Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= bmmt27b09
(743 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC024202-1|AAH24202.1| 521|Homo sapiens karyopherin alpha 3 (im... 338 9e-93
BC017355-1|AAH17355.1| 521|Homo sapiens karyopherin alpha 3 (im... 338 9e-93
AL136301-1|CAH71145.1| 521|Homo sapiens karyopherin alpha 3 (im... 338 9e-93
AL135901-3|CAI40716.1| 521|Homo sapiens karyopherin alpha 3 (im... 338 9e-93
AK223480-1|BAD97200.1| 521|Homo sapiens karyopherin alpha 3 var... 338 9e-93
AF005263-1|AAQ13404.1| 521|Homo sapiens importin alpha-3 subuni... 338 9e-93
Y12394-1|CAA73026.1| 521|Homo sapiens SRP1-like protein protein. 338 1e-92
D89618-1|BAA20378.1| 521|Homo sapiens karyopherin alhph 3 protein. 338 1e-92
BC035090-1|AAH35090.1| 521|Homo sapiens karyopherin alpha 3 (im... 338 1e-92
AF034756-1|AAB87693.1| 521|Homo sapiens importin-alpha homolog ... 332 6e-91
U93240-1|AAC25605.1| 521|Homo sapiens importin alpha 3 protein. 327 2e-89
BC034493-1|AAH34493.1| 521|Homo sapiens karyopherin alpha 4 (im... 327 2e-89
BC028691-1|AAH28691.1| 521|Homo sapiens karyopherin alpha 4 (im... 327 2e-89
AB002533-1|BAA19546.1| 521|Homo sapiens Qip1 protein. 327 2e-89
U28386-1|AAA69957.1| 529|Homo sapiens hSRP1alpha protein. 246 7e-65
U09559-1|AAA65700.1| 529|Homo sapiens Rch1 protein. 246 7e-65
BC053343-1|AAH53343.1| 529|Homo sapiens karyopherin alpha 2 (RA... 246 7e-65
AJ303086-1|CAC83080.1| 529|Homo sapiens karyopherin alpha 2 pro... 246 7e-65
BT006665-1|AAP35311.1| 529|Homo sapiens karyopherin alpha 2 (RA... 246 9e-65
BC005978-1|AAH05978.1| 529|Homo sapiens karyopherin alpha 2 (RA... 246 9e-65
BC067848-1|AAH67848.1| 529|Homo sapiens karyopherin alpha 2 (RA... 240 4e-63
CR456743-1|CAG33024.1| 538|Homo sapiens KPNA1 protein. 207 4e-53
BT006959-1|AAP35605.1| 538|Homo sapiens karyopherin alpha 1 (im... 207 4e-53
BC090864-1|AAH90864.1| 538|Homo sapiens karyopherin alpha 1 (im... 207 4e-53
BC003009-1|AAH03009.1| 538|Homo sapiens karyopherin alpha 1 (im... 207 4e-53
BC002374-1|AAH02374.1| 538|Homo sapiens karyopherin alpha 1 (im... 207 4e-53
S75295-1|AAC60648.1| 538|Homo sapiens nucleoprotein interactor ... 204 3e-52
BT009843-1|AAP88845.1| 536|Homo sapiens karyopherin alpha 6 (im... 203 6e-52
BC020520-1|AAH20520.1| 536|Homo sapiens karyopherin alpha 6 (im... 203 6e-52
AL445248-5|CAH71948.1| 536|Homo sapiens karyopherin alpha 6 (im... 203 6e-52
AL049795-3|CAI22056.1| 536|Homo sapiens karyopherin alpha 6 (im... 203 6e-52
AF060543-1|AAC15233.1| 536|Homo sapiens importin alpha 7 subuni... 203 6e-52
AF005361-1|AAC51868.1| 536|Homo sapiens importin alpha 6 protein. 198 2e-50
BC047409-1|AAH47409.1| 539|Homo sapiens karyopherin alpha 5 (im... 197 3e-50
AL132795-5|CAI20500.1| 539|Homo sapiens karyopherin alpha 5 (im... 197 3e-50
AL049795-1|CAI22054.1| 321|Homo sapiens karyopherin alpha 6 (im... 83 1e-15
AL132795-6|CAI20501.1| 142|Homo sapiens karyopherin alpha 5 (im... 77 9e-14
Y12393-1|CAA73025.1| 281|Homo sapiens SRP1-like protein protein. 56 1e-07
BC030585-1|AAH30585.1| 458|Homo sapiens sperm associated antige... 52 2e-06
CR533552-1|CAG38583.1| 509|Homo sapiens SPAG6 protein. 50 7e-06
AL513128-4|CAH72210.1| 509|Homo sapiens sperm associated antige... 50 7e-06
AL513128-3|CAH72209.1| 458|Homo sapiens sperm associated antige... 50 7e-06
AL158211-15|CAI15963.1| 509|Homo sapiens sperm associated antig... 50 7e-06
AL158211-14|CAI15962.1| 458|Homo sapiens sperm associated antig... 50 7e-06
AF079363-1|AAC32590.1| 509|Homo sapiens sperm flagellar protein... 50 7e-06
AY217348-1|AAO45101.1| 725|Homo sapiens FLJ00019-like protein p... 42 0.003
AK024430-1|BAB15720.1| 732|Homo sapiens FLJ00019 protein protein. 41 0.004
X63465-1|CAA45067.1| 558|Homo sapiens smg GDS protein. 37 0.067
BC099845-1|AAH99845.1| 559|Homo sapiens RAP1GDS1 protein protein. 37 0.067
BC099708-1|AAH99708.1| 558|Homo sapiens RAP1GDS1 protein protein. 37 0.067
BC098334-1|AAH98334.1| 558|Homo sapiens RAP1GDS1 protein protein. 37 0.067
BC041699-1|AAH41699.1| 659|Homo sapiens armadillo repeat contai... 36 0.15
BC032661-1|AAH32661.1| 659|Homo sapiens armadillo repeat contai... 36 0.15
BC014945-1|AAH14945.1| 771|Homo sapiens ARMC5 protein protein. 36 0.15
AL513128-1|CAH72207.1| 246|Homo sapiens sperm associated antige... 36 0.15
AL158211-12|CAI15960.1| 246|Homo sapiens sperm associated antig... 36 0.15
AL096748-1|CAB46423.1| 242|Homo sapiens hypothetical protein pr... 36 0.15
AK023125-1|BAB14418.1| 502|Homo sapiens protein ( Homo sapiens ... 36 0.15
AK001882-1|BAA91959.1| 431|Homo sapiens protein ( Homo sapiens ... 34 0.62
BC011728-1|AAH11728.1| 198|Homo sapiens armadillo repeat contai... 33 0.82
AL513128-2|CAH72208.1| 191|Homo sapiens sperm associated antige... 33 0.82
AL158211-13|CAI15961.1| 191|Homo sapiens sperm associated antig... 33 0.82
AK025813-1|BAB15242.1| 198|Homo sapiens protein ( Homo sapiens ... 33 0.82
BC039312-1|AAH39312.1| 872|Homo sapiens armadillo repeat contai... 33 1.1
AY436643-1|AAR99738.1| 688|Homo sapiens beta-catenin-like prote... 33 1.1
AL139815-2|CAH72189.1| 875|Homo sapiens novel protein protein. 33 1.1
AL139815-1|CAH72188.1| 546|Homo sapiens novel protein protein. 33 1.1
AK057389-1|BAB71463.1| 669|Homo sapiens protein ( Homo sapiens ... 33 1.1
D50550-1|BAA19516.1| 1032|Homo sapiens LLGL protein. 33 1.4
Z83131-1|CAI42019.1| 632|Homo sapiens armadillo repeat containi... 32 2.5
BC015926-1|AAH15926.1| 632|Homo sapiens ARMCX2 protein protein. 32 2.5
BC012541-1|AAH12541.1| 632|Homo sapiens armadillo repeat contai... 32 2.5
BC009618-1|AAH09618.1| 253|Homo sapiens TMCO6 protein protein. 32 2.5
BC001910-1|AAH01910.1| 253|Homo sapiens TMCO6 protein protein. 32 2.5
AB011084-1|BAA25438.2| 710|Homo sapiens KIAA0512 protein protein. 32 2.5
BC132827-1|AAI32828.1| 949|Homo sapiens CCDC66 protein protein. 31 3.3
BC047509-1|AAH47509.1| 831|Homo sapiens coiled-coil domain cont... 31 3.3
AY376900-1|AAQ85126.1| 516|Homo sapiens GTP-GDP dissociation st... 31 4.4
Z19054-1|CAA79497.1| 781|Homo sapiens beta catenin protein. 31 5.8
X87838-1|CAA61107.1| 781|Homo sapiens beta-catenin protein. 31 5.8
U72069-1|AAB58254.1| 890|Homo sapiens karyopherin beta2 protein. 31 5.8
U70322-1|AAC50723.1| 890|Homo sapiens transportin protein. 31 5.8
BC058926-1|AAH58926.1| 781|Homo sapiens catenin (cadherin-assoc... 31 5.8
BC040340-1|AAH40340.1| 890|Homo sapiens transportin 1 protein. 31 5.8
AY463360-1|AAR18817.1| 781|Homo sapiens catenin (cadherin-assoc... 31 5.8
AB062292-1|BAB93475.1| 511|Homo sapiens catenin beta 1 protein. 31 5.8
BC117686-1|AAI17687.1| 1683|Homo sapiens SHPRH protein protein. 30 7.6
BC117685-1|AAI17686.1| 155|Homo sapiens SHPRH protein protein. 30 7.6
BC113089-1|AAI13090.1| 155|Homo sapiens SHPRH protein protein. 30 7.6
AY163808-1|AAO06907.1| 1659|Homo sapiens helicase-like protein p... 30 7.6
AY161136-1|AAO26201.1| 1683|Homo sapiens SNF2 histone linker PHD... 30 7.6
AL451145-1|CAH70765.1| 1683|Homo sapiens SNF2 histone linker PHD... 30 7.6
AL356599-2|CAI41120.1| 1683|Homo sapiens SNF2 histone linker PHD... 30 7.6
AK075318-1|BAC11544.1| 584|Homo sapiens protein ( Homo sapiens ... 30 7.6
>BC024202-1|AAH24202.1| 521|Homo sapiens karyopherin alpha 3
(importin alpha 4) protein.
Length = 521
Score = 338 bits (832), Expect = 9e-93
Identities = 159/238 (66%), Positives = 192/238 (80%), Gaps = 1/238 (0%)
Frame = +2
Query: 14 NRMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYSTDEEEIDKNLATT 193
+R+ FKN G+DV+ MRR RNEVTVELRKNKR+E L K+RNVP S ++ ++D +
Sbjct: 10 HRIKSFKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNVPQEESLEDSDVDADFKAQ 69
Query: 194 DLD-ELVMNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNP 370
++ E ++ A ++NP QL+AVQ RKLLS D+NPPID+LI +GILPILV+CL R DNP
Sbjct: 70 NVTLEAILQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNP 129
Query: 371 ALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGP 550
+LQFE AWALTNIASGTSAQT VV + AVP+FL+LL SPH+NVC+QAVWALGNIIGDGP
Sbjct: 130 SLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGP 189
Query: 551 VLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNLCRSKDPPPPLKTIQEILPGL 724
RD+VI LGVVKPLLS I IPI FLRNVTWVIVNLCR+KDPPPP++T+QEILP L
Sbjct: 190 QCRDYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPAL 247
Score = 57.2 bits (132), Expect = 6e-08
Identities = 39/125 (31%), Positives = 58/125 (46%), Gaps = 1/125 (0%)
Frame = +2
Query: 293 NPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFL 472
N I +I +G++P LV LS + +Q A+ NI +GT QT V++ + F
Sbjct: 274 NEQIQMVIDSGVVPFLVPLLSHQE-VKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFP 332
Query: 473 QLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLL-SLIKSDIPIPFLRNVTW 649
LL P E + +AVW L NI VI+ G++ ++ L K D + W
Sbjct: 333 NLLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQ--KEAAW 390
Query: 650 VIVNL 664
I NL
Sbjct: 391 AISNL 395
Score = 31.1 bits (67), Expect = 4.4
Identities = 22/101 (21%), Positives = 38/101 (37%)
Frame = +2
Query: 305 DELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLM 484
D +I+ G++ L+ +S + W + N+ +P L+
Sbjct: 193 DYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPALCVLIY 252
Query: 485 SPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLI 607
N+ VWAL + G VI+ GVV L+ L+
Sbjct: 253 HTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLL 293
>BC017355-1|AAH17355.1| 521|Homo sapiens karyopherin alpha 3
(importin alpha 4) protein.
Length = 521
Score = 338 bits (832), Expect = 9e-93
Identities = 159/238 (66%), Positives = 192/238 (80%), Gaps = 1/238 (0%)
Frame = +2
Query: 14 NRMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYSTDEEEIDKNLATT 193
+R+ FKN G+DV+ MRR RNEVTVELRKNKR+E L K+RNVP S ++ ++D +
Sbjct: 10 HRIKSFKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNVPQEESLEDSDVDADFKAQ 69
Query: 194 DLD-ELVMNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNP 370
++ E ++ A ++NP QL+AVQ RKLLS D+NPPID+LI +GILPILV+CL R DNP
Sbjct: 70 NVTLEAILQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNP 129
Query: 371 ALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGP 550
+LQFE AWALTNIASGTSAQT VV + AVP+FL+LL SPH+NVC+QAVWALGNIIGDGP
Sbjct: 130 SLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGP 189
Query: 551 VLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNLCRSKDPPPPLKTIQEILPGL 724
RD+VI LGVVKPLLS I IPI FLRNVTWVIVNLCR+KDPPPP++T+QEILP L
Sbjct: 190 QCRDYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPAL 247
Score = 57.2 bits (132), Expect = 6e-08
Identities = 39/125 (31%), Positives = 58/125 (46%), Gaps = 1/125 (0%)
Frame = +2
Query: 293 NPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFL 472
N I +I +G++P LV LS + +Q A+ NI +GT QT V++ + F
Sbjct: 274 NEQIQMVIDSGVVPFLVPLLSHQE-VKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFP 332
Query: 473 QLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLL-SLIKSDIPIPFLRNVTW 649
LL P E + +AVW L NI VI+ G++ ++ L K D + W
Sbjct: 333 NLLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQ--KEAAW 390
Query: 650 VIVNL 664
I NL
Sbjct: 391 AISNL 395
Score = 31.1 bits (67), Expect = 4.4
Identities = 22/101 (21%), Positives = 38/101 (37%)
Frame = +2
Query: 305 DELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLM 484
D +I+ G++ L+ +S + W + N+ +P L+
Sbjct: 193 DYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPALCVLIY 252
Query: 485 SPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLI 607
N+ VWAL + G VI+ GVV L+ L+
Sbjct: 253 HTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLL 293
>AL136301-1|CAH71145.1| 521|Homo sapiens karyopherin alpha 3
(importin alpha 4) protein.
Length = 521
Score = 338 bits (832), Expect = 9e-93
Identities = 159/238 (66%), Positives = 192/238 (80%), Gaps = 1/238 (0%)
Frame = +2
Query: 14 NRMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYSTDEEEIDKNLATT 193
+R+ FKN G+DV+ MRR RNEVTVELRKNKR+E L K+RNVP S ++ ++D +
Sbjct: 10 HRIKSFKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNVPQEESLEDSDVDADFKAQ 69
Query: 194 DLD-ELVMNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNP 370
++ E ++ A ++NP QL+AVQ RKLLS D+NPPID+LI +GILPILV+CL R DNP
Sbjct: 70 NVTLEAILQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNP 129
Query: 371 ALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGP 550
+LQFE AWALTNIASGTSAQT VV + AVP+FL+LL SPH+NVC+QAVWALGNIIGDGP
Sbjct: 130 SLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGP 189
Query: 551 VLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNLCRSKDPPPPLKTIQEILPGL 724
RD+VI LGVVKPLLS I IPI FLRNVTWVIVNLCR+KDPPPP++T+QEILP L
Sbjct: 190 QCRDYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPAL 247
Score = 57.2 bits (132), Expect = 6e-08
Identities = 39/125 (31%), Positives = 58/125 (46%), Gaps = 1/125 (0%)
Frame = +2
Query: 293 NPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFL 472
N I +I +G++P LV LS + +Q A+ NI +GT QT V++ + F
Sbjct: 274 NEQIQMVIDSGVVPFLVPLLSHQE-VKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFP 332
Query: 473 QLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLL-SLIKSDIPIPFLRNVTW 649
LL P E + +AVW L NI VI+ G++ ++ L K D + W
Sbjct: 333 NLLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQ--KEAAW 390
Query: 650 VIVNL 664
I NL
Sbjct: 391 AISNL 395
Score = 31.1 bits (67), Expect = 4.4
Identities = 22/101 (21%), Positives = 38/101 (37%)
Frame = +2
Query: 305 DELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLM 484
D +I+ G++ L+ +S + W + N+ +P L+
Sbjct: 193 DYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPALCVLIY 252
Query: 485 SPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLI 607
N+ VWAL + G VI+ GVV L+ L+
Sbjct: 253 HTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLL 293
>AL135901-3|CAI40716.1| 521|Homo sapiens karyopherin alpha 3
(importin alpha 4) protein.
Length = 521
Score = 338 bits (832), Expect = 9e-93
Identities = 159/238 (66%), Positives = 192/238 (80%), Gaps = 1/238 (0%)
Frame = +2
Query: 14 NRMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYSTDEEEIDKNLATT 193
+R+ FKN G+DV+ MRR RNEVTVELRKNKR+E L K+RNVP S ++ ++D +
Sbjct: 10 HRIKSFKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNVPQEESLEDSDVDADFKAQ 69
Query: 194 DLD-ELVMNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNP 370
++ E ++ A ++NP QL+AVQ RKLLS D+NPPID+LI +GILPILV+CL R DNP
Sbjct: 70 NVTLEAILQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNP 129
Query: 371 ALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGP 550
+LQFE AWALTNIASGTSAQT VV + AVP+FL+LL SPH+NVC+QAVWALGNIIGDGP
Sbjct: 130 SLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGP 189
Query: 551 VLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNLCRSKDPPPPLKTIQEILPGL 724
RD+VI LGVVKPLLS I IPI FLRNVTWVIVNLCR+KDPPPP++T+QEILP L
Sbjct: 190 QCRDYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPAL 247
Score = 57.2 bits (132), Expect = 6e-08
Identities = 39/125 (31%), Positives = 58/125 (46%), Gaps = 1/125 (0%)
Frame = +2
Query: 293 NPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFL 472
N I +I +G++P LV LS + +Q A+ NI +GT QT V++ + F
Sbjct: 274 NEQIQMVIDSGVVPFLVPLLSHQE-VKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFP 332
Query: 473 QLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLL-SLIKSDIPIPFLRNVTW 649
LL P E + +AVW L NI VI+ G++ ++ L K D + W
Sbjct: 333 NLLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQ--KEAAW 390
Query: 650 VIVNL 664
I NL
Sbjct: 391 AISNL 395
Score = 31.1 bits (67), Expect = 4.4
Identities = 22/101 (21%), Positives = 38/101 (37%)
Frame = +2
Query: 305 DELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLM 484
D +I+ G++ L+ +S + W + N+ +P L+
Sbjct: 193 DYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPALCVLIY 252
Query: 485 SPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLI 607
N+ VWAL + G VI+ GVV L+ L+
Sbjct: 253 HTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLL 293
>AK223480-1|BAD97200.1| 521|Homo sapiens karyopherin alpha 3
variant protein.
Length = 521
Score = 338 bits (832), Expect = 9e-93
Identities = 159/238 (66%), Positives = 192/238 (80%), Gaps = 1/238 (0%)
Frame = +2
Query: 14 NRMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYSTDEEEIDKNLATT 193
+R+ FKN G+DV+ MRR RNEVTVELRKNKR+E L K+RNVP S ++ ++D +
Sbjct: 10 HRIKSFKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNVPQEKSLEDSDVDADFKAQ 69
Query: 194 DLD-ELVMNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNP 370
++ E ++ A ++NP QL+AVQ RKLLS D+NPPID+LI +GILPILV+CL R DNP
Sbjct: 70 NVTLEAILQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNP 129
Query: 371 ALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGP 550
+LQFE AWALTNIASGTSAQT VV + AVP+FL+LL SPH+NVC+QAVWALGNIIGDGP
Sbjct: 130 SLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGP 189
Query: 551 VLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNLCRSKDPPPPLKTIQEILPGL 724
RD+VI LGVVKPLLS I IPI FLRNVTWVIVNLCR+KDPPPP++T+QEILP L
Sbjct: 190 QCRDYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPAL 247
Score = 54.0 bits (124), Expect = 5e-07
Identities = 35/109 (32%), Positives = 53/109 (48%), Gaps = 1/109 (0%)
Frame = +2
Query: 293 NPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFL 472
N I +I +G++P LV LS + +Q A+ NI +GT QT V++ + F
Sbjct: 274 NEQIQMVIDSGVVPFLVPLLSHQE-VKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFP 332
Query: 473 QLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLL-SLIKSD 616
LL P E + +AVW L NI VI+ G++ ++ L K D
Sbjct: 333 NLLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMIIHQLAKGD 381
Score = 31.1 bits (67), Expect = 4.4
Identities = 22/101 (21%), Positives = 38/101 (37%)
Frame = +2
Query: 305 DELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLM 484
D +I+ G++ L+ +S + W + N+ +P L+
Sbjct: 193 DYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPALCVLIY 252
Query: 485 SPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLI 607
N+ VWAL + G VI+ GVV L+ L+
Sbjct: 253 HTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLL 293
>AF005263-1|AAQ13404.1| 521|Homo sapiens importin alpha-3 subunit
protein.
Length = 521
Score = 338 bits (832), Expect = 9e-93
Identities = 159/238 (66%), Positives = 192/238 (80%), Gaps = 1/238 (0%)
Frame = +2
Query: 14 NRMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYSTDEEEIDKNLATT 193
+R+ FKN G+DV+ MRR RNEVTVELRKNKR+E L K+RNVP S ++ ++D +
Sbjct: 10 HRIKSFKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNVPQEESLEDSDVDADFKAQ 69
Query: 194 DLD-ELVMNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNP 370
++ E ++ A ++NP QL+AVQ RKLLS D+NPPID+LI +GILPILV+CL R DNP
Sbjct: 70 NVTLEAILQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNP 129
Query: 371 ALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGP 550
+LQFE AWALTNIASGTSAQT VV + AVP+FL+LL SPH+NVC+QAVWALGNIIGDGP
Sbjct: 130 SLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGP 189
Query: 551 VLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNLCRSKDPPPPLKTIQEILPGL 724
RD+VI LGVVKPLLS I IPI FLRNVTWVIVNLCR+KDPPPP++T+QEILP L
Sbjct: 190 QCRDYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPAL 247
Score = 57.2 bits (132), Expect = 6e-08
Identities = 39/125 (31%), Positives = 58/125 (46%), Gaps = 1/125 (0%)
Frame = +2
Query: 293 NPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFL 472
N I +I +G++P LV LS + +Q A+ NI +GT QT V++ + F
Sbjct: 274 NEQIQMVIDSGVVPFLVPLLSHQE-VKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFP 332
Query: 473 QLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLL-SLIKSDIPIPFLRNVTW 649
LL P E + +AVW L NI VI+ G++ ++ L K D + W
Sbjct: 333 NLLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQ--KEAAW 390
Query: 650 VIVNL 664
I NL
Sbjct: 391 AISNL 395
Score = 31.1 bits (67), Expect = 4.4
Identities = 22/101 (21%), Positives = 38/101 (37%)
Frame = +2
Query: 305 DELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLM 484
D +I+ G++ L+ +S + W + N+ +P L+
Sbjct: 193 DYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPALCVLIY 252
Query: 485 SPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLI 607
N+ VWAL + G VI+ GVV L+ L+
Sbjct: 253 HTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLL 293
>Y12394-1|CAA73026.1| 521|Homo sapiens SRP1-like protein protein.
Length = 521
Score = 338 bits (831), Expect = 1e-92
Identities = 159/238 (66%), Positives = 192/238 (80%), Gaps = 1/238 (0%)
Frame = +2
Query: 14 NRMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYSTDEEEIDKNLATT 193
+R+ FKN G+DV+ MRR RNEVT+ELRKNKR+E L K+RNVP S ++ ++D +
Sbjct: 10 HRIKSFKNKGRDVETMRRHRNEVTMELRKNKRDEHLLKKRNVPQEESLEDSDVDADFKAQ 69
Query: 194 DLD-ELVMNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNP 370
++ E ++ A ++NP QL+AVQ RKLLS D+NPPID+LI +GILPILV+CL R DNP
Sbjct: 70 NVTLEAILQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNP 129
Query: 371 ALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGP 550
+LQFE AWALTNIASGTSAQT VV + AVP+FL+LL SPH+NVC+QAVWALGNIIGDGP
Sbjct: 130 SLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGP 189
Query: 551 VLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNLCRSKDPPPPLKTIQEILPGL 724
RD+VI LGVVKPLLS I IPI FLRNVTWVIVNLCR+KDPPPPL+T+QEILP L
Sbjct: 190 QCRDYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPLETVQEILPAL 247
Score = 57.2 bits (132), Expect = 6e-08
Identities = 39/125 (31%), Positives = 58/125 (46%), Gaps = 1/125 (0%)
Frame = +2
Query: 293 NPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFL 472
N I +I +G++P LV LS + +Q A+ NI +GT QT V++ + F
Sbjct: 274 NEQIQMVIDSGVVPFLVPLLSHQE-VKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFP 332
Query: 473 QLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLL-SLIKSDIPIPFLRNVTW 649
LL P E + +AVW L NI VI+ G++ ++ L K D + W
Sbjct: 333 NLLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQ--KEAAW 390
Query: 650 VIVNL 664
I NL
Sbjct: 391 AISNL 395
Score = 31.1 bits (67), Expect = 4.4
Identities = 22/101 (21%), Positives = 38/101 (37%)
Frame = +2
Query: 305 DELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLM 484
D +I+ G++ L+ +S + W + N+ +P L+
Sbjct: 193 DYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPLETVQEILPALCVLIY 252
Query: 485 SPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLI 607
N+ VWAL + G VI+ GVV L+ L+
Sbjct: 253 HTDVNIVVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLL 293
>D89618-1|BAA20378.1| 521|Homo sapiens karyopherin alhph 3 protein.
Length = 521
Score = 338 bits (831), Expect = 1e-92
Identities = 159/238 (66%), Positives = 192/238 (80%), Gaps = 1/238 (0%)
Frame = +2
Query: 14 NRMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYSTDEEEIDKNLATT 193
+R+ FKN G+DV+ MRR RNEVTVELRKNKR+E L K+RNVP S ++ ++D +
Sbjct: 10 HRIKSFKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNVPQEESLEDSDVDADFKAQ 69
Query: 194 DLD-ELVMNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNP 370
++ E ++ A ++NP QL+AVQ RKLLS D+NPPID+LI +GILPILV+CL R DNP
Sbjct: 70 NVTLEAILQNATSDNPVVQLSAVQAARKLLSSDQNPPIDDLIKSGILPILVKCLERDDNP 129
Query: 371 ALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGP 550
+LQFE AWALTNIASGTSAQT VV + AVP+FL+LL SPH+NVC+QAVWALGNIIGDGP
Sbjct: 130 SLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGP 189
Query: 551 VLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNLCRSKDPPPPLKTIQEILPGL 724
RD+VI LGVVKPLLS I IPI FLRNVTWVIVNLCR+KDPPPP++T+QEILP L
Sbjct: 190 QCRDYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPAL 247
Score = 57.2 bits (132), Expect = 6e-08
Identities = 39/125 (31%), Positives = 58/125 (46%), Gaps = 1/125 (0%)
Frame = +2
Query: 293 NPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFL 472
N I +I +G++P LV LS + +Q A+ NI +GT QT V++ + F
Sbjct: 274 NEQIQMVIDSGVVPFLVPLLSHQE-VKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFP 332
Query: 473 QLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLL-SLIKSDIPIPFLRNVTW 649
LL P E + +AVW L NI VI+ G++ ++ L K D + W
Sbjct: 333 NLLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQ--KEAAW 390
Query: 650 VIVNL 664
I NL
Sbjct: 391 AISNL 395
Score = 31.1 bits (67), Expect = 4.4
Identities = 22/101 (21%), Positives = 38/101 (37%)
Frame = +2
Query: 305 DELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLM 484
D +I+ G++ L+ +S + W + N+ +P L+
Sbjct: 193 DYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPALCVLIY 252
Query: 485 SPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLI 607
N+ VWAL + G VI+ GVV L+ L+
Sbjct: 253 HTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLL 293
>BC035090-1|AAH35090.1| 521|Homo sapiens karyopherin alpha 3
(importin alpha 4) protein.
Length = 521
Score = 338 bits (831), Expect = 1e-92
Identities = 158/238 (66%), Positives = 192/238 (80%), Gaps = 1/238 (0%)
Frame = +2
Query: 14 NRMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYSTDEEEIDKNLATT 193
+R+ FKN G+DV+ MRR RNEVTVELRKNKR+E L K+RNVP S ++ ++D +
Sbjct: 10 HRIKSFKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNVPQEESLEDSDVDADFKAQ 69
Query: 194 DLD-ELVMNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNP 370
++ E ++ A ++NP QL+AVQ RKLLS D+NPPID+LI +GILPILV+CL R DNP
Sbjct: 70 NVTLEAILQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNP 129
Query: 371 ALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGP 550
+LQFE AWALTNIASGTSAQT +V + AVP+FL+LL SPH+NVC+QAVWALGNIIGDGP
Sbjct: 130 SLQFEAAWALTNIASGTSAQTQDIVQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGP 189
Query: 551 VLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNLCRSKDPPPPLKTIQEILPGL 724
RD+VI LGVVKPLLS I IPI FLRNVTWVIVNLCR+KDPPPP++T+QEILP L
Sbjct: 190 QCRDYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPAL 247
Score = 57.6 bits (133), Expect = 4e-08
Identities = 39/125 (31%), Positives = 58/125 (46%), Gaps = 1/125 (0%)
Frame = +2
Query: 293 NPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFL 472
N I +I +G++P LV LS + +Q A+ NI +GT QT V++ + F
Sbjct: 274 NEQIQMVIDSGVVPFLVPLLSHQE-VKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFQ 332
Query: 473 QLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLL-SLIKSDIPIPFLRNVTW 649
LL P E + +AVW L NI VI+ G++ ++ L K D + W
Sbjct: 333 NLLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQ--KEAAW 390
Query: 650 VIVNL 664
I NL
Sbjct: 391 AISNL 395
Score = 31.1 bits (67), Expect = 4.4
Identities = 22/101 (21%), Positives = 38/101 (37%)
Frame = +2
Query: 305 DELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLM 484
D +I+ G++ L+ +S + W + N+ +P L+
Sbjct: 193 DYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETVQEILPALCVLIY 252
Query: 485 SPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLI 607
N+ VWAL + G VI+ GVV L+ L+
Sbjct: 253 HTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLL 293
>AF034756-1|AAB87693.1| 521|Homo sapiens importin-alpha homolog
protein.
Length = 521
Score = 332 bits (817), Expect = 6e-91
Identities = 157/238 (65%), Positives = 190/238 (79%), Gaps = 1/238 (0%)
Frame = +2
Query: 14 NRMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYSTDEEEIDKNLATT 193
+R+ FKN G+DV+ MRR RNEVTVELRKNKR+E L K+RNVP S ++ ++D +
Sbjct: 10 HRIKSFKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNVPQEESLEDSDVDADFKAQ 69
Query: 194 DLD-ELVMNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNP 370
++ E ++ A ++NP QL+AVQ RKLLS D+NPPID+LI +GILPILV+CL R DNP
Sbjct: 70 NVTLEAILQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNP 129
Query: 371 ALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGP 550
+LQFE AWALTNIASGTSAQT V + AVP+FL+LL SPH+NVC+QAVWALGNIIGDGP
Sbjct: 130 SLQFEAAWALTNIASGTSAQTQAVGQSNAVPLFLRLLRSPHQNVCEQAVWALGNIIGDGP 189
Query: 551 VLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNLCRSKDPPPPLKTIQEILPGL 724
RD+VI LGVVKPLLS I IPI FLRNVTWVIVNLCR+KDPPP ++T+QEILP L
Sbjct: 190 QCRDYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPTMETVQEILPAL 247
Score = 57.2 bits (132), Expect = 6e-08
Identities = 39/125 (31%), Positives = 58/125 (46%), Gaps = 1/125 (0%)
Frame = +2
Query: 293 NPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFL 472
N I +I +G++P LV LS + +Q A+ NI +GT QT V++ + F
Sbjct: 274 NEQIQMVIDSGVVPFLVPLLSHQE-VKVQTAALRAVGNIVTGTDEQTQVVLNCDVLSHFP 332
Query: 473 QLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLL-SLIKSDIPIPFLRNVTW 649
LL P E + +AVW L NI VI+ G++ ++ L K D + W
Sbjct: 333 NLLSHPKEKINKEAVWFLSNITAGNQQQVQAVIDAGLIPMIIHQLAKGDFGTQ--KEAAW 390
Query: 650 VIVNL 664
I NL
Sbjct: 391 AISNL 395
Score = 31.9 bits (69), Expect = 2.5
Identities = 22/101 (21%), Positives = 38/101 (37%)
Frame = +2
Query: 305 DELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLM 484
D +I+ G++ L+ +S + W + N+ +P L+
Sbjct: 193 DYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPTMETVQEILPALCVLIY 252
Query: 485 SPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLI 607
N+ VWAL + G VI+ GVV L+ L+
Sbjct: 253 HTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLL 293
>U93240-1|AAC25605.1| 521|Homo sapiens importin alpha 3 protein.
Length = 521
Score = 327 bits (804), Expect = 2e-89
Identities = 159/238 (66%), Positives = 189/238 (79%), Gaps = 2/238 (0%)
Frame = +2
Query: 17 RMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYSTDEEEIDKN--LAT 190
R+ FKN G+D++ MRR+RNEV VELRKNKR+E L KRRNVP ++ +ID + +
Sbjct: 11 RLKNFKNKGRDLETMRRQRNEVVVELRKNKRDEHLLKRRNVPHEDICEDSDIDGDYRVQN 70
Query: 191 TDLDELVMNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNP 370
T L+ +V NA++ +N QL+AVQ RKLLS D+NPPID+LI +GILPILV CL R DNP
Sbjct: 71 TSLEAIVQNASS-DNQGIQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVHCLERDDNP 129
Query: 371 ALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGP 550
+LQFE AWALTNIASGTS QT VV + AVP+FL+LL SPH+NVC+QAVWALGNIIGDGP
Sbjct: 130 SLQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGP 189
Query: 551 VLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNLCRSKDPPPPLKTIQEILPGL 724
RD+VI LGVVKPLLS I IPI FLRNVTWV+VNLCR KDPPPP++TIQEILP L
Sbjct: 190 QCRDYVISLGVVKPLLSFISPSIPITFLRNVTWVMVNLCRHKDPPPPMETIQEILPAL 247
Score = 56.4 bits (130), Expect = 1e-07
Identities = 41/125 (32%), Positives = 59/125 (47%), Gaps = 1/125 (0%)
Frame = +2
Query: 293 NPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFL 472
N I +I +GI+P LV LS + +Q A+ NI +GT QT V++ A+ F
Sbjct: 274 NEQIQMVIDSGIVPHLVPLLSHQE-VKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFP 332
Query: 473 QLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLI-KSDIPIPFLRNVTW 649
LL P E + +AVW L NI VI+ +V ++ L+ K D + W
Sbjct: 333 ALLTHPKEKINKEAVWFLSNITAGNQQQVQAVIDANLVPMIIHLLDKGDFGTQ--KEAAW 390
Query: 650 VIVNL 664
I NL
Sbjct: 391 AISNL 395
Score = 42.7 bits (96), Expect = 0.001
Identities = 22/76 (28%), Positives = 37/76 (48%), Gaps = 1/76 (1%)
Frame = +2
Query: 383 ETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLR- 559
E W L+NI +G Q V+ A VP+ + LL +A WA+ N+ G +
Sbjct: 345 EAVWFLSNITAGNQQQVQAVIDANLVPMIIHLLDKGDFGTQKEAAWAISNLTISGRKDQV 404
Query: 560 DFVIELGVVKPLLSLI 607
++I+ V+ P +L+
Sbjct: 405 AYLIQQNVIPPFCNLL 420
Score = 30.3 bits (65), Expect = 7.6
Identities = 21/101 (20%), Positives = 38/101 (37%)
Frame = +2
Query: 305 DELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLM 484
D +I+ G++ L+ +S + W + N+ +P L+
Sbjct: 193 DYVISLGVVKPLLSFISPSIPITFLRNVTWVMVNLCRHKDPPPPMETIQEILPALCVLIH 252
Query: 485 SPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLI 607
N+ VWAL + G VI+ G+V L+ L+
Sbjct: 253 HTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLL 293
>BC034493-1|AAH34493.1| 521|Homo sapiens karyopherin alpha 4
(importin alpha 3) protein.
Length = 521
Score = 327 bits (804), Expect = 2e-89
Identities = 159/238 (66%), Positives = 189/238 (79%), Gaps = 2/238 (0%)
Frame = +2
Query: 17 RMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYSTDEEEIDKN--LAT 190
R+ FKN G+D++ MRR+RNEV VELRKNKR+E L KRRNVP ++ +ID + +
Sbjct: 11 RLKNFKNKGRDLETMRRQRNEVVVELRKNKRDEHLLKRRNVPHEDICEDSDIDGDYRVQN 70
Query: 191 TDLDELVMNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNP 370
T L+ +V NA++ +N QL+AVQ RKLLS D+NPPID+LI +GILPILV CL R DNP
Sbjct: 71 TSLEAIVQNASS-DNQGIQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVHCLERDDNP 129
Query: 371 ALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGP 550
+LQFE AWALTNIASGTS QT VV + AVP+FL+LL SPH+NVC+QAVWALGNIIGDGP
Sbjct: 130 SLQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGP 189
Query: 551 VLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNLCRSKDPPPPLKTIQEILPGL 724
RD+VI LGVVKPLLS I IPI FLRNVTWV+VNLCR KDPPPP++TIQEILP L
Sbjct: 190 QCRDYVISLGVVKPLLSFISPSIPITFLRNVTWVMVNLCRHKDPPPPMETIQEILPAL 247
Score = 56.4 bits (130), Expect = 1e-07
Identities = 41/125 (32%), Positives = 59/125 (47%), Gaps = 1/125 (0%)
Frame = +2
Query: 293 NPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFL 472
N I +I +GI+P LV LS + +Q A+ NI +GT QT V++ A+ F
Sbjct: 274 NEQIQMVIDSGIVPHLVPLLSHQE-VKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFP 332
Query: 473 QLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLI-KSDIPIPFLRNVTW 649
LL P E + +AVW L NI VI+ +V ++ L+ K D + W
Sbjct: 333 ALLTHPKEKINKEAVWFLSNITAGNQQQVQAVIDANLVPMIIHLLDKGDFGTQ--KEAAW 390
Query: 650 VIVNL 664
I NL
Sbjct: 391 AISNL 395
Score = 42.7 bits (96), Expect = 0.001
Identities = 22/76 (28%), Positives = 37/76 (48%), Gaps = 1/76 (1%)
Frame = +2
Query: 383 ETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLR- 559
E W L+NI +G Q V+ A VP+ + LL +A WA+ N+ G +
Sbjct: 345 EAVWFLSNITAGNQQQVQAVIDANLVPMIIHLLDKGDFGTQKEAAWAISNLTISGRKDQV 404
Query: 560 DFVIELGVVKPLLSLI 607
++I+ V+ P +L+
Sbjct: 405 AYLIQQNVIPPFCNLL 420
Score = 30.3 bits (65), Expect = 7.6
Identities = 21/101 (20%), Positives = 38/101 (37%)
Frame = +2
Query: 305 DELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLM 484
D +I+ G++ L+ +S + W + N+ +P L+
Sbjct: 193 DYVISLGVVKPLLSFISPSIPITFLRNVTWVMVNLCRHKDPPPPMETIQEILPALCVLIH 252
Query: 485 SPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLI 607
N+ VWAL + G VI+ G+V L+ L+
Sbjct: 253 HTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLL 293
>BC028691-1|AAH28691.1| 521|Homo sapiens karyopherin alpha 4
(importin alpha 3) protein.
Length = 521
Score = 327 bits (804), Expect = 2e-89
Identities = 159/238 (66%), Positives = 189/238 (79%), Gaps = 2/238 (0%)
Frame = +2
Query: 17 RMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYSTDEEEIDKN--LAT 190
R+ FKN G+D++ MRR+RNEV VELRKNKR+E L KRRNVP ++ +ID + +
Sbjct: 11 RLKNFKNKGRDLETMRRQRNEVVVELRKNKRDEHLLKRRNVPHEDICEDSDIDGDYRVQN 70
Query: 191 TDLDELVMNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNP 370
T L+ +V NA++ +N QL+AVQ RKLLS D+NPPID+LI +GILPILV CL R DNP
Sbjct: 71 TSLEAIVQNASS-DNQGIQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVHCLERDDNP 129
Query: 371 ALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGP 550
+LQFE AWALTNIASGTS QT VV + AVP+FL+LL SPH+NVC+QAVWALGNIIGDGP
Sbjct: 130 SLQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGP 189
Query: 551 VLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNLCRSKDPPPPLKTIQEILPGL 724
RD+VI LGVVKPLLS I IPI FLRNVTWV+VNLCR KDPPPP++TIQEILP L
Sbjct: 190 QCRDYVISLGVVKPLLSFISPSIPITFLRNVTWVMVNLCRHKDPPPPMETIQEILPAL 247
Score = 56.4 bits (130), Expect = 1e-07
Identities = 41/125 (32%), Positives = 59/125 (47%), Gaps = 1/125 (0%)
Frame = +2
Query: 293 NPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFL 472
N I +I +GI+P LV LS + +Q A+ NI +GT QT V++ A+ F
Sbjct: 274 NEQIQMVIDSGIVPHLVPLLSHQE-VKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFP 332
Query: 473 QLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLI-KSDIPIPFLRNVTW 649
LL P E + +AVW L NI VI+ +V ++ L+ K D + W
Sbjct: 333 ALLTHPKEKINKEAVWFLSNITAGNQQQVQAVIDANLVPMIIHLLDKGDFGTQ--KEAAW 390
Query: 650 VIVNL 664
I NL
Sbjct: 391 AISNL 395
Score = 42.7 bits (96), Expect = 0.001
Identities = 22/76 (28%), Positives = 37/76 (48%), Gaps = 1/76 (1%)
Frame = +2
Query: 383 ETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLR- 559
E W L+NI +G Q V+ A VP+ + LL +A WA+ N+ G +
Sbjct: 345 EAVWFLSNITAGNQQQVQAVIDANLVPMIIHLLDKGDFGTQKEAAWAISNLTISGRKDQV 404
Query: 560 DFVIELGVVKPLLSLI 607
++I+ V+ P +L+
Sbjct: 405 AYLIQQNVIPPFCNLL 420
Score = 30.3 bits (65), Expect = 7.6
Identities = 21/101 (20%), Positives = 38/101 (37%)
Frame = +2
Query: 305 DELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLM 484
D +I+ G++ L+ +S + W + N+ +P L+
Sbjct: 193 DYVISLGVVKPLLSFISPSIPITFLRNVTWVMVNLCRHKDPPPPMETIQEILPALCVLIH 252
Query: 485 SPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLI 607
N+ VWAL + G VI+ G+V L+ L+
Sbjct: 253 HTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLL 293
>AB002533-1|BAA19546.1| 521|Homo sapiens Qip1 protein.
Length = 521
Score = 327 bits (804), Expect = 2e-89
Identities = 159/238 (66%), Positives = 189/238 (79%), Gaps = 2/238 (0%)
Frame = +2
Query: 17 RMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYSTDEEEIDKN--LAT 190
R+ FKN G+D++ MRR+RNEV VELRKNKR+E L KRRNVP ++ +ID + +
Sbjct: 11 RLKNFKNKGRDLETMRRQRNEVVVELRKNKRDEHLLKRRNVPHEDICEDSDIDGDYRVQN 70
Query: 191 TDLDELVMNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNP 370
T L+ +V NA++ +N QL+AVQ RKLLS D+NPPID+LI +GILPILV CL R DNP
Sbjct: 71 TSLEAIVQNASS-DNQGIQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVHCLERDDNP 129
Query: 371 ALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGP 550
+LQFE AWALTNIASGTS QT VV + AVP+FL+LL SPH+NVC+QAVWALGNIIGDGP
Sbjct: 130 SLQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGP 189
Query: 551 VLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNLCRSKDPPPPLKTIQEILPGL 724
RD+VI LGVVKPLLS I IPI FLRNVTWV+VNLCR KDPPPP++TIQEILP L
Sbjct: 190 QCRDYVISLGVVKPLLSFISPSIPITFLRNVTWVMVNLCRHKDPPPPMETIQEILPAL 247
Score = 56.4 bits (130), Expect = 1e-07
Identities = 41/125 (32%), Positives = 59/125 (47%), Gaps = 1/125 (0%)
Frame = +2
Query: 293 NPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFL 472
N I +I +GI+P LV LS + +Q A+ NI +GT QT V++ A+ F
Sbjct: 274 NEQIQMVIDSGIVPHLVPLLSHQE-VKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFP 332
Query: 473 QLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLI-KSDIPIPFLRNVTW 649
LL P E + +AVW L NI VI+ +V ++ L+ K D + W
Sbjct: 333 ALLTHPKEKINKEAVWFLSNITAGNQQQVQAVIDANLVPMIIHLLDKGDFGTQ--KEAAW 390
Query: 650 VIVNL 664
I NL
Sbjct: 391 AISNL 395
Score = 42.7 bits (96), Expect = 0.001
Identities = 22/76 (28%), Positives = 37/76 (48%), Gaps = 1/76 (1%)
Frame = +2
Query: 383 ETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLR- 559
E W L+NI +G Q V+ A VP+ + LL +A WA+ N+ G +
Sbjct: 345 EAVWFLSNITAGNQQQVQAVIDANLVPMIIHLLDKGDFGTQKEAAWAISNLTISGRKDQV 404
Query: 560 DFVIELGVVKPLLSLI 607
++I+ V+ P +L+
Sbjct: 405 AYLIQQNVIPPFCNLL 420
Score = 30.3 bits (65), Expect = 7.6
Identities = 21/101 (20%), Positives = 38/101 (37%)
Frame = +2
Query: 305 DELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLM 484
D +I+ G++ L+ +S + W + N+ +P L+
Sbjct: 193 DYVISLGVVKPLLSFISPSIPITFLRNVTWVMVNLCRHKDPPPPMETIQEILPALCVLIH 252
Query: 485 SPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLI 607
N+ VWAL + G VI+ G+V L+ L+
Sbjct: 253 HTDVNILVDTVWALSYLTDAGNEQIQMVIDSGIVPHLVPLL 293
>U28386-1|AAA69957.1| 529|Homo sapiens hSRP1alpha protein.
Length = 529
Score = 246 bits (602), Expect = 7e-65
Identities = 127/245 (51%), Positives = 164/245 (66%), Gaps = 9/245 (3%)
Frame = +2
Query: 17 RMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNV---PISYSTDEEEIDKNLA 187
R+H FKN GKD EMRRRR EV VELRK K+++ + KRRNV P ++ +E N
Sbjct: 13 RLHRFKNKGKDSTEMRRRRIEVNVELRKAKKDDQMLKRRNVSSFPDDATSPLQENRNNQG 72
Query: 188 TTD--LDELVMNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRA 361
T + +D++V N+ N E QL A Q RKLLS +K PPID +I AG++P V L R
Sbjct: 73 TVNWSVDDIV-KGINSSNVENQLQATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGRT 131
Query: 362 DNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIG 541
D +QFE+AWALTNIASGTS QT VV GA+P F+ LL SPH ++ +QAVWALGNI G
Sbjct: 132 DCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAG 191
Query: 542 DGPVLRDFVIELGVVKPLLSLI----KSDIPIPFLRNVTWVIVNLCRSKDPPPPLKTIQE 709
DG V RD VI+ G V PLL+L+ S + +LRN+TW + NLCR+K+P PP+ +++
Sbjct: 192 DGSVFRDLVIKYGAVDPLLALLAVPDMSSLACGYLRNLTWTLSNLCRNKNPAPPIDAVEQ 251
Query: 710 ILPGL 724
ILP L
Sbjct: 252 ILPTL 256
Score = 62.1 bits (144), Expect = 2e-09
Identities = 42/144 (29%), Positives = 66/144 (45%)
Frame = +2
Query: 230 ENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNI 409
++PE LA L+ N I ++ G++P LV+ L ++ P + A+ NI
Sbjct: 263 DDPEV-LADTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGASELPIVT-PALRAIGNI 320
Query: 410 ASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVK 589
+GT QT V+ AGA+ VF LL +P N+ +A W + NI V+ G+V
Sbjct: 321 VTGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLV- 379
Query: 590 PLLSLIKSDIPIPFLRNVTWVIVN 661
P L + S + W + N
Sbjct: 380 PFLVSVLSKADFKTQKEAVWAVTN 403
Score = 45.2 bits (102), Expect = 3e-04
Identities = 27/87 (31%), Positives = 44/87 (50%), Gaps = 1/87 (1%)
Frame = +2
Query: 278 LSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIAS-GTSAQTNKVVHAG 454
++ + I +++ G++P LV LS+AD Q E WA+TN S GT Q +VH G
Sbjct: 362 ITAGRQDQIQQVVNHGLVPFLVSVLSKADFKT-QKEAVWAVTNYTSGGTVEQIVYLVHCG 420
Query: 455 AVPVFLQLLMSPHENVCDQAVWALGNI 535
+ + LL + + + A+ NI
Sbjct: 421 IIEPLMNLLTAKDTKIILVILDAISNI 447
Score = 31.5 bits (68), Expect = 3.3
Identities = 25/88 (28%), Positives = 41/88 (46%), Gaps = 4/88 (4%)
Frame = +2
Query: 392 WALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLR-DFV 568
W L+N+ + +P ++LL V WA+ + + DGP R V
Sbjct: 231 WTLSNLCRNKNPAPPIDAVEQILPTLVRLLHHDDPEVLADTCWAI-SYLTDGPNERIGMV 289
Query: 569 IELGVVKPLLSLI-KSDIPI--PFLRNV 643
++ GVV L+ L+ S++PI P LR +
Sbjct: 290 VKTGVVPQLVKLLGASELPIVTPALRAI 317
>U09559-1|AAA65700.1| 529|Homo sapiens Rch1 protein.
Length = 529
Score = 246 bits (602), Expect = 7e-65
Identities = 127/245 (51%), Positives = 164/245 (66%), Gaps = 9/245 (3%)
Frame = +2
Query: 17 RMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNV---PISYSTDEEEIDKNLA 187
R+H FKN GKD EMRRRR EV VELRK K+++ + KRRNV P ++ +E N
Sbjct: 13 RLHRFKNKGKDSTEMRRRRIEVNVELRKAKKDDQMLKRRNVSSFPDDATSPLQENRNNQG 72
Query: 188 TTD--LDELVMNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRA 361
T + +D++V N+ N E QL A Q RKLLS +K PPID +I AG++P V L R
Sbjct: 73 TVNWSVDDIV-KGINSSNVENQLQATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGRT 131
Query: 362 DNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIG 541
D +QFE+AWALTNIASGTS QT VV GA+P F+ LL SPH ++ +QAVWALGNI G
Sbjct: 132 DCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAG 191
Query: 542 DGPVLRDFVIELGVVKPLLSLI----KSDIPIPFLRNVTWVIVNLCRSKDPPPPLKTIQE 709
DG V RD VI+ G V PLL+L+ S + +LRN+TW + NLCR+K+P PP+ +++
Sbjct: 192 DGSVFRDLVIKYGAVDPLLALLAVPDMSSLACGYLRNLTWTLSNLCRNKNPAPPIDAVEQ 251
Query: 710 ILPGL 724
ILP L
Sbjct: 252 ILPTL 256
Score = 62.1 bits (144), Expect = 2e-09
Identities = 42/144 (29%), Positives = 66/144 (45%)
Frame = +2
Query: 230 ENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNI 409
++PE LA L+ N I ++ G++P LV+ L ++ P + A+ NI
Sbjct: 263 DDPEV-LADTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGASELPIVT-PALRAIGNI 320
Query: 410 ASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVK 589
+GT QT V+ AGA+ VF LL +P N+ +A W + NI V+ G+V
Sbjct: 321 VTGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLV- 379
Query: 590 PLLSLIKSDIPIPFLRNVTWVIVN 661
P L + S + W + N
Sbjct: 380 PFLVSVLSKADFKTQKEAVWAVTN 403
Score = 45.2 bits (102), Expect = 3e-04
Identities = 27/87 (31%), Positives = 44/87 (50%), Gaps = 1/87 (1%)
Frame = +2
Query: 278 LSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIAS-GTSAQTNKVVHAG 454
++ + I +++ G++P LV LS+AD Q E WA+TN S GT Q +VH G
Sbjct: 362 ITAGRQDQIQQVVNHGLVPFLVSVLSKADFKT-QKEAVWAVTNYTSGGTVEQIVYLVHCG 420
Query: 455 AVPVFLQLLMSPHENVCDQAVWALGNI 535
+ + LL + + + A+ NI
Sbjct: 421 IIEPLMNLLTAKDTKIILVILDAISNI 447
Score = 31.5 bits (68), Expect = 3.3
Identities = 25/88 (28%), Positives = 41/88 (46%), Gaps = 4/88 (4%)
Frame = +2
Query: 392 WALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLR-DFV 568
W L+N+ + +P ++LL V WA+ + + DGP R V
Sbjct: 231 WTLSNLCRNKNPAPPIDAVEQILPTLVRLLHHDDPEVLADTCWAI-SYLTDGPNERIGMV 289
Query: 569 IELGVVKPLLSLI-KSDIPI--PFLRNV 643
++ GVV L+ L+ S++PI P LR +
Sbjct: 290 VKTGVVPQLVKLLGASELPIVTPALRAI 317
>BC053343-1|AAH53343.1| 529|Homo sapiens karyopherin alpha 2 (RAG
cohort 1, importin alpha 1) protein.
Length = 529
Score = 246 bits (602), Expect = 7e-65
Identities = 127/245 (51%), Positives = 164/245 (66%), Gaps = 9/245 (3%)
Frame = +2
Query: 17 RMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNV---PISYSTDEEEIDKNLA 187
R+H FKN GKD EMRRRR EV VELRK K+++ + KRRNV P ++ +E N
Sbjct: 13 RLHRFKNKGKDSTEMRRRRIEVNVELRKAKKDDQMLKRRNVSSFPDDATSPLQENRNNQG 72
Query: 188 TTD--LDELVMNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRA 361
T + +D++V N+ N E QL A Q RKLLS +K PPID +I AG++P V L R
Sbjct: 73 TVNWSVDDIV-KGINSSNVENQLQATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGRT 131
Query: 362 DNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIG 541
D +QFE+AWALTNIASGTS QT VV GA+P F+ LL SPH ++ +QAVWALGNI G
Sbjct: 132 DCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAG 191
Query: 542 DGPVLRDFVIELGVVKPLLSLI----KSDIPIPFLRNVTWVIVNLCRSKDPPPPLKTIQE 709
DG V RD VI+ G V PLL+L+ S + +LRN+TW + NLCR+K+P PP+ +++
Sbjct: 192 DGSVFRDLVIKYGAVDPLLALLAVPEMSSLACGYLRNLTWTLSNLCRNKNPAPPIDAVEQ 251
Query: 710 ILPGL 724
ILP L
Sbjct: 252 ILPTL 256
Score = 62.1 bits (144), Expect = 2e-09
Identities = 42/144 (29%), Positives = 66/144 (45%)
Frame = +2
Query: 230 ENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNI 409
++PE LA L+ N I ++ G++P LV+ L ++ P + A+ NI
Sbjct: 263 DDPEV-LADTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGASELPIVT-PALRAIGNI 320
Query: 410 ASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVK 589
+GT QT V+ AGA+ VF LL +P N+ +A W + NI V+ G+V
Sbjct: 321 VTGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLV- 379
Query: 590 PLLSLIKSDIPIPFLRNVTWVIVN 661
P L + S + W + N
Sbjct: 380 PFLVSVLSKADFKTQKEAVWAVTN 403
Score = 45.2 bits (102), Expect = 3e-04
Identities = 27/87 (31%), Positives = 44/87 (50%), Gaps = 1/87 (1%)
Frame = +2
Query: 278 LSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIAS-GTSAQTNKVVHAG 454
++ + I +++ G++P LV LS+AD Q E WA+TN S GT Q +VH G
Sbjct: 362 ITAGRQDQIQQVVNHGLVPFLVSVLSKADFKT-QKEAVWAVTNYTSGGTVEQIVYLVHCG 420
Query: 455 AVPVFLQLLMSPHENVCDQAVWALGNI 535
+ + LL + + + A+ NI
Sbjct: 421 IIEPLMNLLTAKDTKIILVILDAISNI 447
Score = 31.5 bits (68), Expect = 3.3
Identities = 25/88 (28%), Positives = 41/88 (46%), Gaps = 4/88 (4%)
Frame = +2
Query: 392 WALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLR-DFV 568
W L+N+ + +P ++LL V WA+ + + DGP R V
Sbjct: 231 WTLSNLCRNKNPAPPIDAVEQILPTLVRLLHHDDPEVLADTCWAI-SYLTDGPNERIGMV 289
Query: 569 IELGVVKPLLSLI-KSDIPI--PFLRNV 643
++ GVV L+ L+ S++PI P LR +
Sbjct: 290 VKTGVVPQLVKLLGASELPIVTPALRAI 317
>AJ303086-1|CAC83080.1| 529|Homo sapiens karyopherin alpha 2
protein.
Length = 529
Score = 246 bits (602), Expect = 7e-65
Identities = 127/245 (51%), Positives = 164/245 (66%), Gaps = 9/245 (3%)
Frame = +2
Query: 17 RMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNV---PISYSTDEEEIDKNLA 187
R+H FKN GKD EMRRRR EV VELRK K+++ + KRRNV P ++ +E N
Sbjct: 13 RLHRFKNKGKDSTEMRRRRIEVNVELRKAKKDDQMLKRRNVSSFPDDATSPLQENRNNQG 72
Query: 188 TTD--LDELVMNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRA 361
T + +D++V N+ N E QL A Q RKLLS +K PPID +I AG++P V L R
Sbjct: 73 TVNWSVDDIV-KGINSSNVENQLQATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGRT 131
Query: 362 DNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIG 541
D +QFE+AWALTNIASGTS QT VV GA+P F+ LL SPH ++ +QAVWALGNI G
Sbjct: 132 DCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAG 191
Query: 542 DGPVLRDFVIELGVVKPLLSLI----KSDIPIPFLRNVTWVIVNLCRSKDPPPPLKTIQE 709
DG V RD VI+ G V PLL+L+ S + +LRN+TW + NLCR+K+P PP+ +++
Sbjct: 192 DGSVFRDLVIKYGAVDPLLALLAVPDMSSLACGYLRNLTWTLSNLCRNKNPAPPIDAVEQ 251
Query: 710 ILPGL 724
ILP L
Sbjct: 252 ILPTL 256
Score = 62.1 bits (144), Expect = 2e-09
Identities = 42/144 (29%), Positives = 66/144 (45%)
Frame = +2
Query: 230 ENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNI 409
++PE LA L+ N I ++ G++P LV+ L ++ P + A+ NI
Sbjct: 263 DDPEV-LADTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGASELPIVT-PALRAIGNI 320
Query: 410 ASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVK 589
+GT QT V+ AGA+ VF LL +P N+ +A W + NI V+ G+V
Sbjct: 321 VTGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLV- 379
Query: 590 PLLSLIKSDIPIPFLRNVTWVIVN 661
P L + S + W + N
Sbjct: 380 PFLVSVLSKADFKTQKEAVWAVTN 403
Score = 45.2 bits (102), Expect = 3e-04
Identities = 27/87 (31%), Positives = 44/87 (50%), Gaps = 1/87 (1%)
Frame = +2
Query: 278 LSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIAS-GTSAQTNKVVHAG 454
++ + I +++ G++P LV LS+AD Q E WA+TN S GT Q +VH G
Sbjct: 362 ITAGRQDQIQQVVNHGLVPFLVSVLSKADFKT-QKEAVWAVTNYTSGGTVEQIVYLVHCG 420
Query: 455 AVPVFLQLLMSPHENVCDQAVWALGNI 535
+ + LL + + + A+ NI
Sbjct: 421 IIEPLMNLLTAKDTKIILVILDAISNI 447
Score = 31.5 bits (68), Expect = 3.3
Identities = 25/88 (28%), Positives = 41/88 (46%), Gaps = 4/88 (4%)
Frame = +2
Query: 392 WALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLR-DFV 568
W L+N+ + +P ++LL V WA+ + + DGP R V
Sbjct: 231 WTLSNLCRNKNPAPPIDAVEQILPTLVRLLHHDDPEVLADTCWAI-SYLTDGPNERIGMV 289
Query: 569 IELGVVKPLLSLI-KSDIPI--PFLRNV 643
++ GVV L+ L+ S++PI P LR +
Sbjct: 290 VKTGVVPQLVKLLGASELPIVTPALRAI 317
>BT006665-1|AAP35311.1| 529|Homo sapiens karyopherin alpha 2 (RAG
cohort 1, importin alpha 1) protein.
Length = 529
Score = 246 bits (601), Expect = 9e-65
Identities = 127/245 (51%), Positives = 164/245 (66%), Gaps = 9/245 (3%)
Frame = +2
Query: 17 RMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNV---PISYSTDEEEIDKNLA 187
R+H FKN GKD EMRRRR EV VELRK K+++ + KRRNV P ++ +E N
Sbjct: 13 RLHRFKNKGKDSTEMRRRRIEVNVELRKAKKDDQMLKRRNVSSFPDDATSPLQENRNNQG 72
Query: 188 TTD--LDELVMNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRA 361
T + +D++V N+ N E QL A Q RKLLS +K PPID +I AG++P V L R
Sbjct: 73 TVNWSVDDIV-KGINSSNVENQLQATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGRT 131
Query: 362 DNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIG 541
D +QFE+AWALTNIASGTS QT VV GA+P F+ LL SPH ++ +QAVWALGNI G
Sbjct: 132 DCSPIQFESAWALTNIASGTSEQTKVVVDGGAIPAFISLLASPHAHISEQAVWALGNIAG 191
Query: 542 DGPVLRDFVIELGVVKPLLSLI----KSDIPIPFLRNVTWVIVNLCRSKDPPPPLKTIQE 709
DG V RD VI+ G V PLL+L+ S + +LRN+TW + NLCR+K+P PP+ +++
Sbjct: 192 DGSVFRDLVIKYGAVDPLLALLAVPDMSSLACGYLRNLTWTLSNLCRNKNPAPPIDAVEQ 251
Query: 710 ILPGL 724
ILP L
Sbjct: 252 ILPTL 256
Score = 62.1 bits (144), Expect = 2e-09
Identities = 42/144 (29%), Positives = 66/144 (45%)
Frame = +2
Query: 230 ENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNI 409
++PE LA L+ N I ++ G++P LV+ L ++ P + A+ NI
Sbjct: 263 DDPEV-LADTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGASELPIVT-PALRAIGNI 320
Query: 410 ASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVK 589
+GT QT V+ AGA+ VF LL +P N+ +A W + NI V+ G+V
Sbjct: 321 VTGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLV- 379
Query: 590 PLLSLIKSDIPIPFLRNVTWVIVN 661
P L + S + W + N
Sbjct: 380 PFLVSVLSKADFKTQKEAVWAVTN 403
Score = 45.2 bits (102), Expect = 3e-04
Identities = 27/87 (31%), Positives = 44/87 (50%), Gaps = 1/87 (1%)
Frame = +2
Query: 278 LSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIAS-GTSAQTNKVVHAG 454
++ + I +++ G++P LV LS+AD Q E WA+TN S GT Q +VH G
Sbjct: 362 ITAGRQDQIQQVVNHGLVPFLVSVLSKADFKT-QKEAVWAVTNYTSGGTVEQIVYLVHCG 420
Query: 455 AVPVFLQLLMSPHENVCDQAVWALGNI 535
+ + LL + + + A+ NI
Sbjct: 421 IIEPLMNLLTAKDTKIILVILDAISNI 447
Score = 31.5 bits (68), Expect = 3.3
Identities = 25/88 (28%), Positives = 41/88 (46%), Gaps = 4/88 (4%)
Frame = +2
Query: 392 WALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLR-DFV 568
W L+N+ + +P ++LL V WA+ + + DGP R V
Sbjct: 231 WTLSNLCRNKNPAPPIDAVEQILPTLVRLLHHDDPEVLADTCWAI-SYLTDGPNERIGMV 289
Query: 569 IELGVVKPLLSLI-KSDIPI--PFLRNV 643
++ GVV L+ L+ S++PI P LR +
Sbjct: 290 VKTGVVPQLVKLLGASELPIVTPALRAI 317
>BC005978-1|AAH05978.1| 529|Homo sapiens karyopherin alpha 2 (RAG
cohort 1, importin alpha 1) protein.
Length = 529
Score = 246 bits (601), Expect = 9e-65
Identities = 127/245 (51%), Positives = 164/245 (66%), Gaps = 9/245 (3%)
Frame = +2
Query: 17 RMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNV---PISYSTDEEEIDKNLA 187
R+H FKN GKD EMRRRR EV VELRK K+++ + KRRNV P ++ +E N
Sbjct: 13 RLHRFKNKGKDSTEMRRRRIEVNVELRKAKKDDQMLKRRNVSSFPDDATSPLQENRNNQG 72
Query: 188 TTD--LDELVMNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRA 361
T + +D++V N+ N E QL A Q RKLLS +K PPID +I AG++P V L R
Sbjct: 73 TVNWSVDDIV-KGINSSNVENQLQATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGRT 131
Query: 362 DNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIG 541
D +QFE+AWALTNIASGTS QT VV GA+P F+ LL SPH ++ +QAVWALGNI G
Sbjct: 132 DCSPIQFESAWALTNIASGTSEQTKVVVDGGAIPAFISLLASPHAHISEQAVWALGNIAG 191
Query: 542 DGPVLRDFVIELGVVKPLLSLI----KSDIPIPFLRNVTWVIVNLCRSKDPPPPLKTIQE 709
DG V RD VI+ G V PLL+L+ S + +LRN+TW + NLCR+K+P PP+ +++
Sbjct: 192 DGSVFRDLVIKYGAVDPLLALLAVPDMSSLACGYLRNLTWTLSNLCRNKNPAPPIDAVEQ 251
Query: 710 ILPGL 724
ILP L
Sbjct: 252 ILPTL 256
Score = 62.1 bits (144), Expect = 2e-09
Identities = 42/144 (29%), Positives = 66/144 (45%)
Frame = +2
Query: 230 ENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNI 409
++PE LA L+ N I ++ G++P LV+ L ++ P + A+ NI
Sbjct: 263 DDPEV-LADTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGASELPIVT-PALRAIGNI 320
Query: 410 ASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVK 589
+GT QT V+ AGA+ VF LL +P N+ +A W + NI V+ G+V
Sbjct: 321 VTGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLV- 379
Query: 590 PLLSLIKSDIPIPFLRNVTWVIVN 661
P L + S + W + N
Sbjct: 380 PFLVSVLSKADFKTQKEAVWAVTN 403
Score = 45.2 bits (102), Expect = 3e-04
Identities = 27/87 (31%), Positives = 44/87 (50%), Gaps = 1/87 (1%)
Frame = +2
Query: 278 LSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIAS-GTSAQTNKVVHAG 454
++ + I +++ G++P LV LS+AD Q E WA+TN S GT Q +VH G
Sbjct: 362 ITAGRQDQIQQVVNHGLVPFLVSVLSKADFKT-QKEAVWAVTNYTSGGTVEQIVYLVHCG 420
Query: 455 AVPVFLQLLMSPHENVCDQAVWALGNI 535
+ + LL + + + A+ NI
Sbjct: 421 IIEPLMNLLTAKDTKIILVILDAISNI 447
Score = 31.5 bits (68), Expect = 3.3
Identities = 25/88 (28%), Positives = 41/88 (46%), Gaps = 4/88 (4%)
Frame = +2
Query: 392 WALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLR-DFV 568
W L+N+ + +P ++LL V WA+ + + DGP R V
Sbjct: 231 WTLSNLCRNKNPAPPIDAVEQILPTLVRLLHHDDPEVLADTCWAI-SYLTDGPNERIGMV 289
Query: 569 IELGVVKPLLSLI-KSDIPI--PFLRNV 643
++ GVV L+ L+ S++PI P LR +
Sbjct: 290 VKTGVVPQLVKLLGASELPIVTPALRAI 317
>BC067848-1|AAH67848.1| 529|Homo sapiens karyopherin alpha 2 (RAG
cohort 1, importin alpha 1) protein.
Length = 529
Score = 240 bits (587), Expect = 4e-63
Identities = 125/245 (51%), Positives = 162/245 (66%), Gaps = 9/245 (3%)
Frame = +2
Query: 17 RMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNV---PISYSTDEEEIDKNLA 187
R+H FKN GKD EMRRRR EV VELRK K+++ + KRRNV P ++ +E N
Sbjct: 13 RLHRFKNKGKDSTEMRRRRIEVNVELRKAKKDDQMLKRRNVSSFPDDATSPLQENRNNQG 72
Query: 188 TTD--LDELVMNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRA 361
T + +D++V N+ N E QL A Q RKLLS +K PPID +I AG++P V L R
Sbjct: 73 TVNWSVDDIV-KGINSSNVENQLQATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGRT 131
Query: 362 DNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIG 541
D +QFE+AWALTNIASGTS QT VV GA+ F+ LL SPH ++ +Q VWALGNI G
Sbjct: 132 DCSPIQFESAWALTNIASGTSEQTKAVVDGGAIRAFISLLASPHAHISEQDVWALGNIAG 191
Query: 542 DGPVLRDFVIELGVVKPLLSLI----KSDIPIPFLRNVTWVIVNLCRSKDPPPPLKTIQE 709
DG V RD VI+ G V PLL+L+ S + +LRN+TW + NLCR+K+P PP+ +++
Sbjct: 192 DGSVFRDLVIKYGAVDPLLALLAVPDMSSLACGYLRNLTWTLSNLCRNKNPAPPIDAVEQ 251
Query: 710 ILPGL 724
ILP L
Sbjct: 252 ILPTL 256
Score = 62.1 bits (144), Expect = 2e-09
Identities = 42/144 (29%), Positives = 66/144 (45%)
Frame = +2
Query: 230 ENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNI 409
++PE LA L+ N I ++ G++P LV+ L ++ P + A+ NI
Sbjct: 263 DDPEV-LADTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGASELPIVT-PALRAIGNI 320
Query: 410 ASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVK 589
+GT QT V+ AGA+ VF LL +P N+ +A W + NI V+ G+V
Sbjct: 321 VTGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLV- 379
Query: 590 PLLSLIKSDIPIPFLRNVTWVIVN 661
P L + S + W + N
Sbjct: 380 PFLVSVLSKADFKTQKEAVWAVTN 403
Score = 45.2 bits (102), Expect = 3e-04
Identities = 27/87 (31%), Positives = 44/87 (50%), Gaps = 1/87 (1%)
Frame = +2
Query: 278 LSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIAS-GTSAQTNKVVHAG 454
++ + I +++ G++P LV LS+AD Q E WA+TN S GT Q +VH G
Sbjct: 362 ITAGRQDQIQQVVNHGLVPFLVSVLSKADFKT-QKEAVWAVTNYTSGGTVEQIVYLVHCG 420
Query: 455 AVPVFLQLLMSPHENVCDQAVWALGNI 535
+ + LL + + + A+ NI
Sbjct: 421 IIEPLMNLLTAKDTKIILVILDAISNI 447
Score = 31.5 bits (68), Expect = 3.3
Identities = 25/88 (28%), Positives = 41/88 (46%), Gaps = 4/88 (4%)
Frame = +2
Query: 392 WALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLR-DFV 568
W L+N+ + +P ++LL V WA+ + + DGP R V
Sbjct: 231 WTLSNLCRNKNPAPPIDAVEQILPTLVRLLHHDDPEVLADTCWAI-SYLTDGPNERIGMV 289
Query: 569 IELGVVKPLLSLI-KSDIPI--PFLRNV 643
++ GVV L+ L+ S++PI P LR +
Sbjct: 290 VKTGVVPQLVKLLGASELPIVTPALRAI 317
>CR456743-1|CAG33024.1| 538|Homo sapiens KPNA1 protein.
Length = 538
Score = 207 bits (505), Expect = 4e-53
Identities = 110/247 (44%), Positives = 148/247 (59%), Gaps = 14/247 (5%)
Frame = +2
Query: 17 RMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYSTDEEEI--DKNLAT 190
R+ +KN + DEMRRRR E ++LRK KREE L KRRNV + EEE+ D
Sbjct: 10 RLKSYKNKSLNPDEMRRRREEEGLQLRKQKREEQLFKRRNVATAEEETEEEVMSDGGFHE 69
Query: 191 TDLDELVMNAAN-----------AENPEAQLAAVQQCRKLLSCDKNPPIDELIAA-GILP 334
++ + M +++PE QL+A Q+ RKLLS + NPPIDE+I+ G++
Sbjct: 70 AQINNMEMAPGGVITSDMIEMIFSKSPEQQLSATQKFRKLLSKEPNPPIDEVISTPGVVA 129
Query: 335 ILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQA 514
V+ L R +N LQFE+AW LTNIASG S QT V+ AGAVP+F++LL S E+V +QA
Sbjct: 130 RFVEFLKRKENCTLQFESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFEDVQEQA 189
Query: 515 VWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNLCRSKDPPPPL 694
VWALGNI GD + RD+V++ ++ PLL L + RN W + NLCR K PPP
Sbjct: 190 VWALGNIAGDSTMCRDYVLDCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKSPPPEF 249
Query: 695 KTIQEIL 715
+ L
Sbjct: 250 AKVSPCL 256
Score = 52.8 bits (121), Expect = 1e-06
Identities = 27/100 (27%), Positives = 49/100 (49%), Gaps = 1/100 (1%)
Frame = +2
Query: 311 LIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSP 490
++ L L+ LS + +++ E W ++NI +G AQ V+ A P + +L +
Sbjct: 334 ILNCSALQSLLHLLS-SPKESIKKEACWTISNITAGNRAQIQTVIDANIFPALISILQTA 392
Query: 491 HENVCDQAVWALGNIIGDGPVLR-DFVIELGVVKPLLSLI 607
+A WA+ N G + +++ELG +KPL L+
Sbjct: 393 EFRTRKEAAWAITNATSGGSAEQIKYLVELGCIKPLCDLL 432
Score = 46.0 bits (104), Expect = 1e-04
Identities = 31/125 (24%), Positives = 56/125 (44%)
Frame = +2
Query: 290 KNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVF 469
K+PP + + L +L L +D L + WAL+ ++ G + + V+ AG
Sbjct: 243 KSPPPEFAKVSPCLNVLSWLLFVSDTDVLA-DACWALSYLSDGPNDKIQAVIDAGVCRRL 301
Query: 470 LQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTW 649
++LLM V A+ A+GNI+ + ++ ++ LL L+ S + W
Sbjct: 302 VELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALQSLLHLLSSP-KESIKKEACW 360
Query: 650 VIVNL 664
I N+
Sbjct: 361 TISNI 365
Score = 43.6 bits (98), Expect = 8e-04
Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 1/102 (0%)
Frame = +2
Query: 305 DELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLM 484
D ++ ILP L+Q S+ + + WAL+N+ G S + + V LL
Sbjct: 205 DYVLDCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKSPPPEFAKVSPCLNVLSWLLF 264
Query: 485 SPHENVCDQAVWALGNIIGDGPVLR-DFVIELGVVKPLLSLI 607
+V A WAL + + DGP + VI+ GV + L+ L+
Sbjct: 265 VSDTDVLADACWAL-SYLSDGPNDKIQAVIDAGVCRRLVELL 305
Score = 39.5 bits (88), Expect = 0.012
Identities = 27/80 (33%), Positives = 38/80 (47%), Gaps = 1/80 (1%)
Frame = +2
Query: 302 IDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNK-VVHAGAVPVFLQL 478
I +I A I P L+ L A+ + E AWA+TN SG SA+ K +V G + L
Sbjct: 373 IQTVIDANIFPALISILQTAEFRTRK-EAAWAITNATSGGSAEQIKYLVELGCIKPLCDL 431
Query: 479 LMSPHENVCDQAVWALGNII 538
L + A+ L NI+
Sbjct: 432 LTVMDSKIVQVALNGLENIL 451
>BT006959-1|AAP35605.1| 538|Homo sapiens karyopherin alpha 1
(importin alpha 5) protein.
Length = 538
Score = 207 bits (505), Expect = 4e-53
Identities = 110/247 (44%), Positives = 148/247 (59%), Gaps = 14/247 (5%)
Frame = +2
Query: 17 RMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYSTDEEEI--DKNLAT 190
R+ +KN + DEMRRRR E ++LRK KREE L KRRNV + EEE+ D
Sbjct: 10 RLKSYKNKSLNPDEMRRRREEEGLQLRKQKREEQLFKRRNVATAEEETEEEVMSDGGFHE 69
Query: 191 TDLDELVMNAAN-----------AENPEAQLAAVQQCRKLLSCDKNPPIDELIAA-GILP 334
++ + M +++PE QL+A Q+ RKLLS + NPPIDE+I+ G++
Sbjct: 70 AQINNMEMAPGGVITSDMIEMIFSKSPEQQLSATQKFRKLLSKEPNPPIDEVISTPGVVA 129
Query: 335 ILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQA 514
V+ L R +N LQFE+AW LTNIASG S QT V+ AGAVP+F++LL S E+V +QA
Sbjct: 130 RFVEFLKRKENCTLQFESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFEDVQEQA 189
Query: 515 VWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNLCRSKDPPPPL 694
VWALGNI GD + RD+V++ ++ PLL L + RN W + NLCR K PPP
Sbjct: 190 VWALGNIAGDSTMCRDYVLDCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKSPPPEF 249
Query: 695 KTIQEIL 715
+ L
Sbjct: 250 AKVSPCL 256
Score = 52.8 bits (121), Expect = 1e-06
Identities = 27/100 (27%), Positives = 49/100 (49%), Gaps = 1/100 (1%)
Frame = +2
Query: 311 LIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSP 490
++ L L+ LS + +++ E W ++NI +G AQ V+ A P + +L +
Sbjct: 334 ILNCSALQSLLHLLS-SPKESIKKEACWTISNITAGNRAQIQTVIDANIFPALISILQTA 392
Query: 491 HENVCDQAVWALGNIIGDGPVLR-DFVIELGVVKPLLSLI 607
+A WA+ N G + +++ELG +KPL L+
Sbjct: 393 EFRTRKEAAWAITNATSGGSAEQIKYLVELGCIKPLCDLL 432
Score = 46.0 bits (104), Expect = 1e-04
Identities = 31/125 (24%), Positives = 56/125 (44%)
Frame = +2
Query: 290 KNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVF 469
K+PP + + L +L L +D L + WAL+ ++ G + + V+ AG
Sbjct: 243 KSPPPEFAKVSPCLNVLSWLLFVSDTDVLA-DACWALSYLSDGPNDKIQAVIDAGVCRRL 301
Query: 470 LQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTW 649
++LLM V A+ A+GNI+ + ++ ++ LL L+ S + W
Sbjct: 302 VELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALQSLLHLLSSP-KESIKKEACW 360
Query: 650 VIVNL 664
I N+
Sbjct: 361 TISNI 365
Score = 43.6 bits (98), Expect = 8e-04
Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 1/102 (0%)
Frame = +2
Query: 305 DELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLM 484
D ++ ILP L+Q S+ + + WAL+N+ G S + + V LL
Sbjct: 205 DYVLDCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKSPPPEFAKVSPCLNVLSWLLF 264
Query: 485 SPHENVCDQAVWALGNIIGDGPVLR-DFVIELGVVKPLLSLI 607
+V A WAL + + DGP + VI+ GV + L+ L+
Sbjct: 265 VSDTDVLADACWAL-SYLSDGPNDKIQAVIDAGVCRRLVELL 305
Score = 39.5 bits (88), Expect = 0.012
Identities = 27/80 (33%), Positives = 38/80 (47%), Gaps = 1/80 (1%)
Frame = +2
Query: 302 IDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNK-VVHAGAVPVFLQL 478
I +I A I P L+ L A+ + E AWA+TN SG SA+ K +V G + L
Sbjct: 373 IQTVIDANIFPALISILQTAEFRTRK-EAAWAITNATSGGSAEQIKYLVELGCIKPLCDL 431
Query: 479 LMSPHENVCDQAVWALGNII 538
L + A+ L NI+
Sbjct: 432 LTVMDSKIVQVALNGLENIL 451
>BC090864-1|AAH90864.1| 538|Homo sapiens karyopherin alpha 1
(importin alpha 5) protein.
Length = 538
Score = 207 bits (505), Expect = 4e-53
Identities = 110/247 (44%), Positives = 148/247 (59%), Gaps = 14/247 (5%)
Frame = +2
Query: 17 RMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYSTDEEEI--DKNLAT 190
R+ +KN + DEMRRRR E ++LRK KREE L KRRNV + EEE+ D
Sbjct: 10 RLKSYKNKSLNPDEMRRRREEEGLQLRKQKREEQLFKRRNVATAEEETEEEVMSDGGFHE 69
Query: 191 TDLDELVMNAAN-----------AENPEAQLAAVQQCRKLLSCDKNPPIDELIAA-GILP 334
++ + M +++PE QL+A Q+ RKLLS + NPPIDE+I+ G++
Sbjct: 70 AQINNMEMAPGGVITSDMIEMIFSKSPEQQLSATQKFRKLLSKEPNPPIDEVISTPGVVA 129
Query: 335 ILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQA 514
V+ L R +N LQFE+AW LTNIASG S QT V+ AGAVP+F++LL S E+V +QA
Sbjct: 130 RFVEFLKRKENCTLQFESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFEDVQEQA 189
Query: 515 VWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNLCRSKDPPPPL 694
VWALGNI GD + RD+V++ ++ PLL L + RN W + NLCR K PPP
Sbjct: 190 VWALGNIAGDSTMYRDYVLDCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKSPPPEF 249
Query: 695 KTIQEIL 715
+ L
Sbjct: 250 AKVSPCL 256
Score = 52.8 bits (121), Expect = 1e-06
Identities = 27/100 (27%), Positives = 49/100 (49%), Gaps = 1/100 (1%)
Frame = +2
Query: 311 LIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSP 490
++ L L+ LS + +++ E W ++NI +G AQ V+ A P + +L +
Sbjct: 334 ILNCSALQSLLHLLS-SPKESIKKEACWTISNITAGNRAQIQTVIDANIFPALISILQTA 392
Query: 491 HENVCDQAVWALGNIIGDGPVLR-DFVIELGVVKPLLSLI 607
+A WA+ N G + +++ELG +KPL L+
Sbjct: 393 EFRTRKEAAWAITNATSGGSAEQIKYLVELGCIKPLCDLL 432
Score = 46.0 bits (104), Expect = 1e-04
Identities = 31/125 (24%), Positives = 56/125 (44%)
Frame = +2
Query: 290 KNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVF 469
K+PP + + L +L L +D L + WAL+ ++ G + + V+ AG
Sbjct: 243 KSPPPEFAKVSPCLNVLSWLLFVSDTDVLA-DACWALSYLSDGPNDKIQAVIDAGVCRRL 301
Query: 470 LQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTW 649
++LLM V A+ A+GNI+ + ++ ++ LL L+ S + W
Sbjct: 302 VELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALQSLLHLLSSP-KESIKKEACW 360
Query: 650 VIVNL 664
I N+
Sbjct: 361 TISNI 365
Score = 43.6 bits (98), Expect = 8e-04
Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 1/102 (0%)
Frame = +2
Query: 305 DELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLM 484
D ++ ILP L+Q S+ + + WAL+N+ G S + + V LL
Sbjct: 205 DYVLDCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKSPPPEFAKVSPCLNVLSWLLF 264
Query: 485 SPHENVCDQAVWALGNIIGDGPVLR-DFVIELGVVKPLLSLI 607
+V A WAL + + DGP + VI+ GV + L+ L+
Sbjct: 265 VSDTDVLADACWAL-SYLSDGPNDKIQAVIDAGVCRRLVELL 305
Score = 39.5 bits (88), Expect = 0.012
Identities = 27/80 (33%), Positives = 38/80 (47%), Gaps = 1/80 (1%)
Frame = +2
Query: 302 IDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNK-VVHAGAVPVFLQL 478
I +I A I P L+ L A+ + E AWA+TN SG SA+ K +V G + L
Sbjct: 373 IQTVIDANIFPALISILQTAEFRTRK-EAAWAITNATSGGSAEQIKYLVELGCIKPLCDL 431
Query: 479 LMSPHENVCDQAVWALGNII 538
L + A+ L NI+
Sbjct: 432 LTVMDSKIVQVALNGLENIL 451
>BC003009-1|AAH03009.1| 538|Homo sapiens karyopherin alpha 1
(importin alpha 5) protein.
Length = 538
Score = 207 bits (505), Expect = 4e-53
Identities = 110/247 (44%), Positives = 148/247 (59%), Gaps = 14/247 (5%)
Frame = +2
Query: 17 RMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYSTDEEEI--DKNLAT 190
R+ +KN + DEMRRRR E ++LRK KREE L KRRNV + EEE+ D
Sbjct: 10 RLKSYKNKSLNPDEMRRRREEEGLQLRKQKREEQLFKRRNVATAEEETEEEVMSDGGFHE 69
Query: 191 TDLDELVMNAAN-----------AENPEAQLAAVQQCRKLLSCDKNPPIDELIAA-GILP 334
++ + M +++PE QL+A Q+ RKLLS + NPPIDE+I+ G++
Sbjct: 70 AQINNMEMAPGGVITSDMIEMIFSKSPEQQLSATQKFRKLLSKEPNPPIDEVISTPGVVA 129
Query: 335 ILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQA 514
V+ L R +N LQFE+AW LTNIASG S QT V+ AGAVP+F++LL S E+V +QA
Sbjct: 130 RFVEFLKRKENCTLQFESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFEDVQEQA 189
Query: 515 VWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNLCRSKDPPPPL 694
VWALGNI GD + RD+V++ ++ PLL L + RN W + NLCR K PPP
Sbjct: 190 VWALGNIAGDSTMCRDYVLDCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKSPPPEF 249
Query: 695 KTIQEIL 715
+ L
Sbjct: 250 AKVSPCL 256
Score = 52.8 bits (121), Expect = 1e-06
Identities = 27/100 (27%), Positives = 49/100 (49%), Gaps = 1/100 (1%)
Frame = +2
Query: 311 LIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSP 490
++ L L+ LS + +++ E W ++NI +G AQ V+ A P + +L +
Sbjct: 334 ILNCSALQSLLHLLS-SPKESIKKEACWTISNITAGNRAQIQTVIDANIFPALISILQTA 392
Query: 491 HENVCDQAVWALGNIIGDGPVLR-DFVIELGVVKPLLSLI 607
+A WA+ N G + +++ELG +KPL L+
Sbjct: 393 EFRTRKEAAWAITNATSGGSAEQIKYLVELGCIKPLCDLL 432
Score = 46.0 bits (104), Expect = 1e-04
Identities = 31/125 (24%), Positives = 56/125 (44%)
Frame = +2
Query: 290 KNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVF 469
K+PP + + L +L L +D L + WAL+ ++ G + + V+ AG
Sbjct: 243 KSPPPEFAKVSPCLNVLSWLLFVSDTDVLA-DACWALSYLSDGPNDKIQAVIDAGVCRRL 301
Query: 470 LQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTW 649
++LLM V A+ A+GNI+ + ++ ++ LL L+ S + W
Sbjct: 302 VELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALQSLLHLLSSP-KESIKKEACW 360
Query: 650 VIVNL 664
I N+
Sbjct: 361 TISNI 365
Score = 43.6 bits (98), Expect = 8e-04
Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 1/102 (0%)
Frame = +2
Query: 305 DELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLM 484
D ++ ILP L+Q S+ + + WAL+N+ G S + + V LL
Sbjct: 205 DYVLDCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKSPPPEFAKVSPCLNVLSWLLF 264
Query: 485 SPHENVCDQAVWALGNIIGDGPVLR-DFVIELGVVKPLLSLI 607
+V A WAL + + DGP + VI+ GV + L+ L+
Sbjct: 265 VSDTDVLADACWAL-SYLSDGPNDKIQAVIDAGVCRRLVELL 305
Score = 39.5 bits (88), Expect = 0.012
Identities = 27/80 (33%), Positives = 38/80 (47%), Gaps = 1/80 (1%)
Frame = +2
Query: 302 IDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNK-VVHAGAVPVFLQL 478
I +I A I P L+ L A+ + E AWA+TN SG SA+ K +V G + L
Sbjct: 373 IQTVIDANIFPALISILQTAEFRTRK-EAAWAITNATSGGSAEQIKYLVELGCIKPLCDL 431
Query: 479 LMSPHENVCDQAVWALGNII 538
L + A+ L NI+
Sbjct: 432 LTVMDSKIVQVALNGLENIL 451
>BC002374-1|AAH02374.1| 538|Homo sapiens karyopherin alpha 1
(importin alpha 5) protein.
Length = 538
Score = 207 bits (505), Expect = 4e-53
Identities = 110/247 (44%), Positives = 148/247 (59%), Gaps = 14/247 (5%)
Frame = +2
Query: 17 RMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYSTDEEEI--DKNLAT 190
R+ +KN + DEMRRRR E ++LRK KREE L KRRNV + EEE+ D
Sbjct: 10 RLKSYKNKSLNPDEMRRRREEEGLQLRKQKREEQLFKRRNVATAEEETEEEVMSDGGFHE 69
Query: 191 TDLDELVMNAAN-----------AENPEAQLAAVQQCRKLLSCDKNPPIDELIAA-GILP 334
++ + M +++PE QL+A Q+ RKLLS + NPPIDE+I+ G++
Sbjct: 70 AQINNMEMAPGGVITSDMIEMIFSKSPEQQLSATQKFRKLLSKEPNPPIDEVISTPGVVA 129
Query: 335 ILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQA 514
V+ L R +N LQFE+AW LTNIASG S QT V+ AGAVP+F++LL S E+V +QA
Sbjct: 130 RFVEFLKRKENCTLQFESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFEDVQEQA 189
Query: 515 VWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNLCRSKDPPPPL 694
VWALGNI GD + RD+V++ ++ PLL L + RN W + NLCR K PPP
Sbjct: 190 VWALGNIAGDSTMCRDYVLDCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKSPPPEF 249
Query: 695 KTIQEIL 715
+ L
Sbjct: 250 AKVSPCL 256
Score = 52.8 bits (121), Expect = 1e-06
Identities = 27/100 (27%), Positives = 49/100 (49%), Gaps = 1/100 (1%)
Frame = +2
Query: 311 LIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSP 490
++ L L+ LS + +++ E W ++NI +G AQ V+ A P + +L +
Sbjct: 334 ILNCSALQSLLHLLS-SPKESIKKEACWTISNITAGNRAQIQTVIDANIFPALISILQTA 392
Query: 491 HENVCDQAVWALGNIIGDGPVLR-DFVIELGVVKPLLSLI 607
+A WA+ N G + +++ELG +KPL L+
Sbjct: 393 EFRTRKEAAWAITNATSGGSAEQIKYLVELGCIKPLCDLL 432
Score = 46.0 bits (104), Expect = 1e-04
Identities = 31/125 (24%), Positives = 56/125 (44%)
Frame = +2
Query: 290 KNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVF 469
K+PP + + L +L L +D L + WAL+ ++ G + + V+ AG
Sbjct: 243 KSPPPEFAKVSPCLNVLSWLLFVSDTDVLA-DACWALSYLSDGPNDKIQAVIDAGVCRRL 301
Query: 470 LQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTW 649
++LLM V A+ A+GNI+ + ++ ++ LL L+ S + W
Sbjct: 302 VELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALQSLLHLLSSP-KESIKKEACW 360
Query: 650 VIVNL 664
I N+
Sbjct: 361 TISNI 365
Score = 43.6 bits (98), Expect = 8e-04
Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 1/102 (0%)
Frame = +2
Query: 305 DELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLM 484
D ++ ILP L+Q S+ + + WAL+N+ G S + + V LL
Sbjct: 205 DYVLDCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKSPPPEFAKVSPCLNVLSWLLF 264
Query: 485 SPHENVCDQAVWALGNIIGDGPVLR-DFVIELGVVKPLLSLI 607
+V A WAL + + DGP + VI+ GV + L+ L+
Sbjct: 265 VSDTDVLADACWAL-SYLSDGPNDKIQAVIDAGVCRRLVELL 305
Score = 39.5 bits (88), Expect = 0.012
Identities = 27/80 (33%), Positives = 38/80 (47%), Gaps = 1/80 (1%)
Frame = +2
Query: 302 IDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNK-VVHAGAVPVFLQL 478
I +I A I P L+ L A+ + E AWA+TN SG SA+ K +V G + L
Sbjct: 373 IQTVIDANIFPALISILQTAEFRTRK-EAAWAITNATSGGSAEQIKYLVELGCIKPLCDL 431
Query: 479 LMSPHENVCDQAVWALGNII 538
L + A+ L NI+
Sbjct: 432 LTVMDSKIVQVALNGLENIL 451
>S75295-1|AAC60648.1| 538|Homo sapiens nucleoprotein interactor 1
protein.
Length = 538
Score = 204 bits (497), Expect = 3e-52
Identities = 109/247 (44%), Positives = 147/247 (59%), Gaps = 14/247 (5%)
Frame = +2
Query: 17 RMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYSTDEEEI--DKNLAT 190
R+ +KN + DEMRRRR E ++LRK KREE L KRRNV + EEE+ D
Sbjct: 10 RLKSYKNKSLNPDEMRRRREEEGLQLRKQKREEQLFKRRNVATAEEETEEEVMSDGGFHE 69
Query: 191 TDLDELVMNAAN-----------AENPEAQLAAVQQCRKLLSCDKNPPIDELIAA-GILP 334
+ + M +++PE QL+A Q+ RKLLS + NPPIDE+I+ G++
Sbjct: 70 AQISNMEMAPGGVITSDMIEMIFSKSPEQQLSATQKFRKLLSKEPNPPIDEVISTPGVVA 129
Query: 335 ILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQA 514
V+ L R +N +LQFE+AW LTNIASG S QT V+ A AVP+F++LL S E+V +QA
Sbjct: 130 RFVEFLKRKENCSLQFESAWVLTNIASGNSLQTRIVIQARAVPIFIELLSSEFEDVQEQA 189
Query: 515 VWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNLCRSKDPPPPL 694
VWALGNI GD + RD+V++ ++ PLL L + RN W + NLCR K PPP
Sbjct: 190 VWALGNIAGDSTMCRDYVLDCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKSPPPEF 249
Query: 695 KTIQEIL 715
+ L
Sbjct: 250 AKVSPCL 256
Score = 52.8 bits (121), Expect = 1e-06
Identities = 27/100 (27%), Positives = 49/100 (49%), Gaps = 1/100 (1%)
Frame = +2
Query: 311 LIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSP 490
++ L L+ LS + +++ E W ++NI +G AQ V+ A P + +L +
Sbjct: 334 ILNCSALQSLLHLLS-SPKESIKKEACWTISNITAGNRAQIQTVIDANIFPALISILQTA 392
Query: 491 HENVCDQAVWALGNIIGDGPVLR-DFVIELGVVKPLLSLI 607
+A WA+ N G + +++ELG +KPL L+
Sbjct: 393 EFRTRKEAAWAITNATSGGSAEQIKYLVELGCIKPLCDLL 432
Score = 46.0 bits (104), Expect = 1e-04
Identities = 31/125 (24%), Positives = 56/125 (44%)
Frame = +2
Query: 290 KNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVF 469
K+PP + + L +L L +D L + WAL+ ++ G + + V+ AG
Sbjct: 243 KSPPPEFAKVSPCLNVLSWLLFVSDTDVLA-DACWALSYLSDGPNDKIQAVIDAGVCRRL 301
Query: 470 LQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTW 649
++LLM V A+ A+GNI+ + ++ ++ LL L+ S + W
Sbjct: 302 VELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALQSLLHLLSSP-KESIKKEACW 360
Query: 650 VIVNL 664
I N+
Sbjct: 361 TISNI 365
Score = 43.6 bits (98), Expect = 8e-04
Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 1/102 (0%)
Frame = +2
Query: 305 DELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLM 484
D ++ ILP L+Q S+ + + WAL+N+ G S + + V LL
Sbjct: 205 DYVLDCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKSPPPEFAKVSPCLNVLSWLLF 264
Query: 485 SPHENVCDQAVWALGNIIGDGPVLR-DFVIELGVVKPLLSLI 607
+V A WAL + + DGP + VI+ GV + L+ L+
Sbjct: 265 VSDTDVLADACWAL-SYLSDGPNDKIQAVIDAGVCRRLVELL 305
Score = 39.5 bits (88), Expect = 0.012
Identities = 27/80 (33%), Positives = 38/80 (47%), Gaps = 1/80 (1%)
Frame = +2
Query: 302 IDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNK-VVHAGAVPVFLQL 478
I +I A I P L+ L A+ + E AWA+TN SG SA+ K +V G + L
Sbjct: 373 IQTVIDANIFPALISILQTAEFRTRK-EAAWAITNATSGGSAEQIKYLVELGCIKPLCDL 431
Query: 479 LMSPHENVCDQAVWALGNII 538
L + A+ L NI+
Sbjct: 432 LTVMDSKIVQVALNGLENIL 451
>BT009843-1|AAP88845.1| 536|Homo sapiens karyopherin alpha 6
(importin alpha 7) protein.
Length = 536
Score = 203 bits (495), Expect = 6e-52
Identities = 108/245 (44%), Positives = 152/245 (62%), Gaps = 9/245 (3%)
Frame = +2
Query: 17 RMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPI----SYSTDEEEIDKNL 184
RM +KN + +EMRRRR E ++LRK KRE+ L KRRNV + + D +D +
Sbjct: 13 RMKSYKNNALNPEEMRRRREEEGIQLRKQKREQQLFKRRNVELINEEAAMFDSLLMDSYV 72
Query: 185 ATTDLDELV----MNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELI-AAGILPILVQC 349
++T + ++ + +++ + QLA Q+ RKLLS + +PPIDE+I ++ V+
Sbjct: 73 SSTTGESVITREMVEMLFSDDSDLQLATTQKFRKLLSKEPSPPIDEVINTPRVVDRFVEF 132
Query: 350 LSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALG 529
L R +N LQFE AWALTNIASGTS QT V+ AGAVP+F++LL S E+V +QAVWALG
Sbjct: 133 LKRNENCTLQFEAAWALTNIASGTSQQTKIVIEAGAVPIFIELLNSDFEDVQEQAVWALG 192
Query: 530 NIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNLCRSKDPPPPLKTIQE 709
NI GD V RD+V+ ++ PLL+L+ + RN W + NLCR K+PPP +
Sbjct: 193 NIAGDSSVCRDYVLNCSILNPLLTLLTKSTRLTMTRNAVWALSNLCRGKNPPPEFAKVSP 252
Query: 710 ILPGL 724
LP L
Sbjct: 253 CLPVL 257
Score = 53.6 bits (123), Expect = 7e-07
Identities = 40/139 (28%), Positives = 60/139 (43%), Gaps = 4/139 (2%)
Frame = +2
Query: 278 LSCDKNPPIDELIAAGILPILVQCLSRAD----NPALQFETAWALTNIASGTSAQTNKVV 445
LS N I +I +G+ LV+ L D +PAL+ A+ NI +G QT ++
Sbjct: 279 LSDGPNEKIQAVIDSGVCRRLVELLMHNDYKVASPALR-----AVGNIVTGDDIQTQVIL 333
Query: 446 HAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPI 625
+ A+P L LL SP E++ +A W + NI VI+ + P+L I
Sbjct: 334 NCSALPCLLHLLSSPKESIRKEACWTISNITAGNRAQIQAVIDANIF-PVLIEILQKAEF 392
Query: 626 PFLRNVTWVIVNLCRSKDP 682
+ W I N P
Sbjct: 393 RTRKEAAWAITNATSGGTP 411
Score = 52.0 bits (119), Expect = 2e-06
Identities = 34/126 (26%), Positives = 60/126 (47%), Gaps = 1/126 (0%)
Frame = +2
Query: 290 KNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVF 469
KNPP + + LP+L + L +D+ L + WAL+ ++ G + + V+ +G
Sbjct: 241 KNPPPEFAKVSPCLPVLSRLLFSSDSDLLA-DACWALSYLSDGPNEKIQAVIDSGVCRRL 299
Query: 470 LQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLR-NVT 646
++LLM V A+ A+GNI+ + ++ + LL L+ S P +R
Sbjct: 300 VELLMHNDYKVASPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSS--PKESIRKEAC 357
Query: 647 WVIVNL 664
W I N+
Sbjct: 358 WTISNI 363
Score = 43.2 bits (97), Expect = 0.001
Identities = 28/102 (27%), Positives = 50/102 (49%), Gaps = 1/102 (0%)
Frame = +2
Query: 305 DELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLM 484
D ++ IL L+ L+++ + WAL+N+ G + + +PV +LL
Sbjct: 203 DYVLNCSILNPLLTLLTKSTRLTMTRNAVWALSNLCRGKNPPPEFAKVSPCLPVLSRLLF 262
Query: 485 SPHENVCDQAVWALGNIIGDGPVLR-DFVIELGVVKPLLSLI 607
S ++ A WAL + + DGP + VI+ GV + L+ L+
Sbjct: 263 SSDSDLLADACWAL-SYLSDGPNEKIQAVIDSGVCRRLVELL 303
>BC020520-1|AAH20520.1| 536|Homo sapiens karyopherin alpha 6
(importin alpha 7) protein.
Length = 536
Score = 203 bits (495), Expect = 6e-52
Identities = 108/245 (44%), Positives = 152/245 (62%), Gaps = 9/245 (3%)
Frame = +2
Query: 17 RMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPI----SYSTDEEEIDKNL 184
RM +KN + +EMRRRR E ++LRK KRE+ L KRRNV + + D +D +
Sbjct: 13 RMKSYKNNALNPEEMRRRREEEGIQLRKQKREQQLFKRRNVELINEEAAMFDSLLMDSYV 72
Query: 185 ATTDLDELV----MNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELI-AAGILPILVQC 349
++T + ++ + +++ + QLA Q+ RKLLS + +PPIDE+I ++ V+
Sbjct: 73 SSTTGESVITREMVEMLFSDDSDLQLATTQKFRKLLSKEPSPPIDEVINTPRVVDRFVEF 132
Query: 350 LSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALG 529
L R +N LQFE AWALTNIASGTS QT V+ AGAVP+F++LL S E+V +QAVWALG
Sbjct: 133 LKRNENCTLQFEAAWALTNIASGTSQQTKIVIEAGAVPIFIELLNSDFEDVQEQAVWALG 192
Query: 530 NIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNLCRSKDPPPPLKTIQE 709
NI GD V RD+V+ ++ PLL+L+ + RN W + NLCR K+PPP +
Sbjct: 193 NIAGDSSVCRDYVLNCSILNPLLTLLTKSTRLTMTRNAVWALSNLCRGKNPPPEFAKVSP 252
Query: 710 ILPGL 724
LP L
Sbjct: 253 CLPVL 257
Score = 53.6 bits (123), Expect = 7e-07
Identities = 40/139 (28%), Positives = 60/139 (43%), Gaps = 4/139 (2%)
Frame = +2
Query: 278 LSCDKNPPIDELIAAGILPILVQCLSRAD----NPALQFETAWALTNIASGTSAQTNKVV 445
LS N I +I +G+ LV+ L D +PAL+ A+ NI +G QT ++
Sbjct: 279 LSDGPNEKIQAVIDSGVCRRLVELLMHNDYKVASPALR-----AVGNIVTGDDIQTQVIL 333
Query: 446 HAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPI 625
+ A+P L LL SP E++ +A W + NI VI+ + P+L I
Sbjct: 334 NCSALPCLLHLLSSPKESIRKEACWTISNITAGNRAQIQAVIDANIF-PVLIEILQKAEF 392
Query: 626 PFLRNVTWVIVNLCRSKDP 682
+ W I N P
Sbjct: 393 RTRKEAAWAITNATSGGTP 411
Score = 52.0 bits (119), Expect = 2e-06
Identities = 34/126 (26%), Positives = 60/126 (47%), Gaps = 1/126 (0%)
Frame = +2
Query: 290 KNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVF 469
KNPP + + LP+L + L +D+ L + WAL+ ++ G + + V+ +G
Sbjct: 241 KNPPPEFAKVSPCLPVLSRLLFSSDSDLLA-DACWALSYLSDGPNEKIQAVIDSGVCRRL 299
Query: 470 LQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLR-NVT 646
++LLM V A+ A+GNI+ + ++ + LL L+ S P +R
Sbjct: 300 VELLMHNDYKVASPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSS--PKESIRKEAC 357
Query: 647 WVIVNL 664
W I N+
Sbjct: 358 WTISNI 363
Score = 43.2 bits (97), Expect = 0.001
Identities = 28/102 (27%), Positives = 50/102 (49%), Gaps = 1/102 (0%)
Frame = +2
Query: 305 DELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLM 484
D ++ IL L+ L+++ + WAL+N+ G + + +PV +LL
Sbjct: 203 DYVLNCSILNPLLTLLTKSTRLTMTRNAVWALSNLCRGKNPPPEFAKVSPCLPVLSRLLF 262
Query: 485 SPHENVCDQAVWALGNIIGDGPVLR-DFVIELGVVKPLLSLI 607
S ++ A WAL + + DGP + VI+ GV + L+ L+
Sbjct: 263 SSDSDLLADACWAL-SYLSDGPNEKIQAVIDSGVCRRLVELL 303
>AL445248-5|CAH71948.1| 536|Homo sapiens karyopherin alpha 6
(importin alpha 7) protein.
Length = 536
Score = 203 bits (495), Expect = 6e-52
Identities = 108/245 (44%), Positives = 152/245 (62%), Gaps = 9/245 (3%)
Frame = +2
Query: 17 RMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPI----SYSTDEEEIDKNL 184
RM +KN + +EMRRRR E ++LRK KRE+ L KRRNV + + D +D +
Sbjct: 13 RMKSYKNNALNPEEMRRRREEEGIQLRKQKREQQLFKRRNVELINEEAAMFDSLLMDSYV 72
Query: 185 ATTDLDELV----MNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELI-AAGILPILVQC 349
++T + ++ + +++ + QLA Q+ RKLLS + +PPIDE+I ++ V+
Sbjct: 73 SSTTGESVITREMVEMLFSDDSDLQLATTQKFRKLLSKEPSPPIDEVINTPRVVDRFVEF 132
Query: 350 LSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALG 529
L R +N LQFE AWALTNIASGTS QT V+ AGAVP+F++LL S E+V +QAVWALG
Sbjct: 133 LKRNENCTLQFEAAWALTNIASGTSQQTKIVIEAGAVPIFIELLNSDFEDVQEQAVWALG 192
Query: 530 NIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNLCRSKDPPPPLKTIQE 709
NI GD V RD+V+ ++ PLL+L+ + RN W + NLCR K+PPP +
Sbjct: 193 NIAGDSSVCRDYVLNCSILNPLLTLLTKSTRLTMTRNAVWALSNLCRGKNPPPEFAKVSP 252
Query: 710 ILPGL 724
LP L
Sbjct: 253 CLPVL 257
Score = 53.6 bits (123), Expect = 7e-07
Identities = 40/139 (28%), Positives = 60/139 (43%), Gaps = 4/139 (2%)
Frame = +2
Query: 278 LSCDKNPPIDELIAAGILPILVQCLSRAD----NPALQFETAWALTNIASGTSAQTNKVV 445
LS N I +I +G+ LV+ L D +PAL+ A+ NI +G QT ++
Sbjct: 279 LSDGPNEKIQAVIDSGVCRRLVELLMHNDYKVASPALR-----AVGNIVTGDDIQTQVIL 333
Query: 446 HAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPI 625
+ A+P L LL SP E++ +A W + NI VI+ + P+L I
Sbjct: 334 NCSALPCLLHLLSSPKESIRKEACWTISNITAGNRAQIQAVIDANIF-PVLIEILQKAEF 392
Query: 626 PFLRNVTWVIVNLCRSKDP 682
+ W I N P
Sbjct: 393 RTRKEAAWAITNATSGGTP 411
Score = 52.0 bits (119), Expect = 2e-06
Identities = 34/126 (26%), Positives = 60/126 (47%), Gaps = 1/126 (0%)
Frame = +2
Query: 290 KNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVF 469
KNPP + + LP+L + L +D+ L + WAL+ ++ G + + V+ +G
Sbjct: 241 KNPPPEFAKVSPCLPVLSRLLFSSDSDLLA-DACWALSYLSDGPNEKIQAVIDSGVCRRL 299
Query: 470 LQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLR-NVT 646
++LLM V A+ A+GNI+ + ++ + LL L+ S P +R
Sbjct: 300 VELLMHNDYKVASPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSS--PKESIRKEAC 357
Query: 647 WVIVNL 664
W I N+
Sbjct: 358 WTISNI 363
Score = 43.2 bits (97), Expect = 0.001
Identities = 28/102 (27%), Positives = 50/102 (49%), Gaps = 1/102 (0%)
Frame = +2
Query: 305 DELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLM 484
D ++ IL L+ L+++ + WAL+N+ G + + +PV +LL
Sbjct: 203 DYVLNCSILNPLLTLLTKSTRLTMTRNAVWALSNLCRGKNPPPEFAKVSPCLPVLSRLLF 262
Query: 485 SPHENVCDQAVWALGNIIGDGPVLR-DFVIELGVVKPLLSLI 607
S ++ A WAL + + DGP + VI+ GV + L+ L+
Sbjct: 263 SSDSDLLADACWAL-SYLSDGPNEKIQAVIDSGVCRRLVELL 303
>AL049795-3|CAI22056.1| 536|Homo sapiens karyopherin alpha 6
(importin alpha 7) protein.
Length = 536
Score = 203 bits (495), Expect = 6e-52
Identities = 108/245 (44%), Positives = 152/245 (62%), Gaps = 9/245 (3%)
Frame = +2
Query: 17 RMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPI----SYSTDEEEIDKNL 184
RM +KN + +EMRRRR E ++LRK KRE+ L KRRNV + + D +D +
Sbjct: 13 RMKSYKNNALNPEEMRRRREEEGIQLRKQKREQQLFKRRNVELINEEAAMFDSLLMDSYV 72
Query: 185 ATTDLDELV----MNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELI-AAGILPILVQC 349
++T + ++ + +++ + QLA Q+ RKLLS + +PPIDE+I ++ V+
Sbjct: 73 SSTTGESVITREMVEMLFSDDSDLQLATTQKFRKLLSKEPSPPIDEVINTPRVVDRFVEF 132
Query: 350 LSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALG 529
L R +N LQFE AWALTNIASGTS QT V+ AGAVP+F++LL S E+V +QAVWALG
Sbjct: 133 LKRNENCTLQFEAAWALTNIASGTSQQTKIVIEAGAVPIFIELLNSDFEDVQEQAVWALG 192
Query: 530 NIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNLCRSKDPPPPLKTIQE 709
NI GD V RD+V+ ++ PLL+L+ + RN W + NLCR K+PPP +
Sbjct: 193 NIAGDSSVCRDYVLNCSILNPLLTLLTKSTRLTMTRNAVWALSNLCRGKNPPPEFAKVSP 252
Query: 710 ILPGL 724
LP L
Sbjct: 253 CLPVL 257
Score = 53.6 bits (123), Expect = 7e-07
Identities = 40/139 (28%), Positives = 60/139 (43%), Gaps = 4/139 (2%)
Frame = +2
Query: 278 LSCDKNPPIDELIAAGILPILVQCLSRAD----NPALQFETAWALTNIASGTSAQTNKVV 445
LS N I +I +G+ LV+ L D +PAL+ A+ NI +G QT ++
Sbjct: 279 LSDGPNEKIQAVIDSGVCRRLVELLMHNDYKVASPALR-----AVGNIVTGDDIQTQVIL 333
Query: 446 HAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPI 625
+ A+P L LL SP E++ +A W + NI VI+ + P+L I
Sbjct: 334 NCSALPCLLHLLSSPKESIRKEACWTISNITAGNRAQIQAVIDANIF-PVLIEILQKAEF 392
Query: 626 PFLRNVTWVIVNLCRSKDP 682
+ W I N P
Sbjct: 393 RTRKEAAWAITNATSGGTP 411
Score = 52.0 bits (119), Expect = 2e-06
Identities = 34/126 (26%), Positives = 60/126 (47%), Gaps = 1/126 (0%)
Frame = +2
Query: 290 KNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVF 469
KNPP + + LP+L + L +D+ L + WAL+ ++ G + + V+ +G
Sbjct: 241 KNPPPEFAKVSPCLPVLSRLLFSSDSDLLA-DACWALSYLSDGPNEKIQAVIDSGVCRRL 299
Query: 470 LQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLR-NVT 646
++LLM V A+ A+GNI+ + ++ + LL L+ S P +R
Sbjct: 300 VELLMHNDYKVASPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSS--PKESIRKEAC 357
Query: 647 WVIVNL 664
W I N+
Sbjct: 358 WTISNI 363
Score = 43.2 bits (97), Expect = 0.001
Identities = 28/102 (27%), Positives = 50/102 (49%), Gaps = 1/102 (0%)
Frame = +2
Query: 305 DELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLM 484
D ++ IL L+ L+++ + WAL+N+ G + + +PV +LL
Sbjct: 203 DYVLNCSILNPLLTLLTKSTRLTMTRNAVWALSNLCRGKNPPPEFAKVSPCLPVLSRLLF 262
Query: 485 SPHENVCDQAVWALGNIIGDGPVLR-DFVIELGVVKPLLSLI 607
S ++ A WAL + + DGP + VI+ GV + L+ L+
Sbjct: 263 SSDSDLLADACWAL-SYLSDGPNEKIQAVIDSGVCRRLVELL 303
>AF060543-1|AAC15233.1| 536|Homo sapiens importin alpha 7 subunit
protein.
Length = 536
Score = 203 bits (495), Expect = 6e-52
Identities = 108/245 (44%), Positives = 152/245 (62%), Gaps = 9/245 (3%)
Frame = +2
Query: 17 RMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPI----SYSTDEEEIDKNL 184
RM +KN + +EMRRRR E ++LRK KRE+ L KRRNV + + D +D +
Sbjct: 13 RMKSYKNNALNPEEMRRRREEEGIQLRKQKREQQLFKRRNVELINEEAAMFDSLLMDSYV 72
Query: 185 ATTDLDELV----MNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELI-AAGILPILVQC 349
++T + ++ + +++ + QLA Q+ RKLLS + +PPIDE+I ++ V+
Sbjct: 73 SSTTGESVITREMVEMLFSDDSDLQLATTQKFRKLLSKEPSPPIDEVINTPRVVDRFVEF 132
Query: 350 LSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALG 529
L R +N LQFE AWALTNIASGTS QT V+ AGAVP+F++LL S E+V +QAVWALG
Sbjct: 133 LKRNENCTLQFEAAWALTNIASGTSQQTKIVIEAGAVPIFIELLNSDFEDVQEQAVWALG 192
Query: 530 NIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNLCRSKDPPPPLKTIQE 709
NI GD V RD+V+ ++ PLL+L+ + RN W + NLCR K+PPP +
Sbjct: 193 NIAGDSSVCRDYVLNCSILNPLLTLLTKSTRLTMTRNAVWALSNLCRGKNPPPEFAKVSP 252
Query: 710 ILPGL 724
LP L
Sbjct: 253 CLPVL 257
Score = 53.6 bits (123), Expect = 7e-07
Identities = 40/139 (28%), Positives = 60/139 (43%), Gaps = 4/139 (2%)
Frame = +2
Query: 278 LSCDKNPPIDELIAAGILPILVQCLSRAD----NPALQFETAWALTNIASGTSAQTNKVV 445
LS N I +I +G+ LV+ L D +PAL+ A+ NI +G QT ++
Sbjct: 279 LSDGPNEKIQAVIDSGVCRRLVELLMHNDYKVASPALR-----AVGNIVTGDDIQTQVIL 333
Query: 446 HAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPI 625
+ A+P L LL SP E++ +A W + NI VI+ + P+L I
Sbjct: 334 NCSALPCLLHLLSSPKESIRKEACWTISNITAGNRAQIQAVIDANIF-PVLIEILQKAEF 392
Query: 626 PFLRNVTWVIVNLCRSKDP 682
+ W I N P
Sbjct: 393 RTRKEAAWAITNATSGGTP 411
Score = 52.0 bits (119), Expect = 2e-06
Identities = 34/126 (26%), Positives = 60/126 (47%), Gaps = 1/126 (0%)
Frame = +2
Query: 290 KNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVF 469
KNPP + + LP+L + L +D+ L + WAL+ ++ G + + V+ +G
Sbjct: 241 KNPPPEFAKVSPCLPVLSRLLFSSDSDLLA-DACWALSYLSDGPNEKIQAVIDSGVCRRL 299
Query: 470 LQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLR-NVT 646
++LLM V A+ A+GNI+ + ++ + LL L+ S P +R
Sbjct: 300 VELLMHNDYKVASPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSS--PKESIRKEAC 357
Query: 647 WVIVNL 664
W I N+
Sbjct: 358 WTISNI 363
Score = 43.2 bits (97), Expect = 0.001
Identities = 28/102 (27%), Positives = 50/102 (49%), Gaps = 1/102 (0%)
Frame = +2
Query: 305 DELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLM 484
D ++ IL L+ L+++ + WAL+N+ G + + +PV +LL
Sbjct: 203 DYVLNCSILNPLLTLLTKSTRLTMTRNAVWALSNLCRGKNPPPEFAKVSPCLPVLSRLLF 262
Query: 485 SPHENVCDQAVWALGNIIGDGPVLR-DFVIELGVVKPLLSLI 607
S ++ A WAL + + DGP + VI+ GV + L+ L+
Sbjct: 263 SSDSDLLADACWAL-SYLSDGPNEKIQAVIDSGVCRRLVELL 303
>AF005361-1|AAC51868.1| 536|Homo sapiens importin alpha 6 protein.
Length = 536
Score = 198 bits (483), Expect = 2e-50
Identities = 108/246 (43%), Positives = 145/246 (58%), Gaps = 13/246 (5%)
Frame = +2
Query: 17 RMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYSTDEEEIDKNLATTD 196
RM +KN + EMRRRR E ++LRK KREE L KRRNV + + DE ++ + +D
Sbjct: 10 RMKSYKNKALNPQEMRRRREEEGIQLRKQKREEQLFKRRNVYLPRN-DESMLESPIQDSD 68
Query: 197 LDELV------------MNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELIAA-GILPI 337
+ V + + N + QL A Q+ RKLLS + NPPID++I G++
Sbjct: 69 ISSTVPIPEEGVVTTDMVQMIFSNNADQQLTATQKFRKLLSKEPNPPIDQVIQKPGVVQR 128
Query: 338 LVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAV 517
V+ L R +N LQFE AWALTNIASGT T V+ GAVP+F++LL S HE+V +QAV
Sbjct: 129 FVKFLERNENCTLQFEAAWALTNIASGTFLHTKVVIETGAVPIFIKLLNSEHEDVQEQAV 188
Query: 518 WALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNLCRSKDPPPPLK 697
WALGNI GD RDFV+ ++ PLL L+ + + RN W + NLCR K+PPP
Sbjct: 189 WALGNIAGDNAECRDFVLNCEILPPLLELLTNSNRLTTTRNAVWALSNLCRGKNPPPNFS 248
Query: 698 TIQEIL 715
+ L
Sbjct: 249 KVSPCL 254
Score = 54.4 bits (125), Expect = 4e-07
Identities = 40/145 (27%), Positives = 59/145 (40%)
Frame = +2
Query: 248 LAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSA 427
LA V LS N I +I +G+ LV+ L D + A+ NI +G
Sbjct: 269 LADVCWALSYLSDGPNDKIQAVIDSGVCRRLVELLMHNDYKVVS-PALRAVGNIVTGDDI 327
Query: 428 QTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLI 607
QT +++ A+P L LL SP E++ +A W + NI VI+ + P+L I
Sbjct: 328 QTQVILNCSALPCLLHLLSSPKESIRKEACWTVSNITAGNRAQIQAVIDANIF-PVLIEI 386
Query: 608 KSDIPIPFLRNVTWVIVNLCRSKDP 682
+ W I N P
Sbjct: 387 LQKAEFRTRKEAAWAITNATSGGTP 411
Score = 46.4 bits (105), Expect = 1e-04
Identities = 32/126 (25%), Positives = 59/126 (46%), Gaps = 1/126 (0%)
Frame = +2
Query: 290 KNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVF 469
KNPP + + L +L + L +D P + + WAL+ ++ G + + V+ +G
Sbjct: 241 KNPPPNFSKVSPCLNVLSRLLFSSD-PDVLADVCWALSYLSDGPNDKIQAVIDSGVCRRL 299
Query: 470 LQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLR-NVT 646
++LLM V A+ A+GNI+ + ++ + LL L+ S P +R
Sbjct: 300 VELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSS--PKESIRKEAC 357
Query: 647 WVIVNL 664
W + N+
Sbjct: 358 WTVSNI 363
Score = 44.0 bits (99), Expect = 6e-04
Identities = 35/129 (27%), Positives = 60/129 (46%), Gaps = 1/129 (0%)
Frame = +2
Query: 224 NAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAWALT 403
N+E+ + Q AV + D D ++ ILP L++ L+ ++ WAL+
Sbjct: 177 NSEHEDVQEQAVWALGNIAG-DNAECRDFVLNCEILPPLLELLTNSNRLTTTRNAVWALS 235
Query: 404 NIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLR-DFVIELG 580
N+ G + N + + V +LL S +V WAL + + DGP + VI+ G
Sbjct: 236 NLCRGKNPPPNFSKVSPCLNVLSRLLFSSDPDVLADVCWAL-SYLSDGPNDKIQAVIDSG 294
Query: 581 VVKPLLSLI 607
V + L+ L+
Sbjct: 295 VCRRLVELL 303
>BC047409-1|AAH47409.1| 539|Homo sapiens karyopherin alpha 5
(importin alpha 6) protein.
Length = 539
Score = 197 bits (481), Expect = 3e-50
Identities = 108/246 (43%), Positives = 143/246 (58%), Gaps = 13/246 (5%)
Frame = +2
Query: 17 RMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYSTDEEEIDKNLATTD 196
RM +KN + EMRRRR E ++LRK KREE L KRRNV + DE ++ + D
Sbjct: 13 RMKSYKNKALNPQEMRRRREEEGIQLRKQKREEQLFKRRNVYLP-RNDESMLESPIQDPD 71
Query: 197 LDELV------------MNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELI-AAGILPI 337
+ V + + N + QL A Q+ RKLLS + NPPID++I G++
Sbjct: 72 ISSTVPIPEEEVVTTDMVQMIFSNNADQQLTATQKFRKLLSKEPNPPIDQVIQKPGVVQR 131
Query: 338 LVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAV 517
V+ L R +N LQFE AWALTNIASGT T V+ GAVP+F++LL S HE+V +QAV
Sbjct: 132 FVKFLERNENCTLQFEAAWALTNIASGTFLHTKVVIETGAVPIFIKLLNSEHEDVQEQAV 191
Query: 518 WALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNLCRSKDPPPPLK 697
WALGNI GD RDFV+ ++ PLL L+ + + RN W + NLCR K+PPP
Sbjct: 192 WALGNIAGDNAECRDFVLNCEILPPLLELLTNSNRLTTTRNAVWALSNLCRGKNPPPNFS 251
Query: 698 TIQEIL 715
+ L
Sbjct: 252 KVSPCL 257
Score = 54.4 bits (125), Expect = 4e-07
Identities = 40/145 (27%), Positives = 59/145 (40%)
Frame = +2
Query: 248 LAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSA 427
LA V LS N I +I +G+ LV+ L D + A+ NI +G
Sbjct: 272 LADVCWALSYLSDGPNDKIQAVIDSGVCRRLVELLMHNDYKVVS-PALRAVGNIVTGDDI 330
Query: 428 QTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLI 607
QT +++ A+P L LL SP E++ +A W + NI VI+ + P+L I
Sbjct: 331 QTQVILNCSALPCLLHLLSSPKESIRKEACWTVSNITAGNRAQIQAVIDANIF-PVLIEI 389
Query: 608 KSDIPIPFLRNVTWVIVNLCRSKDP 682
+ W I N P
Sbjct: 390 LQKAEFRTRKEAAWAITNATSGGTP 414
Score = 46.4 bits (105), Expect = 1e-04
Identities = 32/126 (25%), Positives = 59/126 (46%), Gaps = 1/126 (0%)
Frame = +2
Query: 290 KNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVF 469
KNPP + + L +L + L +D P + + WAL+ ++ G + + V+ +G
Sbjct: 244 KNPPPNFSKVSPCLNVLSRLLFSSD-PDVLADVCWALSYLSDGPNDKIQAVIDSGVCRRL 302
Query: 470 LQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLR-NVT 646
++LLM V A+ A+GNI+ + ++ + LL L+ S P +R
Sbjct: 303 VELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSS--PKESIRKEAC 360
Query: 647 WVIVNL 664
W + N+
Sbjct: 361 WTVSNI 366
Score = 44.0 bits (99), Expect = 6e-04
Identities = 35/129 (27%), Positives = 60/129 (46%), Gaps = 1/129 (0%)
Frame = +2
Query: 224 NAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAWALT 403
N+E+ + Q AV + D D ++ ILP L++ L+ ++ WAL+
Sbjct: 180 NSEHEDVQEQAVWALGNIAG-DNAECRDFVLNCEILPPLLELLTNSNRLTTTRNAVWALS 238
Query: 404 NIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLR-DFVIELG 580
N+ G + N + + V +LL S +V WAL + + DGP + VI+ G
Sbjct: 239 NLCRGKNPPPNFSKVSPCLNVLSRLLFSSDPDVLADVCWAL-SYLSDGPNDKIQAVIDSG 297
Query: 581 VVKPLLSLI 607
V + L+ L+
Sbjct: 298 VCRRLVELL 306
>AL132795-5|CAI20500.1| 539|Homo sapiens karyopherin alpha 5
(importin alpha 6) protein.
Length = 539
Score = 197 bits (481), Expect = 3e-50
Identities = 108/246 (43%), Positives = 143/246 (58%), Gaps = 13/246 (5%)
Frame = +2
Query: 17 RMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYSTDEEEIDKNLATTD 196
RM +KN + EMRRRR E ++LRK KREE L KRRNV + DE ++ + D
Sbjct: 13 RMKSYKNKALNPQEMRRRREEEGIQLRKQKREEQLFKRRNVYLP-RNDESMLESPIQDPD 71
Query: 197 LDELV------------MNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELI-AAGILPI 337
+ V + + N + QL A Q+ RKLLS + NPPID++I G++
Sbjct: 72 ISSTVPIPEEEVVTTDMVQMIFSNNADQQLTATQKFRKLLSKEPNPPIDQVIQKPGVVQR 131
Query: 338 LVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAV 517
V+ L R +N LQFE AWALTNIASGT T V+ GAVP+F++LL S HE+V +QAV
Sbjct: 132 FVKFLERNENCTLQFEAAWALTNIASGTFLHTKVVIETGAVPIFIKLLNSEHEDVQEQAV 191
Query: 518 WALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNLCRSKDPPPPLK 697
WALGNI GD RDFV+ ++ PLL L+ + + RN W + NLCR K+PPP
Sbjct: 192 WALGNIAGDNAECRDFVLNCEILPPLLELLTNSNRLTTTRNAVWALSNLCRGKNPPPNFS 251
Query: 698 TIQEIL 715
+ L
Sbjct: 252 KVSPCL 257
Score = 54.4 bits (125), Expect = 4e-07
Identities = 40/145 (27%), Positives = 59/145 (40%)
Frame = +2
Query: 248 LAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSA 427
LA V LS N I +I +G+ LV+ L D + A+ NI +G
Sbjct: 272 LADVCWALSYLSDGPNDKIQAVIDSGVCRRLVELLMHNDYKVVS-PALRAVGNIVTGDDI 330
Query: 428 QTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLI 607
QT +++ A+P L LL SP E++ +A W + NI VI+ + P+L I
Sbjct: 331 QTQVILNCSALPCLLHLLSSPKESIRKEACWTVSNITAGNRAQIQAVIDANIF-PVLIEI 389
Query: 608 KSDIPIPFLRNVTWVIVNLCRSKDP 682
+ W I N P
Sbjct: 390 LQKAEFRTRKEAAWAITNATSGGTP 414
Score = 46.4 bits (105), Expect = 1e-04
Identities = 32/126 (25%), Positives = 59/126 (46%), Gaps = 1/126 (0%)
Frame = +2
Query: 290 KNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVF 469
KNPP + + L +L + L +D P + + WAL+ ++ G + + V+ +G
Sbjct: 244 KNPPPNFSKVSPCLNVLSRLLFSSD-PDVLADVCWALSYLSDGPNDKIQAVIDSGVCRRL 302
Query: 470 LQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLR-NVT 646
++LLM V A+ A+GNI+ + ++ + LL L+ S P +R
Sbjct: 303 VELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSS--PKESIRKEAC 360
Query: 647 WVIVNL 664
W + N+
Sbjct: 361 WTVSNI 366
Score = 44.0 bits (99), Expect = 6e-04
Identities = 35/129 (27%), Positives = 60/129 (46%), Gaps = 1/129 (0%)
Frame = +2
Query: 224 NAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAWALT 403
N+E+ + Q AV + D D ++ ILP L++ L+ ++ WAL+
Sbjct: 180 NSEHEDVQEQAVWALGNIAG-DNAECRDFVLNCEILPPLLELLTNSNRLTTTRNAVWALS 238
Query: 404 NIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLR-DFVIELG 580
N+ G + N + + V +LL S +V WAL + + DGP + VI+ G
Sbjct: 239 NLCRGKNPPPNFSKVSPCLNVLSRLLFSSDPDVLADVCWAL-SYLSDGPNDKIQAVIDSG 297
Query: 581 VVKPLLSLI 607
V + L+ L+
Sbjct: 298 VCRRLVELL 306
>AL049795-1|CAI22054.1| 321|Homo sapiens karyopherin alpha 6
(importin alpha 7) protein.
Length = 321
Score = 82.6 bits (195), Expect = 1e-15
Identities = 43/123 (34%), Positives = 62/123 (50%), Gaps = 1/123 (0%)
Frame = +2
Query: 359 ADNPALQFETAWALTNIASGT-SAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNI 535
+D+ LQ T + S S ++V++ V + +EN QAVWALGNI
Sbjct: 42 SDDSDLQLATTQKFRKLLSKEPSPPIDEVINTPRVVDRFVEFLKRNENCTLQAVWALGNI 101
Query: 536 IGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNLCRSKDPPPPLKTIQEIL 715
GD V RD+V+ ++ PLL+L+ + RN W + NLCR K+PPP + L
Sbjct: 102 AGDSSVCRDYVLNCSILNPLLTLLTKSTRLTMTRNAVWALSNLCRGKNPPPEFAKVSPCL 161
Query: 716 PGL 724
P L
Sbjct: 162 PVL 164
Score = 60.5 bits (140), Expect = 6e-09
Identities = 44/145 (30%), Positives = 71/145 (48%), Gaps = 2/145 (1%)
Frame = +2
Query: 227 AENPEAQLAAVQQCRKLLSCDKNPPIDELI-AAGILPILVQCLSRADNPALQFETAWALT 403
+++ + QLA Q+ RKLLS + +PPIDE+I ++ V+ L R +N LQ WAL
Sbjct: 42 SDDSDLQLATTQKFRKLLSKEPSPPIDEVINTPRVVDRFVEFLKRNENCTLQ--AVWALG 99
Query: 404 NIASGTSAQTNKVVHAGAV-PVFLQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELG 580
NIA +S + V++ + P+ L S + AVWAL N+ +F ++
Sbjct: 100 NIAGDSSVCRDYVLNCSILNPLLTLLTKSTRLTMTRNAVWALSNLCRGKNPPPEFA-KVS 158
Query: 581 VVKPLLSLIKSDIPIPFLRNVTWVI 655
P+LS + L + W +
Sbjct: 159 PCLPVLSRLLFSSDSDLLADACWAL 183
Score = 53.6 bits (123), Expect = 7e-07
Identities = 40/139 (28%), Positives = 60/139 (43%), Gaps = 4/139 (2%)
Frame = +2
Query: 278 LSCDKNPPIDELIAAGILPILVQCLSRAD----NPALQFETAWALTNIASGTSAQTNKVV 445
LS N I +I +G+ LV+ L D +PAL+ A+ NI +G QT ++
Sbjct: 186 LSDGPNEKIQAVIDSGVCRRLVELLMHNDYKVASPALR-----AVGNIVTGDDIQTQVIL 240
Query: 446 HAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPI 625
+ A+P L LL SP E++ +A W + NI VI+ + P+L I
Sbjct: 241 NCSALPCLLHLLSSPKESIRKEACWTISNITAGNRAQIQAVIDANIF-PVLIEILQKAEF 299
Query: 626 PFLRNVTWVIVNLCRSKDP 682
+ W I N P
Sbjct: 300 RTRKEAAWAITNATSGGTP 318
Score = 52.0 bits (119), Expect = 2e-06
Identities = 34/126 (26%), Positives = 60/126 (47%), Gaps = 1/126 (0%)
Frame = +2
Query: 290 KNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVF 469
KNPP + + LP+L + L +D+ L + WAL+ ++ G + + V+ +G
Sbjct: 148 KNPPPEFAKVSPCLPVLSRLLFSSDSDLLA-DACWALSYLSDGPNEKIQAVIDSGVCRRL 206
Query: 470 LQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPFLR-NVT 646
++LLM V A+ A+GNI+ + ++ + LL L+ S P +R
Sbjct: 207 VELLMHNDYKVASPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSS--PKESIRKEAC 264
Query: 647 WVIVNL 664
W I N+
Sbjct: 265 WTISNI 270
>AL132795-6|CAI20501.1| 142|Homo sapiens karyopherin alpha 5
(importin alpha 6) protein.
Length = 142
Score = 76.6 bits (180), Expect = 9e-14
Identities = 51/134 (38%), Positives = 71/134 (52%), Gaps = 13/134 (9%)
Frame = +2
Query: 17 RMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYSTDEEEIDKNLATTD 196
RM +KN + EMRRRR E ++LRK KREE L KRRNV + DE ++ + D
Sbjct: 10 RMKSYKNKALNPQEMRRRREEEGIQLRKQKREEQLFKRRNVYLP-RNDESMLESPIQDPD 68
Query: 197 LDELV------------MNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELI-AAGILPI 337
+ V + + N + QL A Q+ RKLLS + NPPID++I G++
Sbjct: 69 ISSTVPIPEEEVVTTDMVQMIFSNNADQQLTATQKFRKLLSKEPNPPIDQVIQKPGVVQR 128
Query: 338 LVQCLSRADNPALQ 379
V+ L R +N LQ
Sbjct: 129 FVKFLERNENCTLQ 142
>Y12393-1|CAA73025.1| 281|Homo sapiens SRP1-like protein protein.
Length = 281
Score = 56.4 bits (130), Expect = 1e-07
Identities = 41/125 (32%), Positives = 59/125 (47%), Gaps = 1/125 (0%)
Frame = +2
Query: 293 NPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFL 472
N I +I +GI+P LV LS + +Q A+ NI +GT QT V++ A+ F
Sbjct: 34 NEQIQMVIDSGIVPHLVPLLSHQE-VKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFP 92
Query: 473 QLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLI-KSDIPIPFLRNVTW 649
LL P E + +AVW L NI VI+ +V ++ L+ K D + W
Sbjct: 93 ALLTHPKEKINKEAVWFLSNITAGNQQQVQAVIDANLVPMIIHLLDKGDFGTQ--KEAAW 150
Query: 650 VIVNL 664
I NL
Sbjct: 151 AISNL 155
Score = 42.7 bits (96), Expect = 0.001
Identities = 22/76 (28%), Positives = 37/76 (48%), Gaps = 1/76 (1%)
Frame = +2
Query: 383 ETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLR- 559
E W L+NI +G Q V+ A VP+ + LL +A WA+ N+ G +
Sbjct: 105 EAVWFLSNITAGNQQQVQAVIDANLVPMIIHLLDKGDFGTQKEAAWAISNLTISGRKDQV 164
Query: 560 DFVIELGVVKPLLSLI 607
++I+ V+ P +L+
Sbjct: 165 AYLIQQNVIPPFCNLL 180
>BC030585-1|AAH30585.1| 458|Homo sapiens sperm associated antigen 6
protein.
Length = 458
Score = 52.4 bits (120), Expect = 2e-06
Identities = 33/99 (33%), Positives = 48/99 (48%)
Frame = +2
Query: 311 LIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSP 490
++ G L LV CL D P ++ AWAL IA + + VV AGAVP+ + + P
Sbjct: 121 IVDCGALDTLVICLEDFD-PGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEP 179
Query: 491 HENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLI 607
+ A AL +I+ P L V++ G V L +I
Sbjct: 180 EIALKGIAASALSDIVKHSPELAQTVVDAGAVAHLAQMI 218
Score = 44.0 bits (99), Expect = 6e-04
Identities = 28/100 (28%), Positives = 51/100 (51%)
Frame = +2
Query: 311 LIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSP 490
++ AG +P+LV C+ + AL+ A AL++I + VV AGAV Q++++P
Sbjct: 163 VVDAGAVPLLVLCIQEPEI-ALKGIAASALSDIVKHSPELAQTVVDAGAVAHLAQMILNP 221
Query: 491 HENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIK 610
+ Q + AL + L + V+E + +L+ +K
Sbjct: 222 DAKLKHQILSALSQVSKHSVDLAEMVVEAEIFPVVLTCLK 261
Score = 34.7 bits (76), Expect = 0.35
Identities = 33/121 (27%), Positives = 49/121 (40%), Gaps = 9/121 (7%)
Frame = +2
Query: 152 STDEEEIDKNLATTDLDELVMNAANAE---------NPEAQLAAVQQCRKLLSCDKNPPI 304
ST EI K+ T +L +LV+NA +L + + + +N +
Sbjct: 272 STLIREIAKH--TPELSQLVVNAGGVAAVIDCIGSCKGNTRLPGIMMLGYVAAHSENLAM 329
Query: 305 DELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLM 484
+I+ G+ P L CLS ++ AWAL I T V +PV L L M
Sbjct: 330 AVIISKGV-PQLSVCLSEEPEDHIKAAAAWALGQIGRHTPEHARAVAVTNTLPVLLSLYM 388
Query: 485 S 487
S
Sbjct: 389 S 389
>CR533552-1|CAG38583.1| 509|Homo sapiens SPAG6 protein.
Length = 509
Score = 50.4 bits (115), Expect = 7e-06
Identities = 33/99 (33%), Positives = 47/99 (47%)
Frame = +2
Query: 311 LIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSP 490
++ G L LV CL D P ++ AWAL IA + + VV AGAVP+ + + P
Sbjct: 121 IVDCGALDTLVICLEDFD-PGVKEAAAWALRYIARHNAELSRAVVDAGAVPLLVLCIQEP 179
Query: 491 HENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLI 607
+ A AL +I P L V++ G V L +I
Sbjct: 180 EIALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMI 218
Score = 45.6 bits (103), Expect = 2e-04
Identities = 29/100 (29%), Positives = 52/100 (52%)
Frame = +2
Query: 311 LIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSP 490
++ AG +P+LV C+ + AL+ A AL++IA + VV AGAV Q++++P
Sbjct: 163 VVDAGAVPLLVLCIQEPEI-ALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMILNP 221
Query: 491 HENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIK 610
+ Q + AL + L + V+E + +L+ +K
Sbjct: 222 DAKLKHQILSALSQVSKHSVDLAEMVVEAEIFPVVLTCLK 261
Score = 34.7 bits (76), Expect = 0.35
Identities = 33/121 (27%), Positives = 49/121 (40%), Gaps = 9/121 (7%)
Frame = +2
Query: 152 STDEEEIDKNLATTDLDELVMNAANAE---------NPEAQLAAVQQCRKLLSCDKNPPI 304
ST EI K+ T +L +LV+NA +L + + + +N +
Sbjct: 272 STLIREIAKH--TPELSQLVVNAGGVAAVIDCIGSCKGNTRLPGIMMLGYVAAHSENLAM 329
Query: 305 DELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLM 484
+I+ G+ P L CLS ++ AWAL I T V +PV L L M
Sbjct: 330 AVIISKGV-PQLSVCLSEEPEDHIKAAAAWALGQIGRHTPEHARAVAVTNTLPVLLSLYM 388
Query: 485 S 487
S
Sbjct: 389 S 389
>AL513128-4|CAH72210.1| 509|Homo sapiens sperm associated antigen 6
protein.
Length = 509
Score = 50.4 bits (115), Expect = 7e-06
Identities = 33/99 (33%), Positives = 47/99 (47%)
Frame = +2
Query: 311 LIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSP 490
++ G L LV CL D P ++ AWAL IA + + VV AGAVP+ + + P
Sbjct: 121 IVDCGALDTLVICLEDFD-PGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEP 179
Query: 491 HENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLI 607
+ A AL +I P L V++ G V L +I
Sbjct: 180 EIALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMI 218
Score = 45.6 bits (103), Expect = 2e-04
Identities = 29/100 (29%), Positives = 52/100 (52%)
Frame = +2
Query: 311 LIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSP 490
++ AG +P+LV C+ + AL+ A AL++IA + VV AGAV Q++++P
Sbjct: 163 VVDAGAVPLLVLCIQEPEI-ALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMILNP 221
Query: 491 HENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIK 610
+ Q + AL + L + V+E + +L+ +K
Sbjct: 222 DAKLKHQILSALSQVSKHSVDLAEMVVEAEIFPVVLTCLK 261
Score = 34.7 bits (76), Expect = 0.35
Identities = 33/121 (27%), Positives = 49/121 (40%), Gaps = 9/121 (7%)
Frame = +2
Query: 152 STDEEEIDKNLATTDLDELVMNAANAE---------NPEAQLAAVQQCRKLLSCDKNPPI 304
ST EI K+ T +L +LV+NA +L + + + +N +
Sbjct: 272 STLIREIAKH--TPELSQLVVNAGGVAAVIDCIGSCKGNTRLPGIMMLGYVAAHSENLAM 329
Query: 305 DELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLM 484
+I+ G+ P L CLS ++ AWAL I T V +PV L L M
Sbjct: 330 AVIISKGV-PQLSVCLSEEPEDHIKAAAAWALGQIGRHTPEHARAVAVTNTLPVLLSLYM 388
Query: 485 S 487
S
Sbjct: 389 S 389
>AL513128-3|CAH72209.1| 458|Homo sapiens sperm associated antigen 6
protein.
Length = 458
Score = 50.4 bits (115), Expect = 7e-06
Identities = 33/99 (33%), Positives = 47/99 (47%)
Frame = +2
Query: 311 LIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSP 490
++ G L LV CL D P ++ AWAL IA + + VV AGAVP+ + + P
Sbjct: 121 IVDCGALDTLVICLEDFD-PGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEP 179
Query: 491 HENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLI 607
+ A AL +I P L V++ G V L +I
Sbjct: 180 EIALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMI 218
Score = 45.6 bits (103), Expect = 2e-04
Identities = 29/100 (29%), Positives = 52/100 (52%)
Frame = +2
Query: 311 LIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSP 490
++ AG +P+LV C+ + AL+ A AL++IA + VV AGAV Q++++P
Sbjct: 163 VVDAGAVPLLVLCIQEPEI-ALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMILNP 221
Query: 491 HENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIK 610
+ Q + AL + L + V+E + +L+ +K
Sbjct: 222 DAKLKHQILSALSQVSKHSVDLAEMVVEAEIFPVVLTCLK 261
Score = 34.7 bits (76), Expect = 0.35
Identities = 33/121 (27%), Positives = 49/121 (40%), Gaps = 9/121 (7%)
Frame = +2
Query: 152 STDEEEIDKNLATTDLDELVMNAANAE---------NPEAQLAAVQQCRKLLSCDKNPPI 304
ST EI K+ T +L +LV+NA +L + + + +N +
Sbjct: 272 STLIREIAKH--TPELSQLVVNAGGVAAVIDCIGSCKGNTRLPGIMMLGYVAAHSENLAM 329
Query: 305 DELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLM 484
+I+ G+ P L CLS ++ AWAL I T V +PV L L M
Sbjct: 330 AVIISKGV-PQLSVCLSEEPEDHIKAAAAWALGQIGRHTPEHARAVAVTNTLPVLLSLYM 388
Query: 485 S 487
S
Sbjct: 389 S 389
>AL158211-15|CAI15963.1| 509|Homo sapiens sperm associated antigen
6 protein.
Length = 509
Score = 50.4 bits (115), Expect = 7e-06
Identities = 33/99 (33%), Positives = 47/99 (47%)
Frame = +2
Query: 311 LIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSP 490
++ G L LV CL D P ++ AWAL IA + + VV AGAVP+ + + P
Sbjct: 121 IVDCGALDTLVICLEDFD-PGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEP 179
Query: 491 HENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLI 607
+ A AL +I P L V++ G V L +I
Sbjct: 180 EIALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMI 218
Score = 45.6 bits (103), Expect = 2e-04
Identities = 29/100 (29%), Positives = 52/100 (52%)
Frame = +2
Query: 311 LIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSP 490
++ AG +P+LV C+ + AL+ A AL++IA + VV AGAV Q++++P
Sbjct: 163 VVDAGAVPLLVLCIQEPEI-ALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMILNP 221
Query: 491 HENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIK 610
+ Q + AL + L + V+E + +L+ +K
Sbjct: 222 DAKLKHQILSALSQVSKHSVDLAEMVVEAEIFPVVLTCLK 261
Score = 34.7 bits (76), Expect = 0.35
Identities = 33/121 (27%), Positives = 49/121 (40%), Gaps = 9/121 (7%)
Frame = +2
Query: 152 STDEEEIDKNLATTDLDELVMNAANAE---------NPEAQLAAVQQCRKLLSCDKNPPI 304
ST EI K+ T +L +LV+NA +L + + + +N +
Sbjct: 272 STLIREIAKH--TPELSQLVVNAGGVAAVIDCIGSCKGNTRLPGIMMLGYVAAHSENLAM 329
Query: 305 DELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLM 484
+I+ G+ P L CLS ++ AWAL I T V +PV L L M
Sbjct: 330 AVIISKGV-PQLSVCLSEEPEDHIKAAAAWALGQIGRHTPEHARAVAVTNTLPVLLSLYM 388
Query: 485 S 487
S
Sbjct: 389 S 389
>AL158211-14|CAI15962.1| 458|Homo sapiens sperm associated antigen
6 protein.
Length = 458
Score = 50.4 bits (115), Expect = 7e-06
Identities = 33/99 (33%), Positives = 47/99 (47%)
Frame = +2
Query: 311 LIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSP 490
++ G L LV CL D P ++ AWAL IA + + VV AGAVP+ + + P
Sbjct: 121 IVDCGALDTLVICLEDFD-PGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEP 179
Query: 491 HENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLI 607
+ A AL +I P L V++ G V L +I
Sbjct: 180 EIALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMI 218
Score = 45.6 bits (103), Expect = 2e-04
Identities = 29/100 (29%), Positives = 52/100 (52%)
Frame = +2
Query: 311 LIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSP 490
++ AG +P+LV C+ + AL+ A AL++IA + VV AGAV Q++++P
Sbjct: 163 VVDAGAVPLLVLCIQEPEI-ALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMILNP 221
Query: 491 HENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIK 610
+ Q + AL + L + V+E + +L+ +K
Sbjct: 222 DAKLKHQILSALSQVSKHSVDLAEMVVEAEIFPVVLTCLK 261
Score = 34.7 bits (76), Expect = 0.35
Identities = 33/121 (27%), Positives = 49/121 (40%), Gaps = 9/121 (7%)
Frame = +2
Query: 152 STDEEEIDKNLATTDLDELVMNAANAE---------NPEAQLAAVQQCRKLLSCDKNPPI 304
ST EI K+ T +L +LV+NA +L + + + +N +
Sbjct: 272 STLIREIAKH--TPELSQLVVNAGGVAAVIDCIGSCKGNTRLPGIMMLGYVAAHSENLAM 329
Query: 305 DELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLM 484
+I+ G+ P L CLS ++ AWAL I T V +PV L L M
Sbjct: 330 AVIISKGV-PQLSVCLSEEPEDHIKAAAAWALGQIGRHTPEHARAVAVTNTLPVLLSLYM 388
Query: 485 S 487
S
Sbjct: 389 S 389
>AF079363-1|AAC32590.1| 509|Homo sapiens sperm flagellar protein
Repro-SA-1 protein.
Length = 509
Score = 50.4 bits (115), Expect = 7e-06
Identities = 33/99 (33%), Positives = 47/99 (47%)
Frame = +2
Query: 311 LIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSP 490
++ G L LV CL D P ++ AWAL IA + + VV AGAVP+ + + P
Sbjct: 121 IVDCGALDTLVICLEDFD-PGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEP 179
Query: 491 HENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLI 607
+ A AL +I P L V++ G V L +I
Sbjct: 180 EIALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMI 218
Score = 45.6 bits (103), Expect = 2e-04
Identities = 29/100 (29%), Positives = 52/100 (52%)
Frame = +2
Query: 311 LIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSP 490
++ AG +P+LV C+ + AL+ A AL++IA + VV AGAV Q++++P
Sbjct: 163 VVDAGAVPLLVLCIQEPEI-ALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMILNP 221
Query: 491 HENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIK 610
+ Q + AL + L + V+E + +L+ +K
Sbjct: 222 DAKLKHQILSALSQVSKHSVDLAEMVVEAEIFPVVLTCLK 261
Score = 34.7 bits (76), Expect = 0.35
Identities = 33/121 (27%), Positives = 49/121 (40%), Gaps = 9/121 (7%)
Frame = +2
Query: 152 STDEEEIDKNLATTDLDELVMNAANAE---------NPEAQLAAVQQCRKLLSCDKNPPI 304
ST EI K+ T +L +LV+NA +L + + + +N +
Sbjct: 272 STLIREIAKH--TPELSQLVVNAGGVAAVIDCIGSCKGNTRLPGIMMLGYVAAHSENLAM 329
Query: 305 DELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLM 484
+I+ G+ P L CLS ++ AWAL I T V +PV L L M
Sbjct: 330 AVIISKGV-PQLSVCLSEEPEDHIKAAAAWALGQIGRHTPEHARAVAVTNTLPVLLSLYM 388
Query: 485 S 487
S
Sbjct: 389 S 389
>AY217348-1|AAO45101.1| 725|Homo sapiens FLJ00019-like protein
protein.
Length = 725
Score = 41.5 bits (93), Expect = 0.003
Identities = 31/95 (32%), Positives = 48/95 (50%)
Frame = +2
Query: 323 GILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENV 502
GILP LV L ++Q TA AL N+A + + AGAVP+ ++ L + ++
Sbjct: 154 GILP-LVTILQCMKTDSIQNRTARALGNLAMEPES-CGDIHCAGAVPLLVESLTACQDSQ 211
Query: 503 CDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLI 607
C Q+V + D P R + + G V+PL L+
Sbjct: 212 CLQSVVRALRNLADSPQHRLALAQQGAVRPLAELL 246
>AK024430-1|BAB15720.1| 732|Homo sapiens FLJ00019 protein protein.
Length = 732
Score = 41.1 bits (92), Expect = 0.004
Identities = 31/95 (32%), Positives = 48/95 (50%)
Frame = +2
Query: 323 GILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENV 502
GILP LV L ++Q TA AL N+A + + AGAVP+ ++ L + ++
Sbjct: 161 GILP-LVTILQCMKTDSVQNRTARALGNLAMEPES-CGDIHCAGAVPLLVESLTACQDSQ 218
Query: 503 CDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLI 607
C Q+V + D P R + + G V+PL L+
Sbjct: 219 CLQSVVRALRNLADSPQHRLALAQQGAVRPLAELL 253
>X63465-1|CAA45067.1| 558|Homo sapiens smg GDS protein.
Length = 558
Score = 37.1 bits (82), Expect = 0.067
Identities = 40/144 (27%), Positives = 62/144 (43%), Gaps = 1/144 (0%)
Frame = +2
Query: 179 NLATTDLDELVMNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELI-AAGILPILVQCLS 355
NL+ T L +L + A + E L C N E I A+GIL + L+
Sbjct: 3 NLSDT-LKKLKITAV--DKTEDSLEGCLDCLLQALAQNNTETSEKIQASGILQLFASLLT 59
Query: 356 RADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNI 535
+ + + A + +A + V AG + +QLL S + V Q ALGNI
Sbjct: 60 --PQSSCKAKVANIIAEVAKNEFMRI-PCVDAGLISPLVQLLNSKDQEVLLQTGRALGNI 116
Query: 536 IGDGPVLRDFVIELGVVKPLLSLI 607
D L+ +I +GV+ L+ L+
Sbjct: 117 CYDSHSLQAQLINMGVIPTLVKLL 140
>BC099845-1|AAH99845.1| 559|Homo sapiens RAP1GDS1 protein protein.
Length = 559
Score = 37.1 bits (82), Expect = 0.067
Identities = 40/144 (27%), Positives = 62/144 (43%), Gaps = 1/144 (0%)
Frame = +2
Query: 179 NLATTDLDELVMNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELI-AAGILPILVQCLS 355
NL+ T L +L + A + E L C N E I A+GIL + L+
Sbjct: 4 NLSDT-LKKLKITAV--DKTEDSLEGCLDCLLQALAQNNTETSEKIQASGILQLFASLLT 60
Query: 356 RADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNI 535
+ + + A + +A + V AG + +QLL S + V Q ALGNI
Sbjct: 61 --PQSSCKAKVANIIAEVAKNEFMRI-PCVDAGLISPLVQLLNSKDQEVLLQTGRALGNI 117
Query: 536 IGDGPVLRDFVIELGVVKPLLSLI 607
D L+ +I +GV+ L+ L+
Sbjct: 118 CYDSHSLQAQLINMGVIPTLVKLL 141
>BC099708-1|AAH99708.1| 558|Homo sapiens RAP1GDS1 protein protein.
Length = 558
Score = 37.1 bits (82), Expect = 0.067
Identities = 40/144 (27%), Positives = 62/144 (43%), Gaps = 1/144 (0%)
Frame = +2
Query: 179 NLATTDLDELVMNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELI-AAGILPILVQCLS 355
NL+ T L +L + A + E L C N E I A+GIL + L+
Sbjct: 3 NLSDT-LKKLKITAV--DKTEDSLEGCLDCLLQALAQNNTETSEKIQASGILQLFASLLT 59
Query: 356 RADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNI 535
+ + + A + +A + V AG + +QLL S + V Q ALGNI
Sbjct: 60 --PQSSCKAKVANIIAEVAKNEFMRI-PCVDAGLISPLVQLLNSKDQEVLLQTGRALGNI 116
Query: 536 IGDGPVLRDFVIELGVVKPLLSLI 607
D L+ +I +GV+ L+ L+
Sbjct: 117 CYDSHSLQAQLINMGVIPTLVKLL 140
>BC098334-1|AAH98334.1| 558|Homo sapiens RAP1GDS1 protein protein.
Length = 558
Score = 37.1 bits (82), Expect = 0.067
Identities = 40/144 (27%), Positives = 62/144 (43%), Gaps = 1/144 (0%)
Frame = +2
Query: 179 NLATTDLDELVMNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELI-AAGILPILVQCLS 355
NL+ T L +L + A + E L C N E I A+GIL + L+
Sbjct: 3 NLSDT-LKKLKITAV--DKTEDSLEGCLDCLLQALAQNNTETSEKIQASGILQLFASLLT 59
Query: 356 RADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNI 535
+ + + A + +A + V AG + +QLL S + V Q ALGNI
Sbjct: 60 --PQSSCKAKVANIIAEVAKNEFMRI-PCVDAGLISPLVQLLNSKDQEVLLQTGRALGNI 116
Query: 536 IGDGPVLRDFVIELGVVKPLLSLI 607
D L+ +I +GV+ L+ L+
Sbjct: 117 CYDSHSLQAQLINMGVIPTLVKLL 140
>BC041699-1|AAH41699.1| 659|Homo sapiens armadillo repeat
containing 8 protein.
Length = 659
Score = 35.9 bits (79), Expect = 0.15
Identities = 33/171 (19%), Positives = 76/171 (44%), Gaps = 3/171 (1%)
Frame = +2
Query: 224 NAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAWALT 403
NA + +A+ C LL + +P + ++ +G + +L L++++NPAL+ WAL
Sbjct: 423 NAPDEILVVASSMLCNLLL--EFSPSKEPILESGAVELLCG-LTQSENPALRVNGIWALM 479
Query: 404 NIASGTSAQTN-KVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELG 580
N+A + ++ + + +LL NV + + L N++ P + + G
Sbjct: 480 NMAFQAEQKIKADILRSLSTEQLFRLLSDSDLNVLMKTLGLLRNLLSTRPHIDKIMSTHG 539
Query: 581 --VVKPLLSLIKSDIPIPFLRNVTWVIVNLCRSKDPPPPLKTIQEILPGLK 727
+++ + +++ + I ++ N+ + T +IL +K
Sbjct: 540 KQIMQAVTLILEGEHNIEVKEQTLCILANIADGTTAKDLIMTNDDILQKIK 590
>BC032661-1|AAH32661.1| 659|Homo sapiens armadillo repeat
containing 8 protein.
Length = 659
Score = 35.9 bits (79), Expect = 0.15
Identities = 33/171 (19%), Positives = 76/171 (44%), Gaps = 3/171 (1%)
Frame = +2
Query: 224 NAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAWALT 403
NA + +A+ C LL + +P + ++ +G + +L L++++NPAL+ WAL
Sbjct: 423 NAPDEILVVASSMLCNLLL--EFSPSKEPILESGAVELLCG-LTQSENPALRVNGIWALM 479
Query: 404 NIASGTSAQTN-KVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELG 580
N+A + ++ + + +LL NV + + L N++ P + + G
Sbjct: 480 NMAFQAEQKIKADILRSLSTEQLFRLLSDSDLNVLMKTLGLLRNLLSTRPHIDKIMSTHG 539
Query: 581 --VVKPLLSLIKSDIPIPFLRNVTWVIVNLCRSKDPPPPLKTIQEILPGLK 727
+++ + +++ + I ++ N+ + T +IL +K
Sbjct: 540 KQIMQAVTLILEGEHNIEVKEQTLCILANIADGTTAKDLIMTNDDILQKIK 590
>BC014945-1|AAH14945.1| 771|Homo sapiens ARMC5 protein protein.
Length = 771
Score = 35.9 bits (79), Expect = 0.15
Identities = 24/79 (30%), Positives = 41/79 (51%)
Frame = +2
Query: 371 ALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGP 550
++Q TA AL N+A + + AGAVP+ ++ L + ++ C Q+V + D P
Sbjct: 5 SIQNRTARALGNLAMEPES-CGDIHCAGAVPLLVESLTACQDSQCLQSVVRALRNLADSP 63
Query: 551 VLRDFVIELGVVKPLLSLI 607
R + + G V+PL L+
Sbjct: 64 QHRLALAQQGAVRPLAELL 82
>AL513128-1|CAH72207.1| 246|Homo sapiens sperm associated antigen 6
protein.
Length = 246
Score = 35.9 bits (79), Expect = 0.15
Identities = 21/51 (41%), Positives = 27/51 (52%)
Frame = +2
Query: 311 LIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVP 463
++ G L LV CL D P ++ AWAL IA + + VV AGAVP
Sbjct: 197 IVDCGALDTLVICLEDFD-PGVKEAAAWALRYIARHNAELSQAVVDAGAVP 246
>AL158211-12|CAI15960.1| 246|Homo sapiens sperm associated antigen
6 protein.
Length = 246
Score = 35.9 bits (79), Expect = 0.15
Identities = 21/51 (41%), Positives = 27/51 (52%)
Frame = +2
Query: 311 LIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVP 463
++ G L LV CL D P ++ AWAL IA + + VV AGAVP
Sbjct: 197 IVDCGALDTLVICLEDFD-PGVKEAAAWALRYIARHNAELSQAVVDAGAVP 246
>AL096748-1|CAB46423.1| 242|Homo sapiens hypothetical protein
protein.
Length = 242
Score = 35.9 bits (79), Expect = 0.15
Identities = 33/171 (19%), Positives = 76/171 (44%), Gaps = 3/171 (1%)
Frame = +2
Query: 224 NAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAWALT 403
NA + +A+ C LL + +P + ++ +G + +L L++++NPAL+ WAL
Sbjct: 6 NAPDEILVVASSMLCNLLL--EFSPSKEPILESGAVELLCG-LTQSENPALRVNGIWALM 62
Query: 404 NIASGTSAQTN-KVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELG 580
N+A + ++ + + +LL NV + + L N++ P + + G
Sbjct: 63 NMAFQAEQKIKADILRSLSTEQLFRLLSDSDLNVLMKTLGLLRNLLSTRPHIDKIMSTHG 122
Query: 581 --VVKPLLSLIKSDIPIPFLRNVTWVIVNLCRSKDPPPPLKTIQEILPGLK 727
+++ + +++ + I ++ N+ + T +IL +K
Sbjct: 123 KQIMQAVTLILEGEHNIEVKEQTLCILANIADGTTAKDLIMTNDDILQKIK 173
>AK023125-1|BAB14418.1| 502|Homo sapiens protein ( Homo sapiens
cDNA FLJ13063 fis, clone NT2RP3001678. ).
Length = 502
Score = 35.9 bits (79), Expect = 0.15
Identities = 24/79 (30%), Positives = 41/79 (51%)
Frame = +2
Query: 371 ALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGP 550
++Q TA AL N+A + + AGAVP+ ++ L + ++ C Q+V + D P
Sbjct: 5 SIQNRTARALGNLAMEPES-CGDIHCAGAVPLLVESLTACQDSQCLQSVVRALRNLADSP 63
Query: 551 VLRDFVIELGVVKPLLSLI 607
R + + G V+PL L+
Sbjct: 64 QHRLALAQQGAVRPLAELL 82
>AK001882-1|BAA91959.1| 431|Homo sapiens protein ( Homo sapiens
cDNA FLJ11020 fis, clone PLACE1003625, weakly similar to
ARMADILLO SEGMENT POLARITY PROTEIN. ).
Length = 431
Score = 33.9 bits (74), Expect = 0.62
Identities = 32/171 (18%), Positives = 76/171 (44%), Gaps = 3/171 (1%)
Frame = +2
Query: 224 NAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAWALT 403
NA + +A+ C LL + +P + ++ +G + +L L++++NPAL+ WAL
Sbjct: 195 NAPDEILVVASSMLCNLLL--EFSPSKEPILESGAVELLCG-LTQSENPALRVNGIWALM 251
Query: 404 NIASGTSAQTN-KVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELG 580
N+A + ++ + + +LL NV + + L +++ P + + G
Sbjct: 252 NMAFQAEQKIKADILRSLSTEQLFRLLSDSDLNVLMKTLGLLRSLLSTRPHIDKIMSTHG 311
Query: 581 --VVKPLLSLIKSDIPIPFLRNVTWVIVNLCRSKDPPPPLKTIQEILPGLK 727
+++ + +++ + I ++ N+ + T +IL +K
Sbjct: 312 KQIMQAVTLILEGEHNIEVKEQTLCILANIADGTTAKDLIMTNDDILQKIK 362
>BC011728-1|AAH11728.1| 198|Homo sapiens armadillo repeat
containing 7 protein.
Length = 198
Score = 33.5 bits (73), Expect = 0.82
Identities = 26/112 (23%), Positives = 50/112 (44%), Gaps = 1/112 (0%)
Frame = +2
Query: 326 ILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVC 505
+L + + LS + ++F L N+ A ++HAG VP+ + L SP+E
Sbjct: 58 VLDLFLDSLSEENETLVEFAIG-GLCNLCPDR-ANKEHILHAGGVPLIINCLSSPNEETV 115
Query: 506 DQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPF-LRNVTWVIV 658
A+ L ++ P R F+ EL + +++ + LRN+ + +
Sbjct: 116 LSAITTLMHL---SPPGRSFLPELTATPVVQCMLRFSLSASARLRNLAQIFL 164
>AL513128-2|CAH72208.1| 191|Homo sapiens sperm associated antigen 6
protein.
Length = 191
Score = 33.5 bits (73), Expect = 0.82
Identities = 22/72 (30%), Positives = 29/72 (40%), Gaps = 1/72 (1%)
Frame = +2
Query: 275 LLSCDKNPP-IDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHA 451
++ CD P + L +P L CLS ++ AWAL I T V
Sbjct: 79 VVKCDILPQLVYSLAEQNGVPQLSVCLSEEPEDHIKAAAAWALGQIGRHTPEHARAVAVT 138
Query: 452 GAVPVFLQLLMS 487
+PV L L MS
Sbjct: 139 NTLPVLLSLYMS 150
>AL158211-13|CAI15961.1| 191|Homo sapiens sperm associated antigen
6 protein.
Length = 191
Score = 33.5 bits (73), Expect = 0.82
Identities = 22/72 (30%), Positives = 29/72 (40%), Gaps = 1/72 (1%)
Frame = +2
Query: 275 LLSCDKNPP-IDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHA 451
++ CD P + L +P L CLS ++ AWAL I T V
Sbjct: 79 VVKCDILPQLVYSLAEQNGVPQLSVCLSEEPEDHIKAAAAWALGQIGRHTPEHARAVAVT 138
Query: 452 GAVPVFLQLLMS 487
+PV L L MS
Sbjct: 139 NTLPVLLSLYMS 150
>AK025813-1|BAB15242.1| 198|Homo sapiens protein ( Homo sapiens
cDNA: FLJ22160 fis, clone HRC00266. ).
Length = 198
Score = 33.5 bits (73), Expect = 0.82
Identities = 26/112 (23%), Positives = 50/112 (44%), Gaps = 1/112 (0%)
Frame = +2
Query: 326 ILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVC 505
+L + + LS + ++F L N+ A ++HAG VP+ + L SP+E
Sbjct: 58 VLDLFLDSLSEENETLVEFAIG-GLCNLCPDR-ANKEHILHAGGVPLIINCLSSPNEETV 115
Query: 506 DQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKSDIPIPF-LRNVTWVIV 658
A+ L ++ P R F+ EL + +++ + LRN+ + +
Sbjct: 116 LSAITTLMHL---SPPGRSFLPELTATPVVQCMLRFSLSASARLRNLAQIFL 164
>BC039312-1|AAH39312.1| 872|Homo sapiens armadillo repeat
containing 3 protein.
Length = 872
Score = 33.1 bits (72), Expect = 1.1
Identities = 17/52 (32%), Positives = 27/52 (51%)
Frame = +2
Query: 458 VPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKS 613
+P +QLL S +E V + A AL N+ P + E + PL++L+ S
Sbjct: 358 IPQLIQLLKSDNEEVREAAALALANLTTCNPANANAAAEADGIDPLINLLSS 409
>AY436643-1|AAR99738.1| 688|Homo sapiens beta-catenin-like protein
protein.
Length = 688
Score = 33.1 bits (72), Expect = 1.1
Identities = 17/52 (32%), Positives = 27/52 (51%)
Frame = +2
Query: 458 VPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKS 613
+P +QLL S +E V + A AL N+ P + E + PL++L+ S
Sbjct: 358 IPQLIQLLKSDNEEVREAAALALANLTTCNPANANAAAEADGIDPLINLLSS 409
>AL139815-2|CAH72189.1| 875|Homo sapiens novel protein protein.
Length = 875
Score = 33.1 bits (72), Expect = 1.1
Identities = 17/52 (32%), Positives = 27/52 (51%)
Frame = +2
Query: 458 VPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKS 613
+P +QLL S +E V + A AL N+ P + E + PL++L+ S
Sbjct: 358 IPQLIQLLKSDNEEVREAAALALANLTTCNPANANAAAEADGIDPLINLLSS 409
>AL139815-1|CAH72188.1| 546|Homo sapiens novel protein protein.
Length = 546
Score = 33.1 bits (72), Expect = 1.1
Identities = 17/52 (32%), Positives = 27/52 (51%)
Frame = +2
Query: 458 VPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKS 613
+P +QLL S +E V + A AL N+ P + E + PL++L+ S
Sbjct: 294 IPQLIQLLKSDNEEVREAAALALANLTTCNPANANAAAEADGIDPLINLLSS 345
>AK057389-1|BAB71463.1| 669|Homo sapiens protein ( Homo sapiens
cDNA FLJ32827 fis, clone TESTI2003109, weakly similar to
VACUOLAR PROTEIN 8. ).
Length = 669
Score = 33.1 bits (72), Expect = 1.1
Identities = 17/52 (32%), Positives = 27/52 (51%)
Frame = +2
Query: 458 VPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLIKS 613
+P +QLL S +E V + A AL N+ P + E + PL++L+ S
Sbjct: 358 IPQLIQLLKSDNEEVREAAALALANLTTCNPANANAAAEADGIDPLINLLSS 409
>D50550-1|BAA19516.1| 1032|Homo sapiens LLGL protein.
Length = 1032
Score = 32.7 bits (71), Expect = 1.4
Identities = 21/62 (33%), Positives = 32/62 (51%), Gaps = 1/62 (1%)
Frame = +2
Query: 320 AGILP-ILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHE 496
AG LP +LVQCL A A+ T W+L +A GTS + PV + + P++
Sbjct: 585 AGFLPRVLVQCLPPAAVTAVTLHTEWSL--VAFGTSHGFGLFDYQRKSPVLARCTLHPND 642
Query: 497 NV 502
++
Sbjct: 643 SL 644
>Z83131-1|CAI42019.1| 632|Homo sapiens armadillo repeat containing,
X-linked 2 protein.
Length = 632
Score = 31.9 bits (69), Expect = 2.5
Identities = 20/92 (21%), Positives = 45/92 (48%), Gaps = 3/92 (3%)
Frame = +2
Query: 269 RKLLSCDKNP---PIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNK 439
R+ ++ K P IDE++ L ++ L ++D+P +Q L+N A+ S
Sbjct: 365 RRPVAMQKRPFPYEIDEILGVRDLRKVLALLQKSDDPFIQQVALLTLSNNAN-YSCNQET 423
Query: 440 VVHAGAVPVFLQLLMSPHENVCDQAVWALGNI 535
+ G +P+ ++ ++ ++A+ A+ N+
Sbjct: 424 IRKLGGLPIIANMINKTDPHIKEKALMAMNNL 455
>BC015926-1|AAH15926.1| 632|Homo sapiens ARMCX2 protein protein.
Length = 632
Score = 31.9 bits (69), Expect = 2.5
Identities = 20/92 (21%), Positives = 45/92 (48%), Gaps = 3/92 (3%)
Frame = +2
Query: 269 RKLLSCDKNP---PIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNK 439
R+ ++ K P IDE++ L ++ L ++D+P +Q L+N A+ S
Sbjct: 365 RRPVAMQKRPFPYEIDEILGVRDLRKVLALLQKSDDPFIQQVALLTLSNNAN-YSCNQET 423
Query: 440 VVHAGAVPVFLQLLMSPHENVCDQAVWALGNI 535
+ G +P+ ++ ++ ++A+ A+ N+
Sbjct: 424 IRKLGGLPIIANMINKTDPHIKEKALMAMNNL 455
>BC012541-1|AAH12541.1| 632|Homo sapiens armadillo repeat
containing, X-linked 2 protein.
Length = 632
Score = 31.9 bits (69), Expect = 2.5
Identities = 20/92 (21%), Positives = 45/92 (48%), Gaps = 3/92 (3%)
Frame = +2
Query: 269 RKLLSCDKNP---PIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNK 439
R+ ++ K P IDE++ L ++ L ++D+P +Q L+N A+ S
Sbjct: 365 RRPVAMQKRPFPYEIDEILGVRDLRKVLALLQKSDDPFIQQVALLTLSNNAN-YSCNQET 423
Query: 440 VVHAGAVPVFLQLLMSPHENVCDQAVWALGNI 535
+ G +P+ ++ ++ ++A+ A+ N+
Sbjct: 424 IRKLGGLPIIANMINKTDPHIKEKALMAMNNL 455
>BC009618-1|AAH09618.1| 253|Homo sapiens TMCO6 protein protein.
Length = 253
Score = 31.9 bits (69), Expect = 2.5
Identities = 25/112 (22%), Positives = 49/112 (43%)
Frame = +2
Query: 386 TAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLRDF 565
T A+ + + +VV A+ + LQ ++ + +W L N+ + P
Sbjct: 80 TEAAVETVGGQMQLRDERVV--AALFILLQFFFQKQPSLLPEGLWLLNNLTANSPSFCTS 137
Query: 566 VIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNLCRSKDPPPPLKTIQEILPG 721
++ L +++PLL L +P+ + +V V+ LC + P Q + PG
Sbjct: 138 LLSLDLIEPLLQL----LPVSNVVSV-MVLTVLCNVAEKGPAY--CQRLWPG 182
>BC001910-1|AAH01910.1| 253|Homo sapiens TMCO6 protein protein.
Length = 253
Score = 31.9 bits (69), Expect = 2.5
Identities = 25/112 (22%), Positives = 49/112 (43%)
Frame = +2
Query: 386 TAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLRDF 565
T A+ + + +VV A+ + LQ ++ + +W L N+ + P
Sbjct: 80 TEAAVETVGGQMQLRDERVV--AALFILLQFFFQKQPSLLPEGLWLLNNLTANSPSFCTS 137
Query: 566 VIELGVVKPLLSLIKSDIPIPFLRNVTWVIVNLCRSKDPPPPLKTIQEILPG 721
++ L +++PLL L +P+ + +V V+ LC + P Q + PG
Sbjct: 138 LLSLDLIEPLLQL----LPVSNVVSV-MVLTVLCNVAEKGPAY--CQRLWPG 182
>AB011084-1|BAA25438.2| 710|Homo sapiens KIAA0512 protein protein.
Length = 710
Score = 31.9 bits (69), Expect = 2.5
Identities = 20/92 (21%), Positives = 45/92 (48%), Gaps = 3/92 (3%)
Frame = +2
Query: 269 RKLLSCDKNP---PIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNK 439
R+ ++ K P IDE++ L ++ L ++D+P +Q L+N A+ S
Sbjct: 443 RRPVAMQKRPFPYEIDEILGVRDLRKVLALLQKSDDPFIQQVALLTLSNNAN-YSCNQET 501
Query: 440 VVHAGAVPVFLQLLMSPHENVCDQAVWALGNI 535
+ G +P+ ++ ++ ++A+ A+ N+
Sbjct: 502 IRKLGGLPIIANMINKTDPHIKEKALMAMNNL 533
>BC132827-1|AAI32828.1| 949|Homo sapiens CCDC66 protein protein.
Length = 949
Score = 31.5 bits (68), Expect = 3.3
Identities = 23/82 (28%), Positives = 37/82 (45%)
Frame = +2
Query: 32 KNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYSTDEEEIDKNLATTDLDELV 211
K K ++E +R++ E ELR + E +QK+ I +EEI T +EL
Sbjct: 478 KRRKKQLEEEQRKKEEQEEELRLAQEREEMQKQYEEDILKQKQKEEI----MTLKTNELF 533
Query: 212 MNAANAENPEAQLAAVQQCRKL 277
A+ +L Q+ R+L
Sbjct: 534 QTMQRAQELAQRLKQEQRIREL 555
>BC047509-1|AAH47509.1| 831|Homo sapiens coiled-coil domain
containing 66 protein.
Length = 831
Score = 31.5 bits (68), Expect = 3.3
Identities = 23/82 (28%), Positives = 37/82 (45%)
Frame = +2
Query: 32 KNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYSTDEEEIDKNLATTDLDELV 211
K K ++E +R++ E ELR + E +QK+ I +EEI T +EL
Sbjct: 361 KRRKKQLEEEQRKKEEQEEELRLAQEREEMQKQYEEDILKQKQKEEI----MTLKTNELF 416
Query: 212 MNAANAENPEAQLAAVQQCRKL 277
A+ +L Q+ R+L
Sbjct: 417 QTMQRAQELAQRLKQEQRIREL 438
>AY376900-1|AAQ85126.1| 516|Homo sapiens GTP-GDP dissociation
stimulator 1 isoform A protein.
Length = 516
Score = 31.1 bits (67), Expect = 4.4
Identities = 32/131 (24%), Positives = 50/131 (38%), Gaps = 1/131 (0%)
Frame = +2
Query: 230 ENPEAQLAAVQQCRKLLSCDKNPPIDELI-AAGILPILVQCLSRADNPALQFETAWALTN 406
+ E L C N E I A+GIL + L+ + + + A +
Sbjct: 18 DKTEDSLEGCLDCLLQALAQNNTETSEKIQASGILQLFSSLLT--PQSSCKAKVANIIAE 75
Query: 407 IASGTSAQTNKVVHAGAVPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVV 586
+A + V AG + +QLL S + V Q ALGNI D ++ +
Sbjct: 76 VAKNEFMRI-PCVDAGLISPLVQLLNSKDQEVLLQTGRALGNICYDSQSSKEQFASTNIA 134
Query: 587 KPLLSLIKSDI 619
+ L+ L K I
Sbjct: 135 EELVKLFKKQI 145
>Z19054-1|CAA79497.1| 781|Homo sapiens beta catenin protein.
Length = 781
Score = 30.7 bits (66), Expect = 5.8
Identities = 21/62 (33%), Positives = 29/62 (46%), Gaps = 2/62 (3%)
Frame = +2
Query: 434 NKVVHAG--AVPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLI 607
N++V G +P+F+QLL SP EN+ A L + D E G PL L+
Sbjct: 586 NRIVIRGLNTIPLFVQLLYSPIENIQRVAAGVLCELAQDKEAAEAIEAE-GATAPLTELL 644
Query: 608 KS 613
S
Sbjct: 645 HS 646
>X87838-1|CAA61107.1| 781|Homo sapiens beta-catenin protein.
Length = 781
Score = 30.7 bits (66), Expect = 5.8
Identities = 21/62 (33%), Positives = 29/62 (46%), Gaps = 2/62 (3%)
Frame = +2
Query: 434 NKVVHAG--AVPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLI 607
N++V G +P+F+QLL SP EN+ A L + D E G PL L+
Sbjct: 586 NRIVIRGLNTIPLFVQLLYSPIENIQRVAAGVLCELAQDKEAAEAIEAE-GATAPLTELL 644
Query: 608 KS 613
S
Sbjct: 645 HS 646
>U72069-1|AAB58254.1| 890|Homo sapiens karyopherin beta2 protein.
Length = 890
Score = 30.7 bits (66), Expect = 5.8
Identities = 22/79 (27%), Positives = 39/79 (49%), Gaps = 1/79 (1%)
Frame = +2
Query: 302 IDELIA-AGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQL 478
I++L+A + IL ++ QC+ D ++++AL + Q K A +P+
Sbjct: 659 IEQLVARSNILTLMYQCMQ--DKMPEVRQSSFALLGDLTKACFQHVKPCIADFMPILGTN 716
Query: 479 LMSPHENVCDQAVWALGNI 535
L +VC+ A WA+G I
Sbjct: 717 LNPEFISVCNNATWAIGEI 735
>U70322-1|AAC50723.1| 890|Homo sapiens transportin protein.
Length = 890
Score = 30.7 bits (66), Expect = 5.8
Identities = 22/79 (27%), Positives = 39/79 (49%), Gaps = 1/79 (1%)
Frame = +2
Query: 302 IDELIA-AGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQL 478
I++L+A + IL ++ QC+ D ++++AL + Q K A +P+
Sbjct: 659 IEQLVARSNILTLMYQCMQ--DKMPEVRQSSFALLGDLTKACFQHVKPCIADFMPILGTN 716
Query: 479 LMSPHENVCDQAVWALGNI 535
L +VC+ A WA+G I
Sbjct: 717 LNPEFISVCNNATWAIGEI 735
>BC058926-1|AAH58926.1| 781|Homo sapiens catenin
(cadherin-associated protein), beta 1, 88kDa protein.
Length = 781
Score = 30.7 bits (66), Expect = 5.8
Identities = 21/62 (33%), Positives = 29/62 (46%), Gaps = 2/62 (3%)
Frame = +2
Query: 434 NKVVHAG--AVPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLI 607
N++V G +P+F+QLL SP EN+ A L + D E G PL L+
Sbjct: 586 NRIVIRGLNTIPLFVQLLYSPIENIQRVAAGVLCELAQDKEAAEAIEAE-GATAPLTELL 644
Query: 608 KS 613
S
Sbjct: 645 HS 646
>BC040340-1|AAH40340.1| 890|Homo sapiens transportin 1 protein.
Length = 890
Score = 30.7 bits (66), Expect = 5.8
Identities = 22/79 (27%), Positives = 39/79 (49%), Gaps = 1/79 (1%)
Frame = +2
Query: 302 IDELIA-AGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQL 478
I++L+A + IL ++ QC+ D ++++AL + Q K A +P+
Sbjct: 659 IEQLVARSNILTLMYQCMQ--DKMPEVRQSSFALLGDLTKACFQHVKPCIADFMPILGTN 716
Query: 479 LMSPHENVCDQAVWALGNI 535
L +VC+ A WA+G I
Sbjct: 717 LNPEFISVCNNATWAIGEI 735
>AY463360-1|AAR18817.1| 781|Homo sapiens catenin
(cadherin-associated protein), beta 1, 88kDa protein.
Length = 781
Score = 30.7 bits (66), Expect = 5.8
Identities = 21/62 (33%), Positives = 29/62 (46%), Gaps = 2/62 (3%)
Frame = +2
Query: 434 NKVVHAG--AVPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLI 607
N++V G +P+F+QLL SP EN+ A L + D E G PL L+
Sbjct: 586 NRIVIRGLNTIPLFVQLLYSPIENIQRVAAGVLCELAQDKEAAEAIEAE-GATAPLTELL 644
Query: 608 KS 613
S
Sbjct: 645 HS 646
>AB062292-1|BAB93475.1| 511|Homo sapiens catenin beta 1 protein.
Length = 511
Score = 30.7 bits (66), Expect = 5.8
Identities = 21/62 (33%), Positives = 29/62 (46%), Gaps = 2/62 (3%)
Frame = +2
Query: 434 NKVVHAG--AVPVFLQLLMSPHENVCDQAVWALGNIIGDGPVLRDFVIELGVVKPLLSLI 607
N++V G +P+F+QLL SP EN+ A L + D E G PL L+
Sbjct: 316 NRIVIRGLNTIPLFVQLLYSPIENIQRVAAGVLCELAQDKEAAEAIEAE-GATAPLTELL 374
Query: 608 KS 613
S
Sbjct: 375 HS 376
>BC117686-1|AAI17687.1| 1683|Homo sapiens SHPRH protein protein.
Length = 1683
Score = 30.3 bits (65), Expect = 7.6
Identities = 29/114 (25%), Positives = 53/114 (46%), Gaps = 4/114 (3%)
Frame = +2
Query: 65 RRRNEVTVELRKNKREETL----QKRRNVPISYSTDEEEIDKNLATTDLDELVMNAANAE 232
RR+ V + + KR++ + RRN PI S D+E+ T+ ++++ + E
Sbjct: 4 RRKRAPPVRVDEEKRQQLHWNMHEDRRNEPIIISDDDEQPCPGSDTSSAHYIILSDSLKE 63
Query: 233 NPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAW 394
E ++C K++S K PI++ GI L L+ +P F+ +W
Sbjct: 64 --EVAHRDKKRCSKVVSFSK--PIEKEETVGIFSPLSVKLNIVISP-YHFDNSW 112
>BC117685-1|AAI17686.1| 155|Homo sapiens SHPRH protein protein.
Length = 155
Score = 30.3 bits (65), Expect = 7.6
Identities = 29/114 (25%), Positives = 53/114 (46%), Gaps = 4/114 (3%)
Frame = +2
Query: 65 RRRNEVTVELRKNKREETL----QKRRNVPISYSTDEEEIDKNLATTDLDELVMNAANAE 232
RR+ V + + KR++ + RRN PI S D+E+ T+ ++++ + E
Sbjct: 4 RRKRAPPVRVDEEKRQQLHWNMHEDRRNEPIIISDDDEQPCPGSDTSSAHYIILSDSLKE 63
Query: 233 NPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAW 394
E ++C K++S K PI++ GI L L+ +P F+ +W
Sbjct: 64 --EVAHRDKKRCSKVVSFSK--PIEKEETVGIFSPLSVKLNIVISP-YHFDNSW 112
>BC113089-1|AAI13090.1| 155|Homo sapiens SHPRH protein protein.
Length = 155
Score = 30.3 bits (65), Expect = 7.6
Identities = 29/114 (25%), Positives = 53/114 (46%), Gaps = 4/114 (3%)
Frame = +2
Query: 65 RRRNEVTVELRKNKREETL----QKRRNVPISYSTDEEEIDKNLATTDLDELVMNAANAE 232
RR+ V + + KR++ + RRN PI S D+E+ T+ ++++ + E
Sbjct: 4 RRKRAPPVRVDEEKRQQLHWNMHEDRRNEPIIISDDDEQPCPGSDTSSAHYIILSDSLKE 63
Query: 233 NPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAW 394
E ++C K++S K PI++ GI L L+ +P F+ +W
Sbjct: 64 --EVAHRDKKRCSKVVSFSK--PIEKEETVGIFSPLSVKLNIVISP-YHFDNSW 112
>AY163808-1|AAO06907.1| 1659|Homo sapiens helicase-like protein
protein.
Length = 1659
Score = 30.3 bits (65), Expect = 7.6
Identities = 29/114 (25%), Positives = 53/114 (46%), Gaps = 4/114 (3%)
Frame = +2
Query: 65 RRRNEVTVELRKNKREETL----QKRRNVPISYSTDEEEIDKNLATTDLDELVMNAANAE 232
RR+ V + + KR++ + RRN PI S D+E+ T+ ++++ + E
Sbjct: 4 RRKRAPPVRVDEEKRQQLHWNMHEDRRNEPIIISDDDEQPCPGSDTSSAHYIILSDSLKE 63
Query: 233 NPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAW 394
E ++C K++S K PI++ GI L L+ +P F+ +W
Sbjct: 64 --EVAHRDKKRCSKVVSFSK--PIEKEETVGIFSPLSVKLNIVISP-YHFDNSW 112
>AY161136-1|AAO26201.1| 1683|Homo sapiens SNF2 histone linker PHD
RING helicase protein.
Length = 1683
Score = 30.3 bits (65), Expect = 7.6
Identities = 29/114 (25%), Positives = 53/114 (46%), Gaps = 4/114 (3%)
Frame = +2
Query: 65 RRRNEVTVELRKNKREETL----QKRRNVPISYSTDEEEIDKNLATTDLDELVMNAANAE 232
RR+ V + + KR++ + RRN PI S D+E+ T+ ++++ + E
Sbjct: 4 RRKRAPPVRVDEEKRQQLHWNMHEDRRNEPIIISDDDEQPCPGSDTSSAHYIILSDSLKE 63
Query: 233 NPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAW 394
E ++C K++S K PI++ GI L L+ +P F+ +W
Sbjct: 64 --EVAHRDKKRCSKVVSFSK--PIEKEETVGIFSPLSVKLNIVISP-YHFDNSW 112
>AL451145-1|CAH70765.1| 1683|Homo sapiens SNF2 histone linker PHD
RING helicase protein.
Length = 1683
Score = 30.3 bits (65), Expect = 7.6
Identities = 29/114 (25%), Positives = 53/114 (46%), Gaps = 4/114 (3%)
Frame = +2
Query: 65 RRRNEVTVELRKNKREETL----QKRRNVPISYSTDEEEIDKNLATTDLDELVMNAANAE 232
RR+ V + + KR++ + RRN PI S D+E+ T+ ++++ + E
Sbjct: 4 RRKRAPPVRVDEEKRQQLHWNMHEDRRNEPIIISDDDEQPCPGSDTSSAHYIILSDSLKE 63
Query: 233 NPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAW 394
E ++C K++S K PI++ GI L L+ +P F+ +W
Sbjct: 64 --EVAHRDKKRCSKVVSFSK--PIEKEETVGIFSPLSVKLNIVISP-YHFDNSW 112
>AL356599-2|CAI41120.1| 1683|Homo sapiens SNF2 histone linker PHD
RING helicase protein.
Length = 1683
Score = 30.3 bits (65), Expect = 7.6
Identities = 29/114 (25%), Positives = 53/114 (46%), Gaps = 4/114 (3%)
Frame = +2
Query: 65 RRRNEVTVELRKNKREETL----QKRRNVPISYSTDEEEIDKNLATTDLDELVMNAANAE 232
RR+ V + + KR++ + RRN PI S D+E+ T+ ++++ + E
Sbjct: 4 RRKRAPPVRVDEEKRQQLHWNMHEDRRNEPIIISDDDEQPCPGSDTSSAHYIILSDSLKE 63
Query: 233 NPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAW 394
E ++C K++S K PI++ GI L L+ +P F+ +W
Sbjct: 64 --EVAHRDKKRCSKVVSFSK--PIEKEETVGIFSPLSVKLNIVISP-YHFDNSW 112
>AK075318-1|BAC11544.1| 584|Homo sapiens protein ( Homo sapiens
cDNA FLJ90837 fis, clone Y79AA1002121, weakly similar to
HISTONE H1. ).
Length = 584
Score = 30.3 bits (65), Expect = 7.6
Identities = 29/114 (25%), Positives = 53/114 (46%), Gaps = 4/114 (3%)
Frame = +2
Query: 65 RRRNEVTVELRKNKREETL----QKRRNVPISYSTDEEEIDKNLATTDLDELVMNAANAE 232
RR+ V + + KR++ + RRN PI S D+E+ T+ ++++ + E
Sbjct: 4 RRKRAPPVRVDEEKRQQLHWNMHEDRRNEPIIISDDDEQPCPGSDTSSAHYIILSDSLKE 63
Query: 233 NPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAW 394
E ++C K++S K PI++ GI L L+ +P F+ +W
Sbjct: 64 --EVAHRDKKRCSKVVSFSK--PIEKEETVGIFSPLSVKLNIVISP-YHFDNSW 112
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 115,492,182
Number of Sequences: 237096
Number of extensions: 2686687
Number of successful extensions: 8035
Number of sequences better than 10.0: 94
Number of HSP's better than 10.0 without gapping: 6883
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7922
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8903143626
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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