Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= bmmt21m15
(684 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X52710-1|CAA36934.1| 390|Homo sapiens protein ( Human mRNA for ... 193 6e-49
X52709-1|CAA36933.1| 390|Homo sapiens protein ( Human mRNA for ... 193 6e-49
M27257-1|AAA60051.1| 390|Homo sapiens pyruvate dehydrogenase E1... 193 6e-49
M24848-1|AAA36533.1| 390|Homo sapiens protein ( Human pyruvate ... 193 6e-49
L13318-1|AAA60227.1| 390|Homo sapiens pyruvate dehydrogenase E1... 193 6e-49
J03575-1|AAA60050.1| 390|Homo sapiens pyruvate dehydrogenase al... 193 6e-49
J03503-1|AAA60055.1| 414|Homo sapiens PDHA1 protein. 193 6e-49
D90084-1|BAA14121.1| 390|Homo sapiens pyruvate dehydrogenase al... 193 6e-49
BC002406-1|AAH02406.1| 390|Homo sapiens pyruvate dehydrogenase ... 193 6e-49
AL732326-7|CAI41291.1| 390|Homo sapiens pyruvate dehydrogenase ... 193 6e-49
AK222988-1|BAD96708.1| 390|Homo sapiens pyruvate dehydrogenase ... 193 6e-49
AK222740-1|BAD96460.1| 390|Homo sapiens pyruvate dehydrogenase ... 193 6e-49
EF590117-1|ABQ59099.1| 428|Homo sapiens mitochondrial PDHA1 pro... 188 1e-47
AL732326-5|CAI41289.1| 180|Homo sapiens pyruvate dehydrogenase ... 188 1e-47
AL732326-6|CAI41290.1| 204|Homo sapiens pyruvate dehydrogenase ... 184 3e-46
M86808-1|AAA60232.1| 388|Homo sapiens pyruvate dehydrogenase co... 177 4e-44
BC127638-1|AAI27639.1| 388|Homo sapiens pyruvate dehydrogenase ... 177 4e-44
BC127637-1|AAI27638.1| 388|Homo sapiens pyruvate dehydrogenase ... 177 4e-44
BC119657-1|AAI19658.1| 388|Homo sapiens pyruvate dehydrogenase ... 177 4e-44
BC119656-1|AAI19657.1| 388|Homo sapiens pyruvate dehydrogenase ... 177 4e-44
BC094760-1|AAH94760.1| 407|Homo sapiens PDHA2 protein protein. 177 4e-44
BC030697-1|AAH30697.3| 388|Homo sapiens pyruvate dehydrogenase ... 177 4e-44
AL732326-4|CAI41288.1| 205|Homo sapiens pyruvate dehydrogenase ... 176 5e-44
BC066953-1|AAH66953.2| 388|Homo sapiens pyruvate dehydrogenase ... 175 9e-44
L48690-1|AAB59581.1| 390|Homo sapiens pyruvate dehydrogenase E1... 93 1e-18
EF576990-1|ABQ58815.1| 261|Homo sapiens PDHA1 protein. 79 1e-14
AL732326-3|CAI41287.1| 121|Homo sapiens pyruvate dehydrogenase ... 77 8e-14
BC150265-1|AAI50266.1| 1481|Homo sapiens CRKRS protein protein. 34 0.54
AF227198-1|AAF36401.1| 1490|Homo sapiens CrkRS protein. 34 0.54
AB020711-1|BAA74927.2| 1535|Homo sapiens KIAA0904 protein protein. 34 0.54
AK130326-1|BAC85327.1| 508|Homo sapiens protein ( Homo sapiens ... 31 2.9
>X52710-1|CAA36934.1| 390|Homo sapiens protein ( Human mRNA for
liver pyruvate dehydrogenase (EC 1.2.4.1) E1' subunit.
).
Length = 390
Score = 193 bits (470), Expect = 6e-49
Identities = 89/176 (50%), Positives = 123/176 (69%)
Frame = +2
Query: 155 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 334
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 335 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 514
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 117
Query: 515 YRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQVPL 682
YR HG+T+ G+SV +L+ELTGR+ GC++GKGGSMH+Y +NFYGGNGIVGAQVPL
Sbjct: 118 YRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPL 173
>X52709-1|CAA36933.1| 390|Homo sapiens protein ( Human mRNA for
brain pyruvate dehydrogenase (EC 1.2.4.1). ).
Length = 390
Score = 193 bits (470), Expect = 6e-49
Identities = 89/176 (50%), Positives = 123/176 (69%)
Frame = +2
Query: 155 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 334
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 335 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 514
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 117
Query: 515 YRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQVPL 682
YR HG+T+ G+SV +L+ELTGR+ GC++GKGGSMH+Y +NFYGGNGIVGAQVPL
Sbjct: 118 YRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPL 173
>M27257-1|AAA60051.1| 390|Homo sapiens pyruvate dehydrogenase
E1-alpha subunit protein.
Length = 390
Score = 193 bits (470), Expect = 6e-49
Identities = 89/176 (50%), Positives = 123/176 (69%)
Frame = +2
Query: 155 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 334
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 335 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 514
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 117
Query: 515 YRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQVPL 682
YR HG+T+ G+SV +L+ELTGR+ GC++GKGGSMH+Y +NFYGGNGIVGAQVPL
Sbjct: 118 YRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPL 173
>M24848-1|AAA36533.1| 390|Homo sapiens protein ( Human pyruvate
dehydrogenase alpha subunit mRNA, complete cds. ).
Length = 390
Score = 193 bits (470), Expect = 6e-49
Identities = 89/176 (50%), Positives = 123/176 (69%)
Frame = +2
Query: 155 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 334
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 335 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 514
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 117
Query: 515 YRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQVPL 682
YR HG+T+ G+SV +L+ELTGR+ GC++GKGGSMH+Y +NFYGGNGIVGAQVPL
Sbjct: 118 YRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPL 173
>L13318-1|AAA60227.1| 390|Homo sapiens pyruvate dehydrogenase
E1-alpha subunit protein.
Length = 390
Score = 193 bits (470), Expect = 6e-49
Identities = 89/176 (50%), Positives = 123/176 (69%)
Frame = +2
Query: 155 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 334
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 335 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 514
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 117
Query: 515 YRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQVPL 682
YR HG+T+ G+SV +L+ELTGR+ GC++GKGGSMH+Y +NFYGGNGIVGAQVPL
Sbjct: 118 YRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPL 173
>J03575-1|AAA60050.1| 390|Homo sapiens pyruvate dehydrogenase alpha
subunit protein.
Length = 390
Score = 193 bits (470), Expect = 6e-49
Identities = 89/176 (50%), Positives = 123/176 (69%)
Frame = +2
Query: 155 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 334
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 335 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 514
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 117
Query: 515 YRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQVPL 682
YR HG+T+ G+SV +L+ELTGR+ GC++GKGGSMH+Y +NFYGGNGIVGAQVPL
Sbjct: 118 YRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPL 173
>J03503-1|AAA60055.1| 414|Homo sapiens PDHA1 protein.
Length = 414
Score = 193 bits (470), Expect = 6e-49
Identities = 89/176 (50%), Positives = 123/176 (69%)
Frame = +2
Query: 155 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 334
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 25 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 81
Query: 335 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 514
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 82 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 141
Query: 515 YRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQVPL 682
YR HG+T+ G+SV +L+ELTGR+ GC++GKGGSMH+Y +NFYGGNGIVGAQVPL
Sbjct: 142 YRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPL 197
>D90084-1|BAA14121.1| 390|Homo sapiens pyruvate dehydrogenase alpha
subunit protein.
Length = 390
Score = 193 bits (470), Expect = 6e-49
Identities = 89/176 (50%), Positives = 123/176 (69%)
Frame = +2
Query: 155 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 334
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 335 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 514
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 117
Query: 515 YRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQVPL 682
YR HG+T+ G+SV +L+ELTGR+ GC++GKGGSMH+Y +NFYGGNGIVGAQVPL
Sbjct: 118 YRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPL 173
>BC002406-1|AAH02406.1| 390|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 1 protein.
Length = 390
Score = 193 bits (470), Expect = 6e-49
Identities = 89/176 (50%), Positives = 123/176 (69%)
Frame = +2
Query: 155 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 334
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 335 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 514
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 117
Query: 515 YRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQVPL 682
YR HG+T+ G+SV +L+ELTGR+ GC++GKGGSMH+Y +NFYGGNGIVGAQVPL
Sbjct: 118 YRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPL 173
>AL732326-7|CAI41291.1| 390|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 1 protein.
Length = 390
Score = 193 bits (470), Expect = 6e-49
Identities = 89/176 (50%), Positives = 123/176 (69%)
Frame = +2
Query: 155 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 334
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 335 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 514
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 117
Query: 515 YRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQVPL 682
YR HG+T+ G+SV +L+ELTGR+ GC++GKGGSMH+Y +NFYGGNGIVGAQVPL
Sbjct: 118 YRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPL 173
>AK222988-1|BAD96708.1| 390|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 1 variant protein.
Length = 390
Score = 193 bits (470), Expect = 6e-49
Identities = 89/176 (50%), Positives = 123/176 (69%)
Frame = +2
Query: 155 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 334
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 335 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 514
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 117
Query: 515 YRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQVPL 682
YR HG+T+ G+SV +L+ELTGR+ GC++GKGGSMH+Y +NFYGGNGIVGAQVPL
Sbjct: 118 YRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPL 173
>AK222740-1|BAD96460.1| 390|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 1 variant protein.
Length = 390
Score = 193 bits (470), Expect = 6e-49
Identities = 89/176 (50%), Positives = 123/176 (69%)
Frame = +2
Query: 155 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 334
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 335 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 514
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 117
Query: 515 YRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQVPL 682
YR HG+T+ G+SV +L+ELTGR+ GC++GKGGSMH+Y +NFYGGNGIVGAQVPL
Sbjct: 118 YRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPL 173
>EF590117-1|ABQ59099.1| 428|Homo sapiens mitochondrial PDHA1
protein.
Length = 428
Score = 188 bits (459), Expect = 1e-47
Identities = 83/141 (58%), Positives = 106/141 (75%)
Frame = +2
Query: 260 EATFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCH 439
+ATFEIK LH+L++GP + LT ED LK Y + +RR+E + LYK+KIIRGFCH
Sbjct: 71 DATFEIKKCDLHRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCH 130
Query: 440 LYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGS 619
L GQEA VG+ A + D +ITAYR HG+T+ G+SV +L+ELTGR+ GC++GKGGS
Sbjct: 131 LCDGQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGS 190
Query: 620 MHLYGRNFYGGNGIVGAQVPL 682
MH+Y +NFYGGNGIVGAQVPL
Sbjct: 191 MHMYAKNFYGGNGIVGAQVPL 211
>AL732326-5|CAI41289.1| 180|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 1 protein.
Length = 180
Score = 188 bits (459), Expect = 1e-47
Identities = 87/174 (50%), Positives = 121/174 (69%)
Frame = +2
Query: 155 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 334
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 335 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 514
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 117
Query: 515 YRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQV 676
YR HG+T+ G+SV +L+ELTGR+ GC++GKGGSMH+Y +NFYGGNGIVGAQV
Sbjct: 118 YRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQV 171
>AL732326-6|CAI41290.1| 204|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 1 protein.
Length = 204
Score = 184 bits (447), Expect = 3e-46
Identities = 89/183 (48%), Positives = 123/183 (67%), Gaps = 7/183 (3%)
Frame = +2
Query: 155 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 334
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 335 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQ-------EAVAVGMRAAMRD 493
ED LK Y + +RR+E + LYK+KIIRGFCHL GQ EA VG+ A +
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQFLLPLTQEACCVGLEAGINP 117
Query: 494 ADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQ 673
D +ITAYR HG+T+ G+SV +L+ELTGR+ GC++GKGGSMH+Y +NFYGGNGIVGAQ
Sbjct: 118 TDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQ 177
Query: 674 VPL 682
VPL
Sbjct: 178 VPL 180
>M86808-1|AAA60232.1| 388|Homo sapiens pyruvate dehydrogenase
complex protein.
Length = 388
Score = 177 bits (430), Expect = 4e-44
Identities = 80/148 (54%), Positives = 104/148 (70%)
Frame = +2
Query: 239 AKYSTKKEATFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEK 418
A ++ +ATFEIK L+ L++GP + LT + LK Y + +RR+E + LYK+K
Sbjct: 24 ASRNSSNDATFEIKKCDLYLLEEGPPVTTVLTRAEGLKYYRMMLTVRRMELKADQLYKQK 83
Query: 419 IIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGC 598
IRGFCHL GQEA VG+ A + +D VIT+YR HG Y G+SV +L+ELTGRR GC
Sbjct: 84 FIRGFCHLCDGQEACCVGLEAGINPSDHVITSYRAHGVCYTRGLSVRSILAELTGRRGGC 143
Query: 599 SRGKGGSMHLYGRNFYGGNGIVGAQVPL 682
++GKGGSMH+Y +NFYGGNGIVGAQ PL
Sbjct: 144 AKGKGGSMHMYTKNFYGGNGIVGAQGPL 171
>BC127638-1|AAI27639.1| 388|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 2 protein.
Length = 388
Score = 177 bits (430), Expect = 4e-44
Identities = 80/148 (54%), Positives = 104/148 (70%)
Frame = +2
Query: 239 AKYSTKKEATFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEK 418
A ++ +ATFEIK L+ L++GP + LT + LK Y + +RR+E + LYK+K
Sbjct: 24 ASRNSSNDATFEIKKCDLYLLEEGPPVTTVLTRAEGLKYYRMMLTVRRMELKADQLYKQK 83
Query: 419 IIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGC 598
IRGFCHL GQEA VG+ A + +D VIT+YR HG Y G+SV +L+ELTGRR GC
Sbjct: 84 FIRGFCHLCDGQEACCVGLEAGINPSDHVITSYRAHGVCYTRGLSVRSILAELTGRRGGC 143
Query: 599 SRGKGGSMHLYGRNFYGGNGIVGAQVPL 682
++GKGGSMH+Y +NFYGGNGIVGAQ PL
Sbjct: 144 AKGKGGSMHMYTKNFYGGNGIVGAQGPL 171
>BC127637-1|AAI27638.1| 388|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 2 protein.
Length = 388
Score = 177 bits (430), Expect = 4e-44
Identities = 80/148 (54%), Positives = 104/148 (70%)
Frame = +2
Query: 239 AKYSTKKEATFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEK 418
A ++ +ATFEIK L+ L++GP + LT + LK Y + +RR+E + LYK+K
Sbjct: 24 ASRNSSNDATFEIKKCDLYLLEEGPPVTTVLTRAEGLKYYRMMLTVRRMELKADQLYKQK 83
Query: 419 IIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGC 598
IRGFCHL GQEA VG+ A + +D VIT+YR HG Y G+SV +L+ELTGRR GC
Sbjct: 84 FIRGFCHLCDGQEACCVGLEAGINPSDHVITSYRAHGVCYTRGLSVRSILAELTGRRGGC 143
Query: 599 SRGKGGSMHLYGRNFYGGNGIVGAQVPL 682
++GKGGSMH+Y +NFYGGNGIVGAQ PL
Sbjct: 144 AKGKGGSMHMYTKNFYGGNGIVGAQGPL 171
>BC119657-1|AAI19658.1| 388|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 2 protein.
Length = 388
Score = 177 bits (430), Expect = 4e-44
Identities = 80/148 (54%), Positives = 104/148 (70%)
Frame = +2
Query: 239 AKYSTKKEATFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEK 418
A ++ +ATFEIK L+ L++GP + LT + LK Y + +RR+E + LYK+K
Sbjct: 24 ASRNSSNDATFEIKKCDLYLLEEGPPVTTVLTRAEGLKYYRMMLTVRRMELKADQLYKQK 83
Query: 419 IIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGC 598
IRGFCHL GQEA VG+ A + +D VIT+YR HG Y G+SV +L+ELTGRR GC
Sbjct: 84 FIRGFCHLCDGQEACCVGLEAGINPSDHVITSYRAHGVCYTRGLSVRSILAELTGRRGGC 143
Query: 599 SRGKGGSMHLYGRNFYGGNGIVGAQVPL 682
++GKGGSMH+Y +NFYGGNGIVGAQ PL
Sbjct: 144 AKGKGGSMHMYTKNFYGGNGIVGAQGPL 171
>BC119656-1|AAI19657.1| 388|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 2 protein.
Length = 388
Score = 177 bits (430), Expect = 4e-44
Identities = 80/148 (54%), Positives = 104/148 (70%)
Frame = +2
Query: 239 AKYSTKKEATFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEK 418
A ++ +ATFEIK L+ L++GP + LT + LK Y + +RR+E + LYK+K
Sbjct: 24 ASRNSSNDATFEIKKCDLYLLEEGPPVTTVLTRAEGLKYYRMMLTVRRMELKADQLYKQK 83
Query: 419 IIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGC 598
IRGFCHL GQEA VG+ A + +D VIT+YR HG Y G+SV +L+ELTGRR GC
Sbjct: 84 FIRGFCHLCDGQEACCVGLEAGINPSDHVITSYRAHGVCYTRGLSVRSILAELTGRRGGC 143
Query: 599 SRGKGGSMHLYGRNFYGGNGIVGAQVPL 682
++GKGGSMH+Y +NFYGGNGIVGAQ PL
Sbjct: 144 AKGKGGSMHMYTKNFYGGNGIVGAQGPL 171
>BC094760-1|AAH94760.1| 407|Homo sapiens PDHA2 protein protein.
Length = 407
Score = 177 bits (430), Expect = 4e-44
Identities = 80/148 (54%), Positives = 104/148 (70%)
Frame = +2
Query: 239 AKYSTKKEATFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEK 418
A ++ +ATFEIK L+ L++GP + LT + LK Y + +RR+E + LYK+K
Sbjct: 43 ASRNSSNDATFEIKKCDLYLLEEGPPVTTVLTRAEGLKYYRMMLTVRRMELKADQLYKQK 102
Query: 419 IIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGC 598
IRGFCHL GQEA VG+ A + +D VIT+YR HG Y G+SV +L+ELTGRR GC
Sbjct: 103 FIRGFCHLCDGQEACCVGLEAGINPSDHVITSYRAHGVCYTRGLSVRSILAELTGRRGGC 162
Query: 599 SRGKGGSMHLYGRNFYGGNGIVGAQVPL 682
++GKGGSMH+Y +NFYGGNGIVGAQ PL
Sbjct: 163 AKGKGGSMHMYTKNFYGGNGIVGAQGPL 190
>BC030697-1|AAH30697.3| 388|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 2 protein.
Length = 388
Score = 177 bits (430), Expect = 4e-44
Identities = 80/148 (54%), Positives = 104/148 (70%)
Frame = +2
Query: 239 AKYSTKKEATFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEK 418
A ++ +ATFEIK L+ L++GP + LT + LK Y + +RR+E + LYK+K
Sbjct: 24 ASRNSSNDATFEIKKCDLYLLEEGPPVTTVLTRAEGLKYYRMMLTVRRMELKADQLYKQK 83
Query: 419 IIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGC 598
IRGFCHL GQEA VG+ A + +D VIT+YR HG Y G+SV +L+ELTGRR GC
Sbjct: 84 FIRGFCHLCDGQEACCVGLEAGINPSDHVITSYRAHGVCYTRGLSVRSILAELTGRRGGC 143
Query: 599 SRGKGGSMHLYGRNFYGGNGIVGAQVPL 682
++GKGGSMH+Y +NFYGGNGIVGAQ PL
Sbjct: 144 AKGKGGSMHMYTKNFYGGNGIVGAQGPL 171
>AL732326-4|CAI41288.1| 205|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 1 protein.
Length = 205
Score = 176 bits (429), Expect = 5e-44
Identities = 77/135 (57%), Positives = 100/135 (74%)
Frame = +2
Query: 260 EATFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCH 439
+ATFEIK LH+L++GP + LT ED LK Y + +RR+E + LYK+KIIRGFCH
Sbjct: 71 DATFEIKKCDLHRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCH 130
Query: 440 LYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGS 619
L GQEA VG+ A + D +ITAYR HG+T+ G+SV +L+ELTGR+ GC++GKGGS
Sbjct: 131 LCDGQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGS 190
Query: 620 MHLYGRNFYGGNGIV 664
MH+Y +NFYGGNGIV
Sbjct: 191 MHMYAKNFYGGNGIV 205
>BC066953-1|AAH66953.2| 388|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 2 protein.
Length = 388
Score = 175 bits (427), Expect = 9e-44
Identities = 80/148 (54%), Positives = 103/148 (69%)
Frame = +2
Query: 239 AKYSTKKEATFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEK 418
A ++ +ATFEIK L+ L++GP + LT + LK Y + +RR+E + LYK+K
Sbjct: 24 ASRNSSNDATFEIKKCDLYLLEEGPPVTTVLTRAEGLKYYRMMLTVRRMELKADQLYKQK 83
Query: 419 IIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGC 598
IRGFCHL GQEA VG+ A + +D VIT+YR HG Y G SV +L+ELTGRR GC
Sbjct: 84 FIRGFCHLCDGQEACCVGLEAGINPSDHVITSYRAHGVCYTRGPSVRSILAELTGRRGGC 143
Query: 599 SRGKGGSMHLYGRNFYGGNGIVGAQVPL 682
++GKGGSMH+Y +NFYGGNGIVGAQ PL
Sbjct: 144 AKGKGGSMHMYTKNFYGGNGIVGAQGPL 171
>L48690-1|AAB59581.1| 390|Homo sapiens pyruvate dehydrogenase
E1-alpha subunit precursor protein.
Length = 390
Score = 92.7 bits (220), Expect = 1e-18
Identities = 46/110 (41%), Positives = 67/110 (60%)
Frame = +2
Query: 155 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 334
M K++ + + L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSPVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 335 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAA 484
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLERA 107
>EF576990-1|ABQ58815.1| 261|Homo sapiens PDHA1 protein.
Length = 261
Score = 79.4 bits (187), Expect = 1e-14
Identities = 33/44 (75%), Positives = 40/44 (90%)
Frame = +2
Query: 551 SVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQVPL 682
SV +L+ELTGR+ GC++GKGGSMH+Y +NFYGGNGIVGAQVPL
Sbjct: 1 SVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPL 44
>AL732326-3|CAI41287.1| 121|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 1 protein.
Length = 121
Score = 76.6 bits (180), Expect = 8e-14
Identities = 33/61 (54%), Positives = 43/61 (70%)
Frame = +2
Query: 260 EATFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCH 439
+ATFEIK LH+L++GP + LT ED LK Y + +RR+E + LYK+KIIRGFCH
Sbjct: 61 DATFEIKKCDLHRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCH 120
Query: 440 L 442
L
Sbjct: 121 L 121
>BC150265-1|AAI50266.1| 1481|Homo sapiens CRKRS protein protein.
Length = 1481
Score = 33.9 bits (74), Expect = 0.54
Identities = 22/48 (45%), Positives = 24/48 (50%), Gaps = 1/48 (2%)
Frame = -1
Query: 684 PNGTCAP-TIPLPP*KLRPYKCMEPPLPREQPVLRPVSSESTPSTLTP 544
P T P T PLPP P +PPLP QP V + ST STL P
Sbjct: 540 PTTTPPPQTPPLPPLPPIPALPQQPPLPPSQPAFSQVPASST-STLPP 586
>AF227198-1|AAF36401.1| 1490|Homo sapiens CrkRS protein.
Length = 1490
Score = 33.9 bits (74), Expect = 0.54
Identities = 22/48 (45%), Positives = 24/48 (50%), Gaps = 1/48 (2%)
Frame = -1
Query: 684 PNGTCAP-TIPLPP*KLRPYKCMEPPLPREQPVLRPVSSESTPSTLTP 544
P T P T PLPP P +PPLP QP V + ST STL P
Sbjct: 540 PTTTPPPQTPPLPPLPPIPALPQQPPLPPSQPAFSQVPASST-STLPP 586
>AB020711-1|BAA74927.2| 1535|Homo sapiens KIAA0904 protein protein.
Length = 1535
Score = 33.9 bits (74), Expect = 0.54
Identities = 22/48 (45%), Positives = 24/48 (50%), Gaps = 1/48 (2%)
Frame = -1
Query: 684 PNGTCAP-TIPLPP*KLRPYKCMEPPLPREQPVLRPVSSESTPSTLTP 544
P T P T PLPP P +PPLP QP V + ST STL P
Sbjct: 594 PTTTPPPQTPPLPPLPPIPALPQQPPLPPSQPAFSQVPASST-STLPP 640
>AK130326-1|BAC85327.1| 508|Homo sapiens protein ( Homo sapiens
cDNA FLJ26816 fis, clone PRS06437. ).
Length = 508
Score = 31.5 bits (68), Expect = 2.9
Identities = 22/60 (36%), Positives = 30/60 (50%), Gaps = 1/60 (1%)
Frame = -1
Query: 651 PP*KLRPYKCMEP-PLPREQPVLRPVSSESTPSTLTPMR*VHP*QRYAVITESASRIAAL 475
PP KL+P +P P + QP L P ++ P T TP HP Q + + E S + AL
Sbjct: 402 PPPKLQPQPQPQPQPQSQPQPQLPP-QPQTQPQTPTPAP-QHPQQTWPPVNEGESAMRAL 459
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 101,749,090
Number of Sequences: 237096
Number of extensions: 2107322
Number of successful extensions: 6727
Number of sequences better than 10.0: 31
Number of HSP's better than 10.0 without gapping: 6138
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6697
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 7783251346
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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