Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= bmmt25k22
(666 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
CR541695-1|CAG46496.1| 414|Homo sapiens IDH1 protein. 309 7e-84
BC093020-1|AAH93020.1| 414|Homo sapiens isocitrate dehydrogenas... 309 7e-84
BC012846-1|AAH12846.1| 414|Homo sapiens IDH1 protein protein. 309 7e-84
AF113917-1|AAD29284.1| 414|Homo sapiens NADP+-dependent isocitr... 309 7e-84
AF020038-1|AAD02918.1| 414|Homo sapiens NADP-dependent isocitra... 309 7e-84
AC016697-3|AAX93221.1| 414|Homo sapiens unknown protein. 309 7e-84
CR533522-1|CAG38553.1| 414|Homo sapiens IDH1 protein. 308 1e-83
CR536499-1|CAG38738.1| 414|Homo sapiens IDH1 protein. 308 2e-83
BX537411-1|CAD97653.1| 414|Homo sapiens hypothetical protein pr... 307 3e-83
X69433-1|CAA49208.1| 452|Homo sapiens isocitrate dehydrogenase... 290 3e-78
BC071828-1|AAH71828.1| 452|Homo sapiens isocitrate dehydrogenas... 289 5e-78
BC009244-1|AAH09244.1| 452|Homo sapiens isocitrate dehydrogenas... 289 5e-78
AK222916-1|BAD96636.1| 452|Homo sapiens isocitrate dehydrogenas... 289 5e-78
DQ403082-1|ABD77215.1| 371|Homo sapiens isocitrate dehydrogenas... 269 7e-72
U52144-1|AAC50455.1| 419|Homo sapiens isocitrate dehydrogenase ... 243 5e-64
U62389-1|AAB17375.1| 154|Homo sapiens putative cytosolic NADP-d... 144 3e-34
BC020198-1|AAH20198.1| 567|Homo sapiens MEGF10 protein protein. 30 6.5
AB058676-1|BAB47409.1| 1140|Homo sapiens MEGF10 protein (KIAA178... 30 6.5
>CR541695-1|CAG46496.1| 414|Homo sapiens IDH1 protein.
Length = 414
Score = 309 bits (758), Expect = 7e-84
Identities = 142/197 (72%), Positives = 169/197 (85%), Gaps = 2/197 (1%)
Frame = +3
Query: 81 KIKAGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTIDCAEA 260
KI G VV++ GDEMTRIIW+LIKEKLI P+++++LH YDLG+ENRD T+DQVT D AEA
Sbjct: 4 KISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEA 63
Query: 261 IKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTG 440
IKK+NVG+KCATITPDEKRVEEFKLK+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+G
Sbjct: 64 IKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSG 123
Query: 441 WDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESG-EAIKHVVHEY-KGAGVALAMF 614
W KPIIIGRHA+ DQY+ATDFVVPG G +EI + P G + + ++VH + +G GVA+ M+
Sbjct: 124 WVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMY 183
Query: 615 NTDASIIDFAHSSFKFA 665
N D SI DFAHSSF+ A
Sbjct: 184 NQDKSIEDFAHSSFQMA 200
>BC093020-1|AAH93020.1| 414|Homo sapiens isocitrate dehydrogenase 1
(NADP+), soluble protein.
Length = 414
Score = 309 bits (758), Expect = 7e-84
Identities = 142/197 (72%), Positives = 169/197 (85%), Gaps = 2/197 (1%)
Frame = +3
Query: 81 KIKAGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTIDCAEA 260
KI G VV++ GDEMTRIIW+LIKEKLI P+++++LH YDLG+ENRD T+DQVT D AEA
Sbjct: 4 KISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEA 63
Query: 261 IKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTG 440
IKK+NVG+KCATITPDEKRVEEFKLK+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+G
Sbjct: 64 IKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSG 123
Query: 441 WDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESG-EAIKHVVHEY-KGAGVALAMF 614
W KPIIIGRHA+ DQY+ATDFVVPG G +EI + P G + + ++VH + +G GVA+ M+
Sbjct: 124 WVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMY 183
Query: 615 NTDASIIDFAHSSFKFA 665
N D SI DFAHSSF+ A
Sbjct: 184 NQDKSIEDFAHSSFQMA 200
>BC012846-1|AAH12846.1| 414|Homo sapiens IDH1 protein protein.
Length = 414
Score = 309 bits (758), Expect = 7e-84
Identities = 142/197 (72%), Positives = 169/197 (85%), Gaps = 2/197 (1%)
Frame = +3
Query: 81 KIKAGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTIDCAEA 260
KI G VV++ GDEMTRIIW+LIKEKLI P+++++LH YDLG+ENRD T+DQVT D AEA
Sbjct: 4 KISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEA 63
Query: 261 IKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTG 440
IKK+NVG+KCATITPDEKRVEEFKLK+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+G
Sbjct: 64 IKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSG 123
Query: 441 WDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESG-EAIKHVVHEY-KGAGVALAMF 614
W KPIIIGRHA+ DQY+ATDFVVPG G +EI + P G + + ++VH + +G GVA+ M+
Sbjct: 124 WVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMY 183
Query: 615 NTDASIIDFAHSSFKFA 665
N D SI DFAHSSF+ A
Sbjct: 184 NQDKSIEDFAHSSFQMA 200
>AF113917-1|AAD29284.1| 414|Homo sapiens NADP+-dependent isocitrate
dehydrogenase protein.
Length = 414
Score = 309 bits (758), Expect = 7e-84
Identities = 142/197 (72%), Positives = 169/197 (85%), Gaps = 2/197 (1%)
Frame = +3
Query: 81 KIKAGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTIDCAEA 260
KI G VV++ GDEMTRIIW+LIKEKLI P+++++LH YDLG+ENRD T+DQVT D AEA
Sbjct: 4 KISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEA 63
Query: 261 IKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTG 440
IKK+NVG+KCATITPDEKRVEEFKLK+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+G
Sbjct: 64 IKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSG 123
Query: 441 WDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESG-EAIKHVVHEY-KGAGVALAMF 614
W KPIIIGRHA+ DQY+ATDFVVPG G +EI + P G + + ++VH + +G GVA+ M+
Sbjct: 124 WVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMY 183
Query: 615 NTDASIIDFAHSSFKFA 665
N D SI DFAHSSF+ A
Sbjct: 184 NQDKSIEDFAHSSFQMA 200
>AF020038-1|AAD02918.1| 414|Homo sapiens NADP-dependent isocitrate
dehydrogenase protein.
Length = 414
Score = 309 bits (758), Expect = 7e-84
Identities = 142/197 (72%), Positives = 169/197 (85%), Gaps = 2/197 (1%)
Frame = +3
Query: 81 KIKAGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTIDCAEA 260
KI G VV++ GDEMTRIIW+LIKEKLI P+++++LH YDLG+ENRD T+DQVT D AEA
Sbjct: 4 KISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEA 63
Query: 261 IKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTG 440
IKK+NVG+KCATITPDEKRVEEFKLK+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+G
Sbjct: 64 IKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSG 123
Query: 441 WDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESG-EAIKHVVHEY-KGAGVALAMF 614
W KPIIIGRHA+ DQY+ATDFVVPG G +EI + P G + + ++VH + +G GVA+ M+
Sbjct: 124 WVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMY 183
Query: 615 NTDASIIDFAHSSFKFA 665
N D SI DFAHSSF+ A
Sbjct: 184 NQDKSIEDFAHSSFQMA 200
>AC016697-3|AAX93221.1| 414|Homo sapiens unknown protein.
Length = 414
Score = 309 bits (758), Expect = 7e-84
Identities = 142/197 (72%), Positives = 169/197 (85%), Gaps = 2/197 (1%)
Frame = +3
Query: 81 KIKAGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTIDCAEA 260
KI G VV++ GDEMTRIIW+LIKEKLI P+++++LH YDLG+ENRD T+DQVT D AEA
Sbjct: 4 KISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEA 63
Query: 261 IKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTG 440
IKK+NVG+KCATITPDEKRVEEFKLK+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+G
Sbjct: 64 IKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSG 123
Query: 441 WDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESG-EAIKHVVHEY-KGAGVALAMF 614
W KPIIIGRHA+ DQY+ATDFVVPG G +EI + P G + + ++VH + +G GVA+ M+
Sbjct: 124 WVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMY 183
Query: 615 NTDASIIDFAHSSFKFA 665
N D SI DFAHSSF+ A
Sbjct: 184 NQDKSIEDFAHSSFQMA 200
>CR533522-1|CAG38553.1| 414|Homo sapiens IDH1 protein.
Length = 414
Score = 308 bits (756), Expect = 1e-83
Identities = 141/197 (71%), Positives = 170/197 (86%), Gaps = 2/197 (1%)
Frame = +3
Query: 81 KIKAGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTIDCAEA 260
KI G VV++ GDEMTRIIW+LIKEKLI+P+++++LH YDLG+ENRD T+DQVT D AEA
Sbjct: 4 KISGGSVVEMQGDEMTRIIWELIKEKLIIPYVELDLHSYDLGIENRDATNDQVTKDAAEA 63
Query: 261 IKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTG 440
IKK+NVG+KCATITPDEKRVEEFKLK+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+G
Sbjct: 64 IKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSG 123
Query: 441 WDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESG-EAIKHVVHEY-KGAGVALAMF 614
W +PIIIGRHA+ DQY+ATDFVVPG G +EI + P G + + ++VH + +G GVA+ M+
Sbjct: 124 WVEPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMY 183
Query: 615 NTDASIIDFAHSSFKFA 665
N D SI DFAHSSF+ A
Sbjct: 184 NQDKSIEDFAHSSFQMA 200
>CR536499-1|CAG38738.1| 414|Homo sapiens IDH1 protein.
Length = 414
Score = 308 bits (755), Expect = 2e-83
Identities = 141/197 (71%), Positives = 169/197 (85%), Gaps = 2/197 (1%)
Frame = +3
Query: 81 KIKAGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTIDCAEA 260
KI G VV++ GDEMTRIIW+LIKEKLI P+++++LH YDLG+ENRD T+DQVT D AEA
Sbjct: 4 KISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEA 63
Query: 261 IKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTG 440
IKK+NVG+KCATITPDEKRVEEFKLK+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+G
Sbjct: 64 IKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSG 123
Query: 441 WDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESG-EAIKHVVHEY-KGAGVALAMF 614
W KPIIIGRHA+ DQY+ATDFVVPG G +E+ + P G + + ++VH + +G GVA+ M+
Sbjct: 124 WVKPIIIGRHAYGDQYRATDFVVPGPGKVEMTYTPSDGTQKVTYLVHNFEEGGGVAMGMY 183
Query: 615 NTDASIIDFAHSSFKFA 665
N D SI DFAHSSF+ A
Sbjct: 184 NQDKSIEDFAHSSFQMA 200
>BX537411-1|CAD97653.1| 414|Homo sapiens hypothetical protein
protein.
Length = 414
Score = 307 bits (753), Expect = 3e-83
Identities = 142/197 (72%), Positives = 168/197 (85%), Gaps = 2/197 (1%)
Frame = +3
Query: 81 KIKAGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQVTIDCAEA 260
KI G VV++ GDEMTRIIW+LIKEKLI P+++++LH YDLG+ENRD T+DQVT D AEA
Sbjct: 4 KISGGSVVEMQGDEMTRIIWELIKEKLIFPYVELDLHSYDLGIENRDATNDQVTKDAAEA 63
Query: 261 IKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICKNIPRLVTG 440
IKK+NVG+KCATITPDEKRVEEFKLK+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+G
Sbjct: 64 IKKHNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRLVSG 123
Query: 441 WDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESG-EAIKHVVHEYK-GAGVALAMF 614
W KPIIIGRHA+ DQY+ATDFVVPG G +EI + P G + + ++VH + G GVA+ M+
Sbjct: 124 WVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPSDGTQKVTYLVHNSEGGGGVAMGMY 183
Query: 615 NTDASIIDFAHSSFKFA 665
N D SI DFAHSSF+ A
Sbjct: 184 NQDKSIEDFAHSSFQMA 200
>X69433-1|CAA49208.1| 452|Homo sapiens isocitrate dehydrogenase
(NADP+) protein.
Length = 452
Score = 290 bits (711), Expect = 3e-78
Identities = 137/206 (66%), Positives = 160/206 (77%), Gaps = 2/206 (0%)
Frame = +3
Query: 54 YSRHRYNMSKIK-AGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTD 230
+ R Y +IK A PVV++ GDEMTRIIW IKEKLILP +DI+L +DLG+ NRD+TD
Sbjct: 34 HPRRHYADKRIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTD 93
Query: 231 DQVTIDCAEAIKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAII 410
DQVTID A A +KY+V +KCATITPDE RVEEFKLKKMWKSPNGTIRNILGGTVFRE II
Sbjct: 94 DQVTIDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPII 153
Query: 411 CKNIPRLVTGWDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESGEAIKH-VVHEYK 587
CKNIPRLV GW KPI IGRHAH DQYKATDFV AGT +++F P+ G +K V+ +
Sbjct: 154 CKNIPRLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFP 213
Query: 588 GAGVALAMFNTDASIIDFAHSSFKFA 665
GV + M+NTD SI FAHS F++A
Sbjct: 214 AGGVGMGMYNTDESISGFAHSCFQYA 239
>BC071828-1|AAH71828.1| 452|Homo sapiens isocitrate dehydrogenase 2
(NADP+), mitochondrial protein.
Length = 452
Score = 289 bits (710), Expect = 5e-78
Identities = 137/204 (67%), Positives = 159/204 (77%), Gaps = 2/204 (0%)
Frame = +3
Query: 60 RHRYNMSKIK-AGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQ 236
R Y +IK A PVV++ GDEMTRIIW IKEKLILP +DI+L +DLG+ NRD+TDDQ
Sbjct: 36 RRHYADKRIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQ 95
Query: 237 VTIDCAEAIKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICK 416
VTID A A +KY+V +KCATITPDE RVEEFKLKKMWKSPNGTIRNILGGTVFRE IICK
Sbjct: 96 VTIDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICK 155
Query: 417 NIPRLVTGWDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESGEAIKH-VVHEYKGA 593
NIPRLV GW KPI IGRHAH DQYKATDFV AGT +++F P+ G +K V+ +
Sbjct: 156 NIPRLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAG 215
Query: 594 GVALAMFNTDASIIDFAHSSFKFA 665
GV + M+NTD SI FAHS F++A
Sbjct: 216 GVGMGMYNTDESISGFAHSCFQYA 239
>BC009244-1|AAH09244.1| 452|Homo sapiens isocitrate dehydrogenase 2
(NADP+), mitochondrial protein.
Length = 452
Score = 289 bits (710), Expect = 5e-78
Identities = 137/204 (67%), Positives = 159/204 (77%), Gaps = 2/204 (0%)
Frame = +3
Query: 60 RHRYNMSKIK-AGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQ 236
R Y +IK A PVV++ GDEMTRIIW IKEKLILP +DI+L +DLG+ NRD+TDDQ
Sbjct: 36 RRHYADKRIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQ 95
Query: 237 VTIDCAEAIKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICK 416
VTID A A +KY+V +KCATITPDE RVEEFKLKKMWKSPNGTIRNILGGTVFRE IICK
Sbjct: 96 VTIDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICK 155
Query: 417 NIPRLVTGWDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESGEAIKH-VVHEYKGA 593
NIPRLV GW KPI IGRHAH DQYKATDFV AGT +++F P+ G +K V+ +
Sbjct: 156 NIPRLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAG 215
Query: 594 GVALAMFNTDASIIDFAHSSFKFA 665
GV + M+NTD SI FAHS F++A
Sbjct: 216 GVGMGMYNTDESISGFAHSCFQYA 239
>AK222916-1|BAD96636.1| 452|Homo sapiens isocitrate dehydrogenase 2
(NADP+), mitochondrial precursor variant protein.
Length = 452
Score = 289 bits (710), Expect = 5e-78
Identities = 137/204 (67%), Positives = 159/204 (77%), Gaps = 2/204 (0%)
Frame = +3
Query: 60 RHRYNMSKIK-AGPVVDILGDEMTRIIWDLIKEKLILPFLDIELHVYDLGMENRDKTDDQ 236
R Y +IK A PVV++ GDEMTRIIW IKEKLILP +DI+L +DLG+ NRD+TDDQ
Sbjct: 36 RRHYADKRIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQ 95
Query: 237 VTIDCAEAIKKYNVGIKCATITPDEKRVEEFKLKKMWKSPNGTIRNILGGTVFREAIICK 416
VTID A A +KY+V +KCATITPDE RVEEFKLKKMWKSPNGTIRNILGGTVFRE IICK
Sbjct: 96 VTIDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICK 155
Query: 417 NIPRLVTGWDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPESGEAIKH-VVHEYKGA 593
NIPRLV GW KPI IGRHAH DQYKATDFV AGT +++F P+ G +K V+ +
Sbjct: 156 NIPRLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFPAG 215
Query: 594 GVALAMFNTDASIIDFAHSSFKFA 665
GV + M+NTD SI FAHS F++A
Sbjct: 216 GVGMGMYNTDESISGFAHSCFQYA 239
>DQ403082-1|ABD77215.1| 371|Homo sapiens isocitrate dehydrogenase 1
protein.
Length = 371
Score = 269 bits (659), Expect = 7e-72
Identities = 123/171 (71%), Positives = 147/171 (85%), Gaps = 2/171 (1%)
Frame = +3
Query: 159 LILPFLDIELHVYDLGMENRDKTDDQVTIDCAEAIKKYNVGIKCATITPDEKRVEEFKLK 338
LI P+++++LH YDLG+ENRD T+DQVT D AEAIKK+NVG+KCATITPDEKRVEEFKLK
Sbjct: 1 LIFPYVELDLHSYDLGIENRDATNDQVTKDAAEAIKKHNVGVKCATITPDEKRVEEFKLK 60
Query: 339 KMWKSPNGTIRNILGGTVFREAIICKNIPRLVTGWDKPIIIGRHAHADQYKATDFVVPGA 518
+MWKSPNGTIRNILGGTVFREAIICKNIPRLV+GW KPIIIGRHA+ DQY+ATDFVVPG
Sbjct: 61 QMWKSPNGTIRNILGGTVFREAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGP 120
Query: 519 GTLEIIFKPESG-EAIKHVVHEY-KGAGVALAMFNTDASIIDFAHSSFKFA 665
G +EI + P G + + ++VH + +G GVA+ M+N D SI DFAHSSF+ A
Sbjct: 121 GKVEITYTPSDGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMA 171
>U52144-1|AAC50455.1| 419|Homo sapiens isocitrate dehydrogenase
protein.
Length = 419
Score = 243 bits (594), Expect = 5e-64
Identities = 111/165 (67%), Positives = 130/165 (78%), Gaps = 1/165 (0%)
Frame = +3
Query: 174 LDIELHVYDLGMENRDKTDDQVTIDCAEAIKKYNVGIKCATITPDEKRVEEFKLKKMWKS 353
LD++L +DLG+ NRD+TDDQVTID A A +KY+V +KCATITPDE RVEEFKLKKMWKS
Sbjct: 42 LDVQLKYFDLGLPNRDQTDDQVTIDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKS 101
Query: 354 PNGTIRNILGGTVFREAIICKNIPRLVTGWDKPIIIGRHAHADQYKATDFVVPGAGTLEI 533
PNGTIRNI GGTVFRE IICKNIPRLV GW KPI IGRHAH DQYKATDFV AGT ++
Sbjct: 102 PNGTIRNIHGGTVFREPIICKNIPRLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKM 161
Query: 534 IFKPESGEAIKH-VVHEYKGAGVALAMFNTDASIIDFAHSSFKFA 665
+F P+ G +K V+ + GV + M+NTD SI FAHS F++A
Sbjct: 162 VFTPKDGSGVKEWEVYNFPAGGVGMGMYNTDESISGFAHSCFQYA 206
>U62389-1|AAB17375.1| 154|Homo sapiens putative cytosolic
NADP-dependent isocitrate dehydrogenase protein.
Length = 154
Score = 144 bits (348), Expect = 3e-34
Identities = 67/101 (66%), Positives = 81/101 (80%), Gaps = 2/101 (1%)
Frame = +3
Query: 369 RNILGGTVFREAIICKNIPRLVTGWDKPIIIGRHAHADQYKATDFVVPGAGTLEIIFKPE 548
RNILGGTVF EAIICKNIPRLV+GW KPIIIGRHA+ DQY+ATDFVVPG G +EI + P
Sbjct: 1 RNILGGTVFXEAIICKNIPRLVSGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPS 60
Query: 549 SG-EAIKHVVHEY-KGAGVALAMFNTDASIIDFAHSSFKFA 665
G + + ++VH + +G GVA+ M+N D SI DFAHSSF+ A
Sbjct: 61 DGTQKVTYLVHNFEEGGGVAMGMYNQDKSIEDFAHSSFQMA 101
>BC020198-1|AAH20198.1| 567|Homo sapiens MEGF10 protein protein.
Length = 567
Score = 30.3 bits (65), Expect = 6.5
Identities = 21/68 (30%), Positives = 24/68 (35%), Gaps = 3/68 (4%)
Frame = +2
Query: 431 CNRVGQTHHHWTSCSC*SIQSN*LC---CPRCWYS*NNLQT*IW*GNKTCSS*VQGCRCS 601
C G HH CSC S +C CP + N Q TC + C CS
Sbjct: 240 CQNGGVCHHVTGECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHNGGTCDAATGQCHCS 299
Query: 602 TGYV*H*C 625
GY C
Sbjct: 300 PGYTGERC 307
>AB058676-1|BAB47409.1| 1140|Homo sapiens MEGF10 protein (KIAA1780)
protein.
Length = 1140
Score = 30.3 bits (65), Expect = 6.5
Identities = 21/68 (30%), Positives = 24/68 (35%), Gaps = 3/68 (4%)
Frame = +2
Query: 431 CNRVGQTHHHWTSCSC*SIQSN*LC---CPRCWYS*NNLQT*IW*GNKTCSS*VQGCRCS 601
C G HH CSC S +C CP + N Q TC + C CS
Sbjct: 240 CQNGGVCHHVTGECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHNGGTCDAATGQCHCS 299
Query: 602 TGYV*H*C 625
GY C
Sbjct: 300 PGYTGERC 307
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 93,808,407
Number of Sequences: 237096
Number of extensions: 2125159
Number of successful extensions: 3890
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 3731
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3868
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 7535049140
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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