Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= bmmt27k02
(675 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X07994-1|CAA30801.1| 1927|Homo sapiens protein ( Human mRNA for ... 213 5e-55
M61850-1|AAA59504.1| 1927|Homo sapiens lactase phlorizinhydrolas... 213 5e-55
AY191611-1|AAP12677.1| 1003|Homo sapiens lactase-phlorizin hydro... 213 5e-55
AC011893-3|AAX88924.1| 1927|Homo sapiens unknown protein. 213 5e-55
BC101829-1|AAI01830.1| 469|Homo sapiens cytosolic beta-glucosid... 198 1e-50
AK222963-1|BAD96683.1| 469|Homo sapiens cytosolic beta-glucosid... 198 1e-50
AJ278964-1|CAC08178.1| 469|Homo sapiens cytosolic beta-glucosid... 198 1e-50
AF323990-1|AAL37305.1| 469|Homo sapiens cytosolic beta-glucosid... 198 1e-50
AB017913-1|BAB18741.1| 469|Homo sapiens cytosolic beta-glucosid... 198 1e-50
AF317840-1|AAG39217.1| 469|Homo sapiens cytosolic beta-glucosid... 197 3e-50
AY358729-1|AAQ89091.1| 567|Homo sapiens KPVW3022 protein. 191 2e-48
BC113653-1|AAI13654.1| 1044|Homo sapiens klotho beta protein. 176 7e-44
BC104871-1|AAI04872.1| 1044|Homo sapiens klotho beta protein. 176 7e-44
AB079373-1|BAC56857.1| 1044|Homo sapiens klotho beta like protei... 176 7e-44
AL161898-1|CAH71888.1| 1012|Homo sapiens klotho protein. 168 2e-41
AB009667-2|BAA24941.1| 549|Homo sapiens Klotho protein (KL) pro... 168 2e-41
AB009667-1|BAA24940.1| 1012|Homo sapiens Klotho protein (KL) pro... 168 2e-41
AB005142-1|BAA23382.1| 1012|Homo sapiens klotho protein. 168 2e-41
Z92540-2|CAC94767.1| 273|Homo sapiens 179I15.1 (klotho) protein. 163 5e-40
BC109377-1|AAI09378.1| 162|Homo sapiens GBA3 protein protein. 103 4e-22
BC029362-1|AAH29362.1| 162|Homo sapiens GBA3 protein protein. 103 4e-22
BC070188-1|AAH70188.1| 162|Homo sapiens GBA3 protein protein. 103 8e-22
Z84483-1|CAC94773.1| 739|Homo sapiens 46H23.1 (Klotho) protein. 72 2e-12
>X07994-1|CAA30801.1| 1927|Homo sapiens protein ( Human mRNA for
lactase-phlorizin hydrolase LPH (EC 3.2.1.23-62). ).
Length = 1927
Score = 213 bits (520), Expect = 5e-55
Identities = 92/200 (46%), Positives = 125/200 (62%)
Frame = +3
Query: 75 TFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWER 254
TF F +G +S++YQ+EGAW+ KG SIWD HT + D GD+ CDSYH +
Sbjct: 902 TFRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYHQLDA 961
Query: 255 DIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFHW 434
D+ M L + YRFS+SW R+ PTG ++ I+ G YYN LI+GL+ I P+VT+FHW
Sbjct: 962 DLNMLRALKVKAYRFSISWSRIFPTGRNSSINSHGVDYYNRLINGLVASNIFPMVTLFHW 1021
Query: 435 DLPQSLQDLGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEPVSICDYVYNTGGMAP 614
DLPQ+LQD+GGW NP ++D F+ YA F F DRVK W++ NEP+ + Y +G P
Sbjct: 1022 DLPQALQDIGGWENPALIDLFDSYADFCFQTFGDRVKFWMTFNEPMYLAWLGYGSGEFPP 1081
Query: 615 PIFEPHVAPYVCTKHVLLAH 674
+ +P APY V+ AH
Sbjct: 1082 GVKDPGWAPYRIAHTVIKAH 1101
Score = 201 bits (490), Expect = 2e-51
Identities = 96/200 (48%), Positives = 124/200 (62%), Gaps = 1/200 (0%)
Frame = +3
Query: 78 FPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWERD 257
FP GF + AASA+YQ+EGAW KG SIWD HT P + + GDV CDSYH D
Sbjct: 1377 FPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSHT-PLRVENDAIGDVACDSYHKIAED 1435
Query: 258 IEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFHWD 437
+ LG+ YRFS+SW R++P G + I+E G YY LID LL I+P VTI+HWD
Sbjct: 1436 LVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLAASIQPQVTIYHWD 1495
Query: 438 LPQSLQDLGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEPVSICDYVYNTGGMAPP 617
LPQ+LQD+GGW N IV F++YA V+F D+VK W+++NEP I Y G AP
Sbjct: 1496 LPQTLQDVGGWENETIVQRFKEYADVLFQRLGDKVKFWITLNEPFVIAYQGYGYGTAAPG 1555
Query: 618 IF-EPHVAPYVCTKHVLLAH 674
+ P APY+ +++ AH
Sbjct: 1556 VSNRPGTAPYIVGHNLIKAH 1575
Score = 180 bits (438), Expect = 4e-45
Identities = 92/204 (45%), Positives = 116/204 (56%), Gaps = 4/204 (1%)
Frame = +3
Query: 75 TFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNG----DVTCDSYH 242
TFP GF +GA++ ++ VEG W +G SIWD P ++ T G +V DSYH
Sbjct: 381 TFPEGFLWGASTGAFNVEGGWAEGGRGVSIWD------PRRPLNTTEGQATLEVASDSYH 434
Query: 243 LWERDIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVT 422
D+ + L Y+FS+SW R+ P G + S G YYN LID L D GIEP+ T
Sbjct: 435 KVASDVALLCGLRAQVYKFSISWSRIFPMGHGSSPSLPGVAYYNKLIDRLQDAGIEPMAT 494
Query: 423 IFHWDLPQSLQDLGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEPVSICDYVYNTG 602
+FHWDLPQ+LQD GGW N +VD F DYA FS F DRVK WV+ +EP + Y TG
Sbjct: 495 LFHWDLPQALQDHGGWQNESVVDAFLDYAAFCFSTFGDRVKLWVTFHEPWVMSYAGYGTG 554
Query: 603 GMAPPIFEPHVAPYVCTKHVLLAH 674
P I +P VA + VL AH
Sbjct: 555 QHPPGISDPGVASFKVAHLVLKAH 578
Score = 49.2 bits (112), Expect = 1e-05
Identities = 27/92 (29%), Positives = 40/92 (43%)
Frame = +3
Query: 291 YRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFHWDLPQSLQDLGGW 470
Y+ LSW +L+P G + E + Y L+ L ++P+V + H LP S
Sbjct: 87 YKVFLSWAQLLPAGSTQNPDEKTVQCYRRLLKALKTARLQPMVILHHQTLPASTLR---- 142
Query: 471 MNPLIVDWFEDYARVVFSLFADRVKTWVSINE 566
D F DYA F F D V W + ++
Sbjct: 143 RTEAFADLFADYATFAFHSFGDLVGIWFTFSD 174
>M61850-1|AAA59504.1| 1927|Homo sapiens lactase phlorizinhydrolase
protein.
Length = 1927
Score = 213 bits (520), Expect = 5e-55
Identities = 92/200 (46%), Positives = 125/200 (62%)
Frame = +3
Query: 75 TFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWER 254
TF F +G +S++YQ+EGAW+ KG SIWD HT + D GD+ CDSYH +
Sbjct: 902 TFRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYHQLDA 961
Query: 255 DIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFHW 434
D+ M L + YRFS+SW R+ PTG ++ I+ G YYN LI+GL+ I P+VT+FHW
Sbjct: 962 DLNMLRALKVKAYRFSISWSRIFPTGRNSSINSHGVDYYNRLINGLVASNIFPMVTLFHW 1021
Query: 435 DLPQSLQDLGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEPVSICDYVYNTGGMAP 614
DLPQ+LQD+GGW NP ++D F+ YA F F DRVK W++ NEP+ + Y +G P
Sbjct: 1022 DLPQALQDIGGWENPALIDLFDSYADFCFQTFGDRVKFWMTFNEPMYLAWLGYGSGEFPP 1081
Query: 615 PIFEPHVAPYVCTKHVLLAH 674
+ +P APY V+ AH
Sbjct: 1082 GVKDPGWAPYRIAHAVIKAH 1101
Score = 201 bits (490), Expect = 2e-51
Identities = 96/200 (48%), Positives = 124/200 (62%), Gaps = 1/200 (0%)
Frame = +3
Query: 78 FPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWERD 257
FP GF + AASA+YQ+EGAW KG SIWD HT P + + GDV CDSYH D
Sbjct: 1377 FPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSHT-PLRVENDAIGDVACDSYHKIAED 1435
Query: 258 IEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFHWD 437
+ LG+ YRFS+SW R++P G + I+E G YY LID LL I+P VTI+HWD
Sbjct: 1436 LVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLAASIQPQVTIYHWD 1495
Query: 438 LPQSLQDLGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEPVSICDYVYNTGGMAPP 617
LPQ+LQD+GGW N IV F++YA V+F D+VK W+++NEP I Y G AP
Sbjct: 1496 LPQTLQDVGGWENETIVQRFKEYADVLFQRLGDKVKFWITLNEPFVIAYQGYGYGTAAPG 1555
Query: 618 IF-EPHVAPYVCTKHVLLAH 674
+ P APY+ +++ AH
Sbjct: 1556 VSNRPGTAPYIVGHNLIKAH 1575
Score = 180 bits (438), Expect = 4e-45
Identities = 92/204 (45%), Positives = 116/204 (56%), Gaps = 4/204 (1%)
Frame = +3
Query: 75 TFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNG----DVTCDSYH 242
TFP GF +GA++ ++ VEG W +G SIWD P ++ T G +V DSYH
Sbjct: 381 TFPEGFLWGASTGAFNVEGGWAEGGRGVSIWD------PRRPLNTTEGQATLEVASDSYH 434
Query: 243 LWERDIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVT 422
D+ + L Y+FS+SW R+ P G + S G YYN LID L D GIEP+ T
Sbjct: 435 KVASDVALLCGLRAQVYKFSISWSRIFPMGHGSSPSLPGVAYYNKLIDRLQDAGIEPMAT 494
Query: 423 IFHWDLPQSLQDLGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEPVSICDYVYNTG 602
+FHWDLPQ+LQD GGW N +VD F DYA FS F DRVK WV+ +EP + Y TG
Sbjct: 495 LFHWDLPQALQDHGGWQNESVVDAFLDYAAFCFSTFGDRVKLWVTFHEPWVMSYAGYGTG 554
Query: 603 GMAPPIFEPHVAPYVCTKHVLLAH 674
P I +P VA + VL AH
Sbjct: 555 QHPPGISDPGVASFKVAHLVLKAH 578
Score = 49.2 bits (112), Expect = 1e-05
Identities = 27/92 (29%), Positives = 40/92 (43%)
Frame = +3
Query: 291 YRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFHWDLPQSLQDLGGW 470
Y+ LSW +L+P G + E + Y L+ L ++P+V + H LP S
Sbjct: 87 YKVFLSWAQLLPAGSTQNPDEKTVQCYRRLLKALKTARLQPMVILHHQTLPASTLR---- 142
Query: 471 MNPLIVDWFEDYARVVFSLFADRVKTWVSINE 566
D F DYA F F D V W + ++
Sbjct: 143 RTEAFADLFADYATFAFHSFGDLVGIWFTFSD 174
>AY191611-1|AAP12677.1| 1003|Homo sapiens lactase-phlorizin
hydrolase-1 protein.
Length = 1003
Score = 213 bits (520), Expect = 5e-55
Identities = 92/200 (46%), Positives = 125/200 (62%)
Frame = +3
Query: 75 TFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWER 254
TF F +G +S++YQ+EGAW+ KG SIWD HT + D GD+ CDSYH +
Sbjct: 334 TFRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYHQLDA 393
Query: 255 DIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFHW 434
D+ M L + YRFS+SW R+ PTG ++ I+ G YYN LI+GL+ I P+VT+FHW
Sbjct: 394 DLNMLRALKVKAYRFSISWSRIFPTGRNSSINSHGVDYYNRLINGLVASNIFPMVTLFHW 453
Query: 435 DLPQSLQDLGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEPVSICDYVYNTGGMAP 614
DLPQ+LQD+GGW NP ++D F+ YA F F DRVK W++ NEP+ + Y +G P
Sbjct: 454 DLPQALQDIGGWENPALIDLFDSYADFCFQTFGDRVKFWMTFNEPMYLAWLGYGSGEFPP 513
Query: 615 PIFEPHVAPYVCTKHVLLAH 674
+ +P APY V+ AH
Sbjct: 514 GVKDPGWAPYRIAHTVIKAH 533
Score = 191 bits (466), Expect = 2e-48
Identities = 90/179 (50%), Positives = 113/179 (63%)
Frame = +3
Query: 78 FPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWERD 257
FP GF + AASA+YQ+EGAW KG SIWD HT P + + GDV CDSYH D
Sbjct: 809 FPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSHT-PLRVENDAIGDVACDSYHKIAED 867
Query: 258 IEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFHWD 437
+ LG+ YRFS+SW R++P G + I+E G YY LID LL I+P VTI+HWD
Sbjct: 868 LVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLAASIQPQVTIYHWD 927
Query: 438 LPQSLQDLGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEPVSICDYVYNTGGMAP 614
LPQ+LQD+GGW N IV F++YA V+F D+VK W+++NEP I Y G AP
Sbjct: 928 LPQTLQDVGGWENETIVQRFKEYADVLFQRLGDKVKFWITLNEPFVIAYQGYGYGTAAP 986
>AC011893-3|AAX88924.1| 1927|Homo sapiens unknown protein.
Length = 1927
Score = 213 bits (520), Expect = 5e-55
Identities = 92/200 (46%), Positives = 125/200 (62%)
Frame = +3
Query: 75 TFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWER 254
TF F +G +S++YQ+EGAW+ KG SIWD HT + D GD+ CDSYH +
Sbjct: 902 TFRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYHQLDA 961
Query: 255 DIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFHW 434
D+ M L + YRFS+SW R+ PTG ++ I+ G YYN LI+GL+ I P+VT+FHW
Sbjct: 962 DLNMLRALKVKAYRFSISWSRIFPTGRNSSINSHGVDYYNRLINGLVASNIFPMVTLFHW 1021
Query: 435 DLPQSLQDLGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEPVSICDYVYNTGGMAP 614
DLPQ+LQD+GGW NP ++D F+ YA F F DRVK W++ NEP+ + Y +G P
Sbjct: 1022 DLPQALQDIGGWENPALIDLFDSYADFCFQTFGDRVKFWMTFNEPMYLAWLGYGSGEFPP 1081
Query: 615 PIFEPHVAPYVCTKHVLLAH 674
+ +P APY V+ AH
Sbjct: 1082 GVKDPGWAPYRIAHAVIKAH 1101
Score = 201 bits (490), Expect = 2e-51
Identities = 96/200 (48%), Positives = 124/200 (62%), Gaps = 1/200 (0%)
Frame = +3
Query: 78 FPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWERD 257
FP GF + AASA+YQ+EGAW KG SIWD HT P + + GDV CDSYH D
Sbjct: 1377 FPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSHT-PLRVENDAIGDVACDSYHKIAED 1435
Query: 258 IEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFHWD 437
+ LG+ YRFS+SW R++P G + I+E G YY LID LL I+P VTI+HWD
Sbjct: 1436 LVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLAASIQPQVTIYHWD 1495
Query: 438 LPQSLQDLGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEPVSICDYVYNTGGMAPP 617
LPQ+LQD+GGW N IV F++YA V+F D+VK W+++NEP I Y G AP
Sbjct: 1496 LPQTLQDVGGWENETIVQRFKEYADVLFQRLGDKVKFWITLNEPFVIAYQGYGYGTAAPG 1555
Query: 618 IF-EPHVAPYVCTKHVLLAH 674
+ P APY+ +++ AH
Sbjct: 1556 VSNRPGTAPYIVGHNLIKAH 1575
Score = 180 bits (438), Expect = 4e-45
Identities = 92/204 (45%), Positives = 116/204 (56%), Gaps = 4/204 (1%)
Frame = +3
Query: 75 TFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNG----DVTCDSYH 242
TFP GF +GA++ ++ VEG W +G SIWD P ++ T G +V DSYH
Sbjct: 381 TFPEGFLWGASTGAFNVEGGWAEGGRGVSIWD------PRRPLNTTEGQATLEVASDSYH 434
Query: 243 LWERDIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVT 422
D+ + L Y+FS+SW R+ P G + S G YYN LID L D GIEP+ T
Sbjct: 435 KVASDVALLCGLRAQVYKFSISWSRIFPMGHGSSPSLPGVAYYNKLIDRLQDAGIEPMAT 494
Query: 423 IFHWDLPQSLQDLGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEPVSICDYVYNTG 602
+FHWDLPQ+LQD GGW N +VD F DYA FS F DRVK WV+ +EP + Y TG
Sbjct: 495 LFHWDLPQALQDHGGWQNESVVDAFLDYAAFCFSTFGDRVKLWVTFHEPWVMSYAGYGTG 554
Query: 603 GMAPPIFEPHVAPYVCTKHVLLAH 674
P I +P VA + VL AH
Sbjct: 555 QHPPGISDPGVASFKVAHLVLKAH 578
Score = 49.2 bits (112), Expect = 1e-05
Identities = 27/92 (29%), Positives = 40/92 (43%)
Frame = +3
Query: 291 YRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFHWDLPQSLQDLGGW 470
Y+ LSW +L+P G + E + Y L+ L ++P+V + H LP S
Sbjct: 87 YKVFLSWAQLLPAGSTQNPDEKTVQCYRRLLKALKTARLQPMVILHHQTLPASTLR---- 142
Query: 471 MNPLIVDWFEDYARVVFSLFADRVKTWVSINE 566
D F DYA F F D V W + ++
Sbjct: 143 RTEAFADLFADYATFAFHSFGDLVGIWFTFSD 174
>BC101829-1|AAI01830.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 198 bits (484), Expect = 1e-50
Identities = 88/201 (43%), Positives = 123/201 (61%)
Frame = +3
Query: 72 LTFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWE 251
+ FP GF + AA+A+YQVEG W+ KG +WD H E + GDV C SY LWE
Sbjct: 1 MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWE 60
Query: 252 RDIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFH 431
D++ +LGL YRFSLSW RL+P G + I++ G YYN +ID LL G+ P+VT++H
Sbjct: 61 EDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYH 120
Query: 432 WDLPQSLQDLGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEPVSICDYVYNTGGMA 611
+DLPQ+L+D GGW++ I++ F+ YA+ FS F DRVK W++INE + Y+ G
Sbjct: 121 FDLPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFP 180
Query: 612 PPIFEPHVAPYVCTKHVLLAH 674
P I Y +++ AH
Sbjct: 181 PGIPHFGTGGYQAAHNLIKAH 201
>AK222963-1|BAD96683.1| 469|Homo sapiens cytosolic beta-glucosidase
variant protein.
Length = 469
Score = 198 bits (484), Expect = 1e-50
Identities = 88/201 (43%), Positives = 123/201 (61%)
Frame = +3
Query: 72 LTFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWE 251
+ FP GF + AA+A+YQVEG W+ KG +WD H E + GDV C SY LWE
Sbjct: 1 MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWE 60
Query: 252 RDIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFH 431
D++ +LGL YRFSLSW RL+P G + I++ G YYN +ID LL G+ P+VT++H
Sbjct: 61 EDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYH 120
Query: 432 WDLPQSLQDLGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEPVSICDYVYNTGGMA 611
+DLPQ+L+D GGW++ I++ F+ YA+ FS F DRVK W++INE + Y+ G
Sbjct: 121 FDLPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFP 180
Query: 612 PPIFEPHVAPYVCTKHVLLAH 674
P I Y +++ AH
Sbjct: 181 PGIPHFGTGGYQAAHNLIKAH 201
>AJ278964-1|CAC08178.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 198 bits (484), Expect = 1e-50
Identities = 88/201 (43%), Positives = 123/201 (61%)
Frame = +3
Query: 72 LTFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWE 251
+ FP GF + AA+A+YQVEG W+ KG +WD H E + GDV C SY LWE
Sbjct: 1 MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWE 60
Query: 252 RDIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFH 431
D++ +LGL YRFSLSW RL+P G + I++ G YYN +ID LL G+ P+VT++H
Sbjct: 61 EDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYH 120
Query: 432 WDLPQSLQDLGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEPVSICDYVYNTGGMA 611
+DLPQ+L+D GGW++ I++ F+ YA+ FS F DRVK W++INE + Y+ G
Sbjct: 121 FDLPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFP 180
Query: 612 PPIFEPHVAPYVCTKHVLLAH 674
P I Y +++ AH
Sbjct: 181 PGIPHFGTGGYQAAHNLIKAH 201
>AF323990-1|AAL37305.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 198 bits (484), Expect = 1e-50
Identities = 88/201 (43%), Positives = 123/201 (61%)
Frame = +3
Query: 72 LTFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWE 251
+ FP GF + AA+A+YQVEG W+ KG +WD H E + GDV C SY LWE
Sbjct: 1 MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWE 60
Query: 252 RDIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFH 431
D++ +LGL YRFSLSW RL+P G + I++ G YYN +ID LL G+ P+VT++H
Sbjct: 61 EDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYH 120
Query: 432 WDLPQSLQDLGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEPVSICDYVYNTGGMA 611
+DLPQ+L+D GGW++ I++ F+ YA+ FS F DRVK W++INE + Y+ G
Sbjct: 121 FDLPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFP 180
Query: 612 PPIFEPHVAPYVCTKHVLLAH 674
P I Y +++ AH
Sbjct: 181 PGIPHFGTGGYQAAHNLIKAH 201
>AB017913-1|BAB18741.1| 469|Homo sapiens cytosolic
beta-glucosidase-like protein-1 protein.
Length = 469
Score = 198 bits (484), Expect = 1e-50
Identities = 88/201 (43%), Positives = 123/201 (61%)
Frame = +3
Query: 72 LTFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWE 251
+ FP GF + AA+A+YQVEG W+ KG +WD H E + GDV C SY LWE
Sbjct: 1 MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWE 60
Query: 252 RDIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFH 431
D++ +LGL YRFSLSW RL+P G + I++ G YYN +ID LL G+ P+VT++H
Sbjct: 61 EDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYH 120
Query: 432 WDLPQSLQDLGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEPVSICDYVYNTGGMA 611
+DLPQ+L+D GGW++ I++ F+ YA+ FS F DRVK W++INE + Y+ G
Sbjct: 121 FDLPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFP 180
Query: 612 PPIFEPHVAPYVCTKHVLLAH 674
P I Y +++ AH
Sbjct: 181 PGIPHFGTGGYQAAHNLIKAH 201
>AF317840-1|AAG39217.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 197 bits (481), Expect = 3e-50
Identities = 88/201 (43%), Positives = 122/201 (60%)
Frame = +3
Query: 72 LTFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWE 251
+ FP GF + AA+A+YQVEG W+ KG +WD H E + GDV C SY LWE
Sbjct: 1 MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWE 60
Query: 252 RDIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFH 431
D++ +LGL YRFSLSW RL+P G + I++ G YYN +ID LL G+ P+VT++H
Sbjct: 61 EDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYH 120
Query: 432 WDLPQSLQDLGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEPVSICDYVYNTGGMA 611
+DLPQ+L+D GGW + I++ F+ YA+ FS F DRVK W++INE + Y+ G
Sbjct: 121 FDLPQTLEDQGGWWSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFP 180
Query: 612 PPIFEPHVAPYVCTKHVLLAH 674
P I Y +++ AH
Sbjct: 181 PGIPHFGTGGYQAAHNLIKAH 201
>AY358729-1|AAQ89091.1| 567|Homo sapiens KPVW3022 protein.
Length = 567
Score = 191 bits (465), Expect = 2e-48
Identities = 86/202 (42%), Positives = 124/202 (61%), Gaps = 2/202 (0%)
Frame = +3
Query: 75 TFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWER 254
TFP GF +G S++YQ EGAW+ KG SIWD H+ ++ DV CD Y+ +
Sbjct: 36 TFPLGFSWGVGSSAYQTEGAWDQDGKGPSIWDVFTHSGKGKVLGNETADVACDGYYKVQE 95
Query: 255 DIEMATELGLHFYRFSLSWPRLMPTGF-SNKISEDGQKYYNNLIDGLLDKGIEPLVTIFH 431
DI + EL ++ YRFSLSWPRL+PTG + ++++ G ++Y++LID LL I P+VT+ H
Sbjct: 96 DIILLRELHVNHYRFSLSWPRLLPTGIRAEQVNKKGIEFYSDLIDALLSSNITPIVTLHH 155
Query: 432 WDLPQSLQ-DLGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEPVSICDYVYNTGGM 608
WDLPQ LQ GGW N + ++F DYA + F F DRVK W++ ++P ++ + Y TG
Sbjct: 156 WDLPQLLQVKYGGWQNVSMANYFRDYANLCFEAFGDRVKHWITFSDPRAMAEKGYETGHH 215
Query: 609 APPIFEPHVAPYVCTKHVLLAH 674
AP + Y H++ AH
Sbjct: 216 APGLKLRGTGLYKAAHHIIKAH 237
>BC113653-1|AAI13654.1| 1044|Homo sapiens klotho beta protein.
Length = 1044
Score = 176 bits (428), Expect = 7e-44
Identities = 84/201 (41%), Positives = 119/201 (59%), Gaps = 1/201 (0%)
Frame = +3
Query: 75 TFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWER 254
TFP F +G + + QVEG+W KG SIWD +HT + + TNG + DSY E+
Sbjct: 80 TFPKNFFWGIGTGALQVEGSWKKDGKGPSIWDHFIHTHLKNVSS-TNG--SSDSYIFLEK 136
Query: 255 DIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFHW 434
D+ +G+ FY+FS+SWPRL P G + G +YY+ L+D L+ + IEP+VT++HW
Sbjct: 137 DLSALDFIGVSFYQFSISWPRLFPDGIVTVANAKGLQYYSTLLDALVLRNIEPIVTLYHW 196
Query: 435 DLPQSLQD-LGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEPVSICDYVYNTGGMA 611
DLP +LQ+ GGW N I+D F DYA F +F DRVK W++I+ P + + Y TG A
Sbjct: 197 DLPLALQEKYGGWKNDTIIDIFNDYATYCFQMFGDRVKYWITIHNPYLVAWHGYGTGMHA 256
Query: 612 PPIFEPHVAPYVCTKHVLLAH 674
P A Y +++ AH
Sbjct: 257 PGEKGNLAAVYTVGHNLIKAH 277
Score = 90.2 bits (214), Expect = 6e-18
Identities = 55/188 (29%), Positives = 91/188 (48%), Gaps = 12/188 (6%)
Frame = +3
Query: 78 FPPGFKFGAASASYQVEGAWN---VSDKGESIWD----RLVHTKPEAIMDLTNGDVTCDS 236
FP F +G + + E + SD +W+ RL+H + E + L C
Sbjct: 521 FPCDFSWGVTESVLKPESVASSPQFSDPHLYVWNATGNRLLH-RVEGVR-LKTRPAQCTD 578
Query: 237 YHLWERDIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPL 416
+ ++ +EM + + YRF+L W ++PTG + ++ +YY ++ L GI +
Sbjct: 579 FVNIKKQLEMLARMKVTHYRFALDWASVLPTGNLSAVNRQALRYYRCVVSEGLKLGISAM 638
Query: 417 VTIF-----HWDLPQSLQDLGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEPVSIC 581
VT++ H LP+ L GW+NP + F+ YA + F D VK W++INEP +
Sbjct: 639 VTLYYPTHAHLGLPEPLLHADGWLNPSTAEAFQAYAGLCFQELGDLVKLWITINEPNRLS 698
Query: 582 DYVYNTGG 605
D +YN G
Sbjct: 699 D-IYNRSG 705
>BC104871-1|AAI04872.1| 1044|Homo sapiens klotho beta protein.
Length = 1044
Score = 176 bits (428), Expect = 7e-44
Identities = 84/201 (41%), Positives = 119/201 (59%), Gaps = 1/201 (0%)
Frame = +3
Query: 75 TFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWER 254
TFP F +G + + QVEG+W KG SIWD +HT + + TNG + DSY E+
Sbjct: 80 TFPKNFFWGIGTGALQVEGSWKKDGKGPSIWDHFIHTHLKNVSS-TNG--SSDSYIFLEK 136
Query: 255 DIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFHW 434
D+ +G+ FY+FS+SWPRL P G + G +YY+ L+D L+ + IEP+VT++HW
Sbjct: 137 DLSALDFIGVSFYQFSISWPRLFPDGIVTVANAKGLQYYSTLLDALVLRNIEPIVTLYHW 196
Query: 435 DLPQSLQD-LGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEPVSICDYVYNTGGMA 611
DLP +LQ+ GGW N I+D F DYA F +F DRVK W++I+ P + + Y TG A
Sbjct: 197 DLPLALQEKYGGWKNDTIIDIFNDYATYCFQMFGDRVKYWITIHNPYLVAWHGYGTGMHA 256
Query: 612 PPIFEPHVAPYVCTKHVLLAH 674
P A Y +++ AH
Sbjct: 257 PGEKGNLAAVYTVGHNLIKAH 277
Score = 90.2 bits (214), Expect = 6e-18
Identities = 55/188 (29%), Positives = 91/188 (48%), Gaps = 12/188 (6%)
Frame = +3
Query: 78 FPPGFKFGAASASYQVEGAWN---VSDKGESIWD----RLVHTKPEAIMDLTNGDVTCDS 236
FP F +G + + E + SD +W+ RL+H + E + L C
Sbjct: 521 FPCDFSWGVTESVLKPESVASSPQFSDPHLYVWNATGNRLLH-RVEGVR-LKTRPAQCTD 578
Query: 237 YHLWERDIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPL 416
+ ++ +EM + + YRF+L W ++PTG + ++ +YY ++ L GI +
Sbjct: 579 FVNIKKQLEMLARMKVTHYRFALDWASVLPTGNLSAVNRQALRYYRCVVSEGLKLGISAM 638
Query: 417 VTIF-----HWDLPQSLQDLGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEPVSIC 581
VT++ H LP+ L GW+NP + F+ YA + F D VK W++INEP +
Sbjct: 639 VTLYYPTHAHLGLPEPLLHADGWLNPSTAEAFQAYAGLCFQELGDLVKLWITINEPNRLS 698
Query: 582 DYVYNTGG 605
D +YN G
Sbjct: 699 D-IYNRSG 705
>AB079373-1|BAC56857.1| 1044|Homo sapiens klotho beta like protein
protein.
Length = 1044
Score = 176 bits (428), Expect = 7e-44
Identities = 84/201 (41%), Positives = 119/201 (59%), Gaps = 1/201 (0%)
Frame = +3
Query: 75 TFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWER 254
TFP F +G + + QVEG+W KG SIWD +HT + + TNG + DSY E+
Sbjct: 80 TFPKNFFWGIGTGALQVEGSWKKDGKGPSIWDHFIHTHLKNVSS-TNG--SSDSYIFLEK 136
Query: 255 DIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPLVTIFHW 434
D+ +G+ FY+FS+SWPRL P G + G +YY+ L+D L+ + IEP+VT++HW
Sbjct: 137 DLSALDFIGVSFYQFSISWPRLFPDGIVTVANAKGLQYYSTLLDALVLRNIEPIVTLYHW 196
Query: 435 DLPQSLQD-LGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEPVSICDYVYNTGGMA 611
DLP +LQ+ GGW N I+D F DYA F +F DRVK W++I+ P + + Y TG A
Sbjct: 197 DLPLALQEKYGGWKNDTIIDIFNDYATYCFQMFGDRVKYWITIHNPYLVAWHGYGTGMHA 256
Query: 612 PPIFEPHVAPYVCTKHVLLAH 674
P A Y +++ AH
Sbjct: 257 PGEKGNLAAVYTVGHNLIKAH 277
Score = 90.2 bits (214), Expect = 6e-18
Identities = 55/188 (29%), Positives = 91/188 (48%), Gaps = 12/188 (6%)
Frame = +3
Query: 78 FPPGFKFGAASASYQVEGAWN---VSDKGESIWD----RLVHTKPEAIMDLTNGDVTCDS 236
FP F +G + + E + SD +W+ RL+H + E + L C
Sbjct: 521 FPCDFSWGVTESVLKPESVASSPQFSDPHLYVWNATGNRLLH-RVEGVR-LKTRPAQCTD 578
Query: 237 YHLWERDIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEPL 416
+ ++ +EM + + YRF+L W ++PTG + ++ +YY ++ L GI +
Sbjct: 579 FVNIKKQLEMLARMKVTHYRFALDWASVLPTGNLSAVNRQALRYYRCVVSEGLKLGISAM 638
Query: 417 VTIF-----HWDLPQSLQDLGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEPVSIC 581
VT++ H LP+ L GW+NP + F+ YA + F D VK W++INEP +
Sbjct: 639 VTLYYPTHAHLGLPEPLLHADGWLNPSTAEAFQAYAGLCFQELGDLVKLWITINEPNRLS 698
Query: 582 DYVYNTGG 605
D +YN G
Sbjct: 699 D-IYNRSG 705
>AL161898-1|CAH71888.1| 1012|Homo sapiens klotho protein.
Length = 1012
Score = 168 bits (408), Expect = 2e-41
Identities = 87/216 (40%), Positives = 118/216 (54%), Gaps = 16/216 (7%)
Frame = +3
Query: 75 TFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTN------------- 215
TFP GF + SA+YQ EG W KG SIWD H D N
Sbjct: 60 TFPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPLQP 119
Query: 216 --GDVTCDSYHLWERDIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDG 389
GDV DSY+ RD E ELG+ YRFS+SW R++P G + + +G +YY L++
Sbjct: 120 ATGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLER 179
Query: 390 LLDKGIEPLVTIFHWDLPQSLQD-LGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINE 566
L + G++P+VT++HWDLPQ LQD GGW N + D F DYA + F F +VK W++I+
Sbjct: 180 LRELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITIDN 239
Query: 567 PVSICDYVYNTGGMAPPIFEPHVAPYVCTKHVLLAH 674
P + + Y TG +AP I Y+ ++LLAH
Sbjct: 240 PYVVAWHGYATGRLAPGIRGSPRLGYLVAHNLLLAH 275
Score = 72.1 bits (169), Expect = 2e-12
Identities = 50/177 (28%), Positives = 81/177 (45%), Gaps = 12/177 (6%)
Frame = +3
Query: 75 TFPPGFKFGAASASYQVEGAWN-VSDKGESIWDRLVHTKPEAIMDLTNGDVT------CD 233
TFP F +G QV+ + +D +WD VH I +G VT C
Sbjct: 518 TFPCDFAWGVVDNYIQVDTTLSQFTDLNVYLWD--VHHSKRLIK--VDGVVTKKRKSYCV 573
Query: 234 SYHLWERDIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEP 413
+ + I + E+ + +RFSL W ++P G ++++ +YY + L+ I P
Sbjct: 574 DFAAIQPQIALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNITP 633
Query: 414 LVTIF-----HWDLPQSLQDLGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEP 569
+V ++ + LP+ L G W NP F +YAR+ F VK W+++NEP
Sbjct: 634 VVALWQPMAPNQGLPRLLARQGAWENPYTALAFAEYARLCFQELGHHVKLWITMNEP 690
>AB009667-2|BAA24941.1| 549|Homo sapiens Klotho protein (KL)
protein.
Length = 549
Score = 168 bits (408), Expect = 2e-41
Identities = 87/216 (40%), Positives = 118/216 (54%), Gaps = 16/216 (7%)
Frame = +3
Query: 75 TFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTN------------- 215
TFP GF + SA+YQ EG W KG SIWD H D N
Sbjct: 60 TFPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPLQP 119
Query: 216 --GDVTCDSYHLWERDIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDG 389
GDV DSY+ RD E ELG+ YRFS+SW R++P G + + +G +YY L++
Sbjct: 120 ATGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLER 179
Query: 390 LLDKGIEPLVTIFHWDLPQSLQD-LGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINE 566
L + G++P+VT++HWDLPQ LQD GGW N + D F DYA + F F +VK W++I+
Sbjct: 180 LRELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITIDN 239
Query: 567 PVSICDYVYNTGGMAPPIFEPHVAPYVCTKHVLLAH 674
P + + Y TG +AP I Y+ ++LLAH
Sbjct: 240 PYVVAWHGYATGRLAPGIRGSPRLGYLVAHNLLLAH 275
>AB009667-1|BAA24940.1| 1012|Homo sapiens Klotho protein (KL)
protein.
Length = 1012
Score = 168 bits (408), Expect = 2e-41
Identities = 87/216 (40%), Positives = 118/216 (54%), Gaps = 16/216 (7%)
Frame = +3
Query: 75 TFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTN------------- 215
TFP GF + SA+YQ EG W KG SIWD H D N
Sbjct: 60 TFPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPLQP 119
Query: 216 --GDVTCDSYHLWERDIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDG 389
GDV DSY+ RD E ELG+ YRFS+SW R++P G + + +G +YY L++
Sbjct: 120 ATGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLER 179
Query: 390 LLDKGIEPLVTIFHWDLPQSLQD-LGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINE 566
L + G++P+VT++HWDLPQ LQD GGW N + D F DYA + F F +VK W++I+
Sbjct: 180 LRELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITIDN 239
Query: 567 PVSICDYVYNTGGMAPPIFEPHVAPYVCTKHVLLAH 674
P + + Y TG +AP I Y+ ++LLAH
Sbjct: 240 PYVVAWHGYATGRLAPGIRGSPRLGYLVAHNLLLAH 275
Score = 72.1 bits (169), Expect = 2e-12
Identities = 50/177 (28%), Positives = 81/177 (45%), Gaps = 12/177 (6%)
Frame = +3
Query: 75 TFPPGFKFGAASASYQVEGAWN-VSDKGESIWDRLVHTKPEAIMDLTNGDVT------CD 233
TFP F +G QV+ + +D +WD VH I +G VT C
Sbjct: 518 TFPCDFAWGVVDNYIQVDTTLSQFTDLNVYLWD--VHHSKRLIK--VDGVVTKKRKSYCV 573
Query: 234 SYHLWERDIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEP 413
+ + I + E+ + +RFSL W ++P G ++++ +YY + L+ I P
Sbjct: 574 DFAAIQPQIALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNITP 633
Query: 414 LVTIF-----HWDLPQSLQDLGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEP 569
+V ++ + LP+ L G W NP F +YAR+ F VK W+++NEP
Sbjct: 634 VVALWQPMAPNQGLPRLLARQGAWENPYTALAFAEYARLCFQELGHHVKLWITMNEP 690
>AB005142-1|BAA23382.1| 1012|Homo sapiens klotho protein.
Length = 1012
Score = 168 bits (408), Expect = 2e-41
Identities = 87/216 (40%), Positives = 118/216 (54%), Gaps = 16/216 (7%)
Frame = +3
Query: 75 TFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTN------------- 215
TFP GF + SA+YQ EG W KG SIWD H D N
Sbjct: 60 TFPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPLQP 119
Query: 216 --GDVTCDSYHLWERDIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDG 389
GDV DSY+ RD E ELG+ YRFS+SW R++P G + + +G +YY L++
Sbjct: 120 ATGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLER 179
Query: 390 LLDKGIEPLVTIFHWDLPQSLQD-LGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINE 566
L + G++P+VT++HWDLPQ LQD GGW N + D F DYA + F F +VK W++I+
Sbjct: 180 LRELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITIDN 239
Query: 567 PVSICDYVYNTGGMAPPIFEPHVAPYVCTKHVLLAH 674
P + + Y TG +AP I Y+ ++LLAH
Sbjct: 240 PYVVAWHGYATGRLAPGIRGSPRLGYLVAHNLLLAH 275
Score = 72.1 bits (169), Expect = 2e-12
Identities = 50/177 (28%), Positives = 81/177 (45%), Gaps = 12/177 (6%)
Frame = +3
Query: 75 TFPPGFKFGAASASYQVEGAWN-VSDKGESIWDRLVHTKPEAIMDLTNGDVT------CD 233
TFP F +G QV+ + +D +WD VH I +G VT C
Sbjct: 518 TFPCDFAWGVVDNYIQVDTTLSQFTDLNVYLWD--VHHSKRLIK--VDGVVTKKRKSYCV 573
Query: 234 SYHLWERDIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEP 413
+ + I + E+ + +RFSL W ++P G ++++ +YY + L+ I P
Sbjct: 574 DFAAIQPQIALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNITP 633
Query: 414 LVTIF-----HWDLPQSLQDLGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEP 569
+V ++ + LP+ L G W NP F +YAR+ F VK W+++NEP
Sbjct: 634 VVALWQPMAPNQGLPRLLARQGAWENPYTALAFAEYARLCFQELGHHVKLWITMNEP 690
>Z92540-2|CAC94767.1| 273|Homo sapiens 179I15.1 (klotho) protein.
Length = 273
Score = 163 bits (396), Expect = 5e-40
Identities = 85/214 (39%), Positives = 116/214 (54%), Gaps = 16/214 (7%)
Frame = +3
Query: 75 TFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTN------------- 215
TFP GF + SA+YQ EG W KG SIWD H D N
Sbjct: 60 TFPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPLQP 119
Query: 216 --GDVTCDSYHLWERDIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDG 389
GDV DSY+ RD E ELG+ YRFS+SW R++P G + + +G +YY L++
Sbjct: 120 ATGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLER 179
Query: 390 LLDKGIEPLVTIFHWDLPQSLQD-LGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINE 566
L + G++P+VT++HWDLPQ LQD GGW N + D F DYA + F F +VK W++I+
Sbjct: 180 LRELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITIDN 239
Query: 567 PVSICDYVYNTGGMAPPIFEPHVAPYVCTKHVLL 668
P + + Y TG +AP I Y+ ++LL
Sbjct: 240 PYVVAWHGYATGRLAPGIRGSPRLGYLVAHNLLL 273
>BC109377-1|AAI09378.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 103 bits (248), Expect = 4e-22
Identities = 44/94 (46%), Positives = 58/94 (61%)
Frame = +3
Query: 72 LTFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWE 251
+ FP GF + AA+A+YQVEG W+ KG +WD H E + GDV C SY LWE
Sbjct: 1 MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWE 60
Query: 252 RDIEMATELGLHFYRFSLSWPRLMPTGFSNKISE 353
D++ +LGL YRFSLSW RL+P G + I++
Sbjct: 61 EDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQ 94
>BC029362-1|AAH29362.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 103 bits (248), Expect = 4e-22
Identities = 44/94 (46%), Positives = 58/94 (61%)
Frame = +3
Query: 72 LTFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWE 251
+ FP GF + AA+A+YQVEG W+ KG +WD H E + GDV C SY LWE
Sbjct: 1 MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWE 60
Query: 252 RDIEMATELGLHFYRFSLSWPRLMPTGFSNKISE 353
D++ +LGL YRFSLSW RL+P G + I++
Sbjct: 61 EDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQ 94
>BC070188-1|AAH70188.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 103 bits (246), Expect = 8e-22
Identities = 44/94 (46%), Positives = 58/94 (61%)
Frame = +3
Query: 72 LTFPPGFKFGAASASYQVEGAWNVSDKGESIWDRLVHTKPEAIMDLTNGDVTCDSYHLWE 251
+ FP GF + AA+A+YQVEG W+ KG +WD H E + GDV C SY LWE
Sbjct: 1 MAFPAGFGWAAATAAYQVEGGWDADGKGLCVWDTFTHQGGERVFKNQTGDVACGSYTLWE 60
Query: 252 RDIEMATELGLHFYRFSLSWPRLMPTGFSNKISE 353
D++ +LGL YRFSLSW RL+P G + I++
Sbjct: 61 EDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQ 94
>Z84483-1|CAC94773.1| 739|Homo sapiens 46H23.1 (Klotho) protein.
Length = 739
Score = 72.1 bits (169), Expect = 2e-12
Identities = 50/177 (28%), Positives = 81/177 (45%), Gaps = 12/177 (6%)
Frame = +3
Query: 75 TFPPGFKFGAASASYQVEGAWN-VSDKGESIWDRLVHTKPEAIMDLTNGDVT------CD 233
TFP F +G QV+ + +D +WD VH I +G VT C
Sbjct: 245 TFPCDFAWGVVDNYIQVDTTLSQFTDLNVYLWD--VHHSKRLIK--VDGVVTKKRKSYCV 300
Query: 234 SYHLWERDIEMATELGLHFYRFSLSWPRLMPTGFSNKISEDGQKYYNNLIDGLLDKGIEP 413
+ + I + E+ + +RFSL W ++P G ++++ +YY + L+ I P
Sbjct: 301 DFAAIQPQIALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNITP 360
Query: 414 LVTIF-----HWDLPQSLQDLGGWMNPLIVDWFEDYARVVFSLFADRVKTWVSINEP 569
+V ++ + LP+ L G W NP F +YAR+ F VK W+++NEP
Sbjct: 361 VVALWQPMAPNQGLPRLLARQGAWENPYTALAFAEYARLCFQELGHHVKLWITMNEP 417
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 107,835,965
Number of Sequences: 237096
Number of extensions: 2502470
Number of successful extensions: 12502
Number of sequences better than 10.0: 23
Number of HSP's better than 10.0 without gapping: 12288
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 12471
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 7615267504
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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