Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= bmmt25f14
(699 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X07994-1|CAA30801.1| 1927|Homo sapiens protein ( Human mRNA for ... 199 9e-51
AY191611-1|AAP12677.1| 1003|Homo sapiens lactase-phlorizin hydro... 199 9e-51
M61850-1|AAA59504.1| 1927|Homo sapiens lactase phlorizinhydrolas... 197 3e-50
AC011893-3|AAX88924.1| 1927|Homo sapiens unknown protein. 197 3e-50
BC101829-1|AAI01830.1| 469|Homo sapiens cytosolic beta-glucosid... 180 6e-45
AK222963-1|BAD96683.1| 469|Homo sapiens cytosolic beta-glucosid... 180 6e-45
AJ278964-1|CAC08178.1| 469|Homo sapiens cytosolic beta-glucosid... 180 6e-45
AF323990-1|AAL37305.1| 469|Homo sapiens cytosolic beta-glucosid... 180 6e-45
AB017913-1|BAB18741.1| 469|Homo sapiens cytosolic beta-glucosid... 180 6e-45
AF317840-1|AAG39217.1| 469|Homo sapiens cytosolic beta-glucosid... 179 1e-44
AY358729-1|AAQ89091.1| 567|Homo sapiens KPVW3022 protein. 171 3e-42
BC113653-1|AAI13654.1| 1044|Homo sapiens klotho beta protein. 163 7e-40
BC104871-1|AAI04872.1| 1044|Homo sapiens klotho beta protein. 163 7e-40
AB079373-1|BAC56857.1| 1044|Homo sapiens klotho beta like protei... 163 7e-40
Z92540-2|CAC94767.1| 273|Homo sapiens 179I15.1 (klotho) protein. 142 1e-33
AL161898-1|CAH71888.1| 1012|Homo sapiens klotho protein. 142 1e-33
AB009667-2|BAA24941.1| 549|Homo sapiens Klotho protein (KL) pro... 142 1e-33
AB009667-1|BAA24940.1| 1012|Homo sapiens Klotho protein (KL) pro... 142 1e-33
AB005142-1|BAA23382.1| 1012|Homo sapiens klotho protein. 142 1e-33
BC109377-1|AAI09378.1| 162|Homo sapiens GBA3 protein protein. 101 3e-21
BC029362-1|AAH29362.1| 162|Homo sapiens GBA3 protein protein. 101 3e-21
BC070188-1|AAH70188.1| 162|Homo sapiens GBA3 protein protein. 97 5e-20
Z84483-1|CAC94773.1| 739|Homo sapiens 46H23.1 (Klotho) protein. 79 2e-14
BC111769-1|AAI11770.1| 177|Homo sapiens FLJ40448 protein protein. 34 0.42
AK097767-1|BAC05165.1| 185|Homo sapiens protein ( Homo sapiens ... 34 0.42
U94777-1|AAC52081.1| 842|Homo sapiens muscle glycogen phosphory... 33 0.98
M32598-1|AAA60231.1| 842|Homo sapiens PYGM protein. 33 0.98
BC130514-1|AAI30515.1| 842|Homo sapiens phosphorylase, glycogen... 33 0.98
BC126392-1|AAI26393.1| 842|Homo sapiens phosphorylase, glycogen... 33 0.98
AF066859-1|AAC17451.1| 842|Homo sapiens muscle glycogen phospho... 33 0.98
U47025-1|AAB60395.1| 843|Homo sapiens glycogen phosphorylase B ... 32 2.3
J03544-1|AAA59597.1| 863|Homo sapiens PYGB protein. 32 2.3
BC030795-1|AAH30795.1| 843|Homo sapiens phosphorylase, glycogen... 32 2.3
BC017045-1|AAH17045.1| 843|Homo sapiens phosphorylase, glycogen... 32 2.3
AL121772-1|CAC00661.1| 843|Homo sapiens phosphorylase, glycogen... 32 2.3
AB209080-1|BAD92317.1| 865|Homo sapiens brain glycogen phosphor... 32 2.3
AK131337-1|BAD18495.1| 646|Homo sapiens protein ( Homo sapiens ... 31 3.0
AM079743-1|CAL03889.1| 101|Homo sapiens immunoglobulin heavy ch... 31 4.0
>X07994-1|CAA30801.1| 1927|Homo sapiens protein ( Human mRNA for
lactase-phlorizin hydrolase LPH (EC 3.2.1.23-62). ).
Length = 1927
Score = 199 bits (485), Expect = 9e-51
Identities = 88/192 (45%), Positives = 123/192 (64%), Gaps = 4/192 (2%)
Frame = +1
Query: 52 FKFGAATSSYQIEGSWNVSDKTPSTWDDYTHTQPHRIKDHSNGDVACDSYNQYEKDIEMA 231
F +G ++S+YQIEG+W+ K PS WD++THT +KD++ GD+ACDSY+Q + D+ M
Sbjct: 907 FLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYHQLDADLNML 966
Query: 232 EQLGLDFYRFSISWPRLLPKGFRTRISADGRQYYDNLINGLLDRGIEPMVTLYHSDMPKI 411
L + YRFSISW R+ P G + I++ G YY+ LINGL+ I PMVTL+H D+P+
Sbjct: 967 RALKVKAYRFSISWSRIFPTGRNSSINSHGVDYYNRLINGLVASNIFPMVTLFHWDLPQA 1026
Query: 412 FQDLGGWANPEMAEWFADYADVAFSLYGDRVKLWITINEPLHAC----DSSSRVLGVVEP 579
QD+GGW NP + + F YAD F +GDRVK W+T NEP++ S GV +P
Sbjct: 1027 LQDIGGWENPALIDLFDSYADFCFQTFGDRVKFWMTFNEPMYLAWLGYGSGEFPPGVKDP 1086
Query: 580 FLAPYLCTKTLL 615
APY T++
Sbjct: 1087 GWAPYRIAHTVI 1098
Score = 177 bits (431), Expect = 3e-44
Identities = 79/164 (48%), Positives = 109/164 (66%)
Frame = +1
Query: 40 FPRWFKFGAATSSYQIEGSWNVSDKTPSTWDDYTHTQPHRIKDHSNGDVACDSYNQYEKD 219
FP F + AA+++YQIEG+W K S WD ++HT P R+++ + GDVACDSY++ +D
Sbjct: 1377 FPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSHT-PLRVENDAIGDVACDSYHKIAED 1435
Query: 220 IEMAEQLGLDFYRFSISWPRLLPKGFRTRISADGRQYYDNLINGLLDRGIEPMVTLYHSD 399
+ + LG+ YRFSISW R+LP G I+ G YY LI+ LL I+P VT+YH D
Sbjct: 1436 LVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLAASIQPQVTIYHWD 1495
Query: 400 MPKIFQDLGGWANPEMAEWFADYADVAFSLYGDRVKLWITINEP 531
+P+ QD+GGW N + + F +YADV F GD+VK WIT+NEP
Sbjct: 1496 LPQTLQDVGGWENETIVQRFKEYADVLFQRLGDKVKFWITLNEP 1539
Score = 144 bits (350), Expect = 2e-34
Identities = 68/164 (41%), Positives = 95/164 (57%)
Frame = +1
Query: 40 FPRWFKFGAATSSYQIEGSWNVSDKTPSTWDDYTHTQPHRIKDHSNGDVACDSYNQYEKD 219
FP F +GA+T ++ +EG W + S WD + + + +VA DSY++ D
Sbjct: 382 FPEGFLWGASTGAFNVEGGWAEGGRGVSIWDP--RRPLNTTEGQATLEVASDSYHKVASD 439
Query: 220 IEMAEQLGLDFYRFSISWPRLLPKGFRTRISADGRQYYDNLINGLLDRGIEPMVTLYHSD 399
+ + L Y+FSISW R+ P G + S G YY+ LI+ L D GIEPM TL+H D
Sbjct: 440 VALLCGLRAQVYKFSISWSRIFPMGHGSSPSLPGVAYYNKLIDRLQDAGIEPMATLFHWD 499
Query: 400 MPKIFQDLGGWANPEMAEWFADYADVAFSLYGDRVKLWITINEP 531
+P+ QD GGW N + + F DYA FS +GDRVKLW+T +EP
Sbjct: 500 LPQALQDHGGWQNESVVDAFLDYAAFCFSTFGDRVKLWVTFHEP 543
Score = 54.4 bits (125), Expect = 4e-07
Identities = 30/92 (32%), Positives = 43/92 (46%)
Frame = +1
Query: 253 YRFSISWPRLLPKGFRTRISADGRQYYDNLINGLLDRGIEPMVTLYHSDMPKIFQDLGGW 432
Y+ +SW +LLP G Q Y L+ L ++PMV L+H +P
Sbjct: 87 YKVFLSWAQLLPAGSTQNPDEKTVQCYRRLLKALKTARLQPMVILHHQTLPASTLR---- 142
Query: 433 ANPEMAEWFADYADVAFSLYGDRVKLWITINE 528
A+ FADYA AF +GD V +W T ++
Sbjct: 143 RTEAFADLFADYATFAFHSFGDLVGIWFTFSD 174
>AY191611-1|AAP12677.1| 1003|Homo sapiens lactase-phlorizin
hydrolase-1 protein.
Length = 1003
Score = 199 bits (485), Expect = 9e-51
Identities = 88/192 (45%), Positives = 123/192 (64%), Gaps = 4/192 (2%)
Frame = +1
Query: 52 FKFGAATSSYQIEGSWNVSDKTPSTWDDYTHTQPHRIKDHSNGDVACDSYNQYEKDIEMA 231
F +G ++S+YQIEG+W+ K PS WD++THT +KD++ GD+ACDSY+Q + D+ M
Sbjct: 339 FLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYHQLDADLNML 398
Query: 232 EQLGLDFYRFSISWPRLLPKGFRTRISADGRQYYDNLINGLLDRGIEPMVTLYHSDMPKI 411
L + YRFSISW R+ P G + I++ G YY+ LINGL+ I PMVTL+H D+P+
Sbjct: 399 RALKVKAYRFSISWSRIFPTGRNSSINSHGVDYYNRLINGLVASNIFPMVTLFHWDLPQA 458
Query: 412 FQDLGGWANPEMAEWFADYADVAFSLYGDRVKLWITINEPLHAC----DSSSRVLGVVEP 579
QD+GGW NP + + F YAD F +GDRVK W+T NEP++ S GV +P
Sbjct: 459 LQDIGGWENPALIDLFDSYADFCFQTFGDRVKFWMTFNEPMYLAWLGYGSGEFPPGVKDP 518
Query: 580 FLAPYLCTKTLL 615
APY T++
Sbjct: 519 GWAPYRIAHTVI 530
Score = 177 bits (431), Expect = 3e-44
Identities = 79/164 (48%), Positives = 109/164 (66%)
Frame = +1
Query: 40 FPRWFKFGAATSSYQIEGSWNVSDKTPSTWDDYTHTQPHRIKDHSNGDVACDSYNQYEKD 219
FP F + AA+++YQIEG+W K S WD ++HT P R+++ + GDVACDSY++ +D
Sbjct: 809 FPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSHT-PLRVENDAIGDVACDSYHKIAED 867
Query: 220 IEMAEQLGLDFYRFSISWPRLLPKGFRTRISADGRQYYDNLINGLLDRGIEPMVTLYHSD 399
+ + LG+ YRFSISW R+LP G I+ G YY LI+ LL I+P VT+YH D
Sbjct: 868 LVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLAASIQPQVTIYHWD 927
Query: 400 MPKIFQDLGGWANPEMAEWFADYADVAFSLYGDRVKLWITINEP 531
+P+ QD+GGW N + + F +YADV F GD+VK WIT+NEP
Sbjct: 928 LPQTLQDVGGWENETIVQRFKEYADVLFQRLGDKVKFWITLNEP 971
>M61850-1|AAA59504.1| 1927|Homo sapiens lactase phlorizinhydrolase
protein.
Length = 1927
Score = 197 bits (481), Expect = 3e-50
Identities = 87/185 (47%), Positives = 120/185 (64%), Gaps = 4/185 (2%)
Frame = +1
Query: 52 FKFGAATSSYQIEGSWNVSDKTPSTWDDYTHTQPHRIKDHSNGDVACDSYNQYEKDIEMA 231
F +G ++S+YQIEG+W+ K PS WD++THT +KD++ GD+ACDSY+Q + D+ M
Sbjct: 907 FLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYHQLDADLNML 966
Query: 232 EQLGLDFYRFSISWPRLLPKGFRTRISADGRQYYDNLINGLLDRGIEPMVTLYHSDMPKI 411
L + YRFSISW R+ P G + I++ G YY+ LINGL+ I PMVTL+H D+P+
Sbjct: 967 RALKVKAYRFSISWSRIFPTGRNSSINSHGVDYYNRLINGLVASNIFPMVTLFHWDLPQA 1026
Query: 412 FQDLGGWANPEMAEWFADYADVAFSLYGDRVKLWITINEPLHAC----DSSSRVLGVVEP 579
QD+GGW NP + + F YAD F +GDRVK W+T NEP++ S GV +P
Sbjct: 1027 LQDIGGWENPALIDLFDSYADFCFQTFGDRVKFWMTFNEPMYLAWLGYGSGEFPPGVKDP 1086
Query: 580 FLAPY 594
APY
Sbjct: 1087 GWAPY 1091
Score = 177 bits (431), Expect = 3e-44
Identities = 79/164 (48%), Positives = 109/164 (66%)
Frame = +1
Query: 40 FPRWFKFGAATSSYQIEGSWNVSDKTPSTWDDYTHTQPHRIKDHSNGDVACDSYNQYEKD 219
FP F + AA+++YQIEG+W K S WD ++HT P R+++ + GDVACDSY++ +D
Sbjct: 1377 FPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSHT-PLRVENDAIGDVACDSYHKIAED 1435
Query: 220 IEMAEQLGLDFYRFSISWPRLLPKGFRTRISADGRQYYDNLINGLLDRGIEPMVTLYHSD 399
+ + LG+ YRFSISW R+LP G I+ G YY LI+ LL I+P VT+YH D
Sbjct: 1436 LVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLAASIQPQVTIYHWD 1495
Query: 400 MPKIFQDLGGWANPEMAEWFADYADVAFSLYGDRVKLWITINEP 531
+P+ QD+GGW N + + F +YADV F GD+VK WIT+NEP
Sbjct: 1496 LPQTLQDVGGWENETIVQRFKEYADVLFQRLGDKVKFWITLNEP 1539
Score = 144 bits (350), Expect = 2e-34
Identities = 68/164 (41%), Positives = 95/164 (57%)
Frame = +1
Query: 40 FPRWFKFGAATSSYQIEGSWNVSDKTPSTWDDYTHTQPHRIKDHSNGDVACDSYNQYEKD 219
FP F +GA+T ++ +EG W + S WD + + + +VA DSY++ D
Sbjct: 382 FPEGFLWGASTGAFNVEGGWAEGGRGVSIWDP--RRPLNTTEGQATLEVASDSYHKVASD 439
Query: 220 IEMAEQLGLDFYRFSISWPRLLPKGFRTRISADGRQYYDNLINGLLDRGIEPMVTLYHSD 399
+ + L Y+FSISW R+ P G + S G YY+ LI+ L D GIEPM TL+H D
Sbjct: 440 VALLCGLRAQVYKFSISWSRIFPMGHGSSPSLPGVAYYNKLIDRLQDAGIEPMATLFHWD 499
Query: 400 MPKIFQDLGGWANPEMAEWFADYADVAFSLYGDRVKLWITINEP 531
+P+ QD GGW N + + F DYA FS +GDRVKLW+T +EP
Sbjct: 500 LPQALQDHGGWQNESVVDAFLDYAAFCFSTFGDRVKLWVTFHEP 543
Score = 54.4 bits (125), Expect = 4e-07
Identities = 30/92 (32%), Positives = 43/92 (46%)
Frame = +1
Query: 253 YRFSISWPRLLPKGFRTRISADGRQYYDNLINGLLDRGIEPMVTLYHSDMPKIFQDLGGW 432
Y+ +SW +LLP G Q Y L+ L ++PMV L+H +P
Sbjct: 87 YKVFLSWAQLLPAGSTQNPDEKTVQCYRRLLKALKTARLQPMVILHHQTLPASTLR---- 142
Query: 433 ANPEMAEWFADYADVAFSLYGDRVKLWITINE 528
A+ FADYA AF +GD V +W T ++
Sbjct: 143 RTEAFADLFADYATFAFHSFGDLVGIWFTFSD 174
>AC011893-3|AAX88924.1| 1927|Homo sapiens unknown protein.
Length = 1927
Score = 197 bits (481), Expect = 3e-50
Identities = 87/185 (47%), Positives = 120/185 (64%), Gaps = 4/185 (2%)
Frame = +1
Query: 52 FKFGAATSSYQIEGSWNVSDKTPSTWDDYTHTQPHRIKDHSNGDVACDSYNQYEKDIEMA 231
F +G ++S+YQIEG+W+ K PS WD++THT +KD++ GD+ACDSY+Q + D+ M
Sbjct: 907 FLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYHQLDADLNML 966
Query: 232 EQLGLDFYRFSISWPRLLPKGFRTRISADGRQYYDNLINGLLDRGIEPMVTLYHSDMPKI 411
L + YRFSISW R+ P G + I++ G YY+ LINGL+ I PMVTL+H D+P+
Sbjct: 967 RALKVKAYRFSISWSRIFPTGRNSSINSHGVDYYNRLINGLVASNIFPMVTLFHWDLPQA 1026
Query: 412 FQDLGGWANPEMAEWFADYADVAFSLYGDRVKLWITINEPLHAC----DSSSRVLGVVEP 579
QD+GGW NP + + F YAD F +GDRVK W+T NEP++ S GV +P
Sbjct: 1027 LQDIGGWENPALIDLFDSYADFCFQTFGDRVKFWMTFNEPMYLAWLGYGSGEFPPGVKDP 1086
Query: 580 FLAPY 594
APY
Sbjct: 1087 GWAPY 1091
Score = 177 bits (431), Expect = 3e-44
Identities = 79/164 (48%), Positives = 109/164 (66%)
Frame = +1
Query: 40 FPRWFKFGAATSSYQIEGSWNVSDKTPSTWDDYTHTQPHRIKDHSNGDVACDSYNQYEKD 219
FP F + AA+++YQIEG+W K S WD ++HT P R+++ + GDVACDSY++ +D
Sbjct: 1377 FPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSHT-PLRVENDAIGDVACDSYHKIAED 1435
Query: 220 IEMAEQLGLDFYRFSISWPRLLPKGFRTRISADGRQYYDNLINGLLDRGIEPMVTLYHSD 399
+ + LG+ YRFSISW R+LP G I+ G YY LI+ LL I+P VT+YH D
Sbjct: 1436 LVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLAASIQPQVTIYHWD 1495
Query: 400 MPKIFQDLGGWANPEMAEWFADYADVAFSLYGDRVKLWITINEP 531
+P+ QD+GGW N + + F +YADV F GD+VK WIT+NEP
Sbjct: 1496 LPQTLQDVGGWENETIVQRFKEYADVLFQRLGDKVKFWITLNEP 1539
Score = 144 bits (350), Expect = 2e-34
Identities = 68/164 (41%), Positives = 95/164 (57%)
Frame = +1
Query: 40 FPRWFKFGAATSSYQIEGSWNVSDKTPSTWDDYTHTQPHRIKDHSNGDVACDSYNQYEKD 219
FP F +GA+T ++ +EG W + S WD + + + +VA DSY++ D
Sbjct: 382 FPEGFLWGASTGAFNVEGGWAEGGRGVSIWDP--RRPLNTTEGQATLEVASDSYHKVASD 439
Query: 220 IEMAEQLGLDFYRFSISWPRLLPKGFRTRISADGRQYYDNLINGLLDRGIEPMVTLYHSD 399
+ + L Y+FSISW R+ P G + S G YY+ LI+ L D GIEPM TL+H D
Sbjct: 440 VALLCGLRAQVYKFSISWSRIFPMGHGSSPSLPGVAYYNKLIDRLQDAGIEPMATLFHWD 499
Query: 400 MPKIFQDLGGWANPEMAEWFADYADVAFSLYGDRVKLWITINEP 531
+P+ QD GGW N + + F DYA FS +GDRVKLW+T +EP
Sbjct: 500 LPQALQDHGGWQNESVVDAFLDYAAFCFSTFGDRVKLWVTFHEP 543
Score = 54.4 bits (125), Expect = 4e-07
Identities = 30/92 (32%), Positives = 43/92 (46%)
Frame = +1
Query: 253 YRFSISWPRLLPKGFRTRISADGRQYYDNLINGLLDRGIEPMVTLYHSDMPKIFQDLGGW 432
Y+ +SW +LLP G Q Y L+ L ++PMV L+H +P
Sbjct: 87 YKVFLSWAQLLPAGSTQNPDEKTVQCYRRLLKALKTARLQPMVILHHQTLPASTLR---- 142
Query: 433 ANPEMAEWFADYADVAFSLYGDRVKLWITINE 528
A+ FADYA AF +GD V +W T ++
Sbjct: 143 RTEAFADLFADYATFAFHSFGDLVGIWFTFSD 174
>BC101829-1|AAI01830.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 180 bits (437), Expect = 6e-45
Identities = 79/163 (48%), Positives = 105/163 (64%)
Frame = +1
Query: 40 FPRWFKFGAATSSYQIEGSWNVSDKTPSTWDDYTHTQPHRIKDHSNGDVACDSYNQYEKD 219
FP F + AAT++YQ+EG W+ K P WD +TH R+ + GDVAC SY +E+D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 220 IEMAEQLGLDFYRFSISWPRLLPKGFRTRISADGRQYYDNLINGLLDRGIEPMVTLYHSD 399
++ +QLGL YRFS+SW RLLP G I+ G YY+ +I+ LL G+ P+VTLYH D
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122
Query: 400 MPKIFQDLGGWANPEMAEWFADYADVAFSLYGDRVKLWITINE 528
+P+ +D GGW + + E F YA FS +GDRVK WITINE
Sbjct: 123 LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINE 165
>AK222963-1|BAD96683.1| 469|Homo sapiens cytosolic beta-glucosidase
variant protein.
Length = 469
Score = 180 bits (437), Expect = 6e-45
Identities = 79/163 (48%), Positives = 105/163 (64%)
Frame = +1
Query: 40 FPRWFKFGAATSSYQIEGSWNVSDKTPSTWDDYTHTQPHRIKDHSNGDVACDSYNQYEKD 219
FP F + AAT++YQ+EG W+ K P WD +TH R+ + GDVAC SY +E+D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 220 IEMAEQLGLDFYRFSISWPRLLPKGFRTRISADGRQYYDNLINGLLDRGIEPMVTLYHSD 399
++ +QLGL YRFS+SW RLLP G I+ G YY+ +I+ LL G+ P+VTLYH D
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122
Query: 400 MPKIFQDLGGWANPEMAEWFADYADVAFSLYGDRVKLWITINE 528
+P+ +D GGW + + E F YA FS +GDRVK WITINE
Sbjct: 123 LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINE 165
>AJ278964-1|CAC08178.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 180 bits (437), Expect = 6e-45
Identities = 79/163 (48%), Positives = 105/163 (64%)
Frame = +1
Query: 40 FPRWFKFGAATSSYQIEGSWNVSDKTPSTWDDYTHTQPHRIKDHSNGDVACDSYNQYEKD 219
FP F + AAT++YQ+EG W+ K P WD +TH R+ + GDVAC SY +E+D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 220 IEMAEQLGLDFYRFSISWPRLLPKGFRTRISADGRQYYDNLINGLLDRGIEPMVTLYHSD 399
++ +QLGL YRFS+SW RLLP G I+ G YY+ +I+ LL G+ P+VTLYH D
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122
Query: 400 MPKIFQDLGGWANPEMAEWFADYADVAFSLYGDRVKLWITINE 528
+P+ +D GGW + + E F YA FS +GDRVK WITINE
Sbjct: 123 LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINE 165
>AF323990-1|AAL37305.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 180 bits (437), Expect = 6e-45
Identities = 79/163 (48%), Positives = 105/163 (64%)
Frame = +1
Query: 40 FPRWFKFGAATSSYQIEGSWNVSDKTPSTWDDYTHTQPHRIKDHSNGDVACDSYNQYEKD 219
FP F + AAT++YQ+EG W+ K P WD +TH R+ + GDVAC SY +E+D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 220 IEMAEQLGLDFYRFSISWPRLLPKGFRTRISADGRQYYDNLINGLLDRGIEPMVTLYHSD 399
++ +QLGL YRFS+SW RLLP G I+ G YY+ +I+ LL G+ P+VTLYH D
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122
Query: 400 MPKIFQDLGGWANPEMAEWFADYADVAFSLYGDRVKLWITINE 528
+P+ +D GGW + + E F YA FS +GDRVK WITINE
Sbjct: 123 LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINE 165
>AB017913-1|BAB18741.1| 469|Homo sapiens cytosolic
beta-glucosidase-like protein-1 protein.
Length = 469
Score = 180 bits (437), Expect = 6e-45
Identities = 79/163 (48%), Positives = 105/163 (64%)
Frame = +1
Query: 40 FPRWFKFGAATSSYQIEGSWNVSDKTPSTWDDYTHTQPHRIKDHSNGDVACDSYNQYEKD 219
FP F + AAT++YQ+EG W+ K P WD +TH R+ + GDVAC SY +E+D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 220 IEMAEQLGLDFYRFSISWPRLLPKGFRTRISADGRQYYDNLINGLLDRGIEPMVTLYHSD 399
++ +QLGL YRFS+SW RLLP G I+ G YY+ +I+ LL G+ P+VTLYH D
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122
Query: 400 MPKIFQDLGGWANPEMAEWFADYADVAFSLYGDRVKLWITINE 528
+P+ +D GGW + + E F YA FS +GDRVK WITINE
Sbjct: 123 LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINE 165
>AF317840-1|AAG39217.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 179 bits (435), Expect = 1e-44
Identities = 79/163 (48%), Positives = 105/163 (64%)
Frame = +1
Query: 40 FPRWFKFGAATSSYQIEGSWNVSDKTPSTWDDYTHTQPHRIKDHSNGDVACDSYNQYEKD 219
FP F + AAT++YQ+EG W+ K P WD +TH R+ + GDVAC SY +E+D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 220 IEMAEQLGLDFYRFSISWPRLLPKGFRTRISADGRQYYDNLINGLLDRGIEPMVTLYHSD 399
++ +QLGL YRFS+SW RLLP G I+ G YY+ +I+ LL G+ P+VTLYH D
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122
Query: 400 MPKIFQDLGGWANPEMAEWFADYADVAFSLYGDRVKLWITINE 528
+P+ +D GGW + + E F YA FS +GDRVK WITINE
Sbjct: 123 LPQTLEDQGGWWSEAIIESFDKYAQFCFSTFGDRVKQWITINE 165
>AY358729-1|AAQ89091.1| 567|Homo sapiens KPVW3022 protein.
Length = 567
Score = 171 bits (415), Expect = 3e-42
Identities = 74/166 (44%), Positives = 110/166 (66%), Gaps = 2/166 (1%)
Frame = +1
Query: 40 FPRWFKFGAATSSYQIEGSWNVSDKTPSTWDDYTHTQPHRIKDHSNGDVACDSYNQYEKD 219
FP F +G +S+YQ EG+W+ K PS WD +TH+ ++ + DVACD Y + ++D
Sbjct: 37 FPLGFSWGVGSSAYQTEGAWDQDGKGPSIWDVFTHSGKGKVLGNETADVACDGYYKVQED 96
Query: 220 IEMAEQLGLDFYRFSISWPRLLPKGFRT-RISADGRQYYDNLINGLLDRGIEPMVTLYHS 396
I + +L ++ YRFS+SWPRLLP G R +++ G ++Y +LI+ LL I P+VTL+H
Sbjct: 97 IILLRELHVNHYRFSLSWPRLLPTGIRAEQVNKKGIEFYSDLIDALLSSNITPIVTLHHW 156
Query: 397 DMPKIFQ-DLGGWANPEMAEWFADYADVAFSLYGDRVKLWITINEP 531
D+P++ Q GGW N MA +F DYA++ F +GDRVK WIT ++P
Sbjct: 157 DLPQLLQVKYGGWQNVSMANYFRDYANLCFEAFGDRVKHWITFSDP 202
>BC113653-1|AAI13654.1| 1044|Homo sapiens klotho beta protein.
Length = 1044
Score = 163 bits (395), Expect = 7e-40
Identities = 77/165 (46%), Positives = 104/165 (63%), Gaps = 1/165 (0%)
Frame = +1
Query: 40 FPRWFKFGAATSSYQIEGSWNVSDKTPSTWDDYTHTQPHRIKDHSNGDVACDSYNQYEKD 219
FP+ F +G T + Q+EGSW K PS WD + HT +K+ S+ + + DSY EKD
Sbjct: 81 FPKNFFWGIGTGALQVEGSWKKDGKGPSIWDHFIHTH---LKNVSSTNGSSDSYIFLEKD 137
Query: 220 IEMAEQLGLDFYRFSISWPRLLPKGFRTRISADGRQYYDNLINGLLDRGIEPMVTLYHSD 399
+ + +G+ FY+FSISWPRL P G T +A G QYY L++ L+ R IEP+VTLYH D
Sbjct: 138 LSALDFIGVSFYQFSISWPRLFPDGIVTVANAKGLQYYSTLLDALVLRNIEPIVTLYHWD 197
Query: 400 MPKIFQD-LGGWANPEMAEWFADYADVAFSLYGDRVKLWITINEP 531
+P Q+ GGW N + + F DYA F ++GDRVK WITI+ P
Sbjct: 198 LPLALQEKYGGWKNDTIIDIFNDYATYCFQMFGDRVKYWITIHNP 242
Score = 93.1 bits (221), Expect = 9e-19
Identities = 59/183 (32%), Positives = 85/183 (46%), Gaps = 10/183 (5%)
Frame = +1
Query: 40 FPRWFKFGAATSSYQIEG---SWNVSDKTPSTWDDYTHTQPHRIKDH--SNGDVACDSYN 204
FP F +G S + E S SD W+ + HR++ C +
Sbjct: 521 FPCDFSWGVTESVLKPESVASSPQFSDPHLYVWNATGNRLLHRVEGVRLKTRPAQCTDFV 580
Query: 205 QYEKDIEMAEQLGLDFYRFSISWPRLLPKGFRTRISADGRQYYDNLINGLLDRGIEPMVT 384
+K +EM ++ + YRF++ W +LP G + ++ +YY +++ L GI MVT
Sbjct: 581 NIKKQLEMLARMKVTHYRFALDWASVLPTGNLSAVNRQALRYYRCVVSEGLKLGISAMVT 640
Query: 385 LY-----HSDMPKIFQDLGGWANPEMAEWFADYADVAFSLYGDRVKLWITINEPLHACDS 549
LY H +P+ GW NP AE F YA + F GD VKLWITINEP D
Sbjct: 641 LYYPTHAHLGLPEPLLHADGWLNPSTAEAFQAYAGLCFQELGDLVKLWITINEPNRLSDI 700
Query: 550 SSR 558
+R
Sbjct: 701 YNR 703
>BC104871-1|AAI04872.1| 1044|Homo sapiens klotho beta protein.
Length = 1044
Score = 163 bits (395), Expect = 7e-40
Identities = 77/165 (46%), Positives = 104/165 (63%), Gaps = 1/165 (0%)
Frame = +1
Query: 40 FPRWFKFGAATSSYQIEGSWNVSDKTPSTWDDYTHTQPHRIKDHSNGDVACDSYNQYEKD 219
FP+ F +G T + Q+EGSW K PS WD + HT +K+ S+ + + DSY EKD
Sbjct: 81 FPKNFFWGIGTGALQVEGSWKKDGKGPSIWDHFIHTH---LKNVSSTNGSSDSYIFLEKD 137
Query: 220 IEMAEQLGLDFYRFSISWPRLLPKGFRTRISADGRQYYDNLINGLLDRGIEPMVTLYHSD 399
+ + +G+ FY+FSISWPRL P G T +A G QYY L++ L+ R IEP+VTLYH D
Sbjct: 138 LSALDFIGVSFYQFSISWPRLFPDGIVTVANAKGLQYYSTLLDALVLRNIEPIVTLYHWD 197
Query: 400 MPKIFQD-LGGWANPEMAEWFADYADVAFSLYGDRVKLWITINEP 531
+P Q+ GGW N + + F DYA F ++GDRVK WITI+ P
Sbjct: 198 LPLALQEKYGGWKNDTIIDIFNDYATYCFQMFGDRVKYWITIHNP 242
Score = 93.1 bits (221), Expect = 9e-19
Identities = 59/183 (32%), Positives = 85/183 (46%), Gaps = 10/183 (5%)
Frame = +1
Query: 40 FPRWFKFGAATSSYQIEG---SWNVSDKTPSTWDDYTHTQPHRIKDH--SNGDVACDSYN 204
FP F +G S + E S SD W+ + HR++ C +
Sbjct: 521 FPCDFSWGVTESVLKPESVASSPQFSDPHLYVWNATGNRLLHRVEGVRLKTRPAQCTDFV 580
Query: 205 QYEKDIEMAEQLGLDFYRFSISWPRLLPKGFRTRISADGRQYYDNLINGLLDRGIEPMVT 384
+K +EM ++ + YRF++ W +LP G + ++ +YY +++ L GI MVT
Sbjct: 581 NIKKQLEMLARMKVTHYRFALDWASVLPTGNLSAVNRQALRYYRCVVSEGLKLGISAMVT 640
Query: 385 LY-----HSDMPKIFQDLGGWANPEMAEWFADYADVAFSLYGDRVKLWITINEPLHACDS 549
LY H +P+ GW NP AE F YA + F GD VKLWITINEP D
Sbjct: 641 LYYPTHAHLGLPEPLLHADGWLNPSTAEAFQAYAGLCFQELGDLVKLWITINEPNRLSDI 700
Query: 550 SSR 558
+R
Sbjct: 701 YNR 703
>AB079373-1|BAC56857.1| 1044|Homo sapiens klotho beta like protein
protein.
Length = 1044
Score = 163 bits (395), Expect = 7e-40
Identities = 77/165 (46%), Positives = 104/165 (63%), Gaps = 1/165 (0%)
Frame = +1
Query: 40 FPRWFKFGAATSSYQIEGSWNVSDKTPSTWDDYTHTQPHRIKDHSNGDVACDSYNQYEKD 219
FP+ F +G T + Q+EGSW K PS WD + HT +K+ S+ + + DSY EKD
Sbjct: 81 FPKNFFWGIGTGALQVEGSWKKDGKGPSIWDHFIHTH---LKNVSSTNGSSDSYIFLEKD 137
Query: 220 IEMAEQLGLDFYRFSISWPRLLPKGFRTRISADGRQYYDNLINGLLDRGIEPMVTLYHSD 399
+ + +G+ FY+FSISWPRL P G T +A G QYY L++ L+ R IEP+VTLYH D
Sbjct: 138 LSALDFIGVSFYQFSISWPRLFPDGIVTVANAKGLQYYSTLLDALVLRNIEPIVTLYHWD 197
Query: 400 MPKIFQD-LGGWANPEMAEWFADYADVAFSLYGDRVKLWITINEP 531
+P Q+ GGW N + + F DYA F ++GDRVK WITI+ P
Sbjct: 198 LPLALQEKYGGWKNDTIIDIFNDYATYCFQMFGDRVKYWITIHNP 242
Score = 93.1 bits (221), Expect = 9e-19
Identities = 59/183 (32%), Positives = 85/183 (46%), Gaps = 10/183 (5%)
Frame = +1
Query: 40 FPRWFKFGAATSSYQIEG---SWNVSDKTPSTWDDYTHTQPHRIKDH--SNGDVACDSYN 204
FP F +G S + E S SD W+ + HR++ C +
Sbjct: 521 FPCDFSWGVTESVLKPESVASSPQFSDPHLYVWNATGNRLLHRVEGVRLKTRPAQCTDFV 580
Query: 205 QYEKDIEMAEQLGLDFYRFSISWPRLLPKGFRTRISADGRQYYDNLINGLLDRGIEPMVT 384
+K +EM ++ + YRF++ W +LP G + ++ +YY +++ L GI MVT
Sbjct: 581 NIKKQLEMLARMKVTHYRFALDWASVLPTGNLSAVNRQALRYYRCVVSEGLKLGISAMVT 640
Query: 385 LY-----HSDMPKIFQDLGGWANPEMAEWFADYADVAFSLYGDRVKLWITINEPLHACDS 549
LY H +P+ GW NP AE F YA + F GD VKLWITINEP D
Sbjct: 641 LYYPTHAHLGLPEPLLHADGWLNPSTAEAFQAYAGLCFQELGDLVKLWITINEPNRLSDI 700
Query: 550 SSR 558
+R
Sbjct: 701 YNR 703
>Z92540-2|CAC94767.1| 273|Homo sapiens 179I15.1 (klotho) protein.
Length = 273
Score = 142 bits (344), Expect = 1e-33
Identities = 74/180 (41%), Positives = 102/180 (56%), Gaps = 16/180 (8%)
Frame = +1
Query: 40 FPRWFKFGAATSSYQIEGSWNVSDKTPSTWDDYTH---TQPHRIKDHS------------ 174
FP F + +++YQ EG W K S WD +TH P ++ S
Sbjct: 61 FPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPLQPA 120
Query: 175 NGDVACDSYNQYEKDIEMAEQLGLDFYRFSISWPRLLPKGFRTRISADGRQYYDNLINGL 354
GDVA DSYN +D E +LG+ YRFSISW R+LP G + +G +YY L+ L
Sbjct: 121 TGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLERL 180
Query: 355 LDRGIEPMVTLYHSDMPKIFQD-LGGWANPEMAEWFADYADVAFSLYGDRVKLWITINEP 531
+ G++P+VTLYH D+P+ QD GGWAN +A+ F DYA++ F +G +VK WITI+ P
Sbjct: 181 RELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITIDNP 240
>AL161898-1|CAH71888.1| 1012|Homo sapiens klotho protein.
Length = 1012
Score = 142 bits (344), Expect = 1e-33
Identities = 74/180 (41%), Positives = 102/180 (56%), Gaps = 16/180 (8%)
Frame = +1
Query: 40 FPRWFKFGAATSSYQIEGSWNVSDKTPSTWDDYTH---TQPHRIKDHS------------ 174
FP F + +++YQ EG W K S WD +TH P ++ S
Sbjct: 61 FPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPLQPA 120
Query: 175 NGDVACDSYNQYEKDIEMAEQLGLDFYRFSISWPRLLPKGFRTRISADGRQYYDNLINGL 354
GDVA DSYN +D E +LG+ YRFSISW R+LP G + +G +YY L+ L
Sbjct: 121 TGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLERL 180
Query: 355 LDRGIEPMVTLYHSDMPKIFQD-LGGWANPEMAEWFADYADVAFSLYGDRVKLWITINEP 531
+ G++P+VTLYH D+P+ QD GGWAN +A+ F DYA++ F +G +VK WITI+ P
Sbjct: 181 RELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITIDNP 240
Score = 78.6 bits (185), Expect = 2e-14
Identities = 50/183 (27%), Positives = 89/183 (48%), Gaps = 10/183 (5%)
Frame = +1
Query: 13 PLLANKELH--FPRWFKFGAATSSYQIEGSWN-VSDKTPSTWDDYTHTQPHRIKD--HSN 177
PL N+ L FP F +G + Q++ + + +D WD + + ++
Sbjct: 508 PLPENQPLEGTFPCDFAWGVVDNYIQVDTTLSQFTDLNVYLWDVHHSKRLIKVDGVVTKK 567
Query: 178 GDVACDSYNQYEKDIEMAEQLGLDFYRFSISWPRLLPKGFRTRISADGRQYYDNLINGLL 357
C + + I + +++ + +RFS+ W +LP G +++++ QYY + + L+
Sbjct: 568 RKSYCVDFAAIQPQIALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELV 627
Query: 358 DRGIEPMVTLY-----HSDMPKIFQDLGGWANPEMAEWFADYADVAFSLYGDRVKLWITI 522
I P+V L+ + +P++ G W NP A FA+YA + F G VKLWIT+
Sbjct: 628 RVNITPVVALWQPMAPNQGLPRLLARQGAWENPYTALAFAEYARLCFQELGHHVKLWITM 687
Query: 523 NEP 531
NEP
Sbjct: 688 NEP 690
>AB009667-2|BAA24941.1| 549|Homo sapiens Klotho protein (KL)
protein.
Length = 549
Score = 142 bits (344), Expect = 1e-33
Identities = 74/180 (41%), Positives = 102/180 (56%), Gaps = 16/180 (8%)
Frame = +1
Query: 40 FPRWFKFGAATSSYQIEGSWNVSDKTPSTWDDYTH---TQPHRIKDHS------------ 174
FP F + +++YQ EG W K S WD +TH P ++ S
Sbjct: 61 FPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPLQPA 120
Query: 175 NGDVACDSYNQYEKDIEMAEQLGLDFYRFSISWPRLLPKGFRTRISADGRQYYDNLINGL 354
GDVA DSYN +D E +LG+ YRFSISW R+LP G + +G +YY L+ L
Sbjct: 121 TGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLERL 180
Query: 355 LDRGIEPMVTLYHSDMPKIFQD-LGGWANPEMAEWFADYADVAFSLYGDRVKLWITINEP 531
+ G++P+VTLYH D+P+ QD GGWAN +A+ F DYA++ F +G +VK WITI+ P
Sbjct: 181 RELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITIDNP 240
>AB009667-1|BAA24940.1| 1012|Homo sapiens Klotho protein (KL)
protein.
Length = 1012
Score = 142 bits (344), Expect = 1e-33
Identities = 74/180 (41%), Positives = 102/180 (56%), Gaps = 16/180 (8%)
Frame = +1
Query: 40 FPRWFKFGAATSSYQIEGSWNVSDKTPSTWDDYTH---TQPHRIKDHS------------ 174
FP F + +++YQ EG W K S WD +TH P ++ S
Sbjct: 61 FPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPLQPA 120
Query: 175 NGDVACDSYNQYEKDIEMAEQLGLDFYRFSISWPRLLPKGFRTRISADGRQYYDNLINGL 354
GDVA DSYN +D E +LG+ YRFSISW R+LP G + +G +YY L+ L
Sbjct: 121 TGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLERL 180
Query: 355 LDRGIEPMVTLYHSDMPKIFQD-LGGWANPEMAEWFADYADVAFSLYGDRVKLWITINEP 531
+ G++P+VTLYH D+P+ QD GGWAN +A+ F DYA++ F +G +VK WITI+ P
Sbjct: 181 RELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITIDNP 240
Score = 78.6 bits (185), Expect = 2e-14
Identities = 50/183 (27%), Positives = 89/183 (48%), Gaps = 10/183 (5%)
Frame = +1
Query: 13 PLLANKELH--FPRWFKFGAATSSYQIEGSWN-VSDKTPSTWDDYTHTQPHRIKD--HSN 177
PL N+ L FP F +G + Q++ + + +D WD + + ++
Sbjct: 508 PLPENQPLEGTFPCDFAWGVVDNYIQVDTTLSQFTDLNVYLWDVHHSKRLIKVDGVVTKK 567
Query: 178 GDVACDSYNQYEKDIEMAEQLGLDFYRFSISWPRLLPKGFRTRISADGRQYYDNLINGLL 357
C + + I + +++ + +RFS+ W +LP G +++++ QYY + + L+
Sbjct: 568 RKSYCVDFAAIQPQIALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELV 627
Query: 358 DRGIEPMVTLY-----HSDMPKIFQDLGGWANPEMAEWFADYADVAFSLYGDRVKLWITI 522
I P+V L+ + +P++ G W NP A FA+YA + F G VKLWIT+
Sbjct: 628 RVNITPVVALWQPMAPNQGLPRLLARQGAWENPYTALAFAEYARLCFQELGHHVKLWITM 687
Query: 523 NEP 531
NEP
Sbjct: 688 NEP 690
>AB005142-1|BAA23382.1| 1012|Homo sapiens klotho protein.
Length = 1012
Score = 142 bits (344), Expect = 1e-33
Identities = 74/180 (41%), Positives = 102/180 (56%), Gaps = 16/180 (8%)
Frame = +1
Query: 40 FPRWFKFGAATSSYQIEGSWNVSDKTPSTWDDYTH---TQPHRIKDHS------------ 174
FP F + +++YQ EG W K S WD +TH P ++ S
Sbjct: 61 FPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPLQPA 120
Query: 175 NGDVACDSYNQYEKDIEMAEQLGLDFYRFSISWPRLLPKGFRTRISADGRQYYDNLINGL 354
GDVA DSYN +D E +LG+ YRFSISW R+LP G + +G +YY L+ L
Sbjct: 121 TGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLERL 180
Query: 355 LDRGIEPMVTLYHSDMPKIFQD-LGGWANPEMAEWFADYADVAFSLYGDRVKLWITINEP 531
+ G++P+VTLYH D+P+ QD GGWAN +A+ F DYA++ F +G +VK WITI+ P
Sbjct: 181 RELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITIDNP 240
Score = 78.6 bits (185), Expect = 2e-14
Identities = 50/183 (27%), Positives = 89/183 (48%), Gaps = 10/183 (5%)
Frame = +1
Query: 13 PLLANKELH--FPRWFKFGAATSSYQIEGSWN-VSDKTPSTWDDYTHTQPHRIKD--HSN 177
PL N+ L FP F +G + Q++ + + +D WD + + ++
Sbjct: 508 PLPENQPLEGTFPCDFAWGVVDNYIQVDTTLSQFTDLNVYLWDVHHSKRLIKVDGVVTKK 567
Query: 178 GDVACDSYNQYEKDIEMAEQLGLDFYRFSISWPRLLPKGFRTRISADGRQYYDNLINGLL 357
C + + I + +++ + +RFS+ W +LP G +++++ QYY + + L+
Sbjct: 568 RKSYCVDFAAIQPQIALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELV 627
Query: 358 DRGIEPMVTLY-----HSDMPKIFQDLGGWANPEMAEWFADYADVAFSLYGDRVKLWITI 522
I P+V L+ + +P++ G W NP A FA+YA + F G VKLWIT+
Sbjct: 628 RVNITPVVALWQPMAPNQGLPRLLARQGAWENPYTALAFAEYARLCFQELGHHVKLWITM 687
Query: 523 NEP 531
NEP
Sbjct: 688 NEP 690
>BC109377-1|AAI09378.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 101 bits (241), Expect = 3e-21
Identities = 42/85 (49%), Positives = 56/85 (65%)
Frame = +1
Query: 40 FPRWFKFGAATSSYQIEGSWNVSDKTPSTWDDYTHTQPHRIKDHSNGDVACDSYNQYEKD 219
FP F + AAT++YQ+EG W+ K P WD +TH R+ + GDVAC SY +E+D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 220 IEMAEQLGLDFYRFSISWPRLLPKG 294
++ +QLGL YRFS+SW RLLP G
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDG 87
>BC029362-1|AAH29362.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 101 bits (241), Expect = 3e-21
Identities = 42/85 (49%), Positives = 56/85 (65%)
Frame = +1
Query: 40 FPRWFKFGAATSSYQIEGSWNVSDKTPSTWDDYTHTQPHRIKDHSNGDVACDSYNQYEKD 219
FP F + AAT++YQ+EG W+ K P WD +TH R+ + GDVAC SY +E+D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 220 IEMAEQLGLDFYRFSISWPRLLPKG 294
++ +QLGL YRFS+SW RLLP G
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDG 87
>BC070188-1|AAH70188.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 97.1 bits (231), Expect = 5e-20
Identities = 41/85 (48%), Positives = 55/85 (64%)
Frame = +1
Query: 40 FPRWFKFGAATSSYQIEGSWNVSDKTPSTWDDYTHTQPHRIKDHSNGDVACDSYNQYEKD 219
FP F + AAT++YQ+EG W+ K WD +TH R+ + GDVAC SY +E+D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGLCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 220 IEMAEQLGLDFYRFSISWPRLLPKG 294
++ +QLGL YRFS+SW RLLP G
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDG 87
>Z84483-1|CAC94773.1| 739|Homo sapiens 46H23.1 (Klotho) protein.
Length = 739
Score = 78.6 bits (185), Expect = 2e-14
Identities = 50/183 (27%), Positives = 89/183 (48%), Gaps = 10/183 (5%)
Frame = +1
Query: 13 PLLANKELH--FPRWFKFGAATSSYQIEGSWN-VSDKTPSTWDDYTHTQPHRIKD--HSN 177
PL N+ L FP F +G + Q++ + + +D WD + + ++
Sbjct: 235 PLPENQPLEGTFPCDFAWGVVDNYIQVDTTLSQFTDLNVYLWDVHHSKRLIKVDGVVTKK 294
Query: 178 GDVACDSYNQYEKDIEMAEQLGLDFYRFSISWPRLLPKGFRTRISADGRQYYDNLINGLL 357
C + + I + +++ + +RFS+ W +LP G +++++ QYY + + L+
Sbjct: 295 RKSYCVDFAAIQPQIALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELV 354
Query: 358 DRGIEPMVTLY-----HSDMPKIFQDLGGWANPEMAEWFADYADVAFSLYGDRVKLWITI 522
I P+V L+ + +P++ G W NP A FA+YA + F G VKLWIT+
Sbjct: 355 RVNITPVVALWQPMAPNQGLPRLLARQGAWENPYTALAFAEYARLCFQELGHHVKLWITM 414
Query: 523 NEP 531
NEP
Sbjct: 415 NEP 417
>BC111769-1|AAI11770.1| 177|Homo sapiens FLJ40448 protein protein.
Length = 177
Score = 34.3 bits (75), Expect = 0.42
Identities = 12/25 (48%), Positives = 15/25 (60%)
Frame = +2
Query: 551 AHAFLGSSSHSWLHICARRLCSWLT 625
AH G + WLH+C+RR C LT
Sbjct: 81 AHPVAGGTQEPWLHLCSRRTCGQLT 105
>AK097767-1|BAC05165.1| 185|Homo sapiens protein ( Homo sapiens
cDNA FLJ40448 fis, clone TESTI2040815. ).
Length = 185
Score = 34.3 bits (75), Expect = 0.42
Identities = 12/25 (48%), Positives = 15/25 (60%)
Frame = +2
Query: 551 AHAFLGSSSHSWLHICARRLCSWLT 625
AH G + WLH+C+RR C LT
Sbjct: 81 AHPVAGGTQEPWLHLCSRRTCGQLT 105
>U94777-1|AAC52081.1| 842|Homo sapiens muscle glycogen
phosphorylase protein.
Length = 842
Score = 33.1 bits (72), Expect = 0.98
Identities = 17/51 (33%), Positives = 24/51 (47%)
Frame = +1
Query: 103 VSDKTPSTWDDYTHTQPHRIKDHSNGDVACDSYNQYEKDIEMAEQLGLDFY 255
V D+ +T DY H ++DH G + YEKD + L L+FY
Sbjct: 41 VKDRNVATPRDYYFALAHTVRDHLVGRWIRTQQHYYEKDPKRIYYLSLEFY 91
>M32598-1|AAA60231.1| 842|Homo sapiens PYGM protein.
Length = 842
Score = 33.1 bits (72), Expect = 0.98
Identities = 17/51 (33%), Positives = 24/51 (47%)
Frame = +1
Query: 103 VSDKTPSTWDDYTHTQPHRIKDHSNGDVACDSYNQYEKDIEMAEQLGLDFY 255
V D+ +T DY H ++DH G + YEKD + L L+FY
Sbjct: 41 VKDRNVATPRDYYFALAHTVRDHLVGRWIRTQQHYYEKDPKRIYYLSLEFY 91
>BC130514-1|AAI30515.1| 842|Homo sapiens phosphorylase, glycogen;
muscle (McArdle syndrome, glycogen storage disease typ
protein.
Length = 842
Score = 33.1 bits (72), Expect = 0.98
Identities = 17/51 (33%), Positives = 24/51 (47%)
Frame = +1
Query: 103 VSDKTPSTWDDYTHTQPHRIKDHSNGDVACDSYNQYEKDIEMAEQLGLDFY 255
V D+ +T DY H ++DH G + YEKD + L L+FY
Sbjct: 41 VKDRNVATPRDYYFALAHTVRDHLVGRWIRTQQHYYEKDPKRIYYLSLEFY 91
>BC126392-1|AAI26393.1| 842|Homo sapiens phosphorylase, glycogen;
muscle (McArdle syndrome, glycogen storage disease typ
protein.
Length = 842
Score = 33.1 bits (72), Expect = 0.98
Identities = 17/51 (33%), Positives = 24/51 (47%)
Frame = +1
Query: 103 VSDKTPSTWDDYTHTQPHRIKDHSNGDVACDSYNQYEKDIEMAEQLGLDFY 255
V D+ +T DY H ++DH G + YEKD + L L+FY
Sbjct: 41 VKDRNVATPRDYYFALAHTVRDHLVGRWIRTQQHYYEKDPKRIYYLSLEFY 91
>AF066859-1|AAC17451.1| 842|Homo sapiens muscle glycogen
phosphorylase protein.
Length = 842
Score = 33.1 bits (72), Expect = 0.98
Identities = 17/51 (33%), Positives = 24/51 (47%)
Frame = +1
Query: 103 VSDKTPSTWDDYTHTQPHRIKDHSNGDVACDSYNQYEKDIEMAEQLGLDFY 255
V D+ +T DY H ++DH G + YEKD + L L+FY
Sbjct: 41 VKDRNVATPRDYYFALAHTVRDHLVGRWIRTQQHYYEKDPKRIYYLSLEFY 91
>U47025-1|AAB60395.1| 843|Homo sapiens glycogen phosphorylase B
protein.
Length = 843
Score = 31.9 bits (69), Expect = 2.3
Identities = 16/51 (31%), Positives = 24/51 (47%)
Frame = +1
Query: 103 VSDKTPSTWDDYTHTQPHRIKDHSNGDVACDSYNQYEKDIEMAEQLGLDFY 255
V D+ +T DY H ++DH G + YE+D + L L+FY
Sbjct: 41 VKDRNVATPRDYFFALAHTVRDHLVGRWIRTQQHYYERDPKRIYYLSLEFY 91
>J03544-1|AAA59597.1| 863|Homo sapiens PYGB protein.
Length = 863
Score = 31.9 bits (69), Expect = 2.3
Identities = 16/51 (31%), Positives = 24/51 (47%)
Frame = +1
Query: 103 VSDKTPSTWDDYTHTQPHRIKDHSNGDVACDSYNQYEKDIEMAEQLGLDFY 255
V D+ +T DY H ++DH G + YE+D + L L+FY
Sbjct: 41 VKDRNVATPRDYFFALAHTVRDHLVGRWIRTQQHYYERDPKRIYYLSLEFY 91
>BC030795-1|AAH30795.1| 843|Homo sapiens phosphorylase, glycogen;
brain protein.
Length = 843
Score = 31.9 bits (69), Expect = 2.3
Identities = 16/51 (31%), Positives = 24/51 (47%)
Frame = +1
Query: 103 VSDKTPSTWDDYTHTQPHRIKDHSNGDVACDSYNQYEKDIEMAEQLGLDFY 255
V D+ +T DY H ++DH G + YE+D + L L+FY
Sbjct: 41 VKDRNVATPRDYFFALAHTVRDHLVGRWIRTQQHYYERDPKRIYYLSLEFY 91
>BC017045-1|AAH17045.1| 843|Homo sapiens phosphorylase, glycogen;
brain protein.
Length = 843
Score = 31.9 bits (69), Expect = 2.3
Identities = 16/51 (31%), Positives = 24/51 (47%)
Frame = +1
Query: 103 VSDKTPSTWDDYTHTQPHRIKDHSNGDVACDSYNQYEKDIEMAEQLGLDFY 255
V D+ +T DY H ++DH G + YE+D + L L+FY
Sbjct: 41 VKDRNVATPRDYFFALAHTVRDHLVGRWIRTQQHYYERDPKRIYYLSLEFY 91
>AL121772-1|CAC00661.1| 843|Homo sapiens phosphorylase, glycogen;
brain protein.
Length = 843
Score = 31.9 bits (69), Expect = 2.3
Identities = 16/51 (31%), Positives = 24/51 (47%)
Frame = +1
Query: 103 VSDKTPSTWDDYTHTQPHRIKDHSNGDVACDSYNQYEKDIEMAEQLGLDFY 255
V D+ +T DY H ++DH G + YE+D + L L+FY
Sbjct: 41 VKDRNVATPRDYFFALAHTVRDHLVGRWIRTQQHYYERDPKRIYYLSLEFY 91
>AB209080-1|BAD92317.1| 865|Homo sapiens brain glycogen
phosphorylase variant protein.
Length = 865
Score = 31.9 bits (69), Expect = 2.3
Identities = 16/51 (31%), Positives = 24/51 (47%)
Frame = +1
Query: 103 VSDKTPSTWDDYTHTQPHRIKDHSNGDVACDSYNQYEKDIEMAEQLGLDFY 255
V D+ +T DY H ++DH G + YE+D + L L+FY
Sbjct: 63 VKDRNVATPRDYFFALAHTVRDHLVGRWIRTQQHYYERDPKRIYYLSLEFY 113
>AK131337-1|BAD18495.1| 646|Homo sapiens protein ( Homo sapiens
cDNA FLJ16351 fis, clone TESTI2039060, moderately
similar to Maltase-glucoamylase, intestinal. ).
Length = 646
Score = 31.5 bits (68), Expect = 3.0
Identities = 25/76 (32%), Positives = 38/76 (50%), Gaps = 3/76 (3%)
Frame = +1
Query: 340 LINGLLDRGIEPMVTLYHSDM--PKIFQD-LGGWANPEMAEWFADYADVAFSLYGDRVKL 510
+++G LD E V LY + + P F++ W E+ E +A+ + SL D L
Sbjct: 244 IVDGSLDH--ETQVKLYRAYVAFPDFFRNSTAAWWKKEIEELYANPREPEKSLKFDG--L 299
Query: 511 WITINEPLHACDSSSR 558
WI +NEP + D S R
Sbjct: 300 WIDMNEPSNFVDGSVR 315
>AM079743-1|CAL03889.1| 101|Homo sapiens immunoglobulin heavy chain
variable region protein.
Length = 101
Score = 31.1 bits (67), Expect = 4.0
Identities = 18/41 (43%), Positives = 24/41 (58%), Gaps = 4/41 (9%)
Frame = +1
Query: 241 GLDFYRFSISWPRLLP-KGFR--TRIS-ADGRQYYDNLING 351
G F F++SW R P KG + IS ADGR YY++ + G
Sbjct: 29 GFSFSTFAVSWVRQAPGKGLEWVSFISGADGRTYYEDSVKG 69
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 110,642,186
Number of Sequences: 237096
Number of extensions: 2532094
Number of successful extensions: 5873
Number of sequences better than 10.0: 38
Number of HSP's better than 10.0 without gapping: 5627
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5843
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8063224416
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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