Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= bmmt25i24
(655 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC000038-1|AAH00038.1| 423|Homo sapiens sphingomyelin phosphodi... 131 2e-30
AL109947-3|CAI23338.1| 423|Homo sapiens sphingomyelin phosphodi... 131 2e-30
AJ222801-1|CAA10995.1| 423|Homo sapiens neutral sphingomyelinas... 131 2e-30
AL109947-4|CAI23340.1| 77|Homo sapiens sphingomyelin phosphodi... 74 5e-13
U08316-1|AAA81952.1| 740|Homo sapiens insulin-stimulated protei... 31 4.7
DQ424899-1|ABD83664.1| 638|Homo sapiens sphingomyelin phosphodi... 31 4.7
CR536566-1|CAG38803.1| 745|Homo sapiens RPS6KA6 protein. 31 4.7
BC112238-1|AAI12239.1| 655|Homo sapiens sphingomyelin phosphodi... 31 4.7
BC096303-1|AAH96303.1| 740|Homo sapiens ribosomal protein S6 ki... 31 4.7
BC096302-1|AAH96302.1| 740|Homo sapiens ribosomal protein S6 ki... 31 4.7
BC096301-1|AAH96301.1| 740|Homo sapiens ribosomal protein S6 ki... 31 4.7
AL807772-3|CAI39687.1| 740|Homo sapiens ribosomal protein S6 ki... 31 4.7
AL732366-2|CAI40548.1| 740|Homo sapiens ribosomal protein S6 ki... 31 4.7
AL389887-1|CAC16111.2| 745|Homo sapiens ribosomal protein S6 ki... 31 4.7
AL354653-1|CAD13486.2| 745|Homo sapiens ribosomal protein S6 ki... 31 4.7
AJ250460-1|CAB92964.1| 655|Homo sapiens neutral sphingomyelinas... 31 4.7
AF184965-1|AAF13190.1| 745|Homo sapiens ribosomal S6 kinase pro... 31 4.7
AB208933-1|BAD92170.1| 806|Homo sapiens ribosomal protein S6 ki... 31 4.7
AB102662-1|BAC81131.1| 726|Homo sapiens RPS6KA3 protein. 31 4.7
>BC000038-1|AAH00038.1| 423|Homo sapiens sphingomyelin
phosphodiesterase 2, neutral membrane (neutral
sphingomyelinase) protein.
Length = 423
Score = 131 bits (316), Expect = 2e-30
Identities = 55/113 (48%), Positives = 78/113 (69%)
Frame = +2
Query: 263 LNIFTLNCWGIPVVSKNKKERYEAISTYLLKSEHNIVCLQEVWSEKDYLYLKENLKNVLP 442
L IF LNCWGIP +SK++ +R + +L + ++ L+EVWSE+D+ YL++ L P
Sbjct: 9 LRIFNLNCWGIPYLSKHRADRMRRLGDFLNQESFDLALLEEVWSEQDFQYLRQKLSPTYP 68
Query: 443 YSYYFYSGVLGSGLCVFSKWVIQDVFFHQWPLNGYIHKIHHGDWFGGKRCGSL 601
+++F SG++GSGLCVFSK IQ++ H + LNGY + IHHGDWF GK G L
Sbjct: 69 AAHHFRSGIIGSGLCVFSKHPIQELTQHIYTLNGYPYMIHHGDWFSGKAVGLL 121
>AL109947-3|CAI23338.1| 423|Homo sapiens sphingomyelin
phosphodiesterase 2, neutral membrane (neutral
sphingomyelinase) protein.
Length = 423
Score = 131 bits (316), Expect = 2e-30
Identities = 55/113 (48%), Positives = 78/113 (69%)
Frame = +2
Query: 263 LNIFTLNCWGIPVVSKNKKERYEAISTYLLKSEHNIVCLQEVWSEKDYLYLKENLKNVLP 442
L IF LNCWGIP +SK++ +R + +L + ++ L+EVWSE+D+ YL++ L P
Sbjct: 9 LRIFNLNCWGIPYLSKHRADRMRRLGDFLNQESFDLALLEEVWSEQDFQYLRQKLSPTYP 68
Query: 443 YSYYFYSGVLGSGLCVFSKWVIQDVFFHQWPLNGYIHKIHHGDWFGGKRCGSL 601
+++F SG++GSGLCVFSK IQ++ H + LNGY + IHHGDWF GK G L
Sbjct: 69 AAHHFRSGIIGSGLCVFSKHPIQELTQHIYTLNGYPYMIHHGDWFSGKAVGLL 121
>AJ222801-1|CAA10995.1| 423|Homo sapiens neutral sphingomyelinase
protein.
Length = 423
Score = 131 bits (316), Expect = 2e-30
Identities = 55/113 (48%), Positives = 78/113 (69%)
Frame = +2
Query: 263 LNIFTLNCWGIPVVSKNKKERYEAISTYLLKSEHNIVCLQEVWSEKDYLYLKENLKNVLP 442
L IF LNCWGIP +SK++ +R + +L + ++ L+EVWSE+D+ YL++ L P
Sbjct: 9 LRIFNLNCWGIPYLSKHRADRMRRLGDFLNQESFDLALLEEVWSEQDFQYLRQKLSPTYP 68
Query: 443 YSYYFYSGVLGSGLCVFSKWVIQDVFFHQWPLNGYIHKIHHGDWFGGKRCGSL 601
+++F SG++GSGLCVFSK IQ++ H + LNGY + IHHGDWF GK G L
Sbjct: 69 AAHHFRSGIIGSGLCVFSKHPIQELTQHIYTLNGYPYMIHHGDWFSGKAVGLL 121
>AL109947-4|CAI23340.1| 77|Homo sapiens sphingomyelin
phosphodiesterase 2, neutral membrane (neutral
sphingomyelinase) protein.
Length = 77
Score = 73.7 bits (173), Expect = 5e-13
Identities = 31/54 (57%), Positives = 40/54 (74%)
Frame = +2
Query: 440 PYSYYFYSGVLGSGLCVFSKWVIQDVFFHQWPLNGYIHKIHHGDWFGGKRCGSL 601
P +++F SG++GSGLCVFSK IQ++ H + LNGY + IHHGDWF GK G L
Sbjct: 2 PAAHHFRSGIIGSGLCVFSKHPIQELTQHIYTLNGYPYMIHHGDWFSGKAVGLL 55
>U08316-1|AAA81952.1| 740|Homo sapiens insulin-stimulated protein
kinase 1 protein.
Length = 740
Score = 30.7 bits (66), Expect = 4.7
Identities = 13/48 (27%), Positives = 28/48 (58%), Gaps = 1/48 (2%)
Frame = +2
Query: 287 WGIPVVSKNKKERYEAISTYLLKSEH-NIVCLQEVWSEKDYLYLKENL 427
+ + ++ K+K++ E I L +H NI+ L++V+ + Y+Y+ L
Sbjct: 448 FAVKIIDKSKRDPTEEIEILLRYGQHPNIITLKDVYDDGKYVYVVTEL 495
>DQ424899-1|ABD83664.1| 638|Homo sapiens sphingomyelin
phosphodiesterase 3 protein.
Length = 638
Score = 30.7 bits (66), Expect = 4.7
Identities = 22/67 (32%), Positives = 31/67 (46%), Gaps = 10/67 (14%)
Frame = +2
Query: 365 NIVCLQEVWSEKDYLYLKENLKNVLPYSYY---FYS-------GVLGSGLCVFSKWVIQD 514
+ +CLQEV+ ++ LKE L Y Y Y L SGL S++ I D
Sbjct: 358 DFLCLQEVFDKRAATKLKEQLHGYFEYILYDVGVYGCQGCCSFKCLNSGLLFASRYPIMD 417
Query: 515 VFFHQWP 535
V +H +P
Sbjct: 418 VAYHCYP 424
>CR536566-1|CAG38803.1| 745|Homo sapiens RPS6KA6 protein.
Length = 745
Score = 30.7 bits (66), Expect = 4.7
Identities = 13/48 (27%), Positives = 29/48 (60%), Gaps = 1/48 (2%)
Frame = +2
Query: 287 WGIPVVSKNKKERYEAISTYLLKSEH-NIVCLQEVWSEKDYLYLKENL 427
+ + ++ K+K++ E I + +H NI+ L++V+ + Y+YL +L
Sbjct: 452 FAVKIIDKSKRDPSEEIEILMRYGQHPNIITLKDVFDDGRYVYLVTDL 499
>BC112238-1|AAI12239.1| 655|Homo sapiens sphingomyelin
phosphodiesterase 3, neutral membrane protein.
Length = 655
Score = 30.7 bits (66), Expect = 4.7
Identities = 22/67 (32%), Positives = 31/67 (46%), Gaps = 10/67 (14%)
Frame = +2
Query: 365 NIVCLQEVWSEKDYLYLKENLKNVLPYSYY---FYS-------GVLGSGLCVFSKWVIQD 514
+ +CLQEV+ ++ LKE L Y Y Y L SGL S++ I D
Sbjct: 358 DFLCLQEVFDKRAATKLKEQLHGYFEYILYDVGVYGCQGCCSFKCLNSGLLFASRYPIMD 417
Query: 515 VFFHQWP 535
V +H +P
Sbjct: 418 VAYHCYP 424
>BC096303-1|AAH96303.1| 740|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 protein.
Length = 740
Score = 30.7 bits (66), Expect = 4.7
Identities = 13/48 (27%), Positives = 28/48 (58%), Gaps = 1/48 (2%)
Frame = +2
Query: 287 WGIPVVSKNKKERYEAISTYLLKSEH-NIVCLQEVWSEKDYLYLKENL 427
+ + ++ K+K++ E I L +H NI+ L++V+ + Y+Y+ L
Sbjct: 448 FAVKIIDKSKRDPTEEIEILLRYGQHPNIITLKDVYDDGKYVYVVTEL 495
>BC096302-1|AAH96302.1| 740|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 protein.
Length = 740
Score = 30.7 bits (66), Expect = 4.7
Identities = 13/48 (27%), Positives = 28/48 (58%), Gaps = 1/48 (2%)
Frame = +2
Query: 287 WGIPVVSKNKKERYEAISTYLLKSEH-NIVCLQEVWSEKDYLYLKENL 427
+ + ++ K+K++ E I L +H NI+ L++V+ + Y+Y+ L
Sbjct: 448 FAVKIIDKSKRDPTEEIEILLRYGQHPNIITLKDVYDDGKYVYVVTEL 495
>BC096301-1|AAH96301.1| 740|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 protein.
Length = 740
Score = 30.7 bits (66), Expect = 4.7
Identities = 13/48 (27%), Positives = 28/48 (58%), Gaps = 1/48 (2%)
Frame = +2
Query: 287 WGIPVVSKNKKERYEAISTYLLKSEH-NIVCLQEVWSEKDYLYLKENL 427
+ + ++ K+K++ E I L +H NI+ L++V+ + Y+Y+ L
Sbjct: 448 FAVKIIDKSKRDPTEEIEILLRYGQHPNIITLKDVYDDGKYVYVVTEL 495
>AL807772-3|CAI39687.1| 740|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 protein.
Length = 740
Score = 30.7 bits (66), Expect = 4.7
Identities = 13/48 (27%), Positives = 28/48 (58%), Gaps = 1/48 (2%)
Frame = +2
Query: 287 WGIPVVSKNKKERYEAISTYLLKSEH-NIVCLQEVWSEKDYLYLKENL 427
+ + ++ K+K++ E I L +H NI+ L++V+ + Y+Y+ L
Sbjct: 448 FAVKIIDKSKRDPTEEIEILLRYGQHPNIITLKDVYDDGKYVYVVTEL 495
>AL732366-2|CAI40548.1| 740|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 protein.
Length = 740
Score = 30.7 bits (66), Expect = 4.7
Identities = 13/48 (27%), Positives = 28/48 (58%), Gaps = 1/48 (2%)
Frame = +2
Query: 287 WGIPVVSKNKKERYEAISTYLLKSEH-NIVCLQEVWSEKDYLYLKENL 427
+ + ++ K+K++ E I L +H NI+ L++V+ + Y+Y+ L
Sbjct: 448 FAVKIIDKSKRDPTEEIEILLRYGQHPNIITLKDVYDDGKYVYVVTEL 495
>AL389887-1|CAC16111.2| 745|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 6 protein.
Length = 745
Score = 30.7 bits (66), Expect = 4.7
Identities = 13/48 (27%), Positives = 29/48 (60%), Gaps = 1/48 (2%)
Frame = +2
Query: 287 WGIPVVSKNKKERYEAISTYLLKSEH-NIVCLQEVWSEKDYLYLKENL 427
+ + ++ K+K++ E I + +H NI+ L++V+ + Y+YL +L
Sbjct: 452 FAVKIIDKSKRDPSEEIEILMRYGQHPNIITLKDVFDDGRYVYLVTDL 499
>AL354653-1|CAD13486.2| 745|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 6 protein.
Length = 745
Score = 30.7 bits (66), Expect = 4.7
Identities = 13/48 (27%), Positives = 29/48 (60%), Gaps = 1/48 (2%)
Frame = +2
Query: 287 WGIPVVSKNKKERYEAISTYLLKSEH-NIVCLQEVWSEKDYLYLKENL 427
+ + ++ K+K++ E I + +H NI+ L++V+ + Y+YL +L
Sbjct: 452 FAVKIIDKSKRDPSEEIEILMRYGQHPNIITLKDVFDDGRYVYLVTDL 499
>AJ250460-1|CAB92964.1| 655|Homo sapiens neutral sphingomyelinase
II protein.
Length = 655
Score = 30.7 bits (66), Expect = 4.7
Identities = 22/67 (32%), Positives = 31/67 (46%), Gaps = 10/67 (14%)
Frame = +2
Query: 365 NIVCLQEVWSEKDYLYLKENLKNVLPYSYY---FYS-------GVLGSGLCVFSKWVIQD 514
+ +CLQEV+ ++ LKE L Y Y Y L SGL S++ I D
Sbjct: 358 DFLCLQEVFDKRAATKLKEQLHGYFEYILYDVGVYGCQGCCSFKCLNSGLLFASRYPIMD 417
Query: 515 VFFHQWP 535
V +H +P
Sbjct: 418 VAYHCYP 424
>AF184965-1|AAF13190.1| 745|Homo sapiens ribosomal S6 kinase
protein.
Length = 745
Score = 30.7 bits (66), Expect = 4.7
Identities = 13/48 (27%), Positives = 29/48 (60%), Gaps = 1/48 (2%)
Frame = +2
Query: 287 WGIPVVSKNKKERYEAISTYLLKSEH-NIVCLQEVWSEKDYLYLKENL 427
+ + ++ K+K++ E I + +H NI+ L++V+ + Y+YL +L
Sbjct: 452 FAVKIIDKSKRDPSEEIEILMRYGQHPNIITLKDVFDDGRYVYLVTDL 499
>AB208933-1|BAD92170.1| 806|Homo sapiens ribosomal protein S6
kinase, 90kDa, polypeptide 3 variant protein.
Length = 806
Score = 30.7 bits (66), Expect = 4.7
Identities = 13/48 (27%), Positives = 28/48 (58%), Gaps = 1/48 (2%)
Frame = +2
Query: 287 WGIPVVSKNKKERYEAISTYLLKSEH-NIVCLQEVWSEKDYLYLKENL 427
+ + ++ K+K++ E I L +H NI+ L++V+ + Y+Y+ L
Sbjct: 514 FAVKIIDKSKRDPTEEIEILLRYGQHPNIITLKDVYDDGKYVYVVTEL 561
>AB102662-1|BAC81131.1| 726|Homo sapiens RPS6KA3 protein.
Length = 726
Score = 30.7 bits (66), Expect = 4.7
Identities = 13/48 (27%), Positives = 28/48 (58%), Gaps = 1/48 (2%)
Frame = +2
Query: 287 WGIPVVSKNKKERYEAISTYLLKSEH-NIVCLQEVWSEKDYLYLKENL 427
+ + ++ K+K++ E I L +H NI+ L++V+ + Y+Y+ L
Sbjct: 434 FAVKIIDKSKRDPTEEIEILLRYGQHPNIITLKDVYDDGKYVYVVTEL 481
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 95,129,795
Number of Sequences: 237096
Number of extensions: 2147977
Number of successful extensions: 4422
Number of sequences better than 10.0: 19
Number of HSP's better than 10.0 without gapping: 4214
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4408
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 7310122300
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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