH09679.1| 325|Homo sapiens dehydrogenase/reductase... 67 7e-11
BC004126-1|AAH04126.1| 325|Homo sapiens dehydrogenase/reductase... 67 7e-11
AY358498-1|AAQ88862.1| 310|Homo sapiens DFIT212 protein. 67 7e-11
AF151851-1|AAD34088.1| 291|Homo sapiens CGI-93 protein protein. 67 7e-11
BC067131-1|AAH67131.1| 341|Homo sapiens retinol dehydrogenase 1... 66 9e-11
BC064525-1|AAH64525.1| 309|Homo sapiens epidermal retinal dehyd... 66 9e-11
BC037219-1|AAH37219.2| 309|Homo sapiens epidermal retinal dehyd... 66 9e-11
AY358270-1|AAQ88637.1| 341|Homo sapiens RDH10 protein. 66 9e-11
AF456765-1|AAN64747.1| 341|Homo sapiens retinol dehydrogenase 1... 66 9e-11
X63657-1|CAA45197.1| 332|Homo sapiens FVT1 protein. 66 1e-10
M93107-1|AAA58352.1| 343|Homo sapiens (R)-3-hydroxybutyrate deh... 66 1e-10
BT006782-1|AAP35428.1| 332|Homo sapiens follicular lymphoma var... 66 1e-10
BC008797-1|AAH08797.1| 332|Homo sapiens follicular lymphoma var... 66 1e-10
U43559-1|AAC50725.1| 318|Homo sapiens 11-cis retinol dehydrogen... 66 2e-10
AF037062-1|AAC09250.1| 318|Homo sapiens retinol dehydrogenase p... 66 2e-10
AB083038-1|BAB91014.1| 309|Homo sapiens retinal short chain deh... 65 2e-10
AY358473-1|AAQ88837.1| 331|Homo sapiens RDH13 protein. 65 3e-10
AL023881-4|CAI95592.1| 280|Homo sapiens 2,4-dienoyl CoA reducta... 65 3e-10
BC000663-1|AAH00663.2| 230|Homo sapiens dehydrogenase/reductase... 64 4e-10
AK057667-1|BAB71545.1| 231|Homo sapiens protein ( Homo sapiens ... 64 4e-10
BC008650-1|AAH08650.1| 300|Homo sapiens HSD17B11 protein protein. 63 1e-09
AK075392-1|BAC11591.1| 331|Homo sapiens protein ( Homo sapiens ... 63 1e-09
CR457309-1|CAG33590.1| 173|Homo sapiens DHRS6 protein. 62 2e-09
BC037277-1|AAH37277.1| 173|Homo sapiens BDH2 protein protein. 62 2e-09
BC036001-1|AAH36001.1| 300|Homo sapiens hydroxysteroid (17-beta... 62 2e-09
BC021673-1|AAH21673.1| 300|Homo sapiens hydroxysteroid (17-beta... 62 2e-09
BC016367-1|AAH16367.1| 300|Homo sapiens hydroxysteroid (17-beta... 62 2e-09
BC014327-1|AAH14327.1| 300|Homo sapiens hydroxysteroid (17-beta... 62 2e-09
AY358553-1|AAQ88917.1| 300|Homo sapiens KFLL207 protein. 62 2e-09
AK023323-1|BAB14526.1| 173|Homo sapiens protein ( Homo sapiens ... 62 2e-09
AF273056-1|AAM44459.1| 300|Homo sapiens CTCL tumor antigen HD-C... 62 2e-09
AF126780-1|AAF06939.1| 300|Homo sapiens retinal short-chain deh... 62 2e-09
L40802-1|AAC41917.1| 387|Homo sapiens 17-hydroxysteroid dehydro... 61 4e-09
L11708-1|AAA03562.1| 387|Homo sapiens 17 beta hydroxysteroid de... 61 4e-09
CR457180-1|CAG33461.1| 318|Homo sapiens RDH11 protein. 61 4e-09
BC059170-1|AAH59170.1| 387|Homo sapiens hydroxysteroid (17-beta... 61 4e-09
BC037302-1|AAH37302.1| 318|Homo sapiens retinol dehydrogenase 1... 61 4e-09
BC026274-1|AAH26274.1| 318|Homo sapiens retinol dehydrogenase 1... 61 4e-09
BC011727-1|AAH11727.1| 318|Homo sapiens RDH11 protein protein. 61 4e-09
BC009581-1|AAH09581.1| 387|Homo sapiens hydroxysteroid (17-beta... 61 4e-09
BC000112-1|AAH00112.1| 318|Homo sapiens retinol dehydrogenase 1... 61 4e-09
AY325910-1|AAP78485.1| 387|Homo sapiens hydroxysteroid (17-beta... 61 4e-09
AK223001-1|BAD96721.1| 387|Homo sapiens hydroxysteroid (17-beta... 61 4e-09
AK075348-1|BAC11560.1| 300|Homo sapiens protein ( Homo sapiens ... 61 4e-09
AF395068-1|AAK72049.1| 318|Homo sapiens HCV core-binding protei... 61 4e-09
AF167438-1|AAF89632.1| 318|Homo sapiens androgen-regulated shor... 61 4e-09
AF151840-1|AAD34077.1| 318|Homo sapiens CGI-82 protein protein. 61 4e-09
AF086735-1|AAC72923.1| 317|Homo sapiens retinol dehydrogenase p... 61 4e-09
BC058883-1|AAH58883.1| 319|Homo sapiens dehydrogenase/reductase... 60 1e-08
AY359046-1|AAQ89405.1| 319|Homo sapiens RDHL protein. 60 1e-08
AY017349-1|AAG49422.1| 319|Homo sapiens retinol dehydrogenase p... 60 1e-08
AF529288-1|AAN04010.1| 319|Homo sapiens microsomal NADP-depende... 60 1e-08
AF529287-1|AAN04009.1| 319|Homo sapiens microsomal NADP-depende... 60 1e-08
AF529286-1|AAN04008.1| 319|Homo sapiens microsomal NADP-depende... 60 1e-08
AF343729-1|AAK37528.1| 319|Homo sapiens 3-alpha hydroxysteroid ... 60 1e-08
AF295380-1|AAL37037.1| 319|Homo sapiens short-chain dehydrogena... 60 1e-08
AC008177-2|AAY24306.1| 245|Homo sapiens unknown protein. 60 1e-08
BC095451-1|AAH95451.1| 418|Homo sapiens hydroxysteroid dehydrog... 59 2e-08
AY093428-1|AAM14670.1| 418|Homo sapiens hydroxysteroid dehydrog... 59 2e-08
AL162732-1|CAM17152.1| 418|Homo sapiens hydroxysteroid dehydrog... 59 2e-08
U89717-1|AAB93668.1| 318|Homo sapiens 9-cis-retinol specific de... 58 3e-08
BC011968-1|AAH11968.1| 244|Homo sapiens DECR2 protein protein. 58 3e-08
BC020710-1|AAH20710.1| 317|Homo sapiens hydroxysteroid (17-beta... 58 4e-08
AF223225-1|AAF81017.1| 317|Homo sapiens 3-hydroxysteroid epimer... 58 4e-08
AF016509-1|AAB67236.1| 317|Homo sapiens oxidoreductase protein. 58 4e-08
BC007337-1|AAH07337.1| 339|Homo sapiens dehydrogenase/reductase... 57 6e-08
BC000637-1|AAH00637.1| 339|Homo sapiens dehydrogenase/reductase... 57 6e-08
AY359031-1|AAQ89390.1| 289|Homo sapiens oxidoreductase/S-2 H pr... 57 6e-08
AF151844-1|AAD34081.1| 339|Homo sapiens CGI-86 protein protein. 57 6e-08
AF126782-1|AAF06941.1| 289|Homo sapiens retinal short-chain deh... 57 6e-08
AK058159-1|BAB71694.1| 313|Homo sapiens protein ( Homo sapiens ... 56 1e-07
AF418205-1|AAN32660.1| 313|Homo sapiens dehydrogenase/reductase... 56 1e-07
BC014057-1|AAH14057.1| 313|Homo sapiens DHRS1 protein protein. 56 1e-07
BC104218-1|AAI04219.1| 330|Homo sapiens hydroxysteroid dehydrog... 56 2e-07
BC015943-1|AAH15943.1| 313|Homo sapiens DHRS1 protein protein. 56 2e-07
AY028377-1|AAK16927.1| 309|Homo sapiens steroid dehydrogenase-l... 56 2e-07
AK074878-1|BAC11262.1| 330|Homo sapiens protein ( Homo sapiens ... 56 2e-07
AF237684-1|AAK15047.1| 309|Homo sapiens steroid dehydrogenase-l... 56 2e-07
BC101553-1|AAI01554.1| 313|Homo sapiens orphan short-chain dehy... 55 2e-07
BC101551-1|AAI01552.1| 313|Homo sapiens orphan short-chain dehy... 55 2e-07
BC025724-1|AAH25724.1| 316|Homo sapiens retinol dehydrogenase 1... 55 2e-07
AY044434-1|AAK95856.1| 313|Homo sapiens retinol dehydrogenase s... 55 2e-07
AK054835-1|BAB70811.1| 316|Homo sapiens (ARSDR1) mRNA. protein. 55 2e-07
BC106917-1|AAI06918.1| 330|Homo sapiens hydroxysteroid dehydrog... 54 4e-07
BC104219-1|AAI04220.1| 330|Homo sapiens hydroxysteroid dehydrog... 54 4e-07
BC018084-1|AAH18084.2| 330|Homo sapiens hydroxysteroid dehydrog... 54 4e-07
AF069291-3|AAC62233.1| 188|Homo sapiens 2,4-dienoyl-CoA reducta... 54 5e-07
U63296-1|AAB53034.1| 143|Homo sapiens 15-hydroxyprostaglandin d... 54 7e-07
AF240698-1|AAF82748.1| 279|Homo sapiens retinol dehydrogenase h... 54 7e-07
AY186250-1|AAO72314.1| 264|Homo sapiens 17-beta hydroxysteroid ... 53 1e-06
U05659-1|AAC50066.1| 310|Homo sapiens 17beta-hydroxysteroid deh... 52 2e-06
CR541894-1|CAG46692.1| 310|Homo sapiens HSD17B3 protein. 52 2e-06
CR457356-1|CAG33637.1| 181|Homo sapiens MGC4172 protein. 52 2e-06
BC034281-1|AAH34281.1| 310|Homo sapiens hydroxysteroid (17-beta... 52 2e-06
AY341031-1|AAP88937.1| 310|Homo sapiens hydroxysteroid (17-beta... 52 2e-06
AL160269-3|CAH71615.1| 310|Homo sapiens hydroxysteroid (17-beta... 52 2e-06
AK026196-1|BAB15390.1| 181|Homo sapiens protein ( Homo sapiens ... 52 2e-06
DQ325464-1|ABC61320.1| 244|Homo sapiens NADP(H)-dependent retin... 52 2e-06
BC012043-1|AAH12043.1| 312|Homo sapiens hydroxysteroid (17-beta... 51 4e-06
AK222881-1|BAD96601.1| 312|Homo sapiens steroid dehydrogenase h... 51 4e-06
M76665-1|AAC31757.1| 292|Homo sapiens 11-beta-hydroxysteroid de... 51 5e-06
BC012593-1|AAH12593.1| 292|Homo sapiens hydroxysteroid (11-beta... 51 5e-06
AY044084-1|AAK83653.1| 292|Homo sapiens 11-beta hydroxysteroid ... 51 5e-06
AL031316-4|CAI20063.1| 292|Homo sapiens hydroxysteroid (11-beta... 51 5e-06
AL022398-8|CAA18541.2| 292|Homo sapiens hydroxysteroid (11-beta... 51 5e-06
AF229845-1|AAF63160.1| 311|Homo sapiens photoreceptor outer seg... 50 9e-06
DQ426886-1|ABD90542.1| 171|Homo sapiens retinol dehydrogenase 1... 49 2e-05
X13440-1|CAA31792.1| 328|Homo sapiens protein ( Human mRNA for ... 48 3e-05
U34879-1|AAD05019.1| 328|Homo sapiens 17-beta-hydroxysteroid de... 48 3e-05
M84472-1|AAB16942.1| 328|Homo sapiens 17-beta-hydroxysteroid de... 48 3e-05
M36263-1|AAA35600.1| 328|Homo sapiens protein ( Human placental... 48 3e-05
M27138-1|AAB16941.1| 328|Homo sapiens protein ( Human estradiol... 48 3e-05
BC111935-1|AAI11936.1| 328|Homo sapiens hydroxysteroid (17-beta... 48 3e-05
BC104752-1|AAI04753.1| 328|Homo sapiens hydroxysteroid (17-beta... 48 3e-05
BT019371-1|AAV38178.1| 260|Homo sapiens hydroxysteroid (17-beta... 48 4e-05
BC002730-1|AAH02730.1| 302|Homo sapiens dehydrogenase/reductase... 48 4e-05
AL645761-1|CAI14999.1| 302|Homo sapiens dehydrogenase/reductase... 48 4e-05
AL513016-1|CAH74172.1| 302|Homo sapiens dehydrogenase/reductase... 48 4e-05
AK222593-1|BAD96313.1| 302|Homo sapiens dehydrogenase/reductase... 48 4e-05
AF179237-1|AAD55402.1| 302|Homo sapiens short-chain dehydrogena... 48 4e-05
AF061741-1|AAC63263.1| 302|Homo sapiens retinal short-chain deh... 48 4e-05
DQ088988-1|AAZ85982.1| 118|Homo sapiens DHRS4L2 isoform 2 protein. 47 6e-05
Z97054-9|CAI42651.1| 169|Homo sapiens hydroxysteroid (17-beta) ... 46 1e-04
CR381696-2|CAI95410.1| 268|Homo sapiens dehydrogenase/reductase... 45 2e-04
BX649443-2|CAI95431.1| 268|Homo sapiens dehydrogenase/reductase... 45 2e-04
BC019696-1|AAH19696.2| 330|Homo sapiens DHRSX protein protein. 45 2e-04
AY358849-1|AAQ89208.1| 330|Homo sapiens ALTE protein. 45 2e-04
BC032340-1|AAH32340.1| 330|Homo sapiens dehydrogenase/reductase... 45 3e-04
BC026024-1|AAH26024.1| 312|Homo sapiens DHRS12 protein protein. 45 3e-04
AJ293620-1|CAC82170.1| 330|Homo sapiens putative oxidoreductase... 45 3e-04
BC009881-1|AAH09881.1| 260|Homo sapiens retinol dehydrogenase 1... 44 4e-04
U14631-1|AAA91969.1| 405|Homo sapiens 11 beta-hydroxysteroid de... 44 6e-04
U26726-1|AAC50356.1| 405|Homo sapiens 11-beta-hydroxysteroid de... 43 0.001
EF694683-1|ABS29267.1| 405|Homo sapiens hydroxysteroid (11-beta... 43 0.001
BC064536-1|AAH64536.1| 405|Homo sapiens hydroxysteroid (11-beta... 43 0.001
BC036780-1|AAH36780.1| 405|Homo sapiens hydroxysteroid (11-beta... 43 0.001
U89281-1|AAB88252.1| 317|Homo sapiens oxidative 3 alpha hydroxy... 42 0.002
U27317-1|AAB48544.1| 405|Homo sapiens 11 beta-hydroxysteroid de... 42 0.002
AF177983-1|AAF29493.1| 72|Homo sapiens NAD+-dependent 15-hydro... 42 0.002
M76231-1|AAA60314.1| 261|Homo sapiens sepiapterin reductase pro... 41 0.005
CR381696-3|CAI95411.1| 266|Homo sapiens dehydrogenase/reductase... 41 0.005
BX649443-3|CAI95432.1| 266|Homo sapiens dehydrogenase/reductase... 41 0.005
BC017310-1|AAH17310.1| 261|Homo sapiens sepiapterin reductase (... 41 0.005
AY358566-1|AAQ88929.1| 377|Homo sapiens EALL419 protein. 40 0.009
AF325432-1|AAL05449.1| 414|Homo sapiens WW domain-containing ox... 40 0.012
AF211943-1|AAF27049.1| 414|Homo sapiens WW domain-containing pr... 40 0.012
AK024022-1|BAB14782.1| 219|Homo sapiens protein ( Homo sapiens ... 39 0.016
AY444559-1|AAS68535.1| 265|Homo sapiens retinal short chain deh... 39 0.022
AB209653-1|BAD92890.1| 166|Homo sapiens dehydrogenase/reductase... 39 0.022
AY256821-1|AAP94227.1| 526|Homo sapiens WOX8 isoform 8 protein. 38 0.038
AF227527-1|AAF82054.1| 414|Homo sapiens FOR II protein protein. 38 0.038
AF227526-1|AAF82053.1| 363|Homo sapiens FOR I protein protein. 38 0.038
AF162767-1|AAF14537.1| 341|Homo sapiens 17beta-hydroxysteroid d... 37 0.066
AK027882-1|BAB55429.1| 177|Homo sapiens protein ( Homo sapiens ... 36 0.12
BT007075-1|AAP35738.1| 341|Homo sapiens hydroxysteroid (17-beta... 36 0.15
BC065246-1|AAH65246.1| 341|Homo sapiens hydroxysteroid (17-beta... 36 0.15
BC007068-1|AAH07068.1| 341|Homo sapiens hydroxysteroid (17-beta... 36 0.15
AY358962-1|AAQ89321.1| 341|Homo sapiens HSD17B7 protein. 36 0.15
AL445197-8|CAI15947.1| 341|Homo sapiens hydroxysteroid (17-beta... 36 0.15
AL445197-7|CAI15946.1| 111|Homo sapiens hydroxysteroid (17-beta... 36 0.15
AL392003-2|CAI13457.1| 341|Homo sapiens hydroxysteroid (17-beta... 36 0.15
AK022929-1|BAB14312.1| 155|Homo sapiens protein ( Homo sapiens ... 36 0.15
AJ249179-1|CAC20418.1| 341|Homo sapiens 17beta-hydroxysteroid d... 36 0.15
AF145023-1|AAP97275.1| 341|Homo sapiens ovarian-specific protei... 36 0.15
AF098786-1|AAF09266.2| 341|Homo sapiens 17 beta-hydroxysteroid ... 36 0.15
BC004331-1|AAH04331.1| 345|Homo sapiens HSDL2 protein protein. 35 0.27
AL162732-2|CAM17151.1| 345|Homo sapiens hydroxysteroid dehydrog... 35 0.27
AY616182-1|AAT70757.1| 188|Homo sapiens NADP(H)-dependent retin... 35 0.35
AY071856-1|AAL61824.2| 174|Homo sapiens NADP-dependent retinol ... 35 0.35
AC092630-1|AAY15035.1| 198|Homo sapiens unknown protein. 35 0.35
AB017547-1|BAA34534.1| 198|Homo sapiens sepiapterin reductase p... 35 0.35
AY313894-1|AAP83166.1| 315|Homo sapiens short-chain dehydrogena... 34 0.47
AY268352-1|AAP42286.1| 286|Homo sapiens short-chain dehydrogena... 34 0.47
CR457145-1|CAG33426.1| 157|Homo sapiens PECR protein. 33 0.81
AF325432-2|AAL05451.1| 213|Homo sapiens aberrant WW domain-cont... 32 2.5
EF462915-1|ABO43035.1| 277|Homo sapiens carbonyl reductase 3 pr... 31 3.3
CR541709-1|CAG46510.1| 277|Homo sapiens CBR3 protein. 31 3.3
BT007445-1|AAP36113.1| 234|Homo sapiens WW domain containing ox... 31 3.3
BC003184-1|AAH03184.1| 234|Homo sapiens WWOX protein protein. 31 3.3
BC002812-1|AAH02812.1| 277|Homo sapiens carbonyl reductase 3 pr... 31 3.3
AP001725-1|BAA95547.1| 277|Homo sapiens carbonyl reductase (NAD... 31 3.3
AP000689-1|BAA89425.1| 277|Homo sapiens carbonyl reductase 3 pr... 31 3.3
AK223429-1|BAD97149.1| 277|Homo sapiens carbonyl reductase 3 va... 31 3.3
AF395123-1|AAK81727.1| 234|Homo sapiens WWOXdelta6-8 protein. 31 3.3
AF325429-1|AAL05450.1| 189|Homo sapiens WW domain-containing ox... 31 3.3
AF227528-1|AAF82055.1| 189|Homo sapiens FOR III protein protein. 31 3.3
AF187015-1|AAF31694.1| 189|Homo sapiens truncated WW-domain oxi... 31 3.3
AB124847-1|BAE45939.1| 277|Homo sapiens carbonyl reductase 3 pr... 31 3.3
AB041012-1|BAD74062.1| 277|Homo sapiens NADPH-dependent carbony... 31 3.3
AB004854-1|BAA33500.1| 277|Homo sapiens carbonyl reductase 3 pr... 31 3.3
AB003151-2|BAA34207.1| 277|Homo sapiens carbonyl reductase 3 pr... 31 3.3
AJ250550-1|CAC88111.1| 341|Homo sapiens 17beta hydroxysteroid d... 31 4.3
AF007197-1|AAB84381.1| 335|Homo sapiens mucin protein. 31 4.3
AF007193-1|AAC02271.1| 441|Homo sapiens mucin protein. 31 4.3
BC012536-1|AAH12536.1| 98|Homo sapiens HSD17B12 protein protein. 30 7.6
>BT007239-1|AAP35903.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 214 bits (522), Expect = 3e-55
Identities = 110/213 (51%), Positives = 150/213 (70%), Gaps = 3/213 (1%)
Frame = +3
Query: 111 LALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGE---EHS 281
LALVTGAGSGIGRA L+ EGATV A D AA +T++ PG+ G H+
Sbjct: 13 LALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGG--PGSKEGPPRGNHA 70
Query: 282 AVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLKG 461
A + DVS ++A + L++ + +PP ++V+ AGIT+D ++L +SE+D+D V+ VNLKG
Sbjct: 71 AFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKG 130
Query: 462 TFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELGKF 641
TFLV QA A+A+ + GSIINISSIVGK GN+GQTNYA+SKAGV+ +TQ+AA+ELG+
Sbjct: 131 TFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRH 190
Query: 642 NIRVNAILPGFIDTPIIKTVPDKVKETDCEISP 740
IR N++LPGFI TP+ + VP KV + E+ P
Sbjct: 191 GIRCNSVLPGFIATPMTQKVPQKVVDKITEMIP 223
>BC008185-1|AAH08185.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 214 bits (522), Expect = 3e-55
Identities = 110/213 (51%), Positives = 150/213 (70%), Gaps = 3/213 (1%)
Frame = +3
Query: 111 LALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGE---EHS 281
LALVTGAGSGIGRA L+ EGATV A D AA +T++ PG+ G H+
Sbjct: 13 LALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGG--PGSKEGPPRGNHA 70
Query: 282 AVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLKG 461
A + DVS ++A + L++ + +PP ++V+ AGIT+D ++L +SE+D+D V+ VNLKG
Sbjct: 71 AFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKG 130
Query: 462 TFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELGKF 641
TFLV QA A+A+ + GSIINISSIVGK GN+GQTNYA+SKAGV+ +TQ+AA+ELG+
Sbjct: 131 TFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRH 190
Query: 642 NIRVNAILPGFIDTPIIKTVPDKVKETDCEISP 740
IR N++LPGFI TP+ + VP KV + E+ P
Sbjct: 191 GIRCNSVLPGFIATPMTQKVPQKVVDKITEMIP 223
>AL844527-12|CAI41840.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 214 bits (522), Expect = 3e-55
Identities = 110/213 (51%), Positives = 150/213 (70%), Gaps = 3/213 (1%)
Frame = +3
Query: 111 LALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGE---EHS 281
LALVTGAGSGIGRA L+ EGATV A D AA +T++ PG+ G H+
Sbjct: 13 LALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGG--PGSKEGPPRGNHA 70
Query: 282 AVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLKG 461
A + DVS ++A + L++ + +PP ++V+ AGIT+D ++L +SE+D+D V+ VNLKG
Sbjct: 71 AFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKG 130
Query: 462 TFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELGKF 641
TFLV QA A+A+ + GSIINISSIVGK GN+GQTNYA+SKAGV+ +TQ+AA+ELG+
Sbjct: 131 TFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRH 190
Query: 642 NIRVNAILPGFIDTPIIKTVPDKVKETDCEISP 740
IR N++LPGFI TP+ + VP KV + E+ P
Sbjct: 191 GIRCNSVLPGFIATPMTQKVPQKVVDKITEMIP 223
>AL713971-6|CAI17657.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 214 bits (522), Expect = 3e-55
Identities = 110/213 (51%), Positives = 150/213 (70%), Gaps = 3/213 (1%)
Frame = +3
Query: 111 LALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGE---EHS 281
LALVTGAGSGIGRA L+ EGATV A D AA +T++ PG+ G H+
Sbjct: 13 LALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGG--PGSKEGPPRGNHA 70
Query: 282 AVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLKG 461
A + DVS ++A + L++ + +PP ++V+ AGIT+D ++L +SE+D+D V+ VNLKG
Sbjct: 71 AFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKG 130
Query: 462 TFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELGKF 641
TFLV QA A+A+ + GSIINISSIVGK GN+GQTNYA+SKAGV+ +TQ+AA+ELG+
Sbjct: 131 TFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRH 190
Query: 642 NIRVNAILPGFIDTPIIKTVPDKVKETDCEISP 740
IR N++LPGFI TP+ + VP KV + E+ P
Sbjct: 191 GIRCNSVLPGFIATPMTQKVPQKVVDKITEMIP 223
>AL662824-24|CAI17616.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 214 bits (522), Expect = 3e-55
Identities = 110/213 (51%), Positives = 150/213 (70%), Gaps = 3/213 (1%)
Frame = +3
Query: 111 LALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGE---EHS 281
LALVTGAGSGIGRA L+ EGATV A D AA +T++ PG+ G H+
Sbjct: 13 LALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGG--PGSKEGPPRGNHA 70
Query: 282 AVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLKG 461
A + DVS ++A + L++ + +PP ++V+ AGIT+D ++L +SE+D+D V+ VNLKG
Sbjct: 71 AFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKG 130
Query: 462 TFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELGKF 641
TFLV QA A+A+ + GSIINISSIVGK GN+GQTNYA+SKAGV+ +TQ+AA+ELG+
Sbjct: 131 TFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRH 190
Query: 642 NIRVNAILPGFIDTPIIKTVPDKVKETDCEISP 740
IR N++LPGFI TP+ + VP KV + E+ P
Sbjct: 191 GIRCNSVLPGFIATPMTQKVPQKVVDKITEMIP 223
>AL645940-10|CAI18068.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 214 bits (522), Expect = 3e-55
Identities = 110/213 (51%), Positives = 150/213 (70%), Gaps = 3/213 (1%)
Frame = +3
Query: 111 LALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGE---EHS 281
LALVTGAGSGIGRA L+ EGATV A D AA +T++ PG+ G H+
Sbjct: 13 LALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGG--PGSKEGPPRGNHA 70
Query: 282 AVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLKG 461
A + DVS ++A + L++ + +PP ++V+ AGIT+D ++L +SE+D+D V+ VNLKG
Sbjct: 71 AFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKG 130
Query: 462 TFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELGKF 641
TFLV QA A+A+ + GSIINISSIVGK GN+GQTNYA+SKAGV+ +TQ+AA+ELG+
Sbjct: 131 TFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRH 190
Query: 642 NIRVNAILPGFIDTPIIKTVPDKVKETDCEISP 740
IR N++LPGFI TP+ + VP KV + E+ P
Sbjct: 191 GIRCNSVLPGFIATPMTQKVPQKVVDKITEMIP 223
>AL031228-10|CAC38444.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 214 bits (522), Expect = 3e-55
Identities = 110/213 (51%), Positives = 150/213 (70%), Gaps = 3/213 (1%)
Frame = +3
Query: 111 LALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGE---EHS 281
LALVTGAGSGIGRA L+ EGATV A D AA +T++ PG+ G H+
Sbjct: 13 LALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGG--PGSKEGPPRGNHA 70
Query: 282 AVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLKG 461
A + DVS ++A + L++ + +PP ++V+ AGIT+D ++L +SE+D+D V+ VNLKG
Sbjct: 71 AFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKG 130
Query: 462 TFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELGKF 641
TFLV QA A+A+ + GSIINISSIVGK GN+GQTNYA+SKAGV+ +TQ+AA+ELG+
Sbjct: 131 TFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRH 190
Query: 642 NIRVNAILPGFIDTPIIKTVPDKVKETDCEISP 740
IR N++LPGFI TP+ + VP KV + E+ P
Sbjct: 191 GIRCNSVLPGFIATPMTQKVPQKVVDKITEMIP 223
>D82061-1|BAA11529.1| 259|Homo sapiens a member of the short-chain
alcohol dehydrogenase family protein.
Length = 259
Score = 210 bits (513), Expect = 4e-54
Identities = 109/213 (51%), Positives = 148/213 (69%), Gaps = 3/213 (1%)
Frame = +3
Query: 111 LALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGE---EHS 281
LALVTGAGSGIGRA L+ EGATV A D AA +T++ PG+ G H+
Sbjct: 11 LALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGG--PGSKEGPPRGNHA 68
Query: 282 AVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLKG 461
A + DVS ++A + L++ + +PP ++V+ AGIT+D ++L +S +D+D V+ VNLKG
Sbjct: 69 AFQADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSRDDWDKVIAVNLKG 128
Query: 462 TFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELGKF 641
TFLV QA A+A+ + GSIINISSIVGK GN+GQTNYA+SKAGV+ +TQ+AA+ELG+
Sbjct: 129 TFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRH 188
Query: 642 NIRVNAILPGFIDTPIIKTVPDKVKETDCEISP 740
I N++LPGFI TP+ K VP KV + E+ P
Sbjct: 189 GIPCNSVLPGFIATPMTKKVPKKVVDKITEMIP 221
>BC033650-1|AAH33650.1| 237|Homo sapiens carbonyl reductase 4
protein.
Length = 237
Score = 116 bits (280), Expect = 7e-26
Identities = 69/201 (34%), Positives = 112/201 (55%)
Frame = +3
Query: 108 RLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHSAV 287
++ V G GIGRA Q+++++G + R E A A G GG+ H A
Sbjct: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGA--------KAAAGDLGGD-HLAF 53
Query: 288 ELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLKGTF 467
DV+ VQ+ ++ L+++ +VN+AGI RD +++ ED S L+ NL G+
Sbjct: 54 SCDVAKEHDVQNTFEE-LEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSM 112
Query: 468 LVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELGKFNI 647
L +A + M + GSI+N+ SIVG GN GQ+ Y++SK G+V +++ AKE+ + I
Sbjct: 113 LTCKAAMRTMIQQQ-GGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKI 171
Query: 648 RVNAILPGFIDTPIIKTVPDK 710
RVN + PGF+ T + K + ++
Sbjct: 172 RVNVVAPGFVHTDMTKDLKEE 192
>BC021973-1|AAH21973.1| 237|Homo sapiens carbonyl reductase 4
protein.
Length = 237
Score = 116 bits (279), Expect = 9e-26
Identities = 69/201 (34%), Positives = 110/201 (54%)
Frame = +3
Query: 108 RLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHSAV 287
++ V G GIGRA Q+++++G + R E A A G GG+ H A
Sbjct: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGA--------KAAAGDLGGD-HLAF 53
Query: 288 ELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLKGTF 467
DV+ VQ+ ++ K + +VN+AGI RD +++ ED S L+ NL G+
Sbjct: 54 SCDVAKEHDVQNTFEEMEKHLGRVN-FLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSM 112
Query: 468 LVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELGKFNI 647
L +A + M + GSI+N+ SIVG GN GQ+ Y++SK G+V +++ AKE+ + I
Sbjct: 113 LTCKAAMRTMIQQQ-GGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKI 171
Query: 648 RVNAILPGFIDTPIIKTVPDK 710
RVN + PGF+ T + K + ++
Sbjct: 172 RVNVVAPGFVHTDMTKDLKEE 192
>AK027337-1|BAB55045.1| 179|Homo sapiens protein ( Homo sapiens
cDNA FLJ14431 fis, clone HEMBA1006521, weakly similar to
3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE (EC
1.1.1.100). ).
Length = 179
Score = 108 bits (260), Expect = 2e-23
Identities = 66/188 (35%), Positives = 102/188 (54%)
Frame = +3
Query: 108 RLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHSAV 287
++ V G GIGRA Q+++++G + R E A A G GG+ H A
Sbjct: 3 KVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGA--------KAAAGDLGGD-HLAF 53
Query: 288 ELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLKGTF 467
DV+ VQ+ ++ K + +VN+AGI RD +++ ED S L+ NL G+
Sbjct: 54 SCDVAKEHDVQNTFEEMEKHLGRVN-FLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSM 112
Query: 468 LVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELGKFNI 647
L +A + M + GSI+N+ SIVG GN GQ+ Y++SK G+V +++ AKE+ + I
Sbjct: 113 LTCKAAMRTMIQQQ-GGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKI 171
Query: 648 RVNAILPG 671
RVN + PG
Sbjct: 172 RVNVVAPG 179
>X87176-1|CAA60643.1| 736|Homo sapiens 17beta-hydroxysteroid
dehydrogenase protein.
Length = 736
Score = 95.1 bits (226), Expect = 2e-19
Identities = 66/191 (34%), Positives = 102/191 (53%), Gaps = 3/191 (1%)
Frame = +3
Query: 105 GRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHSA 284
GR+ LVTGAG+G+GRA ++ GA V+ D + +LA E
Sbjct: 9 GRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVG---KGSLAADKVVEEIRRR 65
Query: 285 VELDVSNSKAVQD---LVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNL 455
V+N +V++ +V+ L + + ++VN+AGI RD ++S+ED+D + V+L
Sbjct: 66 GGKAVANYDSVEEGEKVVKTALDAFGRID-VVVNNAGILRDRSFARISDEDWDIIHRVHL 124
Query: 456 KGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELG 635
+G+F V +A + M + G II SS G YGN GQ NY+++K G++ + S A E
Sbjct: 125 RGSFQVTRAAWEHMKKQKY-GRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEGR 183
Query: 636 KFNIRVNAILP 668
K NI N I P
Sbjct: 184 KSNIHCNTIAP 194
>BC003098-1|AAH03098.1| 736|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 4 protein.
Length = 736
Score = 95.1 bits (226), Expect = 2e-19
Identities = 66/191 (34%), Positives = 102/191 (53%), Gaps = 3/191 (1%)
Frame = +3
Query: 105 GRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHSA 284
GR+ LVTGAG+G+GRA ++ GA V+ D + +LA E
Sbjct: 9 GRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVG---KGSLAADKVVEEIRRR 65
Query: 285 VELDVSNSKAVQD---LVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNL 455
V+N +V++ +V+ L + + ++VN+AGI RD ++S+ED+D + V+L
Sbjct: 66 GGKAVANYDSVEEGEKVVKTALDAFGRID-VVVNNAGILRDRSFARISDEDWDIIHRVHL 124
Query: 456 KGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELG 635
+G+F V +A + M + G II SS G YGN GQ NY+++K G++ + S A E
Sbjct: 125 RGSFQVTRAAWEHMKKQKY-GRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEGR 183
Query: 636 KFNIRVNAILP 668
K NI N I P
Sbjct: 184 KSNIHCNTIAP 194
>AF057740-1|AAD08652.1| 736|Homo sapiens 17-beta-hydroxysteroid
dehydrogenase IV protein.
Length = 736
Score = 95.1 bits (226), Expect = 2e-19
Identities = 66/191 (34%), Positives = 102/191 (53%), Gaps = 3/191 (1%)
Frame = +3
Query: 105 GRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHSA 284
GR+ LVTGAG+G+GRA ++ GA V+ D + +LA E
Sbjct: 9 GRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVG---KGSLAADKVVEEIRRR 65
Query: 285 VELDVSNSKAVQD---LVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNL 455
V+N +V++ +V+ L + + ++VN+AGI RD ++S+ED+D + V+L
Sbjct: 66 GGKAVANYDSVEEGEKVVKTALDAFGRID-VVVNNAGILRDRSFARISDEDWDIIHRVHL 124
Query: 456 KGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELG 635
+G+F V +A + M + G II SS G YGN GQ NY+++K G++ + S A E
Sbjct: 125 RGSFQVTRAAWEHMKKQKY-GRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEGR 183
Query: 636 KFNIRVNAILP 668
K NI N I P
Sbjct: 184 KSNIHCNTIAP 194
>Z97054-8|CAI42653.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 10 protein.
Length = 261
Score = 93.5 bits (222), Expect = 7e-19
Identities = 70/219 (31%), Positives = 109/219 (49%), Gaps = 14/219 (6%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKY---EAAVQTIKTHTALAPGTNGG 269
V G +A++TG SG+G A + L +GA+ + D EA + + + AP
Sbjct: 8 VKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPA---- 63
Query: 270 EEHSAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGIT--RDNWMLKLSE----EDY 431
DV++ K VQ + ++ + + VN AGI + LK + ED+
Sbjct: 64 --------DVTSEKDVQTALALAKGKFGRVD-VAVNCAGIAVASKTYNLKKGQTHTLEDF 114
Query: 432 DSVLNVNLKGTFLVMQAFAKAMAESSVT-----GSIINISSIVGKYGNMGQTNYASSKAG 596
VL+VNL GTF V++ A M ++ G IIN +S+ G +GQ Y++SK G
Sbjct: 115 QRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGG 174
Query: 597 VVAMTQSAAKELGKFNIRVNAILPGFIDTPIIKTVPDKV 713
+V MT A++L IRV I PG TP++ ++P+KV
Sbjct: 175 IVGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKV 213
>U96132-1|AAC51812.1| 261|Homo sapiens amyloid beta-peptide binding
protein protein.
Length = 261
Score = 93.5 bits (222), Expect = 7e-19
Identities = 70/219 (31%), Positives = 109/219 (49%), Gaps = 14/219 (6%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKY---EAAVQTIKTHTALAPGTNGG 269
V G +A++TG SG+G A + L +GA+ + D EA + + + AP
Sbjct: 8 VKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPA---- 63
Query: 270 EEHSAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGIT--RDNWMLKLSE----EDY 431
DV++ K VQ + ++ + + VN AGI + LK + ED+
Sbjct: 64 --------DVTSEKDVQTALALAKGKFGRVD-VAVNCAGIAVASKTYNLKKGQTHTLEDF 114
Query: 432 DSVLNVNLKGTFLVMQAFAKAMAESSVT-----GSIINISSIVGKYGNMGQTNYASSKAG 596
VL+VNL GTF V++ A M ++ G IIN +S+ G +GQ Y++SK G
Sbjct: 115 QRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGG 174
Query: 597 VVAMTQSAAKELGKFNIRVNAILPGFIDTPIIKTVPDKV 713
+V MT A++L IRV I PG TP++ ++P+KV
Sbjct: 175 IVGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKV 213
>U73514-1|AAB68958.1| 261|Homo sapiens short-chain alcohol
dehydrogenase protein.
Length = 261
Score = 93.5 bits (222), Expect = 7e-19
Identities = 70/219 (31%), Positives = 109/219 (49%), Gaps = 14/219 (6%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKY---EAAVQTIKTHTALAPGTNGG 269
V G +A++TG SG+G A + L +GA+ + D EA + + + AP
Sbjct: 8 VKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPA---- 63
Query: 270 EEHSAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGIT--RDNWMLKLSE----EDY 431
DV++ K VQ + ++ + + VN AGI + LK + ED+
Sbjct: 64 --------DVTSEKDVQTALALAKGKFGRVD-VAVNCAGIAVASKTYNLKKGQTHTLEDF 114
Query: 432 DSVLNVNLKGTFLVMQAFAKAMAESSVT-----GSIINISSIVGKYGNMGQTNYASSKAG 596
VL+VNL GTF V++ A M ++ G IIN +S+ G +GQ Y++SK G
Sbjct: 115 QRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGG 174
Query: 597 VVAMTQSAAKELGKFNIRVNAILPGFIDTPIIKTVPDKV 713
+V MT A++L IRV I PG TP++ ++P+KV
Sbjct: 175 IVGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKV 213
>CR456723-1|CAG33004.1| 261|Homo sapiens HADH2 protein.
Length = 261
Score = 93.5 bits (222), Expect = 7e-19
Identities = 70/219 (31%), Positives = 109/219 (49%), Gaps = 14/219 (6%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKY---EAAVQTIKTHTALAPGTNGG 269
V G +A++TG SG+G A + L +GA+ + D EA + + + AP
Sbjct: 8 VKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPA---- 63
Query: 270 EEHSAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGIT--RDNWMLKLSE----EDY 431
DV++ K VQ + ++ + + VN AGI + LK + ED+
Sbjct: 64 --------DVTSEKDVQTALALAKGKFGRVD-VAVNCAGIAVASKTYNLKKGQTHTLEDF 114
Query: 432 DSVLNVNLKGTFLVMQAFAKAMAESSVT-----GSIINISSIVGKYGNMGQTNYASSKAG 596
VL+VNL GTF V++ A M ++ G IIN +S+ G +GQ Y++SK G
Sbjct: 115 QRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGG 174
Query: 597 VVAMTQSAAKELGKFNIRVNAILPGFIDTPIIKTVPDKV 713
+V MT A++L IRV I PG TP++ ++P+KV
Sbjct: 175 IVGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKV 213
>BC000372-1|AAH00372.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 10 protein.
Length = 261
Score = 93.5 bits (222), Expect = 7e-19
Identities = 70/219 (31%), Positives = 109/219 (49%), Gaps = 14/219 (6%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKY---EAAVQTIKTHTALAPGTNGG 269
V G +A++TG SG+G A + L +GA+ + D EA + + + AP
Sbjct: 8 VKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPA---- 63
Query: 270 EEHSAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGIT--RDNWMLKLSE----EDY 431
DV++ K VQ + ++ + + VN AGI + LK + ED+
Sbjct: 64 --------DVTSEKDVQTALALAKGKFGRVD-VAVNCAGIAVASKTYNLKKGQTHTLEDF 114
Query: 432 DSVLNVNLKGTFLVMQAFAKAMAESSVT-----GSIINISSIVGKYGNMGQTNYASSKAG 596
VL+VNL GTF V++ A M ++ G IIN +S+ G +GQ Y++SK G
Sbjct: 115 QRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGG 174
Query: 597 VVAMTQSAAKELGKFNIRVNAILPGFIDTPIIKTVPDKV 713
+V MT A++L IRV I PG TP++ ++P+KV
Sbjct: 175 IVGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKV 213
>AF069134-1|AAC39900.1| 261|Homo sapiens putative short-chain type
dehydrogenase/reductase protein.
Length = 261
Score = 93.5 bits (222), Expect = 7e-19
Identities = 70/219 (31%), Positives = 109/219 (49%), Gaps = 14/219 (6%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKY---EAAVQTIKTHTALAPGTNGG 269
V G +A++TG SG+G A + L +GA+ + D EA + + + AP
Sbjct: 8 VKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPA---- 63
Query: 270 EEHSAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGIT--RDNWMLKLSE----EDY 431
DV++ K VQ + ++ + + VN AGI + LK + ED+
Sbjct: 64 --------DVTSEKDVQTALALAKGKFGRVD-VAVNCAGIAVASKTYNLKKGQTHTLEDF 114
Query: 432 DSVLNVNLKGTFLVMQAFAKAMAESSVT-----GSIINISSIVGKYGNMGQTNYASSKAG 596
VL+VNL GTF V++ A M ++ G IIN +S+ G +GQ Y++SK G
Sbjct: 115 QRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGG 174
Query: 597 VVAMTQSAAKELGKFNIRVNAILPGFIDTPIIKTVPDKV 713
+V MT A++L IRV I PG TP++ ++P+KV
Sbjct: 175 IVGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKV 213
>AF037438-1|AAC16419.1| 261|Homo sapiens 17beta-hydroxysteroid
dehydrogenase type 10/short chain L-3-hydroxyacyl-CoA
deh protein.
Length = 261
Score = 93.5 bits (222), Expect = 7e-19
Identities = 70/219 (31%), Positives = 109/219 (49%), Gaps = 14/219 (6%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKY---EAAVQTIKTHTALAPGTNGG 269
V G +A++TG SG+G A + L +GA+ + D EA + + + AP
Sbjct: 8 VKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPA---- 63
Query: 270 EEHSAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGIT--RDNWMLKLSE----EDY 431
DV++ K VQ + ++ + + VN AGI + LK + ED+
Sbjct: 64 --------DVTSEKDVQTALALAKGKFGRVD-VAVNCAGIAVASKTYNLKKGQTHTLEDF 114
Query: 432 DSVLNVNLKGTFLVMQAFAKAMAESSVT-----GSIINISSIVGKYGNMGQTNYASSKAG 596
VL+VNL GTF V++ A M ++ G IIN +S+ G +GQ Y++SK G
Sbjct: 115 QRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGG 174
Query: 597 VVAMTQSAAKELGKFNIRVNAILPGFIDTPIIKTVPDKV 713
+V MT A++L IRV I PG TP++ ++P+KV
Sbjct: 175 IVGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKV 213
>AF035555-1|AAC15902.1| 261|Homo sapiens 17beta-hydroxysteroid
dehydrogenase type 10/short chain L-3-hydroxyacyl-CoA
deh protein.
Length = 261
Score = 93.5 bits (222), Expect = 7e-19
Identities = 70/219 (31%), Positives = 109/219 (49%), Gaps = 14/219 (6%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKY---EAAVQTIKTHTALAPGTNGG 269
V G +A++TG SG+G A + L +GA+ + D EA + + + AP
Sbjct: 8 VKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPA---- 63
Query: 270 EEHSAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGIT--RDNWMLKLSE----EDY 431
DV++ K VQ + ++ + + VN AGI + LK + ED+
Sbjct: 64 --------DVTSEKDVQTALALAKGKFGRVD-VAVNCAGIAVASKTYNLKKGQTHTLEDF 114
Query: 432 DSVLNVNLKGTFLVMQAFAKAMAESSVT-----GSIINISSIVGKYGNMGQTNYASSKAG 596
VL+VNL GTF V++ A M ++ G IIN +S+ G +GQ Y++SK G
Sbjct: 115 QRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGG 174
Query: 597 VVAMTQSAAKELGKFNIRVNAILPGFIDTPIIKTVPDKV 713
+V MT A++L IRV I PG TP++ ++P+KV
Sbjct: 175 IVGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKV 213
>BC095414-1|AAH95414.1| 245|Homo sapiens 3-hydroxybutyrate
dehydrogenase, type 2 protein.
Length = 245
Score = 91.9 bits (218), Expect = 2e-18
Identities = 61/203 (30%), Positives = 110/203 (54%), Gaps = 2/203 (0%)
Frame = +3
Query: 93 GLVVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGE 272
G + G++ ++T A GIG+AA ++EGA VIA D E+ +Q ++ + PG
Sbjct: 2 GRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDIN-ESKLQELEKY----PGIQ--- 53
Query: 273 EHSAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVN 452
LDV+ K + + + ++ N AG +L E+D+D +N+N
Sbjct: 54 ---TRVLDVTKKKQIDQFANEVERLD-----VLFNVAGFVHHGTVLDCEEKDWDFSMNLN 105
Query: 453 LKGTFLVMQAFA-KAMAESSVTGSIINISSIVGKY-GNMGQTNYASSKAGVVAMTQSAAK 626
++ +L+++AF K +A+ S G+IIN+SS+ G + + Y+++KA V+ +T+S A
Sbjct: 106 VRSMYLMIKAFLPKMLAQKS--GNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAA 163
Query: 627 ELGKFNIRVNAILPGFIDTPIIK 695
+ + IR N + PG +DTP ++
Sbjct: 164 DFIQQGIRCNCVCPGTVDTPSLQ 186
>BC001953-1|AAH01953.1| 245|Homo sapiens 3-hydroxybutyrate
dehydrogenase, type 2 protein.
Length = 245
Score = 91.9 bits (218), Expect = 2e-18
Identities = 61/203 (30%), Positives = 110/203 (54%), Gaps = 2/203 (0%)
Frame = +3
Query: 93 GLVVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGE 272
G + G++ ++T A GIG+AA ++EGA VIA D E+ +Q ++ + PG
Sbjct: 2 GRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDIN-ESKLQELEKY----PGIQ--- 53
Query: 273 EHSAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVN 452
LDV+ K + + + ++ N AG +L E+D+D +N+N
Sbjct: 54 ---TRVLDVTKKKQIDQFASEVERLD-----VLFNVAGFVHHGTVLDCEEKDWDFSMNLN 105
Query: 453 LKGTFLVMQAFA-KAMAESSVTGSIINISSIVGKY-GNMGQTNYASSKAGVVAMTQSAAK 626
++ +L+++AF K +A+ S G+IIN+SS+ G + + Y+++KA V+ +T+S A
Sbjct: 106 VRSMYLMIKAFLPKMLAQKS--GNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAA 163
Query: 627 ELGKFNIRVNAILPGFIDTPIIK 695
+ + IR N + PG +DTP ++
Sbjct: 164 DFIQQGIRCNCVCPGTVDTPSLQ 186
>AF164790-1|AAF80754.1| 245|Homo sapiens oxidoreductase UCPA
protein.
Length = 245
Score = 91.9 bits (218), Expect = 2e-18
Identities = 61/203 (30%), Positives = 110/203 (54%), Gaps = 2/203 (0%)
Frame = +3
Query: 93 GLVVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGE 272
G + G++ ++T A GIG+AA ++EGA VIA D E+ +Q ++ + PG
Sbjct: 2 GRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDIN-ESKLQELEKY----PGIQ--- 53
Query: 273 EHSAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVN 452
LDV+ K + + + ++ N AG +L E+D+D +N+N
Sbjct: 54 ---TRVLDVTKKKQIDQFANEVERLD-----VLFNVAGFVHHGTVLDCEEKDWDFSMNLN 105
Query: 453 LKGTFLVMQAFA-KAMAESSVTGSIINISSIVGKY-GNMGQTNYASSKAGVVAMTQSAAK 626
++ +L+++AF K +A+ S G+IIN+SS+ G + + Y+++KA V+ +T+S A
Sbjct: 106 VRSMYLMIKAFLPKMLAQKS--GNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAA 163
Query: 627 ELGKFNIRVNAILPGFIDTPIIK 695
+ + IR N + PG +DTP ++
Sbjct: 164 DFIQQGIRCNCVCPGTVDTPSLQ 186
>U78302-1|AAB88724.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase
protein.
Length = 335
Score = 91.5 bits (217), Expect = 3e-18
Identities = 59/193 (30%), Positives = 100/193 (51%)
Frame = +3
Query: 105 GRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHSA 284
G++A +TG G+G+G+ +LS GA + A RK + +K G + H A
Sbjct: 59 GKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDV----LKATAEQISSQTGNKVH-A 113
Query: 285 VELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLKGT 464
++ DV + VQ+ V + +K P +I N+AG + +LS + ++ ++ L GT
Sbjct: 114 IQCDVRDPDMVQNTVSELIKVAGHPNIVINNAAG-NFISPTERLSPNAWKTITDIVLNGT 172
Query: 465 FLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELGKFN 644
V K + ++ + ++I++I + G+ AS+KAGV AM++S A E GK+
Sbjct: 173 AFVTLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLAAEWGKYG 232
Query: 645 IRVNAILPGFIDT 683
+R N I PG I T
Sbjct: 233 MRFNVIQPGPIKT 245
>U49352-1|AAB09423.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase
protein.
Length = 335
Score = 91.5 bits (217), Expect = 3e-18
Identities = 59/193 (30%), Positives = 100/193 (51%)
Frame = +3
Query: 105 GRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHSA 284
G++A +TG G+G+G+ +LS GA + A RK + +K G + H A
Sbjct: 59 GKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDV----LKATAEQISSQTGNKVH-A 113
Query: 285 VELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLKGT 464
++ DV + VQ+ V + +K P +I N+AG + +LS + ++ ++ L GT
Sbjct: 114 IQCDVRDPDMVQNTVSELIKVAGHPNIVINNAAG-NFISPTERLSPNAWKTITDIVLNGT 172
Query: 465 FLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELGKFN 644
V K + ++ + ++I++I + G+ AS+KAGV AM++S A E GK+
Sbjct: 173 AFVTLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLAAEWGKYG 232
Query: 645 IRVNAILPGFIDT 683
+R N I PG I T
Sbjct: 233 MRFNVIQPGPIKT 245
>L76465-1|AAA89175.1| 266|Homo sapiens NAD+-dependent
15-hydroxyprostaglandin dehydrogenase protein.
Length = 266
Score = 91.5 bits (217), Expect = 3e-18
Identities = 67/208 (32%), Positives = 109/208 (52%), Gaps = 7/208 (3%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQ-TIKTHTALAPGTNGGEE 275
V G++ALVTGA GIGRA + L +GA V D EA VQ H P ++
Sbjct: 3 VNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALHEQFEP-----QK 57
Query: 276 HSAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNL 455
++ DV++ + ++D + + + + I+VN+AG+ +E++++ L +NL
Sbjct: 58 TLFIQCDVADQQQLRDTFRKVVDHFGRLD-ILVNNAGVN--------NEKNWEKTLQINL 108
Query: 456 ----KGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAA 623
GT+L + +K G IIN+SS+ G Q Y +SK G+V T+SAA
Sbjct: 109 VSVISGTYLGLDYMSK--QNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAA 166
Query: 624 KELGKFN--IRVNAILPGFIDTPIIKTV 701
N +R+NAI PGF++T I++++
Sbjct: 167 LAANLMNSGVRLNAICPGFVNTAILESI 194
>L26050-1|AAA67551.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase
protein.
Length = 335
Score = 91.5 bits (217), Expect = 3e-18
Identities = 59/193 (30%), Positives = 100/193 (51%)
Frame = +3
Query: 105 GRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHSA 284
G++A +TG G+G+G+ +LS GA + A RK + +K G + H A
Sbjct: 59 GKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDV----LKATAEQISSQTGNKVH-A 113
Query: 285 VELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLKGT 464
++ DV + VQ+ V + +K P +I N+AG + +LS + ++ ++ L GT
Sbjct: 114 IQCDVRDPDMVQNTVSELIKVAGHPNIVINNAAG-NFISPTERLSPNAWKTITDIVLNGT 172
Query: 465 FLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELGKFN 644
V K + ++ + ++I++I + G+ AS+KAGV AM++S A E GK+
Sbjct: 173 AFVTLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLAAEWGKYG 232
Query: 645 IRVNAILPGFIDT 683
+R N I PG I T
Sbjct: 233 MRFNVIQPGPIKT 245
>J05594-1|AAA89174.1| 266|Homo sapiens NAD+-dependent
15-hydroxyprostaglandin dehydrogenase protein.
Length = 266
Score = 91.5 bits (217), Expect = 3e-18
Identities = 67/208 (32%), Positives = 109/208 (52%), Gaps = 7/208 (3%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQ-TIKTHTALAPGTNGGEE 275
V G++ALVTGA GIGRA + L +GA V D EA VQ H P ++
Sbjct: 3 VNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALHEQFEP-----QK 57
Query: 276 HSAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNL 455
++ DV++ + ++D + + + + I+VN+AG+ +E++++ L +NL
Sbjct: 58 TLFIQCDVADQQQLRDTFRKVVDHFGRLD-ILVNNAGVN--------NEKNWEKTLQINL 108
Query: 456 ----KGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAA 623
GT+L + +K G IIN+SS+ G Q Y +SK G+V T+SAA
Sbjct: 109 VSVISGTYLGLDYMSK--QNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAA 166
Query: 624 KELGKFN--IRVNAILPGFIDTPIIKTV 701
N +R+NAI PGF++T I++++
Sbjct: 167 LAANLMNSGVRLNAICPGFVNTAILESI 194
>BC105082-1|AAI05083.1| 335|Homo sapiens 2,4-dienoyl CoA reductase
1, mitochondrial protein.
Length = 335
Score = 91.5 bits (217), Expect = 3e-18
Identities = 59/193 (30%), Positives = 100/193 (51%)
Frame = +3
Query: 105 GRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHSA 284
G++A +TG G+G+G+ +LS GA + A RK + +K G + H A
Sbjct: 59 GKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDV----LKATAEQISSQTGNKVH-A 113
Query: 285 VELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLKGT 464
++ DV + VQ+ V + +K P +I N+AG + +LS + ++ ++ L GT
Sbjct: 114 IQCDVRDPDMVQNTVSELIKVAGHPNIVINNAAG-NFISPTERLSPNAWKTITDIVLNGT 172
Query: 465 FLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELGKFN 644
V K + ++ + ++I++I + G+ AS+KAGV AM++S A E GK+
Sbjct: 173 AFVTLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLAAEWGKYG 232
Query: 645 IRVNAILPGFIDT 683
+R N I PG I T
Sbjct: 233 MRFNVIQPGPIKT 245
>BC105080-1|AAI05081.1| 335|Homo sapiens 2,4-dienoyl CoA reductase
1, mitochondrial protein.
Length = 335
Score = 91.5 bits (217), Expect = 3e-18
Identities = 59/193 (30%), Positives = 100/193 (51%)
Frame = +3
Query: 105 GRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHSA 284
G++A +TG G+G+G+ +LS GA + A RK + +K G + H A
Sbjct: 59 GKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDV----LKATAEQISSQTGNKVH-A 113
Query: 285 VELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLKGT 464
++ DV + VQ+ V + +K P +I N+AG + +LS + ++ ++ L GT
Sbjct: 114 IQCDVRDPDMVQNTVSELIKVAGHPNIVINNAAG-NFISPTERLSPNAWKTITDIVLNGT 172
Query: 465 FLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELGKFN 644
V K + ++ + ++I++I + G+ AS+KAGV AM++S A E GK+
Sbjct: 173 AFVTLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLAAEWGKYG 232
Query: 645 IRVNAILPGFIDT 683
+R N I PG I T
Sbjct: 233 MRFNVIQPGPIKT 245
>AY358841-1|AAQ89200.1| 245|Homo sapiens GRLD6308 protein.
Length = 245
Score = 91.5 bits (217), Expect = 3e-18
Identities = 61/203 (30%), Positives = 110/203 (54%), Gaps = 2/203 (0%)
Frame = +3
Query: 93 GLVVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGE 272
G + G++ ++T A GIG+AA ++EGA VIA D E+ +Q ++ + PG
Sbjct: 2 GRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDIN-ESKLQELEKY----PGIQ--- 53
Query: 273 EHSAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVN 452
LDV+ K + + + ++ N AG +L E+D+D +N+N
Sbjct: 54 ---TRVLDVTKKKQIDQFASEVERLD-----VLFNVAGFVHHGTVLDCEEKDWDFSMNLN 105
Query: 453 LKGTFLVMQAFA-KAMAESSVTGSIINISSIVGKY-GNMGQTNYASSKAGVVAMTQSAAK 626
++ +L+++AF K +A+ S G+IIN+SS+ G + + Y+++KA V+ +T+S A
Sbjct: 106 VRSMYLMIKAFLPKMLAQKS--GNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSLAA 163
Query: 627 ELGKFNIRVNAILPGFIDTPIIK 695
+ + IR N + PG +DTP ++
Sbjct: 164 DFIQQGIRCNCVCPGTVDTPSLQ 186
>AC004612-1|AAC14671.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase
precursor protein.
Length = 335
Score = 91.5 bits (217), Expect = 3e-18
Identities = 59/193 (30%), Positives = 100/193 (51%)
Frame = +3
Query: 105 GRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHSA 284
G++A +TG G+G+G+ +LS GA + A RK + +K G + H A
Sbjct: 59 GKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDV----LKATAEQISSQTGNKVH-A 113
Query: 285 VELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLKGT 464
++ DV + VQ+ V + +K P +I N+AG + +LS + ++ ++ L GT
Sbjct: 114 IQCDVRDPDMVQNTVSELIKVAGHPNIVINNAAG-NFISPTERLSPNAWKTITDIVLNGT 172
Query: 465 FLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELGKFN 644
V K + ++ + ++I++I + G+ AS+KAGV AM++S A E GK+
Sbjct: 173 AFVTLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLAAEWGKYG 232
Query: 645 IRVNAILPGFIDT 683
+R N I PG I T
Sbjct: 233 MRFNVIQPGPIKT 245
>DQ903072-1|ABI75347.1| 266|Homo sapiens hydroxyprostaglandin
dehydrogenase 15-(NAD) protein.
Length = 266
Score = 89.0 bits (211), Expect = 2e-17
Identities = 66/207 (31%), Positives = 108/207 (52%), Gaps = 6/207 (2%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEH 278
V G++ALVTGA GIGRA + L +GA V D EA VQ A ++
Sbjct: 3 VNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQC----KAALDEQFEPQKT 58
Query: 279 SAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNL- 455
++ DV++ + ++D + + + + I+VN+AG+ +E++++ L +NL
Sbjct: 59 LFIQCDVADQQQLRDTFRKVVDHFGRLD-ILVNNAGVN--------NEKNWEKTLQINLV 109
Query: 456 ---KGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAK 626
GT+L + +K G IIN+SS+ G Q Y +SK G+V T+SAA
Sbjct: 110 SVISGTYLGLDYMSK--QNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAAL 167
Query: 627 ELGKFN--IRVNAILPGFIDTPIIKTV 701
N +R+NAI PGF++T I++++
Sbjct: 168 AANLMNSGVRLNAICPGFVNTAILESI 194
>BC018986-1|AAH18986.1| 266|Homo sapiens hydroxyprostaglandin
dehydrogenase 15-(NAD) protein.
Length = 266
Score = 89.0 bits (211), Expect = 2e-17
Identities = 66/207 (31%), Positives = 108/207 (52%), Gaps = 6/207 (2%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEH 278
V G++ALVTGA GIGRA + L +GA V D EA VQ A ++
Sbjct: 3 VNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQC----KAALDEQFEPQKT 58
Query: 279 SAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNL- 455
++ DV++ + ++D + + + + I+VN+AG+ +E++++ L +NL
Sbjct: 59 LFIQCDVADQQQLRDTFRKVVDHFGRLD-ILVNNAGVN--------NEKNWEKTLQINLV 109
Query: 456 ---KGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAK 626
GT+L + +K G IIN+SS+ G Q Y +SK G+V T+SAA
Sbjct: 110 SVISGTYLGLDYMSK--QNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAAL 167
Query: 627 ELGKFN--IRVNAILPGFIDTPIIKTV 701
N +R+NAI PGF++T I++++
Sbjct: 168 AANLMNSGVRLNAICPGFVNTAILESI 194
>BC006294-1|AAH06294.1| 270|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 14 protein.
Length = 270
Score = 86.6 bits (205), Expect = 8e-17
Identities = 56/195 (28%), Positives = 98/195 (50%)
Frame = +3
Query: 105 GRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHSA 284
G++ +VTG G GIG + GA V+ D K E+ + ++ PG
Sbjct: 9 GKVVVVTGGGRGIGAGIVRAFVNSGARVVICD-KDESGGRALEQEL---PGA------VF 58
Query: 285 VELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLKGT 464
+ DV+ V+ LV +T++++ + C++ N+ + S + + +L +NL GT
Sbjct: 59 ILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGT 118
Query: 465 FLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELGKFN 644
+ + + + +S G++INISS+VG G Y ++K V AMT++ A + +
Sbjct: 119 YTLTKLALPYLRKSQ--GNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYG 176
Query: 645 IRVNAILPGFIDTPI 689
+RVN I PG I TP+
Sbjct: 177 VRVNCISPGNIWTPL 191
>BC006283-1|AAH06283.1| 270|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 14 protein.
Length = 270
Score = 86.6 bits (205), Expect = 8e-17
Identities = 56/195 (28%), Positives = 98/195 (50%)
Frame = +3
Query: 105 GRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHSA 284
G++ +VTG G GIG + GA V+ D K E+ + ++ PG
Sbjct: 9 GKVVVVTGGGRGIGAGIVRAFVNSGARVVICD-KDESGGRALEQEL---PGA------VF 58
Query: 285 VELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLKGT 464
+ DV+ V+ LV +T++++ + C++ N+ + S + + +L +NL GT
Sbjct: 59 ILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGT 118
Query: 465 FLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELGKFN 644
+ + + + +S G++INISS+VG G Y ++K V AMT++ A + +
Sbjct: 119 YTLTKLALPYLRKSQ--GNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYG 176
Query: 645 IRVNAILPGFIDTPI 689
+RVN I PG I TP+
Sbjct: 177 VRVNCISPGNIWTPL 191
>AY358430-1|AAQ88796.1| 270|Homo sapiens ATGT502 protein.
Length = 270
Score = 86.6 bits (205), Expect = 8e-17
Identities = 56/195 (28%), Positives = 98/195 (50%)
Frame = +3
Query: 105 GRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHSA 284
G++ +VTG G GIG + GA V+ D K E+ + ++ PG
Sbjct: 9 GKVVVVTGGGRGIGAGIVRAFVNSGARVVICD-KDESGGRALEQEL---PGA------VF 58
Query: 285 VELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLKGT 464
+ DV+ V+ LV +T++++ + C++ N+ + S + + +L +NL GT
Sbjct: 59 ILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGT 118
Query: 465 FLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELGKFN 644
+ + + + +S G++INISS+VG G Y ++K V AMT++ A + +
Sbjct: 119 YTLTKLALPYLRKSQ--GNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYG 176
Query: 645 IRVNAILPGFIDTPI 689
+RVN I PG I TP+
Sbjct: 177 VRVNCISPGNIWTPL 191
>AF126781-1|AAF06940.1| 270|Homo sapiens retinal short-chain
dehydrogenase/reductase retSDR3 protein.
Length = 270
Score = 86.6 bits (205), Expect = 8e-17
Identities = 56/195 (28%), Positives = 98/195 (50%)
Frame = +3
Query: 105 GRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHSA 284
G++ +VTG G GIG + GA V+ D K E+ + ++ PG
Sbjct: 9 GKVVVVTGGGRGIGAGIVRAFVNSGARVVICD-KDESGGRALEQEL---PGA------VF 58
Query: 285 VELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLKGT 464
+ DV+ V+ LV +T++++ + C++ N+ + S + + +L +NL GT
Sbjct: 59 ILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGT 118
Query: 465 FLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELGKFN 644
+ + + + +S G++INISS+VG G Y ++K V AMT++ A + +
Sbjct: 119 YTLTKLALPYLRKSQ--GNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYG 176
Query: 645 IRVNAILPGFIDTPI 689
+RVN I PG I TP+
Sbjct: 177 VRVNCISPGNIWTPL 191
>BC002529-1|AAH02529.1| 303|Homo sapiens peroxisomal
trans-2-enoyl-CoA reductase protein.
Length = 303
Score = 83.8 bits (198), Expect = 6e-16
Identities = 62/199 (31%), Positives = 102/199 (51%), Gaps = 1/199 (0%)
Frame = +3
Query: 84 MVSGLVVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTN 263
+ GL+ G++A+VTG +GIG+A + L + G+ V+ A RK E A P T
Sbjct: 11 LAPGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTK 70
Query: 264 GGEEHSAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVL 443
++ ++ N + V +LV+ TL + K +VN+ G + +S + + +VL
Sbjct: 71 QARV-IPIQCNIRNEEEVNNLVKSTLDTFGKIN-FLVNNGGGQFLSPAEHISSKGWHAVL 128
Query: 444 NVNLKGTFLVMQA-FAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSA 620
NL GTF + +A ++ M E GSI+NI + K G + +++AGV +T+S
Sbjct: 129 ETNLTGTFYMCKAVYSSWMKEHG--GSIVNI-IVPTKAGFPLAVHSGAARAGVYNLTKSL 185
Query: 621 AKELGKFNIRVNAILPGFI 677
A E IR+N + PG I
Sbjct: 186 ALEWACSGIRINCVAPGVI 204
>AF232009-1|AAF69798.1| 303|Homo sapiens peroxisomal trans 2-enoyl
CoA reductase protein.
Length = 303
Score = 83.8 bits (198), Expect = 6e-16
Identities = 62/199 (31%), Positives = 102/199 (51%), Gaps = 1/199 (0%)
Frame = +3
Query: 84 MVSGLVVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTN 263
+ GL+ G++A+VTG +GIG+A + L + G+ V+ A RK E A P T
Sbjct: 11 LAPGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTK 70
Query: 264 GGEEHSAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVL 443
++ ++ N + V +LV+ TL + K +VN+ G + +S + + +VL
Sbjct: 71 QARV-IPIQCNIRNEEEVNNLVKSTLDTFGKIN-FLVNNGGGQFLSPAEHISSKGWHAVL 128
Query: 444 NVNLKGTFLVMQA-FAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSA 620
NL GTF + +A ++ M E GSI+NI + K G + +++AGV +T+S
Sbjct: 129 ETNLTGTFYMCKAVYSSWMKEHG--GSIVNI-IVPTKAGFPLAVHSGAARAGVYNLTKSL 185
Query: 621 AKELGKFNIRVNAILPGFI 677
A E IR+N + PG I
Sbjct: 186 ALEWACSGIRINCVAPGVI 204
>AF212234-1|AAK14920.1| 322|Homo sapiens HPDHase protein.
Length = 322
Score = 83.8 bits (198), Expect = 6e-16
Identities = 62/199 (31%), Positives = 102/199 (51%), Gaps = 1/199 (0%)
Frame = +3
Query: 84 MVSGLVVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTN 263
+ GL+ G++A+VTG +GIG+A + L + G+ V+ A RK E A P T
Sbjct: 30 LAPGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTK 89
Query: 264 GGEEHSAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVL 443
++ ++ N + V +LV+ TL + K +VN+ G + +S + + +VL
Sbjct: 90 QARV-IPIQCNIRNEEEVNNLVKSTLDTFGKIN-FLVNNGGGQFLSPAEHISSKGWHAVL 147
Query: 444 NVNLKGTFLVMQA-FAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSA 620
NL GTF + +A ++ M E GSI+NI + K G + +++AGV +T+S
Sbjct: 148 ETNLTGTFYMCKAVYSSWMKEHG--GSIVNI-IVPTKAGFPLAVHSGAARAGVYNLTKSL 204
Query: 621 AKELGKFNIRVNAILPGFI 677
A E IR+N + PG I
Sbjct: 205 ALEWACSGIRINCVAPGVI 223
>AC010686-2|AAY14657.1| 303|Homo sapiens unknown protein.
Length = 303
Score = 83.8 bits (198), Expect = 6e-16
Identities = 62/199 (31%), Positives = 102/199 (51%), Gaps = 1/199 (0%)
Frame = +3
Query: 84 MVSGLVVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTN 263
+ GL+ G++A+VTG +GIG+A + L + G+ V+ A RK E A P T
Sbjct: 11 LAPGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTK 70
Query: 264 GGEEHSAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVL 443
++ ++ N + V +LV+ TL + K +VN+ G + +S + + +VL
Sbjct: 71 QARV-IPIQCNIRNEEEVNNLVKSTLDTFGKIN-FLVNNGGGQFLSPAEHISSKGWHAVL 128
Query: 444 NVNLKGTFLVMQA-FAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSA 620
NL GTF + +A ++ M E GSI+NI + K G + +++AGV +T+S
Sbjct: 129 ETNLTGTFYMCKAVYSSWMKEHG--GSIVNI-IVPTKAGFPLAVHSGAARAGVYNLTKSL 185
Query: 621 AKELGKFNIRVNAILPGFI 677
A E IR+N + PG I
Sbjct: 186 ALEWACSGIRINCVAPGVI 204
>BT006881-1|AAP35527.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 81.4 bits (192), Expect = 3e-15
Identities = 57/195 (29%), Positives = 91/195 (46%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEH 278
+ GR LVTGAG GIGR Q L GA V+A R ++ + P
Sbjct: 5 LAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPGIEP-------- 56
Query: 279 SAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLK 458
V +D+ + +A + + P ++VN+A + L++++E +D VNL+
Sbjct: 57 --VCVDLGDWEATERALGSV-----GPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLR 109
Query: 459 GTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELGK 638
V Q A+ + V G+I+N+SS + + Y S+K + +T+ A ELG
Sbjct: 110 AVIQVSQIVARGLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGP 169
Query: 639 FNIRVNAILPGFIDT 683
IRVNA+ P + T
Sbjct: 170 HKIRVNAVNPTVVMT 184
>BC003018-1|AAH03018.1| 243|Homo sapiens Unknown (protein for
IMAGE:2822726) protein.
Length = 243
Score = 81.4 bits (192), Expect = 3e-15
Identities = 57/195 (29%), Positives = 91/195 (46%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEH 278
+ GR LVTGAG GIGR Q L GA V+A R ++ + P
Sbjct: 4 LAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPGIEP-------- 55
Query: 279 SAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLK 458
V +D+ + +A + + P ++VN+A + L++++E +D VNL+
Sbjct: 56 --VCVDLGDWEATERALGSV-----GPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLR 108
Query: 459 GTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELGK 638
V Q A+ + V G+I+N+SS + + Y S+K + +T+ A ELG
Sbjct: 109 AVIQVSQIVARGLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGP 168
Query: 639 FNIRVNAILPGFIDT 683
IRVNA+ P + T
Sbjct: 169 HKIRVNAVNPTVVMT 183
>BC001470-1|AAH01470.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 81.4 bits (192), Expect = 3e-15
Identities = 57/195 (29%), Positives = 91/195 (46%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEH 278
+ GR LVTGAG GIGR Q L GA V+A R ++ + P
Sbjct: 5 LAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPGIEP-------- 56
Query: 279 SAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLK 458
V +D+ + +A + + P ++VN+A + L++++E +D VNL+
Sbjct: 57 --VCVDLGDWEATERALGSV-----GPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLR 109
Query: 459 GTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELGK 638
V Q A+ + V G+I+N+SS + + Y S+K + +T+ A ELG
Sbjct: 110 AVIQVSQIVARGLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGP 169
Query: 639 FNIRVNAILPGFIDT 683
IRVNA+ P + T
Sbjct: 170 HKIRVNAVNPTVVMT 184
>AJ250303-1|CAB89810.1| 303|Homo sapiens peroxisomal 2-enoyl-CoA
reductase protein.
Length = 303
Score = 81.4 bits (192), Expect = 3e-15
Identities = 61/199 (30%), Positives = 101/199 (50%), Gaps = 1/199 (0%)
Frame = +3
Query: 84 MVSGLVVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTN 263
+ GL+ G++A VTG +GIG+A + L + G+ V+ A RK E A P T
Sbjct: 11 LAPGLLQGQVAFVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTK 70
Query: 264 GGEEHSAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVL 443
++ ++ N + V +LV+ TL + K +VN+ G + +S + + +VL
Sbjct: 71 QARV-IPIQCNIRNEEEVNNLVKSTLDTFGKIN-FLVNNGGGQFLSPAEHISSKGWHAVL 128
Query: 444 NVNLKGTFLVMQA-FAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSA 620
NL G+F + +A ++ M E GSI+NI + K G + +++AGV +T+S
Sbjct: 129 RTNLTGSFYMCKAVYSSWMKEHG--GSIVNI-IVPTKAGFPLAVHSGAARAGVYNLTKSL 185
Query: 621 AKELGKFNIRVNAILPGFI 677
A E IR+N + PG I
Sbjct: 186 ALEWACSGIRINCVAPGVI 204
>AF515625-1|AAM54026.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 81.4 bits (192), Expect = 3e-15
Identities = 57/195 (29%), Positives = 91/195 (46%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEH 278
+ GR LVTGAG GIGR Q L GA V+A R ++ + P
Sbjct: 5 LAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPGIEP-------- 56
Query: 279 SAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLK 458
V +D+ + +A + + P ++VN+A + L++++E +D VNL+
Sbjct: 57 --VCVDLGDWEATERALGSV-----GPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLR 109
Query: 459 GTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELGK 638
V Q A+ + V G+I+N+SS + + Y S+K + +T+ A ELG
Sbjct: 110 AVIQVSQIVARGLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGP 169
Query: 639 FNIRVNAILPGFIDT 683
IRVNA+ P + T
Sbjct: 170 HKIRVNAVNPTVVMT 184
>AF515624-1|AAO15991.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 81.4 bits (192), Expect = 3e-15
Identities = 57/195 (29%), Positives = 91/195 (46%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEH 278
+ GR LVTGAG GIGR Q L GA V+A R ++ + P
Sbjct: 5 LAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPGIEP-------- 56
Query: 279 SAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLK 458
V +D+ + +A + + P ++VN+A + L++++E +D VNL+
Sbjct: 57 --VCVDLGDWEATERALGSV-----GPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLR 109
Query: 459 GTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELGK 638
V Q A+ + V G+I+N+SS + + Y S+K + +T+ A ELG
Sbjct: 110 AVIQVSQIVARGLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGP 169
Query: 639 FNIRVNAILPGFIDT 683
IRVNA+ P + T
Sbjct: 170 HKIRVNAVNPTVVMT 184
>AF515623-1|AAN59786.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 81.4 bits (192), Expect = 3e-15
Identities = 57/195 (29%), Positives = 91/195 (46%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEH 278
+ GR LVTGAG GIGR Q L GA V+A R ++ + P
Sbjct: 5 LAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPGIEP-------- 56
Query: 279 SAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLK 458
V +D+ + +A + + P ++VN+A + L++++E +D VNL+
Sbjct: 57 --VCVDLGDWEATERALGSV-----GPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLR 109
Query: 459 GTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELGK 638
V Q A+ + V G+I+N+SS + + Y S+K + +T+ A ELG
Sbjct: 110 AVIQVSQIVARGLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGP 169
Query: 639 FNIRVNAILPGFIDT 683
IRVNA+ P + T
Sbjct: 170 HKIRVNAVNPTVVMT 184
>AF113123-1|AAF14864.1| 244|Homo sapiens carbonyl reductase
protein.
Length = 244
Score = 81.4 bits (192), Expect = 3e-15
Identities = 57/195 (29%), Positives = 91/195 (46%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEH 278
+ GR LVTGAG GIGR Q L GA V+A R ++ + P
Sbjct: 5 LAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPGIEP-------- 56
Query: 279 SAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLK 458
V +D+ + +A + + P ++VN+A + L++++E +D VNL+
Sbjct: 57 --VCVDLGDWEATERALGSV-----GPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLR 109
Query: 459 GTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELGK 638
V Q A+ + V G+I+N+SS + + Y S+K + +T+ A ELG
Sbjct: 110 AVIQVSQIVARGLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGP 169
Query: 639 FNIRVNAILPGFIDT 683
IRVNA+ P + T
Sbjct: 170 HKIRVNAVNPTVVMT 184
>AB013846-1|BAB64299.1| 244|Homo sapiens kidney dicarbonyl
reductase protein.
Length = 244
Score = 81.4 bits (192), Expect = 3e-15
Identities = 57/195 (29%), Positives = 91/195 (46%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEH 278
+ GR LVTGAG GIGR Q L GA V+A R ++ + P
Sbjct: 5 LAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPGIEP-------- 56
Query: 279 SAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLK 458
V +D+ + +A + + P ++VN+A + L++++E +D VNL+
Sbjct: 57 --VCVDLGDWEATERALGSV-----GPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLR 109
Query: 459 GTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELGK 638
V Q A+ + V G+I+N+SS + + Y S+K + +T+ A ELG
Sbjct: 110 AVIQVSQIVARGLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGP 169
Query: 639 FNIRVNAILPGFIDT 683
IRVNA+ P + T
Sbjct: 170 HKIRVNAVNPTVVMT 184
>AY092415-1|AAM18189.1| 196|Homo sapiens endoplasmic
reticulum-associated amyloid beta peptide-binding
protein protein.
Length = 196
Score = 81.0 bits (191), Expect = 4e-15
Identities = 53/151 (35%), Positives = 81/151 (53%), Gaps = 11/151 (7%)
Frame = +3
Query: 294 DVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGIT--RDNWMLKLSE----EDYDSVLNVNL 455
DV++ K VQ + ++ + + VN AGI + LK + ED+ VL+VNL
Sbjct: 14 DVTSEKDVQTALALAKGKFGRVD-VAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 72
Query: 456 KGTFLVMQAFAKAMAESSVT-----GSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSA 620
GTF V++ A M ++ G IIN +S+ G +GQ Y++SK G+V MT
Sbjct: 73 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 132
Query: 621 AKELGKFNIRVNAILPGFIDTPIIKTVPDKV 713
A++L IRV I PG TP++ ++P+KV
Sbjct: 133 ARDLAPIGIRVMTIAPGLFGTPLLTSLPEKV 163
>AF139841-1|AAP97273.1| 244|Homo sapiens carbonyl reductase II
protein.
Length = 244
Score = 81.0 bits (191), Expect = 4e-15
Identities = 57/195 (29%), Positives = 91/195 (46%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEH 278
+ GR LVTGAG GIGR Q L GA V+A R ++ + P
Sbjct: 5 LAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPGIEP-------- 56
Query: 279 SAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLK 458
V +D+ + +A + + P ++VN+A + L++++E +D VNL+
Sbjct: 57 --VCVDLGDWEATERALGSV-----GPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLR 109
Query: 459 GTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELGK 638
V Q A+ + V G+I+N+SS + + Y S+K + +T+ A ELG
Sbjct: 110 AVIQVSQIAARGLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGP 169
Query: 639 FNIRVNAILPGFIDT 683
IRVNA+ P + T
Sbjct: 170 HKIRVNAVNPTVVMT 184
>DQ344810-1|ABD75823.1| 278|Homo sapiens NADP(H)-dependent retinol
dehydrogenase/reductase short isoform protein.
Length = 278
Score = 80.6 bits (190), Expect = 5e-15
Identities = 60/208 (28%), Positives = 103/208 (49%), Gaps = 1/208 (0%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEH 278
+ ++ALVT + GIG A + L+++GA V+ + RK + Q + T G H
Sbjct: 30 LANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCH 89
Query: 279 SAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLK 458
V ++ + LV +K + ++ N+A ++ ++EE +D L++N+K
Sbjct: 90 ------VGKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVK 143
Query: 459 GTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELGK 638
L+ +A M E GS++ +SSI + G + Y SK ++ +T++ A EL
Sbjct: 144 APALMTKAVVPEM-EKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAP 202
Query: 639 FNIRVNAILPGFIDTPIIKTV-PDKVKE 719
NIRVN + PG I T + + DK KE
Sbjct: 203 RNIRVNCLAPGLIKTSFSRMLWMDKEKE 230
>BC003019-1|AAH03019.1| 278|Homo sapiens dehydrogenase/reductase
(SDR family) member 4 protein.
Length = 278
Score = 80.6 bits (190), Expect = 5e-15
Identities = 60/208 (28%), Positives = 103/208 (49%), Gaps = 1/208 (0%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEH 278
+ ++ALVT + GIG A + L+++GA V+ + RK + Q + T G H
Sbjct: 30 LANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCH 89
Query: 279 SAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLK 458
V ++ + LV +K + ++ N+A ++ ++EE +D L++N+K
Sbjct: 90 ------VGKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVK 143
Query: 459 GTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELGK 638
L+ +A M E GS++ +SSI + G + Y SK ++ +T++ A EL
Sbjct: 144 APALMTKAVVPEM-EKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAP 202
Query: 639 FNIRVNAILPGFIDTPIIKTV-PDKVKE 719
NIRVN + PG I T + + DK KE
Sbjct: 203 RNIRVNCLAPGLIKTSFSRMLWMDKEKE 230
>AY358638-1|AAQ89001.1| 278|Homo sapiens SCAD-SRL protein.
Length = 278
Score = 80.6 bits (190), Expect = 5e-15
Identities = 60/208 (28%), Positives = 103/208 (49%), Gaps = 1/208 (0%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEH 278
+ ++ALVT + GIG A + L+++GA V+ + RK + Q + T G H
Sbjct: 30 LANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCH 89
Query: 279 SAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLK 458
V ++ + LV +K + ++ N+A ++ ++EE +D L++N+K
Sbjct: 90 ------VGKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVK 143
Query: 459 GTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELGK 638
L+ +A M E GS++ +SSI + G + Y SK ++ +T++ A EL
Sbjct: 144 APALMTKAVVPEM-EKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAP 202
Query: 639 FNIRVNAILPGFIDTPIIKTV-PDKVKE 719
NIRVN + PG I T + + DK KE
Sbjct: 203 RNIRVNCLAPGLIKTSFSRMLWMDKEKE 230
>AB045131-1|BAB18775.1| 260|Homo sapiens NADPH-dependent retinol
dehydrogenase/reductase protein.
Length = 260
Score = 80.6 bits (190), Expect = 5e-15
Identities = 60/208 (28%), Positives = 103/208 (49%), Gaps = 1/208 (0%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEH 278
+ ++ALVT + GIG A + L+++GA V+ + RK + Q + T G H
Sbjct: 12 LANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCH 71
Query: 279 SAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLK 458
V ++ + LV +K + ++ N+A ++ ++EE +D L++N+K
Sbjct: 72 ------VGKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVK 125
Query: 459 GTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELGK 638
L+ +A M E GS++ +SSI + G + Y SK ++ +T++ A EL
Sbjct: 126 APALMTKAVVPEM-EKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAP 184
Query: 639 FNIRVNAILPGFIDTPIIKTV-PDKVKE 719
NIRVN + PG I T + + DK KE
Sbjct: 185 RNIRVNCLAPGLIKTSFSRMLWMDKEKE 212
>AF044127-1|AAD02292.1| 260|Homo sapiens peroxisomal short-chain
alcohol dehydrogenase protein.
Length = 260
Score = 80.2 bits (189), Expect = 7e-15
Identities = 60/208 (28%), Positives = 103/208 (49%), Gaps = 1/208 (0%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEH 278
+ ++ALVT + GIG A + L+++GA V+ + RK + Q + T G H
Sbjct: 12 LANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCH 71
Query: 279 SAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLK 458
V ++ + LV +K + ++ N+A ++ ++EE +D L++N+K
Sbjct: 72 ------VGKAEDRERLVAMAVKLHGGIDILVSNAAVNPFFGSLMDVTEEVWDKTLDINVK 125
Query: 459 GTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELGK 638
L+ +A M E GS++ +SSI + G + Y SK ++ +T++ A EL
Sbjct: 126 APALMTKAVVPEM-EKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAP 184
Query: 639 FNIRVNAILPGFIDTPIIKTV-PDKVKE 719
NIRVN + PG I T + + DK KE
Sbjct: 185 RNIRVNCLAPGLIKTSFSRMLWMDKEKE 212
>AK001870-1|BAA91953.1| 278|Homo sapiens protein ( Homo sapiens
cDNA FLJ11008 fis, clone PLACE1003100, moderately
similar to HEP27 PROTEIN. ).
Length = 278
Score = 79.0 bits (186), Expect = 2e-14
Identities = 59/208 (28%), Positives = 102/208 (49%), Gaps = 1/208 (0%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEH 278
+ ++AL T + GIG A + L+++GA V+ + RK + Q + T G H
Sbjct: 30 LANKVALATASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCH 89
Query: 279 SAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLK 458
V ++ + LV +K + ++ N+A ++ ++EE +D L++N+K
Sbjct: 90 ------VGKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVK 143
Query: 459 GTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELGK 638
L+ +A M E GS++ +SSI + G + Y SK ++ +T++ A EL
Sbjct: 144 APALMTKAVVPEM-EKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAP 202
Query: 639 FNIRVNAILPGFIDTPIIKTV-PDKVKE 719
NIRVN + PG I T + + DK KE
Sbjct: 203 RNIRVNCLAPGLIKTSFSRMLWMDKEKE 230
>AF064256-1|AAQ13444.1| 278|Homo sapiens Hep27-like protein
protein.
Length = 278
Score = 78.2 bits (184), Expect = 3e-14
Identities = 59/208 (28%), Positives = 102/208 (49%), Gaps = 1/208 (0%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEH 278
+ ++ALVT + GIG A + L+++GA V+ + RK + Q + T G
Sbjct: 30 LANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTG---- 85
Query: 279 SAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLK 458
V ++ + LV +K + ++ N+A ++ ++EE +D L++N+K
Sbjct: 86 --TVCMVGKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVK 143
Query: 459 GTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELGK 638
L+ +A M E GS++ +SSI + G + Y SK ++ +T++ A EL
Sbjct: 144 APALMTKAVVPEM-EKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAP 202
Query: 639 FNIRVNAILPGFIDTPIIKTV-PDKVKE 719
NIRVN + PG I T + + DK KE
Sbjct: 203 RNIRVNCLAPGLIKTSFSRMLWMDKEKE 230
>BC010740-1|AAH10740.1| 292|Homo sapiens 2,4-dienoyl CoA reductase
2, peroxisomal protein.
Length = 292
Score = 76.2 bits (179), Expect = 1e-13
Identities = 58/195 (29%), Positives = 94/195 (48%), Gaps = 3/195 (1%)
Frame = +3
Query: 96 LVVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEE 275
L+ ++A +TG GSGIG ++ + G + A R + + LA T G
Sbjct: 25 LLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARK---LAGAT--GRR 79
Query: 276 HSAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLK---LSEEDYDSVLN 446
+ +DV AV V LK++ + +I +AG N++ LS + +V++
Sbjct: 80 CLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAG----NFLCPAGALSFNAFKTVMD 135
Query: 447 VNLKGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAK 626
++ GTF V + + G I+NI++ +G G Q + S+KA V AMT+ A
Sbjct: 136 IDTSGTFNVSRVLYEKFFRDH-GGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAV 194
Query: 627 ELGKFNIRVNAILPG 671
E G NIRVN++ PG
Sbjct: 195 EWGPQNIRVNSLAPG 209
>BC002786-1|AAH02786.1| 300|Homo sapiens dehydrogenase/reductase
(SDR family) member 2 protein.
Length = 300
Score = 76.2 bits (179), Expect = 1e-13
Identities = 60/204 (29%), Positives = 100/204 (49%), Gaps = 1/204 (0%)
Frame = +3
Query: 93 GLVVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGE 272
G++ R+A+VTG+ SGIG A + L+++GA V+ + RK + A+A G
Sbjct: 32 GVLANRVAVVTGSTSGIGFAIARRLARDGAHVVISSRKQQ------NVDRAMAKLQGEGL 85
Query: 273 EHSAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITR-DNWMLKLSEEDYDSVLNV 449
+ + V ++ + LV L+ +V SAG+ L SE+ +D +L+V
Sbjct: 86 SVAGIVCHVGKAEDREQLVAKALEHCGGVD-FLVCSAGVNPLVGSTLGTSEQIWDKILSV 144
Query: 450 NLKGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKE 629
N+K L++ M G++I +SSI + Y SK ++ +T++ A E
Sbjct: 145 NVKSPALLLSQLLPYMENRR--GAVILVSSIAAYNPVVALGVYNVSKTALLGLTRTLALE 202
Query: 630 LGKFNIRVNAILPGFIDTPIIKTV 701
L +IRVN ++PG I T K V
Sbjct: 203 LAPKDIRVNCVVPGIIKTDFSKVV 226
>AL023881-5|CAB92744.1| 292|Homo sapiens 2,4-dienoyl CoA reductase
2, peroxisomal protein.
Length = 292
Score = 76.2 bits (179), Expect = 1e-13
Identities = 58/195 (29%), Positives = 94/195 (48%), Gaps = 3/195 (1%)
Frame = +3
Query: 96 LVVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEE 275
L+ ++A +TG GSGIG ++ + G + A R + + LA T G
Sbjct: 25 LLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARK---LAGAT--GRR 79
Query: 276 HSAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLK---LSEEDYDSVLN 446
+ +DV AV V LK++ + +I +AG N++ LS + +V++
Sbjct: 80 CLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAG----NFLCPAGALSFNAFKTVMD 135
Query: 447 VNLKGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAK 626
++ GTF V + + G I+NI++ +G G Q + S+KA V AMT+ A
Sbjct: 136 IDTSGTFNVSRVLYEKFFRDH-GGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAV 194
Query: 627 ELGKFNIRVNAILPG 671
E G NIRVN++ PG
Sbjct: 195 EWGPQNIRVNSLAPG 209
>AJ293009-1|CAC05664.1| 292|Homo sapiens peroxisomal
2,4-dienoyl-CoA reductase protein.
Length = 292
Score = 76.2 bits (179), Expect = 1e-13
Identities = 58/195 (29%), Positives = 94/195 (48%), Gaps = 3/195 (1%)
Frame = +3
Query: 96 LVVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEE 275
L+ ++A +TG GSGIG ++ + G + A R + + LA T G
Sbjct: 25 LLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARK---LAGAT--GRR 79
Query: 276 HSAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLK---LSEEDYDSVLN 446
+ +DV AV V LK++ + +I +AG N++ LS + +V++
Sbjct: 80 CLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAG----NFLCPAGALSFNAFKTVMD 135
Query: 447 VNLKGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAK 626
++ GTF V + + G I+NI++ +G G Q + S+KA V AMT+ A
Sbjct: 136 IDTSGTFNVSRVLYEKFFRDH-GGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAV 194
Query: 627 ELGKFNIRVNAILPG 671
E G NIRVN++ PG
Sbjct: 195 EWGPQNIRVNSLAPG 209
>AE006463-11|AAK61231.1| 292|Homo sapiens 2-4-dienoyl-Coenzyme A
reductase 2 peroxisomal like protein.
Length = 292
Score = 76.2 bits (179), Expect = 1e-13
Identities = 58/195 (29%), Positives = 94/195 (48%), Gaps = 3/195 (1%)
Frame = +3
Query: 96 LVVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEE 275
L+ ++A +TG GSGIG ++ + G + A R + + LA T G
Sbjct: 25 LLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARK---LAGAT--GRR 79
Query: 276 HSAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLK---LSEEDYDSVLN 446
+ +DV AV V LK++ + +I +AG N++ LS + +V++
Sbjct: 80 CLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAG----NFLCPAGALSFNAFKTVMD 135
Query: 447 VNLKGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAK 626
++ GTF V + + G I+NI++ +G G Q + S+KA V AMT+ A
Sbjct: 136 IDTSGTFNVSRVLYEKFFRDH-GGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAV 194
Query: 627 ELGKFNIRVNAILPG 671
E G NIRVN++ PG
Sbjct: 195 EWGPQNIRVNSLAPG 209
>U31875-1|AAA82048.1| 280|Homo sapiens Hep27 protein protein.
Length = 280
Score = 74.5 bits (175), Expect = 4e-13
Identities = 59/202 (29%), Positives = 99/202 (49%), Gaps = 1/202 (0%)
Frame = +3
Query: 93 GLVVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGE 272
G++ R+A+VTG+ SGIG A + L+++GA V+ + RK + A+A G
Sbjct: 32 GVLANRVAVVTGSTSGIGFAIARRLARDGAHVVISSRKQQ------NVDRAMAKLQGEGL 85
Query: 273 EHSAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITR-DNWMLKLSEEDYDSVLNV 449
+ + V ++ + LV L+ +V SAG+ L SE+ +D +L+V
Sbjct: 86 SVAGIVCHVGKAEDREQLVAKALEHCGGVD-FLVCSAGVNPLVGSTLGTSEQIWDKILSV 144
Query: 450 NLKGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKE 629
N+K L++ M G++I +SSI + Y SK ++ +T++ A E
Sbjct: 145 NVKSPALLLSQLLPYMENRR--GAVILVSSIAAYNPVVALGVYNVSKTALLGLTRTLALE 202
Query: 630 LGKFNIRVNAILPGFIDTPIIK 695
L +IRVN ++PG I T K
Sbjct: 203 LAPKDIRVNCVVPGIIKTDFSK 224
>BC009830-1|AAH09830.1| 336|Homo sapiens retinol dehydrogenase 14
(all-trans/9-cis/11-cis) protein.
Length = 336
Score = 74.5 bits (175), Expect = 4e-13
Identities = 64/218 (29%), Positives = 106/218 (48%), Gaps = 21/218 (9%)
Frame = +3
Query: 93 GLVVGRLALVTGAGSGIGRAACQVLSKEGATVIAADR---KYEAAVQTIKTHTALA---- 251
GL+ G+ L+TGA SG+GRA L + GA VI R + E A ++ A
Sbjct: 39 GLMHGKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRRELRQAAECG 98
Query: 252 --PGTNGGEEHSAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEE 425
PG +G E ELD+++ ++V+ Q+ L++ + +++N+AGI + +M +E+
Sbjct: 99 PEPGVSGVGELIVRELDLASLRSVRAFCQEMLQEEPRLD-VLINNAGIFQCPYM--KTED 155
Query: 426 DYDSVLNVNLKGTFLVMQAFAKAMAESSVTGSIINISSIVGKYG--NMGQTN-------- 575
++ VN G FL+ + +SS I+ +SS + KYG N N
Sbjct: 156 GFEMQFGVNHLGHFLLTNLLL-GLLKSSAPSRIVVVSSKLYKYGDINFDDLNSEQSYNKS 214
Query: 576 --YASSKAGVVAMTQSAAKELGKFNIRVNAILPGFIDT 683
Y+ SK + T+ A+ L N+ VN + PG + T
Sbjct: 215 FCYSRSKLANILFTRELARRLEGTNVTVNVLHPGIVRT 252
>BC007339-1|AAH07339.2| 271|Homo sapiens DHRS2 protein protein.
Length = 271
Score = 74.5 bits (175), Expect = 4e-13
Identities = 59/202 (29%), Positives = 99/202 (49%), Gaps = 1/202 (0%)
Frame = +3
Query: 93 GLVVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGE 272
G++ R+A+VTG+ SGIG A + L+++GA V+ + RK + A+A G
Sbjct: 23 GVLANRVAVVTGSTSGIGFAIARRLARDGAHVVISSRKQQ------NVDRAMAKLQGEGL 76
Query: 273 EHSAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITR-DNWMLKLSEEDYDSVLNV 449
+ + V ++ + LV L+ +V SAG+ L SE+ +D +L+V
Sbjct: 77 SVAGIVCHVGKAEDREQLVAKALEHCGGVD-FLVCSAGVNPLVGSTLGTSEQIWDKILSV 135
Query: 450 NLKGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKE 629
N+K L++ M G++I +SSI + Y SK ++ +T++ A E
Sbjct: 136 NVKSPALLLSQLLPYMENRR--GAVILVSSIAAYNPVVALGVYNVSKTALLGLTRTLALE 193
Query: 630 LGKFNIRVNAILPGFIDTPIIK 695
L +IRVN ++PG I T K
Sbjct: 194 LAPKDIRVNCVVPGIIKTDFSK 215
>AY358511-1|AAQ88875.1| 336|Homo sapiens PAN2 protein.
Length = 336
Score = 74.5 bits (175), Expect = 4e-13
Identities = 64/218 (29%), Positives = 106/218 (48%), Gaps = 21/218 (9%)
Frame = +3
Query: 93 GLVVGRLALVTGAGSGIGRAACQVLSKEGATVIAADR---KYEAAVQTIKTHTALA---- 251
GL+ G+ L+TGA SG+GRA L + GA VI R + E A ++ A
Sbjct: 39 GLMHGKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRRELRQAAECG 98
Query: 252 --PGTNGGEEHSAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEE 425
PG +G E ELD+++ ++V+ Q+ L++ + +++N+AGI + +M +E+
Sbjct: 99 PEPGVSGVGELIVRELDLASLRSVRAFCQEMLQEEPRLD-VLINNAGIFQCPYM--KTED 155
Query: 426 DYDSVLNVNLKGTFLVMQAFAKAMAESSVTGSIINISSIVGKYG--NMGQTN-------- 575
++ VN G FL+ + +SS I+ +SS + KYG N N
Sbjct: 156 GFEMQFGVNHLGHFLLTNLLL-GLLKSSAPSRIVVVSSKLYKYGDINFDDLNSEQSYNKS 214
Query: 576 --YASSKAGVVAMTQSAAKELGKFNIRVNAILPGFIDT 683
Y+ SK + T+ A+ L N+ VN + PG + T
Sbjct: 215 FCYSRSKLANILFTRELARRLEGTNVTVNVLHPGIVRT 252
>AF244132-1|AAG33703.1| 280|Homo sapiens short-chain alcohol
dehydrogenase protein.
Length = 280
Score = 74.5 bits (175), Expect = 4e-13
Identities = 59/202 (29%), Positives = 99/202 (49%), Gaps = 1/202 (0%)
Frame = +3
Query: 93 GLVVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGE 272
G++ R+A+VTG+ SGIG A + L+++GA V+ + RK + A+A G
Sbjct: 32 GVLANRVAVVTGSTSGIGFAIARRLARDGAHVVISSRKQQ------NVDRAMAKLQGEGL 85
Query: 273 EHSAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITR-DNWMLKLSEEDYDSVLNV 449
+ + V ++ + LV L+ +V SAG+ L SE+ +D +L+V
Sbjct: 86 SVAGIVCHVGKAEDREQLVAKALEHCGGVD-FLVCSAGVNPLVGSTLGTSEQIWDKILSV 144
Query: 450 NLKGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKE 629
N+K L++ M G++I +SSI + Y SK ++ +T++ A E
Sbjct: 145 NVKSPALLLSQLLPYMENRR--GAVILVSSIAAYNPVVALGVYNVSKTALLGLTRTLALE 202
Query: 630 LGKFNIRVNAILPGFIDTPIIK 695
L +IRVN ++PG I T K
Sbjct: 203 LAPKDIRVNCVVPGIIKTDFSK 224
>AF237952-1|AAG12190.1| 336|Homo sapiens PAN2 protein.
Length = 336
Score = 74.5 bits (175), Expect = 4e-13
Identities = 64/218 (29%), Positives = 106/218 (48%), Gaps = 21/218 (9%)
Frame = +3
Query: 93 GLVVGRLALVTGAGSGIGRAACQVLSKEGATVIAADR---KYEAAVQTIKTHTALA---- 251
GL+ G+ L+TGA SG+GRA L + GA VI R + E A ++ A
Sbjct: 39 GLMHGKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRRELRQAAECG 98
Query: 252 --PGTNGGEEHSAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEE 425
PG +G E ELD+++ ++V+ Q+ L++ + +++N+AGI + +M +E+
Sbjct: 99 PEPGVSGVGELIVRELDLASLRSVRAFCQEMLQEEPRLD-VLINNAGIFQCPYM--KTED 155
Query: 426 DYDSVLNVNLKGTFLVMQAFAKAMAESSVTGSIINISSIVGKYG--NMGQTN-------- 575
++ VN G FL+ + +SS I+ +SS + KYG N N
Sbjct: 156 GFEMQFGVNHLGHFLLTNLLL-GLLKSSAPSRIVVVSSKLYKYGDINFDDLNSEQSYNKS 214
Query: 576 --YASSKAGVVAMTQSAAKELGKFNIRVNAILPGFIDT 683
Y+ SK + T+ A+ L N+ VN + PG + T
Sbjct: 215 FCYSRSKLANILFTRELARRLEGTNVTVNVLHPGIVRT 252
>AC079148-1|AAX93259.1| 336|Homo sapiens unknown protein.
Length = 336
Score = 74.5 bits (175), Expect = 4e-13
Identities = 64/218 (29%), Positives = 106/218 (48%), Gaps = 21/218 (9%)
Frame = +3
Query: 93 GLVVGRLALVTGAGSGIGRAACQVLSKEGATVIAADR---KYEAAVQTIKTHTALA---- 251
GL+ G+ L+TGA SG+GRA L + GA VI R + E A ++ A
Sbjct: 39 GLMHGKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRRELRQAAECG 98
Query: 252 --PGTNGGEEHSAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEE 425
PG +G E ELD+++ ++V+ Q+ L++ + +++N+AGI + +M +E+
Sbjct: 99 PEPGVSGVGELIVRELDLASLRSVRAFCQEMLQEEPRLD-VLINNAGIFQCPYM--KTED 155
Query: 426 DYDSVLNVNLKGTFLVMQAFAKAMAESSVTGSIINISSIVGKYG--NMGQTN-------- 575
++ VN G FL+ + +SS I+ +SS + KYG N N
Sbjct: 156 GFEMQFGVNHLGHFLLTNLLL-GLLKSSAPSRIVVVSSKLYKYGDINFDDLNSEQSYNKS 214
Query: 576 --YASSKAGVVAMTQSAAKELGKFNIRVNAILPGFIDT 683
Y+ SK + T+ A+ L N+ VN + PG + T
Sbjct: 215 FCYSRSKLANILFTRELARRLEGTNVTVNVLHPGIVRT 252
>Z97054-7|CAI42652.1| 252|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 10 protein.
Length = 252
Score = 74.1 bits (174), Expect = 5e-13
Identities = 65/219 (29%), Positives = 104/219 (47%), Gaps = 14/219 (6%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKY---EAAVQTIKTHTALAPGTNGG 269
V G +A++TG SG+G A + L +GA+ + D EA + + + AP
Sbjct: 8 VKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPA---- 63
Query: 270 EEHSAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGIT--RDNWMLKLSE----EDY 431
DV++ K VQ + ++ + + VN AGI + LK + ED+
Sbjct: 64 --------DVTSEKDVQTALALAKGKFGRVD-VAVNCAGIAVASKTYNLKKGQTHTLEDF 114
Query: 432 DSVLNVNLKGTFLVMQAFAKAMAESSVT-----GSIINISSIVGKYGNMGQTNYASSKAG 596
VL+VNL GTF V++ A M ++ G IIN +S+ G +GQ Y++SK G
Sbjct: 115 QRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGG 174
Query: 597 VVAMTQSAAKELGKFNIRVNAILPGFIDTPIIKTVPDKV 713
+V MT A++L G TP++ ++P+KV
Sbjct: 175 IVGMTLPIARDLAPI---------GLFGTPLLTSLPEKV 204
>BC008708-1|AAH08708.1| 252|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 10 protein.
Length = 252
Score = 74.1 bits (174), Expect = 5e-13
Identities = 65/219 (29%), Positives = 104/219 (47%), Gaps = 14/219 (6%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKY---EAAVQTIKTHTALAPGTNGG 269
V G +A++TG SG+G A + L +GA+ + D EA + + + AP
Sbjct: 8 VKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPA---- 63
Query: 270 EEHSAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGIT--RDNWMLKLSE----EDY 431
DV++ K VQ + ++ + + VN AGI + LK + ED+
Sbjct: 64 --------DVTSEKDVQTALALAKGKFGRVD-VAVNCAGIAVASKTYNLKKGQTHTLEDF 114
Query: 432 DSVLNVNLKGTFLVMQAFAKAMAESSVT-----GSIINISSIVGKYGNMGQTNYASSKAG 596
VL+VNL GTF V++ A M ++ G IIN +S+ G +GQ Y++SK G
Sbjct: 115 QRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGG 174
Query: 597 VVAMTQSAAKELGKFNIRVNAILPGFIDTPIIKTVPDKV 713
+V MT A++L G TP++ ++P+KV
Sbjct: 175 IVGMTLPIARDLAPI---------GLFGTPLLTSLPEKV 204
>BC011964-1|AAH11964.1| 343|Homo sapiens 3-hydroxybutyrate
dehydrogenase, type 1 protein.
Length = 343
Score = 73.3 bits (172), Expect = 8e-13
Identities = 55/194 (28%), Positives = 95/194 (48%), Gaps = 3/194 (1%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEH 278
V + LVTG SG G A + L +G V A + +K +L +
Sbjct: 53 VGSKAVLVTGCDSGFGFALAKHLHSKGFLVFAGCLMKDKGHDGVKELDSL-----NSDRL 107
Query: 279 SAVELDVSNSKAVQ---DLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNV 449
V+L+V +S+ V+ ++V+ +LK +K +VN+AGI+ + S E Y V V
Sbjct: 108 RTVQLNVCSSEEVEKVVEIVRSSLKDPEKGMWGLVNNAGISTFGEVEFTSLETYKQVAEV 167
Query: 450 NLKGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKE 629
NL GT + ++F + + G ++NISS++G+ N ++ Y +K GV A + E
Sbjct: 168 NLWGTVRMTKSFLPLIRRAK--GRVVNISSMLGRMANPARSPYCITKFGVEAFSDCLRYE 225
Query: 630 LGKFNIRVNAILPG 671
+ ++V+ + PG
Sbjct: 226 MYPLGVKVSVVEPG 239
>AK222857-1|BAD96577.1| 280|Homo sapiens dehydrogenase/reductase
(SDR family) member 2 isoform 2 variant protein.
Length = 280
Score = 72.5 bits (170), Expect = 1e-12
Identities = 57/202 (28%), Positives = 99/202 (49%), Gaps = 1/202 (0%)
Frame = +3
Query: 93 GLVVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGE 272
G++ R+A+VTG+ SGIG A + L+++GA V+ + RK + A+A G
Sbjct: 32 GVLANRVAVVTGSTSGIGFAIARRLARDGAHVVISSRKQQ------NVDRAMAKLQGEGL 85
Query: 273 EHSAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITR-DNWMLKLSEEDYDSVLNV 449
+ + V ++ + LV L+ +V SAG+ L SE+ +D +L+V
Sbjct: 86 SVAGIVCHVGKAEDREQLVAKALEHCGGVD-FLVCSAGVNPLVGSTLGTSEQIWDKILSV 144
Query: 450 NLKGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKE 629
N+K ++ M G++I +SS+ + Y+ SK ++ +T++ A E
Sbjct: 145 NVKSPAPLLSQLLPYMENRR--GAVILVSSVAAYNPVVALGVYSVSKTALLGLTRTLALE 202
Query: 630 LGKFNIRVNAILPGFIDTPIIK 695
L +IRVN ++PG I T K
Sbjct: 203 LAPKDIRVNCVVPGIIKTDFSK 224
>BC019317-1|AAH19317.1| 343|Homo sapiens 3-hydroxybutyrate
dehydrogenase, type 1 protein.
Length = 343
Score = 72.1 bits (169), Expect = 2e-12
Identities = 54/194 (27%), Positives = 95/194 (48%), Gaps = 3/194 (1%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEH 278
V + LVTG SG G + + L +G V A + +K +L +
Sbjct: 53 VGSKAVLVTGCDSGFGFSLAKHLHSKGFLVFAGCLMKDKGHDGVKELDSL-----NSDRL 107
Query: 279 SAVELDVSNSKAVQ---DLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNV 449
V+L+V +S+ V+ ++V+ +LK +K +VN+AGI+ + S E Y V V
Sbjct: 108 RTVQLNVCSSEEVEKVVEIVRSSLKDPEKGMWGLVNNAGISTFGEVEFTSLETYKQVAEV 167
Query: 450 NLKGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKE 629
NL GT + ++F + + G ++NISS++G+ N ++ Y +K GV A + E
Sbjct: 168 NLWGTVRMTKSFLPLIRRAK--GRVVNISSMLGRMANPARSPYCITKFGVEAFSDCLRYE 225
Query: 630 LGKFNIRVNAILPG 671
+ ++V+ + PG
Sbjct: 226 MYPLGVKVSVVEPG 239
>BC005844-1|AAH05844.1| 343|Homo sapiens 3-hydroxybutyrate
dehydrogenase, type 1 protein.
Length = 343
Score = 72.1 bits (169), Expect = 2e-12
Identities = 54/194 (27%), Positives = 95/194 (48%), Gaps = 3/194 (1%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEH 278
V + LVTG SG G + + L +G V A + +K +L +
Sbjct: 53 VGSKAVLVTGCDSGFGFSLAKHLHSKGFLVFAGCLMKDKGHDGVKELDSL-----NSDRL 107
Query: 279 SAVELDVSNSKAVQ---DLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNV 449
V+L+V +S+ V+ ++V+ +LK +K +VN+AGI+ + S E Y V V
Sbjct: 108 RTVQLNVCSSEEVEKVVEIVRSSLKDPEKGMWGLVNNAGISTFGEVEFTSLETYKQVAEV 167
Query: 450 NLKGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKE 629
NL GT + ++F + + G ++NISS++G+ N ++ Y +K GV A + E
Sbjct: 168 NLWGTVRMTKSFLPLIRRAK--GRVVNISSMLGRMANPARSPYCITKFGVEAFSDCLRYE 225
Query: 630 LGKFNIRVNAILPG 671
+ ++V+ + PG
Sbjct: 226 MYPLGVKVSVVEPG 239
>BC002731-1|AAH02731.2| 260|Homo sapiens short-chain
dehydrogenase/reductase protein.
Length = 260
Score = 72.1 bits (169), Expect = 2e-12
Identities = 60/209 (28%), Positives = 99/209 (47%), Gaps = 5/209 (2%)
Frame = +3
Query: 108 RLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHSAV 287
RLALVTGA GIG A + L ++G V+ R V I+ A
Sbjct: 12 RLALVTGASGGIGAAVARALVQQGLKVVGCAR----TVGNIEELAAECKSAGYPGTLIPY 67
Query: 288 ELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLKGTF 467
D+SN + + + Q+ I +N+AG+ R + +L S + + NVN+
Sbjct: 68 RCDLSNEEDILSMFSAIRSQHSGVD-ICINNAGLARPDTLLSGSTSGWKDMFNVNVLALS 126
Query: 468 LVMQAFAKAMAESSV-TGSIINISSIVG-KYGNMGQTN-YASSKAGVVAMTQSAAKEL-- 632
+ + ++M E +V G IINI+S+ G + + T+ Y+++K V A+T+ +EL
Sbjct: 127 ICTREAYQSMKERNVDDGHIININSMSGHRVLPLSVTHFYSATKYAVTALTEGLRQELRE 186
Query: 633 GKFNIRVNAILPGFIDTPIIKTVPDKVKE 719
+ +IR I PG ++T + DK E
Sbjct: 187 AQTHIRATCISPGVVETQFAFKLHDKDPE 215
>AY358712-1|AAQ89074.1| 260|Homo sapiens ARPG836 protein.
Length = 260
Score = 72.1 bits (169), Expect = 2e-12
Identities = 60/209 (28%), Positives = 99/209 (47%), Gaps = 5/209 (2%)
Frame = +3
Query: 108 RLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHSAV 287
RLALVTGA GIG A + L ++G V+ R V I+ A
Sbjct: 12 RLALVTGASGGIGAAVARALVQQGLKVVGCAR----TVGNIEELAAECKSAGYPGTLIPY 67
Query: 288 ELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLKGTF 467
D+SN + + + Q+ I +N+AG+ R + +L S + + NVN+
Sbjct: 68 RCDLSNEEDILSMFSAIRSQHSGVD-ICINNAGLARPDTLLSGSTSGWKDMFNVNVLALS 126
Query: 468 LVMQAFAKAMAESSV-TGSIINISSIVG-KYGNMGQTN-YASSKAGVVAMTQSAAKEL-- 632
+ + ++M E +V G IINI+S+ G + + T+ Y+++K V A+T+ +EL
Sbjct: 127 ICTREAYQSMKERNVDDGHIININSMSGHRVLPLSVTHFYSATKYAVTALTEGLRQELRE 186
Query: 633 GKFNIRVNAILPGFIDTPIIKTVPDKVKE 719
+ +IR I PG ++T + DK E
Sbjct: 187 AQTHIRATCISPGVVETQFAFKLHDKDPE 215
>BC112305-1|AAI12306.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 13 protein.
Length = 300
Score = 70.5 bits (165), Expect = 6e-12
Identities = 59/215 (27%), Positives = 93/215 (43%), Gaps = 6/215 (2%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEH 278
V G + L+TGAG GIGR +K + ++ D +T L G H
Sbjct: 34 VAGEIVLITGAGHGIGRQTTYEFAKRQSILVLWDINKRGVEETAAECRKL-----GVTAH 88
Query: 279 SAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLK 458
+ V +D SN + + + K+ I+VN+AG +L +E+ VN+
Sbjct: 89 AYV-VDCSNREEIYRSLNQVKKEV-GDVTIVVNNAGTVYPADLLSTKDEEITKTFEVNIL 146
Query: 459 GTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKE--- 629
G F + +A +M E + G I+ ++S+ G G Y SSK V + E
Sbjct: 147 GHFWITKALLPSMMERN-HGHIVTVASVCGHEGIPYLIPYCSSKFAAVGFHRGLTSELQA 205
Query: 630 LGKFNIRVNAILPGFIDTPIIKTVPDK---VKETD 725
LGK I+ + + P F++T K + V ETD
Sbjct: 206 LGKTGIKTSCLCPVFVNTGFTKNPSTRLWPVLETD 240
>BC112303-1|AAI12304.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 13 protein.
Length = 300
Score = 70.5 bits (165), Expect = 6e-12
Identities = 59/215 (27%), Positives = 93/215 (43%), Gaps = 6/215 (2%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEH 278
V G + L+TGAG GIGR +K + ++ D +T L G H
Sbjct: 34 VAGEIVLITGAGHGIGRQTTYEFAKRQSILVLWDINKRGVEETAAECRKL-----GVTAH 88
Query: 279 SAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLK 458
+ V +D SN + + + K+ I+VN+AG +L +E+ VN+
Sbjct: 89 AYV-VDCSNREEIYRSLNQVKKEV-GDVTIVVNNAGTVYPADLLSTKDEEITKTFEVNIL 146
Query: 459 GTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKE--- 629
G F + +A +M E + G I+ ++S+ G G Y SSK V + E
Sbjct: 147 GHFWITKALLPSMMERN-HGHIVTVASVCGHEGIPYLIPYCSSKFAAVGFHRGLTSELQA 205
Query: 630 LGKFNIRVNAILPGFIDTPIIKTVPDK---VKETD 725
LGK I+ + + P F++T K + V ETD
Sbjct: 206 LGKTGIKTSCLCPVFVNTGFTKNPSTRLWPVLETD 240
>AY358575-1|AAQ88938.1| 300|Homo sapiens NIIL497 protein.
Length = 300
Score = 70.5 bits (165), Expect = 6e-12
Identities = 59/215 (27%), Positives = 93/215 (43%), Gaps = 6/215 (2%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEH 278
V G + L+TGAG GIGR +K + ++ D +T L G H
Sbjct: 34 VAGEIVLITGAGHGIGRQTTYEFAKRQSILVLWDINKRGVEETAAECRKL-----GVTAH 88
Query: 279 SAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLK 458
+ V +D SN + + + K+ I+VN+AG +L +E+ VN+
Sbjct: 89 AYV-VDCSNREEIYRSLNQVKKEV-GDVTIVVNNAGTVYPADLLSTKDEEITKTFEVNIL 146
Query: 459 GTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKE--- 629
G F + +A +M E + G I+ ++S+ G G Y SSK V + E
Sbjct: 147 GHFWITKALLPSMMERN-HGHIVTVASVCGHEGIPYLIPYCSSKFAAVGFHRGLTSELQA 205
Query: 630 LGKFNIRVNAILPGFIDTPIIKTVPDK---VKETD 725
LGK I+ + + P F++T K + V ETD
Sbjct: 206 LGKTGIKTSCLCPVFVNTGFTKNPSTRLWPVLETD 240
>AY268355-1|AAP42289.1| 300|Homo sapiens short-chain
dehydrogenase/reductase 9 protein.
Length = 300
Score = 70.5 bits (165), Expect = 6e-12
Identities = 59/215 (27%), Positives = 93/215 (43%), Gaps = 6/215 (2%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEH 278
V G + L+TGAG GIGR +K + ++ D +T L G H
Sbjct: 34 VAGEIVLITGAGHGIGRQTTYEFAKRQSILVLWDINKRGVEETAAECRKL-----GVTAH 88
Query: 279 SAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLK 458
+ V +D SN + + + K+ I+VN+AG +L +E+ VN+
Sbjct: 89 AYV-VDCSNREEIYRSLNQVKKEV-GDVTIVVNNAGTVYPADLLSTKDEEITKTFEVNIL 146
Query: 459 GTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKE--- 629
G F + +A +M E + G I+ ++S+ G G Y SSK V + E
Sbjct: 147 GHFWITKALLPSMMERN-HGHIVTVASVCGHEGIPYLIPYCSSKFAAVGFHRGLTSELQA 205
Query: 630 LGKFNIRVNAILPGFIDTPIIKTVPDK---VKETD 725
LGK I+ + + P F++T K + V ETD
Sbjct: 206 LGKTGIKTSCLCPVFVNTGFTKNPSTRLWPVLETD 240
>AY186249-1|AAO72313.1| 300|Homo sapiens 17-beta hydroxysteroid
dehydrogenase protein.
Length = 300
Score = 70.5 bits (165), Expect = 6e-12
Identities = 59/215 (27%), Positives = 93/215 (43%), Gaps = 6/215 (2%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEH 278
V G + L+TGAG GIGR +K + ++ D +T L G H
Sbjct: 34 VAGEIVLITGAGHGIGRQTTYEFAKRQSILVLWDINKRGVEETAAECRKL-----GVTAH 88
Query: 279 SAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLK 458
+ V +D SN + + + K+ I+VN+AG +L +E+ VN+
Sbjct: 89 AYV-VDCSNREEIYRSLNQVKKEV-GDVTIVVNNAGTVYPADLLSTKDEEITKTFEVNIL 146
Query: 459 GTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKE--- 629
G F + +A +M E + G I+ ++S+ G G Y SSK V + E
Sbjct: 147 GHFWITKALLPSMMERN-HGHIVTVASVCGHEGIPYLIPYCSSKFAAVGFHRGLTSELQA 205
Query: 630 LGKFNIRVNAILPGFIDTPIIKTVPDK---VKETD 725
LGK I+ + + P F++T K + V ETD
Sbjct: 206 LGKTGIKTSCLCPVFVNTGFTKNPSTRLWPVLETD 240
>AB073347-1|BAD38632.1| 300|Homo sapiens putative protein product
of HMFN0376 protein.
Length = 300
Score = 70.5 bits (165), Expect = 6e-12
Identities = 59/215 (27%), Positives = 93/215 (43%), Gaps = 6/215 (2%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEH 278
V G + L+TGAG GIGR +K + ++ D +T L G H
Sbjct: 34 VAGEIVLITGAGHGIGRQTTYEFAKRQSILVLWDINKRGVEETAAECRKL-----GVTAH 88
Query: 279 SAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLK 458
+ V +D SN + + + K+ I+VN+AG +L +E+ VN+
Sbjct: 89 AYV-VDCSNREEIYRSLNQVKKEV-GDVTIVVNNAGTVYPADLLSTKDEEITKTFEVNIL 146
Query: 459 GTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKE--- 629
G F + +A +M E + G I+ ++S+ G G Y SSK V + E
Sbjct: 147 GHFWITKALLPSMMERN-HGHIVTVASVCGHEGIPYLIPYCSSKFAAVGFHRGLTSELQA 205
Query: 630 LGKFNIRVNAILPGFIDTPIIKTVPDK---VKETD 725
LGK I+ + + P F++T K + V ETD
Sbjct: 206 LGKTGIKTSCLCPVFVNTGFTKNPSTRLWPVLETD 240
>X82460-1|CAA57843.1| 178|Homo sapiens 15-hydroxy prostaglandin
dehydrogenase protein.
Length = 178
Score = 69.7 bits (163), Expect = 1e-11
Identities = 57/176 (32%), Positives = 90/176 (51%), Gaps = 1/176 (0%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEH 278
V G++ALVTGA GIGRA + L +GA V D EA VQ A ++
Sbjct: 3 VNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQC----KAALDEQFEPQKT 58
Query: 279 SAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGI-TRDNWMLKLSEEDYDSVLNVNL 455
++ DV++ + ++D + + + + I+VN+AG+ + NW K + + SV++
Sbjct: 59 LFIQCDVADQQQLRDTFRKVVDHFGRLD-ILVNNAGVNNKKNWE-KTLQINLVSVIS--- 113
Query: 456 KGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAA 623
GT+L + +K G IIN+SS+ G Q Y +SK G+V T+SAA
Sbjct: 114 -GTYLGLDYMSK--QNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAA 166
>BC028298-1|AAH28298.1| 318|Homo sapiens retinol dehydrogenase 5
(11-cis/9-cis) protein.
Length = 318
Score = 67.3 bits (157), Expect = 5e-11
Identities = 54/195 (27%), Positives = 92/195 (47%), Gaps = 2/195 (1%)
Frame = +3
Query: 111 LALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHSAVE 290
L +TG SG GR L + G V+A+ A + ++ H+ +
Sbjct: 30 LVFITGCDSGFGRLLALQLDQRGFRVLASCLTPSGAEDLQRVASSRL--------HTTL- 80
Query: 291 LDVSNSKAVQDLVQDTLKQYKKPPCI-IVNSAGITRDNWMLK-LSEEDYDSVLNVNLKGT 464
LD+++ ++VQ + K+ +VN+AG+ L+ +D+ VLNVN G
Sbjct: 81 LDITDPQSVQQAAKWVEMHVKEAGLFGLVNNAGVAGIIGPTPWLTRDDFQRVLNVNTMGP 140
Query: 465 FLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELGKFN 644
V A + ++ G +INI+S++G+ G Y SK G+ A + S +++ F
Sbjct: 141 IGVTLALLPLLQQAR--GRVINITSVLGRLAANGG-GYCVSKFGLEAFSDSLRRDVAHFG 197
Query: 645 IRVNAILPGFIDTPI 689
IRV+ + PGF TP+
Sbjct: 198 IRVSIVEPGFFRTPV 212
>AF057034-1|AAC39922.1| 317|Homo sapiens sterol/retinol
dehydrogenase protein.
Length = 317
Score = 67.3 bits (157), Expect = 5e-11
Identities = 60/226 (26%), Positives = 109/226 (48%), Gaps = 5/226 (2%)
Frame = +3
Query: 27 ILLLRFCEFYTIF*IIQDNMVSGLVVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRK 206
+ L F Y + ++ V + + +TG SG G+ + L G V+AA
Sbjct: 3 LYLAVFVGLYYLLHWYRERQVLSHLRDKYVFITGCDSGFGKLLARQLDARGLRVLAACLT 62
Query: 207 YEAAVQTIKTHTALAPGTNGGEEHSAVELDVSNSKAVQDLVQDTLKQYKKPPCI--IVNS 380
+ A Q ++ T+ + V LDV+ +++V Q +K+ + + +VN+
Sbjct: 63 EKGAEQ-LRGQTS--------DRLETVTLDVTKTESVAAAAQ-WVKECVRDKGLWGLVNN 112
Query: 381 AGI---TRDNWMLKLSEEDYDSVLNVNLKGTFLVMQAFAKAMAESSVTGSIINISSIVGK 551
AGI T N + L+++D+ ++L+VNL G V + + ++ G ++N+SS++G+
Sbjct: 113 AGISLPTAPNEL--LTKQDFVTILDVNLLGVIDVTLSLLPLVRKA--RGRVVNVSSVMGR 168
Query: 552 YGNMGQTNYASSKAGVVAMTQSAAKELGKFNIRVNAILPGFIDTPI 689
G Y SK GV A + S +EL F ++V I PG+ T +
Sbjct: 169 VSLFG-GGYCISKYGVEAFSDSLRRELSYFGVKVAMIEPGYFKTAV 213
>CR457124-1|CAG33405.1| 325|Homo sapiens DKFZp566O084 protein.
Length = 325
Score = 66.9 bits (156), Expect = 7e-11
Identities = 51/191 (26%), Positives = 89/191 (46%)
Frame = +3
Query: 111 LALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHSAVE 290
+ ++TGA SG+G+ +V GA ++ R A + I+ TA + V
Sbjct: 54 VVVITGATSGLGKECAKVFYAAGAKLVLCGRNGGALEELIRELTASHATKVQTHKPYLVT 113
Query: 291 LDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLKGTFL 470
D+++S A+ + L+ + I+VN+AGI+ ++ + + V+ N G
Sbjct: 114 FDLTDSGAIVAAAAEILQCFGYVD-ILVNNAGISYRGTIMDTTVDVDKRVMETNYFGPVA 172
Query: 471 VMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELGKFNIR 650
+ +A +M + G I+ ISSI GK ++ YA+SK A E+ ++ I
Sbjct: 173 LTKALLPSMIKRR-QGHIVAISSIQGKMSIPFRSAYAASKHATQAFFDCLRAEMEQYEIE 231
Query: 651 VNAILPGFIDT 683
V I PG+I T
Sbjct: 232 VTVISPGYIHT 242
>BC009679-1|AAH09679.1| 325|Homo sapiens dehydrogenase/reductase
(SDR family) member 7B protein.
Length = 325
Score = 66.9 bits (156), Expect = 7e-11
Identities = 51/191 (26%), Positives = 89/191 (46%)
Frame = +3
Query: 111 LALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHSAVE 290
+ ++TGA SG+G+ +V GA ++ R A + I+ TA + V
Sbjct: 54 VVVITGATSGLGKECAKVFYAAGAKLVLCGRNGGALEELIRELTASHATKVQTHKPYLVT 113
Query: 291 LDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLKGTFL 470
D+++S A+ + L+ + I+VN+AGI+ ++ + + V+ N G
Sbjct: 114 FDLTDSGAIVAAAAEILQCFGYVD-ILVNNAGISYRGTIMDTTVDVDKRVMETNYFGPVA 172
Query: 471 VMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELGKFNIR 650
+ +A +M + G I+ ISSI GK ++ YA+SK A E+ ++ I
Sbjct: 173 LTKALLPSMIKRR-QGHIVAISSIQGKMSIPFRSAYAASKHATQAFFDCLRAEMEQYEIE 231
Query: 651 VNAILPGFIDT 683
V I PG+I T
Sbjct: 232 VTVISPGYIHT 242
>BC004126-1|AAH04126.1| 325|Homo sapiens dehydrogenase/reductase
(SDR family) member 7B protein.
Length = 325
Score = 66.9 bits (156), Expect = 7e-11
Identities = 51/191 (26%), Positives = 89/191 (46%)
Frame = +3
Query: 111 LALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHSAVE 290
+ ++TGA SG+G+ +V GA ++ R A + I+ TA + V
Sbjct: 54 VVVITGATSGLGKECAKVFYAAGAKLVLCGRNGGALEELIRELTASHATKVQTHKPYLVT 113
Query: 291 LDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLKGTFL 470
D+++S A+ + L+ + I+VN+AGI+ ++ + + V+ N G
Sbjct: 114 FDLTDSGAIVAAAAEILQCFGYVD-ILVNNAGISYRGTIMDTTVDVDKRVMETNYFGPVA 172
Query: 471 VMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELGKFNIR 650
+ +A +M + G I+ ISSI GK ++ YA+SK A E+ ++ I
Sbjct: 173 LTKALLPSMIKRR-QGHIVAISSIQGKMSIPFRSAYAASKHATQAFFDCLRAEMEQYEIE 231
Query: 651 VNAILPGFIDT 683
V I PG+I T
Sbjct: 232 VTVISPGYIHT 242
>AY358498-1|AAQ88862.1| 310|Homo sapiens DFIT212 protein.
Length = 310
Score = 66.9 bits (156), Expect = 7e-11
Identities = 51/191 (26%), Positives = 89/191 (46%)
Frame = +3
Query: 111 LALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHSAVE 290
+ ++TGA SG+G+ +V GA ++ R A + I+ TA + V
Sbjct: 39 VVVITGATSGLGKECAKVFYAAGAKLVLCGRNGGALEELIRELTASHATKVQTHKPYLVT 98
Query: 291 LDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLKGTFL 470
D+++S A+ + L+ + I+VN+AGI+ ++ + + V+ N G
Sbjct: 99 FDLTDSGAIVAAAAEILQCFGYVD-ILVNNAGISYRGTIMDTTVDVDKRVMETNYFGPVA 157
Query: 471 VMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELGKFNIR 650
+ +A +M + G I+ ISSI GK ++ YA+SK A E+ ++ I
Sbjct: 158 LTKALLPSMIKRR-QGHIVAISSIQGKMSIPFRSAYAASKHATQAFFDCLRAEMEQYEIE 216
Query: 651 VNAILPGFIDT 683
V I PG+I T
Sbjct: 217 VTVISPGYIHT 227
>AF151851-1|AAD34088.1| 291|Homo sapiens CGI-93 protein protein.
Length = 291
Score = 66.9 bits (156), Expect = 7e-11
Identities = 51/191 (26%), Positives = 89/191 (46%)
Frame = +3
Query: 111 LALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHSAVE 290
+ ++TGA SG+G+ +V GA ++ R A + I+ TA + V
Sbjct: 59 VVVITGATSGLGKECAKVFYAAGAKLVLCGRNGGALEELIRELTASHATKVQTHKPYLVT 118
Query: 291 LDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLKGTFL 470
D+++S A+ + L+ + I+VN+AGI+ ++ + + V+ N G
Sbjct: 119 FDLTDSGAIVAAAAEILQCFGYVD-ILVNNAGISYRGTIMDTTVDVDKRVMETNYFGPVA 177
Query: 471 VMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELGKFNIR 650
+ +A +M + G I+ ISSI GK ++ YA+SK A E+ ++ I
Sbjct: 178 LTKALLPSMIKRR-QGHIVAISSIQGKMSIPFRSAYAASKHATQAFFDCLRAEMEQYEIE 236
Query: 651 VNAILPGFIDT 683
V I PG+I T
Sbjct: 237 VTVISPGYIHT 247
>BC067131-1|AAH67131.1| 341|Homo sapiens retinol dehydrogenase 10
(all-trans) protein.
Length = 341
Score = 66.5 bits (155), Expect = 9e-11
Identities = 56/221 (25%), Positives = 103/221 (46%), Gaps = 22/221 (9%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQT----------IKTHTAL 248
V G++ L+TGAGSG+GR ++ A ++ D ++ +T ++ A
Sbjct: 34 VAGQVCLITGAGSGLGRLFALEFARRRALLVLWDINTQSNEETAGMVRHIYRDLEAADAA 93
Query: 249 APGTNGGEE----HSAVEL-----DVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDN 401
A GEE H +++ DV + V L + +++ ++VN+AG+ +
Sbjct: 94 ALQAGNGEEEILPHCNLQVFTYTCDVGKRENVY-LTAERVRKEVGEVSVLVNNAGVVSGH 152
Query: 402 WMLKLSEEDYDSVLNVNLKGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYA 581
+L+ +E + + VN F +AF M E + G I+ ++S +G + G +Y
Sbjct: 153 HLLECPDELIERTMMVNCHAHFWTTKAFLPTMLEIN-HGHIVTVASSLGLFSTAGVEDYC 211
Query: 582 SSKAGVVAMTQSAAKEL---GKFNIRVNAILPGFIDTPIIK 695
+SK GVV +S + EL K I+ + P +DT + +
Sbjct: 212 ASKFGVVGFHESLSHELKAAEKDGIKTTLVCPYLVDTGMFR 252
>BC064525-1|AAH64525.1| 309|Homo sapiens epidermal retinal
dehydrogenase 2 protein.
Length = 309
Score = 66.5 bits (155), Expect = 9e-11
Identities = 56/198 (28%), Positives = 85/198 (42%), Gaps = 3/198 (1%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEH 278
V G + L+TGAGSG+GR ++ G+ ++ D E +T K +A H
Sbjct: 38 VAGEIVLITGAGSGLGRLLALQFARLGSVLVLWDINKEGNEETCK----MAREAGATRVH 93
Query: 279 SAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLK 458
A D S + V V D +K+ I++N+AGI L +E + +VN K
Sbjct: 94 -AYTCDCSQKEGVY-RVADQVKKEVGDVSILINNAGIVTGKKFLDCPDELMEKSFDVNFK 151
Query: 459 GTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKEL-- 632
+AF AM + G ++ ISS G G G +Y +SK +S E
Sbjct: 152 AHLWTYKAFLPAMIAND-HGHLVCISSSAGLSGVNGLADYCASKFAAFGFAESVFVETFV 210
Query: 633 -GKFNIRVNAILPGFIDT 683
+ I+ + P FI T
Sbjct: 211 QKQKGIKTTIVCPFFIKT 228
>BC037219-1|AAH37219.2| 309|Homo sapiens epidermal retinal
dehydrogenase 2 protein.
Length = 309
Score = 66.5 bits (155), Expect = 9e-11
Identities = 56/198 (28%), Positives = 85/198 (42%), Gaps = 3/198 (1%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEH 278
V G + L+TGAGSG+GR ++ G+ ++ D E +T K +A H
Sbjct: 38 VAGEIVLITGAGSGLGRLLALQFARLGSVLVLWDINKEGNEETCK----MAREAGATRVH 93
Query: 279 SAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLK 458
A D S + V V D +K+ I++N+AGI L +E + +VN K
Sbjct: 94 -AYTCDCSQKEGVY-RVADQVKKEVGDVSILINNAGIVTGKKFLDCPDELMEKSFDVNFK 151
Query: 459 GTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKEL-- 632
+AF AM + G ++ ISS G G G +Y +SK +S E
Sbjct: 152 AHLWTYKAFLPAMIAND-HGHLVCISSSAGLSGVNGLADYCASKFAAFGFAESVFVETFV 210
Query: 633 -GKFNIRVNAILPGFIDT 683
+ I+ + P FI T
Sbjct: 211 QKQKGIKTTIVCPFFIKT 228
>AY358270-1|AAQ88637.1| 341|Homo sapiens RDH10 protein.
Length = 341
Score = 66.5 bits (155), Expect = 9e-11
Identities = 56/221 (25%), Positives = 103/221 (46%), Gaps = 22/221 (9%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQT----------IKTHTAL 248
V G++ L+TGAGSG+GR ++ A ++ D ++ +T ++ A
Sbjct: 34 VAGQVCLITGAGSGLGRLFALEFARRRALLVLWDINTQSNEETAGMVRHIYRDLEAADAA 93
Query: 249 APGTNGGEE----HSAVEL-----DVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDN 401
A GEE H +++ DV + V L + +++ ++VN+AG+ +
Sbjct: 94 ALQAGNGEEEILPHCNLQVFTYTCDVGKRENVY-LTAERVRKEVGEVSVLVNNAGVVSGH 152
Query: 402 WMLKLSEEDYDSVLNVNLKGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYA 581
+L+ +E + + VN F +AF M E + G I+ ++S +G + G +Y
Sbjct: 153 HLLECPDELIERTMMVNCHAHFWTTKAFLPTMLEIN-HGHIVTVASSLGLFSTAGVEDYC 211
Query: 582 SSKAGVVAMTQSAAKEL---GKFNIRVNAILPGFIDTPIIK 695
+SK GVV +S + EL K I+ + P +DT + +
Sbjct: 212 ASKFGVVGFHESLSHELKAAEKDGIKTTLVCPYLVDTGMFR 252
>AF456765-1|AAN64747.1| 341|Homo sapiens retinol dehydrogenase 10
protein.
Length = 341
Score = 66.5 bits (155), Expect = 9e-11
Identities = 56/221 (25%), Positives = 103/221 (46%), Gaps = 22/221 (9%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQT----------IKTHTAL 248
V G++ L+TGAGSG+GR ++ A ++ D ++ +T ++ A
Sbjct: 34 VAGQVCLITGAGSGLGRLFALEFARRRALLVLWDINTQSNEETAGMVRHIYRDLEAADAA 93
Query: 249 APGTNGGEE----HSAVEL-----DVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDN 401
A GEE H +++ DV + V L + +++ ++VN+AG+ +
Sbjct: 94 ALQAGNGEEEILPHCNLQVFTYTCDVGKRENVY-LTAERVRKEVGEVSVLVNNAGVVSGH 152
Query: 402 WMLKLSEEDYDSVLNVNLKGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYA 581
+L+ +E + + VN F +AF M E + G I+ ++S +G + G +Y
Sbjct: 153 HLLECPDELIERTMMVNCHAHFWTTKAFLPTMLEIN-HGHIVTVASSLGLFSTAGVEDYC 211
Query: 582 SSKAGVVAMTQSAAKEL---GKFNIRVNAILPGFIDTPIIK 695
+SK GVV +S + EL K I+ + P +DT + +
Sbjct: 212 ASKFGVVGFHESLSHELKAAEKDGIKTTLVCPYLVDTGMFR 252
>X63657-1|CAA45197.1| 332|Homo sapiens FVT1 protein.
Length = 332
Score = 66.1 bits (154), Expect = 1e-10
Identities = 50/197 (25%), Positives = 90/197 (45%), Gaps = 3/197 (1%)
Frame = +3
Query: 105 GRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHSA 284
G +VTG SGIG+ K+GA + R + +Q K + N +
Sbjct: 32 GAHVVVTGGSSGIGKCIAIECYKQGAFITLVARNEDKLLQAKKEIEMHS--INDKQVVLC 89
Query: 285 VELDVSNSKAVQDLVQDTLKQYKK---PPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNL 455
+ +DVS + V++ +KQ ++ P ++VN AG+ L ++ ++++N
Sbjct: 90 ISVDVSQD---YNQVENVIKQAQEKLGPVDMLVNCAGMAVSGKFEDLEVSTFERLMSINY 146
Query: 456 KGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELG 635
G+ +A M E V G I+ +SS G+ G G T Y++SK + + ++ E+
Sbjct: 147 LGSVYPSRAVITTMKERRV-GRIVFVSSQAGQLGLFGFTAYSASKFAIRGLAEALQMEVK 205
Query: 636 KFNIRVNAILPGFIDTP 686
+N+ + P DTP
Sbjct: 206 PYNVYITVAYPPDTDTP 222
>M93107-1|AAA58352.1| 343|Homo sapiens (R)-3-hydroxybutyrate
dehydrogenase protein.
Length = 343
Score = 66.1 bits (154), Expect = 1e-10
Identities = 53/194 (27%), Positives = 91/194 (46%), Gaps = 3/194 (1%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEH 278
V + LVTG SG G + + L +G V A + +K +L +
Sbjct: 53 VGSKAVLVTGCDSGFGFSLAKHLHSKGFLVFAGCLMKDKGHDGVKELDSL-----NSDRL 107
Query: 279 SAVELDVSNSKAVQDLVQDTLKQYKKPP---CIIVNSAGITRDNWMLKLSEEDYDSVLNV 449
V+L+V S+ V+ +V D + + P +VN+AGI+ + S E Y V V
Sbjct: 108 RTVQLNVFRSEEVEKVVGDCPFEPEGPEKGMWGLVNNAGISTFGEVEFTSLETYKQVAEV 167
Query: 450 NLKGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKE 629
NL GT + ++F + + G ++NISS++G+ N ++ Y +K GV A + E
Sbjct: 168 NLWGTVRMTKSFLPLIRRAK--GRVVNISSMLGRMANPARSPYCITKFGVEAFSDCLRYE 225
Query: 630 LGKFNIRVNAILPG 671
+ ++V+ + PG
Sbjct: 226 MYPLGVKVSVVEPG 239
>BT006782-1|AAP35428.1| 332|Homo sapiens follicular lymphoma
variant translocation 1 protein.
Length = 332
Score = 66.1 bits (154), Expect = 1e-10
Identities = 50/197 (25%), Positives = 90/197 (45%), Gaps = 3/197 (1%)
Frame = +3
Query: 105 GRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHSA 284
G +VTG SGIG+ K+GA + R + +Q K + N +
Sbjct: 32 GAHVVVTGGSSGIGKCIAIECYKQGAFITLVARNEDKLLQAKKEIEMHS--INDKQVVLC 89
Query: 285 VELDVSNSKAVQDLVQDTLKQYKK---PPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNL 455
+ +DVS + V++ +KQ ++ P ++VN AG+ L ++ ++++N
Sbjct: 90 ISVDVSQD---YNQVENVIKQAQEKLGPVDMLVNCAGMAVSGKFEDLEVSTFERLMSINY 146
Query: 456 KGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELG 635
G+ +A M E V G I+ +SS G+ G G T Y++SK + + ++ E+
Sbjct: 147 LGSVYPSRAVITTMKERRV-GRIVFVSSQAGQLGLFGFTAYSASKFAIRGLAEALQMEVK 205
Query: 636 KFNIRVNAILPGFIDTP 686
+N+ + P DTP
Sbjct: 206 PYNVYITVAYPPDTDTP 222
>BC008797-1|AAH08797.1| 332|Homo sapiens follicular lymphoma
variant translocation 1 protein.
Length = 332
Score = 66.1 bits (154), Expect = 1e-10
Identities = 50/197 (25%), Positives = 90/197 (45%), Gaps = 3/197 (1%)
Frame = +3
Query: 105 GRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHSA 284
G +VTG SGIG+ K+GA + R + +Q K + N +
Sbjct: 32 GAHVVVTGGSSGIGKCIAIECYKQGAFITLVARNEDKLLQAKKEIEMHS--INDKQVVLC 89
Query: 285 VELDVSNSKAVQDLVQDTLKQYKK---PPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNL 455
+ +DVS + V++ +KQ ++ P ++VN AG+ L ++ ++++N
Sbjct: 90 ISVDVSQD---YNQVENVIKQAQEKLGPVDMLVNCAGMAVSGKFEDLEVSTFERLMSINY 146
Query: 456 KGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELG 635
G+ +A M E V G I+ +SS G+ G G T Y++SK + + ++ E+
Sbjct: 147 LGSVYPSRAVITTMKERRV-GRIVFVSSQAGQLGLFGFTAYSASKFAIRGLAEALQMEVK 205
Query: 636 KFNIRVNAILPGFIDTP 686
+N+ + P DTP
Sbjct: 206 PYNVYITVAYPPDTDTP 222
>U43559-1|AAC50725.1| 318|Homo sapiens 11-cis retinol dehydrogenase
protein.
Length = 318
Score = 65.7 bits (153), Expect = 2e-10
Identities = 53/192 (27%), Positives = 91/192 (47%), Gaps = 2/192 (1%)
Frame = +3
Query: 120 VTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHSAVELDV 299
+TG SG GR L + G V+A+ A + ++ H+ + LD+
Sbjct: 33 ITGCDSGFGRLLALQLDQRGFRVLASCLTPSGAEDLQRVASSRL--------HTTL-LDI 83
Query: 300 SNSKAVQDLVQDTLKQYKKPPCI-IVNSAGITRDNWMLK-LSEEDYDSVLNVNLKGTFLV 473
++ ++VQ + K+ +VN+AG+ L+ +D+ VLNVN G V
Sbjct: 84 TDPQSVQQAAKWVEMHVKEAGLFGLVNNAGVAGIIGPTPWLTRDDFQRVLNVNTMGPIGV 143
Query: 474 MQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELGKFNIRV 653
A + ++ G +INI+S++G+ G Y SK G+ A + S +++ F IRV
Sbjct: 144 TLALLPLLQQAR--GRVINITSVLGRLAANGG-GYCVSKFGLEAFSDSLRRDVAHFGIRV 200
Query: 654 NAILPGFIDTPI 689
+ + PGF TP+
Sbjct: 201 SIVEPGFFRTPV 212
>AF037062-1|AAC09250.1| 318|Homo sapiens retinol dehydrogenase
protein.
Length = 318
Score = 65.7 bits (153), Expect = 2e-10
Identities = 53/192 (27%), Positives = 91/192 (47%), Gaps = 2/192 (1%)
Frame = +3
Query: 120 VTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHSAVELDV 299
+TG SG GR L + G V+A+ A + ++ H+ + LD+
Sbjct: 33 ITGCDSGFGRLLALQLDQRGFRVLASCLTPSGAEDLQRVASSRL--------HTTL-LDI 83
Query: 300 SNSKAVQDLVQDTLKQYKKPPCI-IVNSAGITRDNWMLK-LSEEDYDSVLNVNLKGTFLV 473
++ ++VQ + K+ +VN+AG+ L+ +D+ VLNVN G V
Sbjct: 84 TDPQSVQQAAKWVEMHVKEAGLFGLVNNAGVAGIIGPTPWLTRDDFQRVLNVNTMGPIGV 143
Query: 474 MQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELGKFNIRV 653
A + ++ G +INI+S++G+ G Y SK G+ A + S +++ F IRV
Sbjct: 144 TLALLPLLQQAR--GRVINITSVLGRLAANGG-GYCVSKFGLEAFSDSLRRDVAHFGIRV 200
Query: 654 NAILPGFIDTPI 689
+ + PGF TP+
Sbjct: 201 SIVEPGFFRTPV 212
>AB083038-1|BAB91014.1| 309|Homo sapiens retinal short chain
dehydrogenase reductase protein.
Length = 309
Score = 65.3 bits (152), Expect = 2e-10
Identities = 55/198 (27%), Positives = 83/198 (41%), Gaps = 3/198 (1%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEH 278
V G + L+TGAGSG+GR ++ G+ ++ D E +T K G
Sbjct: 38 VAGEIVLITGAGSGLGRLLALQFARLGSVLVLWDINKEGNEETCKMAREA-----GATRV 92
Query: 279 SAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLK 458
A D S + V V D +K+ I++N+AGI L +E + +VN K
Sbjct: 93 RAYTCDCSQKEGVY-RVADQVKKEIGDVSILINNAGIVTGKKFLDCPDELMEKSFDVNFK 151
Query: 459 GTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKEL-- 632
+AF AM + G ++ ISS G G G +Y +SK +S E
Sbjct: 152 AHLWTYKAFLPAMIAND-HGHLVCISSSAGLSGVNGLADYCASKFAAFGFAESVFVETFV 210
Query: 633 -GKFNIRVNAILPGFIDT 683
+ I+ + P FI T
Sbjct: 211 QKQKGIKTTIVCPFFIKT 228
>AY358473-1|AAQ88837.1| 331|Homo sapiens RDH13 protein.
Length = 331
Score = 64.9 bits (151), Expect = 3e-10
Identities = 56/214 (26%), Positives = 103/214 (48%), Gaps = 17/214 (7%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADR---KYEAAVQTIKTHTALAPGTNGG 269
+ G+ +VTGA +GIG+ L++ G +I A R K EAA + I+ T
Sbjct: 36 IPGKTVIVTGANTGIGKQTALELARRGGNIILACRDMEKCEAAAKDIRGETL-------N 88
Query: 270 EEHSAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITR-DNWMLKLSEEDYDSVLN 446
+A LD+++ K++++ +++ ++ I++N+AG+ R +W +E+ ++
Sbjct: 89 HHVNARHLDLASLKSIREFAAKIIEEEERVD-ILINNAGVMRCPHW---TTEDGFEMQFG 144
Query: 447 VNLKGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMG------QTN-------YASS 587
VN G FL+ + ++S IIN+SS+ G++ QT Y S
Sbjct: 145 VNHLGHFLLTNLLLDKL-KASAPSRIINLSSLAHVAGHIDFDDLNWQTRKYNTKAAYCQS 203
Query: 588 KAGVVAMTQSAAKELGKFNIRVNAILPGFIDTPI 689
K +V T+ ++ L + VNA+ PG T +
Sbjct: 204 KLAIVLFTKELSRRLQGSGVTVNALHPGVARTEL 237
>AL023881-4|CAI95592.1| 280|Homo sapiens 2,4-dienoyl CoA reductase
2, peroxisomal protein.
Length = 280
Score = 64.9 bits (151), Expect = 3e-10
Identities = 57/195 (29%), Positives = 90/195 (46%), Gaps = 3/195 (1%)
Frame = +3
Query: 96 LVVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEE 275
L+ ++A +TG GSGIG ++ + G A RK A G
Sbjct: 25 LLRDKVAFITGGGSGIGFRIAEIFMRHGCHTAA--RKLAGAT---------------GRR 67
Query: 276 HSAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLK---LSEEDYDSVLN 446
+ +DV AV V LK++ + +I +AG N++ LS + +V++
Sbjct: 68 CLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCAAG----NFLCPAGALSFNAFKTVMD 123
Query: 447 VNLKGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAK 626
++ GTF V + + G I+NI++ +G G Q + S+KA V AMT+ A
Sbjct: 124 IDTSGTFNVSRVLYEKFFRDH-GGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAV 182
Query: 627 ELGKFNIRVNAILPG 671
E G NIRVN++ PG
Sbjct: 183 EWGPQNIRVNSLAPG 197
>BC000663-1|AAH00663.2| 230|Homo sapiens dehydrogenase/reductase
(SDR family) member 4 like 2 protein.
Length = 230
Score = 64.5 bits (150), Expect = 4e-10
Identities = 50/188 (26%), Positives = 90/188 (47%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEH 278
+ ++ALVT + GIG A + L+++ A V+ + RK + Q + T G H
Sbjct: 28 LTNKVALVTASTDGIGFAIARRLAQDRAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCH 87
Query: 279 SAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLK 458
V ++ + LV +K + ++ N+A ++ ++EE +D L++N+K
Sbjct: 88 ------VGKAEDRERLVAMAVKLHGGIDILVSNAAVNPFFGSLMDVTEEVWDKTLDINVK 141
Query: 459 GTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELGK 638
L+ +A M E GS++ +SSI + G + Y SK ++ + + A EL
Sbjct: 142 APALMTKAVVPEM-EKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLNNTLAIELAP 200
Query: 639 FNIRVNAI 662
NIRVN +
Sbjct: 201 RNIRVNCL 208
>AK057667-1|BAB71545.1| 231|Homo sapiens protein ( Homo sapiens
cDNA FLJ33105 fis, clone TRACH2000926, weakly similar to
PROBABLE OXIDOREDUCTASE EPHD (EC 1.-.-.-). ).
Length = 231
Score = 64.5 bits (150), Expect = 4e-10
Identities = 51/177 (28%), Positives = 77/177 (43%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEH 278
V G + L+TGAGSG+GR ++ G+ ++ D E +T K +A H
Sbjct: 38 VAGEIVLITGAGSGLGRLLALQFARLGSVLVLWDINKEGNEETCK----MAREAGATRVH 93
Query: 279 SAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLK 458
A D S + V V D +K+ I++N+AGI L +E + +VN K
Sbjct: 94 -AYTCDCSQKEGVY-RVADQVKKEVGDVSILINNAGIVTGKKFLDCPDELMEKSFDVNFK 151
Query: 459 GTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKE 629
+AF AM + G ++ ISS G G G +Y +SK +S E
Sbjct: 152 AHLWTYKAFLPAMIAND-HGHLVCISSSAGLSGVNGLADYCASKFAAFGFAESVFVE 207
>BC008650-1|AAH08650.1| 300|Homo sapiens HSD17B11 protein protein.
Length = 300
Score = 62.9 bits (146), Expect = 1e-09
Identities = 52/211 (24%), Positives = 89/211 (42%), Gaps = 3/211 (1%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEH 278
V G + L+TGAG GIGR +K + ++ D +T L G + H
Sbjct: 34 VTGEIVLITGAGHGIGRLTAYEFAKLKSKLVLWDINKHGLEETAAKCKGL-----GAKVH 88
Query: 279 SAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLK 458
+ V +D SN + + ++ K I+VN+AG+ + + + + VN+
Sbjct: 89 TFV-VDCSNREDIYSSAKN-CKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVL 146
Query: 459 GTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELGK 638
F +AF AM +++ G I+ ++S G Y SSK V ++ EL
Sbjct: 147 AHFWTTKAFLPAMTKNN-HGHIVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDELAA 205
Query: 639 FNI---RVNAILPGFIDTPIIKTVPDKVKET 722
I + + P F++T IK + + T
Sbjct: 206 LQITGVKTTCLCPNFVNTGFIKKMSTSLGPT 236
>AK075392-1|BAC11591.1| 331|Homo sapiens protein ( Homo sapiens
cDNA PSEC0082 fis, clone NT2RP2004966, highly similar to
Retinol dehydrogenase 13 (EC 1.1.1.-). ).
Length = 331
Score = 62.9 bits (146), Expect = 1e-09
Identities = 56/214 (26%), Positives = 102/214 (47%), Gaps = 17/214 (7%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADR---KYEAAVQTIKTHTALAPGTNGG 269
+ G+ +VTGA +GIG+ L++ G +I A R K EAA + I+ T
Sbjct: 36 IPGKTVIVTGANTGIGKQTALELARRGGNIILACRDMEKCEAAAKDIRGETL-------N 88
Query: 270 EEHSAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITR-DNWMLKLSEEDYDSVLN 446
+A LD+++ K+++ +++ ++ I++N+AG+ R +W +E+ ++
Sbjct: 89 HHVNARHLDLASLKSIRVFAAKIIEEEERVD-ILINNAGVMRCPHW---TTEDGFEMQFG 144
Query: 447 VNLKGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMG------QTN-------YASS 587
VN G FL+ + ++S IIN+SS+ G++ QT Y S
Sbjct: 145 VNHLGHFLLTNLLLDKL-KASAPSRIINLSSLAHVAGHIDFDDLNWQTRKYNTKAAYCQS 203
Query: 588 KAGVVAMTQSAAKELGKFNIRVNAILPGFIDTPI 689
K +V T+ ++ L + VNA+ PG T +
Sbjct: 204 KLAIVLFTKELSRRLQGSGVTVNALHPGVARTEL 237
>CR457309-1|CAG33590.1| 173|Homo sapiens DHRS6 protein.
Length = 173
Score = 62.5 bits (145), Expect = 2e-09
Identities = 48/178 (26%), Positives = 89/178 (50%), Gaps = 1/178 (0%)
Frame = +3
Query: 93 GLVVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGE 272
G + G++ ++T A GIG+AA ++EGA VIA D E+ +Q ++ + PG
Sbjct: 2 GRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDIN-ESKLQELEKY----PGI---- 52
Query: 273 EHSAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVN 452
LDV+ K + + + ++ N AG +L E+D+D +N+N
Sbjct: 53 --QTRVLDVTKKKQIDQFASEVERL-----DVLFNVAGFVHHGTVLDCEEKDWDFSMNLN 105
Query: 453 LKGTFLVMQAF-AKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAA 623
++ +L+++AF K +A+ S G+IIN+SS+ G ++ + + +S+A
Sbjct: 106 VRSMYLMIKAFLPKMLAQKS--GNIINMSSVASSVKG-GSVSFRGLRCSYTHIIKSSA 160
>BC037277-1|AAH37277.1| 173|Homo sapiens BDH2 protein protein.
Length = 173
Score = 62.5 bits (145), Expect = 2e-09
Identities = 48/178 (26%), Positives = 89/178 (50%), Gaps = 1/178 (0%)
Frame = +3
Query: 93 GLVVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGE 272
G + G++ ++T A GIG+AA ++EGA VIA D E+ +Q ++ + PG
Sbjct: 2 GRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDIN-ESKLQELEKY----PGI---- 52
Query: 273 EHSAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVN 452
LDV+ K + + + ++ N AG +L E+D+D +N+N
Sbjct: 53 --QTRVLDVTKKKQIDQFANEVERL-----DVLFNVAGFVHHGTVLDCEEKDWDFSMNLN 105
Query: 453 LKGTFLVMQAF-AKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAA 623
++ +L+++AF K +A+ S G+IIN+SS+ G ++ + + +S+A
Sbjct: 106 VRSMYLMIKAFLPKMLAQKS--GNIINMSSVASSVKG-GSVSFRGLRCSYTHIIKSSA 160
>BC036001-1|AAH36001.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 11 protein.
Length = 300
Score = 62.5 bits (145), Expect = 2e-09
Identities = 51/202 (25%), Positives = 86/202 (42%), Gaps = 3/202 (1%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEH 278
V G + L+TGAG GIGR +K + ++ D +T L G + H
Sbjct: 34 VTGEIVLITGAGHGIGRLTAYEFAKLKSKLVLWDINKHGLEETAAKCKGL-----GAKVH 88
Query: 279 SAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLK 458
+ V +D SN + + + +K I+VN+AG+ + + + + VN+
Sbjct: 89 TFV-VDCSNREDIYSSAK-KVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVL 146
Query: 459 GTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELGK 638
F +AF AM +++ G I+ ++S G Y SSK V ++ EL
Sbjct: 147 AHFWTTKAFLPAMTKNN-HGHIVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDELAA 205
Query: 639 FNI---RVNAILPGFIDTPIIK 695
I + + P F++T IK
Sbjct: 206 LQITGVKTTCLCPNFVNTGFIK 227
>BC021673-1|AAH21673.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 11 protein.
Length = 300
Score = 62.5 bits (145), Expect = 2e-09
Identities = 51/202 (25%), Positives = 86/202 (42%), Gaps = 3/202 (1%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEH 278
V G + L+TGAG GIGR +K + ++ D +T L G + H
Sbjct: 34 VTGEIVLITGAGHGIGRLTAYEFAKLKSKLVLWDINKHGLEETAAKCKGL-----GAKVH 88
Query: 279 SAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLK 458
+ V +D SN + + + +K I+VN+AG+ + + + + VN+
Sbjct: 89 TFV-VDCSNREDIYSSAK-KVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVL 146
Query: 459 GTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELGK 638
F +AF AM +++ G I+ ++S G Y SSK V ++ EL
Sbjct: 147 AHFWTTKAFLPAMTKNN-HGHIVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDELAA 205
Query: 639 FNI---RVNAILPGFIDTPIIK 695
I + + P F++T IK
Sbjct: 206 LQITGVKTTCLCPNFVNTGFIK 227
>BC016367-1|AAH16367.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 11 protein.
Length = 300
Score = 62.5 bits (145), Expect = 2e-09
Identities = 51/202 (25%), Positives = 86/202 (42%), Gaps = 3/202 (1%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEH 278
V G + L+TGAG GIGR +K + ++ D +T L G + H
Sbjct: 34 VTGEIVLITGAGHGIGRLTAYEFAKLKSKLVLWDINKHGLEETAAKCKGL-----GAKVH 88
Query: 279 SAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLK 458
+ V +D SN + + + +K I+VN+AG+ + + + + VN+
Sbjct: 89 TFV-VDCSNREDIYSSAK-KVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVL 146
Query: 459 GTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELGK 638
F +AF AM +++ G I+ ++S G Y SSK V ++ EL
Sbjct: 147 AHFWTTKAFLPAMTKNN-HGHIVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDELAA 205
Query: 639 FNI---RVNAILPGFIDTPIIK 695
I + + P F++T IK
Sbjct: 206 LQITGVKTTCLCPNFVNTGFIK 227
>BC014327-1|AAH14327.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 11 protein.
Length = 300
Score = 62.5 bits (145), Expect = 2e-09
Identities = 51/202 (25%), Positives = 86/202 (42%), Gaps = 3/202 (1%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEH 278
V G + L+TGAG GIGR +K + ++ D +T L G + H
Sbjct: 34 VTGEIVLITGAGHGIGRLTAYEFAKLKSKLVLWDINKHGLEETAAKCKGL-----GAKVH 88
Query: 279 SAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLK 458
+ V +D SN + + + +K I+VN+AG+ + + + + VN+
Sbjct: 89 TFV-VDCSNREDIYSSAK-KVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVL 146
Query: 459 GTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELGK 638
F +AF AM +++ G I+ ++S G Y SSK V ++ EL
Sbjct: 147 AHFWTTKAFLPAMTKNN-HGHIVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDELAA 205
Query: 639 FNI---RVNAILPGFIDTPIIK 695
I + + P F++T IK
Sbjct: 206 LQITGVKTTCLCPNFVNTGFIK 227
>AY358553-1|AAQ88917.1| 300|Homo sapiens KFLL207 protein.
Length = 300
Score = 62.5 bits (145), Expect = 2e-09
Identities = 51/202 (25%), Positives = 86/202 (42%), Gaps = 3/202 (1%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEH 278
V G + L+TGAG GIGR +K + ++ D +T L G + H
Sbjct: 34 VTGEIVLITGAGHGIGRLTAYEFAKLKSKLVLWDINKHGLEETAAKCKGL-----GAKVH 88
Query: 279 SAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLK 458
+ V +D SN + + + +K I+VN+AG+ + + + + VN+
Sbjct: 89 TFV-VDCSNREDIYSSAK-KVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVL 146
Query: 459 GTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELGK 638
F +AF AM +++ G I+ ++S G Y SSK V ++ EL
Sbjct: 147 AHFWTTKAFLPAMTKNN-HGHIVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDELAA 205
Query: 639 FNI---RVNAILPGFIDTPIIK 695
I + + P F++T IK
Sbjct: 206 LQITGVKTTCLCPNFVNTGFIK 227
>AK023323-1|BAB14526.1| 173|Homo sapiens protein ( Homo sapiens
cDNA FLJ13261 fis, clone OVARC1000885, weakly similar to
OXIDOREDUCTASE UCPA (EC 1.-.-.-). ).
Length = 173
Score = 62.5 bits (145), Expect = 2e-09
Identities = 48/178 (26%), Positives = 89/178 (50%), Gaps = 1/178 (0%)
Frame = +3
Query: 93 GLVVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGE 272
G + G++ ++T A GIG+AA ++EGA VIA D E+ +Q ++ + PG
Sbjct: 2 GRLDGKVIILTAAAQGIGQAAALAFAREGAKVIATDIN-ESKLQELEKY----PGI---- 52
Query: 273 EHSAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVN 452
LDV+ K + + + ++ N AG +L E+D+D +N+N
Sbjct: 53 --QTRVLDVTKKKQIDQFANEVERL-----DVLFNVAGFVHHGTVLDCEEKDWDFSMNLN 105
Query: 453 LKGTFLVMQAF-AKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAA 623
++ +L+++AF K +A+ S G+IIN+SS+ G ++ + + +S+A
Sbjct: 106 VRSMYLMIKAFLPKMLAQKS--GNIINMSSVASSVKG-GSVSFRGLRCSYTHIIKSSA 160
>AF273056-1|AAM44459.1| 300|Homo sapiens CTCL tumor antigen
HD-CL-03 protein.
Length = 300
Score = 62.5 bits (145), Expect = 2e-09
Identities = 51/202 (25%), Positives = 86/202 (42%), Gaps = 3/202 (1%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEH 278
V G + L+TGAG GIGR +K + ++ D +T L G + H
Sbjct: 34 VTGEIVLITGAGHGIGRLTAYEFAKLKSKLVLWDINKHGLEETAAKCKGL-----GAKVH 88
Query: 279 SAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLK 458
+ V +D SN + + + +K I+VN+AG+ + + + + VN+
Sbjct: 89 TFV-VDCSNREDIYSSAK-KVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVL 146
Query: 459 GTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELGK 638
F +AF AM +++ G I+ ++S G Y SSK V ++ EL
Sbjct: 147 AHFWTTKAFLPAMTKNN-HGHIVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDELAA 205
Query: 639 FNI---RVNAILPGFIDTPIIK 695
I + + P F++T IK
Sbjct: 206 LQITGVKTTCLCPNFVNTGFIK 227
>AF126780-1|AAF06939.1| 300|Homo sapiens retinal short-chain
dehydrogenase/reductase retSDR2 protein.
Length = 300
Score = 62.5 bits (145), Expect = 2e-09
Identities = 51/202 (25%), Positives = 86/202 (42%), Gaps = 3/202 (1%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEH 278
V G + L+TGAG GIGR +K + ++ D +T L G + H
Sbjct: 34 VTGEIVLITGAGHGIGRLTAYEFAKLKSKLVLWDINKHGLEETAAKCKGL-----GAKVH 88
Query: 279 SAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLK 458
+ V +D SN + + + +K I+VN+AG+ + + + + VN+
Sbjct: 89 TFV-VDCSNREDIYSSAK-KVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVL 146
Query: 459 GTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELGK 638
F +AF AM +++ G I+ ++S G Y SSK V ++ EL
Sbjct: 147 AHFWTTKAFLPAMTKNN-HGHIVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDELAA 205
Query: 639 FNI---RVNAILPGFIDTPIIK 695
I + + P F++T IK
Sbjct: 206 LQITGVKTTCLCPNFVNTGFIK 227
>L40802-1|AAC41917.1| 387|Homo sapiens 17-hydroxysteroid
dehydrogenase protein.
Length = 387
Score = 61.3 bits (142), Expect = 4e-09
Identities = 57/213 (26%), Positives = 96/213 (45%), Gaps = 4/213 (1%)
Frame = +3
Query: 108 RLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHSAV 287
+ LVTG G+G A C+ L + G TV A E + +P S +
Sbjct: 83 KAVLVTGGDCGLGHALCKYLDELGFTVFAGVLN-ENGPGAEELRRTCSPRL------SVL 135
Query: 288 ELDVSNSKAVQDLVQDTLKQYK-KPPCIIVNSAGIT---RDNWMLKLSEEDYDSVLNVNL 455
++D++ ++D + + ++N+AG+ D +L ++ DY + VN
Sbjct: 136 QMDITKPVQIKDAYSKVAAMLQDRGLWAVINNAGVLGFPTDGELLLMT--DYKQCMAVNF 193
Query: 456 KGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELG 635
GT V + F + +S G ++N+SS+ G +Y SSKA V + EL
Sbjct: 194 FGTVEVTKTFLPLLRKSK--GRLVNVSSMGGGAPMERLASYGSSKAAVTMFSSVMRLELS 251
Query: 636 KFNIRVNAILPGFIDTPIIKTVPDKVKETDCEI 734
K+ I+V +I PG T I T DK ++ + +I
Sbjct: 252 KWGIKVASIQPGGFLTNIAGT-SDKWEKLEKDI 283
>L11708-1|AAA03562.1| 387|Homo sapiens 17 beta hydroxysteroid
dehydrogenase type 2 protein.
Length = 387
Score = 61.3 bits (142), Expect = 4e-09
Identities = 57/213 (26%), Positives = 96/213 (45%), Gaps = 4/213 (1%)
Frame = +3
Query: 108 RLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHSAV 287
+ LVTG G+G A C+ L + G TV A E + +P S +
Sbjct: 83 KAVLVTGGDCGLGHALCKYLDELGFTVFAGVLN-ENGPGAEELRRTCSPRL------SVL 135
Query: 288 ELDVSNSKAVQDLVQDTLKQYK-KPPCIIVNSAGIT---RDNWMLKLSEEDYDSVLNVNL 455
++D++ ++D + + ++N+AG+ D +L ++ DY + VN
Sbjct: 136 QMDITKPVQIKDAYSKVAAMLQDRGLWAVINNAGVLGFPTDGELLLMT--DYKQCMAVNF 193
Query: 456 KGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELG 635
GT V + F + +S G ++N+SS+ G +Y SSKA V + EL
Sbjct: 194 FGTVEVTKTFLPLLRKSK--GRLVNVSSMGGGAPMERLASYGSSKAAVTMFSSVMRLELS 251
Query: 636 KFNIRVNAILPGFIDTPIIKTVPDKVKETDCEI 734
K+ I+V +I PG T I T DK ++ + +I
Sbjct: 252 KWGIKVASIQPGGFLTNIAGT-SDKWEKLEKDI 283
>CR457180-1|CAG33461.1| 318|Homo sapiens RDH11 protein.
Length = 318
Score = 61.3 bits (142), Expect = 4e-09
Identities = 49/209 (23%), Positives = 98/209 (46%), Gaps = 12/209 (5%)
Frame = +3
Query: 105 GRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHSA 284
G++ +VTGA +GIG+ + L++ GA V A R E K T G ++
Sbjct: 41 GKVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKE----IQTTTGNQQVLV 96
Query: 285 VELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLKGT 464
+LD+S++K+++ + L + +K +++N+AG+ + + + ++ + VN G
Sbjct: 97 RKLDLSDTKSIRAFAKGFLAE-EKHLHVLINNAGVMMCPY--SKTADGFEMHIGVNHLGH 153
Query: 465 FLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTN------------YASSKAGVVAM 608
FL+ + + ES+ I+N+SS+ G + N Y SK +
Sbjct: 154 FLLTHLLLEKLKESA-PSRIVNVSSLAHHLGRIHFHNLQGEKFYNAGLAYCHSKLANILF 212
Query: 609 TQSAAKELGKFNIRVNAILPGFIDTPIIK 695
TQ A+ L + ++ PG + + +++
Sbjct: 213 TQELARRLKGSGVTTYSVHPGTVQSELVR 241
>BC059170-1|AAH59170.1| 387|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 2 protein.
Length = 387
Score = 61.3 bits (142), Expect = 4e-09
Identities = 57/213 (26%), Positives = 96/213 (45%), Gaps = 4/213 (1%)
Frame = +3
Query: 108 RLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHSAV 287
+ LVTG G+G A C+ L + G TV A E + +P S +
Sbjct: 83 KAVLVTGGDCGLGHALCKYLDELGFTVFAGVLN-ENGPGAEELRRTCSPRL------SVL 135
Query: 288 ELDVSNSKAVQDLVQDTLKQYK-KPPCIIVNSAGIT---RDNWMLKLSEEDYDSVLNVNL 455
++D++ ++D + + ++N+AG+ D +L ++ DY + VN
Sbjct: 136 QMDITKPVQIKDAYSKVAAMLQDRGLWAVINNAGVLGFPTDGELLLMT--DYKQCMAVNF 193
Query: 456 KGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELG 635
GT V + F + +S G ++N+SS+ G +Y SSKA V + EL
Sbjct: 194 FGTVEVTKTFLPLLRKSK--GRLVNVSSMGGGAPMERLASYGSSKAAVTMFSSVMRLELS 251
Query: 636 KFNIRVNAILPGFIDTPIIKTVPDKVKETDCEI 734
K+ I+V +I PG T I T DK ++ + +I
Sbjct: 252 KWGIKVASIQPGGFLTNIAGT-SDKWEKLEKDI 283
>BC037302-1|AAH37302.1| 318|Homo sapiens retinol dehydrogenase 11
(all-trans/9-cis/11-cis) protein.
Length = 318
Score = 61.3 bits (142), Expect = 4e-09
Identities = 49/209 (23%), Positives = 98/209 (46%), Gaps = 12/209 (5%)
Frame = +3
Query: 105 GRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHSA 284
G++ +VTGA +GIG+ + L++ GA V A R E K T G ++
Sbjct: 41 GKVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKE----IQTTTGNQQVLV 96
Query: 285 VELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLKGT 464
+LD+S++K+++ + L + +K +++N+AG+ + + + ++ + VN G
Sbjct: 97 RKLDLSDTKSIRAFAKGFLAE-EKHLHVLINNAGVMMCPY--SKTADGFEMHIGVNHLGH 153
Query: 465 FLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTN------------YASSKAGVVAM 608
FL+ + + ES+ I+N+SS+ G + N Y SK +
Sbjct: 154 FLLTHLLLEKLKESA-PSRIVNVSSLAHHLGRIHFHNLQGEKFYNAGLAYCHSKLANILF 212
Query: 609 TQSAAKELGKFNIRVNAILPGFIDTPIIK 695
TQ A+ L + ++ PG + + +++
Sbjct: 213 TQELARRLKGSGVTTYSVHPGTVQSELVR 241
>BC026274-1|AAH26274.1| 318|Homo sapiens retinol dehydrogenase 11
(all-trans/9-cis/11-cis) protein.
Length = 318
Score = 61.3 bits (142), Expect = 4e-09
Identities = 49/209 (23%), Positives = 98/209 (46%), Gaps = 12/209 (5%)
Frame = +3
Query: 105 GRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHSA 284
G++ +VTGA +GIG+ + L++ GA V A R E K T G ++
Sbjct: 41 GKVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKE----IQTTTGNQQVLV 96
Query: 285 VELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLKGT 464
+LD+S++K+++ + L + +K +++N+AG+ + + + ++ + VN G
Sbjct: 97 RKLDLSDTKSIRAFAKGFLAE-EKHLHVLINNAGVMMCPY--SKTADGFEMHIGVNHLGH 153
Query: 465 FLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTN------------YASSKAGVVAM 608
FL+ + + ES+ I+N+SS+ G + N Y SK +
Sbjct: 154 FLLTHLLLEKLKESA-PSRIVNVSSLAHHLGRIHFHNLQGEKFYNAGLAYCHSKLANILF 212
Query: 609 TQSAAKELGKFNIRVNAILPGFIDTPIIK 695
TQ A+ L + ++ PG + + +++
Sbjct: 213 TQELARRLKGSGVTTYSVHPGTVQSELVR 241
>BC011727-1|AAH11727.1| 318|Homo sapiens RDH11 protein protein.
Length = 318
Score = 61.3 bits (142), Expect = 4e-09
Identities = 49/209 (23%), Positives = 98/209 (46%), Gaps = 12/209 (5%)
Frame = +3
Query: 105 GRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHSA 284
G++ +VTGA +GIG+ + L++ GA V A R E K T G ++
Sbjct: 41 GKVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKE----IQTTTGNQQVLV 96
Query: 285 VELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLKGT 464
+LD+S++K+++ + L + +K +++N+AG+ + + + ++ + VN G
Sbjct: 97 RKLDLSDTKSIRAFAKGFLAE-EKHLHVLINNAGVMMCPY--SKTADGFEMHIGVNHLGH 153
Query: 465 FLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTN------------YASSKAGVVAM 608
FL+ + + ES+ I+N+SS+ G + N Y SK +
Sbjct: 154 FLLTHLLLEKLKESA-PSRIVNVSSLAHHLGRIHFHNLQGEKFYNAGLAYCHSKLANILF 212
Query: 609 TQSAAKELGKFNIRVNAILPGFIDTPIIK 695
TQ A+ L + ++ PG + + +++
Sbjct: 213 TQELARRLKGSGVTTYSVHPGTVQSELVR 241
>BC009581-1|AAH09581.1| 387|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 2 protein.
Length = 387
Score = 61.3 bits (142), Expect = 4e-09
Identities = 57/213 (26%), Positives = 96/213 (45%), Gaps = 4/213 (1%)
Frame = +3
Query: 108 RLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHSAV 287
+ LVTG G+G A C+ L + G TV A E + +P S +
Sbjct: 83 KAVLVTGGDCGLGHALCKYLDELGFTVFAGVLN-ENGPGAEELRRTCSPRL------SVL 135
Query: 288 ELDVSNSKAVQDLVQDTLKQYK-KPPCIIVNSAGIT---RDNWMLKLSEEDYDSVLNVNL 455
++D++ ++D + + ++N+AG+ D +L ++ DY + VN
Sbjct: 136 QMDITKPVQIKDAYSKVAAMLQDRGLWAVINNAGVLGFPTDGELLLMT--DYKQCMAVNF 193
Query: 456 KGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELG 635
GT V + F + +S G ++N+SS+ G +Y SSKA V + EL
Sbjct: 194 FGTVEVTKTFLPLLRKSK--GRLVNVSSMGGGAPMERLASYGSSKAAVTMFSSVMRLELS 251
Query: 636 KFNIRVNAILPGFIDTPIIKTVPDKVKETDCEI 734
K+ I+V +I PG T I T DK ++ + +I
Sbjct: 252 KWGIKVASIQPGGFLTNIAGT-SDKWEKLEKDI 283
>BC000112-1|AAH00112.1| 318|Homo sapiens retinol dehydrogenase 11
(all-trans/9-cis/11-cis) protein.
Length = 318
Score = 61.3 bits (142), Expect = 4e-09
Identities = 49/209 (23%), Positives = 98/209 (46%), Gaps = 12/209 (5%)
Frame = +3
Query: 105 GRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHSA 284
G++ +VTGA +GIG+ + L++ GA V A R E K T G ++
Sbjct: 41 GKVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKE----IQTTTGNQQVLV 96
Query: 285 VELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLKGT 464
+LD+S++K+++ + L + +K +++N+AG+ + + + ++ + VN G
Sbjct: 97 RKLDLSDTKSIRAFAKGFLAE-EKHLHVLINNAGVMMCPY--SKTADGFEMHIGVNHLGH 153
Query: 465 FLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTN------------YASSKAGVVAM 608
FL+ + + ES+ I+N+SS+ G + N Y SK +
Sbjct: 154 FLLTHLLLEKLKESA-PSRIVNVSSLAHHLGRIHFHNLQGEKFYNAGLAYCHSKLANILF 212
Query: 609 TQSAAKELGKFNIRVNAILPGFIDTPIIK 695
TQ A+ L + ++ PG + + +++
Sbjct: 213 TQELARRLKGSGVTTYSVHPGTVQSELVR 241
>AY325910-1|AAP78485.1| 387|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 2 protein.
Length = 387
Score = 61.3 bits (142), Expect = 4e-09
Identities = 57/213 (26%), Positives = 96/213 (45%), Gaps = 4/213 (1%)
Frame = +3
Query: 108 RLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHSAV 287
+ LVTG G+G A C+ L + G TV A E + +P S +
Sbjct: 83 KAVLVTGGDCGLGHALCKYLDELGFTVFAGVLN-ENGPGAEELRRTCSPRL------SVL 135
Query: 288 ELDVSNSKAVQDLVQDTLKQYK-KPPCIIVNSAGIT---RDNWMLKLSEEDYDSVLNVNL 455
++D++ ++D + + ++N+AG+ D +L ++ DY + VN
Sbjct: 136 QMDITKPVQIKDAYSKVAAMLQDRGLWAVINNAGVLGFPTDGELLLMT--DYKQCMAVNF 193
Query: 456 KGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELG 635
GT V + F + +S G ++N+SS+ G +Y SSKA V + EL
Sbjct: 194 FGTVEVTKTFLPLLRKSK--GRLVNVSSMGGGAPMERLASYGSSKAAVTMFSSVMRLELS 251
Query: 636 KFNIRVNAILPGFIDTPIIKTVPDKVKETDCEI 734
K+ I+V +I PG T I T DK ++ + +I
Sbjct: 252 KWGIKVASIQPGGFLTNIAGT-SDKWEKLEKDI 283
>AK223001-1|BAD96721.1| 387|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 2 variant protein.
Length = 387
Score = 61.3 bits (142), Expect = 4e-09
Identities = 57/213 (26%), Positives = 96/213 (45%), Gaps = 4/213 (1%)
Frame = +3
Query: 108 RLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHSAV 287
+ LVTG G+G A C+ L + G TV A E + +P S +
Sbjct: 83 KAVLVTGGDCGLGHALCKYLDELGFTVFAGVLN-ENGPGAEELRRTCSPRL------SVL 135
Query: 288 ELDVSNSKAVQDLVQDTLKQYK-KPPCIIVNSAGIT---RDNWMLKLSEEDYDSVLNVNL 455
++D++ ++D + + ++N+AG+ D +L ++ DY + VN
Sbjct: 136 QMDITKPVQIKDAYSKVAAMLQDRGLWAVINNAGVLGFPTDGELLLMT--DYKQCMAVNF 193
Query: 456 KGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELG 635
GT V + F + +S G ++N+SS+ G +Y SSKA V + EL
Sbjct: 194 FGTVEVTKTFLPLLRKSK--GRLVNVSSMGGGAPMERLASYGSSKAAVTMFSSVMRLELS 251
Query: 636 KFNIRVNAILPGFIDTPIIKTVPDKVKETDCEI 734
K+ I+V +I PG T I T DK ++ + +I
Sbjct: 252 KWGIKVASIQPGGFLTNIAGT-SDKWEKLEKDI 283
>AK075348-1|BAC11560.1| 300|Homo sapiens protein ( Homo sapiens
cDNA PSEC0029 fis, clone NT2RP1000544, highly similar to
Retinal short-chain dehydrogenase/reductase 2. ).
Length = 300
Score = 61.3 bits (142), Expect = 4e-09
Identities = 51/202 (25%), Positives = 85/202 (42%), Gaps = 3/202 (1%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEH 278
V G L+TGAG GIGR +K + ++ D +T L G + H
Sbjct: 34 VTGETVLITGAGHGIGRLTAYEFAKLKSKLVLWDINKHGLEETAAKCKGL-----GAKVH 88
Query: 279 SAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLK 458
+ V +D SN + + + +K I+VN+AG+ + + + + VN+
Sbjct: 89 TFV-VDCSNREDIYSSAK-KVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVL 146
Query: 459 GTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELGK 638
F +AF AM +++ G I+ ++S G Y SSK V ++ EL
Sbjct: 147 AHFWTTKAFLPAMTKNN-HGHIVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDELAA 205
Query: 639 FNI---RVNAILPGFIDTPIIK 695
I + + P F++T IK
Sbjct: 206 LQITGVKTTCLCPNFVNTGFIK 227
>AF395068-1|AAK72049.1| 318|Homo sapiens HCV core-binding protein
HCBP12 protein.
Length = 318
Score = 61.3 bits (142), Expect = 4e-09
Identities = 49/209 (23%), Positives = 98/209 (46%), Gaps = 12/209 (5%)
Frame = +3
Query: 105 GRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHSA 284
G++ +VTGA +GIG+ + L++ GA V A R E K T G ++
Sbjct: 41 GKVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKE----IQTTTGNQQVLV 96
Query: 285 VELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLKGT 464
+LD+S++K+++ + L + +K +++N+AG+ + + + ++ + VN G
Sbjct: 97 RKLDLSDTKSIRAFAKGFLAE-EKHLHVLINNAGVMMCPY--SKTADGFEMHIGVNHLGH 153
Query: 465 FLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTN------------YASSKAGVVAM 608
FL+ + + ES+ I+N+SS+ G + N Y SK +
Sbjct: 154 FLLTHLLLEKLKESA-PSRIVNVSSLAHHLGRIHFHNLQGEKFYNAGLAYCHSKLANILF 212
Query: 609 TQSAAKELGKFNIRVNAILPGFIDTPIIK 695
TQ A+ L + ++ PG + + +++
Sbjct: 213 TQELARRLKGSGVTTYSVHPGTVQSELVR 241
>AF167438-1|AAF89632.1| 318|Homo sapiens androgen-regulated
short-chain dehydrogenase/reductase 1 protein.
Length = 318
Score = 61.3 bits (142), Expect = 4e-09
Identities = 49/209 (23%), Positives = 98/209 (46%), Gaps = 12/209 (5%)
Frame = +3
Query: 105 GRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHSA 284
G++ +VTGA +GIG+ + L++ GA V A R E K T G ++
Sbjct: 41 GKVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKE----IQTTTGNQQVLV 96
Query: 285 VELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLKGT 464
+LD+S++K+++ + L + +K +++N+AG+ + + + ++ + VN G
Sbjct: 97 RKLDLSDTKSIRAFAKGFLAE-EKHLHVLINNAGVMMCPY--SKTADGFEMHIGVNHLGH 153
Query: 465 FLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTN------------YASSKAGVVAM 608
FL+ + + ES+ I+N+SS+ G + N Y SK +
Sbjct: 154 FLLTHLLLEKLKESA-PSRIVNVSSLAHHLGRIHFHNLQGEKFYNAGLAYCHSKLANILF 212
Query: 609 TQSAAKELGKFNIRVNAILPGFIDTPIIK 695
TQ A+ L + ++ PG + + +++
Sbjct: 213 TQELARRLKGSGVTTYSVHPGTVQSELVR 241
>AF151840-1|AAD34077.1| 318|Homo sapiens CGI-82 protein protein.
Length = 318
Score = 61.3 bits (142), Expect = 4e-09
Identities = 49/209 (23%), Positives = 98/209 (46%), Gaps = 12/209 (5%)
Frame = +3
Query: 105 GRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHSA 284
G++ +VTGA +GIG+ + L++ GA V A R E K T G ++
Sbjct: 41 GKVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKE----IQTTTGNQQVLV 96
Query: 285 VELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLKGT 464
+LD+S++K+++ + L + +K +++N+AG+ + + + ++ + VN G
Sbjct: 97 RKLDLSDTKSIRAFAKGFLAE-EKHLHVLINNAGVMMCPY--SKTADGFEMHIGVNHLGH 153
Query: 465 FLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTN------------YASSKAGVVAM 608
FL+ + + ES+ I+N+SS+ G + N Y SK +
Sbjct: 154 FLLTHLLLEKLKESA-PSRIVNVSSLAHHLGRIHFHNLQGEKFYNAGLAYCHSKLANILF 212
Query: 609 TQSAAKELGKFNIRVNAILPGFIDTPIIK 695
TQ A+ L + ++ PG + + +++
Sbjct: 213 TQELARRLKGSGVTTYSVHPGTVQSELVR 241
>AF086735-1|AAC72923.1| 317|Homo sapiens retinol dehydrogenase
protein.
Length = 317
Score = 61.3 bits (142), Expect = 4e-09
Identities = 59/226 (26%), Positives = 105/226 (46%), Gaps = 5/226 (2%)
Frame = +3
Query: 27 ILLLRFCEFYTIF*IIQDNMVSGLVVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRK 206
+ L F Y + ++ V + + +TG SG G+ + L G V+AA
Sbjct: 3 LYLAVFVGLYYLLHWYRERQVLSHLRDKYVFITGCDSGFGKLLARQLDARGLRVLAACLT 62
Query: 207 YEAAVQTIKTHTALAPGTNGGEEHSAVELDVSNSKAVQDLVQDTLKQYKKPPCI--IVNS 380
+ A Q ++ T+ + V LDV+ +++V Q +K+ + + +VN+
Sbjct: 63 EKGAEQ-LRGQTS--------DRLETVTLDVTKTESVAAAAQ-WVKECVRDKGLWGLVNN 112
Query: 381 AGI---TRDNWMLKLSEEDYDSVLNVNLKGTFLVMQAFAKAMAESSVTGSIINISSIVGK 551
AGI T N + L+++D ++L+VNL G V + + G ++N+ S++G+
Sbjct: 113 AGISLPTAPNEL--LTKQDLLTILDVNLLGVIDVTLNLLPLVRRA--RGRVVNVFSVMGR 168
Query: 552 YGNMGQTNYASSKAGVVAMTQSAAKELGKFNIRVNAILPGFIDTPI 689
G Y SK GV A + S +EL F ++V I PG+ T +
Sbjct: 169 VSLFG-GGYCISKYGVEAFSDSLRRELSYFGVKVAMIEPGYFKTAV 213
>BC058883-1|AAH58883.1| 319|Homo sapiens dehydrogenase/reductase
(SDR family) member 9 protein.
Length = 319
Score = 59.7 bits (138), Expect = 1e-08
Identities = 58/206 (28%), Positives = 90/206 (43%), Gaps = 5/206 (2%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEH 278
+ + +TG SG G A + K+G VI AA T TAL T+ E
Sbjct: 27 ITDKYIFITGCDSGFGNLAARTFDKKGFHVI-------AACLTESGSTALKAETS--ERL 77
Query: 279 SAVELDVSNSKAVQDLVQDTLKQY-KKPPCIIVNSAGI----TRDNWMLKLSEEDYDSVL 443
V LDV++ + V+ Q Q +K ++N+AG+ +W L+ EDY +
Sbjct: 78 RTVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDW---LTLEDYREPI 134
Query: 444 NVNLKGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAA 623
VNL G V + ++ G +IN+SS+ G+ +G Y SK V S
Sbjct: 135 EVNLFGLISVTLNMLPLVKKAQ--GRVINVSSVGGRLAIVG-GGYTPSKYAVEGFNDSLR 191
Query: 624 KELGKFNIRVNAILPGFIDTPIIKTV 701
+++ F + V+ I PG T + V
Sbjct: 192 RDMKAFGVHVSCIEPGLFKTNLADPV 217
>AY359046-1|AAQ89405.1| 319|Homo sapiens RDHL protein.
Length = 319
Score = 59.7 bits (138), Expect = 1e-08
Identities = 58/206 (28%), Positives = 90/206 (43%), Gaps = 5/206 (2%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEH 278
+ + +TG SG G A + K+G VI AA T TAL T+ E
Sbjct: 27 ITDKYIFITGCDSGFGNLAARTFDKKGFHVI-------AACLTESGSTALKAETS--ERL 77
Query: 279 SAVELDVSNSKAVQDLVQDTLKQY-KKPPCIIVNSAGI----TRDNWMLKLSEEDYDSVL 443
V LDV++ + V+ Q Q +K ++N+AG+ +W L+ EDY +
Sbjct: 78 RTVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDW---LTLEDYREPI 134
Query: 444 NVNLKGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAA 623
VNL G V + ++ G +IN+SS+ G+ +G Y SK V S
Sbjct: 135 EVNLFGLISVTLNMLPLVKKAQ--GRVINVSSVGGRLAIVG-GGYTPSKYAVEGFNDSLR 191
Query: 624 KELGKFNIRVNAILPGFIDTPIIKTV 701
+++ F + V+ I PG T + V
Sbjct: 192 RDMKAFGVHVSCIEPGLFKTNLADPV 217
>AY017349-1|AAG49422.1| 319|Homo sapiens retinol dehydrogenase
protein.
Length = 319
Score = 59.7 bits (138), Expect = 1e-08
Identities = 58/206 (28%), Positives = 90/206 (43%), Gaps = 5/206 (2%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEH 278
+ + +TG SG G A + K+G VI AA T TAL T+ E
Sbjct: 27 ITDKYIFITGCDSGFGNLAARTFDKKGFHVI-------AACLTESGSTALKAETS--ERL 77
Query: 279 SAVELDVSNSKAVQDLVQDTLKQY-KKPPCIIVNSAGI----TRDNWMLKLSEEDYDSVL 443
V LDV++ + V+ Q Q +K ++N+AG+ +W L+ EDY +
Sbjct: 78 RTVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDW---LTLEDYREPI 134
Query: 444 NVNLKGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAA 623
VNL G V + ++ G +IN+SS+ G+ +G Y SK V S
Sbjct: 135 EVNLFGLISVTLNMLPLVKKAQ--GRVINVSSVGGRLAIVG-GGYTPSKYAVEGFNDSLR 191
Query: 624 KELGKFNIRVNAILPGFIDTPIIKTV 701
+++ F + V+ I PG T + V
Sbjct: 192 RDMKAFGVHVSCIEPGLFKTNLADPV 217
>AF529288-1|AAN04010.1| 319|Homo sapiens microsomal NADP-dependent
retinol dehydrogenase/reductase transcript A protein.
Length = 319
Score = 59.7 bits (138), Expect = 1e-08
Identities = 58/206 (28%), Positives = 90/206 (43%), Gaps = 5/206 (2%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEH 278
+ + +TG SG G A + K+G VI AA T TAL T+ E
Sbjct: 27 ITDKYIFITGCDSGFGNLAARTFDKKGFHVI-------AACLTESGSTALKAETS--ERL 77
Query: 279 SAVELDVSNSKAVQDLVQDTLKQY-KKPPCIIVNSAGI----TRDNWMLKLSEEDYDSVL 443
V LDV++ + V+ Q Q +K ++N+AG+ +W L+ EDY +
Sbjct: 78 RTVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDW---LTLEDYREPI 134
Query: 444 NVNLKGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAA 623
VNL G V + ++ G +IN+SS+ G+ +G Y SK V S
Sbjct: 135 EVNLFGLISVTLNMLPLVKKAQ--GRVINVSSVGGRLAIVG-GGYTPSKYAVEGFNDSLR 191
Query: 624 KELGKFNIRVNAILPGFIDTPIIKTV 701
+++ F + V+ I PG T + V
Sbjct: 192 RDMKAFGVHVSCIEPGLFKTNLADPV 217
>AF529287-1|AAN04009.1| 319|Homo sapiens microsomal NADP-dependent
retinol dehydrogenase/reductase transcript B protein.
Length = 319
Score = 59.7 bits (138), Expect = 1e-08
Identities = 58/206 (28%), Positives = 90/206 (43%), Gaps = 5/206 (2%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEH 278
+ + +TG SG G A + K+G VI AA T TAL T+ E
Sbjct: 27 ITDKYIFITGCDSGFGNLAARTFDKKGFHVI-------AACLTESGSTALKAETS--ERL 77
Query: 279 SAVELDVSNSKAVQDLVQDTLKQY-KKPPCIIVNSAGI----TRDNWMLKLSEEDYDSVL 443
V LDV++ + V+ Q Q +K ++N+AG+ +W L+ EDY +
Sbjct: 78 RTVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDW---LTLEDYREPI 134
Query: 444 NVNLKGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAA 623
VNL G V + ++ G +IN+SS+ G+ +G Y SK V S
Sbjct: 135 EVNLFGLISVTLNMLPLVKKAQ--GRVINVSSVGGRLAIVG-GGYTPSKYAVEGFNDSLR 191
Query: 624 KELGKFNIRVNAILPGFIDTPIIKTV 701
+++ F + V+ I PG T + V
Sbjct: 192 RDMKAFGVHVSCIEPGLFKTNLADPV 217
>AF529286-1|AAN04008.1| 319|Homo sapiens microsomal NADP-dependent
retinol dehydrogenase/reductase transcript C protein.
Length = 319
Score = 59.7 bits (138), Expect = 1e-08
Identities = 58/206 (28%), Positives = 90/206 (43%), Gaps = 5/206 (2%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEH 278
+ + +TG SG G A + K+G VI AA T TAL T+ E
Sbjct: 27 ITDKYIFITGCDSGFGNLAARTFDKKGFHVI-------AACLTESGSTALKAETS--ERL 77
Query: 279 SAVELDVSNSKAVQDLVQDTLKQY-KKPPCIIVNSAGI----TRDNWMLKLSEEDYDSVL 443
V LDV++ + V+ Q Q +K ++N+AG+ +W L+ EDY +
Sbjct: 78 RTVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDW---LTLEDYREPI 134
Query: 444 NVNLKGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAA 623
VNL G V + ++ G +IN+SS+ G+ +G Y SK V S
Sbjct: 135 EVNLFGLISVTLNMLPLVKKAQ--GRVINVSSVGGRLAIVG-GGYTPSKYAVEGFNDSLR 191
Query: 624 KELGKFNIRVNAILPGFIDTPIIKTV 701
+++ F + V+ I PG T + V
Sbjct: 192 RDMKAFGVHVSCIEPGLFKTNLADPV 217
>AF343729-1|AAK37528.1| 319|Homo sapiens 3-alpha hydroxysteroid
dehydrogenase protein.
Length = 319
Score = 59.7 bits (138), Expect = 1e-08
Identities = 58/206 (28%), Positives = 90/206 (43%), Gaps = 5/206 (2%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEH 278
+ + +TG SG G A + K+G VI AA T TAL T+ E
Sbjct: 27 ITDKYIFITGCDSGFGNLAARTFDKKGFHVI-------AACLTESGSTALKAETS--ERL 77
Query: 279 SAVELDVSNSKAVQDLVQDTLKQY-KKPPCIIVNSAGI----TRDNWMLKLSEEDYDSVL 443
V LDV++ + V+ Q Q +K ++N+AG+ +W L+ EDY +
Sbjct: 78 RTVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDW---LTLEDYREPI 134
Query: 444 NVNLKGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAA 623
VNL G V + ++ G +IN+SS+ G+ +G Y SK V S
Sbjct: 135 EVNLFGLISVTLNMLPLVKKAQ--GRVINVSSVGGRLAIVG-GGYTPSKYAVEGFNDSLR 191
Query: 624 KELGKFNIRVNAILPGFIDTPIIKTV 701
+++ F + V+ I PG T + V
Sbjct: 192 RDMKAFGVHVSCIEPGLFKTNLADPV 217
>AF295380-1|AAL37037.1| 319|Homo sapiens short-chain
dehydrogenase/reductase RETSDR8 protein.
Length = 319
Score = 59.7 bits (138), Expect = 1e-08
Identities = 58/206 (28%), Positives = 90/206 (43%), Gaps = 5/206 (2%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEH 278
+ + +TG SG G A + K+G VI AA T TAL T+ E
Sbjct: 27 ITDKYIFITGCDSGFGNLAARTFDKKGFHVI-------AACLTESGSTALKAETS--ERL 77
Query: 279 SAVELDVSNSKAVQDLVQDTLKQY-KKPPCIIVNSAGI----TRDNWMLKLSEEDYDSVL 443
V LDV++ + V+ Q Q +K ++N+AG+ +W L+ EDY +
Sbjct: 78 RTVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDW---LTLEDYREPI 134
Query: 444 NVNLKGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAA 623
VNL G V + ++ G +IN+SS+ G+ +G Y SK V S
Sbjct: 135 EVNLFGLISVTLNMLPLVKKAQ--GRVINVSSVGGRLAIVG-GGYTPSKYAVEGFNDSLR 191
Query: 624 KELGKFNIRVNAILPGFIDTPIIKTV 701
+++ F + V+ I PG T + V
Sbjct: 192 RDMKAFGVHVSCIEPGLFKTNLADPV 217
>AC008177-2|AAY24306.1| 245|Homo sapiens unknown protein.
Length = 245
Score = 59.7 bits (138), Expect = 1e-08
Identities = 58/206 (28%), Positives = 90/206 (43%), Gaps = 5/206 (2%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEH 278
+ + +TG SG G A + K+G VI AA T TAL T+ E
Sbjct: 27 ITDKYIFITGCDSGFGNLAARTFDKKGFHVI-------AACLTESGSTALKAETS--ERL 77
Query: 279 SAVELDVSNSKAVQDLVQDTLKQY-KKPPCIIVNSAGI----TRDNWMLKLSEEDYDSVL 443
V LDV++ + V+ Q Q +K ++N+AG+ +W L+ EDY +
Sbjct: 78 RTVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDW---LTLEDYREPI 134
Query: 444 NVNLKGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAA 623
VNL G V + ++ G +IN+SS+ G+ +G Y SK V S
Sbjct: 135 EVNLFGLISVTLNMLPLVKKAQ--GRVINVSSVGGRLAIVG-GGYTPSKYAVEGFNDSLR 191
Query: 624 KELGKFNIRVNAILPGFIDTPIIKTV 701
+++ F + V+ I PG T + V
Sbjct: 192 RDMKAFGVHVSCIEPGLFKTNLADPV 217
>BC095451-1|AAH95451.1| 418|Homo sapiens hydroxysteroid
dehydrogenase like 2 protein.
Length = 418
Score = 58.8 bits (136), Expect = 2e-08
Identities = 50/196 (25%), Positives = 93/196 (47%), Gaps = 3/196 (1%)
Frame = +3
Query: 90 SGLVVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKT-HTALAPGTNG 266
+G + G +TGA GIG+A +K+GA ++ A + + + + T +TA
Sbjct: 5 TGRLAGCTVFITGASRGIGKAIALKAAKDGANIVIAAKTAQPHPKLLGTIYTAAEEIEAV 64
Query: 267 GEEHSAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLN 446
G + +DV + + + V+ +K++ ++ N++ I+ N L + D ++N
Sbjct: 65 GGKALPCIVDVRDEQQISAAVEKAIKKFGGIDILVNNASAISLTN-TLDTPTKRLDLMMN 123
Query: 447 VNLKGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTN--YASSKAGVVAMTQSA 620
VN +GT+L +A + +S V I+NIS + + + Y +K G+
Sbjct: 124 VNTRGTYLASKACIPYLKKSKV-AHILNISPPLNLNPVWFKQHCAYTIAKYGMSMYVLGM 182
Query: 621 AKELGKFNIRVNAILP 668
A+E K I VNA+ P
Sbjct: 183 AEEF-KGEIAVNALWP 197
>AY093428-1|AAM14670.1| 418|Homo sapiens hydroxysteroid
dehydrogenase-like protein protein.
Length = 418
Score = 58.8 bits (136), Expect = 2e-08
Identities = 50/196 (25%), Positives = 93/196 (47%), Gaps = 3/196 (1%)
Frame = +3
Query: 90 SGLVVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKT-HTALAPGTNG 266
+G + G +TGA GIG+A +K+GA ++ A + + + + T +TA
Sbjct: 5 TGRLAGCTVFITGASRGIGKAIALKAAKDGANIVIAAKTAQPHPKLLGTIYTAAEEIEAV 64
Query: 267 GEEHSAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLN 446
G + +DV + + + V+ +K++ ++ N++ I+ N L + D ++N
Sbjct: 65 GGKALPCIVDVRDEQQISAAVEKAIKKFGGIDILVNNASAISLTN-TLDTPTKRLDLMMN 123
Query: 447 VNLKGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTN--YASSKAGVVAMTQSA 620
VN +GT+L +A + +S V I+NIS + + + Y +K G+
Sbjct: 124 VNTRGTYLASKACIPYLKKSKV-AHILNISPPLNLNPVWFKQHCAYTIAKYGMSMYVLGM 182
Query: 621 AKELGKFNIRVNAILP 668
A+E K I VNA+ P
Sbjct: 183 AEEF-KGEIAVNALWP 197
>AL162732-1|CAM17152.1| 418|Homo sapiens hydroxysteroid
dehydrogenase like 2 protein.
Length = 418
Score = 58.8 bits (136), Expect = 2e-08
Identities = 50/196 (25%), Positives = 93/196 (47%), Gaps = 3/196 (1%)
Frame = +3
Query: 90 SGLVVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKT-HTALAPGTNG 266
+G + G +TGA GIG+A +K+GA ++ A + + + + T +TA
Sbjct: 5 TGRLAGCTVFITGASRGIGKAIALKAAKDGANIVIAAKTAQPHPKLLGTIYTAAEEIEAV 64
Query: 267 GEEHSAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLN 446
G + +DV + + + V+ +K++ ++ N++ I+ N L + D ++N
Sbjct: 65 GGKALPCIVDVRDEQQISAAVEKAIKKFGGIDILVNNASAISLTN-TLDTPTKRLDLMMN 123
Query: 447 VNLKGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTN--YASSKAGVVAMTQSA 620
VN +GT+L +A + +S V I+NIS + + + Y +K G+
Sbjct: 124 VNTRGTYLASKACIPYLKKSKV-AHILNISPPLNLNPVWFKQHCAYTIAKYGMSMYVLGM 182
Query: 621 AKELGKFNIRVNAILP 668
A+E K I VNA+ P
Sbjct: 183 AEEF-KGEIAVNALWP 197
>U89717-1|AAB93668.1| 318|Homo sapiens 9-cis-retinol specific
dehydrogenase protein.
Length = 318
Score = 58.4 bits (135), Expect = 3e-08
Identities = 51/192 (26%), Positives = 86/192 (44%), Gaps = 2/192 (1%)
Frame = +3
Query: 120 VTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHSAVELDV 299
+TG SG GR L ++ V+A+ A + G N LD+
Sbjct: 33 ITGCDSGFGRLLALQLDQKSFRVLASCLTPSGAEDL---QGVASSGFN------TTLLDI 83
Query: 300 SNSKAVQDLVQDTLKQYKKPPCI-IVNSAGITRDNWMLK-LSEEDYDSVLNVNLKGTFLV 473
++ ++ Q + K+ +VN+AG+ L+ +D+ VLNVN G V
Sbjct: 84 TDPQSFQQAAKWVEMHVKEAGLFGLVNNAGVAGIIGPTPWLTRDDFQRVLNVNTMGPIGV 143
Query: 474 MQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELGKFNIRV 653
A + ++ G +INI+S++G+ G Y SK G+ A + S +++ F IR
Sbjct: 144 TLALLPLLQQAR--GRVINITSVLGRLAANGG-GYCVSKFGLEAFSDSLRRDVAHFGIRE 200
Query: 654 NAILPGFIDTPI 689
+ + PGF TP+
Sbjct: 201 SIVEPGFFRTPV 212
>BC011968-1|AAH11968.1| 244|Homo sapiens DECR2 protein protein.
Length = 244
Score = 58.4 bits (135), Expect = 3e-08
Identities = 42/132 (31%), Positives = 68/132 (51%), Gaps = 3/132 (2%)
Frame = +3
Query: 285 VELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLK---LSEEDYDSVLNVNL 455
+ +DV AV V LK++ + +I +AG N++ LS + +V++++
Sbjct: 35 LSMDVRAPPAVMAAVDQALKEFGRIDILINCAAG----NFLCPAGALSFNAFKTVMDIDT 90
Query: 456 KGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELG 635
GTF V + + G I+NI++ +G G Q + S+KA V AMT+ A E G
Sbjct: 91 SGTFNVSRVLYEKFFRDH-GGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWG 149
Query: 636 KFNIRVNAILPG 671
NIRVN++ PG
Sbjct: 150 PQNIRVNSLAPG 161
>BC020710-1|AAH20710.1| 317|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 6 homolog (mouse) protein.
Length = 317
Score = 57.6 bits (133), Expect = 4e-08
Identities = 55/222 (24%), Positives = 100/222 (45%), Gaps = 3/222 (1%)
Frame = +3
Query: 27 ILLLRFCEFYTIF*IIQDNMVSGLVVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRK 206
+ L F Y + ++ V + + +TG SG G + L G V+AA
Sbjct: 3 LYLAAFVGLYYLLHWYRERQVVSHLQDKYVFITGCDSGFGNLLARQLDARGLRVLAACLT 62
Query: 207 YEAAVQTIKTHTALAPGTNGGEEHSAVELDVSNSKAVQDLVQDTLKQYKKPPCI--IVNS 380
+ A Q ++ T+ + V LDV+ +++ Q +K++ + +VN+
Sbjct: 63 EKGAEQ-LRGQTS--------DRLETVTLDVTKMESIAAATQ-WVKEHVGDRGLWGLVNN 112
Query: 381 AGITRDNWMLK-LSEEDYDSVLNVNLKGTFLVMQAFAKAMAESSVTGSIINISSIVGKYG 557
AGI + + L+ ED ++L VNL G V + + + G I+N+SSI+G+
Sbjct: 113 AGILTPITLCEWLNTEDSMNMLKVNLIGVIQVTLSMLPLVRRA--RGRIVNVSSILGRVA 170
Query: 558 NMGQTNYASSKAGVVAMTQSAAKELGKFNIRVNAILPGFIDT 683
Y SK GV A + +E+ F ++++ + PG+ T
Sbjct: 171 -FFVGGYCVSKYGVEAFSDILRREIQHFGVKISIVEPGYFRT 211
>AF223225-1|AAF81017.1| 317|Homo sapiens 3-hydroxysteroid epimerase
protein.
Length = 317
Score = 57.6 bits (133), Expect = 4e-08
Identities = 55/222 (24%), Positives = 100/222 (45%), Gaps = 3/222 (1%)
Frame = +3
Query: 27 ILLLRFCEFYTIF*IIQDNMVSGLVVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRK 206
+ L F Y + ++ V + + +TG SG G + L G V+AA
Sbjct: 3 LYLAAFVGLYYLLHWYRERQVVSHLQDKYVFITGCDSGFGNLLARQLDARGLRVLAACLT 62
Query: 207 YEAAVQTIKTHTALAPGTNGGEEHSAVELDVSNSKAVQDLVQDTLKQYKKPPCI--IVNS 380
+ A Q ++ T+ + V LDV+ +++ Q +K++ + +VN+
Sbjct: 63 EKGAEQ-LRGQTS--------DRLETVTLDVTKMESIAAATQ-WVKEHVGDRGLWGLVNN 112
Query: 381 AGITRDNWMLK-LSEEDYDSVLNVNLKGTFLVMQAFAKAMAESSVTGSIINISSIVGKYG 557
AGI + + L+ ED ++L VNL G V + + + G I+N+SSI+G+
Sbjct: 113 AGILTPITLCEWLNTEDSMNMLKVNLIGVIQVTLSMLPLVRRA--RGRIVNVSSILGRVA 170
Query: 558 NMGQTNYASSKAGVVAMTQSAAKELGKFNIRVNAILPGFIDT 683
Y SK GV A + +E+ F ++++ + PG+ T
Sbjct: 171 -FFVGGYCVSKYGVEAFSDILRREIQHFGVKISIVEPGYFRT 211
>AF016509-1|AAB67236.1| 317|Homo sapiens oxidoreductase protein.
Length = 317
Score = 57.6 bits (133), Expect = 4e-08
Identities = 55/222 (24%), Positives = 100/222 (45%), Gaps = 3/222 (1%)
Frame = +3
Query: 27 ILLLRFCEFYTIF*IIQDNMVSGLVVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRK 206
+ L F Y + ++ V + + +TG SG G + L G V+AA
Sbjct: 3 LYLAAFVGLYYLLHWYRERQVVSHLQDKYVFITGCDSGFGNLLARQLDARGLRVLAACLT 62
Query: 207 YEAAVQTIKTHTALAPGTNGGEEHSAVELDVSNSKAVQDLVQDTLKQYKKPPCI--IVNS 380
+ A Q ++ T+ + V LDV+ +++ Q +K++ + +VN+
Sbjct: 63 EKGAEQ-LRGQTS--------DRLETVTLDVTKMESIAAATQ-WVKEHVGDRGLWGLVNN 112
Query: 381 AGITRDNWMLK-LSEEDYDSVLNVNLKGTFLVMQAFAKAMAESSVTGSIINISSIVGKYG 557
AGI + + L+ ED ++L VNL G V + + + G I+N+SSI+G+
Sbjct: 113 AGILTPITLCEWLNTEDSMNMLKVNLIGVIQVTLSMLPLVRRA--RGRIVNVSSILGRVA 170
Query: 558 NMGQTNYASSKAGVVAMTQSAAKELGKFNIRVNAILPGFIDT 683
Y SK GV A + +E+ F ++++ + PG+ T
Sbjct: 171 -FFVGGYCVSKYGVEAFSDILRREIQHFGVKISIVEPGYFRT 211
>BC007337-1|AAH07337.1| 339|Homo sapiens dehydrogenase/reductase
(SDR family) member 7 protein.
Length = 339
Score = 57.2 bits (132), Expect = 6e-08
Identities = 46/193 (23%), Positives = 93/193 (48%), Gaps = 1/193 (0%)
Frame = +3
Query: 120 VTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHSAVELDV 299
VTGA SGIG LSK G +++ + R+ ++ +K L G ++ + LD+
Sbjct: 55 VTGASSGIGEELAYQLSKLGVSLVLSARRVH-ELERVK-RRCLENGNLKEKDILVLPLDL 112
Query: 300 SNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLKGTFLVMQ 479
+++ + + + L+++ + I+VN+ G+++ + + S + Y ++ +N GT + +
Sbjct: 113 TDTGSHEAATKAVLQEFGRID-ILVNNGGMSQRSLCMDTSLDVYRKLIELNYLGTVSLTK 171
Query: 480 AFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELGKF-NIRVN 656
M E G I+ ++SI+G Y +SK + EL + I V+
Sbjct: 172 CVLPHMIERK-QGKIVTVNSILGIISVPLSIGYCASKHALRGFFNGLRTELATYPGIIVS 230
Query: 657 AILPGFIDTPIIK 695
I PG + + I++
Sbjct: 231 NICPGPVQSNIVE 243
>BC000637-1|AAH00637.1| 339|Homo sapiens dehydrogenase/reductase
(SDR family) member 7 protein.
Length = 339
Score = 57.2 bits (132), Expect = 6e-08
Identities = 46/193 (23%), Positives = 93/193 (48%), Gaps = 1/193 (0%)
Frame = +3
Query: 120 VTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHSAVELDV 299
VTGA SGIG LSK G +++ + R+ ++ +K L G ++ + LD+
Sbjct: 55 VTGASSGIGEELAYQLSKLGVSLVLSARRVH-ELERVK-RRCLENGNLKEKDILVLPLDL 112
Query: 300 SNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLKGTFLVMQ 479
+++ + + + L+++ + I+VN+ G+++ + + S + Y ++ +N GT + +
Sbjct: 113 TDTGSHEAATKAVLQEFGRID-ILVNNGGMSQRSLCMDTSLDVYRKLIELNYLGTVSLTK 171
Query: 480 AFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELGKF-NIRVN 656
M E G I+ ++SI+G Y +SK + EL + I V+
Sbjct: 172 CVLPHMIERK-QGKIVTVNSILGIISVPLSIGYCASKHALRGFFNGLRTELATYPGIIVS 230
Query: 657 AILPGFIDTPIIK 695
I PG + + I++
Sbjct: 231 NICPGPVQSNIVE 243
>AY359031-1|AAQ89390.1| 289|Homo sapiens oxidoreductase/S-2 H
protein.
Length = 289
Score = 57.2 bits (132), Expect = 6e-08
Identities = 46/193 (23%), Positives = 93/193 (48%), Gaps = 1/193 (0%)
Frame = +3
Query: 120 VTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHSAVELDV 299
VTGA SGIG LSK G +++ + R+ ++ +K L G ++ + LD+
Sbjct: 5 VTGASSGIGEELAYQLSKLGVSLVLSARRVH-ELERVK-RRCLENGNLKEKDILVLPLDL 62
Query: 300 SNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLKGTFLVMQ 479
+++ + + + L+++ + I+VN+ G+++ + + S + Y ++ +N GT + +
Sbjct: 63 TDTGSHEAATKAVLQEFGRID-ILVNNGGMSQRSLCMDTSLDVYRKLIELNYLGTVSLTK 121
Query: 480 AFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELGKF-NIRVN 656
M E G I+ ++SI+G Y +SK + EL + I V+
Sbjct: 122 CVLPHMIERK-QGKIVTVNSILGIISVPLSIGYCASKHALRGFFNGLRTELATYPGIIVS 180
Query: 657 AILPGFIDTPIIK 695
I PG + + I++
Sbjct: 181 NICPGPVQSNIVE 193
>AF151844-1|AAD34081.1| 339|Homo sapiens CGI-86 protein protein.
Length = 339
Score = 57.2 bits (132), Expect = 6e-08
Identities = 46/193 (23%), Positives = 93/193 (48%), Gaps = 1/193 (0%)
Frame = +3
Query: 120 VTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHSAVELDV 299
VTGA SGIG LSK G +++ + R+ ++ +K L G ++ + LD+
Sbjct: 55 VTGASSGIGEELAYQLSKLGVSLVLSARRVH-ELERVK-RRCLENGNLKEKDILVLPLDL 112
Query: 300 SNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLKGTFLVMQ 479
+++ + + + L+++ + I+VN+ G+++ + + S + Y ++ +N GT + +
Sbjct: 113 TDTGSHEAATKAVLQEFGRID-ILVNNGGMSQRSLCMDTSLDVYRKLIELNYLGTVSLTK 171
Query: 480 AFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELGKF-NIRVN 656
M E G I+ ++SI+G Y +SK + EL + I V+
Sbjct: 172 CVLPHMIERK-QGKIVTVNSILGIISVPLSIGYCASKHALRGFFNGLRTELATYPGIIVS 230
Query: 657 AILPGFIDTPIIK 695
I PG + + I++
Sbjct: 231 NICPGPVQSNIVE 243
>AF126782-1|AAF06941.1| 289|Homo sapiens retinal short-chain
dehydrogenase/reductase retSDR4 protein.
Length = 289
Score = 57.2 bits (132), Expect = 6e-08
Identities = 46/193 (23%), Positives = 93/193 (48%), Gaps = 1/193 (0%)
Frame = +3
Query: 120 VTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHSAVELDV 299
VTGA SGIG LSK G +++ + R+ ++ +K L G ++ + LD+
Sbjct: 5 VTGASSGIGEELAYQLSKLGVSLVLSARRVH-ELERVK-RRCLENGNLKEKDILVLPLDL 62
Query: 300 SNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLKGTFLVMQ 479
+++ + + + L+++ + I+VN+ G+++ + + S + Y ++ +N GT + +
Sbjct: 63 TDTGSHEAATKAVLQEFGRID-ILVNNGGMSQRSLCMDTSLDVYRKLIELNYLGTVSLTK 121
Query: 480 AFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELGKF-NIRVN 656
M E G I+ ++SI+G Y +SK + EL + I V+
Sbjct: 122 CVLPHMIERK-QGKIVTVNSILGIISVPLSIGYCASKHALRGFFNGLRTELATYPGIIVS 180
Query: 657 AILPGFIDTPIIK 695
I PG + + I++
Sbjct: 181 NICPGPVQSNIVE 193
>AK058159-1|BAB71694.1| 313|Homo sapiens protein ( Homo sapiens
cDNA FLJ25430 fis, clone TST06262. ).
Length = 313
Score = 56.4 bits (130), Expect = 1e-07
Identities = 54/204 (26%), Positives = 87/204 (42%), Gaps = 7/204 (3%)
Frame = +3
Query: 105 GRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHSA 284
G++ +VTGA GIGR L K GATV R + T++ A G +
Sbjct: 7 GQVCVVTGASRGIGRGIALQLCKAGATVYITGRH----LDTLRVVAQEAQSLGG--QCVP 60
Query: 285 VELDVSNSKAVQDLVQDTLKQYKKPPCIIVNS--AGI-----TRDNWMLKLSEEDYDSVL 443
V D S V+ L + ++ + ++VN+ AG+ TR+ + +D +
Sbjct: 61 VVCDSSQESEVRSLFEQVDREQQGRLDVLVNNAYAGVQTILNTRNKAFWETPASMWDDIN 120
Query: 444 NVNLKGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAA 623
NV L+G + A+ M + G I+ ISS G M Y KA + A
Sbjct: 121 NVGLRGHYFCSVYGARLMVPAG-QGLIVVISS-PGSLQYMFNVPYGVGKAACDKLAADCA 178
Query: 624 KELGKFNIRVNAILPGFIDTPIIK 695
EL + + ++ PG + T ++K
Sbjct: 179 HELRRHGVSCVSLWPGIVQTELLK 202
>AF418205-1|AAN32660.1| 313|Homo sapiens dehydrogenase/reductase
SDR family member 1 protein.
Length = 313
Score = 56.4 bits (130), Expect = 1e-07
Identities = 54/204 (26%), Positives = 87/204 (42%), Gaps = 7/204 (3%)
Frame = +3
Query: 105 GRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHSA 284
G++ +VTGA GIGR L K GATV R + T++ A G +
Sbjct: 7 GQVCVVTGASRGIGRGIALQLCKAGATVYITGRH----LDTLRVVAQEAQSLGG--QCVP 60
Query: 285 VELDVSNSKAVQDLVQDTLKQYKKPPCIIVNS--AGI-----TRDNWMLKLSEEDYDSVL 443
V D S V+ L + ++ + ++VN+ AG+ TR+ + +D +
Sbjct: 61 VVCDSSQESEVRSLFEQVDREQQGRLDVLVNNAYAGVQTILNTRNKAFWETPASMWDDIN 120
Query: 444 NVNLKGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAA 623
NV L+G + A+ M + G I+ ISS G M Y KA + A
Sbjct: 121 NVGLRGHYFCSVYGARLMVPAG-QGLIVVISS-PGSLQYMFNVPYGVGKAACDKLAADCA 178
Query: 624 KELGKFNIRVNAILPGFIDTPIIK 695
EL + + ++ PG + T ++K
Sbjct: 179 HELRRHGVSCVSLWPGIVQTELLK 202
>BC014057-1|AAH14057.1| 313|Homo sapiens DHRS1 protein protein.
Length = 313
Score = 56.0 bits (129), Expect = 1e-07
Identities = 54/204 (26%), Positives = 87/204 (42%), Gaps = 7/204 (3%)
Frame = +3
Query: 105 GRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHSA 284
G++ +VTGA GIGR L K GATV R + T++ A G +
Sbjct: 7 GQVCVVTGASRGIGRGIALQLCKAGATVYITGRH----LDTLRVVAQEAQSLGG--QCVP 60
Query: 285 VELDVSNSKAVQDLVQDTLKQYKKPPCIIVNS--AGI-----TRDNWMLKLSEEDYDSVL 443
V D S V+ L + ++ + ++VN+ AG+ TR+ + +D +
Sbjct: 61 VVCDSSQESEVRSLFEQVDREQQGRLDVLVNNAYAGVQTILNTRNKAFWETPASMWDDIN 120
Query: 444 NVNLKGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAA 623
NV L+G + A+ M + G I+ ISS G M Y KA + A
Sbjct: 121 NVGLRGHYFCSVYGARLMVPAG-QGLIVVISS-PGSLQYMFNVLYGVGKAACDKLAADCA 178
Query: 624 KELGKFNIRVNAILPGFIDTPIIK 695
EL + + ++ PG + T ++K
Sbjct: 179 HELRRHGVSCVSLWPGIVQTELLK 202
>BC104218-1|AAI04219.1| 330|Homo sapiens hydroxysteroid
dehydrogenase like 1 protein.
Length = 330
Score = 55.6 bits (128), Expect = 2e-07
Identities = 49/195 (25%), Positives = 89/195 (45%), Gaps = 2/195 (1%)
Frame = +3
Query: 105 GRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHSA 284
GR A+V+GA GIG+A + L+ G +I R E +Q + A E
Sbjct: 67 GRWAVVSGATDGIGKAYAEELASRGLNIILISRN-EEKLQVVAKDIA----DTYKVETDI 121
Query: 285 VELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGI--TRDNWMLKLSEEDYDSVLNVNLK 458
+ D S+ + + +++ LK K I+VN+ G+ + +LSE+ ++NVN+
Sbjct: 122 IVADFSSGREIYLPIREALKD--KDVGILVNNVGVFYPYPQYFTQLSEDKLWDIINVNIA 179
Query: 459 GTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELGK 638
L++ M E G+I+ ISS +++SKA + +++ E
Sbjct: 180 AASLMVHVVLPGMVERK-KGAIVTISSGSCCKPTPQLAAFSASKAYLDHFSRALQYEYAS 238
Query: 639 FNIRVNAILPGFIDT 683
I V +++P ++ T
Sbjct: 239 KGIFVQSLIPFYVAT 253
>BC015943-1|AAH15943.1| 313|Homo sapiens DHRS1 protein protein.
Length = 313
Score = 55.6 bits (128), Expect = 2e-07
Identities = 54/204 (26%), Positives = 86/204 (42%), Gaps = 7/204 (3%)
Frame = +3
Query: 105 GRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHSA 284
G+ +VTGA GIGR L K GATV R + T++ A G +
Sbjct: 7 GQACVVTGASRGIGRGIALQLCKAGATVYITGRH----LDTLRVVAQEAQSLGG--QCVP 60
Query: 285 VELDVSNSKAVQDLVQDTLKQYKKPPCIIVNS--AGI-----TRDNWMLKLSEEDYDSVL 443
V D S V+ L + ++ + ++VN+ AG+ TR+ + +D +
Sbjct: 61 VVCDSSQESEVRSLFEQVDREQQGRLDVLVNNAYAGVQTILNTRNKAFWETPASMWDDIN 120
Query: 444 NVNLKGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAA 623
NV L+G + A+ M + G I+ ISS G M Y KA + A
Sbjct: 121 NVGLRGHYFCSVYGARLMVPAG-QGLIVVISS-PGSLQYMFNVPYGVGKAACDKLAADCA 178
Query: 624 KELGKFNIRVNAILPGFIDTPIIK 695
EL + + ++ PG + T ++K
Sbjct: 179 HELRRHGVSCVSLWPGIVQTELLK 202
>AY028377-1|AAK16927.1| 309|Homo sapiens steroid dehydrogenase-like
protein protein.
Length = 309
Score = 55.6 bits (128), Expect = 2e-07
Identities = 49/195 (25%), Positives = 89/195 (45%), Gaps = 2/195 (1%)
Frame = +3
Query: 105 GRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHSA 284
GR A+V+GA GIG+A + L+ G +I R E +Q + A E
Sbjct: 46 GRWAVVSGATDGIGKAYAEELASRGLNIILISRN-EEKLQVVAKDIA----DTYKVETDI 100
Query: 285 VELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGI--TRDNWMLKLSEEDYDSVLNVNLK 458
+ D S+ + + +++ LK K I+VN+ G+ + +LSE+ ++NVN+
Sbjct: 101 IVADFSSGREIYLPIREALKD--KDVGILVNNVGVFYPYPQYFTQLSEDKLWDIINVNIA 158
Query: 459 GTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELGK 638
L++ M E G+I+ ISS +++SKA + +++ E
Sbjct: 159 AASLMVHVVLPGMVERK-KGAIVTISSGSCCKPTPQLAAFSASKAYLDHFSRALQYEYAS 217
Query: 639 FNIRVNAILPGFIDT 683
I V +++P ++ T
Sbjct: 218 KGIFVQSLIPFYVAT 232
>AK074878-1|BAC11262.1| 330|Homo sapiens protein ( Homo sapiens
cDNA FLJ90397 fis, clone NT2RP2005878, moderately
similar to PUTATIVE STEROID DEHYDROGENASE KIK-I (EC
1.1.1.-). ).
Length = 330
Score = 55.6 bits (128), Expect = 2e-07
Identities = 49/195 (25%), Positives = 89/195 (45%), Gaps = 2/195 (1%)
Frame = +3
Query: 105 GRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHSA 284
GR A+V+GA GIG+A + L+ G +I R E +Q + A E
Sbjct: 67 GRWAVVSGATDGIGKAYAEELASRGLNIILISRN-EEKLQVVAKDIA----DTYKVETDI 121
Query: 285 VELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGI--TRDNWMLKLSEEDYDSVLNVNLK 458
+ D S+ + + +++ LK K I+VN+ G+ + +LSE+ ++NVN+
Sbjct: 122 IVADFSSGREIYLPIREALKD--KDVGILVNNVGVFYPYPQYFTQLSEDKLWDIINVNIA 179
Query: 459 GTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELGK 638
L++ M E G+I+ ISS +++SKA + +++ E
Sbjct: 180 AASLMVHVVLPGMVERK-KGAIVTISSGSCCKPTPQLAAFSASKAYLDHFSRALQYEYAS 238
Query: 639 FNIRVNAILPGFIDT 683
I V +++P ++ T
Sbjct: 239 KGIFVQSLIPFYVAT 253
>AF237684-1|AAK15047.1| 309|Homo sapiens steroid dehydrogenase-like
protein protein.
Length = 309
Score = 55.6 bits (128), Expect = 2e-07
Identities = 49/195 (25%), Positives = 89/195 (45%), Gaps = 2/195 (1%)
Frame = +3
Query: 105 GRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHSA 284
GR A+V+GA GIG+A + L+ G +I R E +Q + A E
Sbjct: 46 GRWAVVSGATDGIGKAYAEELASRGLNIILISRN-EEKLQVVAKDIA----DTYKVETDI 100
Query: 285 VELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGI--TRDNWMLKLSEEDYDSVLNVNLK 458
+ D S+ + + +++ LK K I+VN+ G+ + +LSE+ ++NVN+
Sbjct: 101 IVADFSSGREIYLPIREALKD--KDVGILVNNVGVFYPYPQYFTQLSEDKLWDIINVNIA 158
Query: 459 GTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELGK 638
L++ M E G+I+ ISS +++SKA + +++ E
Sbjct: 159 AASLMVHVVLPGMVERK-KGAIVTISSGSCCKPTPQLAAFSASKAYLDHFSRALQYEYAS 217
Query: 639 FNIRVNAILPGFIDT 683
I V +++P ++ T
Sbjct: 218 KGIFVQSLIPFYVAT 232
>BC101553-1|AAI01554.1| 313|Homo sapiens orphan short-chain
dehydrogenase / reductase protein.
Length = 313
Score = 55.2 bits (127), Expect = 2e-07
Identities = 58/206 (28%), Positives = 95/206 (46%), Gaps = 2/206 (0%)
Frame = +3
Query: 81 NMVSGLVVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGT 260
N+V L + +TG SG G + L G V+AA E + Q ++ T+ T
Sbjct: 18 NLVGNLSE-KYVFITGCDSGFGNLLAKQLVDRGMQVLAACFTEEGS-QKLQRDTSYRLQT 75
Query: 261 NGGEEHSAVELDVSNSKAVQDLVQDTL-KQYKKPPCIIVNSAGITRDNWMLK-LSEEDYD 434
LDV+ S++++ Q K ++ +VN+AG+ + + L+++D+
Sbjct: 76 --------TLLDVTKSESIKAAAQWVRDKVGEQGLWALVNNAGVGLPSGPNEWLTKDDFV 127
Query: 435 SVLNVNLKGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQ 614
V+NVNL G L+ G ++N+SS G+ +G Y SK GV A +
Sbjct: 128 KVINVNLVG--LIEVTLHMLPMVKRARGRVVNMSSSGGRVAVIG-GGYCVSKFGVEAFSD 184
Query: 615 SAAKELGKFNIRVNAILPGFIDTPII 692
S +EL F ++V I PG T I+
Sbjct: 185 SIRRELYYFGVKVCIIEPGNYRTAIL 210
>BC101551-1|AAI01552.1| 313|Homo sapiens orphan short-chain
dehydrogenase / reductase protein.
Length = 313
Score = 55.2 bits (127), Expect = 2e-07
Identities = 58/206 (28%), Positives = 95/206 (46%), Gaps = 2/206 (0%)
Frame = +3
Query: 81 NMVSGLVVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGT 260
N+V L + +TG SG G + L G V+AA E + Q ++ T+ T
Sbjct: 18 NLVGNLSE-KYVFITGCDSGFGNLLAKQLVDRGMQVLAACFTEEGS-QKLQRDTSYRLQT 75
Query: 261 NGGEEHSAVELDVSNSKAVQDLVQDTL-KQYKKPPCIIVNSAGITRDNWMLK-LSEEDYD 434
LDV+ S++++ Q K ++ +VN+AG+ + + L+++D+
Sbjct: 76 --------TLLDVTKSESIKAAAQWVRDKVGEQGLWALVNNAGVGLPSGPNEWLTKDDFV 127
Query: 435 SVLNVNLKGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQ 614
V+NVNL G L+ G ++N+SS G+ +G Y SK GV A +
Sbjct: 128 KVINVNLVG--LIEVTLHMLPMVKRARGRVVNMSSSGGRVAVIG-GGYCVSKFGVEAFSD 184
Query: 615 SAAKELGKFNIRVNAILPGFIDTPII 692
S +EL F ++V I PG T I+
Sbjct: 185 SIRRELYYFGVKVCIIEPGNYRTAIL 210
>BC025724-1|AAH25724.1| 316|Homo sapiens retinol dehydrogenase 12
(all-trans/9-cis/11-cis) protein.
Length = 316
Score = 55.2 bits (127), Expect = 2e-07
Identities = 51/212 (24%), Positives = 100/212 (47%), Gaps = 15/212 (7%)
Frame = +3
Query: 105 GRLALVTGAGSGIGRAACQVLSKEGATVIAADR---KYEAAVQTIKTHTALAPGTNGGEE 275
G++ ++TGA +GIG+ + L+ GA V A R K E+A I+ T +
Sbjct: 39 GKVVVITGANTGIGKETARELASRGARVYIACRDVLKGESAASEIRVDTK-------NSQ 91
Query: 276 HSAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNL 455
+LD+S++K+++ + L + +K I++N+AG+ + + + +++ L VN
Sbjct: 92 VLVRKLDLSDTKSIRAFAEGFLAE-EKQLHILINNAGVMMCPY--SKTADGFETHLGVNH 148
Query: 456 KGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMG----QTN--------YASSKAGV 599
G FL+ + + + S ++N+SS+ G + Q+ Y SK
Sbjct: 149 LGHFLLTYLLLEQL-KVSAPARVVNVSSVAHHIGKIPFHDLQSEKRYSRGFAYCHSKLAN 207
Query: 600 VAMTQSAAKELGKFNIRVNAILPGFIDTPIIK 695
V T+ AK L + A+ PG + + +++
Sbjct: 208 VLFTRELAKRLQGTGVTTYAVHPGVVRSELVR 239
>AY044434-1|AAK95856.1| 313|Homo sapiens retinol dehydrogenase
similar protein protein.
Length = 313
Score = 55.2 bits (127), Expect = 2e-07
Identities = 58/206 (28%), Positives = 95/206 (46%), Gaps = 2/206 (0%)
Frame = +3
Query: 81 NMVSGLVVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGT 260
N+V L + +TG SG G + L G V+AA E + Q ++ T+ T
Sbjct: 18 NLVGNLSE-KYVFITGCDSGFGNLLAKQLVDRGMQVLAACFTEEGS-QKLQRDTSYRLQT 75
Query: 261 NGGEEHSAVELDVSNSKAVQDLVQDTL-KQYKKPPCIIVNSAGITRDNWMLK-LSEEDYD 434
LDV+ S++++ Q K ++ +VN+AG+ + + L+++D+
Sbjct: 76 --------TLLDVTKSESIKAAAQWVRDKVGEQGLWALVNNAGVGLPSGPNEWLTKDDFV 127
Query: 435 SVLNVNLKGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQ 614
V+NVNL G L+ G ++N+SS G+ +G Y SK GV A +
Sbjct: 128 KVINVNLVG--LIEVTLHMLPMVKRARGRVVNMSSSGGRVAVIG-GGYCVSKFGVEAFSD 184
Query: 615 SAAKELGKFNIRVNAILPGFIDTPII 692
S +EL F ++V I PG T I+
Sbjct: 185 SIRRELYYFGVKVCIIEPGNYRTAIL 210
>AK054835-1|BAB70811.1| 316|Homo sapiens (ARSDR1) mRNA. protein.
Length = 316
Score = 55.2 bits (127), Expect = 2e-07
Identities = 51/212 (24%), Positives = 100/212 (47%), Gaps = 15/212 (7%)
Frame = +3
Query: 105 GRLALVTGAGSGIGRAACQVLSKEGATVIAADR---KYEAAVQTIKTHTALAPGTNGGEE 275
G++ ++TGA +GIG+ + L+ GA V A R K E+A I+ T +
Sbjct: 39 GKVVVITGANTGIGKETARELASRGARVYIACRDVLKGESAASEIRVDTK-------NSQ 91
Query: 276 HSAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNL 455
+LD+S++K+++ + L + +K I++N+AG+ + + + +++ L VN
Sbjct: 92 VLVRKLDLSDTKSIRAFAEGFLAE-EKQLHILINNAGVMMCPY--SKTADGFETHLGVNH 148
Query: 456 KGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMG----QTN--------YASSKAGV 599
G FL+ + + + S ++N+SS+ G + Q+ Y SK
Sbjct: 149 LGHFLLTYLLLERL-KVSAPARVVNVSSVAHHIGKIPFHDLQSEKRYSRGFAYCHSKLAN 207
Query: 600 VAMTQSAAKELGKFNIRVNAILPGFIDTPIIK 695
V T+ AK L + A+ PG + + +++
Sbjct: 208 VLFTRELAKRLQGTGVTTYAVHPGVVRSELVR 239
>BC106917-1|AAI06918.1| 330|Homo sapiens hydroxysteroid
dehydrogenase like 1 protein.
Length = 330
Score = 54.4 bits (125), Expect = 4e-07
Identities = 48/195 (24%), Positives = 89/195 (45%), Gaps = 2/195 (1%)
Frame = +3
Query: 105 GRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHSA 284
GR A+V+GA GIG+A + L+ G +I R E +Q + A E
Sbjct: 67 GRWAVVSGATDGIGKAYAEELASRGLNIILISRN-EEKLQVVAKDIA----DTYKVETDI 121
Query: 285 VELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGI--TRDNWMLKLSEEDYDSVLNVNLK 458
+ D S+ + + +++ LK K I+VN+ G+ + +LSE+ ++NVN+
Sbjct: 122 IVADFSSGREIYLPIREALKD--KDVGILVNNVGVFYPYPQYFTQLSEDKLWDIINVNIA 179
Query: 459 GTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELGK 638
L++ M E G+I+ ISS +++S+A + +++ E
Sbjct: 180 AASLMVHVVLPGMVERK-KGAIVTISSGSCCKPTPQLAAFSASRAYLDHFSRALQYEYAS 238
Query: 639 FNIRVNAILPGFIDT 683
I V +++P ++ T
Sbjct: 239 KGIFVQSLIPFYVAT 253
>BC104219-1|AAI04220.1| 330|Homo sapiens hydroxysteroid
dehydrogenase like 1 protein.
Length = 330
Score = 54.4 bits (125), Expect = 4e-07
Identities = 48/195 (24%), Positives = 89/195 (45%), Gaps = 2/195 (1%)
Frame = +3
Query: 105 GRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHSA 284
GR A+V+GA GIG+A + L+ G +I R E +Q + A E
Sbjct: 67 GRWAVVSGATDGIGKAYAEELASRGLNIILISRN-EEKLQVVAKDIA----DTYKVETDI 121
Query: 285 VELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGI--TRDNWMLKLSEEDYDSVLNVNLK 458
+ D S+ + + +++ LK K I+VN+ G+ + +LSE+ ++NVN+
Sbjct: 122 IVADFSSGREIYLPIREALKD--KDVGILVNNVGVFYPYPQYFTQLSEDKLWDIINVNIA 179
Query: 459 GTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELGK 638
L++ M E G+I+ ISS +++S+A + +++ E
Sbjct: 180 AASLMVHVVLPGMVERK-KGAIVTISSGSCCKPTPQLAAFSASRAYLDHFSRALQYEYAS 238
Query: 639 FNIRVNAILPGFIDT 683
I V +++P ++ T
Sbjct: 239 KGIFVQSLIPFYVAT 253
>BC018084-1|AAH18084.2| 330|Homo sapiens hydroxysteroid
dehydrogenase like 1 protein.
Length = 330
Score = 54.4 bits (125), Expect = 4e-07
Identities = 48/193 (24%), Positives = 88/193 (45%), Gaps = 2/193 (1%)
Frame = +3
Query: 105 GRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHSA 284
GR A+V+GA GIG+A + L+ G +I R E +Q + A E
Sbjct: 67 GRWAVVSGATDGIGKAYAEELASRGLNIILISRN-EEKLQVVAKDIA----DTYKVETDI 121
Query: 285 VELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGI--TRDNWMLKLSEEDYDSVLNVNLK 458
+ D S+ + + +++ LK K I+VN+ G+ + +LSE+ ++NVN+
Sbjct: 122 IVADFSSGREIYLPIREALKD--KDVGILVNNVGVFYPYPQYFTQLSEDKLWDIINVNIA 179
Query: 459 GTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELGK 638
L++ M E G+I+ ISS +++SKA + +++ E
Sbjct: 180 AASLMVHVVLPGMVERK-KGAIVTISSGSCCKPTPQLAAFSASKAYLDHFSRALQYEYAS 238
Query: 639 FNIRVNAILPGFI 677
I V +++P ++
Sbjct: 239 KGIFVQSLIPFYV 251
>AF069291-3|AAC62233.1| 188|Homo sapiens 2,4-dienoyl-CoA reductase
protein.
Length = 188
Score = 54.0 bits (124), Expect = 5e-07
Identities = 36/134 (26%), Positives = 65/134 (48%)
Frame = +3
Query: 105 GRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHSA 284
G++A +TG G+G+G+ +LS GA + A RK + +K G + H A
Sbjct: 59 GKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRK----MDVLKATAEQISSQTGNKVH-A 113
Query: 285 VELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLKGT 464
++ DV + VQ+ V + +K P +I N+AG + +LS + ++ ++ L GT
Sbjct: 114 IQCDVRDPDMVQNTVSELIKVAGHPNIVINNAAG-NFISPTERLSPNAWKTITDIVLNGT 172
Query: 465 FLVMQAFAKAMAES 506
V K + ++
Sbjct: 173 AFVTLEIGKQLIKA 186
>U63296-1|AAB53034.1| 143|Homo sapiens 15-hydroxyprostaglandin
dehydrogenase protein.
Length = 143
Score = 53.6 bits (123), Expect = 7e-07
Identities = 45/156 (28%), Positives = 77/156 (49%), Gaps = 4/156 (2%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEH 278
V G++ALVTGA GIGRA + L +GA V D EA VQ A ++
Sbjct: 3 VNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQC----KAALDEQFEPQKT 58
Query: 279 SAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNL- 455
++ DV++ + ++D + + + + I+VN+AG+ +E++++ L +NL
Sbjct: 59 LFIQCDVADQQQLRDTFRKVVDHFGRLD-ILVNNAGVN--------NEKNWEKTLQINLV 109
Query: 456 ---KGTFLVMQAFAKAMAESSVTGSIINISSIVGKY 554
GT+L + +K G IIN+SS+ +
Sbjct: 110 SVISGTYLGLDYMSK--QNGGEGGIIINMSSLAAHH 143
>AF240698-1|AAF82748.1| 279|Homo sapiens retinol dehydrogenase
homolog isoform-1 protein.
Length = 279
Score = 53.6 bits (123), Expect = 7e-07
Identities = 54/193 (27%), Positives = 85/193 (44%), Gaps = 5/193 (2%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEH 278
+ + +TG SG G A + K+G VI AA T TAL T+ E
Sbjct: 27 ITDKYIFITGCDSGFGNLAARTFDKKGFHVI-------AACLTESGSTALKAETS--ERL 77
Query: 279 SAVELDVSNSKAVQDLVQDTLKQY-KKPPCIIVNSAGI----TRDNWMLKLSEEDYDSVL 443
V LDV++ + V+ Q Q +K ++N+AG+ +W L+ EDY +
Sbjct: 78 RTVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDW---LTLEDYREPI 134
Query: 444 NVNLKGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAA 623
VNL G V + ++ G +IN+SS+ G+ +G Y SK V S
Sbjct: 135 EVNLFGLISVTLNMLPLVKKAQ--GRVINVSSVGGRLAIVG-GGYTPSKYAVEGFNDSLR 191
Query: 624 KELGKFNIRVNAI 662
+++ F + V+ I
Sbjct: 192 RDMKAFGVHVSCI 204
>AY186250-1|AAO72314.1| 264|Homo sapiens 17-beta hydroxysteroid
dehydrogenase isoform 1 protein.
Length = 264
Score = 52.8 bits (121), Expect = 1e-06
Identities = 37/126 (29%), Positives = 58/126 (46%), Gaps = 6/126 (4%)
Frame = +3
Query: 366 IIVNSAGITRDNWMLKLSEEDYDSVLNVNLKGTFLVMQAFAKAMAESSVTGSIINISSIV 545
I+VN+AG +L +E+ VN+ G F + +A +M E + G I+ ++S+
Sbjct: 80 IVVNNAGTVYPADLLSTKDEEITKTFEVNILGHFWITKALLPSMMERN-HGHIVTVASVC 138
Query: 546 GKYGNMGQTNYASSKAGVVAMTQSAAKE---LGKFNIRVNAILPGFIDTPIIKTVPDK-- 710
G G Y SSK V + E LGK I+ + + P F++T K +
Sbjct: 139 GHEGIPYLIPYCSSKFAAVGFHRGLTSELQALGKTGIKTSCLCPVFVNTGFTKNPSTRLW 198
Query: 711 -VKETD 725
V ETD
Sbjct: 199 PVLETD 204
Score = 30.3 bits (65), Expect = 7.6
Identities = 13/34 (38%), Positives = 19/34 (55%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAAD 200
V G + L+TGAG GIGR +K + ++ D
Sbjct: 34 VAGEIVLITGAGHGIGRQTTYEFAKRQSILVLWD 67
>U05659-1|AAC50066.1| 310|Homo sapiens 17beta-hydroxysteroid
dehydrogenase type 3 protein.
Length = 310
Score = 52.4 bits (120), Expect = 2e-06
Identities = 50/201 (24%), Positives = 94/201 (46%), Gaps = 3/201 (1%)
Frame = +3
Query: 102 VGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHS 281
+G+ A++TGAG GIG+A L+K G V+ R E ++ I T G
Sbjct: 47 MGQWAVITGAGDGIGKAYSFELAKRGLNVVLISRTLE-KLEAIATEIE----RTTGRSVK 101
Query: 282 AVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRD---NWMLKLSEEDYDSVLNVN 452
++ D + + + +++ L + I+VN+ G+ + + L +E S+++ N
Sbjct: 102 IIQADFTKDD-IYEHIKEKLAGLEIG--ILVNNVGMLPNLLPSHFLNAPDE-IQSLIHCN 157
Query: 453 LKGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKEL 632
+ + Q K M ES G I+NISS + + + Y++SKA V A +++ +E
Sbjct: 158 ITSVVKMTQLILKHM-ESRQKGLILNISSGIALFPWPLYSMYSASKAFVCAFSKALQEEY 216
Query: 633 GKFNIRVNAILPGFIDTPIIK 695
+ + + P + T + K
Sbjct: 217 KAKEVIIQVLTPYAVSTAMTK 237
>CR541894-1|CAG46692.1| 310|Homo sapiens HSD17B3 protein.
Length = 310
Score = 52.4 bits (120), Expect = 2e-06
Identities = 50/201 (24%), Positives = 94/201 (46%), Gaps = 3/201 (1%)
Frame = +3
Query: 102 VGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHS 281
+G+ A++TGAG GIG+A L+K G V+ R E ++ I T G
Sbjct: 47 MGQWAVITGAGDGIGKAYSFELAKRGLNVVLISRTLE-KLEAIATEIE----RTTGRSVK 101
Query: 282 AVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRD---NWMLKLSEEDYDSVLNVN 452
++ D + + + +++ L + I+VN+ G+ + + L +E S+++ N
Sbjct: 102 IIQADFTKDD-IYEHIKEKLAGLEIG--ILVNNVGMLPNLLPSHFLNAPDE-IQSLIHCN 157
Query: 453 LKGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKEL 632
+ + Q K M ES G I+NISS + + + Y++SKA V A +++ +E
Sbjct: 158 ITSVVKMTQLILKHM-ESRQKGLILNISSGIALFPWPLYSMYSASKAFVCAFSKALQEEY 216
Query: 633 GKFNIRVNAILPGFIDTPIIK 695
+ + + P + T + K
Sbjct: 217 KAKEVIIQVLTPYAVSTAMTK 237
>CR457356-1|CAG33637.1| 181|Homo sapiens MGC4172 protein.
Length = 181
Score = 52.4 bits (120), Expect = 2e-06
Identities = 37/123 (30%), Positives = 66/123 (53%), Gaps = 5/123 (4%)
Frame = +3
Query: 366 IIVNSAGITRDNWMLKLSEEDYDSVLNVNLKGTFLVMQAFAKAMAESSV-TGSIINISSI 542
I +N+AG+ R + +L S + + NVN+ + + ++M E +V G IINI+S+
Sbjct: 14 ICINNAGLARPDTLLSGSTSGWKDMFNVNVLALSICTREAYQSMKERNVDDGHIININSM 73
Query: 543 VG-KYGNMGQTN-YASSKAGVVAMTQSAAKEL--GKFNIRVNAILPGFIDTPIIKTVPDK 710
G + + T+ Y+++K V A+T+ +EL + +IR I PG ++T + DK
Sbjct: 74 SGHRVLPLSVTHFYSATKYAVTALTEGLRQELREAQTHIRATCISPGVVETQFAFKLHDK 133
Query: 711 VKE 719
E
Sbjct: 134 DPE 136
>BC034281-1|AAH34281.1| 310|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 3 protein.
Length = 310
Score = 52.4 bits (120), Expect = 2e-06
Identities = 50/201 (24%), Positives = 94/201 (46%), Gaps = 3/201 (1%)
Frame = +3
Query: 102 VGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHS 281
+G+ A++TGAG GIG+A L+K G V+ R E ++ I T G
Sbjct: 47 MGQWAVITGAGDGIGKAYSFELAKRGLNVVLISRTLE-KLEAIATEIE----RTTGRSVK 101
Query: 282 AVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRD---NWMLKLSEEDYDSVLNVN 452
++ D + + + +++ L + I+VN+ G+ + + L +E S+++ N
Sbjct: 102 IIQADFTKDD-IYEHIKEKLAGLEIG--ILVNNVGMLPNLLPSHFLNAPDE-IQSLIHCN 157
Query: 453 LKGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKEL 632
+ + Q K M ES G I+NISS + + + Y++SKA V A +++ +E
Sbjct: 158 ITSVVKMTQLILKHM-ESRQKGLILNISSGIALFPWPLYSMYSASKAFVCAFSKALQEEY 216
Query: 633 GKFNIRVNAILPGFIDTPIIK 695
+ + + P + T + K
Sbjct: 217 KAKEVIIQVLTPYAVSTAMTK 237
>AY341031-1|AAP88937.1| 310|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 3 protein.
Length = 310
Score = 52.4 bits (120), Expect = 2e-06
Identities = 50/201 (24%), Positives = 94/201 (46%), Gaps = 3/201 (1%)
Frame = +3
Query: 102 VGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHS 281
+G+ A++TGAG GIG+A L+K G V+ R E ++ I T G
Sbjct: 47 MGQWAVITGAGDGIGKAYSFELAKRGLNVVLISRTLE-KLEAIATEIE----RTTGRSVK 101
Query: 282 AVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRD---NWMLKLSEEDYDSVLNVN 452
++ D + + + +++ L + I+VN+ G+ + + L +E S+++ N
Sbjct: 102 IIQADFTKDD-IYEHIKEKLAGLEIG--ILVNNVGMLPNLLPSHFLNAPDE-IQSLIHCN 157
Query: 453 LKGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKEL 632
+ + Q K M ES G I+NISS + + + Y++SKA V A +++ +E
Sbjct: 158 ITSVVKMTQLILKHM-ESRQKGLILNISSGIALFPWPLYSMYSASKAFVCAFSKALQEEY 216
Query: 633 GKFNIRVNAILPGFIDTPIIK 695
+ + + P + T + K
Sbjct: 217 KAKEVIIQVLTPYAVSTAMTK 237
>AL160269-3|CAH71615.1| 310|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 3 protein.
Length = 310
Score = 52.4 bits (120), Expect = 2e-06
Identities = 50/201 (24%), Positives = 94/201 (46%), Gaps = 3/201 (1%)
Frame = +3
Query: 102 VGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHS 281
+G+ A++TGAG GIG+A L+K G V+ R E ++ I T G
Sbjct: 47 MGQWAVITGAGDGIGKAYSFELAKRGLNVVLISRTLE-KLEAIATEIE----RTTGRSVK 101
Query: 282 AVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRD---NWMLKLSEEDYDSVLNVN 452
++ D + + + +++ L + I+VN+ G+ + + L +E S+++ N
Sbjct: 102 IIQADFTKDD-IYEHIKEKLAGLEIG--ILVNNVGMLPNLLPSHFLNAPDE-IQSLIHCN 157
Query: 453 LKGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKEL 632
+ + Q K M ES G I+NISS + + + Y++SKA V A +++ +E
Sbjct: 158 ITSVVKMTQLILKHM-ESRQKGLILNISSGIALFPWPLYSMYSASKAFVCAFSKALQEEY 216
Query: 633 GKFNIRVNAILPGFIDTPIIK 695
+ + + P + T + K
Sbjct: 217 KAKEVIIQVLTPYAVSTAMTK 237
>AK026196-1|BAB15390.1| 181|Homo sapiens protein ( Homo sapiens
cDNA: FLJ22543 fis, clone HSI00212. ).
Length = 181
Score = 52.4 bits (120), Expect = 2e-06
Identities = 37/123 (30%), Positives = 66/123 (53%), Gaps = 5/123 (4%)
Frame = +3
Query: 366 IIVNSAGITRDNWMLKLSEEDYDSVLNVNLKGTFLVMQAFAKAMAESSV-TGSIINISSI 542
I +N+AG+ R + +L S + + NVN+ + + ++M E +V G IINI+S+
Sbjct: 14 ICINNAGLARPDTLLSGSTSGWKDMFNVNVLALSICTREAYQSMKERNVDDGHIININSM 73
Query: 543 VG-KYGNMGQTN-YASSKAGVVAMTQSAAKEL--GKFNIRVNAILPGFIDTPIIKTVPDK 710
G + + T+ Y+++K V A+T+ +EL + +IR I PG ++T + DK
Sbjct: 74 SGHRVLPLSVTHFYSATKYAVTALTEGLRQELREAQTHIRATCISPGVVETQFAFKLHDK 133
Query: 711 VKE 719
E
Sbjct: 134 DPE 136
>DQ325464-1|ABC61320.1| 244|Homo sapiens NADP(H)-dependent retinol
dehydrogenase/reductase B1 isoform protein.
Length = 244
Score = 52.0 bits (119), Expect = 2e-06
Identities = 33/96 (34%), Positives = 52/96 (54%), Gaps = 1/96 (1%)
Frame = +3
Query: 435 SVLNVNLKGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQ 614
+ L++N+K L+ +A M E GS++ +SSI + G + Y SK ++ +T+
Sbjct: 102 TTLDINVKAPALMTKAVVPEM-EKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTK 160
Query: 615 SAAKELGKFNIRVNAILPGFIDTPIIKTV-PDKVKE 719
+ A EL NIRVN + PG I T + + DK KE
Sbjct: 161 TLAIELAPRNIRVNCLAPGLIKTSFSRMLWMDKEKE 196
Score = 34.7 bits (76), Expect = 0.35
Identities = 16/46 (34%), Positives = 28/46 (60%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKT 236
+ ++ALVT + GIG A + L+++GA V+ + RK + Q + T
Sbjct: 30 LANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVAT 75
>BC012043-1|AAH12043.1| 312|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 12 protein.
Length = 312
Score = 51.2 bits (117), Expect = 4e-06
Identities = 54/205 (26%), Positives = 94/205 (45%), Gaps = 7/205 (3%)
Frame = +3
Query: 102 VGRLALVTGAGSGIGRAACQVLSKEGATVIAADR---KYEAAVQTIKTHTALAPGTNGGE 272
+G A+VTG+ GIG++ + L+K G V+ R K + IK +
Sbjct: 49 LGEWAVVTGSTDGIGKSYAEELAKHGMKVVLISRSKDKLDQVSSEIKEKFKV-------- 100
Query: 273 EHSAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVL--- 443
E + +D + S+ + D ++ L + I+VN+ G++ + L D D+V+
Sbjct: 101 ETRTIAVDFA-SEDIYDKIKTGLAGLEIG--ILVNNVGMSYEYPEYFLDVPDLDNVIKKM 157
Query: 444 -NVNLKGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSA 620
N+N+ + Q M E S G+I+NISS G T Y+++K V +Q
Sbjct: 158 ININILSVCKMTQLVLPGMVERS-KGAILNISSGSGMLPVPLLTIYSATKTFVDFFSQCL 216
Query: 621 AKELGKFNIRVNAILPGFIDTPIIK 695
+E + V ++LP F+ T + K
Sbjct: 217 HEEYRSKGVFVQSVLPYFVATKLAK 241
>AK222881-1|BAD96601.1| 312|Homo sapiens steroid dehydrogenase
homolog protein.
Length = 312
Score = 51.2 bits (117), Expect = 4e-06
Identities = 54/205 (26%), Positives = 94/205 (45%), Gaps = 7/205 (3%)
Frame = +3
Query: 102 VGRLALVTGAGSGIGRAACQVLSKEGATVIAADR---KYEAAVQTIKTHTALAPGTNGGE 272
+G A+VTG+ GIG++ + L+K G V+ R K + IK +
Sbjct: 49 LGEWAVVTGSTDGIGKSYAEELAKHGMKVVLISRSKDKLDQVSSEIKEKFKV-------- 100
Query: 273 EHSAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVL--- 443
E + +D + S+ + D ++ L + I+VN+ G++ + L D D+V+
Sbjct: 101 ETRTIAVDFA-SEDIYDKIKTGLAGLEIG--ILVNNVGMSYEYPEYFLDVPDLDNVIKKM 157
Query: 444 -NVNLKGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSA 620
N+N+ + Q M E S G+I+NISS G T Y+++K V +Q
Sbjct: 158 ININILSVCKMTQLVLPGMVERS-KGAILNISSGSGMLPVPLLTIYSATKTFVDFFSQCL 216
Query: 621 AKELGKFNIRVNAILPGFIDTPIIK 695
+E + V ++LP F+ T + K
Sbjct: 217 HEEYRSKGVFVQSVLPYFVATKLAK 241
>M76665-1|AAC31757.1| 292|Homo sapiens 11-beta-hydroxysteroid
dehydrogenase protein.
Length = 292
Score = 50.8 bits (116), Expect = 5e-06
Identities = 56/201 (27%), Positives = 89/201 (44%), Gaps = 5/201 (2%)
Frame = +3
Query: 96 LVVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEE 275
++ G+ +VTGA GIGR L+K GA V+ R E +Q + +H L G
Sbjct: 31 MLQGKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSKE-TLQKVVSH-CLELGAASAHY 88
Query: 276 HSAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSV---LN 446
+ D++ + V K +I+N IT N L L +D V +
Sbjct: 89 IAGTMEDMT---FAEQFVAQAGKLMGGLDMLILNH--IT--NTSLNLFHDDIHHVRKSME 141
Query: 447 VNLKGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAK 626
VN +++V+ A M + S GSI+ +SS+ GK Y++SK + S K
Sbjct: 142 VNFL-SYVVLTVAALPMLKQS-NGSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRK 199
Query: 627 E--LGKFNIRVNAILPGFIDT 683
E + + N+ + + G IDT
Sbjct: 200 EYSVSRVNVSITLCVLGLIDT 220
>BC012593-1|AAH12593.1| 292|Homo sapiens hydroxysteroid (11-beta)
dehydrogenase 1 protein.
Length = 292
Score = 50.8 bits (116), Expect = 5e-06
Identities = 56/201 (27%), Positives = 89/201 (44%), Gaps = 5/201 (2%)
Frame = +3
Query: 96 LVVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEE 275
++ G+ +VTGA GIGR L+K GA V+ R E +Q + +H L G
Sbjct: 31 MLQGKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSKE-TLQKVVSH-CLELGAASAHY 88
Query: 276 HSAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSV---LN 446
+ D++ + V K +I+N IT N L L +D V +
Sbjct: 89 IAGTMEDMT---FAEQFVAQAGKLMGGLDMLILNH--IT--NTSLNLFHDDIHHVRKSME 141
Query: 447 VNLKGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAK 626
VN +++V+ A M + S GSI+ +SS+ GK Y++SK + S K
Sbjct: 142 VNFL-SYVVLTVAALPMLKQS-NGSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRK 199
Query: 627 E--LGKFNIRVNAILPGFIDT 683
E + + N+ + + G IDT
Sbjct: 200 EYSVSRVNVSITLCVLGLIDT 220
>AY044084-1|AAK83653.1| 292|Homo sapiens 11-beta hydroxysteroid
dehydrogenase type 1 protein.
Length = 292
Score = 50.8 bits (116), Expect = 5e-06
Identities = 56/201 (27%), Positives = 89/201 (44%), Gaps = 5/201 (2%)
Frame = +3
Query: 96 LVVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEE 275
++ G+ +VTGA GIGR L+K GA V+ R E +Q + +H L G
Sbjct: 31 MLQGKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSKE-TLQKVVSH-CLELGAASAHY 88
Query: 276 HSAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSV---LN 446
+ D++ + V K +I+N IT N L L +D V +
Sbjct: 89 IAGTMEDMT---FAEQFVAQAGKLMGGLDMLILNH--IT--NTSLNLFHDDIHHVRKSME 141
Query: 447 VNLKGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAK 626
VN +++V+ A M + S GSI+ +SS+ GK Y++SK + S K
Sbjct: 142 VNFL-SYVVLTVAALPMLKQS-NGSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRK 199
Query: 627 E--LGKFNIRVNAILPGFIDT 683
E + + N+ + + G IDT
Sbjct: 200 EYSVSRVNVSITLCVLGLIDT 220
>AL031316-4|CAI20063.1| 292|Homo sapiens hydroxysteroid (11-beta)
dehydrogenase 1 protein.
Length = 292
Score = 50.8 bits (116), Expect = 5e-06
Identities = 56/201 (27%), Positives = 89/201 (44%), Gaps = 5/201 (2%)
Frame = +3
Query: 96 LVVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEE 275
++ G+ +VTGA GIGR L+K GA V+ R E +Q + +H L G
Sbjct: 31 MLQGKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSKE-TLQKVVSH-CLELGAASAHY 88
Query: 276 HSAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSV---LN 446
+ D++ + V K +I+N IT N L L +D V +
Sbjct: 89 IAGTMEDMT---FAEQFVAQAGKLMGGLDMLILNH--IT--NTSLNLFHDDIHHVRKSME 141
Query: 447 VNLKGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAK 626
VN +++V+ A M + S GSI+ +SS+ GK Y++SK + S K
Sbjct: 142 VNFL-SYVVLTVAALPMLKQS-NGSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRK 199
Query: 627 E--LGKFNIRVNAILPGFIDT 683
E + + N+ + + G IDT
Sbjct: 200 EYSVSRVNVSITLCVLGLIDT 220
>AL022398-8|CAA18541.2| 292|Homo sapiens hydroxysteroid (11-beta)
dehydrogenase 1 protein.
Length = 292
Score = 50.8 bits (116), Expect = 5e-06
Identities = 56/201 (27%), Positives = 89/201 (44%), Gaps = 5/201 (2%)
Frame = +3
Query: 96 LVVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEE 275
++ G+ +VTGA GIGR L+K GA V+ R E +Q + +H L G
Sbjct: 31 MLQGKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSKE-TLQKVVSH-CLELGAASAHY 88
Query: 276 HSAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSV---LN 446
+ D++ + V K +I+N IT N L L +D V +
Sbjct: 89 IAGTMEDMT---FAEQFVAQAGKLMGGLDMLILNH--IT--NTSLNLFHDDIHHVRKSME 141
Query: 447 VNLKGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAK 626
VN +++V+ A M + S GSI+ +SS+ GK Y++SK + S K
Sbjct: 142 VNFL-SYVVLTVAALPMLKQS-NGSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRK 199
Query: 627 E--LGKFNIRVNAILPGFIDT 683
E + + N+ + + G IDT
Sbjct: 200 EYSVSRVNVSITLCVLGLIDT 220
>AF229845-1|AAF63160.1| 311|Homo sapiens photoreceptor outer
segment all-trans retinol dehydrogenase protein.
Length = 311
Score = 50.0 bits (114), Expect = 9e-06
Identities = 51/195 (26%), Positives = 90/195 (46%), Gaps = 3/195 (1%)
Frame = +3
Query: 108 RLALVTGAGSGIGRAACQVLS---KEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEH 278
R L++G SGIG L+ K+ V+A R +T++ A G G+
Sbjct: 6 RTVLISGCSSGIGLELAVQLAHDPKKRYQVVATMRDL-GKKETLEA----AAGEALGQTL 60
Query: 279 SAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLK 458
+ +LDV + ++V + + ++VN+AG+ + LS +V + N
Sbjct: 61 TVAQLDVCSDESVAQCLSCIQGEVD----VLVNNAGMGLVGPLEGLSLAAMQNVFDTNFF 116
Query: 459 GTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELGK 638
G +++A M G I+ ISS++G G + YA+SK + +S A +L +
Sbjct: 117 GAVRLVKAVLPGMKRRR-QGHIVVISSVMGLQGVIFNDVYAASKFALEGFFESLAIQLLQ 175
Query: 639 FNIRVNAILPGFIDT 683
FNI ++ + PG + T
Sbjct: 176 FNIFISLVEPGPVVT 190
>DQ426886-1|ABD90542.1| 171|Homo sapiens retinol dehydrogenase 11
protein.
Length = 171
Score = 49.2 bits (112), Expect = 2e-05
Identities = 34/135 (25%), Positives = 69/135 (51%)
Frame = +3
Query: 105 GRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHSA 284
G++ +VTGA +GIG+ + L++ GA V A R E K T G ++
Sbjct: 41 GKVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKE----IQTTTGNQQVLV 96
Query: 285 VELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLKGT 464
+LD+S++K+++ + L + +K +++N+AG+ + + + ++ + VN G
Sbjct: 97 RKLDLSDTKSIRAFAKGFLAE-EKHLHVLINNAGVMMCPY--SKTADGFEMHIGVNHLGH 153
Query: 465 FLVMQAFAKAMAESS 509
FL+ + + ES+
Sbjct: 154 FLLTHLLLEKLKESA 168
>X13440-1|CAA31792.1| 328|Homo sapiens protein ( Human mRNA for
17-beta-hydroxysteroid dehydrogenase (17-HSD) (EC
1.1.1.62). ).
Length = 328
Score = 48.4 bits (110), Expect = 3e-05
Identities = 53/200 (26%), Positives = 94/200 (47%), Gaps = 3/200 (1%)
Frame = +3
Query: 111 LALVTGAGSGIG-RAACQVLS--KEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHS 281
+ L+TG SGIG A ++ S + V A R + + + ALA E
Sbjct: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLE--- 61
Query: 282 AVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLKG 461
++LDV +SK+V ++ + + + ++V +AG+ + L E+ SVL+VN+ G
Sbjct: 62 TLQLDVRDSKSVA-AARERVTEGRVD--VLVCNAGLGLLGPLEALGEDAVASVLDVNVVG 118
Query: 462 TFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELGKF 641
T ++QAF M +G ++ S+ G G Y +SK + + +S A L F
Sbjct: 119 TVRMLQAFLPDMKRRG-SGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPF 177
Query: 642 NIRVNAILPGFIDTPIIKTV 701
+ ++ I G + T ++ V
Sbjct: 178 GVHLSLIECGPVHTAFMEKV 197
>U34879-1|AAD05019.1| 328|Homo sapiens 17-beta-hydroxysteroid
dehydrogenase protein.
Length = 328
Score = 48.4 bits (110), Expect = 3e-05
Identities = 53/200 (26%), Positives = 94/200 (47%), Gaps = 3/200 (1%)
Frame = +3
Query: 111 LALVTGAGSGIG-RAACQVLS--KEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHS 281
+ L+TG SGIG A ++ S + V A R + + + ALA E
Sbjct: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLE--- 61
Query: 282 AVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLKG 461
++LDV +SK+V ++ + + + ++V +AG+ + L E+ SVL+VN+ G
Sbjct: 62 TLQLDVRDSKSVA-AARERVTEGRVD--VLVCNAGLGLLGPLEALGEDAVASVLDVNVVG 118
Query: 462 TFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELGKF 641
T ++QAF M +G ++ S+ G G Y +SK + + +S A L F
Sbjct: 119 TVRMLQAFLPDMKRRG-SGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPF 177
Query: 642 NIRVNAILPGFIDTPIIKTV 701
+ ++ I G + T ++ V
Sbjct: 178 GVHLSLIECGPVHTAFMEKV 197
>M84472-1|AAB16942.1| 328|Homo sapiens 17-beta-hydroxysteroid
dehydrogenase protein.
Length = 328
Score = 48.4 bits (110), Expect = 3e-05
Identities = 53/200 (26%), Positives = 94/200 (47%), Gaps = 3/200 (1%)
Frame = +3
Query: 111 LALVTGAGSGIG-RAACQVLS--KEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHS 281
+ L+TG SGIG A ++ S + V A R + + + ALA E
Sbjct: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLE--- 61
Query: 282 AVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLKG 461
++LDV +SK+V ++ + + + ++V +AG+ + L E+ SVL+VN+ G
Sbjct: 62 TLQLDVRDSKSVA-AARERVTEGRVD--VLVCNAGLGLLGPLEALGEDAVASVLDVNVVG 118
Query: 462 TFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELGKF 641
T ++QAF M +G ++ S+ G G Y +SK + + +S A L F
Sbjct: 119 TVRMLQAFLPDMKRRG-SGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPF 177
Query: 642 NIRVNAILPGFIDTPIIKTV 701
+ ++ I G + T ++ V
Sbjct: 178 GVHLSLIECGPVHTAFMEKV 197
>M36263-1|AAA35600.1| 328|Homo sapiens protein ( Human placental
17-beta-hydroxysteroid dehydrogenase mRNA, complete cds.
).
Length = 328
Score = 48.4 bits (110), Expect = 3e-05
Identities = 53/200 (26%), Positives = 94/200 (47%), Gaps = 3/200 (1%)
Frame = +3
Query: 111 LALVTGAGSGIG-RAACQVLS--KEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHS 281
+ L+TG SGIG A ++ S + V A R + + + ALA E
Sbjct: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLE--- 61
Query: 282 AVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLKG 461
++LDV +SK+V ++ + + + ++V +AG+ + L E+ SVL+VN+ G
Sbjct: 62 TLQLDVRDSKSVA-AARERVTEGRVD--VLVCNAGLGLLGPLEALGEDAVASVLDVNVVG 118
Query: 462 TFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELGKF 641
T ++QAF M +G ++ S+ G G Y +SK + + +S A L F
Sbjct: 119 TVRMLQAFLPDMKRRG-SGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPF 177
Query: 642 NIRVNAILPGFIDTPIIKTV 701
+ ++ I G + T ++ V
Sbjct: 178 GVHLSLIECGPVHTAFMEKV 197
>M27138-1|AAB16941.1| 328|Homo sapiens protein ( Human estradiol 17
beta-dehydrogenase gene, complete cds. ).
Length = 328
Score = 48.4 bits (110), Expect = 3e-05
Identities = 53/200 (26%), Positives = 94/200 (47%), Gaps = 3/200 (1%)
Frame = +3
Query: 111 LALVTGAGSGIG-RAACQVLS--KEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHS 281
+ L+TG SGIG A ++ S + V A R + + + ALA E
Sbjct: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLE--- 61
Query: 282 AVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLKG 461
++LDV +SK+V ++ + + + ++V +AG+ + L E+ SVL+VN+ G
Sbjct: 62 TLQLDVRDSKSVA-AARERVTEGRVD--VLVCNAGLGLLGPLEALGEDAVASVLDVNVVG 118
Query: 462 TFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELGKF 641
T ++QAF M +G ++ S+ G G Y +SK + + +S A L F
Sbjct: 119 TVRMLQAFLPDMKRRG-SGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPF 177
Query: 642 NIRVNAILPGFIDTPIIKTV 701
+ ++ I G + T ++ V
Sbjct: 178 GVHLSLIECGPVHTAFMEKV 197
>BC111935-1|AAI11936.1| 328|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 1 protein.
Length = 328
Score = 48.4 bits (110), Expect = 3e-05
Identities = 53/200 (26%), Positives = 94/200 (47%), Gaps = 3/200 (1%)
Frame = +3
Query: 111 LALVTGAGSGIG-RAACQVLS--KEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHS 281
+ L+TG SGIG A ++ S + V A R + + + ALA E
Sbjct: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLE--- 61
Query: 282 AVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLKG 461
++LDV +SK+V ++ + + + ++V +AG+ + L E+ SVL+VN+ G
Sbjct: 62 TLQLDVRDSKSVA-AARERVTEGRVD--VLVCNAGLGLLGPLEALGEDAVASVLDVNVVG 118
Query: 462 TFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELGKF 641
T ++QAF M +G ++ S+ G G Y +SK + + +S A L F
Sbjct: 119 TVRMLQAFLPDMKRRG-SGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPF 177
Query: 642 NIRVNAILPGFIDTPIIKTV 701
+ ++ I G + T ++ V
Sbjct: 178 GVHLSLIECGPVHTAFMEKV 197
>BC104752-1|AAI04753.1| 328|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 1 protein.
Length = 328
Score = 48.4 bits (110), Expect = 3e-05
Identities = 53/200 (26%), Positives = 94/200 (47%), Gaps = 3/200 (1%)
Frame = +3
Query: 111 LALVTGAGSGIG-RAACQVLS--KEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHS 281
+ L+TG SGIG A ++ S + V A R + + + ALA E
Sbjct: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLE--- 61
Query: 282 AVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLKG 461
++LDV +SK+V ++ + + + ++V +AG+ + L E+ SVL+VN+ G
Sbjct: 62 TLQLDVRDSKSVA-AARERVTEGRVD--VLVCNAGLGLLGPLEALGEDAVASVLDVNVVG 118
Query: 462 TFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKELGKF 641
T ++QAF M +G ++ S+ G G Y +SK + + +S A L F
Sbjct: 119 TVRMLQAFLPDMKRRG-SGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPF 177
Query: 642 NIRVNAILPGFIDTPIIKTV 701
+ ++ I G + T ++ V
Sbjct: 178 GVHLSLIECGPVHTAFMEKV 197
>BT019371-1|AAV38178.1| 260|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 3 protein.
Length = 260
Score = 48.0 bits (109), Expect = 4e-05
Identities = 47/179 (26%), Positives = 86/179 (48%), Gaps = 3/179 (1%)
Frame = +3
Query: 102 VGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHS 281
+G+ A++TGAG GIG+A L+K G V+ R E ++ I T G
Sbjct: 47 MGQWAVITGAGDGIGKAYSFELAKRGLNVVLISRTLE-KLEAIATEIE----RTTGRSVK 101
Query: 282 AVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRD---NWMLKLSEEDYDSVLNVN 452
++ D + + + +++ L + I+VN+ G+ + + L +E S+++ N
Sbjct: 102 IIQADFTKDD-IYEHIKEKLAGLEIG--ILVNNVGMLPNLLPSHFLNAPDE-IQSLIHCN 157
Query: 453 LKGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKE 629
+ + Q K M ES G I+NISS + + + Y++SKA V A +++ +E
Sbjct: 158 ITSVVKMTQLILKHM-ESRQKGLILNISSGIALFPWPLYSMYSASKAFVCAFSKALQEE 215
>BC002730-1|AAH02730.1| 302|Homo sapiens dehydrogenase/reductase
(SDR family) member 3 protein.
Length = 302
Score = 48.0 bits (109), Expect = 4e-05
Identities = 42/167 (25%), Positives = 73/167 (43%)
Frame = +3
Query: 117 LVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHSAVELD 296
L+TG G GIGR + ++ GA I + E ++ T GT E H + D
Sbjct: 42 LITGGGRGIGRQLAREFAERGARKIVLWGRTEKCLKE-TTEEIRQMGT---ECHYFI-CD 96
Query: 297 VSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLKGTFLVM 476
V N + V + +++ I+VN+A + ++ ++ ++N G F
Sbjct: 97 VGNREEVYQTAK-AVREKVGDITILVNNAAVVHGKSLMDSDDDALLKSQHINTLGQFWTT 155
Query: 477 QAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQS 617
+AF M E G I+ ++S++ G +Y +SKA A +S
Sbjct: 156 KAFLPRMLELQ-NGHIVCLNSVLALSAIPGAIDYCTSKASAFAFMES 201
>AL645761-1|CAI14999.1| 302|Homo sapiens dehydrogenase/reductase
(SDR family) member 3 protein.
Length = 302
Score = 48.0 bits (109), Expect = 4e-05
Identities = 42/167 (25%), Positives = 73/167 (43%)
Frame = +3
Query: 117 LVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHSAVELD 296
L+TG G GIGR + ++ GA I + E ++ T GT E H + D
Sbjct: 42 LITGGGRGIGRQLAREFAERGARKIVLWGRTEKCLKE-TTEEIRQMGT---ECHYFI-CD 96
Query: 297 VSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLKGTFLVM 476
V N + V + +++ I+VN+A + ++ ++ ++N G F
Sbjct: 97 VGNREEVYQTAK-AVREKVGDITILVNNAAVVHGKSLMDSDDDALLKSQHINTLGQFWTT 155
Query: 477 QAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQS 617
+AF M E G I+ ++S++ G +Y +SKA A +S
Sbjct: 156 KAFLPRMLELQ-NGHIVCLNSVLALSAIPGAIDYCTSKASAFAFMES 201
>AL513016-1|CAH74172.1| 302|Homo sapiens dehydrogenase/reductase
(SDR family) member 3 protein.
Length = 302
Score = 48.0 bits (109), Expect = 4e-05
Identities = 42/167 (25%), Positives = 73/167 (43%)
Frame = +3
Query: 117 LVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHSAVELD 296
L+TG G GIGR + ++ GA I + E ++ T GT E H + D
Sbjct: 42 LITGGGRGIGRQLAREFAERGARKIVLWGRTEKCLKE-TTEEIRQMGT---ECHYFI-CD 96
Query: 297 VSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLKGTFLVM 476
V N + V + +++ I+VN+A + ++ ++ ++N G F
Sbjct: 97 VGNREEVYQTAK-AVREKVGDITILVNNAAVVHGKSLMDSDDDALLKSQHINTLGQFWTT 155
Query: 477 QAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQS 617
+AF M E G I+ ++S++ G +Y +SKA A +S
Sbjct: 156 KAFLPRMLELQ-NGHIVCLNSVLALSAIPGAIDYCTSKASAFAFMES 201
>AK222593-1|BAD96313.1| 302|Homo sapiens dehydrogenase/reductase
(SDR family) member 3 variant protein.
Length = 302
Score = 48.0 bits (109), Expect = 4e-05
Identities = 42/167 (25%), Positives = 73/167 (43%)
Frame = +3
Query: 117 LVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHSAVELD 296
L+TG G GIGR + ++ GA I + E ++ T GT E H + D
Sbjct: 42 LITGGGRGIGRQLAREFAERGARKIVLWGRTEKCLKE-TTEEIRQMGT---ECHYFI-CD 96
Query: 297 VSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLKGTFLVM 476
V N + V + +++ I+VN+A + ++ ++ ++N G F
Sbjct: 97 VGNREEVYQTAK-AVREKVGDITILVNNAAVVHGKSLMDSDDDALLKSQHINTLGQFWTT 155
Query: 477 QAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQS 617
+AF M E G I+ ++S++ G +Y +SKA A +S
Sbjct: 156 KAFLPRMLELQ-NGHIVCLNSVLALSAIPGAIDYCTSKASAFAFMES 201
>AF179237-1|AAD55402.1| 302|Homo sapiens short-chain
dehydrogenase/reductase 1 protein.
Length = 302
Score = 48.0 bits (109), Expect = 4e-05
Identities = 42/167 (25%), Positives = 73/167 (43%)
Frame = +3
Query: 117 LVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHSAVELD 296
L+TG G GIGR + ++ GA I + E ++ T GT E H + D
Sbjct: 42 LITGGGRGIGRQLAREFAERGARKIVLWGRTEKCLKE-TTEEIRQMGT---ECHYFI-CD 96
Query: 297 VSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLKGTFLVM 476
V N + V + +++ I+VN+A + ++ ++ ++N G F
Sbjct: 97 VGNREEVYQTAK-AVREKVGDITILVNNAAVVHGKSLMDSDDDALLKSQHINTLGQFWTT 155
Query: 477 QAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQS 617
+AF M E G I+ ++S++ G +Y +SKA A +S
Sbjct: 156 KAFLPRMLELQ-NGHIVCLNSVLALSAIPGAIDYCTSKASAFAFMES 201
>AF061741-1|AAC63263.1| 302|Homo sapiens retinal short-chain
dehydrogenase/reductase retSDR1 protein.
Length = 302
Score = 48.0 bits (109), Expect = 4e-05
Identities = 42/167 (25%), Positives = 73/167 (43%)
Frame = +3
Query: 117 LVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHSAVELD 296
L+TG G GIGR + ++ GA I + E ++ T GT E H + D
Sbjct: 42 LITGGGRGIGRQLAREFAERGARKIVLWGRTEKCLKE-TTEEIRQMGT---ECHYFI-CD 96
Query: 297 VSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLKGTFLVM 476
V N + V + +++ I+VN+A + ++ ++ ++N G F
Sbjct: 97 VGNREEVYQTAK-AVREKVGDITILVNNAAVVHGKSLMDSDDDALLKSQHINTLGQFWTT 155
Query: 477 QAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQS 617
+AF M E G I+ ++S++ G +Y +SKA A +S
Sbjct: 156 KAFLPRMLELQ-NGHIVCLNSVLALSAIPGAIDYCTSKASAFAFMES 201
>DQ088988-1|AAZ85982.1| 118|Homo sapiens DHRS4L2 isoform 2 protein.
Length = 118
Score = 47.2 bits (107), Expect = 6e-05
Identities = 27/86 (31%), Positives = 47/86 (54%)
Frame = +3
Query: 405 MLKLSEEDYDSVLNVNLKGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYAS 584
++ ++EE +D L++N+K L+ +A M E GS++ +SSI + G + Y
Sbjct: 2 LMDVTEEVWDKTLDINVKAPALMTKAVVPEM-EKRGGGSVVIVSSIAAFSPSPGFSPYNV 60
Query: 585 SKAGVVAMTQSAAKELGKFNIRVNAI 662
SK ++ + + A EL NIRVN +
Sbjct: 61 SKTALLGLNNTLAIELAPRNIRVNCL 86
>Z97054-9|CAI42651.1| 169|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 10 protein.
Length = 169
Score = 46.0 bits (104), Expect = 1e-04
Identities = 48/169 (28%), Positives = 77/169 (45%), Gaps = 14/169 (8%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKY---EAAVQTIKTHTALAPGTNGG 269
V G +A++TG SG+G A + L +GA+ + D EA + + + AP
Sbjct: 8 VKGLVAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPA---- 63
Query: 270 EEHSAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGI--TRDNWMLKLSE----EDY 431
DV++ K VQ + ++ + + VN AGI + LK + ED+
Sbjct: 64 --------DVTSEKDVQTALALAKGKFGRVD-VAVNCAGIAVASKTYNLKKGQTHTLEDF 114
Query: 432 DSVLNVNLKGTFLVMQAFAKAMAES-----SVTGSIINISSIVGKYGNM 563
VL+VNL GTF V++ A M ++ G IIN +S+ G +
Sbjct: 115 QRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQV 163
>CR381696-2|CAI95410.1| 268|Homo sapiens dehydrogenase/reductase
(SDR family) X-linked protein.
Length = 268
Score = 45.2 bits (102), Expect = 2e-04
Identities = 50/218 (22%), Positives = 92/218 (42%), Gaps = 20/218 (9%)
Frame = +3
Query: 108 RLALVTGAGSGIGRAACQVLSKEGATVIAA---DRKYEAAVQTIKTHTALAPGTNGGEEH 278
R+A+VTG GIG + + L++ G VI A D K + V IK T ++
Sbjct: 44 RVAIVTGGTDGIGYSTAKHLARLGMHVIIAGNNDSKAKQVVSKIKEETL-------NDKV 96
Query: 279 SAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLK 458
+ D+++ +++ VQ K K P +++N+AG+ + + + ++ +N
Sbjct: 97 EFLYCDLASMTSIRQFVQ-KFKMKKIPLHVLINNAGVMM--VPQRKTRDGFEEHFGLNYL 153
Query: 459 GTFLVMQAFAKAMAESSVTG---SIINISSIVGKYGNMGQTN------------YASSKA 593
G FL+ + ES G ++ +SS + + YA SK
Sbjct: 154 GHFLLTNLLLDTLKESGSPGHSARVVTVSSATHYVAELNMDDLQSSACYSPHAAYAQSKL 213
Query: 594 GVVAMTQSAAKELGK--FNIRVNAILPGFIDTPIIKTV 701
+V T + L ++ N + PG ++T + K V
Sbjct: 214 ALVLFTYHLQRLLAAEGSHVTANVVDPGVVNTDVYKHV 251
>BX649443-2|CAI95431.1| 268|Homo sapiens dehydrogenase/reductase
(SDR family) X-linked protein.
Length = 268
Score = 45.2 bits (102), Expect = 2e-04
Identities = 50/218 (22%), Positives = 92/218 (42%), Gaps = 20/218 (9%)
Frame = +3
Query: 108 RLALVTGAGSGIGRAACQVLSKEGATVIAA---DRKYEAAVQTIKTHTALAPGTNGGEEH 278
R+A+VTG GIG + + L++ G VI A D K + V IK T ++
Sbjct: 44 RVAIVTGGTDGIGYSTAKHLARLGMHVIIAGNNDSKAKQVVSKIKEETL-------NDKV 96
Query: 279 SAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLK 458
+ D+++ +++ VQ K K P +++N+AG+ + + + ++ +N
Sbjct: 97 EFLYCDLASMTSIRQFVQ-KFKMKKIPLHVLINNAGVMM--VPQRKTRDGFEEHFGLNYL 153
Query: 459 GTFLVMQAFAKAMAESSVTG---SIINISSIVGKYGNMGQTN------------YASSKA 593
G FL+ + ES G ++ +SS + + YA SK
Sbjct: 154 GHFLLTNLLLDTLKESGSPGHSARVVTVSSATHYVAELNMDDLQSSACYSPHAAYAQSKL 213
Query: 594 GVVAMTQSAAKELGK--FNIRVNAILPGFIDTPIIKTV 701
+V T + L ++ N + PG ++T + K V
Sbjct: 214 ALVLFTYHLQRLLAAEGSHVTANVVDPGVVNTDVYKHV 251
>BC019696-1|AAH19696.2| 330|Homo sapiens DHRSX protein protein.
Length = 330
Score = 45.2 bits (102), Expect = 2e-04
Identities = 50/218 (22%), Positives = 92/218 (42%), Gaps = 20/218 (9%)
Frame = +3
Query: 108 RLALVTGAGSGIGRAACQVLSKEGATVIAA---DRKYEAAVQTIKTHTALAPGTNGGEEH 278
R+A+VTG GIG + + L++ G VI A D K + V IK T ++
Sbjct: 44 RVAIVTGGTDGIGYSTAKHLARLGMHVIIAGNNDSKAKQVVSKIKEETL-------NDKV 96
Query: 279 SAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLK 458
+ D+++ +++ VQ K K P +++N+AG+ + + + ++ +N
Sbjct: 97 EFLYCDLASMTSIRQFVQ-KFKMKKIPLHVLINNAGVMM--VPQRKTRDGFEEHFGLNYL 153
Query: 459 GTFLVMQAFAKAMAESSVTG---SIINISSIVGKYGNMGQTN------------YASSKA 593
G FL+ + ES G ++ +SS + + YA SK
Sbjct: 154 GHFLLTNLLLDTLKESGSPGHSARVVTVSSATHYVAELNMDDLQSSACYSPHAAYAQSKL 213
Query: 594 GVVAMTQSAAKELGK--FNIRVNAILPGFIDTPIIKTV 701
+V T + L ++ N + PG ++T + K V
Sbjct: 214 ALVLFTYHLQRLLAAEGSHVTANVVDPGVVNTDVYKHV 251
>AY358849-1|AAQ89208.1| 330|Homo sapiens ALTE protein.
Length = 330
Score = 45.2 bits (102), Expect = 2e-04
Identities = 50/218 (22%), Positives = 92/218 (42%), Gaps = 20/218 (9%)
Frame = +3
Query: 108 RLALVTGAGSGIGRAACQVLSKEGATVIAA---DRKYEAAVQTIKTHTALAPGTNGGEEH 278
R+A+VTG GIG + + L++ G VI A D K + V IK T ++
Sbjct: 44 RVAIVTGGTDGIGYSTAKHLARLGMHVIIAGNNDSKAKQVVSKIKEETL-------NDKV 96
Query: 279 SAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLK 458
+ D+++ +++ VQ K K P +++N+AG+ + + + ++ +N
Sbjct: 97 EFLYCDLASMTSIRQFVQ-KFKMKKIPLHVLINNAGVMM--VPQRKTRDGFEEHFGLNYL 153
Query: 459 GTFLVMQAFAKAMAESSVTG---SIINISSIVGKYGNMGQTN------------YASSKA 593
G FL+ + ES G ++ +SS + + YA SK
Sbjct: 154 GHFLLTNLLLDTLKESGSPGHSARVVTVSSATHYVAELNMDDLQSSACYSPHAAYAQSKL 213
Query: 594 GVVAMTQSAAKELGK--FNIRVNAILPGFIDTPIIKTV 701
+V T + L ++ N + PG ++T + K V
Sbjct: 214 ALVLFTYHLQRLLAAEGSHVTANVVDPGVVNTDVYKHV 251
>BC032340-1|AAH32340.1| 330|Homo sapiens dehydrogenase/reductase
(SDR family) X-linked protein.
Length = 330
Score = 44.8 bits (101), Expect = 3e-04
Identities = 50/218 (22%), Positives = 92/218 (42%), Gaps = 20/218 (9%)
Frame = +3
Query: 108 RLALVTGAGSGIGRAACQVLSKEGATVIAA---DRKYEAAVQTIKTHTALAPGTNGGEEH 278
R+A+VTG GIG + + L++ G VI A D K + V IK T ++
Sbjct: 44 RVAIVTGGTDGIGYSTAKHLARLGMHVIIAGNNDSKAKQVVSKIKEETL-------NDKV 96
Query: 279 SAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLK 458
+ D+++ +++ VQ K K P +++N+AG+ + + + ++ +N
Sbjct: 97 EFLYCDLASMTSIRQFVQ-KFKMKKIPLHVLINNAGVMM--VPQRKTRDGFEEHFGLNYL 153
Query: 459 GTFLVMQAFAKAMAESSVTG---SIINISSIVGKYGNMGQTN------------YASSKA 593
G FL+ + ES G ++ +SS + + YA SK
Sbjct: 154 GHFLLTNLLLDTLKESGSPGHSARVVTVSSATHYVAELNMDDLQSSACYSPHAAYAQSKL 213
Query: 594 GVVAMTQSAAKELGK--FNIRVNAILPGFIDTPIIKTV 701
+V T + L ++ N + PG ++T + K V
Sbjct: 214 ALVLFTYHLQRLLAAEGSHVTANVVDPGVVNTDLYKHV 251
>BC026024-1|AAH26024.1| 312|Homo sapiens DHRS12 protein protein.
Length = 312
Score = 44.8 bits (101), Expect = 3e-04
Identities = 51/212 (24%), Positives = 94/212 (44%), Gaps = 13/212 (6%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEH 278
+ GR+ LVTG SGIG+A ++K G TV R +A + + G H
Sbjct: 33 IPGRVFLVTGGNSGIGKATALEIAKRGGTVHLVCRD-QAPAEDARGEIIRESGNQNIFLH 91
Query: 279 SAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLK 458
+D+S+ K + V++ +++K +++N+AG + +L+E+ + N
Sbjct: 92 I---VDLSDPKQIWKFVENFKQEHKLH--VLINNAGCMVNK--RELTEDGLEKNFAANTL 144
Query: 459 GTFLVMQAFAKAMAESSVTGSIINISS---IVGKYGNM----------GQTNYASSKAGV 599
G +++ + E +I +SS +V K G YA +K
Sbjct: 145 GVYILTTGLIPVL-EKEHDPRVITVSSGGMLVQKLNTNDLQSERTPFDGTMVYAQNKRQQ 203
Query: 600 VAMTQSAAKELGKFNIRVNAILPGFIDTPIIK 695
V +T+ A+ G I +++ PG+ DTP ++
Sbjct: 204 VVLTERWAQ--GHPAIHFSSMHPGWADTPGVR 233
>AJ293620-1|CAC82170.1| 330|Homo sapiens putative oxidoreductase
protein.
Length = 330
Score = 44.8 bits (101), Expect = 3e-04
Identities = 50/218 (22%), Positives = 92/218 (42%), Gaps = 20/218 (9%)
Frame = +3
Query: 108 RLALVTGAGSGIGRAACQVLSKEGATVIAA---DRKYEAAVQTIKTHTALAPGTNGGEEH 278
R+A+VTG GIG + + L++ G VI A D K + V IK T ++
Sbjct: 44 RVAIVTGGTDGIGYSTAKHLARLGMHVIIAGNNDSKAKQVVSKIKEETL-------NDKV 96
Query: 279 SAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLK 458
+ D+++ +++ VQ K K P +++N+AG+ + + + ++ +N
Sbjct: 97 EFLYCDLASMTSIRQFVQ-KFKMKKIPLHVLINNAGVMM--VPQRKTRDGFEEHFGLNYL 153
Query: 459 GTFLVMQAFAKAMAESSVTG---SIINISSIVGKYGNMGQTN------------YASSKA 593
G FL+ + ES G ++ +SS + + YA SK
Sbjct: 154 GHFLLTNLLLDTLKESGSPGHSARVVTVSSATHYVAELNMDDLQSSACYSPHAAYAQSKL 213
Query: 594 GVVAMTQSAAKELGK--FNIRVNAILPGFIDTPIIKTV 701
+V T + L ++ N + PG ++T + K V
Sbjct: 214 ALVLFTYHLQRLLAAEGSHVTANVVDPGVVNTDLYKHV 251
>BC009881-1|AAH09881.1| 260|Homo sapiens retinol dehydrogenase 13
(all-trans/9-cis) protein.
Length = 260
Score = 44.4 bits (100), Expect = 4e-04
Identities = 37/151 (24%), Positives = 74/151 (49%), Gaps = 14/151 (9%)
Frame = +3
Query: 279 SAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITR-DNWMLKLSEEDYDSVLNVNL 455
+A LD+++ K++++ +++ ++ I++N+AG+ R +W +E+ ++ VN
Sbjct: 21 NARHLDLASLKSIREFAAKIIEEEERVD-ILINNAGVMRCPHWT---TEDGFEMQFGVNH 76
Query: 456 KGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMG------QTN-------YASSKAG 596
G FL+ + ++S IIN+SS+ G++ QT Y SK
Sbjct: 77 LGHFLLTNLLLDKL-KASAPSRIINLSSLAHVAGHIDFDDLNWQTRKYNTKAAYCQSKLA 135
Query: 597 VVAMTQSAAKELGKFNIRVNAILPGFIDTPI 689
+V T+ ++ L + VNA+ PG T +
Sbjct: 136 IVLFTKELSRRLQGSGVTVNALHPGVARTEL 166
>U14631-1|AAA91969.1| 405|Homo sapiens 11 beta-hydroxysteroid
dehydrogenase type II protein.
Length = 405
Score = 44.0 bits (99), Expect = 6e-04
Identities = 48/204 (23%), Positives = 86/204 (42%), Gaps = 3/204 (1%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEH 278
V R L+TG SG G+ + L G TV+A + + I+ T +P
Sbjct: 80 VATRAVLITGCDSGFGKETAKKLDSMGFTVLATVLELNSP-GAIELRTCCSPRLR----- 133
Query: 279 SAVELDVSNSKAVQDLVQDTLKQYKKPPCI--IVNSAGITRDNWMLKLSE-EDYDSVLNV 449
+++D++ + L++ T K + + +VN+AG +LS + S + V
Sbjct: 134 -LLQMDLTKPGDISRLLEFT-KAHTTSTGLWGLVNNAGHNEVVADAELSPVATFRSCMEV 191
Query: 450 NLKGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKE 629
N G + + + S G I+ + S G Y +SKA V + + + E
Sbjct: 192 NFFGALELTKGLLPLLRSS--RGRIVTVGSPAGDMPYPCLGAYGTSKAAVALLMDTFSCE 249
Query: 630 LGKFNIRVNAILPGFIDTPIIKTV 701
L + ++V+ I PG T ++ V
Sbjct: 250 LLPWGVKVSIIQPGCFKTESVRNV 273
>U26726-1|AAC50356.1| 405|Homo sapiens 11-beta-hydroxysteroid
dehydrogenase type 2 protein.
Length = 405
Score = 42.7 bits (96), Expect = 0.001
Identities = 47/204 (23%), Positives = 86/204 (42%), Gaps = 3/204 (1%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEH 278
V R L+TG SG G+ + L G TV+A + + I+ T +P
Sbjct: 80 VATRAVLITGCDSGFGKETAKKLDSMGFTVLATVLELNSP-GAIELRTCCSPRLR----- 133
Query: 279 SAVELDVSNSKAVQDLVQDTLKQYKKPPCI--IVNSAGITRDNWMLKLSE-EDYDSVLNV 449
+++D++ + +++ T K + + +VN+AG +LS + S + V
Sbjct: 134 -LLQMDLTKPGDISRVLEFT-KAHTTSTGLWGLVNNAGHNEVVADAELSPVATFRSCMEV 191
Query: 450 NLKGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKE 629
N G + + + S G I+ + S G Y +SKA V + + + E
Sbjct: 192 NFFGALELTKGLLPLLRSS--RGRIVTVGSPAGDMPYPCLGAYGTSKAAVALLMDTFSCE 249
Query: 630 LGKFNIRVNAILPGFIDTPIIKTV 701
L + ++V+ I PG T ++ V
Sbjct: 250 LLPWGVKVSIIQPGCFKTESVRNV 273
>EF694683-1|ABS29267.1| 405|Homo sapiens hydroxysteroid (11-beta)
dehydrogenase 2 protein.
Length = 405
Score = 42.7 bits (96), Expect = 0.001
Identities = 47/204 (23%), Positives = 86/204 (42%), Gaps = 3/204 (1%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEH 278
V R L+TG SG G+ + L G TV+A + + I+ T +P
Sbjct: 80 VATRAVLITGCDSGFGKETAKKLDSMGFTVLATVLELNSP-GAIELRTCCSPRLR----- 133
Query: 279 SAVELDVSNSKAVQDLVQDTLKQYKKPPCI--IVNSAGITRDNWMLKLSE-EDYDSVLNV 449
+++D++ + +++ T K + + +VN+AG +LS + S + V
Sbjct: 134 -LLQMDLTKPGDISRVLEFT-KAHTTSTGLWGLVNNAGHNEVVADAELSPVATFRSCMEV 191
Query: 450 NLKGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKE 629
N G + + + S G I+ + S G Y +SKA V + + + E
Sbjct: 192 NFFGALELTKGLLPLLRSS--RGRIVTVGSPAGDMPYPCLGAYGTSKAAVALLMDTFSCE 249
Query: 630 LGKFNIRVNAILPGFIDTPIIKTV 701
L + ++V+ I PG T ++ V
Sbjct: 250 LLPWGVKVSIIQPGCFKTESVRNV 273
>BC064536-1|AAH64536.1| 405|Homo sapiens hydroxysteroid (11-beta)
dehydrogenase 2 protein.
Length = 405
Score = 42.7 bits (96), Expect = 0.001
Identities = 47/204 (23%), Positives = 86/204 (42%), Gaps = 3/204 (1%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEH 278
V R L+TG SG G+ + L G TV+A + + I+ T +P
Sbjct: 80 VATRAVLITGCDSGFGKETAKKLDSMGFTVLATVLELNSP-GAIELRTCCSPRLR----- 133
Query: 279 SAVELDVSNSKAVQDLVQDTLKQYKKPPCI--IVNSAGITRDNWMLKLSE-EDYDSVLNV 449
+++D++ + +++ T K + + +VN+AG +LS + S + V
Sbjct: 134 -LLQMDLTKPGDISRVLEFT-KAHTTSTGLWGLVNNAGHNEVVADAELSPVATFRSCMEV 191
Query: 450 NLKGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKE 629
N G + + + S G I+ + S G Y +SKA V + + + E
Sbjct: 192 NFFGALELTKGLLPLLRSS--RGRIVTVGSPAGDMPYPCLGAYGTSKAAVALLMDTFSCE 249
Query: 630 LGKFNIRVNAILPGFIDTPIIKTV 701
L + ++V+ I PG T ++ V
Sbjct: 250 LLPWGVKVSIIQPGCFKTESVRNV 273
>BC036780-1|AAH36780.1| 405|Homo sapiens hydroxysteroid (11-beta)
dehydrogenase 2 protein.
Length = 405
Score = 42.7 bits (96), Expect = 0.001
Identities = 47/204 (23%), Positives = 86/204 (42%), Gaps = 3/204 (1%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEH 278
V R L+TG SG G+ + L G TV+A + + I+ T +P
Sbjct: 80 VATRAVLITGCDSGFGKETAKKLDSMGFTVLATVLELNSP-GAIELRTCCSPRLR----- 133
Query: 279 SAVELDVSNSKAVQDLVQDTLKQYKKPPCI--IVNSAGITRDNWMLKLSE-EDYDSVLNV 449
+++D++ + +++ T K + + +VN+AG +LS + S + V
Sbjct: 134 -LLQMDLTKPGDISRVLEFT-KAHTTSTGLWGLVNNAGHNEVVADAELSPVATFRSCMEV 191
Query: 450 NLKGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKE 629
N G + + + S G I+ + S G Y +SKA V + + + E
Sbjct: 192 NFFGALELTKGLLPLLRSS--RGRIVTVGSPAGDMPYPCLGAYGTSKAAVALLMDTFSCE 249
Query: 630 LGKFNIRVNAILPGFIDTPIIKTV 701
L + ++V+ I PG T ++ V
Sbjct: 250 LLPWGVKVSIIQPGCFKTESVRNV 273
>U89281-1|AAB88252.1| 317|Homo sapiens oxidative 3 alpha
hydroxysteroid dehydrogenase protein.
Length = 317
Score = 42.3 bits (95), Expect = 0.002
Identities = 51/222 (22%), Positives = 94/222 (42%), Gaps = 3/222 (1%)
Frame = +3
Query: 27 ILLLRFCEFYTIF*IIQDNMVSGLVVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRK 206
+ L F Y + ++ V + + +TG SG G + L G V+AA
Sbjct: 3 LYLAAFVGLYYLLHWYRERQVVSHLQDKYVFITGCDSGFGNLLARQLDARGLRVLAACLT 62
Query: 207 YEAAVQTIKTHTALAPGTNGGEEHSAVELDVSNSKAVQDLVQDTLKQYKKPPCI--IVNS 380
+ A Q ++ T+ + V LDV+ +++ Q +K++ + +VN+
Sbjct: 63 DKGAEQ-LRGQTS--------DRLETVTLDVTKMESIAAATQ-WVKEHVGDRRLWGLVNN 112
Query: 381 AGITRDNWMLK-LSEEDYDSVLNVNLKGTFLVMQAFAKAMAESSVTGSIINISSIVGKYG 557
AGI + + L+ ED ++L VNL G V + + + G GK
Sbjct: 113 AGILTPITLCEWLNTEDSMNMLKVNLIGVIQVTLSMLPLVRRA--RGKNCQCLQHSGKSC 170
Query: 558 NMGQTNYASSKAGVVAMTQSAAKELGKFNIRVNAILPGFIDT 683
+ + Y SK GV A + +E+ F ++++ + PG+ T
Sbjct: 171 FLCR-GYCVSKYGVEAFSDILRREIQHFGVKISIVEPGYFRT 211
>U27317-1|AAB48544.1| 405|Homo sapiens 11 beta-hydroxysteroid
dehydrogenase 2 protein.
Length = 405
Score = 42.3 bits (95), Expect = 0.002
Identities = 47/204 (23%), Positives = 85/204 (41%), Gaps = 3/204 (1%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEH 278
V R L+TG SG G+ + L G TV+A + + I+ T +P
Sbjct: 80 VATRAVLITGCDSGFGKETAKKLDSMGFTVLATVLELNSP-GAIELRTCCSPRLR----- 133
Query: 279 SAVELDVSNSKAVQDLVQDTLKQYKKPPCI--IVNSAGITRDNWMLKLSE-EDYDSVLNV 449
+++D++ + ++ T K + + +VN+AG +LS + S + V
Sbjct: 134 -LLQMDLTKPGDISRFLEFT-KAHTTSTGLWGLVNNAGHNEVVADAELSPVATFRSCMEV 191
Query: 450 NLKGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQSAAKE 629
N G + + + S G I+ + S G Y +SKA V + + + E
Sbjct: 192 NFFGALELTKGLLPLLRSS--RGRIVTVGSPAGDMPYPCLGAYGTSKAAVALLMDTFSCE 249
Query: 630 LGKFNIRVNAILPGFIDTPIIKTV 701
L + ++V+ I PG T ++ V
Sbjct: 250 LLPWGVKVSIIQPGCFKTESVRNV 273
>AF177983-1|AAF29493.1| 72|Homo sapiens NAD+-dependent
15-hydroxyprostaglandin dehydrogenase protein.
Length = 72
Score = 41.9 bits (94), Expect = 0.002
Identities = 22/42 (52%), Positives = 26/42 (61%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQ 224
V G++ALVTGA GIGRA + L +GA V D EA VQ
Sbjct: 3 VNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQ 44
>M76231-1|AAA60314.1| 261|Homo sapiens sepiapterin reductase
protein.
Length = 261
Score = 40.7 bits (91), Expect = 0.005
Identities = 51/206 (24%), Positives = 90/206 (43%), Gaps = 12/206 (5%)
Frame = +3
Query: 102 VGR-LALVTGAGSGIGRAACQVLS---KEGATVIAADRKYEAAVQTIKTHTALAPGTNGG 269
+GR + L+TGA G GR +L+ G+ ++ + R EA ++ A G
Sbjct: 5 LGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEA----LRQLEAELGAERSG 60
Query: 270 EEHSAVELDVSNSKAVQDLVQDTLKQYKKPP----CIIVNSAGITRD--NWMLKLSEE-D 428
V D+ +Q L+ L++ +P +++N+AG D + LS+
Sbjct: 61 LRVVRVPADLGAEAGLQQLL-GALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQ 119
Query: 429 YDSVLNVNLKGTFLVMQAFAKAMAES-SVTGSIINISSIVGKYGNMGQTNYASSKAGVVA 605
++ +NL + + KA +S + +++NISS+ G Y + KA
Sbjct: 120 VNNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDM 179
Query: 606 MTQSAAKELGKFNIRVNAILPGFIDT 683
+ Q A E + N+RV PG +DT
Sbjct: 180 LFQVLALE--EPNVRVLNYAPGPLDT 203
>CR381696-3|CAI95411.1| 266|Homo sapiens dehydrogenase/reductase
(SDR family) X-linked protein.
Length = 266
Score = 40.7 bits (91), Expect = 0.005
Identities = 37/150 (24%), Positives = 69/150 (46%), Gaps = 6/150 (4%)
Frame = +3
Query: 108 RLALVTGAGSGIGRAACQVLSKEGATVIAA---DRKYEAAVQTIKTHTALAPGTNGGEEH 278
R+A+VTG GIG + + L++ G VI A D K + V IK T ++
Sbjct: 121 RVAIVTGGTDGIGYSTAKHLARLGMHVIIAGNNDSKAKQVVSKIKEETL-------NDKV 173
Query: 279 SAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLK 458
+ D+++ +++ VQ K K P +++N+AG+ + + + ++ +N
Sbjct: 174 EFLYCDLASMTSIRQFVQ-KFKMKKIPLHVLINNAGVMM--VPQRKTRDGFEEHFGLNYL 230
Query: 459 GTFLVMQAFAKAMAESSVTG---SIINISS 539
G FL+ + ES G ++ +SS
Sbjct: 231 GHFLLTNLLLDTLKESGSPGHSARVVTVSS 260
>BX649443-3|CAI95432.1| 266|Homo sapiens dehydrogenase/reductase
(SDR family) X-linked protein.
Length = 266
Score = 40.7 bits (91), Expect = 0.005
Identities = 37/150 (24%), Positives = 69/150 (46%), Gaps = 6/150 (4%)
Frame = +3
Query: 108 RLALVTGAGSGIGRAACQVLSKEGATVIAA---DRKYEAAVQTIKTHTALAPGTNGGEEH 278
R+A+VTG GIG + + L++ G VI A D K + V IK T ++
Sbjct: 121 RVAIVTGGTDGIGYSTAKHLARLGMHVIIAGNNDSKAKQVVSKIKEETL-------NDKV 173
Query: 279 SAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLK 458
+ D+++ +++ VQ K K P +++N+AG+ + + + ++ +N
Sbjct: 174 EFLYCDLASMTSIRQFVQ-KFKMKKIPLHVLINNAGVMM--VPQRKTRDGFEEHFGLNYL 230
Query: 459 GTFLVMQAFAKAMAESSVTG---SIINISS 539
G FL+ + ES G ++ +SS
Sbjct: 231 GHFLLTNLLLDTLKESGSPGHSARVVTVSS 260
>BC017310-1|AAH17310.1| 261|Homo sapiens sepiapterin reductase
(7,8-dihydrobiopterin:NADP+ oxidoreductase) protein.
Length = 261
Score = 40.7 bits (91), Expect = 0.005
Identities = 51/206 (24%), Positives = 90/206 (43%), Gaps = 12/206 (5%)
Frame = +3
Query: 102 VGR-LALVTGAGSGIGRAACQVLS---KEGATVIAADRKYEAAVQTIKTHTALAPGTNGG 269
+GR + L+TGA G GR +L+ G+ ++ + R EA ++ A G
Sbjct: 5 LGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEA----LRQLEAELGAERSG 60
Query: 270 EEHSAVELDVSNSKAVQDLVQDTLKQYKKPP----CIIVNSAGITRD--NWMLKLSEE-D 428
V D+ +Q L+ L++ +P +++N+AG D + LS+
Sbjct: 61 LRVVRVPADLGAEAGLQQLL-GALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQ 119
Query: 429 YDSVLNVNLKGTFLVMQAFAKAMAES-SVTGSIINISSIVGKYGNMGQTNYASSKAGVVA 605
++ +NL + + KA +S + +++NISS+ G Y + KA
Sbjct: 120 VNNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDM 179
Query: 606 MTQSAAKELGKFNIRVNAILPGFIDT 683
+ Q A E + N+RV PG +DT
Sbjct: 180 LFQVLALE--EPNVRVLNYAPGPLDT 203
>AY358566-1|AAQ88929.1| 377|Homo sapiens EALL419 protein.
Length = 377
Score = 39.9 bits (89), Expect = 0.009
Identities = 36/127 (28%), Positives = 61/127 (48%)
Frame = +3
Query: 93 GLVVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGE 272
G + GR A+VTGA SGIG+ L++ GA V+ A R E + +G
Sbjct: 32 GNLRGRTAVVTGANSGIGKMTALELARRGARVVLACRSQERG----EAAAFDLRQESGNN 87
Query: 273 EHSAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVN 452
E + LD+++ +V+ L + I++++AGI+ + E ++ +L VN
Sbjct: 88 EVIFMALDLASLASVRAFATAFLSSEPRLD-ILIHNAGIS----SCGRTREAFNLLLRVN 142
Query: 453 LKGTFLV 473
G FL+
Sbjct: 143 HIGPFLL 149
>AF325432-1|AAL05449.1| 414|Homo sapiens WW domain-containing
oxidoreductase isoform FORII protein.
Length = 414
Score = 39.5 bits (88), Expect = 0.012
Identities = 38/145 (26%), Positives = 65/145 (44%)
Frame = +3
Query: 105 GRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHSA 284
G++ +VTGA SGIG + + GA VI A R A + + L E A
Sbjct: 124 GKVVVVTGANSGIGFETAKSFALHGAHVILACRNMARASEAVS--RILEEWHKAKVE--A 179
Query: 285 VELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLKGT 464
+ LD++ ++VQ + K P ++V +A W L+++ ++ VN G
Sbjct: 180 MTLDLALLRSVQHFA-EAFKAKNVPLHVLVCNAATFALPW--SLTKDGLETTFQVNHLGH 236
Query: 465 FLVMQAFAKAMAESSVTGSIINISS 539
F ++Q + S+ +I +SS
Sbjct: 237 FYLVQLLQDVLCRSA-PARVIVVSS 260
>AF211943-1|AAF27049.1| 414|Homo sapiens WW domain-containing
protein WWOX protein.
Length = 414
Score = 39.5 bits (88), Expect = 0.012
Identities = 38/145 (26%), Positives = 65/145 (44%)
Frame = +3
Query: 105 GRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHSA 284
G++ +VTGA SGIG + + GA VI A R A + + L E A
Sbjct: 124 GKVVVVTGANSGIGFETAKSFALHGAHVILACRNMARASEAVS--RILEEWHKAKVE--A 179
Query: 285 VELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLKGT 464
+ LD++ ++VQ + K P ++V +A W L+++ ++ VN G
Sbjct: 180 MTLDLALLRSVQHFA-EAFKAKNVPLHVLVCNAATFALPW--SLTKDGLETTFQVNHLGH 236
Query: 465 FLVMQAFAKAMAESSVTGSIINISS 539
F ++Q + S+ +I +SS
Sbjct: 237 FYLVQLLQDVLCRSA-PARVIVVSS 260
>AK024022-1|BAB14782.1| 219|Homo sapiens protein ( Homo sapiens
cDNA FLJ13960 fis, clone Y79AA1001233, weakly similar to
ESTRADIOL 17 BETA-DEHYDROGENASE 1 (EC 1.1.1.62). ).
Length = 219
Score = 39.1 bits (87), Expect = 0.016
Identities = 27/90 (30%), Positives = 45/90 (50%)
Frame = +3
Query: 414 LSEEDYDSVLNVNLKGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKA 593
LS +V + N G +++A M G I+ ISS++G G + YA+SK
Sbjct: 10 LSLAAMQNVFDTNFFGAVRLVKAVLPGMKRRR-QGHIVVISSVMGLQGVIFNDVYAASKF 68
Query: 594 GVVAMTQSAAKELGKFNIRVNAILPGFIDT 683
+ +S A +L +FNI ++ + PG + T
Sbjct: 69 ALEGFFESLAIQLLQFNIFISLVEPGPVVT 98
>AY444559-1|AAS68535.1| 265|Homo sapiens retinal short chain
dehydrogenase reductase isoform 1 protein.
Length = 265
Score = 38.7 bits (86), Expect = 0.022
Identities = 28/96 (29%), Positives = 42/96 (43%)
Frame = +3
Query: 99 VVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEH 278
V G + L+TGAGSG+GR ++ G+ ++ D E +T K +A H
Sbjct: 38 VAGEIVLITGAGSGLGRLLALQFARLGSVLVLWDINKEGNEETCK----MAREAGATRVH 93
Query: 279 SAVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAG 386
A D S + V + T K + P +I N G
Sbjct: 94 -AYTCDCSQKEGVYRVADQTYKAFL--PAMIANDHG 126
>AB209653-1|BAD92890.1| 166|Homo sapiens dehydrogenase/reductase
(SDR family) member 2 isoform 2 variant protein.
Length = 166
Score = 38.7 bits (86), Expect = 0.022
Identities = 17/40 (42%), Positives = 29/40 (72%)
Frame = +3
Query: 93 GLVVGRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYE 212
G++ R+A+VTG+ SGIG A + L+++GA V+ + RK +
Sbjct: 49 GVLANRVAVVTGSTSGIGFAIARRLARDGAHVVISSRKQQ 88
>AY256821-1|AAP94227.1| 526|Homo sapiens WOX8 isoform 8 protein.
Length = 526
Score = 37.9 bits (84), Expect = 0.038
Identities = 37/145 (25%), Positives = 64/145 (44%)
Frame = +3
Query: 105 GRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHSA 284
G++ +VTGA SGIG + + GA VI A R A + + L E
Sbjct: 124 GKVVVVTGANSGIGFETAKSFALHGAHVILACRNMARASEAVS--RILEEWHKAKVE--T 179
Query: 285 VELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLKGT 464
+ LD++ ++VQ + K P ++V +A W L+++ ++ VN G
Sbjct: 180 MTLDLALLRSVQHFA-EAFKAKNVPLHVLVCNAATFALPW--SLTKDGLETTFQVNHLGH 236
Query: 465 FLVMQAFAKAMAESSVTGSIINISS 539
F ++Q + S+ +I +SS
Sbjct: 237 FYLVQLLQDVLCRSA-PARVIVVSS 260
>AF227527-1|AAF82054.1| 414|Homo sapiens FOR II protein protein.
Length = 414
Score = 37.9 bits (84), Expect = 0.038
Identities = 37/145 (25%), Positives = 64/145 (44%)
Frame = +3
Query: 105 GRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHSA 284
G++ +VTGA SGIG + + GA VI A R A + + L E
Sbjct: 124 GKVVVVTGANSGIGFETAKSFALHGAHVILACRNMARASEAVS--RILEEWHKAKVE--T 179
Query: 285 VELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLKGT 464
+ LD++ ++VQ + K P ++V +A W L+++ ++ VN G
Sbjct: 180 MTLDLALLRSVQHFA-EAFKAKNVPLHVLVCNAATFALPW--SLTKDGLETTFQVNHLGH 236
Query: 465 FLVMQAFAKAMAESSVTGSIINISS 539
F ++Q + S+ +I +SS
Sbjct: 237 FYLVQLLQDVLCRSA-PARVIVVSS 260
>AF227526-1|AAF82053.1| 363|Homo sapiens FOR I protein protein.
Length = 363
Score = 37.9 bits (84), Expect = 0.038
Identities = 37/145 (25%), Positives = 64/145 (44%)
Frame = +3
Query: 105 GRLALVTGAGSGIGRAACQVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHSA 284
G++ +VTGA SGIG + + GA VI A R A + + L E
Sbjct: 124 GKVVVVTGANSGIGFETAKSFALHGAHVILACRNMARASEAVS--RILEEWHKAKVE--T 179
Query: 285 VELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGITRDNWMLKLSEEDYDSVLNVNLKGT 464
+ LD++ ++VQ + K P ++V +A W L+++ ++ VN G
Sbjct: 180 MTLDLALLRSVQHFA-EAFKAKNVPLHVLVCNAATFALPW--SLTKDGLETTFQVNHLGH 236
Query: 465 FLVMQAFAKAMAESSVTGSIINISS 539
F ++Q + S+ +I +SS
Sbjct: 237 FYLVQLLQDVLCRSA-PARVIVVSS 260
>AF162767-1|AAF14537.1| 341|Homo sapiens 17beta-hydroxysteroid
dehydrogenase type 7 protein.
Length = 341
Score = 37.1 bits (82), Expect = 0.066
Identities = 26/95 (27%), Positives = 52/95 (54%), Gaps = 1/95 (1%)
Frame = +3
Query: 108 RLALVTGAGSGIGRAAC-QVLSKEGATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHSA 284
++ L+TGA SGIG A C ++L+++ + + + + + +P T E +
Sbjct: 3 KVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASPTT---AEVTI 59
Query: 285 VELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGI 389
V +DVSN ++V ++ +++++ CI +N AGI
Sbjct: 60 VPVDVSNLQSVFRASKELKQRFQRLDCIYLN-AGI 93
>AK027882-1|BAB55429.1| 177|Homo sapiens protein ( Homo sapiens
cDNA FLJ14976 fis, clone THYRO1001406, highly similar to
PUTATIVE STEROID DEHYDROGENASE KIK-I (EC 1.1.1.-). ).
Length = 177
Score = 36.3 bits (80), Expect = 0.12
Identities = 25/86 (29%), Positives = 42/86 (48%)
Frame = +3
Query: 438 VLNVNLKGTFLVMQAFAKAMAESSVTGSIINISSIVGKYGNMGQTNYASSKAGVVAMTQS 617
++N+N+ + Q M E S G+I+NISS G T Y+++K V +Q
Sbjct: 22 MININILSVCKMTQLVLPGMVERS-KGAILNISSGSGMLPVPLLTIYSATKTFVDFFSQC 80
Query: 618 AAKELGKFNIRVNAILPGFIDTPIIK 695
+E + V ++LP F+ T + K
Sbjct: 81 LHEEYRSKGVFVQSVLPYFVATKLAK 106
>BT007075-1|AAP35738.1| 341|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 7 protein.
Length = 341
Score = 35.9 bits (79), Expect = 0.15
Identities = 30/96 (31%), Positives = 48/96 (50%), Gaps = 2/96 (2%)
Frame = +3
Query: 108 RLALVTGAGSGIGRAACQVLSKEG--ATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHS 281
++ L+TGA SGIG A C+ L E + A R A A P E +
Sbjct: 3 KVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTA----EVT 58
Query: 282 AVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGI 389
V++DVSN ++V ++ +++++ CI +N AGI
Sbjct: 59 IVQVDVSNLQSVFRASKELKQRFQRLDCIYLN-AGI 93
>BC065246-1|AAH65246.1| 341|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 7 protein.
Length = 341
Score = 35.9 bits (79), Expect = 0.15
Identities = 30/96 (31%), Positives = 48/96 (50%), Gaps = 2/96 (2%)
Frame = +3
Query: 108 RLALVTGAGSGIGRAACQVLSKEG--ATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHS 281
++ L+TGA SGIG A C+ L E + A R A A P E +
Sbjct: 3 KVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTA----EVT 58
Query: 282 AVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGI 389
V++DVSN ++V ++ +++++ CI +N AGI
Sbjct: 59 IVQVDVSNLQSVFRASKELKQRFQRLDCIYLN-AGI 93
>BC007068-1|AAH07068.1| 341|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 7 protein.
Length = 341
Score = 35.9 bits (79), Expect = 0.15
Identities = 30/96 (31%), Positives = 48/96 (50%), Gaps = 2/96 (2%)
Frame = +3
Query: 108 RLALVTGAGSGIGRAACQVLSKEG--ATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHS 281
++ L+TGA SGIG A C+ L E + A R A A P E +
Sbjct: 3 KVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTA----EVT 58
Query: 282 AVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGI 389
V++DVSN ++V ++ +++++ CI +N AGI
Sbjct: 59 IVQVDVSNLQSVFRASKELKQRFQRLDCIYLN-AGI 93
>AY358962-1|AAQ89321.1| 341|Homo sapiens HSD17B7 protein.
Length = 341
Score = 35.9 bits (79), Expect = 0.15
Identities = 30/96 (31%), Positives = 48/96 (50%), Gaps = 2/96 (2%)
Frame = +3
Query: 108 RLALVTGAGSGIGRAACQVLSKEG--ATVIAADRKYEAAVQTIKTHTALAPGTNGGEEHS 281
++ L+TGA SGIG A C+ L E + A R A A P E +
Sbjct: 3 KVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTA----EVT 58
Query: 282 AVELDVSNSKAVQDLVQDTLKQYKKPPCIIVNSAGI 389
V++DVSN ++V ++ +++++ CI +N AGI
Sbjct: 59 IVQVDVSNLQSVFRASKELKQRFQRLDCIYLN-AGI 93
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 110,376,162
Number of Sequences: 237096
Number of extensions: 2423642
Number of successful extensions: 5757
Number of sequences better than 10.0: 287
Number of HSP's better than 10.0 without gapping: 5337
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5580
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8847149012
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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