Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= bmmt27d19
(672 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
U31875-1|AAA82048.1| 280|Homo sapiens Hep27 protein protein. 92 2e-18
BC007339-1|AAH07339.2| 271|Homo sapiens DHRS2 protein protein. 92 2e-18
AF244132-1|AAG33703.1| 280|Homo sapiens short-chain alcohol deh... 92 2e-18
BC006294-1|AAH06294.1| 270|Homo sapiens hydroxysteroid (17-beta... 91 3e-18
BC006283-1|AAH06283.1| 270|Homo sapiens hydroxysteroid (17-beta... 91 3e-18
AY358430-1|AAQ88796.1| 270|Homo sapiens ATGT502 protein. 91 3e-18
AF126781-1|AAF06940.1| 270|Homo sapiens retinal short-chain deh... 91 3e-18
BC002786-1|AAH02786.1| 300|Homo sapiens dehydrogenase/reductase... 89 1e-17
AK222857-1|BAD96577.1| 280|Homo sapiens dehydrogenase/reductase... 89 1e-17
DQ344810-1|ABD75823.1| 278|Homo sapiens NADP(H)-dependent retin... 85 2e-16
BC003019-1|AAH03019.1| 278|Homo sapiens dehydrogenase/reductase... 85 2e-16
AY358638-1|AAQ89001.1| 278|Homo sapiens SCAD-SRL protein. 85 2e-16
AK001870-1|BAA91953.1| 278|Homo sapiens protein ( Homo sapiens ... 85 2e-16
AB045131-1|BAB18775.1| 260|Homo sapiens NADPH-dependent retinol... 85 2e-16
AF064256-1|AAQ13444.1| 278|Homo sapiens Hep27-like protein prot... 84 4e-16
AF044127-1|AAD02292.1| 260|Homo sapiens peroxisomal short-chain... 84 4e-16
BC007337-1|AAH07337.1| 339|Homo sapiens dehydrogenase/reductase... 79 1e-14
BC000637-1|AAH00637.1| 339|Homo sapiens dehydrogenase/reductase... 79 1e-14
AY359031-1|AAQ89390.1| 289|Homo sapiens oxidoreductase/S-2 H pr... 79 1e-14
AF151844-1|AAD34081.1| 339|Homo sapiens CGI-86 protein protein. 79 1e-14
AF126782-1|AAF06941.1| 289|Homo sapiens retinal short-chain deh... 79 1e-14
BC002529-1|AAH02529.1| 303|Homo sapiens peroxisomal trans-2-eno... 79 2e-14
AF232009-1|AAF69798.1| 303|Homo sapiens peroxisomal trans 2-eno... 79 2e-14
AF212234-1|AAK14920.1| 322|Homo sapiens HPDHase protein. 79 2e-14
AC010686-2|AAY14657.1| 303|Homo sapiens unknown protein. 79 2e-14
AJ250303-1|CAB89810.1| 303|Homo sapiens peroxisomal 2-enoyl-CoA... 78 2e-14
BC095414-1|AAH95414.1| 245|Homo sapiens 3-hydroxybutyrate dehyd... 75 2e-13
BC001953-1|AAH01953.1| 245|Homo sapiens 3-hydroxybutyrate dehyd... 75 2e-13
AF164790-1|AAF80754.1| 245|Homo sapiens oxidoreductase UCPA pro... 75 2e-13
AY358841-1|AAQ89200.1| 245|Homo sapiens GRLD6308 protein. 74 5e-13
BC033650-1|AAH33650.1| 237|Homo sapiens carbonyl reductase 4 pr... 73 9e-13
BC021973-1|AAH21973.1| 237|Homo sapiens carbonyl reductase 4 pr... 73 9e-13
AF151851-1|AAD34088.1| 291|Homo sapiens CGI-93 protein protein. 71 4e-12
CR457124-1|CAG33405.1| 325|Homo sapiens DKFZp566O084 protein. 70 9e-12
BC009679-1|AAH09679.1| 325|Homo sapiens dehydrogenase/reductase... 70 9e-12
BC004126-1|AAH04126.1| 325|Homo sapiens dehydrogenase/reductase... 70 9e-12
AY358498-1|AAQ88862.1| 310|Homo sapiens DFIT212 protein. 70 9e-12
AK027337-1|BAB55045.1| 179|Homo sapiens protein ( Homo sapiens ... 69 1e-11
BC000663-1|AAH00663.2| 230|Homo sapiens dehydrogenase/reductase... 63 1e-09
DQ325464-1|ABC61320.1| 244|Homo sapiens NADP(H)-dependent retin... 62 1e-09
BC015943-1|AAH15943.1| 313|Homo sapiens DHRS1 protein protein. 62 2e-09
BC014057-1|AAH14057.1| 313|Homo sapiens DHRS1 protein protein. 62 2e-09
AK058159-1|BAB71694.1| 313|Homo sapiens protein ( Homo sapiens ... 62 2e-09
AF418205-1|AAN32660.1| 313|Homo sapiens dehydrogenase/reductase... 62 2e-09
X63657-1|CAA45197.1| 332|Homo sapiens FVT1 protein. 61 3e-09
U26726-1|AAC50356.1| 405|Homo sapiens 11-beta-hydroxysteroid de... 61 3e-09
EF694683-1|ABS29267.1| 405|Homo sapiens hydroxysteroid (11-beta... 61 3e-09
BT006782-1|AAP35428.1| 332|Homo sapiens follicular lymphoma var... 61 3e-09
BC064536-1|AAH64536.1| 405|Homo sapiens hydroxysteroid (11-beta... 61 3e-09
BC036780-1|AAH36780.1| 405|Homo sapiens hydroxysteroid (11-beta... 61 3e-09
BC008797-1|AAH08797.1| 332|Homo sapiens follicular lymphoma var... 61 3e-09
U14631-1|AAA91969.1| 405|Homo sapiens 11 beta-hydroxysteroid de... 61 4e-09
M93107-1|AAA58352.1| 343|Homo sapiens (R)-3-hydroxybutyrate deh... 61 4e-09
BC019317-1|AAH19317.1| 343|Homo sapiens 3-hydroxybutyrate dehyd... 61 4e-09
BC011964-1|AAH11964.1| 343|Homo sapiens 3-hydroxybutyrate dehyd... 61 4e-09
BC005844-1|AAH05844.1| 343|Homo sapiens 3-hydroxybutyrate dehyd... 61 4e-09
U27317-1|AAB48544.1| 405|Homo sapiens 11 beta-hydroxysteroid de... 60 7e-09
BC036001-1|AAH36001.1| 300|Homo sapiens hydroxysteroid (17-beta... 60 9e-09
BC021673-1|AAH21673.1| 300|Homo sapiens hydroxysteroid (17-beta... 60 9e-09
BC016367-1|AAH16367.1| 300|Homo sapiens hydroxysteroid (17-beta... 60 9e-09
BC014327-1|AAH14327.1| 300|Homo sapiens hydroxysteroid (17-beta... 60 9e-09
AY358553-1|AAQ88917.1| 300|Homo sapiens KFLL207 protein. 60 9e-09
AK075348-1|BAC11560.1| 300|Homo sapiens protein ( Homo sapiens ... 60 9e-09
AF273056-1|AAM44459.1| 300|Homo sapiens CTCL tumor antigen HD-C... 60 9e-09
AF139841-1|AAP97273.1| 244|Homo sapiens carbonyl reductase II p... 60 9e-09
AF126780-1|AAF06939.1| 300|Homo sapiens retinal short-chain deh... 60 9e-09
BC104218-1|AAI04219.1| 330|Homo sapiens hydroxysteroid dehydrog... 59 1e-08
AY028377-1|AAK16927.1| 309|Homo sapiens steroid dehydrogenase-l... 59 1e-08
AK074878-1|BAC11262.1| 330|Homo sapiens protein ( Homo sapiens ... 59 1e-08
AF237684-1|AAK15047.1| 309|Homo sapiens steroid dehydrogenase-l... 59 1e-08
BT006881-1|AAP35527.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 58 3e-08
BC106917-1|AAI06918.1| 330|Homo sapiens hydroxysteroid dehydrog... 58 3e-08
BC104219-1|AAI04220.1| 330|Homo sapiens hydroxysteroid dehydrog... 58 3e-08
BC003018-1|AAH03018.1| 243|Homo sapiens Unknown (protein for IM... 58 3e-08
BC001470-1|AAH01470.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 58 3e-08
AF515625-1|AAM54026.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 58 3e-08
AF515624-1|AAO15991.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 58 3e-08
AF515623-1|AAN59786.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 58 3e-08
AF113123-1|AAF14864.1| 244|Homo sapiens carbonyl reductase prot... 58 3e-08
AB013846-1|BAB64299.1| 244|Homo sapiens kidney dicarbonyl reduc... 58 3e-08
M76665-1|AAC31757.1| 292|Homo sapiens 11-beta-hydroxysteroid de... 58 4e-08
BC012593-1|AAH12593.1| 292|Homo sapiens hydroxysteroid (11-beta... 58 4e-08
AY044084-1|AAK83653.1| 292|Homo sapiens 11-beta hydroxysteroid ... 58 4e-08
AL031316-4|CAI20063.1| 292|Homo sapiens hydroxysteroid (11-beta... 58 4e-08
AL022398-8|CAA18541.2| 292|Homo sapiens hydroxysteroid (11-beta... 58 4e-08
BC018084-1|AAH18084.2| 330|Homo sapiens hydroxysteroid dehydrog... 57 5e-08
BC008650-1|AAH08650.1| 300|Homo sapiens HSD17B11 protein protein. 57 5e-08
L76465-1|AAA89175.1| 266|Homo sapiens NAD+-dependent 15-hydroxy... 57 7e-08
J05594-1|AAA89174.1| 266|Homo sapiens NAD+-dependent 15-hydroxy... 57 7e-08
DQ903072-1|ABI75347.1| 266|Homo sapiens hydroxyprostaglandin de... 57 7e-08
BC018986-1|AAH18986.1| 266|Homo sapiens hydroxyprostaglandin de... 57 7e-08
X87176-1|CAA60643.1| 736|Homo sapiens 17beta-hydroxysteroid deh... 54 4e-07
BC003098-1|AAH03098.1| 736|Homo sapiens hydroxysteroid (17-beta... 54 4e-07
AF057740-1|AAD08652.1| 736|Homo sapiens 17-beta-hydroxysteroid ... 54 4e-07
BC002731-1|AAH02731.2| 260|Homo sapiens short-chain dehydrogena... 54 5e-07
AY358712-1|AAQ89074.1| 260|Homo sapiens ARPG836 protein. 54 5e-07
AY313894-1|AAP83166.1| 315|Homo sapiens short-chain dehydrogena... 54 6e-07
AY268352-1|AAP42286.1| 286|Homo sapiens short-chain dehydrogena... 54 6e-07
L40802-1|AAC41917.1| 387|Homo sapiens 17-hydroxysteroid dehydro... 52 1e-06
L11708-1|AAA03562.1| 387|Homo sapiens 17 beta hydroxysteroid de... 52 1e-06
BC095451-1|AAH95451.1| 418|Homo sapiens hydroxysteroid dehydrog... 52 1e-06
BC059170-1|AAH59170.1| 387|Homo sapiens hydroxysteroid (17-beta... 52 1e-06
BC009581-1|AAH09581.1| 387|Homo sapiens hydroxysteroid (17-beta... 52 1e-06
AY325910-1|AAP78485.1| 387|Homo sapiens hydroxysteroid (17-beta... 52 1e-06
AY093428-1|AAM14670.1| 418|Homo sapiens hydroxysteroid dehydrog... 52 1e-06
AL162732-1|CAM17152.1| 418|Homo sapiens hydroxysteroid dehydrog... 52 1e-06
AK223001-1|BAD96721.1| 387|Homo sapiens hydroxysteroid (17-beta... 52 1e-06
Z97054-8|CAI42653.1| 261|Homo sapiens hydroxysteroid (17-beta) ... 51 3e-06
U96132-1|AAC51812.1| 261|Homo sapiens amyloid beta-peptide bind... 51 3e-06
U73514-1|AAB68958.1| 261|Homo sapiens short-chain alcohol dehyd... 51 3e-06
CR456723-1|CAG33004.1| 261|Homo sapiens HADH2 protein. 51 3e-06
BC000372-1|AAH00372.1| 261|Homo sapiens hydroxysteroid (17-beta... 51 3e-06
AY092415-1|AAM18189.1| 196|Homo sapiens endoplasmic reticulum-a... 51 3e-06
AF069134-1|AAC39900.1| 261|Homo sapiens putative short-chain ty... 51 3e-06
AF037438-1|AAC16419.1| 261|Homo sapiens 17beta-hydroxysteroid d... 51 3e-06
AF035555-1|AAC15902.1| 261|Homo sapiens 17beta-hydroxysteroid d... 51 3e-06
AF229845-1|AAF63160.1| 311|Homo sapiens photoreceptor outer seg... 51 4e-06
CR457309-1|CAG33590.1| 173|Homo sapiens DHRS6 protein. 49 2e-05
BC037277-1|AAH37277.1| 173|Homo sapiens BDH2 protein protein. 49 2e-05
AY358473-1|AAQ88837.1| 331|Homo sapiens RDH13 protein. 49 2e-05
AK023323-1|BAB14526.1| 173|Homo sapiens protein ( Homo sapiens ... 49 2e-05
DQ088988-1|AAZ85982.1| 118|Homo sapiens DHRS4L2 isoform 2 protein. 48 4e-05
AK075392-1|BAC11591.1| 331|Homo sapiens protein ( Homo sapiens ... 48 4e-05
U43559-1|AAC50725.1| 318|Homo sapiens 11-cis retinol dehydrogen... 47 5e-05
BC028298-1|AAH28298.1| 318|Homo sapiens retinol dehydrogenase 5... 47 5e-05
AF037062-1|AAC09250.1| 318|Homo sapiens retinol dehydrogenase p... 47 5e-05
BC101553-1|AAI01554.1| 313|Homo sapiens orphan short-chain dehy... 47 7e-05
BC101551-1|AAI01552.1| 313|Homo sapiens orphan short-chain dehy... 47 7e-05
AY044434-1|AAK95856.1| 313|Homo sapiens retinol dehydrogenase s... 47 7e-05
BC020710-1|AAH20710.1| 317|Homo sapiens hydroxysteroid (17-beta... 46 1e-04
AF223225-1|AAF81017.1| 317|Homo sapiens 3-hydroxysteroid epimer... 46 1e-04
AF016509-1|AAB67236.1| 317|Homo sapiens oxidoreductase protein. 46 1e-04
X82460-1|CAA57843.1| 178|Homo sapiens 15-hydroxy prostaglandin ... 46 2e-04
U89281-1|AAB88252.1| 317|Homo sapiens oxidative 3 alpha hydroxy... 46 2e-04
U63296-1|AAB53034.1| 143|Homo sapiens 15-hydroxyprostaglandin d... 46 2e-04
BT007239-1|AAP35903.1| 261|Homo sapiens hydroxysteroid (17-beta... 44 4e-04
BC008185-1|AAH08185.1| 261|Homo sapiens hydroxysteroid (17-beta... 44 4e-04
AL844527-12|CAI41840.1| 261|Homo sapiens hydroxysteroid (17-bet... 44 4e-04
AL713971-6|CAI17657.1| 261|Homo sapiens hydroxysteroid (17-beta... 44 4e-04
AL662824-24|CAI17616.1| 261|Homo sapiens hydroxysteroid (17-bet... 44 4e-04
AL645940-10|CAI18068.1| 261|Homo sapiens hydroxysteroid (17-bet... 44 4e-04
AL031228-10|CAC38444.1| 261|Homo sapiens hydroxysteroid (17-bet... 44 4e-04
BC067131-1|AAH67131.1| 341|Homo sapiens retinol dehydrogenase 1... 44 5e-04
AY358270-1|AAQ88637.1| 341|Homo sapiens RDH10 protein. 44 5e-04
AF456765-1|AAN64747.1| 341|Homo sapiens retinol dehydrogenase 1... 44 5e-04
U89717-1|AAB93668.1| 318|Homo sapiens 9-cis-retinol specific de... 44 7e-04
BC002730-1|AAH02730.1| 302|Homo sapiens dehydrogenase/reductase... 44 7e-04
AL645761-1|CAI14999.1| 302|Homo sapiens dehydrogenase/reductase... 44 7e-04
AL513016-1|CAH74172.1| 302|Homo sapiens dehydrogenase/reductase... 44 7e-04
AK222593-1|BAD96313.1| 302|Homo sapiens dehydrogenase/reductase... 44 7e-04
AF179237-1|AAD55402.1| 302|Homo sapiens short-chain dehydrogena... 44 7e-04
AF061741-1|AAC63263.1| 302|Homo sapiens retinal short-chain deh... 44 7e-04
AF057034-1|AAC39922.1| 317|Homo sapiens sterol/retinol dehydrog... 44 7e-04
BC009881-1|AAH09881.1| 260|Homo sapiens retinol dehydrogenase 1... 43 9e-04
AF086735-1|AAC72923.1| 317|Homo sapiens retinol dehydrogenase p... 43 0.001
D82061-1|BAA11529.1| 259|Homo sapiens a member of the short-cha... 42 0.002
U78302-1|AAB88724.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase... 42 0.002
U49352-1|AAB09423.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase... 42 0.002
L26050-1|AAA67551.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase... 42 0.002
BC105082-1|AAI05083.1| 335|Homo sapiens 2,4-dienoyl CoA reducta... 42 0.002
BC105080-1|AAI05081.1| 335|Homo sapiens 2,4-dienoyl CoA reducta... 42 0.002
AC004612-1|AAC14671.1| 335|Homo sapiens 2,4-dienoyl-CoA reducta... 42 0.002
CR457356-1|CAG33637.1| 181|Homo sapiens MGC4172 protein. 41 0.004
AL645761-2|CAI15000.1| 147|Homo sapiens dehydrogenase/reductase... 41 0.004
AK026196-1|BAB15390.1| 181|Homo sapiens protein ( Homo sapiens ... 41 0.004
BC058883-1|AAH58883.1| 319|Homo sapiens dehydrogenase/reductase... 41 0.005
AY359046-1|AAQ89405.1| 319|Homo sapiens RDHL protein. 41 0.005
AY017349-1|AAG49422.1| 319|Homo sapiens retinol dehydrogenase p... 41 0.005
AF529288-1|AAN04010.1| 319|Homo sapiens microsomal NADP-depende... 41 0.005
AF529287-1|AAN04009.1| 319|Homo sapiens microsomal NADP-depende... 41 0.005
AF529286-1|AAN04008.1| 319|Homo sapiens microsomal NADP-depende... 41 0.005
AF343729-1|AAK37528.1| 319|Homo sapiens 3-alpha hydroxysteroid ... 41 0.005
AF295380-1|AAL37037.1| 319|Homo sapiens short-chain dehydrogena... 41 0.005
AC008177-2|AAY24306.1| 245|Homo sapiens unknown protein. 41 0.005
Z97054-7|CAI42652.1| 252|Homo sapiens hydroxysteroid (17-beta) ... 40 0.006
BC008708-1|AAH08708.1| 252|Homo sapiens hydroxysteroid (17-beta... 40 0.006
CR457145-1|CAG33426.1| 157|Homo sapiens PECR protein. 40 0.008
BC064525-1|AAH64525.1| 309|Homo sapiens epidermal retinal dehyd... 39 0.019
BC037219-1|AAH37219.2| 309|Homo sapiens epidermal retinal dehyd... 39 0.019
AB083038-1|BAB91014.1| 309|Homo sapiens retinal short chain deh... 39 0.019
CR457180-1|CAG33461.1| 318|Homo sapiens RDH11 protein. 38 0.025
BC037302-1|AAH37302.1| 318|Homo sapiens retinol dehydrogenase 1... 38 0.025
BC026274-1|AAH26274.1| 318|Homo sapiens retinol dehydrogenase 1... 38 0.025
BC011727-1|AAH11727.1| 318|Homo sapiens RDH11 protein protein. 38 0.025
BC000112-1|AAH00112.1| 318|Homo sapiens retinol dehydrogenase 1... 38 0.025
AF395068-1|AAK72049.1| 318|Homo sapiens HCV core-binding protei... 38 0.025
AF167438-1|AAF89632.1| 318|Homo sapiens androgen-regulated shor... 38 0.025
AF151840-1|AAD34077.1| 318|Homo sapiens CGI-82 protein protein. 38 0.025
AK057667-1|BAB71545.1| 231|Homo sapiens protein ( Homo sapiens ... 38 0.043
AY268353-1|AAP42287.1| 199|Homo sapiens short-chain dehydrogena... 37 0.076
AB209653-1|BAD92890.1| 166|Homo sapiens dehydrogenase/reductase... 37 0.076
X13440-1|CAA31792.1| 328|Homo sapiens protein ( Human mRNA for ... 35 0.30
U34879-1|AAD05019.1| 328|Homo sapiens 17-beta-hydroxysteroid de... 35 0.30
M84472-1|AAB16942.1| 328|Homo sapiens 17-beta-hydroxysteroid de... 35 0.30
M36263-1|AAA35600.1| 328|Homo sapiens protein ( Human placental... 35 0.30
M27138-1|AAB16941.1| 328|Homo sapiens protein ( Human estradiol... 35 0.30
BC111935-1|AAI11936.1| 328|Homo sapiens hydroxysteroid (17-beta... 35 0.30
BC104752-1|AAI04753.1| 328|Homo sapiens hydroxysteroid (17-beta... 35 0.30
BC009830-1|AAH09830.1| 336|Homo sapiens retinol dehydrogenase 1... 33 0.70
AY358511-1|AAQ88875.1| 336|Homo sapiens PAN2 protein. 33 0.70
AF237952-1|AAG12190.1| 336|Homo sapiens PAN2 protein. 33 0.70
AC079148-1|AAX93259.1| 336|Homo sapiens unknown protein. 33 0.70
DQ426886-1|ABD90542.1| 171|Homo sapiens retinol dehydrogenase 1... 33 0.93
BC150182-1|AAI50183.1| 1192|Homo sapiens reticulon 4 protein. 32 1.6
AY123250-1|AAM64254.1| 986|Homo sapiens RTN4 isoform G protein. 32 1.6
AY123249-1|AAM64253.1| 986|Homo sapiens RTN4 isoform F protein. 32 1.6
AY123248-1|AAM64252.1| 986|Homo sapiens RTN4 isoform E protein. 32 1.6
AY123247-1|AAM64251.1| 986|Homo sapiens RTN4 isoform D protein. 32 1.6
AY123246-1|AAM64250.1| 986|Homo sapiens RTN4 isoform Ab protein. 32 1.6
AY123245-1|AAM64249.1| 986|Homo sapiens RTN4 isoform Aa protein. 32 1.6
AY102285-4|AAM64244.1| 986|Homo sapiens RNT4 protein. 32 1.6
AY102285-1|AAM64243.1| 1192|Homo sapiens RTN4 protein. 32 1.6
AY102279-1|AAM64248.1| 1192|Homo sapiens RTN4 isoform A protein. 32 1.6
AJ251383-1|CAB99248.1| 1192|Homo sapiens Nogo-A protein protein. 32 1.6
AF333336-1|AAK20831.1| 986|Homo sapiens testis specific reticul... 32 1.6
AF148537-1|AAG12176.1| 1192|Homo sapiens reticulon 4a protein. 32 1.6
AC092461-1|AAX93116.1| 818|Homo sapiens unknown protein. 32 1.6
AB073359-1|BAE45717.1| 294|Homo sapiens NOGO-A protein. 32 1.6
AB040462-1|BAB18927.1| 1192|Homo sapiens RTN-xL protein. 32 1.6
AB020693-1|BAA74909.2| 1233|Homo sapiens KIAA0886 protein protein. 32 1.6
Z97054-9|CAI42651.1| 169|Homo sapiens hydroxysteroid (17-beta) ... 31 2.8
BC025724-1|AAH25724.1| 316|Homo sapiens retinol dehydrogenase 1... 31 2.8
AK054835-1|BAB70811.1| 316|Homo sapiens (ARSDR1) mRNA. protein. 31 2.8
BC112187-1|AAI12188.1| 181|Homo sapiens HSD11B1L protein protein. 31 5.0
BC093950-1|AAH93950.1| 181|Homo sapiens HSD11B1L protein protein. 31 5.0
AY313896-1|AAP83168.1| 234|Homo sapiens short-chain dehydrogena... 31 5.0
AY268351-1|AAP42285.1| 205|Homo sapiens short-chain dehydrogena... 31 5.0
AF240697-1|AAF82747.1| 172|Homo sapiens retinol dehydrogenase h... 31 5.0
>U31875-1|AAA82048.1| 280|Homo sapiens Hep27 protein protein.
Length = 280
Score = 91.9 bits (218), Expect = 2e-18
Identities = 59/198 (29%), Positives = 103/198 (52%), Gaps = 2/198 (1%)
Frame = +3
Query: 84 LSKLGAQLSLTGRNVENLQK-VSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLD 260
L++ GA + ++ R +N+ + ++K + S I + K D E+++ K ++H G +D
Sbjct: 56 LARDGAHVVISSRKQQNVDRAMAKLQGEGLSVAGIVCHVGKAEDREQLVAKALEHCGGVD 115
Query: 261 VLVNNAGIIE-TGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXG 437
LV +AG+ G+ TS +D++++ NV+S L +P++ +G
Sbjct: 116 FLVCSAGVNPLVGSTLGTSEQIWDKILSVNVKSPALLLSQLLPYMENRRGAVILVSSIAA 175
Query: 438 IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAA 617
+ YN+SK ++ TR +ALELAPK +RVNCV PG+I T+ + +E +
Sbjct: 176 YNPVVALGVYNVSKTALLGLTRTLALELAPKDIRVNCVVPGIIKTDFSKVFHGNESLWKN 235
Query: 618 FLERTKETHALGRPGKPD 671
F KE H L R G+ +
Sbjct: 236 F----KEHHQLQRIGESE 249
>BC007339-1|AAH07339.2| 271|Homo sapiens DHRS2 protein protein.
Length = 271
Score = 91.9 bits (218), Expect = 2e-18
Identities = 59/198 (29%), Positives = 103/198 (52%), Gaps = 2/198 (1%)
Frame = +3
Query: 84 LSKLGAQLSLTGRNVENLQK-VSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLD 260
L++ GA + ++ R +N+ + ++K + S I + K D E+++ K ++H G +D
Sbjct: 47 LARDGAHVVISSRKQQNVDRAMAKLQGEGLSVAGIVCHVGKAEDREQLVAKALEHCGGVD 106
Query: 261 VLVNNAGIIE-TGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXG 437
LV +AG+ G+ TS +D++++ NV+S L +P++ +G
Sbjct: 107 FLVCSAGVNPLVGSTLGTSEQIWDKILSVNVKSPALLLSQLLPYMENRRGAVILVSSIAA 166
Query: 438 IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAA 617
+ YN+SK ++ TR +ALELAPK +RVNCV PG+I T+ + +E +
Sbjct: 167 YNPVVALGVYNVSKTALLGLTRTLALELAPKDIRVNCVVPGIIKTDFSKVFHGNESLWKN 226
Query: 618 FLERTKETHALGRPGKPD 671
F KE H L R G+ +
Sbjct: 227 F----KEHHQLQRIGESE 240
>AF244132-1|AAG33703.1| 280|Homo sapiens short-chain alcohol
dehydrogenase protein.
Length = 280
Score = 91.9 bits (218), Expect = 2e-18
Identities = 59/198 (29%), Positives = 103/198 (52%), Gaps = 2/198 (1%)
Frame = +3
Query: 84 LSKLGAQLSLTGRNVENLQK-VSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLD 260
L++ GA + ++ R +N+ + ++K + S I + K D E+++ K ++H G +D
Sbjct: 56 LARDGAHVVISSRKQQNVDRAMAKLQGEGLSVAGIVCHVGKAEDREQLVAKALEHCGGVD 115
Query: 261 VLVNNAGIIE-TGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXG 437
LV +AG+ G+ TS +D++++ NV+S L +P++ +G
Sbjct: 116 FLVCSAGVNPLVGSTLGTSEQIWDKILSVNVKSPALLLSQLLPYMENRRGAVILVSSIAA 175
Query: 438 IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAA 617
+ YN+SK ++ TR +ALELAPK +RVNCV PG+I T+ + +E +
Sbjct: 176 YNPVVALGVYNVSKTALLGLTRTLALELAPKDIRVNCVVPGIIKTDFSKVFHGNESLWKN 235
Query: 618 FLERTKETHALGRPGKPD 671
F KE H L R G+ +
Sbjct: 236 F----KEHHQLQRIGESE 249
>BC006294-1|AAH06294.1| 270|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 14 protein.
Length = 270
Score = 91.5 bits (217), Expect = 3e-18
Identities = 54/163 (33%), Positives = 83/163 (50%), Gaps = 1/163 (0%)
Frame = +3
Query: 183 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTI-ENTSLAQYDRLMNTNVRSI 359
I D+T+E D++ ++ +TI +G+LD +VNNAG E TS + +L+ N+
Sbjct: 59 ILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGT 118
Query: 360 YYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVR 539
Y LT LA+P+L +S+G G + Y +K +V T+ +AL+ +P GVR
Sbjct: 119 YTLTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVR 178
Query: 540 VNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKP 668
VNC++PG I T L A + LGR G+P
Sbjct: 179 VNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQP 221
>BC006283-1|AAH06283.1| 270|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 14 protein.
Length = 270
Score = 91.5 bits (217), Expect = 3e-18
Identities = 54/163 (33%), Positives = 83/163 (50%), Gaps = 1/163 (0%)
Frame = +3
Query: 183 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTI-ENTSLAQYDRLMNTNVRSI 359
I D+T+E D++ ++ +TI +G+LD +VNNAG E TS + +L+ N+
Sbjct: 59 ILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGT 118
Query: 360 YYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVR 539
Y LT LA+P+L +S+G G + Y +K +V T+ +AL+ +P GVR
Sbjct: 119 YTLTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVR 178
Query: 540 VNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKP 668
VNC++PG I T L A + LGR G+P
Sbjct: 179 VNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQP 221
>AY358430-1|AAQ88796.1| 270|Homo sapiens ATGT502 protein.
Length = 270
Score = 91.5 bits (217), Expect = 3e-18
Identities = 54/163 (33%), Positives = 83/163 (50%), Gaps = 1/163 (0%)
Frame = +3
Query: 183 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTI-ENTSLAQYDRLMNTNVRSI 359
I D+T+E D++ ++ +TI +G+LD +VNNAG E TS + +L+ N+
Sbjct: 59 ILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGT 118
Query: 360 YYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVR 539
Y LT LA+P+L +S+G G + Y +K +V T+ +AL+ +P GVR
Sbjct: 119 YTLTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVR 178
Query: 540 VNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKP 668
VNC++PG I T L A + LGR G+P
Sbjct: 179 VNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQP 221
>AF126781-1|AAF06940.1| 270|Homo sapiens retinal short-chain
dehydrogenase/reductase retSDR3 protein.
Length = 270
Score = 91.5 bits (217), Expect = 3e-18
Identities = 54/163 (33%), Positives = 83/163 (50%), Gaps = 1/163 (0%)
Frame = +3
Query: 183 ITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTI-ENTSLAQYDRLMNTNVRSI 359
I D+T+E D++ ++ +TI +G+LD +VNNAG E TS + +L+ N+
Sbjct: 59 ILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGT 118
Query: 360 YYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVR 539
Y LT LA+P+L +S+G G + Y +K +V T+ +AL+ +P GVR
Sbjct: 119 YTLTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVR 178
Query: 540 VNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHALGRPGKP 668
VNC++PG I T L A + LGR G+P
Sbjct: 179 VNCISPGNIWTPLWEELAALMPDPRASIREGMLAQPLGRMGQP 221
>BC002786-1|AAH02786.1| 300|Homo sapiens dehydrogenase/reductase
(SDR family) member 2 protein.
Length = 300
Score = 89.0 bits (211), Expect = 1e-17
Identities = 51/169 (30%), Positives = 91/169 (53%), Gaps = 2/169 (1%)
Frame = +3
Query: 84 LSKLGAQLSLTGRNVENLQK-VSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLD 260
L++ GA + ++ R +N+ + ++K + S I + K D E+++ K ++H G +D
Sbjct: 56 LARDGAHVVISSRKQQNVDRAMAKLQGEGLSVAGIVCHVGKAEDREQLVAKALEHCGGVD 115
Query: 261 VLVNNAGIIE-TGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXG 437
LV +AG+ G+ TS +D++++ NV+S L +P++ +G
Sbjct: 116 FLVCSAGVNPLVGSTLGTSEQIWDKILSVNVKSPALLLSQLLPYMENRRGAVILVSSIAA 175
Query: 438 IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQR 584
+ YN+SK ++ TR +ALELAPK +RVNCV PG+I T+ +
Sbjct: 176 YNPVVALGVYNVSKTALLGLTRTLALELAPKDIRVNCVVPGIIKTDFSK 224
>AK222857-1|BAD96577.1| 280|Homo sapiens dehydrogenase/reductase
(SDR family) member 2 isoform 2 variant protein.
Length = 280
Score = 89.0 bits (211), Expect = 1e-17
Identities = 58/198 (29%), Positives = 103/198 (52%), Gaps = 2/198 (1%)
Frame = +3
Query: 84 LSKLGAQLSLTGRNVENLQK-VSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLD 260
L++ GA + ++ R +N+ + ++K + S I + K D E+++ K ++H G +D
Sbjct: 56 LARDGAHVVISSRKQQNVDRAMAKLQGEGLSVAGIVCHVGKAEDREQLVAKALEHCGGVD 115
Query: 261 VLVNNAGIIE-TGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXG 437
LV +AG+ G+ TS +D++++ NV+S L +P++ +G
Sbjct: 116 FLVCSAGVNPLVGSTLGTSEQIWDKILSVNVKSPAPLLSQLLPYMENRRGAVILVSSVAA 175
Query: 438 IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAA 617
+ Y++SK ++ TR +ALELAPK +RVNCV PG+I T+ + +E +
Sbjct: 176 YNPVVALGVYSVSKTALLGLTRTLALELAPKDIRVNCVVPGIIKTDFSKVFHGNESLWKN 235
Query: 618 FLERTKETHALGRPGKPD 671
F KE H L R G+ +
Sbjct: 236 F----KEHHQLQRIGESE 249
>DQ344810-1|ABD75823.1| 278|Homo sapiens NADP(H)-dependent retinol
dehydrogenase/reductase short isoform protein.
Length = 278
Score = 85.0 bits (201), Expect = 2e-16
Identities = 56/199 (28%), Positives = 103/199 (51%), Gaps = 3/199 (1%)
Frame = +3
Query: 84 LSKLGAQLSLTGRNVENL-QKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLD 260
L++ GA + ++ R +N+ Q V+ + S + K D E+++ + +G +D
Sbjct: 52 LAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCHVGKAEDRERLVATAVKLHGGID 111
Query: 261 VLVNNAGIIET-GTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXG 437
+LV+NA + G+I + + +D+ ++ NV++ +T VP + + G
Sbjct: 112 ILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALMTKAVVPEMEKRGGGSVVIVSSIA 171
Query: 438 IRS-FPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYA 614
S PG YN+SK ++ T+ +A+ELAP+ +RVNC+ PG+I T R + +E+
Sbjct: 172 AFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNCLAPGLIKTSFSRMLWMDKEKE- 230
Query: 615 AFLERTKETHALGRPGKPD 671
E KET + R G+P+
Sbjct: 231 ---ESMKETLRIRRLGEPE 246
>BC003019-1|AAH03019.1| 278|Homo sapiens dehydrogenase/reductase
(SDR family) member 4 protein.
Length = 278
Score = 85.0 bits (201), Expect = 2e-16
Identities = 56/199 (28%), Positives = 103/199 (51%), Gaps = 3/199 (1%)
Frame = +3
Query: 84 LSKLGAQLSLTGRNVENL-QKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLD 260
L++ GA + ++ R +N+ Q V+ + S + K D E+++ + +G +D
Sbjct: 52 LAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCHVGKAEDRERLVATAVKLHGGID 111
Query: 261 VLVNNAGIIET-GTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXG 437
+LV+NA + G+I + + +D+ ++ NV++ +T VP + + G
Sbjct: 112 ILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALMTKAVVPEMEKRGGGSVVIVSSIA 171
Query: 438 IRS-FPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYA 614
S PG YN+SK ++ T+ +A+ELAP+ +RVNC+ PG+I T R + +E+
Sbjct: 172 AFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNCLAPGLIKTSFSRMLWMDKEKE- 230
Query: 615 AFLERTKETHALGRPGKPD 671
E KET + R G+P+
Sbjct: 231 ---ESMKETLRIRRLGEPE 246
>AY358638-1|AAQ89001.1| 278|Homo sapiens SCAD-SRL protein.
Length = 278
Score = 85.0 bits (201), Expect = 2e-16
Identities = 56/199 (28%), Positives = 103/199 (51%), Gaps = 3/199 (1%)
Frame = +3
Query: 84 LSKLGAQLSLTGRNVENL-QKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLD 260
L++ GA + ++ R +N+ Q V+ + S + K D E+++ + +G +D
Sbjct: 52 LAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCHVGKAEDRERLVATAVKLHGGID 111
Query: 261 VLVNNAGIIET-GTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXG 437
+LV+NA + G+I + + +D+ ++ NV++ +T VP + + G
Sbjct: 112 ILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALMTKAVVPEMEKRGGGSVVIVSSIA 171
Query: 438 IRS-FPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYA 614
S PG YN+SK ++ T+ +A+ELAP+ +RVNC+ PG+I T R + +E+
Sbjct: 172 AFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNCLAPGLIKTSFSRMLWMDKEKE- 230
Query: 615 AFLERTKETHALGRPGKPD 671
E KET + R G+P+
Sbjct: 231 ---ESMKETLRIRRLGEPE 246
>AK001870-1|BAA91953.1| 278|Homo sapiens protein ( Homo sapiens
cDNA FLJ11008 fis, clone PLACE1003100, moderately
similar to HEP27 PROTEIN. ).
Length = 278
Score = 85.0 bits (201), Expect = 2e-16
Identities = 56/199 (28%), Positives = 103/199 (51%), Gaps = 3/199 (1%)
Frame = +3
Query: 84 LSKLGAQLSLTGRNVENL-QKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLD 260
L++ GA + ++ R +N+ Q V+ + S + K D E+++ + +G +D
Sbjct: 52 LAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCHVGKAEDRERLVATAVKLHGGID 111
Query: 261 VLVNNAGIIET-GTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXG 437
+LV+NA + G+I + + +D+ ++ NV++ +T VP + + G
Sbjct: 112 ILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALMTKAVVPEMEKRGGGSVVIVSSIA 171
Query: 438 IRS-FPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYA 614
S PG YN+SK ++ T+ +A+ELAP+ +RVNC+ PG+I T R + +E+
Sbjct: 172 AFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNCLAPGLIKTSFSRMLWMDKEKE- 230
Query: 615 AFLERTKETHALGRPGKPD 671
E KET + R G+P+
Sbjct: 231 ---ESMKETLRIRRLGEPE 246
>AB045131-1|BAB18775.1| 260|Homo sapiens NADPH-dependent retinol
dehydrogenase/reductase protein.
Length = 260
Score = 85.0 bits (201), Expect = 2e-16
Identities = 56/199 (28%), Positives = 103/199 (51%), Gaps = 3/199 (1%)
Frame = +3
Query: 84 LSKLGAQLSLTGRNVENL-QKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLD 260
L++ GA + ++ R +N+ Q V+ + S + K D E+++ + +G +D
Sbjct: 34 LAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCHVGKAEDRERLVATAVKLHGGID 93
Query: 261 VLVNNAGIIET-GTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXG 437
+LV+NA + G+I + + +D+ ++ NV++ +T VP + + G
Sbjct: 94 ILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALMTKAVVPEMEKRGGGSVVIVSSIA 153
Query: 438 IRS-FPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYA 614
S PG YN+SK ++ T+ +A+ELAP+ +RVNC+ PG+I T R + +E+
Sbjct: 154 AFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNCLAPGLIKTSFSRMLWMDKEKE- 212
Query: 615 AFLERTKETHALGRPGKPD 671
E KET + R G+P+
Sbjct: 213 ---ESMKETLRIRRLGEPE 228
>AF064256-1|AAQ13444.1| 278|Homo sapiens Hep27-like protein
protein.
Length = 278
Score = 84.2 bits (199), Expect = 4e-16
Identities = 56/199 (28%), Positives = 103/199 (51%), Gaps = 3/199 (1%)
Frame = +3
Query: 84 LSKLGAQLSLTGRNVENL-QKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLD 260
L++ GA + ++ R +N+ Q V+ + S + K D E+++ + +G +D
Sbjct: 52 LAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCMVGKAEDRERLVATAVKLHGGID 111
Query: 261 VLVNNAGIIET-GTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXG 437
+LV+NA + G+I + + +D+ ++ NV++ +T VP + + G
Sbjct: 112 ILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALMTKAVVPEMEKRGGGSVVIVSSIA 171
Query: 438 IRS-FPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYA 614
S PG YN+SK ++ T+ +A+ELAP+ +RVNC+ PG+I T R + +E+
Sbjct: 172 AFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNCLAPGLIKTSFSRMLWMDKEKE- 230
Query: 615 AFLERTKETHALGRPGKPD 671
E KET + R G+P+
Sbjct: 231 ---ESMKETLRIRRLGEPE 246
>AF044127-1|AAD02292.1| 260|Homo sapiens peroxisomal short-chain
alcohol dehydrogenase protein.
Length = 260
Score = 84.2 bits (199), Expect = 4e-16
Identities = 55/199 (27%), Positives = 103/199 (51%), Gaps = 3/199 (1%)
Frame = +3
Query: 84 LSKLGAQLSLTGRNVENL-QKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLD 260
L++ GA + ++ R +N+ Q V+ + S + K D E+++ + +G +D
Sbjct: 34 LAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCHVGKAEDRERLVAMAVKLHGGID 93
Query: 261 VLVNNAGIIET-GTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXG 437
+LV+NA + G++ + + +D+ ++ NV++ +T VP + + G
Sbjct: 94 ILVSNAAVNPFFGSLMDVTEEVWDKTLDINVKAPALMTKAVVPEMEKRGGGSVVIVSSIA 153
Query: 438 IRS-FPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYA 614
S PG YN+SK ++ T+ +A+ELAP+ +RVNC+ PG+I T R + +E+
Sbjct: 154 AFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNCLAPGLIKTSFSRMLWMDKEKE- 212
Query: 615 AFLERTKETHALGRPGKPD 671
E KET + R G+P+
Sbjct: 213 ---ESMKETLRIRRLGEPE 228
>BC007337-1|AAH07337.1| 339|Homo sapiens dehydrogenase/reductase
(SDR family) member 7 protein.
Length = 339
Score = 79.4 bits (187), Expect = 1e-14
Identities = 54/172 (31%), Positives = 82/172 (47%), Gaps = 7/172 (4%)
Frame = +3
Query: 84 LSKLGAQLSLTGRNVENLQKVSKDCD-----KFASTLSITADLTKESDIEKIIKKTIDHY 248
LSKLG L L+ R V L++V + C K L + DLT E K + +
Sbjct: 70 LSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLPLDLTDTGSHEAATKAVLQEF 129
Query: 249 GKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXX 425
G++D+LVNN G+ + +TSL Y +L+ N LT +PH++E K G
Sbjct: 130 GRIDILVNNGGMSQRSLCMDTSLDVYRKLIELNYLGTVSLTKCVLPHMIERKQGKIVTVN 189
Query: 426 XXXGIRSFPGVLAYNISKASVDQFTRCVALELAP-KGVRVNCVNPGVILTEL 578
GI S P + Y SK ++ F + ELA G+ V+ + PG + + +
Sbjct: 190 SILGIISVPLSIGYCASKHALRGFFNGLRTELATYPGIIVSNICPGPVQSNI 241
>BC000637-1|AAH00637.1| 339|Homo sapiens dehydrogenase/reductase
(SDR family) member 7 protein.
Length = 339
Score = 79.4 bits (187), Expect = 1e-14
Identities = 54/172 (31%), Positives = 82/172 (47%), Gaps = 7/172 (4%)
Frame = +3
Query: 84 LSKLGAQLSLTGRNVENLQKVSKDCD-----KFASTLSITADLTKESDIEKIIKKTIDHY 248
LSKLG L L+ R V L++V + C K L + DLT E K + +
Sbjct: 70 LSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLPLDLTDTGSHEAATKAVLQEF 129
Query: 249 GKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXX 425
G++D+LVNN G+ + +TSL Y +L+ N LT +PH++E K G
Sbjct: 130 GRIDILVNNGGMSQRSLCMDTSLDVYRKLIELNYLGTVSLTKCVLPHMIERKQGKIVTVN 189
Query: 426 XXXGIRSFPGVLAYNISKASVDQFTRCVALELAP-KGVRVNCVNPGVILTEL 578
GI S P + Y SK ++ F + ELA G+ V+ + PG + + +
Sbjct: 190 SILGIISVPLSIGYCASKHALRGFFNGLRTELATYPGIIVSNICPGPVQSNI 241
>AY359031-1|AAQ89390.1| 289|Homo sapiens oxidoreductase/S-2 H
protein.
Length = 289
Score = 79.4 bits (187), Expect = 1e-14
Identities = 54/172 (31%), Positives = 82/172 (47%), Gaps = 7/172 (4%)
Frame = +3
Query: 84 LSKLGAQLSLTGRNVENLQKVSKDCD-----KFASTLSITADLTKESDIEKIIKKTIDHY 248
LSKLG L L+ R V L++V + C K L + DLT E K + +
Sbjct: 20 LSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLPLDLTDTGSHEAATKAVLQEF 79
Query: 249 GKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXX 425
G++D+LVNN G+ + +TSL Y +L+ N LT +PH++E K G
Sbjct: 80 GRIDILVNNGGMSQRSLCMDTSLDVYRKLIELNYLGTVSLTKCVLPHMIERKQGKIVTVN 139
Query: 426 XXXGIRSFPGVLAYNISKASVDQFTRCVALELAP-KGVRVNCVNPGVILTEL 578
GI S P + Y SK ++ F + ELA G+ V+ + PG + + +
Sbjct: 140 SILGIISVPLSIGYCASKHALRGFFNGLRTELATYPGIIVSNICPGPVQSNI 191
>AF151844-1|AAD34081.1| 339|Homo sapiens CGI-86 protein protein.
Length = 339
Score = 79.4 bits (187), Expect = 1e-14
Identities = 54/172 (31%), Positives = 82/172 (47%), Gaps = 7/172 (4%)
Frame = +3
Query: 84 LSKLGAQLSLTGRNVENLQKVSKDCD-----KFASTLSITADLTKESDIEKIIKKTIDHY 248
LSKLG L L+ R V L++V + C K L + DLT E K + +
Sbjct: 70 LSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLPLDLTDTGSHEAATKAVLQEF 129
Query: 249 GKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXX 425
G++D+LVNN G+ + +TSL Y +L+ N LT +PH++E K G
Sbjct: 130 GRIDILVNNGGMSQRSLCMDTSLDVYRKLIELNYLGTVSLTKCVLPHMIERKQGKIVTVN 189
Query: 426 XXXGIRSFPGVLAYNISKASVDQFTRCVALELAP-KGVRVNCVNPGVILTEL 578
GI S P + Y SK ++ F + ELA G+ V+ + PG + + +
Sbjct: 190 SILGIISVPLSIGYCASKHALRGFFNGLRTELATYPGIIVSNICPGPVQSNI 241
>AF126782-1|AAF06941.1| 289|Homo sapiens retinal short-chain
dehydrogenase/reductase retSDR4 protein.
Length = 289
Score = 79.4 bits (187), Expect = 1e-14
Identities = 54/172 (31%), Positives = 82/172 (47%), Gaps = 7/172 (4%)
Frame = +3
Query: 84 LSKLGAQLSLTGRNVENLQKVSKDCD-----KFASTLSITADLTKESDIEKIIKKTIDHY 248
LSKLG L L+ R V L++V + C K L + DLT E K + +
Sbjct: 20 LSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLPLDLTDTGSHEAATKAVLQEF 79
Query: 249 GKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXX 425
G++D+LVNN G+ + +TSL Y +L+ N LT +PH++E K G
Sbjct: 80 GRIDILVNNGGMSQRSLCMDTSLDVYRKLIELNYLGTVSLTKCVLPHMIERKQGKIVTVN 139
Query: 426 XXXGIRSFPGVLAYNISKASVDQFTRCVALELAP-KGVRVNCVNPGVILTEL 578
GI S P + Y SK ++ F + ELA G+ V+ + PG + + +
Sbjct: 140 SILGIISVPLSIGYCASKHALRGFFNGLRTELATYPGIIVSNICPGPVQSNI 191
>BC002529-1|AAH02529.1| 303|Homo sapiens peroxisomal
trans-2-enoyl-CoA reductase protein.
Length = 303
Score = 78.6 bits (185), Expect = 2e-14
Identities = 44/170 (25%), Positives = 81/170 (47%), Gaps = 6/170 (3%)
Frame = +3
Query: 84 LSKLGAQLSLTGRNVENLQKVSKDCD------KFASTLSITADLTKESDIEKIIKKTIDH 245
L +LG+ + + R +E L+ + + K A + I ++ E ++ ++K T+D
Sbjct: 38 LLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQCNIRNEEEVNNLVKSTLDT 97
Query: 246 YGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXX 425
+GK++ LVNN G E+ S + ++ TN+ +Y+ ++ G
Sbjct: 98 FGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYMCKAVYSSWMKEHGGSIVNI 157
Query: 426 XXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTE 575
FP + ++A V T+ +ALE A G+R+NCV PGVI ++
Sbjct: 158 IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIRINCVAPGVIYSQ 207
>AF232009-1|AAF69798.1| 303|Homo sapiens peroxisomal trans 2-enoyl
CoA reductase protein.
Length = 303
Score = 78.6 bits (185), Expect = 2e-14
Identities = 44/170 (25%), Positives = 81/170 (47%), Gaps = 6/170 (3%)
Frame = +3
Query: 84 LSKLGAQLSLTGRNVENLQKVSKDCD------KFASTLSITADLTKESDIEKIIKKTIDH 245
L +LG+ + + R +E L+ + + K A + I ++ E ++ ++K T+D
Sbjct: 38 LLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQCNIRNEEEVNNLVKSTLDT 97
Query: 246 YGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXX 425
+GK++ LVNN G E+ S + ++ TN+ +Y+ ++ G
Sbjct: 98 FGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYMCKAVYSSWMKEHGGSIVNI 157
Query: 426 XXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTE 575
FP + ++A V T+ +ALE A G+R+NCV PGVI ++
Sbjct: 158 IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIRINCVAPGVIYSQ 207
>AF212234-1|AAK14920.1| 322|Homo sapiens HPDHase protein.
Length = 322
Score = 78.6 bits (185), Expect = 2e-14
Identities = 44/170 (25%), Positives = 81/170 (47%), Gaps = 6/170 (3%)
Frame = +3
Query: 84 LSKLGAQLSLTGRNVENLQKVSKDCD------KFASTLSITADLTKESDIEKIIKKTIDH 245
L +LG+ + + R +E L+ + + K A + I ++ E ++ ++K T+D
Sbjct: 57 LLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQCNIRNEEEVNNLVKSTLDT 116
Query: 246 YGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXX 425
+GK++ LVNN G E+ S + ++ TN+ +Y+ ++ G
Sbjct: 117 FGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYMCKAVYSSWMKEHGGSIVNI 176
Query: 426 XXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTE 575
FP + ++A V T+ +ALE A G+R+NCV PGVI ++
Sbjct: 177 IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIRINCVAPGVIYSQ 226
>AC010686-2|AAY14657.1| 303|Homo sapiens unknown protein.
Length = 303
Score = 78.6 bits (185), Expect = 2e-14
Identities = 44/170 (25%), Positives = 81/170 (47%), Gaps = 6/170 (3%)
Frame = +3
Query: 84 LSKLGAQLSLTGRNVENLQKVSKDCD------KFASTLSITADLTKESDIEKIIKKTIDH 245
L +LG+ + + R +E L+ + + K A + I ++ E ++ ++K T+D
Sbjct: 38 LLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQCNIRNEEEVNNLVKSTLDT 97
Query: 246 YGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXX 425
+GK++ LVNN G E+ S + ++ TN+ +Y+ ++ G
Sbjct: 98 FGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGTFYMCKAVYSSWMKEHGGSIVNI 157
Query: 426 XXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTE 575
FP + ++A V T+ +ALE A G+R+NCV PGVI ++
Sbjct: 158 IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIRINCVAPGVIYSQ 207
>AJ250303-1|CAB89810.1| 303|Homo sapiens peroxisomal 2-enoyl-CoA
reductase protein.
Length = 303
Score = 78.2 bits (184), Expect = 2e-14
Identities = 44/170 (25%), Positives = 81/170 (47%), Gaps = 6/170 (3%)
Frame = +3
Query: 84 LSKLGAQLSLTGRNVENLQKVSKDCD------KFASTLSITADLTKESDIEKIIKKTIDH 245
L +LG+ + + R +E L+ + + K A + I ++ E ++ ++K T+D
Sbjct: 38 LLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQCNIRNEEEVNNLVKSTLDT 97
Query: 246 YGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXX 425
+GK++ LVNN G E+ S + ++ TN+ +Y+ ++ G
Sbjct: 98 FGKINFLVNNGGGQFLSPAEHISSKGWHAVLRTNLTGSFYMCKAVYSSWMKEHGGSIVNI 157
Query: 426 XXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTE 575
FP + ++A V T+ +ALE A G+R+NCV PGVI ++
Sbjct: 158 IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIRINCVAPGVIYSQ 207
>BC095414-1|AAH95414.1| 245|Homo sapiens 3-hydroxybutyrate
dehydrogenase, type 2 protein.
Length = 245
Score = 74.9 bits (176), Expect = 2e-13
Identities = 62/211 (29%), Positives = 96/211 (45%), Gaps = 7/211 (3%)
Frame = +3
Query: 24 GKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTK 203
GKV+ ++ GA++ T N LQ++ +K+ + D+TK
Sbjct: 6 GKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQEL----EKYPGIQTRVLDVTK 61
Query: 204 ESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAV 383
+ I++ + +LDVL N AG + GT+ + +D MN NVRS+Y + +
Sbjct: 62 KKQIDQFANEV----ERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFL 117
Query: 384 PHLLESKGXXXXXXXXXGIRSFPGVL---AYNISKASVDQFTRCVALELAPKGVRVNCVN 554
P +L K S GV+ Y+ +KA+V T+ VA + +G+R NCV
Sbjct: 118 PKMLAQKSGNIINMSSVA-SSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVC 176
Query: 555 PGVILT-ELQRR---GGLSEEQYAAFLERTK 635
PG + T LQ R G EE FL+R K
Sbjct: 177 PGTVDTPSLQERIQARGNPEEARNDFLKRQK 207
>BC001953-1|AAH01953.1| 245|Homo sapiens 3-hydroxybutyrate
dehydrogenase, type 2 protein.
Length = 245
Score = 74.9 bits (176), Expect = 2e-13
Identities = 62/211 (29%), Positives = 96/211 (45%), Gaps = 7/211 (3%)
Frame = +3
Query: 24 GKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTK 203
GKV+ ++ GA++ T N LQ++ +K+ + D+TK
Sbjct: 6 GKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQEL----EKYPGIQTRVLDVTK 61
Query: 204 ESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAV 383
+ I++ + +LDVL N AG + GT+ + +D MN NVRS+Y + +
Sbjct: 62 KKQIDQFASEV----ERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFL 117
Query: 384 PHLLESKGXXXXXXXXXGIRSFPGVL---AYNISKASVDQFTRCVALELAPKGVRVNCVN 554
P +L K S GV+ Y+ +KA+V T+ VA + +G+R NCV
Sbjct: 118 PKMLAQKSGNIINMSSVA-SSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVC 176
Query: 555 PGVILT-ELQRR---GGLSEEQYAAFLERTK 635
PG + T LQ R G EE FL+R K
Sbjct: 177 PGTVDTPSLQERIQARGNPEEARNDFLKRQK 207
>AF164790-1|AAF80754.1| 245|Homo sapiens oxidoreductase UCPA
protein.
Length = 245
Score = 74.9 bits (176), Expect = 2e-13
Identities = 62/211 (29%), Positives = 96/211 (45%), Gaps = 7/211 (3%)
Frame = +3
Query: 24 GKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTK 203
GKV+ ++ GA++ T N LQ++ +K+ + D+TK
Sbjct: 6 GKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQEL----EKYPGIQTRVLDVTK 61
Query: 204 ESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAV 383
+ I++ + +LDVL N AG + GT+ + +D MN NVRS+Y + +
Sbjct: 62 KKQIDQFANEV----ERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFL 117
Query: 384 PHLLESKGXXXXXXXXXGIRSFPGVL---AYNISKASVDQFTRCVALELAPKGVRVNCVN 554
P +L K S GV+ Y+ +KA+V T+ VA + +G+R NCV
Sbjct: 118 PKMLAQKSGNIINMSSVA-SSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVC 176
Query: 555 PGVILT-ELQRR---GGLSEEQYAAFLERTK 635
PG + T LQ R G EE FL+R K
Sbjct: 177 PGTVDTPSLQERIQARGNPEEARNDFLKRQK 207
>AY358841-1|AAQ89200.1| 245|Homo sapiens GRLD6308 protein.
Length = 245
Score = 73.7 bits (173), Expect = 5e-13
Identities = 61/211 (28%), Positives = 96/211 (45%), Gaps = 7/211 (3%)
Frame = +3
Query: 24 GKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTK 203
GKV+ ++ GA++ T N LQ++ +K+ + D+TK
Sbjct: 6 GKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQEL----EKYPGIQTRVLDVTK 61
Query: 204 ESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAV 383
+ I++ + +LDVL N AG + GT+ + +D MN NVRS+Y + +
Sbjct: 62 KKQIDQFASEV----ERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFL 117
Query: 384 PHLLESKGXXXXXXXXXGIRSFPGVL---AYNISKASVDQFTRCVALELAPKGVRVNCVN 554
P +L K S GV+ Y+ +KA+V T+ +A + +G+R NCV
Sbjct: 118 PKMLAQKSGNIINMSSVA-SSVKGVVNRCVYSTTKAAVIGLTKSLAADFIQQGIRCNCVC 176
Query: 555 PGVILT-ELQRR---GGLSEEQYAAFLERTK 635
PG + T LQ R G EE FL+R K
Sbjct: 177 PGTVDTPSLQERIQARGNPEEARNDFLKRQK 207
>BC033650-1|AAH33650.1| 237|Homo sapiens carbonyl reductase 4
protein.
Length = 237
Score = 72.9 bits (171), Expect = 9e-13
Identities = 43/168 (25%), Positives = 83/168 (49%), Gaps = 1/168 (0%)
Frame = +3
Query: 84 LSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDV 263
+++ G +L++ RN+E + + D L+ + D+ KE D++ ++ H G+++
Sbjct: 22 MARKGYRLAVIARNLEGAKAAAGDLG--GDHLAFSCDVAKEHDVQNTFEELEKHLGRVNF 79
Query: 264 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXGI 440
LVN AGI G + T ++TN+ A+ +++ + G G+
Sbjct: 80 LVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTMIQQQGGSIVNVGSIVGL 139
Query: 441 RSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQR 584
+ G Y+ SK + F+R +A E+A K +RVN V PG + T++ +
Sbjct: 140 KGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFVHTDMTK 187
>BC021973-1|AAH21973.1| 237|Homo sapiens carbonyl reductase 4
protein.
Length = 237
Score = 72.9 bits (171), Expect = 9e-13
Identities = 43/168 (25%), Positives = 83/168 (49%), Gaps = 1/168 (0%)
Frame = +3
Query: 84 LSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDV 263
+++ G +L++ RN+E + + D L+ + D+ KE D++ ++ H G+++
Sbjct: 22 MARKGYRLAVIARNLEGAKAAAGDLG--GDHLAFSCDVAKEHDVQNTFEEMEKHLGRVNF 79
Query: 264 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXGI 440
LVN AGI G + T ++TN+ A+ +++ + G G+
Sbjct: 80 LVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTMIQQQGGSIVNVGSIVGL 139
Query: 441 RSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQR 584
+ G Y+ SK + F+R +A E+A K +RVN V PG + T++ +
Sbjct: 140 KGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFVHTDMTK 187
>AF151851-1|AAD34088.1| 291|Homo sapiens CGI-93 protein protein.
Length = 291
Score = 70.9 bits (166), Expect = 4e-12
Identities = 56/196 (28%), Positives = 88/196 (44%), Gaps = 9/196 (4%)
Frame = +3
Query: 96 GAQLSLTGRNVENLQKVSKDCDKFAST-------LSITADLTKESDIEKIIKKTIDHYGK 254
GA+L L GRN L+++ ++ +T +T DLT I + + +G
Sbjct: 81 GAKLVLCGRNGGALEELIRELTASHATKVQTHKPYLVTFDLTDSGAIVAAAAEILQCFGY 140
Query: 255 LDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXX 431
+D+LVNNAGI GTI +T++ R+M TN LT +P +++ + G
Sbjct: 141 VDILVNNAGISYRGTIMDTTVDVDKRVMETNYFGPVALTKALLPSMIKRRQGHIVAISSI 200
Query: 432 XGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSE-EQ 608
G S P AY SK + F C+ E+ + V ++PG I T L ++ +
Sbjct: 201 QGKMSIPFRSAYAASKHATQAFFDCLRAEMEQYEIEVTVISPGYIHTNLSVNAITADGSR 260
Query: 609 YAAFLERTKETHALGR 656
Y T + AL R
Sbjct: 261 YGVMDTTTAQAEALWR 276
>CR457124-1|CAG33405.1| 325|Homo sapiens DKFZp566O084 protein.
Length = 325
Score = 69.7 bits (163), Expect = 9e-12
Identities = 51/169 (30%), Positives = 79/169 (46%), Gaps = 8/169 (4%)
Frame = +3
Query: 96 GAQLSLTGRNVENLQKVSKDCDKFAST-------LSITADLTKESDIEKIIKKTIDHYGK 254
GA+L L GRN L+++ ++ +T +T DLT I + + +G
Sbjct: 76 GAKLVLCGRNGGALEELIRELTASHATKVQTHKPYLVTFDLTDSGAIVAAAAEILQCFGY 135
Query: 255 LDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXX 431
+D+LVNNAGI GTI +T++ R+M TN LT +P +++ + G
Sbjct: 136 VDILVNNAGISYRGTIMDTTVDVDKRVMETNYFGPVALTKALLPSMIKRRQGHIVAISSI 195
Query: 432 XGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTEL 578
G S P AY SK + F C+ E+ + V ++PG I T L
Sbjct: 196 QGKMSIPFRSAYAASKHATQAFFDCLRAEMEQYEIEVTVISPGYIHTNL 244
>BC009679-1|AAH09679.1| 325|Homo sapiens dehydrogenase/reductase
(SDR family) member 7B protein.
Length = 325
Score = 69.7 bits (163), Expect = 9e-12
Identities = 51/169 (30%), Positives = 79/169 (46%), Gaps = 8/169 (4%)
Frame = +3
Query: 96 GAQLSLTGRNVENLQKVSKDCDKFAST-------LSITADLTKESDIEKIIKKTIDHYGK 254
GA+L L GRN L+++ ++ +T +T DLT I + + +G
Sbjct: 76 GAKLVLCGRNGGALEELIRELTASHATKVQTHKPYLVTFDLTDSGAIVAAAAEILQCFGY 135
Query: 255 LDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXX 431
+D+LVNNAGI GTI +T++ R+M TN LT +P +++ + G
Sbjct: 136 VDILVNNAGISYRGTIMDTTVDVDKRVMETNYFGPVALTKALLPSMIKRRQGHIVAISSI 195
Query: 432 XGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTEL 578
G S P AY SK + F C+ E+ + V ++PG I T L
Sbjct: 196 QGKMSIPFRSAYAASKHATQAFFDCLRAEMEQYEIEVTVISPGYIHTNL 244
>BC004126-1|AAH04126.1| 325|Homo sapiens dehydrogenase/reductase
(SDR family) member 7B protein.
Length = 325
Score = 69.7 bits (163), Expect = 9e-12
Identities = 51/169 (30%), Positives = 79/169 (46%), Gaps = 8/169 (4%)
Frame = +3
Query: 96 GAQLSLTGRNVENLQKVSKDCDKFAST-------LSITADLTKESDIEKIIKKTIDHYGK 254
GA+L L GRN L+++ ++ +T +T DLT I + + +G
Sbjct: 76 GAKLVLCGRNGGALEELIRELTASHATKVQTHKPYLVTFDLTDSGAIVAAAAEILQCFGY 135
Query: 255 LDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXX 431
+D+LVNNAGI GTI +T++ R+M TN LT +P +++ + G
Sbjct: 136 VDILVNNAGISYRGTIMDTTVDVDKRVMETNYFGPVALTKALLPSMIKRRQGHIVAISSI 195
Query: 432 XGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTEL 578
G S P AY SK + F C+ E+ + V ++PG I T L
Sbjct: 196 QGKMSIPFRSAYAASKHATQAFFDCLRAEMEQYEIEVTVISPGYIHTNL 244
>AY358498-1|AAQ88862.1| 310|Homo sapiens DFIT212 protein.
Length = 310
Score = 69.7 bits (163), Expect = 9e-12
Identities = 51/169 (30%), Positives = 79/169 (46%), Gaps = 8/169 (4%)
Frame = +3
Query: 96 GAQLSLTGRNVENLQKVSKDCDKFAST-------LSITADLTKESDIEKIIKKTIDHYGK 254
GA+L L GRN L+++ ++ +T +T DLT I + + +G
Sbjct: 61 GAKLVLCGRNGGALEELIRELTASHATKVQTHKPYLVTFDLTDSGAIVAAAAEILQCFGY 120
Query: 255 LDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXX 431
+D+LVNNAGI GTI +T++ R+M TN LT +P +++ + G
Sbjct: 121 VDILVNNAGISYRGTIMDTTVDVDKRVMETNYFGPVALTKALLPSMIKRRQGHIVAISSI 180
Query: 432 XGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTEL 578
G S P AY SK + F C+ E+ + V ++PG I T L
Sbjct: 181 QGKMSIPFRSAYAASKHATQAFFDCLRAEMEQYEIEVTVISPGYIHTNL 229
>AK027337-1|BAB55045.1| 179|Homo sapiens protein ( Homo sapiens
cDNA FLJ14431 fis, clone HEMBA1006521, weakly similar to
3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE (EC
1.1.1.100). ).
Length = 179
Score = 69.3 bits (162), Expect = 1e-11
Identities = 42/160 (26%), Positives = 78/160 (48%), Gaps = 1/160 (0%)
Frame = +3
Query: 84 LSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDV 263
+++ G +L++ RN+E + + D L+ + D+ KE D++ ++ H G+++
Sbjct: 22 MARKGYRLAVIARNLEGAKAAAGDLG--GDHLAFSCDVAKEHDVQNTFEEMEKHLGRVNF 79
Query: 264 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXGI 440
LVN AGI G + T ++TN+ A+ +++ + G G+
Sbjct: 80 LVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTMIQQQGGSIVNVGSIVGL 139
Query: 441 RSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPG 560
+ G Y+ SK + F+R +A E+A K +RVN V PG
Sbjct: 140 KGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPG 179
>BC000663-1|AAH00663.2| 230|Homo sapiens dehydrogenase/reductase
(SDR family) member 4 like 2 protein.
Length = 230
Score = 62.9 bits (146), Expect = 1e-09
Identities = 39/155 (25%), Positives = 78/155 (50%), Gaps = 3/155 (1%)
Frame = +3
Query: 99 AQLSLTGRNVENL-QKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNN 275
A + ++ R +N+ Q V+ + S + K D E+++ + +G +D+LV+N
Sbjct: 55 AHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCHVGKAEDRERLVAMAVKLHGGIDILVSN 114
Query: 276 AGIIET-GTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRS-F 449
A + G++ + + +D+ ++ NV++ +T VP + + G S
Sbjct: 115 AAVNPFFGSLMDVTEEVWDKTLDINVKAPALMTKAVVPEMEKRGGGSVVIVSSIAAFSPS 174
Query: 450 PGVLAYNISKASVDQFTRCVALELAPKGVRVNCVN 554
PG YN+SK ++ +A+ELAP+ +RVNC++
Sbjct: 175 PGFSPYNVSKTALLGLNNTLAIELAPRNIRVNCLH 209
>DQ325464-1|ABC61320.1| 244|Homo sapiens NADP(H)-dependent retinol
dehydrogenase/reductase B1 isoform protein.
Length = 244
Score = 62.5 bits (145), Expect = 1e-09
Identities = 44/137 (32%), Positives = 71/137 (51%), Gaps = 6/137 (4%)
Frame = +3
Query: 279 GIIETGTIENTSLAQ-YDRLMNT----NVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIR 443
G+ TGT+ + A+ +RL+ T NV++ +T VP + + G
Sbjct: 80 GLSVTGTVCHVGKAEDRERLVATTLDINVKAPALMTKAVVPEMEKRGGGSVVIVSSIAAF 139
Query: 444 S-FPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAF 620
S PG YN+SK ++ T+ +A+ELAP+ +RVNC+ PG+I T R + +E+
Sbjct: 140 SPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNCLAPGLIKTSFSRMLWMDKEKE--- 196
Query: 621 LERTKETHALGRPGKPD 671
E KET + R G+P+
Sbjct: 197 -ESMKETLRIRRLGEPE 212
>BC015943-1|AAH15943.1| 313|Homo sapiens DHRS1 protein protein.
Length = 313
Score = 61.7 bits (143), Expect = 2e-09
Identities = 45/183 (24%), Positives = 85/183 (46%), Gaps = 9/183 (4%)
Frame = +3
Query: 84 LSKLGAQLSLTGRNVENLQKVSKDCDKFAST-LSITADLTKESDIEKIIKKTI-DHYGKL 257
L K GA + +TGR+++ L+ V+++ + + D ++ES++ + ++ + G+L
Sbjct: 27 LCKAGATVYITGRHLDTLRVVAQEAQSLGGQCVPVVCDSSQESEVRSLFEQVDREQQGRL 86
Query: 258 DVLVNNA--GIIETGTIEN-----TSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXX 416
DVLVNNA G+ N T + +D + N +R Y+ ++ ++ +
Sbjct: 87 DVLVNNAYAGVQTILNTRNKAFWETPASMWDDINNVGLRGHYFCSVYGARLMVPAGQGLI 146
Query: 417 XXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGL 596
G + + Y + KA+ D+ A EL GV + PG++ TEL +
Sbjct: 147 VVISSPGSLQYMFNVPYGVGKAACDKLAADCAHELRRHGVSCVSLWPGIVQTELLKEHMA 206
Query: 597 SEE 605
EE
Sbjct: 207 KEE 209
>BC014057-1|AAH14057.1| 313|Homo sapiens DHRS1 protein protein.
Length = 313
Score = 61.7 bits (143), Expect = 2e-09
Identities = 45/183 (24%), Positives = 85/183 (46%), Gaps = 9/183 (4%)
Frame = +3
Query: 84 LSKLGAQLSLTGRNVENLQKVSKDCDKFAST-LSITADLTKESDIEKIIKKTI-DHYGKL 257
L K GA + +TGR+++ L+ V+++ + + D ++ES++ + ++ + G+L
Sbjct: 27 LCKAGATVYITGRHLDTLRVVAQEAQSLGGQCVPVVCDSSQESEVRSLFEQVDREQQGRL 86
Query: 258 DVLVNNA--GIIETGTIEN-----TSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXX 416
DVLVNNA G+ N T + +D + N +R Y+ ++ ++ +
Sbjct: 87 DVLVNNAYAGVQTILNTRNKAFWETPASMWDDINNVGLRGHYFCSVYGARLMVPAGQGLI 146
Query: 417 XXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGL 596
G + + Y + KA+ D+ A EL GV + PG++ TEL +
Sbjct: 147 VVISSPGSLQYMFNVLYGVGKAACDKLAADCAHELRRHGVSCVSLWPGIVQTELLKEHMA 206
Query: 597 SEE 605
EE
Sbjct: 207 KEE 209
>AK058159-1|BAB71694.1| 313|Homo sapiens protein ( Homo sapiens
cDNA FLJ25430 fis, clone TST06262. ).
Length = 313
Score = 61.7 bits (143), Expect = 2e-09
Identities = 45/183 (24%), Positives = 85/183 (46%), Gaps = 9/183 (4%)
Frame = +3
Query: 84 LSKLGAQLSLTGRNVENLQKVSKDCDKFAST-LSITADLTKESDIEKIIKKTI-DHYGKL 257
L K GA + +TGR+++ L+ V+++ + + D ++ES++ + ++ + G+L
Sbjct: 27 LCKAGATVYITGRHLDTLRVVAQEAQSLGGQCVPVVCDSSQESEVRSLFEQVDREQQGRL 86
Query: 258 DVLVNNA--GIIETGTIEN-----TSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXX 416
DVLVNNA G+ N T + +D + N +R Y+ ++ ++ +
Sbjct: 87 DVLVNNAYAGVQTILNTRNKAFWETPASMWDDINNVGLRGHYFCSVYGARLMVPAGQGLI 146
Query: 417 XXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGL 596
G + + Y + KA+ D+ A EL GV + PG++ TEL +
Sbjct: 147 VVISSPGSLQYMFNVPYGVGKAACDKLAADCAHELRRHGVSCVSLWPGIVQTELLKEHMA 206
Query: 597 SEE 605
EE
Sbjct: 207 KEE 209
>AF418205-1|AAN32660.1| 313|Homo sapiens dehydrogenase/reductase
SDR family member 1 protein.
Length = 313
Score = 61.7 bits (143), Expect = 2e-09
Identities = 45/183 (24%), Positives = 85/183 (46%), Gaps = 9/183 (4%)
Frame = +3
Query: 84 LSKLGAQLSLTGRNVENLQKVSKDCDKFAST-LSITADLTKESDIEKIIKKTI-DHYGKL 257
L K GA + +TGR+++ L+ V+++ + + D ++ES++ + ++ + G+L
Sbjct: 27 LCKAGATVYITGRHLDTLRVVAQEAQSLGGQCVPVVCDSSQESEVRSLFEQVDREQQGRL 86
Query: 258 DVLVNNA--GIIETGTIEN-----TSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXX 416
DVLVNNA G+ N T + +D + N +R Y+ ++ ++ +
Sbjct: 87 DVLVNNAYAGVQTILNTRNKAFWETPASMWDDINNVGLRGHYFCSVYGARLMVPAGQGLI 146
Query: 417 XXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGL 596
G + + Y + KA+ D+ A EL GV + PG++ TEL +
Sbjct: 147 VVISSPGSLQYMFNVPYGVGKAACDKLAADCAHELRRHGVSCVSLWPGIVQTELLKEHMA 206
Query: 597 SEE 605
EE
Sbjct: 207 KEE 209
>X63657-1|CAA45197.1| 332|Homo sapiens FVT1 protein.
Length = 332
Score = 61.3 bits (142), Expect = 3e-09
Identities = 40/163 (24%), Positives = 78/163 (47%), Gaps = 7/163 (4%)
Frame = +3
Query: 90 KLGAQLSLTGRNVENLQKVSKDCDKFAST-----LSITADLTKE-SDIEKIIKKTIDHYG 251
K GA ++L RN + L + K+ + + L I+ D++++ + +E +IK+ + G
Sbjct: 54 KQGAFITLVARNEDKLLQAKKEIEMHSINDKQVVLCISVDVSQDYNQVENVIKQAQEKLG 113
Query: 252 KLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXX 428
+D+LVN AG+ +G E+ ++ ++RLM+ N Y + + + E + G
Sbjct: 114 PVDMLVNCAGMAVSGKFEDLEVSTFERLMSINYLGSVYPSRAVITTMKERRVGRIVFVSS 173
Query: 429 XXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNP 557
G G AY+ SK ++ + +E+ P V + P
Sbjct: 174 QAGQLGLFGFTAYSASKFAIRGLAEALQMEVKPYNVYITVAYP 216
>U26726-1|AAC50356.1| 405|Homo sapiens 11-beta-hydroxysteroid
dehydrogenase type 2 protein.
Length = 405
Score = 61.3 bits (142), Expect = 3e-09
Identities = 46/142 (32%), Positives = 65/142 (45%), Gaps = 3/142 (2%)
Frame = +3
Query: 192 DLTKESDIEKIIKKTIDHYGKLDV--LVNNAGIIET-GTIENTSLAQYDRLMNTNVRSIY 362
DLTK DI ++++ T H + LVNNAG E E + +A + M N
Sbjct: 138 DLTKPGDISRVLEFTKAHTTSTGLWGLVNNAGHNEVVADAELSPVATFRSCMEVNFFGAL 197
Query: 363 YLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRV 542
LT +P L S+G G +P + AY SKA+V + EL P GV+V
Sbjct: 198 ELTKGLLPLLRSSRGRIVTVGSPAGDMPYPCLGAYGTSKAAVALLMDTFSCELLPWGVKV 257
Query: 543 NCVNPGVILTELQRRGGLSEEQ 608
+ + PG TE R G E++
Sbjct: 258 SIIQPGCFKTESVRNVGQWEKR 279
>EF694683-1|ABS29267.1| 405|Homo sapiens hydroxysteroid (11-beta)
dehydrogenase 2 protein.
Length = 405
Score = 61.3 bits (142), Expect = 3e-09
Identities = 46/142 (32%), Positives = 65/142 (45%), Gaps = 3/142 (2%)
Frame = +3
Query: 192 DLTKESDIEKIIKKTIDHYGKLDV--LVNNAGIIET-GTIENTSLAQYDRLMNTNVRSIY 362
DLTK DI ++++ T H + LVNNAG E E + +A + M N
Sbjct: 138 DLTKPGDISRVLEFTKAHTTSTGLWGLVNNAGHNEVVADAELSPVATFRSCMEVNFFGAL 197
Query: 363 YLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRV 542
LT +P L S+G G +P + AY SKA+V + EL P GV+V
Sbjct: 198 ELTKGLLPLLRSSRGRIVTVGSPAGDMPYPCLGAYGTSKAAVALLMDTFSCELLPWGVKV 257
Query: 543 NCVNPGVILTELQRRGGLSEEQ 608
+ + PG TE R G E++
Sbjct: 258 SIIQPGCFKTESVRNVGQWEKR 279
>BT006782-1|AAP35428.1| 332|Homo sapiens follicular lymphoma
variant translocation 1 protein.
Length = 332
Score = 61.3 bits (142), Expect = 3e-09
Identities = 40/163 (24%), Positives = 78/163 (47%), Gaps = 7/163 (4%)
Frame = +3
Query: 90 KLGAQLSLTGRNVENLQKVSKDCDKFAST-----LSITADLTKE-SDIEKIIKKTIDHYG 251
K GA ++L RN + L + K+ + + L I+ D++++ + +E +IK+ + G
Sbjct: 54 KQGAFITLVARNEDKLLQAKKEIEMHSINDKQVVLCISVDVSQDYNQVENVIKQAQEKLG 113
Query: 252 KLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXX 428
+D+LVN AG+ +G E+ ++ ++RLM+ N Y + + + E + G
Sbjct: 114 PVDMLVNCAGMAVSGKFEDLEVSTFERLMSINYLGSVYPSRAVITTMKERRVGRIVFVSS 173
Query: 429 XXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNP 557
G G AY+ SK ++ + +E+ P V + P
Sbjct: 174 QAGQLGLFGFTAYSASKFAIRGLAEALQMEVKPYNVYITVAYP 216
>BC064536-1|AAH64536.1| 405|Homo sapiens hydroxysteroid (11-beta)
dehydrogenase 2 protein.
Length = 405
Score = 61.3 bits (142), Expect = 3e-09
Identities = 46/142 (32%), Positives = 65/142 (45%), Gaps = 3/142 (2%)
Frame = +3
Query: 192 DLTKESDIEKIIKKTIDHYGKLDV--LVNNAGIIET-GTIENTSLAQYDRLMNTNVRSIY 362
DLTK DI ++++ T H + LVNNAG E E + +A + M N
Sbjct: 138 DLTKPGDISRVLEFTKAHTTSTGLWGLVNNAGHNEVVADAELSPVATFRSCMEVNFFGAL 197
Query: 363 YLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRV 542
LT +P L S+G G +P + AY SKA+V + EL P GV+V
Sbjct: 198 ELTKGLLPLLRSSRGRIVTVGSPAGDMPYPCLGAYGTSKAAVALLMDTFSCELLPWGVKV 257
Query: 543 NCVNPGVILTELQRRGGLSEEQ 608
+ + PG TE R G E++
Sbjct: 258 SIIQPGCFKTESVRNVGQWEKR 279
>BC036780-1|AAH36780.1| 405|Homo sapiens hydroxysteroid (11-beta)
dehydrogenase 2 protein.
Length = 405
Score = 61.3 bits (142), Expect = 3e-09
Identities = 46/142 (32%), Positives = 65/142 (45%), Gaps = 3/142 (2%)
Frame = +3
Query: 192 DLTKESDIEKIIKKTIDHYGKLDV--LVNNAGIIET-GTIENTSLAQYDRLMNTNVRSIY 362
DLTK DI ++++ T H + LVNNAG E E + +A + M N
Sbjct: 138 DLTKPGDISRVLEFTKAHTTSTGLWGLVNNAGHNEVVADAELSPVATFRSCMEVNFFGAL 197
Query: 363 YLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRV 542
LT +P L S+G G +P + AY SKA+V + EL P GV+V
Sbjct: 198 ELTKGLLPLLRSSRGRIVTVGSPAGDMPYPCLGAYGTSKAAVALLMDTFSCELLPWGVKV 257
Query: 543 NCVNPGVILTELQRRGGLSEEQ 608
+ + PG TE R G E++
Sbjct: 258 SIIQPGCFKTESVRNVGQWEKR 279
>BC008797-1|AAH08797.1| 332|Homo sapiens follicular lymphoma
variant translocation 1 protein.
Length = 332
Score = 61.3 bits (142), Expect = 3e-09
Identities = 40/163 (24%), Positives = 78/163 (47%), Gaps = 7/163 (4%)
Frame = +3
Query: 90 KLGAQLSLTGRNVENLQKVSKDCDKFAST-----LSITADLTKE-SDIEKIIKKTIDHYG 251
K GA ++L RN + L + K+ + + L I+ D++++ + +E +IK+ + G
Sbjct: 54 KQGAFITLVARNEDKLLQAKKEIEMHSINDKQVVLCISVDVSQDYNQVENVIKQAQEKLG 113
Query: 252 KLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXX 428
+D+LVN AG+ +G E+ ++ ++RLM+ N Y + + + E + G
Sbjct: 114 PVDMLVNCAGMAVSGKFEDLEVSTFERLMSINYLGSVYPSRAVITTMKERRVGRIVFVSS 173
Query: 429 XXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNP 557
G G AY+ SK ++ + +E+ P V + P
Sbjct: 174 QAGQLGLFGFTAYSASKFAIRGLAEALQMEVKPYNVYITVAYP 216
>U14631-1|AAA91969.1| 405|Homo sapiens 11 beta-hydroxysteroid
dehydrogenase type II protein.
Length = 405
Score = 60.9 bits (141), Expect = 4e-09
Identities = 46/142 (32%), Positives = 65/142 (45%), Gaps = 3/142 (2%)
Frame = +3
Query: 192 DLTKESDIEKIIKKTIDHYGKLDV--LVNNAGIIET-GTIENTSLAQYDRLMNTNVRSIY 362
DLTK DI ++++ T H + LVNNAG E E + +A + M N
Sbjct: 138 DLTKPGDISRLLEFTKAHTTSTGLWGLVNNAGHNEVVADAELSPVATFRSCMEVNFFGAL 197
Query: 363 YLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRV 542
LT +P L S+G G +P + AY SKA+V + EL P GV+V
Sbjct: 198 ELTKGLLPLLRSSRGRIVTVGSPAGDMPYPCLGAYGTSKAAVALLMDTFSCELLPWGVKV 257
Query: 543 NCVNPGVILTELQRRGGLSEEQ 608
+ + PG TE R G E++
Sbjct: 258 SIIQPGCFKTESVRNVGQWEKR 279
>M93107-1|AAA58352.1| 343|Homo sapiens (R)-3-hydroxybutyrate
dehydrogenase protein.
Length = 343
Score = 60.9 bits (141), Expect = 4e-09
Identities = 34/99 (34%), Positives = 50/99 (50%)
Frame = +3
Query: 264 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIR 443
LVNNAGI G +E TSL Y ++ N+ +T +P + +KG G
Sbjct: 141 LVNNAGISTFGEVEFTSLETYKQVAEVNLWGTVRMTKSFLPLIRRAKGRVVNISSMLGRM 200
Query: 444 SFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPG 560
+ P Y I+K V+ F+ C+ E+ P GV+V+ V PG
Sbjct: 201 ANPARSPYCITKFGVEAFSDCLRYEMYPLGVKVSVVEPG 239
>BC019317-1|AAH19317.1| 343|Homo sapiens 3-hydroxybutyrate
dehydrogenase, type 1 protein.
Length = 343
Score = 60.9 bits (141), Expect = 4e-09
Identities = 34/99 (34%), Positives = 50/99 (50%)
Frame = +3
Query: 264 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIR 443
LVNNAGI G +E TSL Y ++ N+ +T +P + +KG G
Sbjct: 141 LVNNAGISTFGEVEFTSLETYKQVAEVNLWGTVRMTKSFLPLIRRAKGRVVNISSMLGRM 200
Query: 444 SFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPG 560
+ P Y I+K V+ F+ C+ E+ P GV+V+ V PG
Sbjct: 201 ANPARSPYCITKFGVEAFSDCLRYEMYPLGVKVSVVEPG 239
>BC011964-1|AAH11964.1| 343|Homo sapiens 3-hydroxybutyrate
dehydrogenase, type 1 protein.
Length = 343
Score = 60.9 bits (141), Expect = 4e-09
Identities = 34/99 (34%), Positives = 50/99 (50%)
Frame = +3
Query: 264 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIR 443
LVNNAGI G +E TSL Y ++ N+ +T +P + +KG G
Sbjct: 141 LVNNAGISTFGEVEFTSLETYKQVAEVNLWGTVRMTKSFLPLIRRAKGRVVNISSMLGRM 200
Query: 444 SFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPG 560
+ P Y I+K V+ F+ C+ E+ P GV+V+ V PG
Sbjct: 201 ANPARSPYCITKFGVEAFSDCLRYEMYPLGVKVSVVEPG 239
>BC005844-1|AAH05844.1| 343|Homo sapiens 3-hydroxybutyrate
dehydrogenase, type 1 protein.
Length = 343
Score = 60.9 bits (141), Expect = 4e-09
Identities = 34/99 (34%), Positives = 50/99 (50%)
Frame = +3
Query: 264 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIR 443
LVNNAGI G +E TSL Y ++ N+ +T +P + +KG G
Sbjct: 141 LVNNAGISTFGEVEFTSLETYKQVAEVNLWGTVRMTKSFLPLIRRAKGRVVNISSMLGRM 200
Query: 444 SFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPG 560
+ P Y I+K V+ F+ C+ E+ P GV+V+ V PG
Sbjct: 201 ANPARSPYCITKFGVEAFSDCLRYEMYPLGVKVSVVEPG 239
>U27317-1|AAB48544.1| 405|Homo sapiens 11 beta-hydroxysteroid
dehydrogenase 2 protein.
Length = 405
Score = 60.1 bits (139), Expect = 7e-09
Identities = 46/142 (32%), Positives = 64/142 (45%), Gaps = 3/142 (2%)
Frame = +3
Query: 192 DLTKESDIEKIIKKTIDHYGKLDV--LVNNAGIIET-GTIENTSLAQYDRLMNTNVRSIY 362
DLTK DI + ++ T H + LVNNAG E E + +A + M N
Sbjct: 138 DLTKPGDISRFLEFTKAHTTSTGLWGLVNNAGHNEVVADAELSPVATFRSCMEVNFFGAL 197
Query: 363 YLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRV 542
LT +P L S+G G +P + AY SKA+V + EL P GV+V
Sbjct: 198 ELTKGLLPLLRSSRGRIVTVGSPAGDMPYPCLGAYGTSKAAVALLMDTFSCELLPWGVKV 257
Query: 543 NCVNPGVILTELQRRGGLSEEQ 608
+ + PG TE R G E++
Sbjct: 258 SIIQPGCFKTESVRNVGQWEKR 279
>BC036001-1|AAH36001.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 11 protein.
Length = 300
Score = 59.7 bits (138), Expect = 9e-09
Identities = 44/167 (26%), Positives = 75/167 (44%), Gaps = 5/167 (2%)
Frame = +3
Query: 87 SKLGAQLSLTGRNVENLQKVSKDCDKFASTL-SITADLTKESDIEKIIKKTIDHYGKLDV 263
+KL ++L L N L++ + C + + + D + DI KK G + +
Sbjct: 57 AKLKSKLVLWDINKHGLEETAAKCKGLGAKVHTFVVDCSNREDIYSSAKKVKAEIGDVSI 116
Query: 264 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXGI 440
LVNNAG++ T + T Q ++ NV + ++ T +P + ++ G G
Sbjct: 117 LVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFLPAMTKNNHGHIVTVASAAGH 176
Query: 441 RSFPGVLAYNISKASVDQFTRCVALELAP---KGVRVNCVNPGVILT 572
S P +LAY SK + F + + ELA GV+ C+ P + T
Sbjct: 177 VSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGVKTTCLCPNFVNT 223
>BC021673-1|AAH21673.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 11 protein.
Length = 300
Score = 59.7 bits (138), Expect = 9e-09
Identities = 44/167 (26%), Positives = 75/167 (44%), Gaps = 5/167 (2%)
Frame = +3
Query: 87 SKLGAQLSLTGRNVENLQKVSKDCDKFASTL-SITADLTKESDIEKIIKKTIDHYGKLDV 263
+KL ++L L N L++ + C + + + D + DI KK G + +
Sbjct: 57 AKLKSKLVLWDINKHGLEETAAKCKGLGAKVHTFVVDCSNREDIYSSAKKVKAEIGDVSI 116
Query: 264 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXGI 440
LVNNAG++ T + T Q ++ NV + ++ T +P + ++ G G
Sbjct: 117 LVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFLPAMTKNNHGHIVTVASAAGH 176
Query: 441 RSFPGVLAYNISKASVDQFTRCVALELAP---KGVRVNCVNPGVILT 572
S P +LAY SK + F + + ELA GV+ C+ P + T
Sbjct: 177 VSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGVKTTCLCPNFVNT 223
>BC016367-1|AAH16367.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 11 protein.
Length = 300
Score = 59.7 bits (138), Expect = 9e-09
Identities = 44/167 (26%), Positives = 75/167 (44%), Gaps = 5/167 (2%)
Frame = +3
Query: 87 SKLGAQLSLTGRNVENLQKVSKDCDKFASTL-SITADLTKESDIEKIIKKTIDHYGKLDV 263
+KL ++L L N L++ + C + + + D + DI KK G + +
Sbjct: 57 AKLKSKLVLWDINKHGLEETAAKCKGLGAKVHTFVVDCSNREDIYSSAKKVKAEIGDVSI 116
Query: 264 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXGI 440
LVNNAG++ T + T Q ++ NV + ++ T +P + ++ G G
Sbjct: 117 LVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFLPAMTKNNHGHIVTVASAAGH 176
Query: 441 RSFPGVLAYNISKASVDQFTRCVALELAP---KGVRVNCVNPGVILT 572
S P +LAY SK + F + + ELA GV+ C+ P + T
Sbjct: 177 VSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGVKTTCLCPNFVNT 223
>BC014327-1|AAH14327.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 11 protein.
Length = 300
Score = 59.7 bits (138), Expect = 9e-09
Identities = 44/167 (26%), Positives = 75/167 (44%), Gaps = 5/167 (2%)
Frame = +3
Query: 87 SKLGAQLSLTGRNVENLQKVSKDCDKFASTL-SITADLTKESDIEKIIKKTIDHYGKLDV 263
+KL ++L L N L++ + C + + + D + DI KK G + +
Sbjct: 57 AKLKSKLVLWDINKHGLEETAAKCKGLGAKVHTFVVDCSNREDIYSSAKKVKAEIGDVSI 116
Query: 264 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXGI 440
LVNNAG++ T + T Q ++ NV + ++ T +P + ++ G G
Sbjct: 117 LVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFLPAMTKNNHGHIVTVASAAGH 176
Query: 441 RSFPGVLAYNISKASVDQFTRCVALELAP---KGVRVNCVNPGVILT 572
S P +LAY SK + F + + ELA GV+ C+ P + T
Sbjct: 177 VSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGVKTTCLCPNFVNT 223
>AY358553-1|AAQ88917.1| 300|Homo sapiens KFLL207 protein.
Length = 300
Score = 59.7 bits (138), Expect = 9e-09
Identities = 44/167 (26%), Positives = 75/167 (44%), Gaps = 5/167 (2%)
Frame = +3
Query: 87 SKLGAQLSLTGRNVENLQKVSKDCDKFASTL-SITADLTKESDIEKIIKKTIDHYGKLDV 263
+KL ++L L N L++ + C + + + D + DI KK G + +
Sbjct: 57 AKLKSKLVLWDINKHGLEETAAKCKGLGAKVHTFVVDCSNREDIYSSAKKVKAEIGDVSI 116
Query: 264 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXGI 440
LVNNAG++ T + T Q ++ NV + ++ T +P + ++ G G
Sbjct: 117 LVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFLPAMTKNNHGHIVTVASAAGH 176
Query: 441 RSFPGVLAYNISKASVDQFTRCVALELAP---KGVRVNCVNPGVILT 572
S P +LAY SK + F + + ELA GV+ C+ P + T
Sbjct: 177 VSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGVKTTCLCPNFVNT 223
>AK075348-1|BAC11560.1| 300|Homo sapiens protein ( Homo sapiens
cDNA PSEC0029 fis, clone NT2RP1000544, highly similar to
Retinal short-chain dehydrogenase/reductase 2. ).
Length = 300
Score = 59.7 bits (138), Expect = 9e-09
Identities = 44/167 (26%), Positives = 75/167 (44%), Gaps = 5/167 (2%)
Frame = +3
Query: 87 SKLGAQLSLTGRNVENLQKVSKDCDKFASTL-SITADLTKESDIEKIIKKTIDHYGKLDV 263
+KL ++L L N L++ + C + + + D + DI KK G + +
Sbjct: 57 AKLKSKLVLWDINKHGLEETAAKCKGLGAKVHTFVVDCSNREDIYSSAKKVKAEIGDVSI 116
Query: 264 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXGI 440
LVNNAG++ T + T Q ++ NV + ++ T +P + ++ G G
Sbjct: 117 LVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFLPAMTKNNHGHIVTVASAAGH 176
Query: 441 RSFPGVLAYNISKASVDQFTRCVALELAP---KGVRVNCVNPGVILT 572
S P +LAY SK + F + + ELA GV+ C+ P + T
Sbjct: 177 VSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGVKTTCLCPNFVNT 223
>AF273056-1|AAM44459.1| 300|Homo sapiens CTCL tumor antigen
HD-CL-03 protein.
Length = 300
Score = 59.7 bits (138), Expect = 9e-09
Identities = 44/167 (26%), Positives = 75/167 (44%), Gaps = 5/167 (2%)
Frame = +3
Query: 87 SKLGAQLSLTGRNVENLQKVSKDCDKFASTL-SITADLTKESDIEKIIKKTIDHYGKLDV 263
+KL ++L L N L++ + C + + + D + DI KK G + +
Sbjct: 57 AKLKSKLVLWDINKHGLEETAAKCKGLGAKVHTFVVDCSNREDIYSSAKKVKAEIGDVSI 116
Query: 264 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXGI 440
LVNNAG++ T + T Q ++ NV + ++ T +P + ++ G G
Sbjct: 117 LVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFLPAMTKNNHGHIVTVASAAGH 176
Query: 441 RSFPGVLAYNISKASVDQFTRCVALELAP---KGVRVNCVNPGVILT 572
S P +LAY SK + F + + ELA GV+ C+ P + T
Sbjct: 177 VSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGVKTTCLCPNFVNT 223
>AF139841-1|AAP97273.1| 244|Homo sapiens carbonyl reductase II
protein.
Length = 244
Score = 59.7 bits (138), Expect = 9e-09
Identities = 38/160 (23%), Positives = 68/160 (42%), Gaps = 2/160 (1%)
Frame = +3
Query: 105 LSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGI 284
L TG V + + D D + + + ++ + G +D+LVNNA +
Sbjct: 27 LHATGARVVAVSRTQADLDSLVRECPGIEPVCVDLGDWEATERALGSVGPVDLLVNNAAV 86
Query: 285 IETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES--KGXXXXXXXXXGIRSFPGV 458
+ +DR N+R++ ++ +A L+ G R+
Sbjct: 87 ALLQPFLEVTKEAFDRSFEVNLRAVIQVSQIAARGLIARGVPGAIVNVSSQCSQRAVTNH 146
Query: 459 LAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTEL 578
Y +K ++D T+ +ALEL P +RVN VNP V++T +
Sbjct: 147 SVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMTSM 186
>AF126780-1|AAF06939.1| 300|Homo sapiens retinal short-chain
dehydrogenase/reductase retSDR2 protein.
Length = 300
Score = 59.7 bits (138), Expect = 9e-09
Identities = 44/167 (26%), Positives = 75/167 (44%), Gaps = 5/167 (2%)
Frame = +3
Query: 87 SKLGAQLSLTGRNVENLQKVSKDCDKFASTL-SITADLTKESDIEKIIKKTIDHYGKLDV 263
+KL ++L L N L++ + C + + + D + DI KK G + +
Sbjct: 57 AKLKSKLVLWDINKHGLEETAAKCKGLGAKVHTFVVDCSNREDIYSSAKKVKAEIGDVSI 116
Query: 264 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXGI 440
LVNNAG++ T + T Q ++ NV + ++ T +P + ++ G G
Sbjct: 117 LVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFLPAMTKNNHGHIVTVASAAGH 176
Query: 441 RSFPGVLAYNISKASVDQFTRCVALELAP---KGVRVNCVNPGVILT 572
S P +LAY SK + F + + ELA GV+ C+ P + T
Sbjct: 177 VSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGVKTTCLCPNFVNT 223
>BC104218-1|AAI04219.1| 330|Homo sapiens hydroxysteroid
dehydrogenase like 1 protein.
Length = 330
Score = 59.3 bits (137), Expect = 1e-08
Identities = 48/171 (28%), Positives = 82/171 (47%), Gaps = 6/171 (3%)
Frame = +3
Query: 84 LSKLGAQLSLTGRNVENLQKVSKD-CDKF-ASTLSITADLTKESDIEKIIKKTIDHYGKL 257
L+ G + L RN E LQ V+KD D + T I AD + +I I++ + +
Sbjct: 87 LASRGLNIILISRNEEKLQVVAKDIADTYKVETDIIVADFSSGREIYLPIREALKDKD-V 145
Query: 258 DVLVNNAGIIETGTIENTSLAQYDRL---MNTNVRSIYYLTMLAVPHLLE-SKGXXXXXX 425
+LVNN G+ T L++ D+L +N N+ + + + +P ++E KG
Sbjct: 146 GILVNNVGVFYPYPQYFTQLSE-DKLWDIINVNIAAASLMVHVVLPGMVERKKGAIVTIS 204
Query: 426 XXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTEL 578
+ P + A++ SKA +D F+R + E A KG+ V + P + T +
Sbjct: 205 SGSCCKPTPQLAAFSASKAYLDHFSRALQYEYASKGIFVQSLIPFYVATSM 255
>AY028377-1|AAK16927.1| 309|Homo sapiens steroid dehydrogenase-like
protein protein.
Length = 309
Score = 59.3 bits (137), Expect = 1e-08
Identities = 48/171 (28%), Positives = 82/171 (47%), Gaps = 6/171 (3%)
Frame = +3
Query: 84 LSKLGAQLSLTGRNVENLQKVSKD-CDKF-ASTLSITADLTKESDIEKIIKKTIDHYGKL 257
L+ G + L RN E LQ V+KD D + T I AD + +I I++ + +
Sbjct: 66 LASRGLNIILISRNEEKLQVVAKDIADTYKVETDIIVADFSSGREIYLPIREALKDKD-V 124
Query: 258 DVLVNNAGIIETGTIENTSLAQYDRL---MNTNVRSIYYLTMLAVPHLLE-SKGXXXXXX 425
+LVNN G+ T L++ D+L +N N+ + + + +P ++E KG
Sbjct: 125 GILVNNVGVFYPYPQYFTQLSE-DKLWDIINVNIAAASLMVHVVLPGMVERKKGAIVTIS 183
Query: 426 XXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTEL 578
+ P + A++ SKA +D F+R + E A KG+ V + P + T +
Sbjct: 184 SGSCCKPTPQLAAFSASKAYLDHFSRALQYEYASKGIFVQSLIPFYVATSM 234
>AK074878-1|BAC11262.1| 330|Homo sapiens protein ( Homo sapiens
cDNA FLJ90397 fis, clone NT2RP2005878, moderately
similar to PUTATIVE STEROID DEHYDROGENASE KIK-I (EC
1.1.1.-). ).
Length = 330
Score = 59.3 bits (137), Expect = 1e-08
Identities = 48/171 (28%), Positives = 82/171 (47%), Gaps = 6/171 (3%)
Frame = +3
Query: 84 LSKLGAQLSLTGRNVENLQKVSKD-CDKF-ASTLSITADLTKESDIEKIIKKTIDHYGKL 257
L+ G + L RN E LQ V+KD D + T I AD + +I I++ + +
Sbjct: 87 LASRGLNIILISRNEEKLQVVAKDIADTYKVETDIIVADFSSGREIYLPIREALKDKD-V 145
Query: 258 DVLVNNAGIIETGTIENTSLAQYDRL---MNTNVRSIYYLTMLAVPHLLE-SKGXXXXXX 425
+LVNN G+ T L++ D+L +N N+ + + + +P ++E KG
Sbjct: 146 GILVNNVGVFYPYPQYFTQLSE-DKLWDIINVNIAAASLMVHVVLPGMVERKKGAIVTIS 204
Query: 426 XXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTEL 578
+ P + A++ SKA +D F+R + E A KG+ V + P + T +
Sbjct: 205 SGSCCKPTPQLAAFSASKAYLDHFSRALQYEYASKGIFVQSLIPFYVATSM 255
>AF237684-1|AAK15047.1| 309|Homo sapiens steroid dehydrogenase-like
protein protein.
Length = 309
Score = 59.3 bits (137), Expect = 1e-08
Identities = 48/171 (28%), Positives = 82/171 (47%), Gaps = 6/171 (3%)
Frame = +3
Query: 84 LSKLGAQLSLTGRNVENLQKVSKD-CDKF-ASTLSITADLTKESDIEKIIKKTIDHYGKL 257
L+ G + L RN E LQ V+KD D + T I AD + +I I++ + +
Sbjct: 66 LASRGLNIILISRNEEKLQVVAKDIADTYKVETDIIVADFSSGREIYLPIREALKDKD-V 124
Query: 258 DVLVNNAGIIETGTIENTSLAQYDRL---MNTNVRSIYYLTMLAVPHLLE-SKGXXXXXX 425
+LVNN G+ T L++ D+L +N N+ + + + +P ++E KG
Sbjct: 125 GILVNNVGVFYPYPQYFTQLSE-DKLWDIINVNIAAASLMVHVVLPGMVERKKGAIVTIS 183
Query: 426 XXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTEL 578
+ P + A++ SKA +D F+R + E A KG+ V + P + T +
Sbjct: 184 SGSCCKPTPQLAAFSASKAYLDHFSRALQYEYASKGIFVQSLIPFYVATSM 234
>BT006881-1|AAP35527.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 58.0 bits (134), Expect = 3e-08
Identities = 37/160 (23%), Positives = 67/160 (41%), Gaps = 2/160 (1%)
Frame = +3
Query: 105 LSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGI 284
L TG V + + D D + + + ++ + G +D+LVNNA +
Sbjct: 27 LHATGARVVAVSRTQADLDSLVRECPGIEPVCVDLGDWEATERALGSVGPVDLLVNNAAV 86
Query: 285 IETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES--KGXXXXXXXXXGIRSFPGV 458
+ +DR N+R++ ++ + L+ G R+
Sbjct: 87 ALLQPFLEVTKEAFDRSFEVNLRAVIQVSQIVARGLIARGVPGAIVNVSSQCSQRAVTNH 146
Query: 459 LAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTEL 578
Y +K ++D T+ +ALEL P +RVN VNP V++T +
Sbjct: 147 SVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMTSM 186
>BC106917-1|AAI06918.1| 330|Homo sapiens hydroxysteroid
dehydrogenase like 1 protein.
Length = 330
Score = 58.0 bits (134), Expect = 3e-08
Identities = 47/171 (27%), Positives = 82/171 (47%), Gaps = 6/171 (3%)
Frame = +3
Query: 84 LSKLGAQLSLTGRNVENLQKVSKD-CDKF-ASTLSITADLTKESDIEKIIKKTIDHYGKL 257
L+ G + L RN E LQ V+KD D + T I AD + +I I++ + +
Sbjct: 87 LASRGLNIILISRNEEKLQVVAKDIADTYKVETDIIVADFSSGREIYLPIREALKDKD-V 145
Query: 258 DVLVNNAGIIETGTIENTSLAQYDRL---MNTNVRSIYYLTMLAVPHLLE-SKGXXXXXX 425
+LVNN G+ T L++ D+L +N N+ + + + +P ++E KG
Sbjct: 146 GILVNNVGVFYPYPQYFTQLSE-DKLWDIINVNIAAASLMVHVVLPGMVERKKGAIVTIS 204
Query: 426 XXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTEL 578
+ P + A++ S+A +D F+R + E A KG+ V + P + T +
Sbjct: 205 SGSCCKPTPQLAAFSASRAYLDHFSRALQYEYASKGIFVQSLIPFYVATSM 255
>BC104219-1|AAI04220.1| 330|Homo sapiens hydroxysteroid
dehydrogenase like 1 protein.
Length = 330
Score = 58.0 bits (134), Expect = 3e-08
Identities = 47/171 (27%), Positives = 82/171 (47%), Gaps = 6/171 (3%)
Frame = +3
Query: 84 LSKLGAQLSLTGRNVENLQKVSKD-CDKF-ASTLSITADLTKESDIEKIIKKTIDHYGKL 257
L+ G + L RN E LQ V+KD D + T I AD + +I I++ + +
Sbjct: 87 LASRGLNIILISRNEEKLQVVAKDIADTYKVETDIIVADFSSGREIYLPIREALKDKD-V 145
Query: 258 DVLVNNAGIIETGTIENTSLAQYDRL---MNTNVRSIYYLTMLAVPHLLE-SKGXXXXXX 425
+LVNN G+ T L++ D+L +N N+ + + + +P ++E KG
Sbjct: 146 GILVNNVGVFYPYPQYFTQLSE-DKLWDIINVNIAAASLMVHVVLPGMVERKKGAIVTIS 204
Query: 426 XXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTEL 578
+ P + A++ S+A +D F+R + E A KG+ V + P + T +
Sbjct: 205 SGSCCKPTPQLAAFSASRAYLDHFSRALQYEYASKGIFVQSLIPFYVATSM 255
>BC003018-1|AAH03018.1| 243|Homo sapiens Unknown (protein for
IMAGE:2822726) protein.
Length = 243
Score = 58.0 bits (134), Expect = 3e-08
Identities = 37/160 (23%), Positives = 67/160 (41%), Gaps = 2/160 (1%)
Frame = +3
Query: 105 LSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGI 284
L TG V + + D D + + + ++ + G +D+LVNNA +
Sbjct: 26 LHATGARVVAVSRTQADLDSLVRECPGIEPVCVDLGDWEATERALGSVGPVDLLVNNAAV 85
Query: 285 IETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES--KGXXXXXXXXXGIRSFPGV 458
+ +DR N+R++ ++ + L+ G R+
Sbjct: 86 ALLQPFLEVTKEAFDRSFEVNLRAVIQVSQIVARGLIARGVPGAIVNVSSQCSQRAVTNH 145
Query: 459 LAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTEL 578
Y +K ++D T+ +ALEL P +RVN VNP V++T +
Sbjct: 146 SVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMTSM 185
>BC001470-1|AAH01470.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 58.0 bits (134), Expect = 3e-08
Identities = 37/160 (23%), Positives = 67/160 (41%), Gaps = 2/160 (1%)
Frame = +3
Query: 105 LSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGI 284
L TG V + + D D + + + ++ + G +D+LVNNA +
Sbjct: 27 LHATGARVVAVSRTQADLDSLVRECPGIEPVCVDLGDWEATERALGSVGPVDLLVNNAAV 86
Query: 285 IETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES--KGXXXXXXXXXGIRSFPGV 458
+ +DR N+R++ ++ + L+ G R+
Sbjct: 87 ALLQPFLEVTKEAFDRSFEVNLRAVIQVSQIVARGLIARGVPGAIVNVSSQCSQRAVTNH 146
Query: 459 LAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTEL 578
Y +K ++D T+ +ALEL P +RVN VNP V++T +
Sbjct: 147 SVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMTSM 186
>AF515625-1|AAM54026.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 58.0 bits (134), Expect = 3e-08
Identities = 37/160 (23%), Positives = 67/160 (41%), Gaps = 2/160 (1%)
Frame = +3
Query: 105 LSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGI 284
L TG V + + D D + + + ++ + G +D+LVNNA +
Sbjct: 27 LHATGARVVAVSRTQADLDSLVRECPGIEPVCVDLGDWEATERALGSVGPVDLLVNNAAV 86
Query: 285 IETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES--KGXXXXXXXXXGIRSFPGV 458
+ +DR N+R++ ++ + L+ G R+
Sbjct: 87 ALLQPFLEVTKEAFDRSFEVNLRAVIQVSQIVARGLIARGVPGAIVNVSSQCSQRAVTNH 146
Query: 459 LAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTEL 578
Y +K ++D T+ +ALEL P +RVN VNP V++T +
Sbjct: 147 SVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMTSM 186
>AF515624-1|AAO15991.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 58.0 bits (134), Expect = 3e-08
Identities = 37/160 (23%), Positives = 67/160 (41%), Gaps = 2/160 (1%)
Frame = +3
Query: 105 LSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGI 284
L TG V + + D D + + + ++ + G +D+LVNNA +
Sbjct: 27 LHATGARVVAVSRTQADLDSLVRECPGIEPVCVDLGDWEATERALGSVGPVDLLVNNAAV 86
Query: 285 IETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES--KGXXXXXXXXXGIRSFPGV 458
+ +DR N+R++ ++ + L+ G R+
Sbjct: 87 ALLQPFLEVTKEAFDRSFEVNLRAVIQVSQIVARGLIARGVPGAIVNVSSQCSQRAVTNH 146
Query: 459 LAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTEL 578
Y +K ++D T+ +ALEL P +RVN VNP V++T +
Sbjct: 147 SVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMTSM 186
>AF515623-1|AAN59786.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 58.0 bits (134), Expect = 3e-08
Identities = 37/160 (23%), Positives = 67/160 (41%), Gaps = 2/160 (1%)
Frame = +3
Query: 105 LSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGI 284
L TG V + + D D + + + ++ + G +D+LVNNA +
Sbjct: 27 LHATGARVVAVSRTQADLDSLVRECPGIEPVCVDLGDWEATERALGSVGPVDLLVNNAAV 86
Query: 285 IETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES--KGXXXXXXXXXGIRSFPGV 458
+ +DR N+R++ ++ + L+ G R+
Sbjct: 87 ALLQPFLEVTKEAFDRSFEVNLRAVIQVSQIVARGLIARGVPGAIVNVSSQCSQRAVTNH 146
Query: 459 LAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTEL 578
Y +K ++D T+ +ALEL P +RVN VNP V++T +
Sbjct: 147 SVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMTSM 186
>AF113123-1|AAF14864.1| 244|Homo sapiens carbonyl reductase
protein.
Length = 244
Score = 58.0 bits (134), Expect = 3e-08
Identities = 37/160 (23%), Positives = 67/160 (41%), Gaps = 2/160 (1%)
Frame = +3
Query: 105 LSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGI 284
L TG V + + D D + + + ++ + G +D+LVNNA +
Sbjct: 27 LHATGARVVAVSRTQADLDSLVRECPGIEPVCVDLGDWEATERALGSVGPVDLLVNNAAV 86
Query: 285 IETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES--KGXXXXXXXXXGIRSFPGV 458
+ +DR N+R++ ++ + L+ G R+
Sbjct: 87 ALLQPFLEVTKEAFDRSFEVNLRAVIQVSQIVARGLIARGVPGAIVNVSSQCSQRAVTNH 146
Query: 459 LAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTEL 578
Y +K ++D T+ +ALEL P +RVN VNP V++T +
Sbjct: 147 SVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMTSM 186
>AB013846-1|BAB64299.1| 244|Homo sapiens kidney dicarbonyl
reductase protein.
Length = 244
Score = 58.0 bits (134), Expect = 3e-08
Identities = 37/160 (23%), Positives = 67/160 (41%), Gaps = 2/160 (1%)
Frame = +3
Query: 105 LSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGI 284
L TG V + + D D + + + ++ + G +D+LVNNA +
Sbjct: 27 LHATGARVVAVSRTQADLDSLVRECPGIEPVCVDLGDWEATERALGSVGPVDLLVNNAAV 86
Query: 285 IETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES--KGXXXXXXXXXGIRSFPGV 458
+ +DR N+R++ ++ + L+ G R+
Sbjct: 87 ALLQPFLEVTKEAFDRSFEVNLRAVIQVSQIVARGLIARGVPGAIVNVSSQCSQRAVTNH 146
Query: 459 LAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTEL 578
Y +K ++D T+ +ALEL P +RVN VNP V++T +
Sbjct: 147 SVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMTSM 186
>M76665-1|AAC31757.1| 292|Homo sapiens 11-beta-hydroxysteroid
dehydrogenase protein.
Length = 292
Score = 57.6 bits (133), Expect = 4e-08
Identities = 49/169 (28%), Positives = 79/169 (46%), Gaps = 5/169 (2%)
Frame = +3
Query: 84 LSKLGAQLSLTGRNVENLQKVSKDCDKF--ASTLSITADLTKESDIEKIIKKTIDHYGKL 257
L+K+GA + +T R+ E LQKV C + AS I + + E+ + + G L
Sbjct: 54 LAKMGAHVVVTARSKETLQKVVSHCLELGAASAHYIAGTMEDMTFAEQFVAQAGKLMGGL 113
Query: 258 DVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXG 437
D+L+ N + + + + + M N S LT+ A+P L +S G G
Sbjct: 114 DMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVAALPMLKQSNGSIVVVSSLAG 173
Query: 438 IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVN---CVNPGVILTE 575
++P V AY+ SK ++D F + E + V V+ CV G+I TE
Sbjct: 174 KVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVNVSITLCV-LGLIDTE 221
>BC012593-1|AAH12593.1| 292|Homo sapiens hydroxysteroid (11-beta)
dehydrogenase 1 protein.
Length = 292
Score = 57.6 bits (133), Expect = 4e-08
Identities = 49/169 (28%), Positives = 79/169 (46%), Gaps = 5/169 (2%)
Frame = +3
Query: 84 LSKLGAQLSLTGRNVENLQKVSKDCDKF--ASTLSITADLTKESDIEKIIKKTIDHYGKL 257
L+K+GA + +T R+ E LQKV C + AS I + + E+ + + G L
Sbjct: 54 LAKMGAHVVVTARSKETLQKVVSHCLELGAASAHYIAGTMEDMTFAEQFVAQAGKLMGGL 113
Query: 258 DVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXG 437
D+L+ N + + + + + M N S LT+ A+P L +S G G
Sbjct: 114 DMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVAALPMLKQSNGSIVVVSSLAG 173
Query: 438 IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVN---CVNPGVILTE 575
++P V AY+ SK ++D F + E + V V+ CV G+I TE
Sbjct: 174 KVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVNVSITLCV-LGLIDTE 221
>AY044084-1|AAK83653.1| 292|Homo sapiens 11-beta hydroxysteroid
dehydrogenase type 1 protein.
Length = 292
Score = 57.6 bits (133), Expect = 4e-08
Identities = 49/169 (28%), Positives = 79/169 (46%), Gaps = 5/169 (2%)
Frame = +3
Query: 84 LSKLGAQLSLTGRNVENLQKVSKDCDKF--ASTLSITADLTKESDIEKIIKKTIDHYGKL 257
L+K+GA + +T R+ E LQKV C + AS I + + E+ + + G L
Sbjct: 54 LAKMGAHVVVTARSKETLQKVVSHCLELGAASAHYIAGTMEDMTFAEQFVAQAGKLMGGL 113
Query: 258 DVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXG 437
D+L+ N + + + + + M N S LT+ A+P L +S G G
Sbjct: 114 DMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVAALPMLKQSNGSIVVVSSLAG 173
Query: 438 IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVN---CVNPGVILTE 575
++P V AY+ SK ++D F + E + V V+ CV G+I TE
Sbjct: 174 KVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVNVSITLCV-LGLIDTE 221
>AL031316-4|CAI20063.1| 292|Homo sapiens hydroxysteroid (11-beta)
dehydrogenase 1 protein.
Length = 292
Score = 57.6 bits (133), Expect = 4e-08
Identities = 49/169 (28%), Positives = 79/169 (46%), Gaps = 5/169 (2%)
Frame = +3
Query: 84 LSKLGAQLSLTGRNVENLQKVSKDCDKF--ASTLSITADLTKESDIEKIIKKTIDHYGKL 257
L+K+GA + +T R+ E LQKV C + AS I + + E+ + + G L
Sbjct: 54 LAKMGAHVVVTARSKETLQKVVSHCLELGAASAHYIAGTMEDMTFAEQFVAQAGKLMGGL 113
Query: 258 DVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXG 437
D+L+ N + + + + + M N S LT+ A+P L +S G G
Sbjct: 114 DMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVAALPMLKQSNGSIVVVSSLAG 173
Query: 438 IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVN---CVNPGVILTE 575
++P V AY+ SK ++D F + E + V V+ CV G+I TE
Sbjct: 174 KVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVNVSITLCV-LGLIDTE 221
>AL022398-8|CAA18541.2| 292|Homo sapiens hydroxysteroid (11-beta)
dehydrogenase 1 protein.
Length = 292
Score = 57.6 bits (133), Expect = 4e-08
Identities = 49/169 (28%), Positives = 79/169 (46%), Gaps = 5/169 (2%)
Frame = +3
Query: 84 LSKLGAQLSLTGRNVENLQKVSKDCDKF--ASTLSITADLTKESDIEKIIKKTIDHYGKL 257
L+K+GA + +T R+ E LQKV C + AS I + + E+ + + G L
Sbjct: 54 LAKMGAHVVVTARSKETLQKVVSHCLELGAASAHYIAGTMEDMTFAEQFVAQAGKLMGGL 113
Query: 258 DVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXG 437
D+L+ N + + + + + M N S LT+ A+P L +S G G
Sbjct: 114 DMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVAALPMLKQSNGSIVVVSSLAG 173
Query: 438 IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVN---CVNPGVILTE 575
++P V AY+ SK ++D F + E + V V+ CV G+I TE
Sbjct: 174 KVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVNVSITLCV-LGLIDTE 221
>BC018084-1|AAH18084.2| 330|Homo sapiens hydroxysteroid
dehydrogenase like 1 protein.
Length = 330
Score = 57.2 bits (132), Expect = 5e-08
Identities = 47/164 (28%), Positives = 79/164 (48%), Gaps = 6/164 (3%)
Frame = +3
Query: 84 LSKLGAQLSLTGRNVENLQKVSKD-CDKF-ASTLSITADLTKESDIEKIIKKTIDHYGKL 257
L+ G + L RN E LQ V+KD D + T I AD + +I I++ + +
Sbjct: 87 LASRGLNIILISRNEEKLQVVAKDIADTYKVETDIIVADFSSGREIYLPIREALKDKD-V 145
Query: 258 DVLVNNAGIIETGTIENTSLAQYDRL---MNTNVRSIYYLTMLAVPHLLE-SKGXXXXXX 425
+LVNN G+ T L++ D+L +N N+ + + + +P ++E KG
Sbjct: 146 GILVNNVGVFYPYPQYFTQLSE-DKLWDIINVNIAAASLMVHVVLPGMVERKKGAIVTIS 204
Query: 426 XXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNP 557
+ P + A++ SKA +D F+R + E A KG+ V + P
Sbjct: 205 SGSCCKPTPQLAAFSASKAYLDHFSRALQYEYASKGIFVQSLIP 248
>BC008650-1|AAH08650.1| 300|Homo sapiens HSD17B11 protein protein.
Length = 300
Score = 57.2 bits (132), Expect = 5e-08
Identities = 43/167 (25%), Positives = 74/167 (44%), Gaps = 5/167 (2%)
Frame = +3
Query: 87 SKLGAQLSLTGRNVENLQKVSKDCDKFASTL-SITADLTKESDIEKIIKKTIDHYGKLDV 263
+KL ++L L N L++ + C + + + D + DI K G + +
Sbjct: 57 AKLKSKLVLWDINKHGLEETAAKCKGLGAKVHTFVVDCSNREDIYSSAKNCKAEIGDVSI 116
Query: 264 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXGI 440
LVNNAG++ T + T Q ++ NV + ++ T +P + ++ G G
Sbjct: 117 LVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFLPAMTKNNHGHIVTVASAAGH 176
Query: 441 RSFPGVLAYNISKASVDQFTRCVALELAP---KGVRVNCVNPGVILT 572
S P +LAY SK + F + + ELA GV+ C+ P + T
Sbjct: 177 VSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGVKTTCLCPNFVNT 223
>L76465-1|AAA89175.1| 266|Homo sapiens NAD+-dependent
15-hydroxyprostaglandin dehydrogenase protein.
Length = 266
Score = 56.8 bits (131), Expect = 7e-08
Identities = 45/170 (26%), Positives = 79/170 (46%), Gaps = 9/170 (5%)
Frame = +3
Query: 96 GAQLSLTGRNVE-NLQKVSKDCDKFA--STLSITADLTKESDIEKIIKKTIDHYGKLDVL 266
GA+++L N+E +Q + ++F TL I D+ + + +K +DH+G+LD+L
Sbjct: 29 GAKVALVDWNLEAGVQCKAALHEQFEPQKTLFIQCDVADQQQLRDTFRKVVDHFGRLDIL 88
Query: 267 VNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK----GXXXXXXXXX 434
VNNAG+ + +++ + N+ S+ T L + ++ + G
Sbjct: 89 VNNAGV--------NNEKNWEKTLQINLVSVISGTYLGLDYMSKQNGGEGGIIINMSSLA 140
Query: 435 GIRSFPGVLAYNISKASVDQFTRCVAL--ELAPKGVRVNCVNPGVILTEL 578
G+ Y SK + FTR AL L GVR+N + PG + T +
Sbjct: 141 GLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRLNAICPGFVNTAI 190
>J05594-1|AAA89174.1| 266|Homo sapiens NAD+-dependent
15-hydroxyprostaglandin dehydrogenase protein.
Length = 266
Score = 56.8 bits (131), Expect = 7e-08
Identities = 45/170 (26%), Positives = 79/170 (46%), Gaps = 9/170 (5%)
Frame = +3
Query: 96 GAQLSLTGRNVE-NLQKVSKDCDKFA--STLSITADLTKESDIEKIIKKTIDHYGKLDVL 266
GA+++L N+E +Q + ++F TL I D+ + + +K +DH+G+LD+L
Sbjct: 29 GAKVALVDWNLEAGVQCKAALHEQFEPQKTLFIQCDVADQQQLRDTFRKVVDHFGRLDIL 88
Query: 267 VNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK----GXXXXXXXXX 434
VNNAG+ + +++ + N+ S+ T L + ++ + G
Sbjct: 89 VNNAGV--------NNEKNWEKTLQINLVSVISGTYLGLDYMSKQNGGEGGIIINMSSLA 140
Query: 435 GIRSFPGVLAYNISKASVDQFTRCVAL--ELAPKGVRVNCVNPGVILTEL 578
G+ Y SK + FTR AL L GVR+N + PG + T +
Sbjct: 141 GLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRLNAICPGFVNTAI 190
>DQ903072-1|ABI75347.1| 266|Homo sapiens hydroxyprostaglandin
dehydrogenase 15-(NAD) protein.
Length = 266
Score = 56.8 bits (131), Expect = 7e-08
Identities = 45/170 (26%), Positives = 79/170 (46%), Gaps = 9/170 (5%)
Frame = +3
Query: 96 GAQLSLTGRNVE-NLQKVSKDCDKFA--STLSITADLTKESDIEKIIKKTIDHYGKLDVL 266
GA+++L N+E +Q + ++F TL I D+ + + +K +DH+G+LD+L
Sbjct: 29 GAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVADQQQLRDTFRKVVDHFGRLDIL 88
Query: 267 VNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK----GXXXXXXXXX 434
VNNAG+ + +++ + N+ S+ T L + ++ + G
Sbjct: 89 VNNAGV--------NNEKNWEKTLQINLVSVISGTYLGLDYMSKQNGGEGGIIINMSSLA 140
Query: 435 GIRSFPGVLAYNISKASVDQFTRCVAL--ELAPKGVRVNCVNPGVILTEL 578
G+ Y SK + FTR AL L GVR+N + PG + T +
Sbjct: 141 GLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRLNAICPGFVNTAI 190
>BC018986-1|AAH18986.1| 266|Homo sapiens hydroxyprostaglandin
dehydrogenase 15-(NAD) protein.
Length = 266
Score = 56.8 bits (131), Expect = 7e-08
Identities = 45/170 (26%), Positives = 79/170 (46%), Gaps = 9/170 (5%)
Frame = +3
Query: 96 GAQLSLTGRNVE-NLQKVSKDCDKFA--STLSITADLTKESDIEKIIKKTIDHYGKLDVL 266
GA+++L N+E +Q + ++F TL I D+ + + +K +DH+G+LD+L
Sbjct: 29 GAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVADQQQLRDTFRKVVDHFGRLDIL 88
Query: 267 VNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK----GXXXXXXXXX 434
VNNAG+ + +++ + N+ S+ T L + ++ + G
Sbjct: 89 VNNAGV--------NNEKNWEKTLQINLVSVISGTYLGLDYMSKQNGGEGGIIINMSSLA 140
Query: 435 GIRSFPGVLAYNISKASVDQFTRCVAL--ELAPKGVRVNCVNPGVILTEL 578
G+ Y SK + FTR AL L GVR+N + PG + T +
Sbjct: 141 GLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRLNAICPGFVNTAI 190
>X87176-1|CAA60643.1| 736|Homo sapiens 17beta-hydroxysteroid
dehydrogenase protein.
Length = 736
Score = 54.4 bits (125), Expect = 4e-07
Identities = 37/159 (23%), Positives = 68/159 (42%), Gaps = 1/159 (0%)
Frame = +3
Query: 84 LSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDV 263
++ LG G+ KV ++ + D +E EK++K +D +G++DV
Sbjct: 38 VNDLGGDFKGVGKGSLAADKVVEEIRRRGGKAVANYDSVEEG--EKVVKTALDAFGRIDV 95
Query: 264 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXGI 440
+VNNAGI+ + S +D + ++R + +T A H+ + K G GI
Sbjct: 96 VVNNAGILRDRSFARISDEDWDIIHRVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGI 155
Query: 441 RSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNP 557
G Y+ +K + +A+E + N + P
Sbjct: 156 YGNFGQANYSAAKLGLLGLANSLAIEGRKSNIHCNTIAP 194
>BC003098-1|AAH03098.1| 736|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 4 protein.
Length = 736
Score = 54.4 bits (125), Expect = 4e-07
Identities = 37/159 (23%), Positives = 68/159 (42%), Gaps = 1/159 (0%)
Frame = +3
Query: 84 LSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDV 263
++ LG G+ KV ++ + D +E EK++K +D +G++DV
Sbjct: 38 VNDLGGDFKGVGKGSLAADKVVEEIRRRGGKAVANYDSVEEG--EKVVKTALDAFGRIDV 95
Query: 264 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXGI 440
+VNNAGI+ + S +D + ++R + +T A H+ + K G GI
Sbjct: 96 VVNNAGILRDRSFARISDEDWDIIHRVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGI 155
Query: 441 RSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNP 557
G Y+ +K + +A+E + N + P
Sbjct: 156 YGNFGQANYSAAKLGLLGLANSLAIEGRKSNIHCNTIAP 194
>AF057740-1|AAD08652.1| 736|Homo sapiens 17-beta-hydroxysteroid
dehydrogenase IV protein.
Length = 736
Score = 54.4 bits (125), Expect = 4e-07
Identities = 37/159 (23%), Positives = 68/159 (42%), Gaps = 1/159 (0%)
Frame = +3
Query: 84 LSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDV 263
++ LG G+ KV ++ + D +E EK++K +D +G++DV
Sbjct: 38 VNDLGGDFKGVGKGSLAADKVVEEIRRRGGKAVANYDSVEEG--EKVVKTALDAFGRIDV 95
Query: 264 LVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXXXXXGI 440
+VNNAGI+ + S +D + ++R + +T A H+ + K G GI
Sbjct: 96 VVNNAGILRDRSFARISDEDWDIIHRVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGI 155
Query: 441 RSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNP 557
G Y+ +K + +A+E + N + P
Sbjct: 156 YGNFGQANYSAAKLGLLGLANSLAIEGRKSNIHCNTIAP 194
>BC002731-1|AAH02731.2| 260|Homo sapiens short-chain
dehydrogenase/reductase protein.
Length = 260
Score = 54.0 bits (124), Expect = 5e-07
Identities = 48/195 (24%), Positives = 86/195 (44%), Gaps = 11/195 (5%)
Frame = +3
Query: 84 LSKLGAQLSLTGRNVENLQKVSKDCDK--FASTL-SITADLTKESDIEKIIKKTIDHYGK 254
L + G ++ R V N+++++ +C + TL DL+ E DI + +
Sbjct: 31 LVQQGLKVVGCARTVGNIEELAAECKSAGYPGTLIPYRCDLSNEEDILSMFSAIRSQHSG 90
Query: 255 LDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLE---SKGXXXXXX 425
+D+ +NNAG+ T+ + S + + + N NV ++ T A + E G
Sbjct: 91 VDICINNAGLARPDTLLSGSTSGWKDMFNVNVLALSICTREAYQSMKERNVDDGHIININ 150
Query: 426 XXXGIRSFPGVLA--YNISKASVDQFTRCVALEL--APKGVRVNCVNPGVILTELQ-RRG 590
G R P + Y+ +K +V T + EL A +R C++PGV+ T+ +
Sbjct: 151 SMSGHRVLPLSVTHFYSATKYAVTALTEGLRQELREAQTHIRATCISPGVVETQFAFKLH 210
Query: 591 GLSEEQYAAFLERTK 635
E+ AA E+ K
Sbjct: 211 DKDPEKAAATYEQMK 225
>AY358712-1|AAQ89074.1| 260|Homo sapiens ARPG836 protein.
Length = 260
Score = 54.0 bits (124), Expect = 5e-07
Identities = 48/195 (24%), Positives = 86/195 (44%), Gaps = 11/195 (5%)
Frame = +3
Query: 84 LSKLGAQLSLTGRNVENLQKVSKDCDK--FASTL-SITADLTKESDIEKIIKKTIDHYGK 254
L + G ++ R V N+++++ +C + TL DL+ E DI + +
Sbjct: 31 LVQQGLKVVGCARTVGNIEELAAECKSAGYPGTLIPYRCDLSNEEDILSMFSAIRSQHSG 90
Query: 255 LDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLE---SKGXXXXXX 425
+D+ +NNAG+ T+ + S + + + N NV ++ T A + E G
Sbjct: 91 VDICINNAGLARPDTLLSGSTSGWKDMFNVNVLALSICTREAYQSMKERNVDDGHIININ 150
Query: 426 XXXGIRSFPGVLA--YNISKASVDQFTRCVALEL--APKGVRVNCVNPGVILTELQ-RRG 590
G R P + Y+ +K +V T + EL A +R C++PGV+ T+ +
Sbjct: 151 SMSGHRVLPLSVTHFYSATKYAVTALTEGLRQELREAQTHIRATCISPGVVETQFAFKLH 210
Query: 591 GLSEEQYAAFLERTK 635
E+ AA E+ K
Sbjct: 211 DKDPEKAAATYEQMK 225
>AY313894-1|AAP83166.1| 315|Homo sapiens short-chain
dehydrogenase/reductase 10e protein.
Length = 315
Score = 53.6 bits (123), Expect = 6e-07
Identities = 47/155 (30%), Positives = 67/155 (43%), Gaps = 3/155 (1%)
Frame = +3
Query: 87 SKLGAQLSLTGRNVENLQKVSKDCDKFAS--TLSITADLTKESDIEKIIKKTIDHYGKLD 260
++LG+ L LT LQKV +C K + I AD+ E +++ +D G LD
Sbjct: 50 ARLGSHLVLTAHTEALLQKVVGNCRKLGAPKVFYIAADMASPEAPESVVQFALDKLGGLD 109
Query: 261 VLV-NNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXG 437
LV N+ G GT + A LM N S LT A+P L +SKG G
Sbjct: 110 YLVLNHIGGAPAGTRARSPQATR-WLMQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLG 168
Query: 438 IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRV 542
Y+ +K ++D F + EL + V V
Sbjct: 169 RVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNV 203
>AY268352-1|AAP42286.1| 286|Homo sapiens short-chain
dehydrogenase/reductase 10b protein.
Length = 286
Score = 53.6 bits (123), Expect = 6e-07
Identities = 47/155 (30%), Positives = 67/155 (43%), Gaps = 3/155 (1%)
Frame = +3
Query: 87 SKLGAQLSLTGRNVENLQKVSKDCDKFAS--TLSITADLTKESDIEKIIKKTIDHYGKLD 260
++LG+ L LT LQKV +C K + I AD+ E +++ +D G LD
Sbjct: 50 ARLGSHLVLTAHTEALLQKVVGNCRKLGAPKVFYIAADMASPEAPESVVQFALDKLGGLD 109
Query: 261 VLV-NNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXG 437
LV N+ G GT + A LM N S LT A+P L +SKG G
Sbjct: 110 YLVLNHIGGAPAGTRARSPQATR-WLMQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLG 168
Query: 438 IRSFPGVLAYNISKASVDQFTRCVALELAPKGVRV 542
Y+ +K ++D F + EL + V V
Sbjct: 169 RVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNV 203
>L40802-1|AAC41917.1| 387|Homo sapiens 17-hydroxysteroid
dehydrogenase protein.
Length = 387
Score = 52.4 bits (120), Expect = 1e-06
Identities = 45/172 (26%), Positives = 76/172 (44%), Gaps = 6/172 (3%)
Frame = +3
Query: 81 FLSKLGAQL--SLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKT---IDH 245
+L +LG + + N +++ + C S L + D+TK I+ K +
Sbjct: 101 YLDELGFTVFAGVLNENGPGAEELRRTCSPRLSVLQM--DITKPVQIKDAYSKVAAMLQD 158
Query: 246 YGKLDVLVNNAGIIETGTI-ENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXX 422
G L ++NNAG++ T E + Y + M N +T +P L +SKG
Sbjct: 159 RG-LWAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGTVEVTKTFLPLLRKSKGRLVNV 217
Query: 423 XXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTEL 578
G + +Y SKA+V F+ + LEL+ G++V + PG LT +
Sbjct: 218 SSMGGGAPMERLASYGSSKAAVTMFSSVMRLELSKWGIKVASIQPGGFLTNI 269
>L11708-1|AAA03562.1| 387|Homo sapiens 17 beta hydroxysteroid
dehydrogenase type 2 protein.
Length = 387
Score = 52.4 bits (120), Expect = 1e-06
Identities = 45/172 (26%), Positives = 76/172 (44%), Gaps = 6/172 (3%)
Frame = +3
Query: 81 FLSKLGAQL--SLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKT---IDH 245
+L +LG + + N +++ + C S L + D+TK I+ K +
Sbjct: 101 YLDELGFTVFAGVLNENGPGAEELRRTCSPRLSVLQM--DITKPVQIKDAYSKVAAMLQD 158
Query: 246 YGKLDVLVNNAGIIETGTI-ENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXX 422
G L ++NNAG++ T E + Y + M N +T +P L +SKG
Sbjct: 159 RG-LWAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGTVEVTKTFLPLLRKSKGRLVNV 217
Query: 423 XXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTEL 578
G + +Y SKA+V F+ + LEL+ G++V + PG LT +
Sbjct: 218 SSMGGGAPMERLASYGSSKAAVTMFSSVMRLELSKWGIKVASIQPGGFLTNI 269
>BC095451-1|AAH95451.1| 418|Homo sapiens hydroxysteroid
dehydrogenase like 2 protein.
Length = 418
Score = 52.4 bits (120), Expect = 1e-06
Identities = 25/76 (32%), Positives = 38/76 (50%)
Frame = +3
Query: 177 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRS 356
L D+ E I ++K I +G +D+LVNNA I +T + D +MN N R
Sbjct: 69 LPCIVDVRDEQQISAAVEKAIKKFGGIDILVNNASAISLTNTLDTPTKRLDLMMNVNTRG 128
Query: 357 IYYLTMLAVPHLLESK 404
Y + +P+L +SK
Sbjct: 129 TYLASKACIPYLKKSK 144
>BC059170-1|AAH59170.1| 387|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 2 protein.
Length = 387
Score = 52.4 bits (120), Expect = 1e-06
Identities = 45/172 (26%), Positives = 76/172 (44%), Gaps = 6/172 (3%)
Frame = +3
Query: 81 FLSKLGAQL--SLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKT---IDH 245
+L +LG + + N +++ + C S L + D+TK I+ K +
Sbjct: 101 YLDELGFTVFAGVLNENGPGAEELRRTCSPRLSVLQM--DITKPVQIKDAYSKVAAMLQD 158
Query: 246 YGKLDVLVNNAGIIETGTI-ENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXX 422
G L ++NNAG++ T E + Y + M N +T +P L +SKG
Sbjct: 159 RG-LWAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGTVEVTKTFLPLLRKSKGRLVNV 217
Query: 423 XXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTEL 578
G + +Y SKA+V F+ + LEL+ G++V + PG LT +
Sbjct: 218 SSMGGGAPMERLASYGSSKAAVTMFSSVMRLELSKWGIKVASIQPGGFLTNI 269
>BC009581-1|AAH09581.1| 387|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 2 protein.
Length = 387
Score = 52.4 bits (120), Expect = 1e-06
Identities = 45/172 (26%), Positives = 76/172 (44%), Gaps = 6/172 (3%)
Frame = +3
Query: 81 FLSKLGAQL--SLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKT---IDH 245
+L +LG + + N +++ + C S L + D+TK I+ K +
Sbjct: 101 YLDELGFTVFAGVLNENGPGAEELRRTCSPRLSVLQM--DITKPVQIKDAYSKVAAMLQD 158
Query: 246 YGKLDVLVNNAGIIETGTI-ENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXX 422
G L ++NNAG++ T E + Y + M N +T +P L +SKG
Sbjct: 159 RG-LWAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGTVEVTKTFLPLLRKSKGRLVNV 217
Query: 423 XXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTEL 578
G + +Y SKA+V F+ + LEL+ G++V + PG LT +
Sbjct: 218 SSMGGGAPMERLASYGSSKAAVTMFSSVMRLELSKWGIKVASIQPGGFLTNI 269
>AY325910-1|AAP78485.1| 387|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 2 protein.
Length = 387
Score = 52.4 bits (120), Expect = 1e-06
Identities = 45/172 (26%), Positives = 76/172 (44%), Gaps = 6/172 (3%)
Frame = +3
Query: 81 FLSKLGAQL--SLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKT---IDH 245
+L +LG + + N +++ + C S L + D+TK I+ K +
Sbjct: 101 YLDELGFTVFAGVLNENGPGAEELRRTCSPRLSVLQM--DITKPVQIKDAYSKVAAMLQD 158
Query: 246 YGKLDVLVNNAGIIETGTI-ENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXX 422
G L ++NNAG++ T E + Y + M N +T +P L +SKG
Sbjct: 159 RG-LWAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGTVEVTKTFLPLLRKSKGRLVNV 217
Query: 423 XXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTEL 578
G + +Y SKA+V F+ + LEL+ G++V + PG LT +
Sbjct: 218 SSMGGGAPMERLASYGSSKAAVTMFSSVMRLELSKWGIKVASIQPGGFLTNI 269
>AY093428-1|AAM14670.1| 418|Homo sapiens hydroxysteroid
dehydrogenase-like protein protein.
Length = 418
Score = 52.4 bits (120), Expect = 1e-06
Identities = 25/76 (32%), Positives = 38/76 (50%)
Frame = +3
Query: 177 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRS 356
L D+ E I ++K I +G +D+LVNNA I +T + D +MN N R
Sbjct: 69 LPCIVDVRDEQQISAAVEKAIKKFGGIDILVNNASAISLTNTLDTPTKRLDLMMNVNTRG 128
Query: 357 IYYLTMLAVPHLLESK 404
Y + +P+L +SK
Sbjct: 129 TYLASKACIPYLKKSK 144
>AL162732-1|CAM17152.1| 418|Homo sapiens hydroxysteroid
dehydrogenase like 2 protein.
Length = 418
Score = 52.4 bits (120), Expect = 1e-06
Identities = 25/76 (32%), Positives = 38/76 (50%)
Frame = +3
Query: 177 LSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRS 356
L D+ E I ++K I +G +D+LVNNA I +T + D +MN N R
Sbjct: 69 LPCIVDVRDEQQISAAVEKAIKKFGGIDILVNNASAISLTNTLDTPTKRLDLMMNVNTRG 128
Query: 357 IYYLTMLAVPHLLESK 404
Y + +P+L +SK
Sbjct: 129 TYLASKACIPYLKKSK 144
>AK223001-1|BAD96721.1| 387|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 2 variant protein.
Length = 387
Score = 52.4 bits (120), Expect = 1e-06
Identities = 45/172 (26%), Positives = 76/172 (44%), Gaps = 6/172 (3%)
Frame = +3
Query: 81 FLSKLGAQL--SLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKT---IDH 245
+L +LG + + N +++ + C S L + D+TK I+ K +
Sbjct: 101 YLDELGFTVFAGVLNENGPGAEELRRTCSPRLSVLQM--DITKPVQIKDAYSKVAAMLQD 158
Query: 246 YGKLDVLVNNAGIIETGTI-ENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXX 422
G L ++NNAG++ T E + Y + M N +T +P L +SKG
Sbjct: 159 RG-LWAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGTVEVTKTFLPLLRKSKGRLVNV 217
Query: 423 XXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTEL 578
G + +Y SKA+V F+ + LEL+ G++V + PG LT +
Sbjct: 218 SSMGGGAPMERLASYGSSKAAVTMFSSVMRLELSKWGIKVASIQPGGFLTNI 269
>Z97054-8|CAI42653.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 10 protein.
Length = 261
Score = 51.2 bits (117), Expect = 3e-06
Identities = 37/143 (25%), Positives = 66/143 (46%), Gaps = 13/143 (9%)
Frame = +3
Query: 189 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENT------SLAQYDRLMNTNV 350
AD+T E D++ + +G++DV VN AGI N +L + R+++ N+
Sbjct: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122
Query: 351 RSIYYLTMLAVPHLLESK----GXXXXXXXXXGIRSFPGVL---AYNISKASVDQFTRCV 509
+ + L + +++ G + +F G + AY+ SK + T +
Sbjct: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182
Query: 510 ALELAPKGVRVNCVNPGVILTEL 578
A +LAP G+RV + PG+ T L
Sbjct: 183 ARDLAPIGIRVMTIAPGLFGTPL 205
>U96132-1|AAC51812.1| 261|Homo sapiens amyloid beta-peptide binding
protein protein.
Length = 261
Score = 51.2 bits (117), Expect = 3e-06
Identities = 37/143 (25%), Positives = 66/143 (46%), Gaps = 13/143 (9%)
Frame = +3
Query: 189 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENT------SLAQYDRLMNTNV 350
AD+T E D++ + +G++DV VN AGI N +L + R+++ N+
Sbjct: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122
Query: 351 RSIYYLTMLAVPHLLESK----GXXXXXXXXXGIRSFPGVL---AYNISKASVDQFTRCV 509
+ + L + +++ G + +F G + AY+ SK + T +
Sbjct: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182
Query: 510 ALELAPKGVRVNCVNPGVILTEL 578
A +LAP G+RV + PG+ T L
Sbjct: 183 ARDLAPIGIRVMTIAPGLFGTPL 205
>U73514-1|AAB68958.1| 261|Homo sapiens short-chain alcohol
dehydrogenase protein.
Length = 261
Score = 51.2 bits (117), Expect = 3e-06
Identities = 37/143 (25%), Positives = 66/143 (46%), Gaps = 13/143 (9%)
Frame = +3
Query: 189 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENT------SLAQYDRLMNTNV 350
AD+T E D++ + +G++DV VN AGI N +L + R+++ N+
Sbjct: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122
Query: 351 RSIYYLTMLAVPHLLESK----GXXXXXXXXXGIRSFPGVL---AYNISKASVDQFTRCV 509
+ + L + +++ G + +F G + AY+ SK + T +
Sbjct: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182
Query: 510 ALELAPKGVRVNCVNPGVILTEL 578
A +LAP G+RV + PG+ T L
Sbjct: 183 ARDLAPIGIRVMTIAPGLFGTPL 205
>CR456723-1|CAG33004.1| 261|Homo sapiens HADH2 protein.
Length = 261
Score = 51.2 bits (117), Expect = 3e-06
Identities = 37/143 (25%), Positives = 66/143 (46%), Gaps = 13/143 (9%)
Frame = +3
Query: 189 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENT------SLAQYDRLMNTNV 350
AD+T E D++ + +G++DV VN AGI N +L + R+++ N+
Sbjct: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122
Query: 351 RSIYYLTMLAVPHLLESK----GXXXXXXXXXGIRSFPGVL---AYNISKASVDQFTRCV 509
+ + L + +++ G + +F G + AY+ SK + T +
Sbjct: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182
Query: 510 ALELAPKGVRVNCVNPGVILTEL 578
A +LAP G+RV + PG+ T L
Sbjct: 183 ARDLAPIGIRVMTIAPGLFGTPL 205
>BC000372-1|AAH00372.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 10 protein.
Length = 261
Score = 51.2 bits (117), Expect = 3e-06
Identities = 37/143 (25%), Positives = 66/143 (46%), Gaps = 13/143 (9%)
Frame = +3
Query: 189 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENT------SLAQYDRLMNTNV 350
AD+T E D++ + +G++DV VN AGI N +L + R+++ N+
Sbjct: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122
Query: 351 RSIYYLTMLAVPHLLESK----GXXXXXXXXXGIRSFPGVL---AYNISKASVDQFTRCV 509
+ + L + +++ G + +F G + AY+ SK + T +
Sbjct: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182
Query: 510 ALELAPKGVRVNCVNPGVILTEL 578
A +LAP G+RV + PG+ T L
Sbjct: 183 ARDLAPIGIRVMTIAPGLFGTPL 205
>AY092415-1|AAM18189.1| 196|Homo sapiens endoplasmic
reticulum-associated amyloid beta peptide-binding
protein protein.
Length = 196
Score = 51.2 bits (117), Expect = 3e-06
Identities = 37/143 (25%), Positives = 66/143 (46%), Gaps = 13/143 (9%)
Frame = +3
Query: 189 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENT------SLAQYDRLMNTNV 350
AD+T E D++ + +G++DV VN AGI N +L + R+++ N+
Sbjct: 13 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 72
Query: 351 RSIYYLTMLAVPHLLESK----GXXXXXXXXXGIRSFPGVL---AYNISKASVDQFTRCV 509
+ + L + +++ G + +F G + AY+ SK + T +
Sbjct: 73 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 132
Query: 510 ALELAPKGVRVNCVNPGVILTEL 578
A +LAP G+RV + PG+ T L
Sbjct: 133 ARDLAPIGIRVMTIAPGLFGTPL 155
>AF069134-1|AAC39900.1| 261|Homo sapiens putative short-chain type
dehydrogenase/reductase protein.
Length = 261
Score = 51.2 bits (117), Expect = 3e-06
Identities = 37/143 (25%), Positives = 66/143 (46%), Gaps = 13/143 (9%)
Frame = +3
Query: 189 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENT------SLAQYDRLMNTNV 350
AD+T E D++ + +G++DV VN AGI N +L + R+++ N+
Sbjct: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122
Query: 351 RSIYYLTMLAVPHLLESK----GXXXXXXXXXGIRSFPGVL---AYNISKASVDQFTRCV 509
+ + L + +++ G + +F G + AY+ SK + T +
Sbjct: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182
Query: 510 ALELAPKGVRVNCVNPGVILTEL 578
A +LAP G+RV + PG+ T L
Sbjct: 183 ARDLAPIGIRVMTIAPGLFGTPL 205
>AF037438-1|AAC16419.1| 261|Homo sapiens 17beta-hydroxysteroid
dehydrogenase type 10/short chain L-3-hydroxyacyl-CoA
deh protein.
Length = 261
Score = 51.2 bits (117), Expect = 3e-06
Identities = 37/143 (25%), Positives = 66/143 (46%), Gaps = 13/143 (9%)
Frame = +3
Query: 189 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENT------SLAQYDRLMNTNV 350
AD+T E D++ + +G++DV VN AGI N +L + R+++ N+
Sbjct: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122
Query: 351 RSIYYLTMLAVPHLLESK----GXXXXXXXXXGIRSFPGVL---AYNISKASVDQFTRCV 509
+ + L + +++ G + +F G + AY+ SK + T +
Sbjct: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182
Query: 510 ALELAPKGVRVNCVNPGVILTEL 578
A +LAP G+RV + PG+ T L
Sbjct: 183 ARDLAPIGIRVMTIAPGLFGTPL 205
>AF035555-1|AAC15902.1| 261|Homo sapiens 17beta-hydroxysteroid
dehydrogenase type 10/short chain L-3-hydroxyacyl-CoA
deh protein.
Length = 261
Score = 51.2 bits (117), Expect = 3e-06
Identities = 37/143 (25%), Positives = 66/143 (46%), Gaps = 13/143 (9%)
Frame = +3
Query: 189 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENT------SLAQYDRLMNTNV 350
AD+T E D++ + +G++DV VN AGI N +L + R+++ N+
Sbjct: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122
Query: 351 RSIYYLTMLAVPHLLESK----GXXXXXXXXXGIRSFPGVL---AYNISKASVDQFTRCV 509
+ + L + +++ G + +F G + AY+ SK + T +
Sbjct: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182
Query: 510 ALELAPKGVRVNCVNPGVILTEL 578
A +LAP G+RV + PG+ T L
Sbjct: 183 ARDLAPIGIRVMTIAPGLFGTPL 205
>AF229845-1|AAF63160.1| 311|Homo sapiens photoreceptor outer
segment all-trans retinol dehydrogenase protein.
Length = 311
Score = 50.8 bits (116), Expect = 4e-06
Identities = 31/112 (27%), Positives = 54/112 (48%), Gaps = 1/112 (0%)
Frame = +3
Query: 249 GKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESK-GXXXXXX 425
G++DVLVNNAG+ G +E SLA + +TN L +P + + G
Sbjct: 82 GEVDVLVNNAGMGLVGPLEGLSLAAMQNVFDTNFFGAVRLVKAVLPGMKRRRQGHIVVIS 141
Query: 426 XXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQ 581
G++ Y SK +++ F +A++L + ++ V PG ++TE +
Sbjct: 142 SVMGLQGVIFNDVYAASKFALEGFFESLAIQLLQFNIFISLVEPGPVVTEFE 193
>CR457309-1|CAG33590.1| 173|Homo sapiens DHRS6 protein.
Length = 173
Score = 48.8 bits (111), Expect = 2e-05
Identities = 34/127 (26%), Positives = 58/127 (45%)
Frame = +3
Query: 24 GKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTK 203
GKV+ ++ GA++ T N LQ++ +K+ + D+TK
Sbjct: 6 GKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQEL----EKYPGIQTRVLDVTK 61
Query: 204 ESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAV 383
+ I++ + +LDVL N AG + GT+ + +D MN NVRS+Y + +
Sbjct: 62 KKQIDQFASEV----ERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFL 117
Query: 384 PHLLESK 404
P +L K
Sbjct: 118 PKMLAQK 124
>BC037277-1|AAH37277.1| 173|Homo sapiens BDH2 protein protein.
Length = 173
Score = 48.8 bits (111), Expect = 2e-05
Identities = 34/127 (26%), Positives = 58/127 (45%)
Frame = +3
Query: 24 GKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTK 203
GKV+ ++ GA++ T N LQ++ +K+ + D+TK
Sbjct: 6 GKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQEL----EKYPGIQTRVLDVTK 61
Query: 204 ESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAV 383
+ I++ + +LDVL N AG + GT+ + +D MN NVRS+Y + +
Sbjct: 62 KKQIDQFANEV----ERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFL 117
Query: 384 PHLLESK 404
P +L K
Sbjct: 118 PKMLAQK 124
>AY358473-1|AAQ88837.1| 331|Homo sapiens RDH13 protein.
Length = 331
Score = 48.8 bits (111), Expect = 2e-05
Identities = 45/193 (23%), Positives = 82/193 (42%), Gaps = 15/193 (7%)
Frame = +3
Query: 84 LSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITA---DLTKESDIEKIIKKTIDHYGK 254
L++ G + L R++E + +KD + A DL I + K I+ +
Sbjct: 58 LARRGGNIILACRDMEKCEAAAKDIRGETLNHHVNARHLDLASLKSIREFAAKIIEEEER 117
Query: 255 LDVLVNNAGIIETG--TIENTSLAQYD----------RLMNTNVRSIYYLTMLAVPHLLE 398
+D+L+NNAG++ T E+ Q+ L+ +++ ++ + L
Sbjct: 118 VDILINNAGVMRCPHWTTEDGFEMQFGVNHLGHFLLTNLLLDKLKASAPSRIINLSSLAH 177
Query: 399 SKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTEL 578
G R + AY SK ++ FT+ ++ L GV VN ++PGV TEL
Sbjct: 178 VAGHIDFDDLNWQTRKYNTKAAYCQSKLAIVLFTKELSRRLQGSGVTVNALHPGVARTEL 237
Query: 579 QRRGGLSEEQYAA 617
R G+ +++
Sbjct: 238 GRHTGIHGSTFSS 250
>AK023323-1|BAB14526.1| 173|Homo sapiens protein ( Homo sapiens
cDNA FLJ13261 fis, clone OVARC1000885, weakly similar to
OXIDOREDUCTASE UCPA (EC 1.-.-.-). ).
Length = 173
Score = 48.8 bits (111), Expect = 2e-05
Identities = 34/127 (26%), Positives = 58/127 (45%)
Frame = +3
Query: 24 GKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTK 203
GKV+ ++ GA++ T N LQ++ +K+ + D+TK
Sbjct: 6 GKVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQEL----EKYPGIQTRVLDVTK 61
Query: 204 ESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAV 383
+ I++ + +LDVL N AG + GT+ + +D MN NVRS+Y + +
Sbjct: 62 KKQIDQFANEV----ERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIKAFL 117
Query: 384 PHLLESK 404
P +L K
Sbjct: 118 PKMLAQK 124
>DQ088988-1|AAZ85982.1| 118|Homo sapiens DHRS4L2 isoform 2 protein.
Length = 118
Score = 47.6 bits (108), Expect = 4e-05
Identities = 29/99 (29%), Positives = 50/99 (50%), Gaps = 1/99 (1%)
Frame = +3
Query: 324 YDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRS-FPGVLAYNISKASVDQFT 500
+D+ ++ NV++ +T VP + + G S PG YN+SK ++
Sbjct: 10 WDKTLDINVKAPALMTKAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLN 69
Query: 501 RCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAA 617
+A+ELAP+ +RVNC++ + L+ L G L E + A
Sbjct: 70 NTLAIELAPRNIRVNCLH--LDLSRLASAGWLGEPEDCA 106
>AK075392-1|BAC11591.1| 331|Homo sapiens protein ( Homo sapiens
cDNA PSEC0082 fis, clone NT2RP2004966, highly similar to
Retinol dehydrogenase 13 (EC 1.1.1.-). ).
Length = 331
Score = 47.6 bits (108), Expect = 4e-05
Identities = 45/193 (23%), Positives = 81/193 (41%), Gaps = 15/193 (7%)
Frame = +3
Query: 84 LSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITA---DLTKESDIEKIIKKTIDHYGK 254
L++ G + L R++E + +KD + A DL I K I+ +
Sbjct: 58 LARRGGNIILACRDMEKCEAAAKDIRGETLNHHVNARHLDLASLKSIRVFAAKIIEEEER 117
Query: 255 LDVLVNNAGIIETG--TIENTSLAQYD----------RLMNTNVRSIYYLTMLAVPHLLE 398
+D+L+NNAG++ T E+ Q+ L+ +++ ++ + L
Sbjct: 118 VDILINNAGVMRCPHWTTEDGFEMQFGVNHLGHFLLTNLLLDKLKASAPSRIINLSSLAH 177
Query: 399 SKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTEL 578
G R + AY SK ++ FT+ ++ L GV VN ++PGV TEL
Sbjct: 178 VAGHIDFDDLNWQTRKYNTKAAYCQSKLAIVLFTKELSRRLQGSGVTVNALHPGVARTEL 237
Query: 579 QRRGGLSEEQYAA 617
R G+ +++
Sbjct: 238 GRHTGIHGSTFSS 250
>U43559-1|AAC50725.1| 318|Homo sapiens 11-cis retinol dehydrogenase
protein.
Length = 318
Score = 47.2 bits (107), Expect = 5e-05
Identities = 44/180 (24%), Positives = 76/180 (42%), Gaps = 1/180 (0%)
Frame = +3
Query: 111 LTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIE 290
LT E+LQ+V+ + +TL D K ++ + G L LVNNAG+
Sbjct: 60 LTPSGAEDLQRVASS--RLHTTLLDITDPQSVQQAAKWVEMHVKEAG-LFGLVNNAGVAG 116
Query: 291 T-GTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAY 467
G + + R++N N +T+ +P L +++G G + G Y
Sbjct: 117 IIGPTPWLTRDDFQRVLNVNTMGPIGVTLALLPLLQQARGRVINITSVLGRLAANGG-GY 175
Query: 468 NISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHA 647
+SK ++ F+ + ++A G+RV+ V PG T + L + A + T A
Sbjct: 176 CVSKFGLEAFSDSLRRDVAHFGIRVSIVEPGFFRTPVTNLESLEKTLQACWARLPPATQA 235
>BC028298-1|AAH28298.1| 318|Homo sapiens retinol dehydrogenase 5
(11-cis/9-cis) protein.
Length = 318
Score = 47.2 bits (107), Expect = 5e-05
Identities = 44/180 (24%), Positives = 76/180 (42%), Gaps = 1/180 (0%)
Frame = +3
Query: 111 LTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIE 290
LT E+LQ+V+ + +TL D K ++ + G L LVNNAG+
Sbjct: 60 LTPSGAEDLQRVASS--RLHTTLLDITDPQSVQQAAKWVEMHVKEAG-LFGLVNNAGVAG 116
Query: 291 T-GTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAY 467
G + + R++N N +T+ +P L +++G G + G Y
Sbjct: 117 IIGPTPWLTRDDFQRVLNVNTMGPIGVTLALLPLLQQARGRVINITSVLGRLAANGG-GY 175
Query: 468 NISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHA 647
+SK ++ F+ + ++A G+RV+ V PG T + L + A + T A
Sbjct: 176 CVSKFGLEAFSDSLRRDVAHFGIRVSIVEPGFFRTPVTNLESLEKTLQACWARLPPATQA 235
>AF037062-1|AAC09250.1| 318|Homo sapiens retinol dehydrogenase
protein.
Length = 318
Score = 47.2 bits (107), Expect = 5e-05
Identities = 44/180 (24%), Positives = 76/180 (42%), Gaps = 1/180 (0%)
Frame = +3
Query: 111 LTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIE 290
LT E+LQ+V+ + +TL D K ++ + G L LVNNAG+
Sbjct: 60 LTPSGAEDLQRVASS--RLHTTLLDITDPQSVQQAAKWVEMHVKEAG-LFGLVNNAGVAG 116
Query: 291 T-GTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAY 467
G + + R++N N +T+ +P L +++G G + G Y
Sbjct: 117 IIGPTPWLTRDDFQRVLNVNTMGPIGVTLALLPLLQQARGRVINITSVLGRLAANGG-GY 175
Query: 468 NISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHA 647
+SK ++ F+ + ++A G+RV+ V PG T + L + A + T A
Sbjct: 176 CVSKFGLEAFSDSLRRDVAHFGIRVSIVEPGFFRTPVTNLESLEKTLQACWARLPPATQA 235
>BC101553-1|AAI01554.1| 313|Homo sapiens orphan short-chain
dehydrogenase / reductase protein.
Length = 313
Score = 46.8 bits (106), Expect = 7e-05
Identities = 43/174 (24%), Positives = 77/174 (44%), Gaps = 3/174 (1%)
Frame = +3
Query: 129 ENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGK--LDVLVNNAGI-IETGT 299
E QK+ +D T + D+TK I+ + D G+ L LVNNAG+ + +G
Sbjct: 60 EGSQKLQRDTSYRLQTTLL--DVTKSESIKAAAQWVRDKVGEQGLWALVNNAGVGLPSGP 117
Query: 300 IENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISK 479
E + + +++N N+ + +T+ +P + ++G G + G Y +SK
Sbjct: 118 NEWLTKDDFVKVINVNLVGLIEVTLHMLPMVKRARGRVVNMSSSGGRVAVIGG-GYCVSK 176
Query: 480 ASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKET 641
V+ F+ + EL GV+V + PG T + + L + +ET
Sbjct: 177 FGVEAFSDSIRRELYYFGVKVCIIEPGNYRTAILGKENLESRMRKLWERLPQET 230
>BC101551-1|AAI01552.1| 313|Homo sapiens orphan short-chain
dehydrogenase / reductase protein.
Length = 313
Score = 46.8 bits (106), Expect = 7e-05
Identities = 43/174 (24%), Positives = 77/174 (44%), Gaps = 3/174 (1%)
Frame = +3
Query: 129 ENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGK--LDVLVNNAGI-IETGT 299
E QK+ +D T + D+TK I+ + D G+ L LVNNAG+ + +G
Sbjct: 60 EGSQKLQRDTSYRLQTTLL--DVTKSESIKAAAQWVRDKVGEQGLWALVNNAGVGLPSGP 117
Query: 300 IENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISK 479
E + + +++N N+ + +T+ +P + ++G G + G Y +SK
Sbjct: 118 NEWLTKDDFVKVINVNLVGLIEVTLHMLPMVKRARGRVVNMSSSGGRVAVIGG-GYCVSK 176
Query: 480 ASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKET 641
V+ F+ + EL GV+V + PG T + + L + +ET
Sbjct: 177 FGVEAFSDSIRRELYYFGVKVCIIEPGNYRTAILGKENLESRMRKLWERLPQET 230
>AY044434-1|AAK95856.1| 313|Homo sapiens retinol dehydrogenase
similar protein protein.
Length = 313
Score = 46.8 bits (106), Expect = 7e-05
Identities = 43/174 (24%), Positives = 77/174 (44%), Gaps = 3/174 (1%)
Frame = +3
Query: 129 ENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGK--LDVLVNNAGI-IETGT 299
E QK+ +D T + D+TK I+ + D G+ L LVNNAG+ + +G
Sbjct: 60 EGSQKLQRDTSYRLQTTLL--DVTKSESIKAAAQWVRDKVGEQGLWALVNNAGVGLPSGP 117
Query: 300 IENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISK 479
E + + +++N N+ + +T+ +P + ++G G + G Y +SK
Sbjct: 118 NEWLTKDDFVKVINVNLVGLIEVTLHMLPMVKRARGRVVNMSSSGGRVAVIGG-GYCVSK 176
Query: 480 ASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKET 641
V+ F+ + EL GV+V + PG T + + L + +ET
Sbjct: 177 FGVEAFSDSIRRELYYFGVKVCIIEPGNYRTAILGKENLESRMRKLWERLPQET 230
>BC020710-1|AAH20710.1| 317|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 6 homolog (mouse) protein.
Length = 317
Score = 46.0 bits (104), Expect = 1e-04
Identities = 35/134 (26%), Positives = 63/134 (47%), Gaps = 3/134 (2%)
Frame = +3
Query: 180 SITADLTKESDIEKIIKKTIDHYGKLDV--LVNNAGIIETGTI-ENTSLAQYDRLMNTNV 350
++T D+TK I + +H G + LVNNAGI+ T+ E + ++ N+
Sbjct: 79 TVTLDVTKMESIAAATQWVKEHVGDRGLWGLVNNAGILTPITLCEWLNTEDSMNMLKVNL 138
Query: 351 RSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPK 530
+ +T+ +P + ++G G +F V Y +SK V+ F+ + E+
Sbjct: 139 IGVIQVTLSMLPLVRRARGRIVNVSSILGRVAF-FVGGYCVSKYGVEAFSDILRREIQHF 197
Query: 531 GVRVNCVNPGVILT 572
GV+++ V PG T
Sbjct: 198 GVKISIVEPGYFRT 211
>AF223225-1|AAF81017.1| 317|Homo sapiens 3-hydroxysteroid epimerase
protein.
Length = 317
Score = 46.0 bits (104), Expect = 1e-04
Identities = 35/134 (26%), Positives = 63/134 (47%), Gaps = 3/134 (2%)
Frame = +3
Query: 180 SITADLTKESDIEKIIKKTIDHYGKLDV--LVNNAGIIETGTI-ENTSLAQYDRLMNTNV 350
++T D+TK I + +H G + LVNNAGI+ T+ E + ++ N+
Sbjct: 79 TVTLDVTKMESIAAATQWVKEHVGDRGLWGLVNNAGILTPITLCEWLNTEDSMNMLKVNL 138
Query: 351 RSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPK 530
+ +T+ +P + ++G G +F V Y +SK V+ F+ + E+
Sbjct: 139 IGVIQVTLSMLPLVRRARGRIVNVSSILGRVAF-FVGGYCVSKYGVEAFSDILRREIQHF 197
Query: 531 GVRVNCVNPGVILT 572
GV+++ V PG T
Sbjct: 198 GVKISIVEPGYFRT 211
>AF016509-1|AAB67236.1| 317|Homo sapiens oxidoreductase protein.
Length = 317
Score = 46.0 bits (104), Expect = 1e-04
Identities = 35/134 (26%), Positives = 63/134 (47%), Gaps = 3/134 (2%)
Frame = +3
Query: 180 SITADLTKESDIEKIIKKTIDHYGKLDV--LVNNAGIIETGTI-ENTSLAQYDRLMNTNV 350
++T D+TK I + +H G + LVNNAGI+ T+ E + ++ N+
Sbjct: 79 TVTLDVTKMESIAAATQWVKEHVGDRGLWGLVNNAGILTPITLCEWLNTEDSMNMLKVNL 138
Query: 351 RSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPK 530
+ +T+ +P + ++G G +F V Y +SK V+ F+ + E+
Sbjct: 139 IGVIQVTLSMLPLVRRARGRIVNVSSILGRVAF-FVGGYCVSKYGVEAFSDILRREIQHF 197
Query: 531 GVRVNCVNPGVILT 572
GV+++ V PG T
Sbjct: 198 GVKISIVEPGYFRT 211
>X82460-1|CAA57843.1| 178|Homo sapiens 15-hydroxy prostaglandin
dehydrogenase protein.
Length = 178
Score = 45.6 bits (103), Expect = 2e-04
Identities = 25/75 (33%), Positives = 42/75 (56%), Gaps = 3/75 (4%)
Frame = +3
Query: 96 GAQLSLTGRNVE-NLQKVSKDCDKFA--STLSITADLTKESDIEKIIKKTIDHYGKLDVL 266
GA+++L N+E +Q + ++F TL I D+ + + +K +DH+G+LD+L
Sbjct: 29 GAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVADQQQLRDTFRKVVDHFGRLDIL 88
Query: 267 VNNAGIIETGTIENT 311
VNNAG+ E T
Sbjct: 89 VNNAGVNNKKNWEKT 103
>U89281-1|AAB88252.1| 317|Homo sapiens oxidative 3 alpha
hydroxysteroid dehydrogenase protein.
Length = 317
Score = 45.6 bits (103), Expect = 2e-04
Identities = 35/134 (26%), Positives = 62/134 (46%), Gaps = 3/134 (2%)
Frame = +3
Query: 180 SITADLTKESDIEKIIKKTIDHYG--KLDVLVNNAGIIETGTI-ENTSLAQYDRLMNTNV 350
++T D+TK I + +H G +L LVNNAGI+ T+ E + ++ N+
Sbjct: 79 TVTLDVTKMESIAAATQWVKEHVGDRRLWGLVNNAGILTPITLCEWLNTEDSMNMLKVNL 138
Query: 351 RSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPK 530
+ +T+ +P + ++G G F Y +SK V+ F+ + E+
Sbjct: 139 IGVIQVTLSMLPLVRRARGKNCQCLQHSGKSCFL-CRGYCVSKYGVEAFSDILRREIQHF 197
Query: 531 GVRVNCVNPGVILT 572
GV+++ V PG T
Sbjct: 198 GVKISIVEPGYFRT 211
>U63296-1|AAB53034.1| 143|Homo sapiens 15-hydroxyprostaglandin
dehydrogenase protein.
Length = 143
Score = 45.6 bits (103), Expect = 2e-04
Identities = 25/75 (33%), Positives = 42/75 (56%), Gaps = 3/75 (4%)
Frame = +3
Query: 96 GAQLSLTGRNVE-NLQKVSKDCDKFA--STLSITADLTKESDIEKIIKKTIDHYGKLDVL 266
GA+++L N+E +Q + ++F TL I D+ + + +K +DH+G+LD+L
Sbjct: 29 GAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVADQQQLRDTFRKVVDHFGRLDIL 88
Query: 267 VNNAGIIETGTIENT 311
VNNAG+ E T
Sbjct: 89 VNNAGVNNEKNWEKT 103
>BT007239-1|AAP35903.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 44.4 bits (100), Expect = 4e-04
Identities = 31/111 (27%), Positives = 52/111 (46%), Gaps = 2/111 (1%)
Frame = +3
Query: 261 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES--KGXXXXXXXXX 434
V+V+ AGI + + + S +D+++ N++ + +T A L+ + +G
Sbjct: 99 VVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIV 158
Query: 435 GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRR 587
G G Y SKA V T+ A EL G+R N V PG I T + ++
Sbjct: 159 GKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPMTQK 209
>BC008185-1|AAH08185.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 44.4 bits (100), Expect = 4e-04
Identities = 31/111 (27%), Positives = 52/111 (46%), Gaps = 2/111 (1%)
Frame = +3
Query: 261 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES--KGXXXXXXXXX 434
V+V+ AGI + + + S +D+++ N++ + +T A L+ + +G
Sbjct: 99 VVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIV 158
Query: 435 GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRR 587
G G Y SKA V T+ A EL G+R N V PG I T + ++
Sbjct: 159 GKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPMTQK 209
>AL844527-12|CAI41840.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 44.4 bits (100), Expect = 4e-04
Identities = 31/111 (27%), Positives = 52/111 (46%), Gaps = 2/111 (1%)
Frame = +3
Query: 261 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES--KGXXXXXXXXX 434
V+V+ AGI + + + S +D+++ N++ + +T A L+ + +G
Sbjct: 99 VVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIV 158
Query: 435 GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRR 587
G G Y SKA V T+ A EL G+R N V PG I T + ++
Sbjct: 159 GKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPMTQK 209
>AL713971-6|CAI17657.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 44.4 bits (100), Expect = 4e-04
Identities = 31/111 (27%), Positives = 52/111 (46%), Gaps = 2/111 (1%)
Frame = +3
Query: 261 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES--KGXXXXXXXXX 434
V+V+ AGI + + + S +D+++ N++ + +T A L+ + +G
Sbjct: 99 VVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIV 158
Query: 435 GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRR 587
G G Y SKA V T+ A EL G+R N V PG I T + ++
Sbjct: 159 GKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPMTQK 209
>AL662824-24|CAI17616.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 44.4 bits (100), Expect = 4e-04
Identities = 31/111 (27%), Positives = 52/111 (46%), Gaps = 2/111 (1%)
Frame = +3
Query: 261 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES--KGXXXXXXXXX 434
V+V+ AGI + + + S +D+++ N++ + +T A L+ + +G
Sbjct: 99 VVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIV 158
Query: 435 GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRR 587
G G Y SKA V T+ A EL G+R N V PG I T + ++
Sbjct: 159 GKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPMTQK 209
>AL645940-10|CAI18068.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 44.4 bits (100), Expect = 4e-04
Identities = 31/111 (27%), Positives = 52/111 (46%), Gaps = 2/111 (1%)
Frame = +3
Query: 261 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES--KGXXXXXXXXX 434
V+V+ AGI + + + S +D+++ N++ + +T A L+ + +G
Sbjct: 99 VVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIV 158
Query: 435 GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRR 587
G G Y SKA V T+ A EL G+R N V PG I T + ++
Sbjct: 159 GKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPMTQK 209
>AL031228-10|CAC38444.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 44.4 bits (100), Expect = 4e-04
Identities = 31/111 (27%), Positives = 52/111 (46%), Gaps = 2/111 (1%)
Frame = +3
Query: 261 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES--KGXXXXXXXXX 434
V+V+ AGI + + + S +D+++ N++ + +T A L+ + +G
Sbjct: 99 VVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIV 158
Query: 435 GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRR 587
G G Y SKA V T+ A EL G+R N V PG I T + ++
Sbjct: 159 GKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIATPMTQK 209
>BC067131-1|AAH67131.1| 341|Homo sapiens retinol dehydrogenase 10
(all-trans) protein.
Length = 341
Score = 44.0 bits (99), Expect = 5e-04
Identities = 37/137 (27%), Positives = 62/137 (45%), Gaps = 4/137 (2%)
Frame = +3
Query: 186 TADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYY 365
T D+ K ++ ++ G++ VLVNNAG++ + +R M N + ++
Sbjct: 116 TCDVGKRENVYLTAERVRKEVGEVSVLVNNAGVVSGHHLLECPDELIERTMMVNCHAHFW 175
Query: 366 LTMLAVPHLLE-SKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALEL--APK-G 533
T +P +LE + G G+ S GV Y SK V F ++ EL A K G
Sbjct: 176 TTKAFLPTMLEINHGHIVTVASSLGLFSTAGVEDYCASKFGVVGFHESLSHELKAAEKDG 235
Query: 534 VRVNCVNPGVILTELQR 584
++ V P ++ T + R
Sbjct: 236 IKTTLVCPYLVDTGMFR 252
>AY358270-1|AAQ88637.1| 341|Homo sapiens RDH10 protein.
Length = 341
Score = 44.0 bits (99), Expect = 5e-04
Identities = 37/137 (27%), Positives = 62/137 (45%), Gaps = 4/137 (2%)
Frame = +3
Query: 186 TADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYY 365
T D+ K ++ ++ G++ VLVNNAG++ + +R M N + ++
Sbjct: 116 TCDVGKRENVYLTAERVRKEVGEVSVLVNNAGVVSGHHLLECPDELIERTMMVNCHAHFW 175
Query: 366 LTMLAVPHLLE-SKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALEL--APK-G 533
T +P +LE + G G+ S GV Y SK V F ++ EL A K G
Sbjct: 176 TTKAFLPTMLEINHGHIVTVASSLGLFSTAGVEDYCASKFGVVGFHESLSHELKAAEKDG 235
Query: 534 VRVNCVNPGVILTELQR 584
++ V P ++ T + R
Sbjct: 236 IKTTLVCPYLVDTGMFR 252
>AF456765-1|AAN64747.1| 341|Homo sapiens retinol dehydrogenase 10
protein.
Length = 341
Score = 44.0 bits (99), Expect = 5e-04
Identities = 37/137 (27%), Positives = 62/137 (45%), Gaps = 4/137 (2%)
Frame = +3
Query: 186 TADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYY 365
T D+ K ++ ++ G++ VLVNNAG++ + +R M N + ++
Sbjct: 116 TCDVGKRENVYLTAERVRKEVGEVSVLVNNAGVVSGHHLLECPDELIERTMMVNCHAHFW 175
Query: 366 LTMLAVPHLLE-SKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALEL--APK-G 533
T +P +LE + G G+ S GV Y SK V F ++ EL A K G
Sbjct: 176 TTKAFLPTMLEINHGHIVTVASSLGLFSTAGVEDYCASKFGVVGFHESLSHELKAAEKDG 235
Query: 534 VRVNCVNPGVILTELQR 584
++ V P ++ T + R
Sbjct: 236 IKTTLVCPYLVDTGMFR 252
>U89717-1|AAB93668.1| 318|Homo sapiens 9-cis-retinol specific
dehydrogenase protein.
Length = 318
Score = 43.6 bits (98), Expect = 7e-04
Identities = 44/180 (24%), Positives = 74/180 (41%), Gaps = 1/180 (0%)
Frame = +3
Query: 111 LTGRNVENLQKVSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIE 290
LT E+LQ V+ F +TL D K ++ + G L LVNNAG+
Sbjct: 60 LTPSGAEDLQGVASS--GFNTTLLDITDPQSFQQAAKWVEMHVKEAG-LFGLVNNAGVAG 116
Query: 291 T-GTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAY 467
G + + R++N N +T+ +P L +++G G + G Y
Sbjct: 117 IIGPTPWLTRDDFQRVLNVNTMGPIGVTLALLPLLQQARGRVINITSVLGRLAANGG-GY 175
Query: 468 NISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAAFLERTKETHA 647
+SK ++ F+ + ++A G+R + V PG T + L + A + T A
Sbjct: 176 CVSKFGLEAFSDSLRRDVAHFGIRESIVEPGFFRTPVTNLESLEKTLQACWARLPPATQA 235
>BC002730-1|AAH02730.1| 302|Homo sapiens dehydrogenase/reductase
(SDR family) member 3 protein.
Length = 302
Score = 43.6 bits (98), Expect = 7e-04
Identities = 35/169 (20%), Positives = 70/169 (41%), Gaps = 3/169 (1%)
Frame = +3
Query: 81 FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLS-ITADLTKESDIEKIIKKTIDHYGKL 257
F + ++ L GR + L++ +++ + + D+ ++ + K + G +
Sbjct: 58 FAERGARKIVLWGRTEKCLKETTEEIRQMGTECHYFICDVGNREEVYQTAKAVREKVGDI 117
Query: 258 DVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLE-SKGXXXXXXXXX 434
+LVNNA ++ ++ ++ + + N ++ T +P +LE G
Sbjct: 118 TILVNNAAVVHGKSLMDSDDDALLKSQHINTLGQFWTTKAFLPRMLELQNGHIVCLNSVL 177
Query: 435 GIRSFPGVLAYNISKASVDQFTRCVALELAP-KGVRVNCVNPGVILTEL 578
+ + PG + Y SKAS F + L L GV V P TE+
Sbjct: 178 ALSAIPGAIDYCTSKASAFAFMESLTLGLLDCPGVSATTVLPFHTSTEM 226
>AL645761-1|CAI14999.1| 302|Homo sapiens dehydrogenase/reductase
(SDR family) member 3 protein.
Length = 302
Score = 43.6 bits (98), Expect = 7e-04
Identities = 35/169 (20%), Positives = 70/169 (41%), Gaps = 3/169 (1%)
Frame = +3
Query: 81 FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLS-ITADLTKESDIEKIIKKTIDHYGKL 257
F + ++ L GR + L++ +++ + + D+ ++ + K + G +
Sbjct: 58 FAERGARKIVLWGRTEKCLKETTEEIRQMGTECHYFICDVGNREEVYQTAKAVREKVGDI 117
Query: 258 DVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLE-SKGXXXXXXXXX 434
+LVNNA ++ ++ ++ + + N ++ T +P +LE G
Sbjct: 118 TILVNNAAVVHGKSLMDSDDDALLKSQHINTLGQFWTTKAFLPRMLELQNGHIVCLNSVL 177
Query: 435 GIRSFPGVLAYNISKASVDQFTRCVALELAP-KGVRVNCVNPGVILTEL 578
+ + PG + Y SKAS F + L L GV V P TE+
Sbjct: 178 ALSAIPGAIDYCTSKASAFAFMESLTLGLLDCPGVSATTVLPFHTSTEM 226
>AL513016-1|CAH74172.1| 302|Homo sapiens dehydrogenase/reductase
(SDR family) member 3 protein.
Length = 302
Score = 43.6 bits (98), Expect = 7e-04
Identities = 35/169 (20%), Positives = 70/169 (41%), Gaps = 3/169 (1%)
Frame = +3
Query: 81 FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLS-ITADLTKESDIEKIIKKTIDHYGKL 257
F + ++ L GR + L++ +++ + + D+ ++ + K + G +
Sbjct: 58 FAERGARKIVLWGRTEKCLKETTEEIRQMGTECHYFICDVGNREEVYQTAKAVREKVGDI 117
Query: 258 DVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLE-SKGXXXXXXXXX 434
+LVNNA ++ ++ ++ + + N ++ T +P +LE G
Sbjct: 118 TILVNNAAVVHGKSLMDSDDDALLKSQHINTLGQFWTTKAFLPRMLELQNGHIVCLNSVL 177
Query: 435 GIRSFPGVLAYNISKASVDQFTRCVALELAP-KGVRVNCVNPGVILTEL 578
+ + PG + Y SKAS F + L L GV V P TE+
Sbjct: 178 ALSAIPGAIDYCTSKASAFAFMESLTLGLLDCPGVSATTVLPFHTSTEM 226
>AK222593-1|BAD96313.1| 302|Homo sapiens dehydrogenase/reductase
(SDR family) member 3 variant protein.
Length = 302
Score = 43.6 bits (98), Expect = 7e-04
Identities = 35/169 (20%), Positives = 70/169 (41%), Gaps = 3/169 (1%)
Frame = +3
Query: 81 FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLS-ITADLTKESDIEKIIKKTIDHYGKL 257
F + ++ L GR + L++ +++ + + D+ ++ + K + G +
Sbjct: 58 FAERGARKIVLWGRTEKCLKETTEEIRQMGTECHYFICDVGNREEVYQTAKAVREKVGDI 117
Query: 258 DVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLE-SKGXXXXXXXXX 434
+LVNNA ++ ++ ++ + + N ++ T +P +LE G
Sbjct: 118 TILVNNAAVVHGKSLMDSDDDALLKSQHINTLGQFWTTKAFLPRMLELQNGHIVCLNSVL 177
Query: 435 GIRSFPGVLAYNISKASVDQFTRCVALELAP-KGVRVNCVNPGVILTEL 578
+ + PG + Y SKAS F + L L GV V P TE+
Sbjct: 178 ALSAIPGAIDYCTSKASAFAFMESLTLGLLDCPGVSATTVLPFHTSTEM 226
>AF179237-1|AAD55402.1| 302|Homo sapiens short-chain
dehydrogenase/reductase 1 protein.
Length = 302
Score = 43.6 bits (98), Expect = 7e-04
Identities = 35/169 (20%), Positives = 70/169 (41%), Gaps = 3/169 (1%)
Frame = +3
Query: 81 FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLS-ITADLTKESDIEKIIKKTIDHYGKL 257
F + ++ L GR + L++ +++ + + D+ ++ + K + G +
Sbjct: 58 FAERGARKIVLWGRTEKCLKETTEEIRQMGTECHYFICDVGNREEVYQTAKAVREKVGDI 117
Query: 258 DVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLE-SKGXXXXXXXXX 434
+LVNNA ++ ++ ++ + + N ++ T +P +LE G
Sbjct: 118 TILVNNAAVVHGKSLMDSDDDALLKSQHINTLGQFWTTKAFLPRMLELQNGHIVCLNSVL 177
Query: 435 GIRSFPGVLAYNISKASVDQFTRCVALELAP-KGVRVNCVNPGVILTEL 578
+ + PG + Y SKAS F + L L GV V P TE+
Sbjct: 178 ALSAIPGAIDYCTSKASAFAFMESLTLGLLDCPGVSATTVLPFHTSTEM 226
>AF061741-1|AAC63263.1| 302|Homo sapiens retinal short-chain
dehydrogenase/reductase retSDR1 protein.
Length = 302
Score = 43.6 bits (98), Expect = 7e-04
Identities = 35/169 (20%), Positives = 70/169 (41%), Gaps = 3/169 (1%)
Frame = +3
Query: 81 FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLS-ITADLTKESDIEKIIKKTIDHYGKL 257
F + ++ L GR + L++ +++ + + D+ ++ + K + G +
Sbjct: 58 FAERGARKIVLWGRTEKCLKETTEEIRQMGTECHYFICDVGNREEVYQTAKAVREKVGDI 117
Query: 258 DVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLE-SKGXXXXXXXXX 434
+LVNNA ++ ++ ++ + + N ++ T +P +LE G
Sbjct: 118 TILVNNAAVVHGKSLMDSDDDALLKSQHINTLGQFWTTKAFLPRMLELQNGHIVCLNSVL 177
Query: 435 GIRSFPGVLAYNISKASVDQFTRCVALELAP-KGVRVNCVNPGVILTEL 578
+ + PG + Y SKAS F + L L GV V P TE+
Sbjct: 178 ALSAIPGAIDYCTSKASAFAFMESLTLGLLDCPGVSATTVLPFHTSTEM 226
>AF057034-1|AAC39922.1| 317|Homo sapiens sterol/retinol
dehydrogenase protein.
Length = 317
Score = 43.6 bits (98), Expect = 7e-04
Identities = 37/135 (27%), Positives = 65/135 (48%), Gaps = 4/135 (2%)
Frame = +3
Query: 180 SITADLTKESDIEKI---IKKTIDHYGKLDVLVNNAGI-IETGTIENTSLAQYDRLMNTN 347
++T D+TK + +K+ + G L LVNNAGI + T E + + +++ N
Sbjct: 79 TVTLDVTKTESVAAAAQWVKECVRDKG-LWGLVNNAGISLPTAPNELLTKQDFVTILDVN 137
Query: 348 VRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAP 527
+ + +T+ +P + +++G G S G Y ISK V+ F+ + EL+
Sbjct: 138 LLGVIDVTLSLLPLVRKARGRVVNVSSVMGRVSLFGG-GYCISKYGVEAFSDSLRRELSY 196
Query: 528 KGVRVNCVNPGVILT 572
GV+V + PG T
Sbjct: 197 FGVKVAMIEPGYFKT 211
>BC009881-1|AAH09881.1| 260|Homo sapiens retinol dehydrogenase 13
(all-trans/9-cis) protein.
Length = 260
Score = 43.2 bits (97), Expect = 9e-04
Identities = 37/154 (24%), Positives = 66/154 (42%), Gaps = 12/154 (7%)
Frame = +3
Query: 192 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETG--TIENTSLAQYD----------RL 335
DL I + K I+ ++D+L+NNAG++ T E+ Q+ L
Sbjct: 26 DLASLKSIREFAAKIIEEEERVDILINNAGVMRCPHWTTEDGFEMQFGVNHLGHFLLTNL 85
Query: 336 MNTNVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVAL 515
+ +++ ++ + L G R + AY SK ++ FT+ ++
Sbjct: 86 LLDKLKASAPSRIINLSSLAHVAGHIDFDDLNWQTRKYNTKAAYCQSKLAIVLFTKELSR 145
Query: 516 ELAPKGVRVNCVNPGVILTELQRRGGLSEEQYAA 617
L GV VN ++PGV TEL R G+ +++
Sbjct: 146 RLQGSGVTVNALHPGVARTELGRHTGIHGSTFSS 179
>AF086735-1|AAC72923.1| 317|Homo sapiens retinol dehydrogenase
protein.
Length = 317
Score = 42.7 bits (96), Expect = 0.001
Identities = 40/136 (29%), Positives = 64/136 (47%), Gaps = 5/136 (3%)
Frame = +3
Query: 180 SITADLTKESDIEKI---IKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRL--MNT 344
++T D+TK + +K+ + G L LVNNAGI T N L + D L ++
Sbjct: 79 TVTLDVTKTESVAAAAQWVKECVRDKG-LWGLVNNAGI-SLPTAPNELLTKQDLLTILDV 136
Query: 345 NVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELA 524
N+ + +T+ +P + ++G G S G Y ISK V+ F+ + EL+
Sbjct: 137 NLLGVIDVTLNLLPLVRRARGRVVNVFSVMGRVSLFGG-GYCISKYGVEAFSDSLRRELS 195
Query: 525 PKGVRVNCVNPGVILT 572
GV+V + PG T
Sbjct: 196 YFGVKVAMIEPGYFKT 211
>D82061-1|BAA11529.1| 259|Homo sapiens a member of the short-chain
alcohol dehydrogenase family protein.
Length = 259
Score = 42.3 bits (95), Expect = 0.002
Identities = 30/111 (27%), Positives = 51/111 (45%), Gaps = 2/111 (1%)
Frame = +3
Query: 261 VLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLES--KGXXXXXXXXX 434
V+V+ AGI + + + S +D+++ N++ + +T A L+ + +G
Sbjct: 97 VVVSCAGITQDEFLLHMSRDDWDKVIAVNLKGTFLVTQAAAQALVSNGCRGSIINISSIV 156
Query: 435 GIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRR 587
G G Y SKA V T+ A EL G+ N V PG I T + ++
Sbjct: 157 GKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIPCNSVLPGFIATPMTKK 207
>U78302-1|AAB88724.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase
protein.
Length = 335
Score = 41.9 bits (94), Expect = 0.002
Identities = 39/191 (20%), Positives = 76/191 (39%), Gaps = 4/191 (2%)
Frame = +3
Query: 15 NFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTL--SIT 188
+F GKV LS LGAQ + R ++ L+ ++ +I
Sbjct: 56 SFQGKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDVLKATAEQISSQTGNKVHAIQ 115
Query: 189 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL 368
D+ ++ + + I G ++++NNA E S + + + + ++
Sbjct: 116 CDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSPNAWKTITDIVLNGTAFV 175
Query: 369 TMLAVPHLLES-KGXXXXXXXXXGIRSFPGVLAYNIS-KASVDQFTRCVALELAPKGVRV 542
T+ L+++ KG + G + + S KA V+ ++ +A E G+R
Sbjct: 176 TLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLAAEWGKYGMRF 235
Query: 543 NCVNPGVILTE 575
N + PG I T+
Sbjct: 236 NVIQPGPIKTK 246
>U49352-1|AAB09423.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase
protein.
Length = 335
Score = 41.9 bits (94), Expect = 0.002
Identities = 39/191 (20%), Positives = 76/191 (39%), Gaps = 4/191 (2%)
Frame = +3
Query: 15 NFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTL--SIT 188
+F GKV LS LGAQ + R ++ L+ ++ +I
Sbjct: 56 SFQGKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDVLKATAEQISSQTGNKVHAIQ 115
Query: 189 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL 368
D+ ++ + + I G ++++NNA E S + + + + ++
Sbjct: 116 CDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSPNAWKTITDIVLNGTAFV 175
Query: 369 TMLAVPHLLES-KGXXXXXXXXXGIRSFPGVLAYNIS-KASVDQFTRCVALELAPKGVRV 542
T+ L+++ KG + G + + S KA V+ ++ +A E G+R
Sbjct: 176 TLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLAAEWGKYGMRF 235
Query: 543 NCVNPGVILTE 575
N + PG I T+
Sbjct: 236 NVIQPGPIKTK 246
>L26050-1|AAA67551.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase
protein.
Length = 335
Score = 41.9 bits (94), Expect = 0.002
Identities = 39/191 (20%), Positives = 76/191 (39%), Gaps = 4/191 (2%)
Frame = +3
Query: 15 NFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTL--SIT 188
+F GKV LS LGAQ + R ++ L+ ++ +I
Sbjct: 56 SFQGKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDVLKATAEQISSQTGNKVHAIQ 115
Query: 189 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL 368
D+ ++ + + I G ++++NNA E S + + + + ++
Sbjct: 116 CDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSPNAWKTITDIVLNGTAFV 175
Query: 369 TMLAVPHLLES-KGXXXXXXXXXGIRSFPGVLAYNIS-KASVDQFTRCVALELAPKGVRV 542
T+ L+++ KG + G + + S KA V+ ++ +A E G+R
Sbjct: 176 TLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLAAEWGKYGMRF 235
Query: 543 NCVNPGVILTE 575
N + PG I T+
Sbjct: 236 NVIQPGPIKTK 246
>BC105082-1|AAI05083.1| 335|Homo sapiens 2,4-dienoyl CoA reductase
1, mitochondrial protein.
Length = 335
Score = 41.9 bits (94), Expect = 0.002
Identities = 39/191 (20%), Positives = 76/191 (39%), Gaps = 4/191 (2%)
Frame = +3
Query: 15 NFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTL--SIT 188
+F GKV LS LGAQ + R ++ L+ ++ +I
Sbjct: 56 SFQGKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDVLKATAEQISSQTGNKVHAIQ 115
Query: 189 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL 368
D+ ++ + + I G ++++NNA E S + + + + ++
Sbjct: 116 CDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSPNAWKTITDIVLNGTAFV 175
Query: 369 TMLAVPHLLES-KGXXXXXXXXXGIRSFPGVLAYNIS-KASVDQFTRCVALELAPKGVRV 542
T+ L+++ KG + G + + S KA V+ ++ +A E G+R
Sbjct: 176 TLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLAAEWGKYGMRF 235
Query: 543 NCVNPGVILTE 575
N + PG I T+
Sbjct: 236 NVIQPGPIKTK 246
>BC105080-1|AAI05081.1| 335|Homo sapiens 2,4-dienoyl CoA reductase
1, mitochondrial protein.
Length = 335
Score = 41.9 bits (94), Expect = 0.002
Identities = 39/191 (20%), Positives = 76/191 (39%), Gaps = 4/191 (2%)
Frame = +3
Query: 15 NFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTL--SIT 188
+F GKV LS LGAQ + R ++ L+ ++ +I
Sbjct: 56 SFQGKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDVLKATAEQISSQTGNKVHAIQ 115
Query: 189 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL 368
D+ ++ + + I G ++++NNA E S + + + + ++
Sbjct: 116 CDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSPNAWKTITDIVLNGTAFV 175
Query: 369 TMLAVPHLLES-KGXXXXXXXXXGIRSFPGVLAYNIS-KASVDQFTRCVALELAPKGVRV 542
T+ L+++ KG + G + + S KA V+ ++ +A E G+R
Sbjct: 176 TLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLAAEWGKYGMRF 235
Query: 543 NCVNPGVILTE 575
N + PG I T+
Sbjct: 236 NVIQPGPIKTK 246
>AC004612-1|AAC14671.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase
precursor protein.
Length = 335
Score = 41.9 bits (94), Expect = 0.002
Identities = 39/191 (20%), Positives = 76/191 (39%), Gaps = 4/191 (2%)
Frame = +3
Query: 15 NFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTL--SIT 188
+F GKV LS LGAQ + R ++ L+ ++ +I
Sbjct: 56 SFQGKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDVLKATAEQISSQTGNKVHAIQ 115
Query: 189 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL 368
D+ ++ + + I G ++++NNA E S + + + + ++
Sbjct: 116 CDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSPNAWKTITDIVLNGTAFV 175
Query: 369 TMLAVPHLLES-KGXXXXXXXXXGIRSFPGVLAYNIS-KASVDQFTRCVALELAPKGVRV 542
T+ L+++ KG + G + + S KA V+ ++ +A E G+R
Sbjct: 176 TLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLAAEWGKYGMRF 235
Query: 543 NCVNPGVILTE 575
N + PG I T+
Sbjct: 236 NVIQPGPIKTK 246
>CR457356-1|CAG33637.1| 181|Homo sapiens MGC4172 protein.
Length = 181
Score = 41.1 bits (92), Expect = 0.004
Identities = 37/139 (26%), Positives = 62/139 (44%), Gaps = 8/139 (5%)
Frame = +3
Query: 243 HYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLE---SKGXX 413
H G +D+ +NNAG+ T+ + S + + + N NV ++ T A + E G
Sbjct: 9 HSG-VDICINNAGLARPDTLLSGSTSGWKDMFNVNVLALSICTREAYQSMKERNVDDGHI 67
Query: 414 XXXXXXXGIRSFPGVLA--YNISKASVDQFTRCVALEL--APKGVRVNCVNPGVILTELQ 581
G R P + Y+ +K +V T + EL A +R C++PGV+ T+
Sbjct: 68 ININSMSGHRVLPLSVTHFYSATKYAVTALTEGLRQELREAQTHIRATCISPGVVETQFA 127
Query: 582 -RRGGLSEEQYAAFLERTK 635
+ E+ AA E+ K
Sbjct: 128 FKLHDKDPEKAAATYEQMK 146
>AL645761-2|CAI15000.1| 147|Homo sapiens dehydrogenase/reductase
(SDR family) member 3 protein.
Length = 147
Score = 41.1 bits (92), Expect = 0.004
Identities = 30/131 (22%), Positives = 54/131 (41%), Gaps = 2/131 (1%)
Frame = +3
Query: 192 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLT 371
D+ ++ + K + G + +LVNNA ++ ++ ++ + + N ++ T
Sbjct: 11 DVGNREEVYQTAKAVREKVGDITILVNNAAVVHGKSLMDSDDDALLKSQHINTLGQFWTT 70
Query: 372 MLAVPHLLE-SKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAP-KGVRVN 545
+P +LE G + + PG + Y SKAS F + L L GV
Sbjct: 71 KAFLPRMLELQNGHIVCLNSVLALSAIPGAIDYCTSKASAFAFMESLTLGLLDCPGVSAT 130
Query: 546 CVNPGVILTEL 578
V P TE+
Sbjct: 131 TVLPFHTSTEM 141
>AK026196-1|BAB15390.1| 181|Homo sapiens protein ( Homo sapiens
cDNA: FLJ22543 fis, clone HSI00212. ).
Length = 181
Score = 41.1 bits (92), Expect = 0.004
Identities = 37/139 (26%), Positives = 62/139 (44%), Gaps = 8/139 (5%)
Frame = +3
Query: 243 HYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLE---SKGXX 413
H G +D+ +NNAG+ T+ + S + + + N NV ++ T A + E G
Sbjct: 9 HSG-VDICINNAGLARPDTLLSGSTSGWKDMFNVNVLALSICTREAYQSMKERNVDDGHI 67
Query: 414 XXXXXXXGIRSFPGVLA--YNISKASVDQFTRCVALEL--APKGVRVNCVNPGVILTELQ 581
G R P + Y+ +K +V T + EL A +R C++PGV+ T+
Sbjct: 68 ININSMSGHRVLPLSVTHFYSATKYAVTALTEGLRQELREAQTHIRATCISPGVVETQFA 127
Query: 582 -RRGGLSEEQYAAFLERTK 635
+ E+ AA E+ K
Sbjct: 128 FKLHDKDPEKAAATYEQMK 146
>BC058883-1|AAH58883.1| 319|Homo sapiens dehydrogenase/reductase
(SDR family) member 9 protein.
Length = 319
Score = 40.7 bits (91), Expect = 0.005
Identities = 31/138 (22%), Positives = 65/138 (47%), Gaps = 5/138 (3%)
Frame = +3
Query: 180 SITADLTKESDIEKIIKKTIDHYGKLDV--LVNNAGIIETGTIENT---SLAQYDRLMNT 344
++ D+T ++++ + + G+ + L+NNAG+ G + T +L Y +
Sbjct: 79 TVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGV--PGVLAPTDWLTLEDYREPIEV 136
Query: 345 NVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELA 524
N+ + +T+ +P + +++G G + G Y SK +V+ F + ++
Sbjct: 137 NLFGLISVTLNMLPLVKKAQGRVINVSSVGGRLAIVGG-GYTPSKYAVEGFNDSLRRDMK 195
Query: 525 PKGVRVNCVNPGVILTEL 578
GV V+C+ PG+ T L
Sbjct: 196 AFGVHVSCIEPGLFKTNL 213
>AY359046-1|AAQ89405.1| 319|Homo sapiens RDHL protein.
Length = 319
Score = 40.7 bits (91), Expect = 0.005
Identities = 31/138 (22%), Positives = 65/138 (47%), Gaps = 5/138 (3%)
Frame = +3
Query: 180 SITADLTKESDIEKIIKKTIDHYGKLDV--LVNNAGIIETGTIENT---SLAQYDRLMNT 344
++ D+T ++++ + + G+ + L+NNAG+ G + T +L Y +
Sbjct: 79 TVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGV--PGVLAPTDWLTLEDYREPIEV 136
Query: 345 NVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELA 524
N+ + +T+ +P + +++G G + G Y SK +V+ F + ++
Sbjct: 137 NLFGLISVTLNMLPLVKKAQGRVINVSSVGGRLAIVGG-GYTPSKYAVEGFNDSLRRDMK 195
Query: 525 PKGVRVNCVNPGVILTEL 578
GV V+C+ PG+ T L
Sbjct: 196 AFGVHVSCIEPGLFKTNL 213
>AY017349-1|AAG49422.1| 319|Homo sapiens retinol dehydrogenase
protein.
Length = 319
Score = 40.7 bits (91), Expect = 0.005
Identities = 31/138 (22%), Positives = 65/138 (47%), Gaps = 5/138 (3%)
Frame = +3
Query: 180 SITADLTKESDIEKIIKKTIDHYGKLDV--LVNNAGIIETGTIENT---SLAQYDRLMNT 344
++ D+T ++++ + + G+ + L+NNAG+ G + T +L Y +
Sbjct: 79 TVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGV--PGVLAPTDWLTLEDYREPIEV 136
Query: 345 NVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELA 524
N+ + +T+ +P + +++G G + G Y SK +V+ F + ++
Sbjct: 137 NLFGLISVTLNMLPLVKKAQGRVINVSSVGGRLAIVGG-GYTPSKYAVEGFNDSLRRDMK 195
Query: 525 PKGVRVNCVNPGVILTEL 578
GV V+C+ PG+ T L
Sbjct: 196 AFGVHVSCIEPGLFKTNL 213
>AF529288-1|AAN04010.1| 319|Homo sapiens microsomal NADP-dependent
retinol dehydrogenase/reductase transcript A protein.
Length = 319
Score = 40.7 bits (91), Expect = 0.005
Identities = 31/138 (22%), Positives = 65/138 (47%), Gaps = 5/138 (3%)
Frame = +3
Query: 180 SITADLTKESDIEKIIKKTIDHYGKLDV--LVNNAGIIETGTIENT---SLAQYDRLMNT 344
++ D+T ++++ + + G+ + L+NNAG+ G + T +L Y +
Sbjct: 79 TVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGV--PGVLAPTDWLTLEDYREPIEV 136
Query: 345 NVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELA 524
N+ + +T+ +P + +++G G + G Y SK +V+ F + ++
Sbjct: 137 NLFGLISVTLNMLPLVKKAQGRVINVSSVGGRLAIVGG-GYTPSKYAVEGFNDSLRRDMK 195
Query: 525 PKGVRVNCVNPGVILTEL 578
GV V+C+ PG+ T L
Sbjct: 196 AFGVHVSCIEPGLFKTNL 213
>AF529287-1|AAN04009.1| 319|Homo sapiens microsomal NADP-dependent
retinol dehydrogenase/reductase transcript B protein.
Length = 319
Score = 40.7 bits (91), Expect = 0.005
Identities = 31/138 (22%), Positives = 65/138 (47%), Gaps = 5/138 (3%)
Frame = +3
Query: 180 SITADLTKESDIEKIIKKTIDHYGKLDV--LVNNAGIIETGTIENT---SLAQYDRLMNT 344
++ D+T ++++ + + G+ + L+NNAG+ G + T +L Y +
Sbjct: 79 TVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGV--PGVLAPTDWLTLEDYREPIEV 136
Query: 345 NVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELA 524
N+ + +T+ +P + +++G G + G Y SK +V+ F + ++
Sbjct: 137 NLFGLISVTLNMLPLVKKAQGRVINVSSVGGRLAIVGG-GYTPSKYAVEGFNDSLRRDMK 195
Query: 525 PKGVRVNCVNPGVILTEL 578
GV V+C+ PG+ T L
Sbjct: 196 AFGVHVSCIEPGLFKTNL 213
>AF529286-1|AAN04008.1| 319|Homo sapiens microsomal NADP-dependent
retinol dehydrogenase/reductase transcript C protein.
Length = 319
Score = 40.7 bits (91), Expect = 0.005
Identities = 31/138 (22%), Positives = 65/138 (47%), Gaps = 5/138 (3%)
Frame = +3
Query: 180 SITADLTKESDIEKIIKKTIDHYGKLDV--LVNNAGIIETGTIENT---SLAQYDRLMNT 344
++ D+T ++++ + + G+ + L+NNAG+ G + T +L Y +
Sbjct: 79 TVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGV--PGVLAPTDWLTLEDYREPIEV 136
Query: 345 NVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELA 524
N+ + +T+ +P + +++G G + G Y SK +V+ F + ++
Sbjct: 137 NLFGLISVTLNMLPLVKKAQGRVINVSSVGGRLAIVGG-GYTPSKYAVEGFNDSLRRDMK 195
Query: 525 PKGVRVNCVNPGVILTEL 578
GV V+C+ PG+ T L
Sbjct: 196 AFGVHVSCIEPGLFKTNL 213
>AF343729-1|AAK37528.1| 319|Homo sapiens 3-alpha hydroxysteroid
dehydrogenase protein.
Length = 319
Score = 40.7 bits (91), Expect = 0.005
Identities = 31/138 (22%), Positives = 65/138 (47%), Gaps = 5/138 (3%)
Frame = +3
Query: 180 SITADLTKESDIEKIIKKTIDHYGKLDV--LVNNAGIIETGTIENT---SLAQYDRLMNT 344
++ D+T ++++ + + G+ + L+NNAG+ G + T +L Y +
Sbjct: 79 TVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGV--PGVLAPTDWLTLEDYREPIEV 136
Query: 345 NVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELA 524
N+ + +T+ +P + +++G G + G Y SK +V+ F + ++
Sbjct: 137 NLFGLISVTLNMLPLVKKAQGRVINVSSVGGRLAIVGG-GYTPSKYAVEGFNDSLRRDMK 195
Query: 525 PKGVRVNCVNPGVILTEL 578
GV V+C+ PG+ T L
Sbjct: 196 AFGVHVSCIEPGLFKTNL 213
>AF295380-1|AAL37037.1| 319|Homo sapiens short-chain
dehydrogenase/reductase RETSDR8 protein.
Length = 319
Score = 40.7 bits (91), Expect = 0.005
Identities = 31/138 (22%), Positives = 65/138 (47%), Gaps = 5/138 (3%)
Frame = +3
Query: 180 SITADLTKESDIEKIIKKTIDHYGKLDV--LVNNAGIIETGTIENT---SLAQYDRLMNT 344
++ D+T ++++ + + G+ + L+NNAG+ G + T +L Y +
Sbjct: 79 TVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGV--PGVLAPTDWLTLEDYREPIEV 136
Query: 345 NVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELA 524
N+ + +T+ +P + +++G G + G Y SK +V+ F + ++
Sbjct: 137 NLFGLISVTLNMLPLVKKAQGRVINVSSVGGRLAIVGG-GYTPSKYAVEGFNDSLRRDMK 195
Query: 525 PKGVRVNCVNPGVILTEL 578
GV V+C+ PG+ T L
Sbjct: 196 AFGVHVSCIEPGLFKTNL 213
>AC008177-2|AAY24306.1| 245|Homo sapiens unknown protein.
Length = 245
Score = 40.7 bits (91), Expect = 0.005
Identities = 31/138 (22%), Positives = 65/138 (47%), Gaps = 5/138 (3%)
Frame = +3
Query: 180 SITADLTKESDIEKIIKKTIDHYGKLDV--LVNNAGIIETGTIENT---SLAQYDRLMNT 344
++ D+T ++++ + + G+ + L+NNAG+ G + T +L Y +
Sbjct: 79 TVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGV--PGVLAPTDWLTLEDYREPIEV 136
Query: 345 NVRSIYYLTMLAVPHLLESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELA 524
N+ + +T+ +P + +++G G + G Y SK +V+ F + ++
Sbjct: 137 NLFGLISVTLNMLPLVKKAQGRVINVSSVGGRLAIVGG-GYTPSKYAVEGFNDSLRRDMK 195
Query: 525 PKGVRVNCVNPGVILTEL 578
GV V+C+ PG+ T L
Sbjct: 196 AFGVHVSCIEPGLFKTNL 213
>Z97054-7|CAI42652.1| 252|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 10 protein.
Length = 252
Score = 40.3 bits (90), Expect = 0.006
Identities = 31/129 (24%), Positives = 58/129 (44%), Gaps = 13/129 (10%)
Frame = +3
Query: 189 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENT------SLAQYDRLMNTNV 350
AD+T E D++ + +G++DV VN AGI N +L + R+++ N+
Sbjct: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122
Query: 351 RSIYYLTMLAVPHLLESK----GXXXXXXXXXGIRSFPGVL---AYNISKASVDQFTRCV 509
+ + L + +++ G + +F G + AY+ SK + T +
Sbjct: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182
Query: 510 ALELAPKGV 536
A +LAP G+
Sbjct: 183 ARDLAPIGL 191
>BC008708-1|AAH08708.1| 252|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 10 protein.
Length = 252
Score = 40.3 bits (90), Expect = 0.006
Identities = 31/129 (24%), Positives = 58/129 (44%), Gaps = 13/129 (10%)
Frame = +3
Query: 189 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENT------SLAQYDRLMNTNV 350
AD+T E D++ + +G++DV VN AGI N +L + R+++ N+
Sbjct: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122
Query: 351 RSIYYLTMLAVPHLLESK----GXXXXXXXXXGIRSFPGVL---AYNISKASVDQFTRCV 509
+ + L + +++ G + +F G + AY+ SK + T +
Sbjct: 123 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 182
Query: 510 ALELAPKGV 536
A +LAP G+
Sbjct: 183 ARDLAPIGL 191
>CR457145-1|CAG33426.1| 157|Homo sapiens PECR protein.
Length = 157
Score = 39.9 bits (89), Expect = 0.008
Identities = 18/43 (41%), Positives = 27/43 (62%)
Frame = +3
Query: 447 FPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTE 575
FP + ++A V T+ +ALE A G+R+NCV PGVI ++
Sbjct: 19 FPLAVHSGAARAGVYNLTKSLALEWACSGIRINCVAPGVIYSQ 61
>BC064525-1|AAH64525.1| 309|Homo sapiens epidermal retinal
dehydrogenase 2 protein.
Length = 309
Score = 38.7 bits (86), Expect = 0.019
Identities = 38/192 (19%), Positives = 75/192 (39%), Gaps = 6/192 (3%)
Frame = +3
Query: 15 NFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTL--SIT 188
N AG++V ++LG+ L L N E ++ K + +T + T
Sbjct: 37 NVAGEIVLITGAGSGLGRLLALQFARLGSVLVLWDINKEGNEETCKMAREAGATRVHAYT 96
Query: 189 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL 368
D +++ + ++ + G + +L+NNAGI+ + ++ + N ++ +
Sbjct: 97 CDCSQKEGVYRVADQVKKEVGDVSILINNAGIVTGKKFLDCPDELMEKSFDVNFKAHLWT 156
Query: 369 TMLAVPHLL-ESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALEL---APKGV 536
+P ++ G G+ G+ Y SK + F V +E KG+
Sbjct: 157 YKAFLPAMIANDHGHLVCISSSAGLSGVNGLADYCASKFAAFGFAESVFVETFVQKQKGI 216
Query: 537 RVNCVNPGVILT 572
+ V P I T
Sbjct: 217 KTTIVCPFFIKT 228
>BC037219-1|AAH37219.2| 309|Homo sapiens epidermal retinal
dehydrogenase 2 protein.
Length = 309
Score = 38.7 bits (86), Expect = 0.019
Identities = 38/192 (19%), Positives = 75/192 (39%), Gaps = 6/192 (3%)
Frame = +3
Query: 15 NFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTL--SIT 188
N AG++V ++LG+ L L N E ++ K + +T + T
Sbjct: 37 NVAGEIVLITGAGSGLGRLLALQFARLGSVLVLWDINKEGNEETCKMAREAGATRVHAYT 96
Query: 189 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL 368
D +++ + ++ + G + +L+NNAGI+ + ++ + N ++ +
Sbjct: 97 CDCSQKEGVYRVADQVKKEVGDVSILINNAGIVTGKKFLDCPDELMEKSFDVNFKAHLWT 156
Query: 369 TMLAVPHLL-ESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALEL---APKGV 536
+P ++ G G+ G+ Y SK + F V +E KG+
Sbjct: 157 YKAFLPAMIANDHGHLVCISSSAGLSGVNGLADYCASKFAAFGFAESVFVETFVQKQKGI 216
Query: 537 RVNCVNPGVILT 572
+ V P I T
Sbjct: 217 KTTIVCPFFIKT 228
>AB083038-1|BAB91014.1| 309|Homo sapiens retinal short chain
dehydrogenase reductase protein.
Length = 309
Score = 38.7 bits (86), Expect = 0.019
Identities = 38/192 (19%), Positives = 75/192 (39%), Gaps = 6/192 (3%)
Frame = +3
Query: 15 NFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTL--SIT 188
N AG++V ++LG+ L L N E ++ K + +T + T
Sbjct: 37 NVAGEIVLITGAGSGLGRLLALQFARLGSVLVLWDINKEGNEETCKMAREAGATRVRAYT 96
Query: 189 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL 368
D +++ + ++ + G + +L+NNAGI+ + ++ + N ++ +
Sbjct: 97 CDCSQKEGVYRVADQVKKEIGDVSILINNAGIVTGKKFLDCPDELMEKSFDVNFKAHLWT 156
Query: 369 TMLAVPHLL-ESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALEL---APKGV 536
+P ++ G G+ G+ Y SK + F V +E KG+
Sbjct: 157 YKAFLPAMIANDHGHLVCISSSAGLSGVNGLADYCASKFAAFGFAESVFVETFVQKQKGI 216
Query: 537 RVNCVNPGVILT 572
+ V P I T
Sbjct: 217 KTTIVCPFFIKT 228
>CR457180-1|CAG33461.1| 318|Homo sapiens RDH11 protein.
Length = 318
Score = 38.3 bits (85), Expect = 0.025
Identities = 50/208 (24%), Positives = 79/208 (37%), Gaps = 16/208 (7%)
Frame = +3
Query: 9 TMNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSIT 188
T+ GKVV L++ GA++ L R+VE + V+K+ +
Sbjct: 36 TVQLPGKVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGNQQVL 95
Query: 189 A---DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSI 359
DL+ I K + L VL+NNAG++ + ++ + N
Sbjct: 96 VRKLDLSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTAD--GFEMHIGVNHLGH 153
Query: 360 YYLTMLAVPHLLESKG-------------XXXXXXXXXGIRSFPGVLAYNISKASVDQFT 500
+ LT L + L ES G + + LAY SK + FT
Sbjct: 154 FLLTHLLLEKLKESAPSRIVNVSSLAHHLGRIHFHNLQGEKFYNAGLAYCHSKLANILFT 213
Query: 501 RCVALELAPKGVRVNCVNPGVILTELQR 584
+ +A L GV V+PG + +EL R
Sbjct: 214 QELARRLKGSGVTTYSVHPGTVQSELVR 241
>BC037302-1|AAH37302.1| 318|Homo sapiens retinol dehydrogenase 11
(all-trans/9-cis/11-cis) protein.
Length = 318
Score = 38.3 bits (85), Expect = 0.025
Identities = 50/208 (24%), Positives = 79/208 (37%), Gaps = 16/208 (7%)
Frame = +3
Query: 9 TMNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSIT 188
T+ GKVV L++ GA++ L R+VE + V+K+ +
Sbjct: 36 TVQLPGKVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGNQQVL 95
Query: 189 A---DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSI 359
DL+ I K + L VL+NNAG++ + ++ + N
Sbjct: 96 VRKLDLSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTAD--GFEMHIGVNHLGH 153
Query: 360 YYLTMLAVPHLLESKG-------------XXXXXXXXXGIRSFPGVLAYNISKASVDQFT 500
+ LT L + L ES G + + LAY SK + FT
Sbjct: 154 FLLTHLLLEKLKESAPSRIVNVSSLAHHLGRIHFHNLQGEKFYNAGLAYCHSKLANILFT 213
Query: 501 RCVALELAPKGVRVNCVNPGVILTELQR 584
+ +A L GV V+PG + +EL R
Sbjct: 214 QELARRLKGSGVTTYSVHPGTVQSELVR 241
>BC026274-1|AAH26274.1| 318|Homo sapiens retinol dehydrogenase 11
(all-trans/9-cis/11-cis) protein.
Length = 318
Score = 38.3 bits (85), Expect = 0.025
Identities = 50/208 (24%), Positives = 79/208 (37%), Gaps = 16/208 (7%)
Frame = +3
Query: 9 TMNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSIT 188
T+ GKVV L++ GA++ L R+VE + V+K+ +
Sbjct: 36 TVQLPGKVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGNQQVL 95
Query: 189 A---DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSI 359
DL+ I K + L VL+NNAG++ + ++ + N
Sbjct: 96 VRKLDLSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTAD--GFEMHIGVNHLGH 153
Query: 360 YYLTMLAVPHLLESKG-------------XXXXXXXXXGIRSFPGVLAYNISKASVDQFT 500
+ LT L + L ES G + + LAY SK + FT
Sbjct: 154 FLLTHLLLEKLKESAPSRIVNVSSLAHHLGRIHFHNLQGEKFYNAGLAYCHSKLANILFT 213
Query: 501 RCVALELAPKGVRVNCVNPGVILTELQR 584
+ +A L GV V+PG + +EL R
Sbjct: 214 QELARRLKGSGVTTYSVHPGTVQSELVR 241
>BC011727-1|AAH11727.1| 318|Homo sapiens RDH11 protein protein.
Length = 318
Score = 38.3 bits (85), Expect = 0.025
Identities = 50/208 (24%), Positives = 79/208 (37%), Gaps = 16/208 (7%)
Frame = +3
Query: 9 TMNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSIT 188
T+ GKVV L++ GA++ L R+VE + V+K+ +
Sbjct: 36 TVQLPGKVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGNQQVL 95
Query: 189 A---DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSI 359
DL+ I K + L VL+NNAG++ + ++ + N
Sbjct: 96 VRKLDLSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTAD--GFEMHIGVNHLGH 153
Query: 360 YYLTMLAVPHLLESKG-------------XXXXXXXXXGIRSFPGVLAYNISKASVDQFT 500
+ LT L + L ES G + + LAY SK + FT
Sbjct: 154 FLLTHLLLEKLKESAPSRIVNVSSLAHHLGRIHFHNLQGEKFYNAGLAYCHSKLANILFT 213
Query: 501 RCVALELAPKGVRVNCVNPGVILTELQR 584
+ +A L GV V+PG + +EL R
Sbjct: 214 QELARRLKGSGVTTYSVHPGTVQSELVR 241
>BC000112-1|AAH00112.1| 318|Homo sapiens retinol dehydrogenase 11
(all-trans/9-cis/11-cis) protein.
Length = 318
Score = 38.3 bits (85), Expect = 0.025
Identities = 50/208 (24%), Positives = 79/208 (37%), Gaps = 16/208 (7%)
Frame = +3
Query: 9 TMNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSIT 188
T+ GKVV L++ GA++ L R+VE + V+K+ +
Sbjct: 36 TVQLPGKVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGNQQVL 95
Query: 189 A---DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSI 359
DL+ I K + L VL+NNAG++ + ++ + N
Sbjct: 96 VRKLDLSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTAD--GFEMHIGVNHLGH 153
Query: 360 YYLTMLAVPHLLESKG-------------XXXXXXXXXGIRSFPGVLAYNISKASVDQFT 500
+ LT L + L ES G + + LAY SK + FT
Sbjct: 154 FLLTHLLLEKLKESAPSRIVNVSSLAHHLGRIHFHNLQGEKFYNAGLAYCHSKLANILFT 213
Query: 501 RCVALELAPKGVRVNCVNPGVILTELQR 584
+ +A L GV V+PG + +EL R
Sbjct: 214 QELARRLKGSGVTTYSVHPGTVQSELVR 241
>AF395068-1|AAK72049.1| 318|Homo sapiens HCV core-binding protein
HCBP12 protein.
Length = 318
Score = 38.3 bits (85), Expect = 0.025
Identities = 50/208 (24%), Positives = 79/208 (37%), Gaps = 16/208 (7%)
Frame = +3
Query: 9 TMNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSIT 188
T+ GKVV L++ GA++ L R+VE + V+K+ +
Sbjct: 36 TVQLPGKVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGNQQVL 95
Query: 189 A---DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSI 359
DL+ I K + L VL+NNAG++ + ++ + N
Sbjct: 96 VRKLDLSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTAD--GFEMHIGVNHLGH 153
Query: 360 YYLTMLAVPHLLESKG-------------XXXXXXXXXGIRSFPGVLAYNISKASVDQFT 500
+ LT L + L ES G + + LAY SK + FT
Sbjct: 154 FLLTHLLLEKLKESAPSRIVNVSSLAHHLGRIHFHNLQGEKFYNAGLAYCHSKLANILFT 213
Query: 501 RCVALELAPKGVRVNCVNPGVILTELQR 584
+ +A L GV V+PG + +EL R
Sbjct: 214 QELARRLKGSGVTTYSVHPGTVQSELVR 241
>AF167438-1|AAF89632.1| 318|Homo sapiens androgen-regulated
short-chain dehydrogenase/reductase 1 protein.
Length = 318
Score = 38.3 bits (85), Expect = 0.025
Identities = 50/208 (24%), Positives = 79/208 (37%), Gaps = 16/208 (7%)
Frame = +3
Query: 9 TMNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSIT 188
T+ GKVV L++ GA++ L R+VE + V+K+ +
Sbjct: 36 TVQLPGKVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGNQQVL 95
Query: 189 A---DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSI 359
DL+ I K + L VL+NNAG++ + ++ + N
Sbjct: 96 VRKLDLSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTAD--GFEMHIGVNHLGH 153
Query: 360 YYLTMLAVPHLLESKG-------------XXXXXXXXXGIRSFPGVLAYNISKASVDQFT 500
+ LT L + L ES G + + LAY SK + FT
Sbjct: 154 FLLTHLLLEKLKESAPSRIVNVSSLAHHLGRIHFHNLQGEKFYNAGLAYCHSKLANILFT 213
Query: 501 RCVALELAPKGVRVNCVNPGVILTELQR 584
+ +A L GV V+PG + +EL R
Sbjct: 214 QELARRLKGSGVTTYSVHPGTVQSELVR 241
>AF151840-1|AAD34077.1| 318|Homo sapiens CGI-82 protein protein.
Length = 318
Score = 38.3 bits (85), Expect = 0.025
Identities = 50/208 (24%), Positives = 79/208 (37%), Gaps = 16/208 (7%)
Frame = +3
Query: 9 TMNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSIT 188
T+ GKVV L++ GA++ L R+VE + V+K+ +
Sbjct: 36 TVQLPGKVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGNQQVL 95
Query: 189 A---DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSI 359
DL+ I K + L VL+NNAG++ + ++ + N
Sbjct: 96 VRKLDLSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTAD--GFEMHIGVNHLGH 153
Query: 360 YYLTMLAVPHLLESKG-------------XXXXXXXXXGIRSFPGVLAYNISKASVDQFT 500
+ LT L + L ES G + + LAY SK + FT
Sbjct: 154 FLLTHLLLEKLKESAPSRIVNVSSLAHHLGRIHFHNLQGEKFYNAGLAYCHSKLANILFT 213
Query: 501 RCVALELAPKGVRVNCVNPGVILTELQR 584
+ +A L GV V+PG + +EL R
Sbjct: 214 QELARRLKGSGVTTYSVHPGTVQSELVR 241
>AK057667-1|BAB71545.1| 231|Homo sapiens protein ( Homo sapiens
cDNA FLJ33105 fis, clone TRACH2000926, weakly similar to
PROBABLE OXIDOREDUCTASE EPHD (EC 1.-.-.-). ).
Length = 231
Score = 37.5 bits (83), Expect = 0.043
Identities = 36/187 (19%), Positives = 73/187 (39%), Gaps = 6/187 (3%)
Frame = +3
Query: 15 NFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTL--SIT 188
N AG++V ++LG+ L L N E ++ K + +T + T
Sbjct: 37 NVAGEIVLITGAGSGLGRLLALQFARLGSVLVLWDINKEGNEETCKMAREAGATRVHAYT 96
Query: 189 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYL 368
D +++ + ++ + G + +L+NNAGI+ + ++ + N ++ +
Sbjct: 97 CDCSQKEGVYRVADQVKKEVGDVSILINNAGIVTGKKFLDCPDELMEKSFDVNFKAHLWT 156
Query: 369 TMLAVPHLL-ESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALEL---APKGV 536
+P ++ G G+ G+ Y SK + F V +E KG+
Sbjct: 157 YKAFLPAMIANDHGHLVCISSSAGLSGVNGLADYCASKFAAFGFAESVFVETFVQKQKGI 216
Query: 537 RVNCVNP 557
+ V P
Sbjct: 217 KTTIVCP 223
>AY268353-1|AAP42287.1| 199|Homo sapiens short-chain
dehydrogenase/reductase 10c protein.
Length = 199
Score = 36.7 bits (81), Expect = 0.076
Identities = 33/110 (30%), Positives = 47/110 (42%), Gaps = 1/110 (0%)
Frame = +3
Query: 216 EKIIKKTIDHYGKLDVLV-NNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHL 392
E +++ +D G LD LV N+ G GT + A LM N S LT A+P L
Sbjct: 8 ESVVQFALDKLGGLDYLVLNHIGGAPAGTRARSPQATR-WLMQVNFVSYVQLTSRALPSL 66
Query: 393 LESKGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRV 542
+SKG G Y+ +K ++D F + EL + V V
Sbjct: 67 TDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNV 116
>AB209653-1|BAD92890.1| 166|Homo sapiens dehydrogenase/reductase
(SDR family) member 2 isoform 2 variant protein.
Length = 166
Score = 36.7 bits (81), Expect = 0.076
Identities = 23/86 (26%), Positives = 47/86 (54%), Gaps = 2/86 (2%)
Frame = +3
Query: 84 LSKLGAQLSLTGRNVENLQK-VSKDCDKFASTLSITADLTKESDIEKIIKKTIDHYGKLD 260
L++ GA + ++ R +N+ + ++K + S I + K D E+++ K ++H G +D
Sbjct: 73 LARDGAHVVISSRKQQNVDRAMAKLQGEGLSVAGIVCHVGKAEDREQLVAKALEHCGGVD 132
Query: 261 VLVNNAGIIE-TGTIENTSLAQYDRL 335
LV +AG+ G+ TS +D++
Sbjct: 133 FLVCSAGVNPLVGSTLGTSEQIWDKV 158
>X13440-1|CAA31792.1| 328|Homo sapiens protein ( Human mRNA for
17-beta-hydroxysteroid dehydrogenase (17-HSD) (EC
1.1.1.62). ).
Length = 328
Score = 34.7 bits (76), Expect = 0.30
Identities = 26/114 (22%), Positives = 47/114 (41%), Gaps = 1/114 (0%)
Frame = +3
Query: 249 GKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHL-LESKGXXXXXX 425
G++DVLV NAG+ G +E +++ NV + +P + G
Sbjct: 83 GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQAFLPDMKRRGSGRVLVTG 142
Query: 426 XXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRR 587
G+ P Y SK +++ +A+ L P GV ++ + G + T +
Sbjct: 143 SVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLIECGPVHTAFMEK 196
>U34879-1|AAD05019.1| 328|Homo sapiens 17-beta-hydroxysteroid
dehydrogenase protein.
Length = 328
Score = 34.7 bits (76), Expect = 0.30
Identities = 26/114 (22%), Positives = 47/114 (41%), Gaps = 1/114 (0%)
Frame = +3
Query: 249 GKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHL-LESKGXXXXXX 425
G++DVLV NAG+ G +E +++ NV + +P + G
Sbjct: 83 GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQAFLPDMKRRGSGRVLVTG 142
Query: 426 XXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRR 587
G+ P Y SK +++ +A+ L P GV ++ + G + T +
Sbjct: 143 SVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLIECGPVHTAFMEK 196
>M84472-1|AAB16942.1| 328|Homo sapiens 17-beta-hydroxysteroid
dehydrogenase protein.
Length = 328
Score = 34.7 bits (76), Expect = 0.30
Identities = 26/114 (22%), Positives = 47/114 (41%), Gaps = 1/114 (0%)
Frame = +3
Query: 249 GKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHL-LESKGXXXXXX 425
G++DVLV NAG+ G +E +++ NV + +P + G
Sbjct: 83 GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQAFLPDMKRRGSGRVLVTG 142
Query: 426 XXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRR 587
G+ P Y SK +++ +A+ L P GV ++ + G + T +
Sbjct: 143 SVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLIECGPVHTAFMEK 196
>M36263-1|AAA35600.1| 328|Homo sapiens protein ( Human placental
17-beta-hydroxysteroid dehydrogenase mRNA, complete cds.
).
Length = 328
Score = 34.7 bits (76), Expect = 0.30
Identities = 26/114 (22%), Positives = 47/114 (41%), Gaps = 1/114 (0%)
Frame = +3
Query: 249 GKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHL-LESKGXXXXXX 425
G++DVLV NAG+ G +E +++ NV + +P + G
Sbjct: 83 GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQAFLPDMKRRGSGRVLVTG 142
Query: 426 XXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRR 587
G+ P Y SK +++ +A+ L P GV ++ + G + T +
Sbjct: 143 SVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLIECGPVHTAFMEK 196
>M27138-1|AAB16941.1| 328|Homo sapiens protein ( Human estradiol 17
beta-dehydrogenase gene, complete cds. ).
Length = 328
Score = 34.7 bits (76), Expect = 0.30
Identities = 26/114 (22%), Positives = 47/114 (41%), Gaps = 1/114 (0%)
Frame = +3
Query: 249 GKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHL-LESKGXXXXXX 425
G++DVLV NAG+ G +E +++ NV + +P + G
Sbjct: 83 GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQAFLPDMKRRGSGRVLVTG 142
Query: 426 XXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRR 587
G+ P Y SK +++ +A+ L P GV ++ + G + T +
Sbjct: 143 SVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLIECGPVHTAFMEK 196
>BC111935-1|AAI11936.1| 328|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 1 protein.
Length = 328
Score = 34.7 bits (76), Expect = 0.30
Identities = 26/114 (22%), Positives = 47/114 (41%), Gaps = 1/114 (0%)
Frame = +3
Query: 249 GKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHL-LESKGXXXXXX 425
G++DVLV NAG+ G +E +++ NV + +P + G
Sbjct: 83 GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQAFLPDMKRRGSGRVLVTG 142
Query: 426 XXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRR 587
G+ P Y SK +++ +A+ L P GV ++ + G + T +
Sbjct: 143 SVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLIECGPVHTAFMEK 196
>BC104752-1|AAI04753.1| 328|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 1 protein.
Length = 328
Score = 34.7 bits (76), Expect = 0.30
Identities = 26/114 (22%), Positives = 47/114 (41%), Gaps = 1/114 (0%)
Frame = +3
Query: 249 GKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHL-LESKGXXXXXX 425
G++DVLV NAG+ G +E +++ NV + +P + G
Sbjct: 83 GRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQAFLPDMKRRGSGRVLVTG 142
Query: 426 XXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRR 587
G+ P Y SK +++ +A+ L P GV ++ + G + T +
Sbjct: 143 SVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLIECGPVHTAFMEK 196
>BC009830-1|AAH09830.1| 336|Homo sapiens retinol dehydrogenase 14
(all-trans/9-cis/11-cis) protein.
Length = 336
Score = 33.5 bits (73), Expect = 0.70
Identities = 35/144 (24%), Positives = 57/144 (39%), Gaps = 13/144 (9%)
Frame = +3
Query: 192 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLT 371
DL + ++ + +LDVL+NNAGI + ++ ++ N + LT
Sbjct: 115 DLASLRSVRAFCQEMLQEEPRLDVLINNAGIFQCPYMKTED--GFEMQFGVNHLGHFLLT 172
Query: 372 MLAVPHLLES-------------KGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVA 512
L + L S K +S+ Y+ SK + FTR +A
Sbjct: 173 NLLLGLLKSSAPSRIVVVSSKLYKYGDINFDDLNSEQSYNKSFCYSRSKLANILFTRELA 232
Query: 513 LELAPKGVRVNCVNPGVILTELQR 584
L V VN ++PG++ T L R
Sbjct: 233 RRLEGTNVTVNVLHPGIVRTNLGR 256
>AY358511-1|AAQ88875.1| 336|Homo sapiens PAN2 protein.
Length = 336
Score = 33.5 bits (73), Expect = 0.70
Identities = 35/144 (24%), Positives = 57/144 (39%), Gaps = 13/144 (9%)
Frame = +3
Query: 192 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLT 371
DL + ++ + +LDVL+NNAGI + ++ ++ N + LT
Sbjct: 115 DLASLRSVRAFCQEMLQEEPRLDVLINNAGIFQCPYMKTED--GFEMQFGVNHLGHFLLT 172
Query: 372 MLAVPHLLES-------------KGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVA 512
L + L S K +S+ Y+ SK + FTR +A
Sbjct: 173 NLLLGLLKSSAPSRIVVVSSKLYKYGDINFDDLNSEQSYNKSFCYSRSKLANILFTRELA 232
Query: 513 LELAPKGVRVNCVNPGVILTELQR 584
L V VN ++PG++ T L R
Sbjct: 233 RRLEGTNVTVNVLHPGIVRTNLGR 256
>AF237952-1|AAG12190.1| 336|Homo sapiens PAN2 protein.
Length = 336
Score = 33.5 bits (73), Expect = 0.70
Identities = 35/144 (24%), Positives = 57/144 (39%), Gaps = 13/144 (9%)
Frame = +3
Query: 192 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLT 371
DL + ++ + +LDVL+NNAGI + ++ ++ N + LT
Sbjct: 115 DLASLRSVRAFCQEMLQEEPRLDVLINNAGIFQCPYMKTED--GFEMQFGVNHLGHFLLT 172
Query: 372 MLAVPHLLES-------------KGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVA 512
L + L S K +S+ Y+ SK + FTR +A
Sbjct: 173 NLLLGLLKSSAPSRIVVVSSKLYKYGDINFDDLNSEQSYNKSFCYSRSKLANILFTRELA 232
Query: 513 LELAPKGVRVNCVNPGVILTELQR 584
L V VN ++PG++ T L R
Sbjct: 233 RRLEGTNVTVNVLHPGIVRTNLGR 256
>AC079148-1|AAX93259.1| 336|Homo sapiens unknown protein.
Length = 336
Score = 33.5 bits (73), Expect = 0.70
Identities = 35/144 (24%), Positives = 57/144 (39%), Gaps = 13/144 (9%)
Frame = +3
Query: 192 DLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLT 371
DL + ++ + +LDVL+NNAGI + ++ ++ N + LT
Sbjct: 115 DLASLRSVRAFCQEMLQEEPRLDVLINNAGIFQCPYMKTED--GFEMQFGVNHLGHFLLT 172
Query: 372 MLAVPHLLES-------------KGXXXXXXXXXGIRSFPGVLAYNISKASVDQFTRCVA 512
L + L S K +S+ Y+ SK + FTR +A
Sbjct: 173 NLLLGLLKSSAPSRIVVVSSKLYKYGDINFDDLNSEQSYNKSFCYSRSKLANILFTRELA 232
Query: 513 LELAPKGVRVNCVNPGVILTELQR 584
L V VN ++PG++ T L R
Sbjct: 233 RRLEGTNVTVNVLHPGIVRTNLGR 256
>DQ426886-1|ABD90542.1| 171|Homo sapiens retinol dehydrogenase 11
protein.
Length = 171
Score = 33.1 bits (72), Expect = 0.93
Identities = 25/96 (26%), Positives = 40/96 (41%), Gaps = 3/96 (3%)
Frame = +3
Query: 9 TMNFAGKVVXXXXXXXXXXXXXXXFLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSIT 188
T+ GKVV L++ GA++ L R+VE + V+K+ +
Sbjct: 36 TVQLPGKVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGNQQVL 95
Query: 189 A---DLTKESDIEKIIKKTIDHYGKLDVLVNNAGII 287
DL+ I K + L VL+NNAG++
Sbjct: 96 VRKLDLSDTKSIRAFAKGFLAEEKHLHVLINNAGVM 131
>BC150182-1|AAI50183.1| 1192|Homo sapiens reticulon 4 protein.
Length = 1192
Score = 32.3 bits (70), Expect = 1.6
Identities = 17/46 (36%), Positives = 25/46 (54%)
Frame = +3
Query: 81 FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIE 218
+L L L G EN+ + SK+ + A TL I DLT+ S++E
Sbjct: 251 YLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE 296
>AY123250-1|AAM64254.1| 986|Homo sapiens RTN4 isoform G protein.
Length = 986
Score = 32.3 bits (70), Expect = 1.6
Identities = 17/46 (36%), Positives = 25/46 (54%)
Frame = +3
Query: 81 FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIE 218
+L L L G EN+ + SK+ + A TL I DLT+ S++E
Sbjct: 45 YLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE 90
>AY123249-1|AAM64253.1| 986|Homo sapiens RTN4 isoform F protein.
Length = 986
Score = 32.3 bits (70), Expect = 1.6
Identities = 17/46 (36%), Positives = 25/46 (54%)
Frame = +3
Query: 81 FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIE 218
+L L L G EN+ + SK+ + A TL I DLT+ S++E
Sbjct: 45 YLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE 90
>AY123248-1|AAM64252.1| 986|Homo sapiens RTN4 isoform E protein.
Length = 986
Score = 32.3 bits (70), Expect = 1.6
Identities = 17/46 (36%), Positives = 25/46 (54%)
Frame = +3
Query: 81 FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIE 218
+L L L G EN+ + SK+ + A TL I DLT+ S++E
Sbjct: 45 YLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE 90
>AY123247-1|AAM64251.1| 986|Homo sapiens RTN4 isoform D protein.
Length = 986
Score = 32.3 bits (70), Expect = 1.6
Identities = 17/46 (36%), Positives = 25/46 (54%)
Frame = +3
Query: 81 FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIE 218
+L L L G EN+ + SK+ + A TL I DLT+ S++E
Sbjct: 45 YLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE 90
>AY123246-1|AAM64250.1| 986|Homo sapiens RTN4 isoform Ab protein.
Length = 986
Score = 32.3 bits (70), Expect = 1.6
Identities = 17/46 (36%), Positives = 25/46 (54%)
Frame = +3
Query: 81 FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIE 218
+L L L G EN+ + SK+ + A TL I DLT+ S++E
Sbjct: 45 YLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE 90
>AY123245-1|AAM64249.1| 986|Homo sapiens RTN4 isoform Aa protein.
Length = 986
Score = 32.3 bits (70), Expect = 1.6
Identities = 17/46 (36%), Positives = 25/46 (54%)
Frame = +3
Query: 81 FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIE 218
+L L L G EN+ + SK+ + A TL I DLT+ S++E
Sbjct: 45 YLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE 90
>AY102285-4|AAM64244.1| 986|Homo sapiens RNT4 protein.
Length = 986
Score = 32.3 bits (70), Expect = 1.6
Identities = 17/46 (36%), Positives = 25/46 (54%)
Frame = +3
Query: 81 FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIE 218
+L L L G EN+ + SK+ + A TL I DLT+ S++E
Sbjct: 45 YLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE 90
>AY102285-1|AAM64243.1| 1192|Homo sapiens RTN4 protein.
Length = 1192
Score = 32.3 bits (70), Expect = 1.6
Identities = 17/46 (36%), Positives = 25/46 (54%)
Frame = +3
Query: 81 FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIE 218
+L L L G EN+ + SK+ + A TL I DLT+ S++E
Sbjct: 251 YLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE 296
>AY102279-1|AAM64248.1| 1192|Homo sapiens RTN4 isoform A protein.
Length = 1192
Score = 32.3 bits (70), Expect = 1.6
Identities = 17/46 (36%), Positives = 25/46 (54%)
Frame = +3
Query: 81 FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIE 218
+L L L G EN+ + SK+ + A TL I DLT+ S++E
Sbjct: 251 YLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE 296
>AJ251383-1|CAB99248.1| 1192|Homo sapiens Nogo-A protein protein.
Length = 1192
Score = 32.3 bits (70), Expect = 1.6
Identities = 17/46 (36%), Positives = 25/46 (54%)
Frame = +3
Query: 81 FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIE 218
+L L L G EN+ + SK+ + A TL I DLT+ S++E
Sbjct: 251 YLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE 296
>AF333336-1|AAK20831.1| 986|Homo sapiens testis specific reticulon
5 protein protein.
Length = 986
Score = 32.3 bits (70), Expect = 1.6
Identities = 17/46 (36%), Positives = 25/46 (54%)
Frame = +3
Query: 81 FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIE 218
+L L L G EN+ + SK+ + A TL I DLT+ S++E
Sbjct: 45 YLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE 90
>AF148537-1|AAG12176.1| 1192|Homo sapiens reticulon 4a protein.
Length = 1192
Score = 32.3 bits (70), Expect = 1.6
Identities = 17/46 (36%), Positives = 25/46 (54%)
Frame = +3
Query: 81 FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIE 218
+L L L G EN+ + SK+ + A TL I DLT+ S++E
Sbjct: 251 YLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE 296
>AC092461-1|AAX93116.1| 818|Homo sapiens unknown protein.
Length = 818
Score = 32.3 bits (70), Expect = 1.6
Identities = 17/46 (36%), Positives = 25/46 (54%)
Frame = +3
Query: 81 FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIE 218
+L L L G EN+ + SK+ + A TL I DLT+ S++E
Sbjct: 65 YLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE 110
>AB073359-1|BAE45717.1| 294|Homo sapiens NOGO-A protein.
Length = 294
Score = 32.3 bits (70), Expect = 1.6
Identities = 17/46 (36%), Positives = 25/46 (54%)
Frame = +3
Query: 81 FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIE 218
+L L L G EN+ + SK+ + A TL I DLT+ S++E
Sbjct: 50 YLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE 95
>AB040462-1|BAB18927.1| 1192|Homo sapiens RTN-xL protein.
Length = 1192
Score = 32.3 bits (70), Expect = 1.6
Identities = 17/46 (36%), Positives = 25/46 (54%)
Frame = +3
Query: 81 FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIE 218
+L L L G EN+ + SK+ + A TL I DLT+ S++E
Sbjct: 251 YLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE 296
>AB020693-1|BAA74909.2| 1233|Homo sapiens KIAA0886 protein protein.
Length = 1233
Score = 32.3 bits (70), Expect = 1.6
Identities = 17/46 (36%), Positives = 25/46 (54%)
Frame = +3
Query: 81 FLSKLGAQLSLTGRNVENLQKVSKDCDKFASTLSITADLTKESDIE 218
+L L L G EN+ + SK+ + A TL I DLT+ S++E
Sbjct: 292 YLGNLSTVLPTEGTLQENVSEASKEVSEKAKTLLIDRDLTEFSELE 337
>Z97054-9|CAI42651.1| 169|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 10 protein.
Length = 169
Score = 31.5 bits (68), Expect = 2.8
Identities = 18/69 (26%), Positives = 33/69 (47%), Gaps = 6/69 (8%)
Frame = +3
Query: 189 ADLTKESDIEKIIKKTIDHYGKLDVLVNNAGIIETGTIENT------SLAQYDRLMNTNV 350
AD+T E D++ + +G++DV VN AGI N +L + R+++ N+
Sbjct: 63 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 122
Query: 351 RSIYYLTML 377
+ + L
Sbjct: 123 MGTFNVIRL 131
>BC025724-1|AAH25724.1| 316|Homo sapiens retinol dehydrogenase 12
(all-trans/9-cis/11-cis) protein.
Length = 316
Score = 31.5 bits (68), Expect = 2.8
Identities = 19/45 (42%), Positives = 24/45 (53%)
Frame = +3
Query: 462 AYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGL 596
AY SK + FTR +A L GV V+PGV+ +EL R L
Sbjct: 199 AYCHSKLANVLFTRELAKRLQGTGVTTYAVHPGVVRSELVRHSSL 243
>AK054835-1|BAB70811.1| 316|Homo sapiens (ARSDR1) mRNA. protein.
Length = 316
Score = 31.5 bits (68), Expect = 2.8
Identities = 19/45 (42%), Positives = 24/45 (53%)
Frame = +3
Query: 462 AYNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTELQRRGGL 596
AY SK + FTR +A L GV V+PGV+ +EL R L
Sbjct: 199 AYCHSKLANVLFTRELAKRLQGTGVTTYAVHPGVVRSELVRHSSL 243
>BC112187-1|AAI12188.1| 181|Homo sapiens HSD11B1L protein protein.
Length = 181
Score = 30.7 bits (66), Expect = 5.0
Identities = 31/99 (31%), Positives = 41/99 (41%), Gaps = 1/99 (1%)
Frame = +3
Query: 249 GKLDVLV-NNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXX 425
G LD LV N+ G GT + A LM N S LT A+P L +SKG
Sbjct: 1 GGLDYLVLNHIGGAPAGTRARSPQATR-WLMQVNFVSYVQLTSRALPSLTDSKGSLVVVS 59
Query: 426 XXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRV 542
G Y+ +K ++D F + EL + V V
Sbjct: 60 SLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNV 98
>BC093950-1|AAH93950.1| 181|Homo sapiens HSD11B1L protein protein.
Length = 181
Score = 30.7 bits (66), Expect = 5.0
Identities = 31/99 (31%), Positives = 41/99 (41%), Gaps = 1/99 (1%)
Frame = +3
Query: 249 GKLDVLV-NNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXX 425
G LD LV N+ G GT + A LM N S LT A+P L +SKG
Sbjct: 1 GGLDYLVLNHIGGAPAGTRARSPQATR-WLMQVNFVSYVQLTSRALPSLTDSKGSLVVVS 59
Query: 426 XXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRV 542
G Y+ +K ++D F + EL + V V
Sbjct: 60 SLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNV 98
>AY313896-1|AAP83168.1| 234|Homo sapiens short-chain
dehydrogenase/reductase 10g protein.
Length = 234
Score = 30.7 bits (66), Expect = 5.0
Identities = 31/99 (31%), Positives = 41/99 (41%), Gaps = 1/99 (1%)
Frame = +3
Query: 249 GKLDVLV-NNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXX 425
G LD LV N+ G GT + A LM N S LT A+P L +SKG
Sbjct: 25 GGLDYLVLNHIGGAPAGTRARSPQATR-WLMQVNFVSYVQLTSRALPSLTDSKGSLVVVS 83
Query: 426 XXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRV 542
G Y+ +K ++D F + EL + V V
Sbjct: 84 SLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNV 122
>AY268351-1|AAP42285.1| 205|Homo sapiens short-chain
dehydrogenase/reductase 10a protein.
Length = 205
Score = 30.7 bits (66), Expect = 5.0
Identities = 31/99 (31%), Positives = 41/99 (41%), Gaps = 1/99 (1%)
Frame = +3
Query: 249 GKLDVLV-NNAGIIETGTIENTSLAQYDRLMNTNVRSIYYLTMLAVPHLLESKGXXXXXX 425
G LD LV N+ G GT + A LM N S LT A+P L +SKG
Sbjct: 25 GGLDYLVLNHIGGAPAGTRARSPQATR-WLMQVNFVSYVQLTSRALPSLTDSKGSLVVVS 83
Query: 426 XXXGIRSFPGVLAYNISKASVDQFTRCVALELAPKGVRV 542
G Y+ +K ++D F + EL + V V
Sbjct: 84 SLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNV 122
>AF240697-1|AAF82747.1| 172|Homo sapiens retinol dehydrogenase
homolog isoform-2 protein.
Length = 172
Score = 30.7 bits (66), Expect = 5.0
Identities = 14/38 (36%), Positives = 21/38 (55%)
Frame = +3
Query: 465 YNISKASVDQFTRCVALELAPKGVRVNCVNPGVILTEL 578
Y SK +V+ F + +L GV V+C+ PG+ T L
Sbjct: 29 YTPSKYAVEGFNDSLRRDLKAFGVHVSCIEPGLFKTNL 66
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 93,748,366
Number of Sequences: 237096
Number of extensions: 2001330
Number of successful extensions: 3614
Number of sequences better than 10.0: 228
Number of HSP's better than 10.0 without gapping: 3428
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3553
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 7647512560
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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